Protein: receptor protein serine/threonine kinase (A0A8M2B949)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Single- pass type I membrane protein
InterPro domains:
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [345-357]
- IPR000472: Activin types I and II receptor domain (domain) [32-105]
- IPR001245: Serine-threonine/tyrosine-protein kinase, catalytic domain (domain) [222-507]
- IPR000719: Protein kinase domain (domain) [221-511]
- IPR003605: GS domain (domain) [191-221]
- IPR000333: Ser/Thr protein kinase, TGFB receptor (family) [18-513]
- IPR017441: Protein kinase, ATP binding site (binding_site) [227-248]
- IPR045860: Snake toxin-like superfamily (homologous_superfamily) [29-108]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [200-508]
Sequence:
MLRDGNVAVMPPRRTAVALLALCGLLAVGDALKCNCTACESTGYVCETDGACMASTSYINGQEEQQVRICIPRVSLVPPGQPIYCLSAKGLLNTHCCYTDFCNSINLQIPNGSSTGQTQYLSNVWGIADGKGGSWGPVELVAVIAGPVFLFCLLLIVGVLLFQHHQRNYNHRQRLDVEDPSCDHLYLAKDKTLQDLIFDLSTSGSGSGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQTIMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNHYSVTIEGMIKLSLSAASGLAHLHMEILGTQGKPGIAHRDLKSKNILVKKNGTCAIADLGLAVRHESITDTIDIAPNQRVGTKRYMAPEVLDETINMKHFDSFKCADIYALGLVYWEIARRCNAGGIHEDYQLPYYDLVPSDPSIEEMRKVVCDQRLRPNVPNWWQSYEALRVMGKIMRECWYANGAARLTALRIKKTLSQLSVQEDIKI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048589 (developmental growth), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0007389 (pattern specification process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0045165 (cell fate commitment), GO:0001704 (formation of primary germ layer), GO:0001709 (cell fate determination), GO:0048598 (embryonic morphogenesis), GO:0048729 (tissue morphogenesis), GO:0009888 (tissue development), GO:0003002 (regionalization), GO:0030154 (cell differentiation), GO:0009790 (embryo development), GO:0042246 (tissue regeneration), GO:0031099 (regeneration), GO:0007492 (endoderm development), GO:0001706 (endoderm formation), GO:0001707 (mesoderm formation), GO:0007369 (gastrulation), GO:0048332 (mesoderm morphogenesis), GO:0009953 (dorsal/ventral pattern formation), GO:0007498 (mesoderm development), GO:0060795 (cell fate commitment involved in formation of primary germ layer), GO:0035987 (endodermal cell differentiation), GO:0031101 (fin regeneration), GO:0001711 (endodermal cell fate commitment)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0043235 (receptor complex), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:0098802 (plasma membrane signaling receptor complex), GO:0098797 (plasma membrane protein complex), GO:0005886 (plasma membrane)