lokahq/bioreason-rl huggingface dataset:
Protein: BTB domain-containing protein (Voltage-gated K+ channel isoform 1) (G5EEK7)
Organism: Caenorhabditis elegans
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
InterPro domains:
- IPR003974: Potassium channel, voltage dependent, Kv3 (family) [48-439]
- IPR028325: Voltage-gated potassium channel (family) [6-451]
- IPR027359: Voltage-dependent channel domain superfamily (homologous_superfamily) [141-310]
- IPR003131: Potassium channel tetramerisation-type BTB domain (domain) [7-97]
- IPR000210: BTB/POZ domain (domain) [5-105]
- IPR011333: SKP1/BTB/POZ domain superfamily (homologous_superfamily) [1-115]
- IPR003968: Potassium channel, voltage dependent, Kv (family) [47-411]
- IPR005821: Ion transport domain (domain) [170-423]
Sequence:
MDSEYRIILNVGGVRHETYKHTLKKIPATRLSRLTTNLANYDPVLNEYFFDRHPGVFAQILNYYRTGKLHYPLDVCGPLFEEELKYWGLDSNECEPCCWMTLSGTRDTQDVLKTLDELDIEVDQTEGPELYKRFGWEDDYHNDSLSAWQKIKPRIWRLFDEPNSSRSAQFIAAISVFFLITAIIVFCLKTHPGLRIPELAPFGNFSRNHRSTSSRIHPAQINIDKANSRPHPTFMYIETICNIWFTIEILARFSSCPSRFEYLRAPVNIIDIVATLTFYIDLLSSMFGATADLEFFSIIRIMRLFKLTHHNSGLKILMHTFRASAKELMLLVFFLVLGVVVFASLVYYAERVESNEDNQFVSIPIGLWWAIVTMTTIGYGDITPHTYLGRLIGSICALAGVLTIALPVPVIVSNFAMFYSHTQARSKMPKKRRGVLSMDQVAQHVKHAPVRNSNGPTQRKNMENTPLVSNNHTPPHTLI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0015267 (channel activity), GO:0022839 (monoatomic ion gated channel activity), GO:0022836 (gated channel activity), GO:0005244 (voltage-gated monoatomic ion channel activity), GO:0022832 (voltage-gated channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0006810 (transport), GO:0034220 (monoatomic ion transmembrane transport), GO:0006811 (monoatomic ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Glutathione hydrolase proenzyme 1 (EC 3.4.19.13) (Gamma-glutamyltransferase 1) (Gamma-glutamyltranspeptidase 1) (EC 2.3.2.2) [Cleaved into: Glutathione hydrolase 1 heavy chain; Glutathione hydrolase 1 light chain] (Q9US04)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Catalyzes the transfer of the gamma-glutamyl moiety of glutathione (GSH) and other gamma-glutamyl compounds to amino acids and peptides. Major GSH-degrading enzyme, catalyzing the hydrolytic release of L-glutamate from GSH.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
InterPro domains:
- IPR043137: Gamma-glutamyltranspeptidase, small subunit, C-terminal domain (homologous_superfamily) [435-630]
- IPR029055: Nucleophile aminohydrolases, N-terminal (homologous_superfamily) [92-630]
- IPR043138: Gamma-glutamyltranspeptidase, large subunit (homologous_superfamily) [323-434]
- IPR000101: Gamma-glutamyltranspeptidase (family) [75-630]
Sequence:
MGINTSSAQSSGAASIARSSVNVKSGNRHLSSNKKSATSALEERASRPSILVTFLVLAGTILSLYIWPILSPDLFFANQRCSFKYKNKGSQRVVVEGKNGVVATEEETCSQIGVGILKAGGNAVDAAIASGICIGAVNSFSSGIGGGGFMLIRHPNGTAHSLNFRETAPAGASKNMFHGNSTLSQVGGLSVAVPGEIAGYERAWKMYGSLPWHKLFEPTIRLMRDGMPMPKELASRIRRPEFSYFKTHPDWSKIFAPEGVFLHVGEKFYRPALASTLEEIAKFGPEVFYTGKIAERLVKFVQQQGGILTMEDMANFSVVVEEPIYGNFYDREVITCGSPCSGEALILGLNVLSKVDLSEGTSILGCEMTDIGVHHLIETMKWMSAGRTVLADPTFYNNTDHVEQLLSLEYADEIRNNISNERTFDFTHYKAEYDFPNDHGTTHLSVIDKDNMAVGLTASINLMFGSQLLEPETGIILNDHMDDFASPGIVNAFGLSPSPYNFIAPGKRPQSSAVPTILVYNGEVEMVLGGSGGSRIVTAVLDTIIKKYKWGKSLLESVESPRFHHQLMPNIVYIDETVEIEVLRALEKFGHIVDLIPVQYPFSEIQAVFRTNGTLYGLSDSRKQAVAAAY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008242 (omega peptidase activity), GO:0070003 (threonine-type peptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0009056 (catabolic process), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0071704 (organic substance metabolic process), GO:1901575 (organic substance catabolic process), GO:0006749 (glutathione metabolic process), GO:0009410 (response to xenobiotic stimulus), GO:0070887 (cellular response to chemical stimulus), GO:0006805 (xenobiotic metabolic process), GO:0071466 (cellular response to xenobiotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Adenosylhomocysteinase (EC 3.13.2.1) (A5PMG3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
