lokahq/bioreason-rl huggingface dataset:
Protein: Interleukin-1 (Q9PT12)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Function: Not known
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}. Lysosome {ECO:0000256|ARBA:ARBA00004371}. Secreted, extracellular exosome {ECO:0000256|ARBA:ARBA00004550}.
InterPro domains:
- IPR008996: Cytokine IL1/FGF (homologous_superfamily) [98-252]
- IPR000975: Interleukin-1 family (family) [36-253]
Sequence:
MEFESNCSLMKNTSASVAWSSKLPQGLDVEISHHPITLRCVANLIIAMERLNGGKGFTLGRDEGLLNFLLESAVEVLELESARTEASSRAAFSSKGEYECSVTDSENKCWVLNEGSMELHAIMLQGGSSYHKVHLNLSTYITPVPSETKARPVALGIKGSNLYLSCITSEGTPTLHLEEVADKEQLKSINHESDMVRFLFYKQDTGVDISTLESAHYRNWFISTALQQDNTKMVNMCQRATLNRNTTFTIQRHN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (signaling receptor activator activity), GO:0048018 (receptor ligand activity), GO:0005125 (cytokine activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0009893 (positive regulation of metabolic process), GO:0019222 (regulation of metabolic process), GO:0009892 (negative regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0010628 (positive regulation of gene expression), GO:0010629 (negative regulation of gene expression), GO:0010468 (regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Alpha-2-HS-glycoprotein (Fetuin-A) (B0JYN6)
Organism: Bos taurus (Bovine)
Function: Not known
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
InterPro domains:
- IPR001363: Proteinase inhibitor I25C, fetuin, conserved site (conserved_site) [32-149]
- IPR025760: Fetuin-A-type cystatin domain (domain) [27-256]
- IPR050735: Kininogen/Fetuin/Histidine-rich Glycoprotein (family) [1-269]
- IPR046350: Cystatin superfamily (homologous_superfamily) [27-238]
- IPR000010: Cystatin domain (domain) [23-249]
Sequence:
MKSFVLLFCLAQLWGCHSIPLDPVAGYKEPACDDPDTEQAALAAVDYINKHLPRGYKHTLNQIDSVKVWPRRPTGEVYDIEIDTLETTCHVLDPTPLANCSVRQQTQHAVEGDCDIHVLKQDGQFSVLFTKCDSSPDSAEDVRKLCPDCPLLAPLNDSRVVHAVEVALATFNAESNGSYLQLVEISRAQFVPLPVSVSVEFAVAATDCIAKEVVDPTKCNLLAEKQYGFCKGSVIQKALGGEDVRVTCTLFQTQPVIPQPQPDGAEAEAPSAVPDAAGPTPSAAGPPVASVVVGPSVVAVPLPLHRAHYDLRHTFSGVASVESSSGEAFHVGKTPIVGQPSIPGGPVRLCPGRIRYFKI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0032501 (multicellular organismal process), GO:0050793 (regulation of developmental process), GO:0001503 (ossification), GO:0051241 (negative regulation of multicellular organismal process), GO:0051239 (regulation of multicellular organismal process), GO:0051093 (negative regulation of developmental process), GO:2000026 (regulation of multicellular organismal development), GO:0030279 (negative regulation of ossification), GO:0030278 (regulation of ossification), GO:0070168 (negative regulation of biomineral tissue development), GO:0070167 (regulation of biomineral tissue development), GO:0030500 (regulation of bone mineralization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005576 (extracellular region), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043230 (extracellular organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0031982 (vesicle)
Protein: NAD(P)H quinone oxidoreductase PST3 (EC 1.6.5.2) (Flavodoxin-like protein PST3) (FLP PST3) (A0A1D8PT02)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
Subcellular location: Cell membrane {ECO:0000269|PubMed:26325183}; Peripheral membrane protein {ECO:0000269|PubMed:26325183}.
InterPro domains:
- IPR029039: Flavoprotein-like superfamily (homologous_superfamily) [1-199]
- IPR005025: NADPH-dependent FMN reductase-like domain (domain) [18-144]
- IPR008254: Flavodoxin/nitric oxide synthase (domain) [5-193]
- IPR010089: Flavoprotein WrbA-like (family) [4-193]
Sequence:
MAPKVAIIIYSLYHHIAQLAEEEKKGIEAAGGVADIYQVPETLSDDVLKLLHAPAKPNYPIATNDTLTGYDAYLFGIPTRFGNYPAQFKAFWDATGGLWAQGALAGKQAGIFVSTSGQGGGQETTAVNALSVLVHHGIIFVPLGYAKAFPLQTNLEEIHGGSPYGAGTFAGVDGSRQPTKLEKEIAFIQGKSFYETVSK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016651 (oxidoreductase activity, acting on NAD(P)H), GO:0016655 (oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor), GO:0003955 (NAD(P)H dehydrogenase (quinone) activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0006979 (response to oxidative stress), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0034599 (cellular response to oxidative stress), GO:0062197 (cellular response to chemical stress)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1) (P04692)
Organism: Rattus norvegicus (Rat)
Function: Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:7568216}. Note=Associates with F-actin stress fibers (PubMed:7568216). {ECO:0000269|PubMed:7568216}.
InterPro domains:
- IPR000533: Tropomyosin (family) [67-283]
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0051015 (actin filament binding), GO:0042802 (identical protein binding), GO:0008092 (cytoskeletal protein binding), GO:0046983 (protein dimerization activity), GO:0042803 (protein homodimerization activity), GO:0046982 (protein heterodimerization activity), GO:0003779 (actin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0003008 (system process), GO:0003012 (muscle system process), GO:0006936 (muscle contraction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015629 (actin cytoskeleton)
Protein: peptidoglycan lytic exotransglycosylase (EC 4.2.2.n1) (Murein hydrolase A) (Q9JPQ6)
Organism: Neisseria meningitidis
Function: Not known
InterPro domains:
- IPR005300: Lytic transglycosylase MltA, domain B (domain) [137-335]
- IPR026044: Membrane-bound lytic murein transglycosylase A (family) [1-441]
- IPR010611: 3D domain (domain) [359-430]
- IPR036908: RlpA-like domain superfamily (homologous_superfamily) [51-439]
Sequence:
MKKYLFRAALCGIAAAILAACQSKSIQTFPQPDTSVINGPGRPVGIPDPAGTTVGGGGAVYTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFERYFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKALVRIRQTGKNSGTIDNTGGTHTADLSQFPITARTTAIKGRFEGSRFLPYHTRNQINGGALDGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGKYMADKGYLKLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELTGSSNDGPVGALGTPLMGEYAGAVDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGKQKTTGYVWQLLPNGMKPEYRP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0061783 (peptidoglycan muralytic activity), GO:0016829 (lyase activity), GO:0016835 (carbon-oxygen lyase activity), GO:0016837 (carbon-oxygen lyase activity, acting on polysaccharides)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901575 (organic substance catabolic process), GO:0043170 (macromolecule metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0009057 (macromolecule catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:1901136 (carbohydrate derivative catabolic process), GO:0006022 (aminoglycan metabolic process), GO:0006026 (aminoglycan catabolic process), GO:0030203 (glycosaminoglycan metabolic process), GO:0006027 (glycosaminoglycan catabolic process), GO:0000270 (peptidoglycan metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0031975 (envelope), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030312 (external encapsulating structure), GO:0009279 (cell outer membrane), GO:0019867 (outer membrane), GO:0030313 (cell envelope)
Protein: Transmembrane protein, putative (DUF3317) (F4IPU5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477}.
InterPro domains:
- IPR024512: Small subunit of serine palmitoyltransferase-like (family) [1-52]
Sequence:
MNWVQRKIYLYNVTFGLYMLDWWERYLFNSLVLILMWFILYNGSRYFSELCKRHLS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0065009 (regulation of molecular function), GO:0050790 (regulation of catalytic activity), GO:0044093 (positive regulation of molecular function), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0048229 (gametophyte development), GO:0080090 (regulation of primary metabolic process), GO:0044087 (regulation of cellular component biogenesis), GO:0009555 (pollen development), GO:0010556 (regulation of macromolecule biosynthetic process), GO:1905038 (regulation of membrane lipid metabolic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0051338 (regulation of transferase activity), GO:0043085 (positive regulation of catalytic activity), GO:0019216 (regulation of lipid metabolic process), GO:0090153 (regulation of sphingolipid biosynthetic process), GO:0046890 (regulation of lipid biosynthetic process), GO:0051347 (positive regulation of transferase activity)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: RELA proto-oncogene, NF-kB subunit (E9PQS6)
Organism: Homo sapiens (Human)
Function: Not known
InterPro domains:
- IPR000451: NF-kappa-B/Dorsal (family) [4-208]
- IPR037059: Rel homology domain (RHD), DNA-binding domain superfamily (homologous_superfamily) [1-176]
- IPR008967: p53-like transcription factor, DNA-binding domain superfamily (homologous_superfamily) [9-187]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [177-208]
- IPR014756: Immunoglobulin E-set (homologous_superfamily) [182-208]
- IPR011539: Rel homology domain, DNA-binding domain (domain) [7-181]
- IPR030492: Rel homology domain, conserved site (conserved_site) [25-31]
- IPR030495: Transcription factor p65, RHD domain, N-terminal (domain) [10-178]
Sequence:
MDEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023056 (positive regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0010647 (positive regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0010646 (regulation of cell communication), GO:1902533 (positive regulation of intracellular signal transduction), GO:1902531 (regulation of intracellular signal transduction), GO:0043123 (positive regulation of I-kappaB kinase/NF-kappaB signaling), GO:0043122 (regulation of I-kappaB kinase/NF-kappaB signaling)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Tektin-4 (Q8WW24)
Organism: Homo sapiens (Human)
Function: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity). Contributes to normal sperm motility (By similarity).
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:36191189}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q149S1}. Note=Found in the abaxial (convex) surface of outer dense fibers in sperm flagella. {ECO:0000250|UniProtKB:Q149S1}.
InterPro domains:
- IPR048256: Tektin-like (family) [44-426]
- IPR000435: Tektins (family) [30-434]
Sequence:
MAQTVPPCELPCKEYDVARNTGAYTSSGLATASFRTSKYLLEEWFQNCYARYHQAFADRDQSERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDIAAMTNSLFIDRQKCMAHRTRYPTILQLAGYQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0007017 (microtubule-based process), GO:0032504 (multicellular organism reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0044706 (multi-multicellular organism process), GO:0060378 (regulation of brood size), GO:0048870 (cell motility), GO:0001539 (cilium or flagellum-dependent cell motility), GO:0007018 (microtubule-based movement), GO:0003341 (cilium movement), GO:0060285 (cilium-dependent cell motility), GO:0060294 (cilium movement involved in cell motility)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: T-box transcription factor mls-1 (Mesodermal lineage specification protein 1) (O17212)
Organism: Caenorhabditis elegans
Function: Probable transcription factor required for the cell fate specification of non-striated uterine muscle precursor cells. Furthermore, may function with the transcriptional corepressor unc-37.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.
InterPro domains:
- IPR046360: T-box transcription factor, DNA-binding domain (domain) [30-215]
- IPR008967: p53-like transcription factor, DNA-binding domain superfamily (homologous_superfamily) [31-210]
- IPR001699: T-box transcription factor (family) [29-209]
- IPR036960: T-box superfamily (homologous_superfamily) [17-210]
- IPR018186: Transcription factor, T-box, conserved site (conserved_site) [40-59]
Sequence:
MNRNFSIDAILARKPVEKRKQIITKDNCKFIRVFLQSSNLWRRFHNLGTEMIVTKSGRRMFPTLSVIIAGLDPVKSYVVMVDLECIEMKRFRYSFHQSKWISTGPGESELPSRMFVHTDSPARGAHWMRAPVSFDKMKLTNNQLDNNGHIIVNSMHKYRPRVHIIEQDDSQKRHTFSFEETEFIAVTAYQNHRITSLKIESNPFAKGFRECEVQGIEMNSVGGMTGGPAFQSVFPLIFPYFANLASNMNVNK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding), GO:0000977 (RNA polymerase II transcription regulatory region sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009790 (embryo development), GO:0010171 (body morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0010172 (embryonic body morphogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Leucine zipper putative tumor suppressor 3 (ProSAP-interacting protein 1) (ProSAPiP1) (Q8K1Q4)
Organism: Rattus norvegicus (Rat)
Function: May be involved in promoting the maturation of dendritic spines, probably via regulating SIPA1L1 levels at the postsynaptic density of synapses.
Subcellular location: Synapse {ECO:0000269|PubMed:27252646}. Postsynaptic density {ECO:0000269|PubMed:16522626, ECO:0000269|PubMed:27252646}. Cell projection, dendritic spine {ECO:0000269|PubMed:16522626}. Cell projection, dendrite {ECO:0000269|PubMed:16522626}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:16522626}. Note=Rather found at excitatory than inhibitory synapses (PubMed:27252646). {ECO:0000269|PubMed:16522626, ECO:0000269|PubMed:27252646}.
InterPro domains:
- IPR045329: Leucine zipper putative tumor suppressor (family) [31-542]
Sequence:
MAPADLASEGPKLEDPPAPHLFGKCPSGLIMANVETLPVRADPGRDPLLAFAPRPAELGPPDPRLTMGSVGGGVTHAQEFPMKSVGTRTGGGGSQGSFPGPRSSGSGTNRERPGPGRYPSEDKVLANSLYLNGELRGSDHTDVCGNVVGSSGGSSSSGGSDKAPPQYREPNHPPKLLTTSGKLDQCSEPLVRPSAFKPVVPKNFHSMQNLCPPQTNGTPEGRQGPAGLKGGLEKSRTMTPAGGSGGGGLSDSGRNSLTSLPTYSSSYSQHLAPLSASTSHINRIGTPGYSSGGGGGGSGYQDLGTSDSGRASSKSGSSSSMGRSGHLGSGEGGNGGLPFAACSPPSPSALIQELEERLWEKEQEVAALRRSQEQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVARRAQRAQQGLQLQVLRLQQDKKQLQEEAAQLIRQREELEDKVAACQKEQADFLPRMEETKWEVCQKAGEISLLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQLLSLRDSFGSKQASLELSEGELPPACLKPALTPVDLVEPQEALASCESDEAKMRRQAGVAAAASLVSVDGEVDAGGEGGTRALRREVGRLQAELAAERRARERQGASFAEERRVWLEEKEKVIEYQKQLQLSYVEMYQRNQQLERRLRERGAAGGSRTPTPQHGEEEKAWTPSRLERIESTEI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0009719 (response to endogenous stimulus), GO:0042221 (response to chemical), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0008284 (positive regulation of cell population proliferation), GO:0042127 (regulation of cell population proliferation), GO:0043627 (response to estrogen)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0030054 (cell junction), GO:0098794 (postsynapse), GO:0045202 (synapse), GO:0099572 (postsynaptic specialization), GO:0098984 (neuron to neuron synapse), GO:0014069 (postsynaptic density), GO:0032279 (asymmetric synapse)