lokahq/bioreason-rl huggingface dataset:
Protein: Retinitis pigmentosa 9 protein (Pim-1-associated protein) (PAP-1) (Q8TA86)
Organism: Homo sapiens (Human)
Function: Is thought to be a target protein for the PIM1 kinase. May play some roles in B-cell proliferation in association with PIM1 (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
InterPro domains:
- IPR034585: Retinitis pigmentosa 9 protein (family) [1-221]
Sequence:
MSSRPGREDVGAAGARRPREPPEQELQRRREQKRRRHDAQQLQQLKHLESFYEKPPPGLIKEDETKPEDCIPDVPGNEHAREFLAHAPTKGLWMPLGKEVKVMQCWRCKRYGHRTGDKECPFFIKGNQKLEQFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0019538 (protein metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0070647 (protein modification by small protein conjugation or removal), GO:0006396 (RNA processing), GO:0016570 (histone modification), GO:0034470 (ncRNA processing), GO:0032446 (protein modification by small protein conjugation), GO:0016574 (histone ubiquitination), GO:0034660 (ncRNA metabolic process), GO:0016180 (snRNA processing), GO:0016073 (snRNA metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0140534 (endoplasmic reticulum protein-containing complex), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0098796 (membrane protein complex), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0031090 (organelle membrane), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098827 (endoplasmic reticulum subcompartment), GO:0005791 (rough endoplasmic reticulum), GO:0043231 (intracellular membrane-bounded organelle), GO:0005789 (endoplasmic reticulum membrane), GO:0098588 (bounding membrane of organelle), GO:0030867 (rough endoplasmic reticulum membrane)
Protein: Dual specificity protein phosphatase 3 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase VHR) (Vaccinia H1-related phosphatase) (VHR) (P51452)
Organism: Homo sapiens (Human)
Function: Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2.
Subcellular location: Nucleus {ECO:0000269|PubMed:10224087, ECO:0000269|PubMed:27346674}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q9D7X3}.
InterPro domains:
- IPR029021: Protein-tyrosine phosphatase-like (homologous_superfamily) [3-185]
- IPR000387: Tyrosine-specific protein phosphatases domain (domain) [99-158]
- IPR020422: Dual specificity protein phosphatase domain (domain) [28-179]
- IPR020405: Atypical dual specificity phosphatase, subfamily A (family) [8-182]
- IPR016130: Protein-tyrosine phosphatase, active site (active_site) [122-132]
- IPR000340: Dual specificity phosphatase, catalytic domain (domain) [37-175]
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0004721 (phosphoprotein phosphatase activity), GO:0042802 (identical protein binding), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0046983 (protein dimerization activity), GO:0042803 (protein homodimerization activity), GO:0042578 (phosphoric ester hydrolase activity), GO:0008138 (protein tyrosine/serine/threonine phosphatase activity), GO:0016791 (phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0006793 (phosphorus metabolic process), GO:0036211 (protein modification process), GO:0006796 (phosphate-containing compound metabolic process), GO:0043412 (macromolecule modification), GO:0016311 (dephosphorylation), GO:0006470 (protein dephosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: WbcN protein (Q56917)
Organism: Yersinia enterocolitica
Function: Not known
InterPro domains:
- IPR028098: Glycosyltransferase subfamily 4-like, N-terminal domain (domain) [3-141]
- IPR001296: Glycosyl transferase, family 1 (domain) [151-319]
Sequence:
MYEAGHNVMIISLTGETLVRPNDGIQLNELKLDKAPFSLFKGLFEVKKIIKKFKPDIVHSHMFHANLFARILRVFTKIPALICTAHNTNEGSSLRMLAYKYTDKLASLSTNVSQDAVDSFIHKGASSTGRMIAVSNGIDASQFDFSMDERKVKRSELGIFNDTPIILSVGRLTEAKDYPNLLTAFSLLIKDNSLQSFPQLFIVGTGHLDGYLKNMSKEFGIDKYVTLFGQRDDILQLMCAADIFVLSSEWEGFPLVITEAMACKKIIVATDAGGITEALGDCGSIVPIKDPNSLSQAINKMIKLSDNEKEILGNKARERIIQTNSIEKIIELGCLFILNLKNNC
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016758 (hexosyltransferase activity), GO:0008194 (UDP-glycosyltransferase activity), GO:0035250 (UDP-galactosyltransferase activity), GO:0008378 (galactosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0005975 (carbohydrate metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0044262 (cellular carbohydrate metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:0016051 (carbohydrate biosynthetic process), GO:0005976 (polysaccharide metabolic process), GO:0034637 (cellular carbohydrate biosynthetic process), GO:1903509 (liposaccharide metabolic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0008653 (lipopolysaccharide metabolic process), GO:0044264 (cellular polysaccharide metabolic process), GO:0046379 (extracellular polysaccharide metabolic process), GO:0009103 (lipopolysaccharide biosynthetic process), GO:0033692 (cellular polysaccharide biosynthetic process), GO:0000271 (polysaccharide biosynthetic process), GO:0045226 (extracellular polysaccharide biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Protein S100-A3 (Protein S-100E) (S100 calcium-binding protein A3) (P33764)
Organism: Homo sapiens (Human)
Function: Binds both calcium and zinc. May be involved in calcium-dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18083705}.
InterPro domains:
- IPR011992: EF-hand domain pair (homologous_superfamily) [3-92]
- IPR034325: S-100 (domain) [4-90]
- IPR013787: S100/CaBP-9k-type, calcium binding, subdomain (domain) [5-47]
- IPR001751: S100/Calcium binding protein 7/8-like, conserved site (conserved_site) [58-79]
Sequence:
MARPLEQAVAAIVCTFQEYAGRCGDKYKLCQAELKELLQKELATWTPTEFRECDYNKFMSVLDTNKDCEVDFVEYVRSLACLCLYCHEYFKDCPSEPPCSQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0001501 (skeletal system development), GO:0060348 (bone development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0030312 (external encapsulating structure), GO:0005615 (extracellular space), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0031974 (membrane-enclosed lumen), GO:0012505 (endomembrane system), GO:0005576 (extracellular region), GO:0030141 (secretory granule), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0031012 (extracellular matrix), GO:0043230 (extracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043233 (organelle lumen), GO:0070062 (extracellular exosome), GO:0043227 (membrane-bounded organelle), GO:0060205 (cytoplasmic vesicle lumen), GO:0031983 (vesicle lumen), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0062023 (collagen-containing extracellular matrix), GO:0034774 (secretory granule lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031982 (vesicle), GO:1903561 (extracellular vesicle), GO:0097708 (intracellular vesicle), GO:0005634 (nucleus), GO:0005856 (cytoskeleton)
Protein: MA3 DOMAIN-CONTAINING TRANSLATION REGULATORY FACTOR 4 (MA3 domain-containing protein 7) (Q9STL9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in target of rapamycin (TOR)-regulated translation control, especially under energy-deficient conditions.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768}. Cytoplasm, cytosol {ECO:0000269|PubMed:29084871}.
InterPro domains:
- IPR016024: Armadillo-type fold (homologous_superfamily) [54-627]
- IPR003891: Initiation factor eIF-4 gamma, MA3 (domain) [56-633]
- IPR039778: Programmed cell death protein 4 (family) [28-627]
Sequence:
MATREWFVMNAQQTKLALESPPLFAVKKDDDKDHTCDTGEEPYALVGSPVFNPLEDYKREVVSIIDEYFSSGDVEVAASDLMDLGLSEYHPYFVKRLVSMAMDRGNKEKEKASVLLSRLYALVVSPDQIRVGFIRLLESVGDLALDIPDAVNVLALFIARAIVDEILPPVFLARAKKTLPHSSQGFQVILVSENSYLSAPHHAELVETKWGGSTHITVEETKRKISEFLNEYVENGDTREACRCIRELGVSFFHHEIVKSGLVLVMESRTSEPLILKLLKEATEEGLISSSQMAKGFSRVADSLDDLSLDIPSAKTLFESIVPKAIIGGWLDEDSFKERSDQNGGSENLRRFKKDAETIIQEYFLSDDIPELIRSLEDLGLPEYNPVFLKKLITLAMDRKNKEKEMASVFLASLHMEMFSTEDFINGFIMLLESAEDTALDILAASDELALFLARAVIDDVLAPLNLEEISNSLPPKSTGSETIRSARSLISARHAGERLLRSWGGGTGWAVEDAKDKIWKLLEEYEVGGVISEACRCIRDLGMPFFNHEVVKKALVMAMEKKNDRMLNLLQECFAEGIITTNQMTKGFGRVKDSLDDLSLDIPNAEEKFNSYVAHAEENGWLHRDFGCSTDS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0043021 (ribonucleoprotein complex binding), GO:0043022 (ribosome binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042594 (response to starvation), GO:0009991 (response to extracellular stimulus), GO:0009314 (response to radiation), GO:0009416 (response to light stimulus), GO:0031667 (response to nutrient levels), GO:0009642 (response to light intensity), GO:0009646 (response to absence of light)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Homeodomain-like transcriptional regulator (MYB transcription factor) (Putative I-box binding factor) (Similarity to Myb-related transcription factor) (Q9FIL9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
InterPro domains:
- IPR001005: SANT/Myb domain (domain) [30-189]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [33-190]
- IPR017930: Myb domain (domain) [135-191]
- IPR006447: Myb domain, plants (domain) [138-190]
- IPR017884: SANT domain (domain) [143-191]
Sequence:
MEVMRPSTSHVSGGNWLMEETKSGVAASGEGATWTAAENKAFENALAVYDDNTPDRWQKVAAVIPGKTVSDVIRQYNDLEADVSSIEAGLIPVPGYITSPPFTLDWAGGGGGCNGFKPGHQVCNKRSQAGRSPELERKKGVPWTEEEHKLFLMGLKKYGKGDWRNISRNFVITRTPTQVASHAQKYFIRQLSGGKDKRRASIHDITTVNLEEEASLETNKSSIVVGDQRSRLTAFPWNQTDNNGTQADAFNITIGNAISGVHSYGQVMIGGYNNADSCYDAQNTMFQL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0009755 (hormone-mediated signaling pathway), GO:0070887 (cellular response to chemical stimulus), GO:0071495 (cellular response to endogenous stimulus), GO:1901700 (response to oxygen-containing compound), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0009739 (response to gibberellin), GO:0032870 (cellular response to hormone stimulus), GO:0010476 (gibberellin mediated signaling pathway), GO:0071310 (cellular response to organic substance), GO:0033993 (response to lipid), GO:1901701 (cellular response to oxygen-containing compound), GO:0071370 (cellular response to gibberellin stimulus), GO:0009740 (gibberellic acid mediated signaling pathway), GO:0071396 (cellular response to lipid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: AT-hook motif nuclear-localized protein 16 (Protein TRANSPOSABLE ELEMENT SILENCING VIA AT-HOOK) (Protein TEK) (Q9SJG4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs). Encodes a nuclear matrix protein that acts in the maintenance of genomic integrity by silencing TEs and repeat-containing genes through epigenetic machinery. Acts as a chromatin remodeling factor that modifies the architecture of FLC and FWA chromatin by modulating both H3 acetylation and methylation leading to the regulation of FLC and FWA expression. Negatively regulates floral repressors including MAF4 and MAF5. Plays a transcription activation role in anther development. Regulates the expression of arabinogalactan proteins (AGPs) involved in the formation of the nexine layer of the pollen wall. Binds AGP6, AGP11, AGP23 and AGP40 promoters.
Subcellular location: Nucleus {ECO:0000269|PubMed:24804694}.
InterPro domains:
- IPR014476: AT-hook motif nuclear-localized protein 15-29 (family) [1-257]
- IPR005175: PPC domain (domain) [77-214]
Sequence:
MAGGTALTPTSVGSKSVPMRNHEATERGNTNNNLRALPKAVQPVSSIEGEMAKRPRGRPAGSKNKPKPPIIVTHDSPNSLRANAVEISSGCDICETLSDFARRKQRGLCILSANGCVTNVTLRQPASSGAIVTLHGRYEILSLLGSILPPPAPLGITGLTIYLAGPQGQVVGGGVVGGLIASGPVVLMAASFMNAVFDRLPMDDDEAASMQNQQYYQNGRSRPLDDIHGLPQNLLTNGNSASDIYSWGPAQRVMSKP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0043621 (protein self-association)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0002682 (regulation of immune system process), GO:0002683 (negative regulation of immune system process), GO:0048585 (negative regulation of response to stimulus), GO:0050777 (negative regulation of immune response), GO:0032101 (regulation of response to external stimulus), GO:0002831 (regulation of response to biotic stimulus), GO:0050776 (regulation of immune response), GO:0002832 (negative regulation of response to biotic stimulus), GO:0080134 (regulation of response to stress), GO:0031348 (negative regulation of defense response), GO:0032102 (negative regulation of response to external stimulus), GO:0031347 (regulation of defense response), GO:0045824 (negative regulation of innate immune response), GO:0045088 (regulation of innate immune response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Protein OS-9 homolog (AtOS9) (Protein EMS-MUTAGENIZED BRI1 SUPPRESSOR 6) (Q8GWH3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Targets the misfolded LRR receptor kinase BRI1 and the misfolded receptor-like kinase EFR.
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:22328055, ECO:0000269|PubMed:22516478}.
InterPro domains:
- IPR044865: MRH domain (domain) [120-239]
- IPR009011: Mannose-6-phosphate receptor binding domain superfamily (homologous_superfamily) [118-238]
- IPR012913: Protein OS9-like domain (domain) [121-194]
- IPR045149: Protein OS-9-like (family) [8-270]
Sequence:
MRITQILLCLVIVALSSSSHVWSDQIFPAHLVGTFSRNNREPKYKIEFLPEDSPFHPGDNLESMVMLDKHGNRFLCYLPKEEKATSGWTSSQQNISTVMMETQQLVKLKTPDELLQPLSEKCLFRQEGWWSYEFCHQKYVRQLHVEDENKIVQEFFLGTFDPEATAAFNQTVSDASTDASQRYHSHVYTNGTTCDLTGSPREVEVRFVCAETRAMVTSITELSTCKYALTVQCPTLCKHPLFQLEKPVSHTIHCNAIPVEEDATRNKEEQAVDESPKMIADS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0008380 (RNA splicing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)