lokahq/bioreason-rl huggingface dataset:
Protein: Ubiquitin carboxyl-terminal hydrolase (Q4V973)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR028889: Ubiquitin specific protease UPS, catalytic domain (domain) [324-832]
- IPR015940: Ubiquitin-associated domain (domain) [632-739]
- IPR018200: Ubiquitin specific protease, conserved site (conserved_site) [325-795]
- IPR050164: Ubiquitin carboxyl-terminal hydrolases (family) [179-832]
- IPR016652: Ubiquitinyl hydrolase (family) [15-832]
- IPR001607: Zinc finger, UBP-type (domain) [173-281]
- IPR009060: UBA-like superfamily (homologous_superfamily) [685-744]
- IPR038765: Papain-like cysteine peptidase superfamily (homologous_superfamily) [320-832]
- IPR001394: Peptidase C19, ubiquitin carboxyl-terminal hydrolase (domain) [324-829]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [2-268]
- IPR041432: Ubiquitinyl hydrolase, variant UBP zinc finger (domain) [15-77]
Sequence:
MTEVSEILMSVLSAIRVPRPGDRVHKDECAFSFSSPESEGGLYVCMNSFLGFGSKYVDRHHAKTGQRAYLHITRTRKTQKEDDPNSGSGDPPKKKPTRLAIGIEGGFDVEQEQYEEEVKVVLFPDRQEVTLDDLSSMPDVVRERVSLSVAELQAADSVSHTLQVQQWDGEVRQESKHAAELKQLDNGLKIPPSGWKCEVCELQENLWMNLTDGKVLCGRRYFDGSGGNNHALLYYQQTGYPLAVKLGTITPDGADVYSYDEDDMVLDSKLPEHLSHFGIDMMTMEKTERTMTELEIAVNQRVGEWEVIQESGTTLRPLWGPGLTGMKNLGNSCYLNSVMQVLFTIPDFQTKYVSNIDKIFDEAPSDPTQDFKTQVAKLGYGLLSGEYSKPAPDPADEPNTSAEPRGDQVGIAPRMFKALVGRGHPEFSTNRQQDAQEFLLHFINMVERNCRSGMNPSEAFRFLVEEKIVCQQSQKAKYTQRVDYIVQLPVPMDQATNMDELQEAERRREEAESSGAPPPVAPRAQIPFAACLAALSEPETLTDFWSSAVQAKTTATKTTRFASFPDHLVIQIKKFTFGLDWVPKKLDVSIDVPETLDLNALRAMGQQPGEELLPEVAPPPLMTPDVEVKAPVLDDSTVSQLCEMGFPLEACRKAVYYTGNTGIDAAMNWVMGHMDDPDFAAPLVLPGSSSAPGTTPTESLPEEHLATIVSMGFSRDQATRALKATNNVLERAVDWIFSHLDDLESMDVSEGGRSEGGSEASREPPPGPRVRDGTGKYELFAFISHMGSSTMCGHYVCHIKKDQQWVIFNDQKVCASEKPPKDLGYLYFYRRVVE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0019783 (ubiquitin-like protein peptidase activity), GO:0101005 (deubiquitinase activity), GO:1990380 (K48-linked deubiquitinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0007389 (pattern specification process), GO:1904888 (cranial skeletal system development), GO:0003002 (regionalization), GO:0009953 (dorsal/ventral pattern formation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: P2X purinoceptor (A0A8M9PCJ8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Extracellular ATP-activated non-selective cation channel. Plays particularly important role in sensory neurons where its activation is critical for gustatory, nociceptive responses, visceral reflexes and sensory hypersensitization
Subcellular location: Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein
InterPro domains:
- IPR059116: ATP P2X receptor-like (family) [9-378]
- IPR053792: ATP P2X receptor, conserved site (conserved_site) [246-272]
- IPR027309: P2X purinoreceptor extracellular domain superfamily (homologous_superfamily) [61-338]
- IPR003046: P2X3 purinoceptor (family) [76-410]
- IPR001429: P2X purinoreceptor (family) [8-391]
Sequence:
MQQCSGKMWTCITDFFTYETTKSVVVKSWTIGIINRVVQLLIITYFIGWVFLYEKAYQVRDTAIESSVMTKVKGFGEYNNRIMDVADYVTPTQGASVFCVITKLITTENQVQGNCPESELKFKCENDIRCKQLMTKPSSNGLLTGRCVHFNTTHKTCEIKGWCPAEIDEVQPNPMMEVENFTIFIKNSIRFPRFNFTKGNFLANINSSYIKGCNFDFERNMYCPIFKVGDVIRFAQQNFTTLATKGGVIGIKIAWVCDLDKADDECKPAYSFTRLDAMSEKTTVSPGYNFRYAKYFKMENGTEYRTLLKAYAIRFDVLVNGDAGKFDMIPTLINMVAAFTSVGVGTVLCDIILLNFLKGADQYKAKKFEEVSDSNIQSSGSLYRTRDHSQQSIKTDEKFSNDSGAFSIERYS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0015267 (channel activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0005261 (monoatomic cation channel activity), GO:0022839 (monoatomic ion gated channel activity), GO:0022836 (gated channel activity), GO:0099094 (ligand-gated monoatomic cation channel activity), GO:0022834 (ligand-gated channel activity), GO:0015276 (ligand-gated monoatomic ion channel activity), GO:0035381 (ATP-gated ion channel activity), GO:0004931 (extracellularly ATP-gated monoatomic cation channel activity), GO:0005230 (extracellular ligand-gated monoatomic ion channel activity), GO:0005231 (excitatory extracellular ligand-gated monoatomic ion channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0006811 (monoatomic ion transport), GO:0006812 (monoatomic cation transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: DIRAS family, GTP-binding RAS-like 1b (A0A8N7UYZ0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Displays low GTPase activity and exists predominantly in the GTP-bound form
Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side
InterPro domains:
- IPR001806: Small GTPase (family) [3-198]
- IPR020849: Small GTPase, Ras-type (family) [7-180]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [1-176]
- IPR005225: Small GTP-binding domain (domain) [6-164]
Sequence:
MPEQSNDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTVEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSKQSLEELKPIYQQILAIKGNVENIPIMLVGNKSDETQREVKTEDGEAQSKTWKCAFMETSAKTNHNVTELFQELLNLEKKRSMSLNIDGKRSGKQSRADKLKGKCSVM
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0021675 (nerve development), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0022008 (neurogenesis), GO:0061548 (ganglion development), GO:0007399 (nervous system development), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0021545 (cranial nerve development), GO:0061550 (cranial ganglion development), GO:0048699 (generation of neurons)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Peptide-methionine (R)-S-oxide reductase (A0A8M1P8M4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues
InterPro domains:
- IPR002579: Peptide methionine sulphoxide reductase MrsB domain (domain) [44-180]
- IPR011057: Mss4-like superfamily (homologous_superfamily) [52-181]
- IPR028427: Peptide methionine sulfoxide reductase MsrB (family) [23-183]
Sequence:
MAVRLLRSMAPCASMALLQCMRSHKTTRPLLILTTPAALGTCRSKKTWPKTFPEEELRKRLTPMQYHVTQQKGTESAFTGKYVDNKEEGTYHCVVCGAPLFMSEKKFDSGSGWPSFFDLINKDAIAQTDDFSYGMHRVETTCSQCGAHLGHLFDDGPRPTKKRYCINSASLSFQPKNSATEEVEASGAAGQSSTSKNEEL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016667 (oxidoreductase activity, acting on a sulfur group of donors), GO:0016671 (oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0048856 (anatomical structure development), GO:0048513 (animal organ development), GO:0048839 (inner ear development), GO:0007423 (sensory organ development), GO:0043583 (ear development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Pannexin (A0A8M6YTH1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Structural component of the gap junctions and the hemichannels
Subcellular location: Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi- pass membrane protein
InterPro domains:
- IPR039099: Pannexin (family) [11-477]
- IPR000990: Innexin (family) [43-416]
Sequence:
MQNILEQNLDMATALLAGEKLKELIMPGSTQDEKGGVLAGLMVQLKLELPFDRVVTIGTVIIPILLVTLVFTRNFAEESIYCYTPHNFTRDQALYARGYCWTELRDAVPGVDPELRPSLFEHKFLPYALLAFAGIMYIPALGWEFMASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKGPGITERERREIIENAEKEKSPEQNLFEKYLERRGQSNFLAKLYLARHLAIICLSSIPITYLSAYYARQRQNEFTCALGGPPDTSSIPELRLNVNCKLPAVQLQRIMAAVDIALLCTMNLIILLNLLHLFVVRKSNFVFDKLHKVGIKTRRRWQKSPFCDINILAMFCNENRDHIKSLNRLDFITNESDLMYDNVVRQLLAALAQSNHDATPTVRDSGIQTIDPSMDPSVLGVGELGGEPSVIKRPRKKMKWIPTSNPLPQSFKEPLTLTRLENSIKAEKPKPVRRKNVADSIIAPLLDSKSTQYPPTSKDTYNTQKKHSLNLSLDVHPYMLTIQKAETVNPEPPPVEHSISSVYIEGPHTVVHVSSTLTEKKESPPLSTTTAFSTATLPTNSYLNGGTASMPPPLDSPKVIGPLNQETEPESQPVPFSRNPSLPLLSIHHTLYEKDEDDQNRRLARPGELIAAGEC
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015267 (channel activity), GO:0022829 (wide pore channel activity), GO:0005243 (gap junction channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0006950 (response to stress), GO:0002931 (response to ischemia)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle)
Protein: Interleukin 10 receptor, beta (A0A8M1N7Q2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Together with IFNAR2, forms the heterodimeric receptor for type I interferons (including interferons alpha, beta, epsilon, omega and kappa). Type I interferon binding activates the JAK-STAT signaling cascade, resulting in transcriptional activation or repression of interferon-regulated genes that encode the effectors of the interferon response. Mechanistically, type I interferon-binding brings the IFNAR1 and IFNAR2 subunits into close proximity with one another, driving their associated Janus kinases (JAKs) (TYK2 bound to IFNAR1 and JAK1 bound to IFNAR2) to cross-phosphorylate one another. The activated kinases phosphorylate specific tyrosine residues on the intracellular domains of IFNAR1 and IFNAR2, forming docking sites for the STAT transcription factors. STAT proteins are then phosphorylated by the JAKs, promoting their translocation into the nucleus to regulate expression of interferon-regulated genes
Subcellular location: Cell membrane; Single-pass membrane protein
InterPro domains:
- IPR015373: Interferon/interleukin receptor domain (domain) [124-225]
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [19-224]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [19-228]
- IPR003961: Fibronectin type III (domain) [6-112]
- IPR050650: Type II Cytokine and Tissue Factor Receptors (family) [7-345]
Sequence:
MEECALLLLLLGAAASTGLSPPQNLGLQTLNTQYVLHWDWPGNQSAVNQSVRFTAQYMSEFRSRRAEHMQKWLTVCEDVEEQRCDFTHAGLFYLGIYLLRVRANTREQASNWTQISFCPDKHAALGPPSSVTLRSVRGVLEMVMADPLSSTNESMKTLVQDMYYLIQYWRQADDTRQAKELRTPNNLVVLPDLARWSVYCVRVQSRYDFENKSSVFSDTHCAQTEGQTAVWLILLYFLLALVLVFLLVLLLFLCSYRTFQTFKSVCRPSAQLPAHIQELWLSDADTPQILLSKECVCEHMDVALVCAVDTHIPEEPQDSGGSSSDTHSSGDSGVYSEEDSATHTHSHSLSLKNTHTHDHTLLLTDTL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0140375 (immune receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0004896 (cytokine receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0072001 (renal system development), GO:0030097 (hemopoiesis), GO:0001822 (kidney development), GO:0048793 (pronephros development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Stromelysin-3 (A0A8M9Q3Z2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted, extracellular space, extracellular matrix
InterPro domains:
- IPR024079: Metallopeptidase, catalytic domain superfamily (homologous_superfamily) [78-272]
- IPR018487: Hemopexin-like repeats (repeat) [289-480]
- IPR018486: Hemopexin, conserved site (conserved_site) [330-440]
- IPR001818: Peptidase M10, metallopeptidase (domain) [113-267]
- IPR021190: Peptidase M10A (family) [84-481]
- IPR000585: Hemopexin-like domain (domain) [289-480]
- IPR036375: Hemopexin-like domain superfamily (homologous_superfamily) [285-482]
- IPR033739: Peptidase M10A, catalytic domain (domain) [113-267]
- IPR006026: Peptidase, metallopeptidase (domain) [110-268]
Sequence:
MRVSGLLACAFALHVLLTARCLPLHGGQGLAKHKESPGLSYIPHLHSEKRRGRVPHPQDTFKPPAWPKEEPHINTPLRNSSRATGPKRCGVPDYPEQRDVHLRQKRYVLFGGRWPKTDLTYKIQRFPWQMREDKVRRIFQEALKVWSDVTPLTFTEVVNQEADIVIDFTRYWHGDNLPFDGPGGILAHAFFPRTHREGDIHFDYDESWTVGNELGTDLLQVAAHEFGHVLGLQHSLVPGAIMSPFYSFSYPLKLSEDDKKGIQYLYGPPVRAQPQIPAETNDIPSAFPPDACHTDFDAVSIIRGELFFFKASYAWRIRDGRLQAGYPALASRHWSGIPQKIDAAYEDKKGNIWFFEGSNYWVFDAEHRIKGPDSLLSLGLRVSNIQAALRVKEHHSQHTYFFKSGNYWRLDPQENRVDTSAPRRIQQDWWGVPEEIDAAFQEASGFVVFISRRQYWKFDPVQRKVLEGYPRYIGADFFGCNMP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008237 (metallopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0048870 (cell motility), GO:0042221 (response to chemical), GO:0050900 (leukocyte migration), GO:0042330 (taxis), GO:0097529 (myeloid leukocyte migration), GO:0006935 (chemotaxis), GO:0030595 (leukocyte chemotaxis), GO:0070887 (cellular response to chemical stimulus), GO:0016477 (cell migration), GO:1905517 (macrophage migration), GO:0060326 (cell chemotaxis), GO:0048246 (macrophage chemotaxis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix)
Protein: Solute carrier family 22 member 3 (Q7T2C0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Mitochondrion membrane. Nucleus outer membrane
InterPro domains:
- IPR004749: Organic cation transport protein/SVOP (family) [13-525]
- IPR036259: MFS transporter superfamily (homologous_superfamily) [115-528]
- IPR005829: Sugar transporter, conserved site (conserved_site) [394-410]
- IPR005828: Major facilitator, sugar transporter-like (family) [151-524]
- IPR020846: Major facilitator superfamily domain (domain) [113-519]
Sequence:
MTTFEEILEEAGTFGRSQIRIFCTFCLVSIPFSFVYVGIVFQGFTPEHWCRDPGVSEIRERCGWSLQDARRATVPLINGSSGASYSQCGRFDVDWNATGLSCENPDGDFNQSQLSVMPMMSCVDGWEYDYVGRQSFVTEFDLVCGDAWYVDMFQATLSIGFLVGSIAIGYLADKYGRMKSFLMTNFFIGVTGILVATSPNYISLLVFRALFGFGVKGGWMVGYVLITELVGVDHRRTVGVTYQLFFSMGILLLPLLAYFITNWRWLQVVFTVPYICFLTYYWFIPESPRWLLTQNKIAEAVEITKSIAKENRKTLSKKIETLKDDNIDSGSTASFMDLFKTAKLRTYTFILSFNWFTSAVVYQGLIMRLGILGGNVYVDFLISGIVELPAAFLILLTIERIGRRLPFATANIVAGAACLITAFIPDSMFWLKSAVACVGRLGITMAFEMVVFVNTELYPTVIRNLGVSVCSTLCDVGGIVAPFLLYRLAVIWLELPLIIFGALAFVAGGLVLLLPETKGVPLPETIDDIEHPNRNKENPQQSQQLENLMTSDVTKNKDVTAV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0007389 (pattern specification process), GO:0009799 (specification of symmetry), GO:0048513 (animal organ development), GO:0003002 (regionalization), GO:0048731 (system development), GO:0009855 (determination of bilateral symmetry), GO:0060972 (left/right pattern formation), GO:0072359 (circulatory system development), GO:0007507 (heart development), GO:0061371 (determination of heart left/right asymmetry), GO:0007368 (determination of left/right symmetry)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Teleost multiple tissue opsin 1b (A0A8N7XJ92)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Multi-pass membrane protein
InterPro domains:
- IPR001760: Opsin (family) [61-294]
- IPR027430: Visual pigments (opsins) retinal binding site (binding_site) [287-303]
- IPR017452: GPCR, rhodopsin-like, 7TM (domain) [55-303]
- IPR050125: G-protein coupled receptor opsins (family) [28-322]
- IPR000276: G protein-coupled receptor, rhodopsin-like (family) [40-311]
- IPR002962: Peropsin (family) [59-289]
Sequence:
MIESNVSRSCEWCAGGGEGTGAHLDENHSDHSLSPTGHLVVAVCLGFIGTFGFLNNTLVLVLFCRYKVLRSPMNCLLISISVSDLLVCVLGTPFSFAASTQGRWLIGRAGCVWYGFINSFLGVVSLISLAVLSYERYCTMMGSTQADSTNYRKVVIGIAFSWIYSMVWTLPPLFGWSCYGPEGPGTTCSVNWAARTPNNVSYIVCLFVFCLILPFIVIVYSYGRLLQAITQVSRINTVVSRKREQRVLFMVVTMVVCYLLCWLPYGIMALLATFGHPGLVTPAASIVPSLLAKSSTVINPIIYIFMNKQFCRCFHALIMCTTPERGSSFKNSSKVTKTLRTVRRANGQNVTFAVASAVHRTPYSDRQKSSSEGEKLPPATGQGTSKPVVSLVAYYNG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0009881 (photoreceptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007186 (G protein-coupled receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0043227 (membrane-bounded organelle), GO:0120025 (plasma membrane bounded cell projection), GO:0005929 (cilium), GO:0097730 (non-motile cilium)
Protein: Syntaxin-16 (A0A8M9QGE3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network
Subcellular location: Golgi apparatus membrane; Single-pass type IV membrane protein
InterPro domains:
- IPR006012: Syntaxin/epimorphin, conserved site (conserved_site) [218-257]
- IPR000727: Target SNARE coiled-coil homology domain (domain) [207-300]
- IPR045242: Syntaxin (family) [66-294]
- IPR010989: SNARE (homologous_superfamily) [57-267]
Sequence:
MATRRLTDAFLLMRNNAIQNRQILAEQEFDELADDRMALVSGISLDPEAAIGVTKRLPPKWVEGVDEIQYEITRIRQKMKELASLHDKHMNRPTLDDSSEEEHAIEITTQEITQMFHRCQRAVTGLQTQSYHCTEQENRLLTNVVSSLAQSLQELSLNFRHTQSGYLKRMKNREERSKHFFDSGPLVEEDEDIALYDRGFTDDQLVLVQQNTVMVEEREREIRQIVQSISDLNEIFRDLAGMVVEQGTVLDRIDFNVEQSCVKTEEGLQQLQKAEQYQKKNRKMLVILILFVIVVVLILILFGTKFS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0035295 (tube development), GO:0009887 (animal organ morphogenesis), GO:0048729 (tissue morphogenesis), GO:0048513 (animal organ development), GO:0009888 (tissue development), GO:0048731 (system development), GO:0035239 (tube morphogenesis), GO:0072001 (renal system development), GO:0060562 (epithelial tube morphogenesis), GO:0002009 (morphogenesis of an epithelium), GO:0060429 (epithelium development), GO:0001822 (kidney development), GO:0072176 (nephric duct development), GO:0060993 (kidney morphogenesis), GO:0072114 (pronephros morphogenesis), GO:0048793 (pronephros development), GO:0072073 (kidney epithelium development), GO:0039022 (pronephric duct development), GO:0072178 (nephric duct morphogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)