lokahq/bioreason-rl huggingface dataset:
Protein: Beta-galactosidase (A0A8M3AJT8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR031330: Glycoside hydrolase 35, catalytic domain (domain) [57-335]
- IPR017853: Glycoside hydrolase superfamily (homologous_superfamily) [52-338]
- IPR001944: Glycoside hydrolase, family 35 (family) [60-596]
- IPR008979: Galactose-binding-like domain superfamily (homologous_superfamily) [455-590]
- IPR048912: Beta-galactosidase 1-like , first all-beta domain (domain) [394-494]
- IPR048913: Beta-galactosidase, galactose-binding domain (domain) [519-577]
- IPR026283: Beta-galactosidase 1-like (family) [47-596]
- IPR019801: Glycoside hydrolase, family 35, conserved site (conserved_site) [161-173]
Sequence:
MFSGHCSIDLDFGPAGTANRASVSAPLLSAANLIVFDYFICKRMSEREGLRADSTHFTLAGAPFRILGGSIHYFRVPRAHWRDRLLKLKACGLNTLTTYVPWNLHEPERGVYVFQDQLDLDWLLQDKKMKLRTTYSGFTSAVNSFFDKLIPRITPLQYKKGGPIIAVQVENEYGSYAKDEQYLSVVKEALMSRGISELLMTSDNREGLKCGGVDGVLQTVNLQKLSYGDVQHLAELQPQKPLMVMEYWSGWFDVWGELHHVFSAQEMISIVRELLDRGVSINFYMFHGGSSFGFMSGAVDLGTYKPQTSSYDYDAPLTESGDYTTKYHLLRSLLSSYSKEPILEPPAVQSRRVYEPVVVTQHISLWESLQCVETSFRADDPVSMENLPANNNNGQSYGYTLYQTDIYSGGELNSRNHVRDRALVFIDRELIGVLDYRTQKVKIPQSKSERTLSLLVENCGRVNYGPALDSQQKGLVGDITLENVPLKKFTMHCLDMKPGFINRLQSRKWTSVSEKPTYPAFFRGSLVVDQPTDTFIKLPNWSKGVVFVNGQNLGRHWSVGPQKALYLPGPWLKTGENEIIVFEEFKATETIHFAENPEFGKTIDVSTQLFCTLM
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds), GO:0015925 (galactosidase activity), GO:0004565 (beta-galactosidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0030030 (cell projection organization), GO:0006996 (organelle organization), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0044782 (cilium organization), GO:0060271 (cilium assembly), GO:0120031 (plasma membrane bounded cell projection assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0097546 (ciliary base), GO:0043227 (membrane-bounded organelle), GO:0120025 (plasma membrane bounded cell projection), GO:0005929 (cilium)
Protein: CDK5 and ABL1 enzyme substrate 1 isoform X1 (A0A8M9QA24)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR012388: CDK5 and ABL1 enzyme substrate 1/2 (family) [13-500]
- IPR006671: Cyclin, N-terminal (domain) [395-482]
- IPR036915: Cyclin-like superfamily (homologous_superfamily) [345-484]
Sequence:
MASALQMKPSSLEHTRKRVIDPRRRQAALSFLSNISLDGRPVQDDGDIQAEEEEDASRTRESLVCAVGQQALAAAANQALSTARAAGFMAGTVATSAAAAAPPPPDPDGDAQLLQSAFSSPFSAVPPATRGRLQTYTQGILPVSYARQSSQNYCCLEGGQIANSALELQRSRRRLISQRSSLETLEDIEENAPLRRCRTLSGSPRPKSFKKVHFIKNIRQHDMRNGSRDVKAESGRQRHPSGGMSAKEMVIGLEGVELGADGKTVSYAQFLYPTNVLGRRNTIDSTSSFSQSRNASHRSLILARANSNQSSLDTGNELGDFREYDPNLLDDPQWPCGKHKRVLIFPSYMTTVIEYVKPSDLKKDMNETFKEKFPHIRLTLSKIRSLKREIRKLTQEEFGYEESTVAMAFVYFEKLVLQGKLNKQNRKLCAGACVLLAAKIGGDLKKHEVKLLIDKLEERFRVNRRELIAFEFPVLVALEFNLHLPEHEVMPHYRRLLQNS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0032502 (developmental process), GO:0007275 (multicellular organism development), GO:0048856 (anatomical structure development), GO:0048731 (system development), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Actin filament-associated protein 1-like 2 isoform X1 (A0A8M9QN06)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR030113: Actin-filament associated protein (family) [1-886]
- IPR001849: Pleckstrin homology domain (domain) [206-472]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [183-474]
Sequence:
MDKHKVLEQLLEQLQKFLKILDVEKLSGNAKVQKGLLMELLQSYKSSNAGGDEEYIYMNKVIVTCQTQDKTNRDHRPEANGDPSKHISVKNPPEPPPPRPCNTGREPFPLPPAPAPASMENESYYEDPQPYDPISINDFGCFAVITGLRKRVEASNGVVYAVITREDTEQLSSSYESYDEEEVTKGKSTAQHQWPSPEASIELMKDARICAFLWRKKWLGQWAKQLCVVREHRLLCYKSSKDQTPLLDISLLGCSVVYKEKQTKRKEHKLKISPLGAEAIVLGLQSKEQAEQWLKVIQEISPKNTTGSDVTDSPTLICTKGEQSERYSVASESGSSTDSHAENMENKDVKKKYGKFSNLMNIGKKKVCSLESPEKSVDTSGYLNVLVNTQWRSRWCSVKDRQLWIYSDKSKGKVAQQPLSLEGCMVLPDPSPEHLYSFRIQMDGEELAILEAKSSADMGHWLGLILSQTGTKTDPEDLSYDYVNSERISSIVNAAKTSMYLMQRRYSEPNTYTDSPPSDPQTCDDIYDDVPSTENEQEEVQEVQNGSEEGTVNAEEENGKDRVYLDLIPLRSFLHTSSGRVSPQTSSTTQTEISPSTTPHVDDQLKEPVYESSLPTSTENEVPPPVAPRVDTDPSPVPNLHVQPQKISFLGQEIQKKASPLPKTQSLPQTSAQTPQSPPTSRARAASTDRLLDRLKFSPAAGPGSVEVKLGKNRTEADVRRYTDDRDRLEREREEVKNTLATLRKDRREVKDELSSCQDPIRQASLEARLKQMEETCREAERRRVEVELSLMEVKENLRKVESGPFTLGTTVDSSLLDISVPKPAAVSSPAPNTPNNTNINTPACTNNEDSPVNSATALKNRPPSVMAASKGNVLQKAKEWEKKNTT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019904 (protein domain specific binding), GO:0017124 (SH3 domain binding), GO:0042169 (SH2 domain binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0060900 (embryonic camera-type eye formation), GO:0009887 (animal organ morphogenesis), GO:0048729 (tissue morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0009888 (tissue development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009790 (embryo development), GO:0048568 (embryonic organ development), GO:0048562 (embryonic organ morphogenesis), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0090596 (sensory organ morphogenesis), GO:0002072 (optic cup morphogenesis involved in camera-type eye development), GO:0002009 (morphogenesis of an epithelium), GO:0060429 (epithelium development), GO:0016331 (morphogenesis of embryonic epithelium), GO:0002011 (morphogenesis of an epithelial sheet), GO:0048592 (eye morphogenesis), GO:0001654 (eye development), GO:0048048 (embryonic eye morphogenesis), GO:0031076 (embryonic camera-type eye development), GO:0061386 (closure of optic fissure), GO:0150063 (visual system development), GO:0043010 (camera-type eye development), GO:0048593 (camera-type eye morphogenesis), GO:0048596 (embryonic camera-type eye morphogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: protein-tyrosine-phosphatase (A0A8M2BE31)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR029021: Protein-tyrosine phosphatase-like (homologous_superfamily) [17-356]
