Protein: Cytidine deaminase (A6ITH4)
Organism: Rattus norvegicus (Rat)
Function: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
InterPro domains:
- IPR006262: Cytidine deaminase, homotetrameric (family) [18-142]
- IPR002125: Cytidine and deoxycytidylate deaminase domain (domain) [13-140]
- IPR016193: Cytidine deaminase-like (homologous_superfamily) [14-144]
- IPR016192: APOBEC/CMP deaminase, zinc-binding (binding_site) [65-106]
- IPR050202: Cytidine and Deoxycytidylate Deaminase (family) [13-144]
Sequence:
MAQERPSCAVEPEHVQRLLLSSREAKKSAYCPYSRFPVGAALLTGDGRIFSGCNVENACYPLGVCAERTAIQKAISEGYKDFRAIAIASDLQEEFISPCGACRQVMREFGTNWAVYMTKPDGTFVVRTVQELLPASFGPEDLQKIH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0016814 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines), GO:0019239 (deaminase activity), GO:0004126 (cytidine deaminase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0044281 (small molecule metabolic process), GO:0009607 (response to biotic stimulus), GO:0006807 (nitrogen compound metabolic process), GO:0051716 (cellular response to stimulus), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0043207 (response to external biotic stimulus), GO:0044282 (small molecule catabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:1901698 (response to nitrogen compound), GO:0046483 (heterocycle metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0044248 (cellular catabolic process), GO:1901700 (response to oxygen-containing compound), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901575 (organic substance catabolic process), GO:0071496 (cellular response to external stimulus), GO:0071216 (cellular response to biotic stimulus), GO:0010033 (response to organic substance), GO:1901135 (carbohydrate derivative metabolic process), GO:0034655 (nucleobase-containing compound catabolic process), GO:0097305 (response to alcohol), GO:0044270 (cellular nitrogen compound catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0010243 (response to organonitrogen compound), GO:1901654 (response to ketone), GO:1901136 (carbohydrate derivative catabolic process), GO:0019439 (aromatic compound catabolic process), GO:1901361 (organic cyclic compound catabolic process), GO:0009116 (nucleoside metabolic process), GO:0046700 (heterocycle catabolic process), GO:1901657 (glycosyl compound metabolic process), GO:0014070 (response to organic cyclic compound), GO:0034656 (nucleobase-containing small molecule catabolic process), GO:0072527 (pyrimidine-containing compound metabolic process), GO:0009164 (nucleoside catabolic process), GO:0046898 (response to cycloheximide), GO:1901658 (glycosyl compound catabolic process), GO:0006213 (pyrimidine nucleoside metabolic process), GO:0009119 (ribonucleoside metabolic process), GO:0072529 (pyrimidine-containing compound catabolic process), GO:0046131 (pyrimidine ribonucleoside metabolic process), GO:0042454 (ribonucleoside catabolic process), GO:0046135 (pyrimidine nucleoside catabolic process), GO:0046133 (pyrimidine ribonucleoside catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)