lokahq/bioreason-rl huggingface dataset:
Protein: Synuclein, gamma b (Breast cancer-specific protein 1) isoform X1 (A0A8M9PWC8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR001058: Synuclein (family) [1-103]
Sequence:
MDVLMKGFSMAKEGVVAAAEKTKAGVEEAALKTKEGVMYVGNKTKEGMVSGVNTVVQKTTDQANIVGETAVGGANVAGQNTVEGLENVAASTGMVNPDEALYEGDFSHGGMEGGEGGEGY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0007610 (behavior), GO:0030537 (larval behavior), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0007626 (locomotory behavior), GO:0022008 (neurogenesis), GO:0007399 (nervous system development), GO:0030182 (neuron differentiation), GO:0008345 (larval locomotory behavior), GO:0071542 (dopaminergic neuron differentiation), GO:0048699 (generation of neurons)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0150034 (distal axon), GO:0044306 (neuron projection terminus), GO:0042995 (cell projection), GO:0030054 (cell junction), GO:0044297 (cell body), GO:0098793 (presynapse), GO:0036477 (somatodendritic compartment), GO:0005737 (cytoplasm), GO:0043025 (neuronal cell body), GO:0043679 (axon terminus), GO:0120025 (plasma membrane bounded cell projection), GO:0045202 (synapse), GO:0043195 (terminal bouton), GO:0043005 (neuron projection), GO:0030424 (axon)
Protein: Homeobox protein Meis2 isoform X3 (A0A8M3ARP6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
- IPR008422: KN homeodomain (domain) [301-340]
- IPR032453: Homeobox protein PKNOX/Meis, N-terminal (domain) [69-182]
- IPR001356: Homeodomain (domain) [281-348]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [282-353]
- IPR050224: Three Amino acid Loop Extension (TALE) homeobox (family) [58-353]
Sequence:
MAQRYDELAHYGGMDGVGMYGDPHAPRPLPQVHHLNHGPPLHASQHYGTHAPHPNVMPTSMGSAVNDVLKRDKDQIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHMGNGWIRSDRLQNPASWRDHDDATSTHSAGTPGPSSGGLASQSGDNSSEQDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009790 (embryo development), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:1904888 (cranial skeletal system development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048701 (embryonic cranial skeleton morphogenesis), GO:0048703 (embryonic viscerocranium morphogenesis), GO:0048705 (skeletal system morphogenesis), GO:0048568 (embryonic organ development), GO:0001501 (skeletal system development), GO:0048562 (embryonic organ morphogenesis), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development), GO:0048704 (embryonic skeletal system morphogenesis), GO:0048706 (embryonic skeletal system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Beta-2 adrenergic receptor (A0A8M9PI29)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein
InterPro domains:
Sequence:
MEGDNTLITENTSLYMNISAGLNASSPVSLSVSEYSDAEVVLISILIGILVLVIVFGNALVISAIVRFQRLQTVTNYFISSLACADLVMGLMVVPFGACYILLNTWHFGNFFCEFWTATDVLCVTASIETLCVIALDRYIAIMWPLRYQSMLTKRKACGMVIGVWAVAALISFLPIHMEWWVSDEPEALSCLEEPTCCDFNTNAAYAVTSSIISFYIPLVIMAFVYSRVFQEARRQLQKIDRIEGRIRTQSLSTQEGNEIKNRRTKFCMKDHKALKTLGIIMGTFTLCWLPFFVLNVVAAIWKMDNIMLPFRILNWIGYANSAFNPLIYCRSPEFRCAFQEILCWRPSHLPSTRSKKGYLYSGHSWKVHTKTTRPREPSPACETEIGAECLTAGTKNKNGNYNKTVTSI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0004930 (G protein-coupled receptor activity), GO:0008227 (G protein-coupled amine receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0065008 (regulation of biological quality), GO:0051239 (regulation of multicellular organismal process), GO:0044057 (regulation of system process), GO:0002027 (regulation of heart rate), GO:1903522 (regulation of blood circulation), GO:0008016 (regulation of heart contraction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: CDK5 and ABL1 enzyme substrate 1 isoform X2 (A0A8M2BB65)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR012388: CDK5 and ABL1 enzyme substrate 1/2 (family) [13-499]
- IPR006671: Cyclin, N-terminal (domain) [394-481]
- IPR036915: Cyclin-like superfamily (homologous_superfamily) [344-483]
Sequence:
MASALQMKPSSLEHTRKRVIDPRRRQAALSFLSNISLDGRPVQDDGDIQAEEEEDASRTRESLVCAVGQQALAAAANQALSTARAAGFMAGTVATSAAAAAPPPPDPDGDAQLLQSAFSSPFSAVPPATRGRLQTYTQGILPVSYARQSSQNYCCLEGGQIANSALELQRSRRRLISQRSSLETLEDIEENAPLRRCRTLSGSPRPKSFKKVHFIKNIRQHDMRNGRDVKAESGRQRHPSGGMSAKEMVIGLEGVELGADGKTVSYAQFLYPTNVLGRRNTIDSTSSFSQSRNASHRSLILARANSNQSSLDTGNELGDFREYDPNLLDDPQWPCGKHKRVLIFPSYMTTVIEYVKPSDLKKDMNETFKEKFPHIRLTLSKIRSLKREIRKLTQEEFGYEESTVAMAFVYFEKLVLQGKLNKQNRKLCAGACVLLAAKIGGDLKKHEVKLLIDKLEERFRVNRRELIAFEFPVLVALEFNLHLPEHEVMPHYRRLLQNS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0032502 (developmental process), GO:0007275 (multicellular organism development), GO:0048856 (anatomical structure development), GO:0048731 (system development), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Transient receptor potential cation channel subfamily A member 1 isoform X2 (A0A8M9PU11)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
Sequence:
MQFGKELVRRNSFYKCVINEDETEESADVFELAFKGKASAIDRLIQKGPEHLSLRDENGASLLHYASAGGNLDIIRLIVSIVGPEVLNVQDEQGRTPLHWAVEQDQQQSCAVLLDLGADPNILNNALMGPLHLAVTKQYNHLAEVLLSCDKTNSNLEGDLGNTPVMLACSNNNCQALQILIKRGAKMCIQNKLGHYPIHTVAFAGAKEAMEMVLKIGEELGVSSTLHINYLDKSKSTPLHLAVRGGNIEVIKLCILKGAKVEQHQSGKCTALHFACSQGSLEAVKIMLSSYNRTEDIVNIRDGANRTPLHRATLFDHVELAEYLISKGAEIDSIDCKGLSPLLLASSCSAWKTVAYLLSIGADFKIKEKTGRNFLHFVILQPKGLKNLPETVLQSTAVKEMLSDEDVEGCTPLHYACKLGIHDSVKNMLGLNICLGQKSREKKSALHFAAEYGRINTCHRLLETLTDSKMLNDWDEKGLTPLHLASRAGHAQVVDLLLRKGALFQSDYKGWTCLHHAAAEGYTQTMKILLAANVKLLDEKNEDGNTALHIAAQAGHVSAVLLLLDRGAEIALNDADNSFLHEAVRNERREVVNATIEHERCDESMTSFKAKSRCVVLDIIEFLPESFQHLLDQCITESDHDANSQDYHIMYNFQWLQAPIQLKKYAKTDKTKAFQPLAALNAMVRYNRLELLIHPLSRKYLEMKWTAYGSKVHFLNLAIYLLGLLPLTYLILNLRPSQDFSKGNGTSVIMVPVSFSEQQYLISVCIIMVIVMNVYSICKEVVQLAQQRVNYFTDFSNPADWSAAISALVFVVPMCCSVEATWQWEAGAYAILTSWIGFLLYFQRFERIGIYVVMFNGIVRTLVCIMVLFVFLLLAFGLAFYALMLHRPEFSSISLALAQTFVMTVGELNYQSTFLNSYEEGHMAFPAITYLVFVFFVLLMPILLMNLMIGLAVGDIAEVQRNAELKRIAMQIFTLPLRRNYLTGS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0051234 (establishment of localization), GO:0042221 (response to chemical), GO:0051606 (detection of stimulus), GO:0055085 (transmembrane transport), GO:0003008 (system process), GO:0007610 (behavior), GO:0050877 (nervous system process), GO:0034220 (monoatomic ion transmembrane transport), GO:0009593 (detection of chemical stimulus), GO:0050906 (detection of stimulus involved in sensory perception), GO:0007635 (chemosensory behavior), GO:0006810 (transport), GO:0062149 (detection of stimulus involved in sensory perception of pain), GO:0050907 (detection of chemical stimulus involved in sensory perception), GO:0006811 (monoatomic ion transport), GO:0007600 (sensory perception), GO:0007606 (sensory perception of chemical stimulus), GO:0019233 (sensory perception of pain)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Estrogen-related receptor gamma isoform X6 (A0A8M9P8U5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
Sequence:
MDSVELSLPECFSLHSDQQLLCRMSNKDRHIESSCPSYIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPTLYGPTGALGPSGTGAKRYEDCSSTITEDSQIKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGLATGNIEYSCPATNECEITKRRRKSCQACRFMKCLTVGMMREGVRLDRVRGGRQKYKRRIDAENSPYLNPQLALPPKKPFPFGCLADNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVNIGWAKHIPGFSTLSLADQMSLLQSAWMEILILRVVYRSLSFEDKLVYAEDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHVEDPRRAGKLLMTLPLLRQTSTKAVQHFYSIKQDGKVPMHKLFLELLEAKV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Kinase (A0A8M9QA58)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
Sequence:
MLLDNDSYSKERSRHARKDKDKSVKREEELEWLKQAEVFYYSLERSNAAGPQLKHNPWSLKCHQQHLQRMKENAKHRNQYKFILLENLTWSYAVPCVLDLKMGTRQHGDDASEEKKAMQIRKCQQSTSASIGVRLCGMQVYHPATGQLMFMNKYHGRKLTLSGFKEAIFQFFHDGRRLRRELLSPVLRRLRDMQAALEACESYRFYSSSLLIIYDGDPPRTRHSAEDGLSEEEEEEDDDDDEEEEEEEEEEGAAFGFPHGAGAASSSSGACGGGSSTSSSSVVRRMARSDSGPAVDVRMIDFAHTTCRHYGEDSVVHEGQDSGYIFGLENLITIISQLEDHSTD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0023056 (positive regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0010647 (positive regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0035556 (intracellular signal transduction), GO:0010646 (regulation of cell communication), GO:0045880 (positive regulation of smoothened signaling pathway), GO:0007188 (adenylate cyclase-modulating G protein-coupled receptor signaling pathway), GO:0008589 (regulation of smoothened signaling pathway), GO:0007189 (adenylate cyclase-activating G protein-coupled receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Solute carrier family 22 member 7 (A0A8M9PVC4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
Sequence:
MRFEDLLSELNGFGRFQKMVLCINFLGRFSLGCHFLLGNFIAAIPSHHCNISSLDVDGVFENLSQEERLTVGVPAQEDGTPASCHMFSHPQFQLLINSSSSSDLPVVECQNGWHFDNSTFISTLATQWDLVCDKRALGKLTTTIFFLGVMFGAAAFGSLSAMFGRKPMLLVSYILGMGFGLCSVLSSSLLMFAVLRFFSGFTITGSVIISTVLNVEWVSIEHRKLVGVIDSLAWTFGFMGFPVIAYFIRDWRWLTVAISLPNVISIITWWWVPESARWLIVNGKADKAHYYLKKCAAMNHKKEVTARIKPEDLSKIIVTDRGSRKYSYLDLVRTPKMRRLSLLTGITWFSVATVAYGISFNITGFGLNMYLTQFVYGAIEIPAKFCIYYLLDKFGRHVTQAGSLLFVGISFIINIFIPKEKTVIRTVIAVLGKGCSATSFGTVILYTSELYPTVVRQNGMGYTSFIARFGVSVAPLILLSNDVWSYFSQVILCFLALSAAFVAYQLPETSGKCLPETIDDIEGIRKDKNGLLLQDRKMEEKDNMEKLKDNLIVQNT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0008514 (organic anion transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0071705 (nitrogen compound transport), GO:0015711 (organic anion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: mitogen-activated protein kinase kinase (A0A8M3BB07)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [229-241]
- IPR000719: Protein kinase domain (domain) [116-369]
- IPR053793: PB1-like domain (domain) [1-58]
- IPR017441: Protein kinase, ATP binding site (binding_site) [122-145]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [98-388]
Sequence:
MPEATVTAFEYEDEVGDRITVRSDDELKAMLSYYCNTVMEQRFNGLLPEPLQIFPRAGKTPGIRNIHGLKVNTRPESSSGRSSSAADSRSSDSSLKKSSAELKKILTNGQINEHDLQYQEQLGHGNGGTVYKAYHLLGKRIVAVKVIPLDITVELQKQIMSELEILYKCDSPYIIKFYSAFFVENRISICTEFMDGGSLDVYWRIPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSVGISFMELALGSFPYPQIQKNQGSLMPLQLLQCIVDEDPPVLPVGQFSEKFVHFITQCMRKLPKERPAPNNLMDHPFIVQYNDGNTEVVSMWVCRSLEDRKAQQPQRLM
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004712 (protein serine/threonine/tyrosine kinase activity), GO:0016301 (kinase activity), GO:0004708 (MAP kinase kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: B-cell lymphoma/leukemia 10 isoform X2 (A0A8M9P7U3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR011029: Death-like domain superfamily (homologous_superfamily) [1-104]
- IPR001315: CARD domain (domain) [2-76]
- IPR033238: B-cell lymphoma/leukemia 10/E10 (family) [8-231]
- IPR042143: BCL10, CARD domain (domain) [6-89]
Sequence:
MMIRSSLKAIERLRPYLVDKIIADRHFDYLRSKKILTREDTEEISCRTTRGKRTSKLLDILAENPRGLDMLIESIKWGRTLNFIIARITDEVQRVKNERLEALKAGSNSAYPTTKGATNDFSKMDSDYDKYSTMCLHPEGEASSSSSVATGSFNLRYSSTRGNEALMVSGGSGTMNVSSTSSILPKPGDPGAPALPEEMENDEQDMDGGVCKSAGSSGDANFQPLRSRSLSP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0065009 (regulation of molecular function), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0044093 (positive regulation of molecular function), GO:0080090 (regulation of primary metabolic process), GO:0051090 (regulation of DNA-binding transcription factor activity), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0051091 (positive regulation of DNA-binding transcription factor activity), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0051092 (positive regulation of NF-kappaB transcription factor activity), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure), GO:0140535 (intracellular protein-containing complex)
Protein: Structure-specific endonuclease subunit SLX4 (A0A8M1RN23)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR018574: Structure-specific endonuclease subunit Slx4 (family) [1631-1684]
- IPR011333: SKP1/BTB/POZ domain superfamily (homologous_superfamily) [530-662]
- IPR013087: Zinc finger C2H2-type (domain) [206-236]
- IPR000210: BTB/POZ domain (domain) [550-661]
Sequence:
MDDSDQDFKDLCSRLLKRVRRKGPAESGDEKRSATKDEEPSSPSSGRNPPKRRKRTKDAVKTQLNGRSQTAVSAGAPQADSGVSATGKVKDAVIRRMQQFKRASPERLLHAETDGNCDAPDGVQHTEDVSGDEALALRLQQELDREARAAAGDVEDGGLFFCQLCQKDLSSMSPSLRTQHINRCLDASESSAPSTSHHSQPRPRVPECPICGKSFKSEKSRSAHLKRCSSDMGVKPNDLLQALRRQAAETESDRNADQTQQVGGAVRRDGVPVKKKSRRKGQKLDEDTMMALALSRSLLEQEVEKKRELEEQREILAQISSPPAATAPVLKWKPGAGKGRGKRRKGASPVQPPLLLIQDPQIALNRLQERVSSLLLCSRPPSPPTPTLSPSSLPLQPHAPLWDKSALHRGRQNSVSEFYTSELSSFIQPWVAPVKENDKPLEATPVKSTPGLLQDKPSDQSPTQNRTTRPLTPCSDTPGTQALQDLMELAEEGMTLTQYGYTAYTAAVGTSDKDNPLNELPSSGSAPEATDRKTDKTVYISKLASDLSSMVNNPQLSDVQLQVDSGDVFFAHSFMLYTRCPLLANMVHDSGFGVQEEGLPVARRVLFGDVLGEAVLAFLQYLYTAHCPLTHTLIPHVQELADRFGLTELQQQCEEYSGSTDENASKGMFQAPEPHLRDQEEHKFAESNFLELLQSMWQHEDSEEENEFNETSGEKRVMEEVQERDGEKEDRVDEEELDEIYEFAATQRKTETMLETATETEDDEGDANTSPGNEMMKDEEIEKGESESLQEKSAGSCHSNSRGVDGTESAMVTSPTETPNLETARVCLMPDLDAGTHENKDPDASLDKSYDRLFSQSIGEYRELSQAPASCSQKQHYKASHTLQRNTPAPFRPSCVSEVIDLSVSPPLSSGMSGETSFPMPGVSPVPYKDEDTCLRKDILSCPGIKDPPSPPKSHSKQVELIVLSDDSNEGMDVDGKHNTSTTKCALTPKSPIKSPPEPPHMVKSCALQVKPTETGPQGHAGKHVNTSKQVTIDTETKSDSSEHCSPGVANESVFDGSAEVSWLIPATPVPSTRCSSAQTCVTMRRTQLFPKPCSASSSSSSSSVLDSLKPATFASSSSKCSKEKQAPLSELLQSGQSSSKEHTSTEMDHSPGFQRPLQHLRLSQVVSDVSRASTIMGHLAQGVPQPSSSTPVHSVGSLQRKILFDSPVDREYEVPLRDSRGLSSSFNCQKKVESFQLNSPSPCKTPEKSQHECFKPSHQESSPERSRESGNNGIEQMKVGEESLNQSVEEVVDISRKSLSDMDDPWRRAREENPKQSVEEVVHIADNSLCNIEEKVEEENPNQSVEEVVEMAGSSFCQMDEPPIAFDDSWGLDGGIGSQKPHFSLRLDSSEGTLSSPGLESKGQMTSLQIKSPVASGAHNKTPDASPPSFNPSLPDPDMWDDWEEEGEEVPLPLSQRLAAPSDKRVAELKTPVAPRKRNNGPLVPITPMPGFSDMETPELKNRLNRFGVRPLPKKQMVLKLKEIHQYTHQLQSSESEDETSGPRRPPIASSSKSLSFKQPTAPPAVSPVKLPPREEEETLSASQNSNTSSTAESERSNPELCLSEDEDSDTEGITASQAVVREKDKLLAVRQFILSDPELYSRVLQYQPLPLAELRASLRAAGIRLAAAKLLDFLDSQCITFSTAKQGKSTTTRRKRRVKTTTAGRGRKKTTRPNGGVA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0035295 (tube development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0061009 (common bile duct development), GO:0061008 (hepaticobiliary system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)