lokahq/bioreason-rl huggingface dataset:
Protein: 2-oxoglutarate dehydrogenase complex component E1 (A0A8M3AVG6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Mitochondrion. Nucleus
InterPro domains:
- IPR029061: Thiamin diphosphate-binding fold (homologous_superfamily) [228-886]
- IPR031717: 2-oxoglutarate dehydrogenase E1 component/KDG, C-terminal (domain) [883-1028]
- IPR001017: Dehydrogenase, E1 component (domain) [272-596]
- IPR032106: 2-oxoglutarate dehydrogenase E1 component, N-terminal domain (domain) [49-87]
- IPR011603: 2-oxoglutarate dehydrogenase E1 component (family) [47-1029]
- IPR042179: Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily (homologous_superfamily) [797-1026]
- IPR005475: Transketolase-like, pyrimidine-binding domain (domain) [665-879]
Sequence:
MHRLRTCAARLRPITASQTAKNLSQQGPAATPRTFQPLRCFSSPVAAEPFLNGTSSNYVEEMYYAWLENPKSVHKSWDIFFRNANAGAPPGTAYQSPPPLGVSLAGLAQAQSLVGAQPNVEKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGIMDADLDSCVPTDIITSSDKLDLTHVKKRLSALTIGGFYGLEESDLDKVFRLPTTTFIGGDESALPLREIIRRLEMAYCQHIGVEFMFINDLDQCQWIRQKFERPGVMQFSLEEKRTLLARMVRSTRFEEFLQRKWSSEKRFGLEGCESLIPALKTIIDKSSENGVDTVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAADEGSGDVKYHLGMYHRRINRVTNRNITLSLVANPSHLEAVNPVVQGKTKAEQFYSGDTDGKRVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVANNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVMYVCNVAAEWRATFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIKKQKGVLQKYAEKLIAEGAVTRQEYEEEIAKYDKICEEAHSRSKDEKILHIKHWLDSPWPGFFTLDGQPKSISCPSTGLPEEELAQIGQVASSVPVEDFTIHGGLSRILKGRGDMIKNRTVDWALGEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQNVDKRICIPMNHMSPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDFNPKITDDFDVRQLYDCNWIVVNCSNPANYFHVIRRQILLPFRKPLIVFTPKSLLRHPEAKSNFDQMLPGTHFQRVITDDGPPAQNPSEVKRIVFCTGKIYYELTRERKARNMENSVAITRIEQLSPFPFDLVRAETEKFPNADLVWCQEEHKNQGYYDYVKPRMRTTINRTKPVWYAGREPAAAPATGNKNTHLLELKRFLDTAFNLDAFKDHI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016903 (oxidoreductase activity, acting on the aldehyde or oxo group of donors), GO:0016620 (oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0003008 (system process), GO:0003013 (circulatory system process), GO:0008015 (blood circulation), GO:0003015 (heart process), GO:0060047 (heart contraction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (A0A8M3B8G4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
Sequence:
MACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINALHKPAYEHPKDLKASSGRLRVGYISSDFGNHPTSHLMQSIPGMHNSEKFEVFCYALSPDDGTNFRVKVMAEAHHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGAPFMDYIVSDKATSPIEVAEQYSEKLAYMPNTFFIGDHANMFPHLKKKAVIDFKSNGHIFDNRIVLNGIDLKAFLESLPDVKVVKMECDGQEVADSNGALSMPIIPMNTAAEAIINMINQGQIQVTINGFTVSNGLATTQIFTVEEVVVSGTVALQINNKAATGEEVPRTIVVTTRSQYGLPEDSIVYCNFNQLYKIDPPTLQMWANILKRVPNSVIWLLRFPAVGEPNIQQYAQNLGLPASRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCPELIAQSRQEYEDVAVKLGTDMEFLKKVRARVWKQRICSPLFNTKQYTMDLEKLYLQMWENHASGGKPDHLVKMQSLETSEST
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016262 (protein N-acetylglucosaminyltransferase activity), GO:0016758 (hexosyltransferase activity), GO:0008194 (UDP-glycosyltransferase activity), GO:0008375 (acetylglucosaminyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0070085 (glycosylation), GO:0044249 (cellular biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0043413 (macromolecule glycosylation), GO:1901135 (carbohydrate derivative metabolic process), GO:0019538 (protein metabolic process), GO:0036211 (protein modification process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0009059 (macromolecule biosynthetic process), GO:0006486 (protein glycosylation), GO:0043412 (macromolecule modification), GO:0034645 (cellular macromolecule biosynthetic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0009100 (glycoprotein metabolic process), GO:0009101 (glycoprotein biosynthetic process), GO:0006493 (protein O-linked glycosylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Krueppel-like factor 3 isoform X1 (A0A8M6YYM0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [256-324]
- IPR013087: Zinc finger C2H2-type (domain) [242-324]
Sequence:
MLTCDPKPDMSLYQPYSTLIKSHETFGMVLPPAVVSGAHLYPSHYHPSYQLPYSHRQSQDVHQAQIEPVDLSIGNKSSGSSPSSSLASSSPRASPPSPYEAHSPASRCSQNRQLSPSLTLPIPAVTQVLTPFVSSPGMIPVIPMPLSVLYPPSLHLSPSIIISPVTPEDPANHKHFSVIKSENTSDHHELLKPIKSEPHPEHTQDNHSQEKSVITALPNYNEGNTQSPKVESPDLLKKRRIHRCDFNGCNKVYTKSSHLKAHRRTHTGEKPYKCMWEGCTWKFARSDELTRHYRKHTGVKPFHCPDCDRTFSRSDHLALHKKRHLLV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0003682 (chromatin binding), GO:0003700 (DNA-binding transcription factor activity), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific), GO:0001217 (DNA-binding transcription repressor activity), GO:0001227 (DNA-binding transcription repressor activity, RNA polymerase II-specific)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0042592 (homeostatic process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0021700 (developmental maturation), GO:0048871 (multicellular organismal-level homeostasis), GO:0002262 (myeloid cell homeostasis), GO:0034101 (erythrocyte homeostasis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048469 (cell maturation), GO:0071695 (anatomical structure maturation), GO:0048872 (homeostasis of number of cells), GO:0043249 (erythrocyte maturation), GO:0030097 (hemopoiesis), GO:0030218 (erythrocyte differentiation), GO:0030099 (myeloid cell differentiation), GO:0061515 (myeloid cell development), GO:0048821 (erythrocyte development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Cyclin-Y isoform X2 (A0A8M1RI35)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR013763: Cyclin-like domain (domain) [182-267]
- IPR006671: Cyclin, N-terminal (domain) [174-274]
- IPR036915: Cyclin-like superfamily (homologous_superfamily) [182-274]
- IPR012399: Cyclin Y (family) [1-350]
Sequence:
MGNSTSCCVSSSPKLRRNAHSRLEPYRPEPELSREDTGCNLQHISDRENIDELNMEYNPSDHPRASTIFLSKSQTDVREKRKSLYVNHLTHIAESKQHPSGPMRRKYSSCSTIFLDDSTVSQPNLKYTIKCVALAIYYHIKNRNVDGRMLLDIFDEKLHPLSKSEVPSDYDKHDPEQKQIYRFVRTLFSAAQLTAECAIVTLVYLERLLTYAEIDICPANWKRIVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNELERQFLELLQFNINVPSSVYAKYYFDLRSLSEANNLSFPLEPLSRDKAQKLEAISRLCDDKYKDLRKAAKKRSVSADNLSVVRWSPAIIS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0009620 (response to fungus), GO:0043207 (response to external biotic stimulus), GO:0001878 (response to yeast)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:1990234 (transferase complex), GO:0061695 (transferase complex, transferring phosphorus-containing groups), GO:1902911 (protein kinase complex), GO:1902554 (serine/threonine protein kinase complex), GO:0000307 (cyclin-dependent protein kinase holoenzyme complex)
Protein: Catenin delta-2 isoform X8 (A0A8M3B7R7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR000225: Armadillo (repeat) [506-954]
- IPR028435: Plakophilin/Delta catenin (family) [48-994]
- IPR011989: Armadillo-like helical (homologous_superfamily) [476-973]
- IPR016024: Armadillo-type fold (homologous_superfamily) [476-959]
Sequence:
MPVPDQPSGTENSSMLSPVLNASNGDGSETETTSAILASVKEQELQFERLTRELEAERQIVATQLERCKLGSETGSMSSISSADEKFRWNNQDGQKDIEEELTTGLELVDSCIRSLQESGILDSQEFTAGERPGILSQSALQLNNQEGTFPYPVSYHSNQTLALGDLSASQPPRSGQALGSPSKLQRLGSASDMPSYATLARVSSPKQSPSRLAKSYSTSSPINMAAGGGSSSSPLHMAGAGNVSNSSPLHQLSAAVGSYATLSPTKRMLHTTDQYKISHDLYANATLQRPGSLAGSRGSYSSQHSHLGSELRPLQSPEHHIDPIYEDRVYQKAPLRNFNQAQDPMNQFCDQVLNFLLCPYSPVIAPSSPGVDSIPLQRTGSQNATGTFPRAGYATGPGASTADYANPYRTLQFCPSTDSPYSKSGPALPPEATLVRSPSVDSIQKDPRYDPEFLVWNQNQAEQRMTKEFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKSEIRRQGGIQLLVDLLDHRMTDVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDVEIRELLTGVLWNLSSCDALKMPIIQDALAVLTNTVIIPHSGWDTSPLQDDRKLHLHSSQVLRNATGCLRNVSSAGEEARRRMRECEGLTDALLYVIQTALGTSEIDSKTIENCVCILRNLSYRLAAETSQGQQMGSEELDGVLCTDASGKDAESSGCWGKKKKKKKSHDQWDGVGPFPDSSDPPKGLQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKVGPTLKPWSVYIRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNNNSTGTGGSSKSMSDDTITAICCALHEVITKNMENTKALRDAGGIEKLIGIARSKGDKHTPKVVKAASQVLNSMWQYRDLRSLYKKDGYSQYHFVGSSSTIERDRQRPYSSSRTPSISPVRTSPNNRSASAPTSPREMMSLKERKTDYESTGSNSTYHGNKGEHTSRKDAMAAQISSGTSTLFRGAYMSPADDIKHNQVSAQGNPPEAYPPFQTPPGANFEEPYYEDQAHKRPPPAADGTMHLGLKSTGNYVDFYSASRPYSELNYETSHYPASPDSWV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048870 (cell motility), GO:0030154 (cell differentiation), GO:0016477 (cell migration), GO:0048731 (system development), GO:0001764 (neuron migration), GO:0022008 (neurogenesis), GO:0007399 (nervous system development), GO:0048699 (generation of neurons)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction), GO:0070161 (anchoring junction), GO:0005911 (cell-cell junction), GO:0005912 (adherens junction)
Protein: 2-oxoglutarate dehydrogenase complex component E1 (A0A8M9PUH2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Mitochondrion. Nucleus
InterPro domains:
- IPR029061: Thiamin diphosphate-binding fold (homologous_superfamily) [211-869]
- IPR031717: 2-oxoglutarate dehydrogenase E1 component/KDG, C-terminal (domain) [866-1011]
- IPR001017: Dehydrogenase, E1 component (domain) [255-579]
- IPR032106: 2-oxoglutarate dehydrogenase E1 component, N-terminal domain (domain) [52-90]
- IPR011603: 2-oxoglutarate dehydrogenase E1 component (family) [49-1012]
- IPR042179: Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily (homologous_superfamily) [874-1014]
- IPR005475: Transketolase-like, pyrimidine-binding domain (domain) [648-862]
Sequence:
