lokahq/bioreason-rl huggingface dataset:
Protein: Anion transporter ABTS-2 (Bicarbonate transporter-like transmembrane domain-containing protein) (G5EGB9)
Organism: Caenorhabditis elegans
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
InterPro domains:
- IPR016152: Phosphotransferase/anion transporter (homologous_superfamily) [20-198]
- IPR003020: Bicarbonate transporter, eukaryotic (family) [102-736]
- IPR011531: Bicarbonate transporter-like, transmembrane domain (domain) [229-736]
Sequence:
MPELLCRTERVEHARNFKTEVRGLMDVDHLIERACIHRNMNHSHIHTILLSLFSDLSSRFPQEKFDLALFKNAVFSVSDRDSRAPRLHHKLQSYSGTDFFDVNQTWIVTYAQLDGLKQSHMALATLEDATNLGLEMEEARTVVLILSPSYEKHTKSAAEIARTFATLLMNDTLRQSVNDAADDDQLRDLLTEYAKGLSQQLTIQVNGKPIADDDDEYESKNSSFCPYYPFRGLVKDFKRRMANYKSDYLDGIKDRRSVSKVISTAVFLIFTILPTSIAYGMLNENNTNGAINVQKVVLGQWIGSLLFGIFGGQQLLILSTTAPLSIYIAVIYQVAQTNDWDFFQMYASVGIYAMGLLILASVFQLASLMKFTTRSTEEIFSVFIALALIIKAIMAIVHVYTHGYLGCINNVAGDLCDPAEPLLFIFLLFGTTWLSMTIISFRSSPYLSRWKRDLVSDYALPIAVLVFSFISFFGFSDVKKEQFQIFSRETDAFFVPFFNLPAEAQLPAVGLAIPLSILFFMDQLLVTNTVDNKDNKLKKGSAHHWDLLVVGVLNIGLSIFGLPWMHGALPSAYLHLKALSDVEDRLHNGYIQTVIVHVRETRLATLIAHIIMIPIYFFLVPHITVFIPTSIFNGVFLFMAFSSLTGNEFWERILLIFTEQRAYPPTHYIRRVPQRVVHQFTIIEFIQLVILVAIGFAQYHYVEMVFPIVIAAFIPFRHFFLPLFIRKQYLEAIDGQH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015267 (channel activity), GO:0005372 (water transmembrane transporter activity), GO:0015250 (water channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0098660 (inorganic ion transmembrane transport), GO:0006810 (transport), GO:0034220 (monoatomic ion transmembrane transport), GO:0098656 (monoatomic anion transmembrane transport), GO:0098661 (inorganic anion transmembrane transport), GO:0006811 (monoatomic ion transport), GO:0015698 (inorganic anion transport), GO:0006821 (chloride transport), GO:0006820 (monoatomic anion transport), GO:1902476 (chloride transmembrane transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0045178 (basal part of cell), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0009925 (basal plasma membrane), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0016323 (basolateral plasma membrane)
Protein: Sad1 and UNC84 domain containing 1 (A0A8I6ALL7)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Nucleus inner membrane {ECO:0000256|ARBA:ARBA00004540}.
