Protein: MYO9B variant protein (B0I1T6)
Organism: Homo sapiens (Human)
InterPro domains:
- IPR002219: Protein kinase C-like, phorbol ester/diacylglycerol-binding domain (domain) [1632-1681]
- IPR046987: Unconventional class IX myosin (family) [1-2152]
- IPR036023: Class IX myosin, motor domain (domain) [160-941]
- IPR000198: Rho GTPase-activating protein domain (domain) [1703-1888]
- IPR000048: IQ motif, EF-hand binding site (binding_site) [955-1045]
- IPR028557: Unconventional myosin-IXb, Rho-GAP domain (domain) [1698-1883]
- IPR036961: Kinesin motor domain superfamily (homologous_superfamily) [149-888]
- IPR029071: Ubiquitin-like domain superfamily (homologous_superfamily) [18-112]
- IPR008936: Rho GTPase activation protein (homologous_superfamily) [1690-1900]
- IPR001609: Myosin head, motor domain-like (domain) [140-954]
- IPR000159: Ras-associating domain (domain) [15-114]
- IPR046989: Unconventional myosin-IXb, RA domain (domain) [16-112]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [144-1048]
- IPR046349: C1-like domain superfamily (homologous_superfamily) [1624-1684]
Sequence:
MSVKEAGSSGRREQAAYHLHIYPQLSTTESQASCRVTATKDSTTSDVIKDAIASLRLDGTKCYVLVEVKESGGEEWVLDANDSPVHRVLLWPRRAQDEHPQEDGYYFLLQERNADGTIKYVHMQLVAQATATRRLVERGLLPRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMDPVAVFRWAVLRAAIRAMAVLREAGRLRAERAEKAAGMSSPGAQSHPEELPRGASTPSEKLYRDLHNQMIKSIKGLPWQGEDPRSLLQSLSRLQKPRAFILKSKGIKQKQIIPKNLLDSKSLKLIISMTLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVLLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGGQQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPSRRVTQEQGVSLLEDKKESREDETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKTLPSGSPRPGQLERPTSLALDSRVSPPAPGSAPETPEDKSKPCGSPRVQEKPDSPGGSTQIQRYLDAERLASAVELWRGKKLVAAASPSAMLSQSLDLSDRHRATGAALTPTEERRTSFSTSDVSKLLPSLAKAQPAAETTDGERSAKKPAVQKKKPGDASSLPDAGLSPGSQVDSKSTFKRLFLHKTKDKKYSLEGAEELENAVSGHVVLEATTMKKGLEAPSGQQHRHAAGEKRTKEPGGKGKKNRNVKIGKITVSEKWRESVFRQITNANELKYLDEFLLNKINDLRSQKTPIESLFIEATEKFRSNIKTMYSVPNGKIHVGYKDLMENYQIVVSNLATERGQKDTNLVLNLFQSLLDEFTRGYTKNDFEPVKQSKAQKKKRKQERAVQEHNGHVFASYQVSIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSHCSYTYGRKGEPGVEPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKITTCVEMLIKEQMRKYKVKMEEISQLEAAESIAFRRLSLLRQNAPWPLKLGFSSPYEGVLNKSPKTRDIQEEELEVLLEEEAAGGDEDREKEILIERIQSIKEEKEDITYRLPELDPRGSDEENLDSETSASTESLLEERAGRGASEGPPAPALPCPGAPTPSPLPTVAAPPRRRPSSFVTVRVKTPRRTPIMPTANIKLPPGLPSHLPRWAPGAREAAAPVRRREPPARRPDQIHSVYITPGADLPVQGALEPLEEDGQPPGAKRRYSDPPTYCLPPASGQTNG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003774 (cytoskeletal motor activity), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0140657 (ATP-dependent activity), GO:0030234 (enzyme regulator activity), GO:0036094 (small molecule binding), GO:0097159 (organic cyclic compound binding), GO:0140677 (molecular function activator activity), GO:1901363 (heterocyclic compound binding), GO:0000146 (microfilament motor activity), GO:0043167 (ion binding), GO:0097367 (carbohydrate derivative binding), GO:0005515 (protein binding), GO:1901265 (nucleoside phosphate binding), GO:0060589 (nucleoside-triphosphatase regulator activity), GO:0043168 (anion binding), GO:0005516 (calmodulin binding), GO:0008047 (enzyme activator activity), GO:0008092 (cytoskeletal protein binding), GO:0005102 (signaling receptor binding), GO:0000166 (nucleotide binding), GO:0032553 (ribonucleotide binding), GO:0019899 (enzyme binding), GO:0043531 (ADP binding), GO:0005096 (GTPase activator activity), GO:0003779 (actin binding), GO:0017076 (purine nucleotide binding), GO:0035639 (purine ribonucleoside triphosphate binding), GO:0030695 (GTPase regulator activity), GO:0051020 (GTPase binding), GO:0032555 (purine ribonucleotide binding), GO:0005524 (ATP binding), GO:0031267 (small GTPase binding), GO:0032559 (adenyl ribonucleotide binding), GO:0030554 (adenyl nucleotide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0030029 (actin filament-based process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0030048 (actin filament-based movement), GO:0007166 (cell surface receptor signaling pathway), GO:0035556 (intracellular signal transduction), GO:0010646 (regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0007264 (small GTPase mediated signal transduction), GO:1902531 (regulation of intracellular signal transduction), GO:0007265 (Ras protein signal transduction), GO:0051056 (regulation of small GTPase mediated signal transduction), GO:0007266 (Rho protein signal transduction), GO:0046578 (regulation of Ras protein signal transduction), GO:0035023 (regulation of Rho protein signal transduction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)