lokahq/bioreason-rl huggingface dataset:
Protein: V-type proton ATPase subunit a (A0A8M3AYX3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase
Subcellular location: Cytoplasmic vesicle, clathrin-coated vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Melanosome. Membrane; Multi-pass membrane protein
InterPro domains:
- IPR026028: ATPase, V0 complex, subunit 116kDa, eukaryotic (family) [1-863]
- IPR002490: V-type ATPase, V0 complex, 116kDa subunit family (family) [4-863]
Sequence:
MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGMVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVEKEIKKANIPTMDTGENPEVPFPRDMIDLEATFEKLENELKEINTNQEALKKNFLELTELKHILRRTQQFFDEMEDPNLLEESSSLLDPSEAGRGAPLRLGFVAGVINRERIPTFERMLWRVCRGNVFLRQTEIEDPLEDPTTGDQVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKTMRVWFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVSDLDSIQFALRRGTERSGSTVPSILNRMQTKQTPPTYNKTNKFTSGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDMGHGVLMTSAALYLVLRETRLLAQKSDNEMFNMIFAGRYIILLMGMFSVYTGLIYNDCFSKSLNMFSSGWSVRPMFAPNGNWTDQTLESNSVLQLNPSVSGVFGGPYPLGIDPIWNIAANKLTFLNSFKMKMSVILGVIHMLFGVTLSLFNHLYFKKPLNIFLNFIPEIVFMSSLFGYLILLIFYKWIAYDAVTSKDAPSLLIAFINMCLFNYNDPTNKPLYRGQAGIQSLLVVIALACVPVMLVVKTMILRRQHLWKKHLSQMRDARPAENLETLEQTGTSSPPGLTQQGTQKFGGVRVGNGPTEDEAEIIDHDQLSQHSEEGDEHSEEEPFNFGDMAVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWGMVMRLGLSSRSGGGFFGLSIIFSAFATLTVCILLIMEGLSAFLHALRLHWVEFQNKFYTGQGFKFVPFSFESILEGRFDE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0015078 (proton transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:0009410 (response to xenobiotic stimulus), GO:0070887 (cellular response to chemical stimulus), GO:0071466 (cellular response to xenobiotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)
Protein: Protein moonraker isoform X2 (A0A8M2B4L0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR031447: Protein moonraker (family) [9-876]
Sequence:
MISDFHRASTMTTADLGSLNRQWIKKGSSVSQIAGLQTQLQFNSAVLPSVLNRATRVGPPSPIVIEKLLPHTERQDDMESCSSSLRLSVLSEERLQAAVRLAKRDLQRKRQESINRSSLEQEETQEIIIPERTNTDNVPRVVSPKMAGTRKQIKTGAHVLVYTPQKPNSPIKQTQTPIKNTIVNSSEPQLTQEIRKLQKELSTYVQRVEQLANKECVVEALEPNEKQRIEIRRQEQAARSARMIYVLQQQVKEIKQDLDKLRCQNIKPTKKSRPMERLAAAHRGAVRAMQVFINQLSDPAENRVPTHCKELGQLIRQLSLCSAKVEVGQGSVVPETALDILQKLEMLDSALSKQETTKKRDVYLQNVNPVEKTSIQVRARSMSPPRPARAPAERNSRRPRKPADAKKPASSRLAGKSHRTSQALLKERNDVLKAGLESLIHHQKLREAEAQKTNKTTSAISQDHVKASHVRDAKFQQPTVSSRLRENQVPQKESTVPWIPTSPHSPSRLRAVPNRPEPRCLFSPHKNPEKQKPQTTSSTQLSASSPDRKQAQNEALRQAWLDRVTADRLRELNRLSKEEADRIKKLRTTVGSPTQWAERAERAAKERIQPLLDQAQRVAGAGSDRLRARLKVTDKAEGKTDLLTETLLEDLQEDTAQALWVTQREQVAETDAERKLQGPTLESMLLRMEEMERDQDEVRRRLAMISYSDPLIWERGTDATRNNSSSRPISPQPIRLTKPALNAPPTADILLQKPVEIGAASDMPILDDESLTPNDSSNPVPAGGGSTRGVYLTVPASMQRRIQKYRENHDAFLRLISHEALGSFNPWAIADSLADELMSEALAEVAAEFQDVCEEYAEAVFTSEFLQPVQSPSTSMS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0048856 (anatomical structure development), GO:1904888 (cranial skeletal system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0036064 (ciliary basal body), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0005929 (cilium), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015630 (microtubule cytoskeleton)
Protein: RNA helicase (A0A8M2BF54)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm
InterPro domains:
- IPR001650: Helicase, C-terminal domain-like (domain) [446-607]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [167-612]
- IPR011545: DEAD/DEAH-box helicase domain (domain) [231-422]
- IPR014014: RNA helicase, DEAD-box type, Q motif (domain) [207-235]
- IPR000629: ATP-dependent RNA helicase DEAD-box, conserved site (conserved_site) [377-385]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [226-450]
Sequence:
MSHVVVDGSHGLDQQLAVLDLNSADGQGVGTGHSPGWDGSRTNGFVNGYHDSRMNGTANFARGPLRNDRGGRGGFRGNRNGASFNQPVHNAGYGTYENKDGGWNSVVNRDAYASFGGRSDRGKSAFFNDRGASSRGRYERGGFGGGTGGNSRWVEESRDEEDWSKPMPPNERLEHELFSASNTGINFEKYDDIPVEATGTNSPGHIESFHDVDMGEIIMGNITLSRYTRPTPVQKYAIPIIKTKRDLMACAQTGSGKTAAFLLPVLSQIYSEGPGEALQATKASTQQENGKYVRRKQYPISLVLAPTRELALQIYDEARKFAYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDYCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGSRQTMMFSATFPKEIQILARDFLEEYIFLAVGRVGSTSENITQKVVWVEENDKRSFLLDLLNATGKDSLTLVFVETKKGADALEDFLYREGYACTSIHGDRSQRDREEALHQFRSGRCPIMVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFYNDKNSNITKDLLDILVEAKQEVPSWLENLAYEHQHKSTNRGRPKRFSGGFGARDYRQMPGGGNTFGNRGARNTGGHGGNRGFGGNKGGFGSFGGDSYGGTYGNYGGNYTQVDWWGN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0048870 (cell motility), GO:0042221 (response to chemical), GO:0050900 (leukocyte migration), GO:0042330 (taxis), GO:0097529 (myeloid leukocyte migration), GO:0006935 (chemotaxis), GO:0030595 (leukocyte chemotaxis), GO:0070887 (cellular response to chemical stimulus), GO:0016477 (cell migration), GO:0071621 (granulocyte chemotaxis), GO:0060326 (cell chemotaxis), GO:0097530 (granulocyte migration), GO:1990266 (neutrophil migration), GO:0030593 (neutrophil chemotaxis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0043229 (intracellular organelle), GO:0035770 (ribonucleoprotein granule), GO:0036464 (cytoplasmic ribonucleoprotein granule), GO:0045495 (pole plasm), GO:0043228 (non-membrane-bounded organelle), GO:0043186 (P granule), GO:0060293 (germ plasm), GO:0043232 (intracellular non-membrane-bounded organelle)
Protein: Stress-activated protein kinase JNK (A0A8M3AWM8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Responds to activation by environmental stress and pro- inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity
Subcellular location: Cytoplasm
InterPro domains:
- IPR003527: Mitogen-activated protein (MAP) kinase, conserved site (conserved_site) [102-204]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [188-200]
- IPR000719: Protein kinase domain (domain) [67-362]
- IPR050117: Mitogen-activated protein (MAP) kinase (family) [65-388]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [55-384]
- IPR008351: Mitogen-activated protein (MAP) kinase, JNK (family) [117-376]
Sequence:
MVFMNRRFLYNCSAPVLDVKIAFCQGFGKQVDVSYIAQHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAGYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPSPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDCLFPADSEHNKLKASQARDLLSKMLIIDPAKRISVDEALQHPYINVWYDPAEVEAARNQQISMPPPQIYDKQLDEREHSIDEWKELIYKEVMNFEERTKNGVVKGQPSPSGAAVNSSESLPPSSSVNDISSMSTDQTLASDTDSSLETSAGPLGCCR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity), GO:0004707 (MAP kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048732 (gland development), GO:0048483 (autonomic nervous system development), GO:0007399 (nervous system development), GO:0061008 (hepaticobiliary system development), GO:0048484 (enteric nervous system development), GO:0001889 (liver development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: mitogen-activated protein kinase kinase (A0A8M2B6X1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR052468: Dual specificity MAP kinase kinase (family) [2-413]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [240-252]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [119-385]
- IPR000719: Protein kinase domain (domain) [121-381]
Sequence:
MSSLEQRLSRIEEKLKQENKEARKRIDLNIDMSPQRTRPRPTLQLPLANDGGSRSSSSESSPQHPSYPNRPRQMLTLPTTPYNLQKNLENAEIDQKLQEIMKQTGYLKIDGQRYPAEVTDLISEGEIGSGTCGQVFKVRFKKTGHVIAVKQMRRTGNKDENKRILMDLDVVLKSHDCPYIIQCYGAIVTNTDVFIAMELMGTCAEKLKKRIQGPIPEAILGKMTVAIVNALLYLKEKHGVIHRDVKPSNILLDAKGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPSKPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEDPPVLPLSMGFSPDFQSFVKDCLTKDHRKRPKYHKLLEHSFIRRYEVSEVDVAGWFQAVMERTESPRSSQCFSHHQLHSLFSR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004712 (protein serine/threonine/tyrosine kinase activity), GO:0016301 (kinase activity), GO:0004708 (MAP kinase kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0007389 (pattern specification process), GO:0009790 (embryo development), GO:0001756 (somitogenesis), GO:0009888 (tissue development), GO:0003002 (regionalization), GO:0035282 (segmentation), GO:0061053 (somite development), GO:0060429 (epithelium development), GO:0009952 (anterior/posterior pattern specification), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: ubiquitinyl hydrolase 1 (A0A8M3B6G9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR018200: Ubiquitin specific protease, conserved site (conserved_site) [169-610]
- IPR001394: Peptidase C19, ubiquitin carboxyl-terminal hydrolase (domain) [168-656]
- IPR028889: Ubiquitin specific protease UPS, catalytic domain (domain) [168-659]
- IPR009060: UBA-like superfamily (homologous_superfamily) [4-72]
- IPR003903: Ubiquitin interacting motif (conserved_site) [30-142]
- IPR054109: UBA-like domain (domain) [15-59]
- IPR054108: Ubiquitin carboxyl-terminal hydrolase 25/28, UIM (conserved_site) [81-131]
- IPR038765: Papain-like cysteine peptidase superfamily (homologous_superfamily) [163-656]
- IPR050164: Ubiquitin carboxyl-terminal hydrolases (family) [111-659]
Sequence:
MTVEQNVLQQHSQKHQQTLLNQLREVTGTTDVQLLQQALQVSNGDLVEAVAFLTEKNAKVPQQDEATYYQTAQITNDRYISVGSQADTNVIDLTGDDKDDLQRAIALSLEESNRAFRETGITDEEQAISRVLEASIAENKASLKRTHTEVWSDSPNPHERKRMENCPVGLKNVGNTCWFSAVIQSLFNLLEFQRLVLHYSPPARMQDLPRNQKEHRNLPFMQELRHLFSLLVGSKRKYVDPSGAVEILKDAFKSSESQQQDVSEFTHKLLDWLEDAFQIKAEEDREGEKPKNPMVELFYGRFLAVGVLEGKKFENTEMFGQYPLQVNGFKDLHECLEAAMIEGEIESLHSAENSAKSGQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPSMLYMDRYMDRNREITRIKREEIRRLKEHLTVLQQRLERYLSYGSGPKRFPLADVLQYAMEFASSKPVCTSPVEDIDTTAPPGGTIAQLPPPASAGEQPDACVSAEGSGSGLQASQQQQQRVSIHKPFTQSRVPPDLPMHPAPRHITEEELRVLESCLHRWRSEVENDTRDLQASISRIHRTIELMYSDKSMMQVPYRLHAVLVHEGQANAGHYWAYIYDRHHQRWMKYNDIAVTKSSWEELVRDSFGGYRNASAYCLMYIDDKKPFLIQEEFDKETGQMLSGLDKLPPDLKVFVEADNKLFEREMEEWDALQARKLQQEKLALAAAAAAAAAASVAVQPMSTEPCSPDNTAPSAAPQHDPEYMEQQSPSGDSKHLQEDTERAISKAAAEHDEKSPEALLNTSQSSHPDSKLTSDPCPPPDPEQDDPTCPPPGPQRVVEVAIPNVGTFVIQSKEGGYDDEAMMTPNMQGIIMAIGKSRSVYDKCGPEAAFFKAMKVEYTRLLRLAQEDTPPERDYRLQHVIVFFIHNEAPKKIVERTLLMQFADRNLGFDERCKSIMKVARAKLELIKPDEVNLEEYEMWHQDYRIFRETSVFLLIGLELFMKKSFVEALMYLIYAYQYNKELLAKGPYRGHDEELIAHYRRECLLKLNEYAAALFETGEEAKVNTGLSIMNDLVVPCLPLLLVDEMEEKDMVAVEDMRNRWCSYLGQEMEPNLQEKLTDFLPKLLDCSTEIKSFHEPPKLPSYSTLELFERFGRVMTSLTMGRTPADGR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0007389 (pattern specification process), GO:1904888 (cranial skeletal system development), GO:0003002 (regionalization), GO:0009953 (dorsal/ventral pattern formation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Macrophage receptor MARCO isoform X4 (A0A8M9QFQ5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Single- pass type II membrane protein
InterPro domains:
Sequence:
METEVDDFPGKASIFSQVNPLYSNNMKLCEAERYDFQHSEPKTMKSASKRHCVPVLILLFLLLIGLNSFLAYKVFTLEAWVHTHCTSAQNHELTSASSFQLGSSKNEVECFTDLCGTDGTLEHLRTQINQLNATAEKAIVCPPGPPGPPGSNGIPGFPGQKGIPGSPGRVGEPGAPGQKGQTGDPGIKGERGMVGFPGIPGAPGRKGDSGERGLQGLPGNDGSPGQDGRTGPQGMPGPSGSQGVKGDPGLKGERGDQGPPGPTGPQGSSGARGLQGIPGEKGSPGPKGDTGVGLQGLTGQQGQKGSQGLPGVPGARGANGEKGDRGLSGQKGDQGPKGEKGDAGAKGASGGSQVVRLVGSSTRGRVEVFYQNVWGTVCDDSFDNLDALVVCRMLGFQRSTQVYTDGSGSGRIWLDELRCTGTESSIFNCPHAGMGINNCGHGEDVGVSCA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0051234 (establishment of localization), GO:0009605 (response to external stimulus), GO:0006950 (response to stress), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006952 (defense response), GO:0043207 (response to external biotic stimulus), GO:0009617 (response to bacterium), GO:0006810 (transport), GO:0098542 (defense response to other organism), GO:0016192 (vesicle-mediated transport), GO:0042742 (defense response to bacterium), GO:0006909 (phagocytosis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0030139 (endocytic vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0031982 (vesicle), GO:0030659 (cytoplasmic vesicle membrane), GO:0012506 (vesicle membrane), GO:0030666 (endocytic vesicle membrane), GO:0097708 (intracellular vesicle)
Protein: Myelin basic protein (A0A8M2B444)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Myelin membrane; Peripheral membrane protein; Cytoplasmic side
InterPro domains:
- IPR000548: Myelin basic protein (family) [3-129]
Sequence:
MSMGQHLGKREPLSVSKGSSTVSEHINSTDTPAESQDEVFGLGEADLNQNNGCSSKSPVVTDSMNAEVHHSSWNQPNTVDPNASGPRPHLVRLFSRDAPGREDNTFKDRPSESDELQTIHEHGGAGSECESEGTE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0043473 (pigmentation), GO:0048066 (developmental pigmentation), GO:0048869 (cellular developmental process), GO:0030154 (cell differentiation), GO:0050931 (pigment cell differentiation), GO:0030318 (melanocyte differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0043209 (myelin sheath), GO:0005886 (plasma membrane)
Protein: non-specific serine/threonine protein kinase (A0A8M3AY27)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [147-159]
- IPR000719: Protein kinase domain (domain) [28-281]
- IPR051234: TAO Serine/Threonine-Protein Kinase (family) [1-840]
- IPR017441: Protein kinase, ATP binding site (binding_site) [34-58]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [28-282]
Sequence:
MPSSVRAGSLKDPEVAELFYKEDPEKLFTDLREIGHGSFGAVYFAHDIRTNEVVAIKKMSYSGKQSNEKWQDIIKEVKFLQKLRHPNTVEYRGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLVYLHSHNMIHRDVKAGNILLTEPGQVKLGDFGSASIVAPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSNHWSDYFRNFVDSCLQKISQDRPTSDVLLKHHFLCRERPVTVVMDLIARTKDAVRELDNLQYRKMKKILFQETHNGPATEGTEEEESCVFQDVEQYMLRTGTVNSMESSHSLPSMSISASSQSSSVNSLADGSDDSGEMAMMQEGEHTVTSNSSVLHKALNHDNIYDDPYQPEMDSQQQQQQGPSGGRRRRGRDHFATIRTASLVTRQIQEHEQGSALREQMSGYKRMRRQHQKQLMALENKLKAEMDEHQLRLDKELETQRNNFGSEADKLSKKHQAILEKETKGAIAEEKKFQQHILGQQKKELTSLLESQKRHYRQRKEQLKEELNENQSTPKREKQEWLVQQKECLQQVQAEEEAGLLRRQRQYYELQGRQYKRKMLLSRHNLEQDLLREDLNKKQTLKDLECAMLLRHHESTQELEFRQLALVQRTRADLIRTQHQTELTNQMEYNKRREQELRQKHAVEVRQQPKSLRVSDSDITENTTEGAGLDIEGVEPQDEEKRDGEKIDGDEMQPLGAVEETSEQEMREVNVLEENDTEETLTDQCDVIDSEGKVEELAESADNVNESADKSPKIADEEQVEDKIDNDLRQVEGLQWDGESESDSAEEDRGVADGCPSELIPGPSFERRPLERDLDELSEFYFPDTLEELEPPPVYIPPSPSSSSQPSLPSLFSHAICLVLSLSAAVQPSVLTLLLLSIFLLSLRRSPPLPSLASILLSGELAFLALFFSYLFLRSCCSLSFSTYLLLTYWGSGLFSLALSLSLGLYYVPIALISASFLSSPSLFLTLYLIVVLVVRPARVFLQNTPRKLNRLWMRVLFRLPKPLFTVCQSVLGGLTERSLYDMFPKAGRNWGGRQSRIPVPLKSLHTAQYQAKSKHSLLFARILLMGRRFVRRPLGTLTDLANSMVLHIAKRVLKELPQNYLKRLQEFGLLRKEKTSKLPVLLPRMVREHRRRMRERRETERRRRVERERMYREEGRWESVLRRTASGRSLKGKMVPWR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity), GO:0004709 (MAP kinase kinase kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0030901 (midbrain development), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Galactose-1-phosphate uridylyltransferase (A0A8M9QC62)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
Sequence:
MDMNNKPTFDPKEHQHLRYNPLRDSWVLVSAHRMKRPWKGQVEKPPEDNIPRHDPNNPLCPGSVRANGELNPEYDSTFMFDNDFPALQPDAPDPGSDHHPLFQSKAARGVCKVMCFHPWSDITLPLMQPAEIRKVIDKWADLTVELGATYAWVQIFENKGAMMGCSNPHPHCQHHRFFPPPPSCISI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016779 (nucleotidyltransferase activity), GO:0070569 (uridylyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:0005996 (monosaccharide metabolic process), GO:0005975 (carbohydrate metabolic process), GO:0019318 (hexose metabolic process), GO:0006012 (galactose metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)