Protein: Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor (Predicted) (A6JYS8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Single- pass type I membrane protein
InterPro domains:
- IPR000152: EGF-type aspartate/asparagine hydroxylation site (ptm) [387-437]
- IPR000742: EGF-like domain (domain) [82-771]
- IPR002172: Low-density lipoprotein (LDL) receptor class A repeat (repeat) [42-373]
- IPR000033: LDLR class B repeat (repeat) [478-715]
- IPR049883: NOTCH1 EGF-like calcium-binding domain (domain) [412-450]
- IPR036055: LDL receptor-like superfamily (homologous_superfamily) [41-371]
- IPR023415: Low-density lipoprotein (LDL) receptor class A, conserved site (conserved_site) [95-371]
- IPR018097: EGF-like calcium-binding, conserved site (conserved_site) [412-435]
- IPR051221: Low-density lipoprotein receptor-related (family) [40-777]
- IPR001881: EGF-like calcium-binding domain (domain) [372-451]
- IPR011042: Six-bladed beta-propeller, TolB-like (homologous_superfamily) [458-718]
Sequence:
MGRPERGALRPLALLLLLLLLLLQLQHLSTADPLPGGQGPVKECEEDQFRCRNERCIPSVWRCDEDNDCSDNSDEDDCPKRTCTDSDFTCDNGHCIPERWKCDGEEECPDGSDESKATCSSEECPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGCPTLCAPHEFQCSNRSCLASVFVCDGDDDCGDGSDERGCSDPACPPREFRCGGGGTCIPERWVCDGQFDCEDRSDEAAELCGRAGQGTTATPAACAPTTQFTCRSGECIHLGWRCDGDRDCKDKSDEADCSPGPCRENDFQCGDGTCILAIKRCNQERDCLDGSDEAGCLQESTCEGPRRFQCKSGECVDGGKVCDDQRDCRDWSDEPQKVCGLNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECQDPDACSQICVNYKGYFKCECHPGYEMDTLTKNCKAVAGRSPSLIFTNRHEVRRIDLVKRDYSRLIPMLKNVVALDVEVDTNRIYWCDLSYRKIYSAHMDKASIPDEQVVLIGEQLHSPEGLAVDWVHKHIYWTDSGNKTVSVATTDGRRRCTLFNRDLSEPRAIAVDPLRGFMYWSDWGFQAKIEKAGLNGADRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFNGGNRKMLIFSTDFLSHPFGVAVFEDKVFWTDLENEAIFSANRLNGLEISILAENLNNPHDIVIFHELKQPKAADACELSAQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRCYRAPPSTSTTTLASAMTRTVPATTGAPGTTIHDSTYQNHSTEMPSQTAAVPHSVNIPKAHSTSPSTLSPATSNHSQHYGNEGSQMGSTVTAAVIGIIVPIVVIALLCMSGYLIWRNWKRKNTKSMNFDNPVYRKTTEEEEEDELHIGRTAQIGHVYPAAISSYDRPLWAEPCLGETRDLEDPAPAHKELFVLPGEPRSQLHQLPKNPLSELPVVKCKLSLFYNPLQLNDQDNYDTSVFGLSGGRLMSKF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0071814 (protein-lipid complex binding), GO:0071813 (lipoprotein particle binding), GO:0019894 (kinesin binding), GO:0008035 (high-density lipoprotein particle binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0051716 (cellular response to stimulus), GO:0021987 (cerebral cortex development), GO:0021537 (telencephalon development), GO:0060322 (head development), GO:0009410 (response to xenobiotic stimulus), GO:0070887 (cellular response to chemical stimulus), GO:0030900 (forebrain development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0070848 (response to growth factor), GO:0021543 (pallium development), GO:0071495 (cellular response to endogenous stimulus), GO:1901700 (response to oxygen-containing compound), GO:0010033 (response to organic substance), GO:0007420 (brain development), GO:0097305 (response to alcohol), GO:0007399 (nervous system development), GO:0036314 (response to sterol), GO:0071310 (cellular response to organic substance), GO:0033993 (response to lipid), GO:0007417 (central nervous system development), GO:0014070 (response to organic cyclic compound), GO:1901701 (cellular response to oxygen-containing compound), GO:0071363 (cellular response to growth factor stimulus), GO:0036315 (cellular response to sterol), GO:0070723 (response to cholesterol), GO:0097306 (cellular response to alcohol), GO:0071407 (cellular response to organic cyclic compound), GO:0071396 (cellular response to lipid), GO:0071397 (cellular response to cholesterol)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005875 (microtubule associated complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0098794 (postsynapse), GO:0044297 (cell body), GO:0036477 (somatodendritic compartment), GO:0030054 (cell junction), GO:0043025 (neuronal cell body), GO:0120025 (plasma membrane bounded cell projection), GO:0097447 (dendritic tree), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0099572 (postsynaptic specialization), GO:0043228 (non-membrane-bounded organelle), GO:0043005 (neuron projection), GO:0098984 (neuron to neuron synapse), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0014069 (postsynaptic density), GO:0030425 (dendrite), GO:0005856 (cytoskeleton), GO:0032279 (asymmetric synapse), GO:0030424 (axon), GO:0015630 (microtubule cytoskeleton)