lokahq/bioreason-rl huggingface dataset:
Protein: Mitotic checkpoint protein BUB3 (Q9WVA3)
Organism: Mus musculus (Mouse)
Function: Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1 (By similarity). Regulates chromosome segregation during oocyte meiosis
Subcellular location: Nucleus. Chromosome, centromere, kinetochore. Note=Starts to localize at kinetochores in prometaphase I (Pro-MI) stage and maintains the localization until the metaphase I-anaphase I (MI-AI) transition
InterPro domains:
- IPR020472: PAC1/LIS1-like, WD-40 repeat (repeat) [30-263]
- IPR001680: WD40 repeat (repeat) [2-302]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [11-296]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [2-326]
Sequence:
MTGSNEFKLNQPPEDGISSVKFSPNTSQFLLVSSWDTSVRLYDVPANSMRLKYQHTGAVLDCAFYDPTHAWSGGLDHQLKMHDLNTDQENLVGTHDAPIRCVEYCPEVNVMVTGSWDQTVKLWDPRTPCNAGTFSQPEKVYTLSVSGDRLIVGTAGRRVLVWDLRNMGYVQQRRESSLKYQTRCIRAFPNKQGYVLSSIEGRVAVEYLDPSPEVQKKKYAFKCHRLKENNIEQIYPVNAISFHNIHNTFATGGSDGFVNIWDPFNKKRLCQFHRYPTSIASLAFSNDGTTLAIASSYMYEMDDTEHPEDGIFIRQVTDAETKPKST
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050794 (regulation of cellular process), GO:0051726 (regulation of cell cycle), GO:0010564 (regulation of cell cycle process), GO:0051983 (regulation of chromosome segregation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0098687 (chromosomal region), GO:0099080 (supramolecular complex), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000775 (chromosome, centromeric region), GO:0000776 (kinetochore), GO:0043228 (non-membrane-bounded organelle), GO:0000779 (condensed chromosome, centromeric region), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005694 (chromosome), GO:0005634 (nucleus), GO:0000793 (condensed chromosome)
Protein: Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (A0A2C9JXL4)
Organism: Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail)
Function: Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins
Subcellular location: Membrane; Single- pass type II membrane protein
InterPro domains:
- IPR026050: C1GALT1/C1GALT1-specific chaperone 1 (family) [13-340]
- IPR003378: Fringe-like, glycosyltransferase domain (domain) [103-260]
Sequence:
MAPISHYIGKTSLTTLAIGIAIGITVSNIVKFSSTQRRHFSSSGYIPDSPHSHGENDFVEGPDDSLSWHDEHSHSHKFENDSVARQLFKKVRVLCWVMTNPNNIHTKARHVKATWGKRCNVLLFMSSRADRDLPALALNVQEGRDNLWAKTKEAFKLIHSKYLETADWFIKCDDDTFLVLENLRYFLQDKSPSEPVYYGRKFKPIVQQGYMSGGAGYVLSKESLVRLVTQGIGHKEDCRADSGGAEDVEMGRCLQSVNVQAGDSRDELGRERFHPFVPEHHLIPDILPPDMWYWSYNFYPAKQGQECCSDYAISFHYVPPNMMYVLEYLVYHLKPYGITSAYESTEEQDHGSSHKDTDAMKPEGKGMEDKEDEETNISLAQTDSKHIS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016758 (hexosyltransferase activity), GO:0008378 (galactosyltransferase activity), GO:0048531 (beta-1,3-galactosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0070085 (glycosylation), GO:0044249 (cellular biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0043413 (macromolecule glycosylation), GO:1901135 (carbohydrate derivative metabolic process), GO:0019538 (protein metabolic process), GO:0036211 (protein modification process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0009059 (macromolecule biosynthetic process), GO:0006486 (protein glycosylation), GO:0043412 (macromolecule modification), GO:0034645 (cellular macromolecule biosynthetic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0009100 (glycoprotein metabolic process), GO:0009101 (glycoprotein biosynthetic process), GO:0006493 (protein O-linked glycosylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Arginine permease CAN1 (Q6FNY1)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 /
Function: High-affinity permease for arginine. May also transport other basic amino acids (By similarity)
Subcellular location: Cell membrane; Multi-pass membrane protein
InterPro domains:
- IPR004841: Amino acid permease/ SLC12A domain (domain) [99-563]
- IPR050524: Amino Acid-Polyamine-Organocation Superfamily YAT (family) [65-594]
- IPR004762: Amino acid permease, fungi (family) [92-569]
- IPR004840: Amino acid permease, conserved site (conserved_site) [124-155]
Sequence:
MKFRNILKNEKNEKNEASASTSHASEDIEIIPSRYDNEKFYSATEATHKKKTGSTGFDDTISLTHTLSRSRIPTSMEDEDAEEAEVHDTRVKRALKQRHIGMIALGGTIGTGLFVGISTPLSNSGPVGALIAYIFMGTIIYFVTQSLGEMATFIPVTSSITVFSKRFLSPAFGVANGYMYWFNWAITYAVEVSVIGQVIQYWTFKVPLAAWIGIFWVLITLMNFFPVKIYGEFEFWVASIKVIAIVGYLIYALIIVCGGSHQGPIGFRYWRNPGAMGAGIISSDLGEARFLGWVSSLINAAFTYQGTELVGITAGEAANPRKSVPRAINKVVFRIVLFYIMSLFFVGLLVPYNDPRLSASSAVIASSPFVISIQNAGTKVLPDIFNAVVLVTVISAANSNVYVGSRVLYALAQSGNAPKQFAYVTRHGVPYLGVICTALLGLLAFLVVNHNANTAFNWLINISTLAGLCAWLFISLAHIRFMQALKFRGISRDDLPFKAKFMPWGAYYASFFVTVIIFIQGFQAFAPKFDVSEFFTAYISLILLVVLFAGCQLYYRCRFLWKLEDIDIDSDRREIDAIVWEDDEPQNLWEKFWAAVA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0008514 (organic anion transmembrane transporter activity), GO:0005342 (organic acid transmembrane transporter activity), GO:0072349 (modified amino acid transmembrane transporter activity), GO:0046943 (carboxylic acid transmembrane transporter activity), GO:0061459 (L-arginine transmembrane transporter activity), GO:0015171 (amino acid transmembrane transporter activity), GO:0015174 (basic amino acid transmembrane transporter activity), GO:0015179 (L-amino acid transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0009987 (cellular process), GO:0055085 (transmembrane transport), GO:0051234 (establishment of localization), GO:1903825 (organic acid transmembrane transport), GO:0006810 (transport), GO:0071705 (nitrogen compound transport), GO:0071702 (organic substance transport), GO:1905039 (carboxylic acid transmembrane transport), GO:0015711 (organic anion transport), GO:0003333 (amino acid transmembrane transport), GO:0072337 (modified amino acid transport), GO:0006865 (amino acid transport), GO:0015849 (organic acid transport), GO:0046942 (carboxylic acid transport), GO:0015807 (L-amino acid transport), GO:1902475 (L-alpha-amino acid transmembrane transport), GO:1902022 (L-lysine transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Protein C2-DOMAIN ABA-RELATED 9 (Q9S7J9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Stimulates the GTPase/ATPase activities of Obg-like ATPases (By similarity). Mediates the transient calcium-dependent interaction of PYR/PYL/RCAR abscisic acid (ABA) receptors with the plasma membrane and thus regulates ABA sensitivity
Subcellular location: Cell membrane. Nucleus. Note=Localization at the plasma membrane increases upon abscisic acid (ABA) treatment, at the expense of nuclear localization
InterPro domains:
- IPR000008: C2 domain (domain) [1-104]
- IPR035892: C2 domain superfamily (homologous_superfamily) [2-167]
- IPR044562: Protein C2-DOMAIN ABA-RELATED (family) [6-166]
Sequence:
MEDKPLGILRVHVKRGINLAIRDATTSDPYVVITLANQKLKTRVINNNCNPVWNEQLTLSIKDVNDPIRLTVFDKDRFSGDDKMGDAEIDFRPFLEAHQMELDFQKLPNGCAIKRIRPGRTNCLAEESSITWSNGKIMQEMILRLKNVECGEVELMLEWTDGPGCKGLGREGSKKTPWMPTKRLD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0008289 (lipid binding), GO:0005515 (protein binding), GO:0043169 (cation binding), GO:0005543 (phospholipid binding), GO:0046872 (metal ion binding), GO:0005509 (calcium ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023056 (positive regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0010647 (positive regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:1905957 (regulation of cellular response to alcohol), GO:0010646 (regulation of cell communication), GO:1901419 (regulation of response to alcohol), GO:0009787 (regulation of abscisic acid-activated signaling pathway), GO:0009789 (positive regulation of abscisic acid-activated signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0005773 (vacuole), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0000325 (plant-type vacuole), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Carboxypeptidase B1 (A0A1S4F020)
Organism: Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
Function: Carboxypeptidase that preferentially hydrolyzes arginine and lysine residues at the C-terminus. During infection by dengue virus, may play a role in preventing viral packaging, maturation, and release from the midgut
Subcellular location: Endoplasmic reticulum
InterPro domains:
- IPR003146: Carboxypeptidase, activation peptide (domain) [29-95]
- IPR000834: Peptidase M14, carboxypeptidase A (domain) [118-408]
- IPR036990: Metallocarboxypeptidase-like, propeptide (homologous_superfamily) [19-106]
Sequence:
MIPRIVVVLLSVLAVVTARRSYEGYKVYGIVPESPDEAEILYQIRQSNPDLDFWHLTKQPGDEARVLVAPKDQRSFLIKLIRHGLHYQEVISDVEGTLAPYNEPRTRGMSLDRDVSTSYLRHNEINEYLQTLSQKYPSLVSVEEAGTSYEGRSIKTITINKKPGNAVVFLDAGIHAREWIAPATALYAIEQLVEHSSENQEVLSNLTWVIMPVVNPDGYEFSHETDRFWRKTRKPTGKTCKGTDGNRNFDYHWGEVGASTQACADTFRGETAFSEPETRAVRDAVMKLKGSCKFYLSLHSYGNYILYPWGWTSKLPETWEAIDEVAQAGAEAIKQSTGSRYTVGSSTNVLYAAAGGSDDWAFAVAEVPISITMELPGGGNGGFNPPPSSIEKIVNESWVGIKAMALKVAQMF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0006508 (proteolysis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Coiled-coil domain-containing protein 113 (Q8C5T8)
Organism: Mus musculus (Mouse)
Function: Component of centriolar satellites contributing to primary cilium formation
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite . Note=Colocalized with HAP1 at centriolar satellites. Centriolar satellite localization requires PCM1
InterPro domains:
- IPR025254: CCDC113/CCDC96, coiled-coil (domain) [180-353]
- IPR051885: Coiled-coil domain-containing protein involved in ciliogenesis (family) [12-369]
Sequence:
MSEEDSDSVITDSQAEEEGELPVIQLCGLVEELSYGNSALKTETEMFEKYYSRLEPRDHRMTRLSDIKITAAEFSQLRSRRKSKARGGLDRTLGLTVEQKLELVQKELEDTRDEIRHMRANAERDLQHHEAIIEEADIRWNEVQKAVHEFEKDILKTISKKKGSILATQKVMKYIEDMNRRRDNIKDKLCLKNVSLKVQRKKMLSQLRQKEEVGEALHDVDFQQLKIENAQFLETIEARNKELIQLKLASGNTLQVLNTYKNKLHRAMEIYVNLDKEILLRNELLGKIEKETIQAEEDRAKAHILNDKLRKQLAEFRAPQVMMYVKEKILNGELEKTIKMWERKVEIAEMSLKGYRKAWNKMKTSDEQLQIIRPPGK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0006996 (organelle organization), GO:0030030 (cell projection organization), GO:0022607 (cellular component assembly), GO:0044782 (cilium organization), GO:0070925 (organelle assembly), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0060271 (cilium assembly), GO:0120031 (plasma membrane bounded cell projection assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0034451 (centriolar satellite), GO:0036064 (ciliary basal body), GO:0120025 (plasma membrane bounded cell projection), GO:0005813 (centrosome), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0005929 (cilium), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015630 (microtubule cytoskeleton)
Protein: Coiled-coil domain-containing protein 38 (Q8CDN8)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
InterPro domains:
- IPR025252: Domain of unknown function DUF4200 (domain) [112-230]
- IPR051147: Cilia- and flagella-associated domain-containing protein (family) [23-561]
Sequence:
MASQMHTSISSGDEGKDAVLKKERPYKIFFKDLFVFKENEIAARKKERMKNHSMKIYQKTTFSSRMKSRSHLGQLAFFADAGSSSYERLGLDPTLILRLTEGADRKRTVHEFINDQRDRFLLEYTVSTKKKTIKRFERLIAIKENQLKKAEKKLQDDALSFEEFLRENDQRSVDALKMAAQETINKLQMTSELKKASMEVQSIKSDIAKTEFLLKEYMKYGFFLLKLSPKQWQIQQSQKRAQSSKSNHILPKILEKFSINTAKGDNSIDSDKMSVSEEWSSRRGSQGGRHGKHTLGQDSRKSSGFTRPESMASEDSLEYFLEDELVEFDLLPEIYFKEPEELLQVFTELEEQNLTLVQYSQDVDENLEDVNKREKFIQDKINNNISFLLEHKHMLRMNCEREEEKAAELELRSRLFSFGEFNSDAQEKLIDSLSKKINQVYRVCIGDAEVGSLNAVQKLVKVESRLVELSDLIESIPREHVEAIERLKQKERRQKLREEKMKEKQRHQEERLKAALERAVAQPKKKLGRRLIYRSKPQSADKQELLLVSDTRSKSQDEEYFFS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0007276 (gamete generation), GO:0007281 (germ cell development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0007283 (spermatogenesis), GO:0048515 (spermatid differentiation), GO:0007286 (spermatid development), GO:0048232 (male gamete generation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0043229 (intracellular organelle), GO:0036064 (ciliary basal body), GO:0043227 (membrane-bounded organelle), GO:0120025 (plasma membrane bounded cell projection), GO:0043228 (non-membrane-bounded organelle), GO:0005929 (cilium), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015630 (microtubule cytoskeleton)
