Protein: Pre-B-cell leukemia homeobox 2 isoform X1 (A0A8M6YV86)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
- IPR008422: KN homeodomain (domain) [271-309]
- IPR017970: Homeobox, conserved site (conserved_site) [288-311]
- IPR005542: PBX, PBC domain (domain) [57-251]
- IPR001356: Homeodomain (domain) [250-317]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [252-321]
- IPR050224: Three Amino acid Loop Extension (TALE) homeobox (family) [61-336]
Sequence:
MLQPQQPITGNGPSASRGGGLSVHPGMHPLNSIHPAAQHRPDGADPAGLEGTENGHDNRRDIGDILQQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSMRNVQEEEPPDPQLVRLDNMLLAEGVAGPEKGGGAAAAVSAATSSGGMSPDSSLEHSDYKSKLSQIRNIYHTELEKYEQACSEFTTHVMNLLREQSRTRPVSPREIERMVAIIHRKFSSIQTQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKQCSITVSQVSNWFGNKRIRYKKNIGKYQEEANLYAMKTALGATQSEDSPHTPNSTGSGSFSLSGSADCFLGVPPMNGEQPPYHMGAQDAQSRFSERLYITRESRTNGNWQEQNSPPSAASPGTDHSVDSD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0061061 (muscle structure development), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0009888 (tissue development), GO:0060322 (head development), GO:0030154 (cell differentiation), GO:0048468 (cell development), GO:0060042 (retina morphogenesis in camera-type eye), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009790 (embryo development), GO:0060041 (retina development in camera-type eye), GO:0030901 (midbrain development), GO:0007420 (brain development), GO:0060059 (embryonic retina morphogenesis in camera-type eye), GO:0003007 (heart morphogenesis), GO:0007399 (nervous system development), GO:0042692 (muscle cell differentiation), GO:0048880 (sensory system development), GO:0055001 (muscle cell development), GO:0072359 (circulatory system development), GO:0060537 (muscle tissue development), GO:0007423 (sensory organ development), GO:0090596 (sensory organ morphogenesis), GO:0007417 (central nervous system development), GO:0007517 (muscle organ development), GO:0035051 (cardiocyte differentiation), GO:0007507 (heart development), GO:0007519 (skeletal muscle tissue development), GO:0048592 (eye morphogenesis), GO:0055007 (cardiac muscle cell differentiation), GO:0001654 (eye development), GO:0051146 (striated muscle cell differentiation), GO:0014706 (striated muscle tissue development), GO:0048738 (cardiac muscle tissue development), GO:0060538 (skeletal muscle organ development), GO:0014904 (myotube cell development), GO:0150063 (visual system development), GO:0043010 (camera-type eye development), GO:0048593 (camera-type eye morphogenesis), GO:0014902 (myotube differentiation), GO:0048741 (skeletal muscle fiber development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005667 (transcription regulator complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)