lokahq/bioreason-rl huggingface dataset:
Protein: Iodothyronine deiodinase (A0A8M1P8S9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine)
Subcellular location: Endoplasmic reticulum membrane; Single-pass membrane protein. Membrane; Single-pass membrane protein
InterPro domains:
- IPR008261: Iodothyronine deiodinase, active site (active_site) [121-135]
- IPR000643: Iodothyronine deiodinase (family) [14-253]
- IPR036249: Thioredoxin-like superfamily (homologous_superfamily) [93-235]
Sequence:
MGSAVGFALRKLFVYISAVLMVCAAILRMSMLKLLSFISPGRMRKIHMKMGERTTMTQNPKFRYEDWGPAFFSLAFIKTLFFVNWCSLGLEAFEGHSAPDSALITLDRQKTSVHRFLKGNRPLVLSFGSCTUPPFLYKLDEFKQLVKDFSNVADFLIVYLAEAHATDAWAFKNNVDISVHKNLEERLAAARTLLKEDPPCPVVVDEMNNITASKYGALPERLYVIQSGKVIYQASDLGGTSLKRFEKFWKKVNKWRRMAKCFLS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050793 (regulation of developmental process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Isocitrate dehydrogenase [NADP] (A0A8M2BF40)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR004790: Isocitrate dehydrogenase NADP-dependent (family) [3-410]
- IPR019818: Isocitrate/isopropylmalate dehydrogenase, conserved site (conserved_site) [271-290]
- IPR024084: Isopropylmalate dehydrogenase-like domain (domain) [9-401]
Sequence:
MSQKIKAGSVVEMQGDEMTRVIWELIKEKLIFPYLELDLHSYDLGMENRDATDDKVTVEAAEAVRRYNVGIKCATITPDEKRVEEFKLKQMWRSPNGTIRNILGGTVFREAIICKNIPRLVPGWIKPIIIGRHAHGDQYKATDFVVPGPGTVEMTYKPKNGGETLKFVVHDFEGTGGVALGMYNTDKSIRDFAHSSFQMGLNKGWPMYLSTKNTILKKYDGRFKDIFQEIYDKEYKAKYEAMGIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGRTVEAEAAHGTVTRHYRMHQQGKETSTNPIASIFAWTRGLLHRAELDKNAELRVFAEALEVVCVETIEAGFMTKDLAICIKGMSGVTRSDYLNTFEFLDKLAENLKIKLSSQPKL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor), GO:0004448 (isocitrate dehydrogenase [NAD(P)+] activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0030097 (hemopoiesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Collagen alpha-1(XIV) chain isoform X7 (A0A8M9PMX9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
Sequence:
MQVSGSRIKLWCPLISLALIQFLAPVSAQDQFVCTTPAIADIVILVDGSWSIGRINFRLVRMFLENLVNAFDVGIDKTRIGLAQYSGDPRIEWHLNGFSTKEAVIDAVKNLPYKGGNTLTGLALTYVLENSFKPESGARDNIPKIGILITDGKSQDDVISPAQTLRSSGVELFAIGVKNADENELKAIASEPEDTHVYNVADFSIMGTIVEGLTRTVCDGVEQQDKEIKQDSVPEETVSTPLNLLISEVTAHSFRVSWTHSAGKVEKYRVVYHPTDADIPEEIVVGGLENSVVLQNLNSLTEYEIAVFAVYRSAASDALRGSEITQALPTVSDLELYDVTDSSMRARWRDAEGASGYMILYAPLSSDTPDERELKVDETVTDVELTGLIPDTEYTVTVYATFGEEASDPATVQETTMSLKPPRNLRVTEVDHSSVRLNWDSASSKVKGYQVIYVKTDGVQTNQVELGPVTNVYLKNLSPLTEYTVAVFAVYDGGQSEALSGGFSTKLVPAPFSLMTSDVTSESFQVSWSHPARDVVLYKLIWSPTAGRDEREVMLAGDTDSYVIQDLSPFTEYKVSLAAIYKDETESSPVVVLEYTLGWTTEFPTTIPTTTPIFHQGVTNLWIDEETPFSIQVNWEVQDSDVDQYKVTYVSTDRTEETVLVSGNRRNVVLQPLLSDTKYKITVTPVYADEESSQLSMSSFGTTLPLSGPSNLRVSDEWYNRFRISWDSPQFPTMGYRVIYQPISVSGRALETFVGDDVNTLLILNLLSDTEYSVQVIASYTTGSSQPLTAKGKTLFLGVRNLNTYQVLSSSVCAQWQPHRHASVYRVVIESLHNGQKQEVRVGGGASRECFFRLSPNTQYKISVYTVLQDTEGPAVTTMVTTALAPTQPPTAAPTTSPPPTIPPAKEVCKAAKADLTFLVDGSWSIGDDNFQKIIRFLYSTTGALDVIGPEGTQVAIAQFSDDARTEFKLNSYSDKEALLDAVQRISYKGGNTKTGRAIKHVKEAIFSEDAGVRRGIPKVLVVLTDGRSQDDVNKISKEMQMEGYIIFAIGFADADYGELVNIASKPSERHVFFVDDLDAFKKIEEQLITFVCEAATATCPSVLMSGNTLAGFRMMEMFGLAEKHYSSVQGVSMEPGTFNSFPCYRLHKDALVSQPTRYLHPEGLPSDYTISMLFRILPETPQEPFALWEILDKNNEPLVGIILDNGGKTLTFFNSDYKGEFQTVTFEGPEIKKIFYGSFHKLHVAISKTAAKVVIDCKTVGEKSINAAGNISIDGVEVLGRMVRSRGRKDNSAPFQLQMFDIVCSTSWASRDKCCELPGLRVEEDCPAMPHACTCAQDSKGPPGPSGPPGGPGIRGSRGDRGEPGLTETAGHSHFVSAARLVGSQGLPGEIGPPGPQGPPGPQGPNGLSIQGPPGAPGEKGDKGEIGLPGPQGVPGANGGPGRDGPPGQRGLPGKDGPQGRQGPPGPMGSPGAPGAPGSNGPPGQLGDQGPPGPAGTKGERGERGDMQSHAAVRAIARQVCEQLIQSHLSRYNSILNQIPSQSVSVRTVPGPPGEPGRPGLQGPQGEQGPPGRPGFPGASGQNGRPGERGLPGERGEKGSPGVGTQGPRGPPGSPGPAGEGRTGSQGPPGRPGIQGTQGRPGTPGSPGPAGPPGYCDQNSCLGYNVGVQQLSSNPYQNYGPATNYNPEDEEEDDPYGGYRAYPPQYYQPSYPDPRGARPGPVHPGDTAGMRAPGARRFTRSTAEEGIVHQPQEHVKEEELW
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0045229 (external encapsulating structure organization), GO:0043062 (extracellular structure organization), GO:0022607 (cellular component assembly), GO:0030198 (extracellular matrix organization), GO:0085029 (extracellular matrix assembly), GO:0071711 (basement membrane organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062023 (collagen-containing extracellular matrix)
Protein: Hepatitis A virus cellular receptor 1 homolog isoform X2 (A0A8M3B4U0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR013106: Immunoglobulin V-set domain (domain) [31-130]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [26-137]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [28-118]
- IPR007110: Immunoglobulin-like domain (domain) [31-113]
- IPR003599: Immunoglobulin domain subtype (domain) [24-131]
Sequence:
MTDLHSWFLSSWILCCLTICRCSDIIVQSFEGDNVTLPCKYDSRYHGKCEICWMRGDIPSRGCGEEIIASDGDKVSTRNSDRYDLAGPIQHGDVSLTIFNIDKTDSGKYGCRVHVPGWFNDEKYYVHLIVDDAIIPTTLETTSMSSSTSEHETTGVYTTAMTEAPATTPPDPLVTTISGLLTPESQTTETSGDNKTRKEISSTISPSYAPRSSTAGMWLSNTTSEPSVSVVYHESSSAESKDNVTVSAVLVPVLLLLLALIAIAAAFMWKQKKKTRASLEVRQNSEISVIYSNSGSSVGLYNREMAVENVYQIQAESEYEQWH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0008289 (lipid binding), GO:0097367 (carbohydrate derivative binding), GO:0070891 (lipoteichoic acid binding), GO:0001530 (lipopolysaccharide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006810 (transport), GO:0016192 (vesicle-mediated transport), GO:0006996 (organelle organization), GO:0061024 (membrane organization), GO:0007010 (cytoskeleton organization), GO:0006909 (phagocytosis), GO:0006897 (endocytosis), GO:0010324 (membrane invagination), GO:0099024 (plasma membrane invagination), GO:0043277 (apoptotic cell clearance), GO:0006911 (phagocytosis, engulfment), GO:0043652 (engulfment of apoptotic cell)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009986 (cell surface)
Protein: Stress-activated protein kinase JNK (A0A8M6YV43)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Responds to activation by environmental stress and pro- inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity
Subcellular location: Cytoplasm
InterPro domains:
- IPR003527: Mitogen-activated protein (MAP) kinase, conserved site (conserved_site) [102-204]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [188-200]
- IPR000719: Protein kinase domain (domain) [67-362]
- IPR050117: Mitogen-activated protein (MAP) kinase (family) [65-387]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [55-398]
- IPR008351: Mitogen-activated protein (MAP) kinase, JNK (family) [117-376]
Sequence:
MVFMNRRFLYNCSAPVLDVKIAFCQGFGKQVDVSYIAQHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAGYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPSPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDCLFPADSEHNKLKASQARDLLSKMLIIDPAKRISVDEALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHSIDEWKELIYKEVMNFEERTKNGVVKGQPSPSGAAVNSSESLPPSSSVNDISSMSTDQTLASDTDSSLETSAGPLGCCR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity), GO:0004707 (MAP kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048732 (gland development), GO:0048483 (autonomic nervous system development), GO:0007399 (nervous system development), GO:0061008 (hepaticobiliary system development), GO:0048484 (enteric nervous system development), GO:0001889 (liver development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Gonadotropin releasing hormone receptor 1 isoform X1 (A0A8M9P1N9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein
InterPro domains:
- IPR017452: GPCR, rhodopsin-like, 7TM (domain) [55-321]
- IPR000276: G protein-coupled receptor, rhodopsin-like (family) [40-329]
- IPR001658: Gonadotrophin-releasing hormone receptor family (family) [37-307]
Sequence:
MSGNVSLSLISLLENSSLASSSSPQSPQWETPTFTTAARYRVVATLVLFVFAAVSNLSVLISVTRGRGRHLASHLRPLIASLASADLVMTFVVMPLDAIWNITVQWYAGDAMCKLLCFLKLFAMHSAAFILVVVSLDRHHAILHPLEALDAGRRNRRMLLAAWILSVLLASPQLFIFRAIKAEGVDFVQCATHGSFQHRWQETAYNMFHFVTLYVFPLLVMSFCYTRILVEINRQMPRGKGKGGEPCLRRSGADMIPKARMKTLKMTIIIVASFVVCWTPYYLLGIWYWFQPRMLQVTPEYVHHALFVFGNLNTCCDPVIYGFFTPSFRADITSCFSRRNQNCSPKSLDRLSARRGGASGEAESDLGSGDQPSGQTA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0016500 (protein-hormone receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0004930 (G protein-coupled receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007186 (G protein-coupled receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure), GO:0009986 (cell surface)
Protein: Voltage-dependent anion-selective channel protein 3 (A0A8M2BEA1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR027246: Eukaryotic porin/Tom40 (family) [29-301]
- IPR001925: Porin, eukaryotic type (family) [28-307]
- IPR023614: Porin domain superfamily (homologous_superfamily) [15-308]
Sequence:
MSEKGHKQKGSSETCHHCKPKTCANMAVPPAYADLGKSAKDIFSKGYGFGTVKLDLKTKSQSGVEFTTGGSSNTDTGKAAGNLETKYKVKELGLSLNQKWNTDNVLTTEVTLEDQLTKGLKLGLDTSFVPNTGKKSAKLKTGYKREYMNVGCDLDFDLAGPTVHAAAVLGYEGWLAGYQMAFDTAKSKLAQNNFALGYKAGDFQLHTNVNDGTEFGGSIYQKVNGQLETAVNLAWTAGSNNTRFGIAAKYQLDKDSSVSAKVNNASLVGVGYTQSLRPGVKLTLSALIDAKNFNAGGHKVGMGFELEV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0008509 (monoatomic anion transmembrane transporter activity), GO:0015267 (channel activity), GO:0022839 (monoatomic ion gated channel activity), GO:0005253 (monoatomic anion channel activity), GO:0022836 (gated channel activity), GO:0005244 (voltage-gated monoatomic ion channel activity), GO:0008308 (voltage-gated monoatomic anion channel activity), GO:0022832 (voltage-gated channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0040007 (growth), GO:0048589 (developmental growth), GO:0048856 (anatomical structure development), GO:0031099 (regeneration), GO:0042246 (tissue regeneration), GO:0031101 (fin regeneration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Bifunctional epoxide hydrolase 2 isoform X1 (A0A8M9P8W1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR023198: Phosphoglycolate phosphatase-like, domain 2 (homologous_superfamily) [17-95]
- IPR023214: HAD superfamily (homologous_superfamily) [10-212]
- IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [227-522]
- IPR000639: Epoxide hydrolase-like (family) [249-509]
- IPR000073: Alpha/beta hydrolase fold-1 (domain) [242-499]
- IPR036412: HAD-like superfamily (homologous_superfamily) [1-211]
Sequence:
MKKAVLFSLWGGVVTPQIGQAFQKFEETTGISKGFIKNVETKLGSDNALHRAEKGKTTLAQMIPEFDAECQKVAADQGLSLPAQFSTQKLFDDMGKVEFNMAFLDAAAVLRRNGIATGILANIWVDDTAQRGSIARVLSVLESRFDLVLRSCHAGVRIPEPDFFKHALEKLAVKPQEALWLDVDEESVKAAEGLGIMAVQVKDVTEALTEIQKLTGIEVTSDLQPPSCDPEKVSHGYVNIKIPALADAGFRVLAPDMKGYGGSTAPPDIEEYSQEQIMLDLVTFLDKMAIAQVTLVGHDWGGVLVWNMAQFHPERVRAVASLNTPLFPVDPNTNPIEKLMAIPIFDYQIYFQKPGVAEAELEKNLERTFKLMFISSSDTDGFPKLSPAGVCQRGGLFVGSPDDPPRSSMLSVSALQFYTEQYSKSGFRGPLNWYRNYERNWRWMVSRPRAKILMPALMVTAGKDPVLLPAFATGMENLIPNLSRGHIEECGHWTQMERPAELNKILISWLKETHQKASISVHPKL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016801 (hydrolase activity, acting on ether bonds), GO:0016803 (ether hydrolase activity), GO:0004301 (epoxide hydrolase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0001568 (blood vessel development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0030097 (hemopoiesis), GO:0060841 (venous blood vessel development), GO:0002244 (hematopoietic progenitor cell differentiation), GO:0001944 (vasculature development), GO:0072359 (circulatory system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Grainyhead-like protein 3 homolog isoform X4 (A0A8M9Q2K1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
- IPR057520: GRHL1/CP2, C-terminal domain (domain) [467-556]
- IPR007604: CP2 transcription factor (domain) [175-417]
- IPR040167: Transcription factor CP2-like (family) [48-555]
Sequence:
MTKEIEALMVQQNESFSHIRTYESYVMDYWTNMDSGNLSKTKPRLASDEDLATLNLLYDACKPSKEQKMTSCARESSMYKSMERTANSSSPELAPLENAHIMKFLSENMSFNPSKPSTDSYTTDNYDKQVNLNNIFDSLLPQPSQKSWQPDQTFLEATPEHIGHNGFGGQTSPVYSDSYSSPGRYRNDFQFLLGAPQASQHKTTEIPMVYLNKGQFYPITLQGVDSTAGVPCSKVKTVIMAVFENDKSPEMQLKYWNHWHARQPTVKQRVIDIADYKEVFSGVSNVEEVAFNALSFIWNTNEEAKVHIGINSLSTDFSSQKGVKGLPLNLQIDTYDFSSGNNRLIHRAVCQVKIFCDKGAERKMRDEERKRSKRRTKNTADSSNNNCKQALVSSSVGKDSTYFKTLDDHVTQPVLFIPEMHFSTMQRCGLVPPVSLEESDRSSLKRYADANEQSSSPPCKQPRRDEQRVLLYVRRESEEVFDALMLNTPNLKGLKEAISEKYGMQEDTIGKIFKKCKRGIFVNMDDNIIEHYSNHSAFLIEISEVIVNHYQVTLMEL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0008219 (cell death), GO:0007389 (pattern specification process), GO:0035295 (tube development), GO:1902742 (apoptotic process involved in development), GO:0012501 (programmed cell death), GO:0048598 (embryonic morphogenesis), GO:0009888 (tissue development), GO:0003002 (regionalization), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0030917 (midbrain-hindbrain boundary development), GO:0009790 (embryo development), GO:0060561 (apoptotic process involved in morphogenesis), GO:0048839 (inner ear development), GO:0007420 (brain development), GO:0007399 (nervous system development), GO:0021915 (neural tube development), GO:0007423 (sensory organ development), GO:0006915 (apoptotic process), GO:0007417 (central nervous system development), GO:0021532 (neural tube patterning), GO:0060429 (epithelium development), GO:0009952 (anterior/posterior pattern specification), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development), GO:0043583 (ear development), GO:0021903 (rostrocaudal neural tube patterning)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Catenin delta-2 isoform X5 (A0A8M3B0B1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR000225: Armadillo (repeat) [559-1000]
- IPR028435: Plakophilin/Delta catenin (family) [48-1040]
- IPR011989: Armadillo-like helical (homologous_superfamily) [529-1019]
- IPR016024: Armadillo-type fold (homologous_superfamily) [529-1005]
Sequence:
MPVPDQPSGTENSSMLSPVLNASNGDGSETETTSAILASVKEQELQFERLTRELEAERQIVATQLERCKLGSETGSMSSISSADEKFRWNNQDGQKDIEEELTTGLELVDSCIRSLQESGILDSQEFTAGERPGILSQSALQLNNQEGTFPYPVSYHSNQTLALGDLSASQPPRSGQVGGALHSYNQVTSNRVAQLAARETAARAHSRDSYAQSHGSAFHMPDDQPTVPVNYSCATLPAQRVSSPFSMQALGSPSKLQRLGSASDMPSYATLARVSSPKQSPSRLAKSYSTSSPINMAAGGGSSSSPLHMAGAGNVSNSSPLHQLSAAVGSYATLSPTKRMLHTTDQYKISHDLYANATLQRPGSLAGSRGSYSSQHSHLGSELRPLQSPEHHIDPIYEDRVYQKAPLRNFNQAQDPMNQFCDQVLNFLLCPYSPVIAPSSPGVDSIPLQRTGSQNATGTFPRAGYATGPGASTADYANPYRTLQFCPSTDSPYSKSGPALPPEATLVRSPSVDSIQKDPREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKSEIRRQGGIQLLVDLLDHRMTDVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDVEIRELLTGVLWNLSSCDALKMPIIQDALAVLTNTVIIPHSGWDTSPLQDDRKLHLHSSQVLRNATGCLRNVSSAGEEARRRMRECEGLTDALLYVIQTALGTSEIDSKTIENCVCILRNLSYRLAAETSQGQQMGSEELDGVLCTDASGKDAESSGCWGKKKKKKKSHDQWDGVGPFPDSSDPPKGLQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVYIRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNNNSTGTGGSSKSMSDDTITAICCALHEVITKNMENTKALRDAGGIEKLIGIARSKGDKHTPKVVKAASQVLNSMWQYRDLRSLYKKDGYSQYHFVGSSSTIERDRQRPYSSSRTPSISPVRTSPNNRSASAPTSPREMMSLKERKTDYESTGSNSTYHGNKGEHTSRKDAMAAQISSGTSTLFRGAYMSPADDIKHNQVSAQGNPPEAYPPFQTPPGANFEEPYYEDQAHKRPPPAADGTMHLGLKSTGNYVDFYSASRPYSELNYETSHYPASPDSWV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048870 (cell motility), GO:0030154 (cell differentiation), GO:0016477 (cell migration), GO:0048731 (system development), GO:0001764 (neuron migration), GO:0022008 (neurogenesis), GO:0007399 (nervous system development), GO:0048699 (generation of neurons)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction), GO:0070161 (anchoring junction), GO:0005911 (cell-cell junction), GO:0043296 (apical junction complex), GO:0005912 (adherens junction), GO:0005915 (zonula adherens)
Protein: Gamma-adducin isoform X2 (A0A8M6YXA3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane; Peripheral membrane protein; Cytoplasmic side
InterPro domains:
- IPR001303: Class II aldolase/adducin N-terminal (domain) [139-321]
- IPR036409: Class II aldolase/adducin N-terminal domain superfamily (homologous_superfamily) [126-382]
- IPR051017: Aldolase class II Adducin subfamily (family) [20-674]
Sequence:
MSGEPRQEVVTTPPPPSVGKREGYFDRVNENDPEYLRARNMSPDLRQDFNMMEQKKRVTQILQSPAFKDELEGMIQEQMNKGNNPTGLLALRQIADFFMSSSVAGFSTSPLSLGMVTPINDMFSVESSTMVKGEKQTRCKLASLYRIVDLFSWAHFASCYITVRVSKEQDHILIIPRGLSFAEASASNLVKVNILGDVIDQGSTNLRIDAAGFSPHAAIYSIRPDVRCIVHISTPATAAVSSMKCGLLPISQEALILGDIAYYNYQGSLDEQEERVELQKALGPTAKVLVLRNHGIVALGETIEEAFHYIYGAQYACEIQVNAFSCAGGMENLIVLDLEKFKARTQGVAQVGVNMGSQQKWRLGELEFESLMRMLDNLGYRTGYTYRHPIVREKPRHKSEVEIPATVTAFMFDEDDAPRFPLKLLQQRQQREKTRWLNSPNCYMKVNVADGASEENRRTKTTWMKSDDGGNASGTPIRIEDPNQFVPLNTNPSEVLQKRNKIREQNRFDVMTAGPQSQKLAGIVVERPPGQSPVQPYMGNDEEETGALPPNPFSELNEKEEHQRRLRIDDEEQLTSDDASTLSQSVSPQHTPAKEENHTGVMLNGKDDHGDEDELIKRVSQLTTSLESMEISVRSGEKIEEALTPESSPSKSPNKKKKKFRTPSFLKKNKKKEKVEA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0005200 (structural constituent of cytoskeleton)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0032502 (developmental process), GO:0007275 (multicellular organism development), GO:0048856 (anatomical structure development), GO:0048731 (system development), GO:0061008 (hepaticobiliary system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton)