Protein: Vascular endothelial growth factor C isoform X1 (A0A8M2B6U8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted
InterPro domains:
- IPR050507: Platelet-derived/Vascular endothelial growth factor (family) [33-320]
- IPR023581: Platelet-derived growth factor, conserved site (conserved_site) [140-152]
- IPR004153: CXCXC repeat (repeat) [262-297]
- IPR029034: Cystine-knot cytokine (homologous_superfamily) [40-205]
- IPR000072: PDGF/VEGF domain (domain) [104-202]
Sequence:
MHLFGFSVFCLALFYANLAFESSHDYYEYDQDQADAMEHSEPDLVEQLRSAGSVDELMRIVYPTYRIMLKCRSKMGSRLLRREPSSTETRSEEASFAAAFINLELLKSIEIEWRKTLCMPRQVCLDVGKEFGATNTFYKPPCVSVYRCGGCCNSEELQCRNISTSYISKTLFEITVPVKQGTKPVTISFANHTSCSCLSKQNLYRQQHSIIRRALTECHVANKTCPKNHSWSNHLCKCVLLPDTLHSKPHSDFETDFCGPDKELDEETCQCECRKELRKAGCGPHHYLDKNTCQCVCKAQPSSCGPQQSFNRDTCQCTCAKVCPRSQPLNRTKCVCECTESPNKCFLKGRRFHPATCSCVRPPCNVDPKRRKCKENEYFSEELCHCIPTYWGRLD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0005126 (cytokine receptor binding), GO:0070851 (growth factor receptor binding), GO:0005172 (vascular endothelial growth factor receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0042221 (response to chemical), GO:0090130 (tissue migration), GO:0042330 (taxis), GO:0071840 (cellular component organization or biogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0001763 (morphogenesis of a branching structure), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0048522 (positive regulation of cellular process), GO:0090287 (regulation of cellular response to growth factor stimulus), GO:0032989 (cellular component morphogenesis), GO:0048729 (tissue morphogenesis), GO:0001568 (blood vessel development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0070848 (response to growth factor), GO:0009966 (regulation of signal transduction), GO:0090132 (epithelium migration), GO:0071495 (cellular response to endogenous stimulus), GO:0061138 (morphogenesis of a branching epithelium), GO:0001945 (lymph vessel development), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0000902 (cell morphogenesis), GO:0042127 (regulation of cell population proliferation), GO:0009888 (tissue development), GO:0036303 (lymph vessel morphogenesis), GO:0010646 (regulation of cell communication), GO:0007166 (cell surface receptor signaling pathway), GO:0016043 (cellular component organization), GO:0006935 (chemotaxis), GO:0001946 (lymphangiogenesis), GO:0008284 (positive regulation of cell population proliferation), GO:0016477 (cell migration), GO:0035239 (tube morphogenesis), GO:0007492 (endoderm development), GO:0010631 (epithelial cell migration), GO:0060562 (epithelial tube morphogenesis), GO:0030030 (cell projection organization), GO:0007167 (enzyme-linked receptor protein signaling pathway), GO:0001944 (vasculature development), GO:0097485 (neuron projection guidance), GO:0032990 (cell part morphogenesis), GO:0002009 (morphogenesis of an epithelium), GO:0050678 (regulation of epithelial cell proliferation), GO:0001667 (ameboidal-type cell migration), GO:0050679 (positive regulation of epithelial cell proliferation), GO:0048666 (neuron development), GO:1902547 (regulation of cellular response to vascular endothelial growth factor stimulus), GO:0048754 (branching morphogenesis of an epithelial tube), GO:0022008 (neurogenesis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0007399 (nervous system development), GO:0048514 (blood vessel morphogenesis), GO:0072359 (circulatory system development), GO:0001569 (branching involved in blood vessel morphogenesis), GO:0060841 (venous blood vessel development), GO:0060429 (epithelium development), GO:0048858 (cell projection morphogenesis), GO:1900746 (regulation of vascular endothelial growth factor signaling pathway), GO:0002040 (sprouting angiogenesis), GO:0030182 (neuron differentiation), GO:0071363 (cellular response to growth factor stimulus), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0001938 (positive regulation of endothelial cell proliferation), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0043542 (endothelial cell migration), GO:0007411 (axon guidance), GO:0031175 (neuron projection development), GO:0007169 (transmembrane receptor protein tyrosine kinase signaling pathway), GO:0001936 (regulation of endothelial cell proliferation), GO:0048699 (generation of neurons), GO:0035924 (cellular response to vascular endothelial growth factor stimulus), GO:0038084 (vascular endothelial growth factor signaling pathway), GO:0048812 (neuron projection morphogenesis), GO:0048010 (vascular endothelial growth factor receptor signaling pathway), GO:0061564 (axon development), GO:0008045 (motor neuron axon guidance), GO:0043534 (blood vessel endothelial cell migration), GO:0007409 (axonogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)