lokahq/bioreason-rl huggingface dataset:
Protein: Malate dehydrogenase 2, cytoplasmic (EC 1.1.1.37) (Cytosolic NAD-dependent malate dehydrogenase 2) (cNAD-MDH2) (Cytosolic malate dehydrogenase 2) (Cytosolic MDH2) (P57106)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes a reversible NAD-dependent dehydrogenase reaction involved in central metabolism and redox homeostasis between organelle compartments.
Subcellular location: Cytoplasm {ECO:0000250}.
InterPro domains:
- IPR001557: L-lactate/malate dehydrogenase (family) [2-329]
- IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [4-154]
- IPR001236: Lactate/malate dehydrogenase, N-terminal (domain) [6-153]
- IPR022383: Lactate/malate dehydrogenase, C-terminal (domain) [157-326]
- IPR011274: Malate dehydrogenase, NAD-dependent, cytosolic (family) [4-329]
- IPR015955: Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal (homologous_superfamily) [156-332]
- IPR001252: Malate dehydrogenase, active site (active_site) [156-168]
- IPR010945: Malate dehydrogenase, type 2 (family) [3-330]
Sequence:
MAKEPVRVLVTGAAGQIGYALVPMIARGIMLGADQPVILHMLDIPFAAEALNGVKMELVDAAFPLLKGVVATTDAVEACTGVNVAVMVGGFPRKEGMERKDVMSKNVSIYKSQASALEKHAAPNCKVLVVANPANTNALILKEFAPSIPEKNITCLTRLDHNRALGQVSERLSVPVSDVKNVIIWGNHSSTQYPDVNHATVKTSVGEKPVRELVKNDEWLNGEFISTVQQRGAAIIKARKLSSALSAASSACDHIRDWVVGTPEGTFVSMGVYSDGSYNVPAGLIYSFPVTCRNGEWTIVQGLPIDDASRKKMDLTAEELKEEKDLAYSCLS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0010035 (response to inorganic substance), GO:0010038 (response to metal ion), GO:0010043 (response to zinc ion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009532 (plastid stroma), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0005829 (cytosol), GO:0055044 (symplast), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0005576 (extracellular region), GO:0005773 (vacuole), GO:0048046 (apoplast), GO:0043229 (intracellular organelle), GO:0009506 (plasmodesma), GO:0070161 (anchoring junction), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0009536 (plastid), GO:0009570 (chloroplast stroma), GO:0000325 (plant-type vacuole), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle), GO:0005911 (cell-cell junction), GO:0005634 (nucleus)
Protein: Mycinamicin VI 2''-O-methyltransferase (EC 2.1.1.238) (Mycinamicin biosynthesis protein E) (Q83WF2)
Organism: Micromonospora griseorubida
Function: O-methyltransferase that catalyzes the conversion of mycinamicin VI to mycinamicin III in the biosynthesis of mycinamicin, a 16-membered macrolide antibiotic.
InterPro domains:
- IPR029063: S-adenosyl-L-methionine-dependent methyltransferase superfamily (homologous_superfamily) [160-382]
- IPR040800: Methyltransferase MycE, N-terminal (domain) [13-121]
Sequence:
MTAQTEFDEATVQDVVRLAGGHDSELRELTQKYDPAMISRLLVAEILSRCPPPSNDTPVLVELAIVHGSERFRHFLRVVRDSPIRPVGADEGFVGMLVEYELTELLRELFGVTHERPAGVRGTKLFPYLTDDEEAVEQIGTYLLAAQQGTEAVLAGCGSRKPDLSELSSRYFTPKFGFLHWFTPHYDRHFRDYRNQQVRVLEIGVGGYKHPEWGGGSLRMWKSFFPRGQIYGLDIMDKSHVDELRIRTIQGDQNDAEFLDRIARRYGPFDIVIDDGSHINAHVRTSFAALFPHVRPGGLYVIEDMWTAYWPGFGGQADPQECSGTSLGLLKSLIDAIQHQELPSDPNRSPGYVDRNIVGLHVYHNVAFVEKGRNDEGGIPTWIPRDFESLVQASSGGAT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016741 (transferase activity, transferring one-carbon groups), GO:0008168 (methyltransferase activity), GO:0008757 (S-adenosylmethionine-dependent methyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0016999 (antibiotic metabolic process), GO:0032259 (methylation), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0017000 (antibiotic biosynthetic process), GO:0044249 (cellular biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Diglucosylglycerate octanoyltransferase (DGG octanoyltransferase) (EC 2.3.1.273) (K5BJH8)
Organism: Mycolicibacterium hassiacum (strain DSM 44199 / CIP 105218 / JCM 12690 / 3849) (Mycobacterium hassiacum)
Function: Sugar octanoyltransferase likely involved in the biosynthesis of mycobacterial methylglucose lipopolysaccharide (MGLP). Catalyzes the transfer of an octanoyl group from octanoyl-CoA to the C6 OH of the second glucose in diglucosylglycerate (DGG). Can also use hexanoyl-CoA as acyl donor in vitro. DGG is the preferred acceptor, but to a lesser extent, GG (glucosylglycerate) can be used as substrate. DGG and GG are the two earliest intermediates in MGLP biosynthesis.
