Protein: 2'-5'-oligoadenylate synthetase 1 (A0A7P0Z444)
Organism: Homo sapiens (Human)
InterPro domains:
- IPR018952: 2'-5'-oligoadenylate synthetase 1, domain 2/C-terminal (domain) [164-302]
- IPR006116: 2-5OAS/ClassI-CCAase, nucleotidyltransferase domain (domain) [29-211]
- IPR043518: 2-5-oligoadenylate synthetase, N-terminal conserved site (conserved_site) [62-81]
- IPR002934: Polymerase, nucleotidyl transferase domain (domain) [38-112]
- IPR043519: Nucleotidyltransferase superfamily (homologous_superfamily) [1-201]
Sequence:
MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDLQKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPPQYALELLTVYAWERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPSTLQAASTPQAEEDWTCTIL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003725 (double-stranded RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:0048584 (positive regulation of response to stimulus), GO:0009607 (response to biotic stimulus), GO:0006955 (immune response), GO:0002684 (positive regulation of immune system process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0051716 (cellular response to stimulus), GO:0002682 (regulation of immune system process), GO:0006950 (response to stress), GO:0002253 (activation of immune response), GO:0051707 (response to other organism), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0002764 (immune response-regulating signaling pathway), GO:0002831 (regulation of response to biotic stimulus), GO:0032103 (positive regulation of response to external stimulus), GO:0050776 (regulation of immune response), GO:0043207 (response to external biotic stimulus), GO:0002757 (immune response-activating signaling pathway), GO:1901698 (response to nitrogen compound), GO:0002833 (positive regulation of response to biotic stimulus), GO:0080134 (regulation of response to stress), GO:0006952 (defense response), GO:0050778 (positive regulation of immune response), GO:0032101 (regulation of response to external stimulus), GO:0031349 (positive regulation of defense response), GO:0030522 (intracellular receptor signaling pathway), GO:0009615 (response to virus), GO:0010033 (response to organic substance), GO:0002218 (activation of innate immune response), GO:0098542 (defense response to other organism), GO:0031347 (regulation of defense response), GO:0045089 (positive regulation of innate immune response), GO:0002758 (innate immune response-activating signaling pathway), GO:0045088 (regulation of innate immune response), GO:0140546 (defense response to symbiont), GO:0051607 (defense response to virus), GO:0043331 (response to dsRNA), GO:0002753 (cytosolic pattern recognition receptor signaling pathway), GO:0014070 (response to organic cyclic compound), GO:0002221 (pattern recognition receptor signaling pathway), GO:0043330 (response to exogenous dsRNA)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)