Protein: Protein LIKE EARLY STARVATION, chloroplastic (Q5EAH9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Binds preferentially to highly ordered alpha-glucans, such as starch and crystalline maltodextrins. Involved in the organization of the starch granule matrix, thus influencing starch turnover by modulating the accessibility of starch polymers to modifying and degrading enzymes involved in phosphorylation, hydrolyzes and synthesis, including starch synthases (SSI and SSIII), starch phosphorylases (PHS1), isoamylase, beta-amylase, glucan water dikinase (GWD) and phosphoglucan water dikinase (PWD).
Subcellular location: Plastid, chloroplast stroma {ECO:0000269|PubMed:17631522, ECO:0000269|PubMed:27207856}. Note=Binds to starch granules in chloroplasts. {ECO:0000269|PubMed:17631522, ECO:0000269|PubMed:27207856}.
InterPro domains:
- IPR052495: Alpha-glucan-binding chloroplastic protein (family) [61-576]
Sequence:
MALRLGVSIGAALGSSHWDDGQRVRQRDFSASVNFTAPVTSRRSLRGSRTGVRILRVSNEGRESYLDMWKNAVDREKKEKAFEKIAENVVAVDGEKEKGGDLEKKSDEFQKILEVSVEERDRIQRMQVVDRAAAAISAARAILASNNSGDGKEGFPNEDNTVTSEVTETPKNAKLGMWSRTVYVPRSETSGTETPGPDFWSWTPPQGSEISSVDLQAVEKPAEFPTLPNPVLEKDKSADSLSIPYESMLSSERHSFTIPPFESLIEVRKEAETKPSSETLSTEHDLDLISSANAEEVARVLDSLDESSTHGVSEDGLKWWKQTGVEKRPDGVVCRWTMIRGVTADGVVEWQDKYWEASDDFGFKELGSEKSGRDATGNVWREFWRESMSQENGVVHMEKTADKWGKSGQGDEWQEKWWEHYDATGKSEKWAHKWCSIDRNTPLDAGHAHVWHERWGEKYDGQGGSTKYTDKWAERWVGDGWDKWGDKWDENFNPSAQGVKQGETWWEGKHGDRWNRSWGEGHNGSGWVHKYGKSSSGEHWDTHVPQETWYEKFPHFGFFHCFDNSVQLRAVKKPSDMS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0030246 (carbohydrate binding), GO:0030247 (polysaccharide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0009629 (response to gravity), GO:0060255 (regulation of macromolecule metabolic process), GO:0044249 (cellular biosynthetic process), GO:0031323 (regulation of cellular metabolic process), GO:0005975 (carbohydrate metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0009606 (tropism), GO:0044262 (cellular carbohydrate metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:0009630 (gravitropism), GO:0044264 (cellular polysaccharide metabolic process), GO:0010675 (regulation of cellular carbohydrate metabolic process), GO:0016051 (carbohydrate biosynthetic process), GO:0005976 (polysaccharide metabolic process), GO:0032881 (regulation of polysaccharide metabolic process), GO:0034637 (cellular carbohydrate biosynthetic process), GO:0006109 (regulation of carbohydrate metabolic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:2000904 (regulation of starch metabolic process), GO:0009958 (positive gravitropism), GO:0033692 (cellular polysaccharide biosynthetic process), GO:0044042 (glucan metabolic process), GO:0000271 (polysaccharide biosynthetic process), GO:0006073 (cellular glucan metabolic process), GO:0009250 (glucan biosynthetic process), GO:0005982 (starch metabolic process), GO:0019252 (starch biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009532 (plastid stroma), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009570 (chloroplast stroma), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle)