Protein: V-abl Abelson murine leukemia viral oncogene homolog 1 (Mapped) (A6JU30)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR008266: Tyrosine-protein kinase, active site (active_site) [123-135]
- IPR001245: Serine-threonine/tyrosine-protein kinase, catalytic domain (domain) [6-256]
- IPR000719: Protein kinase domain (domain) [6-257]
- IPR050198: Non-receptor tyrosine kinases involved in cell signaling (family) [2-275]
- IPR015015: F-actin binding (domain) [762-888]
- IPR017441: Protein kinase, ATP binding site (binding_site) [12-35]
- IPR020635: Tyrosine-protein kinase, catalytic domain (domain) [6-257]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [5-262]
Sequence:
MERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKRGMRGAAGSTLQAPELPTKTRTCRKTAEQKDAPDALELLHTKGLGESDALDSEPAVSPLLPRKERGPPDGSLNEDERLLPKDKKTNLFSALIKKKKKMAPTPPKRSSSFREMDGQSERRGASEDDGREISNGPPALTSDAVEPTKSPKASNGAGVPNGAFREPGNSGFRSPHVWKKSSTLTSSRLAAAEEESGLSSSKRFLRSCSASCMPHGVRDTEWRSVTLPRDLPSAGKQFDSSTFGGHKSEKPALPRKRTSESRSEQVAKSTATPPPRLVKKTEEAAEDVFKDTESSPGSSPPSLTPKLLRRQVPASPSSGPSHKDEATKGNASGMGTPATAEPAAPSNKAGLSKASSEEPRARRHKHSSESPGRDKGRLSKLKPAPPPPPSSTGKAGKPAQSPSQDVAGEAGGATKTKCTSLSVDAVNSDPTKAGQPGEGLRKSVPPSVPKPQSATKPPGTPTSPVSTPSTAPAPSPLAGDQQPSSAAFIPLISTRVSLRKTRQPPERIASGTITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLESNLRELQICPATASSGPAATQDFSKLLSSVKEISDIVRR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0044877 (protein-containing complex binding), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0004672 (protein kinase activity), GO:0019899 (enzyme binding), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0019900 (kinase binding), GO:0051020 (GTPase binding), GO:0004713 (protein tyrosine kinase activity), GO:0031267 (small GTPase binding), GO:0019901 (protein kinase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0051130 (positive regulation of cellular component organization), GO:0031344 (regulation of cell projection organization), GO:0031346 (positive regulation of cell projection organization), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0010976 (positive regulation of neuron projection development), GO:0010975 (regulation of neuron projection development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0150034 (distal axon), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0044297 (cell body), GO:0030427 (site of polarized growth), GO:0098793 (presynapse), GO:0048471 (perinuclear region of cytoplasm), GO:0071944 (cell periphery), GO:0030054 (cell junction), GO:0044306 (neuron projection terminus), GO:0098794 (postsynapse), GO:0036477 (somatodendritic compartment), GO:0005737 (cytoplasm), GO:0120025 (plasma membrane bounded cell projection), GO:0043679 (axon terminus), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0005938 (cell cortex), GO:0043228 (non-membrane-bounded organelle), GO:0043025 (neuronal cell body), GO:0043197 (dendritic spine), GO:0097447 (dendritic tree), GO:0030426 (growth cone), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0099572 (postsynaptic specialization), GO:0043231 (intracellular membrane-bounded organelle), GO:0099091 (postsynaptic specialization, intracellular component), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0014069 (postsynaptic density), GO:0098978 (glutamatergic synapse), GO:0030425 (dendrite), GO:0043005 (neuron projection), GO:0098984 (neuron to neuron synapse), GO:0032279 (asymmetric synapse), GO:0099092 (postsynaptic density, intracellular component), GO:0005634 (nucleus), GO:0030424 (axon), GO:0044309 (neuron spine)