Protein: Alpha-2u globulin (Q63213)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted
InterPro domains:
- IPR022272: Lipocalin family conserved site (conserved_site) [28-41]
- IPR002971: Major urinary protein (family) [18-177]
- IPR012674: Calycin (homologous_superfamily) [14-179]
- IPR002345: Lipocalin (family) [6-177]
- IPR000566: Lipocalin/cytosolic fatty-acid binding domain (domain) [35-174]
Sequence:
MKLLLLLLCLGLTLVCGHAEEASFERGNLDVDKLNGDWFSIVVASDKREKIEENGSMRVFVQHIDVLENSLGFTFRIKENGVCTEFSLVADKTAKDGEYFVEYDGENTFTILKTDYDNYVMFHLVNVNNGETFQLMELYGRTKDLSSDIKEKFAKLCVAHGITRDNIIDLTKTDRCLQARG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005549 (odorant binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0048511 (rhythmic process), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0008152 (metabolic process), GO:0042592 (homeostatic process), GO:0022414 (reproductive process), GO:0048519 (negative regulation of biological process), GO:0009605 (response to external stimulus), GO:1905953 (negative regulation of lipid localization), GO:0048856 (anatomical structure development), GO:0023057 (negative regulation of signaling), GO:0009653 (anatomical structure morphogenesis), GO:0042221 (response to chemical), GO:0071840 (cellular component organization or biogenesis), GO:0048871 (multicellular organismal-level homeostasis), GO:0051050 (positive regulation of transport), GO:0065008 (regulation of biological quality), GO:0050794 (regulation of cellular process), GO:0044703 (multi-organism reproductive process), GO:0048583 (regulation of response to stimulus), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0048869 (cellular developmental process), GO:0023056 (positive regulation of signaling), GO:0051051 (negative regulation of transport), GO:0048584 (positive regulation of response to stimulus), GO:0019222 (regulation of metabolic process), GO:0032879 (regulation of localization), GO:0007623 (circadian rhythm), GO:0048878 (chemical homeostasis), GO:0044237 (cellular metabolic process), GO:0009893 (positive regulation of metabolic process), GO:0006950 (response to stress), GO:0048585 (negative regulation of response to stimulus), GO:0007610 (behavior), GO:0048522 (positive regulation of cellular process), GO:0032989 (cellular component morphogenesis), GO:1903828 (negative regulation of protein localization), GO:0009966 (regulation of signal transduction), GO:0060255 (regulation of macromolecule metabolic process), GO:0010883 (regulation of lipid storage), GO:0051048 (negative regulation of secretion), GO:0007626 (locomotory behavior), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0001659 (temperature homeostasis), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0062014 (negative regulation of small molecule metabolic process), GO:0016043 (cellular component organization), GO:0031668 (cellular response to extracellular stimulus), GO:0071496 (cellular response to external stimulus), GO:1903531 (negative regulation of secretion by cell), GO:0010888 (negative regulation of lipid storage), GO:0046888 (negative regulation of hormone secretion), GO:0009967 (positive regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:1903530 (regulation of secretion by cell), GO:0051049 (regulation of transport), GO:0045833 (negative regulation of lipid metabolic process), GO:0045913 (positive regulation of carbohydrate metabolic process), GO:0032094 (response to food), GO:0010604 (positive regulation of macromolecule metabolic process), GO:1905952 (regulation of lipid localization), GO:0060341 (regulation of cellular localization), GO:0051224 (negative regulation of protein transport), GO:0033500 (carbohydrate homeostasis), GO:0048512 (circadian behavior), GO:1901700 (response to oxygen-containing compound), GO:0010817 (regulation of hormone levels), GO:0031324 (negative regulation of cellular metabolic process), GO:0010033 (response to organic substance), GO:0009891 (positive regulation of biosynthetic process), GO:0046883 (regulation of hormone secretion), GO:0009991 (response to extracellular stimulus), GO:0062013 (positive regulation of small molecule metabolic process), GO:0042594 (response to starvation), GO:0031325 (positive regulation of cellular metabolic process), GO:0010646 (regulation of cell communication), GO:0070887 (cellular response to chemical stimulus), GO:0009889 (regulation