Protein: RCG41048, isoform CRA_a (A6K272)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
InterPro domains:
- IPR028745: A-kinase anchor protein 9/Pericentrin (family) [1-3834]
- IPR019528: Pericentrin/AKAP-450 centrosomal targeting domain (domain) [3632-3713]
Sequence:
MEDEERQRKLAAGKAKLARFRQRKAQCDGDIPKKQKKKRTPSSKQDSSLHTDQQSAEICSESSQRADSAGSPDSSSAEKAKHGQVFAADPESEISTTADECSSEINGCNSVTKPGNPTDTLREEDFSIDDSYSEQGAQSSQTCLQMGENELAEKQHEVEELTQELEEMRASFGTEGLKQLQEFEAAIKQRDGIITQLTANLQQARKEKDDTTIEFLELTEQSQKLQIQFQHLQANETLQNSTLSRTATDLLQAKRQIFTLQQQLQDYQKKEEDVQAQISFLQEKIRMLEMEKDRKVESLNTKEIEEKQAIIEELNTRVIEEERKTAELENKVTTADELLGQLQGQVTEKDQEIKSLKLELVNSQQNERKCSEEIKELMRTVEELQKRNLKDSQLGTGTVRRVEQETQRKLSLLQAELDEMYGKQIVQMKQELMKQHMSQIEELKSQHKRDLENTLKSDASTTVSKEQVNLMSAAISELNVRLQDTHAQKEKLKGELGAALGEKSALQSQFEDLLEEVRFLREQVQKARQTIAEQENRLSDARKSLSTVEDLKAEIVAASESRKELEVKHEAEITNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEVEHRINVEKLKDNLGIHYKQQIDGLQNEMNRKMETMQCETDNLITRQNQLILENSKLRDLQEHLVNSKSEEMNLQINELQKEIEILRREEKEKGSLEQEVQGLQLKTEQLERQLKEKGDDLQEKCAQLDAENSVLKDEKKALEDMLKMYTPLDQEDPSTRKSEDPRWQKEVGMLRKENEDLQQQCLHLSEEIEKQKNTFAFAEKNFEVNYQELQREYTCLLKIRDDLEDTLAKQALQYESKLSALEEELHSQRGSPTTPPKGENSGFAANRTFPLEPLEVGEVVEKDTTELMEKLEVTRREKLELSEKVSGLSEQLKQTHGTIDSLSEEVRALKQEKEQLLLRCGELELLTNANGTENASVCPVQRSPYQAGPVMGTVRDSQGPISKVSEDLAEESKPMTEDKIPFKESGREPLLLPTRTKKPSRVTVEPCESEKLQQELYALKAEQDDLRLQMEAQRLCLFVVYSTHADQVRAYMEKEREEALCSLKDELVSAQQKKIDELHKIHQCQLQHVKVQETGNEPLQVLIERLQKAVSEKCFHISKTLNNVFDECYTPLKCEMNIEEKENSGVYTSQNQSPELREYRYEVQDFQENMQILLGKVTEECSKLLVLQTRLNKINEQQVDGVTFEFAEENVAEVEAGLLSGRSQSGLQGADVSHESKVSEYERQVQELQSLVAAGQLQLKETEANYRAEIQCLQERLQAVSEATVQPSLSMDSVVFKGSGAQKPVYCGSCLREQVDGTAEFSDGFEVRQETNMVKLMEKQYQERLEEEIAKVIVSMSIAFAQQTELSRLSEEKENVIQSEQAHALCSQNEHHLNDITSQCQVGLQTVEATGKNLKEEFKPLSKELGEYRKAVPLSNHDDLDDVLKSEEHGLTISEEIFSKDETFLVRNSSPDEVLVSNMDTSRQLILNEQLEDMRQELVRQYEEHQQATELLRQAHMQQMERQREDQEQLQEEIKRLNQQLTQRSSIDTEHVVSERERVLLEELEALKRLSLAGRKELCCELQHSSTQTQDGNDNQEVEEQTLKDKTLERKPEDIPLDINLSNERYALKKANNRLLKILLDVVKTTSAAEETIGRHVLGILDRSSKSQPATSLLWRSETEASATVCVQEECARAMDESVPSYPGSAIATHDSVWSKVTEEGAELSQRLVRSGFAGPVIDPENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLHCLEELRERLQEESRAREQLAVELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQELLCTNNRLQELESDQRRMEEERELLSRQREAMRADAGPVEQQFLQETEKLMKEKLEVQCQAEKVRGDLQKQVKALEIDVEEQVSRFIELEQEKNAELIDLRQQSQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEHQLKAVPRLLPVSEHQTREVEQLTNHLKEKTDKCSELLLSKEQLQRDVQERNEEIEKLECRVRELEQALLATADPFPKVEEQKRPGAVEVDPELSLEVQLQAERDATDRKQKEITNLEEQLEQFREELENKNEEVQELLMQLEIQKKESTTRLQELQQENRLFKEEIEKLGFTMKESDSLSTQDQPMLFGKFAQLIQEKEIEIDRLNEQFIKLQQQLKLTTDNKVIEEQKDQIRDLETQIECLMSEQELMKKQRAEEAEQLNGVIEKLQQELVSTEQKREGARALPEDEESFKHQLDRVTVEKLGLEKQVETTNQELTDLKNVLKEINFKMDHMTQALCNLNKELPNVPKESVHVTVHELGCDKLQPEGASAQDASQPLESQTSLMCLQESTKASQILEIKSLPLQGSGSTKDFELAQCHKQIDTIQEQDQSEIGMLQKKITNLQKILEKFSAALVSWVQMEAAQDRVQLYQEKQTQTVSSAPERTDTQNVNCLAENNLESHVPTLAVRPAELESRVAEVLSDIMSEKHMETVGKNASETEKEVVALQKLLEEAKKRLKEEREQSPRDRERTAQLTHAGGGSGFSGGLETFEAESATSELASYKERAEKLEEDLLVKESYITSLQKDLGQVKDQLTEAKEKLSHYLEKENGTGEQESRRVPIPESPSVEGGGGSGTMERTGKVSSSNQTPQILVRHAGVQIDLQSERSQEELRDTINQFTEKMERIQELHAAEILDMESRHILETESLKKEHSVAIQLLTKECETLKDMTQYLRCKKGSSISDLADSVAYQSREVYSSDSESDWGQSQGFDTATEGREEGETSDLFPKKIKGLVKAVHSEGMQVLSLSNPLCDDGEDRSVQQLSESWLKERQTYLNTISSLKDLISKMQVQRETEVYDSCQSHDSFSDWRGELLLACQRVFIKERSVLLATFQTELTSLSTRDADGVLNSLEQRIQEQGIEYQTAMDCLQKADRRSLLTEIEDLRAQINGRKMTLEREQEIEKPSQELLDCNLQQKQSHVLEMQLELGSLRDRAAELQEQLSSEKMVVAELKSELAQAKLELGTTLKAQHKRLKELEAFRSEIKEKTDEIHFLSDTLAREQKKSLELQWALEKEKAKSGHHEEWEKEELEDLKFSLEDQKRKNTQLNLLLEQQKQLLNESQQKMESQKMLHDAQLSEEQGRNLGLQALLESEQVRVQEMKSTLDKERELYAQLQSRDDGGQPLPVLPSEDLLKELQKQLEEKHTRIVELLSETEKYKLDSLQTRQQMEKDREVHQKTLQTEQEANTQGQKKMQELQSKVEELQRQLQEKRQQVYKLDLEGKRLQGIMQEFQKQELEPEEKRGSRGLVYQNLNEPASWTFTDDRTRNWVLQQKMGETKDTNFTKLIEINGELDHNHDLEVIRQTLQHVASKLQHVAQKACNRLQFETASDDAFIWIQENIDGIILQLQKLTGQPGDEHSLAPPSSSCGSLTESLMRQNTELTRLINQLTEEKNTLRSIVVKLEELNRCHWHTGAGRDCCSRFSFIDPADIEAIIASEKEVWNREKLSLQKALKRAEAKVYKLKAELRNDALLRSLSPDSEHAALQKIYNKYLRASSFRKALIYQKKYLLLLLGGFQECEDATLGVLARMGGHPALKDPKTITSHPKGFTRFRSAVRVSIAISRMKFLVRRWQQVTSTSSININRDGFGLSPGIEKTDPFYHSSGGLELYGEPRHTTYRSRFDLDYPRSPLPLQNRYPGAPDLNSTSMASSQLHQYNPDKSLTDYVTRLEALKRRLGAIQSGSTTQFHFGMRR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0051018 (protein kinase A binding), GO:0034237 (protein kinase A regulatory subunit binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0065009 (regulation of molecular function), GO:0051602 (response to electrical stimulus), GO:0050790 (regulation of catalytic activity), GO:0044092 (negative regulation of molecular function), GO:0043086 (negative regulation of catalytic activity), GO:0051339 (regulation of lyase activity), GO:0031279 (regulation of cyclase activity), GO:0045761 (regulation of adenylate cyclase activity), GO:0031280 (negative regulation of cyclase activity), GO:0051350 (negative regulation of lyase activity), GO:0007194 (negative regulation of adenylate cyclase activity)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0044297 (cell body), GO:0071944 (cell periphery), GO:0030054 (cell junction), GO:0098794 (postsynapse), GO:0019898 (extrinsic component of membrane), GO:0036477 (somatodendritic compartment), GO:0019897 (extrinsic component of plasma membrane), GO:0120025 (plasma membrane bounded cell projection), GO:0045202 (synapse), GO:0045211 (postsynaptic membrane), GO:0043025 (neuronal cell body), GO:0098590 (plasma membrane region), GO:0097447 (dendritic tree), GO:0005886 (plasma membrane), GO:0099572 (postsynaptic specialization), GO:0097060 (synaptic membrane), GO:0099634 (postsynaptic specialization membrane), GO:0098890 (extrinsic component of postsynaptic membrane), GO:0014069 (postsynaptic density), GO:0030425 (dendrite), GO:0043005 (neuron projection), GO:0098984 (neuron to neuron synapse), GO:0099243 (extrinsic component of synaptic membrane), GO:0032279 (asymmetric synapse), GO:0098839 (postsynaptic density membrane), GO:0098892 (extrinsic component of postsynaptic specialization membrane)