lokahq/bioreason-rl huggingface dataset:
Protein: LD11117p (Lipophorin receptor 2, isoform E) (Q7YU01)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
InterPro domains:
- IPR011042: Six-bladed beta-propeller, TolB-like (homologous_superfamily) [610-868]
- IPR009030: Growth factor receptor cysteine-rich domain superfamily (homologous_superfamily) [511-919]
- IPR001881: EGF-like calcium-binding domain (domain) [523-604]
- IPR018097: EGF-like calcium-binding, conserved site (conserved_site) [564-587]
- IPR000152: EGF-type aspartate/asparagine hydroxylation site (ptm) [538-589]
- IPR000033: LDLR class B repeat (repeat) [630-866]
- IPR051221: Low-density lipoprotein receptor-related (family) [192-946]
- IPR023415: Low-density lipoprotein (LDL) receptor class A, conserved site (conserved_site) [248-522]
- IPR000742: EGF-like domain (domain) [235-919]
- IPR036055: LDL receptor-like superfamily (homologous_superfamily) [190-518]
- IPR002172: Low-density lipoprotein (LDL) receptor class A repeat (repeat) [192-524]
- IPR026823: Complement Clr-like EGF domain (domain) [544-567]
Sequence:
MATTCMPHFTEYFQTTTQSELTTNESANSRSSSSSSGCREPSKTSGFFYSASTHYQSKVQQLISFSFTSSFHLLFITCILSISKFCNAAAVNAAHVTAATPTASEIMHNLSGSALLERLKASTLGPTLDQLKHLAPAAANSISPGTGSGMGIGMGHFGSSINSVLNGNPLKFLNVSGKIGTPLDISLGLSNYCDEKQFQCSTGECIPIRFVCDGSSDCPDHSDERLEECKFTESTCSQEQFRCGNGKCIPRRWVCDRENDCADGSDESTSQCRSHTCSPEEFACKSGEGECIPLSWMCDQNKDCRDGSDEAQCNRTCRSDEFTCGNGRCIQNRFKCDDDDDCGDGSDEKNCGEKAKCGSNFFACKSGPCIPNQWVCDGDSDCRNGEDEMQNCTVSLLNFCQAGEFQCSDRITCLHKSWVCDGEADCPDGEDESQSNCLKVSCRPDQFQCNDQSCIAGHLTCNGKRDCADGSDEIMCDISATPRTCNATTEFDCGGGLCIPNAKVCNRRKDCPNGEDEPAGKCGINECSSKNGGCMHQCVNLEVGYRCECHDGYKLGADQHTCVDIDECETPGICSQVCVNEIGAFKCECEAGYMRLLKNHTRCKASEGHASLLLARRHDIRKIALDRPEMTSIVNSTKAATALDFVFRTGMIFWSDVATQSIYKAPIDEGNDRTVVLTKSSVTSDGLAVDWIYNHVYFTDTHKCTIELTNFEGSMGKVLVKDSLDIPRSIALDPIEGWMYWSDWGASPRIERAGMDGTHRTAIITYDVKWPNGITLDLVQKRLYWVDGKLNTISSSNYDGSQRHQVLYSGEYLRHPFSITTFEDYVYWTDWDKQAVFKANKFNGMDVEPVTATHMLEHPMVVHVYHPYRQPDGVNHCQSVNGHCSHLCLPAPRINERSPRISCACPTGLKLMPDGLMCVEDLGIPTVRPTAPMHRTIEQSSNSTTKLPQDGYSETPVETKTGNNRTDTSNQVHKSDAESENDYVEIALHVIASLAGTALVASVIYVVYRRCTRAVNSMNFENPVYHKTTEDHFSLEKNGTPHIYAAANDEEAVNPLFKSGTECV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0071814 (protein-lipid complex binding), GO:0071813 (lipoprotein particle binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0051050 (positive regulation of transport), GO:1905954 (positive regulation of lipid localization), GO:0032879 (regulation of localization), GO:0032370 (positive regulation of lipid transport), GO:1905952 (regulation of lipid localization), GO:0051049 (regulation of transport), GO:0032368 (regulation of lipid transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Leucine-rich repeat and IQ domain-containing protein 3 (Leucine-rich repeat-containing protein 44) (A6PVS8)
Organism: Homo sapiens (Human)
Function: Not known
InterPro domains:
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [28-174]
- IPR052859: Leucine-rich repeat and IQ domain-containing protein (family) [2-612]
- IPR001611: Leucine-rich repeat (repeat) [73-94]
Sequence:
MFHGTVTEELTSHEEWSHYNENIREGQKDFVFVKFNGLHLKSMENLQSCISLRVCIFSNNFITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNGLKNLKLLYLHDNGFAKLKNICVLSACPTLIALTMFDCPVSLKKGYRHVLVNSIWPLKALDHHVISDEEIIQNWHLPERFKACNHRLFFNFCPALRKGTTYEEEINNIKHITSKINAILAHNSPVLIVQRWIRGFLVRKNLSPVFFHKKKQQEKIIRGYEAKWIYITKGYEDKLLKDLFFKPETNIKGKLAYWKHNIYYPVDLKNSSEHRKHVSSILCELKPKDLGMKSKTSRHLIQKGQESEDEIVDEKLDTSFRISVFKLPIYTSGSLKNNAVLREKKQHFFPAYPQPIYTTHPKPIIKKDIRLERSMKEFFAPQRAGMKLRTFSDIDKYYTEQKKQEYHKEKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETIQNSLRQVWQNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEKNEAVLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYKRHCEEKFVMDMIAFEKACERLQDAKTKVAIVKTNLDFKVPNGLIK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0030030 (cell projection organization), GO:0044782 (cilium organization), GO:0120036 (plasma membrane bounded cell projection organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0034451 (centriolar satellite), GO:0043229 (intracellular organelle), GO:0005813 (centrosome), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015630 (microtubule cytoskeleton)
Protein: Uncharacterized oxidoreductase Rv0484c (EC 1.-.-.-) (P9WGR5)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Not known
InterPro domains:
- IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [6-234]
- IPR002347: Short-chain dehydrogenase/reductase SDR (family) [9-187]
Sequence:
MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASRRATHPVR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0071554 (cell wall organization or biogenesis), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0044036 (cell wall macromolecule metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044085 (cellular component biogenesis), GO:0006629 (lipid metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0042546 (cell wall biogenesis), GO:0006082 (organic acid metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:0006631 (fatty acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0016053 (organic acid biosynthetic process), GO:0070589 (cellular component macromolecule biosynthetic process), GO:0009273 (peptidoglycan-based cell wall biogenesis), GO:0034645 (cellular macromolecule biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0044038 (cell wall macromolecule biosynthetic process), GO:0006633 (fatty acid biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0071766 (Actinobacterium-type cell wall biogenesis), GO:0046394 (carboxylic acid biosynthetic process), GO:0072330 (monocarboxylic acid biosynthetic process), GO:0032787 (monocarboxylic acid metabolic process), GO:0030497 (fatty acid elongation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: T-cell-specific surface glycoprotein CD28 (CD antigen CD28) (P31041)
Organism: Mus musculus (Mouse)
Function: Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:27460989}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P10747}.
InterPro domains:
- IPR008093: T cell antigen CD28 (family) [126-217]
- IPR013106: Immunoglobulin V-set domain (domain) [26-123]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [22-137]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [19-146]
- IPR040216: Cytotoxic T-lymphocyte protein 4/CD28 (family) [3-214]
Sequence:
MTLRLLFLALNFFSVQVTENKILVKQSPLLVVDSNEVSLSCRYSYNLLAKEFRASLYKGVNSDVEVCVGNGNFTYQPQFRSNAEFNCDGDFDNETVTFRLWNLHVNHTDIYFCKIEFMYPPPYLDNERSNGTIIHIKEKHLCHTQSSPKLFWALVVVAGVLFCYGLLVTVALCVIWTNSRRNRLLQSDYMNMTPRRPGLTRKPYQPYAPARDFAAYRP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0001775 (cell activation), GO:0045321 (leukocyte activation), GO:0006955 (immune response), GO:0051240 (positive regulation of multicellular organismal process), GO:0031294 (lymphocyte costimulation), GO:0002684 (positive regulation of immune system process), GO:0050794 (regulation of cellular process), GO:0002682 (regulation of immune system process), GO:0051239 (regulation of multicellular organismal process), GO:0048522 (positive regulation of cellular process), GO:0002696 (positive regulation of leukocyte activation), GO:0030155 (regulation of cell adhesion), GO:0002694 (regulation of leukocyte activation), GO:0045785 (positive regulation of cell adhesion), GO:0050865 (regulation of cell activation), GO:0046649 (lymphocyte activation), GO:0050867 (positive regulation of cell activation), GO:0031295 (T cell costimulation), GO:0051251 (positive regulation of lymphocyte activation), GO:0022409 (positive regulation of cell-cell adhesion), GO:0022407 (regulation of cell-cell adhesion), GO:0042110 (T cell activation), GO:0051249 (regulation of lymphocyte activation), GO:0050870 (positive regulation of T cell activation), GO:0050863 (regulation of T cell activation), GO:1903037 (regulation of leukocyte cell-cell adhesion), GO:1903039 (positive regulation of leukocyte cell-cell adhesion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098552 (side of membrane), GO:0009986 (cell surface), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0009897 (external side of plasma membrane), GO:0005886 (plasma membrane)
Protein: Aspartic proteinase yapsin-1 (EC 3.4.23.-) (O59774)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Cleaves at paired basic residues.
