lokahq/bioreason-rl huggingface dataset:
Protein: Calcium/calmodulin-dependent protein kinase IG isoform X2 (A0A8M9PSZ5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [189-201]
- IPR017441: Protein kinase, ATP binding site (binding_site) [80-107]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [74-328]
- IPR000719: Protein kinase domain (domain) [74-327]
Sequence:
MSVSLRSAQFPLPSHVILCHCCPCLRLDSFCKRQKSCWSCYRPEEIPVEAHAEMGRKEGEYEWKKSTDNIQDVFDFMDVLGSGAFSEVFMVKERKTGKLFAMKCVKKKNKRDINLENEIAVLRKIKHENVVCLEDFYESRTHYYLVMQLVSGGELFDRILDRGMYSEMDASSVIRQVLEAVSYLHNNGIVHRDLKPENLLYYSPDENSKIMISDFGLSKMEDNGVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETETRLFSKIMKGQYEFDSPFWDDISESAKDFIRNMMQKNPKMRFNTEQALRHPWIIGKTARSQDIYHSVSEQMQKNFAKSKWKQAFNATVAINHMKKLQQAHSEACVRLKDSPRDVPEIKVIASSTPESVRKKLLSETPEPNGSMNVPCGSTEAKSQYHPMRVSHSETTHVGTLTIAEKGKHVYHSEPADLNGYAKRSSNRPGQNLQTGVCSVM
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity), GO:0004683 (calmodulin-dependent protein kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0048511 (rhythmic process), GO:0007610 (behavior), GO:0007623 (circadian rhythm), GO:0007626 (locomotory behavior), GO:0048512 (circadian behavior), GO:0007622 (rhythmic behavior), GO:0045475 (locomotor rhythm)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Protein farnesyltransferase subunit beta (A0A8M9PP61)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding
InterPro domains:
- IPR001330: Prenyltransferase alpha-alpha toroid domain (domain) [58-359]
- IPR045089: Prenyltransferase subunit beta (family) [186-372]
- IPR008930: Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid (homologous_superfamily) [19-375]
- IPR026872: Protein farnesyltransferase subunit beta (family) [60-329]
Sequence:
MEEAPPSLRCFQESHSSELFNDDGLQTVTSREQRKVERSIQEVYSVYQQIHTSPQPALLREQHYHYLKKGLRHLSDAYECLDASRPWLCYWILHSLELLEEPVPAAVASDVCQFLARCQAPTGGFGGGPGQQAHLAPTYAAVNALCILGTEEAYNVINRETLLDFLYSVKQPDGSFVMHIGGEVDVSCQNWEGGLGGVPGLEAHGGYTFCGTAALVILGKEHMLDLKALLRWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALFKEGDSTLSVSSWMFERKALQEYILLCCQNPGGGLLDKPGKSRDFYHTSYCLSGLSVAQHFGNKDLHNELILGRDENKLAPTHPVYNICPEKVARAVEYFHRLPVPIPTGATASAMDQS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0003205 (cardiac chamber development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0072359 (circulatory system development), GO:0003231 (cardiac ventricle development), GO:0007507 (heart development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Muscleblind-like protein 2 isoform X2 (A0A8M3AWR8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm. Nucleus
InterPro domains:
- IPR000571: Zinc finger, CCCH-type (domain) [13-238]
- IPR054429: Muscleblind-like, CCCH zinc finger (domain) [48-251]
Sequence:
MALNIASIRDTKWLTLEVCRQFQRGTCSRSDEECKFAHPPKSCQVENGRVIACFDSLKGRCTRENCKYLHPPAHLKTQLEINGRNNLIQQKTAAAMLAQQMQFMIPGTTMQPVPTFPVSQGLGSNPGLSYAPYLTPMSHGMGLVPTEMLPSTPVIVPGSPPVSVPSSSSTQKLLRTDKLEVCREFQRGNCARGETDCRFAHPSDSPMIDTSDNTVTVCMDYIKSRCSREKCKYFHPPAHLQAKIKAAQHQANQTAVAAQAAAAAMTQSTAKAMKRPLEASVDLAFPHGVLQPLPKRPALEKSNGASTLFNPSVLHYQQALASAQLQQPTAAFFPTGSVLCMAPASSIVPMMYSATPATVSAATTPATSVPYATTAPANQIILK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0001069 (regulatory region RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009790 (embryo development), GO:0061061 (muscle structure development), GO:0048513 (animal organ development), GO:0048731 (system development), GO:0007517 (muscle organ development), GO:0048880 (sensory system development), GO:0072359 (circulatory system development), GO:0007507 (heart development), GO:0009792 (embryo development ending in birth or egg hatching), GO:0007423 (sensory organ development), GO:0043009 (chordate embryonic development), GO:0150063 (visual system development), GO:0001654 (eye development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Tubulin beta chain (A0A8M2BKU1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin
Subcellular location: Cytoplasm, cytoskeleton
InterPro domains:
- IPR023123: Tubulin, C-terminal (homologous_superfamily) [373-443]
- IPR013838: Beta tubulin, autoregulation binding site (binding_site) [1-4]
- IPR002453: Beta tubulin (family) [41-429]
- IPR003008: Tubulin/FtsZ, GTPase domain (domain) [3-243]
- IPR000217: Tubulin (family) [2-425]
- IPR008280: Tubulin/FtsZ, C-terminal (homologous_superfamily) [243-428]
- IPR018316: Tubulin/FtsZ, 2-layer sandwich domain (domain) [245-382]
- IPR017975: Tubulin, conserved site (conserved_site) [139-145]
- IPR036525: Tubulin/FtsZ, GTPase domain superfamily (homologous_superfamily) [1-262]
- IPR037103: Tubulin/FtsZ-like, C-terminal domain (homologous_superfamily) [263-372]
Sequence:
MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEEAEDDA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0040007 (growth), GO:0048589 (developmental growth), GO:0048856 (anatomical structure development), GO:0031099 (regeneration), GO:0042246 (tissue regeneration), GO:0031101 (fin regeneration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0099513 (polymeric cytoskeletal fiber), GO:0005874 (microtubule), GO:0015630 (microtubule cytoskeleton)
Protein: KISS1 receptor b isoform X2 (A0A8M3B305)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
Sequence:
MAETNSTGDAAEHIMCNYDANIYQCNQTDLMRFQNPVPLTDTWLVPLFFTLIMFVGLVGNLIVIYVVIKNQQMKTVTNLYIVNLATTDILFLVCCVPFTATVYVLPSWIFGDFMCRLVNYLQQVTAQATCITLSAMSVDRFYVTVYPLQSLHHRTPQMALSVCTTIWICSSLLSVPIALYQHTESSYWFGPQTYCTETFPSVIHKRVYLLYSFLAVYLLPLITICMCYTFMLKRMAQATVQPVQGCNQVSPFIDQGSPHEPPTSPAYVFTADALSL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0001653 (peptide receptor activity), GO:0008528 (G protein-coupled peptide receptor activity), GO:0004930 (G protein-coupled receptor activity), GO:0008188 (neuropeptide receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048522 (positive regulation of cellular process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009891 (positive regulation of biosynthetic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0010468 (regulation of gene expression), GO:1902680 (positive regulation of RNA biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0045893 (positive regulation of DNA-templated transcription), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Tyrosine-protein phosphatase auxilin isoform X2 (A0A8M9QG43)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR029021: Protein-tyrosine phosphatase-like (homologous_superfamily) [117-276]
- IPR001623: DnaJ domain (domain) [909-974]
- IPR029023: Tensin-type phosphatase domain (domain) [109-276]
- IPR014020: Tensin phosphatase, C2 domain (domain) [280-417]
- IPR036869: Chaperone J-domain superfamily (homologous_superfamily) [797-974]
- IPR035892: C2 domain superfamily (homologous_superfamily) [281-414]
Sequence:
MSLLGGYKKKSSYDGYESLQLVDSSGDFSTGGRSGGGGGGGLTAVTLGSVKTGPARQDDYSTMDSSDMDGNYGGGLLDMVKGGAGKFFSNIKDNLKDTIKDTSTKVMNQVATYTKGELDIAYITSRIIVMSYPAETVEMGYRNHTEDIRSFLDSRHADHYTVFNLSQRNYRGAKFSNRVSECNWPSRQAPSLHNLFAVCKNMYNWLKQNPKNVCVITCSDGRAPSGVLVCAMFCFCHLFANPVPAMQLLSAKRPGSGLWPSHRRYIGYVCSLVSEKPTVPHSKPLVIKTVTISPVPCFNKQRSGCRPFCDVLIGETKIFSTAQEYERMREHRIQEGKVVFPVGVSAQGDVVISVYHMRSHALQAKVTNTQIFQIQFHTGFIAPGSTVLKFMKTELDACDSPEKYPQLFHVLIDIEVESTEKQKDLTPPWEQFPTKDLSPNVLFSCHQEHQDALAIADEMEGLDLEDPAQGHSSCGGRVGPNEESEPSDDEMLSLSSQQSNASNEKSKAAKRPEPQAAAPPPPAAEEVDLLGLDGDAAKIPPSSPQPPANNTTTDLLGDLFGAPPTPQPASCPGSAQSTPRRSAQSSSPGPSPRSGNTFDPFGSGPAPAPKPQDFMGAFLGPGNMGQPDPFLHAARSPSPTMQNMGMGRSSPVPPSTPTVNIQQQNSTGAWEWNKPAAAGGGFGMGSKSASTSPTSSAHGTPTHQTKPNTLDPFADLGNLGAGLGGGGSGFSSKPTTPTGTGGAFPPMGSPQRPAPSPQHTASGGWHPNTGFPSWQAGGGAQWQPQAQGTPTKAPPASMPHTSPQNRPNYNVSFSAMSGASPGAAGPKAQPNMGTRPKVSDANFDDLLSGQGFAGGKEKKGPKTIAEMRKEEMAKEMDPEKLKILDWIEGKERNIRALLSTMHTVLWEGETRWKPVGMADLVTPEQVKKVYRKAVLVVHPDKATGQPYEQYAKMIFMELNDAWSEFESQGQKALY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0060090 (molecular adaptor activity), GO:0005515 (protein binding), GO:0030276 (clathrin binding), GO:0019904 (protein domain specific binding), GO:0032050 (clathrin heavy chain binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065008 (regulation of biological quality), GO:0023051 (regulation of signaling), GO:0003008 (system process), GO:0050794 (regulation of cellular process), GO:0007610 (behavior), GO:0048167 (regulation of synaptic plasticity), GO:0050877 (nervous system process), GO:0099177 (regulation of trans-synaptic signaling), GO:0010646 (regulation of cell communication), GO:0007611 (learning or memory), GO:0048168 (regulation of neuronal synaptic plasticity), GO:0007613 (memory), GO:0050890 (cognition), GO:0050804 (modulation of chemical synaptic transmission), GO:0007616 (long-term memory)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0048471 (perinuclear region of cytoplasm), GO:0005737 (cytoplasm)
Protein: SURF1-like protein (A0A8M3B2I7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Probably involved in the biogenesis of the COX complex
Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein
InterPro domains:
- IPR002994: Surfeit locus 1/Shy1 (family) [1-189]
- IPR045214: Surfeit locus 1/4 (family) [2-184]
Sequence:
MEIKQLEYRRVKVRGHFDHSKELYILPRSPVDPEREAREAGRISSSGESGANVITPFFCTDLGITILVNRGYVPKNKIKPETRTKGQVIEDVDLVGVVRLTEQRKPFVPENNVEANRWHYRDLEAMAKVTGAEEIFIDAVLDSTVPGGPIGGQTRVTLRNEHLQYVITWYGLCAATSYMWYAKFIKRIAL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0016491 (oxidoreductase activity), GO:0009055 (electron transfer activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0016675 (oxidoreductase activity, acting on a heme group of donors), GO:0022804 (active transmembrane transporter activity), GO:0015399 (primary active transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0022853 (active monoatomic ion transmembrane transporter activity), GO:0004129 (cytochrome-c oxidase activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0015453 (oxidoreduction-driven active transmembrane transporter activity), GO:0015078 (proton transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0035295 (tube development), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009888 (tissue development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0048731 (system development), GO:0030324 (lung development), GO:0030323 (respiratory tube development), GO:0051246 (regulation of protein metabolic process), GO:0060429 (epithelium development), GO:0051052 (regulation of DNA metabolic process), GO:0072359 (circulatory system development), GO:0007507 (heart development), GO:0060541 (respiratory system development), GO:0044030 (regulation of DNA methylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Short stature homeobox protein 2 isoform X2 (A0A8M9QLB7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
- IPR000047: Helix-turn-helix motif (conserved_site) [71-96]
- IPR017970: Homeobox, conserved site (conserved_site) [75-98]
- IPR003654: OAR domain (domain) [212-229]
- IPR001356: Homeodomain (domain) [40-104]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [38-104]
- IPR052631: Paired homeobox Bicoid subfamily (family) [6-233]
Sequence:
MLASERSRDSSSPKLTDGNTDMKERKEDCKPLEDETQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIGAASQFEACRVAPYVNVGALRMPFQQDSHCNVPPFSFQVQAQLQLDSAVAHAHHHLHSHLAAHAPYMMFPAPPFGLPLATLAAESASAASVVAAAAAAKTTNKNSSIADLRLKAKKHAAALGL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0051239 (regulation of multicellular organismal process), GO:0048731 (system development), GO:0044057 (regulation of system process), GO:0048513 (animal organ development), GO:1903522 (regulation of blood circulation), GO:0072359 (circulatory system development), GO:0007507 (heart development), GO:0008016 (regulation of heart contraction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Inositol polyphosphate-5-phosphatase K isoform X1 (A0A8M3AHJ9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR036691: Endonuclease/exonuclease/phosphatase superfamily (homologous_superfamily) [63-425]
- IPR046985: Inositol 5-phosphatase (family) [34-482]
- IPR000300: Inositol polyphosphate-related phosphatase (domain) [83-416]
- IPR041611: SKICH domain (domain) [421-521]
Sequence:
MSSSMEEISEYFSEKLQRQRSDSAASSSTQSTSSRQHVRQRLAMLLTCVDDLDTDHKLQTQVAKTLDEAFLVCRQIAGRPKKNPFRLYVVTWNVATAEPPDDVNALLQLNSPKKPDLYVIGLQEVRAAPLKFVSDLAFEDSWSHLFMDTLSPLHYIKVSSIRMQGLLLLFFSKLEHVPFIRDIQVTYTRTGLYGYWGNKGGVTIRLSFYGHMLCFLNCHLTAHMNYASQRVDEFEHILDAQNFNTKNTPHVLDHKVVFWFGDLNFRIEDHGMLFVRNCITSQRFNLLWPKDQLTMMKQKEVILQKFEEGPLDFQPTYKFDLNSDNYDTRVQTTWFGFNGKKRKPAWCDRILWRVKPKASLTENTNEEEPEKQQEEEREDEFPLKMTQEYYTSKMEYGISDHKPVIGIFRLELRKMYETPLVQVFAEGEWSADFDAVITYRLLQAFASSAWDWIGLYKVGFKSVSDYITYAWVKDDQVSFNEELFQVYMNKDEIPVLGGECVLCYYSSNLQCIVGISQPFKVQESRAAIEEGLVPENINGLNQALAS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0016791 (phosphatase activity), GO:0052866 (phosphatidylinositol phosphate phosphatase activity), GO:0034595 (phosphatidylinositol phosphate 5-phosphatase activity), GO:0034594 (phosphatidylinositol trisphosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0061061 (muscle structure development), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007517 (muscle organ development), GO:0042692 (muscle cell differentiation), GO:0048880 (sensory system development), GO:0055001 (muscle cell development), GO:0060537 (muscle tissue development), GO:0007423 (sensory organ development), GO:0007519 (skeletal muscle tissue development), GO:0060538 (skeletal muscle organ development), GO:0150063 (visual system development), GO:0014904 (myotube cell development), GO:0001654 (eye development), GO:0051146 (striated muscle cell differentiation), GO:0014902 (myotube differentiation), GO:0043010 (camera-type eye development), GO:0048741 (skeletal muscle fiber development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)