Protein: Myelin regulatory factor (A0A6Q8PHM1)
Organism: Homo sapiens (Human)
Subcellular location: Membrane; Single- pass membrane protein
InterPro domains:
- IPR025719: Myelin gene regulatory factor C-terminal domain 2 (domain) [806-939]
- IPR030392: Intramolecular chaperone auto-processing domain (domain) [376-485]
- IPR024061: NDT80 DNA-binding domain (domain) [39-330]
- IPR026932: Myelin gene regulatory factor, ICA domain (domain) [456-491]
- IPR051577: Myelin Regulatory Factor-like (family) [9-939]
- IPR037141: NDT80 DNA-binding domain superfamily (homologous_superfamily) [255-334]
- IPR008967: p53-like transcription factor, DNA-binding domain superfamily (homologous_superfamily) [130-329]
Sequence:
XLNCNNNNGMGAAPKPFPGGTGPPIKAEPKAPYAPGLPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPPQGPLSPGPGSLPLSIARVQTPPWHPPGAPSPGLLQDSDSLSGSYLDPNYQSIKWQPHQQNKWATLYDANYKELPMLTYRVDADKGFNFSVGDDAFVCQKKNHFQVTVYIGMLGEPKYVKTPEGLKPLDCFYLKLHGVKLEALNQSINIEQSQSDRSKRPFNPVTVNLPPEQVTKVTVGRLHFSETTANNMRKKGKPNPDQRYFMLVVALQAHAQNQNYTLAAQISERIIVRASNPGQFESDSDVLWQRAQVPDTVFHHGRVGINTDRPDEALVVHGNVKVMGSLMHPSDLRAKEHVQEVDTTEQLKRISRMRLVHYRYKPEFAASAGIEATAPETGVIAQEVKEILPEAVKDTGDMVFANGKTIENFLVVNKERIFMENVGAVKELCKLTDNLETRIDELERWSHKLAKLRRLDSLKSTGSSGAFSHAGSQFSRAGSVPHKKRPPKVASKSSSVVPDQACISQRFLQGTIIALVVVMAFSVVSMSTLYVLSLRTEEDLVDTDGSFAVSTSCLLALLRPQPPGGSEALCPWSSQSFGTTQLRQSPLTTGLPGIQPSLLLVTTSLTSSAPGSAVRTLDMCSSHPCPVICCSSPTTNPTTGPSLGPSFNPGHVLSPSPSPSTNRSGPSQMALLPVTNIRAKSWGLSVNGIGHSKHHKSLEPLASPAVPFPGGQGKAKNSPSLGFHGRARRGALQSSVGPAEPTWAQGQSASLLAEPVPSLTSIQVLENSMSITSQYCAPGDACRPGNFTYHIPVSSGTPLHLSLTLQMNSSSPVSVVLCSLRSKEEPCEEGSLPQSLHTHQDTQGTSHRWPITILSFREFTYHFRVALLGQANCSSEALAQPATDYHFHFYRLCD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0048519 (negative regulation of biological process), GO:0050793 (regulation of developmental process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0051241 (negative regulation of multicellular organismal process), GO:0051239 (regulation of multicellular organismal process), GO:0071704 (organic substance metabolic process), GO:0051093 (negative regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:2000026 (regulation of multicellular organismal development), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0051961 (negative regulation of nervous system development), GO:0045596 (negative regulation of cell differentiation), GO:0045595 (regulation of cell differentiation), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0050768 (negative regulation of neurogenesis), GO:0090304 (nucleic acid metabolic process), GO:0060284 (regulation of cell development), GO:0006259 (DNA metabolic process), GO:0051960 (regulation of nervous system development), GO:0010721 (negative regulation of cell development), GO:0006260 (DNA replication), GO:0014014 (negative regulation of gliogenesis), GO:0050767 (regulation of neurogenesis), GO:0000723 (telomere maintenance), GO:0050767 (regulation of neurogenesis), GO:0006261 (DNA-templated DNA replication), GO:0032200 (telomere organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0012505 (endomembrane system), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0005794 (Golgi apparatus), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)