Subcellular location: Endoplasmic reticulum membrane; Single-pass membrane protein. Secreted, cell wall.
InterPro domains:
- IPR033121: Peptidase family A1 domain (domain) [67-410]
- IPR021109: Aspartic peptidase domain superfamily (homologous_superfamily) [52-422]
- IPR001461: Aspartic peptidase A1 (family) [46-408]
Sequence:
MRIWILIFFSFIKLVSSLQYTGNGVLALDFVAKTFPNQENQLEKRDYTYSPSGITSFPLDLQSYTYYTTTLSIGRPSISYTVAIDLDMPYTWLTYYNVMAFNPAYLGIVNSGTQWSTDELRYFLCKKESDSCYFGNASSSFHFVTSPSTFFIRYDDNITVAGINVQDSLSYSHYQALPDFQFGITLKEYVPSSMLPYKGVLGLAASTEINSIDYSDSISSFSPPTFLEQLVKEDILAYPAFSMYLDNQGNGSLLLGAVDTSKYQGQFVALKQTKLTHYAVSIYSVQFLNSTFFSNYSIITDAYFQTRETYIYLPAELAYSVMDNAGAYLSEGYFALNCDEIDLEAALIFQFGCNSTIKVPISLLVIGQVSNICLLGIRPSTDSEIVLGLLFFRNAYTFYHQSQKMIAIGQAFYNATSNLSAIVDQHIPGALTCSQYPTSVASTQLVQTSHFTSTSLSAVNISESVVYSYTSSSSMPSSAIPSFNISLISQNAVANAGNSFSPLSAMVIMMMSAVFLGLGII
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0004175 (endopeptidase activity), GO:0070001 (aspartic-type peptidase activity), GO:0004190 (aspartic-type endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0071554 (cell wall organization or biogenesis), GO:0071555 (cell wall organization), GO:0016043 (cellular component organization), GO:0071852 (fungal-type cell wall organization or biogenesis), GO:0045229 (external encapsulating structure organization), GO:0031505 (fungal-type cell wall organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098552 (side of membrane), GO:0009986 (cell surface), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030312 (external encapsulating structure), GO:0009897 (external side of plasma membrane), GO:0005618 (cell wall), GO:0005886 (plasma membrane), GO:0009277 (fungal-type cell wall)
Protein: DDHD domain containing 2 (E9PK57)
Organism: Homo sapiens (Human)
Function: Not known
InterPro domains:
- IPR004177: DDHD domain (domain) [1-151]
- IPR058055: PA-PLA1 (family) [7-153]
Sequence:
MVVPGVEFEPMLIPHHKGRKRMHLELREGLTRMSMDLKNNLLGSLRMAWKSFTRAPYPALQASETPEETEAEPESTSEKPSDVNTEETSVAVKEEVLPINVGMLNGGQRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTVLLVLKEIYQTQGIFLDQPLQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0010256 (endomembrane system organization), GO:0007030 (Golgi organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0034451 (centriolar satellite), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0005813 (centrosome), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015630 (microtubule cytoskeleton)
Protein: Probable solute-binding protein (Q9I2T3)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Not known
InterPro domains:
- IPR039424: Solute-binding protein family 5 (family) [2-592]
- IPR000914: Solute-binding protein family 5 domain (domain) [114-507]
- IPR030678: Peptide/nickel binding protein, MppA-type (family) [1-606]
Sequence:
