Protein: Obscurin isoform X2 (A0A8M6Z870)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR001849: Pleckstrin homology domain (domain) [4894-5005]
- IPR000719: Protein kinase domain (domain) [5396-6660]
- IPR000048: IQ motif, EF-hand binding site (binding_site) [4327-4349]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [5384-6668]
- IPR003961: Fibronectin type III (domain) [6279-6373]
- IPR013098: Immunoglobulin I-set (domain) [95-5371]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [5511-6528]
- IPR003598: Immunoglobulin subtype 2 (domain) [374-5361]
- IPR035899: Dbl homology (DH) domain superfamily (homologous_superfamily) [4688-4877]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [11-5372]
- IPR052385: Obscurin and Obscurin-like Regulators (family) [1247-1884]
- IPR013106: Immunoglobulin V-set domain (domain) [378-5088]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [2-6369]
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [6277-6365]
- IPR003599: Immunoglobulin domain subtype (domain) [11-5372]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [4881-5010]
- IPR000219: Dbl homology domain (domain) [4694-4876]
- IPR001452: SH3 domain (domain) [4597-4664]
- IPR007110: Immunoglobulin-like domain (domain) [182-5370]
- IPR017441: Protein kinase, ATP binding site (binding_site) [5402-5425]
Sequence:
MALRIQLVKGLEDATLCEKEACTFEVVLSHAYVRGQWTRDGVPIKSRPVCRIAMQGKNHTLTLTRVTLADMGIISFKAEGIETSAMLTVTARDIKIVKALQNVSVTERESLTFICEVNWEDVDGKWYKDNSRLKAGDNIKIRCEGKIHSLTYKSVRSEDAGEIRFTAERVSSTAMLRVKELPVHFVRPLRVKIAMYKHRALLECQVSRANAVVEWFKRNQEIVPNRKYQVVSEGVYRQLIIEDVGSSDEDTFICDAVDERTSCQLFVEEQAISILRGLSSVEVMEPKEACFKVETSIKLERAPKWTLNGQILFPCPDIRIERQGTSHRLIFTQTDSSMCGTVQFTSGKSKSEAQLTVTERPLIVKQPISDVEEKENGSVTLSCEFCPSPRVVRWFKGRTPLFASNKYTIKREKNRVEMTILGVKAADSGEYRCVAGGSETRGKVNVKVKKLKIIRHLEQVEAEEDGTAVFCCELNHESPSVQWLLNDKVLHTNHINKIQNSGKVYSLILKRLTPQESRITFKSLDISESAFLRVREKPAVFFRSLEDVAGEERGEILLQCEVSKPSVTPVWRKDGEILNSTEKYEILHVGKSLTLKIHKLIKEDGGEYSCDIGCSQTKAKVTVRDLHITIVKRIRTATVLEGESCSFECVLSHEIIDEAFWNMNGQLIVSNRRIIVANEGRKYTMSIEEVMTSDAGEVVFSIKELSCRTMLFVKEKPVRVFRDMLNVKATPGEDPELSCEITKPDATVKWLKNGRQIRVSPKYEITQKDYLVKLIIHNAAIMDSGEYCCEADGIATRARLDVRDLQHAFAKELKDVFAEEKGIVVLECETRQPATTVTWLKGLMVLRSGHKYIMKKKDVLLTLTIFNLEKSDSAVYICDVGTMQSRALLTVQGQKVVIVDELEDKECLEGETIIFRCRICPSDYTDVKWYLDETLLYTNDLNEIMMIPGGYHTLTFKQLARKDTGTIIFEAGDKRSYASLLVRERRPTITKALENTEAIEGGSLMLLCKTSKPCHIVWYKDGCLIWNSSKYLVSRSGNEARLAIRDIKDSDAGIYECNAGSVSTKATVTVKAIPAEFTKELLNQEVKEGESVTLMCEYSIPGIQFVWRKGPETLKSSEKYHMRQRKSCISLAIHNVKPDDSGNYTCICRDQKTMATVTVNAVPISFIKELKNQETEEGKTMTLRCELSKAGVPVEWLKGKQTLCPGEKYQMRHIVTILELVIRNPVPEDSGTYICVCEDQSTKADIKIRTQPITFKQKLRNQMTEEGSSVILHCEISKADIPVEWRKGNILLKSGEKYKIRQRGCILELKIFNLTQEDSGLYSCASETAETSANVTVSAQHVIFKEKLKNVVADEGKTITLHCEVSKTGVPVQWWKGDELLQFGEKYKMRERDTSVELIISEAVAEDSGVYRCVCGDQKTKATIKIVGAPATFKQDLKNQEALEGGSITLHCELSKSDAPVEWRKGDKLILPGPRFQMRLNGKTAELVISNVFPEDAGTYSCVTGDQKTTAEVKVKSLPITFKRELQNQVSIEGGSAVFTCELSKPGAPVEWRKGRVILKAGAKYHTTLEGRLTKLAINNLVEGDAGNYTCKTKDSQSTAELTVQGLPATFKATLKSQEVQEGNSVTLNCELSKAGGRVEWWKGEEMLKTGEKYQLRHKEAKAELLIRKAQSEDSGVYRCVCGEQKTEAIIKVNALPITFKQELKNQEGDEGNNVILRCELSKASADVEWMKGEEVLTPGEKYQMRQIGTKLELVIRKAIPEDSGLYICVCPDQTSKATVKINATPITFKQNLRNQEVTEGNTVALRCELSKPGATVKWWKGAEMLLAGERYQMRIEGRIAELLIKNVNSEDVGSYSCTMGKEKTVAEVKVRALPVTFKRELQNEVTKEGGQAVFSCELSKPGAQVDWRKGRVILKADDKYEMKQEGTFTQLFIHNVEPSDAGNYSCKTKDSESTAELTVKVPPITFKVKLKNQEVEEENKLTLHCELSKAGCPVEWRKGEEVLRPGYKYQIRENDVARELIIMSAMPEDSGVYSCICGEQKTKATVRVIATPVTFKQNLKNQEAPEGGVVVLHCELSKAGVPVTWLKGDEEIYSGTKYKIKQEGLAAELHIKNVLPMDVGEYSCIIGDQRTTAEVNVRAAASVFFEKELESQEATEGESVLFSCLLSNDNAPVTWRKDTDQIAQGGRYTLHRKGSTQELEIRKLRLEDAGVYTCNVRGKKSSATLRVIERVRIVKGLRDLTVTAGESAHFVCELSHENILDGVWWLASNVLQENEMNQMSICGRQHHLTLTMTTPEESGVVSFVVGNEKTSARLRVNSKPKVFIEERLKDMTIFEGDSATLSCVTSDSCTPVTWKRNNVTLLPGEKYEPLKHGKRNVLLIHKVRTEDAGIYMCDTGDMQSSATLTVKERPLFFCGELQNQVAEEGETAFLSCELSQPAVAVEWKKGAVILKPSYKFEMKQDGCELQLQINDLTSQDSGAYRCCADGIETRASITVKERPLFFREELQNQETEEGETAFLCCELSKPGVPVQWKKGAMLLKNGHKYSMTQEGNEVLLQIHDLTSQDSGIYRCCAGNLETRANIVVKEKPLFFFEELHNQQAEEGETAFLCCELSKPGVEVQWKKGAIRLRPGNKYEMKQEGCKVQLQIHDLTSEDSGTYKCCSGSLATTASVVVKEHPLYFIRMLECQEAEEGETVFLCCELSKPGAAVQWKKGSVLLKPGRKYEIKQNGGELQLQINELTSHDSGVYTCCVGSLVTSASLDVKEQPLYFCEELQRQAVEEGETAVLSCELSKAGVEVQWKKGMMLLRPGHKYKMKQDGCKMQLLILELSCQDSGIYKCCAGSLETSASLDVKESPVVFQEELQYQEVEEGKMALLTCELSKPGVAVQWKKGTLSLKPGNKYKIKQDGCLKQLQICDLKSEDSGSYRCCAGSLVTAADLVVKEPPLFFSEELQNHEAEEGKTAILSCELSKPGVSVQWKKGTVLLKPSQKYDIKENGCQLQLHIHELTAQDSGSYKCCAGSLVTTASLVVKEHPLFFSKELQNYEVEDGKTAILSCELSKPGVSVQWKKGTVLLKLSKRYEIKQDGCQQQLQIHELTAQDSGTYTCCAGSLITTASLLVKEKPLFFCDVLQNQEAEEGNTVIFRCELSKPGVSVQWKKGTALLKPGQKYEIKEDGCKLQLNVHELTAQDSGTYKCCAGSLVTTASLVVKEKLLFFSEELQNQESEEGKTAILCCELSNTGVSVQWKKGMVLLKPSKKFEIKQDGRQLQLQIHELTTQDSGTYKCCAGNIVTTASLMVKEHPLFFSEELRNQEAEEGNMVILRCELSKPGVSVQWKKGTVLLKPSKKYEMKQDGRQVYLQINELTAQDSGAYKCCAGNLITSCSVTVKEPPIFFRKNLQSLEAEEGKMATLKCELSKAGVAVQWKKGTVLLKPGKKYEMKQNGCLLQLQIYDLKSEDSGSYVCCSGSIVTTASLVVKEHPLFFSVELQNQDAEEGKTVILQCKLSKPGVSVQWKKGTVLLKPSTKYEMKQDGCQLQLQIHELTTQDSGAYKCCAGSLVTYGSIKVKEQPIFFCKSLQNLEAVEGEMAILTCELSKPGVAVQWKKGTELLKLAKKYEMKQNGCELHLKICDLKCQDSGIYKCCAAGIETTASVVVKEAPPRSKAVPEAPPRSKGKNIMDEALSGQVQQKDAVEIEESDISMLKHSDVAIQDLLEKSADDQEIQRKLLVRQKERNGSSVINESDHTIYKPPTTSVPEEQRNKLLDTSDVTKISVDQNINQVSEQSEKKSPRIDPNEQSKKAPKEIPQPPPRSKGKATNPDALLQDQHNGFKTSRPNIKEPDVDKEVKKQYDVMQPNMEATKASKEVDQTLKKEKFSQSHIEAKGQPYVSEDNRQNIDVKQTVGTTLKVSEYGSDRPGFKEITSKHIETSQEPPSNLEEIKRYGKLELNLNNESKKEPTLVPITKASEVDEFARHSNEKKELMVLDKTETHEKPNTQSKKGPDIEKVQFRDERHEKSTTVREKEASIDITTQKPKEQTILSKTLTTIPVRGMQKDSQESDTNLPHTDSRYLENVKQAVDEHHGKVLKHVTEEASNIAITGQKEVIPVEETTRMPFKDVRRESQEDESDLLHIDNGEKKNVKQVIDKHDEKVAKYVKGKVPSFAAQTFKEEAIPAEKGTSRPIKDSQNDKPNLQQTSIEDQKNVKQVVDESGRVRRDSLEADSDLLFIDTTKKMNIKQVMHEHDGKESKHIKEKEPSVKSQKLKEHIIPGEKVTAVPFRKVQKASEEVELKSNVKHVVHENYTGQSNTRPEDISVEKTSKVEQDVDLEDEPEMLEAAIKIQAAFKGYKTRKDMRLIFKEVFKNQSIDLGGTAFLECVVEGKISSVRWLKDGVDLKPGKRHTITHNPDGGCRLEICNVTHKDAGIYTCEVANKFGAVSYNGNVMVVKPQKQSQTIQPAQMPGTETVTEKTVVPTVNTEEESLRLVYDLPADDTYSKIQEKRRSLISVSSISCHSDYDTAPDVETETQSRGRETGESKTEAPTTHTSEEEQMISLQTPKTTDQLKVKGGDAKSHTPSPKRMHSYKSSANTESFSESDGDDDRRETFDIYVAKTDCHPMGGNREAFVLKEGQFVEVLDSAHPVRWLVRTKPTKITPSRQGWVSPAYLEKKTREIFSLAHESETRETPDKSRKIFTKDEHSLIQSRLIKGLLDGENSFVQEMNFFVEHHLQYLETSCKVPLTILSQKEYIFRNFRDIASFHECCILPKLEMCFSDDDVAQCFVGYAADFEMYLQFITGLPQAEACISDKNTQHFFKQYANIELADLDTQVFSVGTYLQRPMERIETYKTVLKEMIRNKAKSGQNCCLLEDAFAMVSSLPWRAENLHHLSMIENYPAPLKGLGEPIRQGHFTAWEEIPEVKSSQRGHHRHVFLFKDCIVFCKPKREVGTHTEAYIFKNKMKLSDIDVKDTAEGDDRSFGLWHEHRGMVRKIILQARSILLRLSWLKDLRDLQQRNKQPAWCAPCFEQHLTDYPAKLGQTVKLVCKVTGTPKPVVKWYKDGHAVQDDEHHITSEGQFGACYLVLTGVTVAHSGQYMCYATNPAGNASTLANIMVDVPPSFTTRLQNAVLVKGQDVQFKCSTQSVPFPSIRWFKDDIQLEDSRKHLIQSDVQTGILTLTIKKADEADVGQYQCELLNEVGSAMCKAELCAPAAEAVTVSSQKQSQTVPEAQSEGWSSSFVKNLFHILFQPGYPEPATALTVEEQHDVERQESPEEPEETHFYSDTEEHQLTEPPAVQVAIEDLTIRPGQPATFCAIITGHPRPEIQWFKDDVEISSSEYTVIVQNGARCSLTLLDTQTEDCGTYTCIASNSAGQVFCHAQLNVDTGPEEIEESREVEFGKRRKLHSVYDVYEEIGRGTFGVVKKVTHKASGECFAAKFLPLRSSTRTRAFQERDLLSRLAHRRLACLLDFFSTRRTLVLVVELCSSQSLLDHLFLKGSVTEREVQLYIQQVLEGIGYIHGMNILHLDIKTDNILMVSPTREDIKICDFGFCQEVDSSRHQYSKFGTPEFIAPEIVHQEPVTAATDIWSLGVVAYLCLTCHCPFFGENDRATLMKVAEGVLYWDTPEITSRSVEAQDFLHRVLQPDPEKRPSASECLSHEWFQGYYEDEEPVEINTKNLKSFISRRKWQRSLTCLGSVLTLRPIPELLEAPLRDVAITAPRDTQQPSSTSLSSGSSSEYDEADAWDFFQQVSEEEEDDLEEDDEHTHVSKSPTILKRDEEEVLIGEDGVHSGPLVIPVTGSSMEPIGLEQRDDSPSVLLSEGDEGLTGGPPIPRRILIKSTFYCSSEQLSPMSARHMTLRDKIQAKKQERGRKPLRASLSGRLNEPLIEYVEDSPDLEANRNQRRASMHASILKSSSFDSGVSAGHPSICTQRRSRSLDVYTQRSPVSTVQGEDEHDPEINKKTDEEEEKTEEVQVRRKLCRRSAFLSKKGPVNVRKQKDEVQESDEEHQEDSKSTCEDDHQLQNLETEAAQSDDEESVDGSHISLACSLDHGSDAGSYEALPHRSHHDAFVIAGSSGKTSACSLLQDSEDEDMERVLRSLRQDLPQAPPRRRTNSSSSGLNEVRRKSSVPLRRSSSAVPVQAAIADRESKEVLQRHASAPALQDKPPSGKSSKPGFMKIFRKHSWASHSSPQLEAPEKKHADGAQPKTPLLTLRKKMRASASSITKLFTRQSSKEDVEKKKVGPIVKNASHIMQEQMTFSVPAPTSSESPQKKSKLFSLKVPIFKKSKECPVKPSRPDVIQLAGGGALVFWKPVPSKELVTYCIQYSVNGGEWRVLSENVTDSCFTAKTLPRGPGYMFRVSYHTKTGLAPFSDPSPPAFMAIPYEDSHSPLIEMESIGSKITVPGGLGTEKSYKFLSEINRGRFSVVMQCEDSRSSQMLAAKMTPYKPEQRQLVLREYQVLRRLSHPRIVQLHSAILTSTCLLLIEELCSGRELLYNLAERNLYSEAHVTDLLEQILSAVDYLHSRRIVHLDLKSDNMLVTGKNLVKIVDLGSAQPFNPGQALNIEHIREMTDNKGYIVLPKAPEILEGQGVGPETDIWAIGVLAFIMLSADSPFHADLNWERDRNIKKGKIQFSRCYPGLSEGAINFMKNTLSNKAWARPTAAECLQNPWIEGEHPSSKHADSVVCFSADKLQAYLREREAKRDHVRTKTQLPLS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0004672 (protein kinase activity), GO:0008092 (cytoskeletal protein binding), GO:0004674 (protein serine/threonine kinase activity), GO:0017022 (myosin binding), GO:0016301 (kinase activity), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0015297 (antiporter activity), GO:0062013 (positive regulation of small molecule metabolic process), GO:0032559 (adenyl ribonucleotide binding), GO:0004683 (calmodulin-dependent protein kinase activity), GO:0030554 (adenyl nucleotide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0071840 (cellular component organization or biogenesis), GO:0030029 (actin filament-based process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0032989 (cellular component morphogenesis), GO:0061061 (muscle structure development), GO:0044085 (cellular component biogenesis), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0016043 (cellular component organization), GO:0030036 (actin cytoskeleton organization), GO:0010927 (cellular component assembly involved in morphogenesis), GO:0042692 (muscle cell differentiation), GO:0055001 (muscle cell development), GO:0060537 (muscle tissue development), GO:0006996 (organelle organization), GO:0030239 (myofibril assembly), GO:0031032 (actomyosin structure organization), GO:0097435 (supramolecular fiber organization), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0007010 (cytoskeleton organization), GO:0055007 (cardiac muscle cell differentiation), GO:0051146 (striated muscle cell differentiation), GO:0014706 (striated muscle tissue development), GO:0048738 (cardiac muscle tissue development), GO:0060538 (skeletal muscle organ development), GO:0055002 (striated muscle cell development), GO:0140694 (non-membrane-bounded organelle assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0030017 (sarcomere), GO:0031674 (I band), GO:0030018 (Z disc), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043292 (contractile fiber), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0030016 (myofibril), GO:0043232 (intracellular non-membrane-bounded organelle)