Protein: Endonuclease (F7FQ61)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR018524: DNA/RNA non-specific endonuclease, active site (active_site) [135-143]
- IPR040255: Non-specific endonuclease (family) [2-291]
- IPR044929: DNA/RNA non-specific endonuclease superfamily (homologous_superfamily) [55-285]
- IPR001604: DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain (domain) [58-282]
- IPR020821: ENPP1-3/EXOG-like, endonuclease/phosphodiesterase domain (domain) [75-282]
- IPR044925: His-Me finger superfamily (homologous_superfamily) [59-280]
Sequence:
MRALRAGLTLALGAGLGAAAEHWRRREGKGPGLLGRVPVLPVVAADLPALPGGPAGSTGELAKYGLPGVAQLRSRESYVLSYDPRTRGALWVLEQLRPERLRGDGDRRACDFHEDDSVHAYHRATNADYRGSGFDRGHLAAAANHRWSQRAMDDTFYLSNVAPQVPHLNQHAWNNLEKYSRSLTRTYQNVYVCTGPLFLPRTEADGKSYVKYQVIGKNHVAVPTHFFKVLILEAASGQIELRSYVMPNAPVDETLPLERFLVPIESIERASGLLFVPNILARAGNLKAITAGSK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:1901363 (heterocyclic compound binding), GO:0016787 (hydrolase activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0097159 (organic cyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0140097 (catalytic activity, acting on DNA), GO:0004518 (nuclease activity), GO:0003677 (DNA binding), GO:0004536 (deoxyribonuclease activity), GO:0043565 (sequence-specific DNA binding), GO:0004520 (DNA endonuclease activity), GO:0004519 (endonuclease activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0042221 (response to chemical), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0048522 (positive regulation of cellular process), GO:0001666 (response to hypoxia), GO:0010942 (positive regulation of cell death), GO:0010035 (response to inorganic substance), GO:0010941 (regulation of cell death), GO:0006979 (response to oxidative stress), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0070482 (response to oxygen levels), GO:1901700 (response to oxygen-containing compound), GO:0010033 (response to organic substance), GO:0034599 (cellular response to oxidative stress), GO:0071456 (cellular response to hypoxia), GO:0071453 (cellular response to oxygen levels), GO:0043067 (regulation of programmed cell death), GO:0033993 (response to lipid), GO:0043068 (positive regulation of programmed cell death), GO:0062197 (cellular response to chemical stress), GO:0036293 (response to decreased oxygen levels), GO:0042542 (response to hydrogen peroxide), GO:1901701 (cellular response to oxygen-containing compound), GO:0000302 (response to reactive oxygen species), GO:0032526 (response to retinoic acid), GO:0043065 (positive regulation of apoptotic process), GO:0042981 (regulation of apoptotic process), GO:0036294 (cellular response to decreased oxygen levels), GO:0034614 (cellular response to reactive oxygen species), GO:0070301 (cellular response to hydrogen peroxide)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)