lokahq/bioreason-rl huggingface dataset:
Protein: Synaptophysin-like protein, isoform CRA_d (A6HB74)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
- IPR008253: Marvel domain (domain) [10-156]
- IPR001285: Synaptophysin/synaptoporin (family) [2-134]
Sequence:
MSTFQINLNPLKEPLGFIKILEWFASIFAFATCGGFKGKTEIQVNCLSAPGENKTITATFGYPFRLNQASFHSAPNVNVCKVNWEKHVLIGDYSSSAQFYVTFAVLVFLYCIAALLLYVGYTNLYRDSRKLPMIIFGFLNMILWGGNAWFVYKETSLHSPSNTSASHGQGGVPPTSGM
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0019904 (protein domain specific binding), GO:0000149 (SNARE binding), GO:0019905 (syntaxin binding), GO:0017075 (syntaxin-1 binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0023051 (regulation of signaling), GO:0050794 (regulation of cellular process), GO:0010646 (regulation of cell communication), GO:0099177 (regulation of trans-synaptic signaling), GO:0050804 (modulation of chemical synaptic transmission)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0016020 (membrane), GO:0098793 (presynapse), GO:0030054 (cell junction), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0008021 (synaptic vesicle), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0030133 (transport vesicle), GO:0043227 (membrane-bounded organelle), GO:0030658 (transport vesicle membrane), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0012506 (vesicle membrane), GO:0070382 (exocytic vesicle), GO:0030672 (synaptic vesicle membrane), GO:0098984 (neuron to neuron synapse), GO:0031982 (vesicle), GO:0030659 (cytoplasmic vesicle membrane), GO:0097708 (intracellular vesicle), GO:0099501 (exocytic vesicle membrane), GO:0098686 (hippocampal mossy fiber to CA3 synapse)
Protein: CDK-activating kinase assembly factor MAT1 (Q6AZ68)
Organism: Rattus norvegicus (Rat)
Function: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex
Subcellular location: Nucleus
InterPro domains:
- IPR057657: MAT1, C-terminal CAK anchor (domain) [255-305]
- IPR017907: Zinc finger, RING-type, conserved site (conserved_site) [26-35]
- IPR003903: Ubiquitin interacting motif (conserved_site) [142-161]
- IPR015877: MAT1, centre (domain) [53-250]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [1-65]
- IPR004575: Cdk-activating kinase assembly factor MAT1/Tfb3 (family) [1-308]
- IPR001841: Zinc finger, RING-type (domain) [3-50]
Sequence:
MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLENTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQESEQRRLFIQKEEELQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKSMKPVTFSTGIKMGQQISLAPIQKLEEALYEYQPLQIETCGPQVPEQELLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0007049 (cell cycle), GO:0048523 (negative regulation of cellular process), GO:0022402 (cell cycle process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0044770 (cell cycle phase transition), GO:1903047 (mitotic cell cycle process), GO:0042127 (regulation of cell population proliferation), GO:0060548 (negative regulation of cell death), GO:0010941 (regulation of cell death), GO:0000278 (mitotic cell cycle), GO:0008284 (positive regulation of cell population proliferation), GO:0048660 (regulation of smooth muscle cell proliferation), GO:0048661 (positive regulation of smooth muscle cell proliferation), GO:0044772 (mitotic cell cycle phase transition), GO:0044843 (cell cycle G1/S phase transition), GO:0043069 (negative regulation of programmed cell death), GO:0043067 (regulation of programmed cell death), GO:0043066 (negative regulation of apoptotic process), GO:0042981 (regulation of apoptotic process), GO:0000082 (G1/S transition of mitotic cell cycle)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Protein kinase, AMP-activated, gamma 3 non-catatlytic subunit (Predicted) (A6JVW1)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR046342: CBS domain superfamily (homologous_superfamily) [172-485]
- IPR050511: AMP-activated protein kinase gamma/SDS23 families (family) [176-481]
- IPR000644: CBS domain (domain) [197-490]
Sequence:
MEPELEHTLPGTLTWSHSGGPESQEMDFLEPEENSWPSPTVATSSERTCAIRGVKASRWTRQEAVEEAEPPGLGEGAQSGPAAESTRQKATFPKATPLAQAVPLADAETSTTGWDLFLPDCAASAVGSSTGDLELTIEFPGPEVWDCELKGLEQDRPRPCPSPQAPLLSLSWDDELQKPGAQIYMHFMQEHTCYDAMATSSKLVIFDTTLEIKKAFFAMVANGVRAAPLWDSKKQSFVGMLTITDFILVLHRYYRSPLVQIYEIEEHKIETWRGFSAEIYLQGCFKPLVSISPNDSLFEAVYALIKNRIHRLPVLDPVSGTVLYILTHKRLLKFLHIFGALLPRPSFLCRTIQDLGIGTFRDLAVVLETAPILTALDIFVDRRVSALPVVNESGQVVGLYSRFDVIHLAAQQTYNHLDMSVGEALRQRTLCLEGVLSCQPHESLGEVIDRIAREQVHRLVLVDETQHLLGVVSLSDILQALVLSPAGIDALSA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity), GO:0004679 (AMP-activated protein kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0065009 (regulation of molecular function), GO:0050790 (regulation of catalytic activity)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0140535 (intracellular protein-containing complex), GO:0031588 (nucleotide-activated protein kinase complex), GO:1990234 (transferase complex), GO:0061695 (transferase complex, transferring phosphorus-containing groups), GO:1902911 (protein kinase complex)
Protein: S100 calcium-binding protein, ventral prostate, isoform CRA_b (A6KMS0)
Organism: Rattus norvegicus (Rat)
InterPro domains:
Sequence:
MAQNLTSTEQEIMELLMILQEFSVKKIDKLDAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0005509 (calcium ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042592 (homeostatic process), GO:0048878 (chemical homeostasis), GO:0019725 (cellular homeostasis), GO:0042221 (response to chemical), GO:0050801 (monoatomic ion homeostasis), GO:0055082 (intracellular chemical homeostasis), GO:1901700 (response to oxygen-containing compound), GO:0098771 (inorganic ion homeostasis), GO:0010033 (response to organic substance), GO:0014070 (response to organic cyclic compound), GO:0055080 (monoatomic cation homeostasis), GO:1901654 (response to ketone), GO:0006873 (intracellular monoatomic ion homeostasis), GO:0033993 (response to lipid), GO:0055074 (calcium ion homeostasis), GO:0006874 (intracellular calcium ion homeostasis), GO:0033574 (response to testosterone), GO:0030003 (intracellular monoatomic cation homeostasis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Lamimin, gamma 2 (A6ICU7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane
InterPro domains:
- IPR056863: Laminin/attractin/netrin-like, EGF domain (domain) [28-75]
- IPR002049: Laminin-type EGF domain (domain) [28-614]
- IPR000742: EGF-like domain (domain) [36-603]
- IPR000034: Laminin IV (domain) [213-381]
- IPR050440: Laminin/Netrin Extracellular Matrix (family) [28-904]
Sequence:
