lokahq/bioreason-rl huggingface dataset:
Protein: Transforming growth factor beta receptor type 3-like isoform X1 (A0A8M3AXW9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR001507: Zona pellucida domain (domain) [382-734]
- IPR055355: ZP-C domain (domain) [534-607]
- IPR055356: ZP-N domain (domain) [383-483]
- IPR058899: TGFBR3/Endoglin-like, N-terminal domain (domain) [54-358]
- IPR042235: Zona pellucida, ZP-C domain (homologous_superfamily) [531-762]
Sequence:
MSDLEFVNVCVMKILAAVLCLPLTVLGIAVSSRELQCSVSPVAALHPVQAQLERFEAGTGCASREGGAKETHVISVGGASSRQVTVVLRPLNPSRPIKRPVILVLSSQQAVRWVLENEGLSSNINVLVQLSVNSTAESSSLSVRVTQVPSLPRRPRVLLRWVLQRHATVTSLTHTTHSNRIYLRLGEDPSMPSECRLRSLFVSQNYQASELQDQEVHGCTPTDEPTDSEVHIIRLWSSGSSLCGSLQVEVSVSLLPPVASSALHRVVLILSSATAVNWALVAPQVKGHVMVYSSHSVSLPYRSPASDLTMTSTVTSDLLNTPDLLEWANQNGFSKVTSYTEADLANRFVIKLGAGKDSDDASSVWHHHDDITIDSADALSYQCEGGALTVTVDMQMLKTQVWPVTAVTLQDPECKAEFNGSHFLLVSPIISCGTEGEMDEASGRVHYTNTVLLWKQKPSEGLTNQTSPELWDESNPLAVHLSCVWSLPAPLSPSVVSPSLGVAPALAPSTPPAPPHAPPLWGPGADTTAASPLLSMELFVSEAFQQRTVGPCVISAHERVYVQISVDSSSALEAVELQSCLVSPLSDPQAHSGWPVIKDSCPSDSSFSLSLRESTDDDGGADDEEQNRRKSHPFSRWRHTESRIADDTARGFKHNADDIARRFKHKRPRARKAERRRRNDDEDRSLNTLRFSFVLRPVFNNSIQFLHCRLRVCDADEGPSGAAKHTCADGHPIPALTHIRASQKCKDRNLSRPVLVTYPAGFLAPPAGKLAQTPAEMSGQAPSATGAVEGSVLLVVFAAFLMGLSLMGALWCIYTHTGRHDLTQRISVIETTVPNPGFINPPILMEETSSFHDVNDTHNNF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0009790 (embryo development), GO:0009888 (tissue development), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0035239 (tube morphogenesis), GO:0061053 (somite development), GO:0048514 (blood vessel morphogenesis), GO:0060429 (epithelium development), GO:0002040 (sprouting angiogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0030312 (external encapsulating structure), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0031012 (extracellular matrix), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0062023 (collagen-containing extracellular matrix), GO:0031982 (vesicle), GO:0005770 (late endosome), GO:0005771 (multivesicular body), GO:0097708 (intracellular vesicle)
Protein: ELAV-like protein (A0A8M6YXB4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR002343: Paraneoplastic encephalomyelitis antigen (family) [38-203]
- IPR006548: Splicing factor ELAV/Hu (family) [35-228]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [27-353]
- IPR034915: HuC, RNA recognition motif 3 (domain) [269-353]
- IPR003954: RNA recognition motif domain, eukaryotic-type (domain) [38-344]
- IPR000504: RNA recognition motif domain (domain) [38-348]
- IPR035979: RNA-binding domain superfamily (homologous_superfamily) [35-351]
Sequence:
MVTIISTMETQVSNGPSGTSLPNGPVISTNGATDDSKTNLIVNYLPQNMTQEEFKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYVDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKDMEQLFSQYGRIITSRILVDQVTAGISRGVGFIRFDKRNEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTQLYQTAARRYTGPLHHQTQRFSSLSVLPRFSPITIDSMTSLAGVNLTGPTGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTSKQHKA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050793 (regulation of developmental process), GO:0050794 (regulation of cellular process), GO:0051239 (regulation of multicellular organismal process), GO:0045595 (regulation of cell differentiation), GO:2000026 (regulation of multicellular organismal development), GO:0051960 (regulation of nervous system development), GO:0060284 (regulation of cell development), GO:0050767 (regulation of neurogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0042995 (cell projection), GO:0120025 (plasma membrane bounded cell projection), GO:0043005 (neuron projection), GO:0030424 (axon)
Protein: Cullin-1 isoform X1 (A0A8M9PTY1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR001373: Cullin, N-terminal (domain) [21-516]
- IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [685-749]
- IPR019559: Cullin, neddylation domain (domain) [701-750]
- IPR016159: Cullin repeat-like-containing domain superfamily (homologous_superfamily) [17-407]
- IPR016158: Cullin homology domain (domain) [415-642]
- IPR045093: Cullin (family) [14-748]
- IPR059120: Cullin-like, alpha+beta domain (domain) [537-658]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [602-750]
- IPR036317: Cullin homology domain superfamily (homologous_superfamily) [411-684]
Sequence:
MSSTRGQNTHGLKQIGLEQIWDDLRSGIQQVYTRQSMARSRYMELYTHVYNYCTSVHQARPTGIPSSKPSKKTPTPGGAQFVGLELYKRLKDFLRSYLTNLLKDGEDLMDESVLKFYTQQWEDYRFSSKVLDGICAYLNRHWVRRECDEGRKGIYEIYSLALVTWRECLFRPLNKQVTNAVLKLVEKERNGETINTRLVSGVVQSYVELGLNEDDAFVKGPTLSVYKEYFEAQFLADTERFYTRESTEFLQQNPVTEYMKKAEARLLEEQRRVQVYLHESTQDELARKCEQVLIEKHLEIFHTEFQNLLDADKNEDLGRMYNLVSRITDGLGELKKLLESHIHNQGLAAIEKCGDSALNDPKMYVQTTLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTRMAQSSSKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLSNSEPLDLDFSIQVLSSGSWPFQQSCTFALPSELERSYQRFTAFYGSRHSGRKLTWLYHLSKGELVTNCFKNRYTLQASTFQMAILLQFNTENCYSVQQLADSTQIKTDILVQVLQILLKSKLLVLEDENANIDEMDFKPDTLIKLFLGYKNKKLRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQQLLAEVLNQLSSRFKPRVPVIKVTP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0035556 (intracellular signal transduction), GO:0038061 (NIK/NF-kappaB signaling)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0140535 (intracellular protein-containing complex), GO:1990234 (transferase complex), GO:0000151 (ubiquitin ligase complex), GO:0031461 (cullin-RING ubiquitin ligase complex), GO:0019005 (SCF ubiquitin ligase complex)
Protein: Ectodysplasin-A isoform X2 (A0A8M9Q921)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted
InterPro domains:
Sequence:
MLIDLHAAMEPKREPAKLEERERTQAACECQSQCNNCKIFLSLFILSLSLHLVTLFCYLDLRSELKREISQKNKDEVSSTGPVPHYEATEPVLQSPDTDHPTIGDQSRWRDEHTRGLDRVIHRTKRSETNGKKKGERKKGKKGPPGAPGPPGPPGPQGPPGIPGIPGIPGSNAMGPSGPPGPPGPQGPPGPQGPPGPQGPSGGEKGKHREAQPAVVHLQGQETTIQVKEEGVLKNWRMISIHQRVFKMHSRSGELEVLLDGTYFIYSQVEVYYLNFTDIASYEVMVDKTPFLRCTRSIETGQRKFNTCYTAGVCLLRARQRISIRMVYEDTSISMSNHTTFLGSIRLGDAPSAGHT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048731 (system development), GO:0009887 (animal organ morphogenesis), GO:0048513 (animal organ development), GO:0001501 (skeletal system development), GO:0060348 (bone development), GO:0042476 (odontogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Parathyroid hormone 1 receptor b isoform X1 (A0A8M9QMD4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein
InterPro domains:
Sequence:
MVSVEVSVALVLCCVLMGARALIDSDDVITRDEQIFLLIGARSRCERTIRAQSDVVRENNCAPEWDGIICWPTGKPNQMVAVLCPEYIYDFNHRGYAYRHCDASGNWEQVSIINRTWANYTECTTYLHTNHSDQEEVFERLYLMYTIGYSISLAALLVAVSILCYFKRLHCTRNYIHIHLFTSFICRAISIFVKDAVLYAVTNDGELEDGAVEQRPMVGCKAAVTLFLYLLATNHYWILVEGLYLHSLIFMAFLSDKNCLWALTIIGWGIPAVFVSIWVSARVSLADTQCWDISAGNLKWIYQVPILAAIVGFGL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0033218 (amide binding), GO:0042562 (hormone binding), GO:0017046 (peptide hormone binding), GO:0042277 (peptide binding), GO:0004888 (transmembrane signaling receptor activity), GO:0004930 (G protein-coupled receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009893 (positive regulation of metabolic process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0062013 (positive regulation of small molecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0062012 (regulation of small molecule metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0045834 (positive regulation of lipid metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0009891 (positive regulation of biosynthetic process), GO:0010565 (regulation of cellular ketone metabolic process), GO:0045923 (positive regulation of fatty acid metabolic process), GO:0019216 (regulation of lipid metabolic process), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0045723 (positive regulation of fatty acid biosynthetic process), GO:0042304 (regulation of fatty acid biosynthetic process), GO:0019217 (regulation of fatty acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Cell division cycle-associated protein 7 isoform X1 (A0A8M2BET8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm. Nucleus
InterPro domains:
- IPR018866: Zinc-finger domain of monoamine-oxidase A repressor R1 (domain) [301-398]
- IPR040221: CDCA7/CDA7L (family) [118-403]
Sequence:
MRSKKQQASPPSTRMNLRSYRSSTVLPMETSSSSSDDSCDSFGSDGFGNSKRPQRQTRSSTQMEKVFNVLPVTEEEDACSGFESELNDELTEMKMDSDAEACSPPRKTRKSFTLRVAMKFPTKRSSPSKPVKPEPKPKAETKDPESDSEGENFMLKRALNIKENKAMLAKLMAELDKVPGLFPGRAALTPGNVVRRVPRRSLEPIAARRRNPERTSRPHTRSRSLVDGPPSPPPEDEEEDKYSLVRRSRGYEDDDEEEQKEPRRRSYNSSLTIPHVVRPVEDITEAELENICINVREKTYNRATGSTCHQCRQKTTDTKTNCRNSECVGVRGQFCGPCLRNRYGEEVRDALLNPEWLCPPCRGICNCSFCRAREGRCATGVLVYLAKYHGYDNVHSYLKSLKKELEESE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0050793 (regulation of developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0002520 (immune system development), GO:0050794 (regulation of cellular process), GO:0045595 (regulation of cell differentiation), GO:0048534 (hematopoietic or lymphoid organ development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048732 (gland development), GO:1901532 (regulation of hematopoietic progenitor cell differentiation), GO:2000736 (regulation of stem cell differentiation), GO:0048538 (thymus development), GO:1902036 (regulation of hematopoietic stem cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Nucleophosmin (A0A8M2BKD3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus, nucleolus. Nucleus, nucleoplasm
InterPro domains:
- IPR004301: Nucleoplasmin family (family) [9-294]
- IPR036824: Nucleoplasmin core domain superfamily (homologous_superfamily) [10-115]
- IPR032569: Nucleophosmin, C-terminal (domain) [249-296]
- IPR024057: Nucleoplasmin core domain (domain) [15-115]
Sequence:
MSINTPELRLTGPVRAKMEDNIKDLSRPQMYLFGCSLKADKKEHKVDLDDDEAEHQLSLKSVCLGAEAEDKFHTVEMEGLTYDGKTTKITLAVLKPSVLPSLSLGGFEVTPPVSFRLQSGGGPVYISGQHFVSVKESDDEDEEEEENNTSPVKRPSNMTLAKVPQKKLKMDSDEDEDSDDDDDDDDDDDDDEEEDDDKQEKPAVKSPVKSTQKTPEKKKSADKQNGSPDKKAGTSGKPQTQTPQKVKDKSAAGPSGKTPSIPSLSEVKSKLTSAAKEGKPFPKTEQKFENFARSSFKISDKQVIKDLWNFVQSLKK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0060090 (molecular adaptor activity), GO:0030674 (protein-macromolecule adaptor activity), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0042393 (histone binding), GO:0140463 (chromatin-protein adaptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0050794 (regulation of cellular process), GO:0010941 (regulation of cell death), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0030097 (hemopoiesis), GO:0043067 (regulation of programmed cell death), GO:0042981 (regulation of apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005634 (nucleus)
Protein: Nephronectin isoform X2 (A0A8M2B6Z0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR000152: EGF-type aspartate/asparagine hydroxylation site (ptm) [134-272]
- IPR000998: MAM domain (domain) [465-612]
- IPR000742: EGF-like domain (domain) [51-284]
- IPR009030: Growth factor receptor cysteine-rich domain superfamily (homologous_superfamily) [119-233]
- IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [468-610]
- IPR049883: NOTCH1 EGF-like calcium-binding domain (domain) [119-232]
- IPR052235: Nephronectin domain-containing protein (family) [20-610]
- IPR024731: NELL2-like, EGF domain (domain) [248-283]
- IPR018097: EGF-like calcium-binding, conserved site (conserved_site) [244-270]
- IPR001881: EGF-like calcium-binding domain (domain) [119-284]
Sequence:
MWIIKFMLMWTCWIAVDADFDGRWSRQMSSSNGLCRYGGRIDCCWGWTRVSWGQCQPLCQHGCKHGECVGPNKCKCHPGYTGKTCNQDERGFVSPPLWHSHAPVFVPMDHQPIAAPSEDLNECGLKPRPCKHRCMNTFGSFKCYCLNGFMLLPDGSCANARTCSMANCQYGCEVMKGEVRCQCPSPGLQLAPDGRTCVDVDECAAGLAVCPRFRKCINTFGSYICKCHDGFDLQYVNGKYQCTDVNECSLGQHQCGPYATCYNTPGSYKCKCKEDYRGVGYDCKPIPKVVIDPPRPGKTTPSSNNNKGGNKIPGSDQKRTTTTVRPPVTAKRISPTITTTTTTTKPPPTKKITPPARVPVTTTRKPFIPTRKPPVLVTTKPKVPTHQHTTTKVPVVTAVVPFIPTRRPFTIPFVTPIDNSIKDITQKQRGDVHIPRNHGKNNVLGIDLDIELGNTEEELKDDPESGYLSCSFDHGLCGWIQRREGDLHWETSEDPSGGRYLTISEGGEKRGGRGAQLILPLKTPWNEGNLCLAFRHNMAGHHVGMLQVFVQKGRQHSPAVWGRTGGNGWRSTQITLWGNGLESVIVKGERRRGRKGEIALDDMSLKRGSCQEEHNLRRL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0050839 (cell adhesion molecule binding), GO:0005178 (integrin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0003206 (cardiac chamber morphogenesis), GO:0003170 (heart valve development), GO:0009887 (animal organ morphogenesis), GO:0048513 (animal organ development), GO:0061383 (trabecula morphogenesis), GO:0003205 (cardiac chamber development), GO:0060343 (trabecula formation), GO:0048731 (system development), GO:0060347 (heart trabecula formation), GO:0003171 (atrioventricular valve development), GO:0003007 (heart morphogenesis), GO:0061384 (heart trabecula morphogenesis), GO:0072359 (circulatory system development), GO:0007507 (heart development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062023 (collagen-containing extracellular matrix), GO:0005604 (basement membrane)
Protein: Nephronectin isoform X1 (A0A8M3B3H9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR000152: EGF-type aspartate/asparagine hydroxylation site (ptm) [151-289]
- IPR000998: MAM domain (domain) [482-629]
- IPR000742: EGF-like domain (domain) [66-301]
- IPR009030: Growth factor receptor cysteine-rich domain superfamily (homologous_superfamily) [203-303]
- IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [485-627]
- IPR049883: NOTCH1 EGF-like calcium-binding domain (domain) [136-249]
- IPR052235: Nephronectin domain-containing protein (family) [20-627]
- IPR024731: NELL2-like, EGF domain (domain) [265-300]
- IPR018097: EGF-like calcium-binding, conserved site (conserved_site) [261-287]
- IPR001881: EGF-like calcium-binding domain (domain) [136-301]
Sequence:
MWIIKFMLMWTCWIAVDADFDGRWSRQMSSSNGLCRYGGRIDCCWGWTRVSWGQCQPLYVLTRRVIGIRCQPQALCQHGCKHGECVGPNKCKCHPGYTGKTCNQDERGFVSPPLWHSHAPVFVPMDHQPIAAPSEDLNECGLKPRPCKHRCMNTFGSFKCYCLNGFMLLPDGSCANARTCSMANCQYGCEVMKGEVRCQCPSPGLQLAPDGRTCVDVDECAAGLAVCPRFRKCINTFGSYICKCHDGFDLQYVNGKYQCTDVNECSLGQHQCGPYATCYNTPGSYKCKCKEDYRGVGYDCKPIPKVVIDPPRPGKTTPSSNNNKGGNKIPGSDQKRTTTTVRPPVTAKRISPTITTTTTTTKPPPTKKITPPARVPVTTTRKPFIPTRKPPVLVTTKPKVPTHQHTTTKVPVVTAVVPFIPTRRPFTIPFVTPIDNSIKDITQKQRGDVHIPRNHGKNNVLGIDLDIELGNTEEELKDDPESGYLSCSFDHGLCGWIQRREGDLHWETSEDPSGGRYLTISEGGEKRGGRGAQLILPLKTPWNEGNLCLAFRHNMAGHHVGMLQVFVQKGRQHSPAVWGRTGGNGWRSTQITLWGNGLESVIVKGERRRGRKGEIALDDMSLKRGSCQEEHNLRRL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0050839 (cell adhesion molecule binding), GO:0005178 (integrin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0003206 (cardiac chamber morphogenesis), GO:0003170 (heart valve development), GO:0009887 (animal organ morphogenesis), GO:0048513 (animal organ development), GO:0061383 (trabecula morphogenesis), GO:0003205 (cardiac chamber development), GO:0060343 (trabecula formation), GO:0048731 (system development), GO:0060347 (heart trabecula formation), GO:0003171 (atrioventricular valve development), GO:0003007 (heart morphogenesis), GO:0061384 (heart trabecula morphogenesis), GO:0072359 (circulatory system development), GO:0007507 (heart development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062023 (collagen-containing extracellular matrix)
Protein: Melanocyte protein Pmel 17 isoform X1 (A0A8M2B993)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR022409: PKD/Chitinase domain (domain) [220-399]
- IPR000601: PKD domain (domain) [225-288]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [218-293]
- IPR035986: PKD domain superfamily (homologous_superfamily) [232-286]
- IPR059017: PMEL/NMB, N-terminal domain (domain) [36-202]
- IPR046846: PKAT, KLD domain (domain) [467-517]
- IPR045219: PKD- and KLD-Associated Transmembrane (family) [6-604]
Sequence:
MKLFSTIFILSSLSGGLTRQADRSNSNSRFNQYQTLNTKRFPVWNDGDPRYKTSWMGGQLKFDVGNDAPTLTGAKISFTIDIVFPHNQKVLPDGQVVWAKNCTINGTQFHEGEPVYPEENSWNAVSPNAHLFSRQGDKPPPYVFVWKTWGKYWQVCDGPSSSLTIDTDDVPLGSYIMDVVIYHYRQKDRFIPIGFASTQFSIIDQIPFAVSLTQVNDKDQGDHKFVQNRAVAFSITLHDPSEYLSKSDVTFNWNFGDGSGTVISRESTVTHTYIASGVFKPQVVVQAAIPDPSCSGPPNPPVEGSTANTFTSESPKHPSEHLATDHPTRHFSAPFVKSTPVSAMKTVPPAPTNGDPSKSSLERQVVDLVPEFKMSETLNTVTNTPLKATATDMVMVEDESIENQAHVSIIKRQAPNINGCVIYRYGSFSTDIEIIEGIESVQIVQVAVADGFLLTEMEQNAVDFTVSCQGSIPTEVCTIVSDADCHAPVMTICNAVSPSSDCQLILRHFFNDSGTFCINVSMANDVSMAVTNARVNINIGSRLTSAGAAALLLGILTVVSAMAAVAFAYKRLKGYQRLTEDPVACQSNDSGVCSMPALFWSLMNHQTVDQKKGVV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0043473 (pigmentation), GO:0071840 (cellular component organization or biogenesis), GO:0033059 (cellular pigmentation), GO:0016043 (cellular component organization), GO:0048753 (pigment granule organization), GO:0006996 (organelle organization), GO:0032438 (melanosome organization), GO:0016050 (vesicle organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0043227 (membrane-bounded organelle), GO:0120025 (plasma membrane bounded cell projection), GO:0005929 (cilium), GO:0097730 (non-motile cilium)