Protein: Cullin 4B (A0A7P0TAQ3)
Organism: Homo sapiens (Human)
InterPro domains:
- IPR001373: Cullin, N-terminal (domain) [308-610]
- IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [776-864]
- IPR019559: Cullin, neddylation domain (domain) [793-858]
- IPR016159: Cullin repeat-like-containing domain superfamily (homologous_superfamily) [191-506]
- IPR016158: Cullin homology domain (domain) [509-737]
- IPR016157: Cullin, conserved site (conserved_site) [837-864]
- IPR045093: Cullin (family) [190-860]
- IPR059120: Cullin-like, alpha+beta domain (domain) [632-765]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [791-864]
- IPR036317: Cullin homology domain superfamily (homologous_superfamily) [505-776]
Sequence:
MFPTGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAKKLVIKNFKDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPGNIELTVNILTMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003684 (damaged DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009628 (response to abiotic stimulus), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0051716 (cellular response to stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0104004 (cellular response to environmental stimulus), GO:0044085 (cellular component biogenesis), GO:1901564 (organonitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0009314 (response to radiation), GO:0046483 (heterocycle metabolic process), GO:0033554 (cellular response to stress), GO:0071214 (cellular response to abiotic stimulus), GO:0019538 (protein metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0071478 (cellular response to radiation), GO:0036211 (protein modification process), GO:0009057 (macromolecule catabolic process), GO:0009416 (response to light stimulus), GO:0043412 (macromolecule modification), GO:1901565 (organonitrogen compound catabolic process), GO:0006508 (proteolysis), GO:0090304 (nucleic acid metabolic process), GO:0006974 (cellular response to DNA damage stimulus), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0030163 (protein catabolic process), GO:0006259 (DNA metabolic process), GO:0042254 (ribosome biogenesis), GO:0009411 (response to UV), GO:0070647 (protein modification by small protein conjugation or removal), GO:0006281 (DNA repair), GO:0010498 (proteasomal protein catabolic process), GO:0051603 (proteolysis involved in protein catabolic process), GO:0016570 (histone modification), GO:0071482 (cellular response to light stimulus), GO:0070914 (UV-damage excision repair), GO:0032446 (protein modification by small protein conjugation), GO:0034644 (cellular response to UV), GO:0016574 (histone ubiquitination), GO:0016567 (protein ubiquitination), GO:0033522 (histone H2A ubiquitination), GO:0010390 (histone monoubiquitination), GO:0035518 (histone H2A monoubiquitination), GO:0006513 (protein monoubiquitination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)