Protein: receptor protein serine/threonine kinase (A0A8M2BD77)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR000472: Activin types I and II receptor domain (domain) [58-129]
- IPR000719: Protein kinase domain (domain) [208-509]
- IPR000333: Ser/Thr protein kinase, TGFB receptor (family) [24-508]
- IPR017441: Protein kinase, ATP binding site (binding_site) [214-235]
- IPR045860: Snake toxin-like superfamily (homologous_superfamily) [31-134]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [192-505]
Sequence:
MAVEGRITILDVGLIAMVVLLGPVAAAQSEQRECAYAEQPQGLAERIGGRGEGLVFHENSTIRCYQGHRCFGLWGKKNNGVVLVKQGCWTNVGDHQECYDRCVVTNPPSVAQNGTYRFCCCNKDMCNLNFTEDFPPPSPTTAQPLQSRRLHREEVIVVALATVSMVAVLVILLFFGYRMLRGRGKHSLHTLNILETALSPPSLDLDNLTLQELIGRGRYGTVYRASLDDRSVAVKVFISANRQQFTNERMIYRLLLDHENIARFLESEERVGTEGRTEFLLLLEFYPHGSLCTYLSGRTVDWLSCCRLALSVTRGLAYLHTEIQRGDVYKPAVSHRDLNSRNVLVKTDGSCVISDFGLSMILTGKRPPGHGEEDNSAISEVGTVRYMAPEVLEGAVNLRDCESALKQVDVYALGLVYWETFMRCADLFPGETVPAFQLAFQAEVGNHPTIEDMQALVSREKERPKFPEAWKENSLTVHSLKETMEDCWDQDAEARLTAQCAEERLAELLLIWDREKSASPALNHSTALYNHRNFSAGRQTPKVGSVLEHSSTNTEDHEGADKPLHNDTSVEQTSAGGTNPAEKKKNCINYEWQQAQSRQSGTESSSATPVSESCNATHPPPVATNLCAQLTREDLEIPKLDPSEVQRNMRESSDESLMEHSQKQFCSPETSASHGPFYPLMKMVSEVSGSQGSSRHGDTPITILPKQQNVPKRPSSLSLHVKPGKTSTSTSSSLRMKFGKLGKSNLKKVEMGVAKSSVVNATHEARLITVANNDAAAAMNKYATEPAAESAGSSANEDLTFGLLNTSPDEQEPLLRREAHPDNANNNNSNNNNGEGDGDGETEGGGEGGENNESVGPTGDASSSSTVEPVVLPGPCSASTAIPPQAQSQTQTHGEALLRQNRVRRPERPNSLDLSITTLPLLGGRSVGDGTEGSGDKIKKRVKTPYALKKWRPASWVITTDTLDAEVNNNSRHGGGLGQNQNQAGTSRPKSASAVYLGSRGGSRFSDPNDCDF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0060089 (molecular transducer activity), GO:0140096 (catalytic activity, acting on a protein), GO:0038023 (signaling receptor activity), GO:0016740 (transferase activity), GO:0004672 (protein kinase activity), GO:0004888 (transmembrane signaling receptor activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0019199 (transmembrane receptor protein kinase activity), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity), GO:0004675 (transmembrane receptor protein serine/threonine kinase activity), GO:0005024 (transforming growth factor beta receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0007389 (pattern specification process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0048729 (tissue morphogenesis), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0070848 (response to growth factor), GO:0071495 (cellular response to endogenous stimulus), GO:0009799 (specification of symmetry), GO:0001945 (lymph vessel development), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0009888 (tissue development), GO:0003002 (regionalization), GO:0009790 (embryo development), GO:0007166 (cell surface receptor signaling pathway), GO:0035239 (tube morphogenesis), GO:0060562 (epithelial tube morphogenesis), GO:0007167 (enzyme-linked receptor protein signaling pathway), GO:0048562 (embryonic organ morphogenesis), GO:0001944 (vasculature development), GO:0003143 (embryonic heart tube morphogenesis), GO:0002009 (morphogenesis of an epithelium), GO:0009855 (determination of bilateral symmetry), GO:0048568 (embryonic organ development), GO:0003007 (heart morphogenesis), GO:0071772 (response to BMP), GO:0048514 (blood vessel morphogenesis), GO:0060972 (left/right pattern formation), GO:0035050 (embryonic heart tube development), GO:0072359 (circulatory system development), GO:0060429 (epithelium development), GO:0002040 (sprouting angiogenesis), GO:0071363 (cellular response to growth factor stimulus), GO:0007507 (heart development), GO:0061371 (determination of heart left/right asymmetry), GO:0048570 (notochord morphogenesis), GO:0007368 (determination of left/right symmetry), GO:0030903 (notochord development), GO:0003146 (heart jogging), GO:0001947 (heart looping), GO:0007178 (transmembrane receptor protein serine/threonine kinase signaling pathway), GO:0071773 (cellular response to BMP stimulus), GO:0030509 (BMP signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0043235 (receptor complex), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:0098802 (plasma membrane signaling receptor complex), GO:0098797 (plasma membrane protein complex), GO:0005886 (plasma membrane)