InterPro domains:
- IPR013830: SGNH hydrolase-type esterase domain (domain) [13-223]
- IPR050023: Diglucosylglycerate octanoyltransferase (family) [11-232]
- IPR036514: SGNH hydrolase superfamily (homologous_superfamily) [2-234]
Sequence:
MSGRRPTLLVFCDSLSYYGPRGGLPADDPRIWPNIVASQLDWDVELIGRVGWTSRDVWWAATQDPRAWAALPRAGAVIFATGGMDSLPSPLPTALRELIRYIRPPWLRRRVRDLYGWLQPRLSPVSRNALPPHLTAEYLEMTRGAIDFNRPGIPVVAALPSVHIADSYGRAHHGREATARAITEWARQHGVVLVDLKAAVADQVLNGRGNPDGIHWNFEAHQAVAELMLKALAEAGVPCR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0008374 (O-acyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0043933 (protein-containing complex organization), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly), GO:0051259 (protein complex oligomerization), GO:0051262 (protein tetramerization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)
Protein: Glutamate racemase (EC 5.1.1.3) (Q3XZW8)
Organism: Enterococcus faecium (strain ATCC BAA-472 / TX0016 / DO)
Function: Not known
InterPro domains:
- IPR033134: Asp/Glu racemase, active site 2 (active_site) [188-198]
- IPR004391: Glutamate racemase (family) [12-265]
- IPR001920: Asp/Glu racemase (homologous_superfamily) [13-272]
- IPR018187: Asp/Glu racemase, active site 1 (active_site) [78-86]
- IPR015942: Asp/Glu/hydantoin racemase (family) [29-220]
Sequence:
MKKRMIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARCPYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILPGTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEYHSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGEVSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0071554 (cell wall organization or biogenesis), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0044036 (cell wall macromolecule metabolic process), GO:0044085 (cellular component biogenesis), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044260 (cellular macromolecule metabolic process), GO:0042546 (cell wall biogenesis), GO:0043170 (macromolecule metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0009059 (macromolecule biosynthetic process), GO:0009273 (peptidoglycan-based cell wall biogenesis), GO:0034645 (cellular macromolecule biosynthetic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0044038 (cell wall macromolecule biosynthetic process), GO:0070589 (cellular component macromolecule biosynthetic process), GO:0006022 (aminoglycan metabolic process), GO:0030203 (glycosaminoglycan metabolic process), GO:0006023 (aminoglycan biosynthetic process), GO:0009252 (peptidoglycan biosynthetic process), GO:0006024 (glycosaminoglycan biosynthetic process), GO:0000270 (peptidoglycan metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005618 (cell wall), GO:0009274 (peptidoglycan-based cell wall)
Protein: Sulfotransferase 4, isoform A (Sulfotransferase 4, isoform B (EC 2.8.2.-)) (A1Z9J8)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
InterPro domains:
- IPR000863: Sulfotransferase domain (domain) [62-342]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [2-345]
Sequence:
MENTPLKFPHEIRDVEESTNAELLDHFHGERTGFVQVGSEGYFFPHKYKDEAERYYNFEARPDDVWIATVPRSGTTWTQELIWLVANGLDFEHAQERPLTERFPFFEFPLFVHPKIKEELQEENRDSAEALEFIEKIARPGYEALSEIPRSQRRFIKTHFPFSLMPPSVLEKKCKVIYVVRDPKDVAVSYYHLNRLFRTQGYVGDFERYWHYFQNGLNPWLPYYSHVKEAREHAHLSNVLFLRYEDMLADLPGAINSIASFLECPPKPEDMDRLLDHLSIRSFRENKSVNMHEMASVGVLNKGEAGFVRSGAKTAYQPQQEFVENPKLLKSANEWVEQNIKSFKTI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016782 (transferase activity, transferring sulphur-containing groups), GO:0008146 (sulfotransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044283 (small molecule biosynthetic process), GO:0006082 (organic acid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006520 (amino acid metabolic process), GO:0006790 (sulfur compound metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0000096 (sulfur amino acid metabolic process), GO:0044272 (sulfur compound biosynthetic process), GO:0008652 (amino acid biosynthetic process), GO:0016053 (organic acid biosynthetic process), GO:0043436 (oxoacid metabolic process), GO:1901605 (alpha-amino acid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:1901607 (alpha-amino acid biosynthetic process), GO:0006534 (cysteine metabolic process), GO:0000097 (sulfur amino acid biosynthetic process), GO:0009069 (serine family amino acid metabolic process), GO:0046394 (carboxylic acid biosynthetic process), GO:0009070 (serine family amino acid biosynthetic process), GO:0019344 (cysteine biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Scavenger receptor (Q58SM7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
InterPro domains:
- IPR035976: Sushi/SCR/CCP superfamily (homologous_superfamily) [13-69]
- IPR036024: Somatomedin B-like domain superfamily (homologous_superfamily) [279-329]
- IPR051560: MAM domain-containing protein (family) [73-302]
- IPR000998: MAM domain (domain) [74-255]
- IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [75-251]
- IPR000436: Sushi/SCR/CCP domain (domain) [18-70]
- IPR001212: Somatomedin B domain (domain) [278-329]
Sequence:
TCDRDGRLRGEKPFCASRGCARPEDPENGHVENLSLRADVVCHDGYVLVGGRTAYCDGERWSTQLGSCRRSNHTRDHSCDFESEDQCGWEAETTFRRPWKRVSTVSDIHSLRTGPRHDHTFKNESGGHYMRMETQMGAYGSYHLLSPIYPRSLTLKTACCFRFHYFMFGAGVDNLVVSVKPVSMPMATMWNRFRANCSKFEISGQQGTQWLEHTISIDEMQEDFQVIFTATDARSQFGDIAIDDVKLMTGSECGTNGFSTTTEPTAPTGSNEQPLVYDXMSCSGRCGTSISASNITNNGIVMGCGCNDECLSDETCCLNYLEECTKELLTTTEDDISSLPPTVTSTSTSTTRKSTTTTTTSTTTTSTTTTKRPTTTTTTTKATTTKRTTTTKKPTTTSTTPKPTTTTSTTPKSTTSTTSTTSTTPTTTTTINVFTTKKTTIMIPTSSTEKTTGINTTMKTRKRITWNVDPQDIEGHMDTSGSTPNPALVVLYLLLGIVLVVVLANVVNRWIIPITGSKTSSEKAVRFKKAFDSLKKQRKRNSMDDQPLCDSDNDDVEYFEEMGVDIRHRTDL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0038024 (cargo receptor activity), GO:0005044 (scavenger receptor activity), GO:0030246 (carbohydrate binding), GO:0030247 (polysaccharide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0002376 (immune system process), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051234 (establishment of localization), GO:0006950 (response to stress), GO:0051707 (response to other organism), GO:0006955 (immune response), GO:0009607 (response to biotic stimulus), GO:0006952 (defense response), GO:0043207 (response to external biotic stimulus), GO:0009617 (response to bacterium), GO:0006810 (transport), GO:0098542 (defense response to other organism), GO:0016192 (vesicle-mediated transport), GO:0042742 (defense response to bacterium), GO:0050829 (defense response to Gram-negative bacterium), GO:0006909 (phagocytosis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Junction adhesion molecule like (E9PJJ4)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
InterPro domains:
- IPR013106: Immunoglobulin V-set domain (domain) [26-136]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [26-120]
- IPR000920: Myelin P0 protein-related (family) [8-141]
- IPR007110: Immunoglobulin-like domain (domain) [11-132]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [17-138]
- IPR003599: Immunoglobulin domain subtype (domain) [27-136]
Sequence:
MFCPLKLILLPVLLDYSLGLNDLNVSPPELTVHVGDSALMGCVFQSTEDKCIFKIDWTLSPGEHAKDEYVLYYYSNLSVPIGRFQNRVHLMGDILCNDGSLLLQDVQEADQGTYICEIRLKGESQVFKKAVVLHVLPEEPKELMVHVGGLIQMGC
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0050839 (cell adhesion molecule binding), GO:0005178 (integrin binding), GO:0005102 (signaling receptor binding), GO:0046983 (protein dimerization activity), GO:0042803 (protein homodimerization activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007155 (cell adhesion), GO:0098609 (cell-cell adhesion), GO:0098742 (cell-cell adhesion via plasma-membrane adhesion molecules), GO:0007156 (homophilic cell adhesion via plasma membrane adhesion molecules)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0071944 (cell periphery), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Protein FAM24B (Q8N5W8)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Secreted {ECO:0000305}.
