Protein: Neurogenin 3 (F7EPK2)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR011598: Myc-type, basic helix-loop-helix (bHLH) domain (domain) [83-141]
- IPR032656: Neurogenin-3, basic helix-loop-helix domain (domain) [77-144]
- IPR050359: Basic helix-loop-helix transcription factors (family) [28-148]
- IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [81-144]
Sequence:
MAPHPLDAPTIQVSQETQQPFPGASDHEVLSSNSTPPSPTLVPRDCSEAEAGDCRGTSRKLRARRGGRNRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRIADHSFYGPEPPVPCGELGSPGGGSSGDWGSIYSPVSQAGSLSPTASLEEFPGLQVPSSPSCLLPGTLVFSDFL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0001216 (DNA-binding transcription activator activity), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific), GO:0003677 (DNA binding), GO:0001228 (DNA-binding transcription activator activity, RNA polymerase II-specific), GO:0003690 (double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0050793 (regulation of developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0051094 (positive regulation of developmental process), GO:0048522 (positive regulation of cellular process), GO:0045597 (positive regulation of cell differentiation), GO:0060322 (head development), GO:0030900 (forebrain development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0030902 (hindbrain development), GO:0060255 (regulation of macromolecule metabolic process), GO:0045595 (regulation of cell differentiation), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0007420 (brain development), GO:0045664 (regulation of neuron differentiation), GO:0021510 (spinal cord development), GO:0007399 (nervous system development), GO:0045666 (positive regulation of neuron differentiation), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0007417 (central nervous system development), GO:0051252 (regulation of RNA metabolic process), GO:0010468 (regulation of gene expression), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)