Protein: Mast/stem cell growth factor receptor (B7SCI8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein
InterPro domains:
- IPR027263: Mast/stem cell growth factor receptor (family) [1-977]
- IPR050122: Receptor Tyrosine Kinase (family) [241-932]
- IPR008266: Tyrosine-protein kinase, active site (active_site) [789-801]
- IPR001245: Serine-threonine/tyrosine-protein kinase, catalytic domain (domain) [592-923]
- IPR013151: Immunoglobulin-like beta-sandwich domain (domain) [220-304]
- IPR000719: Protein kinase domain (domain) [591-938]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [1-520]
- IPR003598: Immunoglobulin subtype 2 (domain) [49-500]
- IPR001824: Tyrosine-protein kinase, receptor class III, conserved site (conserved_site) [650-663]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [34-508]
- IPR007110: Immunoglobulin-like domain (domain) [37-310]
- IPR017441: Protein kinase, ATP binding site (binding_site) [597-625]
- IPR020635: Tyrosine-protein kinase, catalytic domain (domain) [591-925]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [566-924]
- IPR003599: Immunoglobulin domain subtype (domain) [43-412]
Sequence:
MRGARGAWDLLCVLLVLLRGQTGTSQPSASPGEPSPPSIQPAQSELIVEAGDTIRLTCTDPAFVKWTFEILDVRIENKQSEWIREKAEATHTGKYTCVSGSGLRSSIYVFVRDPAVLFLVGLPLFGKEDNDALVRCPLTDPQVSNYSLIECDGKSLPTDLKFVPNPKAGITIKNVKRAYHRLCIRCAAQREGKWMRSDKFTLKVRAAIKAIPVVSVPETSHLLKEGDTFTVICTIKDVSTSVDSMWIKLNPQPQSKAQVKRNSWHQGDFNYERQETLTISSARVNDSGVFMCYANNTFGSANVTTTLKVVEKGFINIFPVKNTTVFVTDGENVDLVVEFEAYPKPEHQQWIYMNRTPTNRGEDYVKSDNQSNIRYVNELRLTRLKGTEGGTYTFLVSNSDVSASVTFDVYVNTKPEILTYDRLMNGRLQCVAAGFPEPTIDWYFCTGAEQRCTVPVPPVDVQIQNASVSPFGKLVVQSSIDSSVFRHNGTVECKASNAVGKSSAFFNFAFKGNSKEQIQPHTLFTPLLIGFVVTAGLMGIIVMVLAYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTVGGPTLVITEYCCYGDLLNFLRRKRDSFIFSKQEEQADAALYKNLLHSKESSCDSSNEYMDMKPGVSYVVPTKTDKRRSARIDSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIRNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAAMYEVMKTCWDADPLKRPTFKQVVQLIEKQISDSSKHIYSNLANCNPNPENPVVVDHSVRVNSVGSSTSSTQPLLVHEDA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004713 (protein tyrosine kinase activity), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0008152 (metabolic process), GO:0022414 (reproductive process), GO:0019953 (sexual reproduction), GO:0048856 (anatomical structure development), GO:0048870 (cell motility), GO:0042221 (response to chemical), GO:0008283 (cell population proliferation), GO:0051240 (positive regulation of multicellular organismal process), GO:0006807 (nitrogen compound metabolic process), GO:0051301 (cell division), GO:0051239 (regulation of multicellular organismal process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0065008 (regulation of biological quality), GO:0050793 (regulation of developmental process), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0040017 (positive regulation of locomotion), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0040012 (regulation of locomotion), GO:0009628 (response to abiotic stimulus), GO:0023056 (positive regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0019222 (regulation of metabolic process), GO:0071704 (organic substance metabolic process), GO:0003008 (system process), GO:0044237 (cellular metabolic process), GO:0098727 (maintenance of cell number), GO:0019827 (stem cell population maintenance), GO:0051094 (positive regulation of developmental process), GO:0048609 (multicellular organismal reproductive process), GO:0044238 (primary metabolic process), GO:0007610 (behavior), GO:0048522 (positive regulation of cellular process), GO:2000145 (regulation of cell motility), GO:0009314 (response to radiation), GO:0044057 (regulation of system process), GO:0048513 (animal organ development), GO:0009966 (regulation of signal transduction), GO:0035019 (somatic stem cell population maintenance), GO:0044089 (positive regulation of cellular component biogenesis), GO:0044087 (regulation of cellular component biogenesis), GO:0006793 (phosphorus metabolic process), GO:0010035 (response to inorganic substance), GO:0007611 (learning or memory), GO:0045595 (regulation of cell differentiation), GO:0051128 (regulation of cellular component organization), GO:0051962 (positive regulation of nervous system development), GO:0008284 (positive regulation of cell population proliferation), GO:0016477 (cell migration), GO:0009967 (positive regulation of signal transduction), GO:0007276 (gamete generation), GO:0045597 (positive regulation of cell differentiation), GO:0048167 (regulation of synaptic plasticity), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0051130 (positive regulation of cellular component organization), GO:0043170 (macromolecule metabolic process), GO:2000147 (positive regulation of cell motility), GO:0007283 (spermatogenesis), GO:2000026 (regulation of multicellular organismal development), GO:0042127 (regulation of cell population proliferation), GO:0045933 (positive regulation of muscle contraction), GO:0010646 (regulation of cell communication), GO:0050673 (epithelial cell proliferation), GO:0062012 (regulation of small molecule metabolic process), GO:0007632 (visual behavior), GO:0010647 (positive regulation of cell communication), GO:0031323 (regulation of cellular metabolic process), GO:0008354 (germ cell migration), GO:0050877 (nervous system process), GO:0099177 (regulation of trans-synaptic signaling), GO:0080090 (regulation of primary metabolic process), GO:0017145 (stem cell division), GO:0008593 (regulation of Notch signaling pathway), GO:0048103 (somatic stem cell division), GO:0050769 (positive regulation of neurogenesis), GO:0090257 (regulation of muscle system process), GO:0030334 (regulation of cell migration), GO:0060491 (regulation of cell projection assembly), GO:0043412 (macromolecule modification), GO:0048168 (regulation of neuronal synaptic plasticity), GO:0120034 (positive regulation of plasma membrane bounded cell projection assembly), GO:0030335 (positive regulation of cell migration), GO:0010038 (response to metal ion), GO:0045747 (positive regulation of Notch signaling pathway), GO:0050890 (cognition), GO:0009416 (response to light stimulus), GO:0031344 (regulation of cell projection organization), GO:0060284 (regulation of cell development), GO:0007423 (sensory organ development), GO:0010720 (positive regulation of cell development), GO:0050804 (modulation of chemical synaptic transmission), GO:1904251 (regulation of bile acid metabolic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0007612 (learning), GO:0051960 (regulation of nervous system development), GO:0036211 (protein modification process), GO:0008542 (visual learning), GO:0031346 (positive regulation of cell projection organization), GO:0045987 (positive regulation of smooth muscle contraction), GO:0019216 (regulation of lipid metabolic process), GO:0048232 (male gamete generation), GO:0048169 (regulation of long-term neuronal synaptic plasticity), GO:0120032 (regulation of plasma membrane bounded cell projection assembly), GO:0018193 (peptidyl-amino acid modification), GO:0016310 (phosphorylation), GO:0046686 (response to cadmium ion), GO:0050767 (regulation of neurogenesis), GO:0043586 (tongue development), GO:0019218 (regulation of steroid metabolic process), GO:0006937 (regulation of muscle contraction), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0006468 (protein phosphorylation), GO:0008306 (associative learning), GO:0006940 (regulation of smooth muscle contraction), GO:0018212 (peptidyl-tyrosine modification), GO:0018108 (peptidyl-tyrosine phosphorylation), GO:0031272 (regulation of pseudopodium assembly), GO:0046777 (protein autophosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098552 (side of membrane), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0009986 (cell surface), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0012505 (endomembrane system), GO:0009897 (external side of plasma membrane), GO:0030141 (secretory granule), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0098562 (cytoplasmic side of membrane), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0009898 (cytoplasmic side of plasma membrane), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0001669 (acrosomal vesicle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)