lokahq/bioreason-rl huggingface dataset:
Protein: Glutamate dehydrogenase 1, mitochondrial (EC 1.4.1.3) (Q70PJ6)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Function: Not known
InterPro domains:
- IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [150-441]
- IPR006097: Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, dimerisation domain (domain) [2-125]
- IPR033922: NAD(P) binding domain of glutamate dehydrogenase (domain) [147-432]
- IPR006096: Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, C-terminal (domain) [147-438]
- IPR046346: Aminoacid dehydrogenase-like, N-terminal domain superfamily (homologous_superfamily) [2-149]
- IPR014362: Glutamate dehydrogenase (family) [1-441]
- IPR006095: Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase (family) [53-325]
Sequence:
SVSFPIKRDNGEWEVIEGYRAQHSQHRTPCKGGIRYSTEVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINVKNYTDNELEKITRRFTIELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYANTMGHHDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEAAYMSQLGLSPGFTDKTFVIQGFGNVGMHSMRYLHRFGAKCVGVGEMDGNIWNPNGIDPKELEDYKLQHGTIVGFPNSTPYEGSILEADCDILIPAASEKQLTRNNAHKIKAKIIAEGANGPTTPDADKIFLERNIMVIPDMYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGAIPVVPTSEFQARIAGASEKDIVHSGLAYTMERSARQIMRTANKYNLGLDLRTATYVNAIEKVFKVYNEAGLTFT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016638 (oxidoreductase activity, acting on the CH-NH2 group of donors), GO:0016639 (oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor), GO:0004353 (glutamate dehydrogenase [NAD(P)+] activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:0032094 (response to food), GO:0009991 (response to extracellular stimulus), GO:0031667 (response to nutrient levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Nucleoprotein (Nucleocapsid protein) (NC) (Protein N) (Q6Q1R8)
Organism: Human coronavirus NL63 (HCoV-NL63)
Function: Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.
Subcellular location: Virion {ECO:0000255|HAMAP-Rule:MF_04095}. Host endoplasmic reticulum-Golgi intermediate compartment {ECO:0000255|HAMAP-Rule:MF_04095}. Host Golgi apparatus {ECO:0000255|HAMAP-Rule:MF_04095}. Note=Located inside the virion, complexed with the viral RNA. Probably associates with ER-derived membranes where it participates in viral RNA synthesis and virus budding. {ECO:0000255|HAMAP-Rule:MF_04095}.
InterPro domains:
- IPR044344: Nucleocapsid (N) protein, C-terminal domain, coronavirus (domain) [223-337]
- IPR044345: Nucleocapsid (N) protein, N-terminal domain, coronavirus (domain) [17-139]
- IPR042548: Nucleocapsid protein, alphacoronavirus (family) [1-377]
- IPR037195: Nucleocapsid protein, N-terminal (homologous_superfamily) [1-150]
- IPR001218: Nucleocapsid protein, coronavirus (family) [1-376]
- IPR037179: Nucleocapsid protein, C-terminal (homologous_superfamily) [227-334]
Sequence:
MASVNWADDRAARKKFPPPSFYMPLLVSSDKAPYRVIPRNLVPIGKGNKDEQIGYWNVQERWRMRRGQRVDLPPKVHFYYLGTGPHKDLKFRQRSDGVVWVAKEGAKTVNTSLGNRKRNQKPLEPKFSIALPPELSVVEFEDRSNNSSRASSRSSTRNNSRDSSRSTSRQQSRTRSDSNQSSSDLVAAVTLALKNLGFDNQSKSPSSSGTSTPKKPNKPLSQPRADKPSQLKKPRWKRVPTREENVIQCFGPRDFNHNMGDSDLVQNGVDAKGFPQLAELIPNQAALFFDSEVSTDEVGDNVQITYTYKMLVAKDNKNLPKFIEQISAFTKPSSIKEMQSQSSHVAQNTVLNASIPESKPLADDDSAIIEIVNEVLH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0016032 (viral process), GO:0019068 (virion assembly), GO:0019058 (viral life cycle)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0033643 (host cell part), GO:0043657 (host cell), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0030430 (host cell cytoplasm)
Protein: Large ribosomal subunit protein uL22 (60S ribosomal protein L17) (Q54NG2)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Not known
InterPro domains:
- IPR001063: Large ribosomal subunit protein uL22 (family) [17-152]
- IPR036394: Ribosomal protein uL22 superfamily (homologous_superfamily) [4-180]
- IPR005721: Large ribosomal subunit protein uL22, eukaryotic/archaeal (family) [6-177]
Sequence:
MTKPVYSKTPSNPEKSCKSRGSNLRIHFKNTRESAMAIKGMLLTRAKAYLNNVLAHRECIPFRRFKGGVGRTGQAKIFGTSQGRWPKKSVEHILSLLQNAEANAEAKGLNVEKLKIAHVQVQRAQQQRRRTYRAHGRINPYMCSPSTVEFILTEVEKAVPKPAEESAQKKKSVATQEISA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0043933 (protein-containing complex organization), GO:0006996 (organelle organization), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0065003 (protein-containing complex assembly), GO:0042254 (ribosome biogenesis), GO:0022618 (ribonucleoprotein complex assembly), GO:0042273 (ribosomal large subunit biogenesis), GO:0071826 (ribonucleoprotein complex subunit organization), GO:0042255 (ribosome assembly), GO:0140694 (non-membrane-bounded organelle assembly), GO:0000027 (ribosomal large subunit assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix)
Protein: Carboxypeptidase N catalytic chain (CPN) (EC 3.4.17.3) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit) (Q9JJN5)
Organism: Mus musculus (Mouse)
Function: Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation.
Subcellular location: Secreted, extracellular space {ECO:0000269|PubMed:10878383}.
InterPro domains:
- IPR057247: Zinc carboxypeptidases, zinc-binding region 2 (binding_site) [216-226]
- IPR008969: Carboxypeptidase-like, regulatory domain superfamily (homologous_superfamily) [341-425]
- IPR000834: Peptidase M14, carboxypeptidase A (domain) [24-428]
- IPR057246: Zinc carboxypeptidases, zinc-binding region 1 (binding_site) [77-99]
- IPR050753: Peptidase M14 domain-containing protein (family) [19-419]
Sequence:
MPDLPSAFLPLLLLSKFVTPVTFRHHRYDDLVRTLYKVHNQCPDITRLYNIGRSVKGRYLYVLEFSDYPGIHEPLEPEVKYVGNMHGNEVLGRELLLQLSEFLCEEFRNRNQRILRLIQDTRIHILPSMNPDGYEVAAAQGPNMSGYLVGRNNANGVDLNRNFPDLNTYFYYNSKNGGPNHHLPLPDNWKSQVEPETRAVIQWIRSLNFVLSANMHGGAVVANYPYDKSLEHRFRGPHRTSNSPTPDDELFQTLAKVYSYAHGWMHQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPRQEELQREWLGNREALIQFLEQVHQGIKGMVLDENSNNLTGAVISVTGINHDVTSGEHGDYFRLLLPGTYSVTAKAPGYDPKTVTVTVGPAGPTVVDFQLKRSSSQVYPVQRAPGRGQGGRAKQPRTSRKKDPATKRHRGPA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008238 (exopeptidase activity), GO:0004180 (carboxypeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044248 (cellular catabolic process), GO:0019538 (protein metabolic process), GO:0043603 (amide metabolic process), GO:1901575 (organic substance catabolic process), GO:0043170 (macromolecule metabolic process), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0009057 (macromolecule catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0006518 (peptide metabolic process), GO:0043171 (peptide catabolic process), GO:0033993 (response to lipid), GO:0030163 (protein catabolic process), GO:0048545 (response to steroid hormone), GO:0014070 (response to organic cyclic compound), GO:0031960 (response to corticosteroid), GO:0051384 (response to glucocorticoid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Glycine betaine uptake system permease protein YehW (P33359)
Organism: Escherichia coli (strain K12)
Function: Part of an ABC transporter complex involved in low-affinity glycine betaine uptake. Probably responsible for the translocation of the substrate across the membrane.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000255}.
InterPro domains:
- IPR051204: ABC transporter permease/solute-binding domain-containing protein (family) [42-241]
- IPR035906: MetI-like superfamily (homologous_superfamily) [41-239]
- IPR000515: ABC transporter type 1, transmembrane domain MetI-like (domain) [50-239]
Sequence:
MKMLRDPLFWLIALFVALIFWLPYSQPLFAALFPQLPRPVYQQESFAALALAHFWLVGISSLFAVIIGTGAGIAVTRPWGAEFRPLVETIAAVGQTFPPVAVLAIAVPVIGFGLQPAIIALILYGVLPVLQATLAGLGAIDASVTEVAKGMGMSRGQRVRKVELPLAAPVILAGVRTSVIINIGTATIASTVGASTLGTPIIIGLSGFNTAYVIQGALLVALAAIIADRLFERLVQALSQHAK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0071705 (nitrogen compound transport), GO:0015695 (organic cation transport), GO:0015846 (polyamine transport), GO:0015847 (putrescine transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Proliferating cell nuclear antigen (B5X3H8)
Organism: Salmo salar (Atlantic salmon)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU000641}.
InterPro domains:
- IPR046938: DNA clamp superfamily (homologous_superfamily) [1-255]
- IPR000730: Proliferating cell nuclear antigen, PCNA (family) [1-258]
- IPR022648: Proliferating cell nuclear antigen, PCNA, N-terminal (domain) [1-124]
- IPR022649: Proliferating cell nuclear antigen, PCNA, C-terminal (domain) [127-254]
- IPR022659: Proliferating cell nuclear antigen, PCNA, conserved site (conserved_site) [34-79]
Sequence:
MFEARLVQGSILKKVLEALKDLITEACWDVSSSGISLQSMDSSHVSLVQLTLRSDGFDSYRCDRNLAMGVNLSSMSKILKCAGNEDIITLRAEDNADTLALVFETLNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVRMPSGEFARICRDLSQIGDAVMISCAKDGVKFSATGELGTGNVKLSQTSNVDKEEEAVSIEMNEPVQLIFALNYLNFFTKATPLSKTVILSMSADIPLVVEYKIADMGHVKYYLAPKIDEEAS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008134 (transcription factor binding), GO:0140297 (DNA-binding transcription factor binding), GO:0061629 (RNA polymerase II-specific DNA-binding transcription factor binding), GO:0016922 (nuclear receptor binding), GO:0030331 (nuclear estrogen receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0009636 (response to toxic substance)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Mitochondrial fission regulator 1 (Chondrocyte protein with a poly-proline region) (Q99MB2)
Organism: Mus musculus (Mouse)
Function: May play a role in mitochondrial aerobic respiration. May also regulate mitochondrial organization and fission.
Subcellular location: Mitochondrion {ECO:0000250}. Note=May be associated with the inner and the outer mitochondrial membrane. {ECO:0000250}.
InterPro domains:
- IPR007972: Mitochondrial fission regulator 1 (family) [5-320]
Sequence:
MLGWIKCLMRMWFQRVGVSMQSVLWSGKPYGSSRSIVRKIGTNLSLIQCPRVQFQLTSHATEWSPAHSGEDAVASFADVGLVATEEGECSIRLRAEVSSKPPHEDDPPCFEKPPSRHTSFPSLSQDKPSPERTLASEEALQKISALENELAALRAQIAKIVTLQEQQSPSAGCLDSSTSVTVAPPPPPPPPPPPLPLVLHQSTSALDLIKERREQRLSAGKTLATGHPKKPDMPNMLEILKDMNSVKLRSVKRSEKDVKPRPADTDHAAFIAEALKKKFAYRHNSQGETERGIPKPESEATSEPALFGPHILKSTGKMKALIENVPDS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044237 (cellular metabolic process), GO:0016043 (cellular component organization), GO:0006091 (generation of precursor metabolites and energy), GO:0015980 (energy derivation by oxidation of organic compounds), GO:0006996 (organelle organization), GO:0007005 (mitochondrion organization), GO:0045333 (cellular respiration), GO:0048285 (organelle fission), GO:0000266 (mitochondrial fission), GO:0009060 (aerobic respiration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Chromo domain-containing protein cec-4 (Q19972)
Organism: Caenorhabditis elegans
Function: Chromatin anchor protein which binds to methylated lysine residues on histone H3, thereby recruiting heterochromatin to the nuclear periphery, especially in embryonic cells, with a lesser role in differentiated cells. May be required for the correct positioning of chromatin and nucleoli in embryos.
Subcellular location: Nucleus inner membrane {ECO:0000269|PubMed:26607792}. Membrane {ECO:0000305|PubMed:26607792}; Peripheral membrane protein {ECO:0000305|PubMed:26607792}.
InterPro domains:
- IPR000953: Chromo/chromo shadow domain (domain) [86-147]
- IPR023780: Chromo domain (domain) [87-138]
- IPR016197: Chromo-like domain superfamily (homologous_superfamily) [80-142]
- IPR037948: Chromo domain-containing protein cec-4 (family) [1-159]
Sequence:
MAKKTVEGEHGTPKTNFTKKETSKNHDDFKKIIGHKVVEEHYVEYEVELTSGKTITATEFDFKGDDSLLSTYKKKVTKQSDDSSGEYAVERVLAHRKVKGSPLYLVQWKGYPHPVWNSEMWEEDLDNCKDLLAAYKKHQEDLKIAQTPKKTPSKTPKKTPKSLKRRALTPSDDEEEAGPIAPEPKKTPKQSTKKLKRTTSPETNLVEKSKKKAIPDLENHTLDQEKNDVIERVEEIQEDEDDDDEQREEVVTTAPVETKSRWGFGSWKWF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding), GO:0005515 (protein binding), GO:0042393 (histone binding), GO:0140030 (modification-dependent protein binding), GO:0035064 (methylated histone binding), GO:0140034 (methylation-dependent protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0009892 (negative regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0010629 (negative regulation of gene expression), GO:0010468 (regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0031974 (membrane-enclosed lumen), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0043233 (organelle lumen), GO:0005635 (nuclear envelope), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031965 (nuclear membrane), GO:0019866 (organelle inner membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0005637 (nuclear inner membrane), GO:0005634 (nucleus)
Protein: Large ribosomal subunit protein uL4m (54S ribosomal protein yml6, mitochondrial) (O74801)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Not known
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823372}.
InterPro domains:
- IPR002136: Large ribosomal subunit protein uL4 (family) [27-222]
- IPR023574: Large ribosomal subunit protein uL4 domain superfamily (homologous_superfamily) [2-231]
- IPR013005: Large ribosomal subunit protein uL4-like (family) [8-227]
Sequence:
MTAKMLHLVRYKFPSLEPASLFLIPGSFLQERFRRDILHRAVIYEADNDRQGTASSKRRNEITCSGRKLYRQKGTGHARVGDASSPIRRGGAKSHGPKPRDFSTKLQTQVYNLAMRIALSTRFINNELTILENPINLSQPKTRILLEVLKQHKLGHEYGKALFVLNDNYFEDESLKNNNLLLASRQLGYHCSFIPVGEFQVRDALKFGKLFIDSEAMSLIVEKFAQRNTLSDMDQPASLTAYVDANSSSFTKSKPEPSLSL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0019538 (protein metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006412 (translation), GO:0009059 (macromolecule biosynthetic process), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:0006518 (peptide metabolic process), GO:0010467 (gene expression), GO:0140053 (mitochondrial gene expression), GO:0043043 (peptide biosynthetic process), GO:0032543 (mitochondrial translation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Trafficking protein particle complex subunit (Q9VA95)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Endoplasmic reticulum {ECO:0000256|RuleBase:RU366065}. Golgi apparatus, cis-Golgi network {ECO:0000256|RuleBase:RU366065}.
InterPro domains:
- IPR011012: Longin-like domain superfamily (homologous_superfamily) [1-136]
- IPR007233: Trafficking protein particle complex subunit (family) [1-138]
Sequence:
MTIFNLYIFDKFGTLLHYAEWNRTKKSGITREEEAKLTYGMLFSIKSFVSKISPHDPKEGFLYYKTNRYALHYLETPSGLKFVLNTDTTAINVKELLQQLYAKVWVEFVVRDPLWTPGTVVTSELFQSKLDEFVRQSPIFGIRNI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0016192 (vesicle-mediated transport), GO:0048193 (Golgi vesicle transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0099023 (vesicle tethering complex), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0140535 (intracellular protein-containing complex), GO:0005794 (Golgi apparatus), GO:0030008 (TRAPP complex), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:1990071 (TRAPPII protein complex), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)
Protein: UBX domain-containing protein 4 (Q9P7L2)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway.
Subcellular location: Cytoplasm. Nucleus.
InterPro domains:
- IPR021569: TUG ubiquitin-like domain (domain) [7-68]
- IPR001012: UBX domain (domain) [341-390]
- IPR029071: Ubiquitin-like domain superfamily (homologous_superfamily) [7-391]
Sequence:
MATIYACRGFHRVPVKLSPSSTLQEVILSSYKQLGFSDWHNLELLHGDKKVDTSLLLRLSGIINGAKLIVKESATNQSGKSSSSISPQSKKIKVALQLPGAARIIDEASSETSIKQLLERHSLLTKVSHVLINGRNFKSEEFDNPLLLYGIREGSILIRLFPIKAQQSIVSEQAPVSQTFNGDVKEKKNADLMDIESENKKDDIVESFPKYPVDAHKLLEPLPTPIPSLPSTPSSYQNLPSQSLTGESLPTVSNQEKDEGVIEKVAVNNTPSVSSKSPFPKKKSFSSMLAQVKKEKAENNGSDGYDLQPTKSQLELYQSILRKRANQVSSTSLTKSSSPKPLPSSAIVKFDFGNGKSIVHEFSKDDNIETLRAFVASHLSPEESTSFQLTFSNYEALPTTGLIVEHIGRAVVRVHTISDPVYAQR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0006984 (ER-nucleus signaling pathway), GO:0006991 (response to sterol depletion), GO:0033554 (cellular response to stress), GO:0032933 (SREBP signaling pathway), GO:0071501 (cellular response to sterol depletion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)