Protein: Runt-related transcription factor (A0A8M9PJ75)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
- IPR012346: p53/RUNT-type transcription factor, DNA-binding domain superfamily (homologous_superfamily) [53-192]
- IPR016554: Runt-related transcription factor RUNX (family) [4-395]
- IPR000040: Acute myeloid leukemia 1 protein (AML1)/Runt (family) [8-386]
- IPR027384: Runx, central domain superfamily (homologous_superfamily) [246-285]
- IPR008967: p53-like transcription factor, DNA-binding domain superfamily (homologous_superfamily) [57-182]
- IPR013711: Runx, C-terminal domain (domain) [303-395]
- IPR013524: Runt domain (domain) [55-183]
Sequence:
MVFLWDAKYEPAPGRRFTPPSTTLSSGKMSEGLPLGAQESTGAALVGKLRMADRSMVEVLSDHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDIPDGTLVTVMAGNDENYSAELRNATAAIKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYQRAIKITVDGPREPRHSRQMQTSPSWSYEQSYPYLGPISTPAVHPTTPISPNRTALHCPELTAFTDPRVGLERSFPSLPSLPDGRFSDPRVPYPTGAFTYTPTPVTSAIGIGMSAMSSPAGRYHTYLPPAYPAGSSQAQAGAFQASSSPYHLYYSSAAGSYQFSMMPSGGAAAGERSPPRILPCTNASTGSALLHPSLPNQSEGVVEAEGSHSSSPTSMSVEAVWRPY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:1901363 (heterocyclic compound binding), GO:0097159 (organic cyclic compound binding), GO:0003676 (nucleic acid binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003677 (DNA binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding), GO:0000987 (cis-regulatory region sequence-specific DNA binding), GO:0000977 (RNA polymerase II transcription regulatory region sequence-specific DNA binding), GO:0000978 (RNA polymerase II cis-regulatory region sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0002376 (immune system process), GO:0040007 (growth), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0048589 (developmental growth), GO:0007275 (multicellular organism development), GO:0001775 (cell activation), GO:0009653 (anatomical structure morphogenesis), GO:0045321 (leukocyte activation), GO:0019222 (regulation of metabolic process), GO:0051240 (positive regulation of multicellular organismal process), GO:0002684 (positive regulation of immune system process), GO:0002682 (regulation of immune system process), GO:0051239 (regulation of multicellular organismal process), GO:0050793 (regulation of developmental process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0051094 (positive regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0040008 (regulation of growth), GO:0048522 (positive regulation of cellular process), GO:0045597 (positive regulation of cell differentiation), GO:0048638 (regulation of developmental growth), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0001568 (blood vessel development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0010714 (positive regulation of collagen metabolic process), GO:0034103 (regulation of tissue remodeling), GO:0048513 (animal organ development), GO:0030155 (regulation of cell adhesion), GO:0060255 (regulation of macromolecule metabolic process), GO:0046620 (regulation of organ growth), GO:0051130 (positive regulation of cellular component organization), GO:1903706 (regulation of hemopoiesis), GO:0010712 (regulation of collagen metabolic process), GO:0009891 (positive regulation of biosynthetic process), GO:0046649 (lymphocyte activation), GO:0000902 (cell morphogenesis), GO:2000026 (regulation of multicellular organismal development), GO:0042127 (regulation of cell population proliferation), GO:0007162 (negative regulation of cell adhesion), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0045595 (regulation of cell differentiation), GO:0009790 (embryo development), GO:1903708 (positive regulation of hemopoiesis), GO:0042246 (tissue regeneration), GO:0080090 (regulation of primary metabolic process), GO:0051128 (regulation of cellular component organization), GO:0031099 (regeneration), GO:0030097 (hemopoiesis), GO:1903055 (positive regulation of extracellular matrix organization), GO:0032967 (positive regulation of collagen biosynthetic process), GO:0002521 (leukocyte differentiation), GO:0051246 (regulation of protein metabolic process), GO:0001944 (vasculature development), GO:0022407 (regulation of cell-cell adhesion), GO:0060284 (regulation of cell development), GO:0010720 (positive regulation of cell development), GO:0010628 (positive regulation of gene expression), GO:0030099 (myeloid cell differentiation), GO:0010468 (regulation of gene expression), GO:0030098 (lymphocyte differentiation), GO:0045637 (regulation of myeloid cell differentiation), GO:0045639 (positive regulation of myeloid cell differentiation), GO:0055021 (regulation of cardiac muscle tissue growth), GO:0032965 (regulation of collagen biosynthetic process), GO:0060420 (regulation of heart growth), GO:0000904 (cell morphogenesis involved in differentiation), GO:0048568 (embryonic organ development), GO:0007399 (nervous system development), GO:1902107 (positive regulation of leukocyte differentiation), GO:0072359 (circulatory system development), GO:1902105 (regulation of leukocyte differentiation), GO:1903053 (regulation of extracellular matrix organization), GO:0022408 (negative regulation of cell-cell adhesion), GO:0042113 (B cell activation), GO:0060043 (regulation of cardiac muscle cell proliferation), GO:0060216 (definitive hemopoiesis), GO:0030162 (regulation of proteolysis), GO:0060232 (delamination), GO:0035162 (embryonic hemopoiesis), GO:0002761 (regulation of myeloid leukocyte differentiation), GO:1903131 (mononuclear cell differentiation), GO:0030183 (B cell differentiation), GO:0002573 (myeloid leukocyte differentiation), GO:0002763 (positive regulation of myeloid leukocyte differentiation), GO:1903317 (regulation of protein maturation), GO:0030851 (granulocyte differentiation), GO:0070613 (regulation of protein processing), GO:0030852 (regulation of granulocyte differentiation), GO:0010755 (regulation of plasminogen activation), GO:0030223 (neutrophil differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex)