Protein: Xin actin-binding repeat-containing protein 1 (Q5PZ43)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Protects actin filaments from depolymerization
Subcellular location: Cell junction. Note=Colocalizes with actin stress fibers
InterPro domains:
- IPR012510: Actin-binding, Xin repeat (repeat) [104-1048]
- IPR030072: Xin actin-binding repeat-containing protein 1/2 (family) [9-1788]
Sequence:
MAEVAKQKKATEAVCGDEDFPPPPPPLPRPQVLESLQKDLSQNFLPVPPPKETFSEIYQQRQKSELKRLFKHIHPELKMTVDDVVDDELIDAINPQAADAAYQGEVQSMRWIFENWTLDNIGDPHETKKLLCEENPQGGDVKGKSSLFEHSTFDSQHAAGAERAGVVRGDVRTATWLFETQPLDSISKSKIEDEEIVEVVLKEPVQKGDVTGARRLFETKPLDSLGRCCSVEDQHFLTLKSELQENKGDVKKTVKLFQADPCCALRDSNGKIHEIKSICREEIMSSDFKTARWLFETQPLDHINEGAHVQIIRGISLEEAQRGGVDKKKWMFETQPLDAIHEGVVEEQKFQGTAVEGFSGAADVHNKLQLFENQPLSSLKGDSEGDVLEKEAIVGGNVGSTLWLFETQPMDTLKDSYEVGRLQKVMVSSDEKGEVQDKRMQFEKSTAGKTAGDSGNKVQNDEKGDVKTFKSLFETLPLNVSEKAQSQIHDITSGDVKGHCSLFETTPLYAIKDCAGKFHEVTTVSREECIKGNVQNYKWMFETRPLDQFEEGSGKVELIKGITRQEDMTDDTRTAKWMFETQPLDCMSLNSRTDVDSTQKEFKKSNVKTCKWLFETKPMDMLYEKSEGKQDVEPVPKADVKSHTWLFETQPLDNIKDKENLGLKLCSTVQEDVKSDVNVKTVKHLFETEPLDRITDQADSGQNVRCVSQVDMQSGDVSRVKEIFESKSLGTESSKWSEEQKNEIQSGSVHKFTWLFENQPIGDINEKEERIVSCDVEAGDVGGKKFIFETLSLDKIKDKDELLEHPSMIIEKPLSSSVNVKSNTMLFESQPLYAIRDKDGQFHEVTTVMKEEVMRGDVRGARWMFETKPLDTIQADKEIYVIRAVTQEDVHKGDVKSARWKFETQPLDSFTPHEGPSVRVVEDIGNEKCVQQSRQLFETEQASQKKFVRMVSVTDVQQGDVRTSTWLFENQPIDTLKGEPDEQNNLTAVHREDNTKGDVKRCTWLFESQSLDKIKDNKPTEELVSSREEIPKADVKSTTWLFETTPLDKITVESVTDILYRLCHNSFIHSSGIIIQANDYKYVNMAKYQIMKDEGPKVLKEEVVEGNIRNLMLQLLFKPNIKPMVVLLKEDEQGKMHSTVLEIPFQQPGSATNPEAECKTQEAVKIIENLLVQQKEIKTGLVMQESEGGQPEMTVYSLHCESSLTESQTITRGDVKSTIGNLLATVHSQQTKQSCRMEEIERGNVNLYKSCIEKGDLKSLQRELSEEDLVTSCRDQIEIVQGDVKEAMRHLSQQREQVERTILDVVPGDVKNVKKVFSDVCTDLSIGNCVPREEIVRGDILSAKQQLGEAVKQQVMVQKEEIVSGDIKATLESLERAKQQSMQVEREVIKPGTIYDLNVEAEEMCSEENESKLVKEEIIPGDIKAAKRSLERAKNQSMKVEREPITPGKLYNLNETSQCQSSTTVEQSTTSTYSNHRITTTFRKVSDIEKDQESIKRLCCLNEVGGGGKNIYINTEDALRMVDISESVPDVVKGDVKATIQSLRSASTEQRSVDREEIVRGNMQETLQCLKKSSINISRGDYKAAMLYKQSGQPYTQSKITNDSGTKDCKQSFDHIPSSHTQLSSSVSVTRSEHPTSLALNSESVSSNADNSKNSSAFTGKDEHPPPILPKTGHQVKDQKPVIPPKPLHITTSSPPLFTETSNMCPNSTVSINDTQQTPAIPLKVTPSNKMFTHETEIAKTSNKIKDKESKIHEQVQRTNLTDPTDFQRMQYTEQWVQNSHMQITDTPSVNKTDSFKNGSFPGDSIGMEKNVVQRINAAEEIRMCYSKDNDELNKGFKAVLQNFGEKKTTTDTGSPFPKKIKVVQKENIQEQAKTSNKDELHFTSRDTSSTPNKHEVPSIHNNSENKVVLREKKAKRETEDERRQRLSIHRDEIMRGNVKAAMEIFENLMRREELKVILSKVQEIEGETFEVDVRSLKTLFENVPAWITNPKENTKRRHRPRVAKETEGLRDDLESISSVEAAFEDLEKASMDIVNLKEQTLAKLLDIEEAIKKALYSVSNLKSEADIAGLSGLFSESLSPDNVSPSTKNIRKISIVSSKTKPAQSNQMQSADNRALYKEVPHVPQVQVSKQSSNVPSSPSFISIHSAARKPAESPTDKPKTNADQSNAGSSSSQNSSASHICSPPSPRRKVSVLEVQRVPEVPSGIFGTKTVSEKYEETDCFGNTYYSSKRSTFVTRQSETELSSSYDVVTSPRRSEGMTSPVLQRSGQSFSSNSLSKGKDRKVFVTFGHPNTEKH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0042805 (actinin binding), GO:0051393 (alpha-actinin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0071840 (cellular component organization or biogenesis), GO:0061061 (muscle structure development), GO:0009887 (animal organ morphogenesis), GO:0048729 (tissue morphogenesis), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0003279 (cardiac septum development), GO:0016043 (cellular component organization), GO:0003205 (cardiac chamber development), GO:0003281 (ventricular septum development), GO:0003007 (heart morphogenesis), GO:0060415 (muscle tissue morphogenesis), GO:0072359 (circulatory system development), GO:0060537 (muscle tissue development), GO:0048644 (muscle organ morphogenesis), GO:0003231 (cardiac ventricle development), GO:0007517 (muscle organ development), GO:0034330 (cell junction organization), GO:0007507 (heart development), GO:0014706 (striated muscle tissue development), GO:0048738 (cardiac muscle tissue development), GO:0055008 (cardiac muscle tissue morphogenesis), GO:0045216 (cell-cell junction organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction), GO:0070161 (anchoring junction), GO:0005911 (cell-cell junction), GO:0044291 (cell-cell contact zone), GO:0005912 (adherens junction), GO:0014704 (intercalated disc)