Protein: mitogen-activated protein kinase kinase (F7EK55)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [175-187]
- IPR017441: Protein kinase, ATP binding site (binding_site) [59-82]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [47-315]
- IPR000719: Protein kinase domain (domain) [53-314]
Sequence:
MSQSKGKKRNPGLKIPREAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSADFVDFTSQCLKKNSKERPTYPELMQHPFFTVHEAKAADVASFVKLILGD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004712 (protein serine/threonine/tyrosine kinase activity), GO:0016301 (kinase activity), GO:0004708 (MAP kinase kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0048511 (rhythmic process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:1905954 (positive regulation of lipid localization), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0032879 (regulation of localization), GO:0032504 (multicellular organism reproduction), GO:0051050 (positive regulation of transport), GO:0022602 (ovulation cycle process), GO:0048522 (positive regulation of cellular process), GO:0042698 (ovulation cycle), GO:0008219 (cell death), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0048609 (multicellular organismal reproductive process), GO:0010942 (positive regulation of cell death), GO:1903530 (regulation of secretion by cell), GO:0012501 (programmed cell death), GO:0051049 (regulation of transport), GO:0051047 (positive regulation of secretion), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0032370 (positive regulation of lipid transport), GO:0009410 (response to xenobiotic stimulus), GO:1905952 (regulation of lipid localization), GO:0060255 (regulation of macromolecule metabolic process), GO:1901700 (response to oxygen-containing compound), GO:0010033 (response to organic substance), GO:0009891 (positive regulation of biosynthetic process), GO:0032892 (positive regulation of organic acid transport), GO:0010941 (regulation of cell death), GO:0031325 (positive regulation of cellular metabolic process), GO:0070887 (cellular response to chemical stimulus), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0002931 (response to ischemia), GO:1903532 (positive regulation of secretion by cell), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0009743 (response to carbohydrate), GO:0010562 (positive regulation of phosphorus metabolic process), GO:2000193 (positive regulation of fatty acid transport), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0051246 (regulation of protein metabolic process), GO:0071310 (cellular response to organic substance), GO:0043067 (regulation of programmed cell death), GO:0043068 (positive regulation of programmed cell death), GO:0032305 (positive regulation of icosanoid secretion), GO:0032368 (regulation of lipid transport), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0032890 (regulation of organic acid transport), GO:0006915 (apoptotic process), GO:0051247 (positive regulation of protein metabolic process), GO:0051046 (regulation of secretion), GO:1901701 (cellular response to oxygen-containing compound), GO:0032306 (regulation of prostaglandin secretion), GO:0051174 (regulation of phosphorus metabolic process), GO:0043065 (positive regulation of apoptotic process), GO:0042981 (regulation of apoptotic process), GO:0051770 (positive regulation of nitric-oxide synthase biosynthetic process), GO:0031399 (regulation of protein modification process), GO:0032303 (regulation of icosanoid secretion), GO:0045937 (positive regulation of phosphate metabolic process), GO:0071322 (cellular response to carbohydrate stimulus), GO:0019220 (regulation of phosphate metabolic process), GO:0051769 (regulation of nitric-oxide synthase biosynthetic process), GO:0031401 (positive regulation of protein modification process), GO:2000191 (regulation of fatty acid transport), GO:0042325 (regulation of phosphorylation), GO:0001932 (regulation of protein phosphorylation), GO:0042327 (positive regulation of phosphorylation), GO:0001934 (positive regulation of protein phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)