Protein: Ras-related protein Rab (F7F483)
Organism: Rattus norvegicus (Rat)
Function: The small GTPases Rab are key regulators in vesicle trafficking
Subcellular location: Membrane; Lipid- anchor
InterPro domains:
- IPR005225: Small GTP-binding domain (domain) [10-170]
- IPR001806: Small GTPase (family) [1-211]
- IPR030697: Ras-related protein Rab29/Rab38/Rab32 (family) [10-208]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [3-193]
Sequence:
MQTPHKEHLYKLLVIGDLGVGKTSIIKRYVHQNFSSHYRATIGVDFALKVLHWDPETVVRLQLWDIAGQERFGNMTRVYYREAMGAFIVFDVTRPATFEAVAKWKNDLDSKLTLPNGKPVSVVLLANKCDQGKDVLVNNGLKMDQFCKEHGFVGWFETSAKENINIDEASRCLVKHILANECDFIESIEPDIVKPHLTSPKVVSCSGCAKS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0016787 (hydrolase activity), GO:0043167 (ion binding), GO:0097367 (carbohydrate derivative binding), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:1901265 (nucleoside phosphate binding), GO:0043168 (anion binding), GO:0000166 (nucleotide binding), GO:0032553 (ribonucleotide binding), GO:0017076 (purine nucleotide binding), GO:0035639 (purine ribonucleoside triphosphate binding), GO:0019003 (GDP binding), GO:0032555 (purine ribonucleotide binding), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016462 (pyrophosphatase activity), GO:0005525 (GTP binding), GO:0019001 (guanyl nucleotide binding), GO:0032561 (guanyl ribonucleotide binding), GO:0017111 (ribonucleoside triphosphate phosphatase activity), GO:0003924 (GTPase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0048522 (positive regulation of cellular process), GO:0019222 (regulation of metabolic process), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:1903829 (positive regulation of protein localization), GO:0031325 (positive regulation of cellular metabolic process), GO:0060341 (regulation of cellular localization), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0016043 (cellular component organization), GO:0031323 (regulation of cellular metabolic process), GO:0043455 (regulation of secondary metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0045834 (positive regulation of lipid metabolic process), GO:0009891 (positive regulation of biosynthetic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:1900376 (regulation of secondary metabolite biosynthetic process), GO:1900378 (positive regulation of secondary metabolite biosynthetic process), GO:0010562 (positive regulation of phosphorus metabolic process), GO:1904377 (positive regulation of protein localization to cell periphery), GO:0010256 (endomembrane system organization), GO:0031326 (regulation of cellular biosynthetic process), GO:0046889 (positive regulation of lipid biosynthetic process), GO:0032880 (regulation of protein localization), GO:0006996 (organelle organization), GO:0019216 (regulation of lipid metabolic process), GO:0031328 (positive regulation of cellular biosynthetic process), GO:1903727 (positive regulation of phospholipid metabolic process), GO:0051174 (regulation of phosphorus metabolic process), GO:0046890 (regulation of lipid biosynthetic process), GO:0033363 (secretory granule organization), GO:1903725 (regulation of phospholipid metabolic process), GO:0048023 (positive regulation of melanin biosynthetic process), GO:0048021 (regulation of melanin biosynthetic process), GO:0016050 (vesicle organization), GO:0045937 (positive regulation of phosphate metabolic process), GO:1904375 (regulation of protein localization to cell periphery), GO:0071073 (positive regulation of phospholipid biosynthetic process), GO:0071071 (regulation of phospholipid biosynthetic process), GO:0019220 (regulation of phosphate metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0044297 (cell body), GO:0005829 (cytosol), GO:0048471 (perinuclear region of cytoplasm), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0005783 (endoplasmic reticulum), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0048770 (pigment granule), GO:0031982 (vesicle), GO:0042470 (melanosome), GO:0097708 (intracellular vesicle)