lokahq/bioreason-rl huggingface dataset:
Protein: Junctional adhesion molecule B precursor (A4JYM3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR013106: Immunoglobulin V-set domain (domain) [26-122]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [20-226]
- IPR003598: Immunoglobulin subtype 2 (domain) [31-207]
- IPR042625: Junctional adhesion molecule B (family) [4-306]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [18-210]
- IPR007110: Immunoglobulin-like domain (domain) [18-205]
- IPR003599: Immunoglobulin domain subtype (domain) [25-220]
Sequence:
MLVCVSLLILIHSVPVSPVTVSSRNPKVEVHEFSDAELSCEFKTEKDTNPRIEWKRKDKEKDVSFVYYGERFVGPFQDRADIEGATVRLRRVTQADAGEYRCEVSAPSDSISLGETNVTLRVLVPPQTPSCDVPSSALTGSQVELRCRDRHSIPPAVYTWYKDNRALPIRHPNATYTVNEFTGVLMFQTVSRSDAGQYHCEAKNGVGPPKSCQHTHMQIDDLNVAAVVSAVVLVCVILVLCAFGVCLAHRQGYFSRHRGRSFWIPHCHGVTHISSQNLNPSEHTQHSGYSHPPKEPQDFKHTQSFML
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0002520 (immune system development), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0140253 (cell-cell fusion), GO:0006949 (syncytium formation), GO:0061061 (muscle structure development), GO:0048534 (hematopoietic or lymphoid organ development), GO:0000768 (syncytium formation by plasma membrane fusion), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007520 (myoblast fusion), GO:0042692 (muscle cell differentiation), GO:0051146 (striated muscle cell differentiation), GO:0014902 (myotube differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction), GO:0070161 (anchoring junction), GO:0005911 (cell-cell junction), GO:0043296 (apical junction complex), GO:0070160 (tight junction), GO:0005923 (bicellular tight junction)
Protein: Syntaxin-16 isoform X2 (A0A8M2BJE0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Single- pass type IV membrane protein
InterPro domains:
- IPR010989: SNARE (homologous_superfamily) [70-280]
- IPR000727: Target SNARE coiled-coil homology domain (domain) [220-313]
- IPR006012: Syntaxin/epimorphin, conserved site (conserved_site) [231-270]
- IPR045242: Syntaxin (family) [80-307]
Sequence:
MATRRLTDAFLLMRNNAIQNRQILAEQVSTYDPRRTLNTRSNAALADDRMALVSGISLDPEAAIGVTKRLPPKWVEGVDEIQYEITRIRQKMKELASLHDKHMNRPTLDDSSEEEHAIEITTQEITQMFHRCQRAVTGLQTQSYHCTEQENRLLTNVVSSLAQSLQELSLNFRHTQSGYLKRMKNREERSKHFFDSGPLVEEDEDIALYDRGFTDDQLVLVQQNTVMVEEREREIRQIVQSISDLNEIFRDLAGMVVEQGTVLDRIDFNVEQSCVKTEEGLQQLQKAEQYQKKNRKMLVILILFVIVVVLILILFGTKFS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0035295 (tube development), GO:0009887 (animal organ morphogenesis), GO:0048729 (tissue morphogenesis), GO:0048513 (animal organ development), GO:0009888 (tissue development), GO:0048731 (system development), GO:0035239 (tube morphogenesis), GO:0072001 (renal system development), GO:0060562 (epithelial tube morphogenesis), GO:0002009 (morphogenesis of an epithelium), GO:0060429 (epithelium development), GO:0001822 (kidney development), GO:0072176 (nephric duct development), GO:0060993 (kidney morphogenesis), GO:0072114 (pronephros morphogenesis), GO:0048793 (pronephros development), GO:0072073 (kidney epithelium development), GO:0039022 (pronephric duct development), GO:0072178 (nephric duct morphogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Branchpoint-bridging protein (A0A8M3B3Z3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns
Subcellular location: Nucleus
InterPro domains:
- IPR001878: Zinc finger, CCHC-type (domain) [163-179]
- IPR045071: KH domain-containing BBP-like (family) [4-263]
- IPR004087: K Homology domain (domain) [19-112]
- IPR055256: KHDC4/BBP-like, KH-domain type I (domain) [31-112]
- IPR036612: K Homology domain, type 1 superfamily (homologous_superfamily) [17-145]
Sequence:
MVGLNPEFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECCAKIMIRGKGSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSTEPRSITNTTLCTKCGGAGHISSDCKFTSSFAPRPGEPPQSAQDKARMDKEYLSLMAELGEAPVPSSGGGHNNAPPSGPRPSGPNNNQPPPNRPPWMNSGPTDNRNFHGMHQGPGGPHNFPPPMPNMGGPPMPPNPNGMPPPWMQPPPPPMGQGPAPPGHPMGLLPPPMGMMPPPPPPPNNQPPPPPSGPLPPWQQQAPPPPPTSSMATSAPMPWQQNTTTTSTPATGNLPPWQQPQQTAASASQPPPPMGNPSMVPPPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPMDPNFVTMMGIPGMPPYGMPPAPPPPPPQS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0060041 (retina development in camera-type eye), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0001654 (eye development), GO:0150063 (visual system development), GO:0043010 (camera-type eye development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Catenin delta-1 isoform X1 (A0A8M9Q686)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR000225: Armadillo (repeat) [385-822]
- IPR028435: Plakophilin/Delta catenin (family) [47-863]
- IPR011989: Armadillo-like helical (homologous_superfamily) [355-841]
- IPR016024: Armadillo-type fold (homologous_superfamily) [355-825]
Sequence:
MEQCENAASLLASVREQEMQFERLTRALEEERRSVGPSGTLPRPLPTLQNGRITGDAELERLKLSEGYINGTQYRMLDPGHIVESVTVESDPHEALPIISVETGDDGTTRRTETTVKKVTKTTTTRTVIPSVSDTLSLDGTGSVTGMPSYNSPMDRVYRPPPGPMDYPTSTVPRNYHYGPPAGYDDYRSVPPSEAYTSLSRGTRMDDRYRPVDGYRTLDSAYRTHSRPQLDPYSAQPQVGRMGSAVEISALQRFVPEPYGLEDDQRSLGYDEPDYGMGPAMHYSTMPRLAHPHHAPPPRRTGSYEGTLDGDMSGAGDMFYWGGGAPLAQGERGSMASLDSTLRKGPAPTAWRQPELPEVIAMLNYRLDPVKSNAAAYLQHLTFKNDKVKSEVRRLKGIPALVSMLDNPKKEVHYAACGALKNISYGRDPDNKIAIKNCDGIPALVRLLRKTRDQDLTDTITGTLWNLSSHDSVKMEIVDHALHALSDEVMVPHSGWERGNEGGEESCKPRHLEWETALTNTTGCLRNVSSERSEARRKLRECSGLVDSLMYIVQSQINCKDVDNKLIENSVCLLRNLSYQVHREIPGCERYLESIPVNQGPLPSQKGGCFSSRKGKDEWFSKGKREDDGTSDTIDIPKRTTPAKGYELLFQPEVVRVYTSLLKESKNPSVLEAAAGAVQNLCAGRWTYGRYIRATMRQEHGLPMMTELLSHGNDRVVRAMSGALRNLAIDARNRELLGKHAVPNLVANLPGGGQSQPARALSEETVVSVLSTMAEVVGSSVDAAKTLRSAQGIERLVLINKDSNRSDREVRGAGLVLQIVWGFKELRRTLEKDGWKKTDFMVNLNPPNNTRSNGGYEESTLPLIDRGGKQDREKDMIPLNDIGPDAYSTIDQRGRRNTLDDTLDRSDRDAPQGGMYGERRGSLPLLDSYDENLIVCITRREFPPPAYCPC
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019904 (protein domain specific binding), GO:0019899 (enzyme binding), GO:0019902 (phosphatase binding), GO:0019903 (protein phosphatase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0009790 (embryo development), GO:0048598 (embryonic morphogenesis), GO:0009888 (tissue development), GO:0048731 (system development), GO:0016477 (cell migration), GO:0007369 (gastrulation), GO:0048883 (neuromast primordium migration), GO:0048882 (lateral line development), GO:0048880 (sensory system development), GO:0001667 (ameboidal-type cell migration), GO:0048925 (lateral line system development), GO:0042074 (cell migration involved in gastrulation), GO:0048916 (posterior lateral line development), GO:0008078 (mesodermal cell migration), GO:0048920 (posterior lateral line neuromast primordium migration), GO:0048881 (mechanosensory lateral line system development), GO:0048915 (posterior lateral line system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction), GO:0070161 (anchoring junction), GO:0005911 (cell-cell junction), GO:0005912 (adherens junction)
Protein: RNA-binding motif, single-stranded-interacting protein 3 isoform X3 (A0A8M3AJD4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR000504: RNA recognition motif domain (domain) [56-220]
- IPR002343: Paraneoplastic encephalomyelitis antigen (family) [56-218]
- IPR035979: RNA-binding domain superfamily (homologous_superfamily) [56-200]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [52-218]
Sequence:
MGKRLEQQPMYPQYTYYYPHYLQTKQSYAPPPPPMAPPSPSTNSSSHSAAEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKASGVQAQMAKQQEQDPTNLYISNLPVSMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCDVVIQHFNGKFLKTPPGVPAPTEPLLCKFADGGQKKRQSQSKYPQNGRPWPREGESGMALTYDPTAMQNGFYSSPYSISTNRMIAQTSITPFIAASPVSTYQGAVITPTMDHTISMQPANMMGPLTQQMNHLSLGTTGTYMTAAAAPMQGTYIPQYTAVPASAVSVEGVVTDASPQSVPASSQDASGQQQALGVENTSDHAPTYSFQPAK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0050793 (regulation of developmental process), GO:0023051 (regulation of signaling), GO:0051239 (regulation of multicellular organismal process), GO:0050794 (regulation of cellular process), GO:0090287 (regulation of cellular response to growth factor stimulus), GO:2000026 (regulation of multicellular organismal development), GO:0010646 (regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0090092 (regulation of transmembrane receptor protein serine/threonine kinase signaling pathway), GO:0061035 (regulation of cartilage development), GO:1903844 (regulation of cellular response to transforming growth factor beta stimulus), GO:0017015 (regulation of transforming growth factor beta receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: UDP-glucuronosyltransferase (A8WGC1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Single- pass membrane protein
InterPro domains:
- IPR035595: UDP-glycosyltransferase family, conserved site (conserved_site) [352-395]
- IPR050271: UDP-glycosyltransferase (family) [30-500]
- IPR002213: UDP-glucuronosyl/UDP-glucosyltransferase (family) [20-522]
Sequence:
MRPLACFLSLLSLLSAGECGNVLVWFTEGSHWINMKIVLETLIDRGHDVTVLVPDASLFMKANASDRFSYQPFNVSMDEQEMKVFIEEFLYFSLYEMDQLNFFQMQSKVYEFTSKLQDMSISYCDGVLKSPGLLDKLRKHKFDVVFSDPIYQCSDIVAEELNVPLVYTFRFSLAHAAERMCGQIPAPPSYVPGAMSKLTDRMSFTERIYNMLFYLSQDAFAVFAWKKIDNYYTEYFGRPTSYCEMMGRADIWLIRTYWDFEFPRPFVPNFKYIGGLHCTPAKPLPKDMEEFVQSSGDDGIVVFTLGSLVGKVPKEISNRIASALAQIPQKVLWRYGGEKPDTLGENTRIYKWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGVPMVGIPLFGDQPDNMVHMTTRGAAVVVDSIKSMQPQELVDKLNTVINDPSYKENAMRLSRIHHDRPMKPLDESVFWIEFVMRNKGAKHLRVEAHNLTWYQYHCLDVFAFLTTVLTLVLYICFKMAKFFIMRCCFRSKRKSKKE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0008194 (UDP-glycosyltransferase activity), GO:0016758 (hexosyltransferase activity), GO:0015020 (glucuronosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0048856 (anatomical structure development), GO:0031099 (regeneration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Homeobox protein Nkx-2.8 (A0A8M9P8T3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
- IPR017970: Homeobox, conserved site (conserved_site) [111-134]
- IPR001356: Homeodomain (domain) [76-140]
- IPR020479: Homeodomain, metazoa (domain) [100-134]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [59-136]
- IPR050394: Homeobox NK-like transcription regulators (family) [8-167]
Sequence:
MAISNKFSFTVRSILDLPENDTESIVQHSPLDSFSVSPYSTWTENDRGHISSDDSNIEASPDSTEPDVLSVDTEHEKRKKRRVLFSKAQTYELERRFRQQRYLSAPEREQLAHLLRLTPTQVKIWFQNHRYKMKRARIECAQDLNQPPVLRRVVVPILVRDGKPYQNCTIDTEKGNGIVPPTVPSSPFTVQGFHSLQQQTPFALFPTYQHFTNTAASRHHFCVW
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0035295 (tube development), GO:0048729 (tissue morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0007418 (ventral midline development), GO:0033504 (floor plate development), GO:0009888 (tissue development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0021517 (ventral spinal cord development), GO:0009790 (embryo development), GO:0021508 (floor plate formation), GO:0021510 (spinal cord development), GO:0022008 (neurogenesis), GO:0007399 (nervous system development), GO:0021915 (neural tube development), GO:0021514 (ventral spinal cord interneuron differentiation), GO:0033505 (floor plate morphogenesis), GO:0007417 (central nervous system development), GO:0021515 (cell differentiation in spinal cord), GO:0060429 (epithelium development), GO:0030182 (neuron differentiation), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development), GO:0048699 (generation of neurons), GO:0021953 (central nervous system neuron differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Nuclear transcription factor Y subunit gamma (A0A8M9PN42)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors
Subcellular location: Nucleus
InterPro domains:
- IPR007125: Core Histone H2A/H2B/H3 domain (domain) [33-102]
- IPR050568: Transcription/DNA replication regulator (family) [11-170]
- IPR009072: Histone-fold (homologous_superfamily) [8-117]
Sequence:
MSADSFGAGGSDAQQSLQSFWPRVMEEIRNLTVDFRVQELPLARIKKIMKLDEDVKMISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPRDDLKPPKRQEEVRQSVAPTEPVQYYFTLAQQPSAVQVQGQQQGQQVSAPTATTLQPGQIIIAQPQQGQSAPVTMQVGEGQQVQIVQAAAQGQAQAQTAQPAGQTMQVMQQIITNTGEIQQIPVQLNTGQLQYIRLAQPVSGTQVVQGQIQTLAANTQQLSQTEVQQGQQQFNQFTDGQQLYQIQQVTMPAGQELTQPMFIQSTNQTADGQVTTQVSAD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0060041 (retina development in camera-type eye), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0001654 (eye development), GO:0150063 (visual system development), GO:0043010 (camera-type eye development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005667 (transcription regulator complex), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Disheveled-associated activator of morphogenesis 1 isoform X1 (A0A8M6Z2D8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR011989: Armadillo-like helical (homologous_superfamily) [46-354]
- IPR015425: Formin, FH2 domain (domain) [595-1060]
- IPR014768: Rho GTPase-binding/formin homology 3 (GBD/FH3) domain (domain) [46-421]
- IPR042201: Formin, FH2 domain superfamily (homologous_superfamily) [613-1016]
- IPR014767: Diaphanous autoregulatory domain (domain) [1018-1049]
- IPR016024: Armadillo-type fold (homologous_superfamily) [54-424]
- IPR010472: Formin, FH3 domain (domain) [236-434]
- IPR051425: Formin Homology (family) [5-1057]
- IPR010473: Formin, GTPase-binding domain (domain) [46-233]
Sequence:
MMAPRKRGGRGLSFLCCCLKGSDHPEITYSLRHGSNFTLQTMEPTLPMPPTEELDAMFTELVDELDLTEKHRAAMFALPAEKKWQIYCSKKKEQEENKGATSWPEFYIDQINSMAARKSLLALEKEDEEERNKTIESLKTALRTQPMRFVTRFIDQDGLTCILNFLKTMDYETTESQIHTSLIGCIKALMNNSQGRAHVLSHSESINIIAQSLATENIKTKVAVLEIMGAVCLVPGGHKKILEAMLHYQKFACERTRFQTLLNDLDRSTGRYRDEVNLKTAIMSFINAVLSQGAGETSLEFRIHLRYEFLMLGIQPVIDKLRSHENSTLDRHLDFFEMLRNEDELALAKRFENVHVDTKSATQMFELIRKRINHTDAFPHFISVLQHCLHMPYKKTGNTVQYWVLLDRIVQQIILQNDKGLDPDVAPLENFDVKNVVRMLVNENEVKQWKEQAEKMRKEHNELQQKLEKKERECDAKAQEKEEMMQTLNKMKEKLEKESSEHKLVKQQVADLSARLHEMSNRTNIPGGPPLAPLGPGLPPPPPPPGQAGLPPPPPPGGAPPPPPPPPGGPPPPPGLLGFGAPPPPGGLLGSTLKKKNIPQPSNPLKSFNWTKLSENKLEGTVWLDLDDVRVFKQLDLEDIEKTFSAYQRQQDFLFNNFRQKESEDDTVTSKKVKELSVIDGRRAQNCNILLSKLKLSNEEIKRAILTMDEQEDLPKDMLEQLLKFVPEKSDVDLLEEHKHELERMAKADRFLYEMSRINHYQQRLQSLYFKKKFAERIAEIKPKVEALSKASKEVLQSKNLRQLLEIVLAFGNYMNKGQRGNAYGFKVSSLNKIADTKSSIDKNVTLLHYLITVLEQKYPKVSLIHEDLQNVPVAAKVNMTELEKDINNLRSGLKSVETELEYQRTQPQTYGDKFVSVVSQFITVAGFSFSDIEDSLQDAKDSFGKAVQHFGEDATRMQPDEFFGIFDQFLQGFSEAKQDNENMRRRKEEEERRARMEAQLKEQRERERKSRKAKENCEEDGEFDDLVSALRSGEVFDKDMSKMKHNRKRPVKSSAESSRERPVTKLNF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0021536 (diencephalon development), GO:0060322 (head development), GO:0030900 (forebrain development), GO:0048731 (system development), GO:0021986 (habenula development), GO:0048513 (animal organ development), GO:0021538 (epithalamus development), GO:0072001 (renal system development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development), GO:0001822 (kidney development), GO:0048793 (pronephros development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0005769 (early endosome), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)
Protein: Transcobalamin II (F2Z4S3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted
InterPro domains:
- IPR002157: Cobalamin (vitamin B12)-binding protein (family) [2-314]
- IPR051588: Eukaryotic Cobalamin Transport (family) [2-420]
- IPR027954: Transcobalamin-like, C-terminal domain (domain) [346-421]
Sequence:
MITLLIVSALLALAAGKPCASDHETLLQSLNKQLLRSVDTQDNLPNPSVHIALRLSTQHNLDKENQYLNRLKKEFHEDIEKSLRNGELVVGRLALYILALRSSCHDLSLHLNHNEKNEFLLTHLKKEMEEEKQNIAFSHRPKTNYYQYSLGILALCVSGVRVSTHVSHKLIHAVEHGQIKHGESLCIDSHAMAGMALQCLKNEGISVKDEAELDKALATIKQKLVDSKRADGHMGNEFSTGLAVQALLAMGVEMEECGTAIEALRGDIRKGTYHNPMAASQVLPALYQQSYLHLKSKECRSEDDTLTADVESASEVLPSLGQVAVQVEVIKSNGEASVFPINVPKGSSLFEALNLLQDKQTGFTFKTEDSLWGAFLSVLNDEQARQTDRRYWHVSSDGTSLTQGIKDYKIDSAQRITIKNTGY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0019842 (vitamin binding), GO:0046906 (tetrapyrrole binding), GO:0031419 (cobalamin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0051180 (vitamin transport), GO:0071705 (nitrogen compound transport), GO:0015889 (cobalamin transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)