Protein: Periostin, osteoblast specific factor (Predicted), isoform CRA_a (A6JVB5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted, extracellular space, extracellular matrix
InterPro domains:
- IPR000782: FAS1 domain (domain) [99-633]
- IPR050904: Cell adhesion and biosynthesis-related protein (family) [3-595]
- IPR011489: EMI domain (domain) [42-96]
- IPR036378: FAS1 domain superfamily (homologous_superfamily) [72-633]
- IPR016666: TGF beta-induced protein/periostin (family) [1-787]
Sequence:
MVPLLPLSALLLLFLCDVDPANANSYYDKVLAHSRIRGRDQGPNVCALQQILGTKKKYFSSCKNWYQGAICGKKTTVLYECCPGYMRMEGMKGCPAVMPIDHVYGTLGIVGATTTQHYSDVSKLREEIEGKGSYTYFAPSNEAWDNLDSDIRRGLENNVNVELLNALHSHMVNKRMLTKDLKHGMVIPSMYNNLGLFINHYPNGVVTVNCARVIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDELSSFRAAAITSDLLESLGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSEAITGGAVFETMEGNTIEIGCEGDSISINGIKMVNKKDIVTKNGVIHLIDEVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASSLKPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLSDLYNGQILETIGGKQLRVFVYRTAICIENSCMVRGSKQGRNGAIHIFREIIQPAEKSLHEKLRQDKRFSIFLSLLEAADLKDLLTQPGDWTLFAPTNDAFKGMTNEEREILIGDKNALQNIILYHLTPGVYIGKGFEPGVTNILKTTQGSKIYVKGVNETLLVNELKSKESDIMTTNGVIHVVDKLLYPADIPVGNDQLLELLNKLIKYIQIKFVRGSTFKEIPMTVYTTKIITKLVEPKIKVIQGSLQPIIKTEGPAMTKIHIEGEPDFRLIKEGETVTEVIHGEPVIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLQKFLQKDTPAKKIQANKRVQGSRRRSREGRSQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0040007 (growth), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0009605 (response to external stimulus), GO:0048589 (developmental growth), GO:0048869 (cellular developmental process), GO:0009628 (response to abiotic stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0051240 (positive regulation of multicellular organismal process), GO:0071840 (cellular component organization or biogenesis), GO:0051239 (regulation of multicellular organismal process), GO:0014823 (response to activity), GO:0003008 (system process), GO:0065008 (regulation of biological quality), GO:0016049 (cell growth), GO:0009719 (response to endogenous stimulus), GO:0040017 (positive regulation of locomotion), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0048523 (negative regulation of cellular process), GO:0040012 (regulation of locomotion), GO:0048522 (positive regulation of cellular process), GO:0032989 (cellular component morphogenesis), GO:0001666 (response to hypoxia), GO:2000145 (regulation of cell motility), GO:0009611 (response to wounding), GO:0048468 (cell development), GO:0060560 (developmental growth involved in morphogenesis), GO:0030154 (cell differentiation), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0048731 (system development), GO:0070482 (response to oxygen levels), GO:0070848 (response to growth factor), GO:0030155 (regulation of cell adhesion), GO:0071495 (cellular response to endogenous stimulus), GO:0060255 (regulation of macromolecule metabolic process), GO:0008217 (regulation of blood pressure), GO:1901700 (response to oxygen-containing compound), GO:0001817 (regulation of cytokine production), GO:0003013 (circulatory system process), GO:0010033 (response to organic substance), GO:2000147 (positive regulation of cell motility), GO:0000902 (cell morphogenesis), GO:0048588 (developmental cell growth), GO:0014850 (response to muscle activity), GO:0007162 (negative regulation of cell adhesion), GO:0070887 (cellular response to chemical stimulus), GO:0016043 (cellular component organization), GO:0001819 (positive regulation of cytokine production), GO:0042246 (tissue regeneration), GO:0009612 (response to mechanical stimulus), GO:0031099 (regeneration), GO:0071559 (response to transforming growth factor beta), GO:0034097 (response to cytokine), GO:0010812 (negative regulation of cell-substrate adhesion), GO:0030030 (cell projection organization), GO:0032355 (response to estradiol), GO:0008015 (blood circulation), GO:0010810 (regulation of cell-substrate adhesion), GO:0071310 (cellular response to organic substance), GO:0032642 (regulation of chemokine production), GO:0032722 (positive regulation of chemokine production), GO:0032990 (cell part morphogenesis), GO:0071774 (response to fibroblast growth factor), GO:0010628 (positive regulation of gene expression), GO:0030334 (regulation of cell migration), GO:0010468 (regulation of gene expression), GO:0048666 (neuron development), GO:0022008 (neurogenesis), GO:0042060 (wound healing), GO:0007399 (nervous system development), GO:0003073 (regulation of systemic arterial blood pressure), GO:0033993 (response to lipid), GO:0036293 (response to decreased oxygen levels), GO:0030335 (positive regulation of cell migration), GO:0014070 (response to organic cyclic compound), GO:0048858 (cell projection morphogenesis), GO:1990138 (neuron projection extension), GO:0030182 (neuron differentiation), GO:0071363 (cellular response to growth factor stimulus), GO:0001953 (negative regulation of cell-matrix adhesion), GO:0071560 (cellular response to transforming growth factor beta stimulus), GO:1900024 (regulation of substrate adhesion-dependent cell spreading), GO:2000343 (positive regulation of chemokine (C-X-C motif) ligand 2 production), GO:0001952 (regulation of cell-matrix adhesion), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0014910 (regulation of smooth muscle cell migration), GO:0071345 (cellular response to cytokine stimulus), GO:2000341 (regulation of chemokine (C-X-C motif) ligand 2 production), GO:0031175 (neuron projection development), GO:0034612 (response to tumor necrosis factor), GO:0048699 (generation of neurons), GO:1900025 (negative regulation of substrate adhesion-dependent cell spreading), GO:0044344 (cellular response to fibroblast growth factor stimulus), GO:0014911 (positive regulation of smooth muscle cell migration), GO:0048812 (neuron projection morphogenesis), GO:0071356 (cellular response to tumor necrosis factor)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:0030054 (cell junction), GO:0005576 (extracellular region), GO:0005615 (extracellular space), GO:0045202 (synapse), GO:0031594 (neuromuscular junction)