lokahq/bioreason-rl huggingface dataset:
Protein: Probable plastid-lipid-associated protein 13, chloroplastic (Fibrillin-7b) (AtPGL30) (Q8S9M1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Plastid, chloroplast, plastoglobule {ECO:0000269|PubMed:16461379, ECO:0000269|PubMed:22274653}.
InterPro domains:
- IPR039633: Plastid-lipid-associated protein (family) [45-285]
- IPR006843: Plastid lipid-associated protein/fibrillin conserved domain (domain) [93-277]
Sequence:
MALIHGSVPGTSAVRLVFSTSASPSRFCLNVPVVKQGWKNSCRRRVLRAMVQETVQGSPLVYAREMERLSAKESLLLALKDAGGFEALVTGKTTNMQRIDVNERITSLERLNPTPRPTTSPCFEGRWNFEWFGSGSPGLLAARVIFERFPSTLANLSRMEILIKDANAKATANIKLLNSIESKIILSSKLTVEGPLRLKEEYVEGMLETPTVIEEAVPEQLKSALGQAATTLQQLPALIKDTLASGLRIPLSGSFERFFMISYLDEEILIVRDTEGVPEVLTRIETPSSTVVETIEYDS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0009314 (response to radiation), GO:0071214 (cellular response to abiotic stimulus), GO:0104004 (cellular response to environmental stimulus), GO:0071478 (cellular response to radiation), GO:0009416 (response to light stimulus), GO:0071482 (cellular response to light stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009532 (plastid stroma), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005829 (cytosol), GO:0010287 (plastoglobule), GO:0031975 (envelope), GO:0005737 (cytoplasm), GO:0031977 (thylakoid lumen), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0034357 (photosynthetic membrane), GO:0043229 (intracellular organelle), GO:0019867 (outer membrane), GO:0009536 (plastid), GO:0043228 (non-membrane-bounded organelle), GO:0043227 (membrane-bounded organelle), GO:0009570 (chloroplast stroma), GO:0009507 (chloroplast), GO:0042651 (thylakoid membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031976 (plastid thylakoid), GO:0098588 (bounding membrane of organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0009526 (plastid envelope), GO:0042170 (plastid membrane), GO:0031968 (organelle outer membrane), GO:0009579 (thylakoid), GO:0055035 (plastid thylakoid membrane), GO:0009535 (chloroplast thylakoid membrane), GO:0009534 (chloroplast thylakoid)
Protein: At3g23190 (HR-like lesion-inducing protein) (Q9LTC9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
InterPro domains:
- IPR008637: HR-like lesion-inducer (family) [18-198]
Sequence:
MEKTQESVVRYGKKIEKMPYLMPAGRVVFASAFLVSAWREYYGFGLAADELRPKLGFFENQAKAIVALGILMKFVGGILFIFNTYVGAALLLVYQAILSPILYDFYNRDYDRDHFTVFYTKFKEFVEETTSADGGVAMSLYTSVVNEESRQKFIDQLNEIARIAISNPLFTPSDFNTLFIRFIKGVGIAAALACFIAMKHRHAVLIEKTSKKQKTN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044237 (cellular metabolic process), GO:0061919 (process utilizing autophagic mechanism), GO:0009056 (catabolic process), GO:0016043 (cellular component organization), GO:0044248 (cellular catabolic process), GO:0006914 (autophagy), GO:0016236 (macroautophagy), GO:0000422 (autophagy of mitochondrion), GO:0006996 (organelle organization), GO:0022411 (cellular component disassembly), GO:0007005 (mitochondrion organization), GO:0000423 (mitophagy), GO:0061912 (selective autophagy), GO:1903008 (organelle disassembly), GO:0061726 (mitochondrion disassembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Dishevelled binding antagonist of beta catenin 3 (Thymus expressed gene 3-like, isoform CRA_b) (G5E9H6)
Organism: Homo sapiens (Human)
Function: Not known
InterPro domains:
- IPR024843: Dapper (family) [1-168]
Sequence:
MIRAFSFPVSPERGRLRGWLEGSLAGLCELHWLRERQEYRVQQALRLAQPGMGGAEAEDEEDADEDEDAAAARRAAAALEEQLEALPGLVWDLGQQLGDLSLESGGLEQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGKVGEGGALGPGKGQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023057 (negative regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0010646 (regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0030111 (regulation of Wnt signaling pathway), GO:0030178 (negative regulation of Wnt signaling pathway), GO:0090090 (negative regulation of canonical Wnt signaling pathway), GO:0060828 (regulation of canonical Wnt signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Replication initiator 1 (C9JYJ8)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
InterPro domains:
- IPR013087: Zinc finger C2H2-type (domain) [117-379]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [126-370]
Sequence:
MDGRRVPAQPAAEFSLTPGGYRSVGRSRRCSRGSIPRNIPKRSWKKPHPQLCSLQAEEEPMLERRCRGPLAMGLAQPRLLSGPSQESPQTLGKESRGLRQQGTSVAQSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0006259 (DNA metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0006260 (DNA replication)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1) (Q91Y77)
Organism: Rattus norvegicus (Rat)
Function: Sodium- and proton-independent thyroid hormones and aromatic acids transporter. Mediates both uptake and efflux of 3,5,3'-triiodothyronine (T3) and 3,5,3',5'-tetraiodothyronine (T4) with high affinity, suggesting a role in the homeostasis of thyroid hormone levels (By similarity). Responsible for low affinity bidirectional transport of the aromatic amino acids, such as phenylalanine, tyrosine, tryptophan and L-3,4-dihydroxyphenylalanine (L-dopa). Plays an important role in homeostasis of aromatic amino acids (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q8TF71}; Multi-pass membrane protein {ECO:0000255}. Basolateral cell membrane {ECO:0000269|PubMed:11278508}; Multi-pass membrane protein {ECO:0000255}. Note=In the epithelial cells is detected in the basolateral membrane but not in the apical membrane.
InterPro domains:
- IPR050327: Proton-linked Monocarboxylate Transporter (family) [65-472]
- IPR036259: MFS transporter superfamily (homologous_superfamily) [58-506]
- IPR020846: Major facilitator superfamily domain (domain) [291-514]
- IPR011701: Major facilitator superfamily (family) [302-486]
Sequence:
MVPSQEEPAAAERETNEAQPPGPAPSDDAPLPVPGPSDVSDGSVEKVEVELTRSTGNQEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNAYGVLFVSMLETFGAKDDDNMAFKAAWVGSLSMGMIFFCCPIVSVFTDMFGCRRTAVLGAAVGFVGLMSSSFVSSIEPLYFTYGVVFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLGNLTSTVGLCYTLRILCIFMFVLFLAGFTYRPLVPSSKEKESEDSRSSFFSRRKLSPPKKIFNFALFKETAYAVWAAGIPLALFGYFVPYVHLMNHVKERFKDVNNKEVLFMCIGVTSGVGRLLFGRIADYLPGVKKVYLQVLSFFFIGLTSMMIPLCSVFGALIALCLIMGLFDGCFISIMAPIAFELVGPQDASQAIGFLLGFMSIPMTVGPPVAGLLHDKLGSYDLAFYLAGIPPFIGGAVLCLIPWIHSKKQREISKNTGGEKMEKMLANQSSLLSSSSGIFKKESDSII
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0015291 (secondary active transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0065008 (regulation of biological quality), GO:0010817 (regulation of hormone levels), GO:0006810 (transport), GO:0009914 (hormone transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0045178 (basal part of cell), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0009925 (basal plasma membrane), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0016323 (basolateral plasma membrane)
Protein: Tubulin alpha-3D chain (EC 3.6.5.-) (Alpha-tubulin 3D) [Cleaved into: Detyrosinated tubulin alpha-3D chain] (P0DPH8)
Organism: Homo sapiens (Human)
Function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
Subcellular location: Cytoplasm, cytoskeleton.
InterPro domains:
- IPR036525: Tubulin/FtsZ, GTPase domain superfamily (homologous_superfamily) [1-268]
- IPR023123: Tubulin, C-terminal (homologous_superfamily) [384-436]
- IPR008280: Tubulin/FtsZ, C-terminal (homologous_superfamily) [246-437]
- IPR018316: Tubulin/FtsZ, 2-layer sandwich domain (domain) [248-393]
- IPR000217: Tubulin (family) [2-439]
- IPR002452: Alpha tubulin (family) [18-438]
- IPR017975: Tubulin, conserved site (conserved_site) [142-148]
- IPR003008: Tubulin/FtsZ, GTPase domain (domain) [3-246]
- IPR037103: Tubulin/FtsZ-like, C-terminal domain (homologous_superfamily) [269-383]
Sequence:
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEAEEGEEY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0007017 (microtubule-based process), GO:0051641 (cellular localization), GO:0051301 (cell division), GO:0046907 (intracellular transport), GO:0051649 (establishment of localization in cell), GO:0006810 (transport), GO:0030705 (cytoskeleton-dependent intracellular transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0005634 (nucleus), GO:0015630 (microtubule cytoskeleton)
Protein: Probable methylmalonyl-CoA mutase small subunit (MCM) (EC 5.4.99.2) (P9WJK7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
InterPro domains:
- IPR004608: Methylmalonyl-CoA mutase, small subunit (family) [5-615]
- IPR016176: Cobalamin (vitamin B12)-dependent enzyme, catalytic (homologous_superfamily) [33-518]
- IPR036724: Cobalamin-binding domain superfamily (homologous_superfamily) [466-615]
- IPR006099: Methylmalonyl-CoA mutase, alpha/beta chain, catalytic (domain) [48-524]
Sequence:
MSIDVPERADLEQVRGRWRNAVAGVLSKSNRTDSAQLGDHPERLLDTQTADGFAIRALYTAFDELPEPPLPGQWPFVRGGDPLRDVHSGWKVAEAFPANGATADTNAAVLAALGEGVSALLIRVGESGVAPDRLTALLSGVYLNLAPVILDAGADYRPACDVMLALVAQLDPGQRDTLSIDLGADPLTASLRDRPAPPIEEVVAVASRAAGERGLRAITVDGPAFHNLGATAATELAATVAAAVAYLRVLTESGLVVSDALRQISFRLAADDDQFMTLAKMRALRQLWARVAEVVGDPGGGAAVVHAETSLPMMTQRDPWVNMLRCTLAAFGAGVGGADTVLVHPFDVAIPGGFPGTAAGFARRIARNTQLLLLEESHVGRVLDPAGGSWFVEELTDRLARRAWQRFQAIEARGGFVEAHDFLAGQIAECAARRADDIAHRRLAITGVNEYPNLGEPALPPGDPTSPVRRYAAGFEALRDRSDHHLARTGARPRVLLLPLGPLAEHNIRTTFATNLLASGGIEAIDPGTVDAGTVGNAVADAGSPSVAVICGTDARYRDEVADIVQAARAAGVSRVYLAGPEKALGDAAHRPDEFLTAKINVVQALSNLLTRLGA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0006629 (lipid metabolic process), GO:0019541 (propionate metabolic process), GO:0006082 (organic acid metabolic process), GO:0006631 (fatty acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0046459 (short-chain fatty acid metabolic process), GO:0032787 (monocarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Cinnamyl alcohol dehydrogenase 7 (OsCAD7) (EC 1.1.1.195) (Protein FLEXIBLE CULM 1) (Q0JA75)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Involved in lignin biosynthesis. May catalyze the final step specific for the production of lignin monomers, like coniferyl alcohol, sinapyl alcohol and 4-coumaryl alcohol.
InterPro domains:
- IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [175-340]
- IPR020843: Enoylreductase domain (domain) [28-370]
- IPR013149: Alcohol dehydrogenase-like, C-terminal (domain) [213-336]
- IPR011032: GroES-like superfamily (homologous_superfamily) [28-204]
- IPR013154: Alcohol dehydrogenase-like, N-terminal (domain) [46-164]
- IPR002328: Alcohol dehydrogenase, zinc-type, conserved site (conserved_site) [81-95]
- IPR047109: Cinnamyl alcohol dehydrogenase-like (family) [18-375]
Sequence:
MAPTTTATAAAEQAPPPQHTRKAVGLAAHDDSGHLTPIRISRRKTGDDDVAIKVLYCGICHSDLHTIKNEWRNAVYPVVAGHEITGVVTEVGKNVARFKAGDEVGVGCMVNTCGGCESCRDGCENYCSGGVVFTYNSVDRDGTRTYGGYSDAVVVSQRFVVRFPSSAGGGAGAALPLDSGAPLLCAGVTVYAPMRQHGLCEAGKHVGVVGLGGLGHVAVKFARAFGMRVTVISTSPVKRQEALERLGADGFIVSTNASEMKAAMGTMHGIINTASASTSMHSYLALLKPKGKMILVGLPEKPLQIPTFALVGGGKILAGSCMGSISETQEMIDFAAEHGVAADIELIGADEVNTAMERLAKGDVRYRFVVDIGNTLRSD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0019748 (secondary metabolic process), GO:0071704 (organic substance metabolic process), GO:0044550 (secondary metabolite biosynthetic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0009698 (phenylpropanoid metabolic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0009808 (lignin metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0009699 (phenylpropanoid biosynthetic process), GO:0009809 (lignin biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Hydroxyacylglutathione hydrolase, cytoplasmic isozyme (EC 3.1.2.6) (Glyoxalase II) (Glx II) (Q05584)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:9261170}.
InterPro domains:
- IPR001279: Metallo-beta-lactamase (domain) [14-188]
- IPR032282: Hydroxyacylglutathione hydrolase, C-terminal domain (domain) [189-274]
- IPR035680: Hydroxyacylglutathione hydrolase, MBL domain (domain) [16-188]
- IPR036866: Ribonuclease Z/Hydroxyacylglutathione hydrolase-like (homologous_superfamily) [1-272]
Sequence:
MQVKSIKMRWESGGVNYCYLLSDSKNKKSWLIDPAEPPEVLPELTEDEKISVEAIVNTHHHYDHADGNADILKYLKEKNPTSKVEVIGGSKDCPKVTIIPENLKKLHLGDLEITCIRTPCHTRDSICYYVKDPTTDERCIFTGDTLFTAGCGRFFEGTGEEMDIALNNSILETVGRQNWSKTRVYPGHEYTSDNVKFVRKIYPQVGENKALDELEQFCSKHEVTAGRFTLKDEVEFNPFMRLEDPKVQKAAGDTNNSWDRAQIMDKLRAMKNRM
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0016790 (thiolester hydrolase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0009056 (catabolic process), GO:0042180 (cellular ketone metabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:0044282 (small molecule catabolic process), GO:1901575 (organic substance catabolic process), GO:0006081 (cellular aldehyde metabolic process), GO:0044248 (cellular catabolic process), GO:0006082 (organic acid metabolic process), GO:0006089 (lactate metabolic process), GO:0042182 (ketone catabolic process), GO:0046185 (aldehyde catabolic process), GO:0009438 (methylglyoxal metabolic process), GO:0043436 (oxoacid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0051596 (methylglyoxal catabolic process), GO:0032787 (monocarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005739 (mitochondrion), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005759 (mitochondrial matrix), GO:0070013 (intracellular organelle lumen)
Protein: Cytochrome P450 2M1 (EC 1.14.14.1) (CYPIIM1) (LMC1) (Lauric acid omega-6-hydroxylase) (Q92088)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Function: Has (omega-6)-hydroxylation activity toward lauric acid.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Microsome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
InterPro domains:
- IPR036396: Cytochrome P450 superfamily (homologous_superfamily) [27-499]
- IPR017972: Cytochrome P450, conserved site (conserved_site) [434-443]
- IPR001128: Cytochrome P450 (family) [37-484]
- IPR002401: Cytochrome P450, E-class, group I (family) [65-464]
- IPR050182: Cytochrome P450 family 2 (family) [17-475]
Sequence:
MDVLHILQTNFVSIIIGFVVIILLWMNRGKQSNSRLPPGPAPIPLLGNLLRMDVKAPYKLYMELSKKYGSVFTVWLGSKPVVVISGYQAIKDAFVTQGEEFSGRANYPVIMTVSKGYGVLVSSGKRSKDLRRFSLMTLKTFGMGRRSIEERVQEEAKMLVKAFGEYRDSVVNPKELLCNCVGNVICSIVFGHRFENDDPMFQLIQKAVDAYFNVLSSPIGAMYNMFPRIVWCFPGNHHEMFAIVNKAKVYIQEQAEIRLKTLNISEPQDFIEAFLVKMLEEKDDPNTEFNNGNMVMTAWSLFAAGTETTSSTLRQSFLMMIKYPHIQESVQKEIDEVIGSRVPTVDDRVKMPYTDAVIHEVQRYMDLSPTSVPHKVMRDTEFYNYHIPEGTMVLPLLSSVLVDPKLFKNPDEFDPENFLDENGVFKKNDGFFAFGVGKRACPGEALARVELFLFFTSVLQRFTFTGTKPPEEINIEPACSSFGRLPRSYDCYIKLRTEK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0004497 (monooxygenase activity), GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen), GO:0008391 (arachidonic acid monooxygenase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0006629 (lipid metabolic process), GO:0006082 (organic acid metabolic process), GO:0006631 (fatty acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0051791 (medium-chain fatty acid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0032787 (monocarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)