lokahq/bioreason-rl huggingface dataset:
Protein: Lipolysis-stimulated lipoprotein receptor isoform X2 (A0A8M2B4I8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell junction, tight junction. Membrane; Single-pass type I membrane protein
InterPro domains:
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [24-169]
- IPR008664: LISCH7 (domain) [182-229]
- IPR051874: Immunoglobulin-like domain-containing protein LISCH7 (family) [4-613]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [26-163]
- IPR007110: Immunoglobulin-like domain (domain) [34-157]
- IPR003599: Immunoglobulin domain subtype (domain) [25-162]
Sequence:
MSLGVIFTLLLFTGVTTGINVICTYPRYVVIMFQPVTLRCDFTTTSTTPPLITWKYKSYCRDPIQAALNPSSADNAIAQSNPNYNPNIECADSARTVRIVASKQTAVTLGKEYQGRQISITNNADLSIVQTAWGDSGVYVCSAASAQDLSGNGECYTELIVLERKSNTTDLLPGIDLLIMEDWLLVVLVVLGFLLLLLLIGICWCQCCPHTCCCYVRCPCCPERCCCPRALYEAGKMVKSGIPSQYAATAYAQSMYGQPAYGVGAAMPGIPMMPMQMGVGGPPSNGYGRDYDGASSIGQGSQVPLLQEHDAGGNRSGYRVQADQDGNPTRVLYYMEREVANLDPSRPGIAPVDGMSEVSSLHDGPDSRNRGRARPPQLTTVYDDVDENMSTISSVSQHMRRDEPRRGADSRGRARSMENLDDISRGYRDRDDYPPARRDGGPRGGRRGSDDEWSSSGRGYDPVDDRRRRDYSPDNRPRHGDSFRGAGFQGRRTRSRDDLMDLVRDPGRGGRDEYDDSFLREAMEKKKLGEQQRGRSRERLDSESDRSDRYRGHHSGPPPLPLVPASGNPDRRGNHSNFPPPPPPYTEDTDSLPSSKKSNLKKNGAVSRESLVV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0048856 (anatomical structure development), GO:0009888 (tissue development), GO:0048513 (animal organ development), GO:0007492 (endoderm development), GO:0031016 (pancreas development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction), GO:0070161 (anchoring junction), GO:0005911 (cell-cell junction), GO:0070160 (tight junction)
Protein: Regulator of G-protein signaling 3 isoform X4 (A0A8M3ASZ5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR034951: Regulator of G-protein signalling 3, RGS domain (domain) [351-464]
- IPR036305: RGS domain superfamily (homologous_superfamily) [339-469]
- IPR024066: RGS, subdomain 1/3 (homologous_superfamily) [345-465]
- IPR044926: RGS, subdomain 2 (homologous_superfamily) [372-451]
- IPR016137: RGS domain (domain) [347-466]
Sequence:
MLEPKQDEPCDLRGRRMTSEDDHSLGSLSDASATTASSPQSRSLTLLEELCTSLEETCHPVPPTPPPSTEGDDGRSTESSMNEIWREEECKEKETEESDFLHAQTKDCDDCDEKQVIIDEENASEVADTNAPSSSSSFIIPELRLDRSYSADALSTPGTDEEYDEDEDDEEEEEEEDSDDNYLERSDSKRRSMVEAGSCEKHPGGLSVQNSLRRRTHSEGSLLQDPRTTCFTSDNAINCMEVSGAHKGGWTLPSPKTLKKELTKNGGSMHQLCMLFSGRKLSASSECSCDVGPDGTKKKKSKNLAKDMKNRLAFLRRRNESPGSTPASKLDKTMKSVKPTPEEAMKWGESLDKLLVHKYGLAAFRAFLRTEFSEENLDFWLACEDYKKIKSQSKMTSKAKKIFAEFIAIQSCKEVNLDSYTREHTKENLQNINRSCFELAQRRIYGLMEKDSYPRFLRSELYMDLVNQKKPSTTSTSSSS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0008047 (enzyme activator activity), GO:0060589 (nucleoside-triphosphatase regulator activity), GO:0030695 (GTPase regulator activity), GO:0005096 (GTPase activator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0048519 (negative regulation of biological process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0023057 (negative regulation of signaling), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0009888 (tissue development), GO:0010646 (regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0009790 (embryo development), GO:0030111 (regulation of Wnt signaling pathway), GO:0030178 (negative regulation of Wnt signaling pathway), GO:0061053 (somite development), GO:0060429 (epithelium development), GO:2000050 (regulation of non-canonical Wnt signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Zinc finger protein 385C isoform X3 (A0A8M2BB30)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR013087: Zinc finger C2H2-type (domain) [224-314]
