Protein: Stress-70 protein, mitochondrial (A0A7I2V3F7)
Organism: Homo sapiens (Human)
InterPro domains:
- IPR018181: Heat shock protein 70, conserved site (conserved_site) [58-255]
- IPR043129: ATPase, nucleotide binding domain (homologous_superfamily) [55-399]
- IPR013126: Heat shock protein 70 family (family) [55-397]
- IPR029048: Heat shock protein 70kD, C-terminal domain superfamily (homologous_superfamily) [477-580]
- IPR029047: Heat shock protein 70kD, peptide-binding domain superfamily (homologous_superfamily) [393-510]
Sequence:
MISASRAAAARLVGAAASRGPTAARHQDSWNGLSHEAFRLVSRRDYASEAIKGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAHGKLYSPSQIGAFVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKSEDKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQASLKLFEMAYKKMASEREGSGSSGTGEQKEDQKEEKQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0019899 (enzyme binding), GO:0051082 (unfolded protein binding), GO:0003723 (RNA binding), GO:0044389 (ubiquitin-like protein ligase binding), GO:0031625 (ubiquitin protein ligase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0042592 (homeostatic process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0050793 (regulation of developmental process), GO:0048856 (anatomical structure development), GO:0044237 (cellular metabolic process), GO:0050794 (regulation of cellular process), GO:0002682 (regulation of immune system process), GO:0071840 (cellular component organization or biogenesis), GO:0051239 (regulation of multicellular organismal process), GO:0051093 (negative regulation of developmental process), GO:0048871 (multicellular organismal-level homeostasis), GO:0002262 (myeloid cell homeostasis), GO:0048523 (negative regulation of cellular process), GO:2000026 (regulation of multicellular organismal development), GO:0044085 (cellular component biogenesis), GO:0060548 (negative regulation of cell death), GO:0034101 (erythrocyte homeostasis), GO:0010941 (regulation of cell death), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0045596 (negative regulation of cell differentiation), GO:0045595 (regulation of cell differentiation), GO:0016043 (cellular component organization), GO:1903706 (regulation of hemopoiesis), GO:0006790 (sulfur compound metabolic process), GO:0048872 (homeostasis of number of cells), GO:0045637 (regulation of myeloid cell differentiation), GO:0030097 (hemopoiesis), GO:0045638 (negative regulation of myeloid cell differentiation), GO:0030218 (erythrocyte differentiation), GO:0043069 (negative regulation of programmed cell death), GO:0043067 (regulation of programmed cell death), GO:0060284 (regulation of cell development), GO:0016226 (iron-sulfur cluster assembly), GO:0006996 (organelle organization), GO:0030099 (myeloid cell differentiation), GO:0061024 (membrane organization), GO:0022607 (cellular component assembly), GO:0007005 (mitochondrion organization), GO:0042981 (regulation of apoptotic process), GO:0007006 (mitochondrial membrane organization), GO:0043066 (negative regulation of apoptotic process), GO:0031163 (metallo-sulfur cluster assembly), GO:0045646 (regulation of erythrocyte differentiation), GO:0007007 (inner mitochondrial membrane organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)