lokahq/bioreason-rl huggingface dataset:
Protein: Homeobox protein (A6K0R2)
Organism: Rattus norvegicus (Rat)
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis
Subcellular location: Nucleus
InterPro domains:
- IPR006711: Hox9, N-terminal activation domain (domain) [1-192]
- IPR017970: Homeobox, conserved site (conserved_site) [238-261]
- IPR001356: Homeodomain (domain) [203-267]
- IPR020479: Homeodomain, metazoa (domain) [227-261]
- IPR017112: Homeobox protein HXA9/HXB9/HXC9 (family) [1-270]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [190-265]
Sequence:
MATTGALGNYYVDSFLLGADAADELGAGRYAPGALGQPQRQAAALAEHPDFSPCSFQSKAAVFGASWNPVHAAGANAVPAAVYHHHHHPYVHPQAPVAAAAPDGRYMRSWLEPTPGALSFAGLPSSRPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPPVDREKQPSEGAFSENNAENESGGDKPPIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0019899 (enzyme binding), GO:0003677 (DNA binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0050896 (response to stimulus), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0042221 (response to chemical), GO:0003006 (developmental process involved in reproduction), GO:0048608 (reproductive structure development), GO:1901700 (response to oxygen-containing compound), GO:0010033 (response to organic substance), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048732 (gland development), GO:0061458 (reproductive system development), GO:0001655 (urogenital system development), GO:0014070 (response to organic cyclic compound), GO:1901654 (response to ketone), GO:0033993 (response to lipid), GO:0030850 (prostate gland development), GO:0033574 (response to testosterone)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: RCG51062, isoform CRA_b (A6IYQ4)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR002843: ATPase, V0 complex, C/D subunit (family) [1-270]
- IPR016727: ATPase, V0 complex, subunit D (family) [1-274]
- IPR036079: V-type ATP synthase subunit C/D subunit superfamily (homologous_superfamily) [2-273]
Sequence:
MVVEFRHMRNHAYEPLASFLDFITYSYMIDNVILLITGTLHQRSIAELVPKCHPLGSFEQMEAVNIAQTPAELYNAILVDTPLAAFFQDCISEQDLDEMNIEIIRNTLYKAYLESFYKFCTLLGGTTADAMCPILEFEADRRAFIITINSFGTELSKEDRAKLFPHCGRLYPEGLAQLARADDYEQVKNVADYYPEYKLLFEGAGSNPGDKTLEDRFFEHEVKLNKLAFLNQFHFGVFYAFVKLKEQECRNIVWIAECIAQRHRAKIDNYIPIF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0150034 (distal axon), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0098793 (presynapse), GO:0071944 (cell periphery), GO:0030054 (cell junction), GO:0045177 (apical part of cell), GO:0044306 (neuron projection terminus), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0008021 (synaptic vesicle), GO:0120025 (plasma membrane bounded cell projection), GO:0043679 (axon terminus), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0016324 (apical plasma membrane), GO:0030133 (transport vesicle), GO:0098590 (plasma membrane region), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0030658 (transport vesicle membrane), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0012506 (vesicle membrane), GO:0070382 (exocytic vesicle), GO:0043005 (neuron projection), GO:0030672 (synaptic vesicle membrane), GO:0031982 (vesicle), GO:0030659 (cytoplasmic vesicle membrane), GO:0097708 (intracellular vesicle), GO:0099501 (exocytic vesicle membrane), GO:0030424 (axon)
Protein: Alpha-amylase (A6HV63)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR006048: Alpha-amylase/branching enzyme, C-terminal all beta (domain) [437-520]
- IPR017853: Glycoside hydrolase superfamily (homologous_superfamily) [29-426]
- IPR006046: Alpha amylase (family) [85-329]
- IPR031319: Alpha-amylase, C-terminal domain (domain) [434-522]
- IPR013780: Glycosyl hydrolase, all-beta (homologous_superfamily) [431-523]
- IPR006047: Glycosyl hydrolase family 13, catalytic domain (domain) [38-425]
Sequence:
MKIREYCQHHSRMKFFLLLSLIGLCWAQYDPHTFYGRSSIVHLFEWRWVDIAKECERYLAPNGFGGVQVSPPNENIVVNSPFRPWWERYQPISYKICSRSGNEDEFRDMVNRCNNVGVRIYVDAVINHMCGVGAEAGQSSTCGSYFNPNNRDFPGVPYSGFDFNDGKCKTGSGGIENYNDAAQVRDCRLSGLLDLALEKDYVRTKVADYMNHLIDIGVAGFRLDASKHMWPGDIKAVLDKLHNLNTKWFSEGSKPFIYQEVIDLGGEAVSSNEYFGNGRVTEFKYGAKLGKVLRKWDGEKMAYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGSSILTFWDARLYKMAVGFMLAHPYGFTRVMSSFHWPRYFENGKDVNDWVGPPNNNGATKEVTINSDSTCGNDWVCEHRWRQIRNMVAFRNVVNGQPFANWWDNGSNQVAFGRGNKGFIVFNNDDWDLSTTLQTGLPAGTYCDVISGDKVDGNCTGIKVYVGSDGNAYFSISNSAEDPFIAIHVESKI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds), GO:0016160 (amylase activity), GO:0004556 (alpha-amylase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:0005975 (carbohydrate metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Tissue factor pathway inhibitor (A6K2A8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted
InterPro domains:
- IPR008296: Tissue factor pathway inhibitor-like (family) [1-220]
- IPR036880: Pancreatic trypsin inhibitor Kunitz domain superfamily (homologous_superfamily) [25-212]
- IPR050098: Tissue factor pathway inhibitor/Kunitz-type serine protease inhibitor-like (family) [96-216]
- IPR020901: Proteinase inhibitor I2, Kunitz, conserved site (conserved_site) [64-202]
- IPR002223: Pancreatic trypsin inhibitor Kunitz domain (domain) [33-207]
Sequence:
MDPATSLRLWNLPLLLVGSALGLASVSAQGNNLEICLLPLDMGPCKALIPKFYYDRDQKKCRRFKYGGCLGNANNFHSRKLCEHTCGNKEKVPWVCRSAVRTYPCDKPNTEFFFNLKTMTCEPLRPGLCSRTTNVFPEEAMCKSLCEPRKSIPSFCSSPKDEGLCSANVTRYYFNSRNKACETFTYTGCGGNENNFYYLDACNRACVKALKKPKRRKIGDFLPRFWKLRS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0009987 (cellular process), GO:0005201 (extracellular matrix structural constituent)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0034405 (response to fluid shear stress), GO:0033554 (cellular response to stress), GO:0071498 (cellular response to fluid shear stress)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (A6K8N5)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR006138: NADH-ubiquinone oxidoreductase, 20 Kd subunit (family) [68-189]
- IPR006137: NADH:ubiquinone oxidoreductase-like, 20kDa subunit (domain) [93-188]
Sequence:
MAALAAPGLLSVRILGLRTGTVAQLRRAHQSVAATGSPSSTQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPAAAEDQTRTEAEDLVPQVELPSRT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0002020 (protease binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0036477 (somatodendritic compartment), GO:0042995 (cell projection), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0044297 (cell body), GO:0043025 (neuronal cell body), GO:0005886 (plasma membrane), GO:0045202 (synapse), GO:0098590 (plasma membrane region), GO:0120025 (plasma membrane bounded cell projection), GO:0043005 (neuron projection), GO:0097060 (synaptic membrane)
Protein: Tetraspanin (A6K013)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Multi-pass membrane protein
InterPro domains:
- IPR000301: Tetraspanin, animals (family) [6-183]
- IPR018503: Tetraspanin, conserved site (conserved_site) [66-88]
- IPR048232: Tetraspanin-6/7, EC2 domain (domain) [110-199]
- IPR008952: Tetraspanin, EC2 domain superfamily (homologous_superfamily) [110-199]
- IPR018499: Tetraspanin/Peripherin (family) [15-207]
Sequence:
MASRRMETKPVITCLKTLLIIYSFVFWITGAILLAVGVWGKLTLGTYISLIAENSTNAPYVLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQNYNGKDERSRAVDHVQRSLSCCGVQNYTNWSSSPYFLEHGIPPSCCMNETDCNPLDLHNLTVAATKVNQKLIGMLLACCLSRFITANQYEMV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0065008 (regulation of biological quality), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0060627 (regulation of vesicle-mediated transport), GO:0099149 (regulation of postsynaptic neurotransmitter receptor internalization), GO:0051049 (regulation of transport), GO:0030100 (regulation of endocytosis), GO:0048259 (regulation of receptor-mediated endocytosis), GO:0002090 (regulation of receptor internalization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Mediator of RNA polymerase II transcription subunit 31 (A6HGE1)
Organism: Rattus norvegicus (Rat)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors
Subcellular location: Nucleus
InterPro domains:
- IPR038089: Mediator of RNA polymerase II, subunit Med31 superfamily (homologous_superfamily) [3-105]
- IPR008831: Mediator complex, subunit Med31 (family) [9-127]
Sequence:
MAAAVAMETDDAGNRLRFQLELEFVQCLANPNYLNFLAQRGYFKDKAFVNYLKYLLYWKEPEYAKYLKYPQCLHMLELLQYEHFRKELVNAQCAKFIDEQQILHWQHYSRKRMRLQQALAEQQQQNTTAGK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity), GO:0061659 (ubiquitin-like protein ligase activity), GO:0061630 (ubiquitin protein ligase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0070647 (protein modification by small protein conjugation or removal), GO:0032446 (protein modification by small protein conjugation), GO:0016567 (protein ubiquitination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0140535 (intracellular protein-containing complex), GO:1990234 (transferase complex), GO:0000151 (ubiquitin ligase complex)
Protein: PHD finger protein 1 (A6JJJ4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR031202: PHD finger protein 1, PHD finger 1 (domain) [89-139]
- IPR047399: PHD finger protein 1, Tudor domain (domain) [30-82]
- IPR019786: Zinc finger, PHD-type, conserved site (conserved_site) [90-139]
- IPR002999: Tudor domain (domain) [29-86]
- IPR040477: Lysine-specific demethylase 4-like, Tudor domain (domain) [34-69]
- IPR019787: Zinc finger, PHD-finger (domain) [87-142]
- IPR001965: Zinc finger, PHD-type (domain) [89-238]
- IPR047010: PHD finger protein 1, PHD finger 2 (domain) [188-239]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [85-142]
- IPR011011: Zinc finger, FYVE/PHD-type (homologous_superfamily) [83-254]
Sequence:
MAQLPRLSRLGAPSLWDPASPAPTSGPRPRLWEGQDVLARWTDGLLYLGTIKKVDSAREVCLVQFEDDSQFLVLWKDISPAALPGEELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCHVPRAPAPGEGEGSSWVCRQCVFAIATKRGGALKKGPYARAMLGMKLSLPYGLKGLDWDAGHLSNRQQSYCYCGGPGEWNLKMLQCRSCLQWFHEACTQCLSKPLLYGDRFYEFECCVCRGGPEKVRRLQLRWVDVAHLVLYHLSVCCKKKYFDFDREILPFTSENWDSLLLGELSDTPKGERSSKLLSALNSHKDRFISGREIKKRKCLFGLHARTPPPVELLTGDGSPTSFPSGQGPGGGVSRPLGKRRKSEPEPLRRRQKGKVEELGPPTAAHSRHGSQEQRALQASESPPPPSPNQSYQGSSGYNFRPTDARCLPSSPIRMFASFHPSASTAGTSGDSEPPDRSPLELHIGFPTDIPKSSPHSVTASSSSVPALTPGLSRHSLPPSPLCRSLSPGTGGGVRGGVSYLSRGDPVRVLARRVRPDGSVQYLVELLTPLPFPLMLFCYSF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:1901700 (response to oxygen-containing compound), GO:0032526 (response to retinoic acid), GO:0033993 (response to lipid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Cell death-inducing DNAation factor, alpha subunit-like effector B (Predicted), isoform CRA_b (A6KH50)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR003508: CIDE-N domain (domain) [79-155]
Sequence:
MLDSSLTLPELRSQLYTKTQDFSLHTTEVPSPEAIGGRLAVSHPAMEYLSALSSNGLLRSVSTMSSELSRRVWNSAPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVVETLLLSGVLTLVLEEDGTAVETEDFFELLEDDTCLMALEQGQSWSPKSGMLSYGLGREKPKHSKDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHRQSHLHS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0046983 (protein dimerization activity), GO:0042803 (protein homodimerization activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0009991 (response to extracellular stimulus), GO:0038183 (bile acid signaling pathway), GO:0031667 (response to nutrient levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0048471 (perinuclear region of cytoplasm), GO:0005737 (cytoplasm)
Protein: LIM/homeobox protein Lhx3 (A6JTC6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR001781: Zinc finger, LIM-type (domain) [34-156]
- IPR049594: LIM/homeobox protein Lhx3/4-like, LIM domain 2 (domain) [95-150]
- IPR049593: LIM/homeobox protein Lhx3, LIM domain 1 (domain) [33-87]
- IPR050453: LIM/homeobox transcription factors (family) [30-263]
- IPR017970: Homeobox, conserved site (conserved_site) [195-218]
- IPR001356: Homeodomain (domain) [160-224]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [159-222]
Sequence:
MEARGELDPSRESAGGDLLLALLARRADLRREIPMCAGCDQHILDRFILKALDRHWHSKCLKCSDCHVPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGSSKSDKDSIQEGQDSDAEVSFTDEPSMADMGTANGLYSSLGEPAPALGRPVGGLGSFTLEHGGLAGPEQFRELRPGSPYGIPPSPAAPQSLPGPQPLLSSLVYPDTNLGLVPSGPPGGPPPMRVLAGNGPSSDLSTESSGGYPDFPASPASWLDEVDHAQF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding), GO:0000987 (cis-regulatory region sequence-specific DNA binding), GO:0000977 (RNA polymerase II transcription regulatory region sequence-specific DNA binding), GO:0000978 (RNA polymerase II cis-regulatory region sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0035295 (tube development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0030324 (lung development), GO:0030323 (respiratory tube development), GO:0060541 (respiratory system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: T-cell surface glycoprotein CD3 zeta chain (A6IDI4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein
InterPro domains:
- IPR024128: T-cell surface glycoprotein CD3 zeta subunit (family) [1-146]
- IPR021663: T-cell surface glycoprotein CD3 zeta subunit/High affinity IgE receptor gamma subunit (family) [28-58]
- IPR003110: Phosphorylated immunoreceptor signalling ITAM (repeat) [69-129]
Sequence:
MKWTASVLACILQVQFPGAEAQSFGLLDPKLCYMLDGILFIYGVIVTALYLRAKFSRSADAAAYLQDPNQLYNELNLGRREEYDVLDKKRPRDPEMGGKQQRRRNPQEGVYNALQKDKMAEAYSEIGMKGERRRGKGHDGLYQDSHFQAVLVTEKRKKAQKGPWVETPPQR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007166 (cell surface receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0043235 (receptor complex), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:0098802 (plasma membrane signaling receptor complex), GO:0098797 (plasma membrane protein complex), GO:0005886 (plasma membrane), GO:0042101 (T cell receptor complex)