Protein: Zinc finger FYVE domain-containing protein 26 (A0A8M9QF82)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Phosphatidylinositol 3-phosphate-binding protein required for the abcission step in cytokinesis: recruited to the midbody during cytokinesis and acts as a regulator of abcission. May also be required for efficient homologous recombination DNA double-strand break repair
InterPro domains:
Sequence:
MHPFGREEETSRRELFGFFRRCLQRGEWELAAACVSQLGEARAEDPHSPRDIVKAIVTHPYPLRWETVGSPHRLAWYWLQVLERPTEIKVSVSVKRELEFLLLLEELEDIPQSVLKELHEAFLYSEEVKGKAPGDSASPLSAALLSCLRSLLTRQQPRLCHSLISFLSNGDPSRDHTLQDAFIQHLTEQVKVPAKDRNREWVEQVCSVLALAPWGSDRSGAQLEPLWEGLWAAREGLMTEERILGCLLRPQSQALLMAYSSTALRLLKDKLLAEAPHTQVDLPDLERVMLGLCCHKDKRLAWKAIYFECLSSGKHFLEQVLLTGLDLIKREEFSKLETLLHSEFQPLSRLLLLLGWMHCQSLESAKTLLTVLHHRQPQSNDSALSDLACTLSCQLGVLEWCTQNNPGISHDALLSHLHMLDHHSALYVLHCLTPLAKFEEHKVLELLQRTGDPSQVDSPSSSVQRNITLFRGFCAMKYALYAISVNARTHAHTGSLDCEPLHELQTEAAQEDETAEGCSNLFQHYLSECQLYLEAVPALFRLELLENIFSLLFLSDSDFTQQTSTATETQPYTNTETSKPKSTKEVNTAEHFLKAENEGERMDELNQINPQLGHLTSGCRGFLVDLNVMEGILRLVREGLEGVCGVGQEDGRALGADVELAESLGCSVTAETFSARLQRLSKYTAEAQWRLQIVTSNHGNGNDGLYLPSPLPSPALPLKRQGSGSSGTSSRRRRKHHRHRSERHVSSERQNGEVSTSTSDGGVCVSVVCRGTETCPCGGSHSWLVPAMLSPPESLLIACIRRGNYIEAQQVIAMYGLENSECAGELVFMDRYREVLIELAQVEQKIESQSLSTSSSSSEGLGTLGATPAGRTRMGSSSRLTLKSIGSAAAAGMAFYSISDVADRLMSTPSRPIPCLEDSYWLSQCTIDSPDFVRPLVEELSPAAMAAFDLSCCQCQLWKTSRQLLETAERRLSSFLEARGVRVDPKVPHANGIRGFPSVLQQISKILNKTSTNKGMSKTDCNGEENAVCSPFGCSAQEVLLSCHSTLTEESITIQQNLNQRLEVTLQTLSSATNTSVDSLVGSNLLTALAEQAALKQSELDCHPVRTAMKQLLQYLDQLCPLVPDGAPDRPDYIRSFFDYVNVLASVLVRSLGSEDQSTVVKLGNPLLLLLQSPAQLLSHLLFDRQVSPDRVLSLLQQERLRLSVQQVVVQRCCETLPLWDSRAVNFSQRVSGLNGGAFCPASIASILQQYAQDCSPSLDLSDPTTTSDPSSESEVSVEDVSAASTSLSTSPPSPSSSSPSSSFLLTPSALSFLKSRSPLVAALACLSASRGGVTRVTSSGWSGLPSYFRGSGRKEAVLDGEQISREGEALLKNFPILRMYLRTMAEPVLGVSLEADEGLGVALCGKPVVGMLFSGLQGNAAQAMAAEAFQQALNNGDLNRALDLLELYAQPCSQEGALRDKLLAFTALQESSSAEQLFRVRDWELRGRVVLQGLDRWPLQQCLDLLHFCLSDQNTKDPLREQLQQRKQELDMYQRMLRLQPSLPWETWQELREESTKNPESVFSQMLEAREFELCAQWVQLYSVSDQSGMQLQTEHLLYLLEHNHTEEAFQLLEALSDSMGLEVSERALDRRPGLAACHFLSDYLTLHFQSQMTPARRRHIHALHLGSKVLLTLPEASRQDYFSLLSDPLLMLEQMLMNLKVDWAAVAITTLRSLLLAQDAGITTQHIDTLLADYARKALDFPYAPREWSRSDSVISLQDAFLQCPAQESCPSSPSHTPPPSTGGTPMQTPSSERRPSGKKIRPLATPFTPPEKTPDRKDWIPDHKQHICMVCQRERFTMFNRRHHCRRCGRLVCHSCSSKKMAVAGFDEPVRVCDQCYNFFHTDSDEELEQGEVAGSPSSIDEVLNGVLSLPEVSRKQYRLSPNPAENQQLKSEFYYEQAPSASLCVAILTLHSDHAACGQQLIDHCRSLSRKLTNPEVDARLLTDVMRQLLFSAKLMFVNAGCTQEPALCDSYISKVDVLKILVTANYKYIPSLDDIQETAAVTRLRNQLLELEYYQLAVEVSTKSALDPNGVWQAWAMASLKAGNLSGAREKFVRCLKAPVDRNQLNHGPRLLQEIIQHLESTVKLTLSQTMDEDILASLRELEEALSDSAPPEGTESKVQRCNFHQECLFYLFTYGTHLSLISFYLRHDCLKDALTYLQNKGCSDDVFLEGIFQPCLERGRLGALQGLLENLDPTLETWGRYLLSACQLLQRRGHYHSLYQLQQFMMDHIRAAMTCIRFFSHGAQSYLQLGEQQRWLIRAKEHLRTYLQEQQSRRKSHSSSFRKKMSSTDVSRHIHTIELQLEVTRFLHRCESSPSKTAVGSTYTGNSAPPTLFGNSPMKVDVACKCLTVMLGGKNIEEGFGIAYRVIQDFQLEALAVYIRVGQRLVRQRQYSSVRQLHKCVGESGTASKHDCDAIVLSCVSVADKSPADAKELETLILECKNPENKIKAYLQCSKLRAAYLQAVKLKLVKATPLIQEVMRAAESSGDSVMHDICRQWLSEHQEPSSKQR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0008289 (lipid binding)
Biological Process (BP): GO:0008150 (biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0071840 (cellular component organization or biogenesis), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0032989 (cellular component morphogenesis), GO:0000902 (cell morphogenesis), GO:0007276 (gamete generation), GO:0007281 (germ cell development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0016043 (cellular component organization), GO:0009994 (oocyte differentiation), GO:0022008 (neurogenesis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0007292 (female gamete generation), GO:0048599 (oocyte development), GO:0032990 (cell part morphogenesis), GO:0048477 (oogenesis), GO:0048858 (cell projection morphogenesis), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0048812 (neuron projection morphogenesis), GO:0061564 (axon development), GO:0007409 (axonogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0033643 (host cell part), GO:0043657 (host cell), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0030430 (host cell cytoplasm)