Protein: Protein tyrosine phosphatase, receptor type, K, extracellular region, isoform CRA_b (A6JPF0)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Single- pass type I membrane protein
InterPro domains:
- IPR029021: Protein-tyrosine phosphatase-like (homologous_superfamily) [873-975]
- IPR013098: Immunoglobulin I-set (domain) [200-277]
- IPR000998: MAM domain (domain) [30-193]
- IPR003961: Fibronectin type III (domain) [290-594]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [192-595]
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [289-589]
- IPR000242: Tyrosine-specific protein phosphatase, PTPase domain (domain) [899-960]
- IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [33-191]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [195-297]
- IPR007110: Immunoglobulin-like domain (domain) [195-280]
- IPR051622: Receptor-type Tyrosine-protein Phosphatases (family) [28-821]
- IPR057598: Receptor-type tyrosine-protein phosphatase U-like, Fn3 domain (domain) [589-733]
- IPR003599: Immunoglobulin domain subtype (domain) [200-288]
Sequence:
MDVAAAALPAFVALWLLSPWPLLGSVQGQFSAGGCTFDDGPGACDYHQDLYDDFEWVHVSAQEPHYLPPEMPQGSYMVVDSSNHDPGEKARLQLPTMKENDTHCIDFSYLLYSQKGLNPGTLNILVRVNKGPLANPIWNVTGFTGRDWLRAELAVSTFWPNEYQVIFEAEVSGGRSGYIAIDDIQVLSYPCDKSPHFLRLGDVEVNAGQNATFQCIATGRDAVHNKLWLQRRNGEDIPVAQTKNINHRRFAASFRLQEVTKTDQDLYRCVTQSERGSGVSNFAQLIVREPPRPIAPPQLLGVGPTYLLIQLNANSIIGDGPIILKEVEYRMTSGSWTETHAVNAPTYKLWHLDPDTEYEIRVLLTRPGEGGTGLPGPPLITRTKCAEPMRTPKTLKIAEIQARRIAVDWESLGYNITRCHTFNVTICYHYFRGHNESRADCLDMDPKAPQHVVNHLPPYTNVSLKMILTNPEGRKESEETIIQTDEDVPGPVPVKSLQGTSFENKIFLNWKEPLEPNGIITQYEVSYSSIRSFDPAVPVAGPPQTVSNLWNSTHHVFMHLHPGTTYQFFIRASTVKGFGPATAINVTTNISAPSLPDYEGVDASLNETATTITVLLRPAQAKGAPISAYQIVVEQLHPHRTKREAGTMECYRVPVTYQNSLSGGAPYYFAAELPPGNLPEPAPFTVGDNRTYKGFWNPPLAPRKGYNIYFQAMSSVEKETKTQCVRIATKAAATEEPEVIPDPAKQTDRVVKIAGISAGVLVFILLLLVVIVIVKKSKLAKKRKDAMGNTRQEMTHMVNAMDRSYADQSTLHAEDPLSLTFMDQHNFSPRLPNDPLVPTAVLDENHSATAESSRLLDVPRYLCEGTESPYQTGQLHPAIRVADLLQHINLMKTSDSYGFKEEYESFFEGQSASWDVAKKDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDNLLSYFRATRDQATTLQLKDQFMKPCMIFGEWYGRSSQPVS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0004721 (phosphoprotein phosphatase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0004725 (protein tyrosine phosphatase activity), GO:0016791 (phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0001775 (cell activation), GO:0045321 (leukocyte activation), GO:0007155 (cell adhesion), GO:0071840 (cellular component organization or biogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0016043 (cellular component organization), GO:0046649 (lymphocyte activation), GO:0030097 (hemopoiesis), GO:0022008 (neurogenesis), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0002521 (leukocyte differentiation), GO:0042110 (T cell activation), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0030098 (lymphocyte differentiation), GO:1903131 (mononuclear cell differentiation), GO:0031175 (neuron projection development), GO:0030217 (T cell differentiation), GO:0048699 (generation of neurons), GO:0120036 (plasma membrane bounded cell projection organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0098794 (postsynapse), GO:0071944 (cell periphery), GO:0045211 (postsynaptic membrane), GO:0098590 (plasma membrane region), GO:0045202 (synapse), GO:0005886 (plasma membrane), GO:0099572 (postsynaptic specialization), GO:0097060 (synaptic membrane), GO:0099634 (postsynaptic specialization membrane), GO:0098984 (neuron to neuron synapse), GO:0014069 (postsynaptic density), GO:0098978 (glutamatergic synapse), GO:0032279 (asymmetric synapse), GO:0098839 (postsynaptic density membrane)