MPALWLSCCLGVALLLPAAQATSRREVCDCNGKSRQCVFDQELHRQTGNGFRCLNCNDNTAGVHCERCREGFYRQRDRDRCLPCNCHSKGSLGAGCDNSGQCRCKPGVVGQRCDRCQPGFHMLTDAGCTRDQRQLDSKCDCDPAGISGPCDSGRCVCKPAVTGERCDRCRAGYYHLDRANPEGCTQCFCYGHSDSCHTSADFSVHKITSTFNQDEDGWKAVQRNWAPAKLHWSPRHQDVFSSARRSDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAYDVILEGAGLQIRAPLMPPGKTLPCGITKTYTFRLNEHPSSHWSPQLSYFEYRRLLRNLTALLIRATYGEYSTGYIDNVTLISARPVSGAPAPWVERCVCPAGYKGQFCQECASGYKRDSARLGPFGTCVPCNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGFFGDPFGERGPVRPCQRCQCNNNVDPSASGNCDQLTGRCLKCIYNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPVGSEPGECRSDGSCVCKPGFGGLNCAHAAALTSCPACYNQVKTQMDQFAQQLQNLEALVSKAQGGNGAVPSEELEGRMQQAEQALRDILREAQISEGAMRALSLQLAKARSQENNYKNRLDDLKMTVERIRALGSQYQNRVQDTSRLISQMRLSLAESEASLQNTNIHSSEHYVGPNGFKSLAQEAARLADSHVESANTMKQLTRETEDYSKQALSLARKALSGGGGSGVLDSSVVQGLMGKLEKTKSLTQQLSREGTQADIEADRSYQHSLRLLDSASQLQGIRDSSFQAEAKRIRQKADSLSNLVTKQMDAFTSVRNNLGNWEKETRQLLQTGKDRRQVDFGSAAFPCQPC
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:1901681 (sulfur compound binding), GO:0097367 (carbohydrate derivative binding), GO:0005515 (protein binding), GO:0008201 (heparin binding), GO:0005539 (glycosaminoglycan binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009887 (animal organ morphogenesis), GO:0009888 (tissue development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007507 (heart development), GO:0060485 (mesenchyme development), GO:0003007 (heart morphogenesis), GO:0048762 (mesenchymal cell differentiation), GO:0072359 (circulatory system development), GO:0060317 (cardiac epithelial to mesenchymal transition), GO:0001837 (epithelial to mesenchymal transition)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0016020 (membrane), GO:0005615 (extracellular space), GO:0043256 (laminin complex), GO:0048471 (perinuclear region of cytoplasm), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0030312 (external encapsulating structure), GO:0005576 (extracellular region), GO:0031012 (extracellular matrix), GO:0005938 (cell cortex), GO:0062023 (collagen-containing extracellular matrix), GO:0005604 (basement membrane)
Protein: ADP-ribosylation factor-like 12 (Predicted) (A6HIP0)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR031152: Plexin domain-containing protein (family) [1-497]
- IPR002165: Plexin repeat (repeat) [304-348]
Sequence:
MRAQLWLLQLLLLCGTARALSPATPAGHDERQGSAWTAKRTRQGWNRRVRESPGQVLKPGKTQLSQDLGGDSLAIDTLPDNRTRVVEDNHNYYVSRVYGPGEQRTRDLWVDLSVANRNHVKVHRILSSSHRQASRVVLSFDFPFYGHPLRQITIATGGFIFMGDVLHRMLTATQYVAPLMANFNPGYSDNSTVAYFDNGTVFVVQWDHVYLQGREDRGSFTFQAALHQDGRIVFGYKEIPMAVLDISSAQHPVKAGLSDAFMILNSSPEVPESRRRTIFEYHRVELDSSKITTTSAVEFTPLPTCLQHQSCDACMSSNLTFNCSWCYVLQRCSSGFDRYRQEWLTYGCAQEAEGKTCEHFQDEGHYSASPDSSFSPSDGGSTTSSSLFIDSLTTEDDTKLNPYAEGDGLPDNSSPKTKGPPVHLGTIVGIVLAVLLVAAIILAGIYISGHPNSNAALFFIERRPHHWPAMKFHNHPNHSTYTEVEPSGHEKEGFVEAEQC
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0021510 (spinal cord development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0036477 (somatodendritic compartment), GO:0042995 (cell projection), GO:0044297 (cell body), GO:0097447 (dendritic tree), GO:0043025 (neuronal cell body), GO:0120025 (plasma membrane bounded cell projection), GO:0030425 (dendrite), GO:0043005 (neuron projection)
