Protein: Serine/threonine-protein kinase receptor (A6HW56)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Single-pass type I membrane protein
InterPro domains:
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [328-340]
- IPR000472: Activin types I and II receptor domain (domain) [30-105]
- IPR001245: Serine-threonine/tyrosine-protein kinase, catalytic domain (domain) [204-489]
- IPR000719: Protein kinase domain (domain) [204-494]
- IPR003605: GS domain (domain) [174-204]
- IPR000333: Ser/Thr protein kinase, TGFB receptor (family) [25-498]
- IPR017441: Protein kinase, ATP binding site (binding_site) [210-231]
- IPR045860: Snake toxin-like superfamily (homologous_superfamily) [29-126]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [180-491]
Sequence:
MLLRSSGKLNVGTKKEDGESTAPTARPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEEDDSGTPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKDRDFVDGPIHHKALLISVTVCSLLLVLIILFCYFRYKRQEARPRYSIGLEQDETYIPPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNRTHFQSYIMADMYSFGLILWEIARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCMKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTLAKMSESQDIKL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0004888 (transmembrane signaling receptor activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0019199 (transmembrane receptor protein kinase activity), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity), GO:0004675 (transmembrane receptor protein serine/threonine kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0050793 (regulation of developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0044237 (cellular metabolic process), GO:0051240 (positive regulation of multicellular organismal process), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0044238 (primary metabolic process), GO:0051239 (regulation of multicellular organismal process), GO:0071704 (organic substance metabolic process), GO:0051094 (positive regulation of developmental process), GO:0048522 (positive regulation of cellular process), GO:0045597 (positive regulation of cell differentiation), GO:2000026 (regulation of multicellular organismal development), GO:1901564 (organonitrogen compound metabolic process), GO:0042127 (regulation of cell population proliferation), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0019538 (protein metabolic process), GO:0045595 (regulation of cell differentiation), GO:0051962 (positive regulation of nervous system development), GO:0043170 (macromolecule metabolic process), GO:0008284 (positive regulation of cell population proliferation), GO:0022008 (neurogenesis), GO:0007399 (nervous system development), GO:0060284 (regulation of cell development), GO:0010720 (positive regulation of cell development), GO:0060251 (regulation of glial cell proliferation), GO:0050769 (positive regulation of neurogenesis), GO:0051960 (regulation of nervous system development), GO:0060252 (positive regulation of glial cell proliferation), GO:0030182 (neuron differentiation), GO:0014015 (positive regulation of gliogenesis), GO:0050767 (regulation of neurogenesis), GO:0048699 (generation of neurons), GO:0014013 (regulation of gliogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0036477 (somatodendritic compartment), GO:0042995 (cell projection), GO:0044297 (cell body), GO:0097447 (dendritic tree), GO:0043025 (neuronal cell body), GO:0120025 (plasma membrane bounded cell projection), GO:0030425 (dendrite), GO:0043005 (neuron projection)