Protein: Phosphatidylinositol 4-kinase lsb6 (Q9UT42)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: May play a role in endocytic and/or exocytic pathways
Subcellular location: Cell membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein
InterPro domains:
- IPR018936: Phosphatidylinositol 3-/4-kinase, conserved site (conserved_site) [334-354]
- IPR000403: Phosphatidylinositol 3-/4-kinase, catalytic domain (domain) [145-520]
- IPR039756: Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 (family) [60-539]
Sequence:
MESTFHSDTLDSFPNYQENSLNTNEEQTNPLESLRDGWASSNSSSSSSLLLPDENEGNEVFGSLKGLVTQSKFGQWANKLSKSLQARRRKSESISKPRVYYSVFMAPSWVLHAEKHWEEYPHYAGYDYKDYVRLLDATKEAIAHGVFPVLISKGSSGSYFVKNKVQKNIAVFKPKDEEPYGKLNPKWTKWFHRNLFPCFFGRSCLIPNTSYLSEAAACVLDRGLGLYLVPYTSVASISSPTFNYDYFARKAFLTRNKPLPEKTGSFQQFLDGFVVASKFFAQHPWPGTRHRETREYTESVASSEDFDIFDPFLAENEIETEFWTEELRLKFRFEFEKLVLLDYLMRNTDRNLDNWMIKICYEPCDNEEYYKSINLLSTNLTPNMSANSVDPAISQTSDFWKGPHFQIGAIDNSLAFPYKHPDSWRSFPYGWLSLPRSLFTQPFTEFTRQLFLHKLTSREWWEKLSDDLRNVFNQDLDFDEKMFSRQLSLVKGQAYNIVEVLKNPLMNIYDLLELPNLYVVEDVVRIEVNEPTSANSEEAEFGLPIKRDYGSILHPSCSQTFPPYPGSQLLQATPGRSFSSNAEALLPLNYITLLSKDSSSPKMLKDVIFERLQCASSNAVFSTC
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0016301 (kinase activity), GO:0052742 (phosphatidylinositol kinase activity), GO:0004430 (1-phosphatidylinositol 4-kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0019637 (organophosphate metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006793 (phosphorus metabolic process), GO:0046486 (glycerolipid metabolic process), GO:0006644 (phospholipid metabolic process), GO:0090407 (organophosphate biosynthetic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0008610 (lipid biosynthetic process), GO:0045017 (glycerolipid biosynthetic process), GO:0006650 (glycerophospholipid metabolic process), GO:0008654 (phospholipid biosynthetic process), GO:0046474 (glycerophospholipid biosynthetic process), GO:0006661 (phosphatidylinositol biosynthetic process), GO:0046488 (phosphatidylinositol metabolic process), GO:0046854 (phosphatidylinositol phosphate biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0032153 (cell division site), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0005773 (vacuole), GO:0031090 (organelle membrane), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0005774 (vacuolar membrane), GO:0098588 (bounding membrane of organelle), GO:0000322 (storage vacuole), GO:0000324 (fungal-type vacuole), GO:0098852 (lytic vacuole membrane), GO:0000329 (fungal-type vacuole membrane)