lokahq/bioreason-rl huggingface dataset:
Protein: Desmin isoform X1 (A0A8M9QFJ6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR050405: Intermediate filament structural protein (family) [3-461]
- IPR006821: Intermediate filament head, DNA-binding domain (domain) [9-107]
- IPR039008: Intermediate filament, rod domain (domain) [108-417]
- IPR018039: Intermediate filament protein, conserved site (conserved_site) [403-411]
Sequence:
MSHSYATSSSSSYRRMFGGPGYMTPPMSRGVFGRASTGGSGSSRVSSRVYEVSKSSTSSPGFSGYRASSYSMPNLSAGYTRSYGGMGETLDFSLADALNQEFLHTRTNEKAELQHLNDRFANYIEKVRMLEQQNQVLGVEVERLRGREPTRIADLYEDEMRELRREVEVVTNHRSRVEVERDNLADDLQKLKLRLQEEIALREEAENNLSAFRADVDAATLARLDLERRIETLQEEIAFLKKIHEEEIRELQAQMQETQVQIQMDMSKPDLTAALRDIRAQYEGIAAKNIAEAEDWYKSKVSDLNQAVSKNNEALKQSKLETMEYRHQIQSYTCEIDSLKGSNESLMRQMRDMEDRHGREAGALQDTIARLEAEIANMKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRIVMPMQSYSTISFRETSPEHQQRASEMHSKKTVLIKTIETRDGEE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0005488 (binding), GO:0005200 (structural constituent of cytoskeleton), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0003008 (system process), GO:0007610 (behavior), GO:0003012 (muscle system process), GO:0061061 (muscle structure development), GO:0048513 (animal organ development), GO:0007626 (locomotory behavior), GO:0007517 (muscle organ development), GO:0006936 (muscle contraction), GO:0060538 (skeletal muscle organ development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0030017 (sarcomere), GO:0031674 (I band), GO:0030018 (Z disc), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043292 (contractile fiber), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0030016 (myofibril), GO:0043232 (intracellular non-membrane-bounded organelle)
Protein: Synaptopodin 2-like protein isoform X2 (A0A8N7UVB2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR001478: PDZ domain (domain) [5-87]
- IPR036034: PDZ superfamily (homologous_superfamily) [2-101]
- IPR051976: Synaptopodin domain-containing protein (family) [1-1149]
Sequence:
MVAEEVIITLSGGAPWGFRLQGGIEHQKPLQVAKVRKRSKACRAGLREGDELMSINENSCGSLSHAQAMNLIDSMPGTLHIRVRRAMSPSSSRPHQSSVRQIHRGTLMSPTGRSGLTSPPGSEAYYGETDSDADVAAHERHRKPKRRSPSNSPGKAGRASPEGAETSEMSGYDSASDAQMYKLLGPNKREDTLPGVARREVIYQPPLHGAWSSQTSTETSSMSADDQNPREGLMEEDSGFQEPTNIPPLVSPERAKEALMLSSRSQLVPMVGPVDNPVDEELTLTYMDKAKQAKLNRGETITDKQVKEARSKCRTIASLLTDAPNPHSKGVLMFKKRRQRSKKYTLTSFGSVDEDMRQDSQEEDGIFPGSESEFDEEGFSAAPDPTWDSDYLEMLEKRCASRGQEGDGGALSPGLSDTSGKGAQLFEQQRKRAEEHARKIEAAQEQLQSQMLGISLKEAQALPPLQTAHPDPLTKLNVQPPPVAPKPARPSTTLYHDVQAAEAQNNKTQMNTPQTIPTVPVMVNGDASNTTVTAPSVMPKTNLSVLSTETVMPPPPTPLPELPASSVLNRTARPFAPGCITNRAATAPVVFRPAVSKKTPRPVSVAVVAPPFPAASEEHVMCVTPAIFGTQVTMSQMNANVSNEIIPTQPLAQGTSIPPPAAVSVESYSQSAFQCSPMESIQVASLPRVQAQKPTVPMIAETIVPPDDMVTSLATDMHPKGIAISSQTSSILTPTASETTSSPVIPLSPVVYREKPASVGGRTGILQDARRRSAYKPMFKMPDSKKNSPNPELLTMVQNLDDRPSHGYPEPDNIVYNIDENRTRVPPPVAPKPRVIPEMSQIPQAEGKGAELFARRQSRMDQFVVDTPYLQPATLQHQQSQSVIDLIQPRELSPTPSQWKYSPNVRAPPPIGYNPLLSPSCPVGVQRAGAKVSEGSAKGSKGSYGVPKEGIKALDFMRRQPYQLNPAMFSFGGGIGTQSSIPSYQRQQREGHTLTPPKQIPVKAARVYEIKRFSTPTPMSAPTLNPTVIIPRSQTTLGERISRSDMTSPPPEPVPETSLAPSRAPGLPELPKISSVPIPHPMPYSPPVPISSMSNLSYSGLQAAKQFKSAPELSALPPNPLKSPIQVPKPHFIATRAGVQPRVWRPGTLPH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0061061 (muscle structure development), GO:0048513 (animal organ development), GO:0009888 (tissue development), GO:0048731 (system development), GO:0007517 (muscle organ development), GO:0072359 (circulatory system development), GO:0007507 (heart development), GO:0060537 (muscle tissue development), GO:0007519 (skeletal muscle tissue development), GO:0060538 (skeletal muscle organ development), GO:0014706 (striated muscle tissue development), GO:0048738 (cardiac muscle tissue development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0030017 (sarcomere), GO:0031674 (I band), GO:0030018 (Z disc), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043292 (contractile fiber), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0030016 (myofibril), GO:0043232 (intracellular non-membrane-bounded organelle)
Protein: Metastasis-associated protein MTA3 isoform X2 (A0A8M9QE16)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR043151: Bromo adjacent homology (BAH) domain superfamily (homologous_superfamily) [2-145]
- IPR040138: Mesoderm induction early response protein/metastasis-associated protein (family) [1-590]
- IPR001005: SANT/Myb domain (domain) [267-316]
- IPR000949: ELM2 domain (domain) [148-259]
- IPR017884: SANT domain (domain) [266-318]
- IPR000679: Zinc finger, GATA-type (domain) [373-427]
- IPR001025: Bromo adjacent homology (BAH) domain (domain) [4-147]
- IPR035170: Metastasis-associated protein MTA1, R1 domain (domain) [463-541]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [269-321]
Sequence:
MAANMYRVGDYVFFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISQSLIQLADKHAKDLEEEKESPPESDLTEKQKHQLRHRELFLSRQYESLPATHIRGKCSVALLNETEVVLSYLEKEDTFFYSLVYDPTQKTLLADKGEIRVGPRFQADVPEMLQEGEADDRDQSKLEMKMWDPECPLTNKQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHRHGYDLSSALSVLVPQGGPVLCRDEMEEWSSSEANLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYNKPNPNQISVSNGKMATVNGAAAGTGSFHTAGGGRACESCFAVQSAQWYSWGPPNMQCRLCVSCWMYWKKYGGLKMPSRAEGAEEKTPPSPAPNESRSRGHCARQSSHMVPIRNSGSPKSSMKTKQAFLLQATRLTKLARHMCRDLIRLRRAARRPFVPINCGAIKAEYMIRVSEGMTGRPLKPKSSPRSTLTSVLQYLESRPATHVQRPHRTPGLQVQPPRRLLSSLPSHGPLGMLGKRSYHHHSRVESAERRAGATGQENPAHIVGPILHNGSSTGGSSLRGSGLMLRKRRPNWIDAPDDSFFLVSRETRKARRMLSRSQLRRACRQPCEQISLRRVPQGPSQVPILAPPHPSLRMRGPIVIHD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0005515 (protein binding), GO:0003712 (transcription coregulator activity), GO:0003714 (transcription corepressor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0048869 (cellular developmental process), GO:0007275 (multicellular organism development), GO:0048468 (cell