Protein: Protein kinase, cGMP-dependent, type 1 (Mapped), isoform CRA_a (A6I0Z2)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR000961: AGC-kinase, C-terminal (domain) [20-71]
Sequence:
MQSSLLDSTLGSKLNGRWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDSDEPPPDDNSGWDIDF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0019899 (enzyme binding), GO:0019900 (kinase binding), GO:0019901 (protein kinase binding), GO:0051019 (mitogen-activated protein kinase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0008152 (metabolic process), GO:0040007 (growth), GO:0048519 (negative regulation of biological process), GO:0009605 (response to external stimulus), GO:0048589 (developmental growth), GO:0048856 (anatomical structure development), GO:0023057 (negative regulation of signaling), GO:0009653 (anatomical structure morphogenesis), GO:0042221 (response to chemical), GO:0051240 (positive regulation of multicellular organismal process), GO:0006807 (nitrogen compound metabolic process), GO:0051241 (negative regulation of multicellular organismal process), GO:0071840 (cellular component organization or biogenesis), GO:0051239 (regulation of multicellular organismal process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0009892 (negative regulation of metabolic process), GO:0065008 (regulation of biological quality), GO:0050793 (regulation of developmental process), GO:0016049 (cell growth), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0007568 (aging), GO:0051093 (negative regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0009628 (response to abiotic stimulus), GO:0007275 (multicellular organism development), GO:0009058 (biosynthetic process), GO:0051051 (negative regulation of transport), GO:0019222 (regulation of metabolic process), GO:0032879 (regulation of localization), GO:0071704 (organic substance metabolic process), GO:0003008 (system process), GO:0044237 (cellular metabolic process), GO:0009893 (positive regulation of metabolic process), GO:0065009 (regulation of molecular function), GO:0006950 (response to stress), GO:0051094 (positive regulation of developmental process), GO:0048585 (negative regulation of response to stimulus), GO:0044238 (primary metabolic process), GO:0007610 (behavior), GO:0048522 (positive regulation of cellular process), GO:0001666 (response to hypoxia), GO:0009968 (negative regulation of signal transduction), GO:0001666 (response to hypoxia), GO:0010942 (positive regulation of cell death), GO:0051129 (negative regulation of cellular component organization), GO:0060548 (negative regulation of cell death), GO:0060560 (developmental growth involved in morphogenesis), GO:0009314 (response to radiation), GO:0048731 (system development), GO:0070482 (response to oxygen levels), GO:0044057 (regulation of system process), GO:0048513 (animal organ development), GO:0009966 (regulation of signal transduction), GO:0060255 (regulation of macromolecule metabolic process), GO:0008217 (regulation of blood pressure), GO:0006725 (cellular aromatic compound metabolic process), GO:0051098 (regulation of binding), GO:0009725 (response to hormone), GO:0034763 (negative regulation of transmembrane transport), GO:0035295 (tube development), GO:0009894 (regulation of catabolic process), GO:0099536 (synaptic signaling), GO:1901360 (organic cyclic compound metabolic process), GO:0032410 (negative regulation of transporter activity), GO:0007611 (learning or memory), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0045595 (regulation of cell differentiation), GO:0016043 (cellular component organization), GO:0007162 (negative regulation of cell adhesion), GO:0032410 (negative regulation of transporter activity), GO:0007611 (learning or memory), GO:0002026 (regulation of the force of heart contraction), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0051897 (positive regulation of protein kinase B signaling), GO:0051128 (regulation of cellular component organization), GO:0051962 (positive regulation of nervous system development), GO:0090066 (regulation of anatomical structure size), GO:1903531 (negative regulation of secretion by cell), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0046888 (negative regulation of hormone secretion), GO:0021675 (nerve development), GO:0050773 (regulation of dendrite development), GO:0010648 (negative regulation of cell communication), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:1903530 (regulation of secretion by cell), GO:0051049 (regulation of transport), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0001568 (blood vessel development), GO:0046483 (heterocycle metabolic process), GO:0044092 (negative regulation of molecular function), GO:0060341 (regulation of cellular localization), GO:0008285 (negative regulation of cell population proliferation), GO:0051224 (negative regulation of protein transport), GO:0034762 (regulation of transmembrane transport), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0010817 (regulation of hormone levels), GO:0031324 (negative regulation of cellular metabolic process), GO:0043170 (macromolecule metabolic process), GO:0010033 (response to organic substance), GO:0009991 (response to extracellular stimulus), GO:2000026 (regulation of multicellular organismal development), GO:0042127 (regulation of cell population proliferation), GO:0010941 (regulation of cell death), GO:0009888 (tissue development), GO:1901698 (response to nitrogen compound), GO:0006139 (nucleobase-containing compound metabolic process), GO:0010646 (regulation of cell communication), GO:0031325 (positive regulation of cellular metabolic process), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0045596 (negative regulation of cell differentiation), GO:0043271 (negative regulation of monoatomic ion transport), GO:0031323 (regulation of cellular metabolic process), GO:0050877 (nervous system process), GO:0099177 (regulation of trans-synaptic signaling), GO:0080090 (regulation of primary metabolic process), GO:0009612 (response to mechanical stimulus), GO:0009896 (positive regulation of catabolic process), GO:0032102 (negative regulation of response to external stimulus), GO:0035239 (tube morphogenesis), GO:1901652 (response to peptide), GO:2000272 (negative regulation of signaling receptor activity), GO:0009059 (macromolecule biosynthetic process), GO:0030030 (cell projection organization), GO:0071453 (cellular response to oxygen levels), GO:0008015 (blood circulation), GO:0051246 (regulation of protein metabolic process), GO:0043069 (negative regulation of programmed cell death), GO:0043067 (regulation of programmed cell death), GO:0001944 (vasculature development), GO:0070201 (regulation of establishment of protein localization), GO:0030705 (cytoskeleton-dependent intracellular transport), GO:0048545 (response to steroid hormone), GO:0060251 (regulation of glial cell proliferation), GO:0050769 (positive regulation of neurogenesis), GO:0090257 (regulation of muscle system process), GO:0090278 (negative regulation of peptide hormone secretion), GO:0010468 (regulation of gene expression), GO:0048666 (neuron development), GO:2000177 (regulation of neural precursor cell proliferation), GO:0032413 (negative regulation of ion transmembrane transporter activity), GO:0051223 (regulation of protein transport), GO:0050768 (negative regulation of neurogenesis), GO:0051223 (regulation of protein transport), GO:0034766 (negative regulation of monoatomic ion transmembrane transport), GO:0007399 (nervous system development), GO:0090304 (nucleic acid metabolic process), GO:0031667 (response to nutrient levels), GO:0072359 (circulatory system development), GO:0036293 (response to decreased oxygen levels), GO:0010563 (negative regulation of phosphorus metabolic process), GO:0015980 (energy derivation by oxidation of organic compounds), GO:0090317 (negative regulation of intracellular protein transport), GO:1904950 (negative regulation of establishment of protein localization), GO:1901701 (cellular response to oxygen-containing compound), GO:0010467 (gene expression), GO:0032386 (regulation of intracellular transport), GO:0071456 (cellular response to hypoxia), GO:0071417 (cellular response to organonitrogen compound), GO:0050890 (cognition), GO:0009416 (response to light stimulus), GO:0043086 (negative regulation of catalytic activity), GO:1901215 (negative regulation of neuron death), GO:0010562 (positive regulation of phosphorus metabolic process), GO:0031344 (regulation of cell projection organization), GO:0071310 (cellular response to organic substance), GO:0043068 (positive regulation of programmed cell death), GO:0034765 (regulation of monoatomic ion transmembrane transport), GO:0060284 (regulation of cell development), GO:0051248 (negative regulation of protein metabolic process), GO:0010720 (positive regulation of cell development), GO:0050804 (modulation of chemical synaptic transmission), GO:1901699 (cellular response to nitrogen compound), GO:1901214 (regulation of neuron death), GO:0002792 (negative regulation of peptide secretion), GO:0046903 (secretion), GO:0032880 (regulation of protein localization), GO:0051960 (regulation of nervous system development), GO:0010766 (negative regulation of sodium ion transport), GO:0043267 (negative regulation of potassium ion transport), GO:0007600 (sensory perception), GO:0030855 (epithelial cell differentiation), GO:0007613 (memory), GO:0043434 (response to peptide hormone)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0031974 (membrane-enclosed lumen), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0012505 (endomembrane system), GO:0005654 (nucleoplasm), GO:0005794 (Golgi apparatus), GO:0043233 (organelle lumen), GO:0030141 (secretory granule), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0042383 (sarcolemma), GO:0001669 (acrosomal vesicle), GO:0031982 (vesicle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0097708 (intracellular vesicle), GO:0005634 (nucleus)