lokahq/bioreason-rl huggingface dataset:
Protein: 2-carboxy-1,4-naphthoquinone phytyltransferase, chloroplastic (EC 2.5.1.130) (1,4-dihydroxy-2-naphthoate phytyltransferase) (1,4-dihydroxy-2-naphthoate polyprenyltransferase) (Protein ABERRANT CHLOROPLAST DEVELOPMENT 4) (menA-like protein) (AtMENA) (Q0WUA3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4-naphthoquinone.
Subcellular location: Plastid, chloroplast membrane {ECO:0000269|PubMed:15686525}; Multi-pass membrane protein {ECO:0000269|PubMed:15686525}.
InterPro domains:
- IPR026046: UbiA prenyltransferase domain containing protein 1 (family) [60-382]
- IPR000537: UbiA prenyltransferase (family) [101-357]
- IPR011937: 2-carboxy-1,4-naphthoquinone phytyltransferase (family) [74-379]
Sequence:
MVNFVSLCDIKYGFVPKNSTDLFVKRKIHKLPSRGDVITRLPVFGSNARENLNAKPRRNLRVRPIFCKSYGDAAKVYQEEEIPRAKLIWRAIKLPMYSVALVPLTVGASAAYLETGLFLARRYVTLLLSSILIITWLNLSNDVYDFDTGADKNKMESVVNLVGSRTGTLAAAITSLALGVSGLVWTSLNASNIRAILLLASAILCGYVYQCPPFRLSYQGLGEPLCFAAFGPFATTAFYLLLGSSSEMRHLPLSGRVLSSSVLVGFTTSLILFCSHFHQVDGDLAVGKYSPLVRLGTEKGAFVVRWTIRLLYSMLLVLGLTRILPLPCTLMCFLTLPVGNLVSSYVEKHHKDNGKIFMAKYYCVRLHALLGAALSLGLVIAR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups), GO:0004659 (prenyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0042180 (cellular ketone metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901576 (organic substance biosynthetic process), GO:0044283 (small molecule biosynthetic process), GO:1901661 (quinone metabolic process), GO:0042181 (ketone biosynthetic process), GO:0006743 (ubiquinone metabolic process), GO:1901663 (quinone biosynthetic process), GO:0006744 (ubiquinone biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Primase-associated factor LEF-2 (P41418)
Organism: Autographa californica nuclear polyhedrosis virus (AcMNPV)
Function: Plays an essential role in viral DNA replication. Does not seem to participate in the initiation step but is rather important for the amplification of DNA. Also required for expression from the vp39 and polh promoters.
Subcellular location: Virion {ECO:0000269|PubMed:20219928}. Host nucleus {ECO:0000269|PubMed:20219928}. Host cytoplasm {ECO:0000269|PubMed:20219928}. Note=Colocalizes with the active viral DNA replication sites in the nucleus of infected cells. {ECO:0000269|PubMed:9060674}.
InterPro domains:
- IPR004283: Late expression factor 2 (family) [7-171]
Sequence:
MANASYNVWSPLIRASCLDKKATYLIDPDDFIDKLTLTPYTVFYNGGVLVKISGLRLYMLLTAPPTINEIKNSNFKKRSKRNICMKECVEGKKNVVDMLNNKINMPPCIKKILNDLKENNVPRGGMYRKRFILNCYIANVVSCAKCENRCLIKALTHFYNHDSKCVGEVMHLLIKSQDVYKPPNCQKMKTVDKLCPFAGNCKGLNPICNY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0016032 (viral process), GO:0019079 (viral genome replication), GO:0019058 (viral life cycle)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0033643 (host cell part), GO:0043657 (host cell), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0033647 (host intracellular organelle), GO:0030430 (host cell cytoplasm), GO:0033648 (host intracellular membrane-bounded organelle), GO:0042025 (host cell nucleus)
Protein: Probable transport accessory protein MmpS2 (P9WJT3)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Not known
Subcellular location: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000255}.
InterPro domains:
- IPR038468: Transport accessory protein MmpS, C-terminal (homologous_superfamily) [57-145]
- IPR008693: Transport accessory protein MmpS (family) [8-144]
Sequence:
MISVSGAVKRMWLLLAIVVVAVVGGLGIYRLHSIFGVHEQPTVMVKPDFDVPLFNPKRVTYEVFGPAKTAKIAYLDPDARVHRLDSVSLPWSVTVETTLPAVSVNLMAQSNADVISCRIIVNGAVKDERSETSPRALTSCQVSSG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030234 (enzyme regulator activity), GO:0005515 (protein binding), GO:0140678 (molecular function inhibitor activity), GO:0061134 (peptidase regulator activity), GO:0004857 (enzyme inhibitor activity), GO:0061135 (endopeptidase regulator activity), GO:0030414 (peptidase inhibitor activity), GO:0004866 (endopeptidase inhibitor activity), GO:0004867 (serine-type endopeptidase inhibitor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response), GO:0052553 (modulation by symbiont of host immune response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Stevor (C0H5N4)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Not known
InterPro domains:
- IPR006374: Variant surface antigen Stevor (family) [1-300]
Sequence:
MYYLKMLLFTFLINTLVLQHYENYLNNHYNVSLIQNNTKRTTIHSRLLAQTKNHNPHYHNDPELKEIIDKMNEEAIKKYQQTHDPYKQLKDVVEKNGTKYTGGNDVEPMSTLEKELLETYEETFGNKSDMLKLGKYKNDDDKSDDSSSCGCTNINNMKLAKTKGRDKYLKHLKGRCTRGIYISSLTTVILTTIALHTAKAAALAKFVESAKTCASYMTIFNMLNAGNLNTAIQAGGGICTSAYSDIVLPAANAALSAIYPCGIAALVLLILTVVLIILYIWLYRRRKRSWKHECKKHLCK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0044403 (biological process involved in symbiotic interaction), GO:0035821 (modulation of process of another organism), GO:0044068 (modulation by symbiont of host cellular process), GO:0051701 (biological process involved in interaction with host), GO:0020013 (modulation by symbiont of host erythrocyte aggregation), GO:0044003 (modulation by symbiont of host process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0043657 (host cell), GO:0033643 (host cell part), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0030430 (host cell cytoplasm), GO:0033655 (host cell cytoplasm part), GO:0020036 (Maurer's cleft)
Protein: Solute carrier family 17 member 3 (A0A0G2JY28)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
InterPro domains:
- IPR011701: Major facilitator superfamily (family) [104-353]
- IPR036259: MFS transporter superfamily (homologous_superfamily) [99-417]
- IPR050382: Major Facilitator Superfamily Sodium/Anion Cotransporter (family) [105-413]
Sequence:
MATVVELSPTSEQCEFVLGLPVNKKTPPRKVPSLCSMRYSIAFIAHICNFTLIAQNSIISITMVAMVNNTDQPSHLNSSTEWFPDGLNGDQHEASKHLSIKGAGYGGQFALWQKWAPPNERSRLCSIAMSGMILGIFAVLLVGGIISEALGWPFVFYIFGSIGVVCCLLWLILVYDDPVSHPWISSPEKEYILSSLDQQFNSEEQPLPIKAMLKSLPLWSMCLCSMTHQWLVNTLIIYTPTYISSVFKVNIRDNGLLSSLPFFVAWVIGILGGLLADFLLSKNFRLITVRKIITILGNTPPAALVVALPYVQSSYIATTTFLTLSCGLSPLCQSGVYINALDIAPRYASLLMGTSRGLAHSSAVMVPIVAGFFLNQDSEFGWRNFFFVLFAINLFGLIIYLVFAKADIQEWARERKLTRL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0022853 (active monoatomic ion transmembrane transporter activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0015081 (sodium ion transmembrane transporter activity), GO:0015291 (secondary active transmembrane transporter activity), GO:0015293 (symporter activity), GO:0015294 (solute:monoatomic cation symporter activity), GO:0046873 (metal ion transmembrane transporter activity), GO:0015370 (solute:sodium symporter activity), GO:0005436 (sodium:phosphate symporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0006811 (monoatomic ion transport), GO:0015698 (inorganic anion transport), GO:0006812 (monoatomic cation transport), GO:0006817 (phosphate ion transport), GO:0030001 (metal ion transport), GO:0006814 (sodium ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0010008 (endosome membrane), GO:0098588 (bounding membrane of organelle), GO:0031982 (vesicle), GO:0030659 (cytoplasmic vesicle membrane), GO:0012506 (vesicle membrane), GO:0097708 (intracellular vesicle)
Protein: Catalase (EC 1.11.1.6) (Q2U962)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Function: Not known
InterPro domains:
- IPR029062: Class I glutamine amidotransferase-like (homologous_superfamily) [549-747]
- IPR018028: Catalase, mono-functional, haem-containing (family) [40-530]
- IPR020835: Catalase superfamily (homologous_superfamily) [22-553]
- IPR024712: Catalase, mono-functional, haem-containing, clade 2 (family) [7-742]
- IPR010582: Catalase immune-responsive domain (domain) [459-523]
- IPR011614: Catalase core domain (domain) [44-434]
- IPR002226: Catalase haem-binding site (binding_site) [377-385]
- IPR024708: Catalase active site (active_site) [83-99]
- IPR041399: Large catalase, C-terminal domain (domain) [567-702]
- IPR043156: Catalase, mono-functional, haem-containing, clade 2, helical domain (homologous_superfamily) [455-548]
Sequence:
MANIVAGGLHKVQEAVQGAASKDKKLVDLAPDTHNVQSSKEPLTTDHGVRISDTDHWLKEVNDNHTGPMMLEDQIAREKIHRFDHERIPERVVHARGTAAFGNFKLHESAEDVSYAGILTDTSRNTPVFLRFSTVQGSKGSADTVRDVRGFAVKFYTDEGNWDLVGNNIPVFFIQDAIKFPDFVHAVKPEPHNEVPQAQTAHNNFWDFVYLHPEATHMFMWAMSDRAIPRSYRMMQGFGVNTFSLINKEGKRHFVKFHFIPHLGVHSLVWDEALKLAGQDPDFHRKDLMEAIDNGAYPKWDFAIQVIPEEKQDDFEFDIFDATKIWPEELVPLRVIGELELNRNVDEFFPQTEQVAFCTSHIVPGIDFSDDPLLQGRNFSYFDTQISRLGINWEEIPINRPVCPVLNHNRDGAKRHRIAQGTVNYWPNRFEAGPPAPVEQGGFASYPAKLNGIKKRGLSPKFREHHNQAQLFYNSLSEHEKVHVKKAFGFELDHCDDPIVYERLAGHRLAEIDLTLAQEVAELVGAPIPDKALRPNHGKRSKHLSQTEFPGKQPTIASRRIAIIIGDGYDPVAFNGLKGAITAVGALPFVIGTKRSPIYADGEDKSSSKGVIADHQYDGQRSTMFDATFIPGGPHVESLKANGQIRYWIIETFGHLKALGATGEAAAFIKEALGSALDVKVATSDNPQPVEWYGVVTAGKIHKPESFKEGIQIVKDAKDFISTFFYQISQHRNYKRELDGLASTVAF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0016209 (antioxidant activity), GO:0003824 (catalytic activity), GO:0004601 (peroxidase activity), GO:0016491 (oxidoreductase activity), GO:0004096 (catalase activity), GO:0016684 (oxidoreductase activity, acting on peroxide as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:1901700 (response to oxygen-containing compound), GO:0010035 (response to inorganic substance), GO:0006979 (response to oxidative stress), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0034599 (cellular response to oxidative stress), GO:0042542 (response to hydrogen peroxide), GO:1901701 (cellular response to oxygen-containing compound), GO:0000302 (response to reactive oxygen species), GO:0062197 (cellular response to chemical stress), GO:0034614 (cellular response to reactive oxygen species), GO:0070301 (cellular response to hydrogen peroxide)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Eukaryotic translation initiation factor 4E, putative (Q387Q8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
InterPro domains:
- IPR023398: Translation Initiation factor eIF- 4e-like (homologous_superfamily) [16-243]
- IPR001040: Translation Initiation factor eIF- 4e (family) [25-233]
Sequence:
MQTLLRPRPGEPTLFGPPTNQCTQLWGVWEMWCVLPDGHEAATATPNVRGSGAKKGGMSKTKVKKATWLDQVRSIGLFDSAEGFWGIITCTLNPSQLPPGFNYYLFRRNIAPMWEHEANRRGGRWVMRFRVSQHDDSPATALDGAVAAAAEGQLPVDRAWEALCVAMIGEQLPGDETEICGAVVRRAERRRDWKLSLWTRTAADRCTQERIGFFVKDLLHLEDGSLQYFSHRELMQASEKGNWDVPPLYQL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0000339 (RNA cap binding), GO:0000340 (RNA 7-methylguanosine cap binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010468 (regulation of gene expression), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Periphilin 1 (F8VWU8)
Organism: Homo sapiens (Human)
Function: Not known
InterPro domains:
- IPR028851: Periphilin-1 (family) [1-168]
Sequence:
MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0010468 (regulation of gene expression), GO:0043484 (regulation of RNA splicing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Variant surface glycoprotein (VSG, atypical), putative (Q380W2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
InterPro domains:
- IPR019609: Trypanosome variant surface glycoprotein, C-terminal (domain) [414-514]
- IPR027446: Variant surface glycoprotein C-terminal domain superfamily (homologous_superfamily) [409-468]
- IPR001812: Trypanosome variant surface glycoprotein, A-type, N-terminal domain (domain) [10-379]
Sequence:
MHTTTAAALILTLTAAMQRHASATAGDVVKGASWTPLCSITADSEKLAANLLQNLIQNARDGETALQRLLRALVYNEATGGQPLSNATMAVWSLYAEVAGRAAARIQQTEAKAVVTAARNIGRLQGAISEFLESQADASADNKGCLQAAAGTTAVIVGKQQLYREQPTCKMSWDEVKNEKTTTSVITATGIKHTNSGGQENGQTIHSGQGTDCDISQPQSSFKLTYGSRGNDVAGHVPKLAAGYFTVDATGFKIPKHDTLQDATTASPYLGKAIEAVTAVPAKEAATSIKTIAELKAHQDFKGPARRYLLGKKLTETDGDTQLEEKITNAYVNDDNAKKALFEAVDAYQIHDNLRPSPADDTLGKITSIHILMHLYFHYRSAREQAIQNRMQKLQEKAKHASDTISTEEKEKECNTKGKDDEEACKKLAKDGCVFNPKGNEGKKCELKKEVKAEPEKEKENEEKDKKTDSKCTGKEQKDCEKAPECKLENNACKNSIFLVNKKPVLMADAFADL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response), GO:0042783 (evasion of host immune response), GO:0020033 (antigenic variation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Csh1p (Q59QH2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
InterPro domains:
- IPR036812: NAD(P)-dependent oxidoreductase domain superfamily (homologous_superfamily) [2-330]
- IPR050523: Aldo/Keto Reductase Detoxification and Biosynthesis (family) [3-330]
- IPR023210: NADP-dependent oxidoreductase domain (domain) [15-325]
Sequence:
MVTRLGKSGLKVNTVAVGTMRLGSSWRGFNGDIDECLKILKFCYDNGFRTFDTADTYSNGKSEELLGLFIKKYNIPRERIVILTKCYFSVKDDAEDSSLEIDPIDYMNGKGLSRKHILAAAEASVKRLGTYIDVLQIHRLDHEVTYEEVMRSLNDVVEQGLARYIGASSMKTWEFVELQNVAKANGWHQFISMQSHYSLLYREDERELNDYCKKNSIGLIPWSPNGGGVLCRPFDSEKTKQFLDNKQWSSLFGLENVRDADKIIVDRVKELSVKYNASMMQVSLAWCISKGVIPIAGVSKFEQAEELVGIFKVNLTEDDIKYLEEPYHAKDLARVAA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051703 (biological process involved in intraspecies interaction between organisms), GO:0009987 (cellular process), GO:0044010 (single-species biofilm formation), GO:0098743 (cell aggregation), GO:0098630 (aggregation of unicellular organisms), GO:0090609 (single-species submerged biofilm formation), GO:0042710 (biofilm formation), GO:0044011 (single-species biofilm formation on inanimate substrate), GO:0090605 (submerged biofilm formation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005618 (cell wall), GO:0009277 (fungal-type cell wall)
Protein: Mitochondrial import inner membrane translocase subunit Tim8 B (Deafness dystonia protein 2 homolog) (P62077)
Organism: Mus musculus (Mouse)
Function: Probable mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Intermembrane side {ECO:0000250}.
InterPro domains:
- IPR035427: Tim10-like domain superfamily (homologous_superfamily) [1-83]
- IPR004217: Tim10-like (domain) [16-76]
Sequence:
MAELGEADEAELQRLVAAEQQKAQFTAQVHHFMELCWDKCVEKPGSRLDSRTENCLSSCVDRFIDTTLAITGRFAQIVQKGGQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0007005 (mitochondrion organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)