Protein: 11-cis retinol dehydrogenase isoform X2 (A0A8M2BLL9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR002347: Short-chain dehydrogenase/reductase SDR (family) [38-222]
- IPR020904: Short-chain dehydrogenase/reductase, conserved site (conserved_site) [171-199]
- IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [35-275]
Sequence:
MYEFLSCPSTYALGTFAILWVLVWFYRDNLKITRVSEKHVFVTGCDSGFGNLLCKRLDKRGFRVLAGCLTEKGADDLKRAAGPFLKTCILDVTSSASIQKAMEWTKKEVGDKGLWGLVNNAGRSLPMGPSEWMKIEDFESTLKVNMTGVIETTMTFLPLVKKARGRVVNVASVLGRVAANGGGYCISKFAVESFSDCLRRDIQGFGVNVCIIEPGFFKTQVTSLEPIERELHRLWNQLTPEVKESYGDKYLDKYIWIQRLIMNAICDSDLSKVTNCMEHALLAVHPRTRYSAGWDAKFLWIPLSYMPACFVDIALKLVMPKPAKGV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor), GO:0004745 (NAD-retinol dehydrogenase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009058 (biosynthetic process), GO:0009653 (anatomical structure morphogenesis), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0009887 (animal organ morphogenesis), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006766 (vitamin metabolic process), GO:0060041 (retina development in camera-type eye), GO:0022008 (neurogenesis), GO:0006720 (isoprenoid metabolic process), GO:0007399 (nervous system development), GO:0009110 (vitamin biosynthetic process), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0090596 (sensory organ morphogenesis), GO:0008299 (isoprenoid biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0030182 (neuron differentiation), GO:0006775 (fat-soluble vitamin metabolic process), GO:0042362 (fat-soluble vitamin biosynthetic process), GO:0048592 (eye morphogenesis), GO:0001654 (eye development), GO:0048699 (generation of neurons), GO:0046530 (photoreceptor cell differentiation), GO:0006721 (terpenoid metabolic process), GO:0016114 (terpenoid biosynthetic process), GO:0150063 (visual system development), GO:0016101 (diterpenoid metabolic process), GO:0016102 (diterpenoid biosynthetic process), GO:0043010 (camera-type eye development), GO:0001754 (eye photoreceptor cell differentiation), GO:0001523 (retinoid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)