lokahq/bioreason-rl huggingface dataset:
Protein: Annexin (Q8VIN2)
Organism: Rattus norvegicus (Rat)
Function: Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis
InterPro domains:
- IPR037104: Annexin superfamily (homologous_superfamily) [125-463]
- IPR018502: Annexin repeat (repeat) [160-462]
- IPR001464: Annexin (family) [174-461]
- IPR018252: Annexin repeat, conserved site (conserved_site) [177-460]
Sequence:
MSYPGYPPTGYPPFPGYPPAGQESSFPTSGQYPYPSGFPPMGGGAYPPAPSGGYPGAGGYPSPGGYPAPGGYPGTLNPGGPPSYPGGQGFGAPPGGAGFSGYPQPPAQSYGGGPAQVPVPGGFPGGQMPSQYPGGQSPYPGQPAAMTQGTQGTIRPAFNFDAMRDAEILRKAMKGFGTDEQAIVDVVSNRSNDQRQQIKAAFKTMYGKDLIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAIQGAGTQERVLIEILCTRTNQEIRDIVRCYQLEFGRELERDIRSDTSGHFERLLVSMCQGNRDESPSINHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYSMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFTQMYQKTLSTMIASDTSGDYRKLLLAIVGQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0008289 (lipid binding), GO:0005543 (phospholipid binding), GO:0005544 (calcium-dependent phospholipid binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0042221 (response to chemical), GO:0016043 (cellular component organization), GO:1901700 (response to oxygen-containing compound), GO:0010035 (response to inorganic substance), GO:0010033 (response to organic substance), GO:1902074 (response to salt), GO:0010038 (response to metal ion), GO:0051592 (response to calcium ion), GO:0014070 (response to organic cyclic compound), GO:0061024 (membrane organization), GO:0061025 (membrane fusion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0030141 (secretory granule), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0031982 (vesicle), GO:0012506 (vesicle membrane), GO:0030659 (cytoplasmic vesicle membrane), GO:0097708 (intracellular vesicle)
Protein: RCG25530, isoform CRA_c (A6I392)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane; Multi-pass membrane protein. Membrane; Multi- pass membrane protein
InterPro domains:
- IPR002645: STAS domain (domain) [531-741]
- IPR011547: SLC26A/SulP transporter domain (domain) [92-481]
- IPR018045: Sulphate anion transporter, conserved site (conserved_site) [121-142]
- IPR036513: STAS domain superfamily (homologous_superfamily) [511-745]
- IPR001902: SLC26A/SulP transporter (family) [63-742]
Sequence:
MGLPDGSDHGTQQTQALLSATQEMELERRDYHVERPLLNQEQLEDLGHWGPVSKTHPWRTWFRCSRARAKSLLIQHVPVLGWLPRYPVREWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPMFGLYSSFYPVFVYFLFGTSRHISVGTFAVMSVMVGGVTESLTADEAFVQSLNTTVDGARVQVAYTLSFLVGLFQVGLGLVHFGFVVTYLSEPLVRSYTTAASVQVLVSQLKYVFGIKLNSHSGPLSVIYTVLEVCAQLPKTVPGTVVTAIVAGVVLVLVKLLNEKLRRRLPLPIPGELLTLIGATAISYGVKLNDRFKVDVVGNITTGLIPPVAPKTELFATLVGNAFAIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGFFQCFPVSCSMSRSLVQESTGGNTQIAGAVSSLFILLIIVKLGELFRDLPKAVLAAVIIVNLKGMMKQFSDICSLWKANRVDLLIWLVTFVATILLNLDIGLAVSIVFSLLLVVIRMQLPHYSVLGQVPDTDIYRDVAEYSGAKEVPGVKVFRSSATMYFANAELYSDSLKKKCGVDVDRLITQKKKRIKKQEMKIKRMNKAKKSQKQAASSKISSVSVNVNTNFEDIKSNDVEGSEAKVHQGEELEDVVASNQEDAKPPIMTSLKALGLPQPDFHSLILDLSTVSFVDTVCIKSLKNIFRDFREIEVEVYIAACYSPVVTQLEAGHFFDESITKQHVFASVHDAVTFALHHRKSGPKSPVLATKL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901682 (sulfur compound transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015116 (sulfate transmembrane transporter activity), GO:0015103 (inorganic anion transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0048511 (rhythmic process), GO:0022414 (reproductive process), GO:0032504 (multicellular organism reproduction), GO:0042698 (ovulation cycle), GO:0048609 (multicellular organismal reproductive process), GO:0044849 (estrous cycle)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0045177 (apical part of cell), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0016324 (apical plasma membrane)
