lokahq/bioreason-rl huggingface dataset:
Protein: Cytochrome P450 81F4 (EC 1.14.-.-) (Q9SZU1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in indole glucosinolate biosynthesis. Catalyzes hydroxylation reactions of the glucosinolate indole ring. Converts indol-3-yl-methylglucosinolate (I3M) to 1-hydroxy-indol-3-yl-methylglucosinolate (1OH-I3M) intermediate. This hydroxy intermediates is converted to 1-methoxy-indol-3-yl-methylglucosinolate (1MO-I3M) by indole glucosinolate methyltransferase 1 and 2 (IGMT1 and IGMT2).
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
InterPro domains:
- IPR036396: Cytochrome P450 superfamily (homologous_superfamily) [17-489]
- IPR017972: Cytochrome P450, conserved site (conserved_site) [428-437]
- IPR001128: Cytochrome P450 (family) [32-473]
- IPR002401: Cytochrome P450, E-class, group I (family) [59-458]
- IPR050651: Plant Cytochrome P450 Monooxygenase (family) [12-489]
Sequence:
MFNYVIILPLALFLLAYKFFFTSKKQRYYLPPSPSYSLPILGHHLLIKPPVHRLFHRLSNIHGPIFYLRLGSRRAVVISSSSLARECFTGQNDVIVSNRPRFLTSKYIAYNYTTIATTSYGDHWRNLRRICSLEIVSSKRLANFLHIRKEEIQRMLTRLSRDARVGKEVELESILYDLTFNNIVRMVTGKIYYGDDVSDKEEAELFKKLFTFITTNSGARHPGEYLPFMKIFGGSFEKEVKAAAKVIDEMLQRLLDECKSDKDGNTMVNHLLSLQQDDPEYYTDIIIKGLMLGIMVASSETSALTIEWAMASLLNHPKVLDKVKLEIDEIIGQDRLIEESDIANLPYLQNVVSETLRLHPAAPVLVPRSTAEDIKIGGYDVPRDTMVMVNAWAIHRDPDLWTEPERFNPERFNGGEGEKDDVRMLIAFGSGRRICPGVGLAHKIVTLALGSLIQCFDWKKVNEKEIDMSEGPGMAMRMMVPLRALCKTRPIMNKLPAYTKV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0004497 (monooxygenase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0019748 (secondary metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006790 (sulfur compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0006082 (organic acid metabolic process), GO:0019757 (glycosinolate metabolic process), GO:0042430 (indole-containing compound metabolic process), GO:0019760 (glucosinolate metabolic process), GO:0016143 (S-glycoside metabolic process), GO:1901657 (glycosyl compound metabolic process), GO:0043436 (oxoacid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Protein hook homolog (DdHk3) (Q54IK9)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Cytoskeletal linker protein involved in tethering membrane bound organelles to the cytoskeleton.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250}.