Protein: Angiopoietin-like 3, isoform CRA_b (A6JRL4)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR036056: Fibrinogen-like, C-terminal (homologous_superfamily) [240-453]
- IPR002181: Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain (domain) [237-455]
- IPR014716: Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 (homologous_superfamily) [235-454]
- IPR050373: Fibrinogen C-terminal domain-containing protein (family) [185-454]
Sequence:
MHTIKLLLFVVPLVISSRVDPDLSPFDSVPSEPKSRFAMLDDVKILANGLLQLGHGLKDFVHKTKGQINDIFQKLNIFDQCFYDLSLQTNEIKEEEKELRRTTSKLQVKNEEVKNMSLELNSKLESLLEEKMALQHRVRALEEQLTSLVQNPPGAREHPEVTSLKSFVEQQDNSIRELLQSVEEQYKQLSQQHIQIKEIENQLRKTGIQEPTENSLYSKPRAPRTTPPLHLKEAKNIEQDDLPADCSAIYNRGEHTSGVYTIRPSSSQVFNVYCDTQSGTPRTLIQHRKDGSQNFNQTWENYEKGFGRLDGEFWLGLEKIYAIVKQSNYILRLELQDWKDSKHYAEYSFHLGNHETNYTLHVAEIAANIPEALPEHRDLMFSTWDHRAKGQLYCPESYSGGWWFSDMCGENNLNGKYNKPRAKSKPERRRGISWRPRGGKLYSIKSSKMMLQPTT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030234 (enzyme regulator activity), GO:0005515 (protein binding), GO:0140678 (molecular function inhibitor activity), GO:0042802 (identical protein binding), GO:0004857 (enzyme inhibitor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009719 (response to endogenous stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:0009725 (response to hormone)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0009986 (cell surface), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0005769 (early endosome), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)
Protein: Mothers against decapentaplegic homolog (A6J5A7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm. Nucleus
InterPro domains:
- IPR008984: SMAD/FHA domain superfamily (homologous_superfamily) [320-453]
- IPR001132: SMAD domain, Dwarfin-type (domain) [330-458]
- IPR036578: SMAD MH1 domain superfamily (homologous_superfamily) [162-276]
- IPR013790: Dwarfin (family) [274-452]
- IPR003619: MAD homology 1, Dwarfin-type (domain) [168-274]
- IPR017855: SMAD-like domain superfamily (homologous_superfamily) [325-456]
- IPR013019: MAD homology, MH1 (domain) [149-276]
Sequence:
MFRSKRSGLVRRLWRSRVVPDREEGSGGGCGGDEDGSLGSRAEPAPRAREGGGCGRSEVRSVAPRRLRDAVGPRGALIAGRRRRTGGPPRPVSEPGAGAGGSPLDVVEPGGPGWLPESDCETVTCCLFSERDAAGAPRDSGDPQARQSPEPEEGGGPRSREARSRLLLLEQELKTVTYSLLKRLKERSLDTLLEAVESRGGVPGGCVLVPRADLRLGGQPAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPPDQHKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDFERSGLLQHADAAHGPL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0044389 (ubiquitin-like protein ligase binding), GO:0031625 (ubiquitin protein ligase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009719 (response to endogenous stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0043627 (response to estrogen)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0005769 (early endosome), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle), GO:0005634 (nucleus)
Protein: RCG59972 (A6HSJ2)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR003961: Fibronectin type III (domain) [136-440]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [29-439]
- IPR048668: Cytokine receptor common subunit beta, N-terminal (domain) [32-119]
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [29-439]
- IPR015152: Growth hormone/erythropoietin receptor, ligand binding (domain) [246-333]
