lokahq/bioreason-rl huggingface dataset:
Protein: ubiquitinyl hydrolase 1 (A0A8M9NZE1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm. Nucleus
InterPro domains:
- IPR002653: Zinc finger, A20-type (domain) [876-911]
- IPR051346: OTU Domain-Containing Deubiquitinase (family) [83-683]
- IPR003323: OTU domain (domain) [177-357]
Sequence:
MTLDMDAVLSDFVRSTGAEPGLARDLLEGKNWDLSAALSDFEQLRQVHAGSLSCSFVEESEYPSIEKEMARTGRPLLHRQDEAVQAATEKRLSRGISHASSTIVSLARSHVSSTGGTNEQLLDTPLCTFQLPDLTVYRDDFRGFIERDLIEQSMMVALEQAGRLNWWTRLGTGCQSLLPLATSGDGNCLLHAASLGMWGFHDRDLMLRKSLYALMDHGQEREALKRRWRWQQTMQNKESGLVYTEEEWQKEWNELLKLASSEPRIHYSTNGSSGAESQEEPVYESLEEFHVFVLAHVLRRPIVVVADTMLRDSGGEAFAPIPFGGIYLPLEVPANKCHRSPLVLAYDQAHFSALVSMEQKDSSKEQVVIPLTDSDHKMLPLHFAVDPGADWEWGKDDNDNVMLASVTLSLEAKLHLLHCYMTVTWLPLPCEVQAPLAQPESPTASAGEDARTPPDSGESDKESVSSSSNGNGDSSTTGTSGTTGKTSGGSSSSSSSSSNSSGGTTGTIGKEKGKKDKEKDKDKDKKRADSVANKLGSFGKSLGSKLKKNVGGLMPGKNASGTGGKQEGQEKKKGSLRGRKGSKDSSPSIQTGSEDSGKGSPSSTSERQNGGYSSESDPFKYSSDVKVSLSILRSAMQGERKYIFSALLTTSNRQPFQEEMIQRYLVDAEERFHAEQEQRREAERKAAGGLASTTGPQMKKDGPELSYRGFESKEEVTDSSPPNFNALKSSSFSPVMYSGVVPIPRHTFIDHSPSPMTQHLHMHHGYMDTRRQLAGGSPSSYPGLPSYATLPRHCPLAQGPPHAQYHPPSASLGSPSRIITPCLTSFPQEHDPTDYPSEPSGAYTNGLRDLRSTLDSRNGPMPVRHYSLGSAGGLANLQSSKCRTPTCNYYGHPETGNYCSYCYREELKRRETEPAIHRF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008234 (cysteine-type peptidase activity), GO:0019783 (ubiquitin-like protein peptidase activity), GO:0101005 (deubiquitinase activity), GO:0004843 (cysteine-type deubiquitinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007166 (cell surface receptor signaling pathway), GO:0007219 (Notch signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform X1 (A0A8M3ANW4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR001806: Small GTPase (family) [350-642]
- IPR001849: Pleckstrin homology domain (domain) [616-859]
- IPR002110: Ankyrin repeat (repeat) [1027-1106]
- IPR036770: Ankyrin repeat-containing domain superfamily (homologous_superfamily) [996-1111]
- IPR001164: Arf GTPase activating protein (domain) [877-1000]
- IPR037278: ARFGAP/RecO-like zinc finger (homologous_superfamily) [880-992]
- IPR038508: ArfGAP domain superfamily (homologous_superfamily) [860-995]
- IPR051282: Arf-GAP with GTPase, ANK repeat and PH domain-containing protein (family) [237-1126]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [348-523]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [614-859]
Sequence:
MNRTGTSQSKTTYLISLTLVKVETAEENELEKSRPAVEGAVYSTDGAKHVMHPGSNNEGEERQKMGEAEAGESIKFSVEQEILQSPREEKALFTDGVQCGDRQKSMISPTTENGRARESSGIPQTSYPRDVARHLGDIPVRATQRPVSLLKTHGGGRELKESRESIHASSKSLDRKDSRTRIQSPTSPTPGSFRASWAVSEVKPCDDDLKVVGVGMKRPTEGDLIAMRTQSPRAERLKAGSTSLPTPVALITKPQRKGKSRTLDNSDLNCLSEDLLKCKGGQMVPDYRTAQSQGASARDRKMLRFISGIFTKSTPVAVSTTIVTPVYSLQRESSEEEASCANSQEWTLTRTIPELRLGVLGSIRSGKSALVNRFITGSYLPLESHEGGRYKKEVLVEGQSQLLLIREESGPPSAQLCNWLDGLILVFSLENEASFQEVYKNYSELSAHRNIAEIPIIAVGTQDKISSTNARVIEDKRVQQLCIDVRRCTYYETCATYGLNVDRVFNEMTQKIVAAKKQAALLASCKSLPNSPSHSGASTPVSGPGQASNGAQSSDYPSSLPSTPVISHKDIRGGASGDGVTQRNPPRRRTSLFANRRGSDSEKRSSDSRSDTSRSVPIKQGTLWKRSERSLNKEWKKKYVTLSNSGMLTYHSNINEFLQNAQGKEMDLLRVTVKVPGKRLHRAAAPGAPSPGPALVPVPGVNGLSKDKQTPEGGAASNLLTVEEASRAGLSYPNDQKVKRCPSSVSNKGFSVDSSIEGATSPPLGKEHMPSSPMTDRKKKKRNRSINLKGDAAAGQAEAKRKMWKLKSFGSLRNINKTEEESVDFIIISSTGQSWHFEAQSQEDRDAWVQAIESQILASLQSCESRNKARRNSQSEAVALQAIRNAKGNDLCVDCAAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDVWPSELTKVLSAIGNHMANHIWETCTQGCQKLTPEATREQRESWIRAKYEQRAFVSPLPAQCSEDTMSTWLLKAVINRDLPNLLLLLAHSTKELINIPPEGAGQQHHSALHAACQLGDVVMTQLLVWYGSDVKSKDPQGRTALTLARQAGSKECAEILVQHGCPSETSPTSPTPVLSRKSSITSVGRVNSRRRVS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0001944 (vasculature development), GO:0072359 (circulatory system development), GO:0007507 (heart development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: dynamin GTPase (A0A8M9PZL4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR022812: Dynamin (family) [7-750]
- IPR000375: Dynamin stalk domain (domain) [215-498]
- IPR001849: Pleckstrin homology domain (domain) [532-639]
- IPR030381: Dynamin-type guanine nucleotide-binding (G) domain (domain) [28-294]
- IPR001401: Dynamin, GTPase domain (domain) [6-294]
- IPR045063: Dynamin, N-terminal (domain) [34-207]
- IPR003130: Dynamin GTPase effector (domain) [660-751]
- IPR019762: Dynamin, GTPase region, conserved site (conserved_site) [57-66]
- IPR020850: GTPase effector domain (domain) [665-756]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [3-304]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [534-659]
Sequence:
MGNRGMEELIPLINKLQDAFSSIGQSCNLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLVNNKAEYAEFLHCKGRKFVDFDEVRQEIEAETDRITGSNKGISPIPINLRVYSPNVLNLTLIDLPGMTKVAVGDQPPDIEHQIRDMIMQFITRESCLILAVTPANMDLANSDALKVAKEVDPQGLRTIGVITKLDLMDEGTDARDILENKLLPLRRGYIGVVNRSQKDIDGRKDIRAALAAERKFFLSHPSYRHMAERMGTPHLQKALNQQLTNHIRDTLPGLRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKCIEGSGDQVDTAELSGGARINRIFHERFPFELVKIVFDEKELRREISHAIKNVHGVRTGLFTPDLAFEAIVKKQIIKLKEPCLKCIDLVIQELINTFRQCTNKLSSYPRLREETERIVTTYVREREGKTKDQVLLLIDTELSYINTNHEDFIGFANLDLRRLDDGTIPGYSNNSAQQRNIVNKKRAIPNQVIRKGWLTLNISIMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKLRDVEKGFMSTKHIFAIFNTEQRNVYKDLRQIELACDSQEDMDSWKASFLRAGVYPEKDQVESEEAAPADSFSMDPQLERQVETIRNLVDSYIGIVNKTIRDLMPKTIMHLMINSAKDFIHSELLAYLYSSGDQNSLMEESADQAQRRDEMLRMYHAIKEALSIIGDISTSTISTPVPPPVNDSWIPETSPTPQRRPPTSAPPPNRPPAVRGPTPGPPPLNPTPSFAAPPIPSRPGQPMNAFGNSSQDPFSAPPQIPSRPARIPPGVPSRRPPGAPNRPTIIRPAEPSLLD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009790 (embryo development), GO:0061061 (muscle structure development), GO:0048729 (tissue morphogenesis), GO:0009888 (tissue development), GO:0002009 (morphogenesis of an epithelium), GO:0061053 (somite development), GO:0060429 (epithelium development), GO:0009792 (embryo development ending in birth or egg hatching), GO:0060026 (convergent extension), GO:0043009 (chordate embryonic development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0012505 (endomembrane system), GO:0005905 (clathrin-coated pit), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane)
Protein: Carboxypeptidase A6 isoform X3 (A0A8M9PUE3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
Sequence:
MALRSTDVSSNVKSAVLLGCVLILCTAPNNVDSYLYNNRYVGDQVFRIIPSSKPEVQAVKQLFQNLTVDLWQPNSASLIRENSSIDVHVRRDKTHWLRNHLHQEHIYYEVLISNLQTEIEKQTGYRSSRKRRSELQYDYEVYHPLEEIQSWMFEMNRTHSHLVDLFSIGQSYEGRPLYVLQVKAKGQDG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008238 (exopeptidase activity), GO:0004177 (aminopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0006508 (proteolysis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Protocadherin 18b isoform X1 (A0A8M2B3F9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR050174: Protocadherin/Cadherin-related Cell Adhesion (family) [26-872]
- IPR013164: Cadherin, N-terminal (domain) [36-117]
- IPR020894: Cadherin conserved site (conserved_site) [240-580]
- IPR015919: Cadherin-like superfamily (homologous_superfamily) [137-685]
- IPR002126: Cadherin-like (domain) [32-696]
Sequence:
MGTTKHSSDWNVLFCKTLLKLMLLAAVAHNVSGKTLKYKVLEEQRVGTVIARLKEDVAGLLAKLPSSVSPRFRAMQRGSTPLLSVREEDGEISIATKIDREKLCEKNLNCTIEFDVITIPTEYLQLFHIQVEVLDINDNSPQFSRAIIPIEISESASVGTRFPLDSAVDPDVGENALHTYSLTRNNFFKIDIRTRTDGAKYADLVVMRELDRETQSSYQLQLTASDSGVPPKSGSTLLKISISDSNDNSPAFDEQAYVVNLLENSSLGTLLVDLNATDPDEGNNGKIVYSFSSHVPPKILETFKINPDNGHITLIKKVDYETTSSYEIDVQAQDMGPNSIPGHCKIIIKVVDVNDNKPKININLMTQGKEEVAYISEASPVDTFIALVRVDDSDSGINGEVVCRLHGHGHFRLQKTYENNYMILTNVSLDREKRSEYSLTVIAEDRGTPSLSTIKHFTVQVQDENDNPPRFEKSRYEIFKSENNSPGAYLTSVVATDPDLGPNGQVTYSIVESQVQGSSISTYVTIDPSNGAVYALRSFDREEVGRLSFTVQARDGGSPAFLSSNTTVLLTILDENDNPPIIVAPLLSNHTAEVPLWRHAESGHLVTIIKATDRDAGANSELTCSIVGGNDEGLFVIDPRRCELRTNGSVEASGREGFDLAILVQDRGASIRLSARAVLHISLRDYPESYSLNPSDINNQSPLDVSMIIIISLGAICGVLLIVMVMFATRCSREQKDPRHSYNCRVAESTYQNHPKKPARQIHKGDITLVPTINGTLPVRAHPRSPSASPAPESRQSHHSRQSLNSLVTISSNHVPENFALELAHATPPVEQVSQLLSILHQGQYQPRPSFRGNKYTRSYRYALNEMDKFSLKDSGRGDSEAGDSDCEMGRESPLLGEGFSELFTPDGHHRLHPTMKLCTEECRVLGHSDQCWMPPLPSPASSDYRSNLYIPGEDPQQKATPEVPQSGESTLRKKSFSTFGKESEEGEGEADDGEDLCGTTSLLSEMNSVFQRLLPSSLDNYSETNETEKATACAAGVGSLERRKGHLPGKPSPATYQQNVAVWAANTHFQNPGHGHAPASHMTALVAPLPAPLPAPMPASASCSKWLPAMEEIPENHEEDELESVLGHLHGKRCDSRSEIMDASELVAEINKLLQDVRQS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0032989 (cellular component morphogenesis), GO:0000902 (cell morphogenesis), GO:0016043 (cellular component organization), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0022008 (neurogenesis), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0048858 (cell projection morphogenesis), GO:0030182 (neuron differentiation), GO:0032990 (cell part morphogenesis), GO:0048666 (neuron development), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0048699 (generation of neurons), GO:0031175 (neuron projection development), GO:0048812 (neuron projection morphogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Protocadherin-18 isoform X2 (A0A8M2B6N3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR050174: Protocadherin/Cadherin-related Cell Adhesion (family) [25-873]
- IPR013164: Cadherin, N-terminal (domain) [31-112]
- IPR020894: Cadherin conserved site (conserved_site) [126-574]
- IPR015919: Cadherin-like superfamily (homologous_superfamily) [132-674]
- IPR002126: Cadherin-like (domain) [27-688]
Sequence:
METSKGTVLCATLLKLALLVTLAGYTTAATLKYQVYEEQKVGTVIARLREDVADVLSKLPSSIPLRFRAMQRGSASLLSVRDQDGEISIRTKIDREKLCEKNLNCTIEFDVLTLPTEHLQLFHIEVEILDINDNAPQFARPVIPIEISETAAVGTRIPLDSATDPDVGENSLNTYSLTPSDFFKIDILTRTDGAKYAELVVLKELDREVRASYELQLTASDRGVPPKFGTTLLKISIADSNDNNPVFEKPSYVINLLENSPLGSLLIDLNATDPDEGANGKIIYSFSSHVSPKILETFKINSDNGHLTLMRKVDFESTNSYDIDVQAQDMGPNSMPAHCKVIIKVVDVNDNKPDISVNLMSTGNEEIAYISETAPVDTFVALVSVNDLDSGLNGEVECRLYGQGHFRLQKSYEKNYMILTNVTLDREKRSEFSLTVIAEDKGSPSLSTIKNFIVEVQDENDNAPSFAKSRYEISKAENNSPGAYLSSVKASDPDLGPNGQVSYSILESMVHGSSISTYVTIDPSNGDIYALRTFDREDVSQISFLVQARDSGNPPLRSNVTVVLTVLDENDNRPVIMMPQLWNHTADVPVSKYAEIGDVVTVVRAMDHDAGANGDLSCSVVGGNEAGYFNMDPKTCEIRTNVSIQEVPRDHVELTILVQDHGTPTLSARALLRLSLYENIENLMNPHLTGGRNGDGPLDVSMIIIISLGAICAVLLLIMVAFALRCSREKKDTRSYNCRVAESTYQQHPKKPSRQIHKGDITLMPTVNGTLPIRAHHRSPTSSPGPERAHMGSRQSQHSRQSLNSLVTISSNHIPENFALELTHATPPVEQVSQLLSILHQGQYQPRPSFRGNKYSRSYRYALQDMDKFSLKDSGRGDSDAGDSDCEMGRDSPIDRLLGDGFGDLFHSDGHHRLHPVMRLCTEECRVLGHSDQCWMPSQASSDYRANMFIPGEESRPQVLEEDQQSVDSAKKSFSTFGKDNEEECGGSLLSEMNNVFQRLLPTSYADVRELDESTSQPASSIGMEIRKGFLPGKASSTGSAYPQGVAVWAANTHFQNPGGAVTSGHATTNHAASQAHLKWLPAMEEIPENYEEDDLESVLSQRQGKRNDTRHEVVDASELVAEINKLLQDVRQS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0007155 (cell adhesion), GO:0009790 (embryo development), GO:0048598 (embryonic morphogenesis), GO:0048729 (tissue morphogenesis), GO:0009888 (tissue development), GO:0098609 (cell-cell adhesion), GO:0016477 (cell migration), GO:0007369 (gastrulation), GO:0002009 (morphogenesis of an epithelium), GO:0055113 (epiboly involved in gastrulation with mouth forming second), GO:0098742 (cell-cell adhesion via plasma-membrane adhesion molecules), GO:0060429 (epithelium development), GO:0001667 (ameboidal-type cell migration), GO:0016339 (calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules), GO:0002011 (morphogenesis of an epithelial sheet), GO:0042074 (cell migration involved in gastrulation), GO:0001702 (gastrulation with mouth forming second), GO:0090504 (epiboly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Histone deacetylase complex subunit SAP130 isoform X3 (A0A8M6YZH6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
- IPR024137: Histone deacetylase complex subunit SAP130 (family) [18-1038]
- IPR031963: Histone deacetylase complex subunit SAP130, C-terminal domain (domain) [669-1022]
Sequence:
MQYSHYVVGIASDIRQKMSSQQFPRAALPPSAAAAAPGQASADSSGAGTHSVGSEDSSREVDHPQDPSLGSSSGSIGGLASFRDDKQETVVVRPYPQVQAPGQSPALPQHVPIQPSPPVTLAAPSVHLLQGQQPSLTEGSVKATLKPPMPSRLIAPAPALSQGHIPVPAKVSGHITVPLESSIAPASIPVATISGQQGQSNLHQLMATNVQIFRGSAPLQIGSPATPHTFTSHLPRGAAAAAVMSSTKGPNVLRPAGGGSAGPSQPAAVQHIIHQPIQSRSLVTTSTAVLPTMVAPIPAARTQSPVINTTVTHATEMVHGRPVAIHPPPATINIQRPPTPRDTATRITLPSHPAIGGQKAQPPHTVTQKPIFNTVTPVAAATVAPILATNTVPSATTTGSAAHTQMTSSTIVTMTMASHSSHATAVTTSAIPVAKVVPQPIAHTSHSPRIQQEYSGERPNLIPISGHRSSPNPVTMEARSDNRPSVPVQFQYFLPTYPSPSYPLSHTYTPITSSVSTIRPYPVTAPAQSSALPAQTGVGVATTMHLNQMQLMALPSAQISTQNIQPASMTAQGIQPAPIGVQGLHAAAPISTQTVQQAPVTTQQPQSEAKPAGVVLAESPAFVTNPIGSTFSGTQPVTTIVQTHTGAGAPTLVSSPRPSILRKKPVTEGVKPKPDIHVAMAPPVMAAVEALVGHVGEQQTLSTPVQHHSQAIPTLLAPPAPAPPSQPTAVLSALPATMAVTPPVPASMANAVASPTQPAASSTAALSSTLPEVKIKQEAEPMDTSQAVPLAPSLTGPAPSLSSQSSTLTVSSQPGELLPGASPRKKPRKQQHVISTEETEMVETNSTDEERASSRAPGNRMERHESPPREYVDEDGVRYVPVRPRPPHTHLRQYRNPWKAAYHHFQRYSDIRVKEEKKGSLQDMANQRGVACRAQGWKVHLCAAQLLQLSNLEHDVYSRLTTLQEGLIPKKRAGADDDLHRINELIQGNMQRCKLVMDQVTEARDTMMKVLDHKDRVLKLLNKNGTPKKSSKLKRKERA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0007610 (behavior), GO:0035295 (tube development), GO:0009790 (embryo development), GO:0001966 (thigmotaxis), GO:0021508 (floor plate formation), GO:0048729 (tissue morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0030537 (larval behavior), GO:0007418 (ventral midline development), GO:0033504 (floor plate development), GO:0009888 (tissue development), GO:0048731 (system development), GO:0007626 (locomotory behavior), GO:0033505 (floor plate morphogenesis), GO:0007417 (central nervous system development), GO:0007399 (nervous system development), GO:0060429 (epithelium development), GO:0021915 (neural tube development), GO:0009792 (embryo development ending in birth or egg hatching), GO:0008345 (larval locomotory behavior), GO:0043009 (chordate embryonic development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0140513 (nuclear protein-containing complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031519 (PcG protein complex), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Troponin T, slow skeletal muscle isoform X2 (A0A8M9P738)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity
InterPro domains:
- IPR038077: Troponin domain superfamily (homologous_superfamily) [145-259]
- IPR001978: Troponin (family) [66-195]
- IPR027707: Troponin T (family) [5-259]
Sequence:
MSDVEEEYEEQAEAEEEEEETTEEAGTEEAQEEEEERPRPKPMVPQLAPPKIPEGERVDFDDIHRKRMEKDLLELQTLIEAHFEQRKKEEEELIGLKDRIERRRFERAEQQRVRAEKERDRQTRIAEERQRKEDEEAKKRADDEAKKKKVLSNMGANFGGFLAKAEQKRGKRLTGREIKRKTLSERRAPLGIENMREDALRQRAQEMWNWIYELESEKFDLLDQMKKQKYEIVVLLNRISHAQKFKKGHGKGKVGGRWK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0009653 (anatomical structure morphogenesis), GO:0030029 (actin filament-based process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0032989 (cellular component morphogenesis), GO:0016043 (cellular component organization), GO:0061061 (muscle structure development), GO:0044085 (cellular component biogenesis), GO:0030036 (actin cytoskeleton organization), GO:0010927 (cellular component assembly involved in morphogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0022607 (cellular component assembly), GO:0042692 (muscle cell differentiation), GO:0006996 (organelle organization), GO:0031032 (actomyosin structure organization), GO:0030239 (myofibril assembly), GO:0055001 (muscle cell development), GO:0097435 (supramolecular fiber organization), GO:0070925 (organelle assembly), GO:0007010 (cytoskeleton organization), GO:0051146 (striated muscle cell differentiation), GO:0055002 (striated muscle cell development), GO:0045214 (sarcomere organization), GO:0140694 (non-membrane-bounded organelle assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0099080 (supramolecular complex), GO:0030017 (sarcomere), GO:0005737 (cytoplasm), GO:0036379 (myofilament), GO:0043292 (contractile fiber), GO:0043229 (intracellular organelle), GO:0005865 (striated muscle thin filament), GO:0043228 (non-membrane-bounded organelle), GO:0099081 (supramolecular polymer), GO:0099512 (supramolecular fiber), GO:0030016 (myofibril), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015629 (actin cytoskeleton)
Protein: YTH domain-containing family protein (A0A8M2BEG4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Specifically recognizes and binds N6-methyladenosine (m6A)- containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing
InterPro domains:
- IPR007275: YTH domain (domain) [429-563]
- IPR045168: YTH domain containing protein (family) [72-587]
Sequence:
MSTTSIDPQTSKGQDAKVQNGSLHQKETVHDNDFEPYLTGQSNPNNSYQSMTDPYLSSYYAPSIGFPYPLSEAPWSTGGDPPIPYLTPYAPLSNGDHHFMHDTVFGQPGGLGSSIYPHRFNFFPENPAFSAWGTSGSQGQQTQSSAYGGSYSYPPSSLGGTLVPDGQTGFPSDTLNKAPGMNSLEQGMVGLKIGGDVTGGGSGVKTVGSVIGGGPVAAAVATGNGGTPIGLPPPKPTSWAAIASKPAKPQQLKVKSKPGMPMAGGTLPPPPIKHNMDIGTWDNKGPVTKVASSLPPHHHHQQQPPLHSQGHLPPHPHGLPPPPQPPMPSAQSLAQQMAMQGPPPPQPYQNHAPAPPPQTRWVAPRNRNPGYGGGGSVDSSGSSSGGGVGNGGGGGPPGSGAIESHPVLEKLRAAHSYNPKEFDWNLKNGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDSAFRAINGKGPVYLLFSVNGSGHFCGVAEMRSPVDYGTSAGVWAQDKWKGKFDVDWLFVKDVPNSQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIIATYKHTTSIFDDFSHYEKRQEEEEVNLEPAPIQNRSRLDQERQNRNKQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0048856 (anatomical structure development), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007166 (cell surface receptor signaling pathway), GO:0048729 (tissue morphogenesis), GO:0009888 (tissue development), GO:0002009 (morphogenesis of an epithelium), GO:0060429 (epithelium development), GO:0007219 (Notch signaling pathway), GO:0002011 (morphogenesis of an epithelial sheet), GO:0090504 (epiboly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)