- IPR000690: Matrin/U1-C, C2H2-type zinc finger (domain) [290-320]
- IPR003604: Matrin/U1-C-like, C2H2-type zinc finger (domain) [66-321]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [199-327]
- IPR051845: Zinc finger protein 385 (family) [4-446]
Sequence:
MLIGTAAQGSPLLASLPMQGRPLQTPLDLKHFLPFRLSGSSPLSLFPNFNNMDPVQKAVINHTFGVPQSLKKKQNQAEAHYKGHKHARKLKALEAQKNKQQRRQQDNSHHNREREKDRERDKERERVKASAPDPPPALLDDTAIEGTAVSDPESALRVDDAHCSSVVLTPISEVSSADLCASSPHSQHPDALLEPSGDTSPPPQDSPAADTPAEKEPKKSKQHLHCPICKVTVNSSIQMEAHNSGTKHKLMMDGQSVLPRRRGKAMSSRPSCKSKRLASKGSLGVASKSFYCEVCEIHVNSETQLSQHMNSRRHKDRLAGKPPKPKFNPHAKSQPTSTVSQGVRWNGYAGGAVSAMKKVISQCNLSSLSSQTKLVLQKQLTKNLTASFLPTPLTPPTLCTVAANPLALRHPPGTTFIQTPILGPALFRPAPGPLRATHTPIIFSPY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0035295 (tube development), GO:0009790 (embryo development), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0048729 (tissue morphogenesis), GO:0035148 (tube formation), GO:0009888 (tissue development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0035239 (tube morphogenesis), GO:0007507 (heart development), GO:0060562 (epithelial tube morphogenesis), GO:0048568 (embryonic organ development), GO:0002009 (morphogenesis of an epithelium), GO:0007399 (nervous system development), GO:0060429 (epithelium development), GO:0048562 (embryonic organ morphogenesis), GO:0016331 (morphogenesis of embryonic epithelium), GO:0072359 (circulatory system development), GO:0072175 (epithelial tube formation), GO:0001838 (embryonic epithelial tube formation), GO:0001841 (neural tube formation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Steroid receptor RNA activator 1 isoform X1 (A0A8M2BL77)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR009917: SRA1/Sec31 (domain) [63-206]
- IPR040243: Steroid receptor RNA activator 1 (family) [1-206]
Sequence:
MSDRFVKPGNQEHGWNDPPQFSYGLQKDSGGQKRNILNKRVHAPQTTAGSGSEIQSTPLAGQTPPRGINPPPMDGVTPPPACPRVPSDGAVEAVQSETEPRFEDVQESLYWALNACRPNVKKQVCDDVERRLKVFEDMWKTGKLSLLVKRRMLGLSQELKRKNWDAADEIHRGLMVDHVSEVSQWMVGVKRLIAEARSLKPEQISSCTDAGS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0003008 (system process), GO:0003013 (circulatory system process), GO:0008015 (blood circulation), GO:0003015 (heart process), GO:0060047 (heart contraction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Myocyte-specific enhancer factor 2A isoform X6 (A0A8M9P9W4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
Sequence:
MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEKLRNKGHNDCPSPDPDDCFGHSPLMDDRFGKLNEESDLMYKRCGPTALPPQNFSMHVAVPVTNPNAMSYNPGASLSSQSLSAAASLSDGAMLSPPQGSMHRSVVPPQRPPSTGSTAGNGFVNPRGSPGLLGTPSGNGLGKVMPAKSPPPPGGNMGIGSRKPDLRVVIPPSSKGMMPPLSEEEEMELNTQRISSSQSTQPLATPVVSVTTPSLAPQGLVYSGMPTAYNSEYSLSSAELSSLQGFGSPGLSIGSVSAWQQHQLGQAALSSLVGGGHLPQGSNLSINTSQNVNIKSEPISPPRERVTPSGFPPQQQQPPSGRPDMGRSPVDSLSSSCSSYDGSDREDHRPDFHSPLGLGRPPAGGADERESPSVKRMRMDTWVT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048522 (positive regulation of cellular process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009891 (positive regulation of biosynthetic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0010468 (regulation of gene expression), GO:1902680 (positive regulation of RNA biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0045893 (positive regulation of DNA-templated transcription), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Trace amine-associated receptor 10b isoform X1 (A0A8M6Z3C0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein
InterPro domains:
Sequence:
MDIRINISHNGIWDKPFLCYEFSNRSCQKFVYPLETRIFLYILFSASSIITIIGNLLVIITVVHFRQLHTPTNYLILSLAVADLLVGGVVMPPSMLRSIETCWYLGDLFYRYYAICHPFQYHSKMTSLATLVMIIICWTVSAVLGFGMIFMELNILGVEDFYYENVDCNGRCLVFQSREVAVFMSLACFYIPAFVMLCVYLKILHEAQRQVQAIQSVNSELKKEGKATKTLAIIVGVFLTFWIPFFLCNLIDPFIGYSVPPLLFDLFLWVGYYNSTCNPIVYAFFYSWFRHAFRVILSGGIFQSNSSRTILL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0004930 (G protein-coupled receptor activity), GO:0008227 (G protein-coupled amine receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0009266 (response to temperature stimulus), GO:0009409 (response to cold), GO:0033554 (cellular response to stress), GO:0070417 (cellular response to cold)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Transcription factor SOX-5 isoform X1 (A0A8M9Q0N4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
- IPR051356: SOX/SOX-like transcription factors (family) [14-761]
- IPR009071: High mobility group box domain (domain) [561-631]
- IPR036910: High mobility group box domain superfamily (homologous_superfamily) [556-639]
Sequence:
MLTEPELPQEFNRMSSKRPASPYGGTDGEVVMATSRQRLEDEEVDGHAVIHLPLSSYCSKVSPRSPRLLDSPPTLHANMDQDGSKGLALSPYAQHNSSTSPSKQQQEDSSMRPGSEPGSASALGTPERRKGSLADVVDTLKQRKMEELIKNEPEEAPSIERLLSKDWKDKLLAMGSGNFGEIKGTPDSLAEKERQLMGMITQLSSLREQLLAAHEEQKKLAASQIEKQRQQMELAKQQQDQIARQQQQLLQQQHKINLLQQQIQQVQGQLPPLMIPVFPPDQRTLAAAAAQQGFLLPPGFNYKPGCSEPYPLQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGAKHSTVPQANLATGTLSPTSGQSEKNRSTPPPKPKDEGAQPLNLSSKPKASESKSPTSPASPQVPALKLGPGSLKHSAPSSIGGPPSRLSSIDLLSSITSAGYLNDHEAVTKAFQEARKMKEQLKREEQVLDAKVAAVNSLSLNNGRSEKVRFMEKAALESLSQQLKQSEESKFTHAMMDFGISGDSDGSPSVSDSRIFREARGRGSSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFTVGQQAQLPLSSAGVVYPGALSMAGMPSPQMPSEHSSMSSSPEPVPPTSQASYFKEVEPRVKEELRMDDGNGDAYDDFDYEDDDGDYGSDSENHITQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0043473 (pigmentation), GO:0048869 (cellular developmental process), GO:0048066 (developmental pigmentation), GO:0050931 (pigment cell differentiation), GO:0030154 (cell differentiation), GO:0030318 (melanocyte differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Vascular endothelial growth factor A isoform X1 (A0A8M2BBS4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR050507: Platelet-derived/Vascular endothelial growth factor (family) [24-250]
- IPR023581: Platelet-derived growth factor, conserved site (conserved_site) [106-118]
- IPR036841: Vascular endothelial growth factor, heparin-binding domain superfamily (homologous_superfamily) [196-250]
- IPR029034: Cystine-knot cytokine (homologous_superfamily) [67-178]
- IPR000072: PDGF/VEGF domain (domain) [70-166]
- IPR027928: Vascular endothelial growth factor, heparin-binding domain (domain) [196-250]
Sequence:
MSNLLSETFTNAFAKVRLSSDRVLKRFIRLLNSIMNFAVRVLQLFIVTLLYFSAVKSAYIPREGGRSTYDVVPFMEVYNKSLCRPREMLVEIQQEYPDDTEHIFIPSCVVLTRCAGCCNDEMMECTPTVTYNITLEIKRLKPLRHQGDIFMSFAEHSECQCRMKKDLPKEIEKKPRKGKGQKRKGKKNREKKRDFSQCEPCCSTCSERRRRLFVQDPETCQCSCKHSEADCRSRQLELNERTCRCDKPRR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (signaling receptor activator activity), GO:0048018 (receptor ligand activity), GO:0008083 (growth factor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0035239 (tube morphogenesis), GO:0048514 (blood vessel morphogenesis), GO:0002040 (sprouting angiogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005576 (extracellular region)
Protein: Nucleotide exchange factor SIL1 (A0A8M3AS71)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5
InterPro domains:
- IPR013918: Nucleotide exchange factor Fes1 (domain) [146-220]
- IPR011989: Armadillo-like helical (homologous_superfamily) [163-457]
- IPR016024: Armadillo-type fold (homologous_superfamily) [175-449]
- IPR050693: Hsp70 Nucleotide Exchange Factors and Inhibitors (family) [67-451]
Sequence:
MLTSRVMANKWRVRFGLTVTFWLLSLHLIFAHDVKSPTALLIKEDSDDLNNAEETHLEDEDPEDLEVFRPTDKWQTLRPGQAVPAGSHVRLNLQTGQREVKMGEEEGFKYWKDGNRQGMMNMDSHSFTAEELKKALKKFKKGADDPVDQQEEDAVRAKFWPMDELKKDMEALDMLVETDIQVMRRLLDQFNNTNSTTEEKVAALLDLEYLVHQVDNAQNLVSMGGMSLVIRSLNSTDVRLQECAAFVLGSAVSSNPSVQVEAVEGGALQKLLTLLATQRPMTVKKKVLFAVASLLRHFPFAQSHFLKLGGVQVLSELFQTPGAEAMRVRIITVLYDMIIEKELISQVGLDIIPDSSHQERLRQYAEVSLLPVLVEQGWCRLVPELLESPEHDWREKALRTLLAMMAQCQTQFKQNAGLTASLSELQKQYQELVLTEQDVGEEDGYFGEILTLVDSMVVKMRQV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0061061 (muscle structure development), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0060537 (muscle tissue development), GO:0007517 (muscle organ development), GO:0042692 (muscle cell differentiation), GO:0048880 (sensory system development), GO:0055001 (muscle cell development), GO:0007423 (sensory organ development), GO:0007519 (skeletal muscle tissue development), GO:0060538 (skeletal muscle organ development), GO:0001654 (eye development), GO:0014904 (myotube cell development), GO:0051146 (striated muscle cell differentiation), GO:0150063 (visual system development), GO:0014902 (myotube differentiation), GO:0048741 (skeletal muscle fiber development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Branchpoint-bridging protein (A0A8M3AU14)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns
Subcellular location: Nucleus
InterPro domains:
- IPR047086: Splicing factor 1, helix-hairpin domain superfamily (homologous_superfamily) [115-198]
- IPR045071: KH domain-containing BBP-like (family) [70-450]
- IPR004087: K Homology domain (domain) [206-299]
- IPR032570: Splicing factor 1, helix-hairpin domain (domain) [90-202]
- IPR001878: Zinc finger, CCHC-type (domain) [350-366]
- IPR055256: KHDC4/BBP-like, KH-domain type I (domain) [218-299]
- IPR036612: K Homology domain, type 1 superfamily (homologous_superfamily) [204-332]
Sequence:
MATGANATPLGKLHPSIGAKRGFDSGPGPGLMPPPGPSVPFPLQNFQPPQLSNPGFPQFPGAVSSALSNPIVVGQQSQAGGGDFGQKKRKRSRWSSETPDQKTVIPGMPTVIPPGLTRDQERAYIVQLQIEDLTRKLRTGDLGIPVNPEDRSPSPEPIYNSEGKRLNTREYRTRKKLEEERHSLITEMVGLNPEFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECCAKIMIRGKGSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSTEPRSITNTTLCTKCGGAGHISSDCKFTSSFAPRPGEPPQSAQDKARMDKEYLSLMAELGEAPVPSSGGGHNNAPPSGPRPSGPNNNQPPPNRPPWMNSGPTDNRNFHGMHQGPGGPHNFPPPMPNMGGPPMPPNPNGMPPPWMQPPPPPMGQGPAPPGHPMGPLPPWQQQAPPPPPTSSMATSAPMPWQQNTTTTSTPATGNLPPWQQPQQTAASASQPPPPMGNPSMVPPPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPMDPNFVTMMGIPGMPPYGMPPAPPPPPPQS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0060041 (retina development in camera-type eye), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0001654 (eye development), GO:0150063 (visual system development), GO:0043010 (camera-type eye development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)