lokahq/bioreason-rl huggingface dataset:
Protein: Gamma-aminobutyric acid receptor subunit rho-1 (GABA(A) receptor subunit rho-1) (GABAAR subunit rho-1) (GABA(C) receptor) (P24046)
Organism: Homo sapiens (Human)
Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission.
Subcellular location: Postsynaptic cell membrane {ECO:0000250|UniProtKB:P56475}; Multi-pass membrane protein {ECO:0000269|PubMed:37659407}. Cell membrane {ECO:0000269|PubMed:37659407}; Multi-pass membrane protein {ECO:0000269|PubMed:37659407}.
InterPro domains:
- IPR038050: Neuronal acetylcholine receptor (homologous_superfamily) [278-479]
- IPR006201: Neurotransmitter-gated ion-channel (family) [76-477]
- IPR036734: Neurotransmitter-gated ion-channel ligand-binding domain superfamily (homologous_superfamily) [72-280]
- IPR006028: Gamma-aminobutyric acid A receptor/Glycine receptor alpha (family) [284-478]
- IPR018000: Neurotransmitter-gated ion-channel, conserved site (conserved_site) [198-212]
- IPR008058: Gamma-aminobutyric-acid A receptor, Rho1 (family) [17-428]
- IPR008057: Gamma-aminobutyric-acid A receptor, Rho (family) [7-441]
- IPR036719: Neurotransmitter-gated ion-channel transmembrane domain superfamily (homologous_superfamily) [282-478]
- IPR006029: Neurotransmitter-gated ion-channel transmembrane domain (domain) [288-475]
- IPR006202: Neurotransmitter-gated ion-channel ligand-binding domain (domain) [81-280]
Sequence:
MLAVPNMRFGIFLLWWGWVLATESRMHWPGREVHEMSKKGRPQRQRREVHEDAHKQVSPILRRSPDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPDRMMVQLTLASERSSPQRKSQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYWSIFS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0016917 (GABA receptor activity), GO:0004890 (GABA-A receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0007267 (cell-cell signaling), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0099536 (synaptic signaling), GO:0099537 (trans-synaptic signaling), GO:0098916 (anterograde trans-synaptic signaling), GO:0007268 (chemical synaptic transmission)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Small ribosomal subunit protein bS21m (37S ribosomal protein mrp21, mitochondrial) (Q8WZK1)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Not known
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823372}.
InterPro domains:
- IPR001911: Small ribosomal subunit protein bS21 (family) [51-103]
- IPR038380: Small ribosomal subunit protein bS21 superfamily (homologous_superfamily) [62-98]
- IPR052837: Mitochondrial ribosomal protein bS21 (family) [29-121]
Sequence:
MNSSYFPGVLGVRWVHTNRKLQKRKEEHGAFQDSLHFMIPAAETKDLGASVTVGNSLTRAFRQVDRICQRNNVPRLFRSQRFYEKPSEKRSRVRSERHRARFRAGIVRLVNLAKNMRRWGY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0019538 (protein metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006412 (translation), GO:0009059 (macromolecule biosynthetic process), GO:0006518 (peptide metabolic process), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:0010467 (gene expression), GO:0043043 (peptide biosynthetic process), GO:0140053 (mitochondrial gene expression), GO:0032543 (mitochondrial translation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Pentatricopeptide repeat-containing protein At1g26460, mitochondrial (Q9FZD1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14671022}.
InterPro domains:
- IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [111-608]
- IPR002885: Pentatricopeptide repeat (repeat) [152-574]
- IPR044605: Pentatricopeptide repeat-containing protein At1g26460-like (family) [1-624]
Sequence:
MASHLFTRSRISLLKTLKPNPFTSASPIRAISGTPFLSQDPLLATESTDHDPSNHQSTSTPLPPNPATGSPLYQENWRSPIPNTPSFNQSLVPLGFLNQAPAPRIRALSETLDMNSLLNMFADWTASQRWSDMKQLFEVWVRSLDKNGKPNKPDVNLYNHYLRANLMMGASAGDMLDLVAPMEEFSVEPNTASYNLVLKAMYQARETEAAMKLLERMLLLGKDSLPDDESYDLVIGMHFGVGKNDEAMKVMDTALKSGYMLSTSVFTECVRSCVAKGRTDTLVSIIERCKAVDRNKSLCPSWILCNYIAEVAIQEDNSKLAFYAFEFMFKWITRGEMARPSVIFSVDEGLVVAGLASAARTCSSSLVEGSWTILKQSLRGRKAANPASYIAKINAYASLGNLQKAFTSLHELESAYADSEKEVVEEMLSPFTSLYPLVVACSKKGFETLDEVYFQLESLSQGDTPYKSVAALNCIILGCANTWDLDRAYQTFEAISASFGLTPNIDSYNALLYAFGKVKKTFEATNVFEHLVSIGVKPDSRTYSLLVDAHLINRDPKSALTVVDDMIKAGFEPSRETLKKLRRRCVREMDDENDDQVEALAKKFQIRMGSENRRNMLFNIDYSRGRALNN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0007276 (gamete generation), GO:0048229 (gametophyte development), GO:0048235 (pollen sperm cell differentiation), GO:0030154 (cell differentiation), GO:0009555 (pollen development), GO:0048232 (male gamete generation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: CD70 antigen (CD27 ligand) (CD27-L) (Tumor necrosis factor ligand superfamily member 7) (CD antigen CD70) (P32970)
Organism: Homo sapiens (Human)
Function: Cytokine which is the ligand for CD27. The CD70-CD27 pathway plays an important role in the generation and maintenance of T cell immunity, in particular during antiviral responses. Upon CD27 binding, induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11920585, ECO:0000269|PubMed:28011863, ECO:0000269|PubMed:28011864, ECO:0000269|PubMed:8120384, ECO:0000269|PubMed:8387892}; Single-pass type II membrane protein {ECO:0000255}.
InterPro domains:
- IPR042374: CD70 antigen (family) [1-193]
- IPR021184: Tumour necrosis factor, conserved site (conserved_site) [96-112]
- IPR006052: Tumour necrosis factor domain (domain) [56-191]
- IPR008983: Tumour necrosis factor-like domain superfamily (homologous_superfamily) [54-191]
Sequence:
MPEEGSGCSVRRRPYGCVLRAALVPLVAGLVICLVVCIQRFAQAQQQLPLESLGWDVAELQLNHTGPQQDPRLYWQGGPALGRSFLHGPELDKGQLRIHRDGIYMVHIQVTLAICSSTTASRHHPTTLAVGICSPASRSISLLRLSFHQGCTIASQRLTPLARGDTLCTNLTGTLLPSRNTDETFFGVQWVRP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0007267 (cell-cell signaling), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007166 (cell surface receptor signaling pathway), GO:0198738 (cell-cell signaling by wnt), GO:1905114 (cell surface receptor signaling pathway involved in cell-cell signaling), GO:0016055 (Wnt signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Endonuclease G inhibitor, isoform A (Endonuclease G inhibitor, isoform B) (Endonuclease G inhibitor, isoform C) (SD16985p) (Q9V3V9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
InterPro domains:
- IPR036494: Ku, C-terminal domain superfamily (homologous_superfamily) [7-359]
- IPR014893: Ku, C-terminal (domain) [31-142]
Sequence:
MSKRKAEDTQSDKMATAEKVAQNDYTIGLVDPVKDYQKLIETRVQVDEIVDDDVTKENFDRTAAAARDVIWRLLFDEAGTSQSNTEKASQLLEEYRGDACFYDPTPYNEWIVKLRDEVLKKELLDFWRDVLVKKQLGPCWSRDSDLFDSDDTPPLEFYAHAGCTAPFAASLKVRAALEEQASLDQDGPATPTTPGELSADDAAALSGEFEATLTKENPLEEYRTLMKRFVLTKIIVPDSVHQASVKKIAAAAREIIWKLLFDGTPSAEDQNKAAELLQEYKGDAGFYGPDDYNSWIFNLRDEVLTKELLDFWRDKMVKMELGPSCARDSDYYDNEDPLPFEFYEKAGCKAPFEGPVNDD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0004497 (monooxygenase activity), GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen), GO:0016712 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0071840 (cellular component organization or biogenesis), GO:0009892 (negative regulation of metabolic process), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0016043 (cellular component organization), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0006325 (chromatin organization), GO:0010629 (negative regulation of gene expression), GO:0010468 (regulation of gene expression), GO:0040029 (epigenetic regulation of gene expression), GO:0006338 (chromatin remodeling), GO:0045814 (negative regulation of gene expression, epigenetic), GO:0031507 (heterochromatin formation), GO:0070828 (heterochromatin organization), GO:0140719 (constitutive heterochromatin formation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Ribonuclease H2 subunit B (Ribonuclease HI subunit B) (A0A2R8Y687)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
InterPro domains:
- IPR041195: Rnh202, triple barrel domain (domain) [21-80]
- IPR019024: Ribonuclease H2 subunit B, wHTH domain (domain) [83-216]
- IPR040456: Ribonuclease H2 subunit B (family) [9-262]
Sequence:
MGLSSCYCPEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQLFEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDNVFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKTNNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSASLPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKVYQLVIL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0043687 (post-translational protein modification)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Anaphase-promoting complex subunit 16 (APC16) (Cyclosome subunit 16) (Q96DE5)
Organism: Homo sapiens (Human)
Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:20360068}. Nucleus {ECO:0000269|PubMed:20360068}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:20813266}.
