lokahq/bioreason-rl huggingface dataset:
Protein: Interleukin 18 binding protein, isoform CRA_a (A6I6Z8)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [63-172]
- IPR039681: Interleukin-18-binding protein (family) [1-193]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [61-157]
- IPR007110: Immunoglobulin-like domain (domain) [62-147]
- IPR055139: Interleukin-18-binding protein-like domain (domain) [74-165]
Sequence:
MTMRHCGCAADPSPWWVLLLYVHVVILARATSAPLTTATVLTRSSKDPCSSWSPAVPTKQYPTLDVIWPEKEVPLNGTLTLSCTACSRFPNFSILYWLGNGSFIEHLPGRLREGHTSREQRNASTWLHRALVLEELSPSLLSTNFSCLFVDPGQVAQYHVILAQLWDGLKTAPSPSQETLSSHSPGPRSAGPGAP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:0009607 (response to biotic stimulus), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0051707 (response to other organism), GO:0010035 (response to inorganic substance), GO:0043207 (response to external biotic stimulus), GO:0006979 (response to oxidative stress), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0009617 (response to bacterium), GO:1901700 (response to oxygen-containing compound), GO:0010033 (response to organic substance), GO:0034599 (cellular response to oxidative stress), GO:0034097 (response to cytokine), GO:0032496 (response to lipopolysaccharide), GO:0071310 (cellular response to organic substance), GO:0033993 (response to lipid), GO:0062197 (cellular response to chemical stress), GO:0002237 (response to molecule of bacterial origin), GO:0042542 (response to hydrogen peroxide), GO:1901701 (cellular response to oxygen-containing compound), GO:0000302 (response to reactive oxygen species), GO:0034612 (response to tumor necrosis factor), GO:0034614 (cellular response to reactive oxygen species), GO:0070301 (cellular response to hydrogen peroxide), GO:0071345 (cellular response to cytokine stimulus), GO:0071356 (cellular response to tumor necrosis factor)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Polymerase (DNA-directed), delta 4 (F7F6Q0)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR007218: DNA polymerase delta, subunit 4 (family) [1-106]
Sequence:
MGRKRFITDSYPVVKKREGPPGHNKGELAPELGEDTQSLSQEETELELLRQFDLAWQYGPCTGITRLQRWHRAEQMGLKPPVEVYQVLKTHPEDSRFQCSLWHLYPL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016740 (transferase activity), GO:0140097 (catalytic activity, acting on DNA), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0034061 (DNA polymerase activity), GO:0016779 (nucleotidyltransferase activity), GO:0003887 (DNA-directed DNA polymerase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0006259 (DNA metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0006260 (DNA replication), GO:0006261 (DNA-templated DNA replication)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0140535 (intracellular protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0032993 (protein-DNA complex), GO:1902494 (catalytic complex), GO:0140513 (nuclear protein-containing complex), GO:0031974 (membrane-enclosed lumen), GO:0005657 (replication fork), GO:0043625 (delta DNA polymerase complex), GO:0043233 (organelle lumen), GO:1990234 (transferase complex), GO:0043601 (nuclear replisome), GO:0030894 (replisome), GO:0043229 (intracellular organelle), GO:0042575 (DNA polymerase complex), GO:0043227 (membrane-bounded organelle), GO:0043596 (nuclear replication fork), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0061695 (transferase complex, transferring phosphorus-containing groups), GO:0031981 (nuclear lumen), GO:0005694 (chromosome), GO:0005634 (nucleus), GO:0000228 (nuclear chromosome)
Protein: Unc-84 homolog A (C. elegans), isoform CRA_a (A6K1X6)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR040994: SUN coiled coil domain 2 (domain) [678-736]
- IPR045119: SUN domain-containing protein 1-5 (family) [48-913]
- IPR032680: SUN domain-containing protein 1, N-terminal (domain) [66-417]
- IPR012919: SUN domain (domain) [753-914]
Sequence:
MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHRLEPVFDSPRMSRRSLRLITTTAAYSSGDGQTVDTHISTSRATPAKGRETRTVKQRSASKPAFSINHLSGKGLSSSTSHDSSCSLRSATVLRHPVLDESLIREQTKVDHFWGLDDDGDLKGGNKAATQGNGELAAEVASSNGYTCRDCRMLSARTDALTAHSAVHGPTSRVYSRDRTLRPRGASFYLDRTLWLAKYTSSSFASFIVQLFQVVLMKLNFESETYKLKGYESRAYESQSYETKSHESEAHLGHCGRMTAGELSRVDGESLCDDCKGKKHLETHTTTHSQLSQPHRAAGAMGRLCTYTGDLLVRALRRTRAAGWSVAEAMWSVLWLAVTAPGKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGFSLWGQGNFFSLLPMLNWTAMQPAQRVDNPKDMHRPGPLSPSPPLKVDPMASQWPQESDMGQKIASLSAQCHNHDERLAELTVLLQKLQIRVDQVDDGREGLSLWVKDMVGQHLQEIGSIEPPDAKTDFLTLHHDHEVRLSSLEDVLRKLTEKSEAIQKELEETKLRAGSRDEEQPLLDRVQHLELELNLLKSQLSDWQHLRSSCEQADARIQETVQLMFSEDQPGGSLEWLLQKLSSRFVSKDELQVLLHDLELKLLQNITHHITVTGQAPTSEAIVSAMSQAGISGITEAQAHIIVNNALRLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGVPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPRDFAVYGLETEYQEEGQPLGRFTYDQEGDSLQMFHTLERPDQGFQIVELRVLSNWGHPEYTCLYRFRVHGEPIQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005521 (lamin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0001503 (ossification), GO:0009612 (response to mechanical stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: T-cell surface glycoprotein CD3 zeta chain (F7FGL4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein
InterPro domains:
- IPR024128: T-cell surface glycoprotein CD3 zeta subunit (family) [1-164]
- IPR021663: T-cell surface glycoprotein CD3 zeta subunit/High affinity IgE receptor gamma subunit (family) [28-58]
- IPR003110: Phosphorylated immunoreceptor signalling ITAM (repeat) [69-159]
Sequence:
MKWTASVLACILQVQFPGAEAQSFGLLDPKLCYMLDGILFIYGVIVTALYLRAKFSRSADAAAYLQDPNQLYNELNLGRREEYDVLDKKRPRDPEMGGKQQRRRNPQEGVYNALQKDKMAEAYSEIGMKGERRRGKGHDGLYQGLSTATKDTYDALHMQTLPPR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007166 (cell surface receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0043235 (receptor complex), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:0098802 (plasma membrane signaling receptor complex), GO:0098797 (plasma membrane protein complex), GO:0005886 (plasma membrane), GO:0042101 (T cell receptor complex)
Protein: Phosphoglycerate mutase (F7F6N0)
Organism: Rattus norvegicus (Rat)
Function: Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity
InterPro domains:
- IPR013078: Histidine phosphatase superfamily, clade-1 (family) [5-229]
- IPR001345: Phosphoglycerate/bisphosphoglycerate mutase, active site (active_site) [8-17]
- IPR029033: Histidine phosphatase superfamily (homologous_superfamily) [1-258]
- IPR005952: Phosphoglycerate mutase 1 (family) [3-253]
Sequence:
MSKHRLIILRHGEGQWNKENRFCSWVDQKLNSDGLEEARNCGRQLKALNFEFDLVFTSILNRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREKMALNHGEEQVRLWRRSYNVTPPPIEESHPFFHEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWKERISPEILKGKTVLISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAIRPHQFLGNQEAIQAAIKKVDDQGKVRQNK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016853 (isomerase activity), GO:0016866 (intramolecular transferase activity), GO:0016868 (intramolecular transferase activity, phosphotransferases)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0042592 (homeostatic process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0048871 (multicellular organismal-level homeostasis), GO:0002262 (myeloid cell homeostasis), GO:0034101 (erythrocyte homeostasis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048872 (homeostasis of number of cells), GO:0030097 (hemopoiesis), GO:0030218 (erythrocyte differentiation), GO:0030099 (myeloid cell differentiation), GO:0061515 (myeloid cell development), GO:0048821 (erythrocyte development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Interleukin-12 subunit beta (A6HDP1)
Organism: Rattus norvegicus (Rat)
Function: Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis
Subcellular location: Secreted
InterPro domains:
- IPR003961: Fibronectin type III (domain) [233-270]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [23-330]
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [110-329]
- IPR003598: Immunoglobulin subtype 2 (domain) [41-97]
- IPR050676: Interleukin-12 (family) [1-332]
- IPR003530: Long hematopoietin receptor, soluble alpha chain, conserved site (conserved_site) [231-272]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [32-107]
- IPR019482: Interleukin-12 beta, central domain (domain) [123-213]
- IPR007110: Immunoglobulin-like domain (domain) [43-90]
- IPR015528: Interleukin-12 beta (family) [1-332]
Sequence:
MCHQKLTFSWFAMVLLVSPLMAMWELEKDVYVVEVDWRPDAPGETVTLTCDSPEEDDITWTSDQRRGVIGSGKTLTITVREFLDAGQYTCHRGGETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVHRNTDLKFNIKSSSSSPESRAVTCGAASLSAEKVTLNQRDYEKYSVACQEDVTCPTAEETLPIELVVEAQQQNKYENYSTSFFIRDIIKPDPPKNLQVKPLKNSQVEVSWEYPDSWSTPHSYFSLKFFVRIQRKKEKTKETEEECNQKGAFLVEKTSAEVQCKGANICVQAQDRYYNSSCSKWTCVPCRGRS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0019955 (cytokine binding)
Biological Process (BP): GO:0008150 (biological process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0002252 (immune effector process), GO:0001775 (cell activation), GO:0045321 (leukocyte activation), GO:0003008 (system process), GO:0006955 (immune response), GO:0050877 (nervous system process), GO:0002366 (leukocyte activation involved in immune response), GO:0046649 (lymphocyte activation), GO:0002263 (cell activation involved in immune response), GO:0007600 (sensory perception), GO:0002285 (lymphocyte activation involved in immune response), GO:0030101 (natural killer cell activation), GO:0019233 (sensory perception of pain)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005615 (extracellular space), GO:0005576 (extracellular region)
Protein: small monomeric GTPase (F7ERX6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane; Lipid-anchor. Endosome membrane; Lipid-anchor. Melanosome. Membrane; Lipid-anchor
InterPro domains:
- IPR001806: Small GTPase (family) [15-216]
- IPR005225: Small GTP-binding domain (domain) [22-177]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [14-208]
Sequence:
MAGRGGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLPKNEPQNAAGAPGRNRGVDLQESNPASRSQCCSN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0065008 (regulation of biological quality), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0090066 (regulation of anatomical structure size), GO:0035152 (regulation of tube architecture, open tracheal system), GO:0048731 (system development), GO:0006810 (transport), GO:0048513 (animal organ development), GO:0016043 (cellular component organization), GO:0090066 (regulation of anatomical structure size), GO:0032535 (regulation of cellular component size), GO:0030324 (lung development), GO:0030323 (respiratory tube development), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0016192 (vesicle-mediated transport), GO:0006996 (organelle organization), GO:0060541 (respiratory system development), GO:0035150 (regulation of tube size), GO:0001654 (eye development), GO:0007033 (vacuole organization), GO:0016050 (vesicle organization), GO:0150063 (visual system development), GO:0008361 (regulation of cell size), GO:0043010 (camera-type eye development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0098793 (presynapse), GO:0030054 (cell junction), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0008021 (synaptic vesicle), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0030133 (transport vesicle), GO:0043227 (membrane-bounded organelle), GO:0030658 (transport vesicle membrane), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0012506 (vesicle membrane), GO:0070382 (exocytic vesicle), GO:0030672 (synaptic vesicle membrane), GO:0031982 (vesicle), GO:0030659 (cytoplasmic vesicle membrane), GO:0097708 (intracellular vesicle), GO:0099501 (exocytic vesicle membrane)
Protein: X-ray repair complementing defective repair in Chinese hamster cells 4, isoform CRA_a (A0A8I6A2T0)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR053961: XRCC4, N-terminal domain (domain) [17-113]
- IPR038051: XRCC4-like, N-terminal domain superfamily (homologous_superfamily) [1-118]
- IPR053962: XRCC4, coiled-coil domain (domain) [118-194]
- IPR009089: XRCC4, N-terminal domain superfamily (homologous_superfamily) [1-116]
- IPR010585: DNA repair protein XRCC4 (family) [1-323]
- IPR014751: DNA repair protein XRCC4-like, C-terminal (homologous_superfamily) [119-211]
- IPR053963: XRCC4, C-terminal domain (domain) [219-323]
Sequence:
MERKVSRISLASEPNVTYFLQVSWEGTIGSGFVITLTDGHSAWTAKVSESEIAQEADDMAMEQEKYMDELRRALVPESGAAGAYKFIFSKDTQHFSLEKELKDVSFRLGSFNLDKVTNPTEVIRELICYCLDTIAEKQAKNEHLQKENERLLRDWTDVQGRFEKCVSDKEALEADLYQRFILVLNEKKTKIRSLLSEVQQLEKSTKPERETPSSDKIPEEDGLYDGSTDEESGAPVLGADTLDKDDSLFSSPDVTDIAPSRKRRHRMQTNLGTEPKMAPQELPLQEKERLGSSPPQTLKEEGTSAAKMSLETLRNSSPEDLFD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0030332 (cyclin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:1901700 (response to oxygen-containing compound), GO:0010035 (response to inorganic substance), GO:0070887 (cellular response to chemical stimulus), GO:1902074 (response to salt), GO:0010038 (response to metal ion), GO:0010226 (response to lithium ion), GO:0071241 (cellular response to inorganic substance), GO:1901701 (cellular response to oxygen-containing compound), GO:1902075 (cellular response to salt), GO:0071248 (cellular response to metal ion), GO:0071285 (cellular response to lithium ion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0098687 (chromosomal region), GO:1902494 (catalytic complex), GO:0140513 (nuclear protein-containing complex), GO:0140535 (intracellular protein-containing complex), GO:1990391 (DNA repair complex), GO:0000109 (nucleotide-excision repair complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000781 (chromosome, telomeric region), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome), GO:0005634 (nucleus)
Protein: Schlafen 3, isoform CRA_b (A0A0G2K750)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR007421: Schlafen, AlbA_2 domain (domain) [199-303]
- IPR029684: Schlafen family (family) [1-534]
- IPR038461: Schlafen, AlbA_2 domain superfamily (homologous_superfamily) [184-286]
- IPR048729: Schlafen, GTPase-like domain (domain) [379-528]
- IPR031450: Poxin-Schlafen/Schlafen-like, N-terminal domain (domain) [84-192]
Sequence:
MSITVDQDTDYAELVLSIGEITLGEKTRKSMKDSQRRKREAKTFQQAVCTLLNSGGGVAKARIKNQNYDFSRDGVGQDLENFLPHILDFPHEYLDFKQVKDYFLMFVKAWKLKQKGPGITTLKTNLYIRSISSSIELKAVNAVKFLKSRKCSKGRSDSRLSSPGTIVCNEVLNECLNLFNRDCFTCKEKFCFTKATHAEVKLTPKENILEILPQTVSSFANADGGYLFIGLDGKTQEIIGFEAEKSDLVHLESEIEKCIRQLPVTHFCEEREKIKYTCKFMEVHKPGAACSFVCALRVERFCCAVFAAEPESWHVEDSCVKRFTAEDWVKRQMDGPACFSKQDKGPLQSSRLPHSPRSCCPDNPDALQQSAGLPVISGKVISSPEALCGKLFSTQEAHEQLLWAQLDSLPKGTLVVTKRWALDLPLQDKHGVILDTLHIPQDSLLTLHGFVLGGEDLEDDSTLLRELGAELKGYYKQTAVTLKQTLANHGSYTEKIGIAIKITYLGHNKAVSLYDSSSKIHYPTKYYLTTETAKNLEKALAEILGSRESFYSLPRQNCSDHFIFAFFLSFSFLLVFLFWSWGLNPEP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0035295 (tube development), GO:0048286 (lung alveolus development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0030324 (lung development), GO:0030323 (respiratory tube development), GO:0060541 (respiratory system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: RB binding protein 4, chromatin remodeling factor (A6ISI2)
Organism: Rattus norvegicus (Rat)
Subcellular location: Chromosome, telomere. Nucleus
InterPro domains:
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [1-425]
- IPR050459: WD repeat RBAP46/RBAP48/MSI1 (family) [8-413]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [114-409]
- IPR019775: WD40 repeat, conserved site (conserved_site) [193-347]
- IPR022052: Histone-binding protein RBBP4-like, N-terminal (domain) [19-88]
- IPR001680: WD40 repeat (repeat) [112-404]
- IPR020472: PAC1/LIS1-like, WD-40 repeat (repeat) [193-347]
Sequence:
MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDFSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDPEGQGS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009719 (response to endogenous stimulus), GO:0042221 (response to chemical), GO:1901698 (response to nitrogen compound), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:1901700 (response to oxygen-containing compound), GO:0043434 (response to peptide hormone), GO:1901652 (response to peptide), GO:0010243 (response to organonitrogen compound), GO:0060416 (response to growth hormone)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)