Protein: Peroxisome proliferator-activated receptor beta (A6JJP8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR003075: Peroxisome proliferator-activated receptor, beta (family) [54-387]
- IPR000536: Nuclear hormone receptor, ligand-binding domain (domain) [210-438]
- IPR013088: Zinc finger, NHR/GATA-type (homologous_superfamily) [65-151]
- IPR003074: Peroxisome proliferator-activated receptor (family) [163-433]
- IPR035500: Nuclear hormone receptor-like domain superfamily (homologous_superfamily) [169-440]
- IPR001628: Zinc finger, nuclear hormone receptor-type (domain) [70-144]
- IPR050234: Nuclear hormone receptor family NR1 subfamily (family) [55-437]
- IPR001723: Nuclear hormone receptor (family) [133-414]
Sequence:
MEQPQEETPEAREEEKEEVATGDGAPELNGGPEHTLPSSSCTDLSQNSSPSSLLDQLQMGCDGASGGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLKYEKCDRICKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTASEGCQQNPQLADLKAFSKHIYNAYLKNFNMTKKKARSILTGKSSHNAPFIIHDIETLWQAEKGLVWKQLVNGPPPYNEISVHVFYRCQSTTVETVRELTEFAKNIPNFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTHEFLRSIRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPQVEAIQDTILQALEFHLQVNHPDSQYLFPKLLQKMADLRQLVTEHAQMMQWLKKTESETLLHPLLQEIYKDMY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0036094 (small molecule binding), GO:0003700 (DNA-binding transcription factor activity), GO:0008289 (lipid binding), GO:0038023 (signaling receptor activity), GO:0097159 (organic cyclic compound binding), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0008134 (transcription factor binding), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific), GO:0005504 (fatty acid binding), GO:0004879 (nuclear receptor activity), GO:0098531 (ligand-activated transcription factor activity), GO:0043177 (organic acid binding), GO:0043168 (anion binding), GO:0140297 (DNA-binding transcription factor binding), GO:0031406 (carboxylic acid binding), GO:0061629 (RNA polymerase II-specific DNA-binding transcription factor binding), GO:0033293 (monocarboxylic acid binding), GO:0051059 (NF-kappaB binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0008152 (metabolic process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0022414 (reproductive process), GO:0048519 (negative regulation of biological process), GO:0009605 (response to external stimulus), GO:0048856 (anatomical structure development), GO:0042221 (response to chemical), GO:0006807 (nitrogen compound metabolic process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0051050 (positive regulation of transport), GO:0009892 (negative regulation of metabolic process), GO:0065008 (regulation of biological quality), GO:0050793 (regulation of developmental process), GO:0044706 (multi-multicellular organism process), GO:0009607 (response to biotic stimulus), GO:0050794 (regulation of cellular process), GO:0044703 (multi-organism reproductive process), GO:0048583 (regulation of response to stimulus), GO:0040013 (negative regulation of locomotion), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0051707 (response to other organism), GO:0040012 (regulation of locomotion), GO:0023056 (positive regulation of signaling), GO:0007275 (multicellular organism development), GO:0009058 (biosynthetic process), GO:0007566 (embryo implantation), GO:0019222 (regulation of metabolic process), GO:0032879 (regulation of localization), GO:0071704 (organic substance metabolic process), GO:0014823 (response to activity), GO:0003008 (system process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0009893 (positive regulation of metabolic process), GO:0045926 (negative regulation of growth), GO:0051094 (positive regulation of developmental process), GO:0048609 (multicellular organismal reproductive process), GO:0048585 (negative regulation of response to stimulus), GO:0040008 (regulation of growth), GO:0044238 (primary metabolic process), GO:0048522 (positive regulation of cellular process), GO:0051047 (positive regulation of secretion), GO:0043207 (response to external biotic stimulus), GO:2000145 (regulation of cell motility), GO:0060548 (negative regulation of cell death), GO:0080134 (regulation of response to stress), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0044255 (cellular lipid metabolic process), GO:0032101 (regulation of response to external stimulus), GO:0060135 (maternal process involved in female pregnancy), GO:0010712 (regulation of collagen metabolic process), GO:0003013 (circulatory system process), GO:1901135 (carbohydrate derivative metabolic process), GO:0031348 (negative regulation of defense response), GO:0006793 (phosphorus metabolic process), GO:0006082 (organic acid metabolic process), GO:0030308 (negative regulation of cell growth), GO:0001893 (maternal placenta development), GO:0051128 (regulation of cellular component organization), GO:0044260 (cellular macromolecule metabolic process), GO:0090066 (regulation of anatomical structure size), GO:0045684 (positive regulation of epidermis development), GO:2000146 (negative regulation of cell motility), GO:1903530 (regulation of secretion by cell), GO:0045682 (regulation of epidermis development), GO:1903829 (positive regulation of protein localization), GO:0051049 (regulation of transport), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0046887 (positive regulation of hormone secretion), GO:0060341 (regulation of cellular localization), GO:0008285 (negative regulation of cell population proliferation), GO:0019637 (organophosphate metabolic process), GO:0019538 (protein metabolic process), GO:0001558 (regulation of cell growth), GO:1901700 (response to oxygen-containing compound), GO:0006766 (vitamin metabolic process), GO:0010817 (regulation of hormone levels), GO:0043170 (macromolecule metabolic process), GO:0010033 (response to organic substance), GO:0071216 (cellular response to biotic stimulus), GO:0046883 (regulation of hormone secretion), GO:0009991 (response to extracellular stimulus), GO:0062013 (positive regulation of small molecule metabolic process), GO:0007565 (female pregnancy), GO:0042127 (regulation of cell population proliferation), GO:0006629 (lipid metabolic process), GO:0010941 (regulation of cell death), GO:0007584 (response to nutrient), GO:0009888 (tissue development), GO:0010646 (regulation of cell communication), GO:0031325 (positive regulation of cellular metabolic process), GO:0070887 (cellular response to chemical stimulus), GO:0009617 (response to bacterium), GO:0009889 (regulation of biosynthetic process), GO:0062012 (regulation of small molecule metabolic process), GO:0010647 (positive regulation of cell communication), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0010713 (negative regulation of collagen metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0051222 (positive regulation of protein transport), GO:0045834 (positive regulation of lipid metabolic process), GO:0046697 (decidualization), GO:1903532 (positive regulation of secretion by cell), GO:0032102 (negative regulation of response to external stimulus), GO:0031347 (regulation of defense response), GO:0006720 (isoprenoid metabolic process), GO:0008015 (blood circulation), GO:0043069 (negative regulation of programmed cell death), GO:1904951 (positive regulation of establishment of protein localization), GO:0043436 (oxoacid metabolic process), GO:0043067 (regulation of programmed cell death), GO:0006644 (phospholipid metabolic process), GO:0070201 (regulation of establishment of protein localization), GO:0002793 (positive regulation of peptide secretion), GO:0002237 (response to molecule of bacterial origin), GO:0030334 (regulation of cell migration), GO:0033273 (response to vitamin), GO:0048662 (negative regulation of smooth muscle cell proliferation), GO:0048660 (regulation of smooth muscle cell proliferation), GO:0006631 (fatty acid metabolic process), GO:0051223 (regulation of protein transport), GO:0090276 (regulation of peptide hormone secretion), GO:0045923 (positive regulation of fatty acid metabolic process), GO:0009100 (glycoprotein metabolic process), GO:0031667 (response to nutrient levels), GO:0072359 (circulatory system development), GO:0090407 (organophosphate biosynthetic process), GO:0030258 (lipid modification), GO:0050708 (regulation of protein secretion), GO:1901701 (cellular response to oxygen-containing compound), GO:0008610 (lipid biosynthetic process), GO:0007507 (heart development), GO:0003018 (vascular process in circulatory system), GO:0009743 (response to carbohydrate), GO:0050728 (negative regulation of inflammatory response), GO:0071219 (cellular response to molecule of bacterial origin), GO:0010565 (regulation of cellular ketone metabolic process), GO:0032496 (response to lipopolysaccharide), GO:0071310 (cellular response to organic substance), GO:0006796 (phosphate-containing compound metabolic process), GO:0032880 (regulation of protein localization), GO:0050714 (positive regulation of protein secretion), GO:0006775 (fat-soluble vitamin metabolic process), GO:0001890 (placenta development), GO:0032966 (negative regulation of collagen biosynthetic process), GO:0030336 (negative regulation of cell migration), GO:0035150 (regulation of tube size), GO:0032965 (regulation of collagen biosynthetic process), GO:0050727 (regulation of inflammatory response), GO:0090087 (regulation of peptide transport), GO:0033993 (response to lipid), GO:0051046 (regulation of secretion), GO:0090277 (positive regulation of peptide hormone secretion), GO:0019216 (regulation of lipid metabolic process), GO:0071222 (cellular response to lipopolysaccharide), GO:0042981 (regulation of apoptotic process), GO:0032024 (positive regulation of insulin secretion), GO:0006029 (proteoglycan metabolic process), GO:0014912 (negative regulation of smooth muscle cell migration), GO:0061178 (regulation of insulin secretion involved in cellular response to glucose stimulus), GO:0050796 (regulation of insulin secretion), GO:0033189 (response to vitamin A), GO:0046321 (positive regulation of fatty acid oxidation), GO:0019752 (carboxylic acid metabolic process), GO:0097746 (blood vessel diameter maintenance), GO:0008654 (phospholipid biosynthetic process), GO:0035774 (positive regulation of insulin secretion involved in cellular response to glucose stimulus), GO:0019395 (fatty acid oxidation), GO:0035296 (regulation of tube diameter), GO:0006721 (terpenoid metabolic process), GO:0019217 (regulation of fatty acid metabolic process), GO:0043066 (negative regulation of apoptotic process), GO:0014910 (regulation of smooth muscle cell migration), GO:0034284 (response to monosaccharide), GO:0071396 (cellular response to lipid), GO:0002791 (regulation of peptide secretion), GO:0034440 (lipid oxidation), GO:0016101 (diterpenoid metabolic process), GO:0042311 (vasodilation), GO:0032787 (monocarboxylic acid metabolic process), GO:0046320 (regulation of fatty acid oxidation), GO:0009746 (response to hexose), GO:0009749 (response to glucose), GO:0001523 (retinoid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)