Protein: Kinesin-like protein (A0A8I5KQ45)
Organism: Homo sapiens (Human)
InterPro domains:
- IPR001752: Kinesin motor domain (domain) [41-376]
- IPR019821: Kinesin motor domain, conserved site (conserved_site) [268-279]
- IPR036961: Kinesin motor domain superfamily (homologous_superfamily) [31-369]
- IPR027640: Kinesin-like protein (family) [42-381]
- IPR010994: RuvA domain 2-like (homologous_superfamily) [554-644]
- IPR003583: Helix-hairpin-helix DNA-binding motif, class 1 (domain) [586-635]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [43-476]
Sequence:
MAAGGSTQQRRREMAAASAAAISGAGRCRLSKIGATRRPPPARVRVAVRLRPFVDGTAGASDPPCVRGMDSCSLEIANWRNHQETLKYQFDAFYGERSTQQDIYAGSVQPILRHLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLTREEGAEGRPWALSVTMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLSQKPISSFADFERHFLPASRNRTVGATRLNQRSSRSHAVLLVKVDQRERLAPFRQREGKLYLIDLAGSEDNRRTGNKGLRLKESGAINTSLFVLGKVVDALNQGLPRVPYRDSKLTRLLQDSLGGSAHSILIANIAPERRFYLDTVSALNFAARSKEVINRPFTNESLQPHEAKRARGPEEEEIGSPEPMAAPASASQKLSPLQKLSSMDPAMLERLLSLDRLLASQGSQGAPLLSTPKRERMVLMKTVEEKDLEIERLKTKQKELEAKMLAQKAEEKENHCPTMLRPLSHRTVTGAKPLKKAVVMPLQLIQEQAASPNAEIHILKNKGRKRKLESLDALEPEEKAEDCWELQISPELLAHGRQKILDLLNEGSARDLRSLQRIGPKKAQLIVGWRELHGPFSQVEDLERVEGITGKQMESFLKANILGLAAGQRCGAS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003774 (cytoskeletal motor activity), GO:0140657 (ATP-dependent activity), GO:0003777 (microtubule motor activity), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0051641 (cellular localization), GO:0023057 (negative regulation of signaling), GO:0042221 (response to chemical), GO:0071840 (cellular component organization or biogenesis), GO:0033036 (macromolecule localization), GO:0008219 (cell death), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0048522 (positive regulation of cellular process), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0090068 (positive regulation of cell cycle process), GO:0012501 (programmed cell death), GO:0035556 (intracellular signal transduction), GO:0009966 (regulation of signal transduction), GO:0051130 (positive regulation of cellular component organization), GO:0010948 (negative regulation of cell cycle process), GO:0044089 (positive regulation of cellular component biogenesis), GO:0010033 (response to organic substance), GO:0045787 (positive regulation of cell cycle), GO:0051726 (regulation of cell cycle), GO:0010646 (regulation of cell communication), GO:0070887 (cellular response to chemical stimulus), GO:0070727 (cellular macromolecule localization), GO:0045786 (negative regulation of cell cycle), GO:0016043 (cellular component organization), GO:0051128 (regulation of cellular component organization), GO:0010564 (regulation of cell cycle process), GO:0051984 (positive regulation of chromosome segregation), GO:0007346 (regulation of mitotic cell cycle), GO:0007088 (regulation of mitotic nuclear division), GO:0000075 (cell cycle checkpoint signaling), GO:1901989 (positive regulation of cell cycle phase transition), GO:0071310 (cellular response to organic substance), GO:1905818 (regulation of chromosome separation), GO:1902532 (negative regulation of intracellular signal transduction), GO:1905820 (positive regulation of chromosome separation), GO:0045931 (positive regulation of mitotic cell cycle), GO:0051983 (regulation of chromosome segregation), GO:1901987 (regulation of cell cycle phase transition), GO:0006915 (apoptotic process), GO:0045840 (positive regulation of mitotic nuclear division), GO:0033043 (regulation of organelle organization), GO:0008104 (protein localization), GO:0010638 (positive regulation of organelle organization), GO:1901701 (cellular response to oxygen-containing compound), GO:1902531 (regulation of intracellular signal transduction), GO:0031334 (positive regulation of protein-containing complex assembly), GO:0090266 (regulation of mitotic cell cycle spindle assembly checkpoint), GO:0051783 (regulation of nuclear division), GO:0033365 (protein localization to organelle), GO:0010965 (regulation of mitotic sister chromatid separation), GO:1903504 (regulation of mitotic spindle checkpoint), GO:1901970 (positive regulation of mitotic sister chromatid separation), GO:0033045 (regulation of sister chromatid segregation), GO:0062033 (positive regulation of mitotic sister chromatid segregation), GO:1902101 (positive regulation of metaphase/anaphase transition of cell cycle), GO:0045842 (positive regulation of mitotic metaphase/anaphase transition), GO:1901977 (negative regulation of cell cycle checkpoint), GO:1902099 (regulation of metaphase/anaphase transition of cell cycle), GO:2001252 (positive regulation of chromosome organization), GO:0033047 (regulation of mitotic sister chromatid segregation), GO:1901992 (positive regulation of mitotic cell cycle phase transition), GO:1901990 (regulation of mitotic cell cycle phase transition), GO:0051785 (positive regulation of nuclear division), GO:0033044 (regulation of chromosome organization), GO:1901976 (regulation of cell cycle checkpoint), GO:0034502 (protein localization to chromosome), GO:0090231 (regulation of spindle checkpoint), GO:0030071 (regulation of mitotic metaphase/anaphase transition), GO:0071459 (protein localization to chromosome, centromeric region), GO:1903083 (protein localization to condensed chromosome), GO:0034501 (protein localization to kinetochore)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0016604 (nuclear body), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0016607 (nuclear speck), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)