Protein: ABC transporter G family member 43 (Q8GU86)
Organism: Oryza sativa subsp. japonica (Rice)
Function: ABC transporter modulating cadmium (Cd) import, thus controlling Cd(2+) accumulation to prevent phytotoxicity . Confers high tolerance to Cd in yeast . Prevents leaf bacteria proliferation, such as Xanthomonas oryzae pv. oryzicola (Xoc) RS105 and X. oryzae pv. oryzae (Xoo) PXO99, by triggering Cd accumulation, which in turn impairs bacterial virulence factors
Subcellular location: Cell membrane; Multi-pass membrane protein
InterPro domains:
- IPR003593: AAA+ ATPase domain (domain) [196-1090]
- IPR034003: ATP-binding cassette transporter, PDR-like subfamily G, domain 2 (domain) [849-1087]
- IPR043926: ABC transporter family G domain (domain) [402-453]
- IPR034001: ATP-binding cassette transporter, PDR-like subfamily G, domain 1 (domain) [173-426]
- IPR029481: Pleiotropic ABC efflux transporter, N-terminal domain (domain) [114-164]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [173-1097]
- IPR013581: Plant PDR ABC transporter associated (domain) [740-806]
- IPR013525: ABC-2 type transporter, transmembrane domain (domain) [523-1391]
- IPR003439: ABC transporter-like, ATP-binding domain (domain) [170-1104]
Sequence:
MAGEITPSGSRRSWLSSGAASLARSLRDGDDPFRRSAAASRRDAGDDEENLRWAALEKLPTYDRMRRGILRKAVDGGGDGEGAGSLFKADEVDIANLDPREGRELMERVFKAVEDDNERFLRRFRDRLDQVGIELPKIEVRYQHLDIEADVHVGKRALPTLLNATINTLEGLVSLFISSNKRKLKILNDVNGIIKPSRMTLLLGPPSSGKSTLMRALTGKPDKNLKVSGEITYCGHTFKEFYPERTSAYVSQHDLHNPEMTVRETLDFSRRCLGSGARYDMLSELTRRERNAGIKPDPEIDALMKATVVEGKQNNIVTDLVLKALGLDICADTIVGGAMIRGISGGQKKRVTTGEMLTGPATALFMDEISTGLDSSSTFQIVKYIRQVTHVMNATVMMSLLQPPPETYALFDDIVLIAEGYIVYHGPRENILEFFESAGFRCPERKGVADFLQEVTSRKDQQQYWFLEQDHYRYVSVEEFAQNFKKFHVGQKLQKELQVPYDKSKTHPAALTTKKYGLSSLESLKAVMSREWLLMKRNSFLFIFKAFQLFVLGFITMTLFLRTKMPHEKFSDTSKYVGALTASLITIMFNGFGELQLTIDKLPIFYKQRDFLFFPAWTYGLANIILKVPLSLMESSLWIVLTYYVVGFAPAAGRFFKQFLAYFWTHQMALALFRLLGAILRSMVVANTFGMFVLLLIFLFGGFLVSRKDIKPWWIWGYWTSPMMYSNNALSVNEFLASRWAIPNNDSSISAPTIGKAFLQSKGYFTGEWGYWLSIGAMIGFMIVFNILYLCALTFLRPIGSASTVVSDDDTKSELEAESNQEQMSEVINGTNGTENRRSQRGMVLPFQPLSLSFNHMNYYVDMPAEMKAQGFTESRLQLLSDISGAFRPGVLTALVGVSGAGKTTLMDVLAGRKTSGTIEGDIKLSGYPKKQETFARISGYCEQTDIHSPNLTVYESIVYSAWLRLSSEVDKNTRKVFVEEVMSLVELDVLRDALVGLPGVSGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRNTVNTGRTVVCTIHQPSIDIFESFDELLLLKRGGRVIYAGQLGLHSQILVEYFEAIPGVPKITEGYNPATWMLEVSSSLAEARLDIDFAEVYANSALYRSNQELIKQLSVPPPGFQDLSFPTKYSQNFLNQCVANTWKQFQSYWKDPPYNAMRYVMTLLYGLVFGTVFWRRGKNIESVNDLNNLLGATYAAVFFLGAANLLTLLPVVSVERTVFYREKAAGMYSPLSYAFAQGFVEFCYSAVQGVLYTILIYSMIGYEWKADKFFYFLFFMIAAFAYFTLFSMMLVACTASEMLAAVLVSFVLSSWNNFAGFIIPRPLIPVWWRWFYWANPVSWTIYGVIASQFADSDRVVTVPGQSTTMVVKDFLEKNMGFKHDFLGYVVLAHFGYVIIFFFLFGYGIKCLNFQKR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0140657 (ATP-dependent activity), GO:0042626 (ATPase-coupled transmembrane transporter activity), GO:0022857 (transmembrane transporter activity), GO:0140359 (ABC-type transporter activity), GO:1901474 (azole transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0015399 (primary active transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0050793 (regulation of developmental process), GO:0065008 (regulation of biological quality), GO:0051239 (regulation of multicellular organismal process), GO:0060688 (regulation of morphogenesis of a branching structure), GO:0010817 (regulation of hormone levels), GO:0006810 (transport), GO:0022603 (regulation of anatomical structure morphogenesis), GO:2000032 (regulation of secondary shoot formation), GO:1905428 (regulation of plant organ formation), GO:0009914 (hormone transport), GO:1905428 (regulation of plant organ formation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)