Protein: Fe2OG dioxygenase domain-containing protein (Q9W232)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm. Nucleus
InterPro domains:
- IPR037151: Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily (homologous_superfamily) [124-330]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [25-118]
- IPR029063: S-adenosyl-L-methionine-dependent methyltransferase superfamily (homologous_superfamily) [357-614]
- IPR005123: Oxoglutarate/iron-dependent dioxygenase domain (domain) [220-325]
- IPR051422: AlkB Family tRNA Methyltransferase/Dioxygenase (family) [356-609]
- IPR034256: ALKBH8, RNA recognition motif (domain) [40-119]
- IPR013216: Methyltransferase type 11 (domain) [400-489]
- IPR027450: Alpha-ketoglutarate-dependent dioxygenase AlkB-like (domain) [137-322]
- IPR035979: RNA-binding domain superfamily (homologous_superfamily) [29-112]
Sequence:
MHVEETQQKVNKAKKADKKQRRCLAIIKSDCEVSPSAEPTPYLAVLNVGLSNGLTEECLLTEAAATGGKVIQVVMLPGKSYCFFICASLEDSQLIYEGMHNISTIGQQGAVAYLSYIRQLPALAGKSEWNKPLPRGLHIIADFVTEEEESTLLRAIGEDGRTSEVTGSLKHRNVKHFGFEFLYGTNNVDPSKPLEQSIPSACDILWPRLNSFASTWDWSSPDQLTVNEYEPGHGIPPHVDTHSAFLDPILSLSLQSDVVMDFRRGDDQVQVRLPRRSLLIMSGEARYDWTHGIRPKHIDVVPSASGGLTTQARGKRTSLTFRRLRKGPCDCSYPALCDTQQTKVPQELHASLAAQAITLEQQNVHEVYDKIADHFSETRHTPWPQVSEFLDSFEPQSVVLDIGCGNGKYLSCNPLLLSVGCDRAQGLLAVGRRKGQNVFRCDCLVVPVRSSSIDGCISIAVIHHLATKERRLAALQEMARVLRPGGRALVYVWAKDQRKNDKKSTYLRQNKAVNKERTTEQQQRQKQHQELEQQLSNNNPLPVHTNRTEFQQQDVLVPWKTKDEQKTTYLRYYHVFEEQELENLVSQVHEVQLIKSYYDQGNHCAIFEKLSNNSL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016740 (transferase activity), GO:0140098 (catalytic activity, acting on RNA), GO:0016741 (transferase activity, transferring one-carbon groups), GO:0008173 (RNA methyltransferase activity), GO:0008168 (methyltransferase activity), GO:0140101 (catalytic activity, acting on a tRNA), GO:0008175 (tRNA methyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0032259 (methylation), GO:0006807 (nitrogen compound metabolic process), GO:0051716 (cellular response to stimulus), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0070887 (cellular response to chemical stimulus), GO:0043414 (macromolecule methylation), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0043412 (macromolecule modification), GO:0090304 (nucleic acid metabolic process), GO:0001510 (RNA methylation), GO:0010467 (gene expression), GO:0030488 (tRNA methylation), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0009451 (RNA modification), GO:0034470 (ncRNA processing), GO:0006400 (tRNA modification), GO:0034660 (ncRNA metabolic process), GO:0002097 (tRNA wobble base modification), GO:0006399 (tRNA metabolic process), GO:0008033 (tRNA processing), GO:0002098 (tRNA wobble uridine modification)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)