of biosynthetic process), GO:0062012 (regulation of small molecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0010647 (positive regulation of cell communication), GO:0080090 (regulation of primary metabolic process), GO:0045834 (positive regulation of lipid metabolic process), GO:0006091 (generation of precursor metabolites and energy), GO:0007622 (rhythmic behavior), GO:0061179 (negative regulation of insulin secretion involved in cellular response to glucose stimulus), GO:1901654 (response to ketone), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0051055 (negative regulation of lipid biosynthetic process), GO:0045475 (locomotor rhythm), GO:0032990 (cell part morphogenesis), GO:0070201 (regulation of establishment of protein localization), GO:0010675 (regulation of cellular carbohydrate metabolic process), GO:0090278 (negative regulation of peptide hormone secretion), GO:0010468 (regulation of gene expression), GO:0051223 (regulation of protein transport), GO:0090276 (regulation of peptide hormone secretion), GO:0031667 (response to nutrient levels), GO:0010677 (negative regulation of cellular carbohydrate metabolic process), GO:1902533 (positive regulation of intracellular signal transduction), GO:0051252 (regulation of RNA metabolic process), GO:0045721 (negative regulation of gluconeogenesis), GO:0015980 (energy derivation by oxidation of organic compounds), GO:0050708 (regulation of protein secretion), GO:1904950 (negative regulation of establishment of protein localization), GO:1901701 (cellular response to oxygen-containing compound), GO:0009743 (response to carbohydrate), GO:0006753 (nucleoside phosphate metabolic process), GO:0043255 (regulation of carbohydrate biosynthetic process), GO:0071310 (cellular response to organic substance), GO:0009267 (cellular response to starvation), GO:0010906 (regulation of glucose metabolic process), GO:0010676 (positive regulation of cellular carbohydrate metabolic process), GO:0002792 (negative regulation of peptide secretion), GO:0050709 (negative regulation of protein secretion), GO:0010628 (positive regulation of gene expression), GO:0032880 (regulation of protein localization), GO:0006109 (regulation of carbohydrate metabolic process), GO:0046890 (regulation of lipid biosynthetic process), GO:0010907 (positive regulation of glucose metabolic process), GO:0090087 (regulation of peptide transport), GO:0033993 (response to lipid), GO:0042593 (glucose homeostasis), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051046 (regulation of secretion), GO:0014070 (response to organic cyclic compound), GO:0019216 (regulation of lipid metabolic process), GO:0006996 (organelle organization), GO:0001678 (intracellular glucose homeostasis), GO:0031328 (positive regulation of cellular biosynthetic process), GO:1902531 (regulation of intracellular signal transduction), GO:0046676 (negative regulation of insulin secretion), GO:0007005 (mitochondrion organization), GO:0061178 (regulation of insulin secretion involved in cellular response to glucose stimulus), GO:0070584 (mitochondrion morphogenesis), GO:0050796 (regulation of insulin secretion), GO:0071333 (cellular response to glucose stimulus), GO:2001141 (regulation of RNA biosynthetic process), GO:0006111 (regulation of gluconeogenesis), GO:0051897 (positive regulation of protein kinase B signaling), GO:0051896 (regulation of protein kinase B signaling), GO:0007189 (adenylate cyclase-activating G protein-coupled receptor signaling pathway), GO:0043410 (positive regulation of MAPK cascade), GO:0006721 (terpenoid metabolic process), GO:0019217 (regulation of fatty acid metabolic process), GO:1901655 (cellular response to ketone), GO:0006112 (energy reserve metabolic process), GO:0006355 (regulation of DNA-templated transcription), GO:0034284 (response to monosaccharide), GO:0071407 (cellular response to organic cyclic compound), GO:0071396 (cellular response to lipid), GO:0002791 (regulation of peptide secretion), GO:0033574 (response to testosterone), GO:0009060 (aerobic respiration), GO:0071326 (cellular response to monosaccharide stimulus), GO:0009746 (response to hexose), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0009749 (response to glucose), GO:0071331 (cellular response to hexose stimulus), GO:0009749 (response to glucose)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)