Protein: IL-13 receptor alpha 1 (Q8VHC2)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Single- pass type I membrane protein
InterPro domains:
- IPR003961: Fibronectin type III (domain) [225-335]
- IPR040566: Interleukin-13 receptor subunit alpha-1, Ig-like domain (domain) [29-120]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [27-342]
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [127-334]
- IPR003532: Short hematopoietin receptor, family 2, conserved site (conserved_site) [140-171]
- IPR015321: Type I cytokine receptor, cytokine-binding domain (domain) [129-221]
Sequence:
MARPAWLGELLVLLLFAASLDQVALATEVQPPVTNLSVSVENLCTIVWTWSPPEGASPNCSLRYFSHFDDQQDKKIAPETRRKKELPLNEKICLQVGSQCSTNESEKPSPLVKKCISPPRRGSESAVTELQCTWHNLSYMKCSWLPGKNTSPDTNYTLYYWYSSLGKSLQCENIHREGQHIGCSFKLTKVESNYEHHNIQIMVKDNAGKIRPSYKIVSFTSNVKPGPPHIKHLFLKNGALFVQWKNPQNFSSRCLSYEVEVNSTQTDSYNSNSLEVEEDKCQNSEFDRNMEGASCFISPGVLANTVYTVRVRVKTNKLCFDDNDLWSNWSEALSIGKEPNSTFYTTMLLIIPVFVAVVIIILLFYLKRLKIIIFPPIPDPGKIFKEMFGDQNDDTLHWKKYDIYEKQSKEETDSVVLIENLKKAAP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0140375 (immune receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0004896 (cytokine receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0051240 (positive regulation of multicellular organismal process), GO:0002684 (positive regulation of immune system process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0002682 (regulation of immune system process), GO:0051239 (regulation of multicellular organismal process), GO:0048522 (positive regulation of cellular process), GO:0002696 (positive regulation of leukocyte activation), GO:0042127 (regulation of cell population proliferation), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0002702 (positive regulation of production of molecular mediator of immune response), GO:0002697 (regulation of immune effector process), GO:0060255 (regulation of macromolecule metabolic process), GO:0002700 (regulation of production of molecular mediator of immune response), GO:0002694 (regulation of leukocyte activation), GO:0002699 (positive regulation of immune effector process), GO:0050865 (regulation of cell activation), GO:0050867 (positive regulation of cell activation), GO:0008284 (positive regulation of cell population proliferation), GO:0051251 (positive regulation of lymphocyte activation), GO:0010628 (positive regulation of gene expression), GO:0002637 (regulation of immunoglobulin production), GO:0070665 (positive regulation of leukocyte proliferation), GO:0070663 (regulation of leukocyte proliferation), GO:0002639 (positive regulation of immunoglobulin production), GO:0010468 (regulation of gene expression), GO:0051249 (regulation of lymphocyte activation), GO:0032946 (positive regulation of mononuclear cell proliferation), GO:0050670 (regulation of lymphocyte proliferation), GO:0032944 (regulation of mononuclear cell proliferation), GO:0050864 (regulation of B cell activation), GO:0050871 (positive regulation of B cell activation), GO:0050671 (positive regulation of lymphocyte proliferation), GO:0030888 (regulation of B cell proliferation), GO:0030890 (positive regulation of B cell proliferation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:0098797 (plasma membrane protein complex), GO:0005886 (plasma membrane)