Protein: Laminin, alpha 5, isoform CRA_a (A6KMB1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane. Secreted, extracellular space, extracellular matrix, basement membrane
InterPro domains:
- IPR056863: Laminin/attractin/netrin-like, EGF domain (domain) [1864-1901]
- IPR002049: Laminin-type EGF domain (domain) [303-2165]
- IPR000742: EGF-like domain (domain) [359-2144]
- IPR010307: Laminin domain II (domain) [2630-2760]
- IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [2732-3686]
- IPR000034: Laminin IV (domain) [1652-1830]
- IPR009254: Laminin alpha, domain I (domain) [2193-2448]
- IPR050440: Laminin/Netrin Extracellular Matrix (family) [48-586]
- IPR001791: Laminin G domain (domain) [2734-3684]
- IPR008211: Laminin, N-terminal (domain) [43-303]
Sequence:
MAKRGGQLCVGCAPGARGPRSLAPLPLLLLAGLALVGEARIPGGDGFSLHPPYFNLAEGARITASATCGEEAPTRSASRPTEDLYCKLVGGPVAGGDPNQTIQGQYCDICIAANSNKAHPVSNAIDGTERWWQSPPLSRGPEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSTDFGHTYQPWQFFASSKRDCLERFGPRTLERITQDDDVICTTEYSRIVPLENGEIVVSLVNGRPGARNFSYSPVLRDFTKATNIRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHADVCDAKDPSDPFRLQCACQHNTCGGSCDRCCPGFNQQPWKPATTDSANECQSCNCHGHAYDCYYDPEVDRRNASQNLDNVYQGGGVCLDCQHHTTGINCERCVPGFYRAPDQPLDSPHVCQPCDCESDFTDGTCEDLTGRCYCRPNFTGERCSACAEGYVDFPHCYPLPSFPHNDTGEQVLPAGQIVNCDCNAAGTQGNACRKDPRLGRCVCKPNFQGNHCELCAPGFYGPSCHPCQCSSPGVANGLCDPESGQCTCRTGFEGDKCDHCALGYFHFPLCQLCGCSPAGTLPQGCDESGHCQCRPGFDGPHCDRCLPGYHGYPDCHACACDPRGSLDQQCGAGGLCHCRPGYTGATCQECSPGFYGFPSCIPCHCSADGSMHTTCDPTTGQCRCRPRVTGLRCDMCVPGAYNFPYCEAGSCHPAGLAPANPALPEAQAPCTCRAHVEGPSCDRCKPGYWGLSSSNPEGCTRCSCDPRGTLGGVTECQGNGQCFCKAHVCGKTCAACKDGFFGLDHADYYGCRSCRCDVGGALGQGCEPKTGACRCRPNTQGPSCSEPAKDHYLPDLHHIRLELEEAATPEGHAVRFGFNPLEFENFSWRGYAHMTAIQPRIVARLNVTSPDLFRLVFRYVNRGSTSVNGQVSVREEGKFSSCTNCTEQSQPVAFPPSTEPAFVTVPQRGFGEPFVLNPGTWALLVEAEGVLLDYVVLLPSTYYEAALLQHRVTEACTYHPSALHPTENCLLYAHLPLDGFPSAAGTEALCRHDNSLPRPCPTEQLSPLHPPLATCAGSDVDIQLEMAVPRPGRYALVVEYVSEYSHQEMGVAVHTPQRAPQQGMIDLHPCPYSSLCRGPARDTQHHLAVFHLDSEASIRLTAEQAHFFLHSVTLIPVEEFSAEFVEPRVFCVSSHGAFNPGSAACLASRFPKPPQPIVLKDCQVLPLPPDLPLTQSQELSPGASPVGPQPRPPTAVDPNAEPTLIRHPQGTVVFTTQVPTLGRYAFLLHSYQPVHPSFPVEVLIDGGRIWQGHANASFCPHGYGCRTLVSCEGQTMLDVTDNELAVTVRVPEGRWLWLDYILVVPEDAYSSSYLQEEPLDKSYDFISHCATQGYHISPSSSSLFCRNAATSLSLFYNNGALPCGCHEVGAVGPTCEPFGGQCPCRGHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQCICPPRTVPPDCLVCQPQSFGCHPLVGCEECNCSGPGVQELTDPTCDMDSGQCRCRPNVAGRRCDTCAPGFYSYPSCRPCDCHEAGTMASVCDPFTGQCHCKENVQGSRCDQCRVGTFSLDAANPKGCTRCFCFGATERCGNSNYARHEFMDMEGWVLLSSDRQVVPHEHRPEMELLHADLRLVADTFPELYWQAPPSYLGDRVSSYGGTLHYELHSETRRGDVFIPYESRPDVVLQGNQMSIAFLELAYPSPGQVHRGQLQLVEGNFRHLETHNPVSREELMMVLAGLEQLQIRALFSQTSSTVSLRRVVLEVASEAGGGPPASNVELCMCPANYRGDSCQECAPGYYRDTKGLFLGRCVPCQCHGHSDRCLPGSGTCVGCQHNTEGDQCERCRPGFVSSDPSDPASPCVSCPCPLAVPSNNFADGCILRNGRTQCLCRPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNMIFSDCDPLTGACRGCLRHTTGPRCESCAPGFYGNALLPGNCTRCDCSPCGTETCDPQTGRCLCKAGVTGQRCDHCLEGHFGFEQCQGCHPCACGPAAEGSECNPQTGQCHCRPGTTGPQCLECAPGYWGLPEKGCRRCQCPRGHCDPHTGRCTCPPGLSGERCDTCSQQHQVPVPGRPGSHGIHCEVCDHCVVLLLDDLERAGALLPSIREQLRGINASSTAWARLHRLNASIADLQSKLRSPLGPHNQTAEQLQTLEQQSISLQQDTERLGSQATGVQDQAGRLLDNTESTLVRAQKLLEIVQAVSRALNELASQGFPGNATTPSGEQLRWALAEVERLLWDMRTRDLGAPQAVAEAELAEAQRLMARVQEQLTSFWEENQALATHIRDQLAQYESGLMDLREALNHAVNTTREADELNSRNEERLREALQWKQELSQDNATLKATLQAASLTLAHVSELLQGIDKAKEDLEHLAASLDGAWTPLLKRMQAFSPASSKVDLVEAAEAHAQKLNQLAINLSGIIQGINQDRFIQRAVEASNAYSSILQAVQAAEDAAGHALRQASRTWEMVVQRGLAAGARQLLANSSALVETILGHQERLGLAHGRLQAAGTQLRDVRAKKNQLAAQIQEAQAMLAMDTSETSEKIAHAKAVAAEARDTAAHVQSQLQGMQKNVERWQSQLGGLRGQDLSQAERDASSSVSTLEKTLPQLLAKLSHLENRGVHNASLALSANIGRVRKLIAQARSAANKVKVSMKFNGRSGVRLRTPRDLADLAAYTALKFYIQSPVPAPEPGENTGDRFVLYMGSRQATGDYMGVSLRNQKVHWVYRLGEAGPTTLSIDENIGEQFAAVSIDRTLQFGHMSVTVEKHMVHEIKGDTVAPGREGLLNLNPDDFVFYVGGYPSNFTPPEPLRFPGYLGCIEMDTLNEEVVSLYNFEQAFKLTTAVDKPCARSKTTGDPWLTDGSYLDGSGFARITFEKQFSNTKRFEQELRLVSYNGIIFFLKQENQFLCLAVQDGTLVLLYDFGSGLKRADPLQPPQALTAASKAIQVFLLAGARKRVLVRVERATVFSVDQDNELEMADAYYLGGVPPEELPPSLRRLFPSGGSVRGCIKGIKALGKYVDLKRLNTTGISFSCTADLLMGRTMTFHGHGFLPLALPDVAPITGEVYSGFGFRGTQDDNLLYYRTSPDGPYQVSLRGGHVTLQFMNREVETQRVFADGAPHYVAFYSNVTRVWLYVDDQLQPVKSREGTTPMLQLQPEEPPRLLLGGLPMSGTFHNFSGCISNVFVQRLRGPQRVFDLHQNMGSVNVSVGCTPAQLQTSGATAQKVSRRSRQPSQDLTCMTPWLLGTIQDAYQFGGPGPSYLQFVGVSPSHRNRLHLSMLVRPHGASQGLLLYVAPLSSHSPSLVLFLNHGRFVAQTEGPGPQLQAQSRQHSRAGQWHRVSVRWGMQQVQLVVDGSQTWSQKAPHRRVHRAEGPQHYTLFVGGLPAGSYSSKLPVSVGFSGCMKKLQLDKRPLRAPTRMVGVTPCVSGPLEDGLFFPGSEGAVTLELPKAKMPHVSLELEVRPLAAAGLIFHLGQAHATPYVQLQLLTEQVLLRANDGAGEFSTWVTYPKLCDGQWHQVTVIKGRNTLRLEVDTHSNHTTGRLPETLADSPALLHLGSPPKSEAAWPEPPAYRGCLRKLLFNGAPVNMTASARIQGAVGMSGCPSGTLAISKQGKALTQRQANPSVFPLRWH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0050839 (cell adhesion molecule binding), GO:0005178 (integrin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0007155 (cell adhesion), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0098609 (cell-cell adhesion), GO:0034330 (cell junction organization), GO:0022607 (cellular component assembly), GO:0034329 (cell junction assembly), GO:0150115 (cell-substrate junction organization), GO:0007044 (cell-substrate junction assembly), GO:0031581 (hemidesmosome assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0043256 (laminin complex), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062023 (collagen-containing extracellular matrix), GO:0005604 (basement membrane)