Protein: Signal peptide, CUB and EGF-like domain-containing protein 1 isoform 1 precursor (A0A8M1PAA2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted
InterPro domains:
- IPR000152: EGF-type aspartate/asparagine hydroxylation site (ptm) [47-414]
- IPR000742: EGF-like domain (domain) [30-810]
- IPR026823: Complement Clr-like EGF domain (domain) [94-116]
- IPR018097: EGF-like calcium-binding, conserved site (conserved_site) [113-412]
- IPR009030: Growth factor receptor cysteine-rich domain superfamily (homologous_superfamily) [24-834]
- IPR049883: NOTCH1 EGF-like calcium-binding domain (domain) [349-379]
- IPR052071: Signal peptide, CUB and EGF-like domain-containing protein (family) [5-1024]
- IPR011641: Tyrosine-protein kinase ephrin type A/B receptor-like (domain) [672-829]
- IPR024731: NELL2-like, EGF domain (domain) [34-69]
- IPR035914: Spermadhesin, CUB domain superfamily (homologous_superfamily) [834-952]
- IPR000859: CUB domain (domain) [834-946]
- IPR001881: EGF-like calcium-binding domain (domain) [30-428]
Sequence:
MGPACFSWEVCLLFLLINTLDVMGNVGVPDADECSEATDDCHIDALCQNTPKSFKCICKTGYKGDGKHCEDIDECENDYNGGCVHDCINIPGNYRCTCYDGFMLADDGHNCLDVDECLDNNGGCQQICVNTMGSYECQCKDGFFLSDNQHTCIHRSDDGMNCMNKDHGCAHICREITKGGVACECRPGFELAENQRDCKLTCNYGNGGCQHTCDDTDVGPICGCHQKYALHSDSKTCIEKDEAAIESSEFNTTSVADVDKRVKRRLLMETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDIDECLENNGGCDHFCRNTVGSFECSCQKGHKLLTNERTCQDIDECSFERTCDHVCINYPGSFECVCHKGYSLYGFTHCGDIDECSINNGSCEHGCVNTPGSYECVCPPGQKLHWNKKDCVEAVKCLQNGKPPPRAQLSCTKTGGGEVCSLSCPSNALFLADSENSYTLSCGVPVQPGKAPLKRNITTSSSSSLQTCTEMLAQPVKQKARFKIKDAKCHMRPRNKEKHRDMGKQGLQAGQFPCTDDCQVTFVNLKCDSSKKRRRGRKSPSKEVSHITAEFEMEMKEEEASESCNLDCVREKTKQRLQNAMRTLRKSISKQQFYIQFSGTAYEVAQHALRHTTEGDETCSIGQVFTDGKCVSCVVGTFYSGEQEQCVMCPLGTYQDREGQLSCEPCPRTEGQGIAGAKNVSECGGQCPAGQFSSDGFRPCQPCQLGTFQPEPGRVLCFPCGGGLMTKHTGSTSFRDCEAKVHCALGHYYNATTHRCIRCPAGTYQSESGQNYCITCPGNTTTDFDGANNVSHCKNQICGGELGDFMGYIESPNYPGDYPSNVDCVWTINPPNKRRILIVVPEIFLPIEDECGDVLVMRKSALPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTVQESKEMFPRSFIKLLRSKVSRFLRPYK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048513 (animal organ development), GO:0070848 (response to growth factor), GO:0071495 (cellular response to endogenous stimulus), GO:0009790 (embryo development), GO:0007166 (cell surface receptor signaling pathway), GO:0030097 (hemopoiesis), GO:0048568 (embryonic organ development), GO:0007224 (smoothened signaling pathway), GO:0007167 (enzyme-linked receptor protein signaling pathway), GO:0071772 (response to BMP), GO:0071363 (cellular response to growth factor stimulus), GO:0007178 (transmembrane receptor protein serine/threonine kinase signaling pathway), GO:0071773 (cellular response to BMP stimulus), GO:0035162 (embryonic hemopoiesis), GO:0030509 (BMP signaling pathway), GO:0060215 (primitive hemopoiesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)