lokahq/bioreason-rl huggingface dataset:
Protein: DNA-binding protein Ikaros isoform X6 (A0A8M2B3I1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
Sequence:
MAASDGLLGVSFYWHDTKRSAKLCCLDSPSRFGLWNKSLQNVSHEHRDIAMLGWKEEVQWRGEGPRAEFQTAAAALKTCAHGAAGDSWKSFILQTQGIAEYLHRMETEEAQEMSQITGRDSPMNANEGGEDQDEAMPVPEDLSASTGLQHNNRTDKPLGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSVGKPHKCAYCGRSYKQRSSLEEHKERCHNYLQCMGLQNSIYTGENRLSELSFESGSGELMQPHVIDQAINSAISYLGAESLRPLVQTSPGSADMVVSPLYNLHKSQTAEGNGVSAKDSAAEHLLLLSKSKSASVDKDGSPSPSGQDSTDTESNNEERSAGVSGTAATGGLIYLTNHMAPGMRNGGLPGVKEEQHRQFEALRAAGMDLSIASSEGFKVLSGDGEELRAYRCIHCRVLFLDHVMYTIHMGCHGFRDPFECNLCGYRSQDRYEFSSHITRGEHRI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0001775 (cell activation), GO:0045321 (leukocyte activation), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0046649 (lymphocyte activation), GO:0030097 (hemopoiesis), GO:0042110 (T cell activation), GO:0002521 (leukocyte differentiation), GO:0030098 (lymphocyte differentiation), GO:0042113 (B cell activation), GO:1903131 (mononuclear cell differentiation), GO:0030217 (T cell differentiation), GO:0030183 (B cell differentiation), GO:0033077 (T cell differentiation in thymus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 isoform X4 (A0A8M9PJR1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR009071: High mobility group box domain (domain) [30-104]
- IPR036910: High mobility group box domain superfamily (homologous_superfamily) [26-135]
Sequence:
MSKRPPYAPAPTPAPTTNSSGITVPKPPKPPDKPLMPYMRYSRKVSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQDYLNEYEAEKIEYNDSLKAYHNSPAYLAYVNAKNRAEAALEEESRQRQSRLDKGEPYMSIQPAEDPDDYDDGFSMKHTAAARFQRNHRLISDILSEVVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEDRHQEKKRRFLESTDSFNNELKRLCGLKVEVDMEKLAAEMAAAEEAARRRAEEREREAAEQVERAAQEEQQPASAQANANTEQTSASETKDGEDKPTPMETESLAETSEGSQEAEQGTPAAGEKAAQPEPAEGATDEGTSDSTAPSESSSGPPAEHQTASDNTPEERLPTQPQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048731 (system development), GO:0003157 (endocardium development), GO:0048513 (animal organ development), GO:0007507 (heart development), GO:0072359 (circulatory system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Ferrochelatase (A0A8M9PIE9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Catalyzes the ferrous insertion into protoporphyrin IX
Subcellular location: Mitochondrion inner membrane
InterPro domains:
- IPR033659: Ferrochelatase, N-terminal (domain) [55-216]
- IPR001015: Ferrochelatase (family) [47-391]
- IPR033644: Ferrochelatase, C-terminal (domain) [221-358]
- IPR019772: Ferrochelatase, active site (active_site) [244-262]
Sequence:
MAVLGGACRLVQLVRCGSPVGLCLSSSLRRQSTATAAAFNTTATPETKESRKPKTGILMLNMGGPEKLEDVHDFLLRLFMDTDLMQLPVQNKLGPFIAKRRTPKIQEQYSKIGGGSPIKAWTTMQGEGMVKLLDEMCPDTAPHKFYIGFRYVHPLTEEAIELMEKDGVERAVAFTQYPQYSCSTTGSSLNAIYRYYSNRADRPKMRWSVIDRWPTHPLLIECFAEHVRNELDKFPVEKRDDVVILFSAHSLPLSVVNRGDPYPQEVGATVQRVMDRLGHCNPYRLVWQSKVGPMAWLGPQTDEVIKGLCQRGKRNLLLVPIAFTSDHIETLHELDIEYSQVLGEEVGVENIRRAESLNGNPLFFRALADLVQSHLQSNESCSRQLTLRCPLCVNPTCAQTKAFFSSQKL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0042592 (homeostatic process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0021700 (developmental maturation), GO:0048871 (multicellular organismal-level homeostasis), GO:0002262 (myeloid cell homeostasis), GO:0034101 (erythrocyte homeostasis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048469 (cell maturation), GO:0071695 (anatomical structure maturation), GO:0048872 (homeostasis of number of cells), GO:0043249 (erythrocyte maturation), GO:0030097 (hemopoiesis), GO:0030218 (erythrocyte differentiation), GO:0030099 (myeloid cell differentiation), GO:0061515 (myeloid cell development), GO:0048821 (erythrocyte development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: ARF GTPase-activating protein GIT2 isoform X2 (A0A8M2BCH9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR022018: ARF GTPase-activating protein GIT1, C-terminal (domain) [633-797]
