lokahq/bioreason-rl huggingface dataset:
Protein: Ras GTPase-activating protein-binding protein 1 isoform X1 (A0A8M2BKD5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [278-441]
- IPR034374: G3BP1, RNA recognition motif (domain) [348-427]
- IPR002075: Nuclear transport factor 2 domain (domain) [11-133]
- IPR039539: Ras GTPase-activating protein-binding protein (family) [7-454]
- IPR000504: RNA recognition motif domain (domain) [351-426]
- IPR032710: NTF2-like domain superfamily (homologous_superfamily) [4-133]
- IPR018222: Nuclear transport factor 2, eukaryote (domain) [7-135]
- IPR035979: RNA-binding domain superfamily (homologous_superfamily) [346-454]
Sequence:
MVMEKPSAQLVGREFVRQYYTLLNQAPDYLHRFYGKNSSYVHGGLDNNGKPAEAVYGQSEIHKKVMALSFRDCHTKIRHVDAHATLNEGVVVQVLGELSNNMQPMRKFMQTFVLAPEGTVANKFYVHNDIFRYQDEVFGDSDSEPPEESEEDVEELERVHSPEVVQEESSGYYEQTPCVEPEVPQEEVSVTPEPQPEPEVEVEPEPAAVELKAEPISQPEVHVEEKTQRSPPSPTPADTAPTMPEDNRPSSWASVTSKNLPPGGVVPATGVPPHVVRVPSAQPRVEVKTETQTTAQRPQRDQRPRDQRPGPSPAHRTPRPGGVQNSNELMVREGESGESEVRRTVRYPDSHQLFVGNVPHDVDKNELKEFFEQYGTVLELRINSGGKLPNFGFVVFDDSEPVQKILNNRPIKLRGDVRLNVEEKKTRSAREGDRRDIRPRGPGGPRDRIGGSRGPPTRGGMAQKPSFGAGRGTGPSEGRYTGPRQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023057 (negative regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0010646 (regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0030111 (regulation of Wnt signaling pathway), GO:0030178 (negative regulation of Wnt signaling pathway), GO:0090090 (negative regulation of canonical Wnt signaling pathway), GO:0060828 (regulation of canonical Wnt signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0043229 (intracellular organelle), GO:0035770 (ribonucleoprotein granule), GO:0036464 (cytoplasmic ribonucleoprotein granule), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle)
Protein: RNA helicase (A0A8M9Q4N5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm
InterPro domains:
- IPR001650: Helicase, C-terminal domain-like (domain) [593-754]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [315-759]
- IPR011545: DEAD/DEAH-box helicase domain (domain) [379-569]
- IPR014014: RNA helicase, DEAD-box type, Q motif (domain) [355-383]
- IPR000629: ATP-dependent RNA helicase DEAD-box, conserved site (conserved_site) [524-532]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [374-597]
Sequence:
MSHVVVDGSHGLDQQLAVLDLNSADGQGVGTGRRYIPPHLRNKDASKNAGNAYSSGRQSGYSVAPVQSFSPKQYPQSWHPEGNQRHRQNYPTGWNDFRTGNYLEKADLLLRSSICEGMVVLSALYFCLGSQRFASQELAFYHTYTSGWPDRCASPARTDSSVATDGNEDTASVISWADRCDSPGWDGSRTNGFVNGYHDSRMNGTANFARGPLRNDRGGRGGFRGNRNGASFNQPVHNAGYGTYENKDGGWNSVVNRDAYASFGGRSDRGKSAFFNDRGASSRGRYERGGFGGGTGGNSRWVEESRDEEDWSKPMPPNERLEHELFSASNTGINFEKYDDIPVEATGTNSPGHIESFHDVDMGEIIMGNITLSRYTRPTPVQKYAIPIIKTKRDLMACAQTGSGKTAAFLLPVLSQIYSEGPGEALQATKASTQENGKYVRRKQYPISLVLAPTRELALQIYDEARKFAYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDYCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGSRQTMMFSATFPKEIQILARDFLEEYIFLAVGRVGSTSENITQKVVWVEENDKRSFLLDLLNATGKDSLTLVFVETKKGADALEDFLYREGYACTSIHGDRSQRDREEALHQFRSGRCPIMVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFYNDKNSNITKDLLDILVEAKQEVPSWLENLAYEHQHKSTNRGRPKRFSGGFGARDYRQMPGGGNTFGNRGARNTGGHGGNRGFGGNKGGFGSFGGDSYGGTYGNYGGNYTQVDWWGN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0048870 (cell motility), GO:0042221 (response to chemical), GO:0050900 (leukocyte migration), GO:0042330 (taxis), GO:0097529 (myeloid leukocyte migration), GO:0006935 (chemotaxis), GO:0030595 (leukocyte chemotaxis), GO:0070887 (cellular response to chemical stimulus), GO:0016477 (cell migration), GO:0071621 (granulocyte chemotaxis), GO:0060326 (cell chemotaxis), GO:0097530 (granulocyte migration), GO:1990266 (neutrophil migration), GO:0030593 (neutrophil chemotaxis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0043229 (intracellular organelle), GO:0035770 (ribonucleoprotein granule), GO:0036464 (cytoplasmic ribonucleoprotein granule), GO:0045495 (pole plasm), GO:0043228 (non-membrane-bounded organelle), GO:0043186 (P granule), GO:0060293 (germ plasm), GO:0043232 (intracellular non-membrane-bounded organelle)
Protein: Protein tyrosine phosphatase, receptor type, E, b isoform X2 (A0A8M6Z283)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane; Single-pass type I membrane protein
InterPro domains:
- IPR029021: Protein-tyrosine phosphatase-like (homologous_superfamily) [43-631]
- IPR016336: Receptor tyrosine-protein phosphatase, alpha/epsilon-type (family) [6-632]
- IPR000242: Tyrosine-specific protein phosphatase, PTPase domain (domain) [71-623]
- IPR000387: Tyrosine-specific protein phosphatases domain (domain) [251-612]
- IPR016130: Protein-tyrosine phosphatase, active site (active_site) [270-570]
- IPR003595: Protein-tyrosine phosphatase, catalytic (domain) [229-620]
- IPR050348: Protein-Tyrosine Phosphatase (family) [42-431]
Sequence:
MRKTFRFWFREQRKDLVTSVDKKLPNGFLEDQEQTVVLLPRSPSPSKRYFPIPLDSLEEEFRLRMADDGKLFREEFNSLPCGFGCGTFEEASREENREKNRYPNILPYDHSRVLLSHIDGYMGSDYINASYIDGYREKNKFIAAQGPKPETVGDFWRMVWEHKCATIVMLTNTRERKEEKCYQYWPEQGCWIYGCVRVAMEDFTVLVDYTIRKFCVQHHAAEGCRPPRLVTQLHFTSWPDFGVPLSPIGMLKFLKKVKSVNPAHAGPIIVHCSAGVGRTGTFIVIDAMMDMMHAEGRLDVFGFVSRIRKQRCQLIQTDMQYSFIYQALLEHYLFGDTELDIASLEGHLHKLHNTHTNMDRVGLEEEFRKLTNVRIMKENMRTGNLPANMRKNRVLQIIPYDFNRVILSMKRGQEFTDYINASFIDGYRQKDYFIATQAPLAHTVQDFWRMVWEWKCHSIVVLTELKEREQEKCVRYWPAEGSVSFGDYVLELKRDTLCETFSIRDMLLSYASEKQTRLVRQFHFHGWPEIGIPSDGKGMIDIIAAVQKQQQQSGNNPIVVHCSAGAGRTGTFIALSNILERVKAEGLLDVFQTVKSLRTQRPHMVQTVEQYDFCYRVVQDFVDIYSDYANFK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0004721 (phosphoprotein phosphatase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0004725 (protein tyrosine phosphatase activity), GO:0016791 (phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009888 (tissue development), GO:0009790 (embryo development), GO:0048598 (embryonic morphogenesis), GO:0048729 (tissue morphogenesis), GO:0060429 (epithelium development), GO:0007369 (gastrulation), GO:0060027 (convergent extension involved in gastrulation), GO:0002009 (morphogenesis of an epithelium), GO:0060026 (convergent extension)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Voltage-gated potassium channel subunit beta-1 (A0A8M2B927)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side
InterPro domains:
- IPR023210: NADP-dependent oxidoreductase domain (domain) [139-441]
- IPR005400: Potassium channel, voltage-dependent, beta subunit, KCNAB1 (family) [343-440]
- IPR005983: Potassium channel, voltage-dependent, beta subunit, KCNAB (family) [124-442]
- IPR036812: NAD(P)-dependent oxidoreductase domain superfamily (homologous_superfamily) [123-448]
- IPR005399: Potassium channel, voltage-dependent, beta subunit, KCNAB-related (family) [85-454]
Sequence:
MFATHRSSLTELRVGHTGRRLSRQHSVPSEQVPKNGPPGNSVRRSSSISSSKLLSLSFSESMRSDIDRYLSDQGLYPLRQGGGEMGEIRSLREVRAAAQLKNLEDFLRSNGVSLQESISFQTGMRYRNLGKSGLRVSCLGLGTWVTFGGQITDEIAEQLMTLAYENGINLFDTAEVYAAGKAEMVLGSIIKKKGWRRSSLVITTKIYWGGKAETERGLSRKHIIEGLRASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLIPPVCEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIISGKYDSGVPPCSRASLKGYQWMKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSCVLLGASSTDQLMENIGAIQVLPKLSSSIIHEVDSILGNKPYSKKDYRS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0016247 (channel regulator activity), GO:0005515 (protein binding), GO:0099106 (ion channel regulator activity), GO:0015459 (potassium channel regulator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0065008 (regulation of biological quality), GO:0098900 (regulation of action potential), GO:0051239 (regulation of multicellular organismal process), GO:0050794 (regulation of cellular process), GO:0010646 (regulation of cell communication), GO:0042391 (regulation of membrane potential), GO:0044057 (regulation of system process), GO:0051969 (regulation of transmission of nerve impulse), GO:0031644 (regulation of nervous system process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:1990351 (transporter complex), GO:0098797 (plasma membrane protein complex), GO:1902495 (transmembrane transporter complex), GO:0005886 (plasma membrane), GO:0034702 (ion channel complex), GO:0008076 (voltage-gated potassium channel complex), GO:0034703 (cation channel complex), GO:0034705 (potassium channel complex)
Protein: RAS guanyl-releasing protein 1 isoform X1 (A0A8M2BLA4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR036964: Ras guanine-nucleotide exchange factor, catalytic domain superfamily (homologous_superfamily) [186-455]
- IPR002219: Protein kinase C-like, phorbol ester/diacylglycerol-binding domain (domain) [536-586]
- IPR008937: Ras-like guanine nucleotide exchange factor (family) [51-434]
- IPR001895: Ras guanine-nucleotide exchange factors catalytic domain (domain) [194-430]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [476-488]
- IPR011992: EF-hand domain pair (homologous_superfamily) [453-524]
- IPR000651: Ras-like guanine nucleotide exchange factor, N-terminal (domain) [49-174]
- IPR002048: EF-hand domain (domain) [463-498]
- IPR023578: Ras guanine nucleotide exchange factor domain superfamily (homologous_superfamily) [53-455]
- IPR020454: Diacylglycerol/phorbol-ester binding (domain) [534-587]
- IPR046349: C1-like domain superfamily (homologous_superfamily) [524-586]
Sequence:
MGFDTMNRKESKSSRKSRQEGGIKSRRPVQRRMTCPSAQEISRALQSPPAHASFRSASLDELILRCLHCFDSDGKLNRGTQLVSMTLMMHNWVVPSHIFAHKLLSLYKDCPAEKRGQRRPQICHFIRQWISQFRLMFEMDPLLEKAMGDLWALVSAEGTNSHHQLINTPYINPPVNISQTPSPLVKKRKVSLLFDHMEPDEMAEHLSYLEFKNFCNVSFLDYRSYVVHGSVRDNPALERSVMLCNGVSQWVQLMILNRHTSQQRAEVFTKFIHVAQKLRSLQNFNTLMAVIGGLCHSSISRLKDTASLLSSDVTKTLSELTELLSSYSNYSNYRRVYSECTGFKVPILGVHLKDLISLNEALPDYLEDDKINLGKLQHLYSNISDLLAIHDCTPPFEANKDLLHLLTLSLDLYYTEDEIYELSYAKEPKNPKIQPVAPVKPPVVAEWGSGVTPRLDPATISKHVKQMVDSIMKNYDLNMDGYISLEEFEKIAANFPFSFCTHESDREGEISREEITSYFMRGMSVCAKLGFNLHNLHNFHETTYKRPTFCDTCGGFLWGVIKQGYHCKDCGVNCHKHCKDVVGMECLKRLQVNSSSCPCTPGPVSGLHTKGNSWSEFSQSFQSGSEEEAFVFPNGNESEHSKGQTSSDSDAEAATLSDRSTQTEPGVWTPVAKRKDRLHSQKQHPPLEKSATLPARVRGSSAPSSLLQEKMDELKLNKDKRKEPD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0140678 (molecular function inhibitor activity), GO:0060589 (nucleoside-triphosphatase regulator activity), GO:0005085 (guanyl-nucleotide exchange factor activity), GO:0030695 (GTPase regulator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0001945 (lymph vessel development), GO:0048731 (system development), GO:0001944 (vasculature development), GO:0072359 (circulatory system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Catenin delta-2 isoform X1 (A0A8M3B7R3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
Sequence:
MPVPDQPSGTENSSMLSPVLNASNGDGSETETTSAILASVKEQELQFERLTRELEAERQIVATQLERCKLGSETGSMSSISSADEKFRWNNQDGQKDIEEELTTGLELVDSCIRSLQESGILDSQEFTAGERPGILSQSALQLNNQEGTFPYPVSYHSNQTLALGDLSASQPPRSGQVGGALHSYNQVTSNRVAQLAARETAARAHSRDSYAQSHGSAFHMPDDQPTVPVNYSCATLPAQRVSSPFSMQALGSPSKLQRLGSASDMPSYATLARVSSPKQSPSRLAKSYSTSSPINMAAGGGSSSSPLHMAGAGNVSNSSPLHQLSAAVGSYATLSPTKRMLHTTDQYKISHDLYANATLQRPGSLAGSRGSYSSQHSHLGSELRPLQSPEHHIDPIYEDRVYQKAPLRNFNQAQDPMNQFCDQVLNFLLCPYSPVIAPSSPGVDSIPLQRTGSQNATGTFPRAGYATGPGASTADYANPYRTLQFCPSTDSPYSKSGPALPPEATLVRSPSVDSIQKDPRYDPEFLVWNQNQAEQRMTKEFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKSEIRRQGGIQLLVDLLDHRMTDVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDVEIRELLTGVLWNLSSCDALKMPIIQDALAVLTNTVIIPHSGWDTSPLQDDRKLHLHSSQVLRNATGCLRNVSSAGEEARRRMRECEGLTDALLYVIQTALGTSEIDSKTIENCVCILRNLSYRLAAETSQGQQMGSEELDGVLCTDASGKDAESSGCWGKKKKKKKSHDQWDGVGPFPDSSDPPKGLQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKVGPTLKPWSVYIRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNNNSTGTGGSSKSMSDDTITAICCALHEVITKNMENTKALRDAGGIEKLIGIARSKGDKHTPKVVKAASQVLNSMWQYRDLRSLYKKDGYSQYHFVGSSSTIERDRQRPYSSSRTPSISPVRTSPNNRSASAPTSPREMMSLKERKTDYESTGSNSTYHGNKGEHTSRKDAMAAQISSGTSTLFRGAYMSPADDIKHNQVSAQGNPPEAYPPFQTPPGANFEEPYYEDQAHKRPPPAADGTMHLGLKSTGNYVDFYSASRPYSELNYETSHYPASPDSWV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048870 (cell motility), GO:0030154 (cell differentiation), GO:0016477 (cell migration), GO:0048731 (system development), GO:0001764 (neuron migration), GO:0022008 (neurogenesis), GO:0007399 (nervous system development), GO:0048699 (generation of neurons)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction), GO:0070161 (anchoring junction), GO:0005911 (cell-cell junction), GO:0005912 (adherens junction)
Protein: Paired mesoderm homeobox protein 1 isoform X2 (A0A8M6YUR5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
- IPR017970: Homeobox, conserved site (conserved_site) [129-152]
- IPR003654: OAR domain (domain) [243-259]
- IPR001356: Homeodomain (domain) [94-158]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [92-159]
- IPR043378: Paired mesoderm homeobox protein 1/2 (family) [3-267]
Sequence:
MTSSYAHVMDRQATISSRLESPITANLENLQAKKNFSVSHLLDLEEAREMVGSQVDESVGETGRTMLESPGLTSGSDTTQQENEQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERAMLASKNASLLKSYSGDVTAVEQPIVPRPAPRPNDYLSWGSAAPYSWYPRPEGGPMRVPQKMLPTESNTMATYPPTCANTTSTQGMNMANSIANLRLKAKEYNLNQVPTVN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0009893 (positive regulation of metabolic process), GO:0019222 (regulation of metabolic process), GO:0048856 (anatomical structure development), GO:1904888 (cranial skeletal system development), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010628 (positive regulation of gene expression), GO:0010468 (regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Voltage-dependent L-type calcium channel subunit beta-1 (A0A8M2BAY4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Membrane; Peripheral membrane protein
InterPro domains:
Sequence:
MVQEGNMSRTPSTSTQEIQMDMFDHHGSHAQGKYAKRKSRFKRSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDPEALRKEADRQALATLEKAKTKPVAFAVRTNVGYNPGPNDDVPVQGMAISFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLESTRQLQEQRMRQNRLSSSKSGGSSSLDVATGARRPTPPGTADLSSGLYDDALDSDVEEAETADTRDHKGVGGSVTSPQGNLPRLPFFKKMEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHKFEGRISITRVTADISLAKRSVLNNPSKHTIIERSSTRSSLDLLAEVQSEIERIFELARTLQLVALDADTINHPSQLAKTSLAPIIVYIKIASPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDIILDENQLEDACEHLAEYLEAYWKATHPPSSNPPNPLLNRTMATAALAASPEPVSNLQGPFLVHGEQKREMPERGGLQDYQSDLSGKQPLRSSRSQLQTGSRGLSRQDTFDSETQGSRDSAYTDDMETDPYEEPDPCRSYRLNPAHHAPRQASWEDEGAEPDQENLNMVPPPANQHQRGRGKLRERYCQDAEAGGATTGRNHNQEEWSRDVYIR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0046907 (intracellular transport), GO:0051668 (localization within membrane), GO:0045184 (establishment of protein localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0006886 (intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0008104 (protein localization), GO:0006811 (monoatomic ion transport), GO:0015031 (protein transport), GO:0090150 (establishment of protein localization to membrane), GO:0072657 (protein localization to membrane), GO:0006816 (calcium ion transport), GO:0006612 (protein targeting to membrane), GO:0006812 (monoatomic cation transport), GO:0006605 (protein targeting), GO:0030001 (metal ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:1990351 (transporter complex), GO:0098797 (plasma membrane protein complex), GO:1902495 (transmembrane transporter complex), GO:0005886 (plasma membrane), GO:0034702 (ion channel complex), GO:0005891 (voltage-gated calcium channel complex), GO:0034703 (cation channel complex), GO:0034704 (calcium channel complex)
Protein: Thrombopoietin receptor isoform X1 (A0A8M2BDQ1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR003961: Fibronectin type III (domain) [154-434]
- IPR013087: Zinc finger C2H2-type (domain) [9-30]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [60-436]
- IPR015152: Growth hormone/erythropoietin receptor, ligand binding (domain) [51-149]
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [61-430]
Sequence:
MSPPTVPTCLSECASVFALAVSDKQHSDRHEGRRSHETFVKNTTVNSEPRQPKPELLAMDEDPKCFTRNLEDFTCFWDAPVEKSYDFLYIIEGLMEEKRCDVKQQTFKEKILNICTFPPSDVYLYVETHIRVIDKDTNTTIYSRAVSVEDQLLLYPPSNISLHPTEEVGQMLVKWKRSSNEHEIRYSFKNTSTVKSVSENDYKLVSLVPGENCTVQMRVKPSGDFKRFWSDWSNPVTAMVPQTAGDIEFRCHTSDLIQIICKWRGDLYKDNTYSFYYKQLNRSSWSSWKLCPNCNNSIHQCVLYGQKSNVFKFYLNTGLQPFSRTFYAETFYMNSKVQTRPPEGLKVQIGEERLCLTWDSPFLIISKHLMYQIRYQHHEENQWKGFKASGSKTSTCLDVHRGGRYTIQVRAQPNGSVYSGNWSDWSKPVTTNLPLSKEWIIFVCIPVALIIIATAVISFFSRYFRKVKRSLWPPVPNLNKVLENILTDISGSHWEPTFNIKQCDDDTATSVVEVLTEGESAVKTCKNTCPLLSEHSEKHGEHFREDLEMAQDYVILNNNIIPCLTGNDYVYKDVASTHLANEKQHSCSSTSYTSLPDHTTDILNQSYLLLAEQSDLGAYQTTCGQYTNLEITAVSCVAIGE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019838 (growth factor binding), GO:0019955 (cytokine binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0030154 (cell differentiation), GO:0048468 (cell development), GO:0030097 (hemopoiesis), GO:0030099 (myeloid cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)