Protein: Calcium-activated chloride channel regulator 1 (A6HWA3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted, extracellular space
InterPro domains:
- IPR036465: von Willebrand factor A-like domain superfamily (homologous_superfamily) [308-477]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [751-862]
- IPR013642: Calcium-activated chloride channel, N-terminal (domain) [25-290]
- IPR051266: Calcium-activated chloride channel regulator (family) [156-861]
- IPR004727: Calcium-activated chloride channel protein, chordata (family) [1-859]
- IPR002035: von Willebrand factor, type A (domain) [305-478]
Sequence:
MGSLKSPVFLLVLYLLEGVLSNSLIQLNNNGYEGIVIAIDHDVPEDEALIQRIKDMVTQASPYLFEATGKRFYFKNVAILIPENWNTKPEYKRPKLETLKNADVLVSTMSPIGNDEPYTEHIGACGERGIRIHLTPDFLAGKKQTEYGPQDRTFVHEWAHFRWGVFDEYNNNEKFYLSNGKPQAVRCSATITGKHVVRRCQGGSCVTNGKCVIDRVTGLYKDNCVFIPDKNQREKASIMFNQNINSVVEFCTEKNHNKEAPNAQNQRCNLRSTWEVIQESEDFKQTTPMTAQPPAPTFSLLQTRQRIVCLVLDKSGSMQSDNRLNRMNQASRLFLLQTVEQGSWVGMVTFDSTAYVQSELTQLNSGADRDLLIKRLPTVASGGTSICSGLQAAFTSIKKKYPTDGAEIVLLTDGEDNTISSCFDLVKNSGAIIHTVALGPSAAKELEQLSKMTGGLQTYSSDQIQNNGLVDAFAALSSGNAAISQHSIQLESRGVNLQNKQWMNGSVIVDSTVGKDTLFLVTWTTNSPSIFIWDPSGVQQSGFVLDTNTKVAYLQVPGIAKVGFWKYSIQASSQTLTLTVTSRAASATLPPITVTPVVNKNTGKFPSPVTVYASIRQGASPILRASVTALIESVNGKTVTLELLDNGAGADATKNDGVYSRFFTAFDANGRYSIKIWALGGVTADRQRMAPQRNGVMYIDGWIEDDGEIKMNPPHPETGNVQDSQVCFSRTSSGGSFVATNVPAAPIPDLFPPCQITDLKASIQGQNLVNLTWTAPGDDYDHGRASSYIIRISTSIVDLRNNFSTSLEVNTTDLIPKEASSEEMFEFELDNSFGNGTDVFIAIQAVDKSNLKSEISNIARVSLFIPAQEPPEDSTPSYPEVSINSTIPGIHVLNIVWKWLGEMHVTLGLH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0005215 (transporter activity), GO:0016787 (hydrolase activity), GO:0022857 (transmembrane transporter activity), GO:0140096 (catalytic activity, acting on a protein), GO:0008233 (peptidase activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0008509 (monoatomic anion transmembrane transporter activity), GO:0008237 (metallopeptidase activity), GO:0015108 (chloride transmembrane transporter activity), GO:0015103 (inorganic anion transmembrane transporter activity), GO:0015267 (channel activity), GO:0004175 (endopeptidase activity), GO:0004222 (metalloendopeptidase activity), GO:0005253 (monoatomic anion channel activity), GO:0005254 (chloride channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0001666 (response to hypoxia), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0070482 (response to oxygen levels), GO:0071456 (cellular response to hypoxia), GO:0071453 (cellular response to oxygen levels), GO:0036293 (response to decreased oxygen levels), GO:0036294 (cellular response to decreased oxygen levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0030141 (secretory granule), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0030667 (secretory granule membrane), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0042588 (zymogen granule), GO:0098588 (bounding membrane of organelle), GO:0031982 (vesicle), GO:0012506 (vesicle membrane), GO:0030659 (cytoplasmic vesicle membrane), GO:0097708 (intracellular vesicle)