lokahq/bioreason-rl huggingface dataset:
Protein: Sterol O-acyltransferase 1 (EC 2.3.1.26) (Acyl-coenzyme A:cholesterol acyltransferase 1) (ACAT-1) (Cholesterol acyltransferase 1) (O70536)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol. Plays a role in lipoprotein assembly and dietary cholesterol absorption. Utilizes oleoyl-CoA ((9Z)-octadecenoyl-CoA) preferentially as susbstrateb a higher activity towards an acyl-CoA substrate with a double bond at the delta-9 position (9Z) than towards saturated acyl-CoA or an unsaturated acyl-CoA with a double bond at the delta-7 (7Z) or delta-11 (11Z) positions.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P35610}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P35610}.
InterPro domains:
- IPR014371: Sterol O-acyltransferase, ACAT/DAG/ARE types (family) [19-525]
- IPR030687: Sterol O-acyltransferase, metazoa (family) [1-543]
- IPR004299: Membrane bound O-acyl transferase, MBOAT (family) [167-515]
Sequence:
MVGEETSLRNRLSRSAENPEQDEAQKNLLDTHRNGHITMKQLIAKKRQLAAEAEELKPLFLKEVGCHFDDFVTNLIDKSASLDNGGCALTTFSILEEMKNNHRAKDLRAPPEQGKIFISRRSLLDELFEVDHIRTIYHMFIALLIIFILSTLVVDYIDEGRLVLEFSLLAYAFGQFPIVIWTWWAMFLSTLAIPYFLFQRWAHGYSKSSHPLIYSLIHGAFFLVFQLGILGFIPTYVVLAYTLPPASRFILILEQIRLVMKAHSYVRENVPRVLSAAKEKSSTVPVPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFLQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLMLFLSFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYVYKDLLWFFSKRFRPAAMLAVFALSAVVHEYALAVCLSYFYPVLFVLFMFFGMAFNFIVNDSRKRPVWNIMVRASLFLGHGVILCFYSQEWYARQRCPLKNPTFLDYVRPRTWTCRYVF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0008374 (O-acyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:0006629 (lipid metabolic process), GO:0006066 (alcohol metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0016125 (sterol metabolic process), GO:1902652 (secondary alcohol metabolic process), GO:0008202 (steroid metabolic process), GO:0008203 (cholesterol metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: LD22578p (Q8MZ45)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000256|ARBA:ARBA00004120}.
InterPro domains:
- IPR040379: WD repeat-containing protein 19/dyf-2 (family) [2-841]
- IPR056170: IFT121-like, zinc finger domain (domain) [780-824]
- IPR039468: WDR19, WD40 repeat domain (domain) [1-119]
- IPR056168: IF140/IFT172/WDR19, TPR domain (domain) [139-557]
Sequence:
MGIRQLFMDIEGTKVIFIDDHSQGYVFLPVVEEALLIPDIPKQCLGCLWDLTQPNIFISYDARIVNTHVFVRHSVQGTHTLMVGESKLNPGQFPLLLCGGEMALHIDGGQYATQSLSTHVVNPSNSQAANLQMLLKLRNYDEAYKLCKQMNQSSAWREFGEQAISDLEPDIAIRAYRQLGDAALVNALSELRYVEDLDMLIGCCCTLLAQYDQAKEHMLKGVYTRAALDLCRDLLQWDQALLLAHKNDPQEVPYIAREYAQQLEFNGNYTDALYHYEKGYKEDLINSKETETDALMDSSPEYEEHVRLCKMGIARTSIRAGDFRRGIQYAVELEDQQLLFDCAELLATVGHLTEAAGLYERGGFYDEACGHYIALKMWNKANNILPKVKSTKLHAAYAKAKENDGHYEEAIRSYRIAGDLDACVRIYLDHLCDPHAASEIVLESRSMDSAKLLAKFYQKIGDVEQALQFLVICGCVEEAFALAQRHNKLRRHGELLERYENAKSSDYLALAHYFEGEKYTLLAGKYYFLAREFTKALRFLLKASAFNNEEQVSLSLAIDCVATSNNEQLATQLIEFLLGEVDGVPKDPRYLFRLYMARKHYKDAAKTAVIIANQEQIAGNYKSARDLLYSMYQELRRNNLSVTAEMRHQFILLHRYTLVRIHVKLGNHLLAAKLLVQVAACISQFPEHIIPILTSTVIECHRAGLKKSAFTYASTLMRPDYRNQLDPRYAKKIESIVRKAPKGIKQLRDEIDGETMECPICDSNLANMEVTCYSCKTTLPICIATGQHIIKQLMTSCPQCDFLCFRAEMENILSENGECPMCGENVAPEQLLDVEDIRPYILAAS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0071840 (cellular component organization or biogenesis), GO:0051649 (establishment of localization in cell), GO:0016043 (cellular component organization), GO:0046907 (intracellular transport), GO:0006810 (transport), GO:0016192 (vesicle-mediated transport), GO:0016197 (endosomal transport), GO:0006996 (organelle organization), GO:0010256 (endomembrane system organization), GO:0061024 (membrane organization), GO:0016050 (vesicle organization), GO:0048193 (Golgi vesicle transport), GO:0048284 (organelle fusion), GO:0061025 (membrane fusion), GO:0006897 (endocytosis), GO:0007032 (endosome organization), GO:0006906 (vesicle fusion), GO:0090174 (organelle membrane fusion), GO:0034058 (endosomal vesicle fusion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0043227 (membrane-bounded organelle), GO:0120025 (plasma membrane bounded cell projection), GO:0005929 (cilium), GO:0097730 (non-motile cilium)
Protein: Probable electron transfer flavoprotein subunit alpha, mitochondrial (Alpha-ETF) (P78790)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).
Subcellular location: Mitochondrion matrix {ECO:0000250}.
InterPro domains:
- IPR014731: Electron transfer flavoprotein, alpha subunit, C-terminal (domain) [221-302]
- IPR029035: DHS-like NAD/FAD-binding domain superfamily (homologous_superfamily) [220-341]
- IPR033947: Electron transfer flavoprotein, alpha subunit, N-terminal (domain) [29-197]
- IPR018206: Electron transfer flavoprotein subunit alpha, conserved site (conserved_site) [285-311]
- IPR001308: Electron transfer flavoprotein alpha subunit/FixB (family) [26-341]
- IPR014729: Rossmann-like alpha/beta/alpha sandwich fold (homologous_superfamily) [28-214]
- IPR014730: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal (domain) [30-213]
Sequence:
MLRTTSRTFSRALSSSNFKINCGRRHWFSVLTLLEHQGGNLSPASLSAVEAAKRTGGDVFGFVIGKDSSQISQKVAKSVNDLKKVIYVENPSYEHNIPDQIANVLFENVKKNEISHVFSAHSTVGKGVMPRLAAMFDVMQISDIIGVVSADTFVRPTYAGNVNVTVSTKDPIKIVTVRASAFDAAPSSGEGAATVVEGIDPKPAALQEWVSENIIKNARPDLSSAERVVAGGRPLKDKETFERILTPLADKLGAAIGATRVAVDSGYADNSLQIGQTGKIIAPKLYIAVGIDGAIQHLAGIKDSKVIAAINRDENAPIFQTADVGIVGDLFEIVPELTEKL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0009055 (electron transfer activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006091 (generation of precursor metabolites and energy), GO:0015980 (energy derivation by oxidation of organic compounds), GO:0045333 (cellular respiration), GO:0009060 (aerobic respiration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Myelin basic protein (MBP) (Myelin A1 protein) (P04370)
Organism: Mus musculus (Mouse)
Function: The classic group of MBP isoforms (isoform 4-isoform 13) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined to optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function.
Subcellular location: [Isoform 13]: Myelin membrane; Peripheral membrane protein; Cytoplasmic side.; SUBCELLULAR LOCATION: [Isoform 12]: Myelin membrane; Peripheral membrane protein; Cytoplasmic side.; SUBCELLULAR LOCATION: [Isoform 11]: Myelin membrane; Peripheral membrane protein; Cytoplasmic side.; SUBCELLULAR LOCATION: [Isoform 10]: Myelin membrane; Peripheral membrane protein; Cytoplasmic side.; SUBCELLULAR LOCATION: [Isoform 9]: Myelin membrane; Peripheral membrane protein; Cytoplasmic side.; SUBCELLULAR LOCATION: [Isoform 8]: Myelin membrane; Peripheral membrane protein; Cytoplasmic side.; SUBCELLULAR LOCATION: [Isoform 7]: Myelin membrane; Peripheral membrane protein; Cytoplasmic side.; SUBCELLULAR LOCATION: [Isoform 6]: Myelin membrane; Peripheral membrane protein; Cytoplasmic side.; SUBCELLULAR LOCATION: [Isoform 5]: Myelin membrane; Peripheral membrane protein; Cytoplasmic side.; SUBCELLULAR LOCATION: [Isoform 4]: Myelin membrane; Peripheral membrane protein; Cytoplasmic side.; SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm. Nucleus.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Nucleus.; SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm. Nucleus.
InterPro domains:
- IPR000548: Myelin basic protein (family) [1-243]
Sequence:
MGNHSGKRELSAEKASKDGEIHRGEAGKKRSVGKLSQTASEDSDVFGEADAIQNNGTSAEDTAVTDSKHTADPKNNWQGAHPADPGNRPHLIRLFSRDAPGREDNTFKDRPSESDELQTIQEDPTAASGGLDVMASQKRPSQRSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFSGDRGAPKRGSGKDSHTRTTHYGSLPQKSQHGRTQDENPVVHFFKNIVTPRTPPPSQGKGGRDSRSGSPMARR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0008289 (lipid binding), GO:0005515 (protein binding), GO:0005516 (calmodulin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:0009617 (response to bacterium), GO:0043207 (response to external biotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:0043209 (myelin sheath)
Protein: Proteasome activator complex subunit 3 (Activator of multicatalytic protease subunit 3) (Proteasome activator 28 subunit gamma) (K7ENH2)
Organism: Homo sapiens (Human)
Function: Not known
InterPro domains:
- IPR003185: Proteasome activator PA28, N-terminal domain (domain) [10-69]
- IPR003186: Proteasome activator PA28, C-terminal domain (domain) [136-179]
- IPR036997: Proteasome activator PA28, C-terminal domain superfamily (homologous_superfamily) [135-179]
- IPR036252: Proteasome activator superfamily (homologous_superfamily) [5-179]
- IPR009077: Proteasome activator PA28 (family) [4-135]
- IPR036996: Proteasome activator PA28, N-terminal domain superfamily (homologous_superfamily) [5-64]
Sequence:
MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0051052 (regulation of DNA metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0006275 (regulation of DNA replication), GO:0090329 (regulation of DNA-templated DNA replication), GO:0030174 (regulation of DNA-templated DNA replication initiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Mind the gap, isoform E (A0A0C4DHF5)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
InterPro domains:
- IPR036508: Chitin binding domain superfamily (homologous_superfamily) [405-462]
- IPR002557: Chitin binding domain (domain) [398-461]
- IPR052976: Scoloptoxin-like (family) [193-530]
Sequence:
MNFFVIGFLIMQAARLACGTCVLSSDFGFILDCNFKKSGLFRVRNLGGLKAHFGLGFSLGDELGFPESLGNTESDRRRAISYKNGAPPDLVGVLPSTQQQVNPPVQHPLPEKRISSRSTGAAPYNLQQVQQQQQLQLQQQKLQQQQLQQQLKLKQLLLLQQQQQQQQQLMTEARPLPLGVPAFRPIPQKQLAATQPSAPSSTPAERRVAVDTPEPRVSVNNKLVSSIDQPHSNRTFHVANPVVSQPVAVPVFQAMPQSIARIANVGKEHRTVSSHPNYLQFEEPKFDLKDVTVEELAAAANVTVDTIKHAIYVREQQLKAEHRAQLAAKLREEFMRTSTVRTTTTTTTTTTTTPRPQKSLAEHKVSKVMNAPKEYYPVGYDKNFDDNFKSKVDLPPTSFSCAKQKHFPGLYADTDLGCMVFHVCALTDDGMVRKSFLCPENTLFDQTILKCNWWFYVDCSSSTSVYDSNIPISKSYQLMKSLTYFSKYAGGQRHEQGGDKDENALDIDSLRESMEGVARRQEQAKKAELRVEEQRSMPKEDHEHVVPAEAEQQLSN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097367 (carbohydrate derivative binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0048731 (system development), GO:0007399 (nervous system development), GO:0034330 (cell junction organization), GO:0022607 (cellular component assembly), GO:0007416 (synapse assembly), GO:0050808 (synapse organization), GO:0034329 (cell junction assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0150034 (distal axon), GO:0044306 (neuron projection terminus), GO:0042995 (cell projection), GO:0030054 (cell junction), GO:0005615 (extracellular space), GO:0098793 (presynapse), GO:0005576 (extracellular region), GO:0120025 (plasma membrane bounded cell projection), GO:0043679 (axon terminus), GO:0045202 (synapse), GO:0043083 (synaptic cleft), GO:0043195 (terminal bouton), GO:0043005 (neuron projection), GO:0030424 (axon)
Protein: Homoserine dehydrogenase (HDH) (EC 1.1.1.3) (F4K6Y8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
InterPro domains:
- IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [1-192]
- IPR001342: Homoserine dehydrogenase, catalytic (domain) [173-371]
- IPR022697: Homoserine dehydrogenase lacking ACT domain (family) [1-378]
- IPR019811: Homoserine dehydrogenase, conserved site (conserved_site) [219-241]
- IPR011147: Bifunctional aspartokinase/homoserine dehydrogenase, homoserine dehydrogenase domain (domain) [2-377]
Sequence:
MKKIPVLLMGCGGVGRHLLQHIVSCRSLHAKMGVHIRVIGVCDSKSLVAPMDVLKEELNDELLSEVCLIKSTGSALSKLGALEKGGYRVVHDSELSTETEEIAKLLGKSTGLAVVDCSASMETIEILMKAVDLGCCIVLANKKPVTSTLEHYDKLALHPRFIRHESTVGAGLPVIASLNRIISSGDPVHRIVGSLSGTLGYVMSELEDGKPLSQVVQAAKKLGYTEPDPRDDLGGMDVARKGLILARLLGKRIIMDSIKIESLYPEEMGPGLMSVDDFLHNGIVKLDQNIEERVKKASSKGCVLRYVCVIEGSSVQVGIREVSKDSPLGRLRGSDNIVEIYSRCYKEQPLVIQGAGAGNDTTAAGVLADIIDLQDLFH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0006970 (response to osmotic stress), GO:0001101 (response to acid chemical), GO:1901700 (response to oxygen-containing compound), GO:0009414 (response to water deprivation), GO:0010035 (response to inorganic substance), GO:0009415 (response to water), GO:0010033 (response to organic substance), GO:1902074 (response to salt), GO:0009651 (response to salt stress)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0043231 (intracellular membrane-bounded organelle)
Protein: RING-type E3 ubiquitin transferase (EC 2.3.2.27) (P87662)
Organism: Equid alphaherpesvirus 1 (Equine herpesvirus 1)
Function: Not known
InterPro domains:
- IPR017907: Zinc finger, RING-type, conserved site (conserved_site) [24-33]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [1-68]
- IPR018957: Zinc finger, C3HC4 RING-type (domain) [8-46]
- IPR001841: Zinc finger, RING-type (domain) [8-47]
Sequence:
