Protein: Interleukin-8 isoform X2 (A0A8M3B7M3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted
InterPro domains:
- IPR039809: Chemokine beta/gamma/delta (family) [8-92]
- IPR001811: Chemokine interleukin-8-like domain (domain) [31-92]
- IPR033899: CXC Chemokine domain (domain) [33-93]
- IPR001089: CXC chemokine (family) [33-89]
- IPR036048: Chemokine interleukin-8-like superfamily (homologous_superfamily) [17-92]
Sequence:
MTSKIISVCVIVFLAFLTIIEGMSLRGLAVDPRCRCIETESRRIGKHIKSVELFPPSPHCKDLEIIATLMTTGQEICLDPSAPWVKKIIDRIIVKKP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (signaling receptor activator activity), GO:0005126 (cytokine receptor binding), GO:0048018 (receptor ligand activity), GO:0001664 (G protein-coupled receptor binding), GO:0005125 (cytokine activity), GO:0042379 (chemokine receptor binding), GO:0008009 (chemokine activity)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0002376 (immune system process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0009605 (response to external stimulus), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0042221 (response to chemical), GO:0042330 (taxis), GO:0002682 (regulation of immune system process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0050900 (leukocyte migration), GO:0009607 (response to biotic stimulus), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0048523 (negative regulation of cellular process), GO:0051707 (response to other organism), GO:0007154 (cell communication), GO:0097529 (myeloid leukocyte migration), GO:0043207 (response to external biotic stimulus), GO:0009611 (response to wounding), GO:0048468 (cell development), GO:0001568 (blood vessel development), GO:0030154 (cell differentiation), GO:0080134 (regulation of response to stress), GO:0048731 (system development), GO:0030155 (regulation of cell adhesion), GO:0006952 (defense response), GO:0032101 (regulation of response to external stimulus), GO:1901700 (response to oxygen-containing compound), GO:0071216 (cellular response to biotic stimulus), GO:0010033 (response to organic substance), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0000902 (cell morphogenesis), GO:0009991 (response to extracellular stimulus), GO:0002523 (leukocyte migration involved in inflammatory response), GO:0007584 (response to nutrient), GO:1901698 (response to nitrogen compound), GO:0007162 (negative regulation of cell adhesion), GO:0030595 (leukocyte chemotaxis), GO:0070887 (cellular response to chemical stimulus), GO:0002697 (regulation of immune effector process), GO:0009617 (response to bacterium), GO:0031668 (cellular response to extracellular stimulus), GO:0006935 (chemotaxis), GO:0071496 (cellular response to external stimulus), GO:0016477 (cell migration), GO:0035239 (tube morphogenesis), GO:0071621 (granulocyte chemotaxis), GO:0031347 (regulation of defense response), GO:0030097 (hemopoiesis), GO:0097530 (granulocyte migration), GO:0071219 (cellular response to molecule of bacterial origin), GO:0071310 (cellular response to organic substance), GO:0001944 (vasculature development), GO:0022407 (regulation of cell-cell adhesion), GO:0002237 (response to molecule of bacterial origin), GO:0033273 (response to vitamin), GO:0033280 (response to vitamin D), GO:0060326 (cell chemotaxis), GO:0048863 (stem cell differentiation), GO:0000904 (cell morphogenesis involved in differentiation), GO:0006954 (inflammatory response), GO:0050727 (regulation of inflammatory response), GO:0048514 (blood vessel morphogenesis), GO:0033993 (response to lipid), GO:0031667 (response to nutrient levels), GO:0072359 (circulatory system development), GO:0001570 (vasculogenesis), GO:0031670 (cellular response to nutrient), GO:0014070 (response to organic cyclic compound), GO:0002244 (hematopoietic progenitor cell differentiation), GO:0022408 (negative regulation of cell-cell adhesion), GO:1901701 (cellular response to oxygen-containing compound), GO:0031669 (cellular response to nutrient levels), GO:0071305 (cellular response to vitamin D), GO:0030593 (neutrophil chemotaxis), GO:0060218 (hematopoietic stem cell differentiation), GO:0060232 (delamination), GO:1990266 (neutrophil migration), GO:0071407 (cellular response to organic cyclic compound), GO:0071396 (cellular response to lipid), GO:0071295 (cellular response to vitamin)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)