Protein: S-(+)-linalool synthase, chloroplastic (OsLIS) (EC 4.2.3.25) (Q6ZH94)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Involved in monoterpene (C10) biosynthesis. The major product is S-(+)-linalool. Linalool production is induced by jasmonate in response to pathogen attack, it possesses antibacterial activity and is important for resistance to the bacterial blight pathogen Xanthomonas oryzae pv. oryzae (Xoo). Plants over-expressing linalool synthase display enhanced resistance to Xoo.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:23889289}.
InterPro domains:
- IPR008930: Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid (homologous_superfamily) [68-259]
- IPR005630: Terpene synthase, metal-binding domain (domain) [298-537]
- IPR001906: Terpene synthase, N-terminal domain (domain) [77-240]
- IPR008949: Isoprenoid synthase domain superfamily (homologous_superfamily) [271-595]
- IPR034741: Terpene cyclase-like 1, C-terminal domain (domain) [272-577]
- IPR050148: Terpene synthase-like (family) [65-578]
- IPR036965: Terpene synthase, N-terminal domain superfamily (homologous_superfamily) [79-280]
Sequence:
MVCHVFSSFSSSLIRVLEAPLLLPAASASSSSSSSPASRSGGRRRRAAHVRPSPAIYPGRQELASHSSMLPTDFDIKVLIERHEALTDDVQEMLQHQRRRHQKTASGGRERIATVDHLRRLCMDHYFQDEVDDAMDACLLEELAHGGDLLDATLAFRLMREAGHHVSADEVLGRFTDDNGEFRLDYRKDIRGLLSLQDISHMNIGQEASLCKAKEFSTRNLESAINYLEPNLARYVRQSLDHPYHVSLNQYKARHHLSYLQTLPIRCTAMEELALADFQLNKLLHQMEMQEIKRWWMDLGLAQEIPVARDQVQKWFVWMMTAIQGASLSRCRIELTKIVSFVYIVDDIFDLVGTREELSCFTQAIRMWDLAAADSLPSCMRSCFRALHTVTNDIADMVEREHGVNPINHLKKAWAMLFDGFMTETKWLSAGQVPDSEEYLRNGVVTSGVPLVFVHLLFMLGHDVSQNAAEFVDHIPPVISCPAKILRLWDDLGSAKDEAQEGLDGSYKELYLKENPGLAAGEAEEHVRRLIAGEWEELNRECFSASPSRSSPATTFPAGFTQAALNAARMVGVMYGYDGERRLPVLDDYVRMLLF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016835 (carbon-oxygen lyase activity), GO:0016838 (carbon-oxygen lyase activity, acting on phosphates), GO:0010333 (terpene synthase activity), GO:0010334 (sesquiterpene synthase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0048511 (rhythmic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0007623 (circadian rhythm), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0120252 (hydrocarbon metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0006082 (organic acid metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006631 (fatty acid metabolic process), GO:0006720 (isoprenoid metabolic process), GO:0120251 (hydrocarbon biosynthetic process), GO:0043436 (oxoacid metabolic process), GO:0042214 (terpene metabolic process), GO:0008299 (isoprenoid biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0043692 (monoterpene metabolic process), GO:0019372 (lipoxygenase pathway), GO:0006721 (terpenoid metabolic process), GO:0016114 (terpenoid biosynthetic process), GO:0046246 (terpene biosynthetic process), GO:0033073 (pinene metabolic process), GO:0032787 (monocarboxylic acid metabolic process), GO:0006690 (icosanoid metabolic process), GO:0043693 (monoterpene biosynthetic process), GO:0010597 (green leaf volatile biosynthetic process), GO:0018867 (alpha-pinene metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle)