Protein: ATP-binding cassette sub-family G member 2 isoform X1 (A0A8M9PT70)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
- IPR003593: AAA+ ATPase domain (domain) [67-257]
- IPR043926: ABC transporter family G domain (domain) [238-296]
- IPR050352: ATP-binding cassette subfamily G transporters (family) [28-630]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [35-281]
- IPR013525: ABC-2 type transporter, transmembrane domain (domain) [370-580]
- IPR003439: ABC transporter-like, ATP-binding domain (domain) [33-281]
Sequence:
MADTRVELTGVLDLQNHVNTGVSSSPSRRGATVSFHNINYSLKMKSGFCKSKSTKKNILIGLNGIMKPGLNAILGATGSGKSSFLDVLAARKDPAGLSGEVLIDGAPQPPNFKCLSGYVVQDDVVMGTLTVRENLRFSAALRLPKSIKQREKDEKVERLIQELGLSKVADSRVGTQLIRGVSGGERKRTNIGMELIIDPPVLFLDEPTTGLDASTANSVLMLLKKMGNNGRTIILSIHQPRYSIYRLFDSLTLLVGGKLVYHGPAQDALSYFSQIGYTCEPHNNPADFFLDVINGDSSAVTLNKLYEEVVDQDQLSSSLKGIEDRLVEEYQRSSIFQQTHADLQRIVQGQDYSTRPKSRTITYSTSFCHQFHWVLKRTFRNLMLNPQTSVAQIGVMIFLALVVGAIFFGVAENSSGIQNRMGALFFITTNQCFSSVSAAELFIAERKLFVHEYISGYYRVSVYFLSKILSDILTLRTIPAVIFSCVAYFMIGLKPAAEAFFIFLFSIIMVSYTATAMTLAISADQTVVAIANIFMTISFVFMMIFSGLLVNLPSVATWLNWLKYFSIPRYGLSALQINEFTGLFFCDNRNNSGSVCSSGEEFLQEQGIDYSAWGLWQNHLALGIMTFIFLCIAYLKLRFIKKFT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015562 (efflux transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0051179 (localization), GO:0098754 (detoxification), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0055085 (transmembrane transport), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0051234 (establishment of localization), GO:0051716 (cellular response to stimulus), GO:0071704 (organic substance metabolic process), GO:1990748 (cellular detoxification), GO:0003008 (system process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0070887 (cellular response to chemical stimulus), GO:0007588 (excretion), GO:0006810 (transport), GO:0009636 (response to toxic substance), GO:0003014 (renal system process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0046415 (urate metabolic process), GO:0003013 (circulatory system process), GO:0003018 (vascular process in circulatory system), GO:0097237 (cellular response to toxic substance), GO:0071705 (nitrogen compound transport), GO:0070633 (transepithelial transport), GO:0097254 (renal tubular secretion), GO:0010232 (vascular transport), GO:0051180 (vitamin transport), GO:0071702 (organic substance transport), GO:0072521 (purine-containing compound metabolic process), GO:0042908 (xenobiotic transport), GO:0150104 (transport across blood-brain barrier), GO:0015711 (organic anion transport), GO:0032218 (riboflavin transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:1990351 (transporter complex), GO:0098797 (plasma membrane protein complex), GO:1902495 (transmembrane transporter complex), GO:0005886 (plasma membrane), GO:0098533 (ATPase dependent transmembrane transport complex), GO:0043190 (ATP-binding cassette (ABC) transporter complex)