Protein: Centrosomal protein of 70 kDa (A0A8M6Z3B7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle
InterPro domains:
- IPR037692: Centrosomal protein of 70kDa (family) [20-628]
Sequence:
MDRQALQSRDKTYVFLWTYSQFQEEQREWDAVNRLLQHHGFKPVSFADPKENKNLAELVLLERKSASDVRLMLKTMLSDSERRQGLIQELIQSNSQLKEEVQQHQTRAARQSQRAAELENILDGVKVKVQDLEDSYISKAAQQHQQFQQLQQEKRDAEKCCQSVEQKLIQEQQQASRLQKKLQYAVREEERRATRQKQTFQQILHRSARPNSTNDQQILDIIDLYESQMQQLRNELKLYKGEKDSSNSQKSRSTVDKDVIDASSTYKTLLKSYQEQLKESKAQREELRTEIQRLKEDLESRPTIKELKTCKQQLRRLDRIIQQSNLRSAQELKPQDSTEKPDTDNASIQSLDISTCRRLLTDVCKELDVQNINHLISTVNAQRNQAGSAFRLQKILYDITAVLTDHRAPLGLLRQRVPSNLEFNEEFDMIVPSLEVWSQQLTSLSDLHHALINLQKRLLPLQPESGSTALSDSVRVEDLMLIVDTLLDETQPDDKVLRSPTRHTLESIVAHFQKLFDVPSLTGIYPRMTELYSKLGEMNNAMRNLRDLLDLDDKAPASEVVSSVSSVLSQSGQEICSLLESSDIDSIILKLKEHEEFFPAFHSFMLELLQTLDVQTLDDVLPRIRSLKG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0007389 (pattern specification process), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0007017 (microtubule-based process), GO:0007018 (microtubule-based movement), GO:0044085 (cellular component biogenesis), GO:0003002 (regionalization), GO:0006810 (transport), GO:0009799 (specification of symmetry), GO:0016043 (cellular component organization), GO:0009855 (determination of bilateral symmetry), GO:0006858 (extracellular transport), GO:0030030 (cell projection organization), GO:0003341 (cilium movement), GO:0060972 (left/right pattern formation), GO:0006996 (organelle organization), GO:0099111 (microtubule-based transport), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0007368 (determination of left/right symmetry), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0044782 (cilium organization), GO:0003351 (epithelial cilium movement involved in extracellular fluid movement), GO:0120031 (plasma membrane bounded cell projection assembly), GO:0060287 (epithelial cilium movement involved in determination of left/right asymmetry), GO:0060271 (cilium assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0036064 (ciliary basal body), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0005929 (cilium), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015630 (microtubule cytoskeleton)