lokahq/bioreason-rl huggingface dataset:
Protein: RCG49590 (A6J2Q3)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR000719: Protein kinase domain (domain) [356-616]
- IPR000270: PB1 domain (domain) [43-122]
- IPR034879: Mitogen-activated protein kinase kinase kinase 2/3, PB1 domain (domain) [44-122]
- IPR053793: PB1-like domain (domain) [43-122]
- IPR017441: Protein kinase, ATP binding site (binding_site) [362-385]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [353-617]
Sequence:
MDDQQALNSIMQDLAVLHKASRPALSLQETRKAKPSSPKKQNDVRVKFEHRGEKRILQVTRPVKLEDLRSKSKIAFGQSMDLHYTNNELVIPLTTQDDLDKAVELLDRSIHMKSLKILLVLNGSTQATNLEPSPSPDDLNNTPLGAERKKRLSVVGPPNRDRSSPPPGYIPDELHQIARNGSFTSINSEGEFIPESMDQMLDPLSLSSPENSGSGSCPSLDSPLDGESYPKSRMPRAQSYPDNHQEFSDYDNPIFEKFGKGGTYPRRYHVSYHHQEYNDGRKTFPRARRTQGTSFRSPVSFSPTDHSLSTSSGSSIFTPEYEDSRIRRRGSDIDNPTLTVTDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFNPDSPETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNIKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLPPHVSDYTRDFLKRIFVEAKLRPSAEELLRHLFVHCH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity), GO:0004709 (MAP kinase kinase kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0006793 (phosphorus metabolic process), GO:0036211 (protein modification process), GO:0006796 (phosphate-containing compound metabolic process), GO:0043412 (macromolecule modification), GO:0006468 (protein phosphorylation), GO:0016310 (phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Telomeric repeat-binding factor (A6IYZ2)
Organism: Rattus norvegicus (Rat)
Function: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat
Subcellular location: Chromosome, telomere. Nucleus
InterPro domains:
- IPR001005: SANT/Myb domain (domain) [439-494]
- IPR030657: Telomeric repeat-binding factor 2 (family) [38-497]
- IPR031902: Telomeric repeat-binding factor 2, Rap1-binding domain (domain) [273-314]
- IPR017357: Telomeric repeat-binding factor 1/2 (family) [51-496]
- IPR036507: Telomere repeat-binding factor, dimerisation domain superfamily (homologous_superfamily) [45-244]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [445-495]
- IPR013867: Telomere repeat-binding factor, dimerisation domain (domain) [54-248]
- IPR017930: Myb domain (domain) [443-496]
Sequence:
MAGGGGSSDNGGRAANRRASRSGGRARRGRHEPGLGGAAERGAGEARLEEAVNRWVLKFYFHEALRAFRSSRYRDFRQIRDIMQALLVRPLGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTDSMVESSRRLVKEAAVIICIKNKEFEKASKILKKYMSKDPTTQKVRTDLLNIIREKNLAHPVIQNFSYEIFQQKMLRFLESHLDDTEPYLLTMAKKALRSESAASSTMKEEKHTEPVEKPLREPPRQPRNPPTTIGLRTVKAAFKALSTAQDSEAAFAKLDQKDLVLPNLASPSSPTHKNKRPRKDENESSAPAEGEGGSERQPRNNRMTISRLVLEEDSQSSEPSPDLNSSRQALSASPSKPRALNQPHTGEKNPKASKDKWNSPNGLEEKEVWSEEDQLFEVRAPGEDKSSNLARKQKWTIEESEWVKDGVQKYGEGNWVAISKSYPFVNRTAVMIKDRWRTMKKLGLN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0031503 (protein-containing complex localization), GO:0007017 (microtubule-based process), GO:0007018 (microtubule-based movement), GO:0051649 (establishment of localization in cell), GO:0046907 (intracellular transport), GO:0006810 (transport), GO:0010970 (transport along microtubule), GO:0099111 (microtubule-based transport), GO:0030705 (cytoskeleton-dependent intracellular transport), GO:0008088 (axo-dendritic transport), GO:0098930 (axonal transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0098687 (chromosomal region), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000781 (chromosome, telomeric region), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005694 (chromosome), GO:0005634 (nucleus), GO:0043073 (germ cell nucleus), GO:0001673 (male germ cell nucleus)
Protein: Interferon (Alpha and beta) receptor 1 (Predicted), isoform CRA_a (A6JLF6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Endosome. Lysosome
InterPro domains:
- IPR003961: Fibronectin type III (domain) [20-428]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [26-432]
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [28-426]
- IPR015373: Interferon/interleukin receptor domain (domain) [127-425]
- IPR050650: Type II Cytokine and Tissue Factor Receptors (family) [18-223]
Sequence:
MLAVVGAAALVLVAGAPWMLPVASGEDNLRPPEDVAIYIIDDNYTLKWNHHRESMGNVTFSAEYQKGEGRIWLKVPKCQHITRTKCEFSLLGINVYSKTQFRVRAEEGNSTSSWNEADSFIPFYKAHVSPPRVHLKAEDKAILVYISPPGEDGTMWAQEKRCFNYTIRIWGRSFPVREIKPMYFPKKISKLLPETTYCLEVRAVHTSLQRHSNYSSARCINTTVANKIPVPENLEVDVQGDSYVLKWDHAFANMTFKAQWIPVYSKSSPGNHSDKWKPIPTCANVQTTHCVSPRETFHTGTFFLRVQASDGNNTSFWSEEKLIDSQKYTLLPPPVIAVTPTGDSLLVYVSCKDSKCNGLIYEVIFWENTSNTEKRQHPQSMIKEHPEFNVVNLRPLTVYCVQARVLSTGVWNKTSKFSDKLCKKTHPGNSSVTWIITGFGALLFSAMAFYAGRSLQKYLYYVFSPPLKPPCSIDEFFSELPSKSLLLLTAEEHTERCFVIENTGVVAGEENRAPEEELRKYSSQSSQDSGNYSNEEEESVGPESGQDMLSTAPSGSPWSLPCPAGTLEDGACFPGKEKHLQSPVLRTQPALHG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0140375 (immune receptor activity), GO:0004896 (cytokine receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007166 (cell surface receptor signaling pathway), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0034097 (response to cytokine), GO:0071310 (cellular response to organic substance), GO:0019221 (cytokine-mediated signaling pathway), GO:0071345 (cellular response to cytokine stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Centrin 2, isoform CRA_b (A6KSY5)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR011992: EF-hand domain pair (homologous_superfamily) [15-175]
- IPR000629: ATP-dependent RNA helicase DEAD-box, conserved site (conserved_site) [151-159]
- IPR002048: EF-hand domain (domain) [34-178]
- IPR050145: Centrin/CML-like (family) [32-172]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [47-168]
Sequence:
MELCSGRASNFKKTNMASSAQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDMKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0043169 (cation binding), GO:0008092 (cytoskeletal protein binding), GO:0046872 (metal ion binding), GO:0015631 (tubulin binding), GO:0005509 (calcium ion binding), GO:0008017 (microtubule binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0019953 (sexual reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0007276 (gamete generation), GO:0007283 (spermatogenesis), GO:0048232 (male gamete generation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0005813 (centrosome), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015630 (microtubule cytoskeleton)
Protein: RCG30465, isoform CRA_a (A6JFP4)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR023362: PH-BEACH domain (domain) [172-269]
- IPR000409: BEACH domain (domain) [273-558]
- IPR036372: BEACH domain superfamily (homologous_superfamily) [266-558]
- IPR050865: BEACH Domain-Containing (family) [160-566]
- IPR004182: GRAM domain (domain) [159-276]
- IPR057496: FAN-like, N-terminal PH domain (domain) [3-151]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [176-266]
Sequence:
MLRFSLLLLNLEEYYFEQHTAFHVQHQGSPEERKIRGSLKICSKSVIFEPDAISQPILKIPLRDCLKIGKHGENGANKHFAKAKSLGISLIFSQVYFIKEHNIVAPYKIERGKMEYVFQLEVSGKVEDVVETLLQLHRASCLDKLGDQMAMITAILQSRLARTSFDKNRFQSVSEKLHMECKAEMVTPLVTNPGHVCITDTNLYFQPLNGYPKPVVQITLQDVRRIYKRRHGLMPLGLEVFCTEDDLCSDIYLKFYEPQDRDDLYFYIATYLEHHVAEHTAESYMLQWQRGHLSNYQYLLHLNNLADRSCNDLSQYPVFPWVISDYSSPELDLSNPATFRDLSKPVGALNPERLERLLTRYQEMPEPKFMYGSHYSSPGYVLFYLVRIAPEYMLCLQNGRFDNADRMFNSIAETWKNCLDGATDFKELIPEFYDEDASFLINSLKLDLGKRQGGQMVDDVELPAWASSPQDFLQKNKDALESSYVSEHLHEWIDLIFGYKQKGSEAIGAHNVFHPLTYEGGVDLNSIEDPDDKVAMLTQILEFGQTPKQLFVTPHPRRITPKFKSLSQASSYNASMTDSPVSPGEESLKT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0008047 (enzyme activator activity), GO:0060229 (lipase activator activity), GO:0016004 (phospholipase activator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0010941 (regulation of cell death), GO:0010942 (positive regulation of cell death), GO:0043067 (regulation of programmed cell death), GO:0043068 (positive regulation of programmed cell death), GO:0043065 (positive regulation of apoptotic process), GO:0042981 (regulation of apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Epidermal growth factor receptor pathway substrate 15, isoform CRA_b (A6JYY0)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR011992: EF-hand domain pair (homologous_superfamily) [66-158]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [84-96]
- IPR000261: EH domain (domain) [1-166]
- IPR002048: EF-hand domain (domain) [71-106]
Sequence:
MFLVYCALEKEPVPMSLPPALVPPSKRKTVSISGSMWAIPSSAAKESYHSLPPVGISPTKAPLRQWVVSPAEKAKYDEIFLKTDKDMDGYVSGLEVRETFLKTGLPSTLLAHIWALCDTKNCGKLSKDQFALAFHLINQKLIKGIDPPHSLTPEMIPPSDKSSLQKNTIGSSPVADFSAIKELDTLNNEIIDLQREKNNVEQDLKEKEDTVRQRTTEAQDLQDEVQRESLNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAEITSQESQISTYEEELSKAREELSRLQQETAQLEESVESGKAQLEPLQQHLQDSQQEISSMQMRLAMKDLETDNNQSNWCSSPQSILVNGAADYCSLSTSSSETANLNEHAEGQNNLESEPIHPESSVILSRMILLEKLIHLVVILSKVQTHLHLIASLNRLLLILLPLQVLTLSVHPAIAVIHRHRPFCFCFWK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0051641 (cellular localization), GO:0065008 (regulation of biological quality), GO:0023056 (positive regulation of signaling), GO:0031503 (protein-containing complex localization), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0051234 (establishment of localization), GO:0009893 (positive regulation of metabolic process), GO:0023051 (regulation of signaling), GO:0048522 (positive regulation of cellular process), GO:0042127 (regulation of cell population proliferation), GO:0046907 (intracellular transport), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0001919 (regulation of receptor recycling), GO:0006810 (transport), GO:0051649 (establishment of localization in cell), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0099072 (regulation of postsynaptic membrane neurotransmitter receptor levels), GO:0051668 (localization within membrane), GO:0001921 (positive regulation of receptor recycling), GO:0016197 (endosomal transport), GO:0098876 (vesicle-mediated transport to the plasma membrane), GO:0016192 (vesicle-mediated transport), GO:0006897 (endocytosis), GO:0099003 (vesicle-mediated transport in synapse), GO:0032456 (endocytic recycling), GO:0006898 (receptor-mediated endocytosis), GO:0031623 (receptor internalization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: RNA helicase (A6IKS3)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR001650: Helicase, C-terminal domain-like (domain) [230-424]
- IPR050079: DEAD box RNA helicase (family) [4-532]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [2-423]
- IPR011545: DEAD/DEAH-box helicase domain (domain) [32-206]
- IPR014014: RNA helicase, DEAD-box type, Q motif (domain) [7-35]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [26-234]
Sequence:
MEDQEALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQLLLHKKATGPVMEQAVRGLVLVPTKELARQAQSMIQQLASYCARDVRVANVSAAEDSASQRAVLMEKPDVVVGTPSRILNHLQQKNLKLRDSLELLVVDEADLLFSFGFEDELKSLLCHLPRIYQAFLMSATFNEDVQTLKELVLHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFLLLYALLKLSLIRGKALLFVNTLERGYRLRLFLEQFSIPSCVLNGELPLRSRCHIISQFNQGLYDCVIATDAEILGPQVKAKRQGRGSKGDKASDPESGVARGIDFHHVSAVLNFDLPPTAEAYVHRAGRTARANNPGIVLTFVLPTEQSSLGKIEELLSGEGQAPILLPYQFQMEEIESFRYRCRDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFEDNPRDLQLLRHDLPLHPAVVKPHLGNVPDYLVPAALRGLVHPRKKRRKMPFSRKAKKVKTQNPLRDFKHRGKKPKPTAKPS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0051130 (positive regulation of cellular component organization), GO:0031344 (regulation of cell projection organization), GO:0031346 (positive regulation of cell projection organization), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0010976 (positive regulation of neuron projection development), GO:0010975 (regulation of neuron projection development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Bromodomain containing 1 (Predicted) (A6K7H2)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR019542: Enhancer of polycomb-like, N-terminal (domain) [47-196]
- IPR019786: Zinc finger, PHD-type, conserved site (conserved_site) [217-261]
- IPR034732: Extended PHD (ePHD) domain (domain) [268-389]
- IPR050701: Histone Modification Regulator (family) [9-1023]
- IPR001487: Bromodomain (domain) [560-668]
- IPR019787: Zinc finger, PHD-finger (domain) [214-264]
- IPR001965: Zinc finger, PHD-type (domain) [216-389]
- IPR036427: Bromodomain-like superfamily (homologous_superfamily) [554-688]
- IPR042009: BRPF2, PHD domain (domain) [214-267]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [200-390]
- IPR000313: PWWP domain (domain) [927-1037]
- IPR018359: Bromodomain, conserved site (conserved_site) [584-641]
- IPR042004: BRPF2, ePHD domain (domain) [271-388]
- IPR011011: Zinc finger, FYVE/PHD-type (homologous_superfamily) [206-279]
Sequence:
MRRKGRCHRGSAARHPSSPCSIKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEIILEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEVLPSTHGTPASASALPEPKVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIINEKRKGDCVSAVSQNMFEFLMDRFEKESYCENQKQGEHQSLIDEDAVCCICMDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPEVGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGLYMKMEPVKELTGGSTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTVRSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYWLLKRLSRNGAPLLRRLQSSLQSQRNTQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIELLRKREKLKREQVKVEQMAMELRLTPLTVLLRSVLEQLQEKDPAKIFAQPVSLKEVPDYLDHIKHPMDFATMRKRLEAQGYKNLHAFEEDFNLIVDNCMKYNAKDTVFYRAAVRLRDQGGVVLRQARREVDSIGLEEASGMHLPERPIAAPRRPFSWEEVDRLLDPANRAHMSLEEQLRELLDKLDLTCSMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQTPSIGAGTGGFEDDAAPLAPDTGEEVLPRLETLLQPRKRSRSTCGDSEVEEESPGKRLDTGLTNGFGGTRSEQEPGSGPGRKAAPRRRCASESSICSSNSPLCDSSFSTPKCGRGKPALVRRHTLEDRSELISCIENGNYAKAARIAAEVGQNSMWISTDAAASVLEPLKVVWAKCSGYPSYPALIIDPKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSEEKLFLVLFFDNKRSWQWLPKSKMVPLGVDETIDKLKMMEGRNSSIRKAVRIAFDRAMNHLSRVHGEPASDLSDID
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042393 (histone binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0006950 (response to stress), GO:0009628 (response to abiotic stimulus), GO:0051602 (response to electrical stimulus), GO:0035902 (response to immobilization stress)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043204 (perikaryon), GO:0036477 (somatodendritic compartment), GO:0042995 (cell projection), GO:0044297 (cell body), GO:0097447 (dendritic tree), GO:0043025 (neuronal cell body), GO:0120025 (plasma membrane bounded cell projection), GO:0030425 (dendrite), GO:0043005 (neuron projection)
Protein: Interleukin 12 receptor, beta 2 (A6KF50)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR003961: Fibronectin type III (domain) [137-495]
- IPR010457: Immunoglobulin C2-set-like, ligand-binding (domain) [28-121]
- IPR052672: Type I Cytokine Receptor Family, Type 2 Subfamily (family) [358-565]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [133-495]
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [137-491]
Sequence:
MAHTVRGCSLALIFLFMWLLIKANIDVCKLGTVTVQPAPVIPLGSTANISCSLNPKQGCSHYPSYNELILLKFVNDVLVEKLHGKKVHGHPSHSSIFQVTNLSLGMTLFVCKLNCSNSQKTQPVPVCGVEISVGVAPESPQSISCVQKGEHGTVACSWNSGKVTYLKTYYTLQLTGPNNVTYQNQCYSDNRQNCSRLDLGINLTPDLAESRFIVHVTATNDLGNSSSLLHTFTFLDIVRPLPPWDIRINFLNASGSRCTLQWEDEGQVVLNRLRYQPLNSTSWNMVNATNAKGRYDLQDLRPFTEYEFQISSKLHLSQGSWSNWSESLRTRTPEEEPVGTLDIWYMKQDIDCDRQQISLFWKKIKPYICYEIRVHALSEDQGGCSSIRGDSSHKVPLSGPHITAITEKKESLFISWTHIPFLEQRGCILHYRIYWKERHSTAQPELCEIQYRHSQNSHPISSLQPKVTYVLWMTAVTAAGESPQGNEREFCPQGKANWKTFVISSICIAIIVVGTFSIRYFRQKAFTLLSTLKPQWYCRTIPDPANSTWVKKYPIMEEKIQPPMDNLLMAWSAPEEPEPLIINEVLYQMIPVGRQPYCFKRGQGFQGYSTSKEDTIYLATNPQTTGTLTAESRQLVNLYKVLGSRDPDSKLGNLTSPLTVTPVNYLPTHEGYLPSNIEDLSSHEVDPSDSLDLDHQHISLSIFASSSLRPLTFCGERLTLDRLKMGYEK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0140375 (immune receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0004896 (cytokine receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0042127 (regulation of cell population proliferation), GO:0008284 (positive regulation of cell population proliferation), GO:0070665 (positive regulation of leukocyte proliferation), GO:0070663 (regulation of leukocyte proliferation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)