MHRLRTCAARLRPLTASQNAASFSQHRPAVVHGARRTFQPIRNYTAPVTAEPFLNGTSSNYLEEMYYAWLEDPKSVHKSWDIFFRNANAGVAPGSAYQSVPPMGLSGLSQSQALIGAQPNVEKLVEDHLAVQSLIRAYQVRGHHIAKLDPLGISCVNFDNAPITVGLHQSGFYGLEETDLDKVFRLPTTTFIGGSETALPLREIIHRLEMAYCQHIGVEFMFINDLEQCQWIRQKFEKPGVMQFTLDEKRTLLARMVRSTRFEEFLQRKWSSEKRFGLEGCESLIPALKTIIDKSSENGVENVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAADEGSGDVKYHLGMYHRRINRVTERQITLSLVANPSHLEAVDPVVQGKTKAEQFYCGDTDGNRVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTIHVVANNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVMYVCNVAAEWRATFHKDVVVDLVSYRRNGHNEMDEPMFTQPLMYKQIKKQKPVLQKYAEKLIAEGAVTRQEYEEEISKYDKICEEAYNRSKDEKIMHIKHWLDSPWPGFFTLDGQPKTMSCPSTGLSEETLAHIGQTASSVPVEDFTIHGGLSRILKSRSLMVQNRSVDWALGEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNYMDPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVFPKITEDFAVRQLYDCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFEEMLPGTHFSRLIPEQGSASQSAAGVQHLIFCTGKVFYDLQRERKSRGLEERVAISRIEQLSPFPFDLVKAEAEKYPHAHLLWCQEEHKNQGYYDYVKPRISTTLNNTRPVWYVGRDPAAAPATGNKKAHLLELQRFLDTAFNLEAFQSAS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016903 (oxidoreductase activity, acting on the aldehyde or oxo group of donors), GO:0016620 (oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0003008 (system process), GO:0003013 (circulatory system process), GO:0008015 (blood circulation), GO:0003015 (heart process), GO:0060047 (heart contraction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: mitogen-activated protein kinase kinase (A0A8M2BK72)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [308-320]
- IPR017441: Protein kinase, ATP binding site (binding_site) [191-214]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [180-463]
- IPR000719: Protein kinase domain (domain) [185-450]
Sequence:
MRMCPALRMRTAAYREFWRTWQPPRLLQKLLSASEASITAGGWGAHRCSGRSSRVACASETVAENRAREGGLRRSTMAAPSSDSGSSCGGGGTAGPAGLSPRLGSIGAQDSNSCWRCQNETVKRKALKLNFANPPVKPAARLPITSTAPAFQNPHIERLRTHSIESSGKLKISPEQHCDFTAEDLKDLGEIGRGAYGSVNNMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMATSLDKFYKYVYCASDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRNGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPRWNSVFDQLTQVVKGEPPQLCSSEDRQFSHKFIQFVNLCLTKDESKRPKYRELLKHPFILMYEERLVDVARYVCRILDQMPASPGSPMYVD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004712 (protein serine/threonine/tyrosine kinase activity), GO:0016301 (kinase activity), GO:0004708 (MAP kinase kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009888 (tissue development), GO:0009790 (embryo development), GO:0048598 (embryonic morphogenesis), GO:0048729 (tissue morphogenesis), GO:0060429 (epithelium development), GO:0007369 (gastrulation), GO:0060027 (convergent extension involved in gastrulation), GO:0002009 (morphogenesis of an epithelium), GO:0060026 (convergent extension)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Bromodomain-containing protein 3 isoform X4 (A0A8M2B835)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR001487: Bromodomain (domain) [28-401]
- IPR050935: Bromodomain-containing chromatin reader (family) [7-652]
- IPR036427: Bromodomain-like superfamily (homologous_superfamily) [14-406]
- IPR043508: Brdt, bromodomain, repeat I (domain) [30-136]
- IPR018359: Bromodomain, conserved site (conserved_site) [52-374]
- IPR027353: NET domain (domain) [537-619]
- IPR043509: Brdt, bromodomain, repeat II (domain) [295-396]
- IPR038336: NET domain superfamily (homologous_superfamily) [539-619]
Sequence:
