lokahq/bioreason-rl huggingface dataset:
Protein: Lipopolysaccharide heptosyltransferase 2 (EC 2.4.99.24) (ADP-heptose:lipopolysaccharide heptosyltransferase II) (ADP-heptose:LPS heptosyltransferase II) (Heptosyltransferase II) (P37421)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function: Not known
InterPro domains:
- IPR051199: Lipopolysaccharide/Lipooligosaccharide Heptosyltransferase (family) [1-345]
- IPR002201: Glycosyl transferase, family 9 (family) [2-340]
- IPR011910: ADP-heptose--LPS heptosyltransferase 2 (family) [2-343]
Sequence:
MKILVIGPSWVGDMMMSQSLYRTLKARYPQAIIDVMAPAWCRPLLSRMPEVNEAIPMPLGHGALEIGERRRLGHSLREKRYDRAWVLPNSFKSALIPFFANIPHRTGWRGEMRYGLLNDARVLDKDAWPLMVERYVALAYDKGVMRAAKDLPQPLLWPQLQVSEGEKSLMCSDFSLSSERPLIGFCPGAEFGPAKRWPHYHYAELAKQLINEGYQVVLFGSAKDHEAGNEILAALNSEQQAWCRNLAGETQLEQAVILIAACKAIVTNDSGLMHVAAALDRPLVALYGPSSPDFTPPLSHKARVIRLITGYHKVRKGDTAQGYHQSLIDITPQRVLEELHSLLSEEGV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0005975 (carbohydrate metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0044262 (cellular carbohydrate metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:0009311 (oligosaccharide metabolic process), GO:0016051 (carbohydrate biosynthetic process), GO:0005976 (polysaccharide metabolic process), GO:0034637 (cellular carbohydrate biosynthetic process), GO:1903509 (liposaccharide metabolic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0008653 (lipopolysaccharide metabolic process), GO:0044264 (cellular polysaccharide metabolic process), GO:0009103 (lipopolysaccharide biosynthetic process), GO:0009312 (oligosaccharide biosynthetic process), GO:0033692 (cellular polysaccharide biosynthetic process), GO:0000271 (polysaccharide biosynthetic process), GO:0046401 (lipopolysaccharide core region metabolic process), GO:0009244 (lipopolysaccharide core region biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031469 (bacterial microcompartment)
Protein: aspartate transaminase (EC 2.6.1.1) (Q7K221)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
InterPro domains:
- IPR015421: Pyridoxal phosphate-dependent transferase, major domain (homologous_superfamily) [63-305]
- IPR004839: Aminotransferase, class I/classII, large domain (domain) [29-397]
- IPR015424: Pyridoxal phosphate-dependent transferase (homologous_superfamily) [1-401]
- IPR015422: Pyridoxal phosphate-dependent transferase, small domain (homologous_superfamily) [7-397]
- IPR000796: Aspartate/other aminotransferase (family) [2-402]
Sequence:
MSIYADVPKGPAIEVFALTQAFKDDSNPNKVNLSVGAYRTDAGVPWVLPVVRKTEISIASDEQVNHEYLPVTGLETFTNAATELVLGADSPAIKENRAFGVQTISGTGALRVAADFLHTQLNRNVVYYSNPTWENHHKIFCDAGFTTVKSYRYWDQNKRELDFKNMLADLNDAPPGAVIILHACAHNPTGIDPTQEQWTELADLMEKKKLFPLFDSAYQGFASGDPDRDAWAARYFVQRGFELFICQSFAKNFGLYCERTGNLAVVQKNGATKAAVHSQLTLLIRGQYSNPPAYGARIVSKVLNTPELRKEWMASIQAMSSRIREMRTALRDKLVALGTPGTWDHIVNQIGMFSYTGLNESHVRVLIDQYHIYLLKTGRISMSGLNKGNVEYVAKAIHAAVTGSGESASCPCENKL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016769 (transferase activity, transferring nitrogenous groups), GO:0008483 (transaminase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0006082 (organic acid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006520 (amino acid metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006536 (glutamate metabolic process), GO:0008652 (amino acid biosynthetic process), GO:0016053 (organic acid biosynthetic process), GO:0043436 (oxoacid metabolic process), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:1901605 (alpha-amino acid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0006537 (glutamate biosynthetic process), GO:1901607 (alpha-amino acid biosynthetic process), GO:0009064 (glutamine family amino acid metabolic process), GO:0046394 (carboxylic acid biosynthetic process), GO:0043650 (dicarboxylic acid biosynthetic process), GO:0009084 (glutamine family amino acid biosynthetic process), GO:0043648 (dicarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: GH05406p (Mitochondrial ribosomal protein S30, isoform A) (Mitochondrial ribosomal protein S30, isoform B) (Q9VXP3)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
InterPro domains:
- IPR039982: Large ribosomal subunit protein mL65 (family) [10-457]
- IPR010793: Large ribosomal subunit protein mL37/mL65 (family) [6-445]
Sequence:
MLKLNRVRHLRTTYKRCLSGQSQLQLNSTDAEPAYPEIQDLSFKARKQKDAANWHEEIRQVPTVEEKMIKINMPRYYGFKVVDFNDSKIPYNALPLTQHYTRTVLEDLPSETDKKAQAKDSEQEQEQPSVDGLFKAARGDVIDALEFAHDYYKHLEKQHNSAESNPVERERILTQIIVEQLNRALLQSLSEEYKHLDELDVDYNPRHEAFWAVGGVDPPKNVQKSKKGREWQKDMANESVDRMVQYTGAPYLALRHRKQLTPWKTEAESENLELSKQLPRFKHDPRTLGYSTKHQHATNVPGYWPKGNENNFGLLSFQSRAHLQIRPKSFGEQDQLEALHSLAIKSSYAWLLAQANYNGFNTYNELTYPMNTQTVITNGREWSFYEYQLNTLLLHGTNVAENPRVNFCRGTKPLPLYAEISASGKCVDFNDNALRHLLNFYANAPSIQRSIGEQQPYVASDVSAYENAEQRDFINKTFKYLASNRPRHLELPEIYLWEKLYKIDNNNRAMEAKRRFFELDINPWQRTLDTHDKEYVPRAVRPDVPKNKNRFKKTYYP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0003735 (structural constituent of ribosome)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0019538 (protein metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006412 (translation), GO:0009059 (macromolecule biosynthetic process), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:0006518 (peptide metabolic process), GO:0010467 (gene expression), GO:0140053 (mitochondrial gene expression), GO:0043043 (peptide biosynthetic process), GO:0032543 (mitochondrial translation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Amidase enhancer (Q55763)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Function: Not known
InterPro domains:
- IPR051922: Bacterial Sporulation-Associated (family) [72-522]
- IPR013486: Sporulation stage II protein D, amidase enhancer LytB (family) [229-522]
- IPR013693: Sporulation stage II protein D, amidase enhancer LytB N-terminal (domain) [225-314]
Sequence:
MFISPPRNLLKVAVQRVGGLVIALGLVAGGALPSFAKDVLLQVGVVQRFGDEDRDQLTISGVGNDDLTFTAVNNQGEKVTLQGKQGTIAISRRAVPRKLAEVLVLGDHATFETAEDDALRWQAQGIAVEVTQPGRWQVWAKRDVYDSPLVRRWLLADLKKQGHQLPYLESVLLDSKPQAMVVINGQSYPADRVTVTAAKNQIQVTEGEKKFVYGGWLQLQPNSYGNYTLVNHVPLETYLRGVVPHEIGPGAPPTAAKAQTIIARTYALQNRRRFAADGYELCATTHCQVYYGLSGTTPRADEAIKETAGQVLTYNNQLVDALYSSTAGGVTAKFSDVWNGEERPYLQAVIDSAQPIWNLSTQSLADEATFRKFINLQEGFNETGRKFLRWRYPATLAELNQDLKKYLTNRRHPLADFTTIYDMKVTRRSPSGRILLLEVLTDKGVVELAKNEARSAFGPPRSTLFYLEPTYDANQRLQSVFFVGGGFGHGVGMSQFGSYKLSQLGWSAEQILAFYYPGTQIRQLNEQILGQTPRP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006520 (amino acid metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044283 (small molecule biosynthetic process), GO:0006082 (organic acid metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0008652 (amino acid biosynthetic process), GO:0016053 (organic acid biosynthetic process), GO:0043436 (oxoacid metabolic process), GO:1901605 (alpha-amino acid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0009064 (glutamine family amino acid metabolic process), GO:0046394 (carboxylic acid biosynthetic process), GO:1901607 (alpha-amino acid biosynthetic process), GO:0009084 (glutamine family amino acid biosynthetic process), GO:0006525 (arginine metabolic process), GO:0006526 (arginine biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0031975 (envelope), GO:0042597 (periplasmic space), GO:0030313 (cell envelope), GO:0030288 (outer membrane-bounded periplasmic space)
Protein: Probable 26S proteasome regulatory subunit p28 (Proteasome non-ATPase subunit 6) (P50086)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Acts as a chaperone during the assembly of the 26S proteasome, specifically of the 19S regulatory complex (RC) and appears to have an overlapping role with RPN14.
