lokahq/bioreason-rl huggingface dataset:
Protein: Microsomal glutathione S-transferase 2 (Predicted), isoform CRA_a (A6JV75)
Organism: Rattus norvegicus (Rat)
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein
InterPro domains:
- IPR050997: Membrane-associated proteins in eicosanoid and glutathione metabolism (family) [5-136]
- IPR023352: Membrane associated eicosanoid/glutathione metabolism-like domain superfamily (homologous_superfamily) [1-145]
- IPR001129: Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein (family) [9-123]
- IPR001446: 5-lipoxygenase-activating protein (family) [2-102]
Sequence:
MAGDSSLLAAVSLLSACQQSYFALQVGRVRLKYKIAPPAVTGSLEFERIFRAQQNSLEFYSVFIISLWMAGWYFNQVFATCLGLLYIYARHKYFWGYAEAAEKRIIGFRLSLGILALLTVLAVLGVASRFLDEYLDFHVAKKLKRPF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016209 (antioxidant activity), GO:0004601 (peroxidase activity), GO:0016740 (transferase activity), GO:0016829 (lyase activity), GO:0016491 (oxidoreductase activity), GO:0016846 (carbon-sulfur lyase activity), GO:0016684 (oxidoreductase activity, acting on peroxide as acceptor), GO:0004602 (glutathione peroxidase activity), GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups), GO:0004364 (glutathione transferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:1901700 (response to oxygen-containing compound), GO:0043207 (response to external biotic stimulus), GO:1901698 (response to nitrogen compound), GO:0010033 (response to organic substance), GO:0009617 (response to bacterium), GO:0002237 (response to molecule of bacterial origin), GO:0032496 (response to lipopolysaccharide), GO:0010243 (response to organonitrogen compound), GO:0033993 (response to lipid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Similar to homolog of Human holocarboxylase synthetase gene HLCS (Predicted) (A6KPY1)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR045864: Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (homologous_superfamily) [588-811]
- IPR004408: Biotin--acetyl-CoA-carboxylase ligase (family) [611-844]
- IPR004143: Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain (domain) [598-796]
- IPR003142: Biotin protein ligase, C-terminal (domain) [813-860]
Sequence:
MLITLCYLYLWARWGRRPAALVLSTVRRLRASRCSFTFCRAAAQPGGARVCLSRGGRVFCVGESQSVDDLNKWALFLVSPFILEAEHIAFVTESIWVQGTSFQEPSSSETVVKWSDCCLPLACRPGDPYQLIAKASVDNFSKLGVAFMEDRLQMDNGLIAQKIVSVHLKDPALKELSKASNKQVQAPLPSPEASLEAQPAQGVMEQAGQGDWKAAGEGPSPQRRGCAPVSESAADGDPGQGSTELCQLHLSSCHECLELENSTIESVRCASAENIPDLPHDCSSSVEGTAGELCPERKGKRVNISGKAPNILLYVGSGSEEALGQLQQVRSVLTDCVDTDSYTLYHLLEDSALRDPWPDNCLLLVIASRDPIPKGIHHRFMAYLSQGGKVLGLSSSFTFGDLRVARRDVLRNTAQNLVFSKADGSEVRLSVLSSGYVYEEGPSLGRLQGHLENEDKDKMIVHVPFGTHGGEAILCQVHLELPPSAPLVQTTDDFNVLKSSNTRRLEVLKEILTALGLSCDAPQAPALTPLYLLLAAEEIQGPFMQWLARHVDPEGVIKSSKLSLKFVSSYTSEAEITPSSIPVVTDPEGFSSEHFNLETYRQNLQSTRLGRVILFAEVTSTTMSLLDGLMFEMPQEMGLIAIAVRQTQGKGRGPNAWLSPVGCALSTLLVSIPLRSQLGQRIPFVQHLMSLAVVEAVRSIPEYEDINLRVKWPNDIYYSDLMKIGGVLVNSTLVGETFYILIGCGFNVTNSNPTICINDLIEEHNKQNKAGLKPLQADCLIARAVTVLEKLIDRFQDQGPDGVLPLYYKYWAHSGQQVRLGSSEGPAVSIVGLDDSGFLQVHQEGGGVVSVHPDGNSFDMLRNLIVPKRP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016874 (ligase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0016879 (ligase activity, forming carbon-nitrogen bonds)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:0007584 (response to nutrient), GO:1901698 (response to nitrogen compound), GO:0009991 (response to extracellular stimulus), GO:0010033 (response to organic substance), GO:1901700 (response to oxygen-containing compound), GO:0033273 (response to vitamin), GO:0031667 (response to nutrient levels), GO:0014070 (response to organic cyclic compound), GO:0010243 (response to organonitrogen compound)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000785 (chromatin), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome)
Protein: RCG38206, isoform CRA_b (F7ESC7)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR002013: SAC domain (domain) [93-547]
- IPR043573: Polyphosphoinositide phosphatase Fig4-like (family) [11-800]
Sequence:
MPTAAAPIISSVQKLVLYETRARYFLVGSNHAETKFRVLKIDRTEPKDLVVIDDRHVYTQQEVRELLGRLDLGNRTKLSQKGSSGLFRAVSAFGVVGFVRFLEGYYIVLITKRRKMADIGGHAIYKIEDTSMIYIPNDSVRITHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEMLKSETSKTCQESFDIFEDEGLTTQGGSGVFGISSEPYMKYVWNGELLDIIKNSVHRDWLLYIIHGFCGQSKLLIYGRPVYVTLIARRSSRFAGTRFLKRGANCEGDVANEVETEQILCDASVMSFTAGSYSSYVQVRGSVPLFWSQDISTMMPKPPITLDQADPFAHIAALHFDQMLQRFGSPIIILNLVKEREKRKHERILSEELVAAVTYLNQFLPPEHSIVYIPWDMAKYTKSKLCNVLDRLNVIAESVVKKTGFFVNRPDSYCSVLRPDEKWNELGGRVIPTGRLQTGILRTNCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQDSINLFLGVFHPTEGKPHLWELPTDFYLHHKNTMSLLPPKRSYTHWWTPEVVKHLPLPYDEVICAANLKKLTVKKFHRWEEEIDIHNEFFRPYELSSFDDTFCLAMTSSARDFMPKTIGIDPSPFTVRKPDETGKSVLGNKSNREEAVLQRKTAASAPPPPSEEAVSSSSEDDSGTDREDEGSISQRSTPVKMTDTGDSAKVTESVAQPMKEVYGVSLSRSLSEEDHSIYARFVQLGQSQHRQDWSSPQMCARCSDGVIKLTPISAFSQDNIYEVQPPRVDRKSTEIFQAHIQASQGIMQPLGKEDTAIYREYIRNRYL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0016791 (phosphatase activity), GO:0052866 (phosphatidylinositol phosphate phosphatase activity), GO:0052744 (phosphatidylinositol monophosphate phosphatase activity), GO:0034596 (phosphatidylinositol phosphate 4-phosphatase activity), GO:0034593 (phosphatidylinositol bisphosphate phosphatase activity), GO:0004438 (phosphatidylinositol-3-phosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0051130 (positive regulation of cellular component organization), GO:0031344 (regulation of cell projection organization), GO:0031346 (positive regulation of cell projection organization), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0010976 (positive regulation of neuron projection development), GO:0010975 (regulation of neuron projection development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0005783 (endoplasmic reticulum), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0055037 (recycling endosome), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)
Protein: Syntrophin, basic 1 (Predicted) (A6HRH8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm, cytoskeleton
InterPro domains:
- IPR001849: Pleckstrin homology domain (domain) [20-436]
- IPR015482: Syntrophin (family) [19-538]
- IPR041428: Syntrophin, split Pleckstrin homology (PH) domain (domain) [240-300]
- IPR055108: Syntrophin, C-terminal PH domain (domain) [439-537]
- IPR036034: PDZ superfamily (homologous_superfamily) [104-202]
- IPR001478: PDZ domain (domain) [113-196]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [16-453]
Sequence:
