lokahq/bioreason-rl huggingface dataset:
Protein: Splicing factor ESS-2 (ES2 similar protein 2) (P34420)
Organism: Caenorhabditis elegans
Function: Regulates pre-mRNA splicing.
Subcellular location: Nucleus {ECO:0000269|PubMed:25194163}.
InterPro domains:
- IPR019148: Nuclear protein DGCR14/ESS-2 (family) [13-488]
Sequence:
MSSFDKNDERAQLMVPKSINEGKVVKLSQKTLVTKKIERQVVPEEKYIAGLDKIIEKDYFPHLKKMQAQKEYLEAVANKDINKIKELQMKFCSTGSVRTDRSFRTPITTRSTTEAPDVSSFDADTPGPSSASTSSAHDWMQSPMPFANEEGDNEALNRKRKKKKEETLTSYLNKYTSEDNASFEELAKVMREREDARRPWVYKAEEEHNKNLVTRQAIAAEADVQLALKHAVDADDNRPLNVDNWAYKAWNTVLFNPDGAALTPAEIADAARKQQTEINKRGTRFPDSGKLKPSDEAMTRAAVSHALANAGKVDFLGNEVTPANSFKLLETPNPNPDDMDSPLMTWGEIDGTPFRLDAPDVTEHSLPGAAPVFKIPEVPYREKIAQSMNDSIAAKYRDKRKVAMRAAEGAHFSRTPGFGSKRVSDKLAQLSPAAQKLATKKLGLKMLPAHKSPFASPKIMSNWSRPSSSKRSTTPGSAWSRGSTTPGSSWSQGAQTPGTPGIESMIRRKGDNVGPSTSAGAADRANAGDFF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0032502 (developmental process), GO:0007275 (multicellular organism development), GO:0048856 (anatomical structure development), GO:0009790 (embryo development), GO:0009792 (embryo development ending in birth or egg hatching)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Growth-regulating factor 1 (AtGRF1) (Transcription activator GRF1) (O81001)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. microRNA396-GRF1/GRF3 regulatory module acts as a developmental regulator in the reprogramming of root cells during cyst nematode infection, leading to the formation of the syncytium.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU01002}.
InterPro domains:
- IPR014978: Glutamine-Leucine-Glutamine, QLQ (domain) [132-168]
- IPR031137: Growth-regulating factor (family) [82-404]
- IPR014977: WRC domain (domain) [196-240]
Sequence:
MDLGVRVSGHETVSSPGQTELGSGFSNKQERSGFDGEDCWRSSKLSRTSTDGFSSSPASAKTLSFHQGIPLLRSTTINDPRKGQEHMLSFSSASGKSDVSPYLQYCRNSGYGLGGMMNTSNMHGNLLTGVKGPFSLTQWAELEQQALIYKYITANVPVPSSLLLSLKKSFFPYGSLPPNSFGWGSFHLGFSGGNMDPEPGRCRRTDGKKWRCSRDAVPDQKYCERHINRGRHRSRKPVEGQNGHNTNAAAAASAAAASTAAAVSKAAAGTSAVAMRGSDNNNSLAAAVGTQHHTNNQSTDSLANRVQNSRGASVFPATMNLQSKETHPKQSNNPFEFGLISSDSLLNPSHKQASYATSSKGFGSYLDFGNQAKHAGNHNNVDSWPEELKSDWTQLSMSIPMAPSSPVQDKLALSPLRLSREFDPAIHMGLGVNTEFLDPGKKTNNWIPISWGNNNSMGGPLGEVLNSTTNSPKFGSSPTGVLQKSTFGSLSNSSSASSTIIGDNNNKNGDGKDPLGPTTLMNTSATAPSL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0065007 (biological regulation), GO:0032501 (multicellular organismal process), GO:0048523 (negative regulation of cellular process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0050794 (regulation of cellular process), GO:0099402 (plant organ development), GO:0048731 (system development), GO:0008285 (negative regulation of cell population proliferation), GO:0042127 (regulation of cell population proliferation), GO:0048364 (root development), GO:0022622 (root system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Ribosome biogenesis protein NOP53 (Q9NEU5)
Organism: Caenorhabditis elegans
Function: May play a role in ribosome biogenesis, being required for integration of the 5S RNP into the ribosomal large subunit.
Subcellular location: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9NZM5}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q9NZM5}.
InterPro domains:
- IPR011687: Ribosome biogenesis protein Nop53/GLTSCR2 (family) [1-438]
Sequence:
MVAGKRTGAAKGSRHNKKYWRKGTNIDDIEDSIHIKSRQAATGGVISEMKDEDLFIVDRTATANKPVVPKLTKKQQAALEKITKNITQEHVTLPKPSTTSKILKKPAKLPRGNAILALKKGPKAAAPAAKKKNFDVWTTDLTPKIPKSKLENQEAAEHFLKVVKKKQPKTPGKSITSLLPAVQIAEGGASYNPESAEYQEYVAKIAGEEQKLIDHEAKIKAGIEPQWEKVTTEHERFLEMAEGLRIHPKYGKDDEEEEEAGNSEKSMKTGGEAEPKSQRVECDRMTKEQKKKKAKAQKLDKEEKRRLEEKAKEQDSHNVYRTKQLHKELDEEEKQRHEESEVRKKEKLINKLTKRQQLGKGKFVDAEDPFLLQEELTGNLRQLKPQGHVLDDRMKSLQRRNMLPIGGDKEKRRIKNRLKSKVVEKRSAKNIVKGSRVI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0019843 (rRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0032502 (developmental process), GO:0007275 (multicellular organism development), GO:0048856 (anatomical structure development), GO:0009790 (embryo development), GO:0009792 (embryo development ending in birth or egg hatching)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005634 (nucleus)
Protein: DNA-directed RNA polymerase (EC 2.7.7.6) (Plastid-encoded RNA polymerase subunit alpha) (Q2LIP1)
Organism: Oryza punctata (Red rice)
Function: Not known
Subcellular location: Plastid, chloroplast {ECO:0000256|ARBA:ARBA00004229}.
InterPro domains:
- IPR011260: RNA polymerase, alpha subunit, C-terminal (domain) [247-305]
- IPR036603: RNA polymerase, RBP11-like subunit (homologous_superfamily) [2-211]
- IPR011262: DNA-directed RNA polymerase, insert domain (domain) [48-155]
- IPR011263: DNA-directed RNA polymerase, RpoA/D/Rpb3-type (domain) [9-212]
- IPR011773: DNA-directed RNA polymerase, alpha subunit (family) [4-315]
- IPR036643: DNA-directed RNA polymerase, insert domain superfamily (homologous_superfamily) [39-156]
Sequence:
RVDSKRLYYGRFILSPLRKGQADTVGIALRRALLGETEGTCITHAKFGSVPHEYSTIAGIEESVQEILLNLKEIVLRSNLYGVRNASICVKGPRYITAQDIILPPSVEIVDTAQPIANLTEPEDFRIELRIKRDRGYHTEVRKNTQDGSYPIDAVSMPVRNVNYSIFSCGNGNAKYEILFLEIWTNGSLTPKEALYEASRNLIDLFLPFLHTEEEGTRFQENKNRFTSPLLSFQKRLTNLKKNKKRIPLNCIFIDQLELPSRTYNCLKRANIHTLLDLLSKTEEDLMRIDSFRMQDGKQIWDTLEKHLPMDLPKNKF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0090304 (nucleic acid metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0010467 (gene expression), GO:0018130 (heterocycle biosynthetic process), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:0016070 (RNA metabolic process), GO:0032774 (RNA biosynthetic process), GO:0097659 (nucleic acid-templated transcription), GO:0006351 (DNA-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Syntaxin 16 (A0A0G2K528)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004409}; Single-pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004409}.
InterPro domains:
- IPR045242: Syntaxin (family) [92-312]
- IPR000727: Target SNARE coiled-coil homology domain (domain) [226-319]
- IPR010989: SNARE (homologous_superfamily) [74-286]
- IPR006012: Syntaxin/epimorphin, conserved site (conserved_site) [237-276]
Sequence:
MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHTTSSPLHSRSIAAELDELADDRMALVSGISLDPEAAIGVTKRSPPKWVDGVDEIQYDVGRIKQKMRELASLHDKHLNRPTLDDSSEEEHAIEITTQEVTQLFHRCQRAVQALPSRARRTCSEQEERLLRNVVASLAQALQELSTSFRHAQSDYLKRMKNREERSQHFFDTPVPLMDDGDDATLYGQGFTDDQLVLVEQNTLVVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCVKTEDGLKQLHKAEQYQKKNRKMLVILILVAVIVVLIVVLIAVKSR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0051649 (establishment of localization in cell), GO:0046907 (intracellular transport), GO:0051668 (localization within membrane), GO:0006810 (transport), GO:0016482 (cytosolic transport), GO:0016192 (vesicle-mediated transport), GO:0016197 (endosomal transport), GO:0098876 (vesicle-mediated transport to the plasma membrane), GO:0032456 (endocytic recycling), GO:0042147 (retrograde transport, endosome to Golgi)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0098793 (presynapse), GO:0098796 (membrane protein complex), GO:0030054 (cell junction), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0031201 (SNARE complex), GO:0008021 (synaptic vesicle), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0030133 (transport vesicle), GO:0043227 (membrane-bounded organelle), GO:0030658 (transport vesicle membrane), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0012506 (vesicle membrane), GO:0070382 (exocytic vesicle), GO:0030672 (synaptic vesicle membrane), GO:0031982 (vesicle), GO:0030659 (cytoplasmic vesicle membrane), GO:0097708 (intracellular vesicle), GO:0099501 (exocytic vesicle membrane)
Protein: C3H1-type domain-containing protein (Q57Y78)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
InterPro domains:
- IPR000571: Zinc finger, CCCH-type (domain) [292-411]
- IPR053125: RNA-binding mRNA stabilization regulator (family) [83-686]
Sequence:
MFLPEQSNIPGSVTYVSRAAGIPSSSTTQQYQGGECMGVPSELDAIDGGCAWRTASKGVCASQLPRGGSVAVSVSAPFIHLTDWGDATVSTREISDNAAEVPAARSIGNREGVDGSLTSSVFPSGDVNSTIDLPISLVNSALPNQEKNNMEFQDDCLAHVFSRPESPFKDFSAESEDPFTIMQTRSVTCNPNIWEVEGKDVQSSLIHDAVKVGMSQITPSLFSPITEAMESAIDKVKVAPDGLNDCRTVGPQQPTEEQRIPVVDPQRSKLHVPLSSIIPTKALGGRVSFPSLCLLFQSGRCLRGASCYQMHIDPQVVQRLRQINESLPYCCAFHGECNANKWDAEANAHRTILIKGAAVPLSRVAYTNGLERFVLKNNASRSLNTCAVCRLHGKPGGCRYGADCWYVHICRDVLKELVATIKLDLEDPGSEDQCKVPTKTESTGNRVVSGDLLGALSQQQNRRKQQNYPTVAFHPSKSPTMSHLHKGRSIVSSERDGTHSGKLSSHGSASTNTFSARASPTVGQITSDGTTCRNVLVQQRPPVYEDGPLGETRHGLATTMRLHGVAFPVTDPSEEKSVPSPSQFSLNDRQSVTPISGREVSTPSVPCCAMYFPQKQSSVAPCPQPMQNGHTVWPSTVLVPSTTVMYPMISATGLPVASAQQQMGTDGQTYGPFCFVSGREDGFRNLCLPMYGSGKGNMPSQVPLHVPF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010468 (regulation of gene expression), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Interleukin-22 (Q198B4)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
InterPro domains:
- IPR020453: Interleukin-22 (family) [1-172]
- IPR020423: Interleukin-10, conserved site (conserved_site) [77-97]
- IPR009079: Four-helical cytokine-like, core (homologous_superfamily) [22-172]
Sequence:
MSFSLMGTLAASCLLLVALWAQKADALPINSQCKLEAANFQQPYIVNRTFMLAKEASLADNNTDVRLIGEELFRGVKAKDQCYLMKQVLNFTLEDVLLPQSDRFQPYMQEVVPFLTKLSIHLSPCHISGDDQNIQKNVRQLKETVQKLGESGEIKAIGELDLLFMSLRNACV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (signaling receptor activator activity), GO:0048018 (receptor ligand activity), GO:0005125 (cytokine activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009719 (response to endogenous stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0048545 (response to steroid hormone), GO:0033993 (response to lipid), GO:0014070 (response to organic cyclic compound), GO:0031960 (response to corticosteroid), GO:0051384 (response to glucocorticoid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: PID domain-containing protein (B5BM46)
Organism: Caenorhabditis elegans
Function: Not known
InterPro domains:
- IPR006020: PTB/PI domain (domain) [192-323]
- IPR016698: Numb/numb-like (family) [107-682]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [164-322]
Sequence:
MNWIVHQQGSSNTMFYKCRPPIEFRFHKQTILGLKYDGLDRSSRSATSTIWVYDKCEFDNMIVPFMRHRPRNWDQESRYTAPRLMLCDTMSASQGNVFTRGLSRISRRKKKTKSIQNSLVSEQQPSFDAAIVPMPIPNDKSSIFSKGMDRLRRSLRLPKKRRDRSHDRHLSPDVTGGSKTEQWQPDEGAVRTGTCCFNVKYLGSVEVYESRGMQVCEGALKSLKASRRKPVKAVLYVSGDGLRVVDQGNSRGLLVDQTIEKVSFCAPDRQTDKGFAYICRDGASRRWMCHGFLATKETGERLSHAVGCAFSICLEKKKRRDEETAQVNVQSAQESTSSTPPKDIFHPNWEDNTSEGTSTQNPSNSRSNLAYQSFRKHVSIEDRYLDPQSVIINEVPASNHMDEIRRISKPRPTGNPALFLRQGSLRAPPDMPSSSDQFKRNMSLRTVSNNPTERSPEKKSFGTQLYNEPIYEGDEDPLGLGITPPVVTKTSGSLSNNGLDGINLNWKSIPAPVHQMQQHNANGDFVAAWPQNTIEKPTVGPLDKLQKQFEDIKLISISSGENTPTTRSKADEWLDDVLRVSMSMSPTSPSSDPPSTSSYSVLPKSGPPPAHAPPPLPVRQAVSNGSPSIYQQQLQQANSTRNSPAGINWNSSPNPMKISQPPAKPVDPFDVQWSRLAVNNTH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0051117 (ATPase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0033036 (macromolecule localization), GO:0010876 (lipid localization), GO:0051649 (establishment of localization in cell), GO:0046907 (intracellular transport), GO:0051668 (localization within membrane), GO:0006810 (transport), GO:0006869 (lipid transport), GO:0071702 (organic substance transport), GO:0016192 (vesicle-mediated transport), GO:0016197 (endosomal transport), GO:0098876 (vesicle-mediated transport to the plasma membrane), GO:0015914 (phospholipid transport), GO:0032456 (endocytic recycling), GO:0015748 (organophosphate ester transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0055037 (recycling endosome), GO:0005769 (early endosome), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)
Protein: Helix-loop-helix DNA-binding domain containing protein (Q2R0R9)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
InterPro domains:
- IPR011598: Myc-type, basic helix-loop-helix (bHLH) domain (domain) [161-216]
- IPR045843: Transcription factor IND-like (family) [49-237]
- IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [156-222]
Sequence:
MDARCANIWSSADARSEESEMIDQLKSMFWSSTDAEINFYSPDSSVNSCVTTSTMPSSLFLPLMDDEGFGTVQLMHQVITGNKRMFPMDEHFEQQQKKPKKKTRTSRSVSSSSTITDYETSSELVNPSCSSGSSVGEDSIAATDGSVVLKQSDNSRGHKQCSKDTQSLYAKRRRERINERLRILQQLVPNGTKVDISTMLEEAVQYVKFLQLQIKLLSSDDTWMFAPLAYNGMNMDLGHTLAENQE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: EF-hand protein NUCB1 (O44117)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
InterPro domains:
- IPR040250: Nucleobindin (family) [5-497]
- IPR011330: Glycoside hydrolase/deacetylase, beta/alpha-barrel (homologous_superfamily) [306-383]
- IPR011992: EF-hand domain pair (homologous_superfamily) [224-314]
- IPR057576: NUCB1-like, N-terminal domain (domain) [19-156]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [300-312]
Sequence:
MVQNVALLGLALIAISASIVALPVTQNKKDHKEAAESSTPATADVETALEYERYLREVVEALEADPEFRKKLDKAPEADIRSGKIAQELDYVNHHVRTKLDEIKRREVERLRELANQAYELSNDIDRKHLKVSQHLDHDNEHTFEIEDLRKLIQKTSDDLAEADRKRRGEFKEYEMQKEFEREAQKKEMDEESRKKFETELKEKEEKHKDHEKLHHPGNKAQLEDVWEKQDHMDKNDFDPKTFFSIHDVDSNGYWDEAEVKALFVKELDKVYQSDLPEDDMRERAEEMERMREHYFQETDMNHDGLISIDEFMVQTNKEEFQKDPEWETIDRQQQYTHEEYLEYERRRQEEVQRLIAQGQLPPHPNMPQGYYAAPPPGGVAYQQAPPGAQLHYQHPDQVHAQQQQQYAQQQQQYAQQYQQQQYGNGQQPVQLQPNQVYQHAGQIPQQQQPVYQNQPVYQQQQPVYQQQQPVQQQQKPVQQPVQQQPVQQQQQTAQQQPVAQQQIHNQSPPPVLNQQVPVQQQQKQHQESLNQQH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0005509 (calcium ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0000003 (reproduction), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0019953 (sexual reproduction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0042742 (defense response to bacterium), GO:0050829 (defense response to Gram-negative bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005576 (extracellular region), GO:0005615 (extracellular space), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)