Protein: Tyrosine-protein kinase (A0A8M2BAN0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR035852: Tyrosine-protein kinase Lyn, SH2 domain (domain) [105-205]
- IPR008266: Tyrosine-protein kinase, active site (active_site) [343-355]
- IPR001245: Serine-threonine/tyrosine-protein kinase, catalytic domain (domain) [227-476]
- IPR001452: SH3 domain (domain) [43-103]
- IPR050198: Non-receptor tyrosine kinases involved in cell signaling (family) [49-489]
- IPR000719: Protein kinase domain (domain) [227-481]
- IPR000980: SH2 domain (domain) [107-206]
- IPR035748: Tyrosine-protein kinase Lyn, SH3 domain (domain) [47-102]
- IPR020635: Tyrosine-protein kinase, catalytic domain (domain) [227-477]
- IPR017441: Protein kinase, ATP binding site (binding_site) [233-255]
- IPR036028: SH3-like domain superfamily (homologous_superfamily) [42-83]
- IPR036860: SH2 domain superfamily (homologous_superfamily) [75-246]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [216-480]
Sequence:
MGCKKSKLDGDQNGCVLEPVNKEHPTSQNAGLLPGQVFQKMEEKEKIVVALYPYEAIHADDLGFKKGEKLKIIEEHGEWWKARSLTTRKEGFIPSNYVAEADTMETEEWFYKDITRKDAERQLLAPANKPGSYLIRESETSKGSYSLSIRDVDAQGQDVVKHYKIRSLDNGGYYISPKITFSDISSMIKHYHKQSDGLCRKLDKACEKPKAQKPWDKDAWEISKDSIKMVKKLGAGQFGEVWMAFYNNSTKVAVKTLKPGTMSVEAFLEEANLMKTLQHDRLVRLYAVVTKTEPIYIITEYMANGSLLDFLKSQAGSKIQLPKLIDFSAQIAEGMAYIEKKNYIHRDLRAANVLVSEMLLCKIADFGLARVIEDDQYTAREGAKFPIKWTAPEAINYGSFTIKSDMWSFGVLLYEIITYGKIPYPGMSNSEVMSSVQRGYRMPRPENCPVELYEIMTTCWKNKPEDRPTFDYIQSVLDDFYTATEGQYQQQP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004713 (protein tyrosine kinase activity), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0048870 (cell motility), GO:0042221 (response to chemical), GO:0050900 (leukocyte migration), GO:0042330 (taxis), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0051716 (cellular response to stimulus), GO:0002682 (regulation of immune system process), GO:0006950 (response to stress), GO:0040012 (regulation of locomotion), GO:0097529 (myeloid leukocyte migration), GO:2000145 (regulation of cell motility), GO:0009611 (response to wounding), GO:0002685 (regulation of leukocyte migration), GO:0050920 (regulation of chemotaxis), GO:0030595 (leukocyte chemotaxis), GO:0070887 (cellular response to chemical stimulus), GO:0032101 (regulation of response to external stimulus), GO:0006935 (chemotaxis), GO:0016477 (cell migration), GO:0071621 (granulocyte chemotaxis), GO:0060326 (cell chemotaxis), GO:0097530 (granulocyte migration), GO:0002688 (regulation of leukocyte chemotaxis), GO:0030334 (regulation of cell migration), GO:1902622 (regulation of neutrophil migration), GO:0090022 (regulation of neutrophil chemotaxis), GO:0030593 (neutrophil chemotaxis), GO:0071622 (regulation of granulocyte chemotaxis), GO:1990266 (neutrophil migration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)