Protein: Vertnin (E1CHH8)
Organism: Sus scrofa (Pig)
Function: Acts as a transcription factor that regulates development of thoracic vertebrae
Subcellular location: Nucleus
InterPro domains:
- IPR010921: Trp repressor/replication initiator (homologous_superfamily) [277-308]
- IPR038822: Vertnin-like (family) [1-698]
- IPR047273: Vertnin-like, ovarian tumor domain (domain) [74-241]
Sequence:
MTSREQLVLQVLQELQEAVESEGLEGLVGAALEAKQVLSSFALPTCREGGPGPQVLEVDSVALSLYPEDAPRNMLPLVCKGEGSLLFEAASMLLWGDSGLSLELRARTVVEMLLHRHYYLQGMIDSKVMLQAVRYSLCSEESPEMTSLPSATLEAIFDADVKATCFPSSFSNVWHLYALASVLQRNIYSIYPMRNLKIRPYFNRVIRPRRCDHMPATLHIMWAGQPLTNHLFRHQYFAPVVGLEEVEAESATTSLAPTPPALAPLPPPAKTLELLSQDPGLSYSYLCERYSVTKSTFYRWRRQSQEHRQKVATRFSAKHFLQDSFHRGGVVPLQQFLQRFPEISRSTYYAWKHELLGSGTCQALGPMEELEKLTEEQVAEGLGCSSPAVSSPGMVLMQRAKLYLEHCISLNTLVPYRCFKRRFPGISRSTYYNWRRKALRRNPSFKPAPVLSVAGATQPASVGEKALLPWEGEVGEEAGKATGGGQPAPREFLPLRMPLSRWQRRLRREARKQVLSGHLPFCRFRLRYPSLSPSTFWVWKSLARGWPRSLSKLHIQAPTLGKGGIQEVEEKQEKEAGRNVTAAMAPPAGTLQMTASPGEDPGAALGGPSREGALQEGAMAQGRPMVAAAGGRDGQVLVMDMLATTKFKAQAKLFLQKRFQSKSFPSYKEFSALFPLTARSTYYMWKRALYDGLTLVDG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0048523 (negative regulation of cellular process), GO:0009892 (negative regulation of metabolic process), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0080090 (regulation of primary metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0051252 (regulation of RNA metabolic process), GO:0051253 (negative regulation of RNA metabolic process), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:0010468 (regulation of gene expression), GO:2001141 (regulation of RNA biosynthetic process), GO:1902679 (negative regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0006357 (regulation of transcription by RNA polymerase II), GO:1903507 (negative regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0045892 (negative regulation of DNA-templated transcription), GO:0000122 (negative regulation of transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000785 (chromatin), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome)