Protein: Insulin-degrading enzyme isoform X2 (A0A8M2BGX2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR011765: Peptidase M16, N-terminal (domain) [54-191]
- IPR050626: Peptidase M16 (family) [25-982]
- IPR032632: Peptidase M16, middle/third domain (domain) [401-681]
- IPR001431: Peptidase M16, zinc-binding site (binding_site) [74-97]
- IPR011249: Metalloenzyme, LuxS/M16 peptidase-like (homologous_superfamily) [32-984]
- IPR054734: Coenzyme PQQ synthesis protein F-like, C-terminal lobe, domain 4 (domain) [789-887]
- IPR007863: Peptidase M16, C-terminal (domain) [217-395]
Sequence:
MILSTVFGRSIRRVSTLSIRMSDPAVKRVVSDIIRSPEDKREYRGLEFTNGLKAILISDPTTDKSSAALDVHMGSLSDPENISGLAHFCEHMLFLGTEKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLQGALDRFAQFFLCPLFDESCKDREVNAVDSEHEKNLMNDAWRLFQLEKATGNPKHPFSKFGTGNKLTLETRPSQQGIDIREELLKFHSTYYSSNLMGLCVLGRETLDELTSMVVKLFGEVENKNVPVPEFPTHPFQEEHLRQFYKVVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIIFHMFQYIQKLRTEGPQEWVFQECKDLNTVAFRFKDKERPRGYTSKVAGLLHYYPLEEILAAEYLLEEFRPDLIEMVLDKLRPENVRVAVVSKSFEGQTDRTEEWYGTQYKQEAITDEAIKKWDNADLNGKFKLPMKNEFIPTNFEIYPLEKDSPSAPTLIKDTAMSKVWFKQDDKFFLPKACLNFEFFSRYLYADPVHCNMTYLFLRLLKDDLREYTYAARLAGLVYGIASGMNAILLSVKGYNDKQHILLKKIIEKMATFEIDEKRFDIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELRDALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQSALEMMQMLEDTLIEHAHTKPLLPSQLIRYREVQVPDGGWYVYQQRNEVHNNCGIEIYYQTDMQNTHENMLLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGVQGLRFIIQSEKAPHYLESRVEAFLKTMEKSVEEMGDEAFQKHIQALAIRRLDKPKKLAAECAKYWGEIISQQYNFDRDNIEVAYLKTLTKEHIMQFYRDLLAIDAPRRHKVSVHVLSREMDSCPLVGEFPAQNDVNLAPAPSLPQPSLVQDMTEFKRSLPLFPLTKPHINFMAAKL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008237 (metallopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0031018 (endocrine pancreas development), GO:0031099 (regeneration), GO:0031100 (animal organ regeneration), GO:0035270 (endocrine system development), GO:0003309 (type B pancreatic cell differentiation), GO:0002064 (epithelial cell development), GO:0060429 (epithelium development), GO:0031016 (pancreas development), GO:0030855 (epithelial cell differentiation), GO:1990798 (pancreas regeneration), GO:0002066 (columnar/cuboidal epithelial cell development), GO:0003323 (type B pancreatic cell development), GO:0002065 (columnar/cuboidal epithelial cell differentiation), GO:0002068 (glandular epithelial cell development), GO:0002067 (glandular epithelial cell differentiation), GO:0035883 (enteroendocrine cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)