Protein: Cd86 antigen, isoform CRA_a (A6IRC5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Single- pass type I membrane protein
InterPro domains:
- IPR013162: CD80-like, immunoglobulin C2-set (domain) [133-215]
- IPR013106: Immunoglobulin V-set domain (domain) [29-106]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [21-224]
- IPR051713: T-cell Activation and Immune Regulation Protein (family) [5-288]
- IPR037677: CD86, IgV domain (domain) [20-127]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [22-127]
- IPR007110: Immunoglobulin-like domain (domain) [27-116]
Sequence:
MYLGILFSVLAYLLSDAVPVKRQAYFNSTAYLPCPFTKAQNISPSELVVFWQDRKKSVLYEHYLGAEKLDNVNAKYLGRTSFDRDNQALRLHNVQIKDTGLYDCFIQQKTPTGSIILQQWETELSVIANFSEPEIEEAQNETRNTGINLTCSSKQGYPKPTKMYFLITNSTNEYGDNMQISQDNVTKLFSVSISLSLPFPDGVYNMTIVCILETESMNISSKPHNMVFSQPQFDRKTWIQIAGPSSLLCCLFLLVVYKAVKKCLKMQNQPGRPSRKTCESKQDSGVDESINLEEVEPQLHQQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0002376 (immune system process), GO:0048519 (negative regulation of biological process), GO:0009605 (response to external stimulus), GO:0048856 (anatomical structure development), GO:0042221 (response to chemical), GO:0045321 (leukocyte activation), GO:0008283 (cell population proliferation), GO:0006955 (immune response), GO:0051240 (positive regulation of multicellular organismal process), GO:0002684 (positive regulation of immune system process), GO:0051241 (negative regulation of multicellular organismal process), GO:0051239 (regulation of multicellular organismal process), GO:0050793 (regulation of developmental process), GO:0002683 (negative regulation of immune system process), GO:0009607 (response to biotic stimulus), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0007568 (aging), GO:0051093 (negative regulation of developmental process), GO:0051707 (response to other organism), GO:0048869 (cellular developmental process), GO:0001775 (cell activation), GO:0002682 (regulation of immune system process), GO:0002252 (immune effector process), GO:0006950 (response to stress), GO:0048522 (positive regulation of cellular process), GO:0043207 (response to external biotic stimulus), GO:0048468 (cell development), GO:0002366 (leukocyte activation involved in immune response), GO:0009410 (response to xenobiotic stimulus), GO:0030154 (cell differentiation), GO:0030155 (regulation of cell adhesion), GO:0002694 (regulation of leukocyte activation), GO:0046649 (lymphocyte activation), GO:0010035 (response to inorganic substance), GO:0070661 (leukocyte proliferation), GO:0009615 (response to virus), GO:0050865 (regulation of cell activation), GO:0009620 (response to fungus), GO:0008284 (positive regulation of cell population proliferation), GO:0006952 (defense response), GO:1901700 (response to oxygen-containing compound), GO:0045785 (positive regulation of cell adhesion), GO:0010033 (response to organic substance), GO:0071216 (cellular response to biotic stimulus), GO:0045087 (innate immune response), GO:0050867 (positive regulation of cell activation), GO:0098542 (defense response to other organism), GO:0002643 (regulation of tolerance induction), GO:0002696 (positive regulation of leukocyte activation), GO:0042127 (regulation of cell population proliferation), GO:0070887 (cellular response to chemical stimulus), GO:0009617 (response to bacterium), GO:0002263 (cell activation involved in immune response), GO:0002274 (myeloid leukocyte activation), GO:0022409 (positive regulation of cell-cell adhesion), GO:0022407 (regulation of cell-cell adhesion), GO:0002237 (response to molecule of bacterial origin), GO:0070663 (regulation of leukocyte proliferation), GO:0001773 (myeloid dendritic cell activation), GO:0051251 (positive regulation of lymphocyte activation), GO:0070665 (positive regulation of leukocyte proliferation), GO:1901701 (cellular response to oxygen-containing compound), GO:0051249 (regulation of lymphocyte activation), GO:0001878 (response to yeast), GO:0010038 (response to metal ion), GO:0030097 (hemopoiesis), GO:0034097 (response to cytokine), GO:0046651 (lymphocyte proliferation), GO:0032496 (response to lipopolysaccharide), GO:0071219 (cellular response to molecule of bacterial origin), GO:0002521 (leukocyte differentiation), GO:0051607 (defense response to virus), GO:0071310 (cellular response to organic substance), GO:0030099 (myeloid cell differentiation), GO:0032943 (mononuclear cell proliferation), GO:0140546 (defense response to symbiont), GO:0071241 (cellular response to inorganic substance), GO:0033993 (response to lipid), GO:0042110 (T cell activation), GO:0034341 (response to type II interferon), GO:0002285 (lymphocyte activation involved in immune response), GO:0043011 (myeloid dendritic cell differentiation), GO:0002286 (T cell activation involved in immune response), GO:0071222 (cellular response to lipopolysaccharide), GO:0050670 (regulation of lymphocyte proliferation), GO:0050863 (regulation of T cell activation), GO:0032944 (regulation of mononuclear cell proliferation), GO:0050671 (positive regulation of lymphocyte proliferation), GO:0071345 (cellular response to cytokine stimulus), GO:0042098 (T cell proliferation), GO:0032946 (positive regulation of mononuclear cell proliferation), GO:1903131 (mononuclear cell differentiation), GO:0002573 (myeloid leukocyte differentiation), GO:0050870 (positive regulation of T cell activation), GO:0071396 (cellular response to lipid), GO:0071248 (cellular response to metal ion), GO:1903037 (regulation of leukocyte cell-cell adhesion), GO:1903039 (positive regulation of leukocyte cell-cell adhesion), GO:0042102 (positive regulation of T cell proliferation), GO:0097028 (dendritic cell differentiation), GO:0042129 (regulation of T cell proliferation), GO:0042104 (positive regulation of activated T cell proliferation), GO:0046006 (regulation of activated T cell proliferation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009986 (cell surface)