lokahq/bioreason-rl huggingface dataset:
Protein: Interleukin 4 receptor, tandem duplicate 1 isoform X1 (A0A8M2BBP4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
Sequence:
MKFNVSFANREAASRLKFPHFELVVWTFCVRQRSKLSFLCFTSRTRKPIGYRMSSSLFLYQIILTLVCQALCDDPIKDFNCFNDYEAEMTCSFSSESLRNCSGYNMNVTQKLAYEINRYSCVFERSHHNAICECKIEVEGFITEEIFSTTLLKGTKVLLQRDFKTIDYIKPKTPVLFVKKTENGNFHVTWVDSYEQRNVFTDNLFITLTYRIKGEIETNSTKVANTVGFCDIVGSLLQPKTEYILTAKMSSNYNGQKIYSDQSAAVHFTTAPLPNEIVKLVVPPLCIGLLIIICMTFICFLRMKSNWWDKIAKPTIKDNFGNKKGQVLPPSSNAVYPNQVEVINLDFEEEKKSISPVCVNPNNERSSHSVESSPGDYGQAVCDSGSNPVQDIRSQLEFAIAQDNLRLKWNTPLNQFTEMPYNSVESSSKERNRANRDSGTCSGSSVFSNKSYLEGTTDDSSFLDLNCDHSDDRKVSDSIFKLENSIDIIKSLQNFPDEGYQAFSAVVEKRDVVDGCAKLSSNVDADDNVIRQNLITSANPLYSPLLHHDHTIARDDPYKAFQDVSKNTGGQWSTSISTERTLNECGALKFPHIAGQTALLQNTAWDFLNIPPTVEIDLSYHAV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:0009607 (response to biotic stimulus), GO:0006955 (immune response), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0051707 (response to other organism), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0043207 (response to external biotic stimulus), GO:0070887 (cellular response to chemical stimulus), GO:0006952 (defense response), GO:0007166 (cell surface receptor signaling pathway), GO:0009615 (response to virus), GO:0010033 (response to organic substance), GO:0045087 (innate immune response), GO:0098542 (defense response to other organism), GO:0034097 (response to cytokine), GO:0140546 (defense response to symbiont), GO:0051607 (defense response to virus), GO:0071310 (cellular response to organic substance), GO:0097696 (receptor signaling pathway via STAT), GO:0034340 (response to type I interferon), GO:0019221 (cytokine-mediated signaling pathway), GO:0071357 (cellular response to type I interferon), GO:0140888 (interferon-mediated signaling pathway), GO:0007259 (receptor signaling pathway via JAK-STAT), GO:0071345 (cellular response to cytokine stimulus), GO:0060337 (type I interferon-mediated signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Thrombopoietin isoform X1 (A0A8M6Z2C6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted
InterPro domains:
- IPR001323: Erythropoietin/thrombopoietin (family) [43-188]
- IPR009079: Four-helical cytokine-like, core (homologous_superfamily) [38-192]
- IPR003978: Thrombopoietin (family) [15-192]
Sequence:
MESNVTGDFMLSLGMDLNRVLVVVFSMVVSELSHVHTRPIDFVCDSEARRVMNKVKDLQEEKVICSGVDALPSSIQLPCISIHKATWERKSVQERRAEILLSLGTLAQDVRSARTLSQPGCGLTLLKRLEHSINNYLYVVRLLHVEQGEQEGPAVERCLGQPSKDLGLVLKYFGLLLTGKLELLIAEMAKWC
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (signaling receptor activator activity), GO:0005126 (cytokine receptor binding), GO:0048018 (receptor ligand activity), GO:0005125 (cytokine activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0008283 (cell population proliferation), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0030154 (cell differentiation), GO:0048468 (cell development), GO:0030097 (hemopoiesis), GO:0030099 (myeloid cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure), GO:0048471 (perinuclear region of cytoplasm)
Protein: LIM domain-binding protein 2 isoform X1 (A0A8M2B3G5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR029005: LIM-domain binding protein/SEUSS (family) [30-346]
- IPR041363: LIM interaction domain (domain) [312-351]
Sequence:
MSNPPHDPFYSSPFGPFYRRHSPYMVQPEYRIYEMNKRLQSRTEESDSLWWDAFATEFFEEDATLTLSFCLEDGPKRYTIGRTLIPRYFSTVFEGGVTDLYYILKHSKESFHNSCITVDCDQCTMVTQHGKPMFTKVCTEGRLILEFAFDDLMRIKTWHFNIRQYRELIPRSILAMHAQDPGVLEQLSKNITRMGLTNFTLNYLRLCVILEPMQELMSRHKTYNLSPRDCLKTCLFQKWQRMVAPPAGHPQNFKTEIFPTNHKKEPTRQTTTKRRKRKNSASSASNSSLGNSAGGKKRSPANNFSLASQVPDVMVVGEPTLMGGEFGDEDERLITRLENTQYDATNGLDDDDDFTSSPALANNSPWNSKPPTGQDSKPESTASQPSQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0048519 (negative regulation of biological process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0023057 (negative regulation of signaling), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0090287 (regulation of cellular response to growth factor stimulus), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0001568 (blood vessel development), GO:0010646 (regulation of cell communication), GO:0048731 (system development), GO:0009966 (regulation of signal transduction), GO:0090288 (negative regulation of cellular response to growth factor stimulus), GO:0035239 (tube morphogenesis), GO:0030514 (negative regulation of BMP signaling pathway), GO:0048514 (blood vessel morphogenesis), GO:0090101 (negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway), GO:0001944 (vasculature development), GO:0072359 (circulatory system development), GO:0090092 (regulation of transmembrane receptor protein serine/threonine kinase signaling pathway), GO:0030510 (regulation of BMP signaling pathway), GO:0002040 (sprouting angiogenesis), GO:0032925 (regulation of activin receptor signaling pathway), GO:0032926 (negative regulation of activin receptor signaling pathway), GO:1900107 (regulation of nodal signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: NHS-like protein 1 isoform X7 (A0A8M1RP42)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR024845: Actin remodeling regulator NHS-like (family) [20-1490]
Sequence:
MVFIGTSLKTVIKYFKRKAVSNLDEEKKWTVHYTAPWHQQENVFLPGSRPACVEDLHRQAKVNLKTALRECDKLRKDGFRSSQYYSQGPTFSGSSSSQHEDEDLEGDDADKKSTASSGEEEKDSCQMRAQSPAQVEGVEVDGQMSSSKASVLPTPEEKMRQQAQAVLTDIVPINVTGETFDRQASIRRSLINTDTLVRRPKKVKRRKTISGVPDSVQQELAAKGRGGELRPQSMFIPGQYSTLGRVMNGNSTLRQSVTKDSGCQTEAVKIVPPSVRRIRAQKGQGIAAQMAGISTSATNISSVSDGSSTGGSIVAMAPQFGNDIQRFHSLPRGARVSLNAEPIYSSTPFRKEDSCAKAPKQIGKLQVDNTAVHMRNAPRVCTQARPKSQEVRGSQREWGSVSGPACVVSPHAAYSTSLIPNATLSCSAEVFALHSKSSPGQSPLSGSPYTKARPLSMVSVVNSGSTSSVGTGSHTPDAGMKDTCSETGQSDSSLHSHSTIAAGTLSSDEQWIYDTPDNALPRRTMTSSCSTPINHLYSSLERSSKGTDSSSLYSMDNDGYYTSMHLDSGLRSRSHGSGHGHGIGGRAVRHSMYECLGEQEDRNSLCSDHSLSRSISLRKPKKPPLPPARTDSLRRKPGKNSSPSANIGQSNIRNGSLLNESLIATLQQSLQNGLKGKGSSTSPSHSPCSDYEDPWMLRPRSQSSISASSSGVSATGMAHVYSICPVTPSHSDTSSLRSDYADSWGYYMEYPRPSGDQTQSPCTNSHSAGQVSEMANGRGPLNGNQANLPAVQEGSDMSAKPRTGTSSPDRVHRLTSPSSGYSSQSNTPTAGTPVPSFMRCMSPSGKPKPRVPERKSSLLSSVSISSSSTSLSSNTSDSNRSNIPPPPPLPAAPVVLVPLNPPSFPPPLPPPSPVCTEDQKFPPPPPPLPTTPHQQASMNPLQNNSSPEFPPPPPPEVLTDPACSGFNSSFSPPPPPPPPPLPTYSPSQNQHLPHMTPQTPSSASLKEIKGCLKPVNLEGRPVLPQSEEPNKVSMPLITPFALQSVQLRPAKRPENNEVSRTDRPQTPEKTHPTVPQISCISPNVSLSSTEEKPSIQHSQDGLVEAQTDYSVKSNSDPTSFLTNGPIDLGEATDEVDGLKTFLSTQVEKSLNSTPKKKPPMISKKPKFSLTFSSVDHVRDFVSAEVLDPIPVLEKEEETTEKSSFDISVPPVEIRDISPTNGESQEFSQSSGTTILDVDKSTSEAEDEEERDDEDVTSSTGSFSSKDDENGDVFESSTLDVAQSPSINGDSCGDMVTPTRPRTTEDLFAAIHRSKRKVLGRKESEEDRSRGPLSPPVTPTAQSPSLTSSLPRQSGSIQRSLRKSATSSDTFKALLLKKGSRSESSFRMSATEMLRSTDPRFQRTRSLDSSFDPASPTSESPCSSPGRSKRVADDWARNDGMFSTSPSLIGPKYGRSRTPPSAASSKYNARCRILSSPMTVICERDGELTDCEDPVSPSNTPLPISQDSNSTLCEQSSS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0046983 (protein dimerization activity), GO:0046982 (protein heterodimerization activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048870 (cell motility), GO:0030154 (cell differentiation), GO:0016477 (cell migration), GO:0048731 (system development), GO:0001764 (neuron migration), GO:0022008 (neurogenesis), GO:0007399 (nervous system development), GO:0048699 (generation of neurons)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Gephyrin isoform X4 (A0A8M9P8X5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR036688: MoeA, C-terminal, domain IV superfamily (homologous_superfamily) [804-886]
- IPR038987: Molybdopterin biosynthesis protein MoeA-like (family) [415-886]
- IPR005111: MoeA, C-terminal, domain IV (domain) [808-882]
- IPR005110: MoeA, N-terminal and linker domain (domain) [497-639]
- IPR001453: MoaB/Mog domain (domain) [15-795]
- IPR036135: MoeA, N-terminal and linker domain superfamily (homologous_superfamily) [497-646]
- IPR036425: MoaB/Mog-like domain superfamily (homologous_superfamily) [1-801]
- IPR008284: Molybdenum cofactor biosynthesis, conserved site (conserved_site) [81-760]
Sequence:
MASDGMILTNHDHQIRVGILTVSDSCFRNLAEDRSGINLKDLVHDPSLLGGIISAYKIVPDEIDEIKEILVDWCDEKELNLILTTGGTGFAPRDVTPEATREVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDALEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEDEEKKDSGVASTEDSGSSHITAAAIAAKSMTSHLSHAVVMAKGGQPLSGFIPSTSIPSHFTCSCSDTIPESIISRGVQVLPRDTASLSTTPSESPCAQQSRLSTASCPTPKARLTSCSSTYSVTEASRREFRAHLDDVISHKSRYSTLDQLHSRLEGLKDDRRNHRTFDSRVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYRGPYTGDLAPLPRKGIWRQNGSSWRKIPLCTGAEAKAERRALANAAHTPKYCTDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTLTVMPGQVMRVTTGAPIPCGADAVVQVEDTELLRESEDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVQKFPVVAVMSTGNELLNPEDDLHPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGARKLIFALPGNPVSAVVTCNLFVIPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016661 (oxidoreductase activity, acting on other nitrogenous compounds as donors), GO:0008940 (nitrate reductase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051641 (cellular localization), GO:0071840 (cellular component organization or biogenesis), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0016043 (cellular component organization), GO:0051668 (localization within membrane), GO:0008104 (protein localization), GO:0099173 (postsynapse organization), GO:0034330 (cell junction organization), GO:0061024 (membrane organization), GO:0072657 (protein localization to membrane), GO:0001941 (postsynaptic membrane organization), GO:0050808 (synapse organization), GO:0043113 (receptor clustering), GO:0072578 (neurotransmitter-gated ion channel clustering)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: PHD finger protein 21A isoform X1 (A0A8M9PN21)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR019786: Zinc finger, PHD-type, conserved site (conserved_site) [560-601]
- IPR019787: Zinc finger, PHD-finger (domain) [557-604]
- IPR001965: Zinc finger, PHD-type (domain) [559-602]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [549-604]
- IPR011011: Zinc finger, FYVE/PHD-type (homologous_superfamily) [546-614]
Sequence:
MNVCNTASVSPTVTWRGCSSESSDGRANDPAHLLHCHKFLSSGPLLFSDRLKVSRDSLFWRTGSMMELQTLQEALKVEIQVHQKLVAQMKQDPQNADLKKQLHELQAKITALSEKQKKVVEQLRKELLVKQEPDLKPQTFAATTDGKTVLLTAACPASQPISGPPHNQGAPQKTLTVTPVITAKTLPLVLKAATSTMPASMATQRSAVAMVTAINNPTRPGANSDSQSTPINLQMASKLPNQDTDAGTRIVSKNVIVVQATTTSAQPIKVPQFVPPPRLTPRPTFQPQVRPKPPTPINVPIAPAPPPPMVAAPLIQRPLMLTTKLTSSLPASAGPIHQVRIVNGQQCTTIDKTTTTVTGTTQLAGIVISPAQTLQISNLNSDLKTVKPQGGPEQVVIKTPPSSSPPLPPPPAKVKREESPQKLAFMVSLGLVTHDHLEEIQSRRQERKRRTTANPVYSGAVFEPERKKSAVTYLNTPLHQGTRKRGRPPKYSTTTTTTTSSSTAVPELGCNPLLSPTSSLPASPAPERPDTGGFPLSVHPHSVPQPSPSSGDGDIHEDFCTVCRRSGQLLMCDTCSRVYHLDCLDPPLKNIPKGMWICPKCQDQILKKEEAIPWPGTLAIVHSYIAYKEAKEEEKQKLMKWSAELKLEREQLEQRVKQLSNSITKCMETKNSILARQKDMQASLEKVKHLVRLIQSFNFTQPMETETLKDSKQDCAESGSIKDSKDTTQVCVQESPTEPSVQVPAAVAVPEVKAEPEVGEMAEPAAAVTPEAVSGESGVSVLEVPKTTVDEDMMDTAKTVEPVESPQVRDVKTNGGTDCVCTGLNPEEESTVDAVDSENIPPIDSSCAEDAGKMEVELQEDGSHGMNTNNGKTSEPSQQALPAPLSSVDNPK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0048856 (anatomical structure development), GO:0060324 (face development), GO:0060322 (head development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: RING-type E3 ubiquitin transferase (A0A8M2BG80)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm. Nucleus, PML body
InterPro domains:
- IPR051073: ZNRF3/Arkadia E3 ubiquitin-protein ligases (family) [1-758]
- IPR029306: E3 ubiquitin-protein ligase Arkadia, N-terminal (domain) [1-300]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [944-1028]
- IPR001841: Zinc finger, RING-type (domain) [980-1022]
Sequence:
MKSEISADARQKQEPLKGPLANPEPMETAKSFPAEMEVIGKAGSDFTSPLCAETRHRPSRDAGGRRDCERGLSGRKKRKSQQPGPSYCSLKEAPMSEATLTPPRHRPMLLETRSEDERNPESSLSDCASSPSSSLRFGDSDTLSSDEDGMPMTVRQQLKAHGAASTGSTGSSTGTAVGIRPLLARTRASRSHKWARLEPDSNHVKRPCLGSRRPLHRKRFVKGGAGGVTQRTPKQKERLLLQRKKREVIARKKYALLHSTSSSSEEMTSDDSSPSSTEAEHELYVDVNSSSSQASTAAVASGVLDEDVVVIEATPAPAVPASEEINVTSTDSEVEIVTVGDAFRPRSVGGHGRMHWGPSCSQSRAQEGRGRHRLSTVIQPLRQSAGEVVDLTVDEDDLSVVPTTSDSTHPQPVSSSSSSSSRNACTSASPQEGPGPSSSCSAAAPDSTLAAQSHGGVPRSGTTNTTATEDESRRSLLGENGGVAMPRLPSCCPQHSPCSGPSSGHLSMGHTHSGCMQSGATQQSGPPQPGSQHSHTHSHHFHHHHHTAPVPSSLAYQESSCPLERPTAMPAPCGGVSNQYHDQQTLPVDLSSSAVRSSGSSSTGFHGTSAFDPCCPGSASRPPVYVSQAAPGPSQQTVADSFSPTIVAQPQPQPPQLSSCRHYMHPTYGSLSRPLHHQSSSSCPHSHSNAPPPQQPPPQGDYVIPHPVLPFHTPLPTHAPGHTVPTAPPPSLPSHHLPGSSAPLPQHLPPEHQALQHHLPVLGPNSVQRLHHHDLLQRMEVQRRRMMQHPTRAHERPPPHPHRMHPNYGHGHHIHVPQTMSSLPRQSDQRTTWELGIEAGVTVAPYPSGHLHPHLPHYHPPPRLHHFPIQLMHTGSMPEVTYPHIRYISSRMTFGRTYEDLLHLEERLGTVNRGASQGTIERCTYPHKYKKKVVERDTEEQLAPEAWASVGKKMHSTSNSRKLHGKQEEEEGAEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQLCVDQWLLTNKKCPICRVDIEAQLSSES
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity), GO:0061659 (ubiquitin-like protein ligase activity), GO:0061630 (ubiquitin protein ligase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0009790 (embryo development), GO:0048729 (tissue morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0009888 (tissue development), GO:0048731 (system development), GO:0007369 (gastrulation), GO:0002009 (morphogenesis of an epithelium), GO:0055113 (epiboly involved in gastrulation with mouth forming second), GO:0007399 (nervous system development), GO:0060429 (epithelium development), GO:0002011 (morphogenesis of an epithelial sheet), GO:0001702 (gastrulation with mouth forming second), GO:0090504 (epiboly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: RING-type E3 ubiquitin transferase (A0A8M1P6Z4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR050952: Tripartite Motif and NHL Repeat Containing E3 Ligases (family) [586-813]
- IPR001298: Filamin/ABP280 repeat (repeat) [428-528]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [428-530]
- IPR017907: Zinc finger, RING-type, conserved site (conserved_site) [55-64]
- IPR001841: Zinc finger, RING-type (domain) [12-82]
- IPR017868: Filamin/ABP280 repeat-like (repeat) [424-525]
- IPR000315: B-box-type zinc finger (domain) [136-259]
- IPR014756: Immunoglobulin E-set (homologous_superfamily) [430-525]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [5-113]
- IPR001258: NHL repeat (repeat) [538-813]
- IPR011042: Six-bladed beta-propeller, TolB-like (homologous_superfamily) [582-813]
Sequence:
MASFPDSDLQTCPLCKELCGCSAPISSNSSTSSSSSQTSNSSSTSSTRRLHVLPCLHAFCRQCLEGQRSPGDPLKLRCPTCDQKVSLSESGVDALPSSNFLFSNLLDVVVSAEEQGKNGRSSAVVHHGGLLRPQHLSDPQCSSCDEGNPATSHCLDCQEYLCDNCVRAHQRVRLTKDHFIEGLLESLHLANRTNNSNTPVSISQSFHNSFSMLNVFQERMDFCQHHDDAVLRFFCDSCTVPICRECSLGRHAGHSFTYLQDALQDSRALTIQLLADAQQGRQAIQLSIEKAQAIAEQVELKAKVVQSEVKTITLRHKKALEERECELLWKVEKIRQVKAKSLYLQVEKLHQNLTKLDSTIATVTQVLEEGRSIDVLLAREHMLNQLQELKSLRCILQPQEDDRIMFTPPDQALLIAIKSLGLISSGAFATASKAHGEGIKRALQGKPASFTVVGYDHDGEPRLSGGDSVSVVLMSPDGNLSSAEVSDHQDGTYTVSYLPKGEGEHLLSVLICNQHIEGSPFKVMVKSGRSYGGVGLPMASFGGEGDGDGQLCRPWGICVDKEGYVVVADRSNNRVQIFKPCGTFHHKFGTLGSRPGQFDRPAGVACDSQRRIIVADKDNHRIQIFTFDGQFLLKFGEKGTKNGQFNYPWDVAVNFEGKILVSDTRNHRVQLFGPDGTFLNKYGFEGALWKHFDSPRGVAFNQEGHLVVTDFNNHRLLVIRPDCQSARFLGSEGTGNGQFLRPQGVAVDQEDRIIVADSRNHRIQVFEPNGNFLCKFGTHGNGFGQMDRPSGIAVTPDGVIVAVDFGNNRILMF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009790 (embryo development), GO:0010171 (body morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0010172 (embryonic body morphogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0043229 (intracellular organelle), GO:0035770 (ribonucleoprotein granule), GO:0036464 (cytoplasmic ribonucleoprotein granule), GO:0045495 (pole plasm), GO:0043228 (non-membrane-bounded organelle), GO:0043186 (P granule), GO:0060293 (germ plasm), GO:0043232 (intracellular non-membrane-bounded organelle)
Protein: Voltage-gated potassium channel subunit beta-1 (A0A8M2B970)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side
InterPro domains:
- IPR023210: NADP-dependent oxidoreductase domain (domain) [139-456]
- IPR005400: Potassium channel, voltage-dependent, beta subunit, KCNAB1 (family) [358-455]
- IPR005983: Potassium channel, voltage-dependent, beta subunit, KCNAB (family) [124-457]
- IPR036812: NAD(P)-dependent oxidoreductase domain superfamily (homologous_superfamily) [123-463]
- IPR005399: Potassium channel, voltage-dependent, beta subunit, KCNAB-related (family) [85-469]
Sequence:
MFATHRSSLTELRVGHTGRRLSRQHSVPSEQVPKNGPPGNSVRRSSSISSSKLLSLSFSESMRSDIDRYLSDQGLYPLRQGGGEMGEIRSLREVRAAAQLKNLEDFLRSNGVSLQESISFQTGMRYRNLGKSGLRVSCLGLGTWVTFGGQITDEIAEQLMTLAYENGINLFDTAEVYAAGKAEMVLGSIIKKKGWRRSSLVITTKIYWGGKAETERGLSRKHIIEGLRASLERLQLEYVDVVFANRPDPNTPMEGDPFNTSKSRTFIIEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLIPPVCEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIISGKYDSGVPPCSRASLKGYQWMKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSCVLLGASSTDQLMENIGAIQVLPKLSSSIIHEVDSILGNKPYSKKDYRS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0016247 (channel regulator activity), GO:0005515 (protein binding), GO:0099106 (ion channel regulator activity), GO:0015459 (potassium channel regulator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0065008 (regulation of biological quality), GO:0098900 (regulation of action potential), GO:0051239 (regulation of multicellular organismal process), GO:0050794 (regulation of cellular process), GO:0010646 (regulation of cell communication), GO:0042391 (regulation of membrane potential), GO:0044057 (regulation of system process), GO:0051969 (regulation of transmission of nerve impulse), GO:0031644 (regulation of nervous system process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:1990351 (transporter complex), GO:0098797 (plasma membrane protein complex), GO:1902495 (transmembrane transporter complex), GO:0005886 (plasma membrane), GO:0034702 (ion channel complex), GO:0008076 (voltage-gated potassium channel complex), GO:0034703 (cation channel complex), GO:0034705 (potassium channel complex)