lokahq/bioreason-rl huggingface dataset:
Protein: Coatomer subunit epsilon (Epsilon-coat protein) (Epsilon-COP) (Q28104)
Organism: Bos taurus (Bovine)
Function: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. {ECO:0000250}.
InterPro domains:
- IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [17-307]
- IPR006822: Coatomer, epsilon subunit (family) [14-308]
Sequence:
MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKPSSPERDVERDVFLYRAYLAQRKYGVVLDEIKPSSAPELQAVRMFAEYLASDSRRDAIVAELDREMSRSVDVTNTTFLLMAASIYFYDQNPDAALRTLHQGDSLECMAMTVQILLKLDRLDLARKELKKMQDQDEDATLTQLATAWVSLAAGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGVLQEALDKDSGHPETLINLVVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYRAKENDFDRLVLQYAPSA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0033036 (macromolecule localization), GO:0051641 (cellular localization), GO:0070727 (cellular macromolecule localization), GO:0008104 (protein localization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0005798 (Golgi-associated vesicle), GO:0030135 (coated vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0030137 (COPI-coated vesicle), GO:0097708 (intracellular vesicle)
Protein: Neutral sphingomyelinase activation associated factor (A0A8I6API9)
Organism: Rattus norvegicus (Rat)
Function: Not known
InterPro domains:
- IPR057496: FAN-like, N-terminal PH domain (domain) [9-160]
- IPR001680: WD40 repeat (repeat) [614-912]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [568-911]
- IPR000409: BEACH domain (domain) [282-567]
- IPR004182: GRAM domain (domain) [168-284]
- IPR036372: BEACH domain superfamily (homologous_superfamily) [275-567]
- IPR023362: PH-BEACH domain (domain) [181-278]
- IPR050865: BEACH Domain-Containing (family) [164-910]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [609-910]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [185-275]
Sequence:
MSTRLPSSSMLRFSLLLLNLEEYYFEQHTAFHVQHQGSPEERKIRGSLKICSKSVIFEPDAISQPILKIPLRDCLKIGKHGENGANKHFAKAKSLGISLIFSQVYFIKEHNIVAPYKIERGKMEYVFQLEVSGKVEDVVETLLQLHRASCLDKLGDQMAMITAILQSRLARTSFDKNRFQSVSEKLHMECKAEMVTPLVTNPGHVCITDTNLYFQPLNGYPKPVVQITLQDVRRIYKRRHGLMPLGLEVFCTEDDLCSDIYLKFYEPQDRDDLYFYIATYLEHHVAEHTAESYMLQWQRGHLSNYQYLLHLNNLADRSCNDLSQYPVFPWVISDYSSPELDLSNPATFRDLSKPVGALNPERLERLLTRYQEMPEPKFMYGSHYSSPGYVLFYLVRIAPEYMLCLQNGRFDNADRMFNSIAETWKNCLDGATDFKELIPEFYDEDASFLINSLKLDLGKRQGGQMVDDVELPAWASSPQDFLQKNKDALESSYVSEHLHEWIDLIFGYKQKGSEAIGAHNVFHPLTYEGGVDLNSIEDPDDKVAMLTQILEFGQTPKQLFVTPHPRRITPKFKSLSQASSYNASMTDSPVSPGEESFEDLTEESKTLAWNNITKLQLHEQYKIHKEAVTGIAVSCNGSSVFTTSQDSTLKMFSKESKMLQRSISFSNMALSSCLLLPGDTTVISSSWDNNVYFYSIAFGRRQDTLMGHDDAVSKICWHNDRLYSASWDSTVKVWSGVPAEMPGTKRHQFDLLAELEHDVSVNTINLNAVSTLLVSGTKEGLVNIWDLTTATLLHQISCHSGTVCDAAFSPDSRHVLSTGVDGCLNVIDVQTGMLISSMASEEPQRCFVWDGNSVLSGSRTGELLVWDLLGAKVSERIQGHTGAVTCIWMNEQCSSIITGGEDRQVMFWKLQY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0008047 (enzyme activator activity), GO:0060229 (lipase activator activity), GO:0016004 (phospholipase activator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0010941 (regulation of cell death), GO:0010942 (positive regulation of cell death), GO:0043067 (regulation of programmed cell death), GO:0043068 (positive regulation of programmed cell death), GO:0043065 (positive regulation of apoptotic process), GO:0042981 (regulation of apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction), GO:0045202 (synapse)
Protein: Photosynthetic NDH subunit of lumenal location 1, chloroplastic (PsbP-like protein 2) (O80634)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (Probable). Required for accumulation of the chloroplast NAD(P)H dehydrogenase (NDH) complex.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000269|PubMed:18431481}; Peripheral membrane protein {ECO:0000305}; Lumenal side {ECO:0000305}.
InterPro domains:
- IPR016123: Mog1/PsbP, alpha/beta/alpha sandwich (homologous_superfamily) [89-235]
- IPR002683: PsbP, C-terminal (domain) [87-235]
Sequence:
MAVSSLSIRCGGFSPTISHKTEILCPNPSLKACCLLSSGGKADSSESTYQKGSGNNWKRRQALVGVGTLVATSIPATLLLAEEIPKSYSPFVDREDGYSYYYPSDWREFDFRAHDSAFKDRYLQLQNVRVRFIPTEKNDIHEVGPMEEVVYDLVKHKFAAPNQVATIYDMKERVEDGKNYYTFEYGLRTPIYATTSFATVAVGNNRYYTLIVGANERRWRKVKKQLQVVADSLKILQI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0015979 (photosynthesis), GO:0006091 (generation of precursor metabolites and energy), GO:0019684 (photosynthesis, light reaction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005829 (cytosol), GO:0098796 (membrane protein complex), GO:0031975 (envelope), GO:0005737 (cytoplasm), GO:0031977 (thylakoid lumen), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0034357 (photosynthetic membrane), GO:0043229 (intracellular organelle), GO:0019867 (outer membrane), GO:0009536 (plastid), GO:0043228 (non-membrane-bounded organelle), GO:0043227 (membrane-bounded organelle), GO:0009507 (chloroplast), GO:0042651 (thylakoid membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031976 (plastid thylakoid), GO:0098588 (bounding membrane of organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0009526 (plastid envelope), GO:0042170 (plastid membrane), GO:0031968 (organelle outer membrane), GO:0009579 (thylakoid), GO:0055035 (plastid thylakoid membrane), GO:0009535 (chloroplast thylakoid membrane), GO:0009534 (chloroplast thylakoid)
Protein: WbnF (O51400)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Function: Not known
InterPro domains:
- IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [1-347]
- IPR001509: NAD-dependent epimerase/dehydratase (domain) [3-257]
Sequence:
MKIFLTGIAGFIGFHVAKKLVEKGHEVLGIDVLNDYYELKFKHERLEALGFCSKDVKTHKIIKSEKYNNLSFAYLDILNKDKLLELFKDHKFTHVCHLAAQAGIRDSLENPDSYVSINIVGFFNVLDVCRVYKENIEHFVYASTSSVYGINENMPSSEDSITDHPLNLYAASKKSNEMMAHAYSASFNIPTTGLRFFTVYGTYGRPDMALYLFSDGIKNGKAINIFNNGNMARDFTYVGDIADGVYKVLKNPAKSDCNFDVKNPNSSTSSFPYRIYNIGTGHATKLLDFISELEANFDKKALKNYMPMQKADVVESCCDILKLKNDVGYEAKVSIKEGIKEFSQWYKMLESTKKT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016835 (carbon-oxygen lyase activity), GO:0016836 (hydro-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0006793 (phosphorus metabolic process), GO:0009225 (nucleotide-sugar metabolic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0019438 (aromatic compound biosynthetic process), GO:0018130 (heterocycle biosynthetic process), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:0009226 (nucleotide-sugar biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Merozoite surface protein 7 (Q8IDX8)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Not known
InterPro domains:
- IPR024781: Merozoite surface protein, C-terminal (domain) [217-346]
Sequence:
MKSNIIFYFSFFFVYLYYVSCNQSTHSTPVNNEEDQEELYIKNKKLEKLKNIVSGDFVGNYKNNEELLNKKIEELQNSKEKNVHVLINGNSIIDEIEKNEENDDNEENNDDDNTYELDMNDDTFLGQNNDSHFENVDDDAVENEQEDENKEKSESFPLFQNLGLFGKNVLSKVKAQSETDTQSKNEQEISTQGQEVQKPAQGGESTFQKDLDKKLYNLGDVFNHVVDISNKKNKINLDEYGKKYTDFKKEYEDFVLNSKEYDIIKNLIIMFGQEDNKSKNGKTDIVSEAKHMTEIFIKLFKDKEYHEQFKNYIYGVYSYAKQNSHLSEKKIKPEEEYKKFLEYSFNLLNTM
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0044403 (biological process involved in symbiotic interaction), GO:0051701 (biological process involved in interaction with host), GO:0044000 (movement in host), GO:0044409 (entry into host)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0043226 (organelle), GO:0005576 (extracellular region), GO:0043657 (host cell), GO:0043227 (membrane-bounded organelle), GO:0033643 (host cell part), GO:0043230 (extracellular organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0020003 (symbiont-containing vacuole), GO:0030430 (host cell cytoplasm), GO:0033655 (host cell cytoplasm part)
Protein: 32 kDa beta-galactoside-binding lectin lec-3 (32 kDa GBP) (Q09581)
Organism: Caenorhabditis elegans
Function: Binds galactose.