Protein: Interleukin 9 receptor, isoform CRA_a (A6HDB7)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [140-252]
- IPR003961: Fibronectin type III (domain) [145-254]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [143-262]
- IPR003531: Short hematopoietin receptor, family 1, conserved site (conserved_site) [210-251]
Sequence:
MALGRCFPEGCTVEGAAVKQVSWFLIYSCVCSCVCWGVSVPAQEGGRKAGTFTCFSNSVFRIDCHWSAPEPGSRAWLLFTSNQVTDIKHKCTFWDSRCTLVLPKEEAFLPFDNFTITLHRCVMGQEQVSLVDSQYLPRRHIKLDPPSDLQSNVSSGRCVLTWGISFGLEPLITSLSYELAFKRQEEAWEQARLKDRIVGVTWLVLEAIELNPDTIYEARLRVQMALESYDDKTEGEYYKSHWSEWSQSVSFPSPRRKTQGLLIPRWQGSASILVAVPIFLLLTGLIHFLFRLSPKVKRIFYQNVPSPEAFFHPLYSVYHGDFQTWIGARRAGPQARQDGASAPSGDSESSIWEAIATLTYSPACSVQFPSLKWEATAPGFPGPPGSELVLPAGCLELEGQPSAYLPQEDWAPLGSARPPPLDSDSGSSDYCMLDCREEYDLSVFPEHTLSPEFTLAQPVALAVSSRA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0005488 (binding), GO:0038023 (signaling receptor activity), GO:0005515 (protein binding), GO:0004888 (transmembrane signaling receptor activity), GO:0140375 (immune receptor activity), GO:0019838 (growth factor binding), GO:0019955 (cytokine binding), GO:0004896 (cytokine receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0045927 (positive regulation of growth), GO:0048522 (positive regulation of cellular process), GO:0040008 (regulation of growth), GO:0050794 (regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0001558 (regulation of cell growth), GO:0030307 (positive regulation of cell growth)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009986 (cell surface)
Protein: RCG47968, isoform CRA_a (A6HXG9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm
InterPro domains:
- IPR050281: Flavin monoamine oxidase and related enzymes (family) [80-521]
- IPR002937: Amine oxidase (domain) [81-517]
- IPR036188: FAD/NAD(P)-binding domain superfamily (homologous_superfamily) [79-518]
Sequence:
MYAPSWPKILTLIKVRELTSCHYTLGPPIRQDFWCLESGWVCEIKLGLGLSFNPTLTQQDWKGRWSSLEPSAGQGFVRKRSGVVELGAHWIHGPSQGNPVFQLAAEFGLLGEKELSEENQLVETGGHVALPSVSCTSSGTSVSLELVTEMGSLFYGLIDRTREFLNESETPMASVGEFLKKEISQQVANWTEDENTKRLKLAVLNTFFNIECCVSGTHSMDLVALAPFGEYTVLPGLDCTLSGGYQGLTNCILASLPKEVMVFDKPVKTIHWNGSFQEAAFPGETFPVLVECEDGARLPAHHVIVTVPLGFLKEHQDTFFEPPLPAKKAEAIRKLGFGTNNKIFLEFEEPFWEPDCQFIQVVWEDTSPLQDSPLSLQDTWFKKLIGFLVLPSFESSHVLCAFIAGLQSEFMETLSDEEVLLSLTQVLRRVTGNPQLPAAKSVLRSRWHSAPYTRGSYSYVAVGSTGDDLDLMAQPLPADGTGTQLQVLFAGEATHRTFYSTTHGALLSGWREADRLIGLWDSQAEQSRPRL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016645 (oxidoreductase activity, acting on the CH-NH group of donors), GO:0016647 (oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901575 (organic substance catabolic process), GO:0009308 (amine metabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0006576 (biogenic amine metabolic process), GO:0009310 (amine catabolic process), GO:0042402 (cellular biogenic amine catabolic process), GO:0006595 (polyamine metabolic process), GO:0009445 (putrescine metabolic process), GO:0008216 (spermidine metabolic process), GO:0006598 (polyamine catabolic process), GO:0008215 (spermine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0043229 (intracellular organelle), GO:0042579 (microbody), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0031907 (microbody lumen), GO:0070013 (intracellular organelle lumen), GO:0043231 (intracellular membrane-bounded organelle), GO:0005777 (peroxisome), GO:0005782 (peroxisomal matrix)
Protein: Protein amnionless (A6KBQ1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein
InterPro domains:
- IPR026112: Amnionless (family) [1-458]
Sequence:
MGALGRVLLWLQLCALTRAAYKLWVPNTSFDTASNWNQNRTPCAGDAVQFPADKMVSVLVRDSHAISDMLLPLNGEFVLASGAAFSAAGGDSDPACNPGAPLLFRNPDRFSWLDPHLWSSGTQESGIFFVDAERVPCTYDDVLFPRNGSFRVALGPGPNPVHVRSVSAVGQTFTRDEDLAAFLASREGRLRFHGSGALRVGSQACTDATGCVCGNAETLPWICASLLQPLGGRCPEATCQDPVRPQGQCCDLCGAIVSLTHDPTFDLERYRARLLDLFLKQPQYQGLQVAVSKVLRDAHTEIQVVLLETRPATGAAGQLGHALLQDAVAQGSVLGIVSATLRQSGKPTAANSALDQNGSGAGLAGGVAAVVLLALVGTVLLLLHRSGRLRWRRHGDAEPTSAGLPLGFRNPIFDVMVFKQQQASVEFADSTQKVDILDIDTNFGCFVNPLFAGEAEAEA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0038024 (cargo receptor activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0032501 (multicellular organismal process), GO:0051641 (cellular localization), GO:0003008 (system process), GO:0033036 (macromolecule localization), GO:0003014 (renal system process), GO:0070727 (cellular macromolecule localization), GO:0070293 (renal absorption), GO:0008104 (protein localization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0098862 (cluster of actin-based cell projections), GO:0098590 (plasma membrane region), GO:0120025 (plasma membrane bounded cell projection), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005903 (brush border), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0031526 (brush border membrane), GO:0030139 (endocytic vesicle), GO:0031253 (cell projection membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)
Protein: Nicotinamide-nucleotide adenylyltransferase (A6I2B1)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR045094: Nicotinamide/nicotinate mononucleotide adenylyltransferase, eukaryotic (family) [7-232]
- IPR004821: Cytidyltransferase-like domain (domain) [10-206]
- IPR014729: Rossmann-like alpha/beta/alpha sandwich fold (homologous_superfamily) [4-245]
- IPR051182: Eukaryotic NMN adenylyltransferase (family) [2-237]
- IPR005248: Nicotinate/nicotinamide nucleotide adenylyltransferase (family) [10-232]
Sequence:
MKNRIPVVLLACGSFNPITNMHLRLFEVARDHLHQTGKYQVIEGIISPVNDSYGKKDLVASHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHGELLRSVAQMDGPDPSKIPSASAALPELKLLCGADVLKTFHTPNLWKDSHIQEIVEKFGLVCVNRSGHDPKRYILDSPILQQFQHNIHLAREPVLNEISATYVRKALSQGQSVKYLLPEAVITYIRDQGLYINDSSGKGKGKTG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016779 (nucleotidyltransferase activity), GO:0070566 (adenylyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:0034097 (response to cytokine), GO:0034612 (response to tumor necrosis factor)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0036477 (somatodendritic compartment), GO:0042995 (cell projection), GO:0044297 (cell body), GO:0043025 (neuronal cell body), GO:0120025 (plasma membrane bounded cell projection), GO:0043005 (neuron projection), GO:0030424 (axon)
Protein: Transforming growth factor, beta induced (A6KAM3)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR036378: FAS1 domain superfamily (homologous_superfamily) [1-461]
- IPR000782: FAS1 domain (domain) [1-461]
- IPR050904: Cell adhesion and biosynthesis-related protein (family) [1-424]
Sequence:
MVDRRVLTDELKHGMALTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVISTVTNNIQQIIEIEDTFETLRAAVAASGLNTVLEGDGQFTLLAPTNEAFEKIPAETLNRILGDPEALRDLLNNHILKTAMCAEAIVAGMAMETLGGTTLEVGCSGDMLTINGKAVISNKDILATNGVIHFIDELLIPDSAKTLLELASESDVSTAIDLLRQAGLSTHLSGKEQLTFLAPLNSVFKDGVPRIDGQMKTLLLNHMVKGQLASKYLYSGQTLDTLGGKKLRVFVYRNSLCIENSCIAAHDKKGRYGTLFTMDRMLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLMETLNREGVYTVFAPTNEAFQAMPPEELNKLLANAKELTNILKYHIGDEILVSGGIGALVRLKSLQGDKLEVSSKNNVVSVNKEPVAETDIMATNGVVYAINTVLQPPANRPQERGEELADSALEIFKKASAYSRSAQSSMRLAPVYQRLLERMKRRG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0046906 (tetrapyrrole binding), GO:0020037 (heme binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009888 (tissue development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0001501 (skeletal system development), GO:0051216 (cartilage development), GO:0061448 (connective tissue development), GO:0002062 (chondrocyte differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062023 (collagen-containing extracellular matrix), GO:0005604 (basement membrane)
Protein: TG interacting factor, isoform CRA_b (A6KF88)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR008422: KN homeodomain (domain) [54-93]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [36-108]
- IPR050224: Three Amino acid Loop Extension (TALE) homeobox (family) [22-120]
- IPR001356: Homeodomain (domain) [34-101]
Sequence:
MKSKKGVVAAASGSDSEDEDSMDSPLDLSSSAASGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFTISRRGAKISEASSIEAAMGIKNFMPTLEESPFHSCVVGPNPTLGRPVSPKPPSPGPILARPSVICHTTVTALKDGPFSLCQAVSVGHSTDVQQVAPSNFTDASLRYPEDTCKSGPSPNPQSGLFNTPPPTPPDLNQDFSGFQLLVDVALKQAAEMELQAKLTA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0046332 (SMAD binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0009719 (response to endogenous stimulus), GO:0009892 (negative regulation of metabolic process), GO:0071495 (cellular response to endogenous stimulus), GO:0060255 (regulation of macromolecule metabolic process), GO:0009410 (response to xenobiotic stimulus), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0070848 (response to growth factor), GO:0010629 (negative regulation of gene expression), GO:0071363 (cellular response to growth factor stimulus), GO:0010468 (regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Carbonic anhydrase (A6J5I4)
Organism: Rattus norvegicus (Rat)
Function: Reversible hydration of carbon dioxide
InterPro domains:
- IPR023561: Carbonic anhydrase, alpha-class (family) [5-181]
- IPR018338: Carbonic anhydrase, alpha-class, conserved site (conserved_site) [29-45]
- IPR036398: Alpha carbonic anhydrase domain superfamily (homologous_superfamily) [1-198]
- IPR001148: Alpha carbonic anhydrase domain (domain) [1-187]
Sequence:
MYIQGLQPHQYRAEQLHLHWGNRNDPHGSEHTVSGKHFAAELHIVHYNSDLYSDFGSASDKSEGLAVLAVLIEIGSVNPSYDKIFSHLQHVKYKGQQVLIPGFNIEELLPESPGEYYRYEGSLTTPPCYPTVLWTVFRNPVQISQEQLLALETALYFTHMDDPSPREMVNNFRQVQKFDERLVYISFRQGLLTDTGLSLGIILSVALAGVLGISIVLAVSVWLFKRKKSKKGDNKGVIYKPAIKKEAEVHA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016835 (carbon-oxygen lyase activity), GO:0016836 (hydro-lyase activity), GO:0004089 (carbonate dehydratase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0048511 (rhythmic process), GO:0022414 (reproductive process), GO:0032504 (multicellular organism reproduction), GO:0042698 (ovulation cycle), GO:0048609 (multicellular organismal reproductive process), GO:0044849 (estrous cycle)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0045178 (basal part of cell), GO:0045177 (apical part of cell), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0009925 (basal plasma membrane), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0016324 (apical plasma membrane), GO:0016323 (basolateral plasma membrane)
Protein: Synaptophysin-like protein, isoform CRA_c (A6HB73)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
- IPR008253: Marvel domain (domain) [10-218]
- IPR001285: Synaptophysin/synaptoporin (family) [2-240]
Sequence:
MSTFQINLNPLKEPLGFIKILEWFASIFAFATCGGFKGKTEIQVNCLSAPGENKTITATFGYPFRLNQASFHSAPNVNVCKVNWEKHVLIGDYSSSAQFYVTFAVLVFLYCIAALLLYVGYTNLYRDSRKLPMIDFIVTLVATFLWLVSSSAWAKALTDIKVATGHRIVEELDPCKSEVSCYFVSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSASHGQGGVPPTSGM
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0019904 (protein domain specific binding), GO:0000149 (SNARE binding), GO:0019905 (syntaxin binding), GO:0017075 (syntaxin-1 binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0007272 (ensheathment of neurons), GO:0048731 (system development), GO:0008366 (axon ensheathment), GO:0042552 (myelination), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0098793 (presynapse), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0030054 (cell junction), GO:0031090 (organelle membrane), GO:0008021 (synaptic vesicle), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0043227 (membrane-bounded organelle), GO:0030133 (transport vesicle), GO:0070382 (exocytic vesicle), GO:0030672 (synaptic vesicle membrane), GO:0030658 (transport vesicle membrane), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0031982 (vesicle), GO:0012506 (vesicle membrane), GO:0030659 (cytoplasmic vesicle membrane), GO:0099501 (exocytic vesicle membrane), GO:0097708 (intracellular vesicle)
Protein: Elastase 2, neutrophil (Predicted) (A6K8V8)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR050850: Peptidase S1 family, Elastase subfamily (family) [29-251]
- IPR043504: Peptidase S1, PA clan, chymotrypsin-like fold (homologous_superfamily) [33-246]
- IPR009003: Peptidase S1, PA clan (homologous_superfamily) [19-251]
- IPR033116: Serine proteases, trypsin family, serine active site (active_site) [200-211]
- IPR001254: Serine proteases, trypsin domain (domain) [32-251]
- IPR001314: Peptidase S1A, chymotrypsin family (family) [59-211]
- IPR018114: Serine proteases, trypsin family, histidine active site (active_site) [69-74]
Sequence:
MQPTMALHRPSNQTLASMLLALLLVCPALASEIVGGRPAQPHAWPFMVSLQRRGGHFCGATLIARNFVMSAAHCVNGRNFQSVQVVLGAHDLRRREPTRQIFSVQRIFENGFDPSRLLNDIVIIQLNGSATINANVQVAELPAQGQGVGNRTPCVAMGWGRLGTNRPLPSVLQELNVTVVTNLCRRRVNVCTLVPRRQAGICFGDSGGPLVCNNLVQGIDSFIRGGCGSGFYPDAFAPVAEFADWINSIIRSHDDRPLTNPKDREREGRTN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0048870 (cell motility), GO:0050900 (leukocyte migration), GO:0050794 (regulation of cellular process), GO:0002682 (regulation of immune system process), GO:0006950 (response to stress), GO:0040012 (regulation of locomotion), GO:0048522 (positive regulation of cellular process), GO:2000145 (regulation of cell motility), GO:0002523 (leukocyte migration involved in inflammatory response), GO:0002685 (regulation of leukocyte migration), GO:0006952 (defense response), GO:0030155 (regulation of cell adhesion), GO:0045785 (positive regulation of cell adhesion), GO:0016477 (cell migration), GO:0006954 (inflammatory response), GO:0022409 (positive regulation of cell-cell adhesion), GO:0022407 (regulation of cell-cell adhesion), GO:0002691 (regulation of cellular extravasation), GO:0030334 (regulation of cell migration), GO:1903236 (regulation of leukocyte tethering or rolling), GO:1903037 (regulation of leukocyte cell-cell adhesion), GO:1903039 (positive regulation of leukocyte cell-cell adhesion), GO:1904996 (positive regulation of leukocyte adhesion to vascular endothelial cell), GO:1904994 (regulation of leukocyte adhesion to vascular endothelial cell)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062023 (collagen-containing extracellular matrix)