lokahq/bioreason-rl huggingface dataset:
Protein: LD23533p (Q8T069)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
InterPro domains:
- IPR016024: Armadillo-type fold (homologous_superfamily) [12-536]
- IPR048411: Huntingtin, N-terminal, HEAT repeats 1 (repeat) [62-213]
- IPR011989: Armadillo-like helical (homologous_superfamily) [7-347]
- IPR028426: Huntingtin family (family) [7-620]
Sequence:
MDKSRSSAYDKFVGFVEQLRNTECSQKQKITCFQQIAECIMSPSLAGHINYAAHCGTATNVLLLFCEDVDSVVRMSAEENLNKILRSLEKTRVSRILMDLYGEIKRNGNQRSLRICLNLFSYYAPQIKEKHIKWYAVRLLQCMTTISQRKETLLQETLCDFVKHFSRHIQQGLSDSESCKLFETFLDQISSDCAVKRRCSAQNCMSLIENARNRSLMARHGVNKVMELLLTDQQANSVLGALGLLRLLLPQLIRGYPGDSHEDSESLAGKKQQQQQTTTSDCRQIIEIYDYCLHLLSTQHTANHAIINATLEVINGILQAVDAASDGQCSQSLGQSLRQLLCNQQLQHNEYLRRRKSLKNQIFQLKNYEVATSQHQLEDEDENEDVDELVVGATAMQMKKNSNAKLQQAKCREQQQHQHQQQLEVDNSSLGINAGEDAPTEAPSSVADEGGEPESTKLRCHIRNAARSISECVASDEDKQGQGHRQQRDEDGVVVAEDDDDDDDDDDDDDDMELLSAECDDFTTLSQLNEQQQALSAALKLPTTTAASSGGAATSQDDKLIDVDADVGGLPKPQHQSSLQNLLAGSDDKSQHLSDIDNESFNSIDFDAEITIAGSKEQQQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0009987 (cellular process), GO:0051641 (cellular localization), GO:0007163 (establishment or maintenance of cell polarity), GO:0022402 (cell cycle process), GO:0007049 (cell cycle), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0007017 (microtubule-based process), GO:0051640 (organelle localization), GO:0007018 (microtubule-based movement), GO:1903047 (mitotic cell cycle process), GO:0030010 (establishment of cell polarity), GO:0046907 (intracellular transport), GO:0051653 (spindle localization), GO:0051656 (establishment of organelle localization), GO:0006810 (transport), GO:0051649 (establishment of localization in cell), GO:0016043 (cellular component organization), GO:0000226 (microtubule cytoskeleton organization), GO:0051648 (vesicle localization), GO:0000278 (mitotic cell cycle), GO:1902850 (microtubule cytoskeleton organization involved in mitosis), GO:0010970 (transport along microtubule), GO:0097479 (synaptic vesicle localization), GO:0051293 (establishment of spindle localization), GO:0030705 (cytoskeleton-dependent intracellular transport), GO:0048489 (synaptic vesicle transport), GO:0051294 (establishment of spindle orientation), GO:0006996 (organelle organization), GO:0051650 (establishment of vesicle localization), GO:0099111 (microtubule-based transport), GO:0007010 (cytoskeleton organization), GO:0040001 (establishment of mitotic spindle localization), GO:0008088 (axo-dendritic transport), GO:0000132 (establishment of mitotic spindle orientation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Beta-centractin (Actin-related protein 1B) (ARP1B) (P42025)
Organism: Homo sapiens (Human)
Function: Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome.
Subcellular location: Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
InterPro domains:
- IPR043129: ATPase, nucleotide binding domain (homologous_superfamily) [9-376]
- IPR004000: Actin family (family) [9-376]
- IPR004001: Actin, conserved site (conserved_site) [357-365]
- IPR020902: Actin/actin-like conserved site (conserved_site) [109-121]
Sequence:
MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGPKAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVSRYLRLLLRKEGVDFHTSAEFEVVRTIKERACYLSINPQKDEALETEKVQYTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLFANIVLSGGSTLFKGFGDRLLSEVKKLAPKDIKIKISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGSRAIHRKTF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0016192 (vesicle-mediated transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005875 (microtubule associated complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0071944 (cell periphery), GO:0005615 (extracellular space), GO:0005737 (cytoplasm), GO:0005576 (extracellular region), GO:0043229 (intracellular organelle), GO:0005938 (cell cortex), GO:0099568 (cytoplasmic region), GO:0043230 (extracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0005813 (centrosome), GO:0005869 (dynactin complex), GO:0070062 (extracellular exosome), GO:0043227 (membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0099738 (cell cortex region), GO:1903561 (extracellular vesicle), GO:0005856 (cytoskeleton), GO:0015629 (actin cytoskeleton), GO:0015630 (microtubule cytoskeleton)
Protein: ELL-associated factor 2 (Testosterone-regulated apoptosis inducer and tumor suppressor protein) (Q96CJ1)
Organism: Homo sapiens (Human)
Function: Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity). Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo.
Subcellular location: Nucleus speckle {ECO:0000269|PubMed:12446457, ECO:0000269|PubMed:12907652}.
InterPro domains:
- IPR027093: EAF family (family) [1-260]
- IPR019194: Transcription elongation factor Eaf, N-terminal (domain) [17-113]
Sequence:
MNSAAGFSHLDRRERVLKLGESFEKQPRCAFHTVRYDFKPASIDTSSEGYLEVGEGEQVTITLPNIEGSTPPVTVFKGSKKPYLKECILIINHDTGECRLEKLSSNITVKKTRVEGSSKIQYRKEQQQQQMWNSARTPNLVKHSPSEDKMSPASPIDDIERELKAEASLMDQMSSCDSSSDSKSSSSSSSEDSSSDSEDEDCKSSTSDTGNCVSGHPTMTQYRIPDIDASHNRFRDNSGLLMNTLRNDLQLSESGSDSDD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0032784 (regulation of DNA-templated transcription elongation), GO:0034243 (regulation of transcription elongation by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0045171 (intercellular bridge), GO:0140513 (nuclear protein-containing complex), GO:0031974 (membrane-enclosed lumen), GO:0016604 (nuclear body), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0008023 (transcription elongation factor complex), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Beta-hexosaminidase subunit beta (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit beta) (N-acetyl-beta-glucosaminidase subunit beta) (F1QUU0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Cytoplasmic vesicle, secretory vesicle, Cortical granule {ECO:0000256|ARBA:ARBA00037865}. Lysosome {ECO:0000256|ARBA:ARBA00004371}.
InterPro domains:
- IPR025705: Beta-hexosaminidase (family) [4-463]
- IPR017853: Glycoside hydrolase superfamily (homologous_superfamily) [182-458]
- IPR029019: Beta-hexosaminidase, eukaryotic type, N-terminal (domain) [37-160]
- IPR015883: Glycoside hydrolase family 20, catalytic domain (domain) [182-447]
- IPR029018: Beta-hexosaminidase-like, domain 2 (homologous_superfamily) [33-181]
Sequence:
MLCLLKFTPLFLVVAVCHGWLFGDLFEKQKELDEISLWPLPQKYQSSAVAFKLSAASFQIVHAKQSTAGPSCSLLENAFRRYFEYMFGELKRQEKSRKKAFDSDLSELQVWITSADPECDGYPSLRTDESYSLSVDETSAVLKAANVWGALRGLETFSQLVYEDDYGVRNINKTDISDFPRFAHRGILLDSSRHFLPLKVILANLEAMAMNKFNVFHWHIVDDPSFPFMSRTFPELSQKGAYHPFTHVYTPSDVKMVIEFARMRGIRVVAEFDTPGHTQSWGNGIKDLLTPCYSGSSPSGSFGPVNPILNSSYEFMAQLFKEISTVFPDAYIHLGGDEVDFSCWKSNPDIQKFMNQQGFGTDYSKLESFYIQRLLDIVAATKKGYMVWQEVFDNGVKLKDDTVVEVWKGNDMKEELQNVTGAGFTTILSAPWYLDYISYGQDWQRYYKVEPLDFTGQFLQSNSF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds), GO:0015929 (hexosaminidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0035239 (tube morphogenesis), GO:0048514 (blood vessel morphogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Ribosomal RNA-processing protein 43 (Q381C6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
InterPro domains:
- IPR036345: Exoribonuclease, PH domain 2 superfamily (homologous_superfamily) [185-270]
- IPR050590: Exosome complex component Rrp42 subfamily (family) [17-269]
- IPR001247: Exoribonuclease, phosphorolytic domain 1 (domain) [68-169]
- IPR027408: PNPase/RNase PH domain superfamily (homologous_superfamily) [14-281]
- IPR020568: Ribosomal protein uS5 domain 2-type superfamily (homologous_superfamily) [18-218]
- IPR015847: Exoribonuclease, phosphorolytic domain 2 (domain) [190-247]
Sequence:
MSLPPATGAVELASFQQHVHQFLVQNKRLDGRPLDALREPHILRDSKGGDGLLASTLYTDNTGMCLNCTVSGVFGPPPSDQPDEGRLTVDVAAPFFQSHSTDQVAAALREVARFVRSTIISCMDLTELNIINGEACWVLQVELVILNADGGLRAAALHAVVAAIHNMLLPRSRLPNGDEVESRRLRFHTIPVAVTIGVYKLGASGVRFLMDTNAAEESVVDGLLTVVLSDENGIITFVQSGSYSISSLLLTGAVNEFALRSAALRAAILKPSVAAAKINGSKNSVTDPHPLKEG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0004518 (nuclease activity), GO:0004527 (exonuclease activity), GO:0008408 (3'-5' exonuclease activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0042254 (ribosome biogenesis), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0034470 (ncRNA processing), GO:0006364 (rRNA processing), GO:0034660 (ncRNA metabolic process), GO:0016072 (rRNA metabolic process), GO:0000460 (maturation of 5.8S rRNA)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0005622 (intracellular anatomical structure), GO:0000178 (exosome (RNase complex)), GO:1905354 (exoribonuclease complex)
Protein: DNA-directed RNA polymerase subunit Rpo1C (EC 2.7.7.6) (DNA-directed RNA polymerase subunit A'') (P58192)
Organism: Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
Function: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00411}.
InterPro domains:
- IPR007081: RNA polymerase Rpb1, domain 5 (domain) [23-338]
- IPR045867: DNA-directed RNA polymerase, subunit beta-prime (family) [31-385]
- IPR012757: DNA-directed RNA polymerase subunit Rpo1C (family) [6-390]
Sequence:
MIDEKDKPYLEEKVKQASNILPQKIVDDLKNLILNKEIIVTRDEIDKIFDLAIKEYSEGLIAPGEAIGIVAAQSVGEPGTQMTLRTFHFAGIRELNVTLGLPRLIEIVDAKKVPSTPMMTIYLTDEYKRDRDKALEVARKLEYTKIENVVSSTSIDIASMSIILQLDNEMLKDKGVTVDDVKKAIGRLKLGDFMIEESEDSTLNINFANIDSIAALFKLRDKILNTKIKGIKGIKRAIVQKKGDEYIILTDGSNLSGVLSVKGVDVAKVETNNIREIEEVFGIEAAREIIIREISKVLAEQGLDVDIRHILLIADVMTRTGIVRQIGRHGVTGEKNSVLARAAFEVTVKHLLDAAARGDVEEFKGVVENIIIGHPIKLGTGMVELTMRPILR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0090304 (nucleic acid metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0010467 (gene expression), GO:0018130 (heterocycle biosynthetic process), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:0016070 (RNA metabolic process), GO:0032774 (RNA biosynthetic process), GO:0097659 (nucleic acid-templated transcription), GO:0006351 (DNA-templated transcription), GO:0006366 (transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0140535 (intracellular protein-containing complex), GO:0030880 (RNA polymerase complex), GO:1990234 (transferase complex), GO:0000428 (DNA-directed RNA polymerase complex), GO:0061695 (transferase complex, transferring phosphorus-containing groups)
Protein: Cbb3-type cytochrome c oxidase subunit CcoN1 (EC 7.1.1.9) (Cytochrome CBB3 subunit CcoN1) (D9IA43)
Organism: Stutzerimonas stutzeri (Pseudomonas stutzeri)
Function: Cbb3-type cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits CcoN and CcoO form the functional core of the enzyme complex. Subunits CcoP and CcoQ may optionally bind to the core. CcoN is the catalytic subunit of the enzyme. Electrons originating in cytochrome c or a quinol are transferred to the bimetallic center formed by a high-spin heme and copper B. The complex also functions as a proton pump.
Subcellular location: Cell inner membrane {ECO:0000250|UniProtKB:P0ABI8}; Multi-pass membrane protein {ECO:0000255}.
