Protein: Chloride channel protein (A6IU39)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Multi-pass membrane protein
InterPro domains:
- IPR001807: Chloride channel (family) [141-590]
- IPR046342: CBS domain superfamily (homologous_superfamily) [592-867]
- IPR014743: Chloride channel, core (homologous_superfamily) [71-592]
- IPR002248: Chloride channel ClC-6 (family) [2-223]
- IPR051280: Voltage-gated chloride channel/antiporter (family) [17-858]
- IPR000644: CBS domain (domain) [602-869]
Sequence:
MAGCRGSVCCCCRWCCCCGERESRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDPYLEVLETMDNKKGRRHEAVKWMVVFAIGVCTGLVGLFVDFSVRLFTQLKFGVVQTSVEECSQKGCLALSLLELLGFNLTFVFLASLLVLIEPVAAGSGIPEIKCYLNGVKVPGIVRLRTLLCKVFGVLFSVAGGLFVGKEGPMIHSGAVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWKVLFCSMSATFTLNFFRSGIQFGSWGAFQLPGLLNFGEFKCSDSDKKCHLWTAMDLGFFVVMGVIGGLLGATFNCLNKRLAKYRMRNVHPKPKLVRVLESLLVSLVTTVVVFVASMVLGECRQMSSTSQTGNGSFQLQVTSEDVNSTIKTFFCPNDTYNDMATLFFNSQESAILQLFHQDGTFSPVTLALFFALYFLMACWTFGTSVPSGLFVPSLLCGAAFGRLVANVLKSYIGLGHLYSGTFALIGAAAFLGGVVRMTISLTVILIESTNEITYGLPIMVTLMVAKWTGDFFNKGIYDIHIGLRGVPLLEWETEVEMDRLRASDIMEPNLTYVYPHTRIQSLVSILRTTVHHAFPVVTENRGNEKEFMKGNQLISNNIKFKKSSILTRAGEQRKRGQSMKSYPSSELRNVCDEHVASEEPAEKEDLLQQMLERRYTPYPNLYPDQSPSEDWTMEERFRPLTFHGLVLRSQLVTLLVRGVCYSESQSSASQPRLSYAEMAEDYPRFPDIHDLDLTLLNPRMIVDVTPYMNPSPFTVSPNTHVSQVFNLFRTMGLRHLPVVNAVGEIVGIITRHNLTTEFLQARLRQHYQTL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0008509 (monoatomic anion transmembrane transporter activity), GO:0015103 (inorganic anion transmembrane transporter activity), GO:0015108 (chloride transmembrane transporter activity), GO:0015267 (channel activity), GO:0015291 (secondary active transmembrane transporter activity), GO:0015297 (antiporter activity), GO:0005254 (chloride channel activity), GO:0022839 (monoatomic ion gated channel activity), GO:0005253 (monoatomic anion channel activity), GO:0022836 (gated channel activity), GO:0005244 (voltage-gated monoatomic ion channel activity), GO:0008308 (voltage-gated monoatomic anion channel activity), GO:0022832 (voltage-gated channel activity), GO:0005247 (voltage-gated chloride channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0009612 (response to mechanical stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle)