Protein: receptor protein serine/threonine kinase (A0A8M9P4Z5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Single- pass type I membrane protein
InterPro domains:
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [326-338]
- IPR001245: Serine-threonine/tyrosine-protein kinase, catalytic domain (domain) [203-488]
- IPR000719: Protein kinase domain (domain) [202-499]
- IPR003605: GS domain (domain) [172-202]
- IPR000333: Ser/Thr protein kinase, TGFB receptor (family) [27-495]
- IPR017441: Protein kinase, ATP binding site (binding_site) [208-229]
- IPR045860: Snake toxin-like superfamily (homologous_superfamily) [31-108]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [180-489]
Sequence:
MRDMKASVMLAVLFVLVYSGSYATTADHLMETSTLKNDESSLQCSCENTNLCENNSCWGRICFYTSVHERVVRGCFQTAEQCYVPAIPGVYTKCCYTHHCNANLTMPEKPVCLFSVEKPIRVILLVGVPLLVLLVIAMAACGLVLWLRTRRQYCHPVEHDTSMLKVPSGGDPTYGDIFDEFCTSGSGTGLPYLVQRTMARQISLVECVGKGRYGEVWRGTWMGESVAVKIFSSRDEQSWFRETEIYNTVQLRHENILGFIASDMTSKNSSTQLWLVTHFHELGSLYDFLQYSTLDPEGCLRMCLSIASGLVHLHTEILSTQGKPAIAHRDLKSRNILVKRNGQCCIADLGLAVIHSQSTDYLDVGTNPRVGTKRYMAPEVLDETIRVDVFESYKQTDIWALGLVLWEITRRTIVNGIVEEYRPPFFDMVPSDPSFEEMKKVVCVDQHRPSLHNRLHSHPILSAIAKIMKECWFQSPSARLTALRVRKSLSKLDQDHDYDIDKLKLDL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0065008 (regulation of biological quality), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0090130 (tissue migration), GO:0007389 (pattern specification process), GO:0006950 (response to stress), GO:0003008 (system process), GO:0035295 (tube development), GO:0003002 (regionalization), GO:0001568 (blood vessel development), GO:0034405 (response to fluid shear stress), GO:0048731 (system development), GO:0090132 (epithelium migration), GO:0009799 (specification of symmetry), GO:0003013 (circulatory system process), GO:0090066 (regulation of anatomical structure size), GO:0016477 (cell migration), GO:0035239 (tube morphogenesis), GO:0009855 (determination of bilateral symmetry), GO:0003018 (vascular process in circulatory system), GO:0010631 (epithelial cell migration), GO:0035150 (regulation of tube size), GO:0048514 (blood vessel morphogenesis), GO:0008015 (blood circulation), GO:0001944 (vasculature development), GO:0072359 (circulatory system development), GO:0009953 (dorsal/ventral pattern formation), GO:0001667 (ameboidal-type cell migration), GO:0060840 (artery development), GO:0048264 (determination of ventral identity), GO:0097746 (blood vessel diameter maintenance), GO:0048262 (determination of dorsal/ventral asymmetry), GO:0035296 (regulation of tube diameter), GO:0048844 (artery morphogenesis), GO:0043542 (endothelial cell migration), GO:0043534 (blood vessel endothelial cell migration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0043235 (receptor complex), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:0098802 (plasma membrane signaling receptor complex), GO:0098797 (plasma membrane protein complex), GO:0005886 (plasma membrane)