Protein: receptor protein-tyrosine kinase (A6K1A4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Single-pass type I membrane protein
InterPro domains:
- IPR050122: Receptor Tyrosine Kinase (family) [81-905]
- IPR008266: Tyrosine-protein kinase, active site (active_site) [767-779]
- IPR001245: Serine-threonine/tyrosine-protein kinase, catalytic domain (domain) [568-902]
- IPR013151: Immunoglobulin-like beta-sandwich domain (domain) [217-299]
- IPR000719: Protein kinase domain (domain) [568-903]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [34-489]
- IPR001824: Tyrosine-protein kinase, receptor class III, conserved site (conserved_site) [627-640]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [37-291]
- IPR007110: Immunoglobulin-like domain (domain) [211-301]
- IPR017441: Protein kinase, ATP binding site (binding_site) [574-602]
- IPR020635: Tyrosine-protein kinase, catalytic domain (domain) [568-903]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [535-901]
- IPR003599: Immunoglobulin domain subtype (domain) [36-303]
Sequence:
MARRRESHRRTSWFQNPQRTSGVPRSIGVEGVVYEAVTVEVAQSASFTLQVQLTTPGDVSCLWVFKHSSLGCQPHFDLQNRRIVSMTILNVTETQAGEYLLHIQSEATNHTVLFTVNVRDTQLYVLRRPSFRKMENQDALLCVSEGVPEPTVEWVVCSSHRDSCREEGSAVVKKEEKVLHELFETDIRCCARNALGRECTKLFTIDLNQAPQSTLPQLFLKVGEPLWIRCKAIHVNHGFGLTWELGNKVLEEGSYFEMSSYSTNRSMIRILLAFVSSVGRNNTGYYTCSSSKHPSQTALVTILEKGFINATSSQEEYEIDPYEKFCFSVRFKAYPQIRCKWTFSQTSFPCEQSGLEDGYSISKFCDHKNNPGEYIFHGENDDAQFTKMFILNIRRKPQVLANASASQASCFSDGYPLPNWTWKKCSDKSPNCTEEIPEGVWNKKANRKVFGQWVSSSTLNMSEAGRGFLVKCCAYNSMGTSCETILLNSPGPFLFIQDNISFYATIGLCPPFIVVLTVLICHKYKKQFRYESQLQMIQVTGPLDNEYFYIDFRDYEYDLKWEFPRENLEFGKVLGSGAFGRVMNATAYGISKTGVSIQVAVKMLKEKADRCEREALMAELKMMTHLGHHDNIVNLLGACTLSGPVYLIFEYCCHGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHSNSSMPGSREVQIYPPVDQVSGFNGNSIHSEDEIEYENQKRLEEEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDILSDSSYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQSGFKMEQPFYATEEIYFVMQSCWAFDSRKRPSFPNLTSFLGCQLAEAEAAPAIYQNRRPASREAGSEPPSPQVQEKTHRERS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0008134 (transcription factor binding), GO:0140297 (DNA-binding transcription factor binding), GO:0061629 (RNA polymerase II-specific DNA-binding transcription factor binding), GO:0016922 (nuclear receptor binding), GO:0035259 (nuclear glucocorticoid receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0048856 (anatomical structure development), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0071495 (cellular response to endogenous stimulus), GO:1901698 (response to nitrogen compound), GO:0031099 (regeneration), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0009725 (response to hormone), GO:0048513 (animal organ development), GO:0048545 (response to steroid hormone), GO:0031100 (animal organ regeneration), GO:0032870 (cellular response to hormone stimulus), GO:0014070 (response to organic cyclic compound), GO:0010243 (response to organonitrogen compound), GO:0071310 (cellular response to organic substance), GO:0033993 (response to lipid), GO:0031960 (response to corticosteroid), GO:0071383 (cellular response to steroid hormone stimulus), GO:0071407 (cellular response to organic cyclic compound), GO:0071396 (cellular response to lipid), GO:0051384 (response to glucocorticoid), GO:0071384 (cellular response to corticosteroid stimulus), GO:0071385 (cellular response to glucocorticoid stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)