lokahq/bioreason-rl huggingface dataset:
Protein: GH27120p (Q7K2L7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
InterPro domains:
- IPR011992: EF-hand domain pair (homologous_superfamily) [29-193]
- IPR051426: Peflin/Sorcin Calcium-Binding (family) [13-197]
- IPR002048: EF-hand domain (domain) [30-159]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [43-122]
Sequence:
MSYGQGYNPYAQPGGGYAPPPGAFPPQNAQVSPQAQQWFSMVDRDRSGKINASELQAALVNGRGDHFSDNACKLMISMFDNDASGTIDIYEFEKLYNYINQWLQVFKTYDQDSSGHIEEQELTQAFTQMGFRFSPEFINFLVKKSDPQGHKEVSVDQFIVLCVQVQRFTEAFRQRDTQQNGTITIGFEDFLTVAIGCSY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023056 (positive regulation of signaling), GO:0048522 (positive regulation of cellular process), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0010647 (positive regulation of cell communication), GO:0010646 (regulation of cell communication), GO:0080134 (regulation of response to stress), GO:0080135 (regulation of cellular response to stress), GO:0009966 (regulation of signal transduction), GO:0070302 (regulation of stress-activated protein kinase signaling cascade), GO:1902533 (positive regulation of intracellular signal transduction), GO:1902531 (regulation of intracellular signal transduction), GO:0043408 (regulation of MAPK cascade), GO:0032872 (regulation of stress-activated MAPK cascade), GO:0043410 (positive regulation of MAPK cascade), GO:0070304 (positive regulation of stress-activated protein kinase signaling cascade), GO:0046328 (regulation of JNK cascade), GO:0032874 (positive regulation of stress-activated MAPK cascade), GO:0046330 (positive regulation of JNK cascade)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Peptidyl-prolyl cis-trans isomerase CYP20-1 (PPIase CYP20-1) (EC 5.2.1.8) (Cyclophilin of 20 kDa 1) (Rotamase CYP20-1) (Rotamase cyclophilin-7) (Q9SP02)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Seems to be involved in root development.
Subcellular location: Endoplasmic reticulum {ECO:0000250}. Secreted {ECO:0000250}.
InterPro domains:
- IPR024936: Cyclophilin-type peptidyl-prolyl cis-trans isomerase (family) [19-203]
- IPR002130: Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain (domain) [38-201]
- IPR020892: Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site (conserved_site) [86-103]
- IPR029000: Cyclophilin-like domain superfamily (homologous_superfamily) [22-203]
Sequence:
MASSVTLLLWSLLLLGTLSAIQAKKSKENLKEITHKVYFDVEIDGKAAGRIVMGLFGKTVPKTVENFRALCTGEKGIGKNGKALHYKGSSFHRIIPSFMLQGGDFTHGNGMGGESIYGEKFADENFKLKHTGPGFLSMANAGQDTNGSQFFITTVTTSWLDGRHVVFGKVVTGMDVVYKVEAEGNQSGTPKSKVVIVDSGELPL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016853 (isomerase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0016859 (cis-trans isomerase activity), GO:0003755 (peptidyl-prolyl cis-trans isomerase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0001101 (response to acid chemical), GO:1901700 (response to oxygen-containing compound), GO:0009414 (response to water deprivation), GO:0010035 (response to inorganic substance), GO:0009415 (response to water), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:1902074 (response to salt), GO:0097305 (response to alcohol), GO:0009737 (response to abscisic acid), GO:0033993 (response to lipid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0005794 (Golgi apparatus), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0098791 (Golgi apparatus subcompartment), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0005802 (trans-Golgi network), GO:0005797 (Golgi medial cisterna), GO:0097708 (intracellular vesicle)
Protein: Pyruvate decarboxylase (EC 4.1.1.1) (Q6FJA3)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Function: Not known
InterPro domains:
- IPR047213: Pyruvate decarboxylase/indolepyruvate decarboxylase-like, pyrimidine-binding domain (domain) [8-169]
- IPR000399: TPP-binding enzyme, conserved site (conserved_site) [427-446]
- IPR029061: Thiamin diphosphate-binding fold (homologous_superfamily) [4-553]
- IPR029035: DHS-like NAD/FAD-binding domain superfamily (homologous_superfamily) [183-345]
- IPR012001: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (domain) [5-110]
- IPR012000: Thiamine pyrophosphate enzyme, central domain (domain) [201-334]
- IPR047214: Pyruvate decarboxylase/indolepyruvate decarboxylase-like, PP-binding domain (domain) [364-549]
- IPR011766: Thiamine pyrophosphate enzyme, TPP-binding (domain) [405-517]
- IPR012110: Pyruvate decarboxylase/indolepyruvate decarboxylase-like (family) [1-562]
Sequence:
MSEITLGRYLFERLNQVDVKTIFGLPGDFNLSLLDKIYEVEGMRWAGNANELNAAYAADGYARIKGMSCIITTFGVGELSALNGIAGSYAEHVGVLHVVGVPSISSQAKQLLLHHTLGNGDFTVFHRMSANISETTAMVTDIATAPAEIDRCIRTTYITQRPVYLGLPANLVDLKVPAKLLETPIDLSLKPNDPEAETEVVDTVLELIKAAKNPVILADACASRHDVKAETKKLIDATQFPSFVTPMGKGSIDEQHPRFGGVYVGTLSRPEVKEAVESADLILSVGALLSDFNTGSFSYSYKTKNIVEFHSDYIKIRNATFPGVQMKFALQKLLNAVPEAIKGYKPVPVPARVPENKSCDPATPLKQEWMWNQVSKFLQEGDVVITETGTSAFGINQTPFPNNAYGISQVLWGSIGFTTGACLGAAFAAEEIDPKKRVILFIGDGSLQLTVQEISTMIRWGLKPYLFVLNNDGYTIERLIHGEKAGYNDIQNWDHLALLPTFGAKDYENHRVATTGEWDKLTQDKEFNKNSKIRMIEVMLPVMDAPTSLIEQAKLTASINAKQE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016830 (carbon-carbon lyase activity), GO:0016831 (carboxy-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006520 (amino acid metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0006082 (organic acid metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0009081 (branched-chain amino acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0016053 (organic acid biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0046394 (carboxylic acid biosynthetic process), GO:0009082 (branched-chain amino acid biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062039 (biofilm matrix), GO:0062040 (fungal biofilm matrix)
Protein: Innexin inx2 (Innexin-2) (G-Inx2) (Q9XYN1)
Organism: Schistocerca americana (American grasshopper)
Function: Structural components of the gap junctions.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00351}. Cell junction, gap junction.
InterPro domains:
- IPR000990: Innexin (family) [1-359]
Sequence:
MFDVFGSVKGLLKLDSVCIDNNLFRLHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLAVMDTYCWIYSTFTIPNRLNGKIGLEVAHPGVGAHVAGKDEVKYHKYYQWVCFVLFFQAILFYIPRYLWKTWEGGRIKMLVLDLNSPVVNEQSKADRKKLLVDYFATNLHTQNFYAYRFFICEALNFVNVVGQIYFMDLFLDGEFTTYGSDVVRFTEMEPEERSDPMSRVFPKVTKCTFHKYGPSGSVQTFDGLCVLPLNIVNEKIYVFLWFWFVILSVLTGIGLVYRLATAMGPQMRMYLLRARSRLAPQDQIETISNKCQIGDWFVLYQLGKNIDPLIYKELVADLAKKLEGKEIV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015267 (channel activity), GO:0022829 (wide pore channel activity), GO:0005243 (gap junction channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007154 (cell communication), GO:0010644 (cell communication by electrical coupling)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0070161 (anchoring junction), GO:0005886 (plasma membrane), GO:0005911 (cell-cell junction), GO:0005921 (gap junction)
Protein: Alpha/beta-Hydrolases superfamily protein (At1g18360/F15H18_2) (Q8VYJ0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
InterPro domains:
- IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [98-382]
- IPR022742: Serine aminopeptidase, S33 (domain) [128-366]
- IPR051044: Monoacylglycerol and Diacylglycerol Lipase (family) [110-381]
Sequence:
MICSSKGTVVIATRSSFPRLLNRIQNRNDVPISVIATRRSSMSVEAFPMRLKSSQKKRKMNIGCGVSPSSPTTTVVDEEVAIRRKLAMRRVLEDNGGDGSSVRDFSLFTTKRGDTLFTQSWTPVDSAKNRGLVVLLHGLNEHSGRYSDFAKQLNVNGFKVYGIDWIGHGGSDGLHAYVPSLDYAVADLKSFIEKVIAENPGLPCFCIGHSTGGAIILKAMLDAKIEARVSGIVLTSPAVGVQPTYPIFGVIAPFLSFLIPRYQLSAAKKKIMPVSRDPEALLAKYSDPLVYTGFIRARTGNEILRLGAHLLQNLNRIKVPFLVMHGTADTVTDPKGTQKLYNEASSSDKSIKLYDGLLHDLLFEPERETIAGVILDWLNRRV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0016298 (lipase activity), GO:0052689 (carboxylic ester hydrolase activity), GO:0047372 (acylglycerol lipase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0006629 (lipid metabolic process), GO:0006638 (neutral lipid metabolic process), GO:0046486 (glycerolipid metabolic process), GO:0006639 (acylglycerol metabolic process), GO:0006641 (triglyceride metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Heat shock protein sti1 homolog (Q9USI5)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: May play a role in mediating the heat shock response of some HSP70 genes.
Subcellular location: Cytoplasm {ECO:0000250}.
InterPro domains:
- IPR041243: STI1/HOP, DP domain (domain) [139-583]
- IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [1-521]
- IPR019734: Tetratricopeptide repeat (repeat) [2-500]
- IPR006636: Heat shock chaperonin-binding (domain) [139-569]
Sequence:
MAEELKAKGNAAFSKKDYKTAIDYFTQAIGLDERNHILYSNRSACYASEKDYADALKDATKCTELKPDWAKGWSRKGAALHGLGDLDAARSAYEEGLKHDANNAQLLNGLKSVEAAQTQAASGAGGFNPFAKLGSQLSDPKFMEKLASNPETASLLADSAFMAKLQKIQQNPGSIMAELNDPRMMKVIGMLMGIDINMNAGEGAAEEQEKKEEFAPSSSTPSADSAKPETTNPPPQPQASEPMEEDKTAEELEEAATKEALKKKADQEKQIGNENYKKRNFPVAIEQYKKAWDTYKDITYLNNLAAAYFEADQLDDCIKTCEDAIEQGRELRADFKLIAKALGRLGTTYQKRGDLVKAIDYYQRSLTEHRTPDILSRLKDAEKSKELQDREAYIDPDKAEESRVKGNELFKSGDFANAIKEYTEMTKRAPSDPRGFGNRAAAYLKVMAPAECIRDCNKAIELDPNFAKAYVRKAQALFMLKDYNKCIDACNEASEVDRREPNTGKNLREIESQLSKCMSAMASQRQNETEEETMARIQKDPEVLGILQDPAMQAILGQARENPAALMEHMKNPTVKSKIEKLIASGVIRLG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0031072 (heat shock protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0009408 (response to heat), GO:0009266 (response to temperature stimulus), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0035966 (response to topologically incorrect protein), GO:0035967 (cellular response to topologically incorrect protein), GO:0006986 (response to unfolded protein), GO:0071310 (cellular response to organic substance), GO:0034605 (cellular response to heat), GO:0034620 (cellular response to unfolded protein)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Protein phosphatase methylesterase 1 (PME-1) (EC 3.1.1.-) (Q94F26)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
InterPro domains:
- IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [43-334]
- IPR000073: Alpha/beta hydrolase fold-1 (domain) [81-320]
- IPR016812: Protein phosphatase methylesterase, eukaryotic (family) [1-349]
Sequence:
MDSSSNLNPLREDTSEEHLEPIEAPASVFAARPLRPPSTNSSEKYSPVEWKSYFDKEDDISITGSDDVFHVYMAGNEGPVVFCLHGGGYSGLSFSIVASKIKEKARVVAMDLRGHGKSVSENELELSLETMSNDVLAVIKELYGDSPPAIVLVGHSMGGSVAVQVAANKTLPSLAGLVVVDVVEGTAISSLIHMQKILSNRMQHFPSIEKAIEYSVRGGSLRNIDSARVSIPTTLKYDDSKHCYVYRTRLEETEQYWKGWYDGLSEKFLSSPVPKLLLLAGTDRLDRTLTIGQMQGKFQMIVVKHTGHAIQEDVPEEFANLVLNFISRNRIGPHGVEIPGMWKPSQQTKT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0016298 (lipase activity), GO:0052689 (carboxylic ester hydrolase activity), GO:0047372 (acylglycerol lipase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:0044237 (cellular metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0019637 (organophosphate metabolic process), GO:0006793 (phosphorus metabolic process), GO:0006629 (lipid metabolic process), GO:0006644 (phospholipid metabolic process), GO:0006796 (phosphate-containing compound metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Fast skeletal muscle troponin T (Fast troponin T isoform a) (Troponin T type 3A (skeletal, fast)) (Troponin T3a, skeletal, fast) (Q9I8U9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
InterPro domains:
- IPR027707: Troponin T (family) [7-223]
- IPR001978: Troponin (family) [39-175]
- IPR038077: Troponin domain superfamily (homologous_superfamily) [109-230]
Sequence:
MSDTEDIEQHFEEEKPKFKPTAPKIPDGEKVDFDDIQKKRHNKDTLELQCLIDAHFEHRQKEEEELIALRERIEKRRSERAEQQRIRTEQEKERHARREEERLRKEEADAKKKAEEDAKKKSALSSMGSNYSSYLQKADSKKGGKKQTEREKKKKILAERRKQLNIDHLNEDKLRDKAQELYEWIKTLESEKFEHMERLKRQKYEVTTLRRRVEELSKFSKKGAAARRRK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0003779 (actin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0009653 (anatomical structure morphogenesis), GO:0071840 (cellular component organization or biogenesis), GO:0030029 (actin filament-based process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0032989 (cellular component morphogenesis), GO:0061061 (muscle structure development), GO:0044085 (cellular component biogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0016043 (cellular component organization), GO:0030036 (actin cytoskeleton organization), GO:0010927 (cellular component assembly involved in morphogenesis), GO:0042692 (muscle cell differentiation), GO:0055001 (muscle cell development), GO:0006996 (organelle organization), GO:0030239 (myofibril assembly), GO:0031032 (actomyosin structure organization), GO:0097435 (supramolecular fiber organization), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0007010 (cytoskeleton organization), GO:0051146 (striated muscle cell differentiation), GO:0055002 (striated muscle cell development), GO:0045214 (sarcomere organization), GO:0140694 (non-membrane-bounded organelle assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0099080 (supramolecular complex), GO:0030017 (sarcomere), GO:0005737 (cytoplasm), GO:0036379 (myofilament), GO:0043292 (contractile fiber), GO:0043229 (intracellular organelle), GO:0005865 (striated muscle thin filament), GO:0043228 (non-membrane-bounded organelle), GO:0099081 (supramolecular polymer), GO:0099512 (supramolecular fiber), GO:0030016 (myofibril), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015629 (actin cytoskeleton)
Protein: AFG2 interacting ribosome maturation factor (V9GYQ8)
Organism: Homo sapiens (Human)
Function: Not known
InterPro domains:
- IPR029159: Ribosome biogenesis protein C1orf109-like (family) [1-191]
Sequence:
MTQDRPLLAVQEALKKCFPVVEEQQGLWQSALRDCQPLLSSLSNLAEQLQAAQNLRFEDVPALRAFPDLKERLRRKQLVAGDIVLDKLGERLAILLKVRDMVSSHVERVFQIYEQHADTVGIDAVLQPSAVSPSVADMLEWLQDIERHYRKSYLKRKYLLSSIQWGDLANIQALPKAWDRISKDEHQDLVQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044085 (cellular component biogenesis), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0042273 (ribosomal large subunit biogenesis), GO:0042254 (ribosome biogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005634 (nucleus)
Protein: Probable glutathione peroxidase 8 (GPx-8) (GSHPx-8) (EC 1.11.1.9) (Q8TED1)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
InterPro domains:
- IPR036249: Thioredoxin-like superfamily (homologous_superfamily) [46-198]
- IPR013376: Glutathione peroxidase Gpx7, putative (family) [46-198]
- IPR029760: Glutathione peroxidase conserved site (conserved_site) [104-111]
- IPR000889: Glutathione peroxidase (family) [20-204]
Sequence:
MEPLAAYPLKCSGPRAKVFAVLLSIVLCTVTLFLLQLKFLKPKINSFYAFEVKDAKGRTVSLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLAFPCNQFGESEPRPSKEVESFARKNYGVTFPIFHKIKILGSEGEPAFRFLVDSSKKEPRWNFWKYLVNPEGQVVKFWKPEEPIEVIRPDIAALVRQVIIKKKEDL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016209 (antioxidant activity), GO:0004601 (peroxidase activity), GO:0005515 (protein binding), GO:0016491 (oxidoreductase activity), GO:0016684 (oxidoreductase activity, acting on peroxide as acceptor), GO:0042802 (identical protein binding), GO:0004602 (glutathione peroxidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0048523 (negative regulation of cellular process), GO:0008219 (cell death), GO:0050794 (regulation of cellular process), GO:0012501 (programmed cell death), GO:0060548 (negative regulation of cell death), GO:0010941 (regulation of cell death), GO:0033554 (cellular response to stress), GO:0097190 (apoptotic signaling pathway), GO:0097193 (intrinsic apoptotic signaling pathway), GO:0006974 (cellular response to DNA damage stimulus), GO:0043069 (negative regulation of programmed cell death), GO:0043067 (regulation of programmed cell death), GO:0006915 (apoptotic process), GO:0043066 (negative regulation of apoptotic process), GO:0042981 (regulation of apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0031090 (organelle membrane), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098827 (endoplasmic reticulum subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0005789 (endoplasmic reticulum membrane)