lokahq/bioreason-rl huggingface dataset:
Protein: D-amino acid oxidase (A0A077JN67)
Organism: Rubrobacter xylanophilus
InterPro domains:
- IPR023209: D-amino-acid oxidase (family) [6-322]
- IPR006076: FAD dependent oxidoreductase (domain) [7-315]
Sequence:
MRDCGRAVVVGCGVIGLSAALVLRERGFGVRVVAREPPERTTSAVAAAVWYPYRAYPEDRVLRWGARTYEVFRGLAADPRSGVRLREGVELLRRTSTGEPWWRGAVSGFRRCRREELPPGCRGGYRFVAPVAEMPAYLAYLLGRFREAGGELELREVSSLEEVAGGADVAVNCSGAGARKLVGDPAVFPIRGQVLRVANPGLERFMLDEENPEGLTYIVPRTEDCVLGGTAEEGSWSTRPDPVTAYSILHRCTALEPRLQGAPVLEHRAGLRPGRPEVRLERTTLPDGTPCIHNYGHGGSGVTLSWGCAEEAAELAAAALDRNP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016638 (oxidoreductase activity, acting on the CH-NH2 group of donors), GO:0016641 (oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor), GO:0008131 (primary amine oxidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006520 (amino acid metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044282 (small molecule catabolic process), GO:1901575 (organic substance catabolic process), GO:0006082 (organic acid metabolic process), GO:0044248 (cellular catabolic process), GO:0016054 (organic acid catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0043436 (oxoacid metabolic process), GO:1901605 (alpha-amino acid metabolic process), GO:0009063 (amino acid catabolic process), GO:0009068 (aspartate family amino acid catabolic process), GO:0019752 (carboxylic acid metabolic process), GO:1901606 (alpha-amino acid catabolic process), GO:0046395 (carboxylic acid catabolic process), GO:0009066 (aspartate family amino acid metabolic process), GO:0043649 (dicarboxylic acid catabolic process), GO:0006531 (aspartate metabolic process), GO:0043648 (dicarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Zinc metalloprotease (A5JIY6)
Organism: Pseudomonas aeruginosa
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
- IPR004387: Peptidase M50, putative membrane-associated zinc metallopeptidase (family) [2-450]
- IPR008915: Peptidase M50 (domain) [10-436]
- IPR041489: PDZ domain 6 (domain) [129-278]
- IPR036034: PDZ superfamily (homologous_superfamily) [87-306]
- IPR001478: PDZ domain (domain) [114-280]
Sequence:
MSALYMIVGTLVALGVLVTFHEFGHFWVARRCGVKVLRFSVGFGTPLVRWHDRHGTEFVVAAIPLGGYVKMLDEREAEVPAHLLEQSFNRKTVRQRIAIVAAGPIANFLLAILFFWVVALLGSQQVRPVIGSVAPESLAAQAGLEAGQELLAVDGEPVTGWNGVNLQLVRRLGESGTLEVRVQEKGSNVDSTHQVRLDGWLKGEDNPDPIASLGIRPWRPALPPVLAELDPKGPAQAAGLKLGDRLQSIDGIAVDDWQQVVDSVRARPGQRVQLKVLRDGEVLDVALELAVRGEGKARSGYMGAGVAGTEWPAEMLREVSYGPLEAVGQALSRTWTMSLLTLDSIKKMLLGELSVKNLSGPITIAKVAGASAQSGVGDFLNFLAYLSISLGVLNLLPIPVLDGGHLLFYLVEWVRGRPLSERVQAWGMQIGISLVVGVMLLALVNDLSRL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0004175 (endopeptidase activity), GO:0008237 (metallopeptidase activity), GO:0004222 (metalloendopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0042597 (periplasmic space)
Protein: Nuclease SbcCD subunit D (Q9X1X0)
Organism: Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826
Function: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
InterPro domains:
- IPR029052: Metallo-dependent phosphatase-like (homologous_superfamily) [5-300]
- IPR004593: Nuclease SbcCD subunit D (family) [7-248]
- IPR050535: DNA Repair and Maintenance Complex Component (family) [6-384]
- IPR004843: Calcineurin-like, phosphoesterase domain (domain) [7-219]
- IPR054045: Mre11, C-terminal domain (domain) [339-385]
- IPR041796: DNA double-strand break repair protein Mre11, N-terminal metallophosphatase domain (domain) [8-241]
- IPR054406: Mre11, accessory DNA binding capping domain (domain) [271-326]
Sequence:
MINLKELKILHTSDWHLGVTSWTSSRPVDRREELKKALDKVVEEAEKREVDLILLTGDLLHSRNNPSVVALHDLLDYLKRMMRTAPVVVLPGNHDWKGLKLFGNFVTSISSDITFVMSFEPVDVEAKRGQKVRILPFPYPDESEALRKNEGDFRFFLESRLNKLYEEALKKEDFAIFMGHFTVEGLAGYAGIEQGREIIINRALIPSVVDYAALGHIHSFREIQKQPLTIYPGSLIRIDFGEEADEKGAVFVELKRGEPPRYERIDASPLPLKTLYYKKIDTSALKSIRDFCRNFPGYVRVVYEEDSGILPDLMGEIDNLVKIERKSRREIEEVLRESPEEFKEELDKLDYFELFKEYLKKREENHEKLLKILDELLDEVKKSEA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0033554 (cellular response to stress), GO:0006259 (DNA metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0006974 (cellular response to DNA damage stimulus), GO:0006281 (DNA repair)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0140513 (nuclear protein-containing complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: D-amino acid oxidase (A5U3S4)
Organism: Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
InterPro domains:
- IPR023209: D-amino-acid oxidase (family) [4-317]
- IPR006076: FAD dependent oxidoreductase (domain) [8-315]
Sequence:
MAIGEQQVIVIGAGVSGLTSAICLAEAGWPVRVWAAALPQQTTSAVAGAVWGPRPKEPVAKVRGWIEQSLHVFRDLAKDPATGVRMTPALSVGDRIETGAMPPGLELIPDVRPADPADVPGGFRAGFHATLPMIDMPQYLDCLTQRLAATGCEIETRPLRSLAEAAEAAPIVINCAGLGARELAGDATVWPRFGQHVVLTNPGLEQLFIERTGGSEWICYFAHPQRVVCGGISIPGRWDPTPEPEITERILQRCRRIQPRLAEAAVIETITGLRPDRPSVRVEAEPIGRALCIHNYGHGGDGVTLSWGCAREVVNLVGGG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016638 (oxidoreductase activity, acting on the CH-NH2 group of donors), GO:0016641 (oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor), GO:0008131 (primary amine oxidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006520 (amino acid metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006082 (organic acid metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0008652 (amino acid biosynthetic process), GO:0016053 (organic acid biosynthetic process), GO:0043436 (oxoacid metabolic process), GO:1901605 (alpha-amino acid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:1901607 (alpha-amino acid biosynthetic process), GO:0009066 (aspartate family amino acid metabolic process), GO:0046394 (carboxylic acid biosynthetic process), GO:0016607 (nuclear speck), GO:0009067 (aspartate family amino acid biosynthetic process), GO:0006553 (lysine metabolic process), GO:0009085 (lysine biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Periplasmic binding protein (Q8ZPA3)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
InterPro domains:
- IPR001638: Solute-binding protein family 3/N-terminal domain of MltF (domain) [30-252]
Sequence:
MLSKKFGLSMIVLGIMSSSAFADSIVEGRTLNVAVSPASPPMLFKSADGKLQGIDLELFSSYCQSRHCKLNITEYAWDGMLGAVASGQADVAFSGISITDKRKKVIDFSEPYYINSFYLVSMANHKITLNNLNELNKYSIGYPRGMAYSDLIKNDLEPKGYYSLSKVKLYPTYNETMADLKNGNLDLAFIEEPVYFTFKNKKKMPIESRYVFKNVDQLGIAFKKGSPVRDDFNLWLKEQGPQKISGIVDSWMK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0036094 (small molecule binding), GO:0022857 (transmembrane transporter activity), GO:0043167 (ion binding), GO:0040011 (locomotion), GO:0043168 (anion binding), GO:0043177 (organic acid binding), GO:0031406 (carboxylic acid binding), GO:0016597 (amino acid binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0071705 (nitrogen compound transport), GO:0006865 (amino acid transport), GO:0015849 (organic acid transport), GO:0015711 (organic anion transport), GO:0015804 (neutral amino acid transport), GO:0046942 (carboxylic acid transport), GO:0042940 (D-amino acid transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0031975 (envelope), GO:0042597 (periplasmic space), GO:0030313 (cell envelope), GO:0030288 (outer membrane-bounded periplasmic space)
Protein: Secretion system regulator: transcriptional activator (Q7CQM5)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
InterPro domains:
- IPR058245: NreC/VraR/RcsB-like, phosphoacceptor receiver domain (domain) [6-121]
- IPR016032: Signal transduction response regulator, C-terminal effector (homologous_superfamily) [143-211]
- IPR039420: Transcriptional regulatory protein WalR-like (family) [3-210]
- IPR011006: CheY-like superfamily (homologous_superfamily) [3-130]
- IPR000792: Transcription regulator LuxR, C-terminal (domain) [143-208]
- IPR001789: Signal transduction response regulator, receiver domain (domain) [4-121]
Sequence:
MKEYKILLVDDHEIIINGIMNALLPWPHFKIVEHVKNGLEVYNACCAYEPDILILDLSLPGINGLDIIPQLHQRWPAMNILVYTAYQQEYMTIKTLAAGANGYVLKSSSQQVLLAALQTVAVNKRYIDPTLNREAILAELNADTTNHQLLTLRERQVLKLIDEGYTNHGISEKLHISIKTVETHRMNMMRKLQVHKVTELLNCARRMRLIEY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0032993 (protein-DNA complex)
Protein: histidine kinase (Q8ZPP5)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Subcellular location: Cell inner membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein
InterPro domains:
- IPR005467: Histidine kinase domain (domain) [402-614]
- IPR003594: Histidine kinase/HSP90-like ATPase domain (domain) [507-614]
- IPR004358: Signal transduction histidine kinase-related protein, C-terminal (domain) [543-611]
- IPR036641: HPT domain superfamily (homologous_superfamily) [788-908]
- IPR036890: Histidine kinase/HSP90-like ATPase superfamily (homologous_superfamily) [449-616]
- IPR011006: CheY-like superfamily (homologous_superfamily) [689-815]
- IPR003660: HAMP domain (domain) [314-369]
- IPR036097: Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily (homologous_superfamily) [380-461]
- IPR001789: Signal transduction response regulator, receiver domain (domain) [689-808]
- IPR003661: Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (domain) [395-460]
Sequence:
MNLLNLKNTLQTSLVIRLTFLFLLTTIIIWLLSVLTAAYISMVQKRQHIIEDLSVLSEMNIVLSNQRFEEAERDAKNLMYQCSLATEIHHNDIFPEVSRHLSVGPSNCTPTLNGEKHRLFLQSSDIDENSFRRDSFILNHKNEISLLSTDNPSDYSTLQPLTRKSFPLYPTHAGFYWSEPEYINGKGWHASVAVADQQGVFFEVTVKLPDLITKSHLPLDDSIRVWLDQNNHLLPFSYIPQKIRTQLENVTLHDGWQQIPGFLILRTTLHGPGWSLVTLYPYGNLHNRILKIILQQIPFTLTALVLMTSAFCWLLHRSLAKPLWRFVDVINKTATAPLSTRLPAQRLDELDSIAGAFNQLLDTLQVQYDNLENKVAERTQALNEAKKRAERANKRKSIHLTVISHELRTPMNGVLGAIELLQTTPLNIEQQGLADTARNCTLSLLAIINNLLDFSRIESGHFTLHMEETALLPLLDQAMQTIQGPAQSKKLSLRTFVGQHVPLYFHTDSIRLRQILVNLLGNAVKFTETGGIRLTVKRHEEQLIFLVSDSGKGIEIQQQSQIFTAFYQADTNSQGTGIGLTIASSLAKMMGGNLTLKSVPGVGTCVSLVLPLQEYQPPQPIKGTLSAPFCLHRQLACWGIRGEPPHQQNALLNAELLYFSGKLYDLAQQLILCTPNMPVINNLLPPWQLQILLVDDADINRDIIGKMLVSLGQHVTIAASSNEALTLSQQQRFDLVLIDIRMPEIDGIECVRLWHDEPNNLDPDCMFVALSASVATEDIHRCKKNGIHHYITKPVTLATLARYISIAAEYQLLRNIELQEQDPSRCSALLATDDMVINSKIFQSLDLLLADIENAVSAGEKIDQLIHTLKGCLGQIGQTELVCYVIDIENRVKMGKIIALEELTDLRQKIRMIFKNYTIT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0060089 (molecular transducer activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0035556 (intracellular signal transduction), GO:0000160 (phosphorelay signal transduction system)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: FapC amyloid-like fimbriae protein (C4IN70)
Organism: Pseudomonas sp. UK4
InterPro domains:
Sequence:
MKPTMALKPLVFALAALMAVAAQAGPAEKWKPTPAPTGTVAAAVTDTQVSKDNKFDDTKTLNNAGANGSLSNSKGNLGANIAAGSGNQQDNAAAITSSAGDAATVFAVADIYQESKDNKFTNKGTQNNALLNNSANNSSGNVGVNVAAGQGNQQKNNLAIVTADGKNVAAASNTEQVSLDNHFLNEASSKHSYKPQYVVNNAGLLNSANNASGNIGVNVAAGAGNQQSNTLTLGSGCTVCAAGTGSKLAF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:0016043 (cellular component organization), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:1990000 (amyloid fibril formation), GO:0097435 (supramolecular fiber organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0031975 (envelope), GO:0042597 (periplasmic space), GO:0030313 (cell envelope), GO:0030288 (outer membrane-bounded periplasmic space)
Protein: CD80 antigen, isoform CRA_b (A6IR63)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Single- pass type I membrane protein
InterPro domains:
- IPR013162: CD80-like, immunoglobulin C2-set (domain) [147-231]
- IPR037676: CD80, IgC-like domain (domain) [147-237]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [40-240]
- IPR051713: T-cell Activation and Immune Regulation Protein (family) [23-239]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [43-240]
- IPR007110: Immunoglobulin-like domain (domain) [17-235]
- IPR003599: Immunoglobulin domain subtype (domain) [40-144]
Sequence:
MAYSCQLMQESPLLGFPRLRFIHLFVLLLVGLFQISSGIVGQVSKSVREKALLSCDYKFCSEEQSIHRIYWQKHDKMVLSVISGVPEVWPEYKNRTVYDIANNYSFSLLGLILSDRGTYTCVVQRYEGGSYVVKHLTTVELSVRADFPTPNITESGNPSADIKRITCFASGGFPKPRLSWLENGRELNGINTTISQDPESELYTISSQLDFNTTYDHFIDCFIEYGDAHVSQNFTWEKRRCFRRRNEASRETNKNLYIGPVEAAAEQTV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0051240 (positive regulation of multicellular organismal process), GO:0002684 (positive regulation of immune system process), GO:0050794 (regulation of cellular process), GO:0002682 (regulation of immune system process), GO:0051239 (regulation of multicellular organismal process), GO:0048522 (positive regulation of cellular process), GO:0002696 (positive regulation of leukocyte activation), GO:0042127 (regulation of cell population proliferation), GO:0030155 (regulation of cell adhesion), GO:0002694 (regulation of leukocyte activation), GO:0045785 (positive regulation of cell adhesion), GO:0050865 (regulation of cell activation), GO:0050867 (positive regulation of cell activation), GO:0008284 (positive regulation of cell population proliferation), GO:0051251 (positive regulation of lymphocyte activation), GO:0022409 (positive regulation of cell-cell adhesion), GO:0022407 (regulation of cell-cell adhesion), GO:0070665 (positive regulation of leukocyte proliferation), GO:0070663 (regulation of leukocyte proliferation), GO:0051249 (regulation of lymphocyte activation), GO:0032946 (positive regulation of mononuclear cell proliferation), GO:0050670 (regulation of lymphocyte proliferation), GO:0050870 (positive regulation of T cell activation), GO:0050863 (regulation of T cell activation), GO:0032944 (regulation of mononuclear cell proliferation), GO:1903037 (regulation of leukocyte cell-cell adhesion), GO:1903039 (positive regulation of leukocyte cell-cell adhesion), GO:0050671 (positive regulation of lymphocyte proliferation), GO:0042102 (positive regulation of T cell proliferation), GO:0042129 (regulation of T cell proliferation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009986 (cell surface)
Protein: Rho family GTPase 2, isoform CRA_a (A6HJD0)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR001806: Small GTPase (family) [1-170]
- IPR003578: Small GTPase Rho (family) [1-126]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [1-128]
Sequence:
MWDTSGSSYYDNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKVVLVGCKLDMRTDLATLRELSKQRLIPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVFHVATVASLGRGGHRQLRRTDSRRGLQRSTQLPGRPDRGNEGEIHKDRAKSCNLM
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0050793 (regulation of developmental process), GO:0051240 (positive regulation of multicellular organismal process), GO:0050794 (regulation of cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0051239 (regulation of multicellular organismal process), GO:0051094 (positive regulation of developmental process), GO:0048522 (positive regulation of cellular process), GO:0050773 (regulation of dendrite development), GO:0045597 (positive regulation of cell differentiation), GO:2000026 (regulation of multicellular organismal development), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0045595 (regulation of cell differentiation), GO:0016043 (cellular component organization), GO:0051130 (positive regulation of cellular component organization), GO:0051128 (regulation of cellular component organization), GO:0051962 (positive regulation of nervous system development), GO:0022604 (regulation of cell morphogenesis), GO:0031344 (regulation of cell projection organization), GO:0031346 (positive regulation of cell projection organization), GO:0010256 (endomembrane system organization), GO:0060284 (regulation of cell development), GO:0010720 (positive regulation of cell development), GO:0048814 (regulation of dendrite morphogenesis), GO:0050769 (positive regulation of neurogenesis), GO:0051960 (regulation of nervous system development), GO:0006996 (organelle organization), GO:0010770 (positive regulation of cell morphogenesis involved in differentiation), GO:0010769 (regulation of cell morphogenesis involved in differentiation), GO:0007030 (Golgi organization), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0050767 (regulation of neurogenesis), GO:0050775 (positive regulation of dendrite morphogenesis), GO:0010975 (regulation of neuron projection development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0005769 (early endosome), GO:0031982 (vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle)