Protein: histone acetyltransferase (A6KUI5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus
InterPro domains:
- IPR000182: GNAT domain (domain) [402-550]
- IPR001487: Bromodomain (domain) [620-728]
- IPR016181: Acyl-CoA N-acyltransferase (homologous_superfamily) [410-552]
- IPR036427: Bromodomain-like superfamily (homologous_superfamily) [612-730]
- IPR037800: Histone acetyltransferase GCN5 (family) [2-727]
- IPR009464: PCAF, N-terminal (domain) [4-226]
- IPR018359: Bromodomain, conserved site (conserved_site) [644-701]
Sequence:
MAEESCKCNGWKNPNPSPTPPRGDLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEEDADTKQVYFYLFKLLRKSILQRGKPMVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPSKERQTTIELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPRYETTKVFGRTLLRSVFTIMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFLSASSRTSPLGIQTVISPPVTGTALFSSNSTSHEQINGGRTSPGCRSSSGLEANPGEKRKMNNSHAPEEAKRSRVMGDIPVELISEVMSTITDPAGMLGPETNFLSAHSARDEAARLEERRGVIEFHVVGNSLNQKPNKKMLMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHEILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPQIPYTEFSVIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPKDPEQLYSTLKNILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLRNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCASVLEKFFFSKIKEAGLMDK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0042826 (histone deacetylase binding), GO:0035035 (histone acetyltransferase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0003008 (system process), GO:0065008 (regulation of biological quality), GO:0048522 (positive regulation of cellular process), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0051716 (cellular response to stimulus), GO:0065009 (regulation of molecular function), GO:0006950 (response to stress), GO:0044238 (primary metabolic process), GO:0007610 (behavior), GO:0044093 (positive regulation of molecular function), GO:1901564 (organonitrogen compound metabolic process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0006979 (response to oxidative stress), GO:0019538 (protein metabolic process), GO:0071495 (cellular response to endogenous stimulus), GO:0060255 (regulation of macromolecule metabolic process), GO:0051130 (positive regulation of cellular component organization), GO:0051098 (regulation of binding), GO:0043170 (macromolecule metabolic process), GO:0003013 (circulatory system process), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0009891 (positive regulation of biosynthetic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0007611 (learning or memory), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0050877 (nervous system process), GO:0080090 (regulation of primary metabolic process), GO:0051128 (regulation of cellular component organization), GO:0090066 (regulation of anatomical structure size), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0034599 (cellular response to oxidative stress), GO:0003018 (vascular process in circulatory system), GO:0050890 (cognition), GO:0031344 (regulation of cell projection organization), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0008015 (blood circulation), GO:0051246 (regulation of protein metabolic process), GO:0071310 (cellular response to organic substance), GO:0062197 (cellular response to chemical stress), GO:0071107 (response to parathyroid hormone), GO:0010468 (regulation of gene expression), GO:0035150 (regulation of tube size), GO:0051099 (positive regulation of binding), GO:0007613 (memory), GO:0036211 (protein modification process), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0032870 (cellular response to hormone stimulus), GO:0043412 (macromolecule modification), GO:0031346 (positive regulation of cell projection organization), GO:0035561 (regulation of chromatin binding), GO:0031326 (regulation of cellular biosynthetic process), GO:0051247 (positive regulation of protein metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0031399 (regulation of protein modification process), GO:0035563 (positive regulation of chromatin binding), GO:2001141 (regulation of RNA biosynthetic process), GO:0010976 (positive regulation of neuron projection development), GO:0043543 (protein acylation), GO:0006355 (regulation of DNA-templated transcription), GO:0097746 (blood vessel diameter maintenance), GO:0035296 (regulation of tube diameter), GO:1902680 (positive regulation of RNA biosynthetic process), GO:0071374 (cellular response to parathyroid hormone stimulus), GO:0031401 (positive regulation of protein modification process), GO:0006357 (regulation of transcription by RNA polymerase II), GO:0031058 (positive regulation of histone modification), GO:0045893 (positive regulation of DNA-templated transcription), GO:0031056 (regulation of histone modification), GO:0042311 (vasodilation), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:0006473 (protein acetylation), GO:1903506 (regulation of nucleic acid-templated transcription), GO:1901983 (regulation of protein acetylation), GO:1901985 (positive regulation of protein acetylation), GO:0010975 (regulation of neuron projection development), GO:0035066 (positive regulation of histone acetylation), GO:0045944 (positive regulation of transcription by RNA polymerase II), GO:2000758 (positive regulation of peptidyl-lysine acetylation), GO:2000756 (regulation of peptidyl-lysine acetylation), GO:0035065 (regulation of histone acetylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000785 (chromatin), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome), GO:0005634 (nucleus)