Protein: Similar to PDZ-domain protein scribble (Predicted), isoform CRA_c (A6HS52)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm. Membrane; Peripheral membrane protein
InterPro domains:
- IPR055414: Disease resistance R13L4/SHOC-2-like, LRR domain (domain) [192-323]
- IPR003591: Leucine-rich repeat, typical subtype (repeat) [58-380]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [5-401]
- IPR036034: PDZ superfamily (homologous_superfamily) [702-1187]
- IPR001611: Leucine-rich repeat (repeat) [36-219]
- IPR001478: PDZ domain (domain) [712-1176]
- IPR050614: Synaptic Scaffolding LAP/MAGUK Families (family) [1-1417]
Sequence:
MLKCIPLWRCNRHVESVDKRHCSLQVVPEEIYRYSRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPVELGGLALLTDLLLSQNLLQRLPEGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLLTALPRSLGKLTKLTNLNVDRNHLEVLPPEIGGCVALSVLSLRDNRLAVLPPELAHTAELHVLDVAGNRLRSLPFALTHLNLKALWLAENQAQPMLRFQTEDDAQTGEKVLTCYLLPQQPLPSLEDPGQQSSPSESCSDAPLSRVSVIQFEDPLEGEEDAEEAAAEKRGLQRRATPHPSELKVMKRGIEERRNEAFVCKPDPSPPSPSEEERRLSAESALSGNSVPSASTASDGEPETLPAEVQGLGQQEAMPGQEEYPEEDYNEPTVHFAEDTLIPREDGEGEEGQPEAPWPLPSGRQRLIRKDTPHYKKHFKISKLPQPEAVVALLQGVQTDREGPTAGWHNGPHTPWAPRAHEEEEEEENRDEEEGEASMEEDDKEEAVASAPSVKGVSFDQANNLLIEPARIEEEELTLTIVRQTGGLGISIAGGKGSTPYKGDDEGIFISRVSEEGPAAHAGVRVGDKLLEVNGVALQDAEHHEAVEALRGAGAAVQMRVWRERMVEPENAVTITPLRPEDDYSPREWRGGGLRLPLLQPETPVPLRQRHAACLVRSEKGLGFSIAGGKGSTPYRAGDAGIFISRIAEGGAAHRAGTLQVGDRVLSINGVDMTEARHDHAVSLLTAASTTISLLLERETGGAYPPSPPPHSSSTPTATVAATMTTAIPGEPLLPRLSPSLLATALEGPYPVEEICLPRAGGPLGLSIVGGSDHSSHPFGVQDPGVFISKVLPRGLAARCGLRVGDRILAVNGQDVREATHQEAVSALLRPCLELCLLVRRDPPPPGMRELCIQKAPGEKLGISIRGGAKGHAGNPCDPTDEGIFISKVSPTGAAGRDGRLRVGLRLLEVNQQSLLGLTHAEAVQLLRSVGDTLTVLVCDGFDTSTTTALEVSPGVIANPFAAGLGHRNSLESISSIDRELSPEGPGKEKELASQTLPWEPESAETTGRNQEPLKLDYRVLAAVPSAGSLQRGPCATTGGKMTEAPSSPGSQQTKPGVIQPLAQAWPRDSPAPRGRDGPCSPPSPDELPANVKQAYRAFAAVPTVHPPENSATQPPTPGPAASPEQLSFRERQKYFELEVRVPQAEGPPKRVSLVGADDLRKMQEEEARKLQQKRAQMLREEAVTSGPDTGLASDRESLDDEQEAEQPWAGPSHAGGLSPSSPTPLGGSAPVRTAKAERRHQERLRMQSPELPAPERALSPAERRALEAEKRALWRAARMKSLEQDALRAQMVLSKSQEGRGKRGPLERLAEAPSPAPTPSPTPLEDFGLQTSTSPGRLSPDFVEELRTLDPSPSPGPQEEDGEVALVLLGRPSPGTVGPEDMTLCSSRRAMRPGRRGLGPVPS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0065008 (regulation of biological quality), GO:0051641 (cellular localization), GO:0048856 (anatomical structure development), GO:0031503 (protein-containing complex localization), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0051234 (establishment of localization), GO:0007275 (multicellular organism development), GO:0048870 (cell motility), GO:0033036 (macromolecule localization), GO:0099149 (regulation of postsynaptic neurotransmitter receptor internalization), GO:0099637 (neurotransmitter receptor transport), GO:0051049 (regulation of transport), GO:0046907 (intracellular transport), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0006810 (transport), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0060627 (regulation of vesicle-mediated transport), GO:0099072 (regulation of postsynaptic membrane neurotransmitter receptor levels), GO:0051668 (localization within membrane), GO:0051128 (regulation of cellular component organization), GO:0045184 (establishment of protein localization), GO:0097120 (receptor localization to synapse), GO:0016477 (cell migration), GO:0030100 (regulation of endocytosis), GO:0022008 (neurogenesis), GO:0098969 (neurotransmitter receptor transport to postsynaptic membrane), GO:0006886 (intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0016197 (endosomal transport), GO:0007399 (nervous system development), GO:0098876 (vesicle-mediated transport to the plasma membrane), GO:0015031 (protein transport), GO:0072594 (establishment of protein localization to organelle), GO:0008347 (glial cell migration), GO:0071702 (organic substance transport), GO:0016192 (vesicle-mediated transport), GO:0008104 (protein localization), GO:0098877 (neurotransmitter receptor transport to plasma membrane), GO:0090150 (establishment of protein localization to membrane), GO:0072657 (protein localization to membrane), GO:0048259 (regulation of receptor-mediated endocytosis), GO:0099639 (neurotransmitter receptor transport, endosome to plasma membrane), GO:0099638 (endosome to plasma membrane protein transport), GO:0033365 (protein localization to organelle), GO:1902414 (protein localization to cell junction), GO:0042063 (gliogenesis), GO:0099003 (vesicle-mediated transport in synapse), GO:0072659 (protein localization to plasma membrane), GO:0032456 (endocytic recycling), GO:1903539 (protein localization to postsynaptic membrane), GO:1990778 (protein localization to cell periphery), GO:1903540 (establishment of protein localization to postsynaptic membrane), GO:0061951 (establishment of protein localization to plasma membrane), GO:0036010 (protein localization to endosome), GO:0035418 (protein localization to synapse), GO:0002090 (regulation of receptor internalization), GO:0062237 (protein localization to postsynapse)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0098794 (postsynapse), GO:0019898 (extrinsic component of membrane), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0030054 (cell junction), GO:0045211 (postsynaptic membrane), GO:0005886 (plasma membrane), GO:0019897 (extrinsic component of plasma membrane), GO:0098590 (plasma membrane region), GO:0045202 (synapse), GO:0070161 (anchoring junction), GO:0099572 (postsynaptic specialization), GO:0097060 (synaptic membrane), GO:0099634 (postsynaptic specialization membrane), GO:0098890 (extrinsic component of postsynaptic membrane), GO:0098984 (neuron to neuron synapse), GO:0099243 (extrinsic component of synaptic membrane), GO:0005911 (cell-cell junction), GO:0014069 (postsynaptic density), GO:0098978 (glutamatergic synapse), GO:0032279 (asymmetric synapse), GO:0098892 (extrinsic component of postsynaptic specialization membrane), GO:0098839 (postsynaptic density membrane)