lokahq/bioreason-rl huggingface dataset:
Protein: Nucleoporin p54 isoform X5 (A0A8M9P371)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR040985: Nup54, C-terminal interacting domain (domain) [503-541]
- IPR024864: Nucleoporin Nup54/Nup57/Nup44 (family) [1-548]
- IPR025712: Nucleoporin Nup54, alpha-helical domain (domain) [350-488]
Sequence:
MAFNFGGASGSASLTGTGFGAPTTTSASTGFGFGTGFGPLVCSAGPGPAPSAAAVSFGGFGLGPAAPVFSFGSGLGGAAGAFGGFGSTTTSAGTGSSFSFSTPANTGSSLFNTQSKGFGFSSAPAPASGFTGALGGGALGFGGFGALQNTQQGGVFGQQAPPPCSQLFNTASALSAPAVLSDERDSILARWNQLQAFWGIGRGYYCSTTPPVEFSQENPFCRFKAVGYSCVPDVRDEDGLLALALGKREADVRLQQQQLVESLHKLLGGAHTLSVNVEGVRALPDDQTEVIIYVVERSPNGSSKRVPASTLYNFLEQVNIKTQLQQLSVIMTVSRTALSPAQLKQLLQNPPAGVDPIIWEQAKVDNPDPEKLIPVPMVGFRELLRRLKIQEQMTKQHQTRVDIISTDISELQRNQATTAAKITQYKRKLMDLSHRVLQVLIRQEVQRKSGYAVQLDEEHLRVQLETIQSELNAPTQFKGRLNELMSQIRMQNHFGAVRAEERYRVDADLLREIRQHLKHQQEGLSHLISVIKDDLDDIKTIEDGLHDSVHTRSSKLS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0007389 (pattern specification process), GO:0035295 (tube development), GO:0048513 (animal organ development), GO:0003002 (regionalization), GO:0048731 (system development), GO:0048732 (gland development), GO:0009953 (dorsal/ventral pattern formation), GO:0035272 (exocrine system development), GO:0055123 (digestive system development), GO:0048565 (digestive tract development), GO:0061008 (hepaticobiliary system development), GO:0072359 (circulatory system development), GO:0031016 (pancreas development), GO:0007507 (heart development), GO:0031017 (exocrine pancreas development), GO:0001889 (liver development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0140513 (nuclear protein-containing complex), GO:0031975 (envelope), GO:0012505 (endomembrane system), GO:0005643 (nuclear pore), GO:0043229 (intracellular organelle), GO:0031967 (organelle envelope), GO:0005635 (nuclear envelope), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Neurotrimin isoform X2 (A0A8M9PTM6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor. Membrane; Lipid-anchor, GPI-anchor
InterPro domains:
Sequence:
MKMVVCGCWRRCVVMGLRLLFLLPAGLPVRSQGESQSDNKQMDNITIRQGETLFLSCSQGDFVTHTAWLNRSSILYAGEDKWSVDPRVSLVTLSQEEFTIKIEDVDVTDEGQYICAVQTSSRPRTTSVHIIVQVPPKIVNLSRDLVVNEGSNVTLMCLANGKPEPAIVWRMKSPSDDSLSSDSEVLDIPFISRYRAGVYECTAANDIAVDTQTVELTVNYAPSVSDGRDVGVTLGQRGVLQCEADAVPEADFEWYRDDRRIFNGLDGIEIEAAGALSRLTFFNVSEADYGNYTCVAINKLGSANTSFVLYVLEMTSSDLEQTPLQNDLWEGPGAVQDGNSGTSTVFNPFCLLIAILQLLLKF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0008037 (cell recognition), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0016043 (cellular component organization), GO:0008038 (neuron recognition), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0008039 (synaptic target recognition), GO:0022008 (neurogenesis), GO:0007399 (nervous system development), GO:0034330 (cell junction organization), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0050808 (synapse organization), GO:0048699 (generation of neurons)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062023 (collagen-containing extracellular matrix)
Protein: Transcription factor MafG (A0A8M2BGQ2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
Sequence:
MKPRDQTKSYDVWLQRERKRINTVTNSPKTATNSRRSALSPPVTVTAARDALDLRGLAAVPRGMTTTNKGNKALKVKREPGENGTSLTDDELVSMSVRELNQHLRGLSKEEILQLKQRRRTLKNRGYAASCRVKRVTQKEELERQKAELQQEVEKLASENASMKVELDALRSKYEALQSFARTVARGPVVPVSTAAVPVSPRGPLASVIGPLIPGKVGATSVITIVKSKTDARS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048522 (positive regulation of cellular process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009891 (positive regulation of biosynthetic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0010468 (regulation of gene expression), GO:1902680 (positive regulation of RNA biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0045893 (positive regulation of DNA-templated transcription), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0005667 (transcription regulator complex)
Protein: Cytokine receptor family member b1 isoform X1 (A0A8M9QJT3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [32-120]
- IPR050650: Type II Cytokine and Tissue Factor Receptors (family) [41-299]
- IPR015373: Interferon/interleukin receptor domain (domain) [66-113]
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [63-120]
Sequence:
MIGYQNEDIIIIHWPSFSHSSLLYSDLCNPCSCQLYNMVSQLQTHFTLELWGKFSSTERFQFTKVREILRSQEPSKQYVLENLQPGVQYCVKVLPQINSNQNTQPSSWQCEYTSKEEAQRVLYFMSWLLGATLSGSCVMMLAWILVYTGFLCKPKNPPLKSLSNIVPATYLIPEQTLSESLSLTEVQLIHLSYDTTENNSQLKNPEKREYEGSVLKSDTEDEEDSNDEDEVKCVYMSCEIDDISCQNNSTKKDIVSALPFNKSSIVCYTKEPAMEKIQYDDLKSEKELLSELFEEGHGHLEVTNTQLKTEGNEKGSTNTPGNINLFSVTVRTFGAEDDLDKEDVYKPLLPKLFVKTDKWTEELLPVSNKIQISIPIETGMKTDDLIHLDSQNDLVHVCSLAHNVETNPDTTMSAYMMNHIGKMHDQNKDLLEETNCDTSYITR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0140375 (immune receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0004896 (cytokine receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0048583 (regulation of response to stimulus), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0002682 (regulation of immune system process), GO:0006950 (response to stress), GO:0002253 (activation of immune response), GO:0048584 (positive regulation of response to stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0002684 (positive regulation of immune system process), GO:0050794 (regulation of cellular process), GO:0006952 (defense response), GO:0002764 (immune response-regulating signaling pathway), GO:0050778 (positive regulation of immune response), GO:0050776 (regulation of immune response), GO:0043207 (response to external biotic stimulus), GO:0002757 (immune response-activating signaling pathway), GO:0009615 (response to virus), GO:0098542 (defense response to other organism), GO:0140546 (defense response to symbiont), GO:0051607 (defense response to virus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Lysine (K)-specific demethylase 2B isoform X3 (A0A8M3AK71)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR041070: Jumonji, helical domain (domain) [327-369]
- IPR002857: Zinc finger, CXXC-type (domain) [523-569]
- IPR001810: F-box domain (domain) [1003-1042]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [1001-1264]
- IPR050690: JHDM1 Histone Demethylase (family) [35-1249]
- IPR019787: Zinc finger, PHD-finger (domain) [573-632]
- IPR001965: Zinc finger, PHD-type (domain) [578-630]
- IPR006553: Leucine-rich repeat, cysteine-containing subtype (repeat) [1034-1246]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [565-634]
- IPR003347: JmjC domain (domain) [171-339]
- IPR011011: Zinc finger, FYVE/PHD-type (homologous_superfamily) [576-634]
Sequence:
MENGQEVLTLVDGGMLLMRRRGRKRKSQQGDEDVTLKRSGTRRRYQDDGISDDEIDGRRTFDLEEKLHSSFFSSDRVKRMEGKDFSYEYVQRHGLRDPIIFEKPEGLGIKMPDPDFTVNDVKLFVGSRRIVDVMDVATQKGTEMSMAQWRRYYETPPSQREKLYNVISLEFSHTKLETLVKRPSTVDMIDWVDNMWPRHLKERQRDSTNSIMEMQYPKVQKYCLMSVQGCYTDFHIDFGGTSVWYHIHKGCKVFWLIPPTPQNLELYENWVLSGKQGDIFLGDRATDCQRIELKQGYTFIIPSGWIHAVYTPVDTLVFGGNFLHSFNVPMQLDISGIEDRTRVPVKFRYPFFFEMCWYVLERYLYSLTNKSHLIPEFQKHSLGIGLKRENSEVLNGHAKEERDEMDAPSPPSAPGLKTHLTAFELEGLWRLVGKLESLPSNKKCVPSGIHNAAALLLDIRALLKEHANDIPKLSYTGRPIVRWPKRPPWYQPPPPPPPVMRPKLATTPIVPRPVKPASNMSVLRRRRVRCKRCEACLRTECGDCNFCRDMKKFGGPGKLKQTCVLRQCLAPGLPLSAVCELCGEGNQETSEELMECSNCAQIAHPSCLKTSGEGVVNKDLPSCWECPKCVLGKDTDSEIKLDGGKSHKRKSSSLDPRVAKIYRRHGMEHDDDSGSDDDGDGGRMSSVRSSVSSSRRGYGASRRGVWRGSSQRGPRGGGSLSSSSLKMRRGLGARGERGGRVRLRGGSQMRRRRYETDDDDDDDDDDDDDDDDDDDEDEDDEDDSEEDRHVSRSEKEHRSRRRRRRGDDYDDDEDEDDDDEEDSEEQDYEGEDDEMEDLDDGGDEDDEDGENQSDSDPDPPVLLVSDLNDDLLNDSYLTVTLHRPPKAKRDPGSIVPKLEAAMSPRTGGSSGFMQRKTLPKARPKTSSSTPAGNGLSQAKSGRPTRRSSNQDGRERDTASPSSMSSRSSVSPPPPPPAVTSSSPSLLSHPSFRDAGNELGCEKDIWVSVFRYLDRTDLAVCMRVCKAWFKWCCDKRLWTRIDLSRCRALSPQAVTAIIKLQPVTLDLSWTPVSKKQLAWLIHHLPSLKDLIMSGCSSLCVSALSSPSCPSLRTLDLCWAVGVKDSQIKDLIVQPGSESRSRLRSLVSLRLSGLELSDAVIKTMVRHMPSLRQLDLSYCQGLTDQSINLLTATGCNTRNTLRQLNLSGCNKLSDGCLSYMKRLSALALLDLRGCKNVTRHGCENFISDLSYCTVFCLTEDKLIQRVS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0000003 (reproduction), GO:0032502 (developmental process), GO:0022414 (reproductive process), GO:0003006 (developmental process involved in reproduction), GO:0007530 (sex determination)
Biological Process (BP): GO:0008150 (biological process), GO:0000003 (reproduction), GO:0032502 (developmental process), GO:0022414 (reproductive process), GO:0003006 (developmental process involved in reproduction), GO:0007530 (sex determination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0140513 (nuclear protein-containing complex), GO:0000785 (chromatin), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome), GO:0005634 (nucleus)
Protein: Anion exchange protein (A0A8M2B229)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane; Multi-pass membrane protein. Membrane; Multi- pass membrane protein
InterPro domains:
- IPR016152: Phosphotransferase/anion transporter (homologous_superfamily) [2-264]
- IPR002977: Anion exchange protein 1 (family) [234-758]
- IPR001717: Anion exchange protein (family) [95-681]
- IPR018241: Anion exchange, conserved site (conserved_site) [292-453]
- IPR003020: Bicarbonate transporter, eukaryotic (family) [2-844]
- IPR011531: Bicarbonate transporter-like, transmembrane domain (domain) [291-823]
- IPR013769: Band 3 cytoplasmic domain (domain) [107-237]
Sequence:
MEMNESAKSPNQQSYWQEMGRWAGYEETYDVEAGRWSPSHISYLTFKSLVQIRRTMNTGVMMLDREEKTLSSIIEKIVDTLVSKKEIQPGDRDKVLQALMHKQSQSVETQPLTSNVEMEKFSVTEKRETADKTEASMVLVGALEFLERPTVVFVRLRDAVVLESALEAPVPVRFIFILIGPTIDGMNYHECGRAMAALLADKVFNQAAFQAQSDRELTDAVGDFMDCCIVIPPTEIQNESLLTSLIPFQKKLLQERLRPSNPKLRLDVKPRKPSKSSGPPPEDPLTRTGVPFGGMIRDMKRRYKHYISDLTDALNAQVLAAIIFIYFAALSPAITFGGLLADKVDNMMGVSELMISTSLLGIIFCLIAAQPVLVIGFSGPLLVFEEAFFNFCKSQGIEYIVGRVWVGIWLVVIVVGIVALEGSFLVRFISRFTQEIFSILISLIFIYETFAKLLKIFREHPLTLNYEHLNTSVEDPWHSIVSYQKIFDNATGNVSVVRTVEHQAYPNTALLSMCLMFGCFSIAYYLRMFKNGKFLPGKIRRLLGDFGVPIAIFLMAAIDINIEDTYTQKLVVPKGLQVSNPSMRGWLINPFGEHKSFPVWMMFASIVPAILVFILIFLESQITTLIVSKPERKMVKGSGFHMDLLILVSMGGLSAFFGIPWLSAATVRSVSHANALTVMSKGPKPEIEKVLEQRVSGVVVALLVGLSILMEPILKMIPITALFGIFLYMGITSLSGIQLWDRMLLLLIPKKYHPNEPYATRVSTSKMHVFTAIQMVCLAVLWIVKSSPASLALPFVLILTIPLRMFMTGRLFTEQDMKFLDGDDSKATFEEEPGVDVYSETQMPL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0008514 (organic anion transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015106 (bicarbonate transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0006811 (monoatomic ion transport), GO:0071702 (organic substance transport), GO:0006812 (monoatomic cation transport), GO:0006816 (calcium ion transport), GO:0070509 (calcium ion import), GO:0030001 (metal ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0045178 (basal part of cell), GO:0045177 (apical part of cell), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0009925 (basal plasma membrane), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0016324 (apical plasma membrane), GO:0016323 (basolateral plasma membrane)
Protein: Period 1 isoform X2 (A0A8M2BJY2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm
InterPro domains:
- IPR048814: Period circadian protein homolog 1-3, PAS-A domain (domain) [228-351]
- IPR022728: Period circadian-like, C-terminal (domain) [1160-1323]
- IPR057310: Period circadian protein homolog PER 1-3, bHLH-like domain (domain) [142-199]
- IPR000014: PAS domain (domain) [218-470]
- IPR013655: PAS fold-3 (domain) [382-466]
- IPR035965: PAS domain superfamily (homologous_superfamily) [371-471]
- IPR050760: Period circadian regulator (family) [52-1360]
Sequence:
MNNNNFQAPASCGGFADKAAIEMDEEEGQNNISPAMTDNQSLCPGLNITNESQQTHSGDTDAQSSGIDSTERENDGRLGHGTSTCSSLHGKGSATETTESKSSNGNSPSPPSSSVSFSLLSGSSEQDHSTSQASNSDQPARLQTQRELLKVLRELKIHMPAERRRKGRSSTLASLQYALSCVKQVRANQEYYHQWSVEESHGCCLDLSSFTIEELDNVTSEYTLQNTDTFSVAVSFLSGKVVYISSQAASLLRCKAERLQGALFSELLAPQDVSTFYSSTAPSRLPPWSSCAGTSSQVDCAEEKSMFCRISRGRDSNGEVKYHPFRLTPYQLTLRDSDTSQPEPCCLLIAERVHSGYEAPRIPADKRIFTTSHTPNCLFQEIDERAVPLLGYLPQDLVGKPVLVYLHPEDRLLMVAIHKKILQFAGQPFDHSPLRMRARSGEYLTIDTSWSSFINPWSRKVAFIVGRHKVRTSPLNEDVFTAPEGEEMKTMSPDVPQLNELIHRFLVQPVYGGSSQGYGSLGSSGSHEHQQGATSSSESNGHTSEDQIKPRKPMTFEQICQDMHMVKTSGQQVFIESRNRPPALKQGSLEALAKAADTAEASARDGLASLALSSPPRKELPMIYSYQQINCLDSIVRYLESFNVPGTVKRKCGSSSCTTSSTSDDDKQREGAGATQETLVVTEGSKVVPAAPAHPLTPLALHCKAESVVSATSQCSFSSTIVHVGDKKPPESDIVMMEEPPTTPTASTSAPATSVASPIPVNPQPMPSPTAAVHEKEKEKERRSGGSAGKGLTKAVLSAHTQQEEQAFLNRFRDLSQLRMVQPSGLPPPRRCTSIPGTKGVNSSQNYPSVGNTSSRRHGRGGKRQKHQVDGNIPNNTPISASGPYRGPNPAQIRPNFPSVQQSSNSWAPSAASQTNGAPVGTSFPPSYMTMFPTSSPFSVTQMGTDPSLQTGVPRFPAQGFPSVMPPVMTFMMPNYMFPQLSNPGSQLNPANSQLNAQMNSFGQFPPPVVQMSVPMFNPAMGQFYPLGSQMNPAMPAMIPQQFYNPNYQLNFSNSPSMPAANVSTTPHGQSRSSTPQSTGPQAGERDGAGSPLFQSRCSSPLNLLQLEELPSNRTDATQQTPPPGGGATQGGVVVVQNSSNRSNTQDAKLNDHPEVSESNQDALSTSSDMLDLLLQEDSRSGTGSSGSGSGSGSFASGSNGCSTSGSGTRSSNTSKYFGSIDSSENDQNHKPASGDLGGEQFIKFVLQDPIWLLMANTDDKIMMTYQIPIKDKDSVLKEDRDALKAAQKHQPHFTEEQKKELTQVHPWIQTGCLPKAINVTSCTGCESPPDSSTLPPFDLEFHEMDLNVVLREEAKQEDKLAETAFPLSPPSSDNEQRDNQANLST
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:1901700 (response to oxygen-containing compound), GO:0010035 (response to inorganic substance), GO:0006979 (response to oxidative stress), GO:0010033 (response to organic substance), GO:0009314 (response to radiation), GO:0009416 (response to light stimulus), GO:0042542 (response to hydrogen peroxide), GO:0000302 (response to reactive oxygen species), GO:0009648 (photoperiodism)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Synembryn (A0A8M3B8D2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP
Subcellular location: Cytoplasm
InterPro domains:
Sequence:
MTVDVEKIIQFIKQGDQDNVQSHLDDYNTENSQCFFFDVEERERKKFILISSHLFSGYIIQACFLSCYFSFLIILQCLNREQQRELEEFRRNKVREYVPDSDSDCDSDNSEDPDLVLRRRLAAALIWFIRMRLQPGVLRVCLRTLRIISRDRKALAPLITDYAIITLARLGGISALPTWPEEEDDQWGSSHNDVAPENETDTLPDNDTNTQCPACCSETDDSCCGSTVCAASSVREGGLHFSPMNNTSNPRETQNDHCEESVRKDGVCGLLTRGKRETRGERDEEGEEGHDDGEIWRKEAMKTLCNVIYNSPKAQERASTLRLLHGLSVRIKDGIHSSSPPSGQFYELRLLFLLTALRPELRIELCQERGVSMLTAALEQCLDVIWGETHEVLTDLTAPPLCKELSQRALEILKTLFNITYSVHRQDLDEEAAALYRRLAAVLRHCLLVPCEGEDRKEELQGHTVNVLSALPLQCLDVLLSVRLSEGSEESGGVNMDCVHTLLLFMEKRLDRVRMSTALVTPRATS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0016192 (vesicle-mediated transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: T-box 2a isoform X1 (A0A8M2BCU2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
- IPR046360: T-box transcription factor, DNA-binding domain (domain) [92-280]
- IPR048387: T-box transcription factor 2/3, repressor domain (domain) [513-617]
- IPR022582: T-box transcription factor 2/3, transcription activation domain (domain) [297-372]
- IPR001699: T-box transcription factor (family) [57-627]
- IPR018186: Transcription factor, T-box, conserved site (conserved_site) [102-194]
- IPR002070: Transcription factor, Brachyury (family) [155-233]
- IPR008967: p53-like transcription factor, DNA-binding domain superfamily (homologous_superfamily) [93-275]
- IPR036960: T-box superfamily (homologous_superfamily) [89-281]
Sequence:
MRDPVFTANAMAYHPFHAHRPADFPMSAFLAAAQPSFFPALTLPPGLSKPLADHALSGAAEAGLHAALGHHHQAAHLRSFKGLEPEEDVEDDPKVTLEAKELWDQFHKIGTEMVITKSGRRMFPPFKVRVNGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKSLNFRKQLAMPSMRMYDDQCKVDRDGGDSDDSSCEQTTGRDSVHSPTGPATSPLKFTRSREDKNFNESDNELDQHDDGMIRVSSPEQRPQSPFSPRCEDRVKDRLNLEKKGDYSDSRKENDSAFSIRHLDKDKLDARNVKDQDSSKKEADSVGMSTVKDGFSPLMVQTENPSHFSASHLQSLALSGLHNQHFFNPLSSGQSLLFHPGQFAMTPSAFSTMGMGHLLASMSGASGLENGSLSSQSTSSPNPFPFHLSQHMLASQGISMPTFGGLLPYPYTYMAAAAAAASALPAGSAASSLSRNPFLNNTRPRLRFSPYQIPMSFSQSSGLLTTGIPSTMSAESESSKSGSRESSPMSEHHSHKTGNGQNTGSPKSSGKDSINELQNIQRLVSGLEKHRDASPRSVSPK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0035295 (tube development), GO:0009888 (tissue development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009790 (embryo development), GO:0072006 (nephron development), GO:0003205 (cardiac chamber development), GO:0072001 (renal system development), GO:0060037 (pharyngeal system development), GO:0072009 (nephron epithelium development), GO:0048568 (embryonic organ development), GO:0061326 (renal tubule development), GO:0035050 (embryonic heart tube development), GO:0072359 (circulatory system development), GO:0060429 (epithelium development), GO:0001822 (kidney development), GO:0007507 (heart development), GO:0009792 (embryo development ending in birth or egg hatching), GO:0072080 (nephron tubule development), GO:0048793 (pronephros development), GO:0043009 (chordate embryonic development), GO:0072073 (kidney epithelium development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)