Protein: Centrosomal protein of 128 kDa (Q8BI22)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Note=Associates with the mother centriole
InterPro domains:
- IPR026652: Centrosomal protein of 128kDa (family) [1-1095]
Sequence:
MAESSSDSDHVRYRDGLSRWATRSFQRGVGSHSTVDVTAKVNTITNTLQDTTRNLRHVDQMLGRYREYSTGQAGAVGQLKEDLEQSINQLRSQRLRRSSGGRSVSVTSLSASDLDGGAVTENLRFAPTSPLKDYDLQGIKRNRFRTGVRFVSETDDMVQLHTFHQSLRDLSSEQVRLGDDLNRELFRRSRSDAETKRVLEELTGKLNEVQKPDVVSDRVERRLQEIEREMRLERELVERRHDQLGLVSLKLQEALKKQEAKADENEDVIKRKLRQSETEKSQLEQELEISRRLLSQSESNRETLLHQVEELRTQLIKAEGDQRGLQHQVPCISKQPLSHQDDQGDDRRFRRGVEREKLSLEKQMADLRVQLNFNSMASELEEVKRCMERKDQEKATLAAQIENLTRDLENREKQQLQMLDQLTEIQNHFETCEANRKRTDLQLSELSQHAEEATKQAEHYLSEFQRSETLREEAEKRREDLKAKAQESIRQWKLKHKKLERSMEKQAETLVQLTEKNNQFIKERDELKSQLCAALQQIENLRKELNDVLSKRALQEEELHCKEKKLNDIESHQAELELEVKNSLDTIHRLENELKRQSKSQSQIKAEKIHLEEEITELKKSQSQDKVKLLEMQESIKDLSAIRADLANKLAEEEKAKKAVFRDLSELTAQVKSKEEETATAITQLKLERDVHQRELEDLSSSLESVKLKHEQNIQELMKHFKKEKSEAESHIRMLKAESLEDKNMAKAHLGQLEKLKSQCEKLTEELTHTENENKKLKLKYQSLKEELDKKEKYISTEEEHLRRMEESRLHLKDQLLCLETEQESILGVIGKEIDEACKTFSRDSLEKLKVLTSGPQLHYDPHRWLAESKTKLQWLCEELKERESRERSMRQQLAACRQELRELTEHKESELLCLFEHIERQEQLLEEFHQEKRGLLEETQRKDEEVETLQDRVNALQMSTRVALDHLESVPEKLSLLEDFKDFRGASSLSEKTDGRYSKYSLHGDSVQQRRDDTKPRIKSFRDDRPLSAGSHAHGLDHSSSCQDHSRFLSSPQFSHSLPVFTKRTIATDPASIEGDTTSLPANGTSPQSKKEEHEIKKYKK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0015631 (tubulin binding), GO:0008017 (microtubule binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0051641 (cellular localization), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048870 (cell motility), GO:0008283 (cell population proliferation), GO:0022402 (cell cycle process), GO:0007049 (cell cycle), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0009566 (fertilization), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0033036 (macromolecule localization), GO:0050793 (regulation of developmental process), GO:0097722 (sperm motility), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0050794 (regulation of cellular process), GO:0007017 (microtubule-based process), GO:0048523 (negative regulation of cellular process), GO:0048609 (multicellular organismal reproductive process), GO:0051640 (organelle localization), GO:0007610 (behavior), GO:0007276 (gamete generation), GO:0007281 (germ cell development), GO:0061351 (neural precursor cell proliferation), GO:0044085 (cellular component biogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048515 (spermatid differentiation), GO:0120316 (sperm flagellum assembly), GO:0051649 (establishment of localization in cell), GO:0021695 (cerebellar cortex development), GO:0000226 (microtubule cytoskeleton organization), GO:0030534 (adult behavior), GO:0030317 (flagellated sperm motility), GO:0032886 (regulation of microtubule-based process), GO:0007283 (spermatogenesis), GO:0007626 (locomotory behavior), GO:0007018 (microtubule-based movement), GO:0007059 (chromosome segregation), GO:0060322 (head development), GO:0051656 (establishment of organelle localization), GO:0030900 (forebrain development), GO:0006810 (transport), GO:0001539 (cilium or flagellum-dependent cell motility), GO:0070727 (cellular macromolecule localization), GO:0045595 (regulation of cell differentiation), GO:0016043 (cellular component organization), GO:0031023 (microtubule organizing center organization), GO:0051128 (regulation of cellular component organization), GO:0007098 (centrosome cycle), GO:0007338 (single fertilization), GO:0030030 (cell projection organization), GO:0003341 (cilium movement), GO:0060284 (regulation of cell development), GO:0007286 (spermatid development), GO:1902115 (regulation of organelle assembly), GO:0001578 (microtubule bundle formation), GO:0022607 (cellular component assembly), GO:0007420 (brain development), GO:0022008 (neurogenesis), GO:0007399 (nervous system development), GO:0008344 (adult locomotory behavior), GO:0021591 (ventricular system development), GO:0007097 (nuclear migration), GO:0007417 (central nervous system development), GO:0008104 (protein localization), GO:0006996 (organelle organization), GO:0048232 (male gamete generation), GO:0060285 (cilium-dependent cell motility), GO:0070925 (organelle assembly), GO:0033365 (protein localization to organelle), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0035082 (axoneme assembly), GO:0060294 (cilium movement involved in cell motility), GO:0007010 (cytoskeleton organization), GO:0044380 (protein localization to cytoskeleton), GO:0060271 (cilium assembly), GO:0120031 (plasma membrane bounded cell projection assembly), GO:0044458 (motile cilium assembly), GO:0072698 (protein localization to microtubule cytoskeleton), GO:1905508 (protein localization to microtubule organizing center), GO:0071539 (protein localization to centrosome)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0140535 (intracellular protein-containing complex), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0097539 (ciliary transition fiber), GO:0005814 (centriole), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0005929 (cilium), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0031514 (motile cilium), GO:0097729 (9+2 motile cilium), GO:0015630 (microtubule cytoskeleton), GO:0036126 (sperm flagellum)