lokahq/bioreason-rl huggingface dataset:
Protein: Solute carrier family 12 member 8 isoform X1 (A0A8M2BF89)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
- IPR004841: Amino acid permease/ SLC12A domain (domain) [42-415]
- IPR004842: SLC12A transporter family (family) [7-693]
Sequence:
MSPQVQELFHEDAQGSQINAQPWWKVQLFVWEPVLFGTWDGVFTTCMINIFGVVLFLRTGWLVGNTGVFLGMLLVSLVVLVALVTVMSGVGVSECCSVGNGGVYSMISTVLGGRIGGTVGLLYVFGQCVAGAMYITGFAESIAQVLSLQSTWVVRGISVAVLLGLLGINLAGVKWIVRLQLVLLGILAMSTLDFVIGTFSHLDPEHGFVGYSEKLLRKNTLPDYTAGETFFTVFGVFFPAATGVMAGFNMSSDLQRPEHNIPVGTLAAVCTSWFLYLVFVFLLGAICTREALRYDFLIAEKVSLVGFLFLLGLYISSLASCMGGLYGAPRILQCIAQERVIPVLAFLGKGRGPNKTPVAAICLTSLITMGFIFIGQVNVLAPIVTINFMLTYSVIDYCYFCVVKTYELQVQQRKKLISRSSSRKSLVSSTHPRYGSGGAISDPVNGTLLQFTKDMDQIFPLPSTEEQRASPASKARGRKTKIPAKEMLMNSFGLDLNSNAPLDKGKDERELEQAAGLDDDTSSQIGLIESDLKMGNQMNLSLPNSGPAELEQLPKEKIDRNGSETNLEGSEIRSIQSSVYARFCNPWVSLIGALCSFMIMFIIQWMYALINISAALILFIYIGTTSPGLPTGAASHFSFFKWLKTSLHNLGRQNGALQDQIVVTPSLSAVGMETRQLTEENADFALRDRYHHSSFITTTDKMVHPQSN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0008509 (monoatomic anion transmembrane transporter activity), GO:0015108 (chloride transmembrane transporter activity), GO:0015103 (inorganic anion transmembrane transporter activity), GO:0015267 (channel activity), GO:0022839 (monoatomic ion gated channel activity), GO:0005253 (monoatomic anion channel activity), GO:0022836 (gated channel activity), GO:0005254 (chloride channel activity), GO:0005244 (voltage-gated monoatomic ion channel activity), GO:0008308 (voltage-gated monoatomic anion channel activity), GO:0022832 (voltage-gated channel activity), GO:0005247 (voltage-gated chloride channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0006996 (organelle organization), GO:0030030 (cell projection organization), GO:0022607 (cellular component assembly), GO:0044782 (cilium organization), GO:0070925 (organelle assembly), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0060271 (cilium assembly), GO:0120031 (plasma membrane bounded cell projection assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Far upstream element-binding protein 1 isoform X3 (A0A8M3B6R5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR004087: K Homology domain (domain) [88-446]
- IPR048251: Far upstream element-binding protein 1, third type I KH domain (domain) [268-335]
- IPR004088: K Homology domain, type 1 (domain) [92-443]
- IPR036612: K Homology domain, type 1 superfamily (homologous_superfamily) [84-460]
- IPR015096: Far upstream element-binding protein, C-terminal (domain) [597-615]
- IPR048250: Far upstream element-binding protein 1, second type I KH domain (domain) [174-244]
- IPR048252: Far upstream element-binding protein 1, fourth type I KH domain (domain) [374-445]
Sequence:
MADYSNVAPPSSNAGGGMNDAFKDALQRARQIAAKIGGDGVPPSPVSNDFGYGGQKRPLEDGDQPETKKVPPSDPFSAVMGGMGGPPRSVSEEFKVPDGMVGFIIGRGGEQISRLQQESGCKIQIAPDSGGMPDRSVTLTGSPDAIMTAKRLLSEIVEKGRPSPAFHHNDGPGMSVHEMMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRISGDPFKVQQAKDMVMDLIRDQGFREQRGEYGSRAGGGGGGGESLDVPVPRFAVGIVIGRSGEMIKKIQNDTGVRIQFKPDDGSTPERIAQIMGPPDRAQHAADIITDLLRSVQAGGPPGHGGGGGGGGGGRGRGRGQGNWNMGPPGGLQEFTFTVPTMKTGLIIGKGGETIKNISQQSGARIELQRNPPPNSDPNIKIFTVRGSPQQIDYARQLVEEKIGGPVSPMGGPHGPPGPHGGPSHGPPGPQGPPAPMGPYNPGPYGQGPPGPHGPPAPYQPQGWGNGYPHWQQGQPDPNKAAADANAAAWAAYYSQYQQQPQGPMTPTSAAPGTTQANGQGQGQPQQDYTKAWEEYYKKQGQAAPQAAAAATATQPGGQPDYSAAWAEYYRQQAAYYGQGAPQAMGGAPQAQQGQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010468 (regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Band 4.1-like protein 3 isoform X8 (A0A8M9PFZ0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
Sequence:
MTTEPEGKAEQQGACAAPPHSAPPLDNQLPPAAAHSTPVKKDQAGEREVGGVPQGKPNQLSAEDDGSSHWSSSSKLNRSPAKISKKPKNMQCKITLLDGSDYTCVVEKRDKGQVLFDKVCEHLNLLEKDYFGITFRDVENQKNWLDPAKDMKKQIRGVAWNFSFNVKFYPPEPALLSEDITRYYLCLQLRDDISSGRLPCSFATHTVLGSYTVQSELGDHDPEECGSEYTSEFRFAPQQTKEMEEKIIDLHKNYKGMTPAEAEMHFLENVKKLSMYGVDLHHAKDSEGVEIMLGVCSSGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLVLPETPPKKFLTLGSKFRYSGRTQAQTRRASSQIVRPAPYFQRSSSKRYTMSRSLDGEMGTALYGAAKGIAMSDLITTVTPEKKVEEEPQPQKHTHADKQMQPQTETETETDTHTQTQTVLVENVMILEDDDETTRATELSLPSPATPARLDTRTDLTDTAVDGELTATESDQEDESEAKTKEADLTPDEQLKPQTNISELKRTFLEGGAEPAGLTEWEKRLSSSPLRSPRREEPPMIEPLELDEIKQEVVVETQEVAETQEVAAALDTQENNRKVDEPKPSFEEMSPELTALLQSARSWTPVPASASPSASASALVTPAPAALHTPQNQPSESVDEHLGKGLTEEERPADEPLDKPQTGVLSFRSVSGDTHDTHETHDTPVIQTEIKTITYEALQAETDGDADPGVLMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVISGDADIDHDEALAQAIKEAKEQHPDMSVTKVVVHKETEITPEEAEE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0065008 (regulation of biological quality), GO:0050794 (regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0050803 (regulation of synapse structure or activity), GO:0044087 (regulation of cellular component biogenesis), GO:0050807 (regulation of synapse organization), GO:1901888 (regulation of cell junction assembly), GO:0051963 (regulation of synapse assembly), GO:1904889 (regulation of excitatory synapse assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0098794 (postsynapse), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0045202 (synapse), GO:0005886 (plasma membrane), GO:0099572 (postsynaptic specialization), GO:0098984 (neuron to neuron synapse), GO:0014069 (postsynaptic density), GO:0032279 (asymmetric synapse)
Protein: DNA-binding protein Ikaros isoform X2 (A0A8M2B2N6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR050589: Ikaros C2H2-type zinc-finger (family) [145-623]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [241-623]
- IPR013087: Zinc finger C2H2-type (domain) [227-628]
Sequence:
MAASDGLLGVSFYWHDTKRSAKLCCLDSPSRFGLWNKSLQNVSHEHRDIAMLGWKEEVQWRGEGPRAEFQTAAAALKTCAHGAAGDSWKSFILQTQGIAEYLHRMETEEAQEMSQITGRDSPMNANEGGEDQDEAMPVPEDLSASTGLQHNNRTDKPLACNIKVEARSDEENGLSCEMNGEAEECAAEDLRILDGSGAKVNGSHAGPDSKPAAYPTAGGIRLPNGKLKCDICGIVCIGPNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSVGKPHKCAYCGRSYKQRSSLEEHKERCHNYLQCMGLQNSIYTVKEENSQNEQREDMPASERALVLDRIANNVAKRKSSMPQRFVGENRLSELSFESGSGELMQPHVIDQAINSAISYLGAESLRPLVQTSPGSADMVVSPLYNLHKSQTAEGNGVSAKDSAAEHLLLLSKSKSASVDKDGSPSPSGQDSTDTESNNEERSAGVSGTAATGGLIYLTNHMAPGMRNGGLPGVKEEQHRQFEALRAAGMDLSIASSEGFKVLSGDGEELRAYRCIHCRVLFLDHVMYTIHMGCHGFRDPFECNLCGYRSQDRYEFSSHITRGEHRI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0001775 (cell activation), GO:0045321 (leukocyte activation), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0046649 (lymphocyte activation), GO:0030097 (hemopoiesis), GO:0042110 (T cell activation), GO:0002521 (leukocyte differentiation), GO:0030098 (lymphocyte differentiation), GO:0042113 (B cell activation), GO:1903131 (mononuclear cell differentiation), GO:0030217 (T cell differentiation), GO:0030183 (B cell differentiation), GO:0033077 (T cell differentiation in thymus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex)
Protein: Nuclear pore complex protein Nup153 isoform X1 (A0A8N7TFJ5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR001876: Zinc finger, RanBP2-type (domain) [633-848]
- IPR013913: Nucleoporin Nup153, N-terminal (domain) [98-603]
- IPR036443: Zinc finger, RanBP2-type superfamily (homologous_superfamily) [634-847]
- IPR026054: Nuclear pore complex protein (family) [4-814]
Sequence:
MAATGGGKIRSRRHHIASKPYAKGKQQPGLITRVTDTVKSIVPSWLQKYFRNGEGPEGGASAAGVEHNNMTPPPNGSDEAPLRDGRDSPEPSTSNTEPSTSRASLNFQEALSRPPLNRTHLQFPSLDGSPALGGSSSLFSQPSTSTAPFSGSPFAVTSNFSLVKEIKDSSSQHEDDNISTTSGFSSRASDKDVPTSKTVPLLWSPETERTHSGSQTAHSGLKKPAFNLSVFGTSSSSVLNSSVLNSSQLGDSPFYPGKTTYGGASAMRTARSRPATPYQPPVRRQIKAKPTGAQPCGVTSATARRILQSLERMSSPLADAKRIPSTVSSPLSASLNHTDLDISNYQAKRKRLEPSVPPVQKLVVPAAAAVSGNRSISFRPSLTPGGVSRGVEKTSRETPVRQSPPISEPAQAPPPSTSTLSYPLSSTPAANSAALGGGKMKRERAIRPSSKRPDDEVAEEPDLPPASLPSNFTLPTFTFSTPPPTSSLKSSTAPLITVSEEPAANKPAAPSTPPSAPFTFSSPIVKATAASPPSFSPSSGFTFSAPTMKMGPSFSNGKIVPSVAPVKSVVIEEKEFEGPFKPAKVLKQGSVLDILKGPGFASPSQNSTDKPLQSTSTTTSSPFSGFGDKFRPPAGSWNCGTCMLQNKPSDKKCVACLAPQPNTDSSKSDSKPAEAPASISSLFAPPAGSWECDTCLVSNKPDAVKCVACDTAKPGTGVKSSLTLLAASESSSSTTTTATTTAAALTSTGLLGLGDKFKKPEGAWDCDVCMVQNKAQDLKCVACLTAKPGAAAAPLSTPASAPVSSAAPLLGFGDKFKKPEGSWECDVCCVQNKADDQQCVACQSAKPGAKIESKGFSSSFGVQSNSTDSNTSGFKFGTGSTDSSSSSAGLKFGGTFSDSSTTGGIKFGFGLSSTSSEGFKFGGSSSDAGGAKLSSTLSESTATKESSTKSFAFGGSADDTLEKKSKTQESNTGFKFGGGSGMASGSENSSFLFGAKPSEKGSSNPSFSFPVPQSKVEKDAPSETPPVSNTTTTTTAANALPVFGKSLVAESSAPKFGEPATKEQTLVTSTFTFGKPEEKKDTSAPSSTFLFGSSKEAEKPTPNLGFAFSEPDPPKDFPKPALTFGKPAESTEPPKPSFGFGQSLTETSAPKPSFGFMANSTSSTPASSSSTPSLFGTPTTSSLAPTPAPTSTFVFGQNSSSELNVGKTFVFGQQQQDSQPAPPAAPSAAPAQPFQFGSGSNSSTPSFTFGAAASSTPASAAPAPSANPSPFVFSSAAPSSGFGSGQTPIFGQSASQPSAPAFGSAAPSFSASATPASTFGAKPSSAPVFGQQANAAPTFGSTAASTGQGGFQFGSTGGFGASATSNSVFNFGGGSAAPAASPAMPALNPPAGGGFGFSPTPAFNIGSAKSSFTASPAGQNSIAGRKIKTAVRRRK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0035239 (tube morphogenesis), GO:0048514 (blood vessel morphogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000785 (chromatin), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome)
Protein: RNA helicase (A0A8M9QJS4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm
InterPro domains:
- IPR001650: Helicase, C-terminal domain-like (domain) [537-698]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [258-703]
- IPR011545: DEAD/DEAH-box helicase domain (domain) [322-513]
- IPR014014: RNA helicase, DEAD-box type, Q motif (domain) [298-326]
- IPR000629: ATP-dependent RNA helicase DEAD-box, conserved site (conserved_site) [468-476]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [317-541]
Sequence:
MSHVVVDGSHGLDQQLAVLDLNSADGQGVGTGRRYIPPHLRNKDASKNAGNAYSSGRQSGYSVAPVQSFSPKQYPQSWHPEGNQRHRQNYPTGWNDFRTGSQRFASQELAFYHTYTSGWPDRCDSPGWDGSRTNGFVNGYHDSRMNGTANFARGPLRNDRGGRGGFRGNRNGASFNQPVHNAGYGTYENKDGGWNSVVNRDAYASFGGRSDRGKSAFFNDRGASSRGRYERGGFGGGTGGNSRWVEESRDEEDWSKPMPPNERLEHELFSASNTGINFEKYDDIPVEATGTNSPGHIESFHDVDMGEIIMGNITLSRYTRPTPVQKYAIPIIKTKRDLMACAQTGSGKTAAFLLPVLSQIYSEGPGEALQATKASTQQENGKYVRRKQYPISLVLAPTRELALQIYDEARKFAYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDYCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGSRQTMMFSATFPKEIQILARDFLEEYIFLAVGRVGSTSENITQKVVWVEENDKRSFLLDLLNATGKDSLTLVFVETKKGADALEDFLYREGYACTSIHGDRSQRDREEALHQFRSGRCPIMVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFYNDKNSNITKDLLDILVEAKQEVPSWLENLAYEHQHKSTNRGRPKRFSGGFGARDYRQMPGGGNTFGNRGARNTGGHGGNRGFGGNKGGFGSFGGDSYGGTYGNYGGNYTQVDWWGN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0048870 (cell motility), GO:0042221 (response to chemical), GO:0050900 (leukocyte migration), GO:0042330 (taxis), GO:0097529 (myeloid leukocyte migration), GO:0006935 (chemotaxis), GO:0030595 (leukocyte chemotaxis), GO:0070887 (cellular response to chemical stimulus), GO:0016477 (cell migration), GO:0071621 (granulocyte chemotaxis), GO:0060326 (cell chemotaxis), GO:0097530 (granulocyte migration), GO:1990266 (neutrophil migration), GO:0030593 (neutrophil chemotaxis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0043229 (intracellular organelle), GO:0035770 (ribonucleoprotein granule), GO:0036464 (cytoplasmic ribonucleoprotein granule), GO:0045495 (pole plasm), GO:0043228 (non-membrane-bounded organelle), GO:0043186 (P granule), GO:0060293 (germ plasm), GO:0043232 (intracellular non-membrane-bounded organelle)
Protein: Bromodomain-containing protein 3 isoform X3 (A0A8M2B853)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR001487: Bromodomain (domain) [28-401]
- IPR050935: Bromodomain-containing chromatin reader (family) [7-657]
- IPR036427: Bromodomain-like superfamily (homologous_superfamily) [14-406]
- IPR043508: Brdt, bromodomain, repeat I (domain) [30-136]
- IPR018359: Bromodomain, conserved site (conserved_site) [52-374]
- IPR027353: NET domain (domain) [542-624]
- IPR043509: Brdt, bromodomain, repeat II (domain) [295-396]
- IPR038336: NET domain superfamily (homologous_superfamily) [544-624]
Sequence:
MSAVTSATPEPPAAANPPPPEVINPTKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAVKLGLPDYHKIIKNPMDMGTIKKRLESVYYYSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVALMPQEEVELLPPAPKGKGRKPAGPGQQDGAVSTGSPTSVFPGATSPSSQTAVVSPAPVPAITPSIPAVQNTTAAAVIPSMPPSQPTVKKKGVKRKADTTTPTTSAITASRSQSPTPILEGKQSKVAARRESTGRPIKPPKKDFEDGELGVHGGKKGRLSEQLKYCDVILKEMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKKKMDSREYQDAQTFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPVEVPGAGGVGGAGVVSKSTVSSESSGDSSTSDSSDSEEERATRLAELQEQVGAEQLKAVHEQLAALSQAPVSKPKKKKEKKEKDKKKKENKHNKSKPEEKAKPGQPPKPAQQKKGPTRKANSTVPGNRQPKKGGRGPGYESDEEMSLPMTYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPSTLRELERYVKSCLQKKQRKPPQKGGSGPSRLSGSSSSSDSGSSSSSGSTSDSSDSD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding), GO:0005515 (protein binding), GO:0042393 (histone binding), GO:0140030 (modification-dependent protein binding), GO:0140033 (acetylation-dependent protein binding), GO:0070577 (lysine-acetylated histone binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0030154 (cell differentiation), GO:0048468 (cell development), GO:0030097 (hemopoiesis), GO:0030099 (myeloid cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus), GO:0005694 (chromosome), GO:0000793 (condensed chromosome)
Protein: Septin (A0A8M3ATV2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, cilium axoneme
InterPro domains:
- IPR016491: Septin (family) [1-378]
- IPR008115: Septin 7 (family) [180-392]
- IPR030379: Septin-type guanine nucleotide-binding (G) domain (domain) [1-264]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [1-265]
Sequence:
MVVGESGLGKSTLINSLFLTDLYSGEYPGPSNRIKKTVQVEQSKVLMKEGGVQLLLSIVDTPGFGDAVDNSNCWQPVIDHIDSKFEDYLNAESRVNRRQMPDSRVHCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMREILEHKIKIYEFPETDDEEENKIVKTIKDRLPLAVVGSNTIIEANGKKVRGRQYPWGVAEVENGDHCDFTLLRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTCNGIDNNKAKGQLTKVDTVEGMSPLAQMEEERREHVTKMKKMEMEMEQVFEMKVKEKVQKLKDSEGELQRRHEQMKKNLEAQHKELEERRRