Protein: Microphthalmia-associated transcription factor isoform X1 (A0A8M9PEV1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
- IPR031867: MiT/TFE transcription factors, N-terminal (domain) [4-32]
- IPR021802: MiT/TFE transcription factors, C-terminal (domain) [227-342]
- IPR011598: Myc-type, basic helix-loop-helix (bHLH) domain (domain) [141-200]
- IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [138-233]
Sequence:
MPPGPGNSAPNSPMALLTLNPNCEKEMDDVIDDIIGLESSYSDDIMGLSLDPGLQMANTIPVSANLLDMYSNPGLPPPGISISNSCPANMTSVKREFSVTPSPALMHMMDKPSSCSKFESYQRPEGFPVEVEVRALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQREQHRTKELENRQKKLEHTNRNLLLRIQELEIQARAHGLAMASSALCASELAARAIKQEPLLGDCSQDMYTSTHAHPSCADMSRSSTLDLNNGTISFSDTHLSDTHAAKLDDILMDETLTSGATNESLISAASNESTHKDSMNMEENQHAC
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0048511 (rhythmic process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0043473 (pigmentation), GO:0048869 (cellular developmental process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0007623 (circadian rhythm), GO:0071704 (organic substance metabolic process), GO:0048066 (developmental pigmentation), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0030154 (cell differentiation), GO:0046483 (heterocycle metabolic process), GO:0044249 (cellular biosynthetic process), GO:0050931 (pigment cell differentiation), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0090304 (nucleic acid metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0018130 (heterocycle biosynthetic process), GO:0030318 (melanocyte differentiation), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0010467 (gene expression), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:0016070 (RNA metabolic process), GO:0032774 (RNA biosynthetic process), GO:0097659 (nucleic acid-templated transcription), GO:0006351 (DNA-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)