Protein: Gap junction protein (Q9DF30)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell
Subcellular location: Cell junction, gap junction. Cell membrane; Multi- pass membrane protein. Membrane; Multi-pass membrane protein
InterPro domains:
- IPR000500: Connexin (family) [1-386]
- IPR038359: Connexin, N-terminal domain superfamily (homologous_superfamily) [2-244]
- IPR013092: Connexin, N-terminal (domain) [3-234]
- IPR019570: Connexin, cysteine-rich domain (domain) [167-233]
- IPR017990: Connexin, conserved site (conserved_site) [54-205]
Sequence:
MGDWNFLGGILEEVHIHSTMVGKIWLTILFIFRMLVLGVAAEDVWNDEQADFICNTEQPGCRNVCYDKAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRALEKERQRKKMALRRELEGVDVEMAEVRRKIERELRQIDQGKLNKAPLRGSLLRTYVAHIVTRSAVEVFFMTGQYVLYGFQLNTLYKCEREPCPNAVDCFVSRPTEKSVFMVFMQCIAGISLFLNILEILHLGYKKLKKVILNYYAQLRDDPNDSYYPNKVKKDSVVHQTCIGTSTGRKATIASAPSGYNLHLDRPPDGAAYPPLINPSSAFLPVQGDLPAKNGADEPKYLQNSPTEHNSNSNNTSSDSHSPPCNSVTPPKQDEGEDSVQTLPLHKKGQESKLSESSSHTRESSHASSSMVKKPWKGSAPWNCSTVVEGNGSDSDSLEGSKARCPYSAVRARTSSRSDTKLSRPTSPDSVEESSSESRHSPRASPSHRASLASSSSSRRAAPTDLQI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015267 (channel activity), GO:0022829 (wide pore channel activity), GO:0005243 (gap junction channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048589 (developmental growth), GO:0048856 (anatomical structure development), GO:0048869 (cellular developmental process), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0035265 (organ growth), GO:0008283 (cell population proliferation), GO:0007154 (cell communication), GO:0098868 (bone growth), GO:0035295 (tube development), GO:0048736 (appendage development), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0070121 (Kupffer's vesicle development), GO:0009790 (embryo development), GO:0035107 (appendage morphogenesis), GO:0042246 (tissue regeneration), GO:0031099 (regeneration), GO:0030097 (hemopoiesis), GO:0033334 (fin morphogenesis), GO:0048705 (skeletal system morphogenesis), GO:0048568 (embryonic organ development), GO:0060348 (bone development), GO:0001501 (skeletal system development), GO:0035050 (embryonic heart tube development), GO:0048562 (embryonic organ morphogenesis), GO:0072359 (circulatory system development), GO:0060349 (bone morphogenesis), GO:0033333 (fin development), GO:0060429 (epithelium development), GO:0007507 (heart development), GO:0009792 (embryo development ending in birth or egg hatching), GO:0031101 (fin regeneration), GO:0043009 (chordate embryonic development), GO:0048704 (embryonic skeletal system morphogenesis), GO:0035162 (embryonic hemopoiesis), GO:0048706 (embryonic skeletal system development), GO:0072498 (embryonic skeletal joint development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction), GO:0070161 (anchoring junction), GO:0005911 (cell-cell junction), GO:0005921 (gap junction)