MRRLSFLILGLAVSLPSFAAITQSHGYAQFGTLKYPANFQHFDWTNPDAPKGGTLRLMASGSFDTLNPYTLKGTSPIGTGDFLQYGVNELNEPLMVGTGLYDPSGDEPASSYGLIAKSVEYAENRSWVVFNLRPEARFHDGRPITASDVAFSYRTLVKQGHPMYRTYLQEVKRVDILTPHRVRFVLRRSGNPLLILRLGELPVLPQHYWKDRDFRATTFTAPLGSGPYRIVEVDPGRRLVFERVKGWWGEKLPVNRGKYNFDRVVVDFYRDNGVAFEAFKAGEFDFYIEHQAKNWLNNYRFPAVLRGDVIRTEIPHQIPSQTQALFMNTRRAVFKERALRQALGEMFDFEWTNRALFSNSYLRSRSYYPNSEFAASGVPEGQEWLYLSPYRKQLPAQLFKQPFSLPTTEGRGIPRETLRHALGLLADAGWKLSGDRLLNKKGEPLRFEILLVNPSLERILQPYRENLASIGIDARLRTVDRAQYKQRLDQFDYDMILMTLPQTLSPGLEQWQYFHSSQVKVKGSKNYAGIANPVVDAMLNRLLGAHSRDEQVAAARALDRTLLWQYYSIPNWYLNSHRLAYRNRFAFVATPPYTLGLRAWWQKNLETSR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0140657 (ATP-dependent activity), GO:0042626 (ATPase-coupled transmembrane transporter activity), GO:0022857 (transmembrane transporter activity), GO:0140359 (ABC-type transporter activity), GO:0042887 (amide transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0015399 (primary active transmembrane transporter activity), GO:1904680 (peptide transmembrane transporter activity), GO:0035673 (oligopeptide transmembrane transporter activity), GO:0071916 (dipeptide transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0071705 (nitrogen compound transport), GO:0015833 (peptide transport), GO:0042886 (amide transport), GO:0006857 (oligopeptide transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0031975 (envelope), GO:0098796 (membrane protein complex), GO:0042597 (periplasmic space), GO:1990351 (transporter complex), GO:0098797 (plasma membrane protein complex), GO:0030313 (cell envelope), GO:1902495 (transmembrane transporter complex), GO:0005886 (plasma membrane), GO:0030288 (outer membrane-bounded periplasmic space), GO:0098533 (ATPase dependent transmembrane transport complex), GO:0043190 (ATP-binding cassette (ABC) transporter complex)
Protein: Protein atp11, mitochondrial (P87127)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Essential for the assembly of the mitochondrial F1-F0 complex. May interact with the alpha and/or beta subunits of F1-ATPase (By similarity).
Subcellular location: Mitochondrion {ECO:0000250}.
InterPro domains:
- IPR010591: ATP11 (family) [33-285]
Sequence:
MLPIWKLPVNHLLCHSFKSIPRTSAYAVRFAHHTSNNDDLEVKKNTVYERYERKLKSKAEELHMPVTNLLKKGQTKEREHVIPKKSFSAKKSLVGQNAKKSDLSGLNRYIDVEKIKELPTSTIEKLWRARNIGDDILSACIPKEIYEKMLSRARMYPYFVLPLPRGDKGIESHFLQWNFPNKNEAHLLVTSLLEYKLKGSYAAPHTIMLHFADLLNLKGITLMRCQFEPKKLSANDVQLLVLAIQKFYNASENTPLGKERLALLAAFSKGADFDLHKVATHMDMLE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0006996 (organelle organization), GO:0043933 (protein-containing complex organization), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly), GO:0007005 (mitochondrion organization), GO:0070071 (proton-transporting two-sector ATPase complex assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Adenylyl cyclase) (Q57VY0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
InterPro domains:
- IPR057399: Receptor-type adenylate cyclase GRESAG 4.1/3, periplasmic binding protein-like domain 1 (domain) [153-295]
- IPR029787: Nucleotide cyclase (homologous_superfamily) [886-1115]
- IPR001054: Adenylyl cyclase class-3/4/guanylyl cyclase (domain) [719-1097]
- IPR028082: Periplasmic binding protein-like I (homologous_superfamily) [98-378]
- IPR057398: Receptor-type adenylate cyclase GRESAG 4.1/3, periplasmic binding protein-like domain 2 (domain) [449-815]
- IPR050697: Adenylyl/Guanylyl Cyclase Class-3/4 (family) [16-1200]
Sequence:
MTSLLSKLSLPLLQLLFLLLSFSTTGRAEDNTTINVLSLMYSPDVQEVEVDSLNAGFDASLTARGWKTNSKARVSFIRPPSYDTPVAEFFESVVKESEGKLMIVFGPFGGPNTMWVKGELSKHGAVSFGPLAFSTEVREWDPHLYFISVEPNAELLALFRYAVVFLGLPRVGITYLKGTPSGEALYEFALEISSMMGHELCGAFAAAGGVGADEDALAAEWNQFVETRPQAVLLFAPVRNPATEWFIGRIVKDERTRQMYVLAPSTSQGPLIRTWRDALYASNVSLNDGQLIITGTIPPSNLLTLASVRRFREEMDNHLKSNSEWGGFSKPPHFSTDEAISDLMMTGWLTGEILSQALHSTDVLTDRTAFMDSLYRQRRYVVDDLVVGDYGNECGEFASMQGAMCNCNQGGSAVYMKEVVDGFRIEPLQRGFLAWGASQCSSRDVKISIPLSGFVMHLSDYFFSYRSAKRWYEGVSSAPVIRDDFGEDILHFDVLPLSTQMGVIALEALLNMREIVIIYGAVDEDILELPGPVFVDPLLLYPRINRFNRNVLLLSPTVRQQLYVLAMHLSNASTGAVSAAIRSKRAEVIGDVLNKSLMTFDVALKSMLLLKESDTLVDHLPSSGDVVAIGLTPPDAHAIAQYLQSRNDRRVYVLFSEVAQLYDEFVEAFNATPAAVVSASRLVFATNLPHWADKNTESDTVAMFHAYNPRESTWTPLRLRGFATARLLRSIVPRMKRISPSLLVDFFYTESNIRVDDMHYGPYSDVECVKGRVTAANRCETNFGAGNISVWSMSRVLDPRVPVLSRGVTPSLEYAVMDESSLSPSQLAGIIVGSVFFVALAIALCVLLCLFVRVRGQRDTVPKSSSDLVTFINDSEVCVPMFEMLRGGECGVVTIVCTDIESSTAQWSTHPELMPDAVLAHHTMIRSLIMQYGCYEVKTVGDSFMIACRSTSTAVELASDIQRSFLQHCWGTTVFDDFYRNSEMQKAEDDDHYIPPSARLDPEVYRQLWNGLRVRIGIHTGLCDIRHDEVTKGYDYYGRTPNMAARTESVTNGGQVLLTYAAYMSLSTEERDQLDATSLGPVALRGVPEPIVMYQLNAVPGRAFTGLRLDRGFYFDEDVENFSFSSNSLSFDSLKLSGSAQTISDALHSLLSTFKPPQRERLLALYCERWNVPLPMGGSYAWDDAYCEEVIRRIAVKVGPFVGRYAS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0046983 (protein dimerization activity), GO:0042803 (protein homodimerization activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0035556 (intracellular signal transduction), GO:0019932 (second-messenger-mediated signaling), GO:0019935 (cyclic-nucleotide-mediated signaling), GO:0019933 (cAMP-mediated signaling)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0097542 (ciliary tip), GO:0043227 (membrane-bounded organelle), GO:0120025 (plasma membrane bounded cell projection), GO:0005929 (cilium)
Protein: Cytochrome c2 (P86321)
Organism: Afifella marina (Rhodobium marinum) (Rhodopseudomonas marina)
Function: Cytochrome c2 is found mainly in purple, non-sulfur, photosynthetic bacteria where it functions as the electron donor to the oxidized bacteriochlorophyll in the photophosphorylation pathway. However, it may also have a role in the respiratory chain and is found in some non-photosynthetic bacteria.
Subcellular location: Periplasm {ECO:0000269|PubMed:20697695}.
InterPro domains:
- IPR009056: Cytochrome c-like domain (domain) [4-107]
- IPR036909: Cytochrome c-like domain superfamily (homologous_superfamily) [1-107]
- IPR002327: Cytochrome c, class IA/ IB (family) [7-106]
Sequence:
QXGDLVAAGKKVYRQCHACHSVGEGAKNRVGPEQNNLFGRVAGSLPDFRYSKAMKSAGENGLVWTDKSLHEYLKNPRAYVPKTKMIFAGLKKPEDIDAVVAYLKTFDTDGMPDPDASTYTPPNG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0009055 (electron transfer activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006091 (generation of precursor metabolites and energy), GO:0015979 (photosynthesis), GO:0022900 (electron transport chain), GO:0019684 (photosynthesis, light reaction), GO:0009767 (photosynthetic electron transport chain)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0042597 (periplasmic space)