Protein: Adenylate cyclase (A0A2H0ZFS7)
Organism: Candida auris (Yeast)
Function: Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP
InterPro domains:
- IPR050216: Leucine-rich repeat domain-containing protein (family) [649-870]
- IPR029787: Nucleotide cyclase (homologous_superfamily) [1589-1831]
- IPR055414: Disease resistance R13L4/SHOC-2-like, LRR domain (domain) [784-1024]
- IPR048580: Adenylate cyclase, C-terminal, yeast (domain) [1853-1928]
- IPR003591: Leucine-rich repeat, typical subtype (repeat) [763-1168]
- IPR036457: PPM-type phosphatase-like domain superfamily (homologous_superfamily) [1257-1568]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [647-1257]
- IPR001054: Adenylyl cyclase class-3/4/guanylyl cyclase (domain) [1513-1818]
- IPR001611: Leucine-rich repeat (repeat) [811-1146]
- IPR000159: Ras-associating domain (domain) [555-645]
- IPR055071: PHLPP-like, RA domain (domain) [559-650]
- IPR001932: PPM-type phosphatase-like domain (domain) [1267-1547]
Sequence:
MTFLRKDKSKSDLRSVFSMSSAGGTQGGQEGASEQRIEQASDTASGAGAEASNTEASGSHEKREKSSVTPKLSMTSFSAPSSRKPSTTPLSHPASQRVPAGVSEQRHSFKPSALATSTSVPEPSPTNTNFSASSVAFNSTRGNQHNATSGSLSPVSSSGSGSSDHHAPYRLEARSRSSGSVVNDDQQNQASSQGRPNFYRTNTTENYSPRSSVVSMQQSPEQNESHANDDSVLKNNYRGFHGTKAPQANVPPLSHPIKPRFRKKGSSLLNKLIHSNRKDSEVSADHEASSGGRKSGGSLSHAADHKGSTSSGSSKHKFRLPSISSYHHHQHQGASSQGHSDASSRHASISEEASSRSGKGTGETPRRKSASSASDALQSSPSKVFDLDLNFDEMQSILRKPDKAPIRPSLKSANNSSTDVSDPVKGEDHVKPAAGWQAPNSWDVTGEIPNPASVTSTAVANEAQSDHSLNSDLSKTDDGGEVSHKVGNKSSSSSVRSSASSKEGPQATVIDHSASVEKKRKSEPRTAAPRRRLPILFGTWANRSPAVESKLAKGPNHIVRVFKEDNTFTTILCPLETNAAELLRIVQRKFFFESISNYHLALYVGRNVKVLEPFEKPLKIQMGLLSLSGYTENDNFRIIGREDLSFVCKLVVENKVLRNLTHEEESLVTKDYVDVDISGLDLKNIPIIFHQHTYEIEKLNVSDNPAIYIPLDFIQSCTNLSAINFSRNGCSKFPVNFLEARDLTSLNMEANFLDELPSKFGVLSNLVTLKLNSNQLYDLPKSFGKLNNLTHLNLSSNYFEDYPECINDLTNLQDLDLSYNDLYHIPDSIAKLSKLVKLNLCTNKLSGNIPDSFKSLINLKRLDIRYNQISNVDVLGDLPSLEVVYASKNKISAFNDKMEKLRLLHFDRNPITNLEFEILLPMLTVLDLSKAKLTMLPSEFVTKIPHIEKLVLDKNHLVNLPEELGDLPRLTHLSLYGNNIQGIPVSIGKLHSLQYLDLHSNNISSLPDEIWNLKSLSVLNVASNLLSSFPQPSFAIAKKISSSVNLRQDGVESLEEANELNASALKEGPVSLADSLLSLTLADNRLSDDCFEAISLLTQLKCLNLAYNDILEIPEGGLANLKKLSELYLSGNGLTKLPADDLEELSALRLLFLNNNKLTTLPSEISKLENLTYFDAGSNLLRYNISNWPYDWNWFANPKLRYLNFSGNKRFEIKQSYVKNPVTGEDLDSLLVLKNLKVLGLMDVTLTTPAVPDPGVDVRLRTASSELDNVGYGVSDSMGLREHISFRDVFMQKFRGNENEQLLCSFDGKSGGHQVMGHLLSHLTKQIFVPNLTYELNKISSDHEIADAMRRAFLSLNKEINAVFAAKKGGYFAPNTVSPELASIKIPDDSLNGCTMCALYIKDKTIYCGNIGDIQLVLSKSNGEHVLLTTNHDPTSRDEFERVRACGGYVSGDGALDGTLQVSRGAGFFDYLPHTHSGPSISTYPLSGNDDVLVMGTRVLWDFVSYDLAVDILRQAKEDPMIAAQKLRDYAIGYGATDKISVNVISIGDRKSKKKKSLYNNLGRETDLFANKRRRDRGAQSGDTALRALDNEIEPPVGDLALVFTDIKNSTLLWDTYPVAMRSAIKLHNTIMRRQLRIVGGYEVKTEGDSFMVTFPSPTSALLWCFNVQYQLLNEEWPSEILETNECCEVTDGDNNVIFRGLSVRMGIHWGSPVCELDMVTRRMDYFGPMVNRASRIESSADGGQIAVSSDFLHEMEQLYHIHDSIKIGELSLEAAYEGNLRAGEIIEKEIASLEEMGVSYFPLGERKLKGLETPEMITLVYPKRLELRFEIFKKRADEDDQYKGRIVGAVPVDAVYQLRTLSLRLENICAAVNVGMRMDENFSKHSSEIISESTAKRFKEMELVALLNHSVTRIENSIANLELRQTLLRRNGGNGRIDFFGSPDIWTLMDEVKQFIKSANIS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0009975 (cyclase activity), GO:0004016 (adenylate cyclase activity), GO:0016849 (phosphorus-oxygen lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0009605 (response to external stimulus), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0048584 (positive regulation of response to stimulus), GO:0009607 (response to biotic stimulus), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0051707 (response to other organism), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0044238 (primary metabolic process), GO:0006793 (phosphorus metabolic process), GO:0002831 (regulation of response to biotic stimulus), GO:0032103 (positive regulation of response to external stimulus), GO:1901576 (organic substance biosynthetic process), GO:0043207 (response to external biotic stimulus), GO:0006629 (lipid metabolic process), GO:0002833 (positive regulation of response to biotic stimulus), GO:0080134 (regulation of response to stress), GO:0009617 (response to bacterium), GO:0019637 (organophosphate metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0006952 (defense response), GO:0032101 (regulation of response to external stimulus), GO:0044249 (cellular biosynthetic process), GO:0031349 (positive regulation of defense response), GO:0098542 (defense response to other organism), GO:0006793 (phosphorus metabolic process), GO:0031347 (regulation of defense response), GO:0046486 (glycerolipid metabolic process), GO:1900426 (positive regulation of defense response to bacterium), GO:0006644 (phospholipid metabolic process), GO:0042742 (defense response to bacterium), GO:0090407 (organophosphate biosynthetic process), GO:0006796 (phosphate-containing compound metabolic process), GO:1900424 (regulation of defense response to bacterium), GO:0008610 (lipid biosynthetic process), GO:0045017 (glycerolipid biosynthetic process), GO:0006650 (glycerophospholipid metabolic process), GO:0008654 (phospholipid biosynthetic process), GO:0046474 (glycerophospholipid biosynthetic process), GO:0006661 (phosphatidylinositol biosynthetic process), GO:0046488 (phosphatidylinositol metabolic process), GO:0046854 (phosphatidylinositol phosphate biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)