Protein: protein-tyrosine-phosphatase (A6ISQ6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Single- pass type I membrane protein
InterPro domains:
- IPR029021: Protein-tyrosine phosphatase-like (homologous_superfamily) [686-1196]
- IPR003961: Fibronectin type III (domain) [213-416]
- IPR000998: MAM domain (domain) [1-116]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [115-417]
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [212-410]
- IPR000242: Tyrosine-specific protein phosphatase, PTPase domain (domain) [708-1196]
- IPR000387: Tyrosine-specific protein phosphatases domain (domain) [879-950]
- IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [2-114]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [117-210]
- IPR016130: Protein-tyrosine phosphatase, active site (active_site) [898-908]
- IPR003595: Protein-tyrosine phosphatase, catalytic (domain) [857-958]
- IPR051622: Receptor-type Tyrosine-protein Phosphatases (family) [310-630]
- IPR057598: Receptor-type tyrosine-protein phosphatase U-like, Fn3 domain (domain) [411-555]
- IPR003599: Immunoglobulin domain subtype (domain) [123-211]
Sequence:
MVNASQHAPGQRAHIIFQTLSENDTHCVQFSYFLFSRDGHSPGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALISPDHKGYIGLDDILLFSHPCAKAPHFSRLGDVEVNAGQNASFQCMAAGRAAEAERFFLQRQSGVLVPAAGVRHISHRRFLATFPLASVGRSEQDLYRCVSQAPRGAGVSNFAELIVKEPPTPIAPPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEVHAVNLQTYKLWHLDPDTEYEISVLLTRPGDGGTGRPGPPLLSRTKCAVPGGIAAESLTFTPLEDMIFLKWEEPQEPNGLITQYEISYQSIESSDPAVNVPGPRRTISKLRNETYHVFSNLQPGTTYLFSVRARTSKGFGQAALTEITTNISAPSFDYADMPSPLGESENTITVLLRPAQGRGAPISVYQVVVEEERPRRLRREPGGQDCFSVPLTFETALARGLVHYFGAELAASSLLEAMPFTVGDNQTYRGFWNPPLEPRKAYLIYFQAASHLKGETRLNCIRIARKAACKESKRPLEVSQRSEEMGLILGICAGGLAVLILLLGAIIIIIRKGKPVNMAKATVNYRQEKTHMMTAVDRSFTDQSTLQEDERLGLSFMDAPGYSPRGDQRSSGVTEASSLLGGSPRRPCGRKGSPYHTGQLHPAVRVADLLQHINQMKTAEGYGFKQEYESFFEGWDATKKKDKLKSGRQEPVSAYDRHRVKLHPMLGDPDADYISANYIDGYHRSNHFIATQGPKPEMIYDFWRMVWQEQCVSVVMISKLVEVGRVKCSRYWPEDSDMYGDIKITLVKTETLAEYVVRTFALERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPVVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACLCGETTIPVNEFKATYREMIRIDPQSNSSQLREEFQTLNSVTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISSDGDPNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQYGLMEVEFVSGTANEDLVSRVFRVQNSSRLQEGHLLVRHFQFLRWSAYRDTPDSRKAFLHLLAEVDKWQAESGDGRTVVHCL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0004721 (phosphoprotein phosphatase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0004725 (protein tyrosine phosphatase activity), GO:0016791 (phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0048856 (anatomical structure development), GO:0009719 (response to endogenous stimulus), GO:0042221 (response to chemical), GO:0031099 (regeneration), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0048513 (animal organ development), GO:0048545 (response to steroid hormone), GO:0031100 (animal organ regeneration), GO:0033993 (response to lipid), GO:0014070 (response to organic cyclic compound), GO:0031960 (response to corticosteroid), GO:0051384 (response to glucocorticoid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0098794 (postsynapse), GO:0071944 (cell periphery), GO:0045211 (postsynaptic membrane), GO:0098590 (plasma membrane region), GO:0045202 (synapse), GO:0005886 (plasma membrane), GO:0099572 (postsynaptic specialization), GO:0097060 (synaptic membrane), GO:0099634 (postsynaptic specialization membrane), GO:0098984 (neuron to neuron synapse), GO:0014069 (postsynaptic density), GO:0098978 (glutamatergic synapse), GO:0032279 (asymmetric synapse), GO:0098839 (postsynaptic density membrane)