Protein: Tyrosine-protein kinase (A0A8N7UW23)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR008266: Tyrosine-protein kinase, active site (active_site) [496-508]
- IPR001245: Serine-threonine/tyrosine-protein kinase, catalytic domain (domain) [381-629]
- IPR001849: Pleckstrin homology domain (domain) [4-114]
- IPR001452: SH3 domain (domain) [192-252]
- IPR050198: Non-receptor tyrosine kinases involved in cell signaling (family) [226-629]
- IPR000719: Protein kinase domain (domain) [381-635]
- IPR000980: SH2 domain (domain) [257-356]
- IPR001562: Zinc finger, Btk motif (conserved_site) [114-150]
- IPR020635: Tyrosine-protein kinase, catalytic domain (domain) [381-630]
- IPR017441: Protein kinase, ATP binding site (binding_site) [387-409]
- IPR036028: SH3-like domain superfamily (homologous_superfamily) [176-247]
- IPR036860: SH2 domain superfamily (homologous_superfamily) [249-400]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [366-628]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [1-154]
Sequence:
MADRVLEEVFIKRSQQKKKTSPLNFKERLFVLTHDKISYYDYDAEKAKRKSLKGYVDIEKIRCVEVVLPEDSAPPDRHYPFQIVYDEGPLYVFAKSDQIRKHWIHELKNVVRFNKDLMQKYHPCFWEDGVWKCCLQEVKQAMGCRVLETKNGGVFKRGSKNRDSRKPLPPTPEEEKPARPLPPEPPMPPAFSIGMTVIAEYEYAPMTTNDLELRKDEEYTLLEISDPNWFKAKDKYGKEGYIPSNYIVQALNGLEKYDWYCKNINRSQAENLLKTENKDGGFLVRDSGKFTGKYTVSVFTKAGGETSGSCRHYNILLTADGQFYLAEKHNFTNIPELINYHQHNAAGLVSRLKYIVSNRAQNAPCTAGLGYGSWEIDPRQLTFIRELGNGQFGVVKYGKWQGRHDVAIKMVKEGSMSEDDFIEEAKVMMKLCHGNLVQLYGVCTKQRPIYIVTEYLANGCLLNYLQERLSNPTSIVLLEMCKDVSEGMKYLEANQFIHRDLAARNCLVDSNGTIKVTDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLLYCKFSSKSDIWAFGVLMWEIYTQGRMPYDRWNNTEIVEKISAGHRLYRPQMANENVFAIMNSCWHERPDERPTFKELVEVIKDLLFSMQEI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0032501 (multicellular organismal process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0048856 (anatomical structure development), GO:0023057 (negative regulation of signaling), GO:0007275 (multicellular organism development), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0007389 (pattern specification process), GO:0050794 (regulation of cellular process), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0003002 (regionalization), GO:0010646 (regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0030111 (regulation of Wnt signaling pathway), GO:0030178 (negative regulation of Wnt signaling pathway), GO:0009952 (anterior/posterior pattern specification), GO:0060828 (regulation of canonical Wnt signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)