MSAVTSATPEPPAAANPPPPEVINPTKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAVKLGLPDYHKIIKNPMDMGTIKKRLESVYYYSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVALMPQEEVELLPPAPKGKGRKPAGPGQQDGAVSTGSPTSVFPGATSPSSQTAVVSPAPVPAITPSIPAVQNTTAAAVIPSMPPSQPTVKKKGVKRKADTTTPTTSAITASRSQSPTPILEGKQSKVAARRESTGRPIKPPKKDFEDGELGVHGGKKGRLSEQLKYCDVILKEMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKKKMDSREYQDAQTFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPVEVPGAGGVGGAGVVSKSTVSSESSGDSSTSDSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVSKPKKKKEKKEKDKKKKENKHNKSKPEEKAKPGQPPKPAQQKKGPTRKANSTVPGNRQPKKGGRGPGYESDEEMSLPMTYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPSTLRELERYVKSCLQKKQRKPPQKGGSGPSRLSGSSSSSDSGSSSSSGSTSDSSDSD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding), GO:0005515 (protein binding), GO:0042393 (histone binding), GO:0140030 (modification-dependent protein binding), GO:0140033 (acetylation-dependent protein binding), GO:0070577 (lysine-acetylated histone binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0030154 (cell differentiation), GO:0048468 (cell development), GO:0030097 (hemopoiesis), GO:0030099 (myeloid cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus), GO:0005694 (chromosome), GO:0000793 (condensed chromosome)
Protein: Inositol polyphosphate-5-phosphatase K isoform X2 (A0A8M3B177)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR036691: Endonuclease/exonuclease/phosphatase superfamily (homologous_superfamily) [63-416]
- IPR046985: Inositol 5-phosphatase (family) [34-473]
- IPR000300: Inositol polyphosphate-related phosphatase (domain) [83-407]
- IPR041611: SKICH domain (domain) [412-512]
Sequence:
MSSSMEEISEYFSEKLQRQRSDSAASSSTQSTSSRQHVRQRLAMLLTCVDDLDTDHKLQTQVAKTLDEAFLVCRQIAGRPKKNPFRLYVVTWNVATAEPPDDVNALLQLNSPKKPDLYVIGLQEVRAAPLKFVSDLAFEDSWSHLFMDTLSPLHYIKVSSIRMQGLLLLFFSKLEHVPFIRDIQVTYTRTGLYGYWGNKGGVTIRLSFYGHMLCFLNCHLTAHMNYASQRVDEFEHILDAQNFNTKNTPHVLDHKVVFWFGDLNFRIEDHGMLFVRNCITSQRFNLLWPKDQLTMMKQKEVILQKFEEGPLDFQPTYKFDLNSDNYDTSGKKRKPAWCDRILWRVKPKASLTENTNEEEPEKQQEEEREDEFPLKMTQEYYTSKMEYGISDHKPVIGIFRLELRKMYETPLVQVFAEGEWSADFDAVITYRLLQAFASSAWDWIGLYKVGFKSVSDYITYAWVKDDQVSFNEELFQVYMNKDEIPVLGGECVLCYYSSNLQCIVGISQPFKVQESRAAIEEGLVPENINGLNQALAS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0016791 (phosphatase activity), GO:0052866 (phosphatidylinositol phosphate phosphatase activity), GO:0034595 (phosphatidylinositol phosphate 5-phosphatase activity), GO:0034594 (phosphatidylinositol trisphosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0061061 (muscle structure development), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007517 (muscle organ development), GO:0042692 (muscle cell differentiation), GO:0048880 (sensory system development), GO:0055001 (muscle cell development), GO:0060537 (muscle tissue development), GO:0007423 (sensory organ development), GO:0007519 (skeletal muscle tissue development), GO:0060538 (skeletal muscle organ development), GO:0150063 (visual system development), GO:0014904 (myotube cell development), GO:0001654 (eye development), GO:0051146 (striated muscle cell differentiation), GO:0014902 (myotube differentiation), GO:0043010 (camera-type eye development), GO:0048741 (skeletal muscle fiber development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)