InterPro domains:
- IPR036770: Ankyrin repeat-containing domain superfamily (homologous_superfamily) [1-228]
- IPR002110: Ankyrin repeat (repeat) [1-206]
Sequence:
MSNYPLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAEYDLVDNKGAKAEDVALNEQVKKFFLNNV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0043412 (macromolecule modification), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0009451 (RNA modification), GO:0006400 (tRNA modification), GO:0034470 (ncRNA processing), GO:0034660 (ncRNA metabolic process), GO:0006399 (tRNA metabolic process), GO:0008033 (tRNA processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: COP9 signalosome complex subunit 4 (CSN complex subunit 4) (SGN4) (O13895)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11854407}. Nucleus {ECO:0000269|PubMed:11854407}.
InterPro domains:
- IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [14-230]
- IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [293-357]
- IPR040134: 26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 (family) [96-373]
- IPR000717: Proteasome component (PCI) domain (domain) [190-371]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [291-352]
Sequence:
MEEVVHYFLEGNMPVAQFREALALHYTNEKELFEQAKRCLNICCGSNNFAKRNDVLFSLLDVAVSISSLELRKELISELYVPVQSLEEAPSEYLVSCCLQLATIYEAEQNFELLCSSLEAVEKHGHFENDLEQLLLLRIRLGDAYLKLGKAEKAILTVRTSIPLAFKVSNDQLLMELQLCNARALDETGQFLEAAKCYYRVLQYKVPGNELIYRENLCSVAQCLLLAIPSPIVLQFLQEISLQPSVREIPFYSLVEKYLKRKFIGKEDGAFLLPFLLPHQVIHMNRLIEDGRHFLETNILFLSEFFEVSSTSILAKHFKLSEEQVDTVVADMVIQERLNASIDQCEGYITFLPEYGKANNLPNYVNKIATVLQHYGS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0044248 (cellular catabolic process), GO:0009057 (macromolecule catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0006508 (proteolysis), GO:0044265 (cellular macromolecule catabolic process), GO:0030163 (protein catabolic process), GO:0043632 (modification-dependent macromolecule catabolic process), GO:0010498 (proteasomal protein catabolic process), GO:0051603 (proteolysis involved in protein catabolic process), GO:0019941 (modification-dependent protein catabolic process), GO:0043161 (proteasome-mediated ubiquitin-dependent protein catabolic process), GO:0006511 (ubiquitin-dependent protein catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: UPF0538 protein C2C4.04c (O14037)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Not known
InterPro domains:
- IPR018794: Uncharacterised protein family UPF0538 (family) [2-124]
Sequence:
MTGATLTVRVIRNFEYRTLKNVVFHDIDLATTTVDQFKKIIDERIQTDPSLKIYRTTHFDTLKIYVKAQQHKTQNLAINLDHDDWILNDGAKTLSLCGIENETELSYFELAAYKAYQANPVQKWL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0008380 (RNA splicing), GO:0006397 (mRNA processing), GO:0016071 (mRNA metabolic process), GO:0000398 (mRNA splicing, via spliceosome), GO:0000375 (RNA splicing, via transesterification reactions), GO:0045292 (mRNA cis splicing, via spliceosome), GO:0000377 (RNA splicing, via transesterification reactions with bulged adenosine as nucleophile)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (GNT-I) (GlcNAc-T I) (EC 2.4.1.101) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I) (G5EBG7)
Organism: Caenorhabditis elegans
Function: Not known
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU368119}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU368119}.
InterPro domains:
- IPR029044: Nucleotide-diphospho-sugar transferases (homologous_superfamily) [70-401]
- IPR004139: Glycosyl transferase, family 13 (family) [40-401]
- IPR052261: Glycosyltransferase 13 (family) [44-415]
Sequence:
MKRVLRRSASKHASTLFKIICILVLCSFIIYLKSEDHDLQKNTAIHAPRSNSREDEDDILIPADNKDQQFVAAVLVFCATRPDALRNHLSQILAQRPSHFQYHIIVSQDGNKTAVTQVAQKFVKDYKNVSHIQHEKTEIKKRNNYPAISAHYKWALDKAFKGFRYDHVIVTEDDLDIGNDFFSYFRWGKQVLNSDDTIWCVSAWNDNGGGPLIDSTRGDLIWRTDFFPGLGWMLTKKLWNELSPGFPVAYWDDWMRKPEVRKSRSCIRPEISRTSHNMKLAGKGSSGGMFKDYLSKISASSANIDFSLLPVTLVQKSIYDKRLIEQIENARPIDLQNTTGMEKTYNYKIVYKNIRDWHRLAAHFKLMTDIRGGMQRTAYYGVVTLMFQNCRVFLVPESTYRNPSQLTSYVYDSEWDKQNRFIEFEAYYCKTKKYAGKCDPHSPEMIAFFKKKGWKKRLDDWGEMLVV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016757 (glycosyltransferase activity), GO:0140103 (catalytic activity, acting on a glycoprotein), GO:0016758 (hexosyltransferase activity), GO:0008194 (UDP-glycosyltransferase activity), GO:0008375 (acetylglucosaminyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0070085 (glycosylation), GO:0044249 (cellular biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0043413 (macromolecule glycosylation), GO:1901135 (carbohydrate derivative metabolic process), GO:0019538 (protein metabolic process), GO:0036211 (protein modification process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0009059 (macromolecule biosynthetic process), GO:0006486 (protein glycosylation), GO:0043412 (macromolecule modification), GO:0034645 (cellular macromolecule biosynthetic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0009100 (glycoprotein metabolic process), GO:0006487 (protein N-linked glycosylation), GO:0009101 (glycoprotein biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure), GO:0048471 (perinuclear region of cytoplasm)
Protein: Lysozyme 1 (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase) (Q27650)
Organism: Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM)
Function: Has antibacterial activity against Gram-positive bacteria. No activity against S.aureus. Does not appear to have chitinase activity.
Subcellular location: Cytoplasmic granule {ECO:0000269|PubMed:7649184}.
InterPro domains:
- IPR002053: Glycoside hydrolase, family 25 (family) [13-211]
- IPR017853: Glycoside hydrolase superfamily (homologous_superfamily) [13-210]
- IPR051595: Glycosyl Hydrolase 25 Enzymes (family) [3-211]
Sequence:
MFALFLCIALASAKLGIDVSQPTSTSSFTCLRNKGFTTMVIVRAWKSTGSFDTNAPQTLKNANAAGFSIENSDVYYYPCISCGNMAGQVRTFWQKVGQYSLKVKRVWFDIEGTWTSSVSTNQNYLMQMMNEARAIGIVHGIYGSKYYWGNLFGSSYKYAYASSTPLWYPHYDNSPSFSDFSSFGGWTSPSMKQYRGDVSVCSAGVDYNYKP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0030246 (carbohydrate binding), GO:0016787 (hydrolase activity), GO:0030247 (polysaccharide binding), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:0009615 (response to virus), GO:0043207 (response to external biotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0005576 (extracellular region), GO:0043227 (membrane-bounded organelle), GO:0043230 (extracellular organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:1903561 (extracellular vesicle)