Protein: RING-type E3 ubiquitin transferase (A0A1D8PT95)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein
InterPro domains:
- IPR058051: Synoviolin-like, RING finger (domain) [386-444]
- IPR050731: HRD1 family E3 ubiquitin-protein ligases (family) [4-529]
- IPR024766: Zinc finger, RING-H2-type (domain) [388-444]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [362-455]
- IPR057992: E3 ubiquitin-protein ligase synoviolin-like, TPR repeats (domain) [11-367]
- IPR001841: Zinc finger, RING-type (domain) [389-444]
Sequence:
MLINKTQQYIIGYSSISIALLSWSIYDSLRKSFNFVMFLVEFTDGIKLGIIVNFIIFLFLIIDKSLQILLFGSLRMIEVEHLFEKLPIFVINLLLNLATGDNNIIMNVFLMGLSMSFKVFHVIMFDRLDYVNLIIVNKINDEDIYLNQVIYHFGTSINFWLNIFFIFADFSLAKFLVYDVFQGINSVTCLLFGFQFAVQGVQALTYFSKLLLGIYEIAFYRIRKNEHHTSLRGWQESTTTSANLEETERTTNNNDNESGQVEVEVEANIDEDVDVDADADADVDVEEEIVNDEDDDIELIWDNKPYYTKGIDIASAVLTSISYLSFVYLLTIHSGLSLPLSMLQGTYSSMRRAWVETNQLLAFIESSKRLDTQLANASAEDLSQSDSLCIICREDMHSVEDYQRIFKKPQSPRRSPKKLKCGHILHLGCLKEWLERSDSCPLCRRKVFSNDGATNATNNNNNNNGENNQNNGNVPPPQPGDVPVPPPAPTATATATAAAVNAELQREVREINDLLQNAENTIAPQEQPINTAAEPIEGPSRTIPLPSSSSTLPIPQSNDLSQSITLPKNALLPPGWLVIPLKKPEQENSDIDYKVNISSYHQADLKINNKKPSTRDIITYAIPKEESIGEYEM
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity), GO:0061659 (ubiquitin-like protein ligase activity), GO:0061630 (ubiquitin protein ligase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009628 (response to abiotic stimulus), GO:0042221 (response to chemical), GO:0006807 (nitrogen compound metabolic process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0009408 (response to heat), GO:0009266 (response to temperature stimulus), GO:1901564 (organonitrogen compound metabolic process), GO:1901698 (response to nitrogen compound), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0019538 (protein metabolic process), GO:0035966 (response to topologically incorrect protein), GO:1901575 (organic substance catabolic process), GO:0043170 (macromolecule metabolic process), GO:0010033 (response to organic substance), GO:0034976 (response to endoplasmic reticulum stress), GO:0009057 (macromolecule catabolic process), GO:0035967 (cellular response to topologically incorrect protein), GO:0010243 (response to organonitrogen compound), GO:1901565 (organonitrogen compound catabolic process), GO:0006508 (proteolysis), GO:0051788 (response to misfolded protein), GO:0071310 (cellular response to organic substance), GO:0030163 (protein catabolic process), GO:0010286 (heat acclimation), GO:0034605 (cellular response to heat), GO:0071218 (cellular response to misfolded protein), GO:0070370 (cellular heat acclimation), GO:0036503 (ERAD pathway), GO:0010498 (proteasomal protein catabolic process), GO:0051603 (proteolysis involved in protein catabolic process), GO:0071712 (ER-associated misfolded protein catabolic process), GO:0006515 (protein quality control for misfolded or incompletely synthesized proteins)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)