InterPro domains:
- IPR000883: Cytochrome c oxidase subunit I (family) [9-463]
- IPR036927: Cytochrome c oxidase-like, subunit I superfamily (homologous_superfamily) [2-471]
- IPR004677: Cytochrome c oxidase cbb3-type, subunit I (family) [8-471]
- IPR023615: Cytochrome c oxidase, subunit I, copper-binding site (binding_site) [203-258]
- IPR023616: Cytochrome c oxidase-like, subunit I domain (domain) [1-474]
Sequence:
MNTATSTAYSYKVVRQFAIMTVVWGIVGMGLGVFIAAQLAWPFLNFDLPWTSFGRLRPLHTNAVIFAFGGCALFATSYYSVQRTCQTTLFAPKLAAFTFWGWQLVILLAAISLPLGFTSSKEYAELEWPIDILITIVWVAYAVVFFGTLAKRKVKHIYVGNWFFGAFILTVAILHVVNNLEIPVTAMKSYSLYAGATDAMVQWWYGHNAVGFFLTAGFLGIMYYFVPKQAERPVYSYRLSIVHFWALITVYIWAGPHHLHYTALPDWAQSLGMVMSLILLAPSWGGMINGMMTLSGAWHKLRSDPILRFLVVSLAFYGMSTFEGPMMAIKTVNALSHYTDWTIGHVHAGALGWVAMVSIGALYHLVPKVFGREQMHSIGLINTHFWLATIGTVLYIASMWVNGIAQGLMWRAINDDGTLTYSFVESLEASHPGFVVRMIGGAIFFAGMLVMAYNTWRTVQAAKPAEYDAAAQIA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016661 (oxidoreductase activity, acting on other nitrogenous compounds as donors), GO:0016662 (oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006091 (generation of precursor metabolites and energy), GO:0015980 (energy derivation by oxidation of organic compounds), GO:0022900 (electron transport chain), GO:0022904 (respiratory electron transport chain), GO:0045333 (cellular respiration), GO:0019646 (aerobic electron transport chain), GO:0009060 (aerobic respiration), GO:0042773 (ATP synthesis coupled electron transport), GO:0006123 (mitochondrial electron transport, cytochrome c to oxygen), GO:0042775 (mitochondrial ATP synthesis coupled electron transport), GO:0006119 (oxidative phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0070069 (cytochrome complex), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Kallikrein 4 (Kallikrein b1) (Kallikrein-related peptidase 4) (Q6IE12)
Organism: Rattus norvegicus (Rat)
Function: Not known
InterPro domains:
- IPR001314: Peptidase S1A, chymotrypsin family (family) [59-214]
- IPR043504: Peptidase S1, PA clan, chymotrypsin-like fold (homologous_superfamily) [44-249]
- IPR018114: Serine proteases, trypsin family, histidine active site (active_site) [69-74]
- IPR033116: Serine proteases, trypsin family, serine active site (active_site) [203-214]
- IPR009003: Peptidase S1, PA clan (homologous_superfamily) [18-254]
- IPR001254: Serine proteases, trypsin domain (domain) [31-254]
Sequence:
MMVTARTPWGWFLGYLILEVTGSSASSISSRIIQGQDCLPHSQPWQAALFSEDNAFFCSGVLVHPQWVLSAAHCIQDSYTVGLGLHNLEGSQEPGSRMLEAHLSIQHPNYNDPSFANDLMLIKLNESVMESNTIRRIPVASQCPTPGDTCLVSGWGRLKNGKLPSLLQCVNLSVASEETCRLLYDPVYHLSMFCAGGGPDRKDTCNGDSGGPIVCNRSLQGLVSMGQGECGQPGIPSVYTNLCKFTNWIWTTIQTR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0017171 (serine hydrolase activity), GO:0008233 (peptidase activity), GO:0008236 (serine-type peptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0044238 (primary metabolic process), GO:0009653 (anatomical structure morphogenesis), GO:0071704 (organic substance metabolic process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0009056 (catabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0016043 (cellular component organization), GO:0009887 (animal organ morphogenesis), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0097186 (amelogenesis), GO:1901575 (organic substance catabolic process), GO:0043170 (macromolecule metabolic process), GO:0048513 (animal organ development), GO:0009057 (macromolecule catabolic process), GO:0045229 (external encapsulating structure organization), GO:1901565 (organonitrogen compound catabolic process), GO:0043062 (extracellular structure organization), GO:0022411 (cellular component disassembly), GO:0030163 (protein catabolic process), GO:0042476 (odontogenesis), GO:0022617 (extracellular matrix disassembly), GO:0030198 (extracellular matrix organization), GO:0042475 (odontogenesis of dentin-containing tooth)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Nuclear speckle splicing regulatory protein 1 (Coiled-coil domain-containing protein 55) (A0A024QZ33)
Organism: Homo sapiens (Human)
Function: Not known
InterPro domains:
- IPR018612: Nuclear speckle splicing regulatory protein 1, N-terminal (domain) [5-123]
- IPR046850: Nuclear speckle splicing regulatory protein 1, RS-like domain (domain) [239-416]
- IPR042816: Nuclear speckle splicing regulatory protein 1 (family) [1-504]
Sequence:
MKQTKLEIQKALAEDATVYEYDSIYDEMQKKKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFVTSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSFREARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADDEIEETRVNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQSRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDREKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGVQSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTEEGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVNAKTYIEKEDD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0072359 (circulatory system development), GO:0007507 (heart development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)