lokahq/bioreason-rl huggingface dataset:
Protein: Decay accelarating factor 1 (A9CMA5)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR000436: Sushi/SCR/CCP domain (domain) [34-285]
- IPR050350: Complement & Cell Adhesion Regulators (family) [29-314]
- IPR035976: Sushi/SCR/CCP superfamily (homologous_superfamily) [36-284]
Sequence:
MIRTRAPGTRAPPPPPLLLSLSLLLLLLSPTVSGDCGPPPDIPNATPNSGKHTKFAHQSQVTYSCNKGFKQIPDKPNTVVCLENDQWSNYETFCNKTCSAPLRLNYASLKKEYRNMNFFPIGTTVEFECRPGFQKVTSRTGKSTCLEELVWSPVVEFCKKRACPNPRELKNGHINIPTDILFGSEIIFSCDKGYKLVGVTSTFCSITGNAVDWDDVFPVCTTIFCPDPPKINNGRIREESDSYAYRQSVTYSCDQGFILVGNSSVHCTLNGEVGEWSSAPPKCIERHKVPTKTPPEVDIPSTMPHESTLINFPSTRAPLSHKPTTVKVPATQHVPVSKTTVRHPTRTSKDRGESNSGGDHFIY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140678 (molecular function inhibitor activity), GO:0004857 (enzyme inhibitor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0048519 (negative regulation of biological process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0019953 (sexual reproduction), GO:0044706 (multi-multicellular organism process), GO:0042221 (response to chemical), GO:0002683 (negative regulation of immune system process), GO:0009719 (response to endogenous stimulus), GO:0044703 (multi-organism reproductive process), GO:0048583 (regulation of response to stimulus), GO:0002682 (regulation of immune system process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0048585 (negative regulation of response to stimulus), GO:0007276 (gamete generation), GO:0050777 (negative regulation of immune response), GO:0007567 (parturition), GO:0050776 (regulation of immune response), GO:1901698 (response to nitrogen compound), GO:0002697 (regulation of immune effector process), GO:0002698 (negative regulation of immune effector process), GO:1901700 (response to oxygen-containing compound), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0007283 (spermatogenesis), GO:0043434 (response to peptide hormone), GO:1901652 (response to peptide), GO:0030449 (regulation of complement activation), GO:0010243 (response to organonitrogen compound), GO:0002921 (negative regulation of humoral immune response), GO:0045916 (negative regulation of complement activation), GO:0002920 (regulation of humoral immune response), GO:0048232 (male gamete generation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0045177 (apical part of cell), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0016324 (apical plasma membrane)
Protein: U1 small nuclear ribonucleoprotein 70 kDa (F7FIU1)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR034143: snRNP70, RNA recognition motif (domain) [102-187]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [90-215]
- IPR022023: U1 small nuclear ribonucleoprotein of 70kDa N-terminal (domain) [3-94]
- IPR000504: RNA recognition motif domain (domain) [103-181]
- IPR035979: RNA-binding domain superfamily (homologous_superfamily) [88-204]
- IPR051183: U1 snRNP 70 kDa and U11/U12 snRNP 35 kDa (family) [29-280]
Sequence:
MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKDERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGGGGGGGGGGGGGGGGDMAEPSEAGDGAPDDGPPGELGPEGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDREHKRGERGSERGRDEARGGGGSGQDNGLEGLGSDGRDMYMEAEGGDGYMAPENGYLMEAAPE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0043021 (ribonucleoprotein complex binding), GO:0070990 (snRNP binding), GO:1990446 (U1 snRNP binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0071495 (cellular response to endogenous stimulus), GO:1901700 (response to oxygen-containing compound), GO:0070848 (response to growth factor), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0071559 (response to transforming growth factor beta), GO:0034097 (response to cytokine), GO:1901701 (cellular response to oxygen-containing compound), GO:0071310 (cellular response to organic substance), GO:0033993 (response to lipid), GO:0071363 (cellular response to growth factor stimulus), GO:0032526 (response to retinoic acid), GO:0071560 (cellular response to transforming growth factor beta stimulus), GO:0071345 (cellular response to cytokine stimulus), GO:0034612 (response to tumor necrosis factor), GO:0071300 (cellular response to retinoic acid), GO:0071396 (cellular response to lipid), GO:0071356 (cellular response to tumor necrosis factor)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0140513 (nuclear protein-containing complex), GO:0005737 (cytoplasm), GO:0120114 (Sm-like protein family complex), GO:0030532 (small nuclear ribonucleoprotein complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0097525 (spliceosomal snRNP complex), GO:0043231 (intracellular membrane-bounded organelle), GO:0005685 (U1 snRNP), GO:0005634 (nucleus)
Protein: MinK-related peptide 3 (A0A8I5ZKN5)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR000369: Potassium channel, voltage-dependent, beta subunit, KCNE (family) [2-159]
Sequence:
MLRMEPLNSTHPSAAASSSPLESHVSSNSGGNGNEYFYILVVMSFYGIFLIGIMLGYMKSKRREKKSSLLLLYKDEERLWGEAMKPLPMMSGLRSGQVPMMLNMLQESVAPALSCTLCSMEGDSVSSESSSPDVHLTIQEEGADEELEETSETPLNESSEGSTENIHQNS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0044325 (transmembrane transporter binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0065008 (regulation of biological quality), GO:0051641 (cellular localization), GO:0031503 (protein-containing complex localization), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0051234 (establishment of localization), GO:0051050 (positive regulation of transport), GO:0033036 (macromolecule localization), GO:0048522 (positive regulation of cellular process), GO:1903829 (positive regulation of protein localization), GO:0051049 (regulation of transport), GO:0046907 (intracellular transport), GO:0032388 (positive regulation of intracellular transport), GO:0060341 (regulation of cellular localization), GO:0006810 (transport), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0051222 (positive regulation of protein transport), GO:0031647 (regulation of protein stability), GO:0045184 (establishment of protein localization), GO:0006886 (intracellular protein transport), GO:0090316 (positive regulation of intracellular protein transport), GO:0051223 (regulation of protein transport), GO:0071705 (nitrogen compound transport), GO:0032386 (regulation of intracellular transport), GO:1904951 (positive regulation of establishment of protein localization), GO:0015031 (protein transport), GO:0070201 (regulation of establishment of protein localization), GO:0071702 (organic substance transport), GO:0050821 (protein stabilization), GO:0032880 (regulation of protein localization), GO:0008104 (protein localization), GO:0032386 (regulation of intracellular transport), GO:1903955 (positive regulation of protein targeting to mitochondrion), GO:1903747 (regulation of establishment of protein localization to mitochondrion), GO:0033157 (regulation of intracellular protein transport), GO:1903749 (positive regulation of establishment of protein localization to mitochondrion), GO:1903533 (regulation of protein targeting), GO:1903214 (regulation of protein targeting to mitochondrion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0045177 (apical part of cell), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0016324 (apical plasma membrane)
Protein: Tissue factor pathway inhibitor 2, isoform CRA_b (A6K2A9)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR008296: Tissue factor pathway inhibitor-like (family) [2-179]
- IPR036880: Pancreatic trypsin inhibitor Kunitz domain superfamily (homologous_superfamily) [1-172]
- IPR050098: Tissue factor pathway inhibitor/Kunitz-type serine protease inhibitor-like (family) [55-175]
- IPR020901: Proteinase inhibitor I2, Kunitz, conserved site (conserved_site) [23-161]
- IPR002223: Pancreatic trypsin inhibitor Kunitz domain (domain) [1-166]
Sequence:
MGPCKALIPKFYYDRDQKKCRRFKYGGCLGNANNFHSRKLCEHTCGNKEKVPWVCRSAVRTYPCDKPNTEFFFNLKTMTCEPLRPGLCSRTTNVFPEEAMCKSLCEPRKSIPSFCSSPKDEGLCSANVTRYYFNSRNKACETFTYTGCGGNENNFYYLDACNRACVKALKKPKRRKIGDFLPRFWKLRS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0005201 (extracellular matrix structural constituent)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0034405 (response to fluid shear stress), GO:0033554 (cellular response to stress), GO:0071498 (cellular response to fluid shear stress)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Postmeiotic segregation increased 2 (S. cerevisiae) (Predicted), isoform CRA_a (A6K1J3)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR037198: MutL, C-terminal domain superfamily (homologous_superfamily) [356-534]
- IPR020568: Ribosomal protein uS5 domain 2-type superfamily (homologous_superfamily) [2-53]
- IPR042120: MutL, C-terminal domain, dimerisation subdomain (homologous_superfamily) [361-534]
- IPR014790: MutL, C-terminal, dimerisation (domain) [358-502]
- IPR038973: DNA mismatch repair protein MutL/Mlh/Pms-like (family) [3-537]
- IPR042121: MutL, C-terminal domain, regulatory subdomain (homologous_superfamily) [398-497]
- IPR013507: DNA mismatch repair protein, S5 domain 2-like (domain) [3-48]
- IPR014721: Small ribosomal subunit protein uS5 domain 2-type fold, subgroup (homologous_superfamily) [1-53]
Sequence:
MYNRHQYPFVVLNVSVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLMGMFDSDANKLSVNQQPLLNVEGNLVKLHTAEVGEQENSPSLRITAEEKRVASVSRLREAYSLHRTTETKSWGPETPELKQSFPSQKRGVSSSCPSDIISYRGLCGSQDKLVSPTDSPGDCMDREKGEKDSGLSSTSAGSEEGFSTPEVASSFSSDCNVSSPEDRPSQENTNCGEQFLEVDDHLSGTGHHLKPEDNGYKCRASLPPTRLSPSNAKRFRTEDRPSNVGVPQNTSAAEVDVAVKINKKIVLLDFSLSSLAKQMKQLQHLKQQSKSEHNYRKFRAKICPGENQAAEDELRREIRKSMFAEMEILGQFNLGFIVTKLKEDLFLVDQHAADEKYNFEMLQQHTVLQAQRLITPQTLNLTAVNEAVLIENLEIFRKNGFDFIIDEDAPVTERAKLISLPTSKNWTFGPQDIDELIFMLSDSPGVMCRPSRVRQMFASRACRKSVMIGTALSASEMKKLISHMGEMDHPWNCPHGRPTMRHIANLDVISQN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0009410 (response to xenobiotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0099086 (synaptonemal structure), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0000795 (synaptonemal complex), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0005634 (nucleus), GO:0031981 (nuclear lumen), GO:0005694 (chromosome), GO:0000228 (nuclear chromosome), GO:0000793 (condensed chromosome), GO:0000794 (condensed nuclear chromosome)
Protein: Hdac11 protein (F7EU26)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR023696: Ureohydrolase domain superfamily (homologous_superfamily) [13-319]
- IPR000286: Histone deacetylase HDAC (family) [139-261]
- IPR023801: Histone deacetylase domain (domain) [35-316]
- IPR037138: Histone deacetylase domain superfamily (homologous_superfamily) [14-331]
- IPR044150: Histone deacetylase 11 (domain) [35-319]
Sequence:
MPHATQLYQHVPEKRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDGMLVEAREASEEDLLVVHTRRYLNELKWSFVVATITEIPPVIFLPNFLVQRKVLRPLRTQTGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMGDKRVYIMDVYNRHIYPGDRFAKEAIRRKVELEWGTEDEEYLEKVERNVRRSLQEHLPDVVVYNAGTDVLEGDRLGGLSISPAGIVKRDEVVFRVVRAHDIPILMVTSGGYQKRTARIIADSILNLHDLGLIGPEFPYVPARNSSIPLLSRAVP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0003682 (chromatin binding), GO:0016787 (hydrolase activity), GO:0019213 (deacetylase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0021782 (glial cell development), GO:0022008 (neurogenesis), GO:0010001 (glial cell differentiation), GO:0007417 (central nervous system development), GO:0007399 (nervous system development), GO:0048709 (oligodendrocyte differentiation), GO:0042063 (gliogenesis), GO:0014003 (oligodendrocyte development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Annexin (A0A8I5ZQ42)
Organism: Rattus norvegicus (Rat)
Function: Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis
InterPro domains:
- IPR037104: Annexin superfamily (homologous_superfamily) [125-463]
- IPR018502: Annexin repeat (repeat) [160-462]
- IPR001464: Annexin (family) [174-461]
- IPR018252: Annexin repeat, conserved site (conserved_site) [177-460]
Sequence:
MSYPGYPPTGYPPFPGYPPAGQESSFPTSGQYPYPSGFPPMGGGAYPPAPSGGYPGAGGYPSPGGYPAPGGYPGTLNPGGPPSYPGGQGFGAPPGGAGFSGYPQPPAQSYGGGPAQVPVPGGFPGGQMPSQYPGGQSPYPGQPAAMTQGTQGTIRPASNFDAMRDAEILRKAMKGFGTDEQAIVDVVSNRSNDQRQQIKAAFKTMYGKDLIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAIQGAGTQERVLIEILCTRTNQEIRDIVRCYQLEFGRELERDIRSDTSGHFERLLVSMCQGNRDESPSINHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYSMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFTQMYQKTLSTMIASDTSGDYRKLLLAIVGQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0008289 (lipid binding), GO:0005543 (phospholipid binding), GO:0005544 (calcium-dependent phospholipid binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0042221 (response to chemical), GO:0016043 (cellular component organization), GO:1901700 (response to oxygen-containing compound), GO:0010035 (response to inorganic substance), GO:0010033 (response to organic substance), GO:1902074 (response to salt), GO:0010038 (response to metal ion), GO:0051592 (response to calcium ion), GO:0014070 (response to organic cyclic compound), GO:0061024 (membrane organization), GO:0061025 (membrane fusion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0009986 (cell surface), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005576 (extracellular region), GO:0005615 (extracellular space), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Aldo-keto reductase family 1, member B10 (Aldose reductase) (M0R8B8)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR018170: Aldo/keto reductase, conserved site (conserved_site) [39-276]
- IPR020471: Aldo-keto reductase (family) [2-316]
- IPR036812: NAD(P)-dependent oxidoreductase domain superfamily (homologous_superfamily) [2-316]
- IPR023210: NADP-dependent oxidoreductase domain (domain) [17-292]
Sequence:
MAAFVKLSTKAKMPIVGLGTWKSPPDKVKEAVKAAIDAGYRHFDCAYVYQNESEVGEAIQEKIKEKAVRREDLFIVSKLWPTFFEKSLVKKAFQKTLLDLKLDYLDLYLIHWPQGFQSGNVFLPTDDKGNVLTSKYTFLDAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHSKGIVVTAYSPLGSPDRPSAKPEDPVLLEIPKIKEIASKHKKTAAQVLIRFHIERNVAVIPKSVTPSRIQENIQVFDFQLSEEDMAAILSFNRNWRACGLFAASRNEDFPFHSEY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:0008289 (lipid binding), GO:0097159 (organic cyclic compound binding), GO:0016491 (oxidoreductase activity), GO:1901363 (heterocyclic compound binding), GO:0043167 (ion binding), GO:1901265 (nucleoside phosphate binding), GO:0043168 (anion binding), GO:0019842 (vitamin binding), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0019840 (isoprenoid binding), GO:0000166 (nucleotide binding), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor), GO:0070401 (NADP+ binding), GO:0016918 (retinal binding), GO:0017076 (purine nucleotide binding), GO:0005501 (retinoid binding), GO:0070402 (NADPH binding), GO:0004033 (aldo-keto reductase (NADP) activity), GO:0030554 (adenyl nucleotide binding), GO:0008106 (alcohol dehydrogenase (NADP+) activity), GO:0050661 (NADP binding), GO:0052650 (NADP-retinol dehydrogenase activity), GO:0004032 (alditol:NADP+ 1-oxidoreductase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0009987 (cellular process), GO:0065008 (regulation of biological quality), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0042445 (hormone metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:0006629 (lipid metabolic process), GO:0120254 (olefinic compound metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0006066 (alcohol metabolic process), GO:0010817 (regulation of hormone levels), GO:0042572 (retinol metabolic process), GO:0006081 (cellular aldehyde metabolic process), GO:0006720 (isoprenoid metabolic process), GO:0019751 (polyol metabolic process), GO:0042574 (retinal metabolic process), GO:0034308 (primary alcohol metabolic process), GO:0006721 (terpenoid metabolic process), GO:0016101 (diterpenoid metabolic process), GO:0001523 (retinoid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Protein Wnt (A6I6F2)
Organism: Rattus norvegicus (Rat)
Function: Ligand for members of the frizzled family of seven transmembrane receptors
Subcellular location: Secreted, extracellular space, extracellular matrix
InterPro domains:
- IPR018161: Wnt protein, conserved site (conserved_site) [209-218]
- IPR005817: Wnt (family) [40-354]
- IPR043158: Wnt, C-terminal domain (homologous_superfamily) [294-354]
Sequence:
MRARPQVCEALLFALALHTGVCYGIKWLALSKTPAALALNQTQHCKQLEGLVSAQVQLCRSNLELMRTIVHAAREAMKACRRAFADMRWNCSSIELAPNYLLDLERGTRESAFVYALSAATISHTIARACTSGDLPGCSCGPVPGEPPGPGNRWGGCADNLSYGLLMGAKFSDAPMKVKKTGSQANKLMRLHNSEVGRQALRASLETKCKCHGVSGSCSIRTCWKGLQELRDVAADLKTRYLSATKVVHRPMGTRKHLVPKDLDIRPVKDSELVYLQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCGRGYNPYTDRVVERCHCKYHWCCYVTCRRCERTVERYVCK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0048869 (cellular developmental process), GO:0009991 (response to extracellular stimulus), GO:0030154 (cell differentiation), GO:0031667 (response to nutrient levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Peptidyl-prolyl cis-trans isomerase (A0A8I5ZN96)
Organism: Rattus norvegicus (Rat)
Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
InterPro domains:
- IPR020892: Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site (conserved_site) [82-99]
- IPR029000: Cyclophilin-like domain superfamily (homologous_superfamily) [24-212]
- IPR002130: Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain (domain) [41-198]
Sequence:
MSRGPRLLLPAVLFLGLGGLVSSSGSSGVRKRGPLVTDKVFFDVRIGDKDVGRIVIGLFGKVVPRTVENFVTLATGEKGYGYKGSIFHRVIKDFMIQGGDFTARDGTGGMSIYGETFPDENFKLKHYGIGWVSMANAGPDTNGSQFFITLTKPAWLDGKHVVFGKVLDGMTVVHSIELQATDDHDRPLTDCTIVNSGKIDVKTPFVVEVPDW
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0033218 (amide binding), GO:0042277 (peptide binding), GO:0016018 (cyclosporin A binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0046907 (intracellular transport), GO:0051649 (establishment of localization in cell), GO:0006810 (transport), GO:0051169 (nuclear transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0005790 (smooth endoplasmic reticulum), GO:0043231 (intracellular membrane-bounded organelle)