Protein: RCG41127, isoform CRA_c (A6KIM8)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR056887: Nesprin-1/2 domain (domain) [369-473]
- IPR002017: Spectrin repeat (repeat) [43-700]
- IPR012315: KASH domain (domain) [891-950]
- IPR018159: Spectrin/alpha-actinin (repeat) [44-813]
Sequence:
MVVAEDLRALRMAEDGSVDADLPDCDCDVSRQVKKLKETLVAVQQLDKNMGSLRIWLAHMESELAKPIVYDSCNSEEIQKKLSEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLEISERTAAFPSSSGVLYTVAKEELKKFEAFQRQVHESLTQLELINKQYRRLARENRTDSACSLRQMAHGGNQRWDDLQKRVTSILRRLKHFISQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHSKIEQIIAQGEQLIEKSEPLDAAVIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDHDLSDRELDLEDSMALSDLHWQDPSEDGMPSPQPSSNPSLSLPQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESASRTLPSEDEEGEEDKEFYLRGAVGLSGDPTSLESQMRQLDKALDDSRFQIQQTANILRGKTPTGPDLGTSYKGYMKLLGECSGSIDSVRRLEHKLAEEESFPGFTNPTSTETQPAGVIDRWELLQAQAMSKELKMKQNLQKWQQFNSDLNNICAWLGETEEELDRLQHLALSTDIHTIKSHIKKLKELQKALDHRKAIILSINLCSSEFTQADSKESHDLQDRLSQMNRRWDRVCSLLEDWRGSLQDALMQCQDFHEMTHALLLLLENTDRRKNEIVPIDSTLDPETLQDHHTQLTQIKQELLKSQLRVASLQNMSRQLLVNAEGSDCLEAKEKVHVIGNRLKLLLKEVSRHIKDLEKLLGMSSSQQDLSSWSSADEVDTSGSVSPTSGRSTPNRQKSPRGKCSLSQPGPSVSSPKSRSTKGGSDSSLSETRPARAGRDFLFRVLRAALPIQLLLLLLIGLTSRVPISEEDYSCALSNNFARSFHPMLRYTNGPPPL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0005102 (signaling receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0048869 (cellular developmental process), GO:0009628 (response to abiotic stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0032879 (regulation of localization), GO:0051239 (regulation of multicellular organismal process), GO:0051050 (positive regulation of transport), GO:0065008 (regulation of biological quality), GO:0050793 (regulation of developmental process), GO:0090394 (negative regulation of excitatory postsynaptic potential), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0050773 (regulation of dendrite development), GO:0099149 (regulation of postsynaptic neurotransmitter receptor internalization), GO:0051049 (regulation of transport), GO:0060548 (negative regulation of cell death), GO:0030154 (cell differentiation), GO:0009314 (response to radiation), GO:0048731 (system development), GO:0044057 (regulation of system process), GO:0048513 (animal organ development), GO:0009966 (regulation of signal transduction), GO:0060627 (regulation of vesicle-mediated transport), GO:0051130 (positive regulation of cellular component organization), GO:0061061 (muscle structure development), GO:0042127 (regulation of cell population proliferation), GO:0010941 (regulation of cell death), GO:0009888 (tissue development), GO:0010646 (regulation of cell communication), GO:0060322 (head development), GO:0042391 (regulation of membrane potential), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0099177 (regulation of trans-synaptic signaling), GO:0045807 (positive regulation of endocytosis), GO:0051128 (regulation of cellular component organization), GO:0008284 (positive regulation of cell population proliferation), GO:0030100 (regulation of endocytosis), GO:0009416 (response to light stimulus), GO:0031344 (regulation of cell projection organization), GO:0043069 (negative regulation of programmed cell death), GO:0043067 (regulation of programmed cell death), GO:0098815 (modulation of excitatory postsynaptic potential), GO:0050804 (modulation of chemical synaptic transmission), GO:0048814 (regulation of dendrite morphogenesis), GO:0002053 (positive regulation of mesenchymal cell proliferation), GO:0048260 (positive regulation of receptor-mediated endocytosis), GO:0010464 (regulation of mesenchymal cell proliferation), GO:0007420 (brain development), GO:0007399 (nervous system development), GO:0042692 (muscle cell differentiation), GO:0072359 (circulatory system development), GO:0031644 (regulation of nervous system process), GO:0060537 (muscle tissue development), GO:0007507 (heart development), GO:0033043 (regulation of organelle organization), GO:0007417 (central nervous system development), GO:0035051 (cardiocyte differentiation), GO:0048259 (regulation of receptor-mediated endocytosis), GO:0042981 (regulation of apoptotic process), GO:0014706 (striated muscle tissue development), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0048738 (cardiac muscle tissue development), GO:0043066 (negative regulation of apoptotic process), GO:0055007 (cardiac muscle cell differentiation), GO:0051146 (striated muscle cell differentiation), GO:0002090 (regulation of receptor internalization), GO:2001053 (regulation of mesenchymal cell apoptotic process), GO:0010975 (regulation of neuron projection development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0044327 (dendritic spine head), GO:0048471 (perinuclear region of cytoplasm), GO:0030054 (cell junction), GO:0030496 (midbody), GO:0031975 (envelope), GO:0098794 (postsynapse), GO:0036477 (somatodendritic compartment), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0043228 (non-membrane-bounded organelle), GO:0005794 (Golgi apparatus), GO:0043197 (dendritic spine), GO:0005635 (nuclear envelope), GO:0097447 (dendritic tree), GO:0043227 (membrane-bounded organelle), GO:0031965 (nuclear membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0030425 (dendrite), GO:0043005 (neuron projection), GO:0005634 (nucleus), GO:0005856 (cytoskeleton), GO:0005819 (spindle), GO:0044309 (neuron spine), GO:0015630 (microtubule cytoskeleton)