lokahq/bioreason-rl huggingface dataset:
Protein: Killer cell lectin-like receptor subfamily F member 2 (Lectin-like receptor F2) (Activating coreceptor NKp65) (D3W0D1)
Organism: Homo sapiens (Human)
Function: C-type lectin-like receptor involved in natural killer cell mediated cytotoxicity and cytokine secretion in keratinocytes via its interaction with CLEC2A.
Subcellular location: Cell membrane {ECO:0000269|PubMed:20194751}; Single-pass type II membrane protein {ECO:0000269|PubMed:20194751}.
InterPro domains:
- IPR051379: C-type Lectin Receptor Immune Modulators (family) [1-198]
- IPR016186: C-type lectin-like/link domain superfamily (homologous_superfamily) [76-196]
- IPR016187: C-type lectin fold (homologous_superfamily) [78-196]
- IPR001304: C-type lectin-like (domain) [78-195]
- IPR033992: Natural killer cell receptor-like, C-type lectin-like domain (domain) [78-195]
Sequence:
MENEDGYMTLSFKNRCKSKQKSKDFSLYPQYYCLLLIFGCIVILIFIMTGIDLKFWHKKMDFSQNVNVSSLSGHNYLCPNDWLLNEGKCYWFSTSFKTWKESQRDCTQLQAHLLVIQNLDELEFIQNSLKPGHFGWIGLYVTFQGNLWMWIDEHFLVPELFSVIGPTDDRSCAVITGNWVYSEDCSSTFKGICQRDAILTHNGTSGV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0005488 (binding), GO:0038023 (signaling receptor activity), GO:0005515 (protein binding), GO:0004888 (transmembrane signaling receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007166 (cell surface receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: GON-4-like protein (Q21216)
Organism: Caenorhabditis elegans
Function: Not known
InterPro domains:
- IPR052435: YY1-Associated Transcriptional Regulator (family) [12-1268]
Sequence:
MEDTAEENNESIDDQPSTSTATDPNQTRETEKEKGDDEMFRLLQATDEILENKAKSMNLSSLNVRSILHHLIKYPSTIDVLLGIRENDDLPSVRNMRSRKKPDDSGASSTVNTPKKFGALRIEDRGPKSFLDLEYEEDDEYDDDYIEENDTSTRNKLNAGSEEDEENDDEEEIEDEGEDEDDEEQDELEEDGEHEITGSEACTSGQNDTMHALLFDETSEDVQNEEDYVLNMTLNDTRAESVAPIPTLDNVDDDGFYRDFVTGINRTEKDNDNLEVLDTEDDPDDEDYNVCADDGLNVEDWDETRQDKTTQIPRHELKALMIDTLLAEKEIPLNAFPEEAINGEEHRKSQKVKDAEVYERINTSISSSSESCSLLKDSLATFRPQELQQLNMQLEQHVQLLTQLVVTCHHDVNLSHVRNSSQLMMNELDDIRQQKIYPTVFDVRNLDAAIESCHDINAFDAVDESFLKYAENTEGYGGIALRPEAAVVLSRSNAIRYPALLPSRQPFFIETPIPFLSEEDLMLAVALLQFAHLPRRGEKEMIDRYTAIQQHCLPARSSYKIRTHLKSMRRSDKNPIHQIMQAAEKGVCKLVLPLKSWQESDTPICQWPPASQPGWYRRFQETFNVTEERKILRKHVSTMVLTPVKNKDRQDQEASEATFESGEEGEDDEFVNMGTAPDGRKIIMGREHIEDLVHQLIKQNEISPSKRRKNPTPMKLSTMIQLEEAEKRIADSQKNSCGGQTISALSNVSGDSNVDNNGTHEKELMPSTSSIDSLESINNQETSKFPRPLPMSDQPTLNTSCHITTTTCSVSYEDVDVGTLKKSYVEITASKYETNSNSCFSYPIPPTPGRRSPDDFDDYFMDLESNSLMWPQTPYAVTDENPQTPRGFSASESSEPIDFSSLGKATSLDTEEIVFQSTSCQRPMGYCSDFGEFSNSSSLPEEIPVPSHQRTPQESAIEDDSSMPGLDMVPLYEEDVEECIIEDIEEEEAPIKQGLVNSRPPLRFKKEVKAGITNLAPSRKRTRIEREAMGSVGLDDEQLHDKQKENIMRKVIEDVNQRLFMHTDTYQRFKEAITDENLTDFEKVTRTIIILANHPELLNLVLLNAPPEAVISDLQCDHNYQSYKVAIEMIMDIERYITAAKLKEPSLKGLFRYIQSFLEDKPNMTDEQATKRFYELFGQDRPLWKKLESRFWCLPYKARPRLENYEYIDLTGLETMSKREKRDWNSIPPRFETVDDIDQVMGSVYRASKNEPPSNLVVKCGEFCIRNDDETYTQLEITERLWTRKDDISLLTSYNEALKTIPNFTVSQMPSLISDLSFGEKSIIARLQYLLTELKSLD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0050794 (regulation of cellular process), GO:0003006 (developmental process involved in reproduction), GO:0048522 (positive regulation of cellular process), GO:0051302 (regulation of cell division), GO:0048608 (reproductive structure development), GO:0045137 (development of primary sexual characteristics), GO:0007548 (sex differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0051781 (positive regulation of cell division), GO:0008406 (gonad development), GO:0061458 (reproductive system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus), GO:0043073 (germ cell nucleus)
Protein: Serine/threonine-protein kinase BSK4 (EC 2.7.11.1) (Brassinosteroid-signaling kinase 4) (F4HU55)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable serine/threonine kinase that acts as positive regulator of brassinosteroid (BR) signaling downstream of the receptor kinase BRI1. Functions redundantly with BSK3, BSK6, BSK7 and BSK8.
Subcellular location: Cell membrane {ECO:0000305|PubMed:12912986}; Lipid-anchor {ECO:0000305|PubMed:12912986}.
InterPro domains:
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [29-318]
- IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [372-482]
- IPR045845: Serine/threonine-protein kinase BSK (family) [1-476]
- IPR001245: Serine-threonine/tyrosine-protein kinase, catalytic domain (domain) [63-307]
- IPR000719: Protein kinase domain (domain) [56-322]
Sequence:
MGGQSSKIGTCCSHKTTALEAPDVENKENGEVNGVHSFREYSLEQLKIATSCFALENVVSEHGETAPNVVYQGKLENHMKIAIKRFSGTAWPDPRQFLEEARLVGQLRSKRMANLLGYCCEGGERLLVAEFMPNETLAKHLFHWDTEPMKWAMRLRVALYISEALEYCSNNGHTLYHDLNAYRVLFDEECNPRLSTFGLMKNSRDGKSYSTNLAFTPPEYLRTGRITAESVIYSFGTLLLDLLTGKHIPPSHALDLIRDRNLQTLTDSCLEGQFSDSDGTELVRLTSCCLQYEARERPNIKSLVTALISLQKDTEVLSHVLMGLPQSGTFASPPSPFAEACSGKDLTSMVEILEKIGYKDDEDLSFMWTEQMQEAINSKKKGDIAFRRKDFSEAIEFYTQFLDLGMISATVLVRRSQSYLMSNMAKEALDDAMKAQGISPVWYVALYLQSAALSVLGMEKESQIALTEGSILEARKISASTQN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0050794 (regulation of cellular process), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0007165 (signal transduction), GO:0007154 (cell communication), GO:0071495 (cellular response to endogenous stimulus), GO:1901700 (response to oxygen-containing compound), GO:0009755 (hormone-mediated signaling pathway), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0009725 (response to hormone), GO:0048545 (response to steroid hormone), GO:0009741 (response to brassinosteroid), GO:0032870 (cellular response to hormone stimulus), GO:0014070 (response to organic cyclic compound), GO:0071310 (cellular response to organic substance), GO:0033993 (response to lipid), GO:1901701 (cellular response to oxygen-containing compound), GO:0043401 (steroid hormone mediated signaling pathway), GO:0071367 (cellular response to brassinosteroid stimulus), GO:0071383 (cellular response to steroid hormone stimulus), GO:0071396 (cellular response to lipid), GO:0071407 (cellular response to organic cyclic compound), GO:0009742 (brassinosteroid mediated signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Cathelicidin antimicrobial peptide (Cathelicidin-derived antimicrobial peptide 2) (Q49TU5)
Organism: Salmo salar (Atlantic salmon)
Function: Not known
InterPro domains:
- IPR046350: Cystatin superfamily (homologous_superfamily) [49-112]
Sequence:
MKMKALVRSLLLLAVASLLVRGQTQTETRYEDIITAASNQLLPVEEQAFHPLLNQLEVETLNTEDVDQSEVTVRLSFPLQETLCSKAQGQQGQPCPLKKNGKRMMCSMEVRHPILETGNTLNTDRSDISCEYMEAEDAMPVLSTQKIRTRRGKPSGGSRGSKMGSKDSKGGWRGRPGSGSRPGFGSSIAGASGRDQGGTRNA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097367 (carbohydrate derivative binding), GO:0008289 (lipid binding), GO:0001530 (lipopolysaccharide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0002376 (immune system process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0009893 (positive regulation of metabolic process), GO:0051239 (regulation of multicellular organismal process), GO:0006950 (response to stress), GO:0019222 (regulation of metabolic process), GO:0051707 (response to other organism), GO:0006955 (immune response), GO:0009607 (response to biotic stimulus), GO:0051240 (positive regulation of multicellular organismal process), GO:0006952 (defense response), GO:0060255 (regulation of macromolecule metabolic process), GO:0001819 (positive regulation of cytokine production), GO:0043207 (response to external biotic stimulus), GO:0001817 (regulation of cytokine production), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0045087 (innate immune response), GO:0098542 (defense response to other organism), GO:0010628 (positive regulation of gene expression), GO:0032677 (regulation of interleukin-8 production), GO:0032757 (positive regulation of interleukin-8 production), GO:0010468 (regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Urea transporter DVU1160 (dvUT) (Q72CX3)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Function: Urea channel that facilitates transmembrane urea transport down a concentration gradient.
Subcellular location: Cell membrane {ECO:0000269|PubMed:19865084}; Multi-pass membrane protein {ECO:0000269|PubMed:19865084}.
InterPro domains:
- IPR029020: Ammonium/urea transporter (homologous_superfamily) [1-337]
- IPR004937: Urea transporter (family) [1-337]
Sequence:
MFGEQLLKNPLIEFCDSVCRGCGQVMFQNNTVTGLLFFAGIFYNSTTLGVCAVLGTAASTLTAQLLGVDKPLVRAGLFGFNGTLAGIALPFFFNYEPAMLGYVALNGAFTTIIMASLLNFLGKWGVPALTAPFVLATWLLMFGVYKLSLFHPGALIAPALPSVAGLADMGTVTGRTFMEGLFKGVGEVMFQDNIVTGVIFVVAILVNSRISALFAVIGSLVGLCTALIMHSPETPVRLGLYGFNSVLCGIAMGGIFFYLNIRTFLYALGCMVLGAIATGAFSVLLSPIGMPALTWPFIVVTWLFLFAGSMFRNIAQVPTEKAGTPEDNLRSLAIGSR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0045184 (establishment of protein localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0071705 (nitrogen compound transport), GO:0008104 (protein localization), GO:0015031 (protein transport), GO:0042886 (amide transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Core gene UL37 family protein (ORF 63) (ORF63) (Q76RF5)
Organism: Human herpesvirus 8 (HHV-8) (Kaposi's sarcoma-associated herpesvirus)
Function: Not known
InterPro domains:
- IPR034738: Inner tegument protein (family) [7-928]
- IPR007611: Herpesvirus tegument protein U30 (family) [7-896]
Sequence:
MDGTDALEKLTKGLSGGGGSLHQTKLLMEFQLRGLPVPALLNSSTTEQFLNTVAQLPTDLSKFIRDYRVFALVRAAYFLEPPSSIDPLEAARALGRLVDILSSQPPQNTAPAQPPTSDDTLNNCTLLKLLAHYADQIAGFKTPALPPVPPGIIGLFTCVEQMYHACFQKYWAAALPPMWILTYDPPTSPLQDWLIVAYGNKEGLLLPSGIPSEEVLAKTLVTEHHELFVSRSNSTETAVTMPVSKERALAIYRVFAKGEVVAENTPILAFTDVELSTLKPHYLFIYDFIIEALCKSYTYSCTQARLESFLSRGIDFMTDLGQYLDTATSGKQQLTHSQIKEIKYRLLSCGLSASACDVFRTVIMTLPYRPTPNLANLSTFMGMVHQLTMFGHYFYRCLGSYSPTGLAFTELQKILTRASAEQTERNPWRHPGISDIPLRWKISRALAFFVPPAPINTLQRVYAALPSQLMRAIFEISVKTTWGGAVPANLARDIDTGPNTQHISSTPPPTLKDVETYCQGLRVGDTEYDEDIVRSPLFADAFTKSHLLPILREVLENRLQKNRALFQIRWLIIFAAEAATGLIPARRPLARAYFHIMDILEERHSQDALYNLLDCIQELFTHIRQAVPDAQCPHAFLQSLFVFQFRPFVLKHQQGVTLFLDGLQTSLPPVISLANLGDKLCRLEFEYDSEGDFVRVPVAPPEQPPHVHLSHFKKTIQTIEQATREATVAMTTIAKPIYPAYIRLLQRLEYLNRLNHHILRIPFPQDALSELQETYLAAFARLTKLAADAANTCSYSLTKYFGVLFQHQLVPTAIVKKLLHFDEAKDTTEAFLQSLAQPVVQGQRQGAAGGSGVLTQKELELLNKINPQFTDAQANIPPSIKRSYSNKYDVPEVSVDWETYSRSAFEAPDDELRFVPLTLAGLRKLFVE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0016032 (viral process), GO:0019058 (viral life cycle)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043657 (host cell), GO:0033643 (host cell part), GO:0043227 (membrane-bounded organelle), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0033647 (host intracellular organelle), GO:0030430 (host cell cytoplasm), GO:0033648 (host intracellular membrane-bounded organelle)
Protein: ATP sulfurylase 1, chloroplastic (AtPS1) (EC 2.7.7.4) (Q9LIK9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mediates selenate (Se) reduction, and promotes Se and sulfur (S) uptake and assimilation.
Subcellular location: Plastid, chloroplast stroma {ECO:0000269|PubMed:18431481, ECO:0000269|PubMed:8058839}.
InterPro domains:
- IPR002650: Sulphate adenylyltransferase (family) [53-445]
- IPR024951: Sulphate adenylyltransferase catalytic domain (domain) [223-444]
- IPR025980: ATP-sulfurylase PUA-like domain (domain) [51-213]
- IPR014729: Rossmann-like alpha/beta/alpha sandwich fold (homologous_superfamily) [218-451]
- IPR015947: PUA-like superfamily (homologous_superfamily) [51-219]
Sequence:
MASMAAVLSKTPFLSQPLTKSSPNSDLPFAAVSFPSKSLRRRVGSIRAGLIAPDGGKLVELIVEEPKRREKKHEAADLPRVELTAIDLQWMHVLSEGWASPLGGFMRESEFLQTLHFNSLRLDDGSVVNMSVPIVLAIDDEQKARIGESTRVALFNSDGNPVAILSDIEIYKHPKEERIARTWGTTAPGLPYVDEAITNAGNWLIGGDLEVLEPVKYNDGLDRFRLSPAELRKELEKRNADAVFAFQLRNPVHNGHALLMTDTRRRLLEMGYKNPILLLHPLGGFTKADDVPLDWRMKQHEKVLEDGVLDPETTVVSIFPSPMHYAGPTEVQWHAKARINAGANFYIVGRDPAGMGHPVEKRDLYDADHGKKVLSMAPGLERLNILPFRVAAYDKTQGKMAFFDPSRPQDFLFISGTKMRTLAKNNENPPDGFMCPGGWKVLVDYYESLTPAGNGRLPEVVPV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016779 (nucleotidyltransferase activity), GO:0070566 (adenylyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006790 (sulfur compound metabolic process), GO:0000103 (sulfate assimilation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009532 (plastid stroma), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009570 (chloroplast stroma), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Perilipin 4 (A0A0J9YXN7)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Lipid droplet {ECO:0000256|ARBA:ARBA00004502}.
InterPro domains:
- IPR004279: Perilipin (family) [1157-1366]
Sequence:
MSAPDEGRRDPPKPKGKTLGSFFGSLPGFSSARNLVANAHSSARARPAADPTGAPAAEAAQPQAQVAAHPEQTAPWTEKELQPSEKQMVSGAKDLVCSKMSRAKDAVSSGVASVVDVAKGVVQGGLDTTRSALTGTKEVVSSGVTGAMDMAKGAVQGGLDTSKAVLTGTKDTVSTGLTGAVNVAKGTVQAGVDTTKTVLTGTKDTVTTGVMGAVNLAKGTVQTGVETSKAVLTGTKDAVSTGLTGAVNVARGSIQTGVDTSKTVLTGTKDTVCSGVTGAMNVAKGTIQTGVDTSKTVLTGTKDTVCSGVTGAMNVAKGTIQTGVDTSKTVLTGTKDTVCSGVTGAMNVAKGTIQTGVDTTKTVLTGTKNTVCSGVTGAVNLAKEAIQGGLDTTKSMVMGTKDTMSTGLTGAANVAKGAMQTGLNTTQNIATGTKDTVCSGVTGAMNLARGTIQTGVDTTKIVLTGTKDTVCSGVTGAANVAKGAVQGGLDTTKSVLTGTKDAVSTGLTGAVNVAKGTVQTGVDTTKTVLTGTKDTVCSGVTSAVNVAKGAVQGGLDTTKSVVIGTKDTMSTGLTGAANVAKGAVQTGVDTAKTVLTGTKDTVTTGLVGAVNVAKGTVQTGMDTTKTVLTGTKDTIYSGVTSAVNVAKGAVQTGLKTTQNIATGTKNTFGSGVTSAVNVAKGAAQTGVDTAKTVLTGTKDTVTTGLMGAVNVAKGTVQTSVDTTKTVLTGTKDTVCSGVTGAANVAKGAIQGGLDTTKSVLTGTKDAVSTGLTGAVKLAKGTVQTGMDTTKTVLTGTKDAVCSGVTGAANVAKGAVQMGVDTAKTVLTGTKDTVCSGVTGAANVAKGAVQTGLKTTQNIATGTKNTLGSGVTGAAKVAKGAVQGGLDTTKSVLTGTKDAVSTGLTGAVNLAKGTVQTGVDTSKTVLTGTKDTVCSGVTGAVNVAKGTVQTGVDTAKTVLSGAKDAVTTGVTGAVNVAKGTVQTGVDASKAVLMGTKDTVFSGVTGAMSMAKGAVQGGLDTTKTVLTGTKDAVSAGLMGSGNVATGATHTGLSTFQNWLPSTPATSWGGLTSSRTTDNGGEQTALSPQEAPFSGISTPPDVLSVGPEPAWEAAATTKGLATDVATFTQGAAPGREDTGLLATTHGPEEAPRLAMLQNELEGLGDIFHPMNAEEQAQLAASQPGPKVLSAEQGSYFVRLGDLGPSFRQRAFEHAVSHLQHGQFQARDTLAQLQDCFRLIEKAQQAPEGQPRLDQGSGASAEDAAVQEERDAGVLSRVCGLLRQLHTAYSGLVSSLQGLPAELQQPVGRARHSLCELYGIVASAGSVEELPAERLVQSREGVHQAWQGLEQLLEGLQHNPPLSWLVGPFALPAGGQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0043229 (intracellular organelle), GO:0005886 (plasma membrane), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005811 (lipid droplet)
Protein: Glycine hydroxymethyltransferase (Serine methylase) (G3V4W5)
Organism: Homo sapiens (Human)
Function: Not known
InterPro domains:
- IPR015421: Pyridoxal phosphate-dependent transferase, major domain (homologous_superfamily) [78-237]
- IPR039429: Serine hydroxymethyltransferase-like domain (domain) [49-198]
- IPR049943: Serine hydroxymethyltransferase-like (family) [35-198]
- IPR015424: Pyridoxal phosphate-dependent transferase (homologous_superfamily) [45-237]
Sequence:
MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0005515 (protein binding), GO:0016829 (lyase activity), GO:0042802 (identical protein binding), GO:0016830 (carbon-carbon lyase activity), GO:0016831 (carboxy-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006520 (amino acid metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006082 (organic acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:1901605 (alpha-amino acid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0009069 (serine family amino acid metabolic process), GO:0006544 (glycine metabolic process), GO:0006563 (L-serine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015630 (microtubule cytoskeleton)
Protein: HIT family protein (Q72BI4)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Function: Not known
InterPro domains:
- IPR039383: FHIT family (family) [29-154]
- IPR011146: HIT-like domain (domain) [30-140]
- IPR052908: AP-4-A phosphorylase (family) [9-167]
- IPR036265: HIT-like superfamily (homologous_superfamily) [3-170]
Sequence:
MAIRGFAFMETLWAPWRIDYILGPKPDSCVFCLPEHTGEDEARLILYRGRYNFVIMNKFPYNNGHLMVTPYRHVMDLAALAPEEAHECMDLIQSCVRILKGRFNPQGINVGLNLGEAAGAGIREHLHFHLVPRWNGDSSFMAVMNETRVIPEHLSSTYKALKPHFDRLAADGDA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0044248 (cellular catabolic process), GO:0044248 (cellular catabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901575 (organic substance catabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0034655 (nucleobase-containing compound catabolic process), GO:0044270 (cellular nitrogen compound catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:1901136 (carbohydrate derivative catabolic process), GO:0019439 (aromatic compound catabolic process), GO:1901361 (organic cyclic compound catabolic process), GO:0046700 (heterocycle catabolic process), GO:1901657 (glycosyl compound metabolic process), GO:0034656 (nucleobase-containing small molecule catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)