MATVAERCPICLEDPSNYSMALPCLHAFCYVCITRWIRQNPTCPLCKVPVESVVHTIESDSEFKETKVSVDFDYDSEEDEDSFEGQFLAVDSGDAPANISAWNGPMAFVPLNANGTAGAPRLQPLVDWLVERLDQLFETPELALVMRNIVMDTLCEHGCNEEELTRQFWPMFHEDTVPFVTDLIIQAELCVASRPILPIARGRGVEYIDSSSSSSSSEEETDSDIEVDPNNLTDPEDTSDETSTDNSSAQAPRQEDSRPARARPGPPTRGRRRGRRPAAPGPASRRSARLRRRQPRTNSRTNGGDNGEIIDLTLDSDGPVAVVLVDRSSEGAGLFGGRFAQHVRRRTEDESARRRGNVLLRPRRQSVPPVPYPDIASTSPLIRQGGQRVRDLQRAFQTQPAEPEEMRCPHNCQRYRRNQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0044248 (cellular catabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0034655 (nucleobase-containing compound catabolic process), GO:0009057 (macromolecule catabolic process), GO:0044270 (cellular nitrogen compound catabolic process), GO:0090304 (nucleic acid metabolic process), GO:0044265 (cellular macromolecule catabolic process), GO:0019439 (aromatic compound catabolic process), GO:1901361 (organic cyclic compound catabolic process), GO:0046700 (heterocycle catabolic process), GO:0006259 (DNA metabolic process), GO:0006308 (DNA catabolic process), GO:0090305 (nucleic acid phosphodiester bond hydrolysis), GO:0090501 (RNA phosphodiester bond hydrolysis), GO:0090502 (RNA phosphodiester bond hydrolysis, endonucleolytic)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0043657 (host cell), GO:0033643 (host cell part), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0033647 (host intracellular organelle), GO:0033648 (host intracellular membrane-bounded organelle), GO:0042025 (host cell nucleus)
Protein: Palmitoyltransferase (EC 2.3.1.225) (Q9W251)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
InterPro domains:
- IPR001594: Palmitoyltransferase, DHHC domain (domain) [91-220]
- IPR039859: Palmitoyltransferase PFA4/ZDHHC16/ZDHHC20/ERF2-like (family) [12-277]
Sequence:
MRIRSNPMPSRMVDILCFLIIAVFLPVVFMFEIVVVLPAFHEPGGFFHTFTFLMAMFLVFNIKGNMIACMMIDTSVNVKKVEPPSDQLNWRECGECQKLAPPRSWHCKACKVCILKRDHHCIYTGCCIGLRNHRFFMGFIFYLFVGSVYALVYNSIYMWVIHGHIYSNWVTVLKLACPMLHLVTGSFWTNMYLVFYSLNILALAYGVLLLAYHVPIVLRGGVSADRTKESKEKYDRGVYQNLRSVFGNRMHLAWLSPLIRSDLPEDGYHWNVPTNKQD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0019538 (protein metabolic process), GO:0036211 (protein modification process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0009059 (macromolecule biosynthetic process), GO:0043412 (macromolecule modification), GO:0034645 (cellular macromolecule biosynthetic process), GO:0042157 (lipoprotein metabolic process), GO:0006497 (protein lipidation), GO:0043543 (protein acylation), GO:0042158 (lipoprotein biosynthetic process), GO:0018345 (protein palmitoylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Envelope glycoprotein UL132 (F5HGU6)
Organism: Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
Function: Not known
Subcellular location: Virion membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
InterPro domains:
- IPR021023: Envelope glycoprotein UL132 (family) [32-269]
Sequence:
MPAPRGPLRATFLALVAFGLLLQIDLSDVTNVTSSTKVPTSTSNRNSVDNATSSGPTTGINMTTTHESSVHNVRNNEIMKVLAILFYIVTGTSIFSFIAVLVAVVYSSCCKHPGRFRFADEEAVNLLDDTDDSGGSSPFGSGSRRGSQIPAGFCSSSPYQRLETRDWDEEEEASAARERMKHDPENVIYFRKDGNLDTSFVNPNYGRGSPLTIESHLSDNEEDPIRYYVSVYDELTASEMEEPSNSTSWQIPKLMKVAMQPVSLRDPEYD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0016032 (viral process), GO:0019068 (virion assembly), GO:0046755 (viral budding), GO:0019058 (viral life cycle)
Cellular Component (CC): GO:0005575 (cellular component), GO:0044423 (virion component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)