Protein: Cell cycle regulator CcrZ (Q8DQV8)
Organism: Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
Function: Plays a role in cell cycle regulation and chromosome integrity. Activates DnaA-dependent chromosomal DNA replication initiation ensuring that the chromosome is replicated at the right time during the cell cycle (By similarity). May regulate replication initiation through phosphorylation of a possible second messenger or metabolite, and by interacting with replication initiation proteins. Has ATPase activity with D-ribose and 2-deoxy-D-ribose in vitro, but not with choline. Involved in DNA damage response (By similarity)
Subcellular location: Cytoplasm. Note=Localizes at mid-cell, forming a patchy ring. Disassembles from the old septum to assemble at the newly formed division site. Colocalizes with FtsZ during the full cell cycle. Colocalizes with DnaA in newborn cells (By similarity)
InterPro domains:
- IPR052077: Cell Cycle Regulator and Phase Variation Mediator (family) [13-260]
- IPR002575: Aminoglycoside phosphotransferase (domain) [44-215]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [3-226]
Sequence:
MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGLAREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQLSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDVRHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTVLSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0006950 (response to stress), GO:0006979 (response to oxidative stress)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Cilia- and flagella-associated protein 53 (Q96M91)
Organism: Homo sapiens (Human)
Function: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating. May play a role in the beating of primary cilia and thereby be involved in the establishment of organ laterality during embryogenesis
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme
InterPro domains:
- IPR043597: Trichohyalin-plectin-homology domain (domain) [158-485]
- IPR043596: CFAP53/TCHP (family) [24-510]
Sequence:
MYSQRFGTVQREVKGPTPKVVIVRSKPPKGQGAEHHLERIRRSHQKHNAILASIKSSERDRLKAEWDQHNDCKILDSLVRARIKDAVQGFIINIEERRNKLRELLALEENEYFTEMQLKKETIEEKKDRMREKTKLLKEKNEKERQDFVAEKLDQQFRERCEELRVELLSIHQKKVCEERKAQIAFNEELSRQKLVEEQMFSKLWEEDRLAKEKREAQEARRQKELMENTRLGLNAQITSIKAQRQATQLLKEEEARLVESNNAQIKHENEQDMLKKQKAKQETRTILQKALQERIEHIQQEYRDEQDLNMKLVQRALQDLQEEADKKKQKREDMIREQKIYHKYLAQRREEEKAQEKEFDRILEEDKAKKLAEKDKELRLEKEARRQLVDEVMCTRKLQVQEKLQREAKEQEERAMEQKHINESLKELNCEEKENFARRQRLAQEYRKQLQMQIAYQQQSQEAEKEEKRREFEAGVAANKMCLDKVQEVLSTHQVLPQNIHPMRKACPSKLPP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0007389 (pattern specification process), GO:0003002 (regionalization), GO:0009799 (specification of symmetry), GO:0009855 (determination of bilateral symmetry), GO:0060972 (left/right pattern formation), GO:0007368 (determination of left/right symmetry)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0005930 (axoneme), GO:0034451 (centriolar satellite), GO:0005737 (cytoplasm), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0099568 (cytoplasmic region), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0005813 (centrosome), GO:0005929 (cilium), GO:0032838 (plasma membrane bounded cell projection cytoplasm), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0097014 (ciliary plasm), GO:0031514 (motile cilium), GO:0097729 (9+2 motile cilium), GO:0015630 (microtubule cytoskeleton), GO:0036126 (sperm flagellum)