Protein: [histone H3]-lysine(4) N-trimethyltransferase (A0A8M1PGA4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR050869: Histone-lysine N-methyltransferase (family) [4-449]
- IPR046341: SET domain superfamily (homologous_superfamily) [9-279]
- IPR001214: SET domain (domain) [7-259]
- IPR002893: Zinc finger, MYND-type (domain) [52-90]
- IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [321-462]
Sequence:
MTVEKTDPVEVFGAGLKGRGLRGTRDLSAGEVVFAEASFAAVVLDSLSLQVCHSCFRRQVNPHRCAQCKFAHYCDRTCQRAAWDEHRKECSAIRNIGKAPNENVRLVARILWRIQKHTGLVSDSQLTTLDMLEDHLSRMTPEDLKELKVDVKTFYTYWPKKSKAVGEDYVSHLFGVISCNGFTLSDQRGLQSVGIGLFPNLCLVNHDCWPNCTVILNHGDQSALDASFHSSRRIELRALEPISAGQELTVSYVDFLSVSTDRQRLLQQQYYFDCKCEHCVNGTKDELMTAVKPTEDGKQPSAEVVKQLTDFSLQALVKIEAARAQGNFHEVIRICRECLEKQDPVFADTNVHVLRVLSTASEVLSFLQQFQEAAGYAQRMVDGYMKLYHPNNAQLGMAIMRAGVTHWHAGLIEAAHGLICRAYGILMITHGPHHPISKDLEAMRRQTEMELRMFKQNEHVYHSMREAALTSKPMSVAGEQVQIKA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0016741 (transferase activity, transferring one-carbon groups), GO:0008276 (protein methyltransferase activity), GO:0008092 (cytoskeletal protein binding), GO:0017022 (myosin binding), GO:0016279 (protein-lysine N-methyltransferase activity), GO:0008168 (methyltransferase activity), GO:0042054 (histone methyltransferase activity), GO:0018024 (histone lysine N-methyltransferase activity), GO:0140938 (histone H3 methyltransferase activity), GO:0008757 (S-adenosylmethionine-dependent methyltransferase activity), GO:0008170 (N-methyltransferase activity), GO:0016278 (lysine N-methyltransferase activity), GO:0042800 (histone H3K4 methyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0032501 (multicellular organismal process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0032259 (methylation), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0003008 (system process), GO:0044237 (cellular metabolic process), GO:0030029 (actin filament-based process), GO:0044238 (primary metabolic process), GO:0032989 (cellular component morphogenesis), GO:0044085 (cellular component biogenesis), GO:1901564 (organonitrogen compound metabolic process), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0019538 (protein metabolic process), GO:0048513 (animal organ development), GO:0043414 (macromolecule methylation), GO:0030036 (actin cytoskeleton organization), GO:0043170 (macromolecule metabolic process), GO:0003013 (circulatory system process), GO:0061061 (muscle structure development), GO:0009888 (tissue development), GO:0016043 (cellular component organization), GO:0044260 (cellular macromolecule metabolic process), GO:0010927 (cellular component assembly involved in morphogenesis), GO:0031033 (myosin filament organization), GO:0055006 (cardiac cell development), GO:0006479 (protein methylation), GO:0008015 (blood circulation), GO:0055001 (muscle cell development), GO:0030239 (myofibril assembly), GO:0022607 (cellular component assembly), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0007015 (actin filament organization), GO:0042692 (muscle cell differentiation), GO:0072359 (circulatory system development), GO:0060537 (muscle tissue development), GO:0003015 (heart process), GO:0071688 (striated muscle myosin thick filament assembly), GO:0043933 (protein-containing complex organization), GO:0007517 (muscle organ development), GO:0006996 (organelle organization), GO:0031032 (actomyosin structure organization), GO:0035051 (cardiocyte differentiation), GO:0097435 (supramolecular fiber organization), GO:0007507 (heart development), GO:0070925 (organelle assembly), GO:0008213 (protein alkylation), GO:0014866 (skeletal myofibril assembly), GO:0014706 (striated muscle tissue development), GO:0048738 (cardiac muscle tissue development), GO:0060047 (heart contraction), GO:0031034 (myosin filament assembly), GO:0060538 (skeletal muscle organ development), GO:0065003 (protein-containing complex assembly), GO:0030240 (skeletal muscle thin filament assembly), GO:0014904 (myotube cell development), GO:0018193 (peptidyl-amino acid modification), GO:0045214 (sarcomere organization), GO:0055013 (cardiac muscle cell development), GO:0007519 (skeletal muscle tissue development), GO:0007010 (cytoskeleton organization), GO:0055007 (cardiac muscle cell differentiation), GO:0018022 (peptidyl-lysine methylation), GO:0051146 (striated muscle cell differentiation), GO:0055003 (cardiac myofibril assembly), GO:0016571 (histone methylation), GO:0055002 (striated muscle cell development), GO:0016570 (histone modification), GO:0034968 (histone lysine methylation), GO:0014902 (myotube differentiation), GO:0140694 (non-membrane-bounded organelle assembly), GO:0018205 (peptidyl-lysine modification), GO:0048741 (skeletal muscle fiber development), GO:0051568 (histone H3-K4 methylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0030017 (sarcomere), GO:0005737 (cytoplasm), GO:0031672 (A band), GO:0031430 (M band), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043292 (contractile fiber), GO:0043228 (non-membrane-bounded organelle), GO:0043229 (intracellular organelle), GO:0099512 (supramolecular fiber), GO:0030016 (myofibril), GO:0043232 (intracellular non-membrane-bounded organelle)