Protein: Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform X2 (A0A2R8QSP1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR042133: Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain (domain) [1422-1530]
- IPR001683: Phox homology (domain) [1418-1534]
- IPR036940: Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily (homologous_superfamily) [1185-1382]
- IPR001263: Phosphoinositide 3-kinase, accessory (PIK) domain (domain) [857-1043]
- IPR002420: C2 phosphatidylinositol 3-kinase-type domain (domain) [672-838]
- IPR000008: C2 domain (domain) [683-1679]
- IPR000403: Phosphatidylinositol 3-/4-kinase, catalytic domain (domain) [1101-1392]
- IPR018936: Phosphatidylinositol 3-/4-kinase, conserved site (conserved_site) [1133-1251]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [1040-1387]
- IPR036871: PX domain superfamily (homologous_superfamily) [1399-1541]
- IPR029071: Ubiquitin-like domain superfamily (homologous_superfamily) [351-519]
- IPR016024: Armadillo-type fold (homologous_superfamily) [863-1035]
- IPR015433: Phosphatidylinositol 3-/4-kinase (family) [208-1391]
- IPR042236: Phosphoinositide 3-kinase, accessory (PIK) domain superfamily (homologous_superfamily) [851-1034]
- IPR000341: Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain (domain) [407-511]
- IPR035892: C2 domain superfamily (homologous_superfamily) [680-1683]
Sequence:
MAHISSGNGFKFDRPASPGVVRPKGIVGKEEALRMEVEAFDKIKREKRHTLPVTASSVNPLPNPTAQTSTSRPEKDLIVFCESETQKKEQKDNFEDIDLENLTKEELEKLLLDDSFGANKMTRPSSLLGCNLSASYPGGHAFNPSSFHWTPTPTHAQTPIFPSAPFAKPPCSFQNGFSPAMSPFIPPTPFLSFTPIQPPAALVYSQPAVTPEMAKLFDKIASTSEYLKNGRSSSMETESASVKSLEPLPQPSEPPNISRFEWLDLDPLNKRKEVEVEETPAVSSCPFIEESGKAKDPWDAVLQDEHETVDNGSPKAEEKCKATQPRRASTGAAVTKSQSLSISSNSTNQSTGKQVNKGSTNVLSKYSALQEKEAQNLEVVAFCEDISKLRSKFPHDDLSTNPGYVLSPVITQRDAGGDNGGSVKVSIEISDSQQPVTFTCDVTSPVDLLIMQALCWVHDDLNQVDINSYVLKVCGQEEVLQNKHSLGSHEYVQNCRKWESEIKLQLLFLSTMRRDLARTAEDDISPIDLEKYLGLVERPFKEAVTREGLAEYLEGFHKQVNLCLQNENNQYKTVDNVVQSVKNLCCALDEVETPAITDAVKRLKRSVNLPRTRSPEAGATSSGGSANGYSSPVEESLAVLTDAVYELAKLYLQSFCPISPGFMIEEHKEDERDSKEASGTTEHLQFTLFAVHGIPATWVSSFEKYYLMCALTHNNRNLFKPVQSKKVGTYKSFFYHIKWDELINFPISVSLLPLEAMLSLSLYGVLSQNANNSPDSNKQRKGPELLGKVSMPLFDFRRVLSRGSKLLSLWTSPQALQPGAAGKGRNPTEKIILQVDFPSPAVDVLYVGPQENGCPNPQSLDPLDQDDRSEIEKLCARASTFGLSRADRQLLWDQRYYCREYEYSLPKILASAPSWDWGSMGEIHALLHHWPALSPVSALELLESKFADTEVRKVAVSWIQSSSDDELADYLPQLVQAVKFECHLKNALVKFLLSRALGNVNIAHYLYWLLRDAVQDPAFGQRYERILCVLLCLCGTGLRAELEKQTRLVQLLGALAEKVRQASSSTRQVVLLEGLERVQSFFQKNSCRLPISPSLVAKELNIKVCSFFNSNAVPLKIALVNADPLGDEINVMFKVGEDLRQDMLALQMIRIMDRIWLQEGLDLRIVNFKCISTGKDKGMVELVPSSETLRKIQVEYGVTGSFKDKPLAEWLRKYNPAEDEYEKASENFIYTCAGCCVATYILGICDRHNDNIMLRSTGHMFHIDFGKFLGHAQMIGSFKRDRAPFVLTSDMAYVINGGERPTSRFQLFVDLCSQAYNLIRKHSNLFLNLLSLMTQSGLPELTGVQDLKYVYDALQPQTTDAEATIFFTRLIESSLGSVATKFNFFIHNLAQLRFSGLPSNDEPILSFAPRTYTMKQDGKIRDASVFSYQKRYNPDKHYTYVIRILREGQSEPQFVFRTFDEFQELHNKLTILFQLWKLPGFPSKMVLGRTHIKDVASKRKVELNSYVHNLMRSSTEVAQCDLIYTFFHPIARDDKTEGVDTLSKTPDMPPVSPTTGRVEGEVKLSVSYRNSTLFIMVMHIKDLMSNDGADPNPYVKTYLLPDPHKTSKRKTKIARKTRNPTFNEMLVYSGYSKETLKQRELQLSVLSAESLRENCYLGGITLCLKDFDLSRETVKWYKLTTVPYF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0016301 (kinase activity), GO:0052742 (phosphatidylinositol kinase activity), GO:0035004 (phosphatidylinositol 3-kinase activity), GO:0016303 (1-phosphatidylinositol-3-kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0035239 (tube morphogenesis), GO:0048514 (blood vessel morphogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)