Protein: tissue kallikrein (A6JAL5)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR043504: Peptidase S1, PA clan, chymotrypsin-like fold (homologous_superfamily) [27-254]
- IPR009003: Peptidase S1, PA clan (homologous_superfamily) [25-258]
- IPR033116: Serine proteases, trypsin family, serine active site (active_site) [207-218]
- IPR001254: Serine proteases, trypsin domain (domain) [24-258]
- IPR001314: Peptidase S1A, chymotrypsin family (family) [51-218]
- IPR018114: Serine proteases, trypsin family, histidine active site (active_site) [61-66]
Sequence:
MWFLILFLDLSLGQIDAAPPGQSRVIGGYKCEKNSQPWQVALYSFSKYLCGGVLIDPSWVITAAHCSSNNYQVWLGRNNLLEDEPFAQHRLVSQSFPHPDYKPFLMRNHTRKPGDDHSNDLMLLHLSQPADITDGVKVIDLPTEEPKVGSTCLASGWGSTKPLIWEFPDDLQCVNIHLLSNEKCIKAYKEKVTDLMLCAGELEGGKDTCTGDSGGPLLCDGVLQGITSWGSVPCAKTNMPAIYTKLIKFTSWIKEVMKENP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0008233 (peptidase activity), GO:0004175 (endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0009991 (response to extracellular stimulus), GO:0032101 (regulation of response to external stimulus), GO:0010942 (positive regulation of cell death), GO:0032103 (positive regulation of response to external stimulus), GO:0031349 (positive regulation of defense response), GO:0042127 (regulation of cell population proliferation), GO:0010941 (regulation of cell death), GO:0007584 (response to nutrient), GO:0080134 (regulation of response to stress), GO:0008284 (positive regulation of cell population proliferation), GO:0031347 (regulation of defense response), GO:0050727 (regulation of inflammatory response), GO:0043067 (regulation of programmed cell death), GO:0031667 (response to nutrient levels), GO:0043068 (positive regulation of programmed cell death), GO:0050729 (positive regulation of inflammatory response), GO:0002673 (regulation of acute inflammatory response), GO:0002675 (positive regulation of acute inflammatory response), GO:0043065 (positive regulation of apoptotic process), GO:0042981 (regulation of apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0045177 (apical part of cell), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0030141 (secretory granule), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0001669 (acrosomal vesicle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle), GO:0005634 (nucleus)