lokahq/bioreason-rl huggingface dataset:
Protein: Similar to CG11030-PA (Predicted) (A6KGY5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell projection, filopodium
InterPro domains:
- IPR007146: Sas10/Utp3/C1D (family) [18-98]
Sequence:
MEAPEVLESEVSSSITLLKNLQEQVMAVTAQVQALTAKVRAGAYSTEKGLSLLEVKDQLLLMYLMDLSHLILDKASGGSLQGHPAVLRLVEIRTVLEKLRPLDQKLKYQIDKLVKTAVTGSLSENDPLRFKPHPSNMMSKLSSEDEEENEAEEDQSEASGKKSVKGASKKYVPPRLVPVHYDETEAEREQKRLEKAKRRALSSSVIRELKEQYSDAPEEIRDVRHPHVTRQSQEDQHRINYEESMMVRLSVSKREKGLRRRASAMSSQLHSLTHFSDISALTGGTAHLDEDQNPVKKRKKMPKKGRKKKGFRRRW
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0045182 (translation regulator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0023051 (regulation of signaling), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0099177 (regulation of trans-synaptic signaling), GO:0080090 (regulation of primary metabolic process), GO:0010646 (regulation of cell communication), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0050804 (modulation of chemical synaptic transmission), GO:0034248 (regulation of amide metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0051246 (regulation of protein metabolic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:0006417 (regulation of translation), GO:0010608 (post-transcriptional regulation of gene expression), GO:0099170 (postsynaptic modulation of chemical synaptic transmission), GO:2000112 (regulation of cellular macromolecule biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction), GO:0098794 (postsynapse), GO:0045202 (synapse), GO:0098978 (glutamatergic synapse)
Protein: Mediator of RNA polymerase II transcription subunit 30 (A6HRF1)
Organism: Rattus norvegicus (Rat)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors
Subcellular location: Nucleus
InterPro domains:
- IPR021019: Mediator complex, subunit Med30, metazoa (family) [9-114]
Sequence:
MSTPPLAPTGMASGPFGGPQAQQAAREVNTATLCRIGQETVQDIVYRTMEIFQLLRNMQLPNGVTYHTGTYQDRLTKLQDHLRQLSILFRKLRLVYDKCNENCGGMDPIPVEKLKQKNQQLKQIMDQLRNLIWDINAMLAMRN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity), GO:0061659 (ubiquitin-like protein ligase activity), GO:0061630 (ubiquitin protein ligase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0070647 (protein modification by small protein conjugation or removal), GO:0032446 (protein modification by small protein conjugation), GO:0016567 (protein ubiquitination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0140535 (intracellular protein-containing complex), GO:1990234 (transferase complex), GO:0000151 (ubiquitin ligase complex)
Protein: C-C motif chemokine (A6I5W4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted
InterPro domains:
- IPR001811: Chemokine interleukin-8-like domain (domain) [28-86]
- IPR036048: Chemokine interleukin-8-like superfamily (homologous_superfamily) [24-94]
- IPR000827: CC chemokine, conserved site (conserved_site) [30-74]
- IPR039809: Chemokine beta/gamma/delta (family) [6-88]
Sequence:
MQQAGLTLVAVAVCVAFRTSEAILPIASSCCTEVSHHIPRRLLERVNSCSIQRADGDCDLAAVILHVKRRRICVSPHNPTLKRWMSASEMKNGKENLCPRKKQDSGKDRKGHTPRKHGKHGTRRIHGTHGHEAPR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (signaling receptor activator activity), GO:0005126 (cytokine receptor binding), GO:0048018 (receptor ligand activity), GO:0001664 (G protein-coupled receptor binding), GO:0005125 (cytokine activity), GO:0042379 (chemokine receptor binding), GO:0008009 (chemokine activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:0007584 (response to nutrient), GO:0009991 (response to extracellular stimulus), GO:0031667 (response to nutrient levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0030141 (secretory granule), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle)
