Protein: Beta-galactosidase (A6I3N5)
Organism: Rattus norvegicus (Rat)
Function: Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans
InterPro domains:
- IPR031330: Glycoside hydrolase 35, catalytic domain (domain) [42-357]
- IPR017853: Glycoside hydrolase superfamily (homologous_superfamily) [33-359]
- IPR001944: Glycoside hydrolase, family 35 (family) [27-644]
- IPR008979: Galactose-binding-like domain superfamily (homologous_superfamily) [478-646]
- IPR048912: Beta-galactosidase 1-like , first all-beta domain (domain) [404-517]
- IPR048913: Beta-galactosidase, galactose-binding domain (domain) [551-612]
- IPR026283: Beta-galactosidase 1-like (family) [8-646]
- IPR019801: Glycoside hydrolase, family 35, conserved site (conserved_site) [178-190]
Sequence:
MFRVPLCMLLPLLALLQLLGAAHSFYNVSQRTFELDYKRDRFLKDGQPFRYISGSIHYFRIPRFYWEDRLLKMKMAGLDAIQTYVPWNFHEPQPGQYDFSGDRDVEHFIQLAHQLGLLVILRPGPYICAEWDMGGLPAWLLEKESIVLRSSDPDYLAAVDKWLAVLLPKMKRLLYQNGGPIITVQVENEYGSYFACDYNYLRFLEHRFRYHLGNDIILFTTDGAAEKLLKCGTLQDLYATVDFGTTGNITRAFLIQRNFEPKGPLINSEFYTGWLDHWGQPHSKVNTKKLVASLYNLLAYGASVNLYMFIGGTNFAYWNGANMPYAPQPTSYDYDAPLSEAGDLTEKYFAVRDVIRKFKEVPEGPIPPSTPKFAYGKVALRKFKTVTEALGILCPNGPVKSLYPLTFTQVKQYFGYVLYRTTLPQDCSNPKPIFSSPINGVRDRAYVSVDGVPQGILDRNRMNVLNIRGKAGATLDILVENMGRVNYGNSIKDFKGLISNMTLNFTVLTNWTMFPLDTEALARSHLGNWEAADEGHLDGHSTLRSSNFTLPTFYVGNFSIPSGIPDLPQDTFIQFPGWAKGQVWINGFNLGRYWPTKGPQMTLFVPRNILTTSAPNNITVLELESSPCSNGTLELCTVEFVDTPVIG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0097367 (carbohydrate derivative binding), GO:0016787 (hydrolase activity), GO:0016936 (galactoside binding), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds), GO:0015925 (galactosidase activity), GO:0004565 (beta-galactosidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0009056 (catabolic process), GO:0009719 (response to endogenous stimulus), GO:0044238 (primary metabolic process), GO:1901700 (response to oxygen-containing compound), GO:0005996 (monosaccharide metabolic process), GO:0005975 (carbohydrate metabolic process), GO:1901575 (organic substance catabolic process), GO:0044282 (small molecule catabolic process), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0048545 (response to steroid hormone), GO:0097305 (response to alcohol), GO:0019318 (hexose metabolic process), GO:0014070 (response to organic cyclic compound), GO:0046365 (monosaccharide catabolic process), GO:1901654 (response to ketone), GO:0016052 (carbohydrate catabolic process), GO:0033993 (response to lipid), GO:0031960 (response to corticosteroid), GO:0006012 (galactose metabolic process), GO:0019320 (hexose catabolic process), GO:0051384 (response to glucocorticoid), GO:0019388 (galactose catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0005773 (vacuole), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0005764 (lysosome)