Protein: protein-tyrosine-phosphatase (A0A8I6AS38)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR029021: Protein-tyrosine phosphatase-like (homologous_superfamily) [905-1200]
- IPR003961: Fibronectin type III (domain) [329-817]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [430-808]
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [435-812]
- IPR000242: Tyrosine-specific protein phosphatase, PTPase domain (domain) [937-1197]
- IPR000387: Tyrosine-specific protein phosphatases domain (domain) [1112-1186]
- IPR042996: Receptor-type tyrosine-protein phosphatase O (family) [1-1216]
- IPR058859: R-PTP-O-like, Fn3 domain (domain) [342-430]
- IPR016130: Protein-tyrosine phosphatase, active site (active_site) [1134-1144]
- IPR003595: Protein-tyrosine phosphatase, catalytic (domain) [1091-1194]
Sequence:
MGHLPRERRGGRRLLPLLGLFVLLKIVSTFHVTVRDDNNIVVSLEASDVVSPTSVYVVRVAGESKNYFFEFEESNGTLPPPVVFKATYHGLYYIISLVVVSGNVVTKPSRSITVLTKPLPVTSVSIYDYKPSPETGVLFEIHYPEKYNVFSRVNISYWEGKDFRTMLYKDFLKGKTVFNHWLPGICYSNITFQLVSEATFNKSTLVECSGVSHEPKQHRTAPYPPRNISVRFVNLNKNNWEEPSGSFPEDSFIKPQDAIGRDRPFHFPEETPETPASNASSGWPDPNGTEYESTSQPYWWDSASAAPENEEDFVSVLPADYDTEATLGRTEKPTADPFSAFPVQMTLSWLPPKPPTAFDGFNILIEREGNFTDYLTVDEEAHEFVAELKEPGKYRLSVTTFSSSGACETRKSQSAKSLSFYISPTGEWIEELTEKPQHVSVHVLSSTTALLSWTSSQENYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVMYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPTTMTSEWTTYYEIAATVSLTSSVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDATTDLSHSRMLHWMVVAEGRRKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSMLRLVKLEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVLCQKLGSGHDGKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHDSPSVPTFIAVSTMVTEVNPNVVVISVLAILSILLIGLLLVTLVILRKKHLQMARECGAGTFVNFASLEREGKLPYSWRRSVFTFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSRIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMVSEEEQEDWASRHFRINYADEAQDVMHFNYTAWPDHGVPPANAAESILQFVYTVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLKKKQQFCISDVIYENVSKS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0004721 (phosphoprotein phosphatase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0004725 (protein tyrosine phosphatase activity), GO:0016791 (phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0023057 (negative regulation of signaling), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0071704 (organic substance metabolic process), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0044238 (primary metabolic process), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:1901564 (organonitrogen compound metabolic process), GO:0010646 (regulation of cell communication), GO:0048731 (system development), GO:0019538 (protein metabolic process), GO:0009966 (regulation of signal transduction), GO:0043170 (macromolecule metabolic process), GO:0006793 (phosphorus metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0007399 (nervous system development), GO:0006796 (phosphate-containing compound metabolic process), GO:0016311 (dephosphorylation), GO:0006470 (protein dephosphorylation), GO:0035335 (peptidyl-tyrosine dephosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0098794 (postsynapse), GO:0071944 (cell periphery), GO:0045211 (postsynaptic membrane), GO:0098590 (plasma membrane region), GO:0045202 (synapse), GO:0005886 (plasma membrane), GO:0099572 (postsynaptic specialization), GO:0097060 (synaptic membrane), GO:0099634 (postsynaptic specialization membrane), GO:0098984 (neuron to neuron synapse), GO:0014069 (postsynaptic density), GO:0098978 (glutamatergic synapse), GO:0032279 (asymmetric synapse), GO:0098839 (postsynaptic density membrane)