lokahq/bioreason-rl huggingface dataset:
Protein: Ribosomal lysine N-methyltransferase 5 (EC 2.1.1.-) (Q12367)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates 60S ribosomal protein L1 (RPL1A and RPL1B) at 'Lys-46'.
InterPro domains:
- IPR029063: S-adenosyl-L-methionine-dependent methyltransferase superfamily (homologous_superfamily) [72-365]
- IPR019410: Lysine methyltransferase (family) [62-340]
Sequence:
MAFKLWLLDEETIYEHVFERYTQLEGQSGKLAQDLGIQDRRGGVLEITFEPSGLEGGRKKKRVRRRNKASSVEEDQNVAVDSYHVSVGQSISSLRSSRDNGNSTTGYVLWSTTPFFINWLLYSTSAAPFRLGSQVEVTCGSSCEGHKLELPRLVDLTGADRGKRGILELGAGISGILPVILGNFVDTYVSTDQKGILNKLKDNIMENLSQLTRKRCISRSLRLELPTVEPVGDADITAASLPSKSTLHLEVAALDWEKINLQDKKTHSLHPELSLIGETCSSVYVIAMDVIYNEYLIDPFLKTLKQLKHWLQTTYNLQFHVLVGIHLRSQEVTTLFLEKAIIEYDFTVYDIVDQVIQESRFNFYLIT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016741 (transferase activity, transferring one-carbon groups), GO:0008276 (protein methyltransferase activity), GO:0016279 (protein-lysine N-methyltransferase activity), GO:0008168 (methyltransferase activity), GO:0008757 (S-adenosylmethionine-dependent methyltransferase activity), GO:0008170 (N-methyltransferase activity), GO:0016278 (lysine N-methyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0032259 (methylation), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043414 (macromolecule methylation), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0006479 (protein methylation), GO:0008213 (protein alkylation), GO:0018022 (peptidyl-lysine methylation), GO:0018193 (peptidyl-amino acid modification), GO:0018205 (peptidyl-lysine modification), GO:0018023 (peptidyl-lysine trimethylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Insulin-like growth factor 2 (Insulin-like growth factor II) (Q8JIE4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU000406}.
InterPro domains:
- IPR016179: Insulin-like (domain) [51-108]
- IPR013576: Insulin-like growth factor II E-peptide, C-terminal (domain) [144-199]
- IPR036438: Insulin-like superfamily (homologous_superfamily) [38-116]
- IPR022334: Insulin-like growth factor II (family) [73-161]
- IPR022353: Insulin, conserved site (conserved_site) [94-108]
- IPR022352: Insulin/IGF/relaxin (family) [52-108]
- IPR022350: Insulin-like growth factor IGF-1/2 (family) [55-119]
Sequence:
MEDQLKHHSVCHTCSRTDSFVNKVIKMFWSIRMPICILFLTLSAFEVASAETLCGGELVDALQFVCEDRGFYFSRPTSRSNSRRSQNRGIVEECCFSSCNLALLEQYCAKPAKSERDVSATSLQVIPVMPALKQEVPRKHVTVKYSKYDVWQRKAAQRLRRGIPAILRAKKFRRQAERIKAQEQLLHHRPLITLPSKLPPILLPTENYVSHK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0005159 (insulin-like growth factor receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0007389 (pattern specification process), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0009790 (embryo development), GO:0001756 (somitogenesis), GO:0009888 (tissue development), GO:0003002 (regionalization), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0035239 (tube morphogenesis), GO:0035282 (segmentation), GO:0048568 (embryonic organ development), GO:0061053 (somite development), GO:0060429 (epithelium development), GO:0048514 (blood vessel morphogenesis), GO:0002040 (sprouting angiogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development), GO:0009952 (anterior/posterior pattern specification), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development), GO:0030903 (notochord development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Uncharacterized protein YggR (P52052)
