lokahq/bioreason-rl huggingface dataset:
Protein: RCG52455 (A6K0R5)
Organism: Rattus norvegicus (Rat)
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis
Subcellular location: Nucleus
InterPro domains:
- IPR017970: Homeobox, conserved site (conserved_site) [274-297]
- IPR021918: Domain of unknown function DUF3528, homeobox protein, eukaryotic (domain) [26-153]
- IPR001356: Homeodomain (domain) [239-303]
- IPR020479: Homeodomain, metazoa (domain) [263-297]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [220-301]
Sequence:
MMDFDERGPCSSNMYLPSCTYYVSGPDFSSLPSFLPQTPSSRPMTYSYSSNLPQVQPVREVTFREYAIEPATKWHPRGNLAHCYSAEELVHRDCLQAPSAAGVPGDVLAKSSANVYHHPTPAVSSNFYSTVGRNGVLPQAFDQFFETAYGTPENLASSDYPGDKNAEKGPPTAAATSAAAVAAAATGAPATSSSDGGGGGGCQEAAAEEKERRRRPESSSSPESSSGHTEDKAGGSGGQRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINRDRLQYYSANPLL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0050896 (response to stimulus), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0042221 (response to chemical), GO:0003006 (developmental process involved in reproduction), GO:0009719 (response to endogenous stimulus), GO:0048608 (reproductive structure development), GO:1901700 (response to oxygen-containing compound), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048732 (gland development), GO:0061458 (reproductive system development), GO:0001655 (urogenital system development), GO:0014070 (response to organic cyclic compound), GO:1901654 (response to ketone), GO:0043627 (response to estrogen), GO:0033993 (response to lipid), GO:0030850 (prostate gland development), GO:0033574 (response to testosterone)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Mas-related G protein-coupled receptor g7 (W8W3G6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
- IPR026234: Mas-related G protein-coupled receptor family (family) [5-289]
- IPR017452: GPCR, rhodopsin-like, 7TM (domain) [25-256]
- IPR000276: G protein-coupled receptor, rhodopsin-like (family) [10-264]
Sequence:
MSSCGIMSCTMIFLSLIIAIVVLVGNAIVIWLLGFQMCRNAFSIYILNLAGADFLFIGFQIGYCFYIIFDIYTIPIKLPLFFIVMLNFAYLCGLSILSAVSIERCLCVMRPFWYRCQLPRHTSAVICTMLWVLSLVLSLSEGKECGFLPGTNISDWCKTIDLIITSWLIVLFVVLLVSSLALVITIFCGLYRIPVTRLYVVIVFTVLFFLLFGLPYGIYLFLLVWAETFYYVFPCGFLPVTIFLSCINSCANPIIYFLVGSVRHHRFQRKSLKLLLQQARQDTPETEEYVEMGSLGRSREVNSLQGTESCFDQA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0004930 (G protein-coupled receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023056 (positive regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0010647 (positive regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0010646 (regulation of cell communication), GO:1902533 (positive regulation of intracellular signal transduction), GO:1902531 (regulation of intracellular signal transduction), GO:0043950 (positive regulation of cAMP-mediated signaling), GO:0043949 (regulation of cAMP-mediated signaling)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009986 (cell surface)
Protein: Neonatal submandibular gland protein C, isoform CRA_b (A6K7R5)
Organism: Rattus norvegicus (Rat)
InterPro domains:
Sequence:
MLRWPINTRARVSTMDLVLRHAVSTLRSQIVTMKLILLYLAVVLCTVCKGSGKGGSSAETGSSRGRGRGSGDSNKVSGPSSSAVVSTDSGDDGNLEDKQVPRFNGDERDGENNSDFFGAGSLDTGNTSDSGSHNLSSGSGSSVRSNVSIGAGPSDQNESADLGGSGRVTCAGKTVSGASSVA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0005975 (carbohydrate metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Carbonic anhydrase (A6J5I5)
Organism: Rattus norvegicus (Rat)
Function: Reversible hydration of carbon dioxide
InterPro domains:
- IPR023561: Carbonic anhydrase, alpha-class (family) [5-181]
- IPR018338: Carbonic anhydrase, alpha-class, conserved site (conserved_site) [29-45]
- IPR036398: Alpha carbonic anhydrase domain superfamily (homologous_superfamily) [1-198]
- IPR001148: Alpha carbonic anhydrase domain (domain) [1-187]
Sequence:
MYIQGLQPHQYRAEQLHLHWGNRNDPHGSEHTVSGKHFAAELHIVHYNSDLYSDFGSASDKSEGLAVLAVLIEIGSVNPSYDKIFSHLQHVKYKGQQVLIPGFNIEELLPESPGEYYRYEGSLTTPPCYPTVLWTVFRNPVQISQEQLLALETALYFTHMDDPSPREMVNNFRQVQKFDERLVYISFRQGIILSVALAGVLGISIVLAVSVWLFKRKKSKKGDNKGVIYKPAIKKEAEVHA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016835 (carbon-oxygen lyase activity), GO:0016836 (hydro-lyase activity), GO:0004089 (carbonate dehydratase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0048511 (rhythmic process), GO:0022414 (reproductive process), GO:0032504 (multicellular organism reproduction), GO:0042698 (ovulation cycle), GO:0048609 (multicellular organismal reproductive process), GO:0044849 (estrous cycle)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0045178 (basal part of cell), GO:0045177 (apical part of cell), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0009925 (basal plasma membrane), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0016324 (apical plasma membrane), GO:0016323 (basolateral plasma membrane)
Protein: Hairy/enhancer-of-split related with YRPW motif protein 1 (A6IH72)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR003650: Orange domain (domain) [120-167]
- IPR011598: Myc-type, basic helix-loop-helix (bHLH) domain (domain) [49-110]
- IPR050370: Hairy and Enhancer of Split/HEY-related (family) [46-210]
- IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [43-107]
Sequence:
MKRAHPDYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQVLARKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHGGLGHIPWGSAFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0042802 (identical protein binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0071495 (cellular response to endogenous stimulus), GO:0007166 (cell surface receptor signaling pathway), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0009725 (response to hormone), GO:0048545 (response to steroid hormone), GO:0032870 (cellular response to hormone stimulus), GO:0014070 (response to organic cyclic compound), GO:0071310 (cellular response to organic substance), GO:0033993 (response to lipid), GO:0007219 (Notch signaling pathway), GO:0031960 (response to corticosteroid), GO:0071383 (cellular response to steroid hormone stimulus), GO:0071407 (cellular response to organic cyclic compound), GO:0071396 (cellular response to lipid), GO:0051384 (response to glucocorticoid), GO:0071384 (cellular response to corticosteroid stimulus), GO:0071385 (cellular response to glucocorticoid stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: RCG45587 (A6JU26)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR036612: K Homology domain, type 1 superfamily (homologous_superfamily) [67-428]
- IPR004088: K Homology domain, type 1 (domain) [79-422]
- IPR004087: K Homology domain (domain) [76-426]
- IPR015096: Far upstream element-binding protein, C-terminal (domain) [505-531]
Sequence:
MAELVQGQSAPVGLKAEDFVDALHRVRQIAAKIDSIPHLNNSTPLVDPSVYGYGVQKRPLDDGVGNQLGALVHQRAVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDIDGNSTIQELLIPASKVGLVIGKGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDPFKVQQAREMVLEIIREKDQADFRGVRSDFTSRAGGGSIEVSVPRFVVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAARIINELILTAQEREILGGLTGTRGRGRGRGDWSVGTPGGIQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNTDPNLRIFTIRGAPQQIEVARHLIDEKVGGASLGAPTAFGQSPFSQPPAAPHQNTFPPRAFPNIAAKVNGNPHSTPVSGPPAFLTQGWGSTYQAWQQPTQQVPSQQSQPQNSQPDYSKAWEDYYKKQGHTTSAAPQASSPPDYTMAWAEYYRQQAAFYGQTLGQAQAHSQEQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003697 (single-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051641 (cellular localization), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0006403 (RNA localization), GO:0008298 (intracellular mRNA localization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043198 (dendritic shaft), GO:0042995 (cell projection), GO:0044297 (cell body), GO:0036477 (somatodendritic compartment), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043025 (neuronal cell body), GO:0043233 (organelle lumen), GO:0120025 (plasma membrane bounded cell projection), GO:0097447 (dendritic tree), GO:0005844 (polysome), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043005 (neuron projection), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0030425 (dendrite), GO:0031981 (nuclear lumen), GO:0005840 (ribosome), GO:0005634 (nucleus)
Protein: Scinderin (A6HBD0)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell projection, podosome. Cytoplasm, cytoskeleton
InterPro domains:
- IPR007122: Villin/Gelsolin (family) [17-560]
- IPR036180: Gelsolin-like domain superfamily (homologous_superfamily) [195-382]
- IPR007123: Gelsolin-like domain (domain) [28-553]
- IPR029006: ADF-H/Gelsolin-like domain superfamily (homologous_superfamily) [4-565]
Sequence:
MAQELQHPEFARAGKQAGLQVWRVEKLELVPVPQGAYGDFYVGDAYLVLHTTKSSRGFSYRLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQSRELQGYESTDFVGYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWQSFNKGDCFIIDLGTVLGRKPELPDGDNDDDVIADISNRKMAKLYMVSDASGSMKVTLVAEENPFSMGMLLPEECFILDHGAAKQIFVWKGKNANPQERKTAMKTAEEFLHKMNYSANTQIQVLPEGGETPIFKQFFKDWKDKDQSDGFGKVYITEKVAQIKQIPFDASKLHSSPQMAAQHNMVDDGSGGVEIWRVENSGRVQIDPSSYGEFYGGDCYIILYTYPRGQIIYTWQGADATRDELTMSAFLTVQLDRSLGGQAVQVRVSQGKEPAHLLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEIEEVPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESVKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0003779 (actin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050793 (regulation of developmental process), GO:0050794 (regulation of cellular process), GO:0045595 (regulation of cell differentiation), GO:0045664 (regulation of neuron differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex)
Protein: Complement component 8, alpha polypeptide (Predicted) (A6JRT8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted
InterPro domains:
- IPR048831: Complement components C8A/B/C6, EGF-like domain (domain) [502-529]
- IPR001862: Membrane attack complex component/perforin/complement C9 (family) [58-519]
- IPR002172: Low-density lipoprotein (LDL) receptor class A repeat (repeat) [95-132]
- IPR036055: LDL receptor-like superfamily (homologous_superfamily) [98-135]
- IPR023415: Low-density lipoprotein (LDL) receptor class A, conserved site (conserved_site) [108-130]
- IPR020864: Membrane attack complex component/perforin (MACPF) domain (domain) [136-498]
- IPR036383: Thrombospondin type-1 repeat superfamily (homologous_superfamily) [37-587]
- IPR020863: Membrane attack complex component/perforin domain, conserved site (conserved_site) [330-341]
- IPR000884: Thrombospondin type-1 (TSP1) repeat (repeat) [38-587]
Sequence:
MFTVAFFGLSLMAWHSGVTAQEKVNQRVTRAVTPGAVACQLSDWSEWTDCFPCQNEKYRYRSLLQPSKFGGTICSGDIWDKANCDSPTPCLRQAQCGQDFQCRETGRCLKRHLVCNGDQDCLDGSDEDNCDDARVIEDDCRQYEPIPGSERAALGYNILTQEEGQSVYDAKYYGGQCETVYNGDWRRLQYDPTCERLYYGEDEKYFRKPYNFLKYHFEALADTLISSEFYDDANDLFSKIQRDKSQSNSVTFGISPAKSPITLDASVSWSDESSFMKELSKYNEKKYSFMRVSTKVQTAHFKMRRHNIVLDEGMMESLMELPEQFNYGMYSKFINDYGTHYITSGTMGGIYEYVLVLDKEKMRIHGITVEDVKKCIGGGVGLQFGEKIIGEGDLSGESCVMTGDGNQDKRKKDLAVEDIISRVQGGSSRWSTGLAHNSSAITYRSWGRSLKYNPVVIDFEMQPIYQLLQHTNLGPLETKRRNLRRALDQYLMEFNACRCGPCFNNGVPILEGTSCSCQCSMGRQGPACESMVLEAMEGAKADGRWSCWSSWSECRGGSRERRRQCNNPAPQNGGAPCLGKSLQTQAC
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0001848 (complement binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0001775 (cell activation), GO:0045321 (leukocyte activation), GO:0048584 (positive regulation of response to stimulus), GO:0006955 (immune response), GO:0002684 (positive regulation of immune system process), GO:0048583 (regulation of response to stimulus), GO:0002682 (regulation of immune system process), GO:0002252 (immune effector process), GO:0002253 (activation of immune response), GO:0048522 (positive regulation of cellular process), GO:0050776 (regulation of immune response), GO:0006956 (complement activation), GO:0002697 (regulation of immune effector process), GO:0006959 (humoral immune response), GO:0050778 (positive regulation of immune response), GO:0002699 (positive regulation of immune effector process), GO:0006956 (complement activation), GO:0046649 (lymphocyte activation), GO:0002263 (cell activation involved in immune response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Similar to Ofd1 protein (Predicted) (A6K2I3)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR006594: LIS1 homology motif (conserved_site) [70-102]
- IPR055289: Centriole and centriolar satellite OFD1 (family) [11-1025]
Sequence:
MAQSTMPHKCDDVLSQDELRKKLYQTFKDRGILDTLKTQLRNQLVHELMHPVLSGEVKPPSISVEGSSLLIGASNSLVADHLQRCGYEYSLSVFFPESGLAKEKIFTMQDLLQLIRINPSSSLYKSLISGFDKDNQKGFLMSFLKELAEYHQTKESCDVETQTSTTFPSQVSLAEKFQLIDDQFAEAFPHRPKLESLETKLNEYKKEIQQQLQVEMCQKLKYFREAEITKVRMEEKRKYEKELAEFRNEFERTCQAKNEALISQEKNTLERIKKHQEMETKEIYAQRQLLLNDIDLLRGREAELKERIEAFELTQKLQEEKNKNEAEALRRREQNLKNIEEAYEQKLKTELLKYQLELKDDYITRTNKLLEEERKNKEKTFHLQEELTVINSKKEELSKSVQRMKEVELELESVKAQFFAMSKQNHSLNEKLKEMSDYSQLKEEKVELQAQNKLLKQQLEENRNENLRLLDRITQPPPELLVFQKELQKTEKAMALEHKGFETHRQALQKQLQSEIENSTQLRTQISEYDASVKRLTVQVADLKSQLKQTQTALENEVFRNPKRSLTLHSLTGLLSGKMAPHNEDTSGDFLNVPLEQNKVMAGAVVSRVTPYVNTATEASSPDSDLEFVASSTKAKVKELEQEAERLEKAFRTYYQRVTQNPSMSPQPAKSPSSVYSVGALRSIASSSRDRHVPAEDRVVSEQPLADILKEEKSDVSKAFVGSMVSRPRRTSSSTRLSSTPHPKSRRSLDNEMYLEGLRRLHITSSSPCLDRPSESPAASPTPCPERTPQPSSVPSRHSFSGPSFSSPPEQNASLYQRQTEMQDKSEFSNVDKQSLKDKEKFEPSFRWNKPEQFEAEGLHPAGDMPGIDVAAATLSSRPISYNHPSGAVQSQTGEQKEQQIWELHMKERRQREEQRQNERQEALERERRELEKLEQERRMIEESLKSEIEEELEKSVQEQKDKSAHGENPLEKYMKIIQQRQEQSSADKSSKKSGKECSLVDMMIPSDKDDSSPGFSHEEPDDIW
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0015631 (tubulin binding), GO:0043015 (gamma-tubulin binding), GO:0043014 (alpha-tubulin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0006996 (organelle organization), GO:0030030 (cell projection organization), GO:0022607 (cellular component assembly), GO:0044782 (cilium organization), GO:0070925 (organelle assembly), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0060271 (cilium assembly), GO:0120031 (plasma membrane bounded cell projection assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0034451 (centriolar satellite), GO:0036064 (ciliary basal body), GO:0005814 (centriole), GO:0120025 (plasma membrane bounded cell projection), GO:0005813 (centrosome), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0005929 (cilium), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015630 (microtubule cytoskeleton)
Protein: RCG55152, isoform CRA_a (A6IIW6)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR009991: Dynactin subunit 3 (family) [1-184]
Sequence:
MAALTDVQRLQSRVEELERWVYGPGGTRGSRKVADGLVKVQVALGNIASKRERVKILYKKIEDLIKYLDPEYIDRIAIPEASKLQFILAEEQFILSQVALLEQVNTLVPMLDSASIKAVPEHAARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELLCQLEAAKQVKPAAE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007017 (microtubule-based process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005875 (microtubule associated complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0005869 (dynactin complex), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0099513 (polymeric cytoskeletal fiber), GO:0005874 (microtubule), GO:0015629 (actin cytoskeleton), GO:0015630 (microtubule cytoskeleton)
Protein: Eukaryotic translation initiation factor 2A (A6JVI7)
Organism: Rattus norvegicus (Rat)
Function: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner
InterPro domains:
- IPR011387: Translation initiation factor 2A (family) [8-578]
- IPR013979: Translation initiation factor, beta propellor-like domain (domain) [216-411]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [35-377]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [14-425]
Sequence:
MAPSTPLLTVRGSEGLYMVNGPPHFTESTVLPREPGKNCKVYTFSKDGTLFAWSNGEKVNIINVANKGLLHSFDLPKAVCLEFSPNNTVLATWQPYTTSKDGTAGTPNLQLYDVKTGTCLKSFIQKKMQNWCPSWSDDEIICARNVNNEVHFFENNNFNTIANKLHLQKVNDFNLSPGTQPFKVAVYVPGSKGAPSFVRLYQYPNFAGPQAALANKSFFKADKVTMLWNKKATAVLVIASTDVDKTGASYYGEQTLHYIATNGESAVVQLPKNGPIYDVAWNPSSTEFCAVYGFMPAKATVFNLKCDPVFDFGTGPRNAAFYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDSTYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSLLYKYDVPSNGELWQVSWQPFLDGIFPAKTITYQAVPSEVPSEEPKVATAYRPPALRNKPVTSSKLHEEEPPQNMKPHPSSDKPLSKTALKNQRKHEAKKAAKQEARNDLAPTPVPQSAPRSTVTQSASGDPEVDKKIKNLKKKLKAIEQLKEQAAAGKQLEKNQLEKIQKETALLQELEDLELGV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0000049 (tRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0006950 (response to stress), GO:0042594 (response to starvation), GO:0009991 (response to extracellular stimulus), GO:0031667 (response to nutrient levels), GO:1990928 (response to amino acid starvation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)