- IPR003531: Short hematopoietin receptor, family 1, conserved site (conserved_site) [405-436]
- IPR015373: Interferon/interleukin receptor domain (domain) [342-431]
- IPR011365: Cytokine IL-3/IL-5/GM-CSF receptor common beta chain (family) [5-896]
Sequence:
MDQHMAFIWGLCYMALVALCWRHGVTKAEETVPLKTLQCYNDYIERIICSWADTEDAQGLVNLTLYHWLDKKQPMSCELSEDLMWSECPSSHRCVPRRCVLPYTQFSVSKEDYYSLQPDRDLSIHLVVPLAQHVQPPPPKDISISPSGDHFLLKWSVPHGDAQVSLLSQKDIQFEVAYKRLQDSWEDASSLHTSNLWVTLEPKLFLPNSIYVARVRTQLAPGSSLSGRPSRWSPEVHWDSPTGDKARPQNLQCFFDGIQSLNCSWEVWTKVTDSVSFGLFYSSSPKAGEKKCSPVVKELQASRYTRYHCSLNVSDPAAHSQYTVSVKRLEQGKFIESFNHIQMNPPTLNLTKNRDSYSLHWETQKMSYPFIQHAFQVQYKKKLDSWEDSKTENLNHAHSMDLPQLEPGTSYCARVRVKTIPEYKGLWSEWSNECTWTTDWVMPTLWIVLILVFLILTFLLALRFGCIYGCKLYRKWKEKIPNPSKSLLFQDGGKGLWPPGSTVTFSSKNPTPQGPQSNLFSELQGVSYTHLEDNEVSPLTIEDPNIIRDPSSGPDTTPAASSEPMEQSSNVQVDPPTLSGRPRKQLPSFDFNGPYLGPPQSHSLPDLPGQLVSPQGGGSLKPALPGSLEYMCLPPGGQVQLVPLSQVMGQGRDVDVQCGSSLETTESPSMESRESPPVELKEEEQEPRDNPVTLPISSGGPKDSKVASEYVTPADLVLTLPTEPLSTSLGPSLEVSSAQSPSLCLKLPRVPSESPALAPAVFEDYVELPPSMSQPAKSLPGNPAPPGPSSPAVSPGEPREEVGAAPTHPEGLLVLQQVGDYCFLPGLGPSPLSPPSKPPSPGLCLETEDLDKDLSVKKLPYQPIPQVPAIQFFKSLKHQDYLSLPPWDNSQPGKVC
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0140375 (immune receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0004896 (cytokine receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:1901700 (response to oxygen-containing compound), GO:0009617 (response to bacterium), GO:0043207 (response to external biotic stimulus), GO:0002237 (response to molecule of bacterial origin), GO:0033993 (response to lipid), GO:0032496 (response to lipopolysaccharide)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: RAD21 cohesin complex component (F7EK71)
Organism: Rattus norvegicus (Rat)
Function: May promote apoptosis
Subcellular location: Chromosome, centromere. Cytoplasm, cytosol. Nucleus
InterPro domains:
- IPR023093: ScpA-like, C-terminal (homologous_superfamily) [561-629]
- IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [562-632]
- IPR006909: Rad21/Rec8-like protein, C-terminal, eukaryotic (domain) [579-632]
- IPR049589: NXP-1, middle HEAT-repeat binding domain (domain) [316-395]
- IPR006910: Rad21/Rec8-like protein, N-terminal (domain) [1-103]
- IPR039781: Rad21/Rec8-like protein (family) [1-632]
Sequence:
MFYAHFVLSKRGPLAKIWLAAHWDKKLTKAHVFECNLESSVESIISPKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAAYNAITLPEEFHDFDQPLPDLDDIDVAQQFSLNQSRVEEITMREEVGNISILQENDFGDFGMDDREIMREGSAFEDDDMLVSTSASNLLLEPEQSTSNLNEKINHLEYEDQYKDDNFGEGNDGGILDDKLISNNDGGIFDDPPALSETGVMLPEQPAHDDMDEDDNGSLGGPDSPDSVDPVEPMPTMTDQTTLVPNEEEAFALEPIDITVKETKAKRKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTKKLMMWKETGGVEKLFSLPAQPLWNNRLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKEFENPEVPREEQQPQPQQQQAQRDVIDEPIIEEPSRLQDSVMEASRTNIEESAMPPPPPQGVKRKAGQVDPEPAIPQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEEEEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESISLLELCRNTNRKQAAAKFYSFLVLKKQQAIELTQEEPYSDIIATPGPRFHII
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0071310 (cellular response to organic substance), GO:0014070 (response to organic cyclic compound), GO:0071407 (cellular response to organic cyclic compound)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)