development), GO:0009790 (embryo development), GO:0030154 (cell differentiation), GO:0048513 (animal organ development), GO:0030097 (hemopoiesis), GO:0048568 (embryonic organ development), GO:0035162 (embryonic hemopoiesis), GO:0060215 (primitive hemopoiesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Tumor necrosis factor receptor superfamily, member a precursor (A0A8M1P718)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR011029: Death-like domain superfamily (homologous_superfamily) [335-436]
- IPR034029: Tumour necrosis factor receptor 10A/B, death domain (domain) [349-433]
- IPR052491: Tumor necrosis factor receptor superfamily member 10 (family) [43-436]
- IPR001368: TNFR/NGFR cysteine-rich region (domain) [44-162]
- IPR000488: Death domain (domain) [352-427]
- IPR034024: Tumor necrosis factor receptor 10, N-terminal (domain) [56-163]
Sequence:
MDKSEAMKVCMALVIFSLALVGHGAAELGVSADHQNRTARQMTCLENHEYPHNGFCCKNCEAGTYVKEKCTSGQVMGKCSPCEKGTYAEHPTGMEQCLQCSQCHRDQTVVAECTSTSNTKCDCKIGTFCLPDEPCEVCKKCTKCKADEEEVSGCTPTSNTKCRRRPSHPTEGPTEKPSASNSTGTIFVIVSILILLVICAIVGAILFLKRRQRQQSETDGNLEEVKVPIDECPRSEEEQENSRNAGLEKEEEHRPESRPLLTQETQETGSKSIPVEDEDRGLGDSLPNTTSSSQTSLSALPQIIGDSPRSSPPAQRPTDRDQTESWPREDDPPRKLLPLLGEEESLSKSFDLFDSLDVRYHNKFFRSIGVSDNSIKLAETQQPMDKVYDLLRVWMQKEGLRANINTLLQALLDLDQRYSAEHIASKAVERGYYKYE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0010941 (regulation of cell death), GO:0010942 (positive regulation of cell death), GO:0043067 (regulation of programmed cell death), GO:0043068 (positive regulation of programmed cell death), GO:0043065 (positive regulation of apoptotic process), GO:0042981 (regulation of apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 isoform X3 (A0A8M2BDT5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR038043: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D 3, SWIB domain (domain) [288-361]
- IPR036885: SWIB/MDM2 domain superfamily (homologous_superfamily) [276-366]
- IPR019835: SWIB domain (domain) [282-361]
- IPR003121: SWIB/MDM2 domain (domain) [281-358]
Sequence:
MASEETAGGARKATKSKLFEFLVHGVRPGMPSGARMPHQGAPMGPPGPPYGGSPAVRPGLTNQSMEASRKRPNPSQQQIQQQAVQNRNRKKPVGFPGPNEMPGRQMDLRETQSDPTLGSNAKRRKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNAAKPDAEDSEGSIASWELRVEGKLLDDPGKMKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTGTTQETDGFQVKRPGDVNVRCTLLLMLDYQPPQFKLDPRLARLLGIHTQTRSSIIQALWQYVKTNKLQDSHDKEYINCDKYFQQIFDCPRLKFSEIPQRLTNLLLPPDPIVINHIISVDPNDQKKTACYDIDVEVEDPLKAQMSSFLLSTANQQEIASLDNKIHETIESINQLKIQRDFMLSFSRDPKGYIQDWLKSQSRDLKLMTDVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQRRQELEQALALRNT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0007389 (pattern specification process), GO:0009799 (specification of symmetry), GO:0061061 (muscle structure development), GO:0009887 (animal organ morphogenesis), GO:0009888 (tissue development), GO:0003002 (regionalization), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007507 (heart development), GO:0009855 (determination of bilateral symmetry), GO:0003007 (heart morphogenesis), GO:0042692 (muscle cell differentiation), GO:0060972 (left/right pattern formation), GO:0035051 (cardiocyte differentiation), GO:0072359 (circulatory system development), GO:0060537 (muscle tissue development), GO:0007368 (determination of left/right symmetry), GO:0055007 (cardiac muscle cell differentiation), GO:0051146 (striated muscle cell differentiation), GO:0014706 (striated muscle tissue development), GO:0048738 (cardiac muscle tissue development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Actin filament-associated protein 1-like 2 isoform X2 (A0A8M9QJ86)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR030113: Actin-filament associated protein (family) [1-885]
- IPR001849: Pleckstrin homology domain (domain) [205-471]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [182-473]
Sequence:
MDKHKVLEQLLEQLQKFLKILDVEKLSGNAKVQKGLLMELLQSYKSSNGGDEEYIYMNKVIVTCQTQDKTNRDHRPEANGDPSKHISVKNPPEPPPPRPCNTGREPFPLPPAPAPASMENESYYEDPQPYDPISINDFGCFAVITGLRKRVEASNGVVYAVITREDTEQLSSSYESYDEEEVTKGKSTAQHQWPSPEASIELMKDARICAFLWRKKWLGQWAKQLCVVREHRLLCYKSSKDQTPLLDISLLGCSVVYKEKQTKRKEHKLKISPLGAEAIVLGLQSKEQAEQWLKVIQEISPKNTTGSDVTDSPTLICTKGEQSERYSVASESGSSTDSHAENMENKDVKKKYGKFSNLMNIGKKKVCSLESPEKSVDTSGYLNVLVNTQWRSRWCSVKDRQLWIYSDKSKGKVAQQPLSLEGCMVLPDPSPEHLYSFRIQMDGEELAILEAKSSADMGHWLGLILSQTGTKTDPEDLSYDYVNSERISSIVNAAKTSMYLMQRRYSEPNTYTDSPPSDPQTCDDIYDDVPSTENEQEEVQEVQNGSEEGTVNAEEENGKDRVYLDLIPLRSFLHTSSGRVSPQTSSTTQTEISPSTTPHVDDQLKEPVYESSLPTSTENEVPPPVAPRVDTDPSPVPNLHVQPQKISFLGQEIQKKASPLPKTQSLPQTSAQTPQSPPTSRARAASTDRLLDRLKFSPAAGPGSVEVKLGKNRTEADVRRYTDDRDRLEREREEVKNTLATLRKDRREVKDELSSCQDPIRQASLEARLKQMEETCREAERRRVEVELSLMEVKENLRKVESGPFTLGTTVDSSLLDISVPKPAAVSSPAPNTPNNTNINTPACTNNEDSPVNSATALKNRPPSVMAASKGNVLQKAKEWEKKNTT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019904 (protein domain specific binding), GO:0017124 (SH3 domain binding), GO:0042169 (SH2 domain binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0060900 (embryonic camera-type eye formation), GO:0009887 (animal organ morphogenesis), GO:0048729 (tissue morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0009888 (tissue development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009790 (embryo development), GO:0048568 (embryonic organ development), GO:0048562 (embryonic organ morphogenesis), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0090596 (sensory organ morphogenesis), GO:0002072 (optic cup morphogenesis involved in camera-type eye development), GO:0002009 (morphogenesis of an epithelium), GO:0060429 (epithelium development), GO:0016331 (morphogenesis of embryonic epithelium), GO:0002011 (morphogenesis of an epithelial sheet), GO:0048592 (eye morphogenesis), GO:0001654 (eye development), GO:0048048 (embryonic eye morphogenesis), GO:0031076 (embryonic camera-type eye development), GO:0061386 (closure of optic fissure), GO:0150063 (visual system development), GO:0043010 (camera-type eye development), GO:0048593 (camera-type eye morphogenesis), GO:0048596 (embryonic camera-type eye morphogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Catenin delta-2 isoform X7 (A0A8M3APS9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR000225: Armadillo (repeat) [516-964]
- IPR028435: Plakophilin/Delta catenin (family) [48-1000]
- IPR011989: Armadillo-like helical (homologous_superfamily) [486-983]
- IPR016024: Armadillo-type fold (homologous_superfamily) [486-969]
Sequence:
MPVPDQPSGTENSSMLSPVLNASNGDGSETETTSAILASVKEQELQFERLTRELEAERQIVATQLERCKLGSETGSMSSISSADEKFRWNNQDGQKDIEEELTTGLELVDSCIRSLQESGILDSQEFTAGERPGILSQSALQLNNQEGTFPYPVSYHSNQTLALGDLSASQPPRSGQVGGALHSYNQALGSPSKLQRLGSASDMPSYATLARVSSPKQSPSRLAKSYSTSSPINMAAGGGSSSSPLHMAGAGNVSNSSPLHQLSAAVGSYATLSPTKRMLHTTDQYKISHDLYANATLQRPGSLAGSRGSYSSQHSHLGSELRPLQSPEHHIDPIYEDRVYQKAPLRNFNQAQDPMNQFCDQVLNFLLCPYSPVIAPSSPGVDSIPLQRTGSQNATGTFPRAGYATGPGASTADYANPYRTLQFCPSTDSPYSKSGPALPPEATLVRSPSVDSIQKDPRYDPEFLVWNQNQAEQRMTKEFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKSEIRRQGGIQLLVDLLDHRMTDVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDVEIRELLTGVLWNLSSCDALKMPIIQDALAVLTNTVIIPHSGWDTSPLQDDRKLHLHSSQVLRNATGCLRNVSSAGEEARRRMRECEGLTDALLYVIQTALGTSEIDSKTIENCVCILRNLSYRLAAETSQGQQMGSEELDGVLCTDASGKDAESSGCWGKKKKKKKSHDQWDGVGPFPDSSDPPKGLQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKVGPTLKPWSVYIRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNNNSTGTGGSSKSMSDDTITAICCALHEVITKNMENTKALRDAGGIEKLIGIARSKGDKHTPKVVKAASQVLNSMWQYRDLRSLYKKDGYSQYHFVGSSSTIERDRQRPYSSSRTPSISPVRTSPNNRSASAPTSPREMMSLKERKTDYESTGSNSTYHGNKGEHTSRKDAMAAQISSGTSTLFRGAYMSPADDIKHNQVSAQGNPPEAYPPFQTPPGANFEEPYYEDQAHKRPPPAADGTMHLGLKSTGNYVDFYSASRPYSELNYETSHYPASPDSWV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048870 (cell motility), GO:0030154 (cell differentiation), GO:0016477 (cell migration), GO:0048731 (system development), GO:0001764 (neuron migration), GO:0022008 (neurogenesis), GO:0007399 (nervous system development), GO:0048699 (generation of neurons)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction), GO:0070161 (anchoring junction), GO:0005911 (cell-cell junction), GO:0005912 (adherens junction)
Protein: Tumor necrosis factor ligand superfamily member 13B isoform X2 (A0A8M6Z8G0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted
InterPro domains:
- IPR008983: Tumour necrosis factor-like domain superfamily (homologous_superfamily) [110-262]
- IPR006052: Tumour necrosis factor domain (domain) [119-262]
- IPR051748: Tumor Necrosis Factor Ligand Superfamily (family) [10-262]
Sequence:
MPAEDVGPGRGERRRLSWLFLVLVAAAITSSSLSVISLYHVLALKAEVEGLRAEVARKREEQSGMLDEPVNDAEKQTHREEGGDSVEYLHQADMDITTDPSVMSKRSLSHVPKKAEPQPCLQMMADNKKKTFQKEFAFDYCTAIPWQVGLKRGSALEEEQGTILVKEEGFFFIYSQVYYTDPTFAMGHIVIRIKKNVVGNESQHVVLFRCIQSMNRVNHYNTCYTGGVVKLDSGDKLDLLIPRANANISLEGDATFLGAIKLA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0005126 (cytokine receptor binding), GO:0032813 (tumor necrosis factor receptor superfamily binding)
Biological Process (BP): GO:0008150 (biological process), GO:0002376 (immune system process), GO:0032501 (multicellular organismal process), GO:0042592 (homeostatic process), GO:0001776 (leukocyte homeostasis), GO:0048871 (multicellular organismal-level homeostasis), GO:0002260 (lymphocyte homeostasis), GO:0048872 (homeostasis of number of cells), GO:0001782 (B cell homeostasis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098552 (side of membrane), GO:0009986 (cell surface), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0009897 (external side of plasma membrane), GO:0005886 (plasma membrane)
Protein: Cytospin-A (A0A8M9PD49)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration
Subcellular location: Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton. Cell junction, gap junction
InterPro domains:
- IPR001715: Calponin homology domain (domain) [1040-1145]
- IPR050540: F-actin Monooxygenase Mical (family) [408-1145]
- IPR036872: CH domain superfamily (homologous_superfamily) [1039-1146]
Sequence:
MCSPRKITSAGVRLRCKCIKNLEPSMKKATKPTAATSRTSVGTKAPGRSEGSSNMGTGGKMTNKTQSSAPLSKAKSSDDLPAVSAGSGSVSASNSNTTARNKRGSSSQITSNTETRSKTTSGLSGRRATSTVSKEPGLTRDNLRERSRTSVAKKPTDTMPQKRSRCRTLPDSESKMSKSRSDSQISHKAVLECQVNDLLGLAKSKDLEILHLRSELRGMRTQLGLEELEAPNQEQVSQETMQPPEKEVISATDVESTLLLLQDQNQGILDELNMLKSENRMLKDRLNALGFSLEQRLDSPEKSLRCLPMSPEHVVGGDSSSGGHSESVRGGMRASSAEGSAQGSTEDLLSEQRHLGSPDAVDSECSEAYQPITSSDDALDAPSGCGSSSESEGGLPSREHSRRGSSGNTSEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELSTENERLGEERAILVDSLCQQGERLELYGRQLEYFRGLLDEHCVAYVKDDEDAKSGRYVELERRYAELNEGSRFEREQLLGVQQQLSSALKMAEHENAEAQGLMAALKERVIMAERAVEIERRERAVAKAELEALRVLSEGEQVELNRCRIQLEQERQRVAQLLSIHNAGDKTDIRHLLESERLDKERAEAKAAQLKEELGHTRSEAAQLQEAISKLEDEFRAFRDDVQSQLAEQKRLLEQQCSELEEKDTEIADMKETIFELEDEVEQHRAVKLHDNLIISDLENSIKKLHDQKYDMEKEIKVLHRKLREESAEWRQFQADLQTAVIIANDIKTEAQEEIGDLRRRLQEAQEKNEKMNKELEELKSRKQDEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPSPTVKTLIKSFDSASQGPVQGSPTAAAAAVAAATAISRTPLSPSPVKTPPAAAVSPIQRHTISSKPLSSMLDKRPSFNDLNIPAEHLLRTSPVTRPGCPIQRVTNMDTSKAISVSRRSSEELKRDLLAPESSAPSSLMSSPQLSLSSNASSPTASITPTTRGRLREERKDPLSALAREYGGSKRNALLRWCQKKTEGYQNIDITNFSSSWNDGLAFCAILHTYLPAHIPYHELNSLDKRRNFTLAFQAAESVGIKSTLDIGEMVHTERPDWQSVMTYVTSIYKYFET
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009887 (animal organ morphogenesis), GO:1904888 (cranial skeletal system development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0097094 (craniofacial suture morphogenesis), GO:0060349 (bone morphogenesis), GO:0048705 (skeletal system morphogenesis), GO:0060348 (bone development), GO:0001501 (skeletal system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0005813 (centrosome), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015630 (microtubule cytoskeleton)