Protein: Spectrin beta chain (A6JQC5)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR002017: Spectrin repeat (repeat) [303-2096]
- IPR001849: Pleckstrin homology domain (domain) [2196-2308]
- IPR018159: Spectrin/alpha-actinin (repeat) [305-2162]
- IPR036872: CH domain superfamily (homologous_superfamily) [14-279]
- IPR001605: Pleckstrin homology domain, spectrin-type (domain) [2199-2299]
- IPR001589: Actinin-type actin-binding domain, conserved site (conserved_site) [56-154]
- IPR016343: Spectrin, beta subunit (family) [1-2363]
- IPR041681: Pleckstrin homology domain 9 (domain) [2200-2301]
- IPR001715: Calponin homology domain (domain) [54-278]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [2193-2310]
Sequence:
MTTTVATDYDNIEIQQQYSDVNNRWDVDDWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVARELEAESYHDIKRITARKDNVIRLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDEMKVLLLSQDYGKHLLGVEDLLQKHALVEADIAIQAERVRGVNASAQKFATDGEGYKPCDPQVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMSGRSGHFEQAIKEGEDMIAEEHFGSEKIRERISYIREQWANLEQLSAIRKKRLEEASLLHQFQADADDIDAWMLDILKIVSSNDVGHDEYSTQSLVKKHKDVAEEISNYRPTIDTLHEQAGALPQAHAESPDVKGRLAGIEERYKEVAELTRLRKQALQDTLALYKMFSEADACELWIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHSGHPSEKEIRAQQDKLNTRWSQFRELVDRKKDALLSALSIQNYHLECNETKSWIREKTKVIESTQDLGNDLAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRLAEISDVWEEMKTTLKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENIKNEIDNYEEDYQKMRDMGEMVTQGQTDAQYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQQFLRDTKQAEAFLNNQEYVLAHTEMPTTLEGAEAAIKKQEDFMTTMDANEEKINAVVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNREAASELLMRLKDNRDLQKFLQDCQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISEKPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYGKDLTSVNILLKKQQMLENQMEVRKKEIEELQSQAQALSQEGKSTDEVDSKRLTVQTKFMELLEPLNERKHNLLASKEIHQFNRDVEDEILWVGERMPLATSTDHGHNLQTVQLLIKKNQTLQKEIQGHQPRIDDIFERSQNIITDSSSLNAEAIRQRLADLKQLWGLLIEETEKRHRRLEEAHKAQQYYFDAAEAEAWMSEQELYMMSEEKAKDEQSAVSMLKKHQILEQAVEDYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLYAGLKDLAEERRGKLDERHRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVDTVNHMADDLINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKEIFGRIQDKHKKLPEELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADDIQKRENEVLEAWKSLLDACEGRRVRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTACIELGKALLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWDERFSALERLTTLELLEVRRQQEEEERKRRPPSPEPSAKVSEEAESQQWDTSKGDQVSQNGLPAEQGSPRMAGTMETSEMVNGAAEQRTSSKESSPVPSPTSDRKAKSALPAQSAATLPARTLETPAAQMEGFLNRKHEWEAHNKKASSRSWHNVYCVINNQEMGFYKDAKSAASGVPYHSEVPVSLKEAICEVALDYKKKKHVFKLRLSDGNEYLFQAKDDDEMNTWIQAITSAISSDKHDTSASTQSTPASSRAQTLPTSVVTITSESSPGKREKDKEKDKEKRFSLFGKKK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0022406 (membrane docking), GO:0007267 (cell-cell signaling), GO:0051641 (cellular localization), GO:0065008 (regulation of biological quality), GO:0042221 (response to chemical), GO:0032879 (regulation of localization), GO:0140029 (exocytic process), GO:0050794 (regulation of cellular process), GO:0051234 (establishment of localization), GO:0051716 (cellular response to stimulus), GO:0140352 (export from cell), GO:0007154 (cell communication), GO:0051640 (organelle localization), GO:0006904 (vesicle docking involved in exocytosis), GO:0099536 (synaptic signaling), GO:1903530 (regulation of secretion by cell), GO:0051049 (regulation of transport), GO:0070887 (cellular response to chemical stimulus), GO:0006810 (transport), GO:0051649 (establishment of localization in cell), GO:0140056 (organelle localization by membrane tethering), GO:0001505 (regulation of neurotransmitter levels), GO:0032940 (secretion by cell), GO:0060627 (regulation of vesicle-mediated transport), GO:1901700 (response to oxygen-containing compound), GO:0010033 (response to organic substance), GO:0023061 (signal release), GO:0006836 (neurotransmitter transport), GO:0099504 (synaptic vesicle cycle), GO:0097305 (response to alcohol), GO:0006887 (exocytosis), GO:0071310 (cellular response to organic substance), GO:0099643 (signal release from synapse), GO:0099537 (trans-synaptic signaling), GO:0017157 (regulation of exocytosis), GO:0046903 (secretion), GO:0051046 (regulation of secretion), GO:0007269 (neurotransmitter secretion), GO:0016192 (vesicle-mediated transport), GO:1901701 (cellular response to oxygen-containing compound), GO:0016079 (synaptic vesicle exocytosis), GO:0048278 (vesicle docking), GO:0098916 (anterograde trans-synaptic signaling), GO:0045471 (response to ethanol), GO:0099003 (vesicle-mediated transport in synapse), GO:0097306 (cellular response to alcohol), GO:0045055 (regulated exocytosis), GO:1903305 (regulation of regulated secretory pathway), GO:0017158 (regulation of calcium ion-dependent exocytosis), GO:0007268 (chemical synaptic transmission), GO:0071361 (cellular response to ethanol)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0098794 (postsynapse), GO:0036477 (somatodendritic compartment), GO:0030054 (cell junction), GO:0043197 (dendritic spine), GO:0099571 (postsynaptic cytoskeleton), GO:0120025 (plasma membrane bounded cell projection), GO:0097447 (dendritic tree), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0043228 (non-membrane-bounded organelle), GO:0043005 (neuron projection), GO:0098871 (postsynaptic actin cytoskeleton), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0098978 (glutamatergic synapse), GO:0030425 (dendrite), GO:0005856 (cytoskeleton), GO:0044309 (neuron spine), GO:0015629 (actin cytoskeleton)