InterPro domains:
- IPR032680: SUN domain-containing protein 1, N-terminal (domain) [66-380]
- IPR045119: SUN domain-containing protein 1-5 (family) [48-876]
- IPR012919: SUN domain (domain) [716-877]
- IPR040994: SUN coiled coil domain 2 (domain) [641-699]
Sequence:
MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHRLEPVFDSPRMSRRSLRLITTTAAYSSGDGQTVDTHISTSRATPAKGRETRTVKQRSASKPAFSINHLSGKGLSSSTSHDSSCSLRSATVLRHPVLDESLIREQTKVDHFWGLDDDGDLKGGNKAATQGNGELAAEVASSNGYTCRDCRMLSARTDALTAHSAVHGPTSRVYSRDRTLRPRGASFYLDRTLWLAKYTSSSFASFIVQLFQVVLMKLNFESETYKLKGYESRAYESQSYETKSHESEAHLGHCGRMTAGELSRVDGESLCDLLVRALRRTRAAGWSVAEAMWSVLWLAVTAPGKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGFSLWGQGNFFSLLPMLNWTAMQPAQRVDNPKDMHRPGPLSPSPPLKVDPMASQWPQESDMGQKIASLSAQCHNHDERLAELTVLLQKLQIRVDQVDDGREGLSLWVKDMVGQHLQEIGSIEPPDAKTDFLTLHHDHEVRLSSLEDVLRKLTEKSEAIQKELEETKLRAGSRDEEQPLLDRVQHLELELNLLKSQLSDWQHLRSSCEQADARIQETVQLMFSEDQPGGSLEWLLQKLSSRFVSKDELQVLLHDLELKLLQNITHHITVTGQAPTSEAIVSAMSQAGISGITEAQAHIIVNNALRLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGVPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPRDFAVYGLETEYQEEGQPLGRFTYDQEGDSLQMFHTLERPDQGFQIVELRVLSNWGHPEYTCLYRFRVHGEPIQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005521 (lamin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0001503 (ossification), GO:0009612 (response to mechanical stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: RNA helicase (EC 3.6.4.13) (Q68FX3)
Organism: Rattus norvegicus (Rat)
Function: Not known
InterPro domains:
- IPR014014: RNA helicase, DEAD-box type, Q motif (domain) [91-119]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [88-478]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [110-309]
- IPR011545: DEAD/DEAH-box helicase domain (domain) [116-279]
- IPR001650: Helicase, C-terminal domain-like (domain) [305-473]
Sequence:
MATDSWALAVDEQEAAVKSMNSLQIKEEKVKADTNGVIKTSTTAEKTEEEEKEDRAAQSLLNKLIRSNLVDNTNQVEVLQRDPSSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPMMLAEPPQNLIAQSQSGTGKTAAFVLAMLSRVEPADRHPQCLCLSPTYELALQTGKVIEQMGKFHPELKLAYAVRGNKLERGQKVGEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNIIKLKREEETLDTIKQYYVLCNNREEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0016887 (ATP hydrolysis activity), GO:0004386 (helicase activity), GO:1901363 (heterocyclic compound binding), GO:0016787 (hydrolase activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0097159 (organic cyclic compound binding), GO:0008186 (ATP-dependent activity, acting on RNA), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0140098 (catalytic activity, acting on RNA), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0003724 (RNA helicase activity), GO:0003723 (RNA binding), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016462 (pyrophosphatase activity), GO:0017111 (ribonucleoside triphosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0042221 (response to chemical), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0010942 (positive regulation of cell death), GO:0010035 (response to inorganic substance), GO:0010941 (regulation of cell death), GO:0010038 (response to metal ion), GO:0043067 (regulation of programmed cell death), GO:0043068 (positive regulation of programmed cell death), GO:0043065 (positive regulation of apoptotic process), GO:0042981 (regulation of apoptotic process), GO:0010043 (response to zinc ion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)
Protein: Uroporphyrinogen decarboxylase (EC 4.1.1.37) (C6KSS1)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Not known
InterPro domains:
- IPR038071: UROD/MetE-like superfamily (homologous_superfamily) [54-411]
- IPR006361: Uroporphyrinogen decarboxylase HemE (family) [75-409]
- IPR000257: Uroporphyrinogen decarboxylase (URO-D) (domain) [62-409]
Sequence:
MLKCLVTPLLICILTIKILCFINLKKLRFNIIKTETILNMNEVGEIYSRPENLKYEKFGRPQNDLILNVIENKNEEKKFKKIPLWIMRQAGRYLPEYVEIRKKYDFFEICKSPDLSSYVSIMPYDRFKTDMIVIFSDILIIFVAMGIDIKFVENLGPVFNLEIYNMNDFNKLNLNMKEIIDNLYYVYDSINLTKKKINNDVPILGFCGSPFTLFMYLTKNNKKTYEDSFKFLYEKPNDAHQIINKLSDICLNHLINQIDSGANIIQIFDSNAELVDKNIFNEFSIIYLKKVIEIIKKYRPNIYIILFIKNNFHDDIKNLKIDVLSITHKQLIDNTDQFYFKLFQNNIILQGALDPYILLLNDHELIQKHIIQMMKNITHKNKYIANLGHGILPTTKIKNVNLFIDTIRNNEWS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016830 (carbon-carbon lyase activity), GO:0016831 (carboxy-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0042440 (pigment metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0042168 (heme metabolic process), GO:0046483 (heterocycle metabolic process), GO:0046148 (pigment biosynthetic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0033013 (tetrapyrrole metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0018130 (heterocycle biosynthetic process), GO:0006783 (heme biosynthetic process), GO:0006778 (porphyrin-containing compound metabolic process), GO:0033014 (tetrapyrrole biosynthetic process), GO:0006779 (porphyrin-containing compound biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0020011 (apicoplast), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Matrix protein (Protein M) (Q9IK90)
Organism: Nipah virus
Function: Plays a crucial role in virion assembly and budding. Forms a shell at the inner face of the plasma membrane. Transits through the host nucleus before gaining the functional ability to localize and bud from the plasma membrane. Mediates together with fusion protein the incorporation of the glycoprotein to the viral particles. Participates also in the inhibition of the host interferon type I antiviral response by interacting with and thereby inhibiting host TRIM6.
Subcellular location: Virion. Host cytoplasm. Host cell membrane {ECO:0000269|PubMed:17005661, ECO:0000269|PubMed:19000317, ECO:0000269|PubMed:21085610}. Host nucleus {ECO:0000269|PubMed:21085610}. Note=During bud formation, associates at the inner side of the plasma membrane of infected cells. Nuclear-cytoplasmic trafficking is essential for budding and requires matrix ubiquitination. {ECO:0000269|PubMed:21085610}.
InterPro domains:
- IPR000982: Matrix protein, N-terminal domain (domain) [17-184]
- IPR042540: Viral matrix protein, N-terminal domain (homologous_superfamily) [32-191]
- IPR042539: Viral matrix protein, C-terminal domain (homologous_superfamily) [192-352]
- IPR055413: Matrix protein, C-terminal, Paramyxoviridae (domain) [187-345]
Sequence:
MEPDIKSISSESMEGVSDFSPSSWEHGGYLDKVEPEIDENGSMIPKYKIYTPGANERKYNNYMYLICYGFVEDVERTPETGKRKKIRTIAAYPLGVGKSASHPQDLLEELCSLKVTVRRTAGSTEKIVFGSSGPLNHLVPWKKVLTSGSIFNAVKVCRNVDQIQLDKHQALRIFFLSITKLNDSGIYMIPRTMLEFRRNNAIAFNLLVYLKIDADLSKMGIQGSLDKDGFKVASFMLHLGNFVRRAGKYYSVDYCRRKIDRMKLQFSLGSIGGLSLHIKINGVISKRLFAQMGFQKNLCFSLMDINPWLNRLTWNNSCEISRVAAVLQPSIPREFMIYDDVFIDNTGRILKG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0016032 (viral process), GO:0019080 (viral gene expression), GO:0019083 (viral transcription), GO:0039695 (DNA-templated viral transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0043657 (host cell), GO:0033643 (host cell part), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0033647 (host intracellular organelle), GO:0033648 (host intracellular membrane-bounded organelle), GO:0042025 (host cell nucleus)
Protein: NTF2 domain-containing protein (O18697)
Organism: Caenorhabditis elegans
Function: Not known
InterPro domains:
- IPR039908: Protein sepa-1 (family) [20-424]
Sequence:
MSFIAYPCAVPTQRQVPMSPPTTPRILMKLCPIMEIPIIGGPRQNGTYNVFIFDLKIRKFIPHRCSSCAVKILEDHLSPMYASGSVIFMRNEVTQEVEQYVYSFETGGFQQVDYPELVYSAEKFTESSFIVMIENSDGKKVLIERGGNEAVRKLEYRLGKCVEMPKVEVQLLAAEEFDDADPWSDNDSLSSEHLDYNETLPAFKTTFCQDFQMYVLYIITSRGHYEKYIYNQSTSQFEILDCEKCPDTTREVDLLPKYAEFCEEIQAYVIHVFNSFTDRMEQYVFDSKIQGFVEVNQPELKYDSSKDQDPTSSIFFVLKGTTVIMRGAQGRLKKEVYCSIKKHFVEVPNSVIKSFDTQFMEKKQKMDKKKKAKKIKKSKKKASKESQELDVLVEKIRLCDDPFSDGPSCSTSPDIPEDAPDDGMSILKQKFVESLTTLYGGSLPPYVQKELEQI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044237 (cellular metabolic process), GO:0061919 (process utilizing autophagic mechanism), GO:0009056 (catabolic process), GO:0016043 (cellular component organization), GO:0044248 (cellular catabolic process), GO:0006914 (autophagy), GO:0016236 (macroautophagy), GO:0000422 (autophagy of mitochondrion), GO:0006996 (organelle organization), GO:0022411 (cellular component disassembly), GO:0007005 (mitochondrion organization), GO:0000423 (mitophagy), GO:0061912 (selective autophagy), GO:1903008 (organelle disassembly), GO:0061726 (mitochondrion disassembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Lymphocyte antigen 6A-2/6E-1 (Ly-6A.2/Ly-6E.1) (Stem cell antigen 1) (SCA-1) (T-cell-activating protein) (TAP) (P05533)
Organism: Mus musculus (Mouse)
Function: T-cell activation.
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor.
InterPro domains:
- IPR045860: Snake toxin-like superfamily (homologous_superfamily) [24-107]
- IPR016054: Ly-6 antigen/uPA receptor-like (domain) [25-118]
- IPR051445: Lymphocyte Antigen 6 Family Modulators (family) [2-134]
- IPR018363: CD59 antigen, conserved site (conserved_site) [28-78]
Sequence:
MDTSHTTKSCLLILLVALLCAERAQGLECYQCYGVPFETSCPSITCPYPDGVCVTQEAAVIVDSQTRKVKNNLCLPICPPNIESMEILGTKVNVKTSCCQEDLCNVAVPNGGSTWTMAGVLLFSLSSVLLQTLL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0050792 (regulation of viral process), GO:0043903 (regulation of biological process involved in symbiotic interaction), GO:0048525 (negative regulation of viral process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007166 (cell surface receptor signaling pathway), GO:1903900 (regulation of viral life cycle), GO:0052372 (modulation by symbiont of entry into host), GO:1903901 (negative regulation of viral life cycle), GO:0046596 (regulation of viral entry into host cell), GO:0046597 (negative regulation of viral entry into host cell)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Variant surface glycoprotein (VSG)-related, putative (Q57YT2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
InterPro domains:
- IPR025932: Trypanosome variant surface glycoprotein, B-type, N-terminal domain (domain) [9-344]
Sequence:
MCGIKYCVVLFALVLRTSIFGEGKIVNEDEFGALCGMINFAKGALQRVEEAQEVNKSLTKIGSRCLELAGDVKLSNTCIDNNDESCEYSKVFWDAAKLSMSEGNAGKESLDDEKLEKVKQVASAAETIYGNMTKRHWVLNGDIIKQMLNRALYGIPHQPKKMRERSATRKRVCEGDVSQPEVNQGPVSLSRDLLCLCATDRKSRRKTKLCCENCVSGENRRVWRPRNDAQKRWNFLVSQCSNVEGHKEGFAKLVEKFRRSLNHRVDGCSGTMYVLGKHKKQLFWPLEFLSGYVPGPGVHYIINTRAGMVEDIPWLGELREIATLMGDLSEDNVEGRGLKSAIEKLEGDLEELFPTGGVRRG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0046812 (host cell surface binding), GO:0046789 (host cell surface receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response), GO:0042783 (evasion of host immune response), GO:0020033 (antigenic variation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: SD01032p (Q8T990)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
InterPro domains:
- IPR023339: CVC domain (domain) [343-394]
- IPR001356: Homeodomain (domain) [281-345]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [270-342]
- IPR017970: Homeobox, conserved site (conserved_site) [316-339]
- IPR052294: Visual system homeobox transcriptional regulators (family) [173-506]
Sequence:
MQATKMRTPFAIQEILGLGAYQQQATASATPSEAPPSPAAYLRGFLPPGFSTPHEFRGHFQQHFGAQFAEQAAARGQEYASSLANASGDEQSPSKNSSSSGNGGSGGSGSGSGGGNPTSNGLGHLGSPTASNGGSGGGAGVGGSGGGSGTSGSSSSTSGNGGNGGSSGSRSSPAGPHHSAALAAHQHAAAAAAAAHHHAAAAAAAHHAHHAHAQAHAHAHAHVHAHAAHAAHAAHAHAHHAEAFLGAAGGAGGNPNSLLAAHGGDVLVGPGGTGPGGKKKNKRRHGRTIFTSSQLEELEKAFKEAHYPDVSARELLSMKTGLAEDRIQVWYQNRRAKWRKTEKCWGHSTKMAEYGLYGAMVRHSLPLPETIIKSAKEDESVAPWLLGMHKKSLEAAELLKSDESDRETPTSDDTNTSYSAGSTHNSPISSFSISRLLFDAPPPAAGSAGGKGHHHHHHHHKGHHHAHVHAQAQAHAHMLLHHQQQQQQQQQQQQHHHHLHAAENSLQQQQVAGTGSGSGSGSGSGTGAGSTGPPAHHPYNQQQHLHHLQQLQQQQQQQQQQAQQQQQHHHHQHHHSVHHMHHHNAAAGYAEAAVAAAAAAAAVAAAANARNAAAAAAVAAASASASAAVTIAESEAEEEQDDIEDMELDKDCEVEEDVEPVDNDTNTNNEHDNECDADADVEADVDADADADPEIDICDDHDEEMRLQEQLLLKVKQEQAHLGSR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0048522 (positive regulation of cellular process), GO:0048856 (anatomical structure development), GO:0050794 (regulation of cellular process), GO:0008284 (positive regulation of cell population proliferation), GO:0042127 (regulation of cell population proliferation), GO:2000177 (regulation of neural precursor cell proliferation), GO:2000179 (positive regulation of neural precursor cell proliferation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Mbd3 protein (B2RZ64)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
InterPro domains:
- IPR032343: Methyl-CpG-binding domain protein 2/3, p55-binding region (domain) [101-170]
- IPR025884: Methyl-CpG binding protein 2/3, C-terminal domain (domain) [175-265]
- IPR016177: DNA-binding domain superfamily (homologous_superfamily) [51-118]
- IPR001739: Methyl-CpG DNA binding (domain) [18-98]
Sequence:
RPAGGGGPRDGTAAASGGGGEGNRAGDEPGGRDLQKRRRHRRRQARRRAESRGAMERKSPSGKKFRSKPQLARYLGGSMDLSTFDFRTGKMLMNKMNKSRQRVRYDSSNQVKGKPDLNTALPVRQTASIFKQPVTKITNHPSNKVKSDPQKAVDQPRQLFWEKKLSGLSAFDIAEELVRTMDLPKGLQGVGPGCTDETLLSAIASALHTSTLPITGQLSAAVEKNPGVWLNTAQPLCKAFMVTDDDIRKQEELVQQVRKRLEEALMADMLAHVEELARDGEAPLDKACAEEEEEEEEEEEEEPEPERV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0007568 (aging), GO:0009991 (response to extracellular stimulus), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0009790 (embryo development), GO:0031323 (regulation of cellular metabolic process), GO:1901700 (response to oxygen-containing compound), GO:0080090 (regulation of primary metabolic process), GO:0010033 (response to organic substance), GO:0007420 (brain development), GO:0048568 (embryonic organ development), GO:0007399 (nervous system development), GO:0032355 (response to estradiol), GO:0051052 (regulation of DNA metabolic process), GO:0033993 (response to lipid), GO:0031667 (response to nutrient levels), GO:0072359 (circulatory system development), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0007417 (central nervous system development), GO:0014070 (response to organic cyclic compound), GO:0007507 (heart development), GO:0044030 (regulation of DNA methylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0000785 (chromatin), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus), GO:0005694 (chromosome)