Protein: Homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1, isoform CRA_a (Q6P739)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR000626: Ubiquitin-like domain (domain) [10-88]
- IPR029071: Ubiquitin-like domain superfamily (homologous_superfamily) [6-92]
- IPR039751: Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 /2 (family) [3-390]
Sequence:
MEPEPQPEPVTLLVKSPNQRHRDLELSGDRGWSVSRLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLQDLLPKQEKRHVLHLVCNVRSPSKKPEASTKGAESTEQPDNTSQAQYPGDSSSDGLREREVLRNLPPSGWENVSRPEAVQQTFQGLGPGFSGYTTYGWLQLSWFQQIYARQYYMQYLAATAASGAFGPTPSAQEIPVVSTPAPAPIHNQFPAENQPANQNAAAQAVVNPGANQNLRMNAQGGPLVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRQRPVQNFPDDGPPQEAANQDPNNNLQGGLDPEMEDPNRLPVGREVLDPEHTSPSFMSTAWLVFKTFFASLLPEGPPALAN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0044325 (transmembrane transporter binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0042592 (homeostatic process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0048519 (negative regulation of biological process), GO:0048878 (chemical homeostasis), GO:0019725 (cellular homeostasis), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0065009 (regulation of molecular function), GO:0006950 (response to stress), GO:0048523 (negative regulation of cellular process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0009892 (negative regulation of metabolic process), GO:0050801 (monoatomic ion homeostasis), GO:0055082 (intracellular chemical homeostasis), GO:0050790 (regulation of catalytic activity), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0030968 (endoplasmic reticulum unfolded protein response), GO:0060548 (negative regulation of cell death), GO:0010941 (regulation of cell death), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0044092 (negative regulation of molecular function), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0035966 (response to topologically incorrect protein), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0098771 (inorganic ion homeostasis), GO:0080090 (regulation of primary metabolic process), GO:0010033 (response to organic substance), GO:0034976 (response to endoplasmic reticulum stress), GO:0043086 (negative regulation of catalytic activity), GO:0035967 (cellular response to topologically incorrect protein), GO:0055080 (monoatomic cation homeostasis), GO:0043069 (negative regulation of programmed cell death), GO:0051246 (regulation of protein metabolic process), GO:0043067 (regulation of programmed cell death), GO:0071310 (cellular response to organic substance), GO:0051336 (regulation of hydrolase activity), GO:0051248 (negative regulation of protein metabolic process), GO:0006986 (response to unfolded protein), GO:0006873 (intracellular monoatomic ion homeostasis), GO:0055074 (calcium ion homeostasis), GO:0030003 (intracellular monoatomic cation homeostasis), GO:0042981 (regulation of apoptotic process), GO:0051346 (negative regulation of hydrolase activity), GO:0030162 (regulation of proteolysis), GO:0052547 (regulation of peptidase activity), GO:0043066 (negative regulation of apoptotic process), GO:0006874 (intracellular calcium ion homeostasis), GO:0045861 (negative regulation of proteolysis), GO:0034620 (cellular response to unfolded protein), GO:0043154 (negative regulation of cysteine-type endopeptidase activity involved in apoptotic process), GO:0052548 (regulation of endopeptidase activity), GO:0010466 (negative regulation of peptidase activity), GO:0010951 (negative regulation of endopeptidase activity), GO:2000116 (regulation of cysteine-type endopeptidase activity), GO:2000117 (negative regulation of cysteine-type endopeptidase activity), GO:0043281 (regulation of cysteine-type endopeptidase activity involved in apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0031090 (organelle membrane), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098827 (endoplasmic reticulum subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0005789 (endoplasmic reticulum membrane)