Protein: ABC transporter B family member 23, mitochondrial (ABC transporter ABCB.23) (AtABCB23) (ABC transporter of the mitochondrion 1) (AtATM1) (Iron-sulfur clusters transporter ATM1) (Protein STARIK 2) (Q9FUT3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins. Not involved in the export of cyclic pyranopterin monophosphate (cPMP) from mitochondria into the cytosol.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:17517886, ECO:0000305|PubMed:25732537}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:17517886}.
InterPro domains:
- IPR017871: ABC transporter-like, conserved site (conserved_site) [574-588]
- IPR036640: ABC transporter type 1, transmembrane domain superfamily (homologous_superfamily) [90-423]
- IPR003593: AAA+ ATPase domain (domain) [462-648]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [428-677]
- IPR039421: Type 1 protein exporter (family) [74-668]
- IPR003439: ABC transporter-like, ATP-binding domain (domain) [437-671]
- IPR011527: ABC transporter type 1, transmembrane domain (domain) [103-400]
Sequence:
MMRGSRFLLSRASLYHRLRSDHHHHSFSSFIKRSSIQRSPAINAFFTDPSPSPSPVNARVFFFSTSTSTPNQDQTKTASSKKILRTISSYLWMKDNPELRFRVIAALACLIGAKFLNVQVPFLFKLSIDLLSSYSSSTITDSNPYLLAAFATPSSVLIGYGIARSGSSAFNELRTAVFSKVSLRTIRSVSRKVLSHLHDLDLRYHLNRETGALNRIIDRGSRAINTILSAMVFNVVPTILEISMVTGILAYNFGPVFALITSLSVGSYIAFTLVVTQYRTKFRKAMNQADNDASTRAIDSLVNYETVKYFNNEDYEARKYDDLLGRYEDAALQTQKSLAFLDFGQSFIFSTALSTSMVLCSQGIMNGEMTVGDLVMVNGLLFQLSLPLYFLGGVYRETVQGLVDMKSLFQLLEERSDIGDKDTETKLPPLVLRGGSISFENVHFSYLPERKILDGISFEVPAGKSVAIVGSSGSGKSTILRMIFRFFDTDSGNVRIDGQDIKEVTLESLRSCIGVVPQDTVLFNDTIFHNIHYGNLSATEEEVYDAARRAVIHDTIMKFPDKYSTAVGERGLMLSGGEKQRVALARAFLKSPAILLCDEATNALDSKTEAEIMKTFRSLASNRTCIFIAHRLTTAMQCDEIIVMEKGKVVEKGTHQVLLEKSGRYAKLWTQQNSTLEV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0015562 (efflux transmembrane transporter activity), GO:0015103 (inorganic anion transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050789 (regulation of biological process), GO:0042592 (homeostatic process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009058 (biosynthetic process), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0048878 (chemical homeostasis), GO:0019725 (cellular homeostasis), GO:0051189 (prosthetic group metabolic process), GO:0044237 (cellular metabolic process), GO:0050794 (regulation of cellular process), GO:0065009 (regulation of molecular function), GO:0044238 (primary metabolic process), GO:0050801 (monoatomic ion homeostasis), GO:0050790 (regulation of catalytic activity), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0048731 (system development), GO:0019637 (organophosphate metabolic process), GO:0019538 (protein metabolic process), GO:0044249 (cellular biosynthetic process), GO:0098771 (inorganic ion homeostasis), GO:0048229 (gametophyte development), GO:0043545 (molybdopterin cofactor metabolic process), GO:0043170 (macromolecule metabolic process), GO:0006793 (phosphorus metabolic process), GO:0099402 (plant organ development), GO:0055082 (intracellular chemical homeostasis), GO:0010035 (response to inorganic substance), GO:1901360 (organic cyclic compound metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0016043 (cellular component organization), GO:0010038 (response to metal ion), GO:0048364 (root development), GO:1901362 (organic cyclic compound biosynthetic process), GO:0009555 (pollen development), GO:1901401 (regulation of tetrapyrrole metabolic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0032324 (molybdopterin cofactor biosynthetic process), GO:0006873 (intracellular monoatomic ion homeostasis), GO:0055072 (iron ion homeostasis), GO:0022622 (root system development), GO:1901566 (organonitrogen compound biosynthetic process), GO:0055080 (monoatomic cation homeostasis), GO:0018130 (heterocycle biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019720 (Mo-molybdopterin cofactor metabolic process), GO:0090407 (organophosphate biosynthetic process), GO:0006996 (organelle organization), GO:0006777 (Mo-molybdopterin cofactor biosynthetic process), GO:0051276 (chromosome organization), GO:0006879 (intracellular iron ion homeostasis), GO:0030003 (intracellular monoatomic cation homeostasis), GO:1901463 (regulation of tetrapyrrole biosynthetic process), GO:0090056 (regulation of chlorophyll metabolic process), GO:0046686 (response to cadmium ion), GO:0009657 (plastid organization), GO:0010288 (response to lead ion), GO:0009658 (chloroplast organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)