Protein: Nuclear factor NF-kappa-B p100 subunit isoform X2 (A0A8M2B350)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm. Nucleus
InterPro domains:
- IPR011029: Death-like domain superfamily (homologous_superfamily) [775-861]
- IPR030497: Nuclear factor NF-kappa-B, p100 subunit, RHD domain, N-terminal (domain) [47-232]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [236-351]
- IPR032397: Rel homology dimerisation domain (domain) [240-338]
- IPR037059: Rel homology domain (RHD), DNA-binding domain superfamily (homologous_superfamily) [46-232]
- IPR030492: Rel homology domain, conserved site (conserved_site) [62-68]
- IPR002110: Ankyrin repeat (repeat) [482-692]
- IPR000451: NF-kappa-B/Dorsal (family) [39-885]
- IPR036770: Ankyrin repeat-containing domain superfamily (homologous_superfamily) [476-706]
- IPR011539: Rel homology domain, DNA-binding domain (domain) [44-235]
- IPR014756: Immunoglobulin E-set (homologous_superfamily) [237-366]
- IPR002909: IPT domain (domain) [238-336]
- IPR008967: p53-like transcription factor, DNA-binding domain superfamily (homologous_superfamily) [46-241]
- IPR000488: Death domain (domain) [778-863]
- IPR033926: NFkappaB IPT domain (domain) [239-337]
Sequence:
MDDTHYQIGFVVNEPMTFPSAYDDLPYMPEAFEVKHEPFVQETVDGPYIQIIEEPKQRGFRFRYECEGPSHGGLPGASSERNRRTYPTVKVLNFVGNARVEVQLVTHTDPPRVHAHSLVGRHCNESGVCSVDVGPSDFTAQFSNLGILHVTKRGVVEVLTKRLKEEKRKVKGPGYKFSDAEENALMQEAKELGKNMDLNIVRLKFTAYLQDSNGSYTRALKPVVSNPIYDSKSPNASNLKISRMDKTSGSVLGGEEVFLLCDKVQKDDIDIRFYEEEDEWEALGDFSPTDVHKQYAIVFKTPPYRCTNIDRPVTVFLQLKRKKGGDCSEPKQFTYVPHNQDKEEVQRKRMKALPDHYGGWRGGPQGGAGGFGGPGSGTGGGGGMGGGFPFNPMDNSSFFVGGCGGFGGGAQMSDSPPQTDGANTQSQSNSQIRQQLIQIALHNRANLAAKCNARALLQYSSTGDARPLLALQRHLCGVQDENGDTPLHLAIIHQKTVVAEQLIKALNSSPQQKFFNKLNKLSQAPLHLAVITKQPKLVEMLMKSGADPSLLDREGRTVLHLAAHTGDDVILRLVLSLLGEHHSHLINSADFTGQYPVHLAVKKDGERCLRLLVEAGAKINMPEQKSGCTALHLAVRDNLLKLACNLITELKADVNACTYGGNSPLHLAASQGSPHLCSMLIAAGADKRIENDEPLFLSSSSSDEDEESEKKLSEDMVQQVHCLSISSERGVFNPRKRPAAGHTPFDLAKSQKVRDLLDGRKGPKPNSLSPKRTKISTEEVNQDLDNEVLSKLCGILIHDDVPWRELAEKLGMLTLTHLYQDSASPCQKLLESYQLSGGPVDGLVEALQALGVREGVRLLRDSQPREDKQSSDSTEDSGFGSQSIGEEMANPAVGNH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0042592 (homeostatic process), GO:0032501 (multicellular organismal process), GO:0048878 (chemical homeostasis), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0055088 (lipid homeostasis), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0035239 (tube morphogenesis), GO:0048514 (blood vessel morphogenesis), GO:0055092 (sterol homeostasis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development), GO:0042632 (cholesterol homeostasis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)