lokahq/bioreason-rl huggingface dataset:
Protein: D-gluconate dehydratase (EC 4.2.1.39) (Q704D2)
Organism: Thermoproteus tenax
Function: Involved in the degradation of glucose via the Entner-Doudoroff pathway. Catalyzes the dehydration of gluconate to produce 2-keto-3-deoxygluconate (KDG). It is not able to use D-galactonate as substrate.
InterPro domains:
- IPR029065: Enolase C-terminal domain-like (domain) [248-470]
- IPR018110: Mandelate racemase/muconate lactonizing enzyme, conserved site (conserved_site) [199-224]
- IPR013341: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain (domain) [132-224]
- IPR034599: Gluconate dehydratase (family) [109-497]
- IPR013342: Mandelate racemase/muconate lactonizing enzyme, C-terminal (domain) [245-350]
- IPR029017: Enolase-like, N-terminal (homologous_superfamily) [111-472]
- IPR034593: D-galactonate dehydratase DgoD-like (family) [109-478]
- IPR036849: Enolase-like, C-terminal domain superfamily (homologous_superfamily) [212-478]
Sequence:
MASAMASSALREATCTMTRLAADVAASVSSIFSCKDSAGPRPVVPATKTTSTPLDVMFFTWFAKSSGSSLPPLKVVMTGATISIDSTRGALKKLARKGIKGWLNQYMATIKEIEPIVLYEQETDARWASYSILVRVVTSDGRVSYGEAVPTLRILPVVSAVRQTARAFLGRDPHEISAAFYEWYRQDFFLSRSFESATALSAIDMALWDLKARELGAPLYELLGGKLRDRVKVYANGWYGGCRDPQCFAEKAKEVVARGYDALKFDPFGPSFNSITSEELRRAEEAVAAVRDAVGDDVDILIEHHGRFNANAAVEIAKRFEPYRPYFMEEPLHHEDIEGYRKYRSLTSARIAMGERLISAKEALQYLVEGLVDVIQPDACNIGGVTGSMKVAALAEAFSVEVSYHNAYGPVQFALEVQLSAVTPTLYRLESFYDYWPQWKRDLIGDPFRLSQSSVEVPRGPGIGVAVNERVLEKYRAEPSEIPVGEEPVWVVRGTWR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016835 (carbon-oxygen lyase activity), GO:0016836 (hydro-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009056 (catabolic process), GO:0044237 (cellular metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:1901575 (organic substance catabolic process), GO:0044248 (cellular catabolic process), GO:0005975 (carbohydrate metabolic process), GO:0044262 (cellular carbohydrate metabolic process), GO:0016052 (carbohydrate catabolic process), GO:0044275 (cellular carbohydrate catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Large ribosomal subunit protein mL46 (39S ribosomal protein L46, mitochondrial) (L46mt) (MRP-L46) (Q9EQI8)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q9H2W6}.
InterPro domains:
- IPR033650: Large ribosomal subunit protein mL46, NUDIX domain (domain) [134-273]
- IPR021757: Large ribosomal subunit protein mL46, N-terminal (domain) [43-139]
- IPR040008: Large ribosomal subunit protein mL46 (family) [33-276]
- IPR015797: NUDIX hydrolase-like domain superfamily (homologous_superfamily) [152-276]
Sequence:
MAAPVGRTLLGLARGWRQLDRFWAGSSRGLSLEAASSSSRSPWRLSGALCLQRPPLITKALTPLQEEMAGLLQQIEVERSLYSDHELRALDEAQRLAKKKADLYDEEQEQGITLAQDLEDMWEQAFLQFRPGARETEADKKNDRTSLHRKLDRNLVLLVREKLGDQDVWMLPQVEWQPGETLRGTAERILATLSENNMEAKFLGNAPCGHYKFKFPKAIQTESDLGVKVFFFKALLLTGDFVQAGKKSRHVWASKEELGDYLQPKYLAQVRRFLLDSDGLSCL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0019538 (protein metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006412 (translation), GO:0009059 (macromolecule biosynthetic process), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:0006518 (peptide metabolic process), GO:0010467 (gene expression), GO:0140053 (mitochondrial gene expression), GO:0043043 (peptide biosynthetic process), GO:0032543 (mitochondrial translation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: C-type lectin domain family 18 member C (Mannose receptor-like protein 3) (Q8NCF0)
Organism: Homo sapiens (Human)
Function: Binds polysaccharidesin a Ca(2+)-independent manner with a preferentially binding to fucoidan, beta-glucans and galactans.
Subcellular location: Secreted {ECO:0000250|UniProtKB:A5D8T8}. Endoplasmic reticulum {ECO:0000305|PubMed:26170455}. Golgi apparatus {ECO:0000305|PubMed:26170455}. Endosome {ECO:0000305|PubMed:26170455}.
InterPro domains:
- IPR001283: Cysteine-rich secretory protein-related (family) [51-204]
- IPR016186: C-type lectin-like/link domain superfamily (homologous_superfamily) [296-434]
- IPR018378: C-type lectin, conserved site (conserved_site) [408-432]
- IPR016187: C-type lectin fold (homologous_superfamily) [303-436]
- IPR001304: C-type lectin-like (domain) [297-434]
- IPR035940: CAP superfamily (homologous_superfamily) [14-225]
- IPR000742: EGF-like domain (domain) [228-292]
- IPR014044: CAP domain (domain) [44-190]
Sequence:
MLHPETSPGRGHLLAVLLALLGTAWAEVWPPQLQEQAPMAGALNRKESFLLLSLHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALCGIPTPSLASGLWRTLQVGWNMQLLPAGLASFVEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQAAIEAFVCAYSPRGNWEVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHGRLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCATKVHFPFHTCDLRIDGDCFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVIDSDFETRNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNHGFGNCVELQASAAFNWNNQRCKTRNRYICQFAQEHISRWGPGS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0030246 (carbohydrate binding), GO:0005515 (protein binding), GO:0030247 (polysaccharide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0016192 (vesicle-mediated transport), GO:0006909 (phagocytosis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005615 (extracellular space), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005576 (extracellular region), GO:0005794 (Golgi apparatus), GO:0005783 (endoplasmic reticulum), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)
Protein: SAFB like transcription modulator (H0YL55)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
InterPro domains:
- IPR051738: Scaffold Attachment Factor and Modulators (family) [10-225]
- IPR003034: SAP domain (domain) [22-57]
- IPR036361: SAP domain superfamily (homologous_superfamily) [7-66]
Sequence:
MAAATGAVAASAASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLISRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDSEASKPKDGQDAIAQSPEKESKDYEMNANHKD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003723 (RNA binding), GO:0003690 (double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0006357 (regulation of transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0016604 (nuclear body), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Nuclear speckle splicing regulatory protein 1 (Coiled-coil domain-containing protein 55) (Nuclear speckle-related protein 70) (NSrp70) (Q9H0G5)
Organism: Homo sapiens (Human)
Function: RNA-binding protein that mediates pre-mRNA alternative splicing regulation.
Subcellular location: Nucleus {ECO:0000269|PubMed:21296756}. Nucleus speckle {ECO:0000269|PubMed:21296756}. Note=Colocalizes with splicing factors SRSF1 and SRSF2 in speckles.
InterPro domains:
- IPR018612: Nuclear speckle splicing regulatory protein 1, N-terminal (domain) [59-177]
- IPR046850: Nuclear speckle splicing regulatory protein 1, RS-like domain (domain) [293-470]
- IPR042816: Nuclear speckle splicing regulatory protein 1 (family) [1-558]
Sequence:
MAIPGRQYGLILPKKTQQLHPVLQKPSVFGNDSDDDDETSVSESLQREAAKKQAMKQTKLEIQKALAEDATVYEYDSIYDEMQKKKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFVTSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSFREARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADDEIEETRVNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQSRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDREKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGVQSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTEEGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVNAKTYIEKEDD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0001501 (skeletal system development), GO:0060348 (bone development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Mitochrondria associated protein (T3SS secreted effector Map) (Q7DB76)
Organism: Escherichia coli O157:H7
Function: Not known
InterPro domains:
- IPR004959: Bacterial effector protein IpgB-like (family) [49-184]
Sequence:
MFSPMTMAGRSLVQATAQTLKPAVTRAAMQAGTGATGMRFMPVQSNFVINHGKLTNQLLQAVAKQTRNGDTQQWFQQEQTTYISRTVNRTLDDYCRSNNSVISKETKGHIFRAVENALQQPLDMNGAQSSIGHFLQSNKYFNQKVDEQCGKRVDPITRFNTQTKMIEQVSQEIFERNFSGFKVSEIKAITQNAILEHVQDTRL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0051051 (negative regulation of transport), GO:0048522 (positive regulation of cellular process), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0040013 (negative regulation of locomotion), GO:0048523 (negative regulation of cellular process), GO:0051050 (positive regulation of transport), GO:1903829 (positive regulation of protein localization), GO:0051049 (regulation of transport), GO:0051129 (negative regulation of cellular component organization), GO:2000145 (regulation of cell motility), GO:0045806 (negative regulation of endocytosis), GO:0060341 (regulation of cellular localization), GO:0032387 (negative regulation of intracellular transport), GO:2000146 (negative regulation of cell motility), GO:0051223 (regulation of protein transport), GO:0032880 (regulation of protein localization), GO:0030334 (regulation of cell migration), GO:0030336 (negative regulation of cell migration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Olfactomedin 2 (K7EIS8)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}. Synapse {ECO:0000256|ARBA:ARBA00034103}.
InterPro domains:
- IPR050605: Olfactomedin-like domain-containing protein (family) [3-365]
- IPR022082: Noelin domain (domain) [1-43]
- IPR003112: Olfactomedin-like domain (domain) [116-368]
Sequence:
MEVLELRTYRDLQYVRGMETLMRSLDARLRAADGSLSAKSFQELKDRMTELLPLSSVLEQYKADTRTIVRLREEVRNLSGSLAAIQEEMGAYGYEDLQQRVMALEARLHACAQKLGCGKLTGVSNPITVRAMGSRFGSWMTDTMAPSADSRVWYMDGYYKGRRVLEFRTLGDFIKGQNFIQHLLPQPWAGTGHVVYNGSLFYNKYQSNVVVKYHFRSRSVLVQRSLPGAGYNNTFPYSWGGFSDMDFMVDESGLWAVYTTNQNAGNIVVSRLDPHTLEVMRSWDTGYPKRSAGEAFMICGVLYVTNSHLAGAKVYFAYFTNTSSYEYTDVPFHNQYSHISMLDYNPRERALYTWNNGHQVLYNVTLFHVISTSGDP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0050793 (regulation of developmental process), GO:0140352 (export from cell), GO:0051094 (positive regulation of developmental process), GO:0033036 (macromolecule localization), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0070727 (cellular macromolecule localization), GO:0045597 (positive regulation of cell differentiation), GO:0045595 (regulation of cell differentiation), GO:0032940 (secretion by cell), GO:0045184 (establishment of protein localization), GO:0006810 (transport), GO:0051149 (positive regulation of muscle cell differentiation), GO:0035592 (establishment of protein localization to extracellular region), GO:0071702 (organic substance transport), GO:0046903 (secretion), GO:0008104 (protein localization), GO:0071705 (nitrogen compound transport), GO:0009306 (protein secretion), GO:0051147 (regulation of muscle cell differentiation), GO:0015031 (protein transport), GO:0051150 (regulation of smooth muscle cell differentiation), GO:0071692 (protein localization to extracellular region)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0005576 (extracellular region), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Tyrosine-protein phosphatase 2 (EC 3.1.3.48) (Protein-tyrosine-phosphate phosphohydrolase 2) (PTPA) (P34138)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Not known
InterPro domains:
- IPR029021: Protein-tyrosine phosphatase-like (homologous_superfamily) [13-366]
- IPR000387: Tyrosine-specific protein phosphatases domain (domain) [262-338]
- IPR050348: Protein-Tyrosine Phosphatase (family) [23-356]
- IPR003595: Protein-tyrosine phosphatase, catalytic (domain) [240-346]
- IPR016130: Protein-tyrosine phosphatase, active site (active_site) [279-289]
- IPR000242: Tyrosine-specific protein phosphatase, PTPase domain (domain) [26-349]
Sequence:
MDESFDAFEIKPNSSIIEHFNNHPTCIDKEFNFILQKTELRALETDKFRSALEAKNKLKNRYSNVLPFEETRVKINIDDDDDDEDDNEDDIIVSNNNNNNNNNEKRIKRNSIGSSGQSDVMSNSSDEEDHGGSGDEGTTLSDYINASFINNGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGNFIVKFDNNITIPDILIRREFTLENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYDEKKQAPSINLPKLVVEMRNERPGMVQTRDQYRFCYLAISEAMNTVLKKEQKKRKGLSYSYSSIPLTGPEHD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0004721 (phosphoprotein phosphatase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0004725 (protein tyrosine phosphatase activity), GO:0016791 (phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0035556 (intracellular signal transduction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Juvenile hormone binding protein 5, isoform C (A0A126GUV0)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
InterPro domains:
- IPR010562: Haemolymph juvenile hormone binding (family) [26-263]
- IPR038606: Takeout superfamily (homologous_superfamily) [38-261]
Sequence:
MNQYFLTGLLLVLGVVLHIDWTTAKPPAKKADQLPSFLKVCHRNAPDLDTCVRESYEELRPRLMEGIPELYIPAMEPLVVPQVKMDQDSGAIYLHSVYRNVKVTGISKHTVNELRLEPSKLKFILSLTFPKLHMESDYSIKVSREGKIMMMPLLGDGHCKVDLVNITMRTELIGQEYKKNGANFLKINTVKVKYELSDVHIHLDNLFNGDKALGDRMNEFLNENWKALAEEVRPLMTKALVDILRASVDKLFASFSYDDLLPM
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0036094 (small molecule binding), GO:0008289 (lipid binding), GO:0005319 (lipid transporter activity), GO:0050997 (quaternary ammonium group binding), GO:0097159 (organic cyclic compound binding), GO:0043167 (ion binding), GO:0043178 (alcohol binding), GO:0005496 (steroid binding), GO:0005543 (phospholipid binding), GO:0031210 (phosphatidylcholine binding), GO:0005548 (phospholipid transporter activity), GO:0043169 (cation binding), GO:0120013 (lipid transfer activity), GO:0015248 (sterol transporter activity), GO:0120015 (sterol transfer activity), GO:0015485 (cholesterol binding), GO:0032934 (sterol binding), GO:0120020 (cholesterol transfer activity)
Biological Process (BP): GO:0008150 (biological process), GO:0000003 (reproduction), GO:0019953 (sexual reproduction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Regulator of nucleoside diphosphate kinase (P0AFW4)
Organism: Escherichia coli (strain K12)
Function: May act as an anti-Gre factor. Regulates the level of the nucleoside diphosphate kinase Ndk.
InterPro domains:
- IPR001437: Transcription elongation factor, GreA/GreB, C-terminal (domain) [50-126]
- IPR029462: Regulator of nucleoside diphosphate kinase, N-terminal domain (domain) [4-42]
- IPR036953: Transcription elongation factor GreA/GreB, C-terminal domain superfamily (homologous_superfamily) [45-136]
- IPR023459: Transcription elongation factor GreA/GreB family (family) [32-128]
- IPR028625: Regulator of nucleoside diphosphate kinase (family) [1-136]
Sequence:
MSRPTIIINDLDAERIDILLEQPAYAGLPIADALNAELDRAQMCSPEEMPHDVVTMNSRVKFRNLSDGEVRVRTLVYPAKMTDSNTQLSVMAPVGAALLGLRVGDSIHWELPGGVATHLEVLELEYQPEAAGDYLL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0006082 (organic acid metabolic process), GO:0006631 (fatty acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0016053 (organic acid biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0006633 (fatty acid biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0046394 (carboxylic acid biosynthetic process), GO:0072330 (monocarboxylic acid biosynthetic process), GO:0032787 (monocarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:0005667 (transcription regulator complex)