Protein: Tapasin (A6JJI5)
Organism: Rattus norvegicus (Rat)
Function: Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading)
Subcellular location: Membrane; Single- pass type I membrane protein
InterPro domains:
- IPR050380: Immune Recognition and Response Modulators (family) [105-427]
- IPR003597: Immunoglobulin C1-set (domain) [327-409]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [37-418]
- IPR008056: Tapasin (family) [70-429]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [303-421]
- IPR007110: Immunoglobulin-like domain (domain) [309-416]
- IPR003006: Immunoglobulin/major histocompatibility complex, conserved site (conserved_site) [397-403]
Sequence:
MKVKGNRLGRGDRSTMKLLPLLVVVALGLATVVVSAGPQTIECWFVEDAGGGGLSKKPATLLLRHGPRGPPPRPDLDPKLYFKVDDPAGMLLAAFRRYPAGAHAPHCEMSSYIPFPASAKWARGLSPQQNCSRALDGDWLMVSVSGTVFSLSSLLRPLPEPQREPVFITMATVVLTVLTRHPAPRIHLGKDAVLDLRFAYAPPALEDAPSVASGPPPFGLEWRRQHRGKGHLLLAAIPGLLEKMPPAREKAVAFAAWDDDNDPWGPWTGNGTLWLPAVSPSQEGVYLATVHLPYLQGQVSLELTVHKPPRVSLTPAPIVWAAPGEAPPELLCLVSHFYPEEGLEVEWELRGGPEGSSRKAEGKTWVSTVRHHSDGSVSQSGHLQLPPVTDKQHGVRYACRVRHPSLPSSGRSAEVTLEVAGFSGPSIEDGIGLFLSAFLLLGLFKALGWMAAYLTIPKILKEKASATSLTVPKDEKKSE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0043933 (protein-containing complex organization), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0140534 (endoplasmic reticulum protein-containing complex), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0098796 (membrane protein complex), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0031090 (organelle membrane), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098827 (endoplasmic reticulum subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0005789 (endoplasmic reticulum membrane)
Protein: ATP-dependent RNA helicase (A6K809)
Organism: Rattus norvegicus (Rat)
Function: RNA helicase
InterPro domains:
- IPR001650: Helicase, C-terminal domain-like (domain) [352-522]
- IPR044773: DDX18/Has1, DEAD-box helicase domain (domain) [143-340]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [125-571]
- IPR025313: ATP-dependent rRNA helicase SPB4-like, C-terminal extension (domain) [513-576]
- IPR011545: DEAD/DEAH-box helicase domain (domain) [156-327]
- IPR000629: ATP-dependent RNA helicase DEAD-box, conserved site (conserved_site) [284-292]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [151-356]
Sequence:
MSQLQMKLLRKKIEKRNAKLRQRNLKLQEASDRSLSQPENGDVPEELGKGGKAKKALKHSVTAGSAEAQSRGVPEETVENAKVKKSPQKLTILTNGEAAAMPSTDPELKKKKKKKRKIGNDTEPGAFEDTSFASLSNLVNENTLKAIEEMGFKHMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPVIELIVKLKFMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEVQKLLNGINIVVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPARRQTMLFSATQTRKVEDLARISLKKEPLYVGVDDDKEVATVDGLEQGYVVCPSEKRFLLLFTFLKKNRKKKVMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGILLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGFLRYLKQSKVPLNQFDFSWSKVSDIQSQLEKLIEKNYFLHKSAQEAYKSYIRAYDSHSLKQIFNVNNLNLPQVALSFGFKVPPFVDLNVSSHDGKLKKRGGGGGFGYQKTKKVEKSKIFKHISKKPADRRQFSH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:1901700 (response to oxygen-containing compound), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0014070 (response to organic cyclic compound), GO:0032355 (response to estradiol), GO:1901701 (cellular response to oxygen-containing compound), GO:0071310 (cellular response to organic substance), GO:0033993 (response to lipid), GO:0071392 (cellular response to estradiol stimulus), GO:0071407 (cellular response to organic cyclic compound), GO:0071396 (cellular response to lipid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Nucleophosmin/nucleoplasmin 2 (F7FK60)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR004301: Nucleoplasmin family (family) [7-200]
- IPR036824: Nucleoplasmin core domain superfamily (homologous_superfamily) [16-118]
- IPR024057: Nucleoplasmin core domain (domain) [18-117]
Sequence:
MSRHSTSSMTETTAKNMLWGSELTQEKQTCTFRAQGERKDSCKLLLSTICLGEKAKEEVNRVEILPQEDRKSPITVATLKASVLPMVTVTGIELSPPVTFRLRAGSGPVFLSGQECYETSDMAWEDDEEEEEEEEEDEDEDEDADLSLEEIPIKQVKRAAPQRPTSIAKRKKVDKEEEAAVRPSPQDKSPWKKGKSTPKPKRSTSKK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0019899 (enzyme binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0065009 (regulation of molecular function), GO:0048522 (positive regulation of cellular process), GO:0050790 (regulation of catalytic activity), GO:0044093 (positive regulation of molecular function), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051052 (regulation of DNA metabolic process), GO:0051054 (positive regulation of DNA metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0043085 (positive regulation of catalytic activity), GO:0006275 (regulation of DNA replication), GO:0045740 (positive regulation of DNA replication)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Eyes absent homolog (A6JUP2)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR028472: Protein phosphatase EYA (family) [84-559]
- IPR038102: EYA domain superfamily (homologous_superfamily) [346-560]
- IPR042577: EYA domain, metazoan (domain) [345-559]
- IPR006545: EYA domain (domain) [346-559]
Sequence:
MEDTQDLNEQSVKKTCPESDVSEPQNSRSMEMQDLASPHALVGGSDTPGSSKLDKSGLSSTSVTTNGTGVSLLAVKTEPLHSSETTTTTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPAYDLGVMLPAIKTESGLPQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTSSSTSTYQLQESLQGLTSQPGEFDTVQSPSTPIKDLDDRTCRSSGSKSRGRGRKNNPSPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHATASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCVNVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKLF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0048856 (anatomical structure development), GO:0048513 (animal organ development), GO:0048839 (inner ear development), GO:0007423 (sensory organ development), GO:0043583 (ear development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Kruppel-like factor 3 (Basic) (Mapped), isoform CRA_b (A6JDG0)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [273-342]
- IPR013087: Zinc finger C2H2-type (domain) [259-341]
Sequence:
MLMFDPVPVKQEAMDPVTVSYPSNYIESMKPNKYGVIYSTPLPDKFFQTPEGLAHGIQMEPVDLTVNKRGSPPSAAGSPSSLKFPSHRRASPGLSMPSSSPPIKKYSPPSPGVQPFGVPLSMPPVMAAALTRHGIRSPGILPVIQPVVVQPVPFMYTSHLQQPLMVSLSEEMDNSNSGMPVPVIESYEKPILQKKIKIEPGIEPQRTDYYPEEMSPPLMNSVSPPQALLQENHPSVIVQPGKRPLPVESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0071495 (cellular response to endogenous stimulus), GO:1901700 (response to oxygen-containing compound), GO:1901698 (response to nitrogen compound), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0071417 (cellular response to organonitrogen compound), GO:1901652 (response to peptide), GO:1901699 (cellular response to nitrogen compound), GO:0010243 (response to organonitrogen compound), GO:1901701 (cellular response to oxygen-containing compound), GO:0071310 (cellular response to organic substance), GO:1901653 (cellular response to peptide)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Similar to Regulator of G-protein signaling 20 (RGS20) (Regulator of G-protein signaling Z1) (A6JFI9)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR044926: RGS, subdomain 2 (homologous_superfamily) [97-237]
- IPR016137: RGS domain (domain) [113-232]
- IPR036305: RGS domain superfamily (homologous_superfamily) [103-234]
Sequence:
MRTANGGPRAGASPSASPEDPNLPVESEQTEMRMRQMCSGSETQGSVPSQQQGVGGRGSNACCFCWCCCCSCSCLTVRNQEDQRPQRAAHELRTDIPACEESPMPTLEEVCAWAQSFDNLMVTPAGRNAFREFLRTEFSEENMLFWMACEELKREANKSTIEEKARIIYEDYISILSPKEVSLDSRVREVINRNMVDPSQHIFDDAQLQIYTLMHRDSYPRFMNSTVYKDLLKSLAEKAVEA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0008047 (enzyme activator activity), GO:0060589 (nucleoside-triphosphatase regulator activity), GO:0030695 (GTPase regulator activity), GO:0005096 (GTPase activator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:1901698 (response to nitrogen compound), GO:0010033 (response to organic substance), GO:0010243 (response to organonitrogen compound), GO:0014075 (response to amine), GO:0001975 (response to amphetamine)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0098862 (cluster of actin-based cell projections), GO:0031090 (organelle membrane), GO:0005794 (Golgi apparatus), GO:0098857 (membrane microdomain), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005903 (brush border), GO:0043227 (membrane-bounded organelle), GO:0045121 (membrane raft), GO:0030135 (coated vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0031982 (vesicle), GO:0000139 (Golgi membrane), GO:0030136 (clathrin-coated vesicle), GO:0097708 (intracellular vesicle)
Protein: Homeobox protein SIX1 (Q99P83)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm. Nucleus
InterPro domains:
- IPR008422: KN homeodomain (domain) [139-172]
- IPR017970: Homeobox, conserved site (conserved_site) [151-174]
- IPR031701: Homeobox protein SIX1, N-terminal SD domain (domain) [3-113]
- IPR001356: Homeodomain (domain) [116-180]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [116-187]
Sequence:
FGFTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHPKLQQLWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRGVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENTENNNSSSNKQNQLSPLEGGKPLMSSSEEEFSPPQSPDQNSVLLLQSNMGHARSSNYSLPGLTASQPSHGLQAHQHQLQDSLLGPLTSS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008134 (transcription factor binding), GO:0001221 (transcription coregulator binding), GO:0001223 (transcription coactivator binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0001101 (response to acid chemical), GO:0071495 (cellular response to endogenous stimulus), GO:1901700 (response to oxygen-containing compound), GO:1901698 (response to nitrogen compound), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:1902074 (response to salt), GO:0071417 (cellular response to organonitrogen compound), GO:1901699 (cellular response to nitrogen compound), GO:0071229 (cellular response to acid chemical), GO:0043200 (response to amino acid), GO:0014070 (response to organic cyclic compound), GO:0010243 (response to organonitrogen compound), GO:0071310 (cellular response to organic substance), GO:1901701 (cellular response to oxygen-containing compound), GO:1902075 (cellular response to salt), GO:0071407 (cellular response to organic cyclic compound), GO:0071230 (cellular response to amino acid stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: RCG53488 (A6JRF0)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR035994: Nucleoside phosphorylase superfamily (homologous_superfamily) [9-227]
- IPR010044: Methylthioadenosine phosphorylase (MTAP) (family) [12-223]
- IPR000845: Nucleoside phosphorylase domain (domain) [65-199]
Sequence:
MASGSACTAVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARTSLRPQTFYDGSHCSARGVCHIPMAEPFCPKTREVLIEMAKKLGLRCHSKGTIVTIEGPRFSSRAESFIFRTWGADVINMTTVPEVVLAKEAGLCYASIAMATDYDCWKEHEEAVSVDGVLKTMKENANKAKSLLLTTIPQIGSMEWSETLRNLKNMAQSSVLPPRH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016763 (pentosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:1901700 (response to oxygen-containing compound), GO:0033993 (response to lipid), GO:0014070 (response to organic cyclic compound), GO:1901654 (response to ketone), GO:0033574 (response to testosterone)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)