Protein: RCG20122 (A6JGM7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Single- pass type I membrane protein
InterPro domains:
- IPR017241: Toll-like receptor (family) [40-852]
- IPR035897: Toll/interleukin-1 receptor homology (TIR) domain superfamily (homologous_superfamily) [702-848]
- IPR003591: Leucine-rich repeat, typical subtype (repeat) [106-583]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [35-652]
- IPR000157: Toll/interleukin-1 receptor homology (TIR) domain (domain) [704-857]
- IPR000483: Cysteine-rich flanking region, C-terminal (domain) [592-643]
- IPR001611: Leucine-rich repeat (repeat) [97-584]
Sequence:
MWCFYSLFSHRIMAYQLDLLIGVVFMASPVLEMSPCFSDGRIALFRGCNLTQIPWVLNTTERLLLSFNYISTVVTTSFPLLEQLLLLELGTQYARLTIGQEAFRNLPNLRILDLGQSQIEVLNPDAFQGLPHLFELRLFDCGLSNAVLRDAYFRNLNSLARLDLSANEIHSLHLHSSFQELSSLSDINFSFNRIFTLCEDELQPLQGRTLSFFGLKSTSLFSRVFVDWEACRNPLRGIRLETLDLSENGWTAAILGNFSHTIQGSHISSLILTYHIMGSGFGFQNIKDPDQSTFASLARSSVLQLDLSHGYIFSLNPRLFETLKDLKKLNLAFNKINKISDYAFHGLDSLQILNLSYNLLGELYNSNFYGLPSIAYLDLQRNHIGIIQDRTFRLLKKLQTLDLRDNALKTIGFIPSVQMVLLGSNKLTHLPHVRFTANFIELSENGLENLSDLYFLLRIPGLQFLILNQNRLSSCSNVDYAPSQNLSLEQLFLAENMLQLAWETGLCWDIFKGLSRLQILYLNNNYLNFLPPGIFNGLVALRMLSLSANRLTMLSPGSLPANLEILDISRNQLFSPDPGLFSSLRALDITHNEFICDCELSTFIVWLNQTNVTLFGSPADVYCMYPNSLLGSSLYNISTKDCDEEEAVRSLNFSLFILCTVTLTLFLVITLIVTKFRGICFLCFKTIQKLMFKGKFRNPEPSAYRYDAYFCFSSKDFEWAQNALLKHLDAQYSSQNRLRLCFEERDFIPGENHISNIQAAVWGSRKTVCLVSRHFLKDGWCLEAFRYAQSRCLSDLKRVLIVVVVGSLPQYQLMRHETIRGFLQKQQYLRWPEDLQDVDWFLDKLSGCILKEEKGKKRSSPIQLRTIRTVS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003725 (double-stranded RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0009607 (response to biotic stimulus), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0051716 (cellular response to stimulus), GO:0003006 (developmental process involved in reproduction), GO:0051707 (response to other organism), GO:0048522 (positive regulation of cellular process), GO:0043207 (response to external biotic stimulus), GO:0031325 (positive regulation of cellular metabolic process), GO:0070887 (cellular response to chemical stimulus), GO:0048731 (system development), GO:0009617 (response to bacterium), GO:0048513 (animal organ development), GO:0009889 (regulation of biosynthetic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0048608 (reproductive structure development), GO:1901700 (response to oxygen-containing compound), GO:0045137 (development of primary sexual characteristics), GO:0007548 (sex differentiation), GO:0046661 (male sex differentiation), GO:0071216 (cellular response to biotic stimulus), GO:0010033 (response to organic substance), GO:0009891 (positive regulation of biosynthetic process), GO:0061458 (reproductive system development), GO:1904407 (positive regulation of nitric oxide metabolic process), GO:0071219 (cellular response to molecule of bacterial origin), GO:0032496 (response to lipopolysaccharide), GO:0080164 (regulation of nitric oxide metabolic process), GO:0071310 (cellular response to organic substance), GO:0033993 (response to lipid), GO:0031326 (regulation of cellular biosynthetic process), GO:0008406 (gonad development), GO:0002237 (response to molecule of bacterial origin), GO:0046546 (development of primary male sexual characteristics), GO:1901701 (cellular response to oxygen-containing compound), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0045429 (positive regulation of nitric oxide biosynthetic process), GO:0071222 (cellular response to lipopolysaccharide), GO:0008584 (male gonad development), GO:0045428 (regulation of nitric oxide biosynthetic process), GO:0071396 (cellular response to lipid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)