lokahq/bioreason-rl huggingface dataset:
Protein: Ada2a-containing complex component 1 (LD21610p) (Q9VM59)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
InterPro domains:
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [127-188]
- IPR037830: ZZ-type zinc finger-containing protein 3 (family) [9-350]
- IPR001005: SANT/Myb domain (domain) [131-185]
Sequence:
MEIAEISAEDEDVFHFETEHLALRGNQCYTNLLRTLAVLQAQRIRVHQQIEELEATQNIYLENPQHMLDKLRNNEPLIADNYITTTVLPDLPTLSPNDEEGGTNETPTDASSWTQEANKNRDRSNGRSENFNRLWTNEEQSRLEQLLIQYPPEEVEMRRFGKIAKALGNRTAQQVYSRVQKYFQKLHDAGMPVPGRIPKHRRPGLSKPKIKLRKSTFFPAHNISLQMPEDDFTFDDLRIPSPASDMLLMPASKIEPKIESEYMDADLNAESKRKQELCLKLLSAIQDEKREMEDGYEPDLLAAKCAECEEASVTRTQWRCNSCYCYLNLCGDCLASQLIEGRFEHLSHEVVVDQES
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0006357 (regulation of transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000785 (chromatin), GO:1902494 (catalytic complex), GO:0140535 (intracellular protein-containing complex), GO:0031248 (protein acetyltransferase complex), GO:1990234 (transferase complex), GO:0043229 (intracellular organelle), GO:0000123 (histone acetyltransferase complex), GO:0043228 (non-membrane-bounded organelle), GO:0070461 (SAGA-type complex), GO:1902493 (acetyltransferase complex), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0140672 (ATAC complex), GO:0005694 (chromosome)
Protein: Histone deacetylase 11 (HD11) (EC 3.5.1.98) (Q96DB2)
Organism: Homo sapiens (Human)
Function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
Subcellular location: Nucleus {ECO:0000269|PubMed:11948178}.
InterPro domains:
- IPR037138: Histone deacetylase domain superfamily (homologous_superfamily) [16-337]
- IPR000286: Histone deacetylase HDAC (family) [139-261]
- IPR044150: Histone deacetylase 11 (domain) [35-319]
- IPR023696: Ureohydrolase domain superfamily (homologous_superfamily) [13-320]
- IPR023801: Histone deacetylase domain (domain) [35-316]
Sequence:
MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVERNIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVTSGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006325 (chromatin organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:1902494 (catalytic complex), GO:0140513 (nuclear protein-containing complex), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0000118 (histone deacetylase complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Homeodomain-like superfamily protein (Q9XEB2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
InterPro domains:
- IPR001005: SANT/Myb domain (domain) [16-67]
- IPR046955: Myb family transcription factor PHR1-like (family) [5-116]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [13-72]
- IPR017930: Myb domain (domain) [11-71]
- IPR006447: Myb domain, plants (domain) [14-70]
Sequence:
MQDPMVRSYIRSDNPRMHWTDDLDIRFIQVIEKLGGEESATPKRILSLMGVRDLTISHVKSHLQMYRNKKKEESSKEIKMMREMTQRQSQQYLQIYERATQFIQNQQRLQLDNTEKITPVLGSSNKSLDQSSKVGLNENRGNDVVVVGGATGEEELSLELTLGRKY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: NAC (No Apical Meristem) domain transcriptional regulator superfamily protein (T27C4.5 protein) (Q9M846)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
InterPro domains:
- IPR003441: NAC domain (domain) [3-76]
- IPR036093: NAC domain superfamily (homologous_superfamily) [3-57]
Sequence:
MVNPVGFRFRPTKEEIVDHYLRPTNFDGDTSHVDRNIMFMQDNRNDYRPPNSLTGVFSDCSSDDNDSDLLSPKTVS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Lysozyme 3 (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase 3) (Invertebrate-type lysozyme 3) (cv-lysozyme 3) (B3A003)
Organism: Crassostrea virginica (Eastern oyster)
Function: Has antibacterial activity against the Gram-negative bacterium E.coli. No antibacterial activity detected against the Gram-negative bacterium V.vulnificus.
Subcellular location: Secreted {ECO:0000250|UniProtKB:P83673}.
InterPro domains:
- IPR023346: Lysozyme-like domain superfamily (homologous_superfamily) [71-160]
- IPR008597: Invertebrate-type lysozyme (family) [51-183]
Sequence:
MNGLFLFCVATTAALAYGSDAPCTNSGGVCQDDHLACHNGHYQSGLCTGGAHRRCCLTSASHTGSFSTGIVSQQCLQCICNVESGCKAIGCHFDVNSDSCGYFQIKEGYWHDCGSPGSSWRSCANDLACASKCVQAYMSRYIGFSGCSHSCESYARIHNGGPAGCKHTNTLGYWSHVHAQGCSHNSK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0061783 (peptidoglycan muralytic activity), GO:0016787 (hydrolase activity), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0003796 (lysozyme activity), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0006950 (response to stress), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006952 (defense response), GO:0043207 (response to external biotic stimulus), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0042742 (defense response to bacterium), GO:0050829 (defense response to Gram-negative bacterium), GO:0050830 (defense response to Gram-positive bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Uncharacterized protein (Q585M8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
InterPro domains:
- IPR001680: WD40 repeat (repeat) [140-417]
- IPR019775: WD40 repeat, conserved site (conserved_site) [301-315]
- IPR020472: PAC1/LIS1-like, WD-40 repeat (repeat) [208-315]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [106-439]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [110-411]
- IPR045245: Pre-mRNA 3' end processing protein Pfs2-like (family) [9-426]
Sequence:
MEFETERSTTRTQQQPRQKFRGQEYDDYVPRRKTHGQRSVDFYSSAIQYVTTRLQHRNTPYGYHVDPHPYCSKDMLPAFRTPFNPSTALCTQWVSTSYHPDSRGGLSRQGLLNLKWAPNGRRLLCSTGRGEFLLFNGHSFGVEVKTVAHEDHRPCRAITWGNNSDLIISGDDAGMVKLWLSNFVLVAEFNSHHRAVRELTWAPLEGKFCSCGQDGSARVWDTNAVGTNPQQAREEMKLEGHGGDVVSVDWHPYHSLILTGSQDRDCRLWDPRTASRGSIAALQGHAQSVNCVRWNPSGTMLLSASKDCTLKLWDIRMVQEVASYEAHSKSVERVEWHPHVPDLFVSAGADGSIMYWMVDGCEGTARQDGVLVVIHNAALVESAHDRFRDVANPINAIAWSPLGNLLASCSSEVKYWHRNIPGAMEEKERGEEDDVFEMNRQQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0044248 (cellular catabolic process), GO:0009057 (macromolecule catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0006508 (proteolysis), GO:0044265 (cellular macromolecule catabolic process), GO:0030163 (protein catabolic process), GO:0043632 (modification-dependent macromolecule catabolic process), GO:0051603 (proteolysis involved in protein catabolic process), GO:0019941 (modification-dependent protein catabolic process), GO:0006511 (ubiquitin-dependent protein catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase) (LAL) (EC 3.1.1.13) (Cholesteryl esterase) (Diacylglycerol lipase) (Lipase A) (Sterol esterase) (Triacylglycerol ester hydrolase) (Triacylglycerol lipase) (Q64194)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol.
Subcellular location: Lysosome {ECO:0000269|PubMed:4062953}.
InterPro domains:
- IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [22-395]
- IPR025483: Lipase, eukaryotic (family) [1-397]
- IPR000073: Alpha/beta hydrolase fold-1 (domain) [84-378]
Sequence:
MQLLGRVICFVVGILLSGGPTGTISAVDPEANMNVTEIIMHWGYPEHSVQTGDGYILGVHRIPHGRKNQFDKGPKPVVYLQWRHGFLADSSNWVTNIDNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEYWAFSFDEMAKYDLPASINYILNKTGQEQLYNVGHSQGCTIGFIAFSQMPELAKKVKMFFALAPVLSLNFASGPMVKLGRLPDLLLEDLFGQKQFLPQSAMVKWLSTHICTHVIMKELCANIFFLICGFNEKNLNMSRVDVYTTHCPAGTSVQNMVHWTQVVKYHKLQAFDWGSSDKNYFHYNQSYPPLYSIKDMQLPTALWSGGKDWLADTSDINILLTEIPTLVYHKNIPEWDHLDFIWGLDAPWRLYNEVVSLMKKYQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016491 (oxidoreductase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016298 (lipase activity), GO:0052689 (carboxylic ester hydrolase activity), GO:0016615 (malate dehydrogenase activity), GO:0004806 (triglyceride lipase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0044281 (small molecule metabolic process), GO:0007586 (digestion), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006082 (organic acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0043648 (dicarboxylic acid metabolic process), GO:0006108 (malate metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Retinol dehydrogenase 14 (All-trans and 9-cis), isoform CRA_a (cDNA, FLJ95921, Homo sapiens retinol dehydrogenase 14 (all-trans and 9-cis)(RDH14), mRNA) (Q53RX3)
Organism: Homo sapiens (Human)
Function: Not known
InterPro domains:
- IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [41-308]
- IPR002347: Short-chain dehydrogenase/reductase SDR (family) [44-292]
Sequence:
MAVATAAAVLAALGGALWLAARRFVGPRVQRLRRGGDPGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPVEGAQTSIYLASSPEVEGVSGRYFGDCKEEELLPKAMDESVARKLWDISEVMVGLLK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor), GO:0004033 (aldo-keto reductase (NADP) activity), GO:0008106 (alcohol dehydrogenase (NADP+) activity), GO:0052650 (NADP-retinol dehydrogenase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0001503 (ossification), GO:0030154 (cell differentiation), GO:0001649 (osteoblast differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005829 (cytosol), GO:0005654 (nucleoplasm), GO:0031984 (organelle subcompartment), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0043229 (intracellular organelle), GO:0098827 (endoplasmic reticulum subcompartment), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0005773 (vacuole), GO:0043233 (organelle lumen), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0005789 (endoplasmic reticulum membrane), GO:0005774 (vacuolar membrane), GO:0070013 (intracellular organelle lumen), GO:0005764 (lysosome), GO:0005634 (nucleus), GO:0031981 (nuclear lumen), GO:0098852 (lytic vacuole membrane), GO:0005765 (lysosomal membrane)
Protein: Phospholipase A2-beta (F4ITF6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
InterPro domains:
- IPR033113: Phospholipase A2, histidine active site (active_site) [70-77]
- IPR036444: Phospholipase A2 domain superfamily (homologous_superfamily) [19-146]
Sequence:
MMFRTSLMRFAAAFFAIVFVVLVGVARSEECTRTCIAQNCDTLSIRYGKYCGIGHSGCPGEEPCDDLDACCKIHDHCVELNGMTNISCHKKFQRCVNRLSKAIKQSKNKKVGFSTKCPYSVVIPTVNQGMDIGILFSQLAYHRKFVTD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0016298 (lipase activity), GO:0052689 (carboxylic ester hydrolase activity), GO:0004623 (phospholipase A2 activity), GO:0004620 (phospholipase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0048589 (developmental growth), GO:0009856 (pollination), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0009628 (response to abiotic stimulus), GO:0044706 (multi-multicellular organism process), GO:0009653 (anatomical structure morphogenesis), GO:0016049 (cell growth), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0009846 (pollen germination), GO:0045927 (positive regulation of growth), GO:0003006 (developmental process involved in reproduction), GO:0040008 (regulation of growth), GO:0048522 (positive regulation of cellular process), GO:0000902 (cell morphogenesis), GO:0048588 (developmental cell growth), GO:0048468 (cell development), GO:0060560 (developmental growth involved in morphogenesis), GO:0030154 (cell differentiation), GO:0009826 (unidimensional cell growth), GO:0001558 (regulation of cell growth), GO:0009629 (response to gravity), GO:0009860 (pollen tube growth), GO:0048868 (pollen tube development), GO:0030307 (positive regulation of cell growth), GO:0051128 (regulation of cellular component organization), GO:0010033 (response to organic substance), GO:0009606 (tropism), GO:0009725 (response to hormone), GO:0009630 (gravitropism), GO:0000904 (cell morphogenesis involved in differentiation), GO:0009733 (response to auxin), GO:0009932 (cell tip growth)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Allantoicase (EC 3.5.3.4) (Allantoate amidinohydrolase) (P25335)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Utilization of purines as secondary nitrogen sources, when primary sources are limiting.
InterPro domains:
- IPR005164: Allantoicase (family) [1-343]
- IPR015908: Allantoicase domain (domain) [31-342]
- IPR008979: Galactose-binding-like domain superfamily (homologous_superfamily) [4-343]
Sequence:
MKFFSLADEAEFKSIIISKNKAVDVIGSKLGGQVVSFSDEWFASAENLIQPTAPIRDPTRFVHSGAWYDGWETRRHNEMEYDWVIIKMGVAAAHIIGGEIDTAFFNGNHAPFVSIEALYDEGEEGNIVEDDSRWVEIVEKFECGPSQRHLFVRGNGLTKERFTHIKLKMYPDGGIARFRLYGRVVPPELKTKDHIIDLAYVCNGAVALKYSDQHFGSVDNLLLPGRGHDMSDGWETKRSRQPGHTDWAVIQLGRESSFIEKIIVDTAHFRGNFPQFITVEGCLKESESSENTGEGTWVELVGKSKTGPDKEHVYEIRKSIRVSHVKLTIIPDGGVKRIRVWGY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0016813 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0071941 (nitrogen cycle metabolic process), GO:0019627 (urea metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0000050 (urea cycle), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)