lokahq/bioreason-rl huggingface dataset:
Protein: Serine (Or cysteine) peptidase inhibitor, clade F, member 1, isoform CRA_b (A6HGQ2)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR023795: Serpin, conserved site (conserved_site) [213-223]
- IPR036186: Serpin superfamily (homologous_superfamily) [75-240]
- IPR000215: Serpin family (family) [78-241]
- IPR023796: Serpin domain (domain) [2-240]
- IPR042178: Serpin superfamily, domain 1 (homologous_superfamily) [145-186]
- IPR042185: Serpin superfamily, domain 2 (homologous_superfamily) [73-240]
Sequence:
MQTLVLLLWTGALLGHGSSQNVPDSSQDSPAPDSTGEPVVEEDDPFFKAPVNKLAAAVSNFGYDLYRLRSDPKAILRYGLDSDLNCKIAQLPLTGSMSIIFFLPLTVTQNLTMIEESLTSEFVHDIDRELKTIQAVLTVPKLKLSYEGDVTNSLQDMKLQSLFESPDFSKITGKPVKLTQVEHRAAFEWNEEGAGTSSNPDLQPVRLTFPLDYHLNRPFIFVLRDTDTGALLFIGRILDPSST
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140678 (molecular function inhibitor activity), GO:0061134 (peptidase regulator activity), GO:0004857 (enzyme inhibitor activity), GO:0061135 (endopeptidase regulator activity), GO:0030414 (peptidase inhibitor activity), GO:0004866 (endopeptidase inhibitor activity), GO:0004867 (serine-type endopeptidase inhibitor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0042592 (homeostatic process), GO:0048871 (multicellular organismal-level homeostasis), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:0060249 (anatomical structure homeostasis), GO:1901700 (response to oxygen-containing compound), GO:0001894 (tissue homeostasis), GO:0009743 (response to carbohydrate), GO:0001895 (retina homeostasis), GO:0034284 (response to monosaccharide), GO:0009746 (response to hexose), GO:0009749 (response to glucose)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Nucleolar protein 10 (A6HP45)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR007264: H/ACA ribonucleoprotein complex, subunit Nop10 (family) [1-63]
- IPR036756: H/ACA ribonucleoprotein complex, subunit Nop10 superfamily (homologous_superfamily) [3-58]
Sequence:
MFLQYYLNEQGDRVYTLKKFDPMGQQTCSAHPARFSPDDKYSRHRITIKKRFKVLMTQQPRPVL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0043412 (macromolecule modification), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0042254 (ribosome biogenesis), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0009451 (RNA modification), GO:0000154 (rRNA modification), GO:0034470 (ncRNA processing), GO:0001522 (pseudouridine synthesis), GO:0006364 (rRNA processing), GO:0034660 (ncRNA metabolic process), GO:0016072 (rRNA metabolic process), GO:0031118 (rRNA pseudouridine synthesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:1902494 (catalytic complex), GO:0140513 (nuclear protein-containing complex), GO:0031974 (membrane-enclosed lumen), GO:0043233 (organelle lumen), GO:0005732 (sno(s)RNA-containing ribonucleoprotein complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005634 (nucleus)
Protein: Serine protease inhibitor, Kunitz type 2 (A6J9Q4)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR020901: Proteinase inhibitor I2, Kunitz, conserved site (conserved_site) [66-177]
- IPR036880: Pancreatic trypsin inhibitor Kunitz domain superfamily (homologous_superfamily) [34-185]
- IPR002223: Pancreatic trypsin inhibitor Kunitz domain (domain) [35-182]
Sequence:
MAQLCEPRRGRALLALLASLLLSGAQAASRDLDVHESCGVSKVVGKCRASIPRWWYNVTDGTCQPFVYGGCEGNGNNYPSKEECLDKCAGITENTIDGLARSSDGASALSVPRKQDSADLAGEIFNYEEYCVPKAVTGPCRAAFPRWYYDVEKNSCSSFIYGGCRGNKNSYLSQEACMQHCSGKQMYPFLTPGTKAVILVGLFIMVLILLLGSSMVFLIRMVRRKQERALRTVWSTADDKEQLVKNTCVL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140678 (molecular function inhibitor activity), GO:0061134 (peptidase regulator activity), GO:0004857 (enzyme inhibitor activity), GO:0061135 (endopeptidase regulator activity), GO:0030414 (peptidase inhibitor activity), GO:0004866 (endopeptidase inhibitor activity), GO:0004867 (serine-type endopeptidase inhibitor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0065007 (biological regulation), GO:0048523 (negative regulation of cellular process), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0070848 (response to growth factor), GO:0071495 (cellular response to endogenous stimulus), GO:0008285 (negative regulation of cell population proliferation), GO:0042127 (regulation of cell population proliferation), GO:0071772 (response to BMP), GO:2000178 (negative regulation of neural precursor cell proliferation), GO:0071363 (cellular response to growth factor stimulus), GO:2000177 (regulation of neural precursor cell proliferation), GO:0071773 (cellular response to BMP stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Procollagen, type VI, alpha 2, isoform CRA_a (A6JKC0)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR052229: Collagen VI and Biomineralization Protein PIF (family) [284-1027]
- IPR002035: von Willebrand factor, type A (domain) [52-1022]
- IPR008160: Collagen triple helix repeat (repeat) [264-475]
- IPR036465: von Willebrand factor A-like domain superfamily (homologous_superfamily) [39-1027]
Sequence:
MTTTTKMLQGSFSVLLLGGLLGVLHAQQQEAISPDISTTDRNNNCPEKADCPVNVYFVLDTSESVAMQSPTDSLLYHMQQFVPQFISQLQNEFYLEQVALSWRYGGLHFSDQVEVFSPPGSDRASFTKSLQGIRSFRRGTFTDCALANMTQQIRQHVGRGVVNFAVVITDGHVTGNPCGGIKMQAERAREEGIRLFAVAPNRNLNEQGLRDIANTPHELYRNNYATMRPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIPGPHGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGSDGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGSRGPDGYPGEAGSPGEQGDQGAKGDSGRPGRRGPPGNPGDKGSKGYRGNSGAPGSPGVKGGKGGPGPRGPKGEPGRRGDPGTKGGPGSDGPKGEKGDPGPEGPRGLAGEIGSKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGTPGEKGEPGPPGPEGGRGDFGLKGAPGRKGEKGEPADPGPPGEPGPRGPRGIPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFEAIRLDDERVNSLSSFKEAVKNLEWIAGGTWTPSALKFAYNQLIKESRRQKTRVFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHETHESENLYSIACDKPQQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPELPCQTELYVAQCTQRPVDIVFLLDGSERLGEQNFYKARRFVEEVSRRLTLARRDDDPLNARMALLQYGSQNQQQVAFPLTYNVTTIHEALERTTYLNSFSHVGTGIVHAINNVVRGARGGARRHAELSFVFLTDGVTGNDSLEESVHSMRKQNVVPTVVAVGGDVDMDVLTKISLGDRAAIFREKDFDSLAQPSFFDRFIRWIC
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005518 (collagen binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:1901700 (response to oxygen-containing compound), GO:0009743 (response to carbohydrate), GO:0034284 (response to monosaccharide), GO:0009746 (response to hexose), GO:0009749 (response to glucose)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Ribonucleotide reductase M2 B (TP53 inducible) (Predicted) (A6HR51)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR030475: Ribonucleotide reductase small subunit, acitve site (active_site) [130-146]
- IPR000358: Ribonucleotide reductase small subunit family (family) [16-351]
- IPR009078: Ferritin-like superfamily (homologous_superfamily) [25-332]
- IPR012348: Ribonucleotide reductase-like (homologous_superfamily) [5-314]
- IPR033909: Ribonucleotide reductase small subunit (family) [42-317]
Sequence:
MGDPERPEAARPEEGEQLCPETKENEVRSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKSEEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVMEIIVDAVKIEQEFLTEALPVGLIGMNCVLMKQYIEFVADRLLGELGFSKIFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0016491 (oxidoreductase activity), GO:0042802 (identical protein binding), GO:0043169 (cation binding), GO:0016725 (oxidoreductase activity, acting on CH or CH2 groups), GO:0046872 (metal ion binding), GO:0016728 (oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor), GO:0046914 (transition metal ion binding), GO:0061731 (ribonucleoside-diphosphate reductase activity), GO:0005506 (iron ion binding), GO:0004748 (ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:1901698 (response to nitrogen compound), GO:0010033 (response to organic substance), GO:0010243 (response to organonitrogen compound), GO:0014075 (response to amine)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0031967 (organelle envelope), GO:0005635 (nuclear envelope), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Histone H2A (A6J3X1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Chromosome. Nucleus
InterPro domains:
- IPR007125: Core Histone H2A/H2B/H3 domain (domain) [9-89]
- IPR032458: Histone H2A conserved site (conserved_site) [22-28]
- IPR009072: Histone-fold (homologous_superfamily) [2-126]
- IPR002119: Histone H2A (family) [3-123]
- IPR032454: Histone H2A, C-terminal domain (domain) [92-123]
Sequence:
MSGRGKTGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGHYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTSATVGPKAPAGGKKASQASQEY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003684 (damaged DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0019953 (sexual reproduction), GO:0009628 (response to abiotic stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0044237 (cellular metabolic process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0007276 (gamete generation), GO:0021987 (cerebral cortex development), GO:0104004 (cellular response to environmental stimulus), GO:0021537 (telencephalon development), GO:0060322 (head development), GO:0009314 (response to radiation), GO:0033554 (cellular response to stress), GO:0030900 (forebrain development), GO:0071214 (cellular response to abiotic stimulus), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0090398 (cellular senescence), GO:0021543 (pallium development), GO:0007283 (spermatogenesis), GO:0071478 (cellular response to radiation), GO:0007420 (brain development), GO:0007399 (nervous system development), GO:0007417 (central nervous system development), GO:0048232 (male gamete generation), GO:0010212 (response to ionizing radiation), GO:0071479 (cellular response to ionizing radiation), GO:0010332 (response to gamma radiation), GO:0071480 (cellular response to gamma radiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Rho family GTPase 2, isoform CRA_b (C6EMX5)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR005225: Small GTP-binding domain (domain) [7-129]
- IPR001806: Small GTPase (family) [3-228]
- IPR003578: Small GTPase Rho (family) [7-184]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [7-186]
Sequence:
MEGQSGRCKIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRRIELNMWDTSGSSYYDNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKVVLVGCKLDMRTDLATLRELSKQRLIPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVFHVATVASLGRGGHRQLRRTDSRRGLQRSTQLPGRPDRGNEGEIHKDRAKSCNLM
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0065008 (regulation of biological quality), GO:0023056 (positive regulation of signaling), GO:0051240 (positive regulation of multicellular organismal process), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0023051 (regulation of signaling), GO:0071840 (cellular component organization or biogenesis), GO:0051239 (regulation of multicellular organismal process), GO:0051050 (positive regulation of transport), GO:0048522 (positive regulation of cellular process), GO:1903530 (regulation of secretion by cell), GO:0051049 (regulation of transport), GO:0051047 (positive regulation of secretion), GO:0046887 (positive regulation of hormone secretion), GO:0010646 (regulation of cell communication), GO:0044057 (regulation of system process), GO:0010647 (positive regulation of cell communication), GO:0016043 (cellular component organization), GO:0051130 (positive regulation of cellular component organization), GO:0010817 (regulation of hormone levels), GO:0051128 (regulation of cellular component organization), GO:0046883 (regulation of hormone secretion), GO:1903532 (positive regulation of secretion by cell), GO:0090276 (regulation of peptide hormone secretion), GO:0090087 (regulation of peptide transport), GO:0031344 (regulation of cell projection organization), GO:0031346 (positive regulation of cell projection organization), GO:0002793 (positive regulation of peptide secretion), GO:0051046 (regulation of secretion), GO:0090277 (positive regulation of peptide hormone secretion), GO:0044060 (regulation of endocrine process), GO:0034330 (cell junction organization), GO:0002791 (regulation of peptide secretion), GO:0150115 (cell-substrate junction organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0005769 (early endosome), GO:0031982 (vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle)
Protein: RNA helicase (A6HK60)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR001650: Helicase, C-terminal domain-like (domain) [328-406]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [66-405]
- IPR011545: DEAD/DEAH-box helicase domain (domain) [118-288]
- IPR014014: RNA helicase, DEAD-box type, Q motif (domain) [94-122]
- IPR000629: ATP-dependent RNA helicase DEAD-box, conserved site (conserved_site) [246-254]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [113-316]
Sequence:
MSSYSSDRDRGRDRGFGAPRFGGSRTGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQEHPDLARRTAQEVDTYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0004386 (helicase activity), GO:0008186 (ATP-dependent activity, acting on RNA), GO:0005515 (protein binding), GO:0140098 (catalytic activity, acting on RNA), GO:0048306 (calcium-dependent protein binding), GO:0019899 (enzyme binding), GO:0005516 (calmodulin binding), GO:0003724 (RNA helicase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050792 (regulation of viral process), GO:0045069 (regulation of viral genome replication), GO:1903900 (regulation of viral life cycle)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Serine (Or cysteine) peptidase inhibitor, clade I, member 2 (A6J5Q3)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR023795: Serpin, conserved site (conserved_site) [365-375]
- IPR036186: Serpin superfamily (homologous_superfamily) [5-392]
- IPR000215: Serpin family (family) [23-392]
- IPR023796: Serpin domain (domain) [25-392]
- IPR042178: Serpin superfamily, domain 1 (homologous_superfamily) [49-341]
- IPR042185: Serpin superfamily, domain 2 (homologous_superfamily) [41-392]
Sequence:
MKKTILWSFLLFLSGSQTSRTMDQKNAEFAVDLYKAISLSNKNNVIFSPLGTTVLLGMVQLGAKGKAQQQIMQTLRMQKTSTGEEFSVLKSLFSAISKKKQEFTFNLASALYLQEGFIVKESYLHSNKEFFQSATKLVDFLDAKTSAQAISTWVESKTDGKIKNMFSEEDFGPLTRLVLVNAIYFKGDWKQKFRKEDTEMTDFSKKDGSTVKIPMMKALLRAKYGYFSESSMTYQVLELPYKADEFSLVILLPTEDVNIEEVEKQVTARHVQKWFSELHEEEVEVSLPRFKIEQKLDFKEALFSLNVTEIFSGGCDLSGITDSSELYVSRAMQKVFFEINEDGSEAAASTGINIPAIMSLTQTQFLANHPFLFIMKHIQTESILFMGKVTDPDIHTVKGRDLDSL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140678 (molecular function inhibitor activity), GO:0061134 (peptidase regulator activity), GO:0004857 (enzyme inhibitor activity), GO:0061135 (endopeptidase regulator activity), GO:0030414 (peptidase inhibitor activity), GO:0004866 (endopeptidase inhibitor activity), GO:0004867 (serine-type endopeptidase inhibitor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050794 (regulation of cellular process), GO:0030155 (regulation of cell adhesion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005615 (extracellular space), GO:0044297 (cell body), GO:0036477 (somatodendritic compartment), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0012505 (endomembrane system), GO:0005576 (extracellular region), GO:0043025 (neuronal cell body), GO:0043233 (organelle lumen), GO:0030141 (secretory granule), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0060205 (cytoplasmic vesicle lumen), GO:0031983 (vesicle lumen), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0034774 (secretory granule lumen), GO:0070013 (intracellular organelle lumen), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)
Protein: RUN domain-containing protein 3A (A6HJI8)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR047338: RUN domain-containing protein 3A, RUN domain (domain) [30-185]
- IPR004012: RUN domain (domain) [52-189]
- IPR037213: RUN domain superfamily (homologous_superfamily) [18-200]
- IPR047340: RUN domain-containing protein 3A/B (family) [5-446]
Sequence:
MEASFVQTTMALGLPSKKASSRNVIVERRNLITVCRFSVKTLLEKYTAEPIDDSSEEFVNFAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENISTARAKGRAWIRVALMEKRMSEYITTALRDNRTTRRFYDSGAIMLREEATVLTGMLIGLSAIDFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPLVTDEDSWYNKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQNQREKRELEGVILELQEQLTGLIPGDHAPLAQGSKELTTALVNQWPSLSTLSRPEGASNSKLFRRHSFMSTEPLSAEASLSSDSQRLGEGKRDEEPWGPIGKDPTPSMLGLCGSLASIPSCKSLASFKSNECLVSDSPEGSPALSPS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0140678 (molecular function inhibitor activity), GO:0060589 (nucleoside-triphosphatase regulator activity), GO:0005085 (guanyl-nucleotide exchange factor activity), GO:0030695 (GTPase regulator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023056 (positive regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0010647 (positive regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0010646 (regulation of cell communication), GO:1902533 (positive regulation of intracellular signal transduction), GO:1902531 (regulation of intracellular signal transduction), GO:0010752 (regulation of cGMP-mediated signaling)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0005886 (plasma membrane)