Protein: PR domain zinc finger protein 12 (A0A6Q8PH01)
Organism: Homo sapiens (Human)
Function: Involved in the positive regulation of histone H3-K9 dimethylation
Subcellular location: Nucleus
InterPro domains:
- IPR013087: Zinc finger C2H2-type (domain) [243-298]
- IPR046341: SET domain superfamily (homologous_superfamily) [43-216]
- IPR050331: Zinc finger (family) [226-302]
- IPR044406: PRDM12, PR/SET domain (domain) [84-213]
- IPR001214: SET domain (domain) [86-213]
- IPR017126: PR-domain zinc finger protein PRDM12 (family) [1-303]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [252-302]
Sequence:
MMGSVLPAEALVLKTGLKAPGLALAEVITSDILHSFLYGRWRNVLGEQLFEDKSHHASPKTAFTAEVLAQSFSGEVQKLSSLVLPAEVIIAQSSIPGEGLGIFSKTWIKAGTEMGPFTGRVIAPEHVDICKNNNLMWEVFNEDGTVRYFIDASQEDHRSWMTYIKCARNEQEQNLEVVQIGTSIFYKAIEMIPPDQELLVWYGNSHNTFLGIPGVPGLEEDQKKNKHEDFHPADSAAGPAGRMRCVICHRGFNSRSNLRSHMRIHTLDKPFVCRFCNRRFSQSSTLRNHVRLHTGERPYKCQASLPPNLAPGDG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140104 (molecular carrier activity), GO:0140597 (protein carrier chaperone), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0140713 (histone chaperone activity), GO:1990226 (histone methyltransferase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0048869 (cellular developmental process), GO:0009628 (response to abiotic stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0044237 (cellular metabolic process), GO:0032259 (methylation), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0051606 (detection of stimulus), GO:0071704 (organic substance metabolic process), GO:0003008 (system process), GO:0044238 (primary metabolic process), GO:0009581 (detection of external stimulus), GO:0009266 (response to temperature stimulus), GO:1901564 (organonitrogen compound metabolic process), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0019538 (protein metabolic process), GO:0043414 (macromolecule methylation), GO:0016043 (cellular component organization), GO:0009582 (detection of abiotic stimulus), GO:0050877 (nervous system process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0050906 (detection of stimulus involved in sensory perception), GO:0036211 (protein modification process), GO:0022008 (neurogenesis), GO:0043412 (macromolecule modification), GO:0030030 (cell projection organization), GO:0050961 (detection of temperature stimulus involved in sensory perception), GO:0007399 (nervous system development), GO:0006479 (protein methylation), GO:0016048 (detection of temperature stimulus), GO:0062149 (detection of stimulus involved in sensory perception of pain), GO:0007600 (sensory perception), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0050951 (sensory perception of temperature stimulus), GO:0008213 (protein alkylation), GO:0031175 (neuron projection development), GO:0019233 (sensory perception of pain), GO:0048699 (generation of neurons), GO:0050965 (detection of temperature stimulus involved in sensory perception of pain), GO:0120036 (plasma membrane bounded cell projection organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)