Protein: Beta-selinene synthase (EC 4.2.3.66) (Terpene synthase 21) (ZmTps21) (A0A291LSD6)
Organism: Zea mays (Maize)
Function: Sesquiterpene cyclase that converts farnesyl diphosphate to the volatile beta-selinene and the corresponding nonvolatile antibiotic derivative beta-costic acid, especially in roots upon infection by rootworm larvae (D.balteata) and fungal pathogens (e.g. Fusarium spp.).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q6Q3H2}.
InterPro domains:
- IPR008930: Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid (homologous_superfamily) [38-245]
- IPR005630: Terpene synthase, metal-binding domain (domain) [277-513]
- IPR001906: Terpene synthase, N-terminal domain (domain) [40-219]
- IPR008949: Isoprenoid synthase domain superfamily (homologous_superfamily) [38-569]
- IPR034741: Terpene cyclase-like 1, C-terminal domain (domain) [247-570]
- IPR050148: Terpene synthase-like (family) [36-552]
- IPR044814: Terpene cyclases, class 1, plant (family) [34-569]
- IPR036965: Terpene synthase, N-terminal domain superfamily (homologous_superfamily) [83-245]
Sequence:
MDGDIAAALPPVNQQSKADGTAVAAAAAAAACHGDFEPSVWGDFFVTYTSPPSLSQEPEEQMRERANFLKGEVRKKFEAAAAMSAINSAMLVDAVVHLGIDHCFREEIATALRSVHKEEGEFGSCDDLHTVAVRFLVLRQHGLWVSADVFDKFRDDTGSLSKSLLCSNPRGLLSLYNAAHMVTPEEKVLDDAIAFARSHLEAMIGELRSPMVEQVSRSLDIPLPRFSRRLESMHYIAEYGQEEGHDAQILELARLEFELVRSLHLRELREICRWWRELYNDVKLPYARDRIVEIYFWACGVIHEEEMSRARMIFAKTFAFTSLIDDTCDVHATLEEVQKFNEAMQSWEEDAVSIVPEYLRTLYSRTIKGFQEFEDMLEPNEKYSMSYVKKAYKLLLQYYLKEATWANENHTPSFKEHVQVSIISSGLPMLVPVLLMGTGLATREAFEWADSAPDMVLASGEVGRFLNDMASYKLGKNKKDVANAHECYMKEYGATGEEAFAFIANMTENAWRKINQACMEMDPAMLPAFKVAVVDLSRSMEIIYLGGKRDAYTFGSNLKDLVTSLFLKPCA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016835 (carbon-oxygen lyase activity), GO:0016838 (carbon-oxygen lyase activity, acting on phosphates), GO:0010333 (terpene synthase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0009058 (biosynthetic process), GO:0006950 (response to stress), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0044238 (primary metabolic process), GO:0006952 (defense response), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901576 (organic substance biosynthetic process), GO:0043207 (response to external biotic stimulus), GO:0006629 (lipid metabolic process), GO:0009620 (response to fungus), GO:0098542 (defense response to other organism), GO:0006720 (isoprenoid metabolic process), GO:0008299 (isoprenoid biosynthetic process), GO:0050832 (defense response to fungus), GO:0008610 (lipid biosynthetic process), GO:0006721 (terpenoid metabolic process), GO:0016114 (terpenoid biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0005773 (vacuole), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000325 (plant-type vacuole), GO:0043231 (intracellular membrane-bounded organelle)