Protein: Pappalysin-2 isoform X2 (A0A8M3B0D2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR006558: LamG-like jellyroll fold (domain) [253-404]
- IPR024079: Metallopeptidase, catalytic domain superfamily (homologous_superfamily) [493-802]
- IPR000800: Notch domain (domain) [536-1688]
- IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [229-434]
- IPR000436: Sushi/SCR/CCP domain (domain) [1329-1578]
- IPR008754: Peptidase M43, pregnancy-associated plasma-A (domain) [648-795]
- IPR035976: Sushi/SCR/CCP superfamily (homologous_superfamily) [1394-1579]
- IPR058897: Pappalysin-1, SD scarf domain, C-terminal (domain) [849-1308]
- IPR011936: Myxococcus cysteine-rich repeat (repeat) [1079-1114]
- IPR043543: Pappalysin-1/2 (family) [1-1724]
Sequence:
MMFFRLLAIILAVFHTWPLNSAQSDHIQKYKRTLAQRAERALAGEQCGSVSRKRPPRSTAHHYPLAGVSGRYTRLTDLHLRKTHTVRSCAGDCSSSAVELTNWDANEKETFVQPQEETFIWKKEGKRAQWVTDPASAKSLNPSKRISKGLPLQTEQGADFIDSLSKTRRVARSISEFNNEEVIPEKSYNHHTEYSTENEEYSGEQEGLQSTAGELWKAEVRDVPTKWMTGIYFSGQAEQLKVNPAFAIELPRSRFTIELWVKPEGGQNNPSIIAGVFDNCSHPLSEKGWSVGIQAADPTGRKDGRFFFSLRTDRSLKSTTIIGHQRYQPDSWTHVVASYDGHKMALYVDNFKAGESSEQSGDLYSSYIKACRLFLLGGDQSDHEHSFRGHLGGVALWGYARSHEELLKSHQPHSERQSPLLSQWADFSEVENQWVPYKDRHNPVIVALPVPELQLVSPFLPPPCGVTVCDNFDIALSYNKHWQMRAEKKIRYRVVNICKDNGSDPSVSLQQIQRQHQALEDAFHPYNITLELSIHTVYNSSLQRRFILSNCHIAKVGNRHCDPECDHPLTGHDGGDCLRMGPCYNWKRRDGVCNPECNSIHYDYDDGDCCDPEVTDVAKTCFDPESPQRAYLSVKELKELLHLSSSDMLNVFFANNSAREELAGVATWPWAKEALTHQGGMILNPAYFGTKGHNNTMIHEMGHIFGLYHVFKGVSERESCDDPCQETTASMETGDLCADTAPTPKSKACHDPDPVNDTCGLTQYKNTPYNNYMSYTDDDCTNHFTPNQVARMHCYIDLVYKTWVHERKPTPVPLAPVVVGQKADSVSIHWLNPISGPLAHREGDMNCQLCDENGALHQYAHEATSPHACDSTGYWTPEEAVGAPDVYQPCEPSMQAWSPEVNLYEPNMTTPCPQSEGCVLELHFLQPVLPDSLTVWITYTSANQKAIANIVFITENGELIHTGPQHAFCDIPLTLHVHTSKKVKAIKISTFDKKLEIDAVLLTSRPQNPLCSGCRPLLYRVIREPPIREDQSPAIVRQPSYTDSDVQKDVQYLYRIQVESDGLFSELSPSLLYTHGEHFCGDATLQGTEDCDDGNLLDGDGCSKKCHVEAGFKCHGQPSLCYVFEGDGVCEEFEKGSSIQDCGFFTPQGFNDQWASTALGSHQDQRCPASRVTGEPALTQMCKSQYFDINEIVAHEAWSPCTAHYTQDQSVWLQVGFERPGVAASVIIYLAYDGSWHGENCKKTVTIELCDTNGKRHLLGSYEVSCQRNPLVVNVTHNLSVPFYQTSAVQLNFSSSQVAVVAVALRTSCHFSAFALTGCVRRLCSTESCSPVNIEHASVRCTPALDSKHCSVSCHRGFILTVLHGQSLSSHQEAELICVHGVWDRVVSCQPVDCGPPPPSHVYFASFSCPWGTTFGKQCTFSCNAPAILQGESDTLVCLEDGLWSYPEAYCKIECADPPFLPNATLLVPHCQGGGHDVGTVCRFKCNPGYYVTGTLNKKPRKKFLRLECLEGGTWQEGSCSPVTCPPLRPMFEGMYSCTNNFDFDSVCTLQCSDPTEKPSIRCTKDGRWTEDFTMCKKIVGSCQAPPEVNLVEYSCDEGFDVGAACYPTCIVPLSDPVVLANGSSADTVEHWMVPTKVQSIVCTGMLKWYPNPEQIHCIQSCEPFGGDGWCDTINNRAYCQYDGGDCCPSTLSSGKVIQFGVDCDQDECTCRDPEAGENKPKEKQQPGAP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0048583 (regulation of response to stimulus), GO:0048856 (anatomical structure development), GO:0023051 (regulation of signaling), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0050794 (regulation of cellular process), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0009790 (embryo development), GO:0009888 (tissue development), GO:0010646 (regulation of cell communication), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009966 (regulation of signal transduction), GO:0035239 (tube morphogenesis), GO:0051216 (cartilage development), GO:0048568 (embryonic organ development), GO:0048514 (blood vessel morphogenesis), GO:0001501 (skeletal system development), GO:0008593 (regulation of Notch signaling pathway), GO:0001944 (vasculature development), GO:0061448 (connective tissue development), GO:0072359 (circulatory system development), GO:0030903 (notochord development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)