Protein: Caspase 9, isoform CRA_a (A0A9K3Y7W8)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR011029: Death-like domain superfamily (homologous_superfamily) [1-108]
- IPR001309: Peptidase C14, p20 domain (domain) [197-329]
- IPR016129: Peptidase family C14A, His active site (active_site) [262-276]
- IPR002138: Peptidase C14, caspase non-catalytic subunit p10 (domain) [369-453]
- IPR002398: Peptidase C14 family (family) [5-440]
- IPR029030: Caspase-like domain superfamily (homologous_superfamily) [185-452]
- IPR033139: Peptidase family C14A, cysteine active site (active_site) [316-327]
- IPR011600: Peptidase C14, caspase domain (domain) [199-450]
- IPR001315: CARD domain (domain) [1-92]
- IPR015917: Peptidase C14A, caspase catalytic domain (domain) [190-453]
- IPR042147: CASP9, CARD domain (domain) [19-90]
Sequence:
MEEADRQLLRRCRVRLVRELQVAELWDALLSRELFTRDMIEDIQRAGSGSRRDQARQLVIDLETRGRQALPRFISCLEDTGQGSLASFLQSSGQAAKQDPEAVTPLDHLVPVVLGPMGLKSKEQKVVKLDPSQPALGNLTPVVLGPEELWPTRLRPEVLTPETPRPVDIGSGRAHDVCTPGKIERHADMAYTLDSDPCGHCLIINNVNFCPSSGLSTRIGSHVDCEKLQHRFCWLRFMVEVKNDLTAKKMVTALMEMAHRDHRALDCFVVVILSHGCQASHLQFPGAVYGTDGCSVSIERIVNIFNGTGCPSLGGKPKLFFIQACGGEQKDHGFEVAFTSSQDKAFDSDSEPDAVPYQEGPRTLDQLDAVSSLPTPSDILVSYSTFPGFVSWRDKKSGSWYIETLDGVLEQWARSEDLQSLLLRVANAVSEKGVYKQIPGCFNFLRKKLFFKTS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0008233 (peptidase activity), GO:0008234 (cysteine-type peptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0042221 (response to chemical), GO:0048522 (positive regulation of cellular process), GO:0009607 (response to biotic stimulus), GO:0008219 (cell death), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0007568 (aging), GO:0051707 (response to other organism), GO:0044238 (primary metabolic process), GO:0010942 (positive regulation of cell death), GO:0010035 (response to inorganic substance), GO:0012501 (programmed cell death), GO:1901564 (organonitrogen compound metabolic process), GO:0043207 (response to external biotic stimulus), GO:0010941 (regulation of cell death), GO:0070887 (cellular response to chemical stimulus), GO:0048731 (system development), GO:0009617 (response to bacterium), GO:0019538 (protein metabolic process), GO:0046677 (response to antibiotic), GO:0048513 (animal organ development), GO:1901700 (response to oxygen-containing compound), GO:0043170 (macromolecule metabolic process), GO:0002931 (response to ischemia), GO:0010033 (response to organic substance), GO:0072001 (renal system development), GO:0010038 (response to metal ion), GO:0032496 (response to lipopolysaccharide), GO:0006508 (proteolysis), GO:0032355 (response to estradiol), GO:0071310 (cellular response to organic substance), GO:0043067 (regulation of programmed cell death), GO:0033993 (response to lipid), GO:0043068 (positive regulation of programmed cell death), GO:0006915 (apoptotic process), GO:0002237 (response to molecule of bacterial origin), GO:0051604 (protein maturation), GO:0014070 (response to organic cyclic compound), GO:0001822 (kidney development), GO:0010467 (gene expression), GO:0043065 (positive regulation of apoptotic process), GO:0042981 (regulation of apoptotic process), GO:0032025 (response to cobalt ion), GO:0071887 (leukocyte apoptotic process), GO:0071407 (cellular response to organic cyclic compound), GO:0016485 (protein processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)