Protein: Growth/differentiation factor 9 (F7F9Q4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted
InterPro domains:
- IPR015617: Growth differentiation factor-9, C-terminal (domain) [335-440]
- IPR029034: Cystine-knot cytokine (homologous_superfamily) [334-440]
- IPR001839: Transforming growth factor-beta, C-terminal (domain) [303-440]
- IPR017948: Transforming growth factor beta, conserved site (conserved_site) [357-372]
- IPR015615: Transforming growth factor-beta-related (family) [13-440]
Sequence:
MAFPSRFLLGVCCFAWLCLLISLSSQASTGESQAGASENLESEADPWSLLLPVDGTDRSGLLPPLFKVLSDRRGETPKLQPDSRALYYMKKLYKTYATKEGVPKPSRSHLYNTVRLFSPCAQQEQAPSNQMTGPLPMVDLLFNLDRVTAMEHLLKSVLLYTLNNSAASSSTVTCVCDLVVKEPMSSSKATPRAPYSFTLRKHRWIEMDVTSLLQPLVASSERSIHLSVNFTCTRDQAPENGTFNMPLSVPPSLILYLNDTSTQAYHSWQSLQSTQRHSQHPGQGSVTTRPVEEEATEVERSPRHRRGQKTLSSETKKPLTASFNLSEYFRQFLFPQNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVRHRYGSPVHTMVQNIIYEKLDPSVPRPSCVPGKYSPLSVLTIEPDGSIAYKEYEDMIATRCTCR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (signaling receptor activator activity), GO:0048018 (receptor ligand activity), GO:0008083 (growth factor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0019953 (sexual reproduction), GO:0050793 (regulation of developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0051240 (positive regulation of multicellular organismal process), GO:0051716 (cellular response to stimulus), GO:0051239 (regulation of multicellular organismal process), GO:0032504 (multicellular organism reproduction), GO:0051094 (positive regulation of developmental process), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0048522 (positive regulation of cellular process), GO:0007276 (gamete generation), GO:0045597 (positive regulation of cell differentiation), GO:2000026 (regulation of multicellular organismal development), GO:0042127 (regulation of cell population proliferation), GO:0060322 (head development), GO:0070887 (cellular response to chemical stimulus), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0070848 (response to growth factor), GO:0071495 (cellular response to endogenous stimulus), GO:0045595 (regulation of cell differentiation), GO:0061036 (positive regulation of cartilage development), GO:0051962 (positive regulation of nervous system development), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0008284 (positive regulation of cell population proliferation), GO:0007420 (brain development), GO:0071559 (response to transforming growth factor beta), GO:0007399 (nervous system development), GO:0061035 (regulation of cartilage development), GO:0032332 (positive regulation of chondrocyte differentiation), GO:0071310 (cellular response to organic substance), GO:0060284 (regulation of cell development), GO:0010720 (positive regulation of cell development), GO:0007417 (central nervous system development), GO:0050769 (positive regulation of neurogenesis), GO:0051960 (regulation of nervous system development), GO:0048232 (male gamete generation), GO:0071363 (cellular response to growth factor stimulus), GO:2000177 (regulation of neural precursor cell proliferation), GO:0071560 (cellular response to transforming growth factor beta stimulus), GO:0050767 (regulation of neurogenesis), GO:0071407 (cellular response to organic cyclic compound)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)