Protein: General transcription and DNA repair factor IIH helicase subunit XPD (A6J8M9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR014013: Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type (domain) [7-283]
- IPR010614: RAD3-like helicase, DEAD (domain) [72-256]
- IPR010643: Helical and beta-bridge domain (domain) [271-413]
- IPR006555: ATP-dependent helicase, C-terminal (domain) [525-699]
- IPR006554: Helicase-like, DEXD box c2 type (domain) [8-280]
- IPR002464: DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site (conserved_site) [229-238]
- IPR001945: RAD3/XPD (family) [8-727]
- IPR013020: ATP-dependent helicase Rad3/Chl1-like (family) [8-708]
- IPR045028: Helicase superfamily 1/2, DinG/Rad3-like (family) [7-721]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [16-697]
Sequence:
MKLNVDGLLVYFPYDYIYPEQFSYMLELKRTLDAKGHGVLEMPSGTGKTVSLLALIVAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKLLSFYEQQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQQDASLPHCRFYEEFDTHGRQVPLPAGIYNLDDLKALGQRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQSNLDTLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARETDAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLHTLEIADLADFSPLTLLANFATLVSTYAKGFTIIIEPFDDRTPTITNPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARADKRGKLPRWIQEHLTDSNLNLTVDEGVQVAKYFLRQMAQPFHREDQLGLSLLSLEQLQSEETLQRIEQIAQQL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0009628 (response to abiotic stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0006950 (response to stress), GO:0009790 (embryo development), GO:0001666 (response to hypoxia), GO:0070482 (response to oxygen levels), GO:0048513 (animal organ development), GO:0036293 (response to decreased oxygen levels), GO:0048568 (embryonic organ development)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0009628 (response to abiotic stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0006950 (response to stress), GO:0009790 (embryo development), GO:0001666 (response to hypoxia), GO:0070482 (response to oxygen levels), GO:0048513 (animal organ development), GO:0036293 (response to decreased oxygen levels), GO:0048568 (embryonic organ development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0140513 (nuclear protein-containing complex), GO:0005667 (transcription regulator complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0090575 (RNA polymerase II transcription regulator complex), GO:0000439 (transcription factor TFIIH core complex), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)