InterPro domains:
- IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [259-419]
- IPR000043: Adenosylhomocysteinase-like (family) [61-500]
- IPR042172: Adenosylhomocysteinase-like superfamily (homologous_superfamily) [61-500]
- IPR015878: S-adenosyl-L-homocysteine hydrolase, NAD binding domain (domain) [259-420]
- IPR020082: S-adenosyl-L-homocysteine hydrolase, conserved site (conserved_site) [146-298]
Sequence:
MNHGYDFPRIQFANQEDKQEFSKFPTKTGRRSLSRSISQSSTDSYSSAASYTDSSDDETSPREKSQVNSKGSSDFCVKNIKQAEFGRREIEIAEQDMSALISLRKRAQGEKPLAGAKVAGCTHITAQTAVLIETLVALGAQCRWTACNIYSTQNEVAAALAESGVSVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPSVFKKVRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVCGYGEVGKGCCSALKALGAIVCVTEIDPICALQACMDGFRVVKLNEVVRQMDMVITCTGNKNVVTREHLDRMKNGCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHVIWPDGKRVILLAEGRLLNLSCSTVPSFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPNFDAHLTELSDEQAKYMGLNKNGPFKPNYYRY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0016787 (hydrolase activity), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0005515 (protein binding), GO:1901265 (nucleoside phosphate binding), GO:0000166 (nucleotide binding), GO:0043621 (protein self-association), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0017076 (purine nucleotide binding), GO:0046914 (transition metal ion binding), GO:0030554 (adenyl nucleotide binding), GO:0005507 (copper ion binding), GO:0051287 (NAD binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0007389 (pattern specification process), GO:0003002 (regionalization), GO:0009953 (dorsal/ventral pattern formation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: PMS1 homolog 2, mismatch repair system component (A0A8I5ZND0)
Organism: Rattus norvegicus (Rat)
Function: Not known
InterPro domains:
- IPR036890: Histidine kinase/HSP90-like ATPase superfamily (homologous_superfamily) [11-231]
- IPR042121: MutL, C-terminal domain, regulatory subdomain (homologous_superfamily) [317-416]
- IPR014790: MutL, C-terminal, dimerisation (domain) [277-421]
- IPR037198: MutL, C-terminal domain superfamily (homologous_superfamily) [275-453]
- IPR014762: DNA mismatch repair, conserved site (conserved_site) [105-111]
- IPR042120: MutL, C-terminal domain, dimerisation subdomain (homologous_superfamily) [280-453]
- IPR038973: DNA mismatch repair protein MutL/Mlh/Pms-like (family) [14-251]
- IPR002099: DNA mismatch repair protein MutL/Mlh/PMS (family) [15-242]
Sequence:
MEPTEGASTECAKAIKPIDGKSVHQICSGQVVLSLSTAVKELIENSVDAGATSIDLRLKDYGVDLIEVSDNGCGVEEENFEGLALKHHTSKIREFADLTQVETFGFRGEALSSLCALSDVTISTCHVSASIGTRLVLDHNGKIIQKTPCPRPKGTTVSVQNLFYTLPVRHKEFQRNIKKEYAKMVQVLQAYCIISAGIRVSCTNQLGQGKRQPVVCTSGSSGMKENIGSVFGQKQLQSLVPFVQLPPSDSVCEEYCLSACGTPQSPFRKSMFAEMEILGQFNLGFIVTKLKEDLFLVDQHAADEKYNFEMLQQHTVLQAQRLITPQTLNLTAVNEAVLIENLEIFRKNGFDFIIDEDAPVTERAKLISLPTSKNWTFGPQDIDELIFMLSDSPGVMCRPSRVRQMFASRACRKSVMIGTALSASEMKKLISHMGEMDHPWNCPHGRPTMRHIANLDVISQN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0009410 (response to xenobiotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: RNA polymerase II C-terminal domain phosphatase-like 2 (FCP-like 2) (EC 3.1.3.16) (ASI1-immunoprecipitated protein 4) (Carboxyl-terminal phosphatase-like 2) (AtCPL2) (CTD phosphatase-like 2) (Q5YDB5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Processively dephosphorylates 'Ser-5' but not 'Ser-2' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1). This promotes the activity of RNA polymerase II. Together with CPL1, required for male gametes fertility. Multifunctional regulator that modulates plant growth, stress, and phytohormones responses. Positive transcription regulator of genes involved in high salinity resistance and auxin mediated signaling pathway.
Subcellular location: Nucleus {ECO:0000269|PubMed:15388846}. Cytoplasm {ECO:0000269|PubMed:15388846}.
InterPro domains:
- IPR039189: CTD phosphatase Fcp1 (family) [35-420]
- IPR014720: Double-stranded RNA-binding domain (domain) [656-722]
- IPR036412: HAD-like superfamily (homologous_superfamily) [127-391]
- IPR023214: HAD superfamily (homologous_superfamily) [128-384]
- IPR004274: FCP1 homology domain (domain) [134-385]
Sequence:
MNRLGHKSVVYHGDLRLGELDVNHVSSSHEFRFPNDEIRIHHLSPAGERCPPLAILQTIASFAVRCKLESSAPVKSQELMHLHAVCFHELKTAVVMLGDEEIHLVAMPSKEKKFPCFWCFSVPSGLYDSCLRMLNTRCLSIVFDLDETLIVANTMKSFEDRIEALKSWISREMDPVRINGMSAELKRYMDDRMLLKQYIDNDYAFDNGVLLKAQPEEVRPTSDGQEKVCRPVIRLPEKNTVLTRIKPEIRDTSVLVKLRPAWEELRSYLTAKTRKRFEVYVCTMAERDYALEMWRLLDPEAHLISLKELRDRIVCVKPDAKKSLLSVFNGGICHPKMAMVIDDRMKVWEDKDQPRVHVVSAYLPYYAPQAETALVVPHLCVARNVACNVRGYFFKEFDESLMSSISLVYYEDDVENLPPSPDVSNYVVIEDPGFASNGNINAPPINEGMCGGEVERRLNQAAAADHSTLPATSNAEQKPETPKPQIAVIPNNASTATAAALLPSHKPSLLGAPRRDGFTFSDGGRPLMMRPGVDIRNQNFNQPPILAKIPMQPPSSSMHSPGGWLVDDENRPSFPGRPSGLYPSQFPHGTPGSAPVGPFAHPSHLRSEEVAMDDDLKRQNPSRQTTEGGISQNHLVSNGREHHTDGGKSNGGQSHLFVSALQEIGRRCGSKVEFRTVISTNKELQFSVEVLFTGEKIGIGMAKTKKDAHQQAAENALRSLAEKYVAHVAPLARETEKGPENDNGFLWESSEDVSNKGLEEEAPKENISEL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0016791 (phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0040007 (growth), GO:0048589 (developmental growth), GO:0009628 (response to abiotic stimulus), GO:0009719 (response to endogenous stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0006970 (response to osmotic stress), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0009733 (response to auxin)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Protein delta homolog 2 (DLK-2) (Endothelial cell-specific protein S-1) (Epidermal growth factor-like protein 9) (EGF-like protein 9) (Q8K1E3)
Organism: Mus musculus (Mouse)
Function: Regulates adipogenesis.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
InterPro domains:
- IPR051022: Notch Signaling and Cell Fate Determination (family) [25-262]
- IPR001881: EGF-like calcium-binding domain (domain) [89-248]
- IPR018097: EGF-like calcium-binding, conserved site (conserved_site) [174-236]
- IPR000152: EGF-type aspartate/asparagine hydroxylation site (ptm) [189-238]
- IPR000742: EGF-like domain (domain) [25-248]
- IPR013032: EGF-like, conserved site (conserved_site) [142-166]
Sequence:
MPSGCRCLNLVCLLCILGATSQPARADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGCQHGTCHQPWQCICHSGWAGKFCDKDEHICTSQSPCQNGGQCVYDGGGEYHCVCLPGFHGRGCERKAGPCEQAGFPCRNGGQCQDNQGFALNFTCRCLAGFMGAHCEVNVDDCLMRPCANGATCIDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCELVLPAPEPASVGTPQMPTSAVVVPATGPAPHSAGAGLLRISVKEVVRRQESGLGESSLVALVVFGSLTAALVLATVLLTLRAWRRGICPTGPCCYPAPHYAPARQDQECQVSMLPAGFPLSPDLPPEPGKTTAL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0005112 (Notch binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023057 (negative regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0010646 (regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0045746 (negative regulation of Notch signaling pathway), GO:0008593 (regulation of Notch signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0005769 (early endosome), GO:0043231 (intracellular membrane-bounded organelle), GO:0010008 (endosome membrane), GO:0098588 (bounding membrane of organelle), GO:0031982 (vesicle), GO:0012506 (vesicle membrane), GO:0030659 (cytoplasmic vesicle membrane), GO:0097708 (intracellular vesicle), GO:0031901 (early endosome membrane)
Protein: S-ribosylhomocysteine lyase (EC 4.4.1.21) (AI-2 synthesis protein) (Autoinducer-2 production protein LuxS) (P45578)
Organism: Escherichia coli (strain K12)
Function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
InterPro domains:
- IPR003815: S-ribosylhomocysteinase (LuxS) (family) [1-162]
- IPR011249: Metalloenzyme, LuxS/M16 peptidase-like (homologous_superfamily) [4-162]
- IPR037005: S-ribosylhomocysteinase (LuxS) superfamily (homologous_superfamily) [1-171]
Sequence:
MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELALPKEKLQELHI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0008374 (O-acyltransferase activity), GO:0016410 (N-acyltransferase activity), GO:0016407 (acetyltransferase activity), GO:0008080 (N-acetyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0007267 (cell-cell signaling), GO:0051606 (detection of stimulus), GO:0009607 (response to biotic stimulus), GO:0007154 (cell communication), GO:0040012 (regulation of locomotion), GO:0050794 (regulation of cellular process), GO:0009595 (detection of biotic stimulus), GO:2000145 (regulation of cell motility), GO:0009372 (quorum sensing), GO:0060245 (detection of cell density)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Single-stranded DNA-binding protein (SSB) (P66854)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Function: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
InterPro domains:
- IPR011344: Single-stranded DNA-binding protein (family) [1-156]
- IPR000424: Primosome PriB/single-strand DNA-binding (family) [1-104]
- IPR012340: Nucleic acid-binding, OB-fold (homologous_superfamily) [1-156]
Sequence:
MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGEREADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQMLESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0043933 (protein-containing complex organization), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly), GO:0051259 (protein complex oligomerization), GO:0051260 (protein homooligomerization), GO:0051262 (protein tetramerization), GO:0070206 (protein trimerization), GO:0070207 (protein homotrimerization), GO:0051289 (protein homotetramerization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Cytochrome P450 (Q86SK2)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004586}.
InterPro domains:
- IPR036396: Cytochrome P450 superfamily (homologous_superfamily) [13-351]
- IPR017972: Cytochrome P450, conserved site (conserved_site) [285-294]
- IPR001128: Cytochrome P450 (family) [26-343]
- IPR002401: Cytochrome P450, E-class, group I (family) [144-315]
- IPR050705: Cytochrome P450 3A (family) [25-347]
Sequence:
MDLIPNFAMETWVLVATSLVLLYIVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDGTVSGA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0036094 (small molecule binding), GO:0008289 (lipid binding), GO:0097159 (organic cyclic compound binding), GO:0043167 (ion binding), GO:0016491 (oxidoreductase activity), GO:0005496 (steroid binding), GO:0004497 (monooxygenase activity), GO:0043177 (organic acid binding), GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen), GO:0043168 (anion binding), GO:0005501 (retinoid binding), GO:0016709 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen), GO:0031406 (carboxylic acid binding), GO:0001972 (retinoic acid binding), GO:0033293 (monocarboxylic acid binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0009410 (response to xenobiotic stimulus), GO:0070887 (cellular response to chemical stimulus), GO:0006805 (xenobiotic metabolic process), GO:0071466 (cellular response to xenobiotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)