Protein: T-cell surface glycoprotein CD3 epsilon chain (A6J423)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Single- pass type I membrane protein
InterPro domains:
- IPR015484: CD3 protein, epsilon/gamma/delta subunit (family) [1-188]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [17-103]
- IPR003598: Immunoglobulin subtype 2 (domain) [28-85]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [25-90]
- IPR007110: Immunoglobulin-like domain (domain) [30-88]
- IPR003110: Phosphorylated immunoreceptor signalling ITAM (repeat) [159-186]
Sequence:
MQWNAFWSILGLSLLAVGTCQEEYEVSISGTSVELTCPLENEDNLKWEKNDKVLPDKNEKHLVLEDFSEVKDSGYYVCYTESSRKNTYLYLKARVCENCMEVDLTAVSIIIIVDICITLGLLMVVYYWSKKRKAKAKPVTRGTGTGGRPRGKAQGQNKERPPPVPNPDYEPIRKGQRDLYSGLNQRAV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0001775 (cell activation), GO:0042221 (response to chemical), GO:0045321 (leukocyte activation), GO:0051240 (positive regulation of multicellular organismal process), GO:0002684 (positive regulation of immune system process), GO:0050794 (regulation of cellular process), GO:0002682 (regulation of immune system process), GO:0051239 (regulation of multicellular organismal process), GO:0048522 (positive regulation of cellular process), GO:0009991 (response to extracellular stimulus), GO:0002696 (positive regulation of leukocyte activation), GO:0042127 (regulation of cell population proliferation), GO:0007584 (response to nutrient), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0030155 (regulation of cell adhesion), GO:0002694 (regulation of leukocyte activation), GO:0045785 (positive regulation of cell adhesion), GO:0050865 (regulation of cell activation), GO:0046649 (lymphocyte activation), GO:0050867 (positive regulation of cell activation), GO:0008284 (positive regulation of cell population proliferation), GO:0030097 (hemopoiesis), GO:0051251 (positive regulation of lymphocyte activation), GO:0002521 (leukocyte differentiation), GO:0022409 (positive regulation of cell-cell adhesion), GO:0031667 (response to nutrient levels), GO:0022407 (regulation of cell-cell adhesion), GO:0042110 (T cell activation), GO:0070665 (positive regulation of leukocyte proliferation), GO:0070663 (regulation of leukocyte proliferation), GO:0030098 (lymphocyte differentiation), GO:0051249 (regulation of lymphocyte activation), GO:0032946 (positive regulation of mononuclear cell proliferation), GO:0050670 (regulation of lymphocyte proliferation), GO:0050870 (positive regulation of T cell activation), GO:0050863 (regulation of T cell activation), GO:0032944 (regulation of mononuclear cell proliferation), GO:1903131 (mononuclear cell differentiation), GO:0030217 (T cell differentiation), GO:1903037 (regulation of leukocyte cell-cell adhesion), GO:1903039 (positive regulation of leukocyte cell-cell adhesion), GO:0050671 (positive regulation of lymphocyte proliferation), GO:0042102 (positive regulation of T cell proliferation), GO:0042129 (regulation of T cell proliferation), GO:0033077 (T cell differentiation in thymus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0043235 (receptor complex), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:0098802 (plasma membrane signaling receptor complex), GO:0098797 (plasma membrane protein complex), GO:0005886 (plasma membrane), GO:0042101 (T cell receptor complex)