lokahq/bioreason-rl huggingface dataset:
Protein: Heterogeneous nuclear ribonucleoprotein D (A0A8M9QC46)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm. Nucleus
InterPro domains:
- IPR000504: RNA recognition motif domain (domain) [54-218]
- IPR035979: RNA-binding domain superfamily (homologous_superfamily) [51-243]
- IPR012956: CARG-binding factor, N-terminal (domain) [1-54]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [46-249]
Sequence:
MSEEQFLGEDPTMKMEENDDGEGFGEEQMSGDNGGQGEAEGSKIDASKNEEDEGKMFVGGLSWDTTKKDLKDYFTKFGEVVDCTLKLDPLTGRSRGFGFVLFKEAESVEKVITQKEHKLNGKVIDPKKAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFDAYGEVESIELPMENKTNKRRGFCFITFKEEEPVKKIMEKKYHNIGLSKCEVKVAMSKEQYQQQQQWGGRGGYTSRGRGRGGPNQNWNQGYGNYWNQGYGNYGNYGYNNQGYGGYGGYDYSGYNNYYGYDQQSGYGKSQRRGGHQNSYKPY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0035295 (tube development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0055123 (digestive system development), GO:0048565 (digestive tract development), GO:0061008 (hepaticobiliary system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Calcium homeostasis modulator 1 (E7F2J4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
- IPR029569: Calcium homeostasis modulator family (family) [1-310]
Sequence:
MDKFRIMVQFLQANQESFMNGICGIMALASAQMYSSFEFTCPCLPDYNYAYGIGILIVPPIWFFLLGYVMNNNISVLTEEWKRPVGKRSKDPAVLRYMFSSMTQRALIAPAVWIAVTLMDGKSFLCAFSPTADLSEFVNESYQSLSQKELLKIQAKIPCKDIFEEHEIISREAATRYIRCLSQACGWTFLMVITLVAFLVRAIRPCFTQAAFLKTKYWSHYIDTERKLFDETCKEHAKSFAKVCIQQYFESISGEIVSQLPQSPAKKGKGNKDEDGEKQKSDEERLLGIRKEGDMNKVLWNWHTCKPPLLLSKRTEEMNGHAHLDTHSLTDERHTKKKAVVYYSKV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0015267 (channel activity), GO:0022839 (monoatomic ion gated channel activity), GO:0022836 (gated channel activity), GO:0005244 (voltage-gated monoatomic ion channel activity), GO:0022832 (voltage-gated channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0032501 (multicellular organismal process), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0003008 (system process), GO:0016043 (cellular component organization), GO:0050877 (nervous system process), GO:0044085 (cellular component biogenesis), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0043933 (protein-containing complex organization), GO:0071705 (nitrogen compound transport), GO:0007600 (sensory perception), GO:0022607 (cellular component assembly), GO:0015931 (nucleobase-containing compound transport), GO:0065003 (protein-containing complex assembly), GO:0007606 (sensory perception of chemical stimulus), GO:0015748 (organophosphate ester transport), GO:1901264 (carbohydrate derivative transport), GO:0015711 (organic anion transport), GO:0015867 (ATP transport), GO:0006862 (nucleotide transport), GO:0050909 (sensory perception of taste), GO:0051259 (protein complex oligomerization), GO:0015868 (purine ribonucleotide transport), GO:0015865 (purine nucleotide transport), GO:0051291 (protein heterooligomerization), GO:0051503 (adenine nucleotide transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Carbonic anhydrase Xb (A0A8M2BBM0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Does not have a catalytic activity
InterPro domains:
- IPR023561: Carbonic anhydrase, alpha-class (family) [30-294]
- IPR036398: Alpha carbonic anhydrase domain superfamily (homologous_superfamily) [26-309]
- IPR001148: Alpha carbonic anhydrase domain (domain) [30-300]
- IPR041878: Carbonic anhydrase-related protein X/XI (family) [45-301]
Sequence:
MPHVWEFVLILNINVIFVEAQPVSSKLHDGWWAYKDVVQGSFIPVPSFWGLVNTAWNLCAIGKRQSPVNIETSRMIFDPFLNPLRLNAGQRKVSGTMYNTGRHVSLRPDKSHLVNISGGPLSYSYRLEEIRLHFGSEDNRGSEHLLNGQAFPGEVQLIHYNQDLYLNYSDAVRSPNGIAVVSIFMKISEPTNVFLNRMLNRETVTRITYKHDAYLLMGLNIEELYPETSRFITYEGSITIPPCLETATWILMNKPIYISQIEMQSLRLLSQNQPSQIFLSMGDNMRPTQTLHQRCIRTNINFSQRRDCPNNRMLRPQYRVNEWLLK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016835 (carbon-oxygen lyase activity), GO:0016836 (hydro-lyase activity), GO:0004089 (carbonate dehydratase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0007610 (behavior), GO:0007626 (locomotory behavior), GO:0036269 (swimming behavior)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Double-stranded RNA-binding protein Staufen homolog 1 (A0A8M1PJS2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site
Subcellular location: Cytoplasm. Rough endoplasmic reticulum
InterPro domains:
- IPR014720: Double-stranded RNA-binding domain (domain) [74-455]
- IPR032478: Staufen, C-terminal (domain) [550-660]
- IPR044475: Staufen 1, third double-stranded RNA binding domain (domain) [284-350]
- IPR051740: Double-stranded RNA-binding domain-containing protein (family) [21-699]
Sequence:
MSQLQFQAPGNPAPSSAPLQLAPPQPGFSIPCGTAPLPSESASHPLRNSALPSASATPFCNPTVSNMANPKEKTPMCLVNELARYNKIQPEYKLLSEEGPAHSKIFSVRLTLGDQHWDAEGTSIKKAQHSAASSALAQTTLPKPSHRSPRHPGKSPGGIYKGSEYNVTHTVELNALCMKLGKKPIYKPIDAYQGMRPAFNYNIRAPSPYARSMQHYYYPFPPVGPVLYHMELSIGGQQFHGKGRTRQAAKHDAAAKAIKYLQKEPILQQITEMTDEPAQENLNKSEISQVFEIALKRNMPVDFEVLKEAGAPHMKSFVVRVVVGEFAGEGEGKSKKIAKKQAAIAVLEELRRLPQLPATDKIPLRIKKKSKSIIKLQTSPEYGQGMNPISRLAQIQQAKKEKEPEYTLVTERGLPRRREFVMQVSVAGQNAEGMGPSKKVAKRNAAEKMLELLGFKVPQPQPPKPALKTDEKPPAKKLGDGRKVTFFEPGSMEKAGLVVSKEEDFRLPFLSHQQLPAGILPMVPEVAQAVGANQGPHAKDYGRTAAPNPANATVTAMIANELLYAGTSPTAEGILKTNNSLAHRPQGPLTRPSEQLSYLANVQGLQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQSNERTANGPMSGCTKQDLEGDALLKPANSSTMGKTLDGTA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0007276 (gamete generation), GO:0007281 (germ cell development), GO:0048468 (cell development), GO:0030154 (cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Large ribosomal subunit protein eL22 (Q0VFW0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR038526: Large ribosomal subunit protein eL22 superfamily (homologous_superfamily) [7-126]
- IPR002671: Large ribosomal subunit protein eL22 (family) [6-122]
Sequence:
MAPKRQTVVRKNKKGACWKFTLDCTHPVEDGILDSANFETFLKEKVKVNGKTGNLGNVVQIVRQKNKINVTSEKQFSKRYLKYLTKKYLKKNNLRDWLRVVASDKESYELRYFQISQDDEESDADE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0030097 (hemopoiesis), GO:0060216 (definitive hemopoiesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Agouti-related protein (A0A8M1P467)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R. Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner
Subcellular location: Golgi apparatus lumen. Secreted
InterPro domains:
- IPR007733: Agouti (family) [2-125]
- IPR036836: Agouti domain superfamily (homologous_superfamily) [70-125]
- IPR027300: Agouti domain (domain) [83-122]
Sequence:
MMLNTVIFGWFLVNVVVMASHPHLRRRENSFILTSDTDSLPEMEHLEINSAEEKILEDLEAYDEDLGKAVHLQRRGTRSPSRCIPHQQSCLGHHLPCCNPCDTCYCRFFKAFCYCRSMDNTCKNEYA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (signaling receptor activator activity), GO:0048018 (receptor ligand activity), GO:0005179 (hormone activity), GO:0005184 (neuropeptide hormone activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0043473 (pigmentation), GO:0032501 (multicellular organismal process), GO:0048066 (developmental pigmentation), GO:0007154 (cell communication), GO:0007610 (behavior), GO:0007631 (feeding behavior), GO:0050795 (regulation of behavior), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0007632 (visual behavior)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0036477 (somatodendritic compartment), GO:0005615 (extracellular space), GO:0005576 (extracellular region), GO:0044297 (cell body), GO:0043025 (neuronal cell body)
Protein: Family with sequence similarity 49 member A (A0A8M2B7R9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Lipid- anchor
InterPro domains:
- IPR039789: CYFIP-related Rac1 interactor (family) [1-324]
- IPR009828: CYRIA/CYRIB, Rac1 binding domain (domain) [18-320]
Sequence:
MGNLLKVLTCTDFDQGPNFFLDFENAQPTDCEREVWNQVNAVLQESESILSGLQAYKGAGQEIRDAIQNPNDMLLQERAWNSVCPLVIRLKKFYAFSLKLEQALQSLLESLTCPPYTPTQHLEREQALAKQFAEILHFTLRFDELKMRIPAIQNDFSYYRRTISRNRLNNMNLDIENEVNNEMANRMSLFYAEATPMLKTLSTATTNFVTENKTLPLENTTDCLSTMASVCKVMLETPEYTSRFNSEDTLLFCMRVMVGVIILYDHVHPNGAFNKSSKIDMKGCIKVLKDQPADNVEGLLNALKFTTKHLNDESTPKNIRTMLQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0002682 (regulation of immune system process), GO:0050793 (regulation of developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0051239 (regulation of multicellular organismal process), GO:0002520 (immune system development), GO:0050794 (regulation of cellular process), GO:0045595 (regulation of cell differentiation), GO:0002694 (regulation of leukocyte activation), GO:1903706 (regulation of hemopoiesis), GO:2000026 (regulation of multicellular organismal development), GO:0048534 (hematopoietic or lymphoid organ development), GO:0050865 (regulation of cell activation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048732 (gland development), GO:1902105 (regulation of leukocyte differentiation), GO:0051249 (regulation of lymphocyte activation), GO:0048538 (thymus development), GO:0060284 (regulation of cell development), GO:0045619 (regulation of lymphocyte differentiation), GO:0050863 (regulation of T cell activation), GO:0045580 (regulation of T cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0042995 (cell projection), GO:0043226 (organelle), GO:0120025 (plasma membrane bounded cell projection), GO:0043227 (membrane-bounded organelle), GO:0005929 (cilium)
Protein: Opioid receptor, delta 1a (A3QJX7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane; Multi-pass membrane protein
InterPro domains:
- IPR017452: GPCR, rhodopsin-like, 7TM (domain) [70-323]
- IPR001418: Opioid receptor (family) [80-334]
- IPR000276: G protein-coupled receptor, rhodopsin-like (family) [55-331]
Sequence:
MEPSVIPGADIPDLYSINPFNVTFPDDVLSFVPDGRNYTEPNPVKSPAGIIIAISITALYSVICVVGLLGNILVMYGVVRYTKLKTATNIYIFNLALADALATSTLPFQSTKYLMNTWPFGELLCKVVIAIDYYNMFTSIFTLTMMSVDRYIAVCHPVRALEFRTPIKAKIINVCIWILSSAVGVPIMIMAVTRVTNQNTTVCMLKFPDPDWYWDTVTKICVFIFAFVVPVLVITICYGLMILRLKSVRLLSGSKEKDRNMRRITRMVLVVVAAFIICWTPIHIFIIVKTLVDINQKNPFVIASWHLCIALGYTNSSLNPVLYAFLDENFKRCFRDFCLPFRTRADQSNLNRARNATREPVSVCAPSDTGKKPV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0001653 (peptide receptor activity), GO:0008528 (G protein-coupled peptide receptor activity), GO:0004930 (G protein-coupled receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007186 (G protein-coupled receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Leucine-rich glioma-inactivated protein 1 (F6NUE1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm. Secreted. Synapse
InterPro domains:
- IPR011041: Soluble quinoprotein glucose/sorbosone dehydrogenase, beta-propeller domain superfamily (homologous_superfamily) [292-527]
- IPR000483: Cysteine-rich flanking region, C-terminal (domain) [158-207]
- IPR009039: EAR (repeat) [210-531]
- IPR051295: Leucine-rich glioma-inactivated/LGI-related (family) [6-535]
- IPR005492: Leucine-rich glioma-inactivated , EPTP repeat (repeat) [211-529]
- IPR001611: Leucine-rich repeat (repeat) [101-159]
- IPR003591: Leucine-rich repeat, typical subtype (repeat) [99-146]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [24-212]
Sequence:
MCLRRAAVLCVLLAALVLGGRRRSSRCPAPCTCSKDNALCANTGAIPRSFPQDVISLSFVKSGFTEIPKESFIHTPALHLLLFTANSFDSINEDAFLGLPHLEYLFIENNQIKSISPFAFRGLKSLIHLSLAYNNLETLPKDLFKGMEALTKVDLRGNLFSCDCKLKWLVDWMFHTNATVDQIFCNGPEGYQGKKINDLEAQTFDCITTDFTLLKSLEFQSISVEAFSFAGDQFVVFAQPFSGRCSFMEWDHVQMEFRNFDNITSTSTVICKPLVIDSQLFIIVAQLFGGSHIFKRDVSANKFIRIQDIDILKIRKPNDVEIFEVDGESFFIIADSSKAGSTTIYKWNGNGFYSYQSLHPWHRDTDVEYLDISGKPHLILSSSSQRPVVYQWSRGSAQFERRTDIPEMEDVFAVKHFTVKNELYICLTRFIGDSKVMRWDGSMFTEIQTVASRGSMVFQPFSVASWQYAILGSDYAFTRVYRWDAKKRQFVPFQELNIQAPRAFSLVFIDNREFLLGSSFKGQTRIYEHLVLDLSS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0007272 (ensheathment of neurons), GO:0007610 (behavior), GO:0008366 (axon ensheathment), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007626 (locomotory behavior), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development), GO:0042552 (myelination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: protein-serine/threonine phosphatase (A0A8M1P874)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Mitochondrion matrix
InterPro domains:
- IPR036457: PPM-type phosphatase-like domain superfamily (homologous_superfamily) [83-358]
- IPR000222: PPM-type phosphatase, divalent cation binding (binding_site) [122-130]
- IPR015655: Protein phosphatase 2C (family) [56-345]
- IPR001932: PPM-type phosphatase-like domain (domain) [84-346]
Sequence:
MSVALLVRYATLSGSRVCSRAAFNLTNAHQEDPRRALHTPSSPRFSNSRFDPDSSGRPTTWDSFGIWDNRIDEPILLPSSIRYGKLIPKVNLSRVGSASQIGQRKENEDRYQMSQMTDNIMYFAVFDGHGGAEAADFCHKNMEKHIKDIAAEETNLEFVLTKAFLEVDKALARHLHFSADASVLSAGTTATVALLRDGIELVVGSVGDSRAMMCRKGKAVKLTVDHTPERKDEKERIRRSGGFITWNSLGQPHVNGRLAMTRSIGDFDLKATGVIAEPETKRISLHHVHDSFLALTTDGINFIMNSQEICDVINQCHDPKEAAQRISEQALQYGSEDNSTIIVVPFGAWGKHKSSEVSFSFSRSFVSSGRFA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0004721 (phosphoprotein phosphatase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0016791 (phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0048519 (negative regulation of biological process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0050794 (regulation of cellular process), GO:0048523 (negative regulation of cellular process), GO:0035295 (tube development), GO:0060548 (negative regulation of cell death), GO:0010941 (regulation of cell death), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0007399 (nervous system development), GO:0055123 (digestive system development), GO:0043069 (negative regulation of programmed cell death), GO:0043067 (regulation of programmed cell death), GO:0072359 (circulatory system development), GO:0048732 (gland development), GO:0007417 (central nervous system development), GO:0048565 (digestive tract development), GO:0061008 (hepaticobiliary system development), GO:0031016 (pancreas development), GO:0007507 (heart development), GO:0042981 (regulation of apoptotic process), GO:0001889 (liver development), GO:0043066 (negative regulation of apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: MAC-inhibitory protein (A0A8M1Q769)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Lipid- anchor, GPI-anchor
InterPro domains:
- IPR045860: Snake toxin-like superfamily (homologous_superfamily) [19-98]
- IPR056949: CD59 glycoprotein (family) [24-93]
- IPR016054: Ly-6 antigen/uPA receptor-like (domain) [22-101]
Sequence:
MKLSLGLFLLVCCMTLSLGSSLRCYKCEDYAGGRCSVQQPCSYEDACLHLHEKGGKTIRRCIRYTDCDNSRLSQQFPSISEYTYRCCNTDLCNGGPLTTAGSLFLSLLAVFTGLFHCMIC
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0015267 (channel activity), GO:0015079 (potassium ion transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0005261 (monoatomic cation channel activity), GO:0005267 (potassium channel activity), GO:0046873 (metal ion transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0006950 (response to stress), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006952 (defense response), GO:0043207 (response to external biotic stimulus), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0042742 (defense response to bacterium), GO:0050829 (defense response to Gram-negative bacterium), GO:0050830 (defense response to Gram-positive bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)