Protein: Trifunctional purine biosynthetic protein adenosine-3 (A6JLG8)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR016185: Pre-ATP-grasp domain superfamily (homologous_superfamily) [3-105]
- IPR020562: Phosphoribosylglycinamide synthetase, N-terminal (domain) [4-104]
- IPR020559: Phosphoribosylglycinamide synthetase, conserved site (conserved_site) [292-299]
- IPR016188: PurM-like, N-terminal domain (domain) [488-593]
- IPR001555: Phosphoribosylglycinamide formyltransferase, active site (active_site) [940-963]
- IPR037123: Phosphoribosylglycinamide synthetase, C-domain superfamily (homologous_superfamily) [333-432]
- IPR004733: Phosphoribosylformylglycinamidine cyclo-ligase (family) [86-783]
- IPR020560: Phosphoribosylglycinamide synthetase, C-domain (domain) [333-426]
- IPR004607: Phosphoribosylglycinamide formyltransferase (family) [808-996]
- IPR011054: Rudiment single hybrid motif (homologous_superfamily) [332-426]
- IPR036921: PurM-like, N-terminal domain superfamily (homologous_superfamily) [434-598]
- IPR002376: Formyl transferase, N-terminal (domain) [809-988]
- IPR010918: PurM-like, C-terminal domain (domain) [607-774]
- IPR011761: ATP-grasp fold (domain) [111-318]
- IPR000115: Phosphoribosylglycinamide synthetase (family) [3-426]
- IPR020561: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain (domain) [105-298]
- IPR036676: PurM-like, C-terminal domain superfamily (homologous_superfamily) [600-793]
- IPR036477: Formyl transferase, N-terminal domain superfamily (homologous_superfamily) [809-1008]
- IPR013815: ATP-grasp fold, subdomain 1 (homologous_superfamily) [123-193]
Sequence:
MAARVLVIGSGGREHTLAWKLAQSPHVKQVLVAPGNAGTASAGKISNAAVSINDHTALARFCKDEKIELVVVGPEAPLAAGIVGDLTSAGVRCFGPTAQAALLESSKKFAKEFMDRHGVPTAQWRAFTSPEDACSFIMSADFPALVVKASGLAAGKGVIVAKSKAEACEAVQEIMQEKSFGAAGETVVVEELLEGEEVSCLCFTDGKTVAPMPPAQDHKRLLDGDRGPNTGGMGAYCPAPQVPKDLLVKIKNTILQRTVDGMQQEGVPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQVILPLLKSDLYEVIQSTFDGLLSESPPVWLENHSAVTVVMASGGYPGAYTKGVEITGFPEAQALGLQVFHAGTALKDAKVVTSGGRVLTVTAVRENLMSALDEARKGLAALKFEGAVYRKDIGFRAVAFLQRPRGLTYKDSGVDIAAGNMLVKKIQPLAKATSRPGCSVDLGGFAGLFDLKAAGFKDPLLASGTDGVGTKLKIAQLCNKHDSIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLSTTEAVVAGIAAACRQAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERHQKLPQLERIAEGDAVIGVASSGLHSNGFSLVRKIVERSSLQYSSPAPGGCGDQTLGDLLLTPTRIYSHSLLPIIRSGRVKAFAHITGGGLLENIPRVLPRKLGVDLDAYTWRVPKVFSWLQQEGQLSEEEMARTFNCGVGAALVVSKDQTEQILHDIRQHQEDAWVIGSVVECPEDSPRVRVKNLIETMQTKGSVVTNGFLRSNFPSQQKKARVAVLISGTGSNLQALIDSTRDPKSSSHIVLVISNKAAVAGLDRAERAGIPTRVINHKLYKSRVEFDNAVDHVLEEFSVDIVCLAGFMRILSGPFVRKWDGKMLNIHPSLLPSFKGSNAHEQVLEAGVTITGCTVHFVAEDVDAGQIILQEAVPVQRDDTVATLSERVKAAEHKIFPAALQLVASGAVQLGEDGKIHWAREQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016874 (ligase activity), GO:0016740 (transferase activity), GO:0016741 (transferase activity, transferring one-carbon groups), GO:0016879 (ligase activity, forming carbon-nitrogen bonds), GO:0016742 (hydroxymethyl-, formyl- and related transferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0032501 (multicellular organismal process), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009058 (biosynthetic process), GO:0042221 (response to chemical), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0021987 (cerebral cortex development), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0021537 (telencephalon development), GO:0046483 (heterocycle metabolic process), GO:0048731 (system development), GO:0019637 (organophosphate metabolic process), GO:0048513 (animal organ development), GO:0030902 (hindbrain development), GO:0044249 (cellular biosynthetic process), GO:0006520 (amino acid metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006766 (vitamin metabolic process), GO:0022037 (metencephalon development), GO:0010033 (response to organic substance), GO:0006793 (phosphorus metabolic process), GO:0021549 (cerebellum development), GO:0010035 (response to inorganic substance), GO:1901360 (organic cyclic compound metabolic process), GO:0006575 (cellular modified amino acid metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0060322 (head development), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0006082 (organic acid metabolic process), GO:0030900 (forebrain development), GO:0021543 (pallium development), GO:1901362 (organic cyclic compound biosynthetic process), GO:0006753 (nucleoside phosphate metabolic process), GO:0042398 (cellular modified amino acid biosynthetic process), GO:0043436 (oxoacid metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0006760 (folic acid-containing compound metabolic process), GO:0033013 (tetrapyrrole metabolic process), GO:1901605 (alpha-amino acid metabolic process), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0007420 (brain development), GO:0007399 (nervous system development), GO:0006767 (water-soluble vitamin metabolic process), GO:0018130 (heterocycle biosynthetic process), GO:0090407 (organophosphate biosynthetic process), GO:0007417 (central nervous system development), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0042558 (pteridine-containing compound metabolic process), GO:0009235 (cobalamin metabolic process), GO:1901293 (nucleoside phosphate biosynthetic process), GO:0009069 (serine family amino acid metabolic process), GO:0009396 (folic acid-containing compound biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0009123 (nucleoside monophosphate metabolic process), GO:0042559 (pteridine-containing compound biosynthetic process), GO:0046653 (tetrahydrofolate metabolic process), GO:0009124 (nucleoside monophosphate biosynthetic process), GO:0006544 (glycine metabolic process), GO:0009161 (ribonucleoside monophosphate metabolic process), GO:0009156 (ribonucleoside monophosphate biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)