lokahq/bioreason-rl huggingface dataset:
Protein: RCG44672 (A6I587)
Organism: Rattus norvegicus (Rat)
Subcellular location: Inflammasome
InterPro domains:
- IPR007111: NACHT nucleoside triphosphatase (domain) [464-758]
- IPR001370: BIR repeat (repeat) [58-347]
- IPR040535: NLRC4, helical domain (domain) [766-872]
- IPR028789: Baculoviral IAP repeat-containing protein 1 (family) [1-1403]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [954-1381]
- IPR053882: Nlrc4-like, winged helix domain (domain) [689-740]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [397-600]
Sequence:
MAAQGEAFEERICEFDDDLVSEFSTLLRVDALQVLKRQQEEDHKTRMKMKKGFNAQMRSEAKRLKTFVTYDTFRSWTPQEMAAAGFYYTGVRHGVQCFCCSLILFATRLRKVPIEVHRKLQPECEFLSGKDVGNIGKYDIRVKSPETLPRGGRARYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLQSKKSAEEIAKYIQTYEGFLHVTGEHFVNSWVRRELPVVSAYSNDSVFANEGLRMDTFKDWPHESPMAVEALVKAGLFYTGKKDIVQCFSCGGCMENWKEGDDPIEDHTKFFPNCVFLQTLKSSAEVIPALQSHCARPEAMETTSESNHEDGVAVHSSVADLGQSEAQWCQEARSLSEQLRGTYTKASFRHMNLPEAYSSLGTDHLLGCEVFLISKHVSRPVQVALTIPEVFANLSSVMCVEGEAGSGKTTFLKRIAFLWASGCCPLLNRFQLVFYLSLRSIRADQGLADIICAQLLEAGGCISEVSLSSGIQHLQHQVLFLLDDYSGMDSLPQALDTLITKNYLSRTCLLMAVHTNRVRDIRPYLETVLQIKEFPFYNTVYILKKIFSHDIIRVRRFINYFGFHEYLQGIHKTPLFVAGVCADWLQNPSDQPFQDVTIFKSYMQYLFLKHKATAGPLQATVSSCGHLALTGLFSSSFEFSSDDLIEAGVDEDEELSTCLMSKFTAQRLRPVYRFLSPLFQEFLAAMRLSELLGSDSQEDQDLGLYYLRQINSPLKAMSIYHTFLRYVSNHPSSKAGPKVISHLLQLVDEKESPENTSENEDYMKLHPETLLWSQCLRGLLQLSPESFSLFISERLLNIALNFAYQSNTVAACSPVILQFLQGRTLDLKVLNLQYFWDHPETLLLLKSIQVLFNGNNRVQRIDFSLMDKSFEKIQPPTIDQDYAFAFQPMSECQRNLAEKENIIKNYDDMKYQDPLNISSGYWKLSPKPYKIPRLEVGVNNMGPADQALLHVLMEVFSASQSIEFHLFNSSGFLESIRPALELNKTSVTKCSMSRLELSRAEQELLLTLPALQSLEVSGTSQIPDQLFHNLDKFLGLKELSVRLDGTQDMLSVLPGEFPNLHHMEKLSIHTSTESDLSKLVKLIQNSPNLHDFHLKCDFLSNCESLMAALASCKKLREIEFSGRCFEAVPFVNILSNFASLKILNLRNQQFPDKETSEKFAQALGSLRNLEELHLPTGDGIHQVAKPIVRRCLQLPCLRVLVFAETLDDDSVLEIAKGATSGGFQNLENLDLTLNHKITEEGYRNFFQALDNLPNLQNLDISRHIPECIQVQASTVKALGQCVSRLPSLTRLGMLSWLLDEEDMKVINDVKERHPQSKRLTVHWRWVVPFSPVIQK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0001101 (response to acid chemical), GO:1901698 (response to nitrogen compound), GO:0009611 (response to wounding), GO:0010033 (response to organic substance), GO:1901700 (response to oxygen-containing compound), GO:0010243 (response to organonitrogen compound), GO:0043200 (response to amino acid), GO:0048678 (response to axon injury)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043204 (perikaryon), GO:0005622 (intracellular anatomical structure), GO:0036477 (somatodendritic compartment), GO:0005737 (cytoplasm), GO:0042995 (cell projection), GO:0044297 (cell body), GO:0043025 (neuronal cell body), GO:0120025 (plasma membrane bounded cell projection), GO:0043005 (neuron projection)
Protein: Decay accelarating factor 1, isoform CRA_e (A6IBX9)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR000436: Sushi/SCR/CCP domain (domain) [1-170]
- IPR050350: Complement & Cell Adhesion Regulators (family) [2-224]
- IPR035976: Sushi/SCR/CCP superfamily (homologous_superfamily) [4-169]
Sequence:
MNFFPIGTTVEFECRPGFQKVTSRTGKSTCLEELVWSPVVEFCKKRACPNPRELKNGHINIPTDILFGSEIIFSCDKGYKLVGVTSTFCSITGNAVDWDDVFPVCTTIFCPDPPKINNGRIREESDSYAYRQSVTYSCDQGFILVGNSSVHCTLNGEVGEWSSAPPKCIERHKVPTKTPPEVDIPSTMPHESTLINFPSTRAPLSHKPTTVKVPGTRVKPTSHKPTEVKVPATQHVPVSKTTVRHPTRTSKDRGESNSGGDHFIYGFVAVIVTIDSIILIKTLWWTILSSNRSSDLQGKKKRENVPE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140678 (molecular function inhibitor activity), GO:0004857 (enzyme inhibitor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0048519 (negative regulation of biological process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0019953 (sexual reproduction), GO:0044706 (multi-multicellular organism process), GO:0042221 (response to chemical), GO:0002683 (negative regulation of immune system process), GO:0009719 (response to endogenous stimulus), GO:0044703 (multi-organism reproductive process), GO:0048583 (regulation of response to stimulus), GO:0002682 (regulation of immune system process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0048585 (negative regulation of response to stimulus), GO:0007276 (gamete generation), GO:0050777 (negative regulation of immune response), GO:0007567 (parturition), GO:0050776 (regulation of immune response), GO:1901698 (response to nitrogen compound), GO:0002697 (regulation of immune effector process), GO:0002698 (negative regulation of immune effector process), GO:1901700 (response to oxygen-containing compound), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0007283 (spermatogenesis), GO:0043434 (response to peptide hormone), GO:1901652 (response to peptide), GO:0030449 (regulation of complement activation), GO:0010243 (response to organonitrogen compound), GO:0002921 (negative regulation of humoral immune response), GO:0045916 (negative regulation of complement activation), GO:0002920 (regulation of humoral immune response), GO:0048232 (male gamete generation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0045177 (apical part of cell), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0016324 (apical plasma membrane)
Protein: Interleukin 10 receptor, alpha (A6J435)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [22-237]
- IPR003961: Fibronectin type III (domain) [7-113]
- IPR050650: Type II Cytokine and Tissue Factor Receptors (family) [12-421]
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [26-228]
Sequence:
MLPRLLPFLVSISSLSLGFRAHGTELPSPSSVWFEARFFQHILRWMSIPNQSESTYYEVALKKYGTSVWKDIHICSKAQTLSCDLTTSTLDLYHSSGYRARVRAVDNSQYSNWTITETRFTVDEVILTVDSVTLKVSNGFIYGTIHPPRPNLVPVGDEYEQIFTHHRIYRVCIRKFSEQKNITKTVEQENFTLEVPKGMRKFCVKVMPHVESRINKAEWSEEQCLHVTTEHYFTVTNLSIFFLSILILCGALVCLVLLWYIRHPGKLPAVLVFEKPPDFLLANPRCPETLDDIHILDLEAFPKVSPELKDSDLHGSTDSGFGSGKPSLQTEESQFFLLDSHAQIQETLGKEGSSELQDTCGDNTDSGICLQESSLHSSMGPPWKQQFGYTHQDQDDSDLVQNSPGHPKHTQDGSALGHGCLLEPEVPEEKDQVMVTFQGYQKQTRWKEEAAEPLDGEIPLAEAFDPELGVRLQGDSAWPPVALATGYLKQESQGMASAPPGTPSRQWNQLAEECSLLGVVSCEDLSIESLGFAHELVPLDCGAASSGLLDSLGTNLVTLPLISSLQIEE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0005488 (binding), GO:0038023 (signaling receptor activity), GO:0005515 (protein binding), GO:0004888 (transmembrane signaling receptor activity), GO:0140375 (immune receptor activity), GO:0019838 (growth factor binding), GO:0019955 (cytokine binding), GO:0004896 (cytokine receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0065008 (regulation of biological quality), GO:0042221 (response to chemical), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:0050794 (regulation of cellular process), GO:0050803 (regulation of synapse structure or activity), GO:1901700 (response to oxygen-containing compound), GO:0043207 (response to external biotic stimulus), GO:0051128 (regulation of cellular component organization), GO:0010033 (response to organic substance), GO:0009617 (response to bacterium), GO:0002237 (response to molecule of bacterial origin), GO:0032496 (response to lipopolysaccharide), GO:0050807 (regulation of synapse organization), GO:0033993 (response to lipid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Protein tyrosine phosphatase, receptor-type, F interacting protein, binding protein 2, isoform CRA_d (A6I7S3)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR058914: Liprin-beta-1/2, coiled-coil domain (domain) [1-55]
- IPR037619: Liprin-beta-1/2, SAM domain 3 (domain) [567-638]
- IPR029515: Liprin (family) [1-702]
- IPR001660: Sterile alpha motif domain (domain) [408-640]
- IPR037617: Liprin-beta-1/2, SAM domain 1 (domain) [408-471]
- IPR037618: Liprin-beta-1/2, SAM domain 2 (domain) [482-544]
- IPR013761: Sterile alpha motif/pointed domain superfamily (homologous_superfamily) [374-658]
Sequence:
MLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQKEQEEKQRKAEELLQELKHLKIKVEELENERNQYEWELKATKAEVAQLQEQVALKDAEIERLHSQLSRSSALHSDHAERDQEIHRLKMGMETLRVANEDKDRRIEELTGLLNQYLRVKEIVMATQGSSERTLSINEDEIEGSFRKWNTTSKSPEEVMKQEVSPRCSSPTPGPPPLPQKSLETRAQKKLSCSLEDLRCESGNKCINGNQTSPVGEPKDSSFLAEQKYPTLPGKLSGATPNGEAAKSPPTASLQPDSSGSSQPKLNRGWSISAPVLGDTEGGWEDIVMTNELSSTSSGTESSPQSPLTPDGKRSPKGIKKFWGKIRRTQSGNFNTDTPGMVEFRRGGLRATAGPRLSRTRDTKGQKCDANAPFAQWSTERVCTWLQDFGLAQYVIFARQWVASGHTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINTKQEEKSALLDHVWVTRWLDDIGLPQYKDQFYESRVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPNCLHRRPADESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNALIGPEAEQEKRDKMASPAYTPLTTTAKVRPRKLGFSHFGNMRKKKFDESTDYICPMEPGDAVSDSHRVYGVYRGLSPLDNHELDGLDQVGQIS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0065008 (regulation of biological quality), GO:0023051 (regulation of signaling), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0001505 (regulation of neurotransmitter levels), GO:0060627 (regulation of vesicle-mediated transport), GO:1903530 (regulation of secretion by cell), GO:0099177 (regulation of trans-synaptic signaling), GO:0051049 (regulation of transport), GO:0010646 (regulation of cell communication), GO:0017157 (regulation of exocytosis), GO:0051588 (regulation of neurotransmitter transport), GO:0051046 (regulation of secretion), GO:0046928 (regulation of neurotransmitter secretion), GO:0050804 (modulation of chemical synaptic transmission), GO:1903305 (regulation of regulated secretory pathway), GO:2000300 (regulation of synaptic vesicle exocytosis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098793 (presynapse), GO:0030054 (cell junction), GO:0045202 (synapse)
Protein: Glycylpeptide N-tetradecanoyltransferase (A6JM25)
Organism: Rattus norvegicus (Rat)
Function: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins
InterPro domains:
- IPR022677: Glycylpeptide N-tetradecanoyltransferase, C-terminal (domain) [341-522]
- IPR022676: Glycylpeptide N-tetradecanoyltransferase, N-terminal (domain) [174-327]
- IPR016181: Acyl-CoA N-acyltransferase (homologous_superfamily) [148-528]
- IPR000903: Glycylpeptide N-tetradecanoyltransferase (family) [58-529]
- IPR022678: Glycylpeptide N-tetradecanoyltransferase, conserved site (conserved_site) [277-505]
Sequence:
MAEDSESAASQQSLELDDQDTCGIDGDNEEETEHAKGSPGGDLGAKKKKKKQKRKKEKPNSGGTKSDSASDSQEIKIQQSSKHNAIWQQISAGAAMGGDTMEGEWIDLRMYHKNPTIPIQKLQDIQRAMELLSACQGPARNIDEATKRRYQFWDTQPVPKLNEVITSHGAIEPDKDNIRQEPYSLPQGFMWDTLDLSNAEVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISAIPANIRIYDSVKRMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLPKPVATCRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPKDIRAVRELINVYLKQFHLAPVMGDEEVAHWFLPREHIIDTFVVESPSGKLTDFLSFYTLPSTVMHHPAHKSLKAAYSFYNIHTETPLLDLMNDALIIAKLKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWRCPGTDSEKVGLVLQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0019107 (myristoyltransferase activity), GO:0016410 (N-acyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0019538 (protein metabolic process), GO:0044249 (cellular biosynthetic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0036211 (protein modification process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0009059 (macromolecule biosynthetic process), GO:0043412 (macromolecule modification), GO:0034645 (cellular macromolecule biosynthetic process), GO:0042157 (lipoprotein metabolic process), GO:0006497 (protein lipidation), GO:0031365 (N-terminal protein amino acid modification), GO:0043543 (protein acylation), GO:0018193 (peptidyl-amino acid modification), GO:0042158 (lipoprotein biosynthetic process), GO:0006498 (N-terminal protein lipidation), GO:0018377 (protein myristoylation), GO:0006499 (N-terminal protein myristoylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Retinoic acid receptor responder protein 2 (A6K0G1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted
InterPro domains:
- IPR046350: Cystatin superfamily (homologous_superfamily) [31-114]
- IPR029562: Retinoic acid receptor responder protein 2 (family) [1-125]
Sequence:
MKCLLISLALWLGTADIHGTELELSETQRRGLQVALEEFHRHPPVQWAFQEIGVDSADDLFFSAGTFVRLEFKLQQTSCLKKDWKKPECTIKPNGRKRKCLACIKLDPKGKVLGRMVHCPILKQGPQVRRERG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0065008 (regulation of biological quality), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0014823 (response to activity), GO:0003008 (system process), GO:0009991 (response to extracellular stimulus), GO:1901698 (response to nitrogen compound), GO:0070887 (cellular response to chemical stimulus), GO:0071495 (cellular response to endogenous stimulus), GO:0008217 (regulation of blood pressure), GO:1901700 (response to oxygen-containing compound), GO:0003013 (circulatory system process), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0043434 (response to peptide hormone), GO:1901652 (response to peptide), GO:0071417 (cellular response to organonitrogen compound), GO:0032870 (cellular response to hormone stimulus), GO:0010243 (response to organonitrogen compound), GO:0008015 (blood circulation), GO:0071310 (cellular response to organic substance), GO:0003073 (regulation of systemic arterial blood pressure), GO:0031667 (response to nutrient levels), GO:1901699 (cellular response to nitrogen compound), GO:0045777 (positive regulation of blood pressure), GO:1901701 (cellular response to oxygen-containing compound), GO:1901653 (cellular response to peptide), GO:0003084 (positive regulation of systemic arterial blood pressure), GO:0071375 (cellular response to peptide hormone stimulus), GO:0032868 (response to insulin), GO:0032869 (cellular response to insulin stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005615 (extracellular space), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005576 (extracellular region), GO:0030141 (secretory granule), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)
Protein: RCG29282, isoform CRA_b (A6K8Z0)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR016135: Ubiquitin-conjugating enzyme/RWD-like (homologous_superfamily) [6-184]
- IPR050113: Ubiquitin-conjugating enzyme (family) [9-165]
- IPR000608: Ubiquitin-conjugating (UBC), catalytic core domain (domain) [8-174]
- IPR023313: Ubiquitin-conjugating enzyme, active site (active_site) [82-97]
Sequence:
MARPLVPSSQKALLLELKGLQEEPVEGFRVTLVDEGDLYNWEVAIFGPPNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKESKGKDREYTDIIRKQVLGTKVDAERDGVKVPTTLAEYCVKTKAPAPDEGSDLFYDDYYEDGEVEEADSCFGDEEDDSGTEES
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0019787 (ubiquitin-like protein transferase activity), GO:0061650 (ubiquitin-like protein conjugating enzyme activity), GO:0004842 (ubiquitin-protein transferase activity), GO:0061631 (ubiquitin conjugating enzyme activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0010942 (positive regulation of cell death), GO:0051130 (positive regulation of cellular component organization), GO:0051128 (regulation of cellular component organization), GO:0010941 (regulation of cell death), GO:0044089 (positive regulation of cellular component biogenesis), GO:0044087 (regulation of cellular component biogenesis), GO:0070848 (response to growth factor), GO:1901216 (positive regulation of neuron death), GO:1901214 (regulation of neuron death), GO:0090083 (regulation of inclusion body assembly), GO:0043067 (regulation of programmed cell death), GO:0043068 (positive regulation of programmed cell death), GO:0043065 (positive regulation of apoptotic process), GO:0042981 (regulation of apoptotic process), GO:0043525 (positive regulation of neuron apoptotic process), GO:0043523 (regulation of neuron apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:0140535 (intracellular protein-containing complex), GO:1990234 (transferase complex), GO:0000151 (ubiquitin ligase complex)
Protein: Galactokinase 1, isoform CRA_a (A6HKS9)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR020568: Ribosomal protein uS5 domain 2-type superfamily (homologous_superfamily) [6-214]
- IPR019741: Galactokinase, conserved site (conserved_site) [36-47]
- IPR006203: GHMP kinase, ATP-binding, conserved site (conserved_site) [133-144]
- IPR000705: Galactokinase (family) [36-142]
- IPR019539: Galactokinase, N-terminal domain (domain) [19-67]
- IPR006204: GHMP kinase N-terminal domain (domain) [108-193]
- IPR036554: GHMP kinase, C-terminal domain superfamily (homologous_superfamily) [218-260]
- IPR006206: Mevalonate/galactokinase (family) [6-253]
- IPR014721: Small ribosomal subunit protein uS5 domain 2-type fold, subgroup (homologous_superfamily) [3-217]
Sequence:
MAAWRPPRVEELLAEARRAFMEEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELVTVMVGSPRTDGLVSLLTTSKDADEPQRLQFPLPSAQWSLEPGIPQWANYVKGVIQYYPASPLCGFSAVVVSSVPLGGGLSSSASLEVATYAFLQQLCPDSGSIAARAQVCQRAEHSFAGVPCGIMDQLIALLGQKGYALLIDCRSLETSLVPLSDPKLTVLITNSNVRHSLASSEYPIRRRQCEEVAQALGKESLREVLSL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0036094 (small molecule binding), GO:0030246 (carbohydrate binding), GO:1901363 (heterocyclic compound binding), GO:0016740 (transferase activity), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0097367 (carbohydrate derivative binding), GO:0048029 (monosaccharide binding), GO:1901265 (nucleoside phosphate binding), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0043168 (anion binding), GO:0000166 (nucleotide binding), GO:0032553 (ribonucleotide binding), GO:0035639 (purine ribonucleoside triphosphate binding), GO:0016301 (kinase activity), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0005534 (galactose binding), GO:0032555 (purine ribonucleotide binding), GO:0017076 (purine nucleotide binding), GO:0005524 (ATP binding), GO:0019200 (carbohydrate kinase activity), GO:0032559 (adenyl ribonucleotide binding), GO:0030554 (adenyl nucleotide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0005996 (monosaccharide metabolic process), GO:0005975 (carbohydrate metabolic process), GO:0044262 (cellular carbohydrate metabolic process), GO:0006793 (phosphorus metabolic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0019318 (hexose metabolic process), GO:0046835 (carbohydrate phosphorylation), GO:0006012 (galactose metabolic process), GO:0016310 (phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm)