Protein: Gamma-tubulin complex component 4 homolog (Q9VKU7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
InterPro domains:
- IPR042241: Gamma-tubulin complex component, C-terminal domain superfamily (homologous_superfamily) [343-641]
- IPR007259: Gamma-tubulin complex component protein (family) [1-643]
- IPR040457: Gamma tubulin complex component, C-terminal (domain) [345-642]
- IPR041470: Gamma tubulin complex component protein, N-terminal (domain) [2-340]
Sequence:
MIHDLLLACRSHNPEQLGIKAFNETTVIDQFIHPCEREIFMDIIKIIKVYQEVEQFTHSSGRKSDTHGELPDSLHGYYLLNLAKGIEMALEEYYAEIGRLEKYCLGNERNSLSYVYNALYAKFPLLVFMRNLITEIHVLNLRGCVLLHNLHQQCEHGDIQLEKAIKIIMKPVKNAFFSSLAHWLLFGVIDDVHSEFFIKFTPTDAVDGSSFSKSATCSLLSAEKNPEDYIWQYEVNMSQLPGFFSIVLAEKVLFVGQTVLVFKMGRNVKVKNKTDPLAAKLAELDSDDIYQLWSGRESEFFKMVVDLSNEDTINVFRLEKVIIDIKNYVSARLSEIAVNEVDLERQMGLIKDFFLLGRGEFYLEFCSQMVGTMETYREERFKNVTRSFELAATVTGITDDLDKFSLICQRSTSEPDDTSDFNFLQGLSLKYEYEWPLNLLFSPTTIERYNNIFRFLLIIRTYQYEIQRVWAKQTWRAKSAKDVPPNNKIITLRNYLMFFLNNMQYYIQVDVLESQFGILMNVIKSRSDFEVIQRAHTVFLANVLSHCFLLNESETQLNVTGSQNRNPIYGTLLKLFGICEKFAHMTQTKDPSDDLEDEVDQLNESFGVQIASLIQLLVDVKSASCLGPLSQLLLRLDFNCWFSASHNTSA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0015631 (tubulin binding), GO:0043015 (gamma-tubulin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0022414 (reproductive process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0051641 (cellular localization), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0051321 (meiotic cell cycle), GO:0022402 (cell cycle process), GO:0007389 (pattern specification process), GO:0007049 (cell cycle), GO:0051301 (cell division), GO:0071840 (cellular component organization or biogenesis), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0033036 (macromolecule localization), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0021700 (developmental maturation), GO:1903046 (meiotic cell cycle process), GO:0007017 (microtubule-based process), GO:0048609 (multicellular organismal reproductive process), GO:0007276 (gamete generation), GO:0007281 (germ cell development), GO:0000910 (cytokinesis), GO:0007309 (oocyte axis specification), GO:0009798 (axis specification), GO:0044085 (cellular component biogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0007051 (spindle organization), GO:0060810 (intracellular mRNA localization involved in pattern specification process), GO:0007308 (oocyte construction), GO:0045132 (meiotic chromosome segregation), GO:0000226 (microtubule cytoskeleton organization), GO:0009880 (embryonic pattern specification), GO:0071695 (anatomical structure maturation), GO:0007112 (male meiosis cytokinesis), GO:0007059 (chromosome segregation), GO:0061983 (meiosis II cell cycle process), GO:0140013 (meiotic nuclear division), GO:0003002 (regionalization), GO:0006403 (RNA localization), GO:0048469 (cell maturation), GO:0070727 (cellular macromolecule localization), GO:0009790 (embryo development), GO:0016043 (cellular component organization), GO:0000212 (meiotic spindle organization), GO:0009994 (oocyte differentiation), GO:0007143 (female meiotic nuclear division), GO:0007056 (spindle assembly involved in female meiosis), GO:0033206 (meiotic cytokinesis), GO:0000278 (mitotic cell cycle), GO:0007140 (male meiotic nuclear division), GO:0035282 (segmentation), GO:0098813 (nuclear chromosome segregation), GO:0007314 (oocyte anterior/posterior axis specification), GO:0007147 (female meiosis II), GO:0008298 (intracellular mRNA localization), GO:0048477 (oogenesis), GO:0007135 (meiosis II), GO:0060811 (intracellular mRNA localization involved in anterior/posterior axis specification), GO:0007350 (blastoderm segmentation), GO:0009948 (anterior/posterior axis specification), GO:0022607 (cellular component assembly), GO:0090306 (meiotic spindle assembly), GO:0051225 (spindle assembly), GO:0061640 (cytoskeleton-dependent cytokinesis), GO:0007292 (female gamete generation), GO:0048599 (oocyte development), GO:0000578 (embryonic axis specification), GO:0006996 (organelle organization), GO:0048232 (male gamete generation), GO:0007351 (tripartite regional subdivision), GO:0009952 (anterior/posterior pattern specification), GO:0070925 (organelle assembly), GO:0048285 (organelle fission), GO:0007010 (cytoskeleton organization), GO:0008595 (anterior/posterior axis specification, embryo), GO:0000280 (nuclear division), GO:0008358 (maternal determination of anterior/posterior axis, embryo), GO:0140694 (non-membrane-bounded organelle assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000930 (gamma-tubulin complex), GO:0005813 (centrosome), GO:0043229 (intracellular organelle), GO:0000931 (gamma-tubulin ring complex), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015630 (microtubule cytoskeleton)