lokahq/bioreason-rl huggingface dataset:
Protein: Collagen alpha-1(XIV) chain isoform X3 (A0A8M9P888)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
Sequence:
MQVSGSRIKLWCPLISLALIQFLAPVSAQGGETSELQIAKGVNKAIIKEFNPRKEYSVKVIAVSGNLQSRALQGKYTEDQSSDGEITQPQRLKEPGAVEEGNEISAVDQFVCTTPAIADIVILVDGSWSIGRINFRLVRMFLENLVNAFDVGIDKTRIGLAQYSGDPRIEWHLNGFSTKEAVIDAVKNLPYKGGNTLTGLALTYVLENSFKPESGARDNIPKIGILITDGKSQDDVISPAQTLRSSGVELFAIGVKNADENELKAIASEPEDTHVYNVADFSIMGTIVEGLTRTVCDGVEQQDKEIKQDSVPEETVSTPLNLLISEVTAHSFRVSWTHSAGKVEKYRVVYHPTDADIPEEIVVGGLENSVVLQNLNSLTEYEIAVFAVYRSAASDALRGSEITQALPTVSDLELYDVTDSSMRARWRDAEGASGYMILYAPLSSDTPDERELKVDETVTDVELTGLIPDTEYTVTVYATFGEEASDPATVQETTMSLKPPRNLRVTEVDHSSVRLNWDSASSKVKGYQVIYVKTDGVQTNQVELGPVTNVYLKNLSPLTEYTVAVFAVYDGGQSEALSGGFSTKLVPAPFSLMTSDVTSESFQVSWSHPARDVVLYKLIWSPTAGRDEREVMLAGDTDSYVIQDLSPFTEYKVSLAAIYKDETESSPVVVLEYTLGWTTEFPTTIPTTTPIFHQGVTNLWIDEETPFSIQVNWEVQDSDVDQYKVTYVSTDRTEETVLVSGNRRNVVLQPLLSDTKYKITVTPVYADEESSQLSMSSFGTTLPLSGPSNLRVSDEWYNRFRISWDSPQFPTMGYRVIYQPISVSGRALETFVGDDVNTLLILNLLSDTEYSVQVIASYTTGSSQPLTAKGKTLFLGVRNLNTYQVLSSSVCAQWQPHRHASVYRVVIESLHNGQKQEVRVGGGASRECFFRLSPNTQYKISVYTVLQDTEGPAVTTMVTTALAPTQPPTAAPTTSPPPTIPPAKEVCKAAKADLTFLVDGSWSIGDDNFQKIIRFLYSTTGALDVIGPEGTQVAIAQFSDDARTEFKLNSYSDKEALLDAVQRISYKGGNTKTGRAIKHVKEAIFSEDAGVRRGIPKVLVVLTDGRSQDDVNKISKEMQMEGYIIFAIGFADADYGELVNIASKPSERHVFFVDDLDAFKKIEEQLITFVCEAATATCPSVLMSGNTLAGFRMMEMFGLAEKHYSSVQGVSMEPGTFNSFPCYRLHKDALVSQPTRYLHPEGLPSDYTISMLFRILPETPQEPFALWEILDKNNEPLVGIILDNGGKTLTFFNSDYKGEFQTVTFEGPEIKKIFYGSFHKLHVAISKTAAKVVIDCKTVGEKSINAAGNISIDGVEVLGRMVRSRGRKDNSAPFQLQMFDIVCSTSWASRDKCCELPGLRVEEDCPAMPHACTCAQDSKGPPGPSGPPGGPGIRGSRGDRGEPGLTETAGHSHFVSAARLVGSQGLPGEIGPPGPQGPPGPQGPNGLSIQGPPGAPGEKGDKGEIGLPGPQGVPGANGGPGRDGPPGQRGLPGKDGPQGRQGPPGPMGSPGAPGAPGSNGPPGQLGDQGPPGPAGTKGERGERGDMQSHAAVRAIARQVCEQLIQSHLSRYNSILNQIPSQSVSVRTVPGPPGEPGRPGLQGPQGEQGPPGRPGFPGASGQNGRPGERGLPGERGEKGSPGVGTQGPRGPPGSPGPAGEGRTGSQGPPGRPGIQGTQGRPGTPGSPGPAGPPGYCDQNSCLGYNVGVQQLSSNPYQNYGPATNYNPEDEEEDDPYGGYRAYPPQYYQPSYPDPRGARPGPVHPGDTAGMRAPGARRFTRSTAEEGIVHQPQEHVKEEELW
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0045229 (external encapsulating structure organization), GO:0043062 (extracellular structure organization), GO:0022607 (cellular component assembly), GO:0030198 (extracellular matrix organization), GO:0085029 (extracellular matrix assembly), GO:0071711 (basement membrane organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062023 (collagen-containing extracellular matrix)
Protein: Bromodomain-containing protein 8 isoform X4 (A0A8M2B380)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR037966: Brd8, Bromo domain (domain) [664-767]
- IPR036427: Bromodomain-like superfamily (homologous_superfamily) [630-778]
- IPR001487: Bromodomain (domain) [660-768]
Sequence:
MSTGMGKHKMLSLGPTEPWSIREKLCLASSVMRSGDQNWVSVSRAIKPFSESGRPPDWFSQKHCASQYSQLLETTEAPKRKRGEKGEVVETIEDVIVRRLTAERIEELKRLIKDTQEKYRKLKKEVDLIQAGHVDPKLEELWAEIELKKKQEEEEAEQKKRATEAAYQIRQAAKNTPKRVPSVTVRSPPGASSPSMDILQPDASQPMTDESCASPMAQGVTVFMPVSDVMGPGPKESGLSSLVDDSPQKKHLAPKATPPPSPLLSELLKKGSLIAASSRLVVEGEVATGLSNGSHAVELHTSATVLPATQDITADAPTLSRLLESVTPAQQPVSADPPKPPTVVPPAPDHLSVPKSGDAAIAEGSGAEAVMAGSSTPAEVEGKETELVEEDTVVSVSYMGHELDLETVGDIIAIIEEKVDDPVEALDAAAVEAALSLCEDPAVGGHPLTSPWESQTFKAAEPEPMIQQSAIPAGAESAPNSAIVQGEMEVLVEEATETEAVEGVTEEPEVPSAPETEQSQDSEVKTEVERGGEGEGGVEETAQPENRTPSPAVKCEGEDWVQPETVTPCLDSEDSSASAKDAKEVKEEDGGSEVDVDEGMEMKECGDGDGEGPYLSEVDPPASESEDGYGSHSQRYTTADSTASSPASSQFSMCSEDQEALQAQKIWKKAIMLVWRAAANHRYASVFLQPVSDDIAPGYHSIVHRPMDLSAIKKNIESGQIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMALEMQRDVLEQIQQFLATQLIMQTSESGISTKSLRGREANRKQDPNEKDSLSMASPAFLLSLFDGGTRGRRSAIEADMKMKK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0030154 (cell differentiation), GO:0048468 (cell development), GO:0002244 (hematopoietic progenitor cell differentiation), GO:0030097 (hemopoiesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Protein numb homolog isoform X3 (A0A8M2BH67)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Plays a role in the process of neurogenesis
InterPro domains:
- IPR010449: NUMB domain (domain) [251-331]
- IPR016698: Numb/numb-like (family) [1-618]
- IPR006020: PTB/PI domain (domain) [34-164]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [3-163]
Sequence:
MNKLRQSFRRKKDVYVPESSRPHQWQTDEEAVRGGKCSFAVKYLGHVEVEESRGMHICEDAVKKLKTAGKKAVRAVLWVSADGLRVVDDKTKDLILDQTIEKVSFCAPDRNFEHAFSYICRDGTTRRWICHCFMAIKDSGERLSHAVGCAFAACLERKQKREKECGVTATFDANRTTFTREGSFRVTTATEQAEREEVMRQLQDNKKDSDLVISSSSGGSCNPVVVTLAGPNGSSSPPLPMAPLGLQDGNPHVIPRRHAPVEALARQGSFRGFPALSQKTSPFKRQMSLRMNELPSTMQRKSDFPIKNTVPEVEGEVDSISSLCTQITSTFSGPPEDPFSSAPMPKPASSPQSPAAPGSEWPSPSPSTGALPAVSATLSTPTSAHKRTPSEADRWLEEVTKSVRAHQPASTARTSTPPAQQPFPAPVPVPLPPSAPFMPPIPPSAVPSVPPRQPAFHAQAPVSFPVSNGIPYAQPTFPIVGITPSQMVANVFGSATQTQPISVPVPVAQTQLQSSPFSTPPATQFEPQPVCSPFGKPLLPPVPNTVVLQPPPKPSPAFNGANSWAAAASAGQAGANPPQADAFEAQWAALESRSQQRTAPSPTNPFSSELHKTFEIQL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008013 (beta-catenin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0042592 (homeostatic process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048871 (multicellular organismal-level homeostasis), GO:0002262 (myeloid cell homeostasis), GO:0007389 (pattern specification process), GO:0009799 (specification of symmetry), GO:0009790 (embryo development), GO:0034101 (erythrocyte homeostasis), GO:0003002 (regionalization), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048513 (animal organ development), GO:0048872 (homeostasis of number of cells), GO:0030097 (hemopoiesis), GO:0009855 (determination of bilateral symmetry), GO:0048568 (embryonic organ development), GO:0030218 (erythrocyte differentiation), GO:0060972 (left/right pattern formation), GO:0030099 (myeloid cell differentiation), GO:0007368 (determination of left/right symmetry), GO:0035162 (embryonic hemopoiesis), GO:0060319 (primitive erythrocyte differentiation), GO:0060215 (primitive hemopoiesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0045178 (basal part of cell), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0009925 (basal plasma membrane), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0016323 (basolateral plasma membrane)
Protein: Proton myo-inositol cotransporter isoform X2 (A0A8M2BAJ5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR020846: Major facilitator superfamily domain (domain) [38-550]
- IPR005829: Sugar transporter, conserved site (conserved_site) [334-350]
- IPR005828: Major facilitator, sugar transporter-like (family) [39-561]
- IPR050814: Myo-inositol Transporter (family) [25-564]
- IPR036259: MFS transporter superfamily (homologous_superfamily) [24-567]
- IPR003663: Sugar/inositol transporter (family) [33-497]
Sequence:
MEDQRAYARVEDESTLIKTASKRDHELQPGPPCFVYTLAFFSALGGFLFGYDTGVVSGAMLLLKREKKLSSVWQELLVSITVGAAAVSALAGGFLNGRFGRRVCILLASFIFCAGGIILSVARNKEALLCGRLTVGLGLGIASMTVPVYIAEVSPPDLRGQLVTVNTLFITGGQFIASVVDGAFSYLPHDGWRFMLGLSVVPAALQFLGFLFLPESPRWLLQKGFTQNALLVLRQIRGDVDVEEEFESIRCSIQEEQRDVAGGPVLWRMLASPPARRALIVGCGLQMFQQLAGINTVMYYSATILQMSGVQDDQMAIWLAAGTAFTNFLFTLVGVWLVERVGRRRLTMASLLGTAVSLMVLAAGFLLSAQASPPVTFHPSNPSIHNSTCGNYGFCESCMLDPDCGFCYGLNATAVVQSSCVPVDPANTETAALGRCFNGTQKASSVFWAYNYCPTPYSWVVLLGLILYLAFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGVNWICNVLVSLTFLHVAQYLTYYGAFFLYAALALLGFVFVSGCLPETKGLRLEEIESLFSRRLCSCGAHTDQYMRRLEFGALHYATSEPEGRISYISLQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015144 (carbohydrate transmembrane transporter activity), GO:0051119 (sugar transmembrane transporter activity), GO:0015145 (monosaccharide transmembrane transporter activity), GO:0015149 (hexose transmembrane transporter activity), GO:0005355 (glucose transmembrane transporter activity), GO:0055056 (D-glucose transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0015850 (organic hydroxy compound transport), GO:0015798 (myo-inositol transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098791 (Golgi apparatus subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0005802 (trans-Golgi network)
Protein: Ubiquitin carboxyl-terminal hydrolase (A0A8M2B8Z0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR018200: Ubiquitin specific protease, conserved site (conserved_site) [63-359]
- IPR001394: Peptidase C19, ubiquitin carboxyl-terminal hydrolase (domain) [62-395]
- IPR028889: Ubiquitin specific protease UPS, catalytic domain (domain) [62-398]
- IPR038765: Papain-like cysteine peptidase superfamily (homologous_superfamily) [59-396]
- IPR050185: Ubiquitin carboxyl-terminal hydrolase (family) [56-396]
Sequence:
MPRAESTSMDNSCQALYRTLVTQNGLQPENVDISQSVLYTSIMGLLLVTDKERELQLGNGQVGLRNVGNTCFLNAIVQCLSHTRSLRDYCLMRAYVQDKHSNQEPVLMDEFSKVLAGLWECDAGETTVNPGKFYRVFKESVPYFSGYSQQDAQEFLRFLLDRLHTEINRRPSKRPAVIERKEPAYTRFRISEEAFAMWQRHLDRDDSKIVDLFSGQLRSSLHCSVCSHYSNTFDVFCDLSLPIPKQKSDYGRAVTLRECLDLFSQEEKLDKENSPMCERCNRRTESTKRLTIQRFPRVLVIHLNRFAMSRFSISKSTVPVSFPLTALDLGLFGPVDCGPVLYDLYAVCNHSGTVNMGHYTAACREEEGWCFYNDSCVDAISEEKLQSNQAYVLFYELKSCNISRK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0008233 (peptidase activity), GO:0008234 (cysteine-type peptidase activity), GO:0019783 (ubiquitin-like protein peptidase activity), GO:0101005 (deubiquitinase activity), GO:0004843 (cysteine-type deubiquitinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0021551 (central nervous system morphogenesis), GO:1904888 (cranial skeletal system development), GO:0048731 (system development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0140513 (nuclear protein-containing complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Gamma-aminobutyric acid type B receptor subunit 1 isoform X1 (A0A8M2BHH0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
- IPR002455: GPCR family 3, GABA-B receptor (family) [152-932]
- IPR017978: GPCR family 3, C-terminal (domain) [585-874]
- IPR000436: Sushi/SCR/CCP domain (domain) [27-156]
- IPR028082: Periplasmic binding protein-like I (homologous_superfamily) [165-573]
- IPR002456: GPCR family 3, gamma-aminobutyric acid receptor, type B1 (family) [587-860]
- IPR035976: Sushi/SCR/CCP superfamily (homologous_superfamily) [52-155]
- IPR001828: Receptor, ligand binding region (domain) [184-541]
Sequence:
MALSLVLLFLLGSFSLAMASRNITAGCAIIRPPRDGGIRYRGLTQEQIRSVQVLPVDYEIEYICRGSRVIVGPKVRKCLPDGTWTDLNQRSKCLLPCPRVWTSLENGRVTVHPPGPAVEGTILHYSCLEGFILVGRNSTQCNKLGKWDSPKPVCHYDRHYTGKKKLYIGALFPMSGGWPGGQACLPAAQMALDLVNKRTDILPDYELELIHYDSMCDPGEATKLLYDLLYTEPIKIVLMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVQLFQKWKWTKIATIQQTTEVFTSTLDDLEQRVKEAGIEISVRQSFLTDPAVAVKNLKRQDARIIVGLFYETEARKVFCEVYKEKLYGKKYVWFLIGWYADNWFKIKDPSINCTVEQMTEAVEGHVTTEIVMLNPETVRGASNLTSQEFLAQLMSKLGGKNPEETGGFQEAPLAYDAVWALALALNKTVGPLKAKGRRLEDFNYNNKDITAEIYRALNTSSFEGVSGHVVFDAQGSRMAWTLIEQLQGGSYKKIGYYDMTKGNLSWYGNDRWIGSGPPADQTVVIQKFRYLSQKLFVSVSVFAGLGILMGIVCLTFNIYNSNVRYIQNSQPYLNNMTAVGCMMALAAVFPLGIDGLHVRNSQFPVVCQFRLWLLGLGFSLAYGSMFTKIWWVHTVFTKKDEKKDKRKQHLEPWKLYATVGVLLVIDILSLMIWQIVDPLHITVEKFTKEAPKGDVDELIEPLLQHCSSEKMNTWLGVVYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVSVLCMITAPVTMILSSKQDASFAFASLAIIFSVYITLVVLFVPKMRRLITRGEWQSDQQETMKTGSSTNNNDEEKSRQLERENKELQKIIQEKEERVSELRNQLSERQALRSRKRPTSNQNHSSPSIPTPQNDPKSLLPPPGYPLPSSDNHSFSNSSPLYQPDGKINRNNCHPGRLQLLYKCQH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0004930 (G protein-coupled receptor activity), GO:0016917 (GABA receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0007610 (behavior), GO:0042221 (response to chemical), GO:0030534 (adult behavior), GO:0035094 (response to nicotine), GO:0035095 (behavioral response to nicotine)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0043235 (receptor complex), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:0098802 (plasma membrane signaling receptor complex), GO:0098797 (plasma membrane protein complex), GO:1902710 (GABA receptor complex), GO:0005886 (plasma membrane), GO:0097648 (G protein-coupled receptor complex)