MAVAAAAAAVAAPAGGGGARAQRSGLLEVLVRDRWHKVLVNLSEDALVLSCEEGATAYNGIGTTTNGSFCRGSGTGHPGTGVPQAPDSPAGVRTAFTDLPEQVPESISNQKRGVKVLKQELGGLGISIKGGKENKMPILISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGKEVLLEVKYMREATPYVKKGSPVSEIGWETPPPESPRLGSGSADPLSSQPFSFHRDRKSIPLKMCYVTRSMTLADPENRQLEIHSPDAKHTVVLRSKDSATAQAWFSAIHSNVGDLLVRVVADIREQLGKTGIAGSREIRHLGWLAEKVPGESEKQWKPALVVLTEKDLLIYDSMPRRKEAWLSPVHSYPLLATRLVHSGPGKGSPQAAMDLSFATRTGTKQGIETHLFRAEISRDLSHWTRSIVQGCHNSAELTAEITTACTYRNQECRLTIHYDNGFSISTEPQDGAFPKTIIQSPYEKLKMSSDDGIRMLYLDFGGKEGEIQLDLHSCPKPIVFIIHSFLSAKITRLGLVA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019904 (protein domain specific binding), GO:0030165 (PDZ domain binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0003008 (system process), GO:0003012 (muscle system process), GO:0006936 (muscle contraction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0005886 (plasma membrane), GO:0045202 (synapse), GO:0042383 (sarcolemma), GO:0031594 (neuromuscular junction)
Protein: Ephrin A3, isoform CRA_b (A6J6E8)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR001799: Ephrin receptor-binding domain (domain) [1-80]
- IPR008972: Cupredoxin (homologous_superfamily) [1-89]
- IPR031328: Ephrin (family) [1-93]
- IPR019765: Ephrin, conserved site (conserved_site) [32-59]
Sequence:
MVNLSGYRTCNASQGSKRWECNRQHASHSPIKFSEKFQRYSAFSLGYEFHAGQEYYYISTPTHNLHWKCLRMKVFVCCASKDFEGENPQVPKLEKSISGTSPKREHLPLAVGIAFFLMTLLAS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0046875 (ephrin receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0050793 (regulation of developmental process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0045595 (regulation of cell differentiation), GO:0007166 (cell surface receptor signaling pathway), GO:0045664 (regulation of neuron differentiation), GO:0007167 (enzyme-linked receptor protein signaling pathway), GO:0007169 (transmembrane receptor protein tyrosine kinase signaling pathway), GO:0048013 (ephrin receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Synaptogyrin 3 (Predicted), isoform CRA_a (A6HCV1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
- IPR008253: Marvel domain (domain) [20-172]
- IPR016579: Synaptogyrin (family) [1-187]
Sequence:
MEGASFGAGRAGAAFDPVSFAQRPQTLLRVVSWVFSIAVFGPIVNEGYVNSDSGPELRCVFNGNAGACRFGVVLGLGAFIACVAFLLLDVRFQQISSVRDRRRAVLLDLGFSGVWSFLWFVGFCFLTNQWQRTAPGPGTAQAGDAARAAIAFSFFSILSWVALTVKALQRFRLGTDMSLFATDQLGLGTCPSVRHSLGN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019904 (protein domain specific binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0065008 (regulation of biological quality), GO:0032879 (regulation of localization), GO:0001505 (regulation of neurotransmitter levels), GO:0051049 (regulation of transport), GO:0051588 (regulation of neurotransmitter transport), GO:0051580 (regulation of neurotransmitter uptake)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0098793 (presynapse), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0030054 (cell junction), GO:0031090 (organelle membrane), GO:0008021 (synaptic vesicle), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0043227 (membrane-bounded organelle), GO:0030133 (transport vesicle), GO:0070382 (exocytic vesicle), GO:0030672 (synaptic vesicle membrane), GO:0030658 (transport vesicle membrane), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0031982 (vesicle), GO:0012506 (vesicle membrane), GO:0030659 (cytoplasmic vesicle membrane), GO:0099501 (exocytic vesicle membrane), GO:0097708 (intracellular vesicle)
Protein: RCG21182, isoform CRA_c (A6J122)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR032422: Huntingtin-interacting protein 1, clathrin-binding domain (domain) [192-290]
- IPR030224: Sla2 family (family) [2-751]
- IPR035964: I/LWEQ domain superfamily (homologous_superfamily) [505-696]
- IPR002558: I/LWEQ domain (domain) [502-743]
Sequence:
MLYFKRLIQIPRLPEGPPNFLRASALAEHIKPVVVIPEEAPEEEEPENLIEISSGPPAGEPVVVADLFDQTFGPPNGSMKDDRDLQIENLKREVETLRAELEKIKMEAQRYISQLKGQVNSLEAELEEQRKQKQKALVDNEQLRHELAQLKALQLEGARNQGLREEAERKASATEARYSKLKEKHNELINTHAELLRKNADTAKQLTVTQQSQEEVARVKEQLAFQMEQVKRESEMKMEEQSDQLEKLKRELVAKAGELAHAQEALSRTEQSGSELSSRLDTLNAEKEALSGAIRQREAELLAAQSLVREKEEALSQEQQRSAQEKGELQGRLAEKESQEQGLQQKLLDEQFAVLRGAAAEAEAILQDAVSKLDDPLHLRCTSSPDYLVSRAQAALDSVSGLEKGHTQYLASSEDASALVAALTRFSHLAADTIVNGGATSHLAPTDPADRLIDTCRECGARALELMGQLQDQTKLPRAQPSLMRAPLQGILQLGQDLKPKSLDVRQEELGAMVDKEMAATSAAIEDAVRRIEDMMNQARHESSGVKLEVNERILNSCTDLMKAIRLLVMTSTSLQKEIVESGRGAATQQEFYAKNSRWTEGLISASKAVGWGATQLVESADKVVLHMGKYEELIVCSHEIAASTAQLVAASKVKANKNSPHLSRLQECSRTVNERAANVVASTKSGQEQIEDRDTMDFSGLSLIKLKKQEMETQVRVLELEKTLEAERVRLGELRKQHYVLAGGMGTPGEEEPSRPSPAPRSGATKKPPLAQKPSIAPRPDNQLDKKDGVYPAQLVNY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0051015 (actin filament binding), GO:0008092 (cytoskeletal protein binding), GO:0003779 (actin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0034330 (cell junction organization), GO:0099173 (postsynapse organization), GO:0050808 (synapse organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098794 (postsynapse), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0045202 (synapse), GO:0098978 (glutamatergic synapse)
Protein: RCG54594, isoform CRA_c (A6JAY1)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR009079: Four-helical cytokine-like, core (homologous_superfamily) [28-163]
- IPR004213: Flt3 ligand (family) [1-219]
Sequence:
MTVLAPAWSPNSSLLLLLLLLSPCLRGTPDCYFSHSPISSNFHMRISELTDYLLKSYPVTVAINLQDEKHCKALWSLFLAHRWIEQLKTVAGSKMQKLLEDVNTEIHFVTSCTFQPLPECLRFVQTNISHLLQDTCSQLLALKPCIGKACQNFSRCLEVQCQPDSSTLLPPESPGALGATELPKPQPRQLWLLLLLPLTVVLLAAAWCLRWQRTRRRVELRPGGWEPKQGTS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0005102 (signaling receptor binding), GO:0019900 (kinase binding), GO:0030971 (receptor tyrosine kinase binding), GO:0019901 (protein kinase binding), GO:1990782 (protein tyrosine kinase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0002682 (regulation of immune system process), GO:0051239 (regulation of multicellular organismal process), GO:0051240 (positive regulation of multicellular organismal process), GO:0002684 (positive regulation of immune system process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0002694 (regulation of leukocyte activation), GO:0002696 (positive regulation of leukocyte activation), GO:0042127 (regulation of cell population proliferation), GO:0050865 (regulation of cell activation), GO:0050867 (positive regulation of cell activation), GO:0008284 (positive regulation of cell population proliferation), GO:0051251 (positive regulation of lymphocyte activation), GO:0070665 (positive regulation of leukocyte proliferation), GO:0070663 (regulation of leukocyte proliferation), GO:0051249 (regulation of lymphocyte activation), GO:0032816 (positive regulation of natural killer cell activation), GO:0032946 (positive regulation of mononuclear cell proliferation), GO:0050670 (regulation of lymphocyte proliferation), GO:0032814 (regulation of natural killer cell activation), GO:0032944 (regulation of mononuclear cell proliferation), GO:0050671 (positive regulation of lymphocyte proliferation), GO:0032817 (regulation of natural killer cell proliferation), GO:0032819 (positive regulation of natural killer cell proliferation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Tripartite motif protein 25 (Mapped), isoform CRA_b (A6HHZ9)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR051051: E3 ubiquitin-protein ligase TRIM/RNF (family) [7-334]
