Protein: Transforming acidic coiled-coil containing protein 3 (A0A087WUE2)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm
InterPro domains:
- IPR007707: Transforming acidic coiled-coil-containing protein, C-terminal (domain) [279-472]
- IPR039915: TACC family (family) [99-477]
- IPR057663: TACC3, Aurora-A binding region (binding_site) [162-203]
Sequence:
MSLQVLNDKNVSNEKNTENCDFLFSPPEVTGRSSVLRVSQKENVPPKNLAKAMKVTFQTPLRDPQTHRILSPSMASKLEAPFTQDDTLGLENSHPVWTQKEKQLHSASAEDTPVVQLAAETPTAESKERALNSASTSLPTSCPGSEPVPTHQQGQPALELKEESFRDPAEVLGTGAEVDYLEQFGTSSFKESALRKQSLYLKFDPLLRDSPGRPVPVATETSSMHGANETPSGRPREAKLVEFDFLGALDIPVPGPPPGVPAPGGPPLSTGPIVDLLQYSQKDLDAVVKATQEENRELRSRCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQKELSKAEIQKVLKEKDQLTTDLNSMEKSFSDLFKRFEKQKEVIEGYRKNEESLKKCVEDYLARITQEGQRYQALKAHAEEKLQLANEEIAQVRSKAQAEALALQASLRKEQMRIQSLEKTVEQKTKENEELTRICDDLISKMEKI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0022402 (cell cycle process), GO:0050794 (regulation of cellular process), GO:0007049 (cell cycle), GO:0071840 (cellular component organization or biogenesis), GO:0007017 (microtubule-based process), GO:0051726 (regulation of cell cycle), GO:1903047 (mitotic cell cycle process), GO:0044770 (cell cycle phase transition), GO:0016043 (cellular component organization), GO:0000226 (microtubule cytoskeleton organization), GO:0032886 (regulation of microtubule-based process), GO:0051128 (regulation of cellular component organization), GO:0010564 (regulation of cell cycle process), GO:0000278 (mitotic cell cycle), GO:0044784 (metaphase/anaphase transition of cell cycle), GO:1902850 (microtubule cytoskeleton organization involved in mitosis), GO:0044772 (mitotic cell cycle phase transition), GO:0051983 (regulation of chromosome segregation), GO:0070507 (regulation of microtubule cytoskeleton organization), GO:0090224 (regulation of spindle organization), GO:0033043 (regulation of organelle organization), GO:0006996 (organelle organization), GO:0007010 (cytoskeleton organization), GO:0051493 (regulation of cytoskeleton organization), GO:0007091 (metaphase/anaphase transition of mitotic cell cycle), GO:0033045 (regulation of sister chromatid segregation), GO:0060236 (regulation of mitotic spindle organization), GO:0033044 (regulation of chromosome organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0034451 (centriolar satellite), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0005813 (centrosome), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0005819 (spindle), GO:0072686 (mitotic spindle), GO:0015630 (microtubule cytoskeleton)