lokahq/bioreason-rl huggingface dataset:
Protein: Zinc transporter ZIP12 (A6JM58)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
- IPR041137: Zinc transporter ZIP4, N-terminal (domain) [9-88]
- IPR050799: Zinc Iron Protein (ZIP) Transporter (family) [94-554]
- IPR003689: Zinc/iron permease (family) [235-547]
- IPR049406: Zinc transporter ZIP4/12, EF-hand (domain) [96-212]
Sequence:
MSNREYEFYLHSLLSLRQDEDSYFLSEKETDDILASTRKYFGTSTSPCMETKILQRESGIQSSNGADEKMLPQLAATIIALSLQGVCLGRKDSPSPDDFTEYIFSFLNRTNALHLSELEELLNMLSTRRACTKINTLHEHQRKQNTAVHGLRDPKSAAAMDKVSGDHSVSWDQACFSAQQLVEIFLQNHSSLSISKEDFKQLSPGIIQQLLSCSCQVPRDQKAKPPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYSLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAELGHFHESQSPIWKLLGLLGGIHGFFLIEKCFILLVSPNTKGLPLVNGHAGHTHHLGLSPELNDQSGGGKSISTIQLKGPEDSQTAELPKGNVPASNRNRKTISLLAVMVLVGDGLHNFADGLVIGTAFSSSLESGVTTTIAILCHEIPHEMGDFAVLLSSGLSIRTAILMNFLSALTAFIGLYIGLSVSADPRVQDWILTVTAGMFLYLSLVGMLPEMTHVQTQRPWMTFLLQNVGLVLGWFSLLLLAVYEQNIKI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0005385 (zinc ion transmembrane transporter activity), GO:0046873 (metal ion transmembrane transporter activity), GO:0046915 (transition metal ion transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0050793 (regulation of developmental process), GO:0009628 (response to abiotic stimulus), GO:0051239 (regulation of multicellular organismal process), GO:0051094 (positive regulation of developmental process), GO:0051240 (positive regulation of multicellular organismal process), GO:1904018 (positive regulation of vasculature development), GO:2000026 (regulation of multicellular organismal development), GO:0070482 (response to oxygen levels), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0045766 (positive regulation of angiogenesis), GO:0045765 (regulation of angiogenesis), GO:0036293 (response to decreased oxygen levels), GO:1901342 (regulation of vasculature development), GO:1903670 (regulation of sprouting angiogenesis), GO:1903672 (positive regulation of sprouting angiogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Erythrocyte protein band 4.1-like 3, isoform CRA_c (A6KF69)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR018980: FERM, C-terminal PH-like domain (domain) [308-398]
- IPR030691: Band 4.1-like protein 3, FERM domain, F1 sub-domain (domain) [112-195]
- IPR019748: FERM central domain (domain) [195-304]
- IPR008379: Band 4.1, C-terminal (domain) [738-816]
- IPR000798: Ezrin/radixin/moesin-like (family) [126-327]
- IPR007477: SAB domain (domain) [522-569]
- IPR019749: Band 4.1 domain (domain) [109-304]
- IPR000299: FERM domain (domain) [113-394]
- IPR029071: Ubiquitin-like domain superfamily (homologous_superfamily) [113-193]
- IPR014352: FERM/acyl-CoA-binding protein superfamily (homologous_superfamily) [191-298]
- IPR014847: FERM adjacent (domain) [400-446]
- IPR035963: FERM superfamily, second domain (homologous_superfamily) [194-299]
- IPR018979: FERM, N-terminal (domain) [117-179]
- IPR019747: FERM conserved site (conserved_site) [167-303]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [299-393]
Sequence:
MTTESGSDSESKPDQEAEPQEAAGPQEQAGAQAAPEPAGGNVEEQPGLEQFPEAAAHSTPVKREVSDKDRDFAAAAAKQLEYQQFEDDKLSQKSSSSKLSRSPLKIVKRPKSMQCKVTLLDGSEYGCDVDKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQIRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDYDPDECGNDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRASALIDRPAPYFERSSSKRYTMSRSLDGEVGTGQYATTKVISQTNLITTVTPEKKAEEEHVEEEDRRKKAEEATPVAALRHEGKTDSERTDTAADGETSATEELDKTQDELVKHQTNISELKRTFLETSTETALTNEWEKRLSTSPVRLAARQEDAPMIEPLVPEEKLETKTETIETEVEPTPHPQPLSTEKVLQETVLVEERHVMNVHASGDASHTARDDVDATESAPADRHSGNGKEGSSVTEAAKEQRGEEADKSAPEQEQPATVSQEEDQVSAIHSSEGLEQKSHFESSTVKVESISVGSVSPGGVKLETSTKEVPVVHTETKTITYESSQVDPGADLEPGVLMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0005488 (binding), GO:0060090 (molecular adaptor activity), GO:0030674 (protein-macromolecule adaptor activity), GO:0005200 (structural constituent of cytoskeleton), GO:0005515 (protein binding), GO:0008093 (cytoskeletal anchor activity), GO:0043495 (protein-membrane adaptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0043933 (protein-containing complex organization), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0033270 (paranode region of axon), GO:0044304 (main axon), GO:0042995 (cell projection), GO:0120025 (plasma membrane bounded cell projection), GO:0043005 (neuron projection), GO:0030424 (axon)
Protein: Protein tyrosine phosphatase, receptor-type, F interacting protein, binding protein 2, isoform CRA_a (A6I7S4)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR058914: Liprin-beta-1/2, coiled-coil domain (domain) [1-55]
- IPR037619: Liprin-beta-1/2, SAM domain 3 (domain) [520-591]
- IPR029515: Liprin (family) [436-655]
- IPR001660: Sterile alpha motif domain (domain) [433-593]
- IPR037618: Liprin-beta-1/2, SAM domain 2 (domain) [436-497]
- IPR013761: Sterile alpha motif/pointed domain superfamily (homologous_superfamily) [374-611]
Sequence:
MLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQKEQEEKQRKAEELLQELKHLKIKVEELENERNQYEWELKATKAEVAQLQEQVALKDAEIERLHSQLSRSSALHSDHAERDQEIHRLKMGMETLRVANEDKDRRIEELTGLLNQYLRVKEIVMATQGSSERTLSINEDEIEGSFRKWNTTSKSPEEVMKQEVSPRCSSPTPGPPPLPQKSLETRAQKKLSCSLEDLRCESGNKCINGNQTSPVGEPKDSSFLAEQKYPTLPGKLSGATPNGEAAKSPPTASLQPDSSGSSQPKLNRGWSISAPVLGDTEGGWEDIVMTNELSSTSSGTESSPQSPLTPDGKRSPKGIKKFWGKIRRTQSGNFNTDTPGMVEFRRGGLRATAGPRLSRTRDTKGQKCDANAPFAQWSTERVCTWLQDFGLAQYVIFARQWLDHVWVTRWLDDIGLPQYKDQFYESRVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPNCLHRRPADESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNALIGPEAEQEKRDKMASPAYTPLTTTAKVRPRKLGFSHFGNMRKKKFDESTDYICPMEPGDAVSDSHRVYGVYRGLSPLDNHELDGLDQVGQIS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0065008 (regulation of biological quality), GO:0023051 (regulation of signaling), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0001505 (regulation of neurotransmitter levels), GO:0060627 (regulation of vesicle-mediated transport), GO:1903530 (regulation of secretion by cell), GO:0099177 (regulation of trans-synaptic signaling), GO:0051049 (regulation of transport), GO:0010646 (regulation of cell communication), GO:0017157 (regulation of exocytosis), GO:0051588 (regulation of neurotransmitter transport), GO:0051046 (regulation of secretion), GO:0046928 (regulation of neurotransmitter secretion), GO:0050804 (modulation of chemical synaptic transmission), GO:1903305 (regulation of regulated secretory pathway), GO:2000300 (regulation of synaptic vesicle exocytosis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098793 (presynapse), GO:0030054 (cell junction), GO:0045202 (synapse)
Protein: A disintegrin and metallopeptidase domain 6 (A6KC05)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR024079: Metallopeptidase, catalytic domain superfamily (homologous_superfamily) [216-405]
- IPR006586: ADAM, cysteine-rich domain (domain) [502-639]
- IPR000742: EGF-like domain (domain) [664-675]
- IPR001762: Disintegrin domain (domain) [417-503]
- IPR034027: Reprolysin domain, adamalysin-type (domain) [217-405]
- IPR002870: Peptidase M12B, propeptide (domain) [63-124]
- IPR036436: Disintegrin domain superfamily (homologous_superfamily) [416-501]
- IPR001590: Peptidase M12B, ADAM/reprolysin (domain) [229-395]
Sequence:
MLSLTWGMKLVERSVVPRVLLLLFALWLLLLVPVRCSEGHPTWRYISSEVVIPRKEIYHSKGIQTQGRLSYSLRFRGQRHIIHLRRKTLIWPRHLLLTTQDDQGALQMDYPFFPVDCYYFGYLEGIPQSMVTVNTCYGGLEGIMMLDDLAYEIKPLNDSQGFEHIVSQIVSEPDVTGPTNTWKRLNLNTGPPLSRTEYANGTPRMSSKNYASHPAAIKGQFQATNSIYKESNNIDTAARYLFELLSITDSFLITIHMRYYAILLTVFTESDPFALEYTVPGGSIYNYYVSNFFNRLRPDASTVLNKDGPSDNDFHPVEQSLCTPAGLTIVGQHRRSFLALSVMITNRIAMSLGIKADDETYCICHRRTTCIMYKNPEITDAFSNCSLVQINQILNTPGTMSCLFYDHHVYHNITKTYRFCGNFKIDIGEQCDCGSHKACYADPCCGSNCKLTAGSICDKELCCANCTYSPSGTLCRPIQNICDLPEYCSGNNIFCPADTYLQDGTPCSEEGYCYKGNCTDRSVQCKEIFGVNAKGANIKCYDINKQRFRFGHCTRAQESLMFNACSDHDKLCGRLQCTNVTNLPFLQEHVSFHQSVISGFTCFGLDEHRGTETTDAGLVKHGTPCSQTNFCDRGACNGSLSRLDYDCTPEKCNFRGVCNNHRHCHCHLGWKPPLCREEGPSGSTDSGSPPKERRTIKQSREPLLYLRMLFGRLYLFIVSLLFGVATRAGVIKVFKFEDLQAALRAAQAKAT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0003006 (developmental process involved in reproduction), GO:0048608 (reproductive structure development), GO:0045137 (development of primary sexual characteristics), GO:0007548 (sex differentiation), GO:0046661 (male sex differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0008406 (gonad development), GO:0046546 (development of primary male sexual characteristics), GO:0061458 (reproductive system development), GO:0008584 (male gonad development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0044304 (main axon), GO:0042995 (cell projection), GO:0043194 (axon initial segment), GO:0120025 (plasma membrane bounded cell projection), GO:0043005 (neuron projection), GO:0030424 (axon)
Protein: Complement C2 (Q8CIP8)
Organism: Rattus norvegicus (Rat)
Function: Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase
Subcellular location: Secreted
InterPro domains:
- IPR043504: Peptidase S1, PA clan, chymotrypsin-like fold (homologous_superfamily) [468-758]
- IPR009003: Peptidase S1, PA clan (homologous_superfamily) [464-751]
- IPR036465: von Willebrand factor A-like domain superfamily (homologous_superfamily) [194-467]
- IPR011360: Complement B/C2 (family) [20-756]
- IPR001254: Serine proteases, trypsin domain (domain) [470-750]
- IPR033116: Serine proteases, trypsin family, serine active site (active_site) [681-692]
- IPR000436: Sushi/SCR/CCP domain (domain) [22-212]
- IPR002035: von Willebrand factor, type A (domain) [258-463]
- IPR035976: Sushi/SCR/CCP superfamily (homologous_superfamily) [21-212]
- IPR001314: Peptidase S1A, chymotrypsin family (family) [499-692]
- IPR018114: Serine proteases, trypsin family, histidine active site (active_site) [509-514]
Sequence:
MAPLLALFYLLQLGPGLAALSCPQNVNIVGGNFTLSRGWAPGSVLIYSCPLGRYPSPAWRECQSNGQWQTPRASSLPTLRSSRLAKAVCKPVRCPAPTSFENGIYIPRLGSYPVGGNLSFECEHGFTLRGSPVRYCRPNGVWDGETAVCDNGASHCPNPGISVGTMRTGSSFDLGDKVSYRCSSTNLVLTGSVERECLSNGVWSGSEPICRQPYSYDFPEDVASALGTSFTHLLGATNPIQKRTENLGRKIQILRSGHLNLYLLLDASQSVSEKDFNIFKESAFLMVDRIFSFEIKVSVAIITFASRPKIIMSVLNERSQNVMEVMDSLDSVCYKDHENATGTNTYEALNSVYLMMNNQMDRLGMETSAWQEIRHAIILLTDGKSNMGGSPKPAVDNIREILGISRNRNDYLDIYAIGVGKLDVDWKELNELGSKKDGERHAFILQDAKAVQQVFEHILDVSKLTDTICGVGNMSVNASDQERTPWQVTFKPKSKETCQGSLISDQWVLTAAHCFHDAQMEDRHLWRVIVGDPTSHHGKEFHVEEVLVAPGFNVHAKQSQGISEFYADDIALLKLSQRVKMSSHARPICLPCTVGANMALRRSPGSTCKDHETELLSQQKVPAHFVALNGNRMNINLRTGPERTSCIEAVSQNKGSFPGLTNVSEVVTDQFLCSGMEGDDSPCKGESGGAVFLERRYRFFQVGLVSWGLFDPCHGSSNKNLRRKPPHGVVPRDFHISLFRLQPWLRQHLDGVLDFLPL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:0007584 (response to nutrient), GO:0009991 (response to extracellular stimulus), GO:0031667 (response to nutrient levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: RCG40488, isoform CRA_a (A6I8D5)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR057971: Pleckstrin homology domain-containing family A member 4-7, TBCA domain (domain) [16-153]
Sequence:
MTGRDLLKDRSLKPMKIAESDTDVKLSIFCEQDRILQDLEDKIRALKENKDQLESVLEVLHRQTEQYRDQPQHLEKITCQQRLLQEDLVHIRAELCRESTEMENAWNEYLKLEKDVEQLKQTLQEQHRRAFFFQEKSQIQKDLWRIEDVMAGLSVNKENYRVLVGSVKNPERKTVPLFPHPSVPSLSPTESKPALQPSPPTSPVRTPLEVRLFPQLQTYVPYRPHPPQLRKVVSPLQSPTKATPQAEDEAPPRPPLPELYSPEDQPPAVPPLPREATIIRHTSVRGLKRQSDERKRDREQGQCVNGDLKVELRSYVSEPELASFSGDVPRPSLGLVGSESRYQTLPGRGLSGSTSRLQQSSTIAPYVTLRRGLNAENSSVTFSRPKSALERLYSGDHQRGKMSAEEQLERMKRHQKALVRERKRTLSQGERTGLLSARYLSQPLPGDLGSWKREQEFDLQLLERAAQGDRKDKEEGWLKVQATPVMELDLEPQDYDLDINRELSKPEKVSIPERYVEVDPEEPPSVEELQARYQKAEKIRNILARSSMCNLQPPGQDRNSLADLDTQMQEQERIINISYALASEASQRSKQVAAQAVTDP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0032501 (multicellular organismal process), GO:0065008 (regulation of biological quality), GO:0003008 (system process), GO:0003013 (circulatory system process), GO:0090066 (regulation of anatomical structure size), GO:0008015 (blood circulation), GO:0003018 (vascular process in circulatory system), GO:0035150 (regulation of tube size), GO:0097746 (blood vessel diameter maintenance), GO:0035296 (regulation of tube diameter), GO:0042311 (vasodilation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0098794 (postsynapse), GO:0030054 (cell junction), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0099572 (postsynaptic specialization), GO:0043228 (non-membrane-bounded organelle), GO:0098984 (neuron to neuron synapse), GO:0099091 (postsynaptic specialization, intracellular component), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0014069 (postsynaptic density), GO:0098978 (glutamatergic synapse), GO:0032279 (asymmetric synapse), GO:0099092 (postsynaptic density, intracellular component)
Protein: Protein tyrosine phosphatase, receptor-type, F interacting protein, binding protein 2, isoform CRA_c (A6I7S2)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR058914: Liprin-beta-1/2, coiled-coil domain (domain) [28-133]
- IPR037619: Liprin-beta-1/2, SAM domain 3 (domain) [645-716]
- IPR029515: Liprin (family) [16-780]
- IPR001660: Sterile alpha motif domain (domain) [486-718]
- IPR037617: Liprin-beta-1/2, SAM domain 1 (domain) [486-549]
- IPR037618: Liprin-beta-1/2, SAM domain 2 (domain) [560-622]
- IPR013761: Sterile alpha motif/pointed domain superfamily (homologous_superfamily) [452-736]
Sequence:
MLSGAEGIFVASPSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQKEQEEKQRKAEELLQELKHLKIKVEELENERNQYEWELKATKAEVAQLQEQVALKDAEIERLHSQLSRSSALHSDHAERDQEIHRLKMGMETLRVANEDKDRRIEELTGLLNQYLRVKEIVMATQGSSERTLSINEDEIEGSFRKWNTTSKSPEEVMKQEVSPRCSSPTPGPPPLPQKSLETRAQKKLSCSLEDLRCESGNKCINGNQTSPVGEPKDSSFLAEQKYPTLPGKLSGATPNGEAAKSPPTASLQPDSSGSSQPKLNRGWSISAPVLGDTEGGWEDIVMTNELSSTSSGTESSPQSPLTPDGKRSPKGIKKFWGKIRRTQSGNFNTDTPGMVEFRRGGLRATAGPRLSRTRDTKGQKCDANAPFAQWSTERVCTWLQDFGLAQYVIFARQWVASGHTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINTKQEEKSALLDHVWVTRWLDDIGLPQYKDQFYESRVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPNCLHRRPADESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNALIGPEAEQEKRDKMASPAYTPLTTTAKVRPRKLGFSHFGNMRKKKFDESTDYICPMEPGDAVSDSHRVYGVYRGLSPLDNHELDGLDQVGQIS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098793 (presynapse), GO:0030054 (cell junction), GO:0045202 (synapse)
Protein: Colony stimulating factor 3 receptor (Granulocyte) (Predicted), isoform CRA_b (A6IS82)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Single- pass type I membrane protein
InterPro domains:
- IPR003961: Fibronectin type III (domain) [124-622]
- IPR010457: Immunoglobulin C2-set-like, ligand-binding (domain) [25-118]
- IPR052672: Type I Cytokine Receptor Family, Type 2 Subfamily (family) [120-715]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [25-621]
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [121-619]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [26-120]
- IPR003529: Long hematopoietin receptor, Gp130 family 2, conserved site (conserved_site) [415-466]
Sequence:
MVGLGACNLTGVTLIVLLLPRSLEGCGQIRISPPIVHLGDPVLASCTISPNCSKLDRQPKILWRLQDEPNQPGDRQHHLPDGSQESIITLPHLNYTQAFLFCLVPWNNSFQVLDQAELRAGYPPASPSNLSCLMYLTTNSLVCQWEPGPETHLPTSFILKSFRSRTGCQYQGGTILDCMPKKRHSNCSIPRKHLLLYQNMVIWVQAENMLGSSESPKLCIDPMDVVKLEPPMLQALDIGHDIVSRQPGCLWLSWKPWKPSEFMEQECELRYQPQLEGANWTLVSHLPSSTDRFELCSLHQAPVYTLQLRCIRSSLPGLWSSWSPGLQLRPTIKAPTIRLDTWWQKKHLDPETVRMQLFWKPTPLQKDSGQIQGYLLSWSCPDGQGRIMHLCNTTELSCTFHLPSEAQNVTLVAYNSAGTSSPTLVVFLEHEGPAVTSLHAMAQDLGSIWVDWEAPSLLPQGYLIEWGPDSHKYSNNSWRIEPNGNTTGILLEDNIHPFQLYRITVAPLYPGTVGPPVNVYTYSGEKALPHAPELYLKHVGRTWAQLEWVPETPWLGMIPLTNYTIFWTDARDHSFSVTLNISFHDFVLDHLKPASLYHVYLMATSRAGSTNSTGLTLMTMALDSSDVNIFLGILCFVLLSITCATAWFCCKQSRKTFFWPNVPDPAHSSLSAWVPTIMTEETFQLPSFWGSSVPSITKITELEEDKKPTHWDPSESSGTGSLPAVVQAYVLQGDPREISNQFQPPSSTNDQVLYGQVLGSPTSPEVVGYLRCDSTQPLLGGPTPSPKSYENIWFHSRPQETFIPQPPSQEDDCVFGPPFDFPLFQGLQVHGVEEQGGF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0005515 (protein binding), GO:0019955 (cytokine binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0048856 (anatomical structure development), GO:0009653 (anatomical structure morphogenesis), GO:0009887 (animal organ morphogenesis), GO:0048513 (animal organ development), GO:0097186 (amelogenesis), GO:0042476 (odontogenesis), GO:0042475 (odontogenesis of dentin-containing tooth)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)
Protein: Procollagen, type VI, alpha 2, isoform CRA_b (A6JKB9)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR008160: Collagen triple helix repeat (repeat) [263-307]
- IPR002035: von Willebrand factor, type A (domain) [52-242]
- IPR050525: Extracellular Matrix Assembly and Organization (family) [43-263]
- IPR036465: von Willebrand factor A-like domain superfamily (homologous_superfamily) [39-248]
Sequence:
MTTTTKMLQGSFSVLLLGGLLGVLHAQQQEAISPDISTTDRNNNCPEKADCPVNVYFVLDTSESVAMQSPTDSLLYHMQQFVPQFISQLQNEFYLEQVALSWRYGGLHFSDQVEVFSPPGSDRASFTKSLQGIRSFRRGTFTDCALANMTQQIRQHVGRGVVNFAVVITDGHVTGNPCGGIKMQAERAREEGIRLFAVAPNRNLNEQGLRDIANTPHELYRNNYATMRPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIPGPHGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKPLPFHFRFSFMHPLVPSEGLHQLCPGPCLSLPVISYLRRSTLRAPCHMPNGPIKVLSLPAA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005518 (collagen binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:1901700 (response to oxygen-containing compound), GO:0009743 (response to carbohydrate), GO:0034284 (response to monosaccharide), GO:0009746 (response to hexose), GO:0009749 (response to glucose)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)