Protein: Frizzled-3 isoform X1 (A0A8M2B7P5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
- IPR041769: Frizzled 3, cysteine-rich domain (domain) [26-152]
- IPR017981: GPCR, family 2-like, 7TM (domain) [201-508]
- IPR015526: Frizzled/secreted frizzled-related protein (family) [28-510]
- IPR036790: Frizzled cysteine-rich domain superfamily (homologous_superfamily) [22-144]
- IPR000539: Frizzled/Smoothened, 7TM (domain) [194-519]
- IPR020067: Frizzled domain (domain) [25-140]
Sequence:
MVLLWALCSMLTVCMAINMEATGSHSMFSCEPITLRMCQGLAYNTTFMPNLLNHYDQQTAALAMEPFHPMVNLECSTEIRPFLCALYAPVCTEYGRVTLPCRRLCQRAKSDCYKLMEMFGVSWPDEMECSRFPECEESYPRAIDLLPSSDSTEESPSAVQRDYGFWCPRELKIEPDLGYSFMGVRDCSPPCPNMYFRKDELIFARYFIGVISIVCLSATLFTFLTFLIDVGRFRYPERPIIFYAVCYMMVSLVFFLGFLLEDRVSCNTASPGRFRASTITQGSHNKACTLLFMTLYFFTMAGSVWWVILTITWFLAAVPKWGSEAIEKKALLFHAVAWGVPGALTITLMAMNKIEGDSMSGVCFVGLYDLMALRWFLLVPLVLDVIVGVVLLLAGIAALNRVRMEIPLEKENQDKLVKFMIRIGVFSVLYLVPLLTVIGCYLYEQSHRSVWETTWVQERCREYHIPCPFKVEKTSRPDIALFLIKYLMMLVVGIPSVFWVGSKKTCFEWASFFSGHRRKDSAVHESRQVLQEPDFTQLLLRDPNTPVVRKSRGTSTQGTSTHASSTHLAMLDEPPSASTSRAGSTRSKSSSFHGSLHRSRDGRYTASSFRGVEERVSHGSSLRLNEPLQHCAINRLDSQSRHGSLQRLESQSRHSSVRDLSITAQAIQSSPGNGIHRVMEEDATKA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0042813 (Wnt receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0032501 (multicellular organismal process), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0042221 (response to chemical), GO:0042330 (taxis), GO:0071840 (cellular component organization or biogenesis), GO:0032989 (cellular component morphogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0021548 (pons development), GO:0030902 (hindbrain development), GO:0048857 (neural nucleus development), GO:0022037 (metencephalon development), GO:0000902 (cell morphogenesis), GO:0060322 (head development), GO:0016043 (cellular component organization), GO:0006935 (chemotaxis), GO:0030030 (cell projection organization), GO:0097485 (neuron projection guidance), GO:0032990 (cell part morphogenesis), GO:0048666 (neuron development), GO:0007420 (brain development), GO:0022008 (neurogenesis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0007399 (nervous system development), GO:0007417 (central nervous system development), GO:0048858 (cell projection morphogenesis), GO:0030182 (neuron differentiation), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0007411 (axon guidance), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0033564 (anterior/posterior axon guidance), GO:0048812 (neuron projection morphogenesis), GO:0061564 (axon development), GO:0071679 (commissural neuron axon guidance), GO:0007409 (axonogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)