Protein: [histone H3]-trimethyl-L-lysine(27) demethylase (V9GWA8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR019734: Tetratricopeptide repeat (repeat) [86-378]
- IPR051630: Transcriptional Corepressor and Histone Demethylase (family) [32-1205]
- IPR048562: Lysine-specific demethylase 6A/B-like, C-terminal helical domain (domain) [1060-1115]
- IPR046941: Lysine-specific demethylase 6, GATA-like domain superfamily (homologous_superfamily) [1125-1191]
- IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [61-1064]
- IPR003347: JmjC domain (domain) [907-1070]
- IPR048560: Lysine-specific demethylase 6A/B-like, GATA-like (domain) [1132-1192]
Sequence:
MPVKFDILRISGNEEKKMAAEKARGEGEEGSFSLTVEEKKALCGLDSSFFGFLSLCKDGVKMKTLLNKAIHCYESLIVKAEGKVESDFFCQLGHFNLLLEDYSKALSSYQRYYSLQTDYWKNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAKEIHLRLGFMFKVNTDYESSLKHFQLALRDSNVCTLSSVEIQFHIAHLYEIQRKYHSAKAAYEQLLQIESLPSQVKATVLQQLGWMHHNMDLVGDNTTKERYAIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESCNQTQDAIKCYLNATRSKSCSNTSVLISRIKFLQAQLCNLPQSSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQQNVSDSWNSVHTASHHPVQQQVYTQCFTTQKLQGLGKDQQRPFQTGSTRYIHAACVDNQNQNGNHTLPQNSKGDTQNHSSLHIPTSEEQKIFNFTKESKDSRSKSLSPKTSRQDRDTSNIYVNAKEHSKNIHEITSVPISSLNNEDSVSPNLIIVDNPQLSVLVGEAMDSVDHDSRTCDKVNNVHPTLHKKPDNLTASSPSSASSTETLSLKVTEQMHTHIVTSFISPNSGLDTINGGPENSESSISVSVGLRPRPQIIPSMSVSIYSSSTEVLKACRNLGKNGLPNGHILLDICPPPRPPTSPYPPLPKEKLNPPTPSIYLENKRDAFFPPLHQFCINPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHIVEVRTQFLQPADENWDPSGTKKIWRYENKSSHTTIAKYAQYQACSFQESLREENERKTQVKDYSDNESTCSDISRRRQKVPFKTIKCGINIDLSDNKKWKLQLHELTKLPAFVRVVSAGNLLSHVGYTILGMNSVQLCMKVPGSRIPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNITWNVGPLTAFQYKLAVERYEWNKLQSIKSVVPMVHLSWNMARNIKVSDPKLFEMIKYCLLKILKQCQTLREALVAAGKEVLWHGRINDEPAPYCSICEVEVFNLLFVTNESNSQKTYIVHCQNCARKTSGNLENFVVLEQYKMEDLIQVYDQFTLAPSLSSSS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0051641 (cellular localization), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0051234 (establishment of localization), GO:0048523 (negative regulation of cellular process), GO:0051640 (organelle localization), GO:0009892 (negative regulation of metabolic process), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0046907 (intracellular transport), GO:0051656 (establishment of organelle localization), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0006810 (transport), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0051649 (establishment of localization in cell), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0080090 (regulation of primary metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0051647 (nucleus localization), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0007097 (nuclear migration), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0051252 (regulation of RNA metabolic process), GO:0051253 (negative regulation of RNA metabolic process), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:0010468 (regulation of gene expression), GO:2001141 (regulation of RNA biosynthetic process), GO:1902679 (negative regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903507 (negative regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0045892 (negative regulation of DNA-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)