Protein: Serine/threonine-protein kinase receptor (A0A8M9PJN6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Single-pass type I membrane protein
InterPro domains:
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [324-336]
- IPR000472: Activin types I and II receptor domain (domain) [28-101]
- IPR001245: Serine-threonine/tyrosine-protein kinase, catalytic domain (domain) [200-485]
- IPR000719: Protein kinase domain (domain) [200-490]
- IPR003605: GS domain (domain) [170-200]
- IPR000333: Ser/Thr protein kinase, TGFB receptor (family) [26-494]
- IPR017441: Protein kinase, ATP binding site (binding_site) [206-227]
- IPR045860: Snake toxin-like superfamily (homologous_superfamily) [26-122]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [176-487]
Sequence:
MLLRNSGKVEERRETGSDAPALPQRFLWCYCYHHCPEDSTNNTCRTDGYCFTMVEEEGGAAVVTSGCLGLVGSEFQCRDTGNSKQRRALECCTDQDYCNRDLHPTLPPLRTPSYVVGDIHHIALLISVSVCSFILTFIIIFCYFRYKRHELAPRYSLGLHPDESFIPAGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVTQIGKGRYGEVWMGRWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHDNILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKCTTLDSRAMLKLAYSSVSGLCHLHTEIFGTQGKPAIAHRDLKSKNILVKRNGACCIADLGLAVKFISDTNEVDIPLNTRVGTKRFMAPEVLDETLNRNHFQSYIMADMYSFGLILWEISRRCVTGGIVEEYQLPYHDHVPNDPSYEDMREVVCIKRIRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTLAKMSESQDIKV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0051716 (cellular response to stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009719 (response to endogenous stimulus), GO:0007154 (cell communication), GO:0007389 (pattern specification process), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0009799 (specification of symmetry), GO:0071495 (cellular response to endogenous stimulus), GO:0007166 (cell surface receptor signaling pathway), GO:0003002 (regionalization), GO:0070848 (response to growth factor), GO:0009855 (determination of bilateral symmetry), GO:0009953 (dorsal/ventral pattern formation), GO:0007167 (enzyme-linked receptor protein signaling pathway), GO:0071772 (response to BMP), GO:0071363 (cellular response to growth factor stimulus), GO:0007178 (transmembrane receptor protein serine/threonine kinase signaling pathway), GO:0048262 (determination of dorsal/ventral asymmetry), GO:0071773 (cellular response to BMP stimulus), GO:0048263 (determination of dorsal identity), GO:0030509 (BMP signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0043235 (receptor complex), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:0098802 (plasma membrane signaling receptor complex), GO:0098797 (plasma membrane protein complex), GO:0005886 (plasma membrane)