InterPro domains:
- IPR028122: FAM24 family (family) [1-94]
Sequence:
MPVIAGGILAALLLLIVVVLCLYFKIHNALKAAKEPEAVAVKNHNPDKVWWAKNSQAKTIATESCPALQCCEGYRMCASFDSLPPCCCDINEGL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023056 (positive regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0010647 (positive regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0010646 (regulation of cell communication), GO:0045747 (positive regulation of Notch signaling pathway), GO:0008593 (regulation of Notch signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Eukaryotic release factor 3 (Q7YZN6)
Organism: Trypanosoma brucei
Function: Not known
InterPro domains:
- IPR050100: Translation factor GTPase superfamily members (family) [1-412]
- IPR004161: Translation elongation factor EFTu-like, domain 2 (domain) [235-297]
- IPR054696: GTP-eEF1A, C-terminal domain (domain) [311-409]
- IPR000795: Translational (tr)-type GTP-binding domain (domain) [1-212]
- IPR009001: Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal (homologous_superfamily) [309-413]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [1-229]
- IPR009000: Translation protein, beta-barrel domain superfamily (homologous_superfamily) [214-300]
Sequence:
KSTISGHLLMEKGLVDQREMEKLRREAEVHHREGWEYAYVMDVSEDERTKGITRETGAAYVETEKRRITVLDAPGHKAFVPSMIGGATQADVCVLVISSRTGEFETGFEKGGQTREHAMLVRTCGVKQMICVINKMDEVNWSKERYDAILGKLKPFLRQNGYDEEKAKNLIFIPIAGLTGDNLIRETAEGVCPWYKGPTMMSFIDELVLPETKSENDVLCIPLVGSYKDEGRVFVYGKVESGSVAVGEKIQILPSKQEAVVEGISIEATEFEKCYPGDNVHLRVRGVDEGDVHAGYVGTSVPTSLRAVEYFQARVVILDVKNIICAGSRVMLHAHAAQEEVSFHKLLAKVDKKTGEVVQKDPTHVKAGDVVIARMELERALVLEPHKDFDKMGRFMLREDGKTIAIGLVMKLYESTRESLANAGKA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0005516 (calmodulin binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0007017 (microtubule-based process), GO:0051716 (cellular response to stimulus), GO:0050794 (regulation of cellular process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0035556 (intracellular signal transduction), GO:0019932 (second-messenger-mediated signaling), GO:0019722 (calcium-mediated signaling)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Cytoglobin-2 (Nitric oxygen dioxygenase CYGB) (EC 1.14.12.-) (Nitrite reductase CYGB) (EC 1.7.-.-) (Pseudoperoxidase CYGB) (EC 1.11.1.-) (Superoxide dismutase CYGB) (EC 1.15.1.1) (Q575S8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q8WWM9}. Nucleus {ECO:0000250|UniProtKB:Q8WWM9}.
InterPro domains:
- IPR000971: Globin (domain) [18-167]
- IPR009050: Globin-like superfamily (homologous_superfamily) [18-169]
- IPR012292: Globin/Protoglobin (homologous_superfamily) [1-171]
- IPR013314: Globin, lamprey/hagfish type (family) [1-178]
Sequence:
MEKEREDEETEGRERPEPLTDVERGIIKDTWARVYASCEDVGVTILIRFFVNFPSAKQYFSQFQDMEDPEEMEKSSQLRKHARRVMNAINTVVENLHDPEKVSSVLVLVGKAHAFKYKVEPIYFKILSGVILEILAEEFGECFTPEVQTSWSKLMAALYWHITGAYTEVGWVKLSSSAV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0036094 (small molecule binding), GO:0016491 (oxidoreductase activity), GO:0019825 (oxygen binding), GO:0016661 (oxidoreductase activity, acting on other nitrogenous compounds as donors)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0010035 (response to inorganic substance), GO:0010038 (response to metal ion), GO:0046686 (response to cadmium ion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)