Protein: Neurotrophic receptor tyrosine kinase 2 (A0A8I5KPC6)
Organism: Homo sapiens (Human)
InterPro domains:
- IPR000372: Leucine-rich repeat N-terminal domain (domain) [31-65]
- IPR013098: Immunoglobulin I-set (domain) [204-374]
- IPR020777: Growth factor receptor NTRK (family) [86-361]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [196-385]
- IPR003598: Immunoglobulin subtype 2 (domain) [209-273]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [32-185]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [203-383]
- IPR000483: Cysteine-rich flanking region, C-terminal (domain) [148-195]
- IPR050467: Leucine-rich repeat and fibronectin type-III domain-containing (family) [203-296]
- IPR031635: Growth factor receptor NTRK, leucine rich repeat C-terminal (domain) [151-195]
- IPR007110: Immunoglobulin-like domain (domain) [197-282]
- IPR001611: Leucine-rich repeat (repeat) [92-149]
- IPR020455: BDNF/NT-3 growth factors receptor NTRK2 (family) [16-343]
- IPR003599: Immunoglobulin domain subtype (domain) [203-284]
Sequence:
MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEPNSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHINFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPSTDVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKEVCRVRRPQYLMLFALQNCSFSTLKRPGSRMAGLL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0050793 (regulation of developmental process), GO:0065008 (regulation of biological quality), GO:0019222 (regulation of metabolic process), GO:0051240 (positive regulation of multicellular organismal process), GO:0050794 (regulation of cellular process), GO:0051239 (regulation of multicellular organismal process), GO:0051094 (positive regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0009892 (negative regulation of metabolic process), GO:0048522 (positive regulation of cellular process), GO:0009894 (regulation of catabolic process), GO:0045597 (positive regulation of cell differentiation), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:2000026 (regulation of multicellular organismal development), GO:0043487 (regulation of RNA stability), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0045595 (regulation of cell differentiation), GO:0031323 (regulation of cellular metabolic process), GO:0009895 (negative regulation of catabolic process), GO:0080090 (regulation of primary metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0051962 (positive regulation of nervous system development), GO:0043489 (RNA stabilization), GO:0043488 (regulation of mRNA stability), GO:0031330 (negative regulation of cellular catabolic process), GO:0060284 (regulation of cell development), GO:0010720 (positive regulation of cell development), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0050769 (positive regulation of neurogenesis), GO:0051960 (regulation of nervous system development), GO:0051252 (regulation of RNA metabolic process), GO:0031329 (regulation of cellular catabolic process), GO:0051253 (negative regulation of RNA metabolic process), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:0010468 (regulation of gene expression), GO:1902373 (negative regulation of mRNA catabolic process), GO:0048255 (mRNA stabilization), GO:0061013 (regulation of mRNA catabolic process), GO:1903312 (negative regulation of mRNA metabolic process), GO:1903311 (regulation of mRNA metabolic process), GO:1902369 (negative regulation of RNA catabolic process), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)