- IPR013724: GIT, Spa2 homology (SHD) domain (domain) [276-370]
- IPR032352: Arf GTPase-activating protein GIT1/2, coiled-coil domain (domain) [424-488]
- IPR002110: Ankyrin repeat (repeat) [142-238]
- IPR036770: Ankyrin repeat-containing domain superfamily (homologous_superfamily) [137-252]
- IPR001164: Arf GTPase activating protein (domain) [9-134]
- IPR037278: ARFGAP/RecO-like zinc finger (homologous_superfamily) [14-129]
- IPR038508: ArfGAP domain superfamily (homologous_superfamily) [6-131]
- IPR047161: ARF GTPase-activating protein Git-like (family) [11-799]
Sequence:
MVIPTLTETRMSKRLRNSEVCADCSTSDPRWASVNRGVLICDECCSVHRSLGRHNSQVRHLSNTSWPPTQLQMVQTLYNNGANAIWEHTLLDPSSIMSSKRKPNHQDKLHPNKADFIKAKYQMLAYVHRLPCRDDDSTAAADLSKQLHSSVRTGNLETCLRLLSLGAQANYFHPEKGNTPLHIAAKAGQVCQAELLCVYGADPGAPDSSGKTPINYARQAGHQDLADRLVEIQYELTDRLAFYLCGRKPDHKSGQHFIIPQMADSSVELTEFAKAAKRKLQSLSDHLFEELAMDVYDEVDRRETDAVWLATQNHSTLVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQHGNPVPSPKDNVDVFFKSGGSRHGSESQEIDQPDYDSVASDEDTDTDLRMGKADRTKSLDSDLSDGPVSVQEFLEVKNALSASEAKIQELMKANSNLNEELRLMQKKLQSLQSENSSLRRQVSAQQPYQAPGGPDHPNPSSPSSCSSSSSSSSALKRHLSARASRPMSMYETGSGLKPFLPKGETPYPEETFPTLQPFPAYASKFDKQSSVSDGDYDNTVNESDLDDSGFGRRCRLRSSGWMGESGSIPELEDHECELDPSLPSTEDVIRKTEQITKNIQELLRAAQENKHESAPCEQRESVRRLRHSLGCFSTLVPWADKPPSPMQPLGLRAPHPANPNNPASCFVPCAERIHVAVNEMAALFPKRPRSETVRNSLRLLTSSANRLQTECKKASPLESSQASDMQLVTQQVIQCAYDIAKAAKQLVTITTKENN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0050793 (regulation of developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0009790 (embryo development), GO:0048598 (embryonic morphogenesis), GO:0016477 (cell migration), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0007369 (gastrulation), GO:0022604 (regulation of cell morphogenesis), GO:0001667 (ameboidal-type cell migration), GO:0042074 (cell migration involved in gastrulation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction), GO:0070161 (anchoring junction), GO:0005911 (cell-cell junction)
Protein: Homeobox protein Meis2 isoform X4 (A0A8M3AJB0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
- IPR008422: KN homeodomain (domain) [302-341]
- IPR032453: Homeobox protein PKNOX/Meis, N-terminal (domain) [69-182]
- IPR001356: Homeodomain (domain) [282-349]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [283-356]
- IPR050224: Three Amino acid Loop Extension (TALE) homeobox (family) [58-354]
Sequence:
MAQRYDELAHYGGMDGVGMYGDPHAPRPLPQVHHLNHGPPLHASQHYGTHAPHPNVMPTSMGSAVNDVLKRDKDQIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHMGNGWIRSDRLQNPASWRDHDDATSTHSAGTPGPSSGGLASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009790 (embryo development), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:1904888 (cranial skeletal system development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048701 (embryonic cranial skeleton morphogenesis), GO:0048703 (embryonic viscerocranium morphogenesis), GO:0048705 (skeletal system morphogenesis), GO:0048568 (embryonic organ development), GO:0001501 (skeletal system development), GO:0048562 (embryonic organ morphogenesis), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development), GO:0048704 (embryonic skeletal system morphogenesis), GO:0048706 (embryonic skeletal system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Nucleophosmin (A0A8M1NVF2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus, nucleolus. Nucleus, nucleoplasm
InterPro domains:
- IPR004301: Nucleoplasmin family (family) [9-293]
- IPR036824: Nucleoplasmin core domain superfamily (homologous_superfamily) [10-115]
- IPR032569: Nucleophosmin, C-terminal (domain) [248-295]
- IPR024057: Nucleoplasmin core domain (domain) [15-115]
Sequence:
MEDNIKDLSRPQMYLFGCSLKGDKKEHKVDLDDDEAEHQLSLKSVCLGAEAEDKFHTVETEGLTYDGKTTKITLAVLKPSVLPSLSLGGFEVTPPVSFRLQSGGGPVYISGQHFVSVKESDDEDEEEEENNTSPVKRPSNMTLAKVPQKKLKMDSDEDEDSDDDDDDDDDDDDDEEDDDKQEKPAVKSPVKSTQKTPEKKKSADKQNGSPDKKAGTSGKPQTQTPQKVKDKSAAGPSGKTPSIPSLSEVKSKLTSAAKEGKPFPKTEQKFENFARSSFKISDKQVIKDLWNFVQSLKK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0060090 (molecular adaptor activity), GO:0030674 (protein-macromolecule adaptor activity), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0042393 (histone binding), GO:0140463 (chromatin-protein adaptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0050794 (regulation of cellular process), GO:0010941 (regulation of cell death), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0030097 (hemopoiesis), GO:0043067 (regulation of programmed cell death), GO:0042981 (regulation of apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005634 (nucleus)
Protein: Protrudin (A0A8M3B4A6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell projection, growth cone membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein
InterPro domains:
- IPR017455: Zinc finger, FYVE-related (domain) [348-414]
- IPR000306: FYVE zinc finger (domain) [340-415]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [353-416]
- IPR042405: Protrudin (family) [12-414]
- IPR011011: Zinc finger, FYVE/PHD-type (homologous_superfamily) [326-413]
Sequence:
MQCSASSPQEPPQASAERPELTQLPTKDPSCADSASDPGSPKALTFDLLNMVICFKRMLIFLEPITDTLEVLRYLLGWKMPLFSLLSCVLLNILFLTLTEGSWFSLLLLAISAPAVLGFLGDRCQGASSEMALQKKKHYAVQRRDLQTVHMSKQEAMLEVKGMLKQIDDLLTQACVYAESVYKVLYWESHAVSSMFYGFLLTAVCLLYTAPVGVSLSVINSALFLWNRDFCRVLLKLKEFVHPTYVEPVEETELCDSDQANLLERTPTPTSVEDLSPGNIEEAEEAEPDDEFKDAIEESQLVLPDDEDVSSGVPEFDTVSDNGLLSRNEPIRSKVSKLTEKLRKRVPTNATGNCVQCNSAFSVLKKRRNCSNCGISFCSRCCSYKVFRSTMGATAPEAQRETVFVCSTCNTFLSTK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0032989 (cellular component morphogenesis), GO:0000902 (cell morphogenesis), GO:0016043 (cellular component organization), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0022008 (neurogenesis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0048858 (cell projection morphogenesis), GO:0030182 (neuron differentiation), GO:0032990 (cell part morphogenesis), GO:0048666 (neuron development), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0048812 (neuron projection morphogenesis), GO:0061564 (axon development), GO:0007409 (axonogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: protein-tyrosine-phosphatase (A0A8M9Q9K5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR029021: Protein-tyrosine phosphatase-like (homologous_superfamily) [17-356]
- IPR050561: Protein Tyrosine Phosphatase (family) [40-426]
- IPR029260: Dual specificity/tyrosine protein phosphatase, N-terminal (domain) [29-167]
- IPR000387: Tyrosine-specific protein phosphatases domain (domain) [274-336]
- IPR000340: Dual specificity phosphatase, catalytic domain (domain) [232-340]
- IPR044506: Dual-specificity phosphatase CDC14, C-terminal (domain) [176-349]
- IPR016130: Protein-tyrosine phosphatase, active site (active_site) [289-299]
- IPR003595: Protein-tyrosine phosphatase, catalytic (domain) [251-345]
- IPR020422: Dual specificity protein phosphatase domain (domain) [192-353]
Sequence:
MKRKSERRCGSRKRICASLRDRSDIQLHITDQLYFALLHQKVRSTPDRHCFCIDEELSYENFYADFGPLNLAMLYRFCCKLKKKLKSCAHAKKKIVFYTYGDRKKQANAAYLIGSYAVMHLQKTPEEAYSLLVSQNAPYLPFRDASFGACMYNLNILDCLRAVHKALQFGWLDFTQFNVEEYEHYERAENGDFNWILPGKFLAFSSPHPKSKIENGYPLHAPEAYFPYFRKHNVTTIIRLNKKMYDSKRFTDVGFKHHDLFFVDGSTPNDSIVSRFLHICENADGVIAVHCKAGLGRTGTLIGCYLMKHFRLTAAEAIAWIRICRPGSVIGPQQNFVDEMQSSLWAEGELYRQKINEQENGSAKTAVAGILSGVEDISINGTNKSTSQRKTASQNHTEEEEEDCAGLTQGDKLRALKSKRQSRASTGSISRVLVKCCSVLGSLWPGCCVLF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0006996 (organelle organization), GO:0030030 (cell projection organization), GO:0022607 (cellular component assembly), GO:0044782 (cilium organization), GO:0070925 (organelle assembly), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0060271 (cilium assembly), GO:0120031 (plasma membrane bounded cell projection assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005694 (chromosome), GO:0005634 (nucleus), GO:0000793 (condensed chromosome)
Protein: Nucleoporin p58/p45 isoform X1 (A0A8M2B9R7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus, nuclear pore complex
InterPro domains:
- IPR024882: Nucleoporin p58/p45/NUP49 (family) [57-597]
Sequence:
MSSFNFGTTTLGTTGAPAAAGGGGFSFGAATSTPAAGTGGFSFGGFGAQTSTPAPATTSTTSTLGFGTSLFAQKPTTGFSLSTPASAAAASTSGLSLGSLTTSTAASTGFSLGFGKPAASATPFSLTTTTASAPAATGLSLGSVLTSTVPQTSSTGFSLNLGAAAATSSAPASGFSFGSSLFSNPTLTGLGQSTLGGPLSLGGLVSTSVATTSAPAPSLGLGGVDFSTSSEKNTDKLSSTRPEDSKALKDENLPAPICQDVDNFQKFVKEQKQVQEEISRMSSKPILKVQEDIKMLRQLLSICASGLQRNSLSIDKLKLETSQELKNADIALRTQKTPPGLQHENTAPSDYFRALVEQFEVQLQQYRQQIEELENHLTTQGSGSHITPQDLSMAMQKLYQTFVALAAQLQGVHENVKTLKHQYLGYRRAFLEDSTDIFESKRVAGKKWQSSPRVTTGPAPFGSVPNAAAVAMAATLTQQQQPAPGPQAPLGASFGTPFSSGIGSSMGSSSLGAFGSGPGFGGVASGGLSFGFSSSKPSGGSLSAGFGTSNTSGFNFSNPGINASAGLTFGVSNTQTPGFGAGGPLLQLKKPPAGNKRGKR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0035295 (tube development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0061009 (common bile duct development), GO:0048732 (gland development), GO:0061008 (hepaticobiliary system development), GO:0001889 (liver development), GO:0035622 (intrahepatic bile duct development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0140513 (nuclear protein-containing complex), GO:0031975 (envelope), GO:0012505 (endomembrane system), GO:0005643 (nuclear pore), GO:0043229 (intracellular organelle), GO:0031967 (organelle envelope), GO:0005635 (nuclear envelope), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Pre-B-cell leukemia homeobox 1a isoform X1 (A0A8M6Z2J2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
- IPR008422: KN homeodomain (domain) [248-286]
- IPR017970: Homeobox, conserved site (conserved_site) [265-288]
- IPR005542: PBX, PBC domain (domain) [37-231]
- IPR001356: Homeodomain (domain) [227-294]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [233-299]
- IPR050224: Three Amino acid Loop Extension (TALE) homeobox (family) [37-318]
Sequence:
MDDQPRLMHSSHGVGMAGHPGLAQHMQDGTGGADDEGRKQDIGNILQQIMTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPPDAQLMRLDNMLLAEGVSGPEKGGGSAAAAAAAAAAGGVGSDNSAEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKFQEEANMYAARTAANATSVSTHGSQANSPSTPNSAGSAGSFNMNSGDLFMSVQSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSESLAASQIYSPQGINANGGWQDAPTPSSVTSPTEGPGSVHSDTSN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009887 (animal organ morphogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0030097 (hemopoiesis), GO:0002521 (leukocyte differentiation), GO:0030099 (myeloid cell differentiation), GO:0048794 (swim bladder development), GO:0001944 (vasculature development), GO:0072359 (circulatory system development), GO:0002573 (myeloid leukocyte differentiation), GO:0060216 (definitive hemopoiesis), GO:0030851 (granulocyte differentiation), GO:0030223 (neutrophil differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005667 (transcription regulator complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)