Protein: Caspase 11 (Q91XW7)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR011029: Death-like domain superfamily (homologous_superfamily) [6-84]
- IPR001309: Peptidase C14, p20 domain (domain) [130-258]
- IPR016129: Peptidase family C14A, His active site (active_site) [193-207]
- IPR002138: Peptidase C14, caspase non-catalytic subunit p10 (domain) [286-371]
- IPR002398: Peptidase C14 family (family) [1-373]
- IPR029030: Caspase-like domain superfamily (homologous_superfamily) [110-372]
- IPR033139: Peptidase family C14A, cysteine active site (active_site) [245-256]
- IPR011600: Peptidase C14, caspase domain (domain) [131-368]
- IPR001315: CARD domain (domain) [1-87]
- IPR015917: Peptidase C14A, caspase catalytic domain (domain) [121-371]
Sequence:
MAENNHPDKPLKVLEELGKEFLTEYLEKLVQSNVLKLKEEEKQKFNNAERSDKRWVFVDVLKRKHNQVGKMLLQTFLNVDSGSHHGEANLEMEEPEESVDTLKLCSSEEFTRLCREKKQEIYPIKETNGRTRKALIICNTEFKHLSLRYGANIDISGMKGLLEELGYDVVVKEELTAEGMESEMKDFAALSEHQTSDSTFLVVMSHGTLQGLCGTMHSEATPDVLLYDTIYQIFNNCHCPGLRDKPKVIIVQACRGGNSGEVWIRESSGAHSYRAVDLPRNMEADAVRMSHVEKDFIALYSTTPHHLSYRDKTRGSYFISKLISCFRIHACSCHLFDIFLKVQQSFEKASINSQMPTIDRATLTRYFYLFPGN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0097110 (scaffold protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0019222 (regulation of metabolic process), GO:0008219 (cell death), GO:0009893 (positive regulation of metabolic process), GO:0065009 (regulation of molecular function), GO:0006950 (response to stress), GO:0050790 (regulation of catalytic activity), GO:0044093 (positive regulation of molecular function), GO:0012501 (programmed cell death), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0006952 (defense response), GO:0060255 (regulation of macromolecule metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0006954 (inflammatory response), GO:0051246 (regulation of protein metabolic process), GO:0051336 (regulation of hydrolase activity), GO:0006915 (apoptotic process), GO:0051247 (positive regulation of protein metabolic process), GO:0043085 (positive regulation of catalytic activity), GO:0045862 (positive regulation of proteolysis), GO:0030162 (regulation of proteolysis), GO:0051345 (positive regulation of hydrolase activity), GO:0052547 (regulation of peptidase activity), GO:0010952 (positive regulation of peptidase activity), GO:0052548 (regulation of endopeptidase activity), GO:0010950 (positive regulation of endopeptidase activity), GO:2000116 (regulation of cysteine-type endopeptidase activity), GO:2001056 (positive regulation of cysteine-type endopeptidase activity), GO:0043281 (regulation of cysteine-type endopeptidase activity involved in apoptotic process), GO:0043280 (positive regulation of cysteine-type endopeptidase activity involved in apoptotic process), GO:0006919 (activation of cysteine-type endopeptidase activity involved in apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0036477 (somatodendritic compartment), GO:0042995 (cell projection), GO:0044297 (cell body), GO:0043025 (neuronal cell body), GO:0120025 (plasma membrane bounded cell projection), GO:0043005 (neuron projection)