lokahq/bioreason-rl huggingface dataset:
Protein: 5'-nucleotidase, cytosolic IA (A0A8I5ZYY7)
Organism: Rattus norvegicus (Rat)
Function: Not known
InterPro domains:
- IPR010394: 5-nucleotidase (family) [39-360]
Sequence:
MTISRPRRNPNRPWLILVTEIVSCGLPVSGVWSVPTEAPEMVDSQPKPQNAVTIAVSSRALFRMDEEQRIYTEQGVEEYVRYQLEHENEPFSPGPAFPFVKALEAVNKQLRELYPDSEDIFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADAEKVREAIDEGIAAATIFSPSKDVVVSQSQLRVAFDGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQNPRREKQSLGAQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0016791 (phosphatase activity), GO:0008252 (nucleotidase activity), GO:0008253 (5'-nucleotidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:1901657 (glycosyl compound metabolic process), GO:0072521 (purine-containing compound metabolic process), GO:0009116 (nucleoside metabolic process), GO:0009119 (ribonucleoside metabolic process), GO:0042278 (purine nucleoside metabolic process), GO:0046128 (purine ribonucleoside metabolic process), GO:0046085 (adenosine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Membrane associated ring-CH-type finger 1 (D6REN1)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000256|ARBA:ARBA00004439}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004439}. Early endosome membrane {ECO:0000256|ARBA:ARBA00004520}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004520}. Lysosome membrane {ECO:0000256|ARBA:ARBA00004155}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004155}.
InterPro domains:
- IPR011016: Zinc finger, RING-CH-type (domain) [72-133]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [65-140]
- IPR001841: Zinc finger, RING-type (domain) [80-127]
Sequence:
MLGWCEAIARNPHRIPNNTRTPEISGDLADASQTSTLNEKSPGRSASRSSNISKASSPTTGTAPRSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFIMETKLKPLRK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity), GO:0061659 (ubiquitin-like protein ligase activity), GO:0061630 (ubiquitin protein ligase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044248 (cellular catabolic process), GO:0019538 (protein metabolic process), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0036211 (protein modification process), GO:0009057 (macromolecule catabolic process), GO:0043412 (macromolecule modification), GO:1901565 (organonitrogen compound catabolic process), GO:0006508 (proteolysis), GO:0044265 (cellular macromolecule catabolic process), GO:0030163 (protein catabolic process), GO:0070647 (protein modification by small protein conjugation or removal), GO:0043632 (modification-dependent macromolecule catabolic process), GO:0051603 (proteolysis involved in protein catabolic process), GO:0032446 (protein modification by small protein conjugation), GO:0019941 (modification-dependent protein catabolic process), GO:0016567 (protein ubiquitination), GO:0006511 (ubiquitin-dependent protein catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Palmitoyltransferase (EC 2.3.1.225) (Q0IGS7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
InterPro domains:
- IPR001594: Palmitoyltransferase, DHHC domain (domain) [96-231]
- IPR039859: Palmitoyltransferase PFA4/ZDHHC16/ZDHHC20/ERF2-like (family) [19-276]
Sequence:
MMILRSWDRVKPRSISDFACFLLVAVFVPVTYIFHVTIVMPELFAIGGIWYTLLWLASLFLIFNITSNMLACMLVDTSIRKELLKPPLDAAQLARWHSCQDCQTLVPPRSWHCEVCNVCVLKRDHHCRFTCCCIGHHNYRYFFYYLVYMIIGSLAAAIMESIYLWHLHLDIYWRWSTLFTIFAPVVSLMLSPSWESFYLVIYDLTLLGFAISSLLLVFHWSIFKSGSVTRERGTRKYDRGLRGNLEMVLGKRMHLTWLSPFLRSDLPHDGMNWEPIAAFSPKEE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016746 (acyltransferase activity), GO:0019707 (protein-cysteine S-acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0019706 (protein-cysteine S-palmitoyltransferase activity), GO:0016417 (S-acyltransferase activity), GO:0016409 (palmitoyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009615 (response to virus), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0140546 (defense response to symbiont), GO:0051607 (defense response to virus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: SPX domain-containing protein 3 (Protein SPX DOMAIN GENE 3) (OsSPX3) (Q7XEY9)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Functional repressor of PHR2. Involved in maintaining cellular Pi homeostasis when plants are exposed to an external change in Pi. Negatively regulates root-to-shoot Pi translocation redundantly with SPX3. Down-regulates the non-coding RNA IPS1 (At3g09922) and suppresses the responses of miR399 and PHO2 to Pi-starvation.
Subcellular location: Nucleus {ECO:0000269|PubMed:24368504}. Cytoplasm {ECO:0000269|PubMed:19566645, ECO:0000269|PubMed:24368504}.
InterPro domains:
- IPR031142: SPX domain-containing protein (family) [1-245]
- IPR004331: SPX domain (domain) [1-154]
Sequence:
MKFGKRLKKQVEESLPEWRDKFLAYKRLKKLVRLVSSSSGDVGGGGGGEAEFVRLLDGEVDRINAFFLEQEEEFVIRQRELQETVEKVAGGGGGGRRPAAAEMRRVRKEIVDLHGEMVLLLNYSAVNYTGLAKILKKYDKRTGRLLRLPFIEKVLRQPFFTTELISRLVRDCEATMEAIFTSSVATTAMAGDRRTWKGCSGDAGMAPMADQQGIFRNTVAALATMKELRSGSSTYGRFSLPPMAAPASPESDVLQSIRSDPHLKENGRIPSLQFFYA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0009266 (response to temperature stimulus), GO:0009409 (response to cold), GO:0033554 (cellular response to stress), GO:0070417 (cellular response to cold)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: UPF0381 protein YfcZ (P0AD33)
Organism: Escherichia coli (strain K12)
Function: Not known
InterPro domains:
- IPR035571: UPF0234-like, C-terminal (homologous_superfamily) [2-94]
- IPR005272: Protein of unknown function DUF406 (family) [1-94]
Sequence:
MSKCSADETPVCCCMDVGTIMDNSDCTASYSRVFANRAEAEQTLAALTEKARSVESEPCKITPTFTEESDGVRLDIDFTFACEAEMLIFQLGLR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0006950 (response to stress), GO:0009628 (response to abiotic stimulus), GO:0009408 (response to heat), GO:0009266 (response to temperature stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Hemogen (Erythroid differentiation-associated gene protein) (EDAG-1) (Hemopoietic gene protein) (Negative differentiation regulator protein) (Q9BXL5)
Organism: Homo sapiens (Human)
Function: Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB).
Subcellular location: Nucleus {ECO:0000269|PubMed:14730214}.
InterPro domains:
- IPR033272: Hemogen (family) [1-484]
Sequence:
MDLGKDQSHLKHHQTPDPHQEENHSPEVIGTWSLRNRELLRKRKAEVHEKETSQWLFGEQKKRKQQRTGKGNRRGRKRQQNTELKVEPQPQIEKEIVEKALAPIEKKTEPPGSITKVFPSVASPQKVVPEEHFSEICQESNIYQENFSEYQEIAVQNHSSETCQHVSEPEDLSPKMYQEISVLQDNSSKICQDMKEPEDNSPNTCQVISVIQDHPFKMYQDMAKREDLAPKMCQEAAVPKILPCPTSEDTADLAGCSLQAYPKPDVPKGYILDTDQNPAEPEEYNETDQGIAETEGLFPKIQEIAEPKDLSTKTHQESAEPKYLPHKTCNEIIVPKAPSHKTIQETPHSEDYSIEINQETPGSEKYSPETYQEIPGLEEYSPEIYQETSQLEEYSPEIYQETPGPEDLSTETYKNKDVPKECFPEPHQETGGPQGQDPKAHQEDAKDAYTFPQEMKEKPKEEPGIPAILNESHPENDVYSYVLF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050793 (regulation of developmental process), GO:0050794 (regulation of cellular process), GO:0045595 (regulation of cell differentiation), GO:0045667 (regulation of osteoblast differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Adenylate dimethylallyltransferase (EC 2.5.1.27) (Isopentenyl transferase) (Q86K86)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Transfers dimethylallyl groups to AMP as part of the biosynthesis of cytokinin phytohormones like isopentenyl adenine or discadenine which controle spore formation and viability.
InterPro domains:
- IPR002648: Adenylate dimethylallyltransferase (family) [1-281]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [1-281]
Sequence:
MKILLIIGSTGVGKTDLSINYSKKYNAPVVVLDRIQCFPELSITSGRPDESEYFGSKRIYLTDLLVEPGNENIKKTFYVNKLINILNEIKNNYDTQNLPNEKGYGCIFEGGSISLLKELLTKINKLPYKITCVIYIRPSDSIDNHKLYKAKIFKRVSQMLFPTEEGNDSQILEVKRILNKGKTVNAQGEINLEYYEKIKQVLISLVGLVGIEDVIHFLDKQYDQKNITSKLDPNYLNEIQSQLIETITLAHYNYALSQIELIDSLIKQLPKSIEYCLKNIEIN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0042445 (hormone metabolic process), GO:0065008 (regulation of biological quality), GO:0071840 (cellular component organization or biogenesis), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:0016043 (cellular component organization), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0010817 (regulation of hormone levels), GO:0009690 (cytokinin metabolic process), GO:0046483 (heterocycle metabolic process), GO:0009308 (amine metabolic process), GO:0018958 (phenol-containing compound metabolic process), GO:0043933 (protein-containing complex organization), GO:0018958 (phenol-containing compound metabolic process), GO:0065003 (protein-containing complex assembly), GO:0009712 (catechol-containing compound metabolic process), GO:0006576 (biogenic amine metabolic process), GO:0006584 (catecholamine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0030139 (endocytic vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle), GO:0045335 (phagocytic vesicle)
Protein: DNA-directed RNA polymerase subunit alpha (RNAP subunit alpha) (EC 2.7.7.6) (RNA polymerase subunit alpha) (Transcriptase subunit alpha) (P20429)
Organism: Bacillus subtilis (strain 168)
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
InterPro domains:
- IPR011260: RNA polymerase, alpha subunit, C-terminal (domain) [240-305]
- IPR036603: RNA polymerase, RBP11-like subunit (homologous_superfamily) [5-230]
- IPR011262: DNA-directed RNA polymerase, insert domain (domain) [56-171]
- IPR011263: DNA-directed RNA polymerase, RpoA/D/Rpb3-type (domain) [20-227]
- IPR011773: DNA-directed RNA polymerase, alpha subunit (family) [1-313]
- IPR036643: DNA-directed RNA polymerase, insert domain superfamily (homologous_superfamily) [50-171]
Sequence:
MIEIEKPKIETVEISDDAKFGKFVVEPLERGYGTTLGNSLRRILLSSLPGAAVTSIQIDGVLHEFSTIEGVVEDVTTIILHIKKLALKIYSDEEKTLEIDVQGEGTVTAADITHDSDVEILNPDLHIATLGENASFRVRLTAQRGRGYTPADANKRDDQPIGVIPIDSIYTPVSRVSYQVENTRVGQVANYDKLTLDVWTDGSTGPKEAIALGSKILTEHLNIFVGLTDEAQHAEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVQELANKTEEDMMKVRNLGRKSLEEVKAKLEELGLGLRKDD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0090304 (nucleic acid metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0010467 (gene expression), GO:0018130 (heterocycle biosynthetic process), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:0016070 (RNA metabolic process), GO:0032774 (RNA biosynthetic process), GO:0097659 (nucleic acid-templated transcription), GO:0006351 (DNA-templated transcription), GO:0006366 (transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0140535 (intracellular protein-containing complex), GO:0030880 (RNA polymerase complex), GO:1990234 (transferase complex), GO:0000428 (DNA-directed RNA polymerase complex), GO:0061695 (transferase complex, transferring phosphorus-containing groups)
Protein: Rifin (Q8I2C8)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Not known
InterPro domains:
- IPR006373: Variant surface antigen Rifin (family) [1-368]
Sequence:
MKDHYINILLFALPLNILVYNQRNYYITPRHTETNRSLCECELYSPTNYDSDPEMKRVMQQFEDRTTQRFHEYDEKMQSKRIQCKDRCDKEIQKIILKDKLDKELTEKFATLHTDIQNDAIPTCVCEKSLADKVEKTCLKCTQNLGGIVAPSSGVLGGIGEFELSVWKPAALAAAKEFAEKAGAAQGAIAGNAHGMKIVIYYLKDWGIQQCCPEIFNPFVAKNIYTEVANISGDIIAKYSAKCADTVTGGNSMCKAFCLKLGTNIAHGGRTLSVDHIVQLKIKGLVERADQAVAHVTKTTSETVTAAIKARETALIEGRFESSITSINASIIAIIVIVLILVIIYLILRYRRKKKMKKKLQYLKLLKE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0046812 (host cell surface binding), GO:0046789 (host cell surface receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response), GO:0042783 (evasion of host immune response), GO:0020033 (antigenic variation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0033643 (host cell part), GO:0043657 (host cell), GO:0033644 (host cell membrane), GO:0020002 (host cell plasma membrane)
Protein: Receptor homology region, transmembrane domain- and RING domain-containing protein 2 (AtRMR2) (ReMembR-H2 protein JR702) (Q8VZ14)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the trafficking of vacuolar proteins. May function as a sorting receptor for protein trafficking to the protein storage vacuole (PSV) (By similarity).
Subcellular location: Protein storage vacuole membrane {ECO:0000269|PubMed:10953001}. Golgi apparatus membrane {ECO:0000305|PubMed:10953001}; Single-pass type I membrane protein {ECO:0000305|PubMed:10953001}. Note=Traffics through the Golgi apparatus before reaching the vacuolar compartment.
InterPro domains:
- IPR051653: E3 ubiquitin-protein ligase and sorting receptor (family) [19-289]
- IPR046450: PA domain superfamily (homologous_superfamily) [31-162]
- IPR044744: ZNRF4 /RNF13/RNF167, PA domain (domain) [11-161]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [191-279]
- IPR003137: PA domain (domain) [52-140]
- IPR001841: Zinc finger, RING-type (domain) [231-274]
Sequence:
MNRALVLLLYVCTVSCLASSKVILMRNNITLSFDDIEANFAPSVKGTGEIGVVYVAEPLDACQNLMNKPEQSSNETSPFVLIVRGGCSFEEKVRKAQRAGFKAAIIYDNEDRGTLIAMAGNSGGIRIHAVFVTKETGEVLKEYAGFPDTKVWLIPSFENSAWSIMAVSFISLLAMSAVLATCFFVRRHRIRRRTSRSSRVREFHGMSRRLVKAMPSLIFSSFHEDNTTAFTCAICLEDYTVGDKLRLLPCCHKFHAACVDSWLTSWRTFCPVCKRDARTSTGEPPASESTPLLSSAASSFTSSSLHSSVRSSALLIGPSLGSLPTSISFSPAYASSSYIRQSFQSSSNRRSPPISVSRSSVDLRQQAASPSPSPSQRSYISHMASPQSLGYPTISPFNTRYMSPYRPSPSNASPAMAGSSNYPLNPLRYSESAGTFSPYASANSLPDC
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0001666 (response to hypoxia), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0070482 (response to oxygen levels), GO:0071456 (cellular response to hypoxia), GO:0071453 (cellular response to oxygen levels), GO:0036293 (response to decreased oxygen levels), GO:0036294 (cellular response to decreased oxygen levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0005794 (Golgi apparatus), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0098791 (Golgi apparatus subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0005802 (trans-Golgi network), GO:0097708 (intracellular vesicle)