Protein: Serine protease hepsin isoform X1 (A0A8M9PJK7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR043504: Peptidase S1, PA clan, chymotrypsin-like fold (homologous_superfamily) [145-396]
- IPR009003: Peptidase S1, PA clan (homologous_superfamily) [136-395]
- IPR033116: Serine proteases, trypsin family, serine active site (active_site) [338-349]
- IPR001254: Serine proteases, trypsin domain (domain) [151-396]
- IPR015352: Hepsin, SRCR domain (domain) [42-148]
- IPR001190: SRCR domain (domain) [34-140]
- IPR001314: Peptidase S1A, chymotrypsin family (family) [178-349]
- IPR018114: Serine proteases, trypsin family, histidine active site (active_site) [188-193]
- IPR036772: SRCR-like domain superfamily (homologous_superfamily) [37-146]
Sequence:
MSIFSPCRVVAAVSLILIILGGLGAAIWALVTYLRTTEDTGLFDVQVSAADQRLRVFDSTQWRWKYVCSSSVNQLIANITCEEMGFVRAVNFSVTCAPESGGDRDFFCVKESELTYGKKIKTALYPCKCDKGQILEVICQDCGRRMLPEERIVGGVDARQGSWPWQVSLQYDGVHQCGGSIISDRWIISAAHCFPERYRHASRWRVLMGSIYNTPIRKNVVIAEVKTVVYHSSYLPFVDANIDDNSRDIAVISLTKPLQFTDYIQPVCLPTYGQRLADGQMGTVTGWGNVEYYGTQANVLQEAHVPIISDAVCNGPDYYDNQVTTTMFCAGYEKGGTDSCQGDSGGPFVAADVLSKTSRYRLLGVVSWGTGCAMAKKPGVYTRVSRFLPWISTAMRMYENSPGVHKMARAATP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0017171 (serine hydrolase activity), GO:0008233 (peptidase activity), GO:0008236 (serine-type peptidase activity), GO:0004175 (endopeptidase activity), GO:0004252 (serine-type endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065008 (regulation of biological quality), GO:0019222 (regulation of metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0050817 (coagulation), GO:0065009 (regulation of molecular function), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0050790 (regulation of catalytic activity), GO:0050878 (regulation of body fluid levels), GO:1901564 (organonitrogen compound metabolic process), GO:0007596 (blood coagulation), GO:0009611 (response to wounding), GO:0019538 (protein metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0043170 (macromolecule metabolic process), GO:0042060 (wound healing), GO:0051246 (regulation of protein metabolic process), GO:0051336 (regulation of hydrolase activity), GO:0072378 (blood coagulation, fibrin clot formation), GO:0051604 (protein maturation), GO:0007599 (hemostasis), GO:0010467 (gene expression), GO:0030162 (regulation of proteolysis), GO:0052547 (regulation of peptidase activity), GO:0072376 (protein activation cascade), GO:1902571 (regulation of serine-type peptidase activity), GO:0052548 (regulation of endopeptidase activity), GO:1900003 (regulation of serine-type endopeptidase activity)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)