Protein: Rho guanine nucleotide exchange factor 28 isoform X2 (A0A8M3ASG5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm
InterPro domains:
- IPR002219: Protein kinase C-like, phorbol ester/diacylglycerol-binding domain (domain) [771-818]
- IPR046349: C1-like domain superfamily (homologous_superfamily) [760-818]
- IPR000219: Dbl homology domain (domain) [965-1162]
- IPR001849: Pleckstrin homology domain (domain) [1203-1307]
- IPR035899: Dbl homology (DH) domain superfamily (homologous_superfamily) [938-1181]
- IPR051632: Rho guanine nucleotide exchange factor (family) [8-1810]
- IPR041020: ARHGEF1-like, PH domain (domain) [1190-1305]
- IPR037819: ARHGEF28, PH domain (domain) [1204-1304]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [1184-1321]
Sequence:
MELSRGEVPLYGQVEVCVKLPLSEFVQEETDYYVLLVGSSLHHVTAAHRTEDHSSIRFTVPGHIVPEKVSVEVYSCTKESKSPISPFCHSEKLSVEYILDEVQEVAEQLMNFETLTSSSHQDILKKLYPKKKVFSEKNHVEQTAQHGTDGVCDPHGGLLQLESLAETEQGFNVCEQGNLSQSEVSGTEEFDPEQHSSVDEKVTQALANLHFLGWDGQAGQENQVLLPRETPLHVAMRLGFPHLSHFLLREFNGQMMVSIANEEGHTPVALAEKHGDPVLITALTHGSALRPVWMCQIWTDCSQQLRICPVTDSISLTVRHQTLINVQNSIQLYREKSKEPDILTRVRHLSELSEGSVHRSDECDADLNNSLKIEDQTLVDSVFEEQLVLCLDEEDEDLSVFNSEKQFSSPGSCTPFHLHSSAAAAVRLTAMLKGSTKDSELNMKYAVPGATEDSSGTDSGMWRMSDTGVSSPGTIDISPAVKDDEGQRGRHPAFRSFSPTSPAGLMLDRFMRATRTTELTYNSSSSPTESCDLSPSLVALEMDSEEDDDDDILMKKPLPQLQPDSKDSTDEQVMSSPAPVLICTRSHSASSACNPAPAKDVEQGVRLRSYSYTSPKISLLPPRFSRDAHPPPADLSQDGVLSSSSGSKSLLHALSLSKSLSLLNPVKHRSSSTSEQPQEKRELRFRRRAQSADDESSAELADSLQHLTLSEFLKEIEEEEWDKYIIPSKTESEKYKVSRTFSFIKSRMYSTRNKNKGKGKEKETKDKQVNGHQFTAGSVLGSTLCEICSKPASGKEVVHCTHCAVSVHKGCKDSSTPCLKKPQDKYSVMTVKSKTASLPQNFIVRESSSSSLQISTSASLPVMTSRDSAPLPCPLSRSVPLTTERFSESPDADSDSPLWRNHIQSEELLQTMESSTSTDSSIIEDSVDSPLQVELLMNAVDLEAESWSLAVEAQFCRMQEKRIIKRQDVIYEFMQTELHHVQTLMVMAEVFRRGMRDEVGLDAETIGRIFPCLDELLQLHRDFLTAMRERRQSCVQNSSSKNFLIHRVGDIFLQQFSQENAEKMKQVYGEFCSHHTEAVSYFKELQQQNKRFQLFIKQQSSNSLVKRREIPECILLVTQRITKYPVLLERILQYTDEGTEEHSDLSRALVLIRELISAVDQYVSQYEQNQKLSEVLGRMENKCSTKLKTGCTFRKQDITSGRNLLHQGPLLWKTATGRLKDVLAFLLSDSLVFLQEKDQKYIFATVDQKPPVISLQKLIVREVANEERGMFLISASSAGPEMYEVHAASKDERNAWMRLIREAVENCPEEEDETTSESEEERRVTEAKVQKIHRLQETLCGHDHLICSNLEEKLHIYAELSVMAGQREAGPEPRLLVRPSTEDVPQAGVLLSAALREAESLRAALSSHCASTPPVPSGPEDLNKPEPCTPPSPPLPPESPLTDPIQSEEEEWRTEESSEAQTFNHNSDSDHNLQLKVSQSVQSLTQLLYSLQAAVTIQDSCYEVQKLLLLLMSSPAPNQQSRPLSITRSGQALHEQERQREAERRREELADVARLRGALVRERQQWERECQARQLQHSELETTLEQRELLCHLEERRLQSERQELQEQLQEYQQSLERLREGQRNVEKEKEKLETQKMLLEGLKHGCQQNLPAMVIPLDGQQTQNHLGIQDEHGSIFVNEAAFISSSVNNRHLHLQHHPQHHHQTVHVHSGSIGYSDSPSAQNSLNSLLARSNHRPSSAGASDHSWTSLRSLTESANNNVGQISHVEESWSAGVTGAGLHQTDVLLVSQPILSMETENRDTDGEETIVYL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0009653 (anatomical structure morphogenesis), GO:0007155 (cell adhesion), GO:0016043 (cellular component organization), GO:0061061 (muscle structure development), GO:0009887 (animal organ morphogenesis), GO:0048729 (tissue morphogenesis), GO:0009888 (tissue development), GO:0031589 (cell-substrate adhesion), GO:0048513 (animal organ development), GO:0007160 (cell-matrix adhesion), GO:0048644 (muscle organ morphogenesis), GO:0007517 (muscle organ development), GO:0060415 (muscle tissue morphogenesis), GO:0006996 (organelle organization), GO:0010256 (endomembrane system organization), GO:0007030 (Golgi organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)