Protein: Telomeric repeat-binding factor (A0A8M9QAZ0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat
Subcellular location: Chromosome, telomere. Nucleus
InterPro domains:
- IPR001005: SANT/Myb domain (domain) [451-506]
- IPR030657: Telomeric repeat-binding factor 2 (family) [7-372]
- IPR017357: Telomeric repeat-binding factor 1/2 (family) [13-509]
- IPR036507: Telomere repeat-binding factor, dimerisation domain superfamily (homologous_superfamily) [2-203]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [458-506]
- IPR013867: Telomere repeat-binding factor, dimerisation domain (domain) [16-196]
- IPR017930: Myb domain (domain) [459-508]
Sequence:
MSDKPCEPSWEQIVNRWSFDFYAFQAFSAFRNGDYTAFTHFINIIESVVVRPVDGHPDMIPQLRLMQFLSRINNGDKLDLTFEEPKTPLESALDVLESICRDMSVPHPEQQLIRHAISEMLVMVCIRSGEFEKAEEMLKHFSSSSDSAGKKKLLLNLIRCRRSSHSVLQLSSYSHFKQDMLQFVERLFSVPEPFLLQMLRRSGWPSQRPEVRRSTQNNRRFTGKPSKRTPPHSSAAEDHGAECVSAVSRQGLQQVFDLLSEQYGVGISFFQLQDSVEVEAQQQQEGGVAGPELCLTLSETPMQTVILSDTEEQDEPRRYAGMTISRLVQEEDSQISAEHTHIEDDEEEEQTHTHRGGDCSLSEPQCSSTQRSTPARLCKRSNTRVQQRSIRVSSGSEPEVDSTSPAAHTRRSTPTSTHTRTTKRSKWLDASGIQDNWSDEDSLFHTSTAPAKKYTRKMWSVQESEWLKQGVVRYGVGHWERIRSSFPFAGRTAVNLKDRWRTMVKLKMV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0042162 (telomeric DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051641 (cellular localization), GO:0055085 (transmembrane transport), GO:0006807 (nitrogen compound metabolic process), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0033036 (macromolecule localization), GO:0044237 (cellular metabolic process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0044238 (primary metabolic process), GO:0046483 (heterocycle metabolic process), GO:0098660 (inorganic ion transmembrane transport), GO:0006810 (transport), GO:0070727 (cellular macromolecule localization), GO:0016043 (cellular component organization), GO:0034220 (monoatomic ion transmembrane transport), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0045184 (establishment of protein localization), GO:0098655 (monoatomic cation transmembrane transport), GO:0098662 (inorganic cation transmembrane transport), GO:0071705 (nitrogen compound transport), GO:0006974 (cellular response to DNA damage stimulus), GO:0072594 (establishment of protein localization to organelle), GO:0006259 (DNA metabolic process), GO:0071702 (organic substance transport), GO:0008104 (protein localization), GO:0006996 (organelle organization), GO:0006811 (monoatomic ion transport), GO:0033365 (protein localization to organelle), GO:0006812 (monoatomic cation transport), GO:0000723 (telomere maintenance), GO:0051276 (chromosome organization), GO:0006812 (monoatomic cation transport), GO:0006816 (calcium ion transport), GO:0070585 (protein localization to mitochondrion), GO:0030001 (metal ion transport), GO:0032200 (telomere organization), GO:0016233 (telomere capping), GO:0006813 (potassium ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)