Protein: Mitochondrial Rho GTPase (A0A8M2BDN6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Mitochondrial GTPase involved in mitochondrial trafficking
Subcellular location: Membrane; Single- pass type IV membrane protein. Mitochondrion outer membrane; Single-pass type IV membrane protein
InterPro domains:
- IPR001806: Small GTPase (family) [1-187]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [197-328]
- IPR011992: EF-hand domain pair (homologous_superfamily) [168-367]
- IPR020860: MIRO domain (domain) [2-579]
- IPR013567: EF hand associated, type-2 (domain) [218-303]
- IPR021181: Mitochondrial Rho GTPase (family) [1-658]
- IPR005225: Small GTP-binding domain (domain) [3-162]
- IPR002048: EF-hand domain (domain) [188-338]
- IPR052266: Mitochondrial Rho GTPase/EF-hand domain-containing protein (family) [136-440]
- IPR013566: Mitochondrial Rho GTPase 1/3, EF hand associated, type-1 (domain) [340-412]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [2-585]
Sequence:
MRKDVRILLVGEPKVGKTSLIMSLVSEEFPAVVPYRAEEITIPADVTPERVPTHIVDYSEAEQTDEQLFQEISKANVICIVYSVNNQKSIEKVTSHWIPLINERTDKDSRVPLILVGNKSDLVEHSSMETVLPIMNKYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEKKEMRTACVLALTRIFKVSDSDNDGVLNDNELTFFQTCFNTPLAPQALEDVKNVVRKNISDGVHDNGLTLKGFLFLHTLFIQRGRHETTWAVLRRFGYDDDLELHQDYLFPPLKIPPDSTTELNHDAYLFLQSVFDKHDKDRDGSLSPGELIDLFDVFPYVPWGLDVNSTVCTNDQGWITYQGYLSQWTLTTYLDVQRCLEYLGYLGYSIIAEQESQASAITVTRDKKLDLQKKQTQRNVFRCHVFGITGSGKTGFLQGFLGRNLVHQRAIREEHKSYYAISTAHVYGQEKYLLLHKVFPDFDFLSEMELTCDVACLIYDVSNPCSFEYCAQIFKQYFMDSKTPCMLIAAKSDLPETKQQYGMTPLEFCRKHKMPPPQSYTCNTAGAPSKDIFIKLATMAVYPHARLRCMCTCNRCTFCLCQNFLNSELVQTVRTKLYTVILSRHIIHAELKNSSLWLKASVGATICAVLGFAIYRTLLRNR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0071840 (cellular component organization or biogenesis), GO:0032989 (cellular component morphogenesis), GO:0061061 (muscle structure development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0016043 (cellular component organization), GO:0022008 (neurogenesis), GO:0007399 (nervous system development), GO:0042692 (muscle cell differentiation), GO:0055001 (muscle cell development), GO:0032990 (cell part morphogenesis), GO:0007417 (central nervous system development), GO:0006996 (organelle organization), GO:0048858 (cell projection morphogenesis), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0007005 (mitochondrion organization), GO:0070584 (mitochondrion morphogenesis), GO:0048699 (generation of neurons), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0048812 (neuron projection morphogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)