lokahq/bioreason-rl huggingface dataset:
Protein: Lambda-carrageenase (EC 3.2.1.162) (Q0JRK4)
Organism: Pseudoalteromonas carrageenovora (Alteromonas carrageenovora)
Function: Hydrolyzes lambda-carrageenan with inversion of anomeric configuration. Does not hydrolyze iota- and kappa-carrageenans, agarose or porphyran.
Subcellular location: Secreted {ECO:0000269|PubMed:17269933}.
InterPro domains:
- IPR057420: Lambda-carrageenase, beta-propeller domain (domain) [53-367]
- IPR057421: Lambda-carrageenase, middle domain (domain) [453-823]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [24-220]
- IPR011047: Quinoprotein alcohol dehydrogenase-like superfamily (homologous_superfamily) [49-539]
- IPR057422: Lambda-carrageenase, C-terminal domain (domain) [851-929]
Sequence:
MKIKILSAMVASSLLIGCVIPTVKASQSAIKSIETNRTITKVRTGMLSGGSSIITTSYEGTVAAYKFNGEKLWENELSGFMNHDIWVQDINGDGLVEIFAANADGNVYCINSDGSLKWTFGLNEVPMNSVTVISDADKKYVVAGGYDKNLYYISTNGELLKTIESGTYSEEGVFGDGVKPEARTHTVNFVRPVKSSDGTEKLVVLGTNNSLQSSGRFYIFEPFADLPSEKSRISIKKGIGDLRTVDFDNDGNDELTLGNSAQIGDAAISVMNLDDLSQKKSQINDIARRIDRFGYRVAQTEVVMNEGTPTYLTLFGSRILLTPESFDVNDSEILANKYSYYDMWKDKSSNKLVLASAQSGGSQVHIIDTSNPSWKSAYEELEPQGKLAAIQENTRAIERQLSNFQKPTRERAPLPVYFISESRNEIPTTIERSEFLYDSPVFLNYSTLPNVENWDRSEVLADNPKYRDKRDRRKNYTLSSEEMFNKLSAGYDNSDGISQWAGHGNDPYMISLATMKRIISSGDGKKTVNIYPEIEGHGDAFNKVLSDHFYPLAEFSSENNANLFMRNKHTFWQSTIYAPEWSELRSGRLADAFVPAMEETTDKSMEMSVAGRMGLWAAGSVDNWGERYARDNPSFDRLRQHSHQMVPNHALRQIIYKIASGARYINNFGFNQEYMSLAWELIGKGALYVPKREELLSLSPVHISMKEPDPIYRETSNNVKWTTFYDEEKDSIPYVFSRLNGTWPGAKTLPWDYSNYAADTKERRLDFIPKFPKGLVLITPVQQGKFKDEGTVRGTLADNMHPIYKDIMKEYITDGKNYYNPNGEQVMAADSVRYRQIKNKIEEKSNLLPMTVSGEAAWVVAQSAEKHLRLTLVDSGYLNPSNKVAKVKFNSVTPVAIVDVLSGETFSPDSNGVVEIPVLAGAFRFIDVKITEDLRNMQSSTL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:1901575 (organic substance catabolic process), GO:0043170 (macromolecule metabolic process), GO:0005975 (carbohydrate metabolic process), GO:0016052 (carbohydrate catabolic process), GO:0009057 (macromolecule catabolic process), GO:0005976 (polysaccharide metabolic process), GO:0000272 (polysaccharide catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: PslL (Q9I1M8)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
InterPro domains:
- IPR004268: Peptidoglycan biosynthesis protein MurJ (family) [30-443]
Sequence:
MLGSAFWLTLATLLGLCLGFAREWLLVASWGAGERSDAFLIALFLPEALRMSLAGGVLSAAALPLFLERQGERRLDWLAAILPALLGIAVALSLLLLAAAPWLVRLLGPGLAETASAQAAANLRVLAWCVPGLMLHALFSIPLQAAERFVLAGLGSLLFNLPPVLYLALHGQASQPEQLALACLLGSLLMPLVLLPSLWIEGWRPWHWRLSGVELGELGGRIAPLLLSNAASQGLALVERLVASLLGEGAVTWVNLARKLMNLPLIALMSLNQVLLGMMSRRQGGERLALLRRGLETASLLTLPAGVGLVAAAPGLVALLLPRQTAGSPLPALLAWFAVPLVFGAWNALLARYAYAAGDTRLPLRCELLGSALNAALLAVLPLIFGLPGIPLAALGGVLCTALLLMRRQALLGALPWARLWLLNALAMALAAGLLFRIDGIWLQLGLGTVAGCLALLGMALWLRPWRTD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0005319 (lipid transporter activity), GO:0140303 (intramembrane lipid transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0044249 (cellular biosynthetic process), GO:0005975 (carbohydrate metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0044262 (cellular carbohydrate metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0044264 (cellular polysaccharide metabolic process), GO:0016051 (carbohydrate biosynthetic process), GO:0005976 (polysaccharide metabolic process), GO:0034637 (cellular carbohydrate biosynthetic process), GO:0000271 (polysaccharide biosynthetic process), GO:0033692 (cellular polysaccharide biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098552 (side of membrane), GO:0009986 (cell surface), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0009897 (external side of plasma membrane), GO:0005886 (plasma membrane)
Protein: Exostosin glycosyltransferase 1 (G3V901)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004648}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004648}.
InterPro domains:
- IPR040911: Exostosin, GT47 domain (domain) [111-395]
- IPR029044: Nucleotide-diphospho-sugar transferases (homologous_superfamily) [478-740]
- IPR015338: Glycosyl transferase 64 domain (domain) [480-729]
- IPR004263: Exostosin-like (family) [72-743]
Sequence:
MQAKKRYFILLSAGSCLALLFYFGGVQFRASRSHSRREEHSGRNGLHQPSPDHFWPRFPDALRPFFPWDQLENEDSSVHISPRQKRDANSSIYKGKKCRMESCFDFTLCKKNGFKVYVYPQQKGEKIAESYQNILAAIEGSRFYTSDPSQACLFVLSLDTLDRDQLSPQYVHNLRSKVQSLHLWNNGRNHLIFNLYSGTWPDYTEDVGFDIGQAMLAKASISTENFRPNFDVSIPLFSKDHPRTGGERGFLKFNTIPPLRKYMLVFKGKRYLTGIGSDTRNALYHVHNGEDVLLLTTCKHGKDWQKHKDSRCDRDNTEYEKYDYREMLHNATFCLVPRGRRLGSFRFLEALQAACVPVMLSNGWELPFSEVINWNQAAVIGDERLLLQIPSTIRSIHQDKILALRQQTQFLWEAYFSSVEKIVLTTLEIIQDRIFKHISRNSLIWNKHPGGLFVLPQYSSYLGDFPYYYANLGLKPPSKFTAVIHAVTPLVSQSQPVLKLLVAAAKSQYCAQIIVLWNCDKPLPAKHRWPATAVPVIVIEGESKVMSSRFLPYDNIITDAVLSLDEDTVLSTTEVDFAFTVWQSFPERIVGYPARSHFWDNSKERWGYTSKWTNDYSMVLTGAAIYHKYYHYLYSHYLPASLKNMVDQLANCEDILMNFLVSAVTKLPPIKVTQKKQYKETMMGQTSRASRWADPDHFAQRQSCMNTFASWFGYMPLIHSQMRLDPVLFKDQVSILRKKYRDIERL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0016757 (glycosyltransferase activity), GO:0016758 (hexosyltransferase activity), GO:0008194 (UDP-glycosyltransferase activity), GO:0008375 (acetylglucosaminyltransferase activity), GO:0015020 (glucuronosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0005794 (Golgi apparatus), GO:0031090 (organelle membrane), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098827 (endoplasmic reticulum subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0005789 (endoplasmic reticulum membrane), GO:0098588 (bounding membrane of organelle), GO:0000139 (Golgi membrane)
Protein: RE01730p (Secreted Wg-interacting molecule, isoform A) (Secreted Wg-interacting molecule, isoform B) (Q7JWQ7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
InterPro domains:
- IPR013128: Peptidase C1A (family) [196-412]
- IPR025661: Cysteine peptidase, asparagine active site (active_site) [383-402]
- IPR000668: Peptidase C1A, papain C-terminal (domain) [187-419]
- IPR038765: Papain-like cysteine peptidase superfamily (homologous_superfamily) [128-420]
- IPR001212: Somatomedin B domain (domain) [38-86]
- IPR025660: Cysteine peptidase, histidine active site (active_site) [365-375]
Sequence:
MSIKCVHLVGLLVLLMGGANALFDHTLKRDFPGPYCARENTCCKDRHDGCSVPISNTLCYCDEFCDRDDSSDCCPDYRSFCIGEVDPIISCEHNGVYFSKYNTTWDNCNECRCLEGGSVQCDEDLCLTDDAIVHSVNSIHRLGWSARKYDQWWGRKYSEGLKLRLGTKEPTYRVKAMTRLKNPTDGLPSSFNALDKWSSYISEVPDQGWCGASWVLSTTSVASDRFAIQSKGKENVQLSAQNILSCTRRQQGCEGGHLDAAWRYLHKKGVVDENCYPYTQHRDTCKIRHNSRSLRANGCQKPVNVDRDSLYTVGPAYSLNREADIMAEIFHSGPVQATMRVNRDFFAYSGGVYRETAANRKAPTGFHSVKLVGWGEEHNGEKYWIAANSWGSWWGEHGYFRILRGSNECGIEEYVLASWPYVYSYYNVKSA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0017147 (Wnt-protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0051641 (cellular localization), GO:0023056 (positive regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0051234 (establishment of localization), GO:0023051 (regulation of signaling), GO:0033036 (macromolecule localization), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0010646 (regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0070727 (cellular macromolecule localization), GO:0010647 (positive regulation of cell communication), GO:0045184 (establishment of protein localization), GO:0035592 (establishment of protein localization to extracellular region), GO:0030111 (regulation of Wnt signaling pathway), GO:0008104 (protein localization), GO:0030177 (positive regulation of Wnt signaling pathway), GO:0071692 (protein localization to extracellular region), GO:0060828 (regulation of canonical Wnt signaling pathway), GO:0090263 (positive regulation of canonical Wnt signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Peptide YY (PYY) (Peptide tyrosine tyrosine) [Cleaved into: Peptide YY(3-36) (PYY-II)] (Q9EPS2)
Organism: Mus musculus (Mouse)
Function: This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.
Subcellular location: Secreted.
InterPro domains:
- IPR020392: Pancreatic hormone-like, conserved site (conserved_site) [48-64]
- IPR001955: Pancreatic hormone-like (family) [29-65]
Sequence:
MVAVRRPWPVTVAMLLILLACLGALVDAYPAKPEAPGEDASPEELSRYYASLRHYLNLVTRQRYGKRDVPAALFSKLLFTDDSDSENLPFRPEGLDQW
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0001664 (G protein-coupled receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0007267 (cell-cell signaling), GO:0065008 (regulation of biological quality), GO:0003008 (system process), GO:0007154 (cell communication), GO:0008217 (regulation of blood pressure), GO:0003013 (circulatory system process), GO:0099536 (synaptic signaling), GO:0008015 (blood circulation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Corrinoid adenosyltransferase MMAB (EC 2.5.1.-) (ATP:co(I)rrinoid adenosyltransferase MMAB) (Methylmalonic aciduria type B homolog) (Q58D49)
Organism: Bos taurus (Bovine)
Function: Converts cob(I)alamin to adenosylcobalamin (adenosylcob(III)alamin), a coenzyme for methylmalonyl-CoA mutase, therefore participates in the final step of the vitamin B12 conversion. Generates adenosylcobalamin (AdoCbl) and directly delivers the cofactor to MUT in a transfer that is stimulated by ATP-binding to MMAB and gated by MMAA (By similarity).
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q96EY8}.
InterPro domains:
- IPR016030: Cobalamin adenosyltransferase-like (domain) [52-220]
- IPR029499: Corrinoid adenosyltransferase, PduO-type (family) [21-235]
- IPR036451: Cobalamin adenosyltransferase-like superfamily (homologous_superfamily) [51-241]
Sequence:
MAVWGPGGRLGLRGCLGARKLLCPRFQSRGPQGVEDGDRPQPSSKTPKVPKIYTKTGDKGFSSTFTGERRSKDDQVFEAVGTTDELSSAIGFAMELIAEKGHPFVEELQKIQCSLQDVGSALATPRSSAREAHLKHATFEAGPILELEQWIDKYSRQLPPLTAFILPSGGKSSSALHFCRAVCRRAERRVVPLVQTGETDANVVKFLNRLSDYLFTLARYTAMKEGNPEKIYKKNDLSDRT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016661 (oxidoreductase activity, acting on other nitrogenous compounds as donors), GO:0016662 (oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044281 (small molecule metabolic process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0046483 (heterocycle metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006766 (vitamin metabolic process), GO:0006767 (water-soluble vitamin metabolic process), GO:0033013 (tetrapyrrole metabolic process), GO:0009235 (cobalamin metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005740 (mitochondrial envelope), GO:0019866 (organelle inner membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031966 (mitochondrial membrane), GO:0005743 (mitochondrial inner membrane)
Protein: RAB11 family interacting protein 2 (A0A8I6A5U7)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004308}. Recycling endosome {ECO:0000256|ARBA:ARBA00004172}.
InterPro domains:
- IPR019018: Rab-binding domain FIP-RBD (domain) [437-499]
- IPR035892: C2 domain superfamily (homologous_superfamily) [3-158]
- IPR000008: C2 domain (domain) [1-122]
- IPR037245: FIP-RBD, C-terminal domain superfamily (homologous_superfamily) [469-501]
- IPR037789: Rab11-family interacting protein class I (family) [1-425]
Sequence:
MMLSEQAQKWFPTHVQVTVLQAKDLKPKGKSGTNDTYTIIQLGKEKYSTSVAEKTLEPVWKEEASFELPGLLMQGNPEKYILFLIVMHRSLVGLDKFLGQVAINLNDIFEDKQRRKTEWFRLESKQGKRIKNRGEIKVNIQFMRNNMTASMFDLSMKDKTRSPFAKLKDKMKGRKSDGVFSDTSSAIVPSTHMPDANPEFSSGEMQMKSKPKKPFLLGPQRLSSAHSMSDLTGSHLSSEKLKSSTVGPTHLLSHQINSFGVVPESGSLKSPHRRTLSFDTSKLNQPGSIVDEGEHCFGRQSDPFTNVTASLPQKFATLPRKKNPFEESSEPWDSSTNLFSKPIEVRKESKREKREKVSLFERVTGKRDSRRSDKLNNGGSDSPCDLKSPSAFNENRQDYFEYESTNPFTAKFRASTIMPSSSFHMNPTSSDDLRKIPDSNPFDATAGYRSLTYEEVLQELVKHKELLRRKDTHIRELEDYIDNLLVRVMEETPSILRVPYEPSRKAASLCCRQVFLPLWTLP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0019900 (kinase binding), GO:0019901 (protein kinase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:1903829 (positive regulation of protein localization), GO:0060341 (regulation of cellular localization), GO:0032880 (regulation of protein localization), GO:1904377 (positive regulation of protein localization to cell periphery), GO:1905477 (positive regulation of protein localization to membrane), GO:1904375 (regulation of protein localization to cell periphery), GO:1905475 (regulation of protein localization to membrane), GO:1903078 (positive regulation of protein localization to plasma membrane), GO:1903076 (regulation of protein localization to plasma membrane)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0048471 (perinuclear region of cytoplasm), GO:0005737 (cytoplasm), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle)
Protein: PRRG2 protein (Q8TAS3)
Organism: Homo sapiens (Human)
Function: Not known
InterPro domains:
- IPR050442: Peptidase S1 family, coagulation factors (family) [6-73]
- IPR035972: Gamma-carboxyglutamic acid-rich (GLA) domain superfamily (homologous_superfamily) [28-82]
- IPR000294: Gamma-carboxyglutamic acid-rich (GLA) domain (domain) [5-73]
- IPR017857: Coagulation factor-like, Gla domain superfamily (homologous_superfamily) [27-72]
Sequence:
MSLGPEVFLGPPEAQSFLSSHTRIPRANHWDLELLTPGNLERECLEERCSWEEAREYFEDNTLTERFWESYIYNGKGGRGRVDVASLAVGLTCGILLIVLAGLGAFWYLRWRQHRGQQPCPQEAGLISPLSPLNPLGPPTPLPPPPPPPPGLPTYEQALAASGVHDAPPPPYTSLRRPH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0050793 (regulation of developmental process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0051241 (negative regulation of multicellular organismal process), GO:0051239 (regulation of multicellular organismal process), GO:0051093 (negative regulation of developmental process), GO:0048522 (positive regulation of cellular process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0045596 (negative regulation of cell differentiation), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0045595 (regulation of cell differentiation), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:1901343 (negative regulation of vasculature development), GO:0010562 (positive regulation of phosphorus metabolic process), GO:0051246 (regulation of protein metabolic process), GO:0051247 (positive regulation of protein metabolic process), GO:0045765 (regulation of angiogenesis), GO:0051174 (regulation of phosphorus metabolic process), GO:2000181 (negative regulation of blood vessel morphogenesis), GO:0016525 (negative regulation of angiogenesis), GO:0031399 (regulation of protein modification process), GO:0045937 (positive regulation of phosphate metabolic process), GO:0031401 (positive regulation of protein modification process), GO:0019220 (regulation of phosphate metabolic process), GO:0042325 (regulation of phosphorylation), GO:0001932 (regulation of protein phosphorylation), GO:0042327 (positive regulation of phosphorylation), GO:0001934 (positive regulation of protein phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Nuclear factor of activated T-cells 2 (A0A8I6G9R9)
Organism: Rattus norvegicus (Rat)
Function: Not known
InterPro domains:
- IPR008366: Nuclear factor of activated T cells (NFAT) (family) [29-600]
- IPR037059: Rel homology domain (RHD), DNA-binding domain superfamily (homologous_superfamily) [379-553]
- IPR008967: p53-like transcription factor, DNA-binding domain superfamily (homologous_superfamily) [381-557]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [554-610]
- IPR014756: Immunoglobulin E-set (homologous_superfamily) [559-619]
- IPR011539: Rel homology domain, DNA-binding domain (domain) [374-556]
Sequence:
MQRSALRRPGPRQPLRTMGSADREEPIAHKAISSPSGLAYPDDVLDYGLKPCNPLASLSGEPPGRFGESDSIGFQNFLSPAKPAGASGPSPRIEITPSHELMQAGGALRGRDAGLSPEQPALALAGMAASPRFTLPVPGFEGYREPLCLSPASSGSSASFISDTFSPYTSPCVSPNNAGPDDLCPQFQNIPAHYSPRTSPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVAPLPAASPQRSRSPSPQPSPHVAPQDDGIPAGYPPTAGSAVLMDALNSLATDSPCGIPSKIWKTSPDPTPVSTAPSKAGLARHIYPAVEFLGPCEQEERRNSAPESILLVPPTWPKQLVPAIPICSIPVTASLPPLEWPLSNQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPEPSGRIVSLQAASNPIECSQRSAHELPMVERQDMDSCLVYGGQQMILTGQNFTAESKVVFMEKTTGPAGTCETQPLPISLISADRLSPWLSRLQRNPPARSVFRCSVLLPAPGSSLVLLAL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008134 (transcription factor binding), GO:0001221 (transcription coregulator binding), GO:0001223 (transcription coactivator binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023057 (negative regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0010646 (regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0030111 (regulation of Wnt signaling pathway), GO:0030178 (negative regulation of Wnt signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)