- IPR058030: TRIM8/14/16/25/29/45/65, coiled-coil region (domain) [215-351]
- IPR017907: Zinc finger, RING-type, conserved site (conserved_site) [28-37]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [5-72]
- IPR027370: Zinc finger, RING-type, eukaryotic (domain) [13-51]
- IPR001841: Zinc finger, RING-type (domain) [13-54]
Sequence:
MAELFPLAEELSCSICLEPFKEPVTTPCGHNFCRSCLNETWVVQGPPYRCPQCRTVYQVRPQLHKNTVLCAVVEQFLQAEQARTPVDDWIPPTRSAASSSDTQVSCDHCLKEVAVKTCLVCMASFCQEHLRPHIDSPAFQDHPLQPPVRDLLRRKCSRHNRLREMFCPEHGECICHICLVEHKTCSPTILSQASADLENKLRQKLTIMYSHINGASKALEDVKSKQQNVQESMKRKMLQLRQEYLEMKAVIDAAETSSTHKLKEEEKRVYGKLDTIYQVLLKKKNEMQNLKAEVELILAKGDEFEFLEKAAKLQEVSTKPVYIPKIDLDHDLIKGVYQGALDLKSELKLSLKQLQEKKAEEPCNSGNVGDHAQSTSKPTRPAKKTAPTLKPNAPQPNSAAVKAKVLENFLTMSRTELLEWWSCRRTTSVV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0009991 (response to extracellular stimulus), GO:1901700 (response to oxygen-containing compound), GO:0007584 (response to nutrient), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0014070 (response to organic cyclic compound), GO:0043627 (response to estrogen), GO:0033273 (response to vitamin), GO:0033993 (response to lipid), GO:0031667 (response to nutrient levels), GO:0033280 (response to vitamin D)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: RCG61291 (A6KDZ6)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR003593: AAA+ ATPase domain (domain) [180-319]
- IPR041569: AAA ATPase, AAA+ lid domain (domain) [340-383]
- IPR003959: ATPase, AAA-type, core (domain) [184-316]
- IPR012340: Nucleic acid-binding, OB-fold (homologous_superfamily) [32-136]
- IPR032501: Proteasomal ATPase, second OB domain (domain) [71-126]
- IPR050221: 26S Proteasome Regulatory ATPase (family) [33-394]
- IPR003960: ATPase, AAA-type, conserved site (conserved_site) [287-305]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [137-393]
Sequence:
MALPGIPYERRLLIMADPRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0016887 (ATP hydrolysis activity), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0008134 (transcription factor binding), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0140296 (general transcription initiation factor binding), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016462 (pyrophosphatase activity), GO:0017025 (TBP-class protein binding), GO:0017111 (ribonucleoside triphosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0044089 (positive regulation of cellular component biogenesis), GO:0051130 (positive regulation of cellular component organization), GO:0044087 (regulation of cellular component biogenesis), GO:0090083 (regulation of inclusion body assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0005829 (cytosol), GO:1902494 (catalytic complex), GO:0005737 (cytoplasm), GO:0140535 (intracellular protein-containing complex), GO:0031597 (cytosolic proteasome complex), GO:0016234 (inclusion body), GO:0000502 (proteasome complex), GO:1905368 (peptidase complex), GO:1905369 (endopeptidase complex)