lokahq/bioreason-rl huggingface dataset:
Protein: SWI/SNF complex subunit SWI3C (AtSWI3C) (Transcription regulatory protein SWI3C) (Q9XI07)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of a multiprotein complex equivalent of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00624}.
InterPro domains:
- IPR032451: SMARCC, C-terminal (domain) [585-658]
- IPR000433: Zinc finger, ZZ-type (domain) [340-394]
- IPR001005: SANT/Myb domain (domain) [399-447]
- IPR007526: SWIRM domain (domain) [176-274]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [175-452]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [182-269]
- IPR017884: SANT domain (domain) [398-449]
Sequence:
MPASEDRRGKWKRKKRGGLSAARKPKQEEEDMEEEDEENNNNNNEEMDDVENADELQQNGGATPDPGLGIGEVVEDSGSRISDFPAVVKRVVIRPHASVMAVVAAERAGLIGETRGQGSLPALENISFGQLQALSTVPADSLDLERSDGSSSAYVISPPPIMDGEGVVKRFGDLVHVLPMHSDWFAPNTVDRLERQVVPQFFSGKSPNHTPESYMEFRNAIVSKYVENPEKTLTISDCQGLVDGVDIEDFARVFRFLDHWGIINYCATAQSHPGPLRDVSDVREDTNGEVNVPSAALTSIDSLIKFDKPNCRHKGGEVYSSLPSLDGDSPDLDIRIREHLCDSHCNHCSRPLPTVYFQSQKKGDILLCCDCFHHGRFVVGHSCLDFVRVDPMKFYGDQDGDNWTDQETLLLLEAVELYNENWVQIADHVGSKSKAQCILHFLRLPVEDGLLDNVEVSGVTNTENPTNGYDHKGTDSNGDLPGYSEQGSDTEIKLPFVKSPNPVMALVAFLASAVGPRVAASCAHESLSVLSEDDRMKSEGMQGKEASLLDGENQQQDGAHKTSSQNGAEAQTPLPQDKVMAAFRAGLSAAATKAKLFADHEEREIQRLSANIVNHQLKRMELKLKQFAEIETLLMKECEQVEKTRQRFSAERARMLSARFGSPGGISPQTNNLQGMSLSTGGNNINSLMHQQHQQQQASATSQPSIIPGFSNNPQVQAQMHFMARQQQQQQQQQQQQQQAFSFGPRLPLNAIQTNAGSTASPNVMFGNNQLNNPAAAGAASINQPSFSHPMVRSSTGSGSGSGLGLN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048583 (regulation of response to stimulus), GO:0080134 (regulation of response to stress), GO:0031347 (regulation of defense response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Inka box actin regulator 2 (E9PR53)
Organism: Homo sapiens (Human)
Function: Not known
InterPro domains:
- IPR039201: PAK4-inhibitor inka (family) [3-102]
Sequence:
MTMESREMDCYLRRLKQELMSMKEVGDGLQDQMNCMMGALQELKLLQVQTALEQLEISGGGPVPGSPEGPRTQCEHPCWEGGRGPARPTVCSPSSQPSLEQPEPTSGAFPIRCS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009887 (animal organ morphogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0090596 (sensory organ morphogenesis), GO:0022008 (neurogenesis), GO:0007399 (nervous system development), GO:0048880 (sensory system development), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0007423 (sensory organ development), GO:0042461 (photoreceptor cell development), GO:0046530 (photoreceptor cell differentiation), GO:0048592 (eye morphogenesis), GO:0001654 (eye development), GO:0150063 (visual system development), GO:0048699 (generation of neurons), GO:0001754 (eye photoreceptor cell differentiation), GO:0042462 (eye photoreceptor cell development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Small ribosomal subunit protein uS7 (30S ribosomal protein S7) (P02359)
Organism: Escherichia coli (strain K12)
Function: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, where it has been shown to contact mRNA. Has been shown to contact tRNA in both the P and E sites; it probably blocks exit of the E site tRNA.
InterPro domains:
- IPR023798: Small ribosomal subunit protein uS7 domain (domain) [2-149]
- IPR005717: Small ribosomal subunit protein uS7, bacterial/organellar-type (family) [1-156]
- IPR036823: Small ribosomal subunit protein uS7 domain superfamily (homologous_superfamily) [1-155]
- IPR020606: Small ribosomal subunit protein uS7, conserved site (conserved_site) [20-46]
- IPR000235: Small ribosomal subunit protein uS7 (family) [3-157]
Sequence:
MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVYSALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAFAHYRWLSLRSFSHQAGASSKQPALGYLN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0005488 (binding), GO:0005515 (protein binding), GO:0003735 (structural constituent of ribosome)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0019538 (protein metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006412 (translation), GO:0009059 (macromolecule biosynthetic process), GO:0006518 (peptide metabolic process), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:0010467 (gene expression), GO:0043043 (peptide biosynthetic process), GO:0002181 (cytoplasmic translation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0044391 (ribosomal subunit), GO:0043229 (intracellular organelle), GO:0022626 (cytosolic ribosome), GO:0043228 (non-membrane-bounded organelle), GO:0022627 (cytosolic small ribosomal subunit), GO:0015935 (small ribosomal subunit), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005840 (ribosome)
Protein: Zinc finger CCHC domain-containing protein 7 (TRAMP-like complex RNA-binding factor ZCCHC7) (Q8N3Z6)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:21855801}.
InterPro domains:
- IPR051644: TRAMP complex component and AT-rich DNA-binding protein (family) [2-519]
- IPR001878: Zinc finger, CCHC-type (domain) [242-365]
- IPR036875: Zinc finger, CCHC-type superfamily (homologous_superfamily) [233-281]
Sequence:
MMFGGYETIEAYEDDLYRDESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEEHEEKNSGNSESSSSKPNQKKLIVLSDSEVIQLSDGSEVITLSDEDSIYRCKGKNVRVQAQENAHGLSSSLQSNELVDKKCKSDIEKPKSEERSGVIREVMIIEVSSSEEEESTISEGDNVESWMLLGCEVDDKDDDILLNLVGCENSVTEGEDGINWSISDKDIEAQIANNRTPGRWTQRYYSANKNIICRNCDKRGHLSKNCPLPRKVRRCFLCSRRGHLLYSCPAPLCEYCPVPKMLDHSCLFRHSWDKQCDRCHMLGHYTDACTEIWRQYHLTTKPGPPKKPKTPSRPSALAYCYHCAQKGHYGHECPEREVYDPSPVSPFICYYDDKYEIQEREKRLKQKIKVLKKNGVIPEPSKLPYIKAANENPHHDIRKGRASWKSNRWPQENKETQKEMKNKNRNWEKHRKADRHREVDEDFPRGPKTYSSPGSFKTQKPSKPFHRSSHYHTSREDKSPKEGKRGKQKKKERCWEDDDNDNLFLIKQRKKKS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0019787 (ubiquitin-like protein transferase activity), GO:0003723 (RNA binding), GO:0004842 (ubiquitin-protein transferase activity), GO:0061659 (ubiquitin-like protein ligase activity), GO:0061630 (ubiquitin protein ligase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0033554 (cellular response to stress), GO:0006974 (cellular response to DNA damage stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005634 (nucleus)
Protein: Actin maturation protease (EC 3.4.11.-) (Actin aminopeptidase ACTMAP) (Q5BKX5)
Organism: Homo sapiens (Human)
Function: Actin maturation protease that specifically mediates the cleavage of immature acetylated N-terminal actin, thereby contributing to actin maturation. Cleaves N-terminal acetylated methionine of immature cytoplasmic beta- and gamma-actins ACTB and ACTG1 after translation. Cleaves N-terminal acetylated cysteine of muscle alpha-actins ACTA1, ACTC1 and ACTA2 after canonical removal of N-terminal methionine (By similarity).
Subcellular location: Cytoplasm {ECO:0000305|PubMed:36173861}.
InterPro domains:
- IPR040043: Actin maturation protease (family) [52-350]
Sequence:
MTSPCSPPLKPPISPPKTPVPQASSIPSPPLPPSPLDFSALPSPPWSQQTPVPPPLPLPPPPAATGPAPRHVFGLEKSQLLKEAFDKAGPVPKGREDVKRLLKLHKDRFRGDLRWILFCADLPSLIQEGPQCGLVALWMAGTLLSPPSGVPLERLIRVATERGYTAQGEMFSVADMGRLAQEVLGCQAKLLSGGLGGPNRDLVLQHLVTGHPLLIPYDEDFNHEPCQRKGHKAHWAVSAGVLLGVRAVPSLGYTEDPELPGLFHPVLGTPCQPPSLPEEGSPGAVYLLSKQGKSWHYQLWDYDQVRESNLQLTDFSPSRATDGRVYVVPVGGVRAGLCGQALLLTPQDCSH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0008233 (peptidase activity), GO:0008238 (exopeptidase activity), GO:0004177 (aminopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0036211 (protein modification process), GO:0051604 (protein maturation), GO:0043412 (macromolecule modification), GO:0006508 (proteolysis), GO:0010467 (gene expression), GO:0016485 (protein processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0012505 (endomembrane system), GO:0043233 (organelle lumen), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005788 (endoplasmic reticulum lumen), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen)
Protein: Testis-specific gamma-tubulin ring protein 128 (Q8IRA1)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
InterPro domains:
- IPR041470: Gamma tubulin complex component protein, N-terminal (domain) [385-539]
Sequence:
MQEDERQKVIERNLPHLVSVLLGSPIDDKKNDNGQVSVEPATFDKCLTYARCHIADPNVVDCDPDAVWDTMNQFLERFRIENLSVFGDTFNQLANVILNHPICMNHKQRNIHWRLLDFVLSVNYKTFVSIRRNLPEMEQKRKNILEALQMATESSQVDPKDKNNTKCVADTEDQLIHKKSQKPKSPRKKLTPDQIQRLCDEIRDLTSSKYGSLHTVRSQIPMEQSKPLDTSDYNYSRELNLGKVAVKENFTIKGAKMELELNVVQNKPSAEKPALVDFFKNESDMLYRIQTNWWQVDISVYNQAHILASNFCQGYADILIFQLWESQASIRKLSEEHQLLSELIVLFFASANCRSFKILNDNWEFRADEPLTCALKQLQEGPHLGEIIKSLKQMRHLRELIETYAVKGIRYDRLKTLTFFSVALRQLLRPVIEFLVHFERRLTSGLEPATLQHFIETSRGHLETIKLLYELSQNKNQELHSLRSLKTLDTLFTKSSQKTQPKLLRSLSASLLLHTVRAYCKFLDNWWSTGDFADYHEEFPFEKIVTDERTEYVLRKSLMQTELQNSELFRIIQRHLLESSDGVAILYDSRTISEFHTLHGIEPEIRLHNSLIDAVIGEIAPYQIKAIEASHYVPDILQQLQSTDHDGIRRLFYSFHMETRPDPRKPAGHSINELLRNFLTCADYTPITEIISQEFQRLLNRRTRLVNSYISGLLQEFQGYKVVRHLRSVFLLWNYDHFRSEFEFFFEFLRRKHLVEATNKLKHIVLCQDFTLGHMFKVCVTEAHPEFICLRVRNDTLLNRIISQQQMDMMNSCFRLLLNLNFSHYRLNHLPPFHYCKYERLFKALRSIQISLISVFEEHLSHPCKLFRKMQNLDSYNSELNEFTSLTQLRRNQEIFGLHIRKYLLEEQFACSLPEILTLSKVFCLRWETTRALVDEYRSQKATSTFERRYKLLRLNYLLETVKKCKAIGCLLGHI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0015631 (tubulin binding), GO:0043015 (gamma-tubulin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007049 (cell cycle), GO:0000278 (mitotic cell cycle)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000930 (gamma-tubulin complex), GO:0005813 (centrosome), GO:0043229 (intracellular organelle), GO:0000931 (gamma-tubulin ring complex), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015630 (microtubule cytoskeleton)
Protein: Glycine betaine/proline betaine transport system ATP-binding protein ProV (P14175)
Organism: Escherichia coli (strain K12)
Function: Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Probably responsible for energy coupling to the transport system (Probable).
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:16079137}; Peripheral membrane protein {ECO:0000269|PubMed:16079137}.
InterPro domains:
- IPR017871: ABC transporter-like, conserved site (conserved_site) [165-179]
- IPR003593: AAA+ ATPase domain (domain) [53-242]
- IPR046342: CBS domain superfamily (homologous_superfamily) [276-395]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [33-289]
- IPR003439: ABC transporter-like, ATP-binding domain (domain) [29-265]
- IPR000644: CBS domain (domain) [343-400]
- IPR051921: ABC transporter osmolyte uptake ATP-binding protein (family) [1-398]
- IPR005892: Glycine betaine/proline betaine transport system ATP-binding protein ProV-like (family) [36-394]
Sequence:
MAIKLEIKNLYKIFGEHPQRAFKYIEQGLSKEQILEKTGLSLGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREVRRKKIAMVFQSFALMPHMTVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFFRGVDISQVFSAKDIARRTPNGLIRKTPGFGPRSALKLLQDEDREYGYVIERGNKFVGAVSIDSLKTALTQQQGLDAALIDAPLAVDAQTPLSELLSHVGQAPCAVPVVDEDQQYVGIISKGMLLRALDREGVNNG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0005315 (inorganic phosphate transmembrane transporter activity), GO:0015291 (secondary active transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0033554 (cellular response to stress), GO:0006974 (cellular response to DNA damage stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:1990351 (transporter complex), GO:0098797 (plasma membrane protein complex), GO:1902495 (transmembrane transporter complex), GO:0005886 (plasma membrane), GO:0098533 (ATPase dependent transmembrane transport complex), GO:0043190 (ATP-binding cassette (ABC) transporter complex)
Protein: Putative S-adenosyl-L-methionine-dependent methyltransferase Rv0281 (EC 2.1.1.-) (P9WFI9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
InterPro domains:
- IPR011610: S-adenosyl-L-methionine-dependent methyltransferase ML2640-like (family) [16-279]
- IPR029063: S-adenosyl-L-methionine-dependent methyltransferase superfamily (homologous_superfamily) [1-302]
- IPR007213: Methyltransferase Ppm1/Ppm2/Tcmp (family) [18-198]
Sequence:
MRTEGDSWDITTSVGSTALFVATARALEAQKSDPLVVDPYAEAFCRAVGGSWADVLDGKLPDHKLKSTDFGEHFVNFQGARTKYFDEYFRRAAAAGARQVVILAAGLDSRAYRLPWPDGTTVFELDRPQVLDFKREVLASHGAQPRALRREIAVDLRDDWPQALRDSGFDAAAPSAWIAEGLLIYLPATAQERLFTGIDALAGRRSHVAVEDGAPMGPDEYAAKVEEERAAIAEGAEEHPFFQLVYNERCAPAAEWFGERGWTAVATLLNDYLEAVGRPVPGPESEAGPMFARNTLVSAARV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0016741 (transferase activity, transferring one-carbon groups), GO:0008168 (methyltransferase activity), GO:0008757 (S-adenosylmethionine-dependent methyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response), GO:0052553 (modulation by symbiont of host immune response), GO:0052559 (induction by symbiont of host immune response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: UBX domain-containing protein (Q580U3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
InterPro domains:
- IPR036249: Thioredoxin-like superfamily (homologous_superfamily) [90-236]
Sequence:
MAMCDCSETVAISLLSEANFDVDYAYHLHMSRTQGADESVTSLHGTSPQGEAPHLQEPELPHASYVVNRLDGGGGYVGGNYPHERDFLLDEVESEQDLLDSVFPIPAFVHRSPEPFDTFCTDSLNRDQWVILSFVLNDFTGFCVNRDIWRSEDLLEVLSMFSIYQTTADVGEGPGLAHGYRLDVEKDIPTLLIINPITRVKETRIPINVHEATIESYEVKNALLTFVGEKGSPNQWEECRLRGTYENASPVLHTENSREYVDVEETSIPFSEPEAGRRDEANEGVVAQPPQILAVDISPYEVPAEVGSAFTLRCRLPKEQLTLRLKPEMPVLLLLKYLSTRLYFSQSTAFPGGVPNCSLRVGFPPKDLIVEDGEVQLGTCPGLRSGDTVVLHIH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010468 (regulation of gene expression), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Keratin, type I cytoskeletal 23 (Cytokeratin-23) (CK-23) (Keratin-23) (K23) (Q9C075)
Organism: Homo sapiens (Human)
Function: Not known
InterPro domains:
- IPR018039: Intermediate filament protein, conserved site (conserved_site) [368-376]
- IPR002957: Keratin, type I (family) [34-408]
- IPR039008: Intermediate filament, rod domain (domain) [71-382]
Sequence:
MNSGHSFSQTPSASFHGAGGGWGRPRSFPRAPTVHGGAGGARISLSFTTRSCPPPGGSWGSGRSSPLLGGNGKATMQNLNDRLASYLEKVRALEEANMKLESRILKWHQQRDPGSKKDYSQYEENITHLQEQIVDGKMTNAQIILLIDNARMAVDDFNLKYENEHSFKKDLEIEVEGLRRTLDNLTIVTTDLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFNVNVKVDTGPREDLIKVLEDMRQEYELIIKKKHRDLDTWYKEQSAAMSQEAASPATVQSRQGDIHELKRTFQALEIDLQTQYSTKSALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRHELERQNNEYQVLLGIKTHLEKEITTYRRLLEGESEGTREESKSSMKVSATPKIKAITQETINGRLVLCQVNEIQKHA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048729 (tissue morphogenesis), GO:0009888 (tissue development), GO:0048731 (system development), GO:0061303 (cornea development in camera-type eye), GO:0048513 (animal organ development), GO:0002009 (morphogenesis of an epithelium), GO:0060429 (epithelium development), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0001654 (eye development), GO:0150063 (visual system development), GO:0043010 (camera-type eye development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005615 (extracellular space), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0005576 (extracellular region), GO:0070062 (extracellular exosome), GO:0043227 (membrane-bounded organelle), GO:0043230 (extracellular organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:1903561 (extracellular vesicle)