Protein: Phytoene synthase 3, chloroplastic (OsPSY3) (EC 2.5.1.32) (B6UV92)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Catalyzes the conversion of geranylgeranyl diphosphate to phytoene. Mediates the first committed step in carotenoid biosynthesis. May play a role in regulating carotenoid flux in response to abiotic stress in roots. May control flux to carotenoid precursors that are required for abiotic stress-induced abscisic acid (ABA) formation in roots.
Subcellular location: Plastid, chloroplast membrane {ECO:0000269|PubMed:18326788}; Peripheral membrane protein {ECO:0000305}. Plastid, chloroplast, plastoglobule {ECO:0000269|PubMed:23023170}.
InterPro domains:
- IPR044843: Trans-isoprenyl diphosphate synthases, bacterial-type (family) [146-427]
- IPR002060: Squalene/phytoene synthase (family) [146-427]
- IPR033904: Trans-isoprenyl diphosphate synthases, head-to-head (domain) [150-417]
- IPR008949: Isoprenoid synthase domain superfamily (homologous_superfamily) [140-431]
- IPR019845: Squalene/phytoene synthase, conserved site (conserved_site) [303-328]
Sequence:
MMSTTTTSSAAGSPVCARRRQRVFVDVPRRRATSLARVEYAKMAPPPPPPCSVRAAGSNPIGCLEVAEPWSGAAPPPLPPLPGHLHVAAPAAEDDDDALAAAAAAVPSEQRVHDVVLKQAALAAAAPEMRRPAQLAERERVAGGLNAAFDRCGEVCKEYAKTFYLATQLMTPERRRAIWAIYVWCRRTDELVDGPNASHMSALALDRWESRLDDIFAGRPYDMLDAALSHTVATFPVDIQPFRDMIEGMRLDLTKSRYRSFDELYLYCYYVAGTVGLMTVPVMGISPDSRANTETVYKGALALGLANQLTNILRDVGEDARRGRIYLPMDELEMAGLSEDDIFDGRVTDRWRCFMRDQITRARAFFRQAEEGASELNQESRWPVWASLLLYRQILDEIEANDYNNFTKRAYVPKAKKIVALPKAYYRSLMLPSSVRHCSSLTSS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016787 (hydrolase activity), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups), GO:0004659 (prenyltransferase activity), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016462 (pyrophosphatase activity), GO:0004337 (geranyltranstransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0042440 (pigment metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0046148 (pigment biosynthetic process), GO:0016117 (carotenoid biosynthetic process), GO:0006720 (isoprenoid metabolic process), GO:0008299 (isoprenoid biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0006721 (terpenoid metabolic process), GO:0016114 (terpenoid biosynthetic process), GO:0016108 (tetraterpenoid metabolic process), GO:0016109 (tetraterpenoid biosynthetic process), GO:0016116 (carotenoid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009532 (plastid stroma), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0010287 (plastoglobule), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009570 (chloroplast stroma), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle)