Protein: Cathelicidin antimicrobial peptide (A6I3C7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted
InterPro domains:
- IPR046350: Cystatin superfamily (homologous_superfamily) [32-125]
- IPR018216: Cathelicidin, conserved site (conserved_site) [34-100]
- IPR001894: Cathelicidin-like (family) [10-147]
- IPR022746: Cathelicidin, antimicrobial peptide, C-terminal (domain) [142-168]
Sequence:
MQPHRDVPSLWRSLSLLLLLGLGLPLAVSQTLSYREAVLRAVDDFNQQSLDTNLYRLLDLDSEPQGDEDPDTPKYVRFRVKETVCSKASQQLPEQCAFKEQGVVKQCMGTVTLNQAAESFDISCDAPGIQPFRFKKISRLAGLLRKGGEKFGEKLRKIGQKIKDFFQKLAPEIEQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097367 (carbohydrate derivative binding), GO:0008289 (lipid binding), GO:0001530 (lipopolysaccharide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0051240 (positive regulation of multicellular organismal process), GO:0051239 (regulation of multicellular organismal process), GO:0050793 (regulation of developmental process), GO:0009607 (response to biotic stimulus), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0051094 (positive regulation of developmental process), GO:0051707 (response to other organism), GO:0048522 (positive regulation of cellular process), GO:0043207 (response to external biotic stimulus), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0006952 (defense response), GO:0071495 (cellular response to endogenous stimulus), GO:0060255 (regulation of macromolecule metabolic process), GO:1901700 (response to oxygen-containing compound), GO:0071216 (cellular response to biotic stimulus), GO:0010033 (response to organic substance), GO:0098542 (defense response to other organism), GO:1904018 (positive regulation of vasculature development), GO:2000026 (regulation of multicellular organismal development), GO:0042127 (regulation of cell population proliferation), GO:1901698 (response to nitrogen compound), GO:0031325 (positive regulation of cellular metabolic process), GO:0070887 (cellular response to chemical stimulus), GO:0009617 (response to bacterium), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0008284 (positive regulation of cell population proliferation), GO:0071417 (cellular response to organonitrogen compound), GO:0034097 (response to cytokine), GO:0071219 (cellular response to molecule of bacterial origin), GO:0032496 (response to lipopolysaccharide), GO:0010562 (positive regulation of phosphorus metabolic process), GO:0051246 (regulation of protein metabolic process), GO:0071310 (cellular response to organic substance), GO:1901342 (regulation of vasculature development), GO:0045766 (positive regulation of angiogenesis), GO:0032494 (response to peptidoglycan), GO:1901699 (cellular response to nitrogen compound), GO:0002237 (response to molecule of bacterial origin), GO:0010243 (response to organonitrogen compound), GO:0033993 (response to lipid), GO:0042742 (defense response to bacterium), GO:0051247 (positive regulation of protein metabolic process), GO:0045765 (regulation of angiogenesis), GO:1901701 (cellular response to oxygen-containing compound), GO:0051174 (regulation of phosphorus metabolic process), GO:0071222 (cellular response to lipopolysaccharide), GO:0031399 (regulation of protein modification process), GO:0070555 (response to interleukin-1), GO:0045937 (positive regulation of phosphate metabolic process), GO:0071345 (cellular response to cytokine stimulus), GO:0019220 (regulation of phosphate metabolic process), GO:0071396 (cellular response to lipid), GO:0070741 (response to interleukin-6), GO:0050829 (defense response to Gram-negative bacterium), GO:0034612 (response to tumor necrosis factor), GO:0050830 (defense response to Gram-positive bacterium), GO:0031401 (positive regulation of protein modification process), GO:0042325 (regulation of phosphorylation), GO:0001932 (regulation of protein phosphorylation), GO:0071347 (cellular response to interleukin-1), GO:0042327 (positive regulation of phosphorylation), GO:0071354 (cellular response to interleukin-6), GO:0071356 (cellular response to tumor necrosis factor), GO:0001934 (positive regulation of protein phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:0042995 (cell projection), GO:0005576 (extracellular region), GO:0005615 (extracellular space)