Protein: Dolichyl-phosphate-mannose--protein mannosyltransferase (A0A9K3Y6U6)
Organism: Rattus norvegicus (Rat)
Function: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins
Subcellular location: Endoplasmic reticulum membrane; Multi- pass membrane protein. Membrane; Multi-pass membrane protein
InterPro domains:
- IPR027005: O-mannosyl-transferase-like (family) [105-820]
- IPR003342: ArnT-like, N-terminal domain (domain) [133-376]
- IPR032421: Protein O-mannosyl-transferase, C-terminal four TM domain (domain) [611-818]
- IPR016093: MIR motif (domain) [404-591]
- IPR036300: Mir domain superfamily (homologous_superfamily) [402-586]
Sequence:
MFYASGRLLAAREATTLYAPPRARGPALRGKRRELQIPWHLETPSYDSLTGQRTRPGVPPARRVILRKGRMPPAIGGGLAGSELRPRRGRSVQQAARAVSRDVVPEAATRKLKRPAWSSRRFQAAGWWATLAVVTLLSFATRFHRLDQPAHICWDETHFGKMGSYYINRTFFFDVHPPLGKMLIGLAGYLSGYDGTFLFQKPGDRYEHHSYMGMRGFCAFLGSWLIPFAYLTVLDLSKSFPAALLTAALLTCDTGCLTLSQYILLDPILMFFIMAAMLSMVKYNSFANRPFSAPWWFWLSLTGISLAGALGVKFVGLFIIVQVGLNTISDLWHLFGDLSLSLVTVGKHLTARILCLIVLPLVLYVTIFAVHVMVLNKSGPGDGFFSSAFQARLSGNSLHNASIPEHLAYGSVITVKNLRMAIGYLHSHRHLYPEGIGARQQQVTTYLHKDYNNLWIIKKYNTNTDPLDPSFPVEFVRHGDIIRLEHKETTRNLHSHYHEAPLTRKHYQVTGYGINGTGDSNDFWRIEVVNRKFGNRIKVLRSRIRFIHLVTGCVLGSSGKILPKWGWEQLEVTCNPYLKETSNSIWNIEEHINPKLPNISLDVLQPSFPEILLESHMVMIRGNNGLKPKDNEFTSKPWHWPINYQGLRFSGANDTDFRVYLLGNPVVWWLNLVSLVLYLLTGSTIAIAMQRGIQLPAELQGLTKLLLRGGGQLLLGWTLHYFPFFLMGRVLYFHHYFPAMLFSSMLTGLLWDTLLRFCAWALAPSPLGRRIHMVGILSLLLATAYSFYLFHPLAYGMVGPLAQEPESPMAGLRWLESWDF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0048522 (positive regulation of cellular process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009891 (positive regulation of biosynthetic process), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0051246 (regulation of protein metabolic process), GO:1903020 (positive regulation of glycoprotein metabolic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0051247 (positive regulation of protein metabolic process), GO:1903018 (regulation of glycoprotein metabolic process), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0031399 (regulation of protein modification process), GO:2000112 (regulation of cellular macromolecule biosynthetic process), GO:0060049 (regulation of protein glycosylation), GO:0010560 (positive regulation of glycoprotein biosynthetic process), GO:0031401 (positive regulation of protein modification process), GO:0010559 (regulation of glycoprotein biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)