Protein: phosphatidylinositol-4,5-bisphosphate 3-kinase (A0A8M9Q5U7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR036940: Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily (homologous_superfamily) [894-1094]
- IPR001263: Phosphoinositide 3-kinase, accessory (PIK) domain (domain) [551-744]
- IPR045580: PIK3 catalytic subunit gamma, adaptor-binding domain (domain) [19-208]
- IPR002420: C2 phosphatidylinositol 3-kinase-type domain (domain) [365-536]
- IPR000403: Phosphatidylinositol 3-/4-kinase, catalytic domain (domain) [807-1104]
- IPR018936: Phosphatidylinositol 3-/4-kinase, conserved site (conserved_site) [842-856]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [736-1099]
- IPR029071: Ubiquitin-like domain superfamily (homologous_superfamily) [161-337]
- IPR003113: Phosphatidylinositol 3-kinase, adaptor-binding domain (domain) [50-157]
- IPR016024: Armadillo-type fold (homologous_superfamily) [538-735]
- IPR015433: Phosphatidylinositol 3-/4-kinase (family) [58-1097]
- IPR042236: Phosphoinositide 3-kinase, accessory (PIK) domain superfamily (homologous_superfamily) [536-735]
- IPR000341: Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain (domain) [219-328]
- IPR035892: C2 domain superfamily (homologous_superfamily) [367-534]
Sequence:
MTDKGGATAGFNTLVMEQQASDDEPPVVRREENKRRRRRMKAFTSASAVSMEHIAVEFVLPTTNKNSKTLDTLQLDVTGNWTVEQVKVQLWHRAVTSKLCPEFYQKYSPDYCILLYQKKGNWYEIYDKQQVFQTLDCIRYWKALRKDVGKIHLVVRQQPAEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRKLLTPRKIELSDRDPNLYSMDPWMTTTPMPEYLLSKISNNHILMVIHKETTSQTIKVSIDDTPVQVLQSFFAKITNKRALLGISEDVSESDFVLRVCGREEYLYGNNAIKDFHWIRQCLKNGEEIHLVLEHPPNPEQDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNRKFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTSSKPFTEEVIWNTWLEFNIKIKDLPKGARLSLQVSCGKAQTQTSKETECKNKSRLLYYVNLLLVDHRSLLRQGEFILHMWKMPEKSEDNSSVNADKLTSATNPDKNNSMAVAILLDKYCYPVALPKSKDSPDIEGERGQREMPNHLRKQFEQIIATDPLHPLTSEDKELLWHFRQECMRDPKAYPKFLSSVKWGKQEAVAITHYLLERSTIWDRSVLDVGLVLQLLDCHFSDENVRTIAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCGEEMLQDFRKQVEITEALQKVAREIKQISAEKYDISAQVVFQLRQKLEGLQVLGLPDSFKVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDMLILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKDEILSQWLREKCVNEDKHQQAVDRFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYLMGTTGKKSSPNFLQFQNVCLKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQFNWFLHLVLGIKQGVEKRSA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0016301 (kinase activity), GO:0052742 (phosphatidylinositol kinase activity), GO:0035004 (phosphatidylinositol 3-kinase activity), GO:0016303 (1-phosphatidylinositol-3-kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0048870 (cell motility), GO:0042221 (response to chemical), GO:0050900 (leukocyte migration), GO:0042330 (taxis), GO:0097529 (myeloid leukocyte migration), GO:0006935 (chemotaxis), GO:0030595 (leukocyte chemotaxis), GO:0070887 (cellular response to chemical stimulus), GO:0016477 (cell migration), GO:0071621 (granulocyte chemotaxis), GO:0060326 (cell chemotaxis), GO:0097530 (granulocyte migration), GO:1990266 (neutrophil migration), GO:0030593 (neutrophil chemotaxis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)