Protein: Calcium-transporting ATPase (A0A8M2B4M0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Catalyzes the hydrolysis of ATP coupled with the transport of calcium
Subcellular location: Golgi apparatus, Golgi stack membrane; Multi-pass membrane protein. Membrane; Multi- pass membrane protein
InterPro domains:
- IPR023214: HAD superfamily (homologous_superfamily) [329-671]
- IPR018303: P-type ATPase, phosphorylation site (ptm) [334-340]
- IPR023299: P-type ATPase, cytoplasmic domain N (homologous_superfamily) [342-531]
- IPR006068: Cation-transporting P-type ATPase, C-terminal (domain) [710-882]
- IPR006413: P-type ATPase, subfamily IIA, PMR1-type (family) [7-886]
- IPR044492: P-type ATPase, haloacid dehalogenase domain (domain) [314-677]
- IPR059000: P-type ATPase, A domain (domain) [118-233]
- IPR001757: P-type ATPase (family) [90-715]
- IPR023298: P-type ATPase, transmembrane domain superfamily (homologous_superfamily) [10-887]
- IPR004014: Cation-transporting P-type ATPase, N-terminal (domain) [9-83]
- IPR036412: HAD-like superfamily (homologous_superfamily) [330-729]
- IPR008250: P-type ATPase, A domain superfamily (homologous_superfamily) [120-232]
Sequence:
MVPVLTSKKASELPVNEVACALQADLQFGLNREEVERRRTYHGWNEFDISEDEPLWKKYLSQFKDPLILLLLSSAVISVLMRQFDDAVSITVAIIIVVTVAFVQEYRSEKSLEELGKLVPPECHCIREGHLEHLLARELVPGDTVCLSVGERVPADLRLFESTDLAVDESSLTGETTPCTKTSAPQPAATNGDIASRSNIAFMGTLVRCGKAKGIVIGTGEDSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSLYSLGIIGVIMFVGWLQGKYILDMFTIGVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLSCCNVICSDKTGTLTKNEMTVTHLFTSDGQHAEVTGIGYNNSGEILMDGEVVHGISNTSISKIVEVGCVCNDAMIRHNTLMGRPTEGALIALAMKMGLEGLQHEFVRLEEIPFTSEQKWMAVRVVHRTQRDKPGLFYVKGAYEQVIRFCTSYNSKGVTMPLNNQQRDFYQQQKSYMGSGGLRVLAFASGSEMGSLTFLGLVGIIDPPRAGVKEAVATLISSGVAVKMVTGDSEETAVAIASRLGLYTKGSQCLSGDEVDQMDIQHLSQIVHRVVVFYRASPRHKLKIVKSLQNIGAVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTILSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLLNFPTPLNAMQILWINIIMDGPPAQSLGVEPVDWDVIRKPPRNVRDSIITRSLIVKILVSAFIIVCGTLFVFWRELRDNEITPRDTTMTFTCFVFFDMFNALSSRSQTRMVHEMGLCSNRMFCYAVLGSIMGQLLVIYFPPLQSVFQTESLSILDLLLLFGLTSSVCVVSEIIKKIERLRCGSEKMSDMDSEFHDV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0046873 (metal ion transmembrane transporter activity), GO:0046915 (transition metal ion transmembrane transporter activity), GO:0005384 (manganese ion transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0042592 (homeostatic process), GO:0051234 (establishment of localization), GO:0048878 (chemical homeostasis), GO:0050801 (monoatomic ion homeostasis), GO:0098771 (inorganic ion homeostasis), GO:0006810 (transport), GO:0006811 (monoatomic ion transport), GO:0055071 (manganese ion homeostasis), GO:0055080 (monoatomic cation homeostasis), GO:0006812 (monoatomic cation transport), GO:0030001 (metal ion transport), GO:0000041 (transition metal ion transport), GO:0006828 (manganese ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)