Organism: Escherichia coli (strain K12)
Function: Not known
InterPro domains:
- IPR006321: Pilus retraction protein PilT/PilU (family) [2-325]
- IPR003593: AAA+ ATPase domain (domain) [119-271]
- IPR001482: Type II/IV secretion system domain (domain) [63-265]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [4-326]
- IPR050921: Type IV secretion system, general secretion pathway E ATPase (family) [2-298]
Sequence:
MNMEEIVALSVKHNVSDLHLCSAWPARWRIRGRMEAAPFDTPDVEELLREWLDDDQRAILLENGQLDFAVSLAENQRLRGSAFAQRHGISLALRLLPSHCPQLEQLGAPTVLPELLKSENGLILVTGATGSGKSTTLAAMVGYLNQHADAHILTLEDPVEYLYASQRCLIQQREIGLHCMTFASGLRAALREDPDVILLGELRDSETIRLALTAAETGHLVLATLHTRGAAQAVERLVDSFPAQEKDPVRNQLAGSLRAVLSQKLEVDKQEGRVALFELLINTPAVGNLIREGKTHQLPHVIQTGQQVGMITFQQSYQHRVGEGRL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0016887 (ATP hydrolysis activity), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016462 (pyrophosphatase activity), GO:0017111 (ribonucleoside triphosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0048870 (cell motility), GO:0001539 (cilium or flagellum-dependent cell motility), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0022607 (cellular component assembly), GO:0097588 (archaeal or bacterial-type flagellum-dependent cell motility), GO:0030030 (cell projection organization), GO:0006996 (organelle organization), GO:0070925 (organelle assembly), GO:0030031 (cell projection assembly), GO:0044781 (bacterial-type flagellum organization), GO:0071973 (bacterial-type flagellum-dependent cell motility), GO:0044780 (bacterial-type flagellum assembly), GO:0140694 (non-membrane-bounded organelle assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2 (Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 2) (T-cell lymphoma breakpoint-associated target protein 1) (Q4PNJ2)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
InterPro domains:
- IPR008516: Na,K-Atpase Interacting protein (family) [1-207]
Sequence:
MGYCSGRCTLIFICGMQLVCVLERQIFDFLGYQWAPILANFVHIIIVILGLFGTIQYRPRYVTGYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCMVTSVTPAPDWAPEDHRYITVSGCFLDYQYIEVAHSSLQIVLALAGFIYACYVVRCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYMSK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0000902 (cell morphogenesis), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0022008 (neurogenesis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0007399 (nervous system development), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0021953 (central nervous system neuron differentiation), GO:0048699 (generation of neurons)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: 4,5-DOPA dioxygenase extradiol (MjDOD) (EC 1.13.11.29) (DOPA 4,5-dioxygenase) (B6F0W8)
Organism: Mirabilis jalapa (Garden four-o'clock)
Function: Opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid. Produces mainly (S)-betalamic acid. Required for the coloration of flowers.
Subcellular location: Cytoplasm {ECO:0000305}.
InterPro domains:
- IPR004183: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B (domain) [5-256]
- IPR014436: Extradiol aromatic ring-opening dioxygenase, DODA-type (family) [1-261]
Sequence:
MKGTYYINHGDPLMYLKKHIKLRQFLEGWQENVVIEKPKSILIISAHWDTNVPTVNFVEHCDTIHDFDDYPDPLYQIQYRAPGAPNLAKKVEELLKESGMECEIDTKRGLDHAAWFPLMFMYPEANIPICELSVQPSKDGIHHYNVGKALSPLLQQGVLIIGSGGTVHPSDDTPHCPNGVAPWAIEFDNWLEDALLSGRYEDVNNFKKLAPNWEISHPGQEHLYPLHVALGAAGKNPKTQLIHRSWAANGVFGYSTYNFTPTTQKTD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0051213 (dioxygenase activity), GO:0016701 (oxidoreductase activity, acting on single donors with incorporation of molecular oxygen), GO:0016702 (oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006725 (cellular aromatic compound metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Probable acetyl-CoA acetyltransferase (EC 2.3.1.9) (Acetoacetyl-CoA thiolase) (Q86AD9)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Not known
InterPro domains:
- IPR020616: Thiolase, N-terminal (domain) [26-284]
- IPR002155: Thiolase (family) [20-414]
- IPR020613: Thiolase, conserved site (conserved_site) [360-376]
- IPR020617: Thiolase, C-terminal (domain) [291-413]
- IPR016039: Thiolase-like (homologous_superfamily) [16-414]
- IPR020615: Thiolase, acyl-enzyme intermediate active site (active_site) [106-124]
Sequence:
MISNLSKVLNSNVKRMYTTAKNLESVVIVSAVRTPIGSIGGSLSTIPGTKLSSITIEEAVKRAGIKPSDVDEAIIGNVISANLGQAPARQCALGAGLEQKTITTTINKVCSSGMKAIVFGAQSIALGHSKTVVAGGFESMSQVPYYADKMRFGAKYGNQTFIDGLVRDGLADAYNGSAMGVCGDDCADKYKITREQQDKFAVDSYLRALEAQKNGFFNDEIVQVPIVGRGGKVTYVVEDEEPKKVLFDKIPNLKPAFTPNGTVTPANASKLNDGASSVILMSESHAKELGLKPLARIIGYADAEQAPIEFPTAPALAIPKALKNAGINMSQVDLFEINEAFAVVGLANAKILDIDHNKLNVNGGAVALGHPIGSSGCRIVVTLTHLLQNKNLKYGVAAICNGGGGSTALVLEKL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016408 (C-acyltransferase activity), GO:0016407 (acetyltransferase activity), GO:0003988 (acetyl-CoA C-acyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0051703 (biological process involved in intraspecies interaction between organisms), GO:0099120 (socially cooperative development), GO:0048856 (anatomical structure development), GO:0030587 (sorocarp development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0030139 (endocytic vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle), GO:0045335 (phagocytic vesicle)
Protein: Transducin/WD40 repeat-like superfamily protein (F4HUT3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
InterPro domains:
- IPR001680: WD40 repeat (repeat) [33-428]
- IPR019775: WD40 repeat, conserved site (conserved_site) [206-341]
- IPR020472: PAC1/LIS1-like, WD-40 repeat (repeat) [119-341]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [1-437]
- IPR042238: DNA excision repair protein Rad28/ERCC8/Ckn1/ATCSA-1 (family) [1-451]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [39-429]
Sequence:
MWEAIKDRETGRIRSNSFANRFKSRRILSLQLSNRKDFVSPHRGSVNSLQVDLTEGRYLLSGAADGSAAVFDVQRATDYEASGLIAKHKCIFTVDKQHENGHKYAISSAIWYPIDTGLFITGSFDHYLKVWDTNTAQAVVDFKMPGKVYRTAMSSMAMSHTLIAAGTEDVQVRLCDIASGAFSHTLSGHRDGVMSVEWSTSSEWVLYTGGCDGAIRFWDIRRAGCFRVLDQSQTQLGFRPPILKRTAVGSKLSSVAKSSLGGQNRLKTLQSKQTGSQSVKGSSSAKASVEKSRQKRIHPGMLSTLDRATAHYGAVTGLKATNDGMYLLSAGSDSRIRLWDIESGRNTLVNFETGRIQTNKGIQLDTSDDPALVFVPCMKTVKVAFGMWSGRTTLMLRGHYESVNTCCFNSNDQELYTSGSDRQILVWSPGGTVEDEMVQDEVAEDKDNWSD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0044237 (cellular metabolic process), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0009314 (response to radiation), GO:0033554 (cellular response to stress), GO:0006259 (DNA metabolic process), GO:0009416 (response to light stimulus), GO:0090304 (nucleic acid metabolic process), GO:0006974 (cellular response to DNA damage stimulus), GO:0006281 (DNA repair), GO:0009411 (response to UV), GO:0010224 (response to UV-B)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Carboxyl-terminal protease (EC 3.4.21.-) (Q729L4)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Function: Not known
InterPro domains:
- IPR036034: PDZ superfamily (homologous_superfamily) [82-181]
- IPR055210: Activating protease CtpA/B, N-terminal domain (domain) [28-78]
- IPR004447: C-terminal-processing peptidase S41A (family) [31-359]
- IPR029045: ClpP/crotonase-like domain superfamily (homologous_superfamily) [32-361]
- IPR005151: Tail specific protease (domain) [167-357]
- IPR041489: PDZ domain 6 (domain) [109-161]
- IPR001478: PDZ domain (domain) [82-165]
Sequence:
MRVTLWVVSLGLCAAVAFSGGAVFATTEESKYDALKRFSQVLDIVERYYVRDVPRKDLMNGAVKGMLQGLDPHSTFLSPEEFKEMQETTSGEFFGIGIEISSENGQLTVVSPIEDTPAFKAGLKAGDLILAVDGQPTQEMSTQEAVSRIRGPKGSEVELLILHREAKAPSTVKIVRDAIPLVSVKSKQLEQGYVWVRLTRFSERTTSDLLEALREANKRGPVKGVVLDLRNNPGGLLDQAVSVSDVFLRDGGIVSIRGRGDDTGREYNAKAQSTDVTAPMVVLINAGSASASEIVAGALRDQKRALLVGERSFGKGSVQNVIPLSDGAGLKLTVALYYTPNGRSIQAEGIDPDIEIPFEAPREDDAKPMQRFNMLREKDLSRHLENGAGGKQGKNDQSDEVRDLLERDNQLRMALQFVKRLPALKEIR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0030030 (cell projection organization), GO:0022607 (cellular component assembly), GO:0030031 (cell projection assembly), GO:0043711 (pilus organization), GO:0009297 (pilus assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0031975 (envelope), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030312 (external encapsulating structure), GO:0009279 (cell outer membrane), GO:0019867 (outer membrane), GO:0030313 (cell envelope)
Protein: Nucleobindin 1 (Q9VVK7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
InterPro domains:
- IPR040250: Nucleobindin (family) [5-504]
- IPR011330: Glycoside hydrolase/deacetylase, beta/alpha-barrel (homologous_superfamily) [306-383]
- IPR011992: EF-hand domain pair (homologous_superfamily) [224-314]
- IPR057576: NUCB1-like, N-terminal domain (domain) [19-156]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [300-312]
Sequence:
MVQNVALLGLALIAISASIVALPVTQNKKDHKEAAESSTPATADVETALEYERYLREVVEALEADPEFRKKLDKAPEADIRSGKIAQELDYVNHHVRTKLDEIKRREVERLRELANQAYELSNDIDRKHLKVSQHLDHDNEHTFEIEDLRKLIQKTSDDLAEADRKRRGEFKEYEMQKEFEREAQKKEMDEESRKKFETELKEKEEKHKDHEKLHHPGNKAQLEDVWEKQDHMDKNDFDPKTFFSIHDVDSNGYWDEAEVKALFVKELDKVYQSDLPEDDMRERAEEMERMREHYFQETDMNHDGLISIDEFMVQTNKEEFQKDPEWETIDRQQQYTHEEYLEYERRRQEEVQRLIAQGQLPPHPNMPQGYYAAPPPGGVAYQQAPPGAQLHYQHPDQVHAQQQQQYAQQQQQYAQQYQQQQYGNGQQPVQLQPNQVYQHAGQIPQQQQPVYQNQPVYQQQQPVYQQQQPVQQQQKPVQQPVQQQQQPVQQQQQPVQQQQQTVQQQQPVQQQQQTVQQQQPVQQQQQTAQQQPVAQQQIHNQSPPPVLNQQVPVQQQQKQHQESLNQQH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0005509 (calcium ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0000003 (reproduction), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0019953 (sexual reproduction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0042742 (defense response to bacterium), GO:0050829 (defense response to Gram-negative bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005576 (extracellular region), GO:0005615 (extracellular space), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Glycophorin-E (P15421)
Organism: Homo sapiens (Human)
Function: This protein is a minor sialoglycoprotein in human erythrocyte membranes.
Subcellular location: Membrane; Single-pass type I membrane protein.
InterPro domains:
- IPR001195: Glycophorin (family) [1-45]
Sequence:
MYGKIIFVLLLSGIVSISASSTTGVAMHTSTSSSVTKSYISSQTNGITLINWWAMARVIFEVMLVVVGMIILISYCIR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007155 (cell adhesion), GO:0098609 (cell-cell adhesion), GO:0098742 (cell-cell adhesion via plasma-membrane adhesion molecules), GO:0007157 (heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Protein kinase, putative (Q387Y1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
InterPro domains:
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [441-1152]
- IPR017441: Protein kinase, ATP binding site (binding_site) [453-476]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [581-593]
- IPR000719: Protein kinase domain (domain) [447-1150]
Sequence:
MLLDFVLKYVRGTHPADSEDASKEGSPSAASAYGGKDRKHHPPAEGHRSPPDENVSGNEQGRGIMTLLPKVPSAESVRDKPFYSNGSGHGERRELDGHEKESSVDGKHRQHRSHVLPSMDMDRAPSQFSASGSRQLEGPHGVNCAQVTEQSLEVHDPNDGVDRCHDRSGTGTAHDNNRLAADQIGCTATVAEELRAHRSTTPIKIVNAAAQNVEDDIDDDNEVVGNALVKPMTPQSYSSLMFNSDFRKLNYKEDDIKRRIAVGEGRSLLILQNRGVSCDALSAIPALERHVSDARSCPARSVQSSECAGGVLTSSPRKEEPQRERNFHSEKRPPTADTDGQTICTCGLTVGSSPTEQFSCPGGAAEDSFNRKTCKIHGTNLGCRAHSSELISEWVSECIPPEPVELINVNAGRPRVNVLKKGVINCCVAVRKSLDDAKMMLNNKYVIYFRWCLGVGSSSKVFLCYNLHEKAFYAMKVYNRGRLRRKGFGANCALNNVRREIDIMKKLRHPNILSLVEVIDDPFSRKIYLVLELAEKGAVMTLEGDGTVVPSVSGAALPEEEVARAIRSVVEALIYVHDLGIVHRDVKPQNILLDAEECVKLSDFGVSIMVDGCTSPVPREGTVAFLPPEMLASSEVRVALSDAASHKDTSIGSTNSHQVCSRMNDELPVKTLPEGEREEIGSLQTTDTSVRTQNDNASVSVGSECKQVASTGVASLSGSNNPGCEVSPSDCAGLPACDPTGTPVADFFKADVFALGVTTFVLLMGRLPWLARSSRSQMKAINAQPDPFEEPLRKAYGCPSGEGLKGPTLCNRSLHGSEPPESSAIFLEGTTERTASQQMFSSSSCGRFLASNDADTLDHHVSRSSTKPDCTDWCNSGMSRVSREDEVGAQLLASSPTQCAIGGEWKDSKLLQSSEVGGSPRAHEEADGAQRSPYGHTNTSMRVCCGCRSSSNTATVPTTSFGSLSEAGKAPVSRENKPEFSAVSCFSQPNAAGEATPFRRTHSPSKFPLGRRSTSVFVSNNSSLHSWRIQEGHQPHAGDAVLNEDLEGSLTSDANFPLSAGREFTFPLCQHCATCNNTNNGPYTESGVGDTMSGEQTSGSKMEVPERRGLPETDTHKCISADAIEFVRSCLRINPMERSTMKELYEMPWLQKGR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010468 (regulation of gene expression), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)