Protein: Cytoplasmic FMR1-interacting protein (A6KD28)
Organism: Rattus norvegicus (Rat)
Subcellular location: Synapse, synaptosome
InterPro domains:
- IPR009828: CYRIA/CYRIB, Rac1 binding domain (domain) [64-273]
- IPR008081: Cytoplasmic FMR1-interacting (family) [1-1252]
Sequence:
MAAQVTLEDALSNVDLLEELPLPDQQPCIEPPPSSLLYQPNFNTNFEDRNAFVTGIARYIEQATVHSSMNEMLEEGQEYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVTKLMNFMYFQRNAIERFCGEVRRLCHAERRKDFVSEAYLITLGKFINMFAVLDELKNMKCSVKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNKITQSLQQQLEVISGYEELLADIVNLCVDYYENRMYLTPSEKHMLLKVMGFGLYLMDGSVSNIYKLDAKKRINLSKIDKYFKQLQVVPLFGDMQIELARYIKTSAHYEENKSRWTCTSSSSSPQYNICEQMIQIREDHMRFISELARYSNSEVVTGSGRQEAQKTDAEYRKLFDLALQGLQLLSQWSAHVMEVYSWKLVHPTDKYSNKDCPDNAEEYERATRYNYTTEEKFALVEVIAMIKGLQVLMGRMESVFNHAIRHTVYAALQDFSQVTLREPLRQAIKKKKNVIQSVLQAIRKTVCDWETGHEPFNDPALRGEKDPKSGFDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGSKKTLRSSLEGPTILDIEKFHRESFFYTHLINFSETLQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILETKEASMMEYVLYSLDLYNDSAHYALTKFNKQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKVMAGSLLLDKRLRSECKNQGATIHLPPSNRYETLLKQRHVQLLGRSIDLNRLITQRVSAAMYKSLELAIGRFESEDLTSVVELDGLLEINRMTHKLLSRYLTLDSFDAMFREANHNVSAPYGRITLHVFWELNYDFLPNYCYNGSTNRFVRTVLPFSQEFQRDKQPNAQPQYLHGSKALNLAYSSIYGSYRNFVGPPHFQVICRLLGYQGIAVVMEELLKVVKSLLQGTILQYVKTLMEVMPKICRLPRHEYGSPGILEFFHHQLKDIVEYAELKTVCFQNLREVGNAVLFCLLIEQSLSLEEVCDLLHAAPFQNILPRVHVKEGERVDAKMKRLESKYAPLHLVPLIERLGTPQQIAIAREGDLLTKERLCCGLSMFEVILTRIRTFLDDPIWRGPLPSNGVMHVDECVEFHRLWSAMQFVYCIPVGTHEFTVEQCFGDGLHWAGCMIIVLLGQQRRFAVLDFCYHLLKVQKHDGKDEIIKNVPLKKMVERIRKFQILNDEIITILDKYLKSGDGESTPVEHVRCFQPPIHQSLASS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0000339 (RNA cap binding), GO:0000340 (RNA 7-methylguanosine cap binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0009628 (response to abiotic stimulus), GO:0051051 (negative regulation of transport), GO:0042221 (response to chemical), GO:0051240 (positive regulation of multicellular organismal process), GO:0032879 (regulation of localization), GO:0071840 (cellular component organization or biogenesis), GO:0051239 (regulation of multicellular organismal process), GO:0045927 (positive regulation of growth), GO:0050793 (regulation of developmental process), GO:0065008 (regulation of biological quality), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0051094 (positive regulation of developmental process), GO:0040008 (regulation of growth), GO:0048522 (positive regulation of cellular process), GO:0048639 (positive regulation of developmental growth), GO:0045597 (positive regulation of cell differentiation), GO:0051602 (response to electrical stimulus), GO:0050773 (regulation of dendrite development), GO:0051049 (regulation of transport), GO:0001558 (regulation of cell growth), GO:0071495 (cellular response to endogenous stimulus), GO:1901700 (response to oxygen-containing compound), GO:0051130 (positive regulation of cellular component organization), GO:0030307 (positive regulation of cell growth), GO:0044089 (positive regulation of cellular component biogenesis), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0044087 (regulation of cellular component biogenesis), GO:2000026 (regulation of multicellular organismal development), GO:1901698 (response to nitrogen compound), GO:1900006 (positive regulation of dendrite development), GO:0070887 (cellular response to chemical stimulus), GO:0031641 (regulation of myelination), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0045595 (regulation of cell differentiation), GO:0016043 (cellular component organization), GO:0051128 (regulation of cellular component organization), GO:0051962 (positive regulation of nervous system development), GO:0090066 (regulation of anatomical structure size), GO:0048638 (regulation of developmental growth), GO:1901652 (response to peptide), GO:0071417 (cellular response to organonitrogen compound), GO:0032535 (regulation of cellular component size), GO:0045773 (positive regulation of axon extension), GO:0031344 (regulation of cell projection organization), GO:0071310 (cellular response to organic substance), GO:0060284 (regulation of cell development), GO:0010720 (positive regulation of cell development), GO:1901699 (cellular response to nitrogen compound), GO:0050769 (positive regulation of neurogenesis), GO:0051960 (regulation of nervous system development), GO:1903421 (regulation of synaptic vesicle recycling), GO:0060491 (regulation of cell projection assembly), GO:0043434 (response to peptide hormone), GO:0061387 (regulation of extent of cell growth), GO:0050770 (regulation of axonogenesis), GO:0032870 (cellular response to hormone stimulus), GO:0010243 (response to organonitrogen compound), GO:0031346 (positive regulation of cell projection organization), GO:0030516 (regulation of axon extension), GO:0120034 (positive regulation of plasma membrane bounded cell projection assembly), GO:1901701 (cellular response to oxygen-containing compound), GO:0120032 (regulation of plasma membrane bounded cell projection assembly), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:1900029 (positive regulation of ruffle assembly), GO:0071375 (cellular response to peptide hormone stimulus), GO:0050772 (positive regulation of axonogenesis), GO:0032868 (response to insulin), GO:0010976 (positive regulation of neuron projection development), GO:0008361 (regulation of cell size), GO:1901653 (cellular response to peptide), GO:0050767 (regulation of neurogenesis), GO:0032869 (cellular response to insulin stimulus), GO:1900027 (regulation of ruffle assembly), GO:0010975 (regulation of neuron projection development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0032433 (filopodium tip), GO:0150034 (distal axon), GO:0042995 (cell projection), GO:0044297 (cell body), GO:0030427 (site of polarized growth), GO:0098793 (presynapse), GO:0030054 (cell junction), GO:0044306 (neuron projection terminus), GO:0044292 (dendrite terminus), GO:0098794 (postsynapse), GO:0036477 (somatodendritic compartment), GO:0005737 (cytoplasm), GO:0120025 (plasma membrane bounded cell projection), GO:0043679 (axon terminus), GO:0045202 (synapse), GO:0043025 (neuronal cell body), GO:0043197 (dendritic spine), GO:0097447 (dendritic tree), GO:0030426 (growth cone), GO:0043195 (terminal bouton), GO:0098858 (actin-based cell projection), GO:0044295 (axonal growth cone), GO:0030425 (dendrite), GO:0043005 (neuron projection), GO:0060076 (excitatory synapse), GO:0030175 (filopodium), GO:0030424 (axon), GO:0044309 (neuron spine)