InterPro domains:
- IPR029641: Anaphase-promoting complex subunit 16 (family) [1-110]
Sequence:
MAASSSSSSAGGVSGSSVTGSGFSVSDLAPPRKALFTYPKGAGEMLEDGSERFLCESVFSYQVASTLKQVKHDQQVARMEKLAGLVEELEADEWRFKPIEQLLGFTPSSG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0044248 (cellular catabolic process), GO:0009057 (macromolecule catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0006508 (proteolysis), GO:0044265 (cellular macromolecule catabolic process), GO:0030163 (protein catabolic process), GO:0043632 (modification-dependent macromolecule catabolic process), GO:0010498 (proteasomal protein catabolic process), GO:0051603 (proteolysis involved in protein catabolic process), GO:0019941 (modification-dependent protein catabolic process), GO:0043161 (proteasome-mediated ubiquitin-dependent protein catabolic process), GO:0006511 (ubiquitin-dependent protein catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: J domain-containing protein (Q9TY07)
Organism: Caenorhabditis elegans
Function: Not known
InterPro domains:
- IPR001623: DnaJ domain (domain) [6-75]
- IPR043183: DnaJ homolog subfamily B member 2/6-like (family) [9-237]
- IPR036869: Chaperone J-domain superfamily (homologous_superfamily) [4-120]
Sequence:
MAPREDSPYITLGISSTSDDVEIKKAYRKLALKWHPDKHTDDKSKEEAEQKFKKIAQAYEILTDKKKRADLDRTENPGLHRRRSTPGGMHRMHSHDMFRSPFDIFREFFGNRDPFENVFFDDAFTFPDVDSYAFKHPPRSADFTTKNHYHRFPSSRVHIFYDENKNTKERDDKNTFSTVIRFSSPTEPGKNATVRKTSTSTKLVDGKKIVTKTVENGDEHIVEVHEDGELKCRTVTTPPTSPTVTVAAI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0031072 (heat shock protein binding), GO:0030544 (Hsp70 protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0006950 (response to stress), GO:0009628 (response to abiotic stimulus), GO:0009408 (response to heat), GO:0009266 (response to temperature stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Cilia- and flagella-associated protein 91 (Flagellar-associated protein 91) (Q386N1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Axoneme-associated protein involved in flagellum motility and central pair positioning.
Subcellular location: Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:32161152}.
InterPro domains:
- IPR026720: Cilia- and flagella-associated protein 91 (family) [19-708]
- IPR032840: CFAP91 domain (domain) [135-289]
Sequence:
MYYRTQQKPASVLGANGFTAEVGGRDRVRYFRPPVEVAGVPMRYSGIDTVRFSATAPTTPNLPRTFAETRFDRPTSMAAGLVGPPHHLPSLPRRAGAAPPHPVKAKSVKLPPQRTKRVEKLASTIGTDGKCDAAMQTVFRENEAQTLPYTPNYYIPEGGDPNPQVLGLMELHWNEGLPAGKEEVELIQRLRRRRAVEASLLDETSKEAKMENFCKLYDLEVKEREEREQHFENLRKRRLDQIHEALQERERARDELNRQRLEKVKEQRLANLQRVIEQMESKRVGMGRKALAEQASKAPAAAGRGLYAVDPIETFKRKPDLIQTYARRGTGAVEPQLCTNNGGGSASASPRRDRSRKPLRNYRQYDIQPAMLKYEGGIAELEANKIPKIQQIAPNAFAAPENHAINSLPSLYQRREATRVVEALEYVHAKIHKSDTPAETIRVLELYRATPRPQRPDTPTLELEGDVNEAVEESCTLLQRLLRGRAVQNDFFDGKERCRGLIEELQAASNAKYAERSAEEKQAEAEEKMREAIADSIGNEAQGDIICDTLDYLFHEMTRQQDLLALEALRHEAEAVRAEREAREAELRAQERILHDKEAVQYAAYVRAIEDIVECYSHDLYATVAEECAMEEAIEAECQRLEQLPPPTSNILSDPEVAENLVCDVLDNFVLPAVIDMVRMKPEELDRKAPAAAAAGFRQRSPNEKETKE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0007017 (microtubule-based process), GO:0016043 (cellular component organization), GO:0000226 (microtubule cytoskeleton organization), GO:0044085 (cellular component biogenesis), GO:0030030 (cell projection organization), GO:0006996 (organelle organization), GO:0001578 (microtubule bundle formation), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0007010 (cytoskeleton organization), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0044782 (cilium organization), GO:0035082 (axoneme assembly), GO:0060271 (cilium assembly), GO:0120031 (plasma membrane bounded cell projection assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0005930 (axoneme), GO:0005737 (cytoplasm), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0099568 (cytoplasmic region), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0005929 (cilium), GO:0032838 (plasma membrane bounded cell projection cytoplasm), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0097014 (ciliary plasm)
Protein: Epididymal-specific lipocalin-9 (MUP-like lipocalin) (Q8WX39)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Secreted.
InterPro domains:
- IPR012674: Calycin (homologous_superfamily) [22-168]
- IPR000566: Lipocalin/cytosolic fatty-acid binding domain (domain) [34-155]
- IPR022272: Lipocalin family conserved site (conserved_site) [27-40]
- IPR002345: Lipocalin (family) [4-140]
- IPR002971: Major urinary protein (family) [34-126]
Sequence:
MALLLLSLGLSLIAAQEFDPHTVMQRNYNVARVSGVWYSIFMASDDLNRIKENGDLRVFVRNIEHLKNGSLIFDFEYMVQGECVAVVVVCEKTEKNGEYSINYEGQNTVAVSETDYRLFITFHLQNFRNGTETHTLALYETCEKYGLGSQNIIDLTNKDPCYSKHYRSPPRPPMRW
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0007610 (behavior), GO:0007635 (chemosensory behavior)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Putative metacaspase (E9AEY0)
Organism: Leishmania major
Function: Not known
InterPro domains:
- IPR050452: Metacaspase (family) [59-317]
- IPR011600: Peptidase C14, caspase domain (domain) [63-308]
Sequence:
MADLFDIWGIGAVASLIPMLANGLLLVDRPKRVDINAGRRLIHTVRPIIPYRAPVPYTGGRVRALFIGINYTGMRNALRGCVNDVSSMLGTLQQISFPISECCILVDDPSFPGFCGMPTRDNIIKHMLWLTGDVRPGDVLFFHFSGHGGQAKATRDSEEKYDQCLIPLDHVKNGSILDDDLFLMLVAPLPSGVRMTCVFDCCHSASMLDLPFSYVAPRVGGGGACEYMQQVRRGNFSNGDVVMFSGCTDRGTSADVQNGGHANGAATLAFTWSLLNTHGLSYLNILLKTREELRKKGRVQVPQLTSSKPIDLYKPFSLFGMITVNASMMHCVPQQYQQRPQSLPPQVMPPATGYPVHVPPPPQGYYPPPQSPGWGLGYPVQGIPVQQATLGVSRCPPSQYLPAPPPAVYAPPPPGQRGPPQPPPAQYTFSPLPPG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008234 (cysteine-type peptidase activity), GO:0004175 (endopeptidase activity), GO:0004197 (cysteine-type endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0006508 (proteolysis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle)