lokahq/bioreason-rl huggingface dataset:
Protein: Ribulose bisphosphate carboxylase large chain (RuBisCO large subunit) (EC 4.1.1.39) (Q6ENG6)
Organism: Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea)
Function: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site.
Subcellular location: Plastid, chloroplast.
InterPro domains:
- IPR017443: Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal (domain) [24-144]
- IPR000685: Ribulose bisphosphate carboxylase, large subunit, C-terminal (domain) [154-462]
- IPR033966: RuBisCO (family) [1-474]
- IPR036422: RuBisCO large subunit, N-terminal domain superfamily (homologous_superfamily) [9-149]
- IPR020888: Ribulose bisphosphate carboxylase large subunit, type I (family) [9-475]
- IPR036376: Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily (homologous_superfamily) [148-477]
- IPR020878: Ribulose bisphosphate carboxylase, large chain, active site (active_site) [196-204]
Sequence:
MSPQTETKASVGFKAGVKDYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVVGEDNQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPTYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKSQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGEREMTLGFVDLLRDDFIEKDRARGIFFTQDWVSMPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAAANRVALEACVQARNEGRDLAREGNEIIRSACKWSPELAAACEIWKAIKFEFEPVDKLDS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0005515 (protein binding), GO:0016829 (lyase activity), GO:0016830 (carbon-carbon lyase activity), GO:0046983 (protein dimerization activity), GO:0042803 (protein homodimerization activity), GO:0016831 (carboxy-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009620 (response to fungus), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0050832 (defense response to fungus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0043231 (intracellular membrane-bounded organelle)
Protein: E3 ubiquitin-protein ligase Os06g0535400 (EC 2.3.2.27) (RING-H2 finger protein Os06g0535400) (RING-type E3 ubiquitin transferase Os06g0535400) (Q5Z5F2)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Possesses E3 ubiquitin-protein ligase in vitro.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
InterPro domains:
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [152-232]
- IPR001841: Zinc finger, RING-type (domain) [183-227]
Sequence:
MELPWLDLPFTLLTLLLATRLAYDYYGVVAATFTGSFSLQIFLFYCFARWYRHTIAARAAADADGDGGGGAVADEEAAPPVLIPLLEGRGGGGGGAGAASSLANRCFAVVFMVFVPLVIVVFERSQADVVAYALCLANILVMVVWLSPDAAADPASAAKSFLRLSDDEDEGSCSGSGHGAAEDKCCVCLAGMREAQALRDLPRCGHRFHAKCIGKWLTAHPTCPVCRTTAVPPPAPLPASGDHADDAITPV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0090698 (post-embryonic plant morphogenesis), GO:0099402 (plant organ development), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:1905392 (plant organ morphogenesis), GO:0043170 (macromolecule metabolic process), GO:0048731 (system development), GO:0090696 (post-embryonic plant organ development), GO:0010311 (lateral root formation), GO:0036211 (protein modification process), GO:0048364 (root development), GO:0043412 (macromolecule modification), GO:0010015 (root morphogenesis), GO:0090697 (post-embryonic plant organ morphogenesis), GO:0022622 (root system development), GO:0070647 (protein modification by small protein conjugation or removal), GO:0032446 (protein modification by small protein conjugation), GO:0016567 (protein ubiquitination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Derlin (B4E1G1)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU363059}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU363059}.
InterPro domains:
- IPR007599: Derlin (family) [46-104]
Sequence:
MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLMFRYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGDQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0006984 (ER-nucleus signaling pathway), GO:0006991 (response to sterol depletion), GO:0033554 (cellular response to stress), GO:0032933 (SREBP signaling pathway), GO:0071501 (cellular response to sterol depletion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: MPP4 protein (A2RU80)
Organism: Homo sapiens (Human)
Function: Not known
InterPro domains:
- IPR036034: PDZ superfamily (homologous_superfamily) [130-236]
- IPR008144: Guanylate kinase-like domain (domain) [420-609]
- IPR036892: L27 domain superfamily (homologous_superfamily) [86-136]
- IPR036028: SH3-like domain superfamily (homologous_superfamily) [219-338]
- IPR035600: MPP4, SH3 domain (domain) [246-306]
- IPR001452: SH3 domain (domain) [242-312]
- IPR020590: Guanylate kinase, conserved site (conserved_site) [455-472]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [407-624]
- IPR014775: L27 domain, C-terminal (domain) [90-138]
- IPR050716: Membrane-associated guanylate kinase (family) [20-623]
- IPR008145: Guanylate kinase/L-type calcium channel beta subunit (domain) [419-612]
- IPR001478: PDZ domain (domain) [154-235]
- IPR004172: L27 domain (domain) [24-140]
Sequence:
MIQSDKGADPPDKKDMKLSTATNPQNGLSQILRLVLQELSLFYSRDVNGVCLLYDLLHSPWLQALLKIYDCLQEFKEKKLVPATPHAQVLSYEVVELLRETPTSPEIQELRQMLQAPHFKALLSAHDTIAQKDFEPLLPPLPDNIPESEEAMRIVCLVKNQQPLGATIKRHEMTGDILVARIIHGGLAERSGLLYAGDKLVEVNGVSVEGLDPEQVIHILAMSRGTIMFKVVPVSDPPVNSQQMVYVRAMTEYWPQEDPDIPCMDAGLPFQKGDILQIVDQNDALWWQARKISDPATCAGLVPSNHLLKRKQREFWWSQPYQPHTCLKSTLSISMEEEDDMKIDEKCVEAEELSEDKEEFVGYGQKFFIAGFRRSMRLCRRKSHLSPLHASVCCTGSCYSAVGAPYEEVVRYQRRPSDKYRLIVLMGPSGVGVNELRRQLIEFNPSHFQSAVPHTTRTKKSYEMNGREYHYVSKETFENLIYSHRMLEYGEYKGHLYGTSVDAVQTVLVEGKICVMDLEPQDIQGVRTHELKPYVIFIKPSNMRCMKQSRKNAKIITDYYVDMKFKDEDLQEMENLAQRMETQFGQFFDHVIVNDSLHDACAQLLSAIQKAQEEPQWVPATWISSDTESQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0046907 (intracellular transport), GO:0051668 (localization within membrane), GO:0045184 (establishment of protein localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0006886 (intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0008104 (protein localization), GO:0015031 (protein transport), GO:0090150 (establishment of protein localization to membrane), GO:0072657 (protein localization to membrane), GO:0006612 (protein targeting to membrane), GO:0006605 (protein targeting)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0030054 (cell junction), GO:0043229 (intracellular organelle), GO:0070161 (anchoring junction), GO:0043228 (non-membrane-bounded organelle), GO:0005911 (cell-cell junction), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0005912 (adherens junction), GO:0015629 (actin cytoskeleton)
Protein: Epsin (Q54EH1)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2).
Subcellular location: Membrane, clathrin-coated pit {ECO:0000269|PubMed:18827012}.
InterPro domains:
- IPR013809: ENTH domain (domain) [14-145]
- IPR008942: ENTH/VHS (homologous_superfamily) [13-159]
Sequence:
METMIKSYIKKGKDAVLNTPEIERKVRDATSNDKWGPSGTQMQEISRASYNYECFPIIMGVIWKRINDPGKFWRHVYKSLLLIDYLVRNGSPQVIRDCRHHTMEIKTLVEFQYIEEEKDVGLSVRERAKQVIDLLQDDQRIKEERDKAKTNQNKYVGIGNDSRDFGYGGGSYGGGGYDSDSYGSNQRDSYGGNQRDSYGGNQRDSYGGNQRETTRRDSFNGRDEGYGNNNNNNNNNSYDSDPYSNTRAEYENYSNRAETRRNNEFGDDSNNSYNNNNNFNNNNNNNNSYNNSNNSNNSNNNNNNNNYNNSNNNSNNIQNNPNAASGGRSRPRAASGSGPSPATPNFQSSQQQQQPTLIDFSEPTPANKPMVFDPLADLASGMNNTNNNNNNNNNNSNSFGGFQSVNNNQNSFNFNNNNQQQQQQNNFLQLTQSNPQQSNNNNNNNNFFNQQPQQAQQFGQFQNSSMNKDPFAKDEFGDFAGANGNADFNPFDQQSGDFSNKNDGQQKPKDTNDPWSKKDLFDLSNLGNQNPNQSPVNNTNNNNNGNTRSQPARVANGPITSAGSTIPTMRPQPMMNQGFNGGMMNQGMGGFNQGGGMNNMNGMNQGGMNNMNGMNQGGMNQGGMGGFNQGGMNNMGGMNQGGMNNMGGMNNMGGMNSMNGMNQGGMGFNQSGANRNTNSMGSAGRF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0008289 (lipid binding), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0030276 (clathrin binding), GO:0005543 (phospholipid binding), GO:0043168 (anion binding), GO:0035091 (phosphatidylinositol binding), GO:0080025 (phosphatidylinositol-3,5-bisphosphate binding), GO:1901981 (phosphatidylinositol phosphate binding), GO:0032266 (phosphatidylinositol-3-phosphate binding), GO:1902936 (phosphatidylinositol bisphosphate binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006810 (transport), GO:0016192 (vesicle-mediated transport), GO:0006996 (organelle organization), GO:0061024 (membrane organization), GO:0006900 (vesicle budding from membrane), GO:0016050 (vesicle organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0030139 (endocytic vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle), GO:0045335 (phagocytic vesicle)
Protein: Sorting nexin 1 (H0YKD5)
Organism: Homo sapiens (Human)
Function: Not known
InterPro domains:
- IPR005329: Sorting nexin, N-terminal (domain) [10-90]
Sequence:
MASGGGGCSASERLPPPFPGLEPESEGAAGGSEPEAGDSDTEGEDIFTGAAVVSKHQSPKITTSLLPINNGSKENGIHEEQDQEPQDLFADKLTIVQKQTVCSKKKI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0009894 (regulation of catabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0031329 (regulation of cellular catabolic process), GO:0010506 (regulation of autophagy)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005773 (vacuole), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0005764 (lysosome), GO:0097708 (intracellular vesicle)
Protein: High-energy light unresponsive protein 1 (Q17990)
Organism: Caenorhabditis elegans
Function: Photoreceptor for short wavelength (UV) light that mediates UV-light-induced avoidance behavior. Directly senses and absorbs both UV-A and UV-B light with very high efficiency. Absorption of UV-B but not UV-A light shows resistance to photobleaching. In contrast to other photoreceptors, does not use a prosthetic chromophore to capture photons and only depends on its protein conformation. Might have a role in response to white light exposure.
Subcellular location: Cell membrane {ECO:0000269|PubMed:27863243}; Multi-pass membrane protein {ECO:0000255}.
InterPro domains:
- IPR013604: 7TM chemosensory receptor (family) [48-425]
Sequence:
MPPPSSHSNIFHSTFKHTVKETMANAKKTMIAKILSSRNKWAICDRTLYPIYYLLLILGLNQSIRPNNSLLFRIYSWLVFCLLLFTTLRKFNQVGVRPNGTRENLQEFFANPRSMITLCNALIMLSGLLASLQLYTLGAKRLKPLKILCQFSLNVRTKQAERRQFMINTFLAVFSGLLALTMAATYAMSKWGYILYIVGTPNLDTETIFCVLLDSYALFVSRAAISALAILFYQHCSVIRRSIKHLINEMVPAEQDECPLPESSLQKIHDCQISYQRIFNGKAVIEEYYSFVLFYSYGVCIPIFCFLMFVGMSAQSICWSEVVSIVIWIVNAILVLLLFSLPAFMINEDGDRLVASSFRMYHETFHEERDLTVLSQMTFFTFQIHSTKLTLSACNYFYMDRSILLSLFSAILTYFLILWEFDIKNNQSLQNIANHTIHT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0008527 (taste receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0007610 (behavior), GO:0007631 (feeding behavior), GO:0042755 (eating behavior), GO:0043050 (pharyngeal pumping)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0031252 (cell leading edge), GO:0031256 (leading edge membrane), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0036477 (somatodendritic compartment), GO:0071944 (cell periphery), GO:0098590 (plasma membrane region), GO:0120025 (plasma membrane bounded cell projection), GO:0097447 (dendritic tree), GO:0032589 (neuron projection membrane), GO:0005886 (plasma membrane), GO:0043005 (neuron projection), GO:0032590 (dendrite membrane), GO:0031253 (cell projection membrane), GO:0030425 (dendrite)
Protein: D-lactate dehydrogenase (cytochrome) (EC 1.1.2.4) (A0A0G2K1W9)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
InterPro domains:
- IPR016167: FAD-binding, type PCMH, subdomain 1 (homologous_superfamily) [6-119]
- IPR006094: FAD linked oxidase, N-terminal (domain) [66-202]
- IPR016166: FAD-binding domain, PCMH-type (domain) [62-242]
- IPR016169: FAD-binding, type PCMH, subdomain 2 (homologous_superfamily) [121-243]
- IPR004113: FAD-binding oxidoreductase/transferase, type 4, C-terminal (domain) [243-483]
- IPR016171: Vanillyl-alcohol oxidase, C-terminal subdomain 2 (homologous_superfamily) [444-484]
- IPR036318: FAD-binding, type PCMH-like superfamily (homologous_superfamily) [28-243]
- IPR016164: FAD-linked oxidase-like, C-terminal (homologous_superfamily) [246-484]
Sequence:
RAMLLRVATQRLSPWRGYCSRGSQGGLSQDFVEALKAVVGSPHVSTASAVRQHHGHDESMHRCRPPDAVVWPQNVDQVSRLASLCYNQGVPIIPFGTGTGVEGGVCAVQGGVCISLTHMDQIMELNTEDFSVVVEPGVTRKALNTHLRNSGLWFPVDPGADASLCGMAATGASGTNAVRYGTMRDNVINLEVVLPDGRLLHTAGRGRHYRKSAAGYNLTGLFVGSEGTLGIITSATLRLHPAPEATVAATCAFPSVQAAVDSTVQILQAAVPVARIEFLDEVMMDACNRHSKLNCPVAPTLFLEFHGSQQALAEQLQRTEAITQDNGGSHFSWAKEAEKRNELWAARHNAWYAALALRPGSKAYSTDVCVPISRLPEILVETKEELKASKLTGVIVGHVGDGNFHCILLVNPDDVEEQRRVKAFAENLGRRALALHGTCTGEHGIGLGKRQLLQEEVGPVGVETMRQLKDTLDPRGLMNPGKVL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0009056 (catabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:0044282 (small molecule catabolic process), GO:1901575 (organic substance catabolic process), GO:0006082 (organic acid metabolic process), GO:0044248 (cellular catabolic process), GO:0006089 (lactate metabolic process), GO:0016054 (organic acid catabolic process), GO:1901616 (organic hydroxy compound catabolic process), GO:0043436 (oxoacid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0046395 (carboxylic acid catabolic process), GO:0072329 (monocarboxylic acid catabolic process), GO:0032787 (monocarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005740 (mitochondrial envelope), GO:0019866 (organelle inner membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031966 (mitochondrial membrane), GO:0005743 (mitochondrial inner membrane)
Protein: Homeobox protein Hox-B3 (Homeobox protein Hox-2.7) (Homeobox protein Hox-2G) (P14651)
Organism: Homo sapiens (Human)
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular location: Nucleus.
InterPro domains:
- IPR001356: Homeodomain (domain) [186-250]
- IPR020479: Homeodomain, metazoa (domain) [210-244]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [175-248]
- IPR017970: Homeobox, conserved site (conserved_site) [221-244]
- IPR001827: Homeobox protein, antennapedia type, conserved site (conserved_site) [129-134]
- IPR025281: Domain of unknown function DUF4074 (domain) [366-429]
Sequence:
MQKATYYDNAAAALFGGYSSYPGSNGFGFDVPPQPPFQAATHLEGDYQRSACSLQSLGNAAPHAKSKELNGSCMRPGLAPEPLSAPPGSPPPSAAPTSATSNSSNGGGPSKSGPPKCGPGTNSTLTKQIFPWMKESRQTSKLKNNSPGTAEGCGGGGGGGGGGGSGGSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAGSPPQPMQSTAGFMNALHSMTPSYESPSPPAFGKAHQNAYALPSNYQPPLKGCGAPQKYPPTPAPEYEPHVLQANGGAYGTPTMQGSPVYVGGGGYADPLPPPAGPSLYGLNHLSHHPSGNLDYNGAPPMAPSQHHGPCEPHPTYTDLSSHHAPPPQGRIQEAPKLTHL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048731 (system development), GO:0001501 (skeletal system development), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)