Protein: Pyridoxine-5'-phosphate oxidase (Q91XF0)
Organism: Mus musculus (Mouse)
Function: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
InterPro domains:
- IPR019740: Pyridoxamine 5'-phosphate oxidase, conserved site (conserved_site) [216-229]
- IPR000659: Pyridoxamine 5'-phosphate oxidase (family) [32-261]
- IPR012349: FMN-binding split barrel (homologous_superfamily) [51-261]
- IPR019576: Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal (domain) [206-261]
- IPR011576: Pyridoxamine 5'-phosphate oxidase, N-terminal (domain) [75-193]
Sequence:
MTCGLLSVTVTFRRPAKWTGYLRHLCCRGAVMDLGPMRKSYRGDREAFEETHLTSLDPMKQFASWFDEAVQCPDIGEANAMCVATCTRDGKPSARMLLLKGFGKDGFRFFTNYESRKGKELDSNPFASLVFYWEPLNRQVRVEGPVKKLPEKEAENYFHSRPKSSQIGAVVSRQSSVIPDREYLRKKNEELGQLYQDQEVPKPEYWGGYILYPQVMEFWQGQTNRLHDRIVFRRGLATGDSPLGPMTHHGEEDWVYERLAP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016638 (oxidoreductase activity, acting on the CH-NH2 group of donors), GO:0016641 (oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009058 (biosynthetic process), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0009791 (post-embryonic development), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:1901615 (organic hydroxy compound metabolic process), GO:0002165 (instar larval or pupal development), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0019637 (organophosphate metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006766 (vitamin metabolic process), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0006081 (cellular aldehyde metabolic process), GO:0006793 (phosphorus metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0002164 (larval development), GO:0080090 (regulation of primary metabolic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0009110 (vitamin biosynthetic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0019438 (aromatic compound biosynthetic process), GO:1901617 (organic hydroxy compound biosynthetic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0042822 (pyridoxal phosphate metabolic process), GO:0010468 (regulation of gene expression), GO:1901566 (organonitrogen compound biosynthetic process), GO:0046184 (aldehyde biosynthetic process), GO:0006767 (water-soluble vitamin metabolic process), GO:0018130 (heterocycle biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0090407 (organophosphate biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0051252 (regulation of RNA metabolic process), GO:0072524 (pyridine-containing compound metabolic process), GO:0002168 (instar larval development), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0042364 (water-soluble vitamin biosynthetic process), GO:0042816 (vitamin B6 metabolic process), GO:0042823 (pyridoxal phosphate biosynthetic process), GO:0072525 (pyridine-containing compound biosynthetic process), GO:0006357 (regulation of transcription by RNA polymerase II), GO:0042819 (vitamin B6 biosynthetic process), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)