Protein: Paired box protein Pax-3 isoform X1 (A0A8M6Z068)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
- IPR022106: Paired box protein 7, C-terminal (domain) [351-394]
- IPR043565: PAX family (family) [30-461]
- IPR017970: Homeobox, conserved site (conserved_site) [253-276]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [36-286]
- IPR001523: Paired domain (domain) [34-161]
- IPR001356: Homeodomain (domain) [218-282]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [34-165]
- IPR043182: Paired DNA-binding domain (domain) [68-84]
Sequence:
MTALAGGISRMMRPTPPQNYPRGGYSLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQSTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDGICDRNNVPSVSSISRMLRCKFGGNGDEDEDDDEVEKREIEENERRAKHSIDGILGDRSSHSDEGSDVDSEPGLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPSAMSSLQPYQLADSPYPPSSISQVSEQPSTVHRPQPLPPTSVHQSGLGSGPGAQEGSSAYCLSSGRHGFSGYSDGYVAAPGHANPVNPSISNGLPSQVMGLLNPGAVPHQPQSDFALSPLTGGLEPSTGMPASCHSSQRLEALPGLPSMPALPSSQSYCPSSYSSPGYSVDHVASYQYSQYGQSKVPFII
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0043473 (pigmentation), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048870 (cell motility), GO:0048066 (developmental pigmentation), GO:0050931 (pigment cell differentiation), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0016477 (cell migration), GO:0048863 (stem cell differentiation), GO:0048864 (stem cell development), GO:0060485 (mesenchyme development), GO:0048483 (autonomic nervous system development), GO:0007399 (nervous system development), GO:0048762 (mesenchymal cell differentiation), GO:0001667 (ameboidal-type cell migration), GO:0048484 (enteric nervous system development), GO:0014033 (neural crest cell differentiation), GO:0014032 (neural crest cell development), GO:0090497 (mesenchymal cell migration), GO:0001755 (neural crest cell migration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: mitogen-activated protein kinase kinase (A0A8M9QIV0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [308-320]
- IPR017441: Protein kinase, ATP binding site (binding_site) [191-214]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [183-460]
- IPR000719: Protein kinase domain (domain) [185-458]
Sequence:
MRMCPALRMRTAAYREFWRTWQPPRLLQKLLSASEASITAGGWGAHRCSGRSSRVACASETVAENRAREGGLRRSTMAAPSSDSGSSCGGGGTAGPAGLSPRLGSIGAQDSNSCWRCQNETVKRKALKLNFANPPVKPAARLPITSTAPAFQNPHIERLRTHSIESSGKLKISPEQHCDFTAEDLKDLGEIGRGAYGSVNNMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMATSLDKFYKYVYCASDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRNGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPRWNSVFDQLTQVVKGEPPQLCSSEDRQFSHKFIQFVNLCLTKDESKRPKYRELLVRHTASVCKHPFILMYEERLVDVARYVCRILDQMPASPGSPMYVD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004712 (protein serine/threonine/tyrosine kinase activity), GO:0016301 (kinase activity), GO:0004708 (MAP kinase kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009888 (tissue development), GO:0009790 (embryo development), GO:0048598 (embryonic morphogenesis), GO:0048729 (tissue morphogenesis), GO:0060429 (epithelium development), GO:0007369 (gastrulation), GO:0060027 (convergent extension involved in gastrulation), GO:0002009 (morphogenesis of an epithelium), GO:0060026 (convergent extension)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: dynamin GTPase (A0A8M9PHU4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR022812: Dynamin (family) [7-732]
- IPR000375: Dynamin stalk domain (domain) [215-501]
- IPR001849: Pleckstrin homology domain (domain) [514-621]
- IPR030381: Dynamin-type guanine nucleotide-binding (G) domain (domain) [28-294]
- IPR001401: Dynamin, GTPase domain (domain) [6-294]
- IPR045063: Dynamin, N-terminal (domain) [34-207]
- IPR003130: Dynamin GTPase effector (domain) [642-733]
- IPR019762: Dynamin, GTPase region, conserved site (conserved_site) [57-66]
- IPR020850: GTPase effector domain (domain) [647-738]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [3-304]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [514-641]
Sequence:
MGNRGMEELIPLINKLQDAFSSIGQSCNLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLVNNKAEYAEFLHCKGRKFVDFDEVRQEIEAETDRITGSNKGISPIPINLRVYSPNVLNLTLIDLPGMTKVAVGDQPPDIEHQIRDMIMQFITRESCLILAVTPANMDLANSDALKVAKEVDPQGLRTIGVITKLDLMDEGTDARDILENKLLPLRRGYIGVVNRSQKDIDGRKDIRAALAAERKFFLSHPSYRHMAERMGTPHLQKALNQQLTNHIRDTLPGLRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKCIEGSGDQVDTAELSGGARINRIFHERFPFELVKIVFDEKELRREISHAIKNVHGVRTGLFTPDLAFETIVKKQIHKLKEPSLKCVDLVVSELTTVVRKSSKKLSSYPRLREETERIVTTYVREREGKTKDQVLLLIDTELSYINTNHEDFIGFANAQQRNIVNKKRAIPNQVIRKGWLTLNISIMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKLRDVEKGFMSTKHIFAIFNTEQRNVYKDLRQIELACDSQEDMDSWKASFLRAGVYPEKDQVESEEAAPADSFSMDPQLERQVETIRNLVDSYIGIVNKTIRDLMPKTIMHLMINSAKDFIHSELLAYLYSSGDQNSLMEESADQAQRRDEMLRMYHAIKEALSIIGDISTSTISTPVPPPVNDSWIPETSPTPQRRPPTSAPPPNRPPAVRGPTPGPPPLNPTPSFAAPPIPSRPGQPMNAFGNSSQDPFSAPPQIPSRPARIPPGVPSRRPPGAPNRPTIIRPAEPSLLD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009790 (embryo development), GO:0061061 (muscle structure development), GO:0048729 (tissue morphogenesis), GO:0009888 (tissue development), GO:0002009 (morphogenesis of an epithelium), GO:0061053 (somite development), GO:0060429 (epithelium development), GO:0009792 (embryo development ending in birth or egg hatching), GO:0060026 (convergent extension), GO:0043009 (chordate embryonic development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0012505 (endomembrane system), GO:0005905 (clathrin-coated pit), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane)