Protein: Carbamyl phosphatate synthetase 2 (Mapped), isoform CRA_c (A6HA84)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR016185: Pre-ATP-grasp domain superfamily (homologous_superfamily) [125-780]
- IPR017926: Glutamine amidotransferase (domain) [3-87]
- IPR036914: Methylglyoxal synthase-like domain superfamily (homologous_superfamily) [1042-1091]
- IPR058047: Carbamoyl phosphate synthase, preATP-grasp domain (domain) [126-775]
- IPR005480: Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (domain) [530-653]
- IPR006275: Carbamoyl-phosphate synthase, large subunit (family) [125-1090]
- IPR011607: Methylglyoxal synthase-like domain (domain) [1040-1093]
- IPR013815: ATP-grasp fold, subdomain 1 (homologous_superfamily) [792-861]
- IPR005483: Carbamoyl phosphate synthase, CPSase domain (domain) [137-511]
- IPR029062: Class I glutamine amidotransferase-like (homologous_superfamily) [1-92]
- IPR036897: Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily (homologous_superfamily) [509-660]
- IPR005479: Carbamoyl phosphate synthase, ATP-binding domain (domain) [246-980]
- IPR011761: ATP-grasp fold (domain) [251-975]
Sequence:
MRYGNRGHNQPCLLVGTGRCFLTSQNHGFAVDADSLPAGWAPLFTNANDCSNEGIVHDNLPFFSVQFHPEHRAGPSDMELLFDVFLETVRDTVAGNAEGRTVRERLAQRLCPPELPIPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGILLTFGGQTALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGFASTKEELSALVAPAFAHTSQVLIDKSLKGWKEIEYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRRTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRNSVTGGTAAFEPSLDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKALRMVDENCVGFDHTVKPVSDVELETPTDKRIFVVAAALWAGYSVERLYELTRIDCWFLHRMKRIVTHAKLLEQHRGRPLPQDLLHQAKCLGFSDKQIALAVLSTELVVRKLRQELGICPAVKQIDTVAAEWPAQTNYLYLTYWGNTHDLDFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQQLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLPNNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQTVGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAVACDGIVSAIAISEHVENAGVHSGDATLVTPPQDITPKTLERIKAIVHAVGQELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRIIMGEKVESVGLMTGSGVVGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIGSYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKPLL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016874 (ligase activity), GO:0016740 (transferase activity), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0016741 (transferase activity, transferring one-carbon groups), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0042802 (identical protein binding), GO:0016879 (ligase activity, forming carbon-nitrogen bonds), GO:0016884 (carbon-nitrogen ligase activity, with glutamine as amido-N-donor), GO:0016812 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides), GO:0016743 (carboxyl- or carbamoyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009058 (biosynthetic process), GO:0042221 (response to chemical), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0044238 (primary metabolic process), GO:0001101 (response to acid chemical), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0009410 (response to xenobiotic stimulus), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009636 (response to toxic substance), GO:0071495 (cellular response to endogenous stimulus), GO:0044249 (cellular biosynthetic process), GO:1901700 (response to oxygen-containing compound), GO:0006520 (amino acid metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0009991 (response to extracellular stimulus), GO:0061061 (muscle structure development), GO:0010035 (response to inorganic substance), GO:0006575 (cellular modified amino acid metabolic process), GO:0007584 (response to nutrient), GO:1901698 (response to nitrogen compound), GO:0009888 (tissue development), GO:0070887 (cellular response to chemical stimulus), GO:0006082 (organic acid metabolic process), GO:0031668 (cellular response to extracellular stimulus), GO:0043603 (amide metabolic process), GO:0071941 (nitrogen cycle metabolic process), GO:0071496 (cellular response to external stimulus), GO:1902074 (response to salt), GO:0010038 (response to metal ion), GO:1901652 (response to peptide), GO:0071417 (cellular response to organonitrogen compound), GO:0071229 (cellular response to acid chemical), GO:0043200 (response to amino acid), GO:1901654 (response to ketone), GO:0055123 (digestive system development), GO:0032355 (response to estradiol), GO:0008652 (amino acid biosynthetic process), GO:0043436 (oxoacid metabolic process), GO:0048732 (gland development), GO:0048545 (response to steroid hormone), GO:1901699 (cellular response to nitrogen compound), GO:0043604 (amide biosynthetic process), GO:0033273 (response to vitamin), GO:0061008 (hepaticobiliary system development), GO:1901605 (alpha-amino acid metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0000050 (urea cycle), GO:0043434 (response to peptide hormone), GO:0000050 (urea cycle), GO:0032870 (cellular response to hormone stimulus), GO:0010243 (response to organonitrogen compound), GO:0033993 (response to lipid), GO:0031667 (response to nutrient levels), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0014070 (response to organic cyclic compound), GO:0007517 (muscle organ development), GO:1901701 (cellular response to oxygen-containing compound), GO:0048565 (digestive tract development), GO:0060541 (respiratory system development), GO:0033762 (response to glucagon), GO:0071548 (response to dexamethasone), GO:0007494 (midgut development), GO:0071375 (cellular response to peptide hormone stimulus), GO:0060538 (skeletal muscle organ development), GO:0031960 (response to corticosteroid), GO:0014075 (response to amine), GO:0070365 (hepatocyte differentiation), GO:0014075 (response to amine), GO:0019752 (carboxylic acid metabolic process), GO:1901653 (cellular response to peptide), GO:0010043 (response to zinc ion), GO:0001889 (liver development), GO:0014074 (response to purine-containing compound), GO:0044344 (cellular response to fibroblast growth factor stimulus), GO:0051412 (response to corticosterone), GO:0032869 (cellular response to insulin stimulus), GO:0051384 (response to glucocorticoid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)