Protein: Uridine 5'-monophosphate synthase (A0A8I6A354)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR004467: Orotate phosphoribosyl transferase domain (domain) [15-178]
- IPR000836: Phosphoribosyltransferase domain (domain) [46-175]
- IPR029057: Phosphoribosyltransferase-like (homologous_superfamily) [7-207]
- IPR023031: Orotate phosphoribosyltransferase (family) [1-231]
- IPR001754: Orotidine 5'-phosphate decarboxylase domain (domain) [252-466]
- IPR018089: Orotidine 5'-phosphate decarboxylase, active site (active_site) [309-322]
- IPR014732: Orotidine 5'-phosphate decarboxylase (family) [254-467]
- IPR011060: Ribulose-phosphate binding barrel (homologous_superfamily) [237-477]
- IPR013785: Aldolase-type TIM barrel (homologous_superfamily) [221-480]
Sequence:
MEVARQALGPLVTELYDVQAFKFGSFVLKSGLSSPVYIDLRGIVSRPRLLSQVADILFQTARNAGISFDSVCGVPYTALPLATVICSANHIPMLIRRKETKDYGTKRLVEGEINPGQTCLVIEDVVTSGASVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAQGIRLHSVCTLSEMLEILEQQKKIDAEMVGRVKRFIQENVFTAANHNGVPPPEKKACKELSFGARAELPGVHPLASKLLTLMQKKETNLCLSADVSEARELLQLADALGPSICMLKTHVDILNDFTLDVMEELTTLAKRHEFLIFEDRKFADIGNTVKKQYESGIFKIASWADVVNAHVVPGSGVVKGLQEVGLPLHRACLLIAEMSSAGSLATGDYTKAAVGMAEEHCEFVIGFISGSRVSMKPEFLHLTPGVQLETGGDHLGQQYNSPQEVVGKRGSDVIIVGRGILAAANRLEAAEMYRKAAWEAYLSRLAVQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016829 (lyase activity), GO:0016830 (carbon-carbon lyase activity), GO:0016757 (glycosyltransferase activity), GO:0016763 (pentosyltransferase activity), GO:0016831 (carboxy-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0051179 (localization), GO:0022414 (reproductive process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048856 (anatomical structure development), GO:0009058 (biosynthetic process), GO:0042221 (response to chemical), GO:0006807 (nitrogen compound metabolic process), GO:0051234 (establishment of localization), GO:0071704 (organic substance metabolic process), GO:0065008 (regulation of biological quality), GO:0044706 (multi-multicellular organism process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0044703 (multi-organism reproductive process), GO:0051716 (cellular response to stimulus), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0009410 (response to xenobiotic stimulus), GO:0046483 (heterocycle metabolic process), GO:0019637 (organophosphate metabolic process), GO:0048513 (animal organ development), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0006793 (phosphorus metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0050878 (regulation of body fluid levels), GO:0007565 (female pregnancy), GO:0006139 (nucleobase-containing compound metabolic process), GO:0070887 (cellular response to chemical stimulus), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0006810 (transport), GO:1901362 (organic cyclic compound biosynthetic process), GO:0006753 (nucleoside phosphate metabolic process), GO:0071466 (cellular response to xenobiotic stimulus), GO:0019438 (aromatic compound biosynthetic process), GO:0048732 (gland development), GO:0046903 (secretion), GO:0006796 (phosphate-containing compound metabolic process), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0007589 (body fluid secretion), GO:0019693 (ribose phosphate metabolic process), GO:0018130 (heterocycle biosynthetic process), GO:0090407 (organophosphate biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0072527 (pyrimidine-containing compound metabolic process), GO:0030879 (mammary gland development), GO:0009117 (nucleotide metabolic process), GO:1901293 (nucleoside phosphate biosynthetic process), GO:0009259 (ribonucleotide metabolic process), GO:0009123 (nucleoside monophosphate metabolic process), GO:0006220 (pyrimidine nucleotide metabolic process), GO:0046390 (ribose phosphate biosynthetic process), GO:0007595 (lactation), GO:0072528 (pyrimidine-containing compound biosynthetic process), GO:0009124 (nucleoside monophosphate biosynthetic process), GO:0009260 (ribonucleotide biosynthetic process), GO:0009218 (pyrimidine ribonucleotide metabolic process), GO:0009129 (pyrimidine nucleoside monophosphate metabolic process), GO:0009165 (nucleotide biosynthetic process), GO:0006221 (pyrimidine nucleotide biosynthetic process), GO:0009161 (ribonucleoside monophosphate metabolic process), GO:0009220 (pyrimidine ribonucleotide biosynthetic process), GO:0009173 (pyrimidine ribonucleoside monophosphate metabolic process), GO:0009156 (ribonucleoside monophosphate biosynthetic process), GO:0009130 (pyrimidine nucleoside monophosphate biosynthetic process), GO:0046049 (UMP metabolic process), GO:0009174 (pyrimidine ribonucleoside monophosphate biosynthetic process), GO:0006222 (UMP biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)