lokahq/bioreason-rl huggingface dataset:
Protein: Tial1 cytotoxic granule-associated RNA binding protein-like 1 (Mapped), isoform CRA_c (A6IA05)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR000504: RNA recognition motif domain (domain) [1-154]
- IPR034496: TIAR, RNA recognition motif 3 (domain) [82-154]
- IPR035979: RNA-binding domain superfamily (homologous_superfamily) [2-157]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [1-163]
Sequence:
MDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQETNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQQVDYSQWGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMGGFGAQPPQGQAPPPVIPPPNQAGYGMASFPTQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding), GO:0035925 (mRNA 3'-UTR AU-rich region binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0010941 (regulation of cell death), GO:0010942 (positive regulation of cell death), GO:0043067 (regulation of programmed cell death), GO:0043068 (positive regulation of programmed cell death), GO:0043065 (positive regulation of apoptotic process), GO:0042981 (regulation of apoptotic process), GO:1904037 (positive regulation of epithelial cell apoptotic process), GO:1904035 (regulation of epithelial cell apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0035770 (ribonucleoprotein granule), GO:0036464 (cytoplasmic ribonucleoprotein granule), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0010494 (cytoplasmic stress granule), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005634 (nucleus)
Protein: POU domain protein (A6J940)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR013847: POU domain (domain) [159-291]
- IPR010982: Lambda repressor-like, DNA-binding domain superfamily (homologous_superfamily) [142-214]
- IPR017970: Homeobox, conserved site (conserved_site) [275-298]
- IPR000327: POU-specific domain (domain) [140-214]
- IPR001356: Homeodomain (domain) [240-304]
- IPR000972: Octamer-binding transcription factor (family) [62-151]
- IPR050255: POU domain transcription factor (family) [32-318]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [219-301]
Sequence:
MVHSSMGAPEIRMSKPLEAEKQSLDSPSEHTDTERNGPDINHQNPQNKASPFSVSPTGPSTKDIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAGLPTQPSKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPTSYSPHLVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGHPLCHSPTPGHHQQHKPEPSRQPLGYRLDGPEPQRRPWPLVEPCPLPALIAAGTWCWGQPVRPQGAPA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Protein Wnt (A6HJT1)
Organism: Rattus norvegicus (Rat)
Function: Ligand for members of the frizzled family of seven transmembrane receptors
Subcellular location: Secreted, extracellular space, extracellular matrix
InterPro domains:
- IPR009141: Wnt-3 protein (family) [42-355]
- IPR005817: Wnt (family) [42-355]
- IPR043158: Wnt, C-terminal domain (homologous_superfamily) [295-355]
- IPR018161: Wnt protein, conserved site (conserved_site) [206-215]
Sequence:
MEPHLLGLLLGLLLSGTRVLAGYPIWWSLALGQQYTSLASQPLLCGSIPGLVPKQLRFCRNYIEIMPSVAEGVKLGIQECQHQFRGRRWNCTTIDDSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTSTICGCDSHHKGPPGEGWKWGGCSEDADFGVLVSREFADARENRPDARSAMNKHNNEAGRTTILDHMHLKCKCHGLSGSCEVKTCWWAQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVETLRAKYALFKPPTERDLVYYENSPNFCEPNPETGSFGTRDRTCNVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCVFHWCCYVSCQECIRIYDVHTCK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019904 (protein domain specific binding), GO:0005102 (signaling receptor binding), GO:0001664 (G protein-coupled receptor binding), GO:0005109 (frizzled binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050793 (regulation of developmental process), GO:0040008 (regulation of growth), GO:0050794 (regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0045595 (regulation of cell differentiation), GO:0001558 (regulation of cell growth)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Alkaline phosphatase (A6JWK7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor. Membrane; Lipid-anchor, GPI-anchor
InterPro domains:
- IPR001952: Alkaline phosphatase (family) [5-510]
- IPR018299: Alkaline phosphatase, active site (active_site) [108-116]
- IPR017850: Alkaline-phosphatase-like, core domain superfamily (homologous_superfamily) [20-502]
Sequence:
MQGAWVLLLLGFRLQLSLSVIPVEEENPAFWNQKAADALNVAKKLQPIQTSAKNLIIFLGDGMGVPTVTATRILKGQLEGNLGPETPLAMDHFPYMALSKTYSVDRQVPDSASTATAYLCGVKTNYKTIGVSAAARFDQCNTTFGNEVLSVMYRAKKAGKSVGVVTTTRVQHASPAGTYVHTVNRNWYGDADMPASALQEGCKDIATQLVSNMDINVILGGGRKYMFPAGTPDPEYPNDVNETGTRLDGKNLVQEWLSKHQGSQYVWNRQELIQKSLDPSVTYLMGLFEPVDTKFEIQRDPLMDPSLKDMTEAALHVLSRNPKGFYLFVEGGRIDRGHHLGTAYLALTEAVMFDSAIERASQLTSEQDTLTIVTADHSHVFSFGGYTLRGTSIFGLAPLNALDGKPYTSILYGNGPGYVGTGERPNVTDAESHDPSYQQQAAVPVKSETHGGEDVAIFARGPQAHLLHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADENRPTTPVQNSTTTTTTTTTTTTTRVQNSASSLGPATGPLALALLAKALMLLLGAPADF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0043167 (ion binding), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0043169 (cation binding), GO:0042578 (phosphoric ester hydrolase activity), GO:0046872 (metal ion binding), GO:0000287 (magnesium ion binding), GO:0016791 (phosphatase activity), GO:0046914 (transition metal ion binding), GO:0008270 (zinc ion binding), GO:0004035 (alkaline phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0044237 (cellular metabolic process), GO:0009991 (response to extracellular stimulus), GO:0006793 (phosphorus metabolic process), GO:0031667 (response to nutrient levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098552 (side of membrane), GO:0009986 (cell surface), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0009897 (external side of plasma membrane), GO:0005886 (plasma membrane)
Protein: long-chain-fatty-acid--CoA ligase (A6JTS4)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR025110: AMP-binding enzyme, C-terminal domain (domain) [520-595]
- IPR022272: Lipocalin family conserved site (conserved_site) [134-146]
- IPR020845: AMP-binding, conserved site (conserved_site) [243-254]
- IPR042099: ANL, N-terminal domain (homologous_superfamily) [70-504]
- IPR000873: AMP-dependent synthetase/ligase domain (domain) [82-394]
- IPR045851: AMP-binding enzyme, C-terminal domain superfamily (homologous_superfamily) [506-605]
Sequence:
MLLGASLVGALLFSKLVLKLPWTQVGFSLLLLYLGSGGWRFIRVFIKTVRRDVFGGMVLLKVKTKVRRYLQERKTVPLLFASVVRRHPDKTALIFEGTNTHWTFRQLDDYSSSVANFLQARGLVSGNVVALFMENRNEFVGLWLGMAKLGVEAALINTNLRRDALRHCLDTSKARALIFGSEMASAVYEIQAILDPTLTLFCSGSWEPSTVPANTEHLDPLLEDAPKHLPSIPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRMRPDDIVYDCLPLYHSAGNIVGIGQCVLHGMTVVIRKKFSASRFWDDCIKYNCTIVQYIGELCRYLLNQPPREAESRHKVRMALGNGLRQSIWTDFSSRFHIPQVAEFYGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGQPGQLVGRIIQQDPLRRFDGYLNQGANNKKIASDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEGTLSRLLQMADVAVYGVEVPGAEGRAGMAAVASPTSNCDLESFAQTLKKELPLYARPIFLRFLPELHKTGTFKFQKTELRKEGFDPSVVKDPLFYLDARTGCYVALDQEAYTRIQAGEEKL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:0007584 (response to nutrient), GO:0009991 (response to extracellular stimulus), GO:0031667 (response to nutrient levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005739 (mitochondrion), GO:0098590 (plasma membrane region), GO:0098857 (membrane microdomain), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0045121 (membrane raft), GO:0005740 (mitochondrial envelope), GO:0019866 (organelle inner membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0044853 (plasma membrane raft), GO:0031966 (mitochondrial membrane), GO:0005901 (caveola), GO:0005743 (mitochondrial inner membrane)
Protein: F-box only protein 2 (A6IU64)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR001810: F-box domain (domain) [47-94]
- IPR036047: F-box-like domain superfamily (homologous_superfamily) [45-143]
- IPR039752: F-box only protein (family) [37-296]
- IPR008979: Galactose-binding-like domain superfamily (homologous_superfamily) [113-296]
- IPR007397: F-box associated (FBA) domain (domain) [113-296]
Sequence:
MDGDGDPESVSHPEEASPEEQPEEAGAEASAEEEQPREEEEEETEAVEYLAELPEPLLLRVLAELPATELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEGSADDERDHWQQFYFLSKRRRNLLRNPCGEEDLEGWCDVEHGGDGWRVEELPGDSGVEFTHDDSVKKYFASSFEWCRKAQVIDLQAEGYWEELLDTTQPAIVVKDWYSGRTDAGSLYELTVRLLSEHEDVLAEFNTGQVAVPEDGSWMEISHTFTDYGPGVRYVRFEHGGQDSVYWKGWFGARVTNSSVWVEP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0065007 (biological regulation), GO:0048523 (negative regulation of cellular process), GO:0050794 (regulation of cellular process), GO:0008285 (negative regulation of cell population proliferation), GO:0042127 (regulation of cell population proliferation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0098794 (postsynapse), GO:0019898 (extrinsic component of membrane), GO:0036477 (somatodendritic compartment), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0045211 (postsynaptic membrane), GO:0019897 (extrinsic component of plasma membrane), GO:0098590 (plasma membrane region), GO:0120025 (plasma membrane bounded cell projection), GO:0097447 (dendritic tree), GO:0045202 (synapse), GO:0099568 (cytoplasmic region), GO:0005886 (plasma membrane), GO:0043005 (neuron projection), GO:0097060 (synaptic membrane), GO:0098890 (extrinsic component of postsynaptic membrane), GO:0099243 (extrinsic component of synaptic membrane), GO:0032838 (plasma membrane bounded cell projection cytoplasm), GO:0098978 (glutamatergic synapse), GO:0030425 (dendrite), GO:0120111 (neuron projection cytoplasm), GO:0032839 (dendrite cytoplasm)
Protein: Gamma-soluble NSF attachment protein (A6IXL2)
Organism: Rattus norvegicus (Rat)
Function: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus
Subcellular location: Membrane; Peripheral membrane protein
InterPro domains:
- IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [1-276]
- IPR000744: NSF attachment protein (family) [8-278]
Sequence:
MAAQKINEGLEHLAKAEKYLKTGFLKWKPDYDSAASEYGKAAVAFKNAKQFEQAKDACLREAVAHESNRALFHAAKAYEQAGMMLKEMQKLPEAVQLIEKASMMYLENGTPDTAAMALERAGKLIENVDPEKAVQLYQQTANVFENEERLRQAVELLGKASRLLVRGRRFDEAALSIQKEKNIYKEIENYPTCYKKTIAQVLVHLHRNDYVAAERCVRESYSIPGFNGSEDCAALEQLLEGYDQQDQDQVSEVCNSPLFKYMDNDYAKLGLSLVVPGGGIKKKSPATPQAKPEGAAGAAAEEEEDEYSGGLC
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0065008 (regulation of biological quality), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0090066 (regulation of anatomical structure size), GO:0006810 (transport), GO:0032535 (regulation of cellular component size), GO:0016192 (vesicle-mediated transport), GO:0061024 (membrane organization), GO:0061025 (membrane fusion), GO:0008361 (regulation of cell size), GO:0006906 (vesicle fusion), GO:0090174 (organelle membrane fusion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction), GO:0045202 (synapse)
Protein: Similar to crinkled (Predicted) (A6KTE4)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR011029: Death-like domain superfamily (homologous_superfamily) [108-196]
- IPR000488: Death domain (domain) [116-189]
- IPR039200: Ectodysplasin-A receptor-associated adapter protein (family) [1-198]
Sequence:
MASPDDPLRSDHMAKEPVEDTDPSTLSFAMSDKYPIQDTGLPKAKECDAVTSNCPPNSDDQHQGEENDFPDSTGDPLSGVSRNQPCKEGCPCSSCSPRAPTISDLLNDQDLLDVIRIKLDPCHPTVKNWRNFASKWGMPYDELCFLEQRPQSPTLEFLFRNSQRTVGQLMELCRLYHRADVEKILRRWVDEEWPHRGPLDGSMHF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023056 (positive regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0010647 (positive regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0010646 (regulation of cell communication), GO:1902533 (positive regulation of intracellular signal transduction), GO:1902531 (regulation of intracellular signal transduction), GO:1901222 (regulation of NIK/NF-kappaB signaling), GO:1901224 (positive regulation of NIK/NF-kappaB signaling)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Neurturin (Q9QZG0)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted
InterPro domains:
- IPR029034: Cystine-knot cytokine (homologous_superfamily) [80-161]
- IPR001839: Transforming growth factor-beta, C-terminal (domain) [69-161]
- IPR043401: Glial cell line-derived neurotrophic factor family (family) [38-161]
Sequence:
SSLLSVWMCQEGLLLGHRLGPALAPLRRPPRTLDARIARLAQYRALLQGAPDAVELRELSPWVARPSGPRRRAGPRRRRARPGSRPCGLRELEVRVSELGLGYTSDETVLFRYCAGACEAAIRIYDLGLRRLRQRRRVRKERVRAHPCCRPTAYEDEVSFL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0140677 (molecular function activator activity), GO:0030545 (signaling receptor regulator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (signaling receptor activator activity), GO:0048018 (receptor ligand activity), GO:0008083 (growth factor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048870 (cell motility), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0035556 (intracellular signal transduction), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0016043 (cellular component organization), GO:0007166 (cell surface receptor signaling pathway), GO:0016477 (cell migration), GO:0022008 (neurogenesis), GO:0048863 (stem cell differentiation), GO:0048864 (stem cell development), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0007167 (enzyme-linked receptor protein signaling pathway), GO:0000165 (MAPK cascade), GO:0060485 (mesenchyme development), GO:0048762 (mesenchymal cell differentiation), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0001667 (ameboidal-type cell migration), GO:0014033 (neural crest cell differentiation), GO:0031175 (neuron projection development), GO:0007169 (transmembrane receptor protein tyrosine kinase signaling pathway), GO:0048699 (generation of neurons), GO:0014032 (neural crest cell development), GO:0120036 (plasma membrane bounded cell projection organization), GO:0090497 (mesenchymal cell migration), GO:0001755 (neural crest cell migration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0042995 (cell projection), GO:0120025 (plasma membrane bounded cell projection), GO:0043005 (neuron projection), GO:0030424 (axon)
Protein: RCG29282, isoform CRA_c (A6K8Y9)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR016135: Ubiquitin-conjugating enzyme/RWD-like (homologous_superfamily) [6-176]
- IPR050113: Ubiquitin-conjugating enzyme (family) [9-164]
- IPR000608: Ubiquitin-conjugating (UBC), catalytic core domain (domain) [8-174]
- IPR023313: Ubiquitin-conjugating enzyme, active site (active_site) [82-97]
Sequence:
MARPLVPSSQKALLLELKGLQEEPVEGFRVTLVDEGDLYNWEVAIFGPPNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKESKGKDREYTDIIRKQVLGTKVDS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0010942 (positive regulation of cell death), GO:0051130 (positive regulation of cellular component organization), GO:0051128 (regulation of cellular component organization), GO:0010941 (regulation of cell death), GO:0044089 (positive regulation of cellular component biogenesis), GO:0044087 (regulation of cellular component biogenesis), GO:0070848 (response to growth factor), GO:1901216 (positive regulation of neuron death), GO:1901214 (regulation of neuron death), GO:0090083 (regulation of inclusion body assembly), GO:0043067 (regulation of programmed cell death), GO:0043068 (positive regulation of programmed cell death), GO:0043065 (positive regulation of apoptotic process), GO:0042981 (regulation of apoptotic process), GO:0043525 (positive regulation of neuron apoptotic process), GO:0043523 (regulation of neuron apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0098793 (presynapse), GO:0005737 (cytoplasm), GO:0030054 (cell junction), GO:0045202 (synapse)
Protein: Platelet-activating factor acetylhydrolase (A6JJ36)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted, extracellular space
InterPro domains:
- IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [47-346]
- IPR016715: Platelet-activating factor acetylhydrolase-like, eukaryote (family) [5-345]
Sequence:
MVPLKLRVLFCLLCCLPRVHPLYWQDPSFFDFRPSVMFHKLQSVMSAVSAGRCKIPKGNGSYPVGCTDMMFGYGNESIFLRLYYPAQDQGPHDTVWVPNIEYFWGLSKFLGTPTFVGNILRLLYGSLTAPASWNFPLRTGEKYPLIIFSHGLGAFRTIYSAIGAALASYGFIVATVEHRDGSASATYYFEDQAAAKMENRSWFYLKKIKQEESERARKEQVRQRAKECSKALSAILDIEHGNPKENVLGLPFDMKQLKDSIDETKIAVMGHSFGGATVFQALSEDQRFRCGIALDPWMFPVSEELYSRVPQPLFFINSAEFQTPKDIAKMKNFYQPDKERKMITIK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0052689 (carboxylic ester hydrolase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0006954 (inflammatory response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)