Protein: DNA (cytosine-5-)-methyltransferase (A6KHW2)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR030488: DNA (cytosine-5)-methyltransferase 3B, ADD domain (domain) [416-535]
- IPR029063: S-adenosyl-L-methionine-dependent methyltransferase superfamily (homologous_superfamily) [549-839]
- IPR040552: DNMT3, cysteine rich ADD domain, GATA1-like zinc finger (domain) [401-456]
- IPR001525: C-5 cytosine methyltransferase (family) [561-839]
- IPR050390: DNA Cytosine-5 Methyltransferase (family) [48-667]
- IPR018117: DNA methylase, C-5 cytosine-specific, active site (active_site) [629-641]
- IPR000313: PWWP domain (domain) [229-310]
- IPR049554: DNMT3, ADD domain, PHD zinc finger (domain) [463-512]
- IPR025766: ADD domain (domain) [408-540]
- IPR011011: Zinc finger, FYVE/PHD-type (homologous_superfamily) [456-527]
Sequence:
MKGDSRHLNEEEGASGYEDCIIVNGNCSDQSSDTKDAPSPPVLEAICTEPVCTPETRGRRSSSRLSKREVSSLLNYTQDVVGDGDGEADDGDGSDILMMPKLTRETKDARTPSESPAVRTRNSNSISSLERQRTSPRITRGRQGRYHVQEYPVEFPATKSRRRRASSSASTPWSSPASIELMEDVTPKSSSTPSVDLSQDGPQEGMDATQVDAESRDGDSTEYQDDKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMPGMRWVQWFGDGKFSEIAADKLVALGLFSQHFNLATFNKLVSYRKAMYHTLEKAMVRAGKTFPSRPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNKQPENKSRRRTTIDFAASEYSTPPKRLKTNSYGGKDRGEDEESRERMASDVTNNKGNLEDRCLSCGKKNPVSFHPLFEGGLCQSCRDRFLELFYMYDEDGYQSYCTVCCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAEDAKLQEPWSCYMCLPQRCHGVLRRRKDWNMRLQDFFTTDPDLEEFEPPKLYPAIPAAKRRPIRVLSLFDGIATGYLVLKDLGIKVEKYVASEVCAESIAVGTIKHEGQIKYVNDVRKITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFYHLLNYTRPKEGDNRPFFWMFENVVAMKVNDKKDISRFLACNPVMIDAIKVSAAHRARYFWGNLPGMNRPVIASKNDKLELQDCLEFSRTAKLKKVQTITTKSNSIRQGKNQLFPVVMNGKDDVLWCTELERIFGFPAHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKDYFACE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0014823 (response to activity), GO:0009991 (response to extracellular stimulus), GO:0001666 (response to hypoxia), GO:0007584 (response to nutrient), GO:1901698 (response to nitrogen compound), GO:0009410 (response to xenobiotic stimulus), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0009314 (response to radiation), GO:0070482 (response to oxygen levels), GO:1902074 (response to salt), GO:0009636 (response to toxic substance), GO:0055093 (response to hyperoxia), GO:0071495 (cellular response to endogenous stimulus), GO:1901700 (response to oxygen-containing compound), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0032870 (cellular response to hormone stimulus), GO:0042220 (response to cocaine), GO:1901654 (response to ketone), GO:0010243 (response to organonitrogen compound), GO:0032355 (response to estradiol), GO:0071453 (cellular response to oxygen levels), GO:0071310 (cellular response to organic substance), GO:0033993 (response to lipid), GO:0031667 (response to nutrient levels), GO:0062197 (cellular response to chemical stress), GO:0036296 (response to increased oxygen levels), GO:0036293 (response to decreased oxygen levels), GO:0048545 (response to steroid hormone), GO:0014070 (response to organic cyclic compound), GO:0033273 (response to vitamin), GO:0010212 (response to ionizing radiation), GO:1901701 (cellular response to oxygen-containing compound), GO:1901655 (cellular response to ketone), GO:0043279 (response to alkaloid), GO:0071548 (response to dexamethasone), GO:0071383 (cellular response to steroid hormone stimulus), GO:0031960 (response to corticosteroid), GO:0014074 (response to purine-containing compound), GO:0033189 (response to vitamin A), GO:0071407 (cellular response to organic cyclic compound), GO:0036295 (cellular response to increased oxygen levels), GO:0071396 (cellular response to lipid), GO:0071549 (cellular response to dexamethasone stimulus), GO:0051384 (response to glucocorticoid), GO:0031000 (response to caffeine), GO:0071384 (cellular response to corticosteroid stimulus), GO:0071385 (cellular response to glucocorticoid stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)