lokahq/bioreason-rl huggingface dataset:
Protein: RHOMBOID-like protein 10, chloroplastic (AtRBL10) (EC 3.4.21.-) (F4ICF4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Required for correct root growth, floral development, fertility and photoprotection. May be involved in TIC22 processing during its import and in AOS accumulation in the chloroplast membrane.
Subcellular location: Plastid, chloroplast membrane {ECO:0000269|PubMed:22416142, ECO:0000269|PubMed:22738221}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes probably to the inner membrane. {ECO:0000303|PubMed:22738221}.
InterPro domains:
- IPR035952: Rhomboid-like superfamily (homologous_superfamily) [123-312]
- IPR022764: Peptidase S54, rhomboid domain (domain) [164-309]
- IPR050925: Rhomboid protease S54 (family) [21-311]
Sequence:
MVSVSLSHHNLWPPESGSTAFRGFATAASVHACHHVSRHLRLDFHLRSSLKKLQHFSDDARMKFARYQRVFVFNGANFLKSRVDIRLSQSSPFVCFFNGGESRLNPRGGEEGSSNPETSKRNTVNGRRWTNVLLAINVIMYIAQIASDGKVLTWGAKINSLIERGQLWRLATASVLHANPMHLMINCYSLNSIGPTAESLGGPKRFLAVYLTSAVAKPILRVLGSAMSYWFNKAPSVGASGAIFGLVGSVAVFVIRHKQMVRGGNEDLMQIAQIIALNMAMGLMSRRIDNWGHIGGLLGGTAMTWLLGPQWKYEYTTRDGRRVFMDSAPIPLLLRWRNEQRRL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0008233 (peptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0016043 (cellular component organization), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0051604 (protein maturation), GO:0006508 (proteolysis), GO:0006996 (organelle organization), GO:0010467 (gene expression), GO:0061024 (membrane organization), GO:0009668 (plastid membrane organization), GO:0009657 (plastid organization), GO:0010027 (thylakoid membrane organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009526 (plastid envelope), GO:0042170 (plastid membrane), GO:0009507 (chloroplast), GO:0019866 (organelle inner membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031969 (chloroplast membrane), GO:0009941 (chloroplast envelope), GO:0009528 (plastid inner membrane), GO:0009706 (chloroplast inner membrane)
Protein: DNA replication complex GINS protein SLD5 (GINS complex subunit 4) [Cleaved into: DNA replication complex GINS protein SLD5, N-terminally processed] (Q99LZ3)
Organism: Mus musculus (Mouse)
Function: Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.
Subcellular location: Nucleus {ECO:0000269|PubMed:16338220}. Chromosome {ECO:0000250|UniProtKB:Q7ZT48}. Cytoplasm {ECO:0000269|PubMed:16338220}.
InterPro domains:
- IPR038749: GINS complex protein Sld5, alpha-helical domain (domain) [26-146]
- IPR008591: GINS complex subunit Sld5 (family) [1-223]
- IPR021151: GINS subunit, domain A (domain) [72-144]
- IPR031633: DNA replication complex GINS protein SLD5, C-terminal (domain) [165-223]
- IPR036224: GINS, helical bundle-like domain superfamily (homologous_superfamily) [21-163]
Sequence:
MTEVLDLHGQDSDGGSEEMVLTPAELIEKLEQAWMNEKFAPELLESKAEIVECVMEQLEHMEENLRRAKKGDLKVSIHRMEMERIRYVLSSYLRCRLMKIEKFFPHILEKEKVRSEGEPSSLSPEEFVFAKEYMDHTETHFKNVALKHMPPNLQKVDLLRAVPKPDLDSYVFLRVKERQENILVEPEADEQRDYVIDLEVGSQHLIRYKTIAPLVASGAVQLI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0040007 (growth), GO:0032501 (multicellular organismal process), GO:0048589 (developmental growth), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0008283 (cell population proliferation), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0001824 (blastocyst development), GO:0009790 (embryo development), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0001832 (blastocyst growth), GO:0046483 (heterocycle metabolic process), GO:0006259 (DNA metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development), GO:0006260 (DNA replication), GO:0001701 (in utero embryonic development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Capsid protein (Core antigen) (Core protein) (HBcAg) (p21.5) (B1Q2W9)
Organism: Hepatitis B virus subtype adr (HBV)
Function: Not known
Subcellular location: Secreted {ECO:0000256|RuleBase:RU361253}. Virion {ECO:0000256|HAMAP-Rule:MF_04076}. Host cytoplasm {ECO:0000256|HAMAP-Rule:MF_04076}.
InterPro domains:
- IPR002006: Hepatitis core antigen (family) [30-212]
- IPR036459: Viral capsid core domain supefamily, Hepatitis B virus (homologous_superfamily) [20-178]
- IPR013195: Hepatitis B virus, capsid N-terminal (domain) [1-27]
Sequence:
MQLFHLCLIISCSCPTVQASKLCLGWLWGMDIDPYKEFGASVELLSFLPSDFFPSIRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMNLATWVGSNLEDPASRELVVSYVNVNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response), GO:0052553 (modulation by symbiont of host immune response), GO:0042783 (evasion of host immune response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0033643 (host cell part), GO:0043657 (host cell), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0030430 (host cell cytoplasm)
Protein: G-protein coupled receptor family C group 5 member C (Retinoic acid-induced gene 3 protein) (RAIG-3) (Q9NQ84)
Organism: Homo sapiens (Human)
Function: This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
Subcellular location: Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Localized in the plasma membrane and perinuclear vesicles.
InterPro domains:
- IPR051753: Retinoic acid-inducible GPCR family 3 (family) [1-401]
- IPR017978: GPCR family 3, C-terminal (domain) [45-299]
Sequence:
MAIHKALVMCLGLPLFLFPGAWAQGHVPPGCSQGLNPLYYNLCDRSGAWGIVLEAVAGAGIVTTFVLTIILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACVVKPDFSTCASRRFLFGVLFAICFSCLAAHVFALNFLARKNHGPRGWVIFTVALLLTLVEVIINTEWLIITLVRGSGEGGPQGNSSAGWAVASPCAIANMDFVMALIYVMLLLLGAFLGAWPALCGRYKRWRKHGVFVLLTTATSVAIWVVWIVMYTYGNKQHNSPTWDDPTLAIALAANAWAFVLFYVIPEVSQVTKSSPEQSYQGDMYPTRGVGYETILKEQKGQSMFVENKAFSMDEPVAAKRPVSPYSGYNGQLLTSVYQPTEMALMHKVPSEGAYDIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPYVWD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005615 (extracellular space), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0005576 (extracellular region), GO:0043230 (extracellular organelle), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0070062 (extracellular exosome), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031982 (vesicle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:1903561 (extracellular vesicle), GO:0005634 (nucleus)
Protein: Prespore protein Dp87 (Q04503)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Not known
Subcellular location: Spore wall. Note=Stored in prespore vacuoles until it is discharged into the interspace of spores during spore formation.
InterPro domains:
- IPR053121: Spore Coat Assembly Protein (family) [10-554]
- IPR007643: Dictyostelium spore coat protein, N-terminal (domain) [28-140]
- IPR003645: Follistatin-like, N-terminal (domain) [148-384]
Sequence:
MRILYLASLLFLITLYLSPTFGWGGGRDCESHRSEYTCKSDRSCAYLPFVSCCGKKEFFCVNRDHRNCCDDLSCAKNTRTGEIFEIWSSCKPHRDFVPYHSPNTTTCESLGCEARGMECEWVESSPCYGTSCCPRIPRCVGHHGGGHKCDRMRCPEGFYCEEQGGSACCVPHHDGCGNIQCPWGHYCVNEHGKCRCVPHRPPPRPPVDQCRNQHCPHGYSCRVIKGCATCVRDARPPHNLCRGFGCPEGSHCEVLEKHPVCVRNHVPPHPPPPPQICGSVNCGPGYICTIINGHPTCIRGDGYLCNQTRCPHDYQCETISTNIVKCSPKNDECKWHRCPPGSSCFNSRNGPHCLANNVFPQLCKVTQCPTDFSCKMIRGNPTCIKARPPVPPPHCSTCAELSSACNHVGMICIQVPSNCTNTRFPCCPSHPICIHPSTTAASTIATTASTVATTTSATTAGTTTGGTTTGGSTSDSSAASSADSSAASSSPSSSAASSAASSEPSSSAASSSAPSSASSSAPSSASSSAPSSSASSSAASSAASSESSESSSATS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0043934 (sporulation), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0071554 (cell wall organization or biogenesis), GO:0032989 (cellular component morphogenesis), GO:0030435 (sporulation resulting in formation of a cellular spore), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0071555 (cell wall organization), GO:0010927 (cellular component assembly involved in morphogenesis), GO:0042546 (cell wall biogenesis), GO:0070726 (cell wall assembly), GO:0042244 (spore wall assembly), GO:0045229 (external encapsulating structure organization), GO:0070590 (spore wall biogenesis), GO:0022607 (cellular component assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix)
Protein: (thale cress) hypothetical protein (A0A178VTR0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
InterPro domains:
- IPR016181: Acyl-CoA N-acyltransferase (homologous_superfamily) [23-182]
- IPR000182: GNAT domain (domain) [25-183]
Sequence:
MEMDSTTTIKPETLSTVSSSPPEKIHLRPMTLSDVDDFMVWATDSNVTRFCTWEPYTSREAAIAYLNDALLPHPWLRAICLDNDRPIGSISVTPVDEIRGEIGYVLGSKYWGKGIATEAVRLVAGEIFKEKPEMQRLEALVDVDNVGSQKVLEKVGFVKEGVMRKFMYLKGNVRDMVMFSFLPSDSLH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009719 (response to endogenous stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:1901700 (response to oxygen-containing compound), GO:0033993 (response to lipid), GO:0097305 (response to alcohol), GO:0009737 (response to abscisic acid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: C-X-C motif chemokine 3 (GRO-gamma(1-73)) (Growth-regulated protein gamma) (GRO-gamma) (Macrophage inflammatory protein 2-beta) (MIP2-beta) [Cleaved into: GRO-gamma(5-73)] (P19876)
Organism: Homo sapiens (Human)
Function: Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.
Subcellular location: Secreted.
InterPro domains:
- IPR033899: CXC Chemokine domain (domain) [40-102]
- IPR036048: Chemokine interleukin-8-like superfamily (homologous_superfamily) [22-103]
- IPR001089: CXC chemokine (family) [42-97]
- IPR018048: CXC chemokine, conserved site (conserved_site) [43-87]
- IPR001811: Chemokine interleukin-8-like domain (domain) [40-100]
- IPR039809: Chemokine beta/gamma/delta (family) [18-105]
Sequence:
MAHATLSAAPSNPRLLRVALLLLLLVAASRRAAGASVVTELRCQCLQTLQGIHLKNIQSVNVRSPGPHCAQTEVIATLKNGKKACLNPASPMVQKIIEKILNKGSTN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (signaling receptor activator activity), GO:0005126 (cytokine receptor binding), GO:0048018 (receptor ligand activity), GO:0001664 (G protein-coupled receptor binding), GO:0005125 (cytokine activity), GO:0042379 (chemokine receptor binding), GO:0008009 (chemokine activity)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0002376 (immune system process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0042330 (taxis), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:0006955 (immune response), GO:0006952 (defense response), GO:0043207 (response to external biotic stimulus), GO:0006935 (chemotaxis), GO:0010033 (response to organic substance), GO:0009617 (response to bacterium), GO:0006959 (humoral immune response), GO:0098542 (defense response to other organism), GO:0002237 (response to molecule of bacterial origin), GO:0019730 (antimicrobial humoral response), GO:0006954 (inflammatory response), GO:0061844 (antimicrobial humoral immune response mediated by antimicrobial peptide)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (A0A8I6ANK9)
Organism: Rattus norvegicus (Rat)
Function: Not known
InterPro domains:
- IPR002305: Aminoacyl-tRNA synthetase, class Ic (family) [36-265]
- IPR001412: Aminoacyl-tRNA synthetase, class I, conserved site (conserved_site) [43-52]
- IPR050203: Tryptophan--tRNA ligase (family) [118-332]
- IPR014729: Rossmann-like alpha/beta/alpha sandwich fold (homologous_superfamily) [25-192]
- IPR002306: Tryptophan-tRNA ligase (family) [36-285]
Sequence:
MALFSVRKARECWRFIRALHKGPTATAAPQKESGERVFSGIQPTGIPHLGNYLGAIESWVKLQEEYDTVIYSIVDLHSITVPQDPGILQQSILDMTAVLLACGIDPERSILFQQSQAKAARQKHDGTVGLLTYPVLQAADILCYKSTHVPVGEDQVQHMELVQDLARSFNQKYGELFPLPRSILTSMKKVKSLRDPSAKMSKSDPDKLATVQITDSPEEIVRKFRKAVTDFTSEVTYEPDSRPGVSNMVAIHAAVSGLSVEEVVRNSAGVDTARYKLLVADAVIEKFAPIRSEIEKLKMDKDHLRKVLLVGSAKAKELASPVFEEVKKLVGIL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016874 (ligase activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0140098 (catalytic activity, acting on RNA), GO:0016875 (ligase activity, forming carbon-oxygen bonds), GO:0004812 (aminoacyl-tRNA ligase activity), GO:0140101 (catalytic activity, acting on a tRNA)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0051094 (positive regulation of developmental process), GO:0050793 (regulation of developmental process), GO:0051240 (positive regulation of multicellular organismal process), GO:0051239 (regulation of multicellular organismal process), GO:2000026 (regulation of multicellular organismal development), GO:1904018 (positive regulation of vasculature development), GO:0022603 (regulation of anatomical structure morphogenesis), GO:1901342 (regulation of vasculature development), GO:0045766 (positive regulation of angiogenesis), GO:0045765 (regulation of angiogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: HPt domain-containing protein (Q9HYQ0)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Not known
InterPro domains:
- IPR036641: HPT domain superfamily (homologous_superfamily) [1-113]
- IPR008207: Signal transduction histidine kinase, phosphotransfer (Hpt) domain (domain) [18-116]
Sequence:
MSAPHLDDRVLASLQEVMEDEYPVLLDTFVLDSEERLRSLHAALQAGDAQALRHTAHSFKGGSSNMGAVLLAGYCKELEESARRGELQRAPALIEQMEREFAIVRILFKQERQRYR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0060089 (molecular transducer activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023056 (positive regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0010647 (positive regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0010646 (regulation of cell communication)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005618 (cell wall), GO:0009277 (fungal-type cell wall)
Protein: GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (A0A1W2PRH3)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|RuleBase:RU367138}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU367138}.
InterPro domains:
- IPR017850: Alkaline-phosphatase-like, core domain superfamily (homologous_superfamily) [44-340]
- IPR002591: Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase (family) [46-268]
- IPR037671: GPI ethanolamine phosphate transferase 1, N-terminal (domain) [40-321]
- IPR007070: GPI ethanolamine phosphate transferase 1 (family) [2-371]
Sequence:
MLLFFTLGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPARRLVLFVADGLRADALYELDENGNSRAPFIRNIIMHEGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAKREDFGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPSSRDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQGILPVDYLNNTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFNCAGS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016780 (phosphotransferase activity, for other substituted phosphate groups)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006629 (lipid metabolic process), GO:0019637 (organophosphate metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006793 (phosphorus metabolic process), GO:0046470 (phosphatidylcholine metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0046486 (glycerolipid metabolic process), GO:0006644 (phospholipid metabolic process), GO:0090407 (organophosphate biosynthetic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0008610 (lipid biosynthetic process), GO:0045017 (glycerolipid biosynthetic process), GO:0006650 (glycerophospholipid metabolic process), GO:0008654 (phospholipid biosynthetic process), GO:0006656 (phosphatidylcholine biosynthetic process), GO:0046474 (glycerophospholipid biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0005886 (plasma membrane)