- IPR050561: Protein Tyrosine Phosphatase (family) [40-477]
- IPR029260: Dual specificity/tyrosine protein phosphatase, N-terminal (domain) [29-167]
- IPR000387: Tyrosine-specific protein phosphatases domain (domain) [274-336]
- IPR000340: Dual specificity phosphatase, catalytic domain (domain) [232-340]
- IPR044506: Dual-specificity phosphatase CDC14, C-terminal (domain) [176-349]
- IPR016130: Protein-tyrosine phosphatase, active site (active_site) [289-299]
- IPR003595: Protein-tyrosine phosphatase, catalytic (domain) [251-345]
- IPR020422: Dual specificity protein phosphatase domain (domain) [192-353]
Sequence:
MKRKSERRCGSRKRICASLRDRSDIQLHITDQLYFALLHQKVRSTPDRHCFCIDEELSYENFYADFGPLNLAMLYRFCCKLKKKLKSCAHAKKKIVFYTYGDRKKQANAAYLIGSYAVMHLQKTPEEAYSLLVSQNAPYLPFRDASFGACMYNLNILDCLRAVHKALQFGWLDFTQFNVEEYEHYERAENGDFNWILPGKFLAFSSPHPKSKIENGYPLHAPEAYFPYFRKHNVTTIIRLNKKMYDSKRFTDVGFKHHDLFFVDGSTPNDSIVSRFLHICENADGVIAVHCKAGLGRTGTLIGCYLMKHFRLTAAEAIAWIRICRPGSVIGPQQNFVDEMQSSLWAEGELYRQKINEQENGSAKTAVAGILSGVEDISINGTNKSTSQRKTASQNHTEEEEEDCAGLTQGDKLRALKSKRQSRASTGSISLEENTVHTKSTSKSLSSEKRKRTRASLGSNRASRRSVSRRRKTLHAMPSVRFHKPCNSISKARAPLLR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0004721 (phosphoprotein phosphatase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0016791 (phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0006996 (organelle organization), GO:0030030 (cell projection organization), GO:0022607 (cellular component assembly), GO:0044782 (cilium organization), GO:0070925 (organelle assembly), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0060271 (cilium assembly), GO:0120031 (plasma membrane bounded cell projection assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0031981 (nuclear lumen), GO:0005819 (spindle), GO:0005730 (nucleolus), GO:0005694 (chromosome), GO:0005634 (nucleus), GO:0000793 (condensed chromosome), GO:0015630 (microtubule cytoskeleton)
Protein: Beta-hexosaminidase (A0A8M2BJ34)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasmic vesicle, secretory vesicle, Cortical granule. Lysosome
InterPro domains:
- IPR029019: Beta-hexosaminidase, eukaryotic type, N-terminal (domain) [37-160]
- IPR017853: Glycoside hydrolase superfamily (homologous_superfamily) [182-538]
- IPR029018: Beta-hexosaminidase-like, domain 2 (homologous_superfamily) [33-181]
- IPR015883: Glycoside hydrolase family 20, catalytic domain (domain) [182-500]
- IPR025705: Beta-hexosaminidase (family) [11-537]
Sequence:
MLCLLKFTPLFLVVAVCHGWLFGDLFEKQKELDEISLWPLPQKYQSSAVAFKLSAASFQIVHAKQSTAGPSCSLLENAFRRYFEYMFGELKRQEKSRKKAFDSDLSELQVWITSADPECDGYPSLRTDESYSLSVDETSAVLKAANVWGALRGLETFSQLVYEDDYGVRNINKTDISDFPRFAHRGILLDSSRHFLPLKVILANLEAMAMNKFNVFHWHIVDDPSFPFMSRTFPELSQKGAYHPFTHVYTPSDVKMVIEFARMRGIRVVAEFDTPGHTQSWGNGIKDLLTPCYSGSSPSGSFGPVNPILNSSYEFMAQLFKEISTVFPDAYIHLGGDEVDFSCWKSNPDIQKFMNQQGFGTDYSKLESFYIQRLLDIVAATKKGYMVWQEVFDNGVKLKADTQIHVWKGRPQYQDEMAKVTAAGFSALLSTPWYLNRVSYGQDWVDIYKADPQNFNGTDAQKKLVIGGEACLWGEYVDATNLTPRLWPRASAVAERLWSDASVTDVGNAYTRLAQHRCRMVRRGIPAEPLFVGHCRHEYKGL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds), GO:0015929 (hexosaminidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0035239 (tube morphogenesis), GO:0048514 (blood vessel morphogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0005773 (vacuole), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0005764 (lysosome)
Protein: Period 1 isoform X4 (A0A8M9PTL7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm
InterPro domains:
- IPR048814: Period circadian protein homolog 1-3, PAS-A domain (domain) [228-351]
- IPR022728: Period circadian-like, C-terminal (domain) [1104-1267]
- IPR057310: Period circadian protein homolog PER 1-3, bHLH-like domain (domain) [142-199]
- IPR000014: PAS domain (domain) [218-470]
- IPR013655: PAS fold-3 (domain) [382-466]
- IPR035965: PAS domain superfamily (homologous_superfamily) [371-471]
- IPR050760: Period circadian regulator (family) [52-693]
Sequence:
MNNNNFQAPASCGGFADKAAIEMDEEEGQNNISPAMTDNQSLCPGLNITNESQQTHSGDTDAQSSGIDSTERENDGRLGHGTSTCSSLHGKGSATETTESKSSNGNSPSPPSSSVSFSLLSGSSEQDHSTSQASNSDQPARLQTQRELLKVLRELKIHMPAERRRKGRSSTLASLQYALSCVKQVRANQEYYHQWSVEESHGCCLDLSSFTIEELDNVTSEYTLQNTDTFSVAVSFLSGKVVYISSQAASLLRCKAERLQGALFSELLAPQDVSTFYSSTAPSRLPPWSSCAGTSSQVDCAEEKSMFCRISRGRDSNGEVKYHPFRLTPYQLTLRDSDTSQPEPCCLLIAERVHSGYEAPRIPADKRIFTTSHTPNCLFQEIDERAVPLLGYLPQDLVGKPVLVYLHPEDRLLMVAIHKKILQFAGQPFDHSPLRMRARSGEYLTIDTSWSSFINPWSRKVAFIVGRHKVRTSPLNEDVFTAPEGEEMKTMSPDVPQLNELIHRFLVQPVYGGSSQGYGSLGSSGSHEHQQGATSSSESNGHTSEDQIKPRKPMTFEQICQDMHMVKTSGQQVFIESRNRPPALKQGSLEALAKAADTAEASARDGLASLALSSPPRKELPMIYSYQQINCLDSIVRYLESFNVPGTVKRKCGSSSCTTSSTSDDDKQREGAGATQDIVMMEEPPTTPTASTSAPATSVASPIPVNPQPMPSPTAAVHEKEKEKERRSGGSAGKGLTKAVLSAHTQQEEQAFLNRFRDLSQLRMVQPSGLPPPRRCTSIPGTKGVNSSQNYPSVGNTSSRRHGRGGKRQKHQVDGNIPNNTPISASGPYRGPNPAQIRPNFPSVQQSSNSWAPSAASQTNGAPVGTSFPPSYMTMFPTSSPFSVTQMGTDPSLQTGVPRFPAQGFPSVMPPVMTFMMPNYMFPQLSNPGSQLNPANSQLNAQMNSFGQFPPPVVQMSVPMFNPAMGQFYPLGSQMNPAMPAMIPQQFYNPNYQLNFSNSPSMPAANVSTTPHGQSRSSTPQSTGPQAGERDGAGSPLFQSRCSSPLNLLQLEELPSNRTDATQQTPPPGGGATQGGVVVVQNSSNRSNTQDAKLNDHPEVSESNQDALSTSSDMLDLLLQEDSRSGTGSSGSGSGSGSFASGSNGCSTSGSGTRSSNTSKYFGSIDSSENDQNHKPASGDLGGEQFIKFVLQDPIWLLMANTDDKIMMTYQIPIKDKDSVLKEDRDALKAAQKHQPHFTEEQKKELTQVHPWIQTGCLPKAINVTSCTGCESPPDSSTLPPFDLEFHEMDLNVVLREEAKQEDKLAETAFPLSPPSSDNEQRDNQANLST
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:1901700 (response to oxygen-containing compound), GO:0010035 (response to inorganic substance), GO:0006979 (response to oxidative stress), GO:0010033 (response to organic substance), GO:0009314 (response to radiation), GO:0009416 (response to light stimulus), GO:0042542 (response to hydrogen peroxide), GO:0000302 (response to reactive oxygen species), GO:0009648 (photoperiodism)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: RNA uridylyltransferase (A0A8M9Q3V3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm
InterPro domains:
Sequence:
MADRGNRKFSPRYRRQREADEAERWRSPRGRDDMSHEHTYSPKNNRRAKASLSCSSPEGPGFGQSPSHRERVQRSSPADRRNWRDRPRDGQKHDGAQSWRDKSRFVLIDSCLTRRDVLQLCLEAEGSDCDPKESSVSLKFRCDKCKVFCEDISPALSHIRERSHRKKAKELQKLALLLSIPPPAKPHCLSVSSALESIVTEFGLNDEDLKQRQNILALIEKVLHPVLPECQFRLYGSSSTKFGFKDSDVNIDVKFPSHFQHPDILLAAQEHLSKSSLFDSVEGDFHRRMPVVVCKEKASGLICKVSAGNESACLTTAYLSEMADLEPQLVPLVICFRYWAKICCVDQMEEGGLPSYCFALMVISFLQRRKEPILPTYLESMGFPLSKLKSFSLTGVEKGHVLWVYDQTNDSSLDKDKAVKKGKAPLAFKSRSPVLLGKLWIELLRYYALEFQIPEKIISVRTNGELWRDLKDWPKKRIAIEDPFTVQRNVARTLNSQTMFDYLLHCLKTTYKYFASPSKSTAGKMSTSSRSVSVNHADSVKKSAKVSSEGLNGPRVKSSPHSAEDLEDSDCLIEQDDEEDEDSEGEDEEEDEDDDDVDLDESGCEHSGDEIFPFEREMSDDVLSDGDPEEAETVPSKPKAESTKAESTAGTQSDSESFHYVFNKRFFTDGKSPVQICGVCKSDGHLKQDCPEDFQRVELERLPPMTRDFQKILSDVCEQCYRDFAPDDVELKVREHILQDFESFLRCQVPGAKLVLFGSSKNGFGFKQSDLDICMTLEGHDTAMGLDSMAIIESLAKALRKHHGLRNILPITTAKVPIVKFYHTKTGLEGDISLYNTLCFVEVQINLLDHKQYSCVLLLVCLQIYDGKQKPVVPVDGWDVYFFKDLKNLHRHWPEYKKNRESVGELWLGLLQFYTETFDFRESVICIRRKEPLSTFKKQWTSKHLAIEDPFDLSHNLGAGLSRRMASFIMKAFINARRVFGSPVRVFPPDYSNKMEYFFDPEVLTEGKLAPNDRCCRICGKIGHFMKDCPMRKRQRRDNPDGFFSGRDMNRSSKVMTDGSPYKDTRWRQKEERCCFLCGSNSHIKRDCLLSKSIESSPNTYQRSPASDRDRVESPHQDRRKKRKAKRMILGPEAGSLSNRHSSLSTSVEKWSPFK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0140098 (catalytic activity, acting on RNA), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0050265 (RNA uridylyltransferase activity), GO:0016779 (nucleotidyltransferase activity), GO:0070569 (uridylyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0031123 (RNA 3'-end processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Prominin-1 isoform X7 (A0A8M2BI60)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell projection, microvillus membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein
InterPro domains:
- IPR008795: Prominin (family) [5-861]
Sequence:
MDMWWKVGLVLVMFWGLTSSEDREEHRESPPRTAMLRAPVETLDFGFVPSVVYETHAYYEPGPMGILFHMVHAFLYVVQPNPFPKDLIVKMVQQNMGGIKGDDYKKPENVVLLLQTIYYELGFIVLSVLGVFFVLLMPIVGLCFCVCRCCENCGGEMHQRQKKNGDCLRGFYMATLIATSVFLAVGVTVAYVANQNITSQIKSTRRLVSTNIRDLKAFANYTPAQIDYLTAQYTTAKNKVLSDLDNIGTLLGGQIHNKLESEVVPALDHALRMTAVKVESAIKAMRETKESLESVSTSLETLQEGTGRLQVSLQSERVSLSNTLNDWACSNEDVTHTCNSIRGTLNQLALSANFNGLPDVEAPLANLDAVLKTDLSNIVQKGYSSFNDTPQLVREQTKGIVSALPKVKGLLDKSGAEIIGFTKMFPVEPALQNFSKFLTDSQKNIEAYYPQIDQLDFYRWIGCVLICCLVVLVLAFNFLGLLCGSCGYDKNSTPTTRGCLSNTGGNLLMASVGFSFIFSWVLMGVVVTTFIVGGNIEKLVCEPLANRQIFKIIDTPYMVHPTKKNFLPGMLFQDPNIDLTIGSMYRDCYENNGLYSALQLETKFNFNKFLNATVFNPEIGDIFNNVNVDLQGMLLLEQEGKDNLIDFANTGIGDIDYQAYLTEVNKGVTVVDLLSYANELDAQADNLPRGALENALKGHASSIRQIHKDQVVPMEQAMKFVKARSNLNQSIRQLEKTSRELPVKVTNVLNAIEAAEYLISNNASHVVKQESDKFIKKIIGYFSQYTEWVKHSLAMEVAQCKPISNIVDSAEIVACSFIVDSVNTFWFGLGGCCVLLIPSIIMSVKLAKFYRRMDTEDVFDDGSENWS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0016043 (cellular component organization), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0022008 (neurogenesis), GO:0035845 (photoreceptor cell outer segment organization), GO:0007399 (nervous system development), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0042461 (photoreceptor cell development), GO:0046530 (photoreceptor cell differentiation), GO:0048699 (generation of neurons)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0045177 (apical part of cell), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0016324 (apical plasma membrane)
Protein: calcium/calmodulin-dependent protein kinase (A0A8M9PKD4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [131-143]
- IPR000719: Protein kinase domain (domain) [13-271]
- IPR013543: Calcium/calmodulin-dependent protein kinase II, association-domain (domain) [415-542]
- IPR017441: Protein kinase, ATP binding site (binding_site) [19-42]
- IPR032710: NTF2-like domain superfamily (homologous_superfamily) [409-539]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [9-285]
Sequence:
MATTTCTRFTDEYQLYEELGKGAFSVVRRCVKLSTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLLFDLVTGGELFEDIVAREYYSEADASHCIHQILDSVHHIHQHDIVHRDLKPENLLLASKCKNAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAQEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLVSRNFSVGSRQTTAPASVTAAAAAVAAAAGTTAGLVEQAAKTLLNKKADVKPQTNSTKNSIVTSPKGNLPSPALEAQTTVIHNAVDGIKESSDSSNATVEDEEMKARKQEIIKITEQLIEAINNGDFEAYAKICDPGLTCFEPEALGNLVEGMDFHRFYFENLLSKNSKPIHTTILNPHVHLIGEEAACIAYIRLTQYVDGQGRPRSSQSEETRVWHRRDSKWQNVHFHCSGAPAAPLQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0006950 (response to stress), GO:0009628 (response to abiotic stimulus), GO:0070482 (response to oxygen levels), GO:0001666 (response to hypoxia), GO:0036293 (response to decreased oxygen levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)