InterPro domains:
- IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [7-292]
- IPR001079: Galectin, carbohydrate recognition domain (domain) [9-290]
- IPR044156: Galectin-like (family) [84-289]
Sequence:
MAEPKSFNIPYRSKLTERIEPGQTLIIRGKTIDESKRFNINLHKDSPDFSGNDVPLHLSIRFDEGKIVYNAYTKGTWGKEERAKNPIKKGDDFDIRIRAHDSKFQVSINHKEVKNFEHRIPLNSVSHLSIDGDVVLNHVQWGGKYYPVPYESGIAADGLVPGKTLVVYGTPEKKAKKFNINLLKKNGDIALHFNPRFDEKANGFMCAKPTPGSVVRNSLVNGEWGNEEREGKNPFERLTAFDLEIRNEEFAFQIFVNGERFASYAHRVDPHDIAGLQIQGDIELTGIQVVNNQPAQE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0040017 (positive regulation of locomotion), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0051239 (regulation of multicellular organismal process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0040012 (regulation of locomotion), GO:0048522 (positive regulation of cellular process), GO:0010171 (body morphogenesis), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:2000145 (regulation of cell motility), GO:0035556 (intracellular signal transduction), GO:0050920 (regulation of chemotaxis), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009790 (embryo development), GO:0048608 (reproductive structure development), GO:0045137 (development of primary sexual characteristics), GO:0007548 (sex differentiation), GO:2000147 (positive regulation of cell motility), GO:0016477 (cell migration), GO:0061458 (reproductive system development), GO:0010172 (embryonic body morphogenesis), GO:0008406 (gonad development), GO:0030335 (positive regulation of cell migration), GO:0030334 (regulation of cell migration), GO:0001667 (ameboidal-type cell migration), GO:1903354 (regulation of distal tip cell migration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: STAS domain-containing protein (Q5B9Q0)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
InterPro domains:
- IPR036513: STAS domain superfamily (homologous_superfamily) [559-703]
- IPR018045: Sulphate anion transporter, conserved site (conserved_site) [119-140]
- IPR011547: SLC26A/SulP transporter domain (domain) [90-479]
- IPR002645: STAS domain (domain) [566-692]
- IPR001902: SLC26A/SulP transporter (family) [66-703]
Sequence:
MPGDIPTKVGHGLAKVLRLKLPEKPQPDAVTRGESTFSVGTFDTYSYVEPEPTAAEWFAEITPSWKEIGLYFYRLFPFLSWITRYNTTWLIGDLVAGITVGAVVVPQGMAYAQLAQLPVEYGLYSSFMGVLIYWFFATSKDITIGPVAVMSTLVGNIVTEAAETLPDVEPHVIASCLAVICGGIVTFMGLARLGFIVDFIPLPAITAFMTGSAINICSGQVSTMLGETDKVNTRGATYNTIIQTLRALPSSTLDAAMGVTACAMLYIIRFACNTAAKKQPHRAKMWFFISTLRTVFVILFYTMISAATNLHRRDNPAFKVLGTVPRGFKHAAVPTVNAEIIKTFASELPAAVIVLLIEHIAISKSFGRVNNYTIDPSQELVAIGVTNLLGPFLGGYPATGSFSRTAIKSKAGVRTPLAGVITAVVVLLAIYALPALFWYIPKASLAGVIIHAVGDLITPPNVVYQFYRVSPLDCVIFFVGVIVTVFTSIEIGVYCTVCISVAVLLFRVAKARGEFLGRVTIHSVVGDHVLEESKPGLGDADRTRSIFLPLNHADGSNPEIEIEQPYPGIFIYRFSEGFNYPNANHYTDYLVETIFQKTRRTNPFTYSNPGDRPWNNPGPRKGKQEEDRSHLPTLRAVILDFSSVNNVDVTSVQNLIDVRNQLDIYASPHTVQWHFAHVKNRWTKRALAAAGFGYPTPQSEDGFHRWKPIFSVTEIEGQSSAAAHAEIVANENTRQASSHGHDLESGIKNPSHTAERETHGIEESSNSSIGEDDKLQRDLKDSKAYQNRRKMAVVQGVNLPFFHIDITSALESALANSQEEPADVSSD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901682 (sulfur compound transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015116 (sulfate transmembrane transporter activity), GO:0015103 (inorganic anion transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0098660 (inorganic ion transmembrane transport), GO:0006810 (transport), GO:0072348 (sulfur compound transport), GO:0071705 (nitrogen compound transport), GO:0098661 (inorganic anion transmembrane transport), GO:0015698 (inorganic anion transport), GO:0008272 (sulfate transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Chaperone protein DNAJ, putative (Q38DE1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
InterPro domains:
- IPR001305: Heat shock protein DnaJ, cysteine-rich domain (domain) [164-249]
- IPR036410: Heat shock protein DnaJ, cysteine-rich domain superfamily (homologous_superfamily) [174-245]
- IPR008971: HSP40/DnaJ peptide-binding (homologous_superfamily) [149-381]
- IPR036869: Chaperone J-domain superfamily (homologous_superfamily) [35-141]
- IPR044713: DnaJ homolog subfamily A member 1/2-like (family) [38-395]
- IPR001623: DnaJ domain (domain) [38-111]
- IPR012724: Chaperone DnaJ (family) [36-414]
- IPR002939: Chaperone DnaJ, C-terminal (domain) [150-371]
- IPR018253: DnaJ domain, conserved site (conserved_site) [77-96]
Sequence:
MLRFTSVSSIWRRLAAAPPTAATAAFANVSKRQSSSNKDYYKILGVSQSASQSDIKKAYRKRALETHPDQGGNKEDFAEVAEAYECLSNEEKRRIYDQYGSEAAANMNAGGGMGGFGGRSAEDIFAEFFKGGMGGFGGNRSAGPPQVPPLEVTLRMTLEEVYKGASKSPRVNRPVVCSDCRGFGTKSQKKKPKCSECDGSGHVVQHHRFGPGMVQQTVSQCPRCGGAGTVAKPDDKCPKCKGMGYRHLVQSVSIDIPAGVPPDVTLVVRGEGGTMPEAEPGDLHVHVEVEEHNVFKRRGNDLVVERDVTLSEALLEFDLSLKTLDGRSITVKSPKSSVLQPNSVLRVAGEGMPNSSGGNGDLYIVTKLKLPRTLTDQQKEAVKKAFGEPKKKDPDSGSDKTVTASVLRGGVREMEEALHSNWDSERGGGSQQGNGRRRSGRKQHTAECVHQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0009628 (response to abiotic stimulus), GO:0019222 (regulation of metabolic process), GO:0006950 (response to stress), GO:0009408 (response to heat), GO:0009266 (response to temperature stimulus), GO:0060255 (regulation of macromolecule metabolic process), GO:0010468 (regulation of gene expression), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Polyamine oxidase (A0A8I6A890)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
InterPro domains:
- IPR050281: Flavin monoamine oxidase and related enzymes (family) [53-264]
- IPR036188: FAD/NAD(P)-binding domain superfamily (homologous_superfamily) [4-261]
- IPR002937: Amine oxidase (domain) [63-260]
Sequence:
MAARGPRVLVVGGGIAGLGAVQRLCHHRAAPHLRVLEATACAGGRIRSERCFGFLKEHQDTFFEPPLPAKKAEAIRKLGFGTNNKIFLEFEEPFWEPDCQFIQVVWEDTSPLQDSPLSLQDTWFKKLIGFLVLPSFESSHVLCAFIAGLQSEFMETLSDEEVLLSLTQVLRRVTGNPQLPAAKSVLRSRWHSAPYTRGSYSYVAVGSTGDDLDLMAQPLPADGTGTQLQVLFAGEATHRTFYSTTHGALLSGWREADRLIGLWDSQAEQSRPRL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016645 (oxidoreductase activity, acting on the CH-NH group of donors), GO:0016647 (oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901575 (organic substance catabolic process), GO:0009308 (amine metabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0006576 (biogenic amine metabolic process), GO:0009310 (amine catabolic process), GO:0042402 (cellular biogenic amine catabolic process), GO:0006595 (polyamine metabolic process), GO:0008216 (spermidine metabolic process), GO:0006598 (polyamine catabolic process), GO:0008215 (spermine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0042579 (microbody), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005777 (peroxisome)