Protein: RCG31986 (A6KDN7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
- IPR003593: AAA+ ATPase domain (domain) [925-2123]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [889-2148]
- IPR026082: ABC transporter A (family) [1891-2229]
- IPR017871: ABC transporter-like, conserved site (conserved_site) [1033-1047]
- IPR056264: ABCA1-4-like, C-terminal R2 regulatory domain (domain) [2136-2210]
- IPR013525: ABC-2 type transporter, transmembrane domain (domain) [640-1868]
- IPR003439: ABC transporter-like, ATP-binding domain (domain) [899-2144]
Sequence:
MACWSQLRLLLWKNLTFRRRQTCQLLLEVAWPLFIFLILISVRLSYPPYEQHECHFPNKAMPSAGTLPWVQGIICNANNPCFRYPTPGEAPGVVGNFNKSIVSRLFSDAQRILLYSQKDTSIRDMHKVLRTLQQIKHPNSNLKLQDFLVDNETFSGFLQHSLSLPRSAVDNLLQADVSLQKVFLQGYQLHLASLCNGSKLEEIIRLGDLEVSALCSLPREKLDAAERELRSNMDILKPVMTKLNSTSLLPTQHLAEATTTLLDSLGGLAQELFSTKSWSDMRQEVMFLTNVNNSGSSTQIYQAVSRIVCGHPEGGGLKIKSLNWYEDNNYKALFGGNGTEEDTDTFYDNSTTPYCNDLMKNLESSPLSRIIWKALKPLLIGKILYTPDTPATRQVMAEVNKTFQELALFHDLEGMWEELSPQIWTFMESSQEMDLVRTMLDSRGNDQFWERKLDGLDWTAQDIMAFLAKNPEDVQSPNGSVYTWREAFNETNQAIQTISRFMECVNLNKLEPIPTEVRLINKSMELLDERKFWAGIVFTGITPDSVELPHHVKYKIRMDIDNVERTNKIKDGYWDPGPRADPFEDMRYVWGGFAYLQDVVEQAIIRVLTGTEKKTGVYVQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKSIVYEKEARLKETMRIMGLDNGILWFSWFISSLIPLLVSAGLLVIILKLGDLLPYSDPSVVFVFLSVFAVVTILQCFLISTLFSRTNLAAACGGIIYFTLYLPYVLCVAWQDYVGFSIKIFASLLSPVAFGFGCEYFALFEEQGIGVQWDNLFKSPVEEDGFNLTTSVSMMLFDTFIYGVMTWYIEAVFPGQYGIPRPWYFPCTKSYWFGEEIDEKSHPGSSQKGASEICMEEEPTHLKLGVSIQNLVKVYRDGMKVAVDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMNSIRQNLGVCPQHNVLFDMLTVEEHIWFYARLKGLSEKHVKAEMEQMALDVGLPPSKLKSKTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQGRTIILSTHHMDEADILGDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVESSLSSCRNSSSTVSCLKKEDSVSQSSSDAGLGSDHESDTLTIDVSAISNLIRKHVSEARLVEDIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGISETTLEEIFLKVAEESGVDAETSDGTLPARRNRRAFGDKQSCLHPFTEDDAVDPNDSDLDPESRETDLLSGMDGKGSYQLKGWKLTQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPNLELQPWMYNEQYTFVSNDAPEDMGTQELLNALTKDPGFGTRCMEGNPIPNTPCLVGEEDWTTGPVPQTLMDLFQNGNWTMKNPSPSCQCSSDKIKKMLPVCPPGAGGLPPPQRKQKTADILQNLTGRNISDYLVKTYVQIIAKSLKNKVWVNEFRYGGFSLGVSDSQALPPSQEVNNAIKQMKKLLKLTKDSSADRFLSSLGRFMTGLDTKNNVKVWFNNKGWHAISSFLNVINNAILRANLQKGENPSQYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHLQFICGVKPVIYWLSNFVWDMCNYVVPATLVVIIFICFQQKSYVSSTNLPVLALLLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVLELFTNNKFNDINDILKSVFLIFPHFCLGRGLIDMVKNQAMADALERFGENRFVSPLSWDLVGRNLFAMAVEGVVFFLVTVLIQYRFFIRPRPVKARLPPLNDEDEDVRRERQRILEGGGQNDILEIKELTKIYRRKRKPAVDRICVGIPPGECFGLLGVNGAGKTSTFKMLTGDTAVTRGDALLNKNSILSNIHEVHQNMGYCPQFDAITELLTGREHLEFFALLRGVPEKEVGKVGEWAIRKLGLVKYGEKYASNYSGGNKRKLSTAIALIGGPPVVFLDEPTTGMDPKARRFLWNCALSIIKEGRSVVLTSHSMEECEALCTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRIAGSNPDLKPVQEFFGLAFPGSVLKEKHRNMLQYQLPSSLSSLARIFSILSQSKKRLHIEDYSVSQTTLDQVFVNFAKDQSDDDHLKDLSLHKNQTVVDVAVLTSFLQDEKVKESYV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0140657 (ATP-dependent activity), GO:0044877 (protein-containing complex binding), GO:0042626 (ATPase-coupled transmembrane transporter activity), GO:0022857 (transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0071814 (protein-lipid complex binding), GO:0015399 (primary active transmembrane transporter activity), GO:0071813 (lipoprotein particle binding), GO:0008035 (high-density lipoprotein particle binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0006807 (nitrogen compound metabolic process), GO:0051234 (establishment of localization), GO:0051716 (cellular response to stimulus), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0033036 (macromolecule localization), GO:0010876 (lipid localization), GO:0009991 (response to extracellular stimulus), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0007584 (response to nutrient), GO:0009410 (response to xenobiotic stimulus), GO:0070887 (cellular response to chemical stimulus), GO:0006810 (transport), GO:0019538 (protein metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901700 (response to oxygen-containing compound), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0010033 (response to organic substance), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006869 (lipid transport), GO:0009059 (macromolecule biosynthetic process), GO:0034097 (response to cytokine), GO:0097305 (response to alcohol), GO:0071466 (cellular response to xenobiotic stimulus), GO:0036314 (response to sterol), GO:0071310 (cellular response to organic substance), GO:0033993 (response to lipid), GO:0031667 (response to nutrient levels), GO:0071702 (organic substance transport), GO:0034645 (cellular macromolecule biosynthetic process), GO:0014070 (response to organic cyclic compound), GO:0042157 (lipoprotein metabolic process), GO:1901701 (cellular response to oxygen-containing compound), GO:0015914 (phospholipid transport), GO:0015850 (organic hydroxy compound transport), GO:0015748 (organophosphate ester transport), GO:0036315 (cellular response to sterol), GO:0070723 (response to cholesterol), GO:0097306 (cellular response to alcohol), GO:0015918 (sterol transport), GO:0071407 (cellular response to organic cyclic compound), GO:0071345 (cellular response to cytokine stimulus), GO:0071396 (cellular response to lipid), GO:0042158 (lipoprotein biosynthetic process), GO:0071397 (cellular response to cholesterol), GO:0030301 (cholesterol transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0045178 (basal part of cell), GO:0009986 (cell surface), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0009925 (basal plasma membrane), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0016323 (basolateral plasma membrane)