lokahq/bioreason-rl huggingface dataset:
Protein: Ubiquinol-cytochrome c reductase complex assembly factor 6 (Protein BRAWNIN) (Q69YU5)
Organism: Homo sapiens (Human)
Function: Required for the assembly and stability of the mitochondrial ubiquinol-cytochrome c reductase complex (complex III (CIII) or cytochrome b-c1 complex), a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain (ETC) which drives oxidative phosphorylation. Mediates early complex III biogenesis (By similarity). Participates in regulating the levels of electron transport chain proteins, and therefore energy supply, in response to changes in energy demand (By similarity). Also required for cytochrome c oxidase complex (complex IV) assembly.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:32161263, ECO:0000269|PubMed:34969438}; Single-pass type II membrane protein {ECO:0000305|PubMed:32161263}.
InterPro domains:
- IPR027858: Protein BRAWNIN (family) [1-60]
Sequence:
MPAGVPMSTYLKMFAASLLAMCAGAEVVHRYYRPDLTIPEIPPKRGELKTELLGLKERKHKPQVSQQEELK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0006996 (organelle organization), GO:0043933 (protein-containing complex organization), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly), GO:0007005 (mitochondrion organization), GO:0033108 (mitochondrial respiratory chain complex assembly), GO:0017004 (cytochrome complex assembly), GO:0017062 (respiratory chain complex III assembly), GO:0034551 (mitochondrial respiratory chain complex III assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Small ribosomal subunit protein mS45 (37S ribosomal protein S35, mitochondrial) (O60096)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for mitochondrial protein synthesis. Has a role in mitochondrial integrity and cell respiration.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:18245278}.
InterPro domains:
- IPR021036: Small ribosomal subunit protein mS45 (family) [25-313]
Sequence:
MRNSVEFSQLGLKTAFNLSQNKTYTSAVKKQFFSTGAFLSNGGNIDLNKHTQKNIDSKYVACNSRSVTPPNDVASSVSKNTLRHKQRLMMAQWLMSPEVQKAKSSSSGNVGLGPNTNQPFPLNPFFKPPRPISHSLRMKITDEYLQGASIEVLARKFNTSPQRIEALIKLRRINDEFEEKKKPILHSYNEVMEKMLNACTKPEMMQFNDGNDIPLRSNPVSLWKSLPEGETFTPQEAAKILKWPSIEELNMRQNATHFHKTSDEHKDLNEDEELISSSPSEVGKRVFRLIDLSTGNVYRRDTGGDIYVKRKKSTT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0019538 (protein metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006412 (translation), GO:0009059 (macromolecule biosynthetic process), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:0006518 (peptide metabolic process), GO:0010467 (gene expression), GO:0140053 (mitochondrial gene expression), GO:0043043 (peptide biosynthetic process), GO:0032543 (mitochondrial translation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Claudin domain-containing protein 2 (Q8NHS1)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
InterPro domains:
- IPR004032: PMP-22/EMP/MP20 (family) [21-45]
- IPR004031: PMP-22/EMP/MP20/Claudin (family) [10-145]
- IPR050579: Peripheral myelin protein 22/Epithelial membrane protein-like (family) [8-151]
Sequence:
MGVKRSLQSGGILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECNHGICSSIPCQTTLAVTVACMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKNAWKNNVFFSWSYFSGWLALPFSILAGFCFLLADMIMQSTDAISGFPVCL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0001562 (response to protozoan), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0042832 (defense response to protozoan)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Lipopolysaccharide export system protein LptC (Q9KP51)
Organism: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Function: Not known
Subcellular location: Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_01915}; Single-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_01915}.
InterPro domains:
- IPR026265: Lipopolysaccharide export system protein LptC (family) [3-185]
- IPR052363: Lipopolysaccharide export system LptC (family) [1-184]
- IPR010664: Lipopolysaccharide assembly, LptC-related (family) [9-183]
Sequence:
MSLSRIVYVLLLFIASWSLYYLLGQEQDSKIQVAPNLELPMFSGENLENISYDEQGIRNYVITSIHLDHYAKSGNTLFKAPILKVYREGTLQEWEITARRGILSKDQVLTLYDDVLAKNLLPDSGFDTLTTSEMSIQLKSRDFWADKPVELRGPQFETHGQAMKGNFADHSAELYNQVQGRYETLTP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0033036 (macromolecule localization), GO:0010876 (lipid localization), GO:0006810 (transport), GO:0006869 (lipid transport), GO:0071702 (organic substance transport), GO:1901264 (carbohydrate derivative transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0031975 (envelope), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:1990351 (transporter complex), GO:0005886 (plasma membrane), GO:0030313 (cell envelope)
Protein: Kappa-casein (B2Z898)
Organism: Bos taurus (Bovine)
Function: Not known
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
InterPro domains:
- IPR000117: Kappa casein (family) [1-53]
Sequence:
TEIPTINTIASGEPTSTPTIEAVESTVATLEASPEVIESPPEINTVQVTSTAV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0044085 (cellular component biogenesis), GO:0016043 (cellular component organization), GO:1901700 (response to oxygen-containing compound), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0097305 (response to alcohol), GO:1901654 (response to ketone), GO:0032355 (response to estradiol), GO:0033993 (response to lipid), GO:0048545 (response to steroid hormone), GO:0043933 (protein-containing complex organization), GO:0014070 (response to organic cyclic compound), GO:0022607 (cellular component assembly), GO:0032570 (response to progesterone), GO:0065003 (protein-containing complex assembly), GO:0031960 (response to corticosteroid), GO:0051259 (protein complex oligomerization), GO:0051385 (response to mineralocorticoid), GO:0051260 (protein homooligomerization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: S protein (Q91QT1)
Organism: Avian infectious bronchitis virus (strain Beaudette US) (IBV)
Function: Not known
Subcellular location: Host endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000256|ARBA:ARBA00034689}. Virion membrane {ECO:0000256|ARBA:ARBA00004182}.
InterPro domains:
- IPR043473: Spike glycoprotein S2 superfamily, coronavirus (homologous_superfamily) [781-1081]
- IPR043614: Spike glycoprotein S2, coronavirus, C-terminal (domain) [1113-1161]
- IPR044873: Spike glycoprotein S2, coronavirus, heptad repeat 1 (domain) [769-874]
- IPR043607: Coronavirus spike glycoprotein S1, C-terminal (domain) [429-494]
- IPR044874: Spike glycoprotein S2, coronavirus, heptad repeat 2 (domain) [1024-1105]
- IPR002552: Spike glycoprotein S2, coronavirus (domain) [583-1110]
Sequence:
MLVTPLLLVTLLCALCSAVLYDSSSYVYYYQSAFRPPNGWHLQGGAYAVVNISSEFNNAGSSSGCTVGIIHGGRVVNASSIAMTAPSSGMAWSSSQFCTAHCNFSDTTVFVTHCYKHGGCPITGMLQQNLIRVSAMKNGQLFYNLTVSVAKYPTFRSFQCVNNLTSVYLNGDLVYTSNETIDVTSAGVYFKAGGPITYKVMREVKALAYFVNGTAQDVILCDGSPRGLLACQYNTGNFSDGFYPFTNSSLVKQKFIVYRENSVNTTCTLHNFIFHNETGANPNPSGVQNIQTYQTKTAQSGYYNFNFSFLSSFVYKESNFMYGSYHPSCKFRLETINNGLWFNSLTVSIAYGPLQGGCKQSVFKGRATCCYAYSYGGPSLCKGVYSGELDHNFECGLLVYVTKSGGSRIQTATEPPVITQNNYNNITLNTCVDYNIYGRTGQGFITNVTDSAVSYNYLADAGLAILDTSGSIDIFVVQGEYGLNYYKVNPCEDVNQQFVVSGGKLVGILTSRNETGSQLLENQFYIKITNGTRRFRRSITENVANCPYVSYGKFCIKPDGSIATIVPKQLEQFVAPLFNVTENVLIPNSFNLTVTDEYIQTRMDKVQINCLQYVCGSSLDCRKLFQQYRPVCDNILSVVNSVGQKEDMELLNFYSSTKPAGFNTPVLSNVSTGEFNISLLLTTPSSRRKRSLIEDLLFTSVESVGLPTNDAYKNCTAGPLGFFKDLACAREYNGLLVLPPIITAEMQAMYTSSLVASMAFGGITAAGAIPFATQLQARINHLGITQSLLLKNQEKIAASFNKAIGHMQEGFRSTSLALQQIQDVVSKQSAILTETMASLNKNFGAISSVIQEIYQQFDAIQANAQVDRLITGRLSSLSVLASAKQAEYIRVSQQRELATQKINECVKSQSIRYSFCGNGRHVLTIPQNAPNGIVFIHFSYTPDSFVNVTAIVGFCVKPANASQYAIVPANGRGIFIQVNGSYYITARDMYMPRAITAGDVVTLTSCQANYVSVNKTVITTFVDNDDFDFNDELSKWWNDTKHELPDFDKFNYTVPILDIDSEIDRIQGVIQGLNDSLIDLEKLSILKTYIKWPWYVWLAIAFATIIFILILGWVFFMTGCCGCCCGCFGIMPLMSKCGKKSSYYTTFDNDVVTEQYRPKKSV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0016032 (viral process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0061024 (membrane organization), GO:0061025 (membrane fusion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: ATPase subunit 9, putative (EC 3.6.3.14) (Q385P0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
InterPro domains:
- IPR035921: F/V-ATP synthase subunit C superfamily (homologous_superfamily) [46-117]
- IPR020537: ATP synthase, F0 complex, subunit C, DCCD-binding site (binding_site) [81-102]
- IPR002379: V-ATPase proteolipid subunit C-like domain (domain) [54-115]
- IPR000454: ATP synthase, F0 complex, subunit C (family) [17-118]
- IPR038662: F1F0 ATP synthase subunit C superfamily (homologous_superfamily) [46-118]
Sequence:
MMRRLALQSSLRRVTPAAVSVMTPAKVTSPIGHAIAIRQASTVAISVQGLHYVGTGLAAIALAGVGLGIGTIFGNLLVACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:1990542 (mitochondrial transmembrane transport), GO:0034220 (monoatomic ion transmembrane transport), GO:0098660 (inorganic ion transmembrane transport), GO:0006810 (transport), GO:0098655 (monoatomic cation transmembrane transport), GO:0098662 (inorganic cation transmembrane transport), GO:0006811 (monoatomic ion transport), GO:0006812 (monoatomic cation transport), GO:1902600 (proton transmembrane transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0098798 (mitochondrial protein-containing complex), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:0031975 (envelope), GO:1902494 (catalytic complex), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0016469 (proton-transporting two-sector ATPase complex), GO:0043229 (intracellular organelle), GO:0045263 (proton-transporting ATP synthase complex, coupling factor F(o)), GO:0098800 (inner mitochondrial membrane protein complex), GO:0033177 (proton-transporting two-sector ATPase complex, proton-transporting domain), GO:0005739 (mitochondrion), GO:1904949 (ATPase complex), GO:0043227 (membrane-bounded organelle), GO:0005740 (mitochondrial envelope), GO:0043231 (intracellular membrane-bounded organelle), GO:0005753 (mitochondrial proton-transporting ATP synthase complex), GO:0000276 (mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)), GO:0019866 (organelle inner membrane), GO:0045259 (proton-transporting ATP synthase complex), GO:0031966 (mitochondrial membrane), GO:0005743 (mitochondrial inner membrane)
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q38B11)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
InterPro domains:
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [31-327]
- IPR001849: Pleckstrin homology domain (domain) [371-489]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [163-175]
- IPR051131: NEK Ser/Thr protein kinase family, NIMA subfamily (family) [31-308]
- IPR017441: Protein kinase, ATP binding site (binding_site) [39-62]
- IPR000719: Protein kinase domain (domain) [33-303]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [368-490]
Sequence:
MSSTDAMIGRVCRTFGEAFAKDEATAKEQKKKYWIKRVLGSGATGTVLCAKRTSDGETFAVKVVDLEGMNEGDKNRAQAEVHCLMNCDFFSILKCHEDFAKKDPQNEVNVLMIALVLDYANAGDLRQEIKSRAKTSRAFREHEAGLLFIQVLLALHHVHSRHMIHRDIKSANILLCSNGLIKLGDFGFTKMYSATVSDDVGKTFCGTPYYVAPEIWRRKPYSKKADLFSLGVLLYELLTLRRPFDGESMRDVMNRTLSGQYDPLPPETSPEMAEIVSLLLSSDPKQRPCSGKLLDMPICKLFMSGLLEIVQTQPAFEGPLRDVIPSDIRNIKQLLRADKRSVVKQMDESYSTAISTAVLEGATPCSGLGDVTLYEGIIKKQSSDMSWKRRYLCIRAELENGEDLSVGKLPKFKSLHLVLAISKDTLQRQCIATPFTDLEDVFPVPSKYTGSNAPNVFAVAFKAGRRLLFQARSPAKRDAWMQKIQEVLGL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0007267 (cell-cell signaling), GO:0009607 (response to biotic stimulus), GO:0044145 (modulation of formation of structure involved in a symbiotic process), GO:0007154 (cell communication), GO:0051606 (detection of stimulus), GO:0009595 (detection of biotic stimulus), GO:0009372 (quorum sensing), GO:0060245 (detection of cell density)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0005737 (cytoplasm), GO:0120025 (plasma membrane bounded cell projection), GO:0099568 (cytoplasmic region), GO:0043227 (membrane-bounded organelle), GO:0005929 (cilium), GO:0032838 (plasma membrane bounded cell projection cytoplasm), GO:0097014 (ciliary plasm)
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q8IXA3)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
InterPro domains:
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [40-328]
- IPR022247: Casein kinase 1 gamma C-terminal (domain) [331-392]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [160-172]
- IPR050235: Casein Kinase 1 Ser/Thr Protein Kinase (family) [43-373]
- IPR017441: Protein kinase, ATP binding site (binding_site) [50-73]
- IPR000719: Protein kinase domain (domain) [44-329]
Sequence:
MDHPSREKDERQRTTKPMAQRSAHCSRPSGSSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTHRDRPSQQQPLRNQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEAKCIMFHKPWHWSQSSAVKMKFVVFLNMNVNFKCI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0006793 (phosphorus metabolic process), GO:0036211 (protein modification process), GO:0006796 (phosphate-containing compound metabolic process), GO:0043412 (macromolecule modification), GO:0006468 (protein phosphorylation), GO:0018193 (peptidyl-amino acid modification), GO:0016310 (phosphorylation), GO:0018105 (peptidyl-serine phosphorylation), GO:0018209 (peptidyl-serine modification)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Clu domain-containing protein (Q75JJ2)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Not known
InterPro domains:
- IPR027523: CLU domain containing protein (family) [44-856]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [1043-1274]
- IPR033646: CLU central domain (domain) [607-699]
- IPR025697: CLU domain (domain) [278-520]
Sequence:
MGYDYNEVFSYLGEKENALSQRLLRLKVSPDILRQKYDNVQPITQQQQPNNRYDNASPNIVQSSSSSSSSRYDNFNKDDIKSESVSSSSSLTTQSNNRYDNASPTISDSFSSNKARYDNTSNSTQDFSSSESNFYSYKGSDQSESIYGICNVQDSQSSDPYSIYGSKTTNSGGNEDNHDIDLKKPYFMHDISENDLLVLESLVRYNKVLELPKNENNNNISDISTTLSSSSSSSPSGQRLQVLQSGYLDDNIKSNPYSSYSHPKFLTNDNLNVSNASSSFSSGSSGSSITGKKMDNIALYYWSSEFQRLLEMDDCLEKFERLSSLEHDFVYAAESYGRIIISENFLANELKTIKPVSVGGIAGGEKYIVQGILFKFALENEAFGLYGNDENAMKTAAHELNGCASFLNCGVKGLHVPLMAFIDYRGFRLMAMSLLPISKKSLIYGSCDAGQTVHTSNNIFNNLFLNASKVINLKQHFVEDISGDIKSISGPIDIEGHLGGDNRFYLLDFARLSPPEPPKHRGSYLYKLLRLELVRKYQKPLCSDAFSPMSTIDSNKHNVEVQEAYDDLMNNIIPKFSKDIQTRDEIGLKTNFLQDLLSNISDKITDVSKLLHAEGINIRYIGEVASHCTSIGYKRFFTIEAIVRTLKSLARELLRREMRNIHLPSDYPYRSLLLKFLNLLFDEYKDKTEYIWNKIILEKMEKKFQNIFNNVNTEKEEPELNENSPKLPVTPQEIIKNLLTTLPTREMILKKFCKSIGLVISKIAISQFNNSDSFVFVDTDIKEIKTLSTRLNVIDYADGMSLYYKSMASGLSDTSKHRLLTISRERLEQSILTMNNNFQIVIQLAKVLTLLAKTSQDYTKKQLYYVLANKKLSTFDTIGVVQSQVLLLKICRVKTILSHLKFEGFILPKEIEEIEIVLNEIIEQSPDKAYPSYLLAKFFDHLYKYNSKFDYSKVLTAYNNIFKIDPNYQKAHIGISLFLLVTQGSNKNFSKEKVSEHITKAFSISKNIESIIDKIKPLIDFSPWIFFETSRTVPKLRSIVKNSLEEKYSIKKEKFTIPLNIQFEVEDLDYFENINVEKIYFDEHINSNSIEVFSKIKPDIQSFISRKLKINDCSKLKSLSNLSNITYLNFGNNQNGINEWVLSDLITPKLRKLKLYEIPTLTDLIVKLIASTCKDLEVLDLGGCSGILGEDFNELYKGCPSVVKLALPPFVDNLIVSESISKLRLIKLDLMKCSKLTFQSYSKLLDSSKTLLKIRSPSGIPFFFIEPQNLTSRHEKVNSFEPALRYSIGGMELFNIKIGGAPQGGKTFELFFNNKHPLVKFRDPPNPSFNFFKAMHAVNIKSHSTQLNIHKNFGTSWTSVESSHPISINTSICNFKVEYQGNSYQFLLDTSGFNGSTFSNEVSISNNKIAFISNKKTNGSHVEIEIKFKTTILPIWIAITSGGLK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050794 (regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0033043 (regulation of organelle organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: LANA (E5LC01)
Organism: Human herpesvirus 8 (HHV-8) (Kaposi's sarcoma-associated herpesvirus)
Function: Not known
InterPro domains:
- IPR037007: Epstein Barr virus nuclear antigen-1, DNA-binding domain superfamily (homologous_superfamily) [965-1104]
- IPR048523: Protein LANA1-like, DNA-binding domain (domain) [983-1100]
Sequence:
MAPPGMRLRSGRSTGAPLTRGSCRKRNRSPERCDLGNDLHLQPRRKHVADSVDGRECGPHTLPIPGSPTVFTSGLPAFVSSPTLPVAPIPSPAPATPLPPPALLSPVTTSSSPIPPSHPVSPGTTDTHSPSPALPPTQSPESSQRPPLSSPTGRPDSSTPMRPPPSQQTTPPHSPTTPPPEPPSKSSPDSLAPSTLRSLRKRRLSSPQGPSTLNPICQSPPVSPPRCDFANRSVYPPWATESPIYVGSSSDGDTPPRQPPTSPISIGSSSPSEGSWGDDTAMLVLLAEIAEEASKNEKECSENNQAGEDNGDNEISKESQVDKDDNDNKDDEEEQETDEDDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEEDEEEDEEEEEDEEDDDDEDNEDEEDDEEEDKKEDEEDGGDGNKTLSIQSSQQQQEPQQQEPQQQEPQQQEPLQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQREPQQQEPQQREPQQQEPQQREPQQREPQQREPQQREPQQREPQQREPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQEQQDEQQQQDEQQQQDEQQQQDEQQQEEQEQQEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQEQELEEVEEQEQEQEEQELEEVEEQEQEQEEQEEQELEEVEEQEEQELEEVEEQEEQELEEVEEQEQQGVEQQEQETVEEPIILHGSSSEDEMEVDYPVVSTHEQIASSPPGDNTPDDDPQPGPSREYRYVLRTSPPHRPGVRMRRVPVTHPKKPHPRYQQPPVPYRQIDDCPAKARPQHIFYRRFLGKDGRRDPKCQWKFAVIFWGNDPYGLKKLSQAFQFGGVKAGPVSCLPHLGPDQSPITYCVYVYCQNKDTSKKVQMARLAWEASHPLAGNLQSSIVKFKKPLPLTQPGENQGPGDSPQEMT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0016032 (viral process), GO:0019058 (viral life cycle)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0043657 (host cell), GO:0033643 (host cell part), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0033647 (host intracellular organelle), GO:0033648 (host intracellular membrane-bounded organelle)