Protein: G protein-coupled receptor kinase (A0A8M2BEP6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [306-318]
- IPR000719: Protein kinase domain (domain) [185-447]
- IPR000961: AGC-kinase, C-terminal (domain) [448-527]
- IPR036305: RGS domain superfamily (homologous_superfamily) [31-180]
- IPR000239: GPCR kinase (family) [166-517]
- IPR017441: Protein kinase, ATP binding site (binding_site) [191-223]
- IPR044926: RGS, subdomain 2 (homologous_superfamily) [74-152]
- IPR016137: RGS domain (domain) [52-170]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [183-534]
Sequence:
MELENIVANTVLLKAREGGGGKRKGRSKKWREILRFPHISQCTELNKAIERDYVCLCERQPIGRLLFRLYCETQPELQRCIQLLDAMDDYEVSPDEKRKSRGDEIIKKFLNKQSSECVDVAESLAERCKENLELSPCKEIFSDCRKALHDYLSGAPFTDYQNSMYFDRFLQWKMLERQPITKDTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNMGTPGFEKERVQLYAAEICCGLEDLHRESIIYRDLKPENILLDDNGHIRISDLGLAIKVPDGEQIRGRVGTVGYMAPEVINNERYSMSPDWWGLGCLIYEMTAGRSPFRARKERVKREDVEKRVQEEEEEYSDKFSEDTKAICRMLLSKDPKQRLGCQTDRASGVKAHPFFKNINFKRLEAGILEPSFVPDPRAVYCKDVLDIEQFSTVKGVNLDQTDNDFYSKFATGSVSIPWQNEMIETECFNDLNVFGPQGTRPPDLDWNQPPEPPRRSLLDRIFRRHRPEVTITQSRVLSSSVNSVDSVTNSAP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0048519 (negative regulation of biological process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0023057 (negative regulation of signaling), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0007389 (pattern specification process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0035295 (tube development), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0048729 (tissue morphogenesis), GO:0009888 (tissue development), GO:0003002 (regionalization), GO:0010646 (regulation of cell communication), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009966 (regulation of signal transduction), GO:0009799 (specification of symmetry), GO:0009790 (embryo development), GO:0051128 (regulation of cellular component organization), GO:0044087 (regulation of cellular component biogenesis), GO:0035239 (tube morphogenesis), GO:0009855 (determination of bilateral symmetry), GO:0060562 (epithelial tube morphogenesis), GO:0048568 (embryonic organ development), GO:0003007 (heart morphogenesis), GO:0031344 (regulation of cell projection organization), GO:0060972 (left/right pattern formation), GO:0035050 (embryonic heart tube development), GO:0048562 (embryonic organ morphogenesis), GO:0072359 (circulatory system development), GO:0007507 (heart development), GO:0033043 (regulation of organelle organization), GO:0003143 (embryonic heart tube morphogenesis), GO:0002009 (morphogenesis of an epithelium), GO:1902532 (negative regulation of intracellular signal transduction), GO:0060429 (epithelium development), GO:1902115 (regulation of organelle assembly), GO:1902531 (regulation of intracellular signal transduction), GO:0060491 (regulation of cell projection assembly), GO:0031016 (pancreas development), GO:0061371 (determination of heart left/right asymmetry), GO:0032006 (regulation of TOR signaling), GO:0007368 (determination of left/right symmetry), GO:0120032 (regulation of plasma membrane bounded cell projection assembly), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0032007 (negative regulation of TOR signaling), GO:1902017 (regulation of cilium assembly), GO:0001947 (heart looping)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)