lokahq/bioreason-rl huggingface dataset:
Protein: Multidrug efflux pump accessory protein AcrZ (AcrAB-TolC multidrug efflux pump accessory protein AcrZ) (Acridine resistance protein Z) (P0AAW9)
Organism: Escherichia coli (strain K12)
Function: AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_01484, ECO:0000269|PubMed:19121005, ECO:0000269|PubMed:21778229}; Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01484, ECO:0000269|PubMed:19121005, ECO:0000269|PubMed:21778229}. Note=In sucrose cushions fractionates with both the inner and outer membranes.
InterPro domains:
- IPR019702: Multidrug efflux pump accessory protein AcrZ (family) [1-47]
- IPR053730: Multidrug Efflux Pump Accessory AcrZ (homologous_superfamily) [1-49]
Sequence:
MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQPGQNH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0007154 (cell communication), GO:0009991 (response to extracellular stimulus), GO:0031668 (cellular response to extracellular stimulus), GO:0042594 (response to starvation), GO:0071496 (cellular response to external stimulus), GO:0033554 (cellular response to stress), GO:0031669 (cellular response to nutrient levels), GO:0009267 (cellular response to starvation), GO:0031667 (response to nutrient levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Potassium uptake protein TrkA, putative (Q72F06)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Function: Not known
InterPro domains:
- IPR003148: Regulator of K+ conductance, N-terminal lobe (domain) [5-123]
- IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [8-138]
- IPR050721: Trk/Ktr/HKT Potassium Transport (family) [8-217]
- IPR006037: Regulator of K+ conductance, C-terminal (domain) [138-221]
- IPR036721: Regulator of K+ conductance, C-terminal domain superfamily (homologous_superfamily) [134-221]
Sequence:
MATPKLEIGVIGLGKFGLQVSRTLVELGHSVVGIDSTEGRIRQAQDILSQVYQGNAADPAVLQQLRFQDLDCVIVSVGNSMETSLLVTLNLQEIGVRKIWVKAVSTEHKKVLTRLGVDHVILPEHDVATHLAHRLVNPGMLDLLPLGGGGQILLQELTVDKWAGRTLLDLRLANEHGVMVVAVKPAAFREYRFVPAAHEVLQQGDKLVVIGRHEDVLRLEP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0043933 (protein-containing complex organization), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly), GO:0051259 (protein complex oligomerization), GO:0051262 (protein tetramerization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Cathepsin L-like proteinase (EC 3.4.22.-) (Q24940)
Organism: Fasciola hepatica (Liver fluke)
Function: Thiol protease. Probably involved in interaction with host tissues. Displays a similar activity to that of papain. Has high activity on Z-Phe-Arg-NHMec, but no activity on Z-Arg-NHMec.
Subcellular location: Secreted {ECO:0000269|PubMed:8192668}.
InterPro domains:
- IPR013128: Peptidase C1A (family) [20-314]
- IPR025661: Cysteine peptidase, asparagine active site (active_site) [284-303]
- IPR000169: Cysteine peptidase, cysteine active site (active_site) [126-137]
- IPR039417: Papain-like cysteine endopeptidase (domain) [109-320]
- IPR000668: Peptidase C1A, papain C-terminal (domain) [108-321]
- IPR038765: Papain-like cysteine peptidase superfamily (homologous_superfamily) [19-321]
- IPR025660: Cysteine peptidase, histidine active site (active_site) [267-277]
- IPR013201: Cathepsin propeptide inhibitor domain (I29) (domain) [21-80]
Sequence:
MRLFILAVLTVGVLGSNDDLWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEEFKAKYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMVARFP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008234 (cysteine-type peptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0032963 (collagen metabolic process), GO:0009056 (catabolic process), GO:0030574 (collagen catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: UPF0208 membrane protein YfbV (P0A8D9)
Organism: Escherichia coli (strain K12)
Function: Not known
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
InterPro domains:
- IPR007334: Uncharacterised protein family UPF0208 (family) [9-151]
Sequence:
MSTPDNRSVNFFSLFRRGQHYSKTWPLEKRLAPVFVENRVIKMTRYAIRFMPPIAVFTLCWQIALGGQLGPAVATALFALSLPMQGLWWLGKRSVTPLPPAILNWFYEVRGKLQESGQVLAPVEGKPDYQALADTLKRAFKQLDKTFLDDL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016830 (carbon-carbon lyase activity), GO:0016831 (carboxy-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0060255 (regulation of macromolecule metabolic process), GO:0016043 (cellular component organization), GO:0010468 (regulation of gene expression), GO:0040029 (epigenetic regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: High-affinity nitrate transporter-activating protein 2.1 (OsNAR2.1) (Q6ZI50)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Acts as a dual component transporter with NTR2.1, NRT2.2 and NRT2.3. Required for high-affinity nitrate transport. Involved in the regulation of NRT2.1, NRT2.2 and NRT2.3 expression, and in both, HATS (high-affinity transport system) and LATS (low-affinity transport system) activities in plant roots. Imports nitrate with high affinity when expressed with NTR2.1, NTR2.2 or NTR2.3 in a heterologous system (Xenopus oocytes).
Subcellular location: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
InterPro domains:
- IPR016605: High-affinity nitrate transporter (family) [1-206]
Sequence:
MARLAGVAALSLVLVLLGAGVPRPAAAAAAKTQVFLSKLPKALVVGVSPKHGEVVHAGENTVTVTWSLNTSEPAGADAAFKSVKVKLCYAPASRTDRGWRKASDDLHKDKACQFKVTVQPYAAGAGRFDYVVARDIPTASYFVRAYAVDASGTEVAYGQSSPDAAFDVAGITGIHASLKVAAGVFSTFSIAALAFFFVVEKRKKDK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015103 (inorganic anion transmembrane transporter activity), GO:0015112 (nitrate transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0051234 (establishment of localization), GO:0006950 (response to stress), GO:0055085 (transmembrane transport), GO:0042221 (response to chemical), GO:1901700 (response to oxygen-containing compound), GO:0010035 (response to inorganic substance), GO:0009611 (response to wounding), GO:1901698 (response to nitrogen compound), GO:0098660 (inorganic ion transmembrane transport), GO:0006810 (transport), GO:1902074 (response to salt), GO:0010167 (response to nitrate), GO:0071705 (nitrogen compound transport), GO:0098661 (inorganic anion transmembrane transport), GO:0015698 (inorganic anion transport), GO:1902025 (nitrate import), GO:0015706 (nitrate transmembrane transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Jasmonoyl--L-amino acid synthetase GH3.3 (EC 6.3.2.52) (Auxin-responsive GH3-like protein 3) (OsGH3-3) (Indole-3-acetic acid-amido synthetase GH3.3) (Jasmonate-amino acid synthetase JAR2) (Jasmonic acid-amido synthetase JAR2) (Protein JASMONATE RESISTANT 2) (OsJAR2) (Q5NAZ7)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Catalyzes the synthesis of jasmonate-amino acid conjugates by adenylation. Catalyzes the conjugation of jasmonate (JA) to Ile when expressed in a heterologous system (E.Coli). Catalyzes in vitro the conjugation of jasmonate (JA) to Ile, Phe, Leu, Met, Val and Trp. May catalyze the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin (By similarity).
InterPro domains:
- IPR055377: GH3, middle domain (domain) [358-410]
- IPR004993: GH3 family (family) [17-424]
Sequence:
MLEKKATRSTRVDGVSGEAVIEEFERVTRDAANVQRETLRRILAENGGVEYLRGLGLAGATDPATFRARVPLATHADLEPYIDRIADGDASPVLTAKPATSISLSSGTTQGKRKYLLFNEELVKSTMQIYRISYAFRNREFPVENGKALQFIYSSRETRTKGGLTATTATTNVYRSEEFKATMRDIQSQCCSPDEVIFGPDFAQSLYCHLLAGLLAAGDVQIVSATFAHSVVLAFQTFERAWEDLCADIRRGEVSPSRVTSPAVRRAMAALLAAPNPGLADEVARKCAALSNWYGVIPALWPNARYVYGIMTGSMEHYVKKLRHYAGGLPLVAAEYGASEGWVGANVEPGTPPERATFTVLPDIAYFEFIPLKPVAGDGGYAEAEPVGLTEVAAGELYEVVMTTFAGNTRSSSSCMTLVAYYYLQSKKWMNICRFCISVHETSRNLVTCTFAATGHIMFAQK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0036094 (small molecule binding), GO:0016874 (ligase activity), GO:1901363 (heterocyclic compound binding), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0097367 (carbohydrate derivative binding), GO:1901265 (nucleoside phosphate binding), GO:0043168 (anion binding), GO:0000166 (nucleotide binding), GO:0043169 (cation binding), GO:0032553 (ribonucleotide binding), GO:0016879 (ligase activity, forming carbon-nitrogen bonds), GO:0016881 (acid-amino acid ligase activity), GO:0016208 (AMP binding), GO:0032555 (purine ribonucleotide binding), GO:0017076 (purine nucleotide binding), GO:0032559 (adenyl ribonucleotide binding), GO:0030554 (adenyl nucleotide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0009719 (response to endogenous stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0009314 (response to radiation), GO:0009416 (response to light stimulus), GO:0009733 (response to auxin)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Probable rRNA-processing protein EBP2 homolog (Q09958)
Organism: Caenorhabditis elegans
Function: Required for the processing of the 27S pre-rRNA.
Subcellular location: Nucleus, nucleolus {ECO:0000250}.
InterPro domains:
- IPR008610: Eukaryotic rRNA processing (family) [18-339]
Sequence:
MVRKMNKLAKRLASTSKSRQPEPESDSDGSEFDFDNAIEEKPMEAMDIEEVESDGDDDERELQAAFAAGLLKDGLNIQVAKKRPIINKSAEMKEKLAEITKDLPWVETLEVVTPHSEMDKKVENDDFQRELNFYKQAEKAVQIAYPRLLNLGIKVLRPTDYYAEMAKSDTHMQKVRKRLLGIQEMKERQEAFRRIREEKKFAVKVQKEVLAAKNTEKKNLAEAVKKHKKGMKQQLEDMLNNVKRHGLDQDDDAPTGAFGDRLGGRGGAGRGGAGRGGSMRNAGELKRKLKSDKFGYGGKKKGMKRNNKESFNDLFGAPRGGFGGRGRGGGRGGRGGRGRR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0009987 (cellular process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0050793 (regulation of developmental process), GO:0023051 (regulation of signaling), GO:0071840 (cellular component organization or biogenesis), GO:0051239 (regulation of multicellular organismal process), GO:0051093 (negative regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0050794 (regulation of cellular process), GO:0016043 (cellular component organization), GO:0048580 (regulation of post-embryonic development), GO:2000026 (regulation of multicellular organismal development), GO:0044085 (cellular component biogenesis), GO:0010646 (regulation of cell communication), GO:0048581 (negative regulation of post-embryonic development), GO:0061062 (regulation of nematode larval development), GO:0030030 (cell projection organization), GO:0006996 (organelle organization), GO:1902531 (regulation of intracellular signal transduction), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0044782 (cilium organization), GO:0060271 (cilium assembly), GO:0120031 (plasma membrane bounded cell projection assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005634 (nucleus)
Protein: UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) (Enoylpyruvate transferase) (UDP-N-acetylglucosamine enolpyruvyl transferase) (EPT) (Q4QLK7)
Organism: Haemophilus influenzae (strain 86-028NP)
Function: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00111}.
InterPro domains:
- IPR013792: RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta (homologous_superfamily) [1-419]
- IPR001986: Enolpyruvate transferase domain (domain) [7-408]
- IPR005750: UDP-N-acetylglucosamine 1-carboxyvinyltransferase (family) [1-418]
- IPR050068: UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA subfamily (family) [2-419]
- IPR036968: Enolpyruvate transferase domain superfamily (homologous_superfamily) [6-416]
Sequence:
MDKFRVYGQSRLSGSVNISGAKNAALPILFAAILATEPVKLTNVPELKDIETTLNILRQLGVIANRDETGAVLLDASNINHFTAPYELVKTMRASIWALAPLVARFHQAQVSLPGGCSIGARPVDLHISGLEKLGADIVLEEGYVKAQVSDRLVGTRIVIEKVSVGATLSIMMAATLAKGTTVIENAAREPEIVDTADFLNKMGAKITGAGSDHITTEGVERLTGCEHSIVPDRIETGTFLIAAAISGGRVVCQNTKADTLDAVIDKLREAGAQVDVTENSITLDMLGNRPKAVNIRTAPHPGFPTDMQAQFTLLNMVAEGTSIITETIFENRFMHIPELIRMGGKAEIEGNTAVCHGVEQLSGTEVIATDLRASISLVLAGCIATGETIVDRIYHIDRGYEHIEDKLRALGAKIERFSRSDEA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:0070887 (cellular response to chemical stimulus), GO:0046677 (response to antibiotic), GO:0071236 (cellular response to antibiotic)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: H(+)-exporting diphosphatase (EC 7.1.3.1) (Q8MTZ4)
Organism: Trypanosoma brucei
Function: Not known
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}.
InterPro domains:
- IPR004131: Pyrophosphate-energised proton pump (family) [13-826]
Sequence:
MIKMSPLLLKAAVVTACLCSLAVATTVEEQTAPKPIENATTYQQELGGRGKVDSPTAPGDAVSITSGIKVMSVTTATAIIFLASAFGFSFAMYWWYVASDIKITPGKGNIMRNAHLTDEVMRNVYVISKRVSDGANAFLFAEYRYMGIFMLGFGALLYFLLGVAMSSPQGEGKDGRPPVAVEAPWVNAAFSLYAFVIGAFTSVLAGWIGMRIAVYTNSRTAVMATVGSGGSDNDVLANGSQSRGYALAFQTAFRGGITMGFALTSIGLFALFCTVKLMQTYFGDSAERLPELFECVAAFGLGGSSVACFGRVGGGIYTKAADVGADLVGKVEKNIPEDDARNPGVIADCIGDNVGDIAGMGSDLFGSFGEATCAALVIAASSAELSADFTCMMYPLLITAGGIFVCIGTALLAATNSGVKWAEDIEPTLKHQLLVSTIGATVVLVFITAYSLPDAFTVGAVETTKWRAMVCVLCGLWSGLLIGYSTEYFTSNSYRPVQEIAESCETGAATNIIYGLSLGYISVLPPILAMAFTIYLSHHCAGLYGYALAALGILSTMSIALTIDAYGPISDNAGGIAEMAHMGHEIREITDALDAAGNTTAAIGKGFAIGSAAFVALALYGAYVSRVGISTVNLLDARVMAGLLLGAMLPYWFSALTMKSVGVAAMDMVNEIRRQFQDPAVAAGTKEPDYESCVNIATGAALQQMVAPACLVMLAPIVTGILFGRYTLAGLLPGALVSGVQVAISASNTGGAWDNAKKYIEKGGLRDKSKGKGSPQHAAAVIGDTVGDPLKDTSGPALNILVKLMAIISVVFAPVVQSKLGGLLVK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016462 (pyrophosphatase activity), GO:0004427 (inorganic diphosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0042592 (homeostatic process), GO:0048878 (chemical homeostasis), GO:0019725 (cellular homeostasis), GO:0006885 (regulation of pH), GO:0050801 (monoatomic ion homeostasis), GO:0055082 (intracellular chemical homeostasis), GO:0098771 (inorganic ion homeostasis), GO:0030641 (regulation of cellular pH), GO:0055080 (monoatomic cation homeostasis), GO:0006873 (intracellular monoatomic ion homeostasis), GO:0051453 (regulation of intracellular pH), GO:0055074 (calcium ion homeostasis), GO:0006874 (intracellular calcium ion homeostasis), GO:0051452 (intracellular pH reduction), GO:0030003 (intracellular monoatomic cation homeostasis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0020022 (acidocalcisome), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Aspartate-beta-hydroxylase (A0A8I5ZX27)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Sarcoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004157}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004157}.
InterPro domains:
- IPR039038: Aspartyl/asparaginyl beta-hydroxylase family (family) [1-188]
- IPR007943: Aspartyl beta-hydroxylase/Triadin domain (domain) [50-130]
Sequence:
MAPRKNAKGGGGNSSSSGSGSGSGSPSTGSSGSSSSPGARREAKHGGHKNGRRGGISGGSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLAKAKDFRYNLSEVLQGKLGVYDADGDGDFDVDDAKVLLGLTKDGSNENIDSLEEVLTILAEESSDWFYGFLSFLYDIMTPFEMLEEEEEEETADGVDGTSQKEGVQGKTCVILDLHNQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0042592 (homeostatic process), GO:0048878 (chemical homeostasis), GO:0019725 (cellular homeostasis), GO:0050801 (monoatomic ion homeostasis), GO:0055082 (intracellular chemical homeostasis), GO:0098771 (inorganic ion homeostasis), GO:0006873 (intracellular monoatomic ion homeostasis), GO:0055074 (calcium ion homeostasis), GO:0055080 (monoatomic cation homeostasis), GO:0006874 (intracellular calcium ion homeostasis), GO:0030003 (intracellular monoatomic cation homeostasis), GO:0051480 (regulation of cytosolic calcium ion concentration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: BcDNA.GH02384 (Q9Y168)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
InterPro domains:
- IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [39-420]
- IPR003386: Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase (family) [80-405]
Sequence:
MRLKSGVLSLLLLTTFLALGECFWPFSKWHGRNDNPSAPPEPKLSPVIFVPGDGGSQMDARLNKPNSPYLICQKTHDWYNLWLDLEQLVIPIVYCWIDNVKLYYDKVTRTTHNTPGVETRIPGWGNPEVVEWIDPTKNSAGAYFKDIANELVKLGYIRKQNIHGAPYDFRKAPNENQQFFIDLKQLVEDSYEANNQSAVTFISHSMGSLMTLVFLQEQTLQWKAKYVKRMISLAGVWAGSFKAVKVFAMGDDLDSFALSAKILKAEQITHPSTAWLLPSPLFWKPTEVLAMTPSRNYTMAQLEEFFKDLDYMTGWEMRKDTIRYNRNFDPPNVELHCLYGEGIDTVERLQYKKSDISGETPKLIMGLGDGTVNQRSLRACKYWAGYSKAPINTLALQNVDHLHILSNPDVLKYIRTVMQQP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0017171 (serine hydrolase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0006629 (lipid metabolic process), GO:0006638 (neutral lipid metabolic process), GO:0046486 (glycerolipid metabolic process), GO:0006639 (acylglycerol metabolic process), GO:0006641 (triglyceride metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0005773 (vacuole), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0005764 (lysosome)