Protein: Zinc finger E-box-binding homeobox 2 isoform X1 (A0A8M9QAF0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
- IPR008598: Di19, zinc-binding domain (domain) [216-268]
- IPR013087: Zinc finger C2H2-type (domain) [216-1094]
- IPR051574: Zinc finger E-box-binding homeobox (family) [164-1099]
- IPR001356: Homeodomain (domain) [649-711]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [216-1084]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [658-702]
Sequence:
MRELIMADGPRCKRRKQANPRRKNAAVLDFENVVETGSETEEEDRLLVSEEDALLNGAGSPASLVNHESEAPPSPTLSHTLLRKTVDDEDDMKDSGIENVWHENDLLNASIDGTDELKADYDTMGTDVSLEPIGNGTVKSVHCDTDFEDFFGKRKLVDTESHVVSIAEYLQRGDTAIIYPEAPEELSRSRLATPEATGHEENDLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEENFACPLCSYTFAYRTQLERHMATHKPGRDQHQILNQGSGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLIAINGRVRNNLKTGSSPTSASSSPTNNAISQLRHKLENGKPLGLQDQSNHLNIKSEPLDFNDYKLMMASHGYATGSPFLNGGVRGGSPLGIHNSQSPLQHLGMGIEGQMLGYPSLGNNLSEVQKVLQIVDNTVCRQKMDCKPEEISKLKAYMKELGSHIEEQKQGLNSSGGGQGTLPLINHNGATKSIIDYTLEKVNEAKACLQSLTTDSKRQISNIKKEKANHMLDLGMEEKAHENNLMFTPFSCQYCKETFPGPIPLHQHERYLCKMNEEIKAVLQPAQNALTNKPGLFSEKHGLLHPSIIPEKSLNGPISPYKDHMSVLKAYFAMNMEPNSEELLKISIAVGLPQEFVKEWFEQRKVFQYTTSRTPPLDRSPVESIHPVSAHTPTKDSLGIRSPMSLVKGSDRITSPAIPELHNNCDTPLRLSKTPQYSNHKQLGDKMDHSRSNTPSPLNLSSASSKNSHTSSYTPNSFTSEDLQAEPLDLSLPKLMKEPKHILTVKSRLKLNSGPMDHNHVATPREHADEPLNLAYLSKKEFGSPNANSNLDKSSSPMFGLNPFAAKPMYTSLPPQSAFPPPTFMPPVQASLPGLRPYPSLDQISFLPHMAYTYAAGAASFAEMQQRRKYQRKPGFQSELLDGPADYLSSLDDMADPEACLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYEHTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEEREAAEREAREKGHLEPTEMLLNRAYLQGIGPAGYPEHPEREPILRDALNGSIRERLQEVEGAFVKMSRREHDFEEEEDESENKSTDGDTMRDEEENGEHSMDESSKSESKSDHEDAMEDGV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0003682 (chromatin binding), GO:0003700 (DNA-binding transcription factor activity), GO:0005515 (protein binding), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific), GO:0001217 (DNA-binding transcription repressor activity), GO:0001227 (DNA-binding transcription repressor activity, RNA polymerase II-specific)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048589 (developmental growth), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0007389 (pattern specification process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0035295 (tube development), GO:0048729 (tissue morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0001756 (somitogenesis), GO:0009888 (tissue development), GO:0003002 (regionalization), GO:0048468 (cell development), GO:0060560 (developmental growth involved in morphogenesis), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009790 (embryo development), GO:0016477 (cell migration), GO:0014029 (neural crest formation), GO:0035282 (segmentation), GO:0048863 (stem cell differentiation), GO:0048864 (stem cell development), GO:0061009 (common bile duct development), GO:0048732 (gland development), GO:0007369 (gastrulation), GO:0060027 (convergent extension involved in gastrulation), GO:0009953 (dorsal/ventral pattern formation), GO:0002009 (morphogenesis of an epithelium), GO:0060485 (mesenchyme development), GO:0061053 (somite development), GO:0048762 (mesenchymal cell differentiation), GO:0060429 (epithelium development), GO:0003401 (axis elongation), GO:0061008 (hepaticobiliary system development), GO:0009952 (anterior/posterior pattern specification), GO:0001667 (ameboidal-type cell migration), GO:0009792 (embryo development ending in birth or egg hatching), GO:0014033 (neural crest cell differentiation), GO:0060026 (convergent extension), GO:0043009 (chordate embryonic development), GO:0060030 (dorsal convergence), GO:0001837 (epithelial to mesenchymal transition), GO:0042074 (cell migration involved in gastrulation), GO:0001889 (liver development), GO:0035622 (intrahepatic bile duct development), GO:0014032 (neural crest cell development), GO:0060028 (convergent extension involved in axis elongation), GO:0090497 (mesenchymal cell migration), GO:0001755 (neural crest cell migration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)