Protein: Polypyrimidine tract-binding protein 1 (A0A8M9QFQ9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
- IPR006536: HnRNP-L/PTB (family) [71-573]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [55-573]
- IPR035001: PTBP1, RNA recognition motif 3 (domain) [380-472]
- IPR035000: PTBP1, RNA recognition motif 1 (domain) [73-153]
- IPR021790: PTBP1-like, RNA recognition motif 2 (domain) [187-266]
- IPR000504: RNA recognition motif domain (domain) [73-571]
- IPR055204: Heterogeneous nuclear ribonucleoprotein L, RRM domain (domain) [490-560]
- IPR035979: RNA-binding domain superfamily (homologous_superfamily) [62-571]
Sequence:
MDGRLETDLYPLGSSYVTEIDVHDITVGTKRGSDELFSSCISNGPYIMSSGAANGNDSKKFKGDIRSPGIPSRVIHVRKLPNDINEAEVISLGLPFGKVTNLLMLKGKNQAFLEMNTEESAQTMVSYYSSVTPVIRNHPIFMQYSNHKELKTDNSPNQVRAQAALQAVNAVQTGGMSLAAIDGAGMGSQSPVLRVIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALVQYSDGMTAQHAKLSLDGQNIYNACCTLRISFSKLTSLNVKYNNDKSRDYTRPDLPTGDSQPSFDAQTMAAAALTAPGIISASPYAGAHGFPQAFAIQQAAGLSLQGMPAGALASLSVPGAAAAAAAAAAAGRLGLSGLTAAGNSVLLVSNLNPESVTPQCLFILFGVYGDVMRVKILFNKKENALVQMSDGTQAQLAMSHLNGQKLYGKALRATLSKHTTVQLPREGHEDQGLTKDYSNSPLHRFKKPGSKNYSNIFPPSSTLHLSNIPPSVTEDDLRGLFLSSGAVVKAFKFFQKDRKMALIQLASVEEAIESLIKFHNHDLGENHHLRVSFSKSTI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0042592 (homeostatic process), GO:0022414 (reproductive process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0019953 (sexual reproduction), GO:0007586 (digestion), GO:0048856 (anatomical structure development), GO:0023057 (negative regulation of signaling), GO:0007275 (multicellular organism development), GO:0001775 (cell activation), GO:2000241 (regulation of reproductive process), GO:0032879 (regulation of localization), GO:0007389 (pattern specification process), GO:0051239 (regulation of multicellular organismal process), GO:0009566 (fertilization), GO:0007343 (egg activation), GO:0048871 (multicellular organismal-level homeostasis), GO:0051050 (positive regulation of transport), GO:0003008 (system process), GO:0065008 (regulation of biological quality), GO:2000243 (positive regulation of reproductive process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0048522 (positive regulation of cellular process), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:1903530 (regulation of secretion by cell), GO:0051049 (regulation of transport), GO:0051047 (positive regulation of secretion), GO:0009966 (regulation of signal transduction), GO:0060627 (regulation of vesicle-mediated transport), GO:0060249 (anatomical structure homeostasis), GO:0022600 (digestive system process), GO:0007204 (positive regulation of cytosolic calcium ion concentration), GO:0003002 (regionalization), GO:0010646 (regulation of cell communication), GO:0001894 (tissue homeostasis), GO:0050865 (regulation of cell activation), GO:0007338 (single fertilization), GO:1903532 (positive regulation of secretion by cell), GO:0045746 (negative regulation of Notch signaling pathway), GO:0008593 (regulation of Notch signaling pathway), GO:0010669 (epithelial structure maintenance), GO:0030277 (maintenance of gastrointestinal epithelium), GO:0017157 (regulation of exocytosis), GO:0045921 (positive regulation of exocytosis), GO:0051046 (regulation of secretion), GO:0009953 (dorsal/ventral pattern formation), GO:0060729 (intestinal epithelial structure maintenance), GO:1903307 (positive regulation of regulated secretory pathway), GO:1903305 (regulation of regulated secretory pathway), GO:0017158 (regulation of calcium ion-dependent exocytosis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)