InterPro domains:
- IPR001715: Calponin homology domain (domain) [1-113]
- IPR008636: Hook, C-terminal (domain) [283-732]
- IPR036872: CH domain superfamily (homologous_superfamily) [1-145]
- IPR043936: HOOK, N-terminal (domain) [4-138]
Sequence:
MIETSFIKWINSFKDLSNSIEDLKELSNGTIFNEICCQIAPKYFDIDSLRKDGLDNWIFREENIKNIVERVDEFYIEEMGLNDQISSINCEEIANENIDEIILLIEAILGMAMESENNEAVIENILSLDQDTQNDLMVVVAKIQQSHQPNTVDNSKSFDKDGSILSQSPSQSNNSISNNNNNNNIDSSNISKSNISSNNNNNNSSNNNKEEILNLQNEIEKLKREKQEIQNDLDESNIQLSNVTMDRDRITIDKQKTEEVCSSLHESIIGLQKQLDETMAQTTTMNALNDETYKTEINDLHMQVESKEKQLSELKKKVDEANRLANENRSLRDEIDILREKAANAEATEEKLKKHQKKIEEIGDLKKKIKELEDQNDSYIQQTLDLEEQLSKNNTYRTQADSGKQQISSLKIELAKLELSLKSIKEDRDKLSESLNTVELERDSLQSQVTNLRNTIDNQQQEYETKFVDLQSSISLNSGGSGGLGDEVIDGSTKERIARLERDNKRLKEVAEKASELENQLEDANQSKELLTIQIKQLEEQKQQSNNTNNNNNNNNMVDSSEIESLKQQLKEKEKEISTLKRKLEESNLSLDENRKQLVELSQRPTTQSPGDIEKLENYENLLKENDGLEGRLRAARNIIKDLREKHKSYSNQETQLATKDEVITKLEGLVKKKTDINEDLRKQLEEGREESQREINLMLSAFLKIGLEMEQVKIQNISSSKEPRSFLNKKRAD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0015631 (tubulin binding), GO:0008017 (microtubule binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0007017 (microtubule-based process), GO:0022402 (cell cycle process), GO:0007049 (cell cycle), GO:0016043 (cellular component organization), GO:0000226 (microtubule cytoskeleton organization), GO:0007059 (chromosome segregation), GO:0006810 (transport), GO:0031023 (microtubule organizing center organization), GO:0007098 (centrosome cycle), GO:0016192 (vesicle-mediated transport), GO:0006996 (organelle organization), GO:0007010 (cytoskeleton organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005813 (centrosome), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015630 (microtubule cytoskeleton)
Protein: Choline-phosphate cytidylyltransferase 1 (AtCCT1) (EC 2.7.7.15) (CTP:phosphocholine cytidylyltransferase 1) (Phosphorylcholine transferase 1) (Q9ZV56)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays an important role in the biosynthesis of the phospholipid phosphatidylcholine. Catalyzes the formation of CDP-choline.
InterPro domains:
- IPR014729: Rossmann-like alpha/beta/alpha sandwich fold (homologous_superfamily) [13-252]
- IPR004821: Cytidyltransferase-like domain (domain) [36-168]
- IPR041723: CTP:phosphocholine cytidylyltransferase domain (domain) [33-185]
- IPR045049: Choline-phosphate cytidylyltransferase Pcy1-like (family) [24-315]
Sequence:
MSNVIGDRTEDGLSTAAAASGSTAVQSSPPTDRPVRVYADGIYDLFHFGHARSLEQAKLAFPNNTYLLVGCCNDETTHKYKGRTVMTAEERYESLRHCKWVDEVIPDAPWVVNQEFLDKHQIDYVAHDSLPYADSSGAGKDVYEFVKKVGRFKETQRTEGISTSDIIMRIVKDYNQYVMRNLDRGYSREDLGVSFVKEKRLRVNMRLKKLQERVKEQQERVGEKIQTVKMLRNEWVENADRWVAGFLEIFEEGCHKMGTAIVDSIQERLMRQKSAERLENGQDDDTDDQFYEEYFDHDMGSDDDEDEKFYDEEEVKEEETEKTVMTDAKDNK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016779 (nucleotidyltransferase activity), GO:0070567 (cytidylyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006629 (lipid metabolic process), GO:0019637 (organophosphate metabolic process), GO:0006793 (phosphorus metabolic process), GO:0046470 (phosphatidylcholine metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0046486 (glycerolipid metabolic process), GO:0008610 (lipid biosynthetic process), GO:0006644 (phospholipid metabolic process), GO:0045017 (glycerolipid biosynthetic process), GO:0090407 (organophosphate biosynthetic process), GO:0006650 (glycerophospholipid metabolic process), GO:0046474 (glycerophospholipid biosynthetic process), GO:0008654 (phospholipid biosynthetic process), GO:0006656 (phosphatidylcholine biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Vitamin B12 transporter BtuB (Cobalamin receptor) (Outer membrane cobalamin translocator) (P06129)
Organism: Escherichia coli (strain K12)
Function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB. Is also a receptor for bacteriophages BF23 and C1, and for A and E colicins.
Subcellular location: Cell outer membrane {ECO:0000255|HAMAP-Rule:MF_01531, ECO:0000269|PubMed:12595710, ECO:0000269|PubMed:12652322, ECO:0000269|PubMed:2687240, ECO:0000269|PubMed:2982793}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01531, ECO:0000269|PubMed:12595710, ECO:0000269|PubMed:12652322, ECO:0000269|PubMed:2687240, ECO:0000269|PubMed:2982793}.
InterPro domains:
- IPR036942: TonB-dependent receptor-like, beta-barrel domain superfamily (homologous_superfamily) [151-614]
- IPR010917: TonB-dependent receptor, conserved site (conserved_site) [597-614]
- IPR010101: TonB-dependent vitamin B12 transporter BtuB (family) [2-614]
- IPR039426: TonB-dependent receptor-like (family) [4-614]
- IPR037066: TonB-dependent receptor, plug domain superfamily (homologous_superfamily) [27-150]
- IPR000531: TonB-dependent receptor-like, beta-barrel (domain) [170-588]
- IPR010916: TonB box, conserved site (conserved_site) [1-33]
- IPR012910: TonB-dependent receptor, plug domain (domain) [41-146]
Sequence:
MIKKASLLTACSVTAFSAWAQDTSPDTLVVTANRFEQPRSTVLAPTTVVTRQDIDRWQSTSVNDVLRRLPGVDITQNGGSGQLSSIFIRGTNASHVLVLIDGVRLNLAGVSGSADLSQFPIALVQRVEYIRGPRSAVYGSDAIGGVVNIITTRDEPGTEISAGWGSNSYQNYDVSTQQQLGDKTRVTLLGDYAHTHGYDVVAYGNTGTQAQTDNDGFLSKTLYGALEHNFTDAWSGFVRGYGYDNRTNYDAYYSPGSPLLDTRKLYSQSWDAGLRYNGELIKSQLITSYSHSKDYNYDPHYGRYDSSATLDEMKQYTVQWANNVIVGHGSIGAGVDWQKQTTTPGTGYVEDGYDQRNTGIYLTGLQQVGDFTFEGAARSDDNSQFGRHGTWQTSAGWEFIEGYRFIASYGTSYKAPNLGQLYGFYGNPNLDPEKSKQWEGAFEGLTAGVNWRISGYRNDVSDLIDYDDHTLKYYNEGKARIKGVEATANFDTGPLTHTVSYDYVDARNAITDTPLLRRAKQQVKYQLDWQLYDFDWGITYQYLGTRYDKDYSSYPYQTVKMGGVSLWDLAVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015343 (siderophore-iron transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0006811 (monoatomic ion transport), GO:0015850 (organic hydroxy compound transport), GO:0006812 (monoatomic cation transport), GO:0015711 (organic anion transport), GO:0030001 (metal ion transport), GO:0000041 (transition metal ion transport), GO:0006826 (iron ion transport), GO:1901678 (iron coordination entity transport), GO:0015891 (siderophore transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0031975 (envelope), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030312 (external encapsulating structure), GO:0009279 (cell outer membrane), GO:0019867 (outer membrane), GO:0030313 (cell envelope)
Protein: Chordin-like protein 1 (Neuralin-1) (Neurogenesin-1) (Ventroptin) (Q920C1)
Organism: Mus musculus (Mouse)
Function: Seems to antagonize the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation (By similarity). Antagonizes the function of BMP7 and may thus play an important role in the embryonic bone formation. Shows no inhibitory effect on the inducing activity of BMP2. Plays a role during anterior segment eye development (By similarity).
Subcellular location: Secreted {ECO:0000305}.
InterPro domains:
- IPR045717: Chordin-like protein 1/2 (family) [3-447]
- IPR045716: Chordin-like protein 1/2, C-terminal (domain) [328-447]
- IPR001007: VWFC domain (domain) [30-318]
Sequence:
MDGMKYIISLFFIFVFLEGSKTEQVKHSDTYCVFQDKKYRVGEKWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPSLHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFIAEGLFQNRQPNQCSQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRGDAELSWEHADGDIFRQPANREARHSYLRSPYDPPPNRQAGGLPRFPGSRSHRGAVIDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPEEPPSQNFDSKGSFCGEETMPVYESVFMEDGETTRKVALETERPPQVEVHVWTIQKGILQHFHIEKISKRMFGELHHFKLVTRTTLNQWKLFTEGEAQLSQMCSSQVCRTELEDLVQVLYLGRPEKDHC
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0045165 (cell fate commitment), GO:0001709 (cell fate determination), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0022008 (neurogenesis), GO:0007399 (nervous system development), GO:0030182 (neuron differentiation), GO:0048699 (generation of neurons)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Teleost multiple tissue opsin b (A0A2R8Q4C0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU004951}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU004951}.
InterPro domains:
- IPR017452: GPCR, rhodopsin-like, 7TM (domain) [106-354]
- IPR000276: G protein-coupled receptor, rhodopsin-like (family) [91-362]
- IPR002962: Peropsin (family) [110-340]
- IPR001760: Opsin (family) [112-345]
- IPR050125: G-protein coupled receptor opsins (family) [79-373]
- IPR027430: Visual pigments (opsins) retinal binding site (binding_site) [338-354]
Sequence:
MWQQCSCALGELQNHRNDGLENSPKLKWITKHSRYKTKLIKSFTQAIINGAMIESNVSRSCEWCAGGGEGTGAHLDENHSDHSLSPTGHLVVAVCLGFIGTFGFLNNTLVLVLFCRYKVLRSPMNCLLISISVSDLLVCVLGTPFSFAASTQGRWLIGRAGCVWYGFINSFLGVVSLISLAVLSYERYCTMMGSTQADSTNYRKVVIGIAFSWIYSMVWTLPPLFGWSCYGPEGPGTTCSVNWAARTPNNVSYIVCLFVFCLILPFIVIVYSYGRLLQAITQVSRINTVVSRKREQRVLFMVVTMVVCYLLCWLPYGIMALLATFGHPGLVTPAASIVPSLLAKSSTVINPIIYIFMNKQFCRCFHALIMCTTPERGSSFKNSSKVTKTLRTVRRANGQNVTFAVASAVHRTPYSDRQKSSSEGEKLPPATGQGTSKPVVSLVAYYNG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0009881 (photoreceptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007186 (G protein-coupled receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0043227 (membrane-bounded organelle), GO:0120025 (plasma membrane bounded cell projection), GO:0005929 (cilium), GO:0097730 (non-motile cilium)
Protein: Serine repeat antigen 1 (EC 3.4.22.-) (O96167)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Not known
InterPro domains:
- IPR013128: Peptidase C1A (family) [459-753]
- IPR000668: Peptidase C1A, papain C-terminal (domain) [525-771]
- IPR038765: Papain-like cysteine peptidase superfamily (homologous_superfamily) [495-776]
- IPR025661: Cysteine peptidase, asparagine active site (active_site) [733-752]
Sequence:
MKFFIPYVYIICVIFIINVIRTRGEEDDDNNNISGKSILGTSHNNISNIDLSSIPNLDSNIHASFSSDTKEWSPNNLTSKKKKKKKEIRPKDIMSNSDSSNTSSINKQNNNQIKSVLLKENKGVKITGPCNVNLSIFLVPHIYIDVETKYNNIELKYELDEFSDSIKFKDTTTELRTSDDTLMNTNFNVGVSRDTLDKDRLYNICAENKTFKFVVYIKDNILTLKWKVYETGVTNNKVDIRQYKMKELTRPITTIQIHSVSENKDTHLLESKNYVIKTDIPETCDVMATNCFLSGNINIEKCLECTLLVQNNDTSSECFTYVSNDVRENFNQIKAEAEDDENFRNYHLTDTINNILKRIYKINKNEGKKELITLEELDNFLKESITDYCKILREIDTNGTLVNHELGNNVDVFNNLIRLLKLHKNESISTLHNKLRNSAICMKYPDKWIEKKTGLILPNVVNNNIIYNNKYEKLNEEKKRKIYDNKDDSKISDIINIKKYIFTNNTLKYFNNDKQFCNSSFCNRLKDENNCISKIQIEDQGNCAISWIFASKYYLETLKCMKGYEPHAISALYIANCSKRKHKNRCNVGSNPLEFLQIIEENQFLPMDTNYLYSYTKVGNDCPDEEKNWVNLLKHTRMLNYNNKHRSTLSTKAYRAYESEHFKDKMDTFIKLIKDEIMNNGSVIAYVKAENVLGYELNGKNVQNLCGDKTPDHAVNIVGYGNYINDEDEKKSYWIVRNSWGKYWGDEGYFKVDMYGPSTCEDNFIHTVVVFNINMPKSKKSPVKITFPLYNYYLKYSPDFYHNLYYKNFNSKKSMKLVNASDEHKNIYSQEDKVNHKKGSKILNSEVTTSLLSQEISQRRGEDDDIDTLIGDSPDINEQEKNIKDEFNKSSITHNSVSSSNITKSNKNTNKVKIYHIIKHVKNTKIKIGFVKYDNYNTIGTNHTCSRSYSEDQEKHEGCIKFCELHWNECKDKTSPGYCLTKLKGSNECFFCYV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048583 (regulation of response to stimulus), GO:0002682 (regulation of immune system process), GO:0050776 (regulation of immune response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0043226 (organelle), GO:0005576 (extracellular region), GO:0043657 (host cell), GO:0043227 (membrane-bounded organelle), GO:0033643 (host cell part), GO:0043230 (extracellular organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0020003 (symbiont-containing vacuole), GO:0030430 (host cell cytoplasm), GO:0033655 (host cell cytoplasm part)
Protein: C3H1-type domain-containing protein (Q388W9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
InterPro domains:
- IPR000571: Zinc finger, CCCH-type (domain) [44-168]
Sequence:
MSSQDNRAKYVQNGVMEVFDPNFKYLYLVPAHFVLHVPPARLNISRLVICRNYRSGVPNSCAKEESCRFVHADVDYSTLEAHPIHVNYIWRHEDHCTYERLPAGDVLEVCSQENPQEHELISSELVLVTRGSVAHHNALPHSLMRCPLYTTNRMCSRGERCSFIHTLCVDPTVVGDFKRAPARTAAVTPTPRSPAVASATDSQKMPRTFASGTPMLSDFCISSPEREAPALSMGAGGYTALSFRVDAAGEPLPATCSVIPRCRVTARVRTSTVVKSRPTLVAAFSDASVSRRSAMATNSRPASYCHNPYYPVLCRS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010468 (regulation of gene expression), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0035770 (ribonucleoprotein granule), GO:0036464 (cytoplasmic ribonucleoprotein granule), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0010494 (cytoplasmic stress granule), GO:0043232 (intracellular non-membrane-bounded organelle)
Protein: Negative elongation factor complex member E (E9PD43)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
InterPro domains:
- IPR033102: Negative elongation factor E (family) [1-217]
Sequence:
MLVIPPGLSEEEEALQKKFNKLKKKKKALLALKKQSSSSTTSQGGVKRSLSEQPVMDTATATEQAKQLVKSGAISAIKAETKNSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADDDLQESSRRPQRKSLYESDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRKGNTLY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0010468 (regulation of gene expression), GO:0043484 (regulation of RNA splicing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0005622 (intracellular anatomical structure), GO:0016020 (membrane), GO:0071944 (cell periphery), GO:0031974 (membrane-enclosed lumen), GO:0016604 (nuclear body), GO:0005654 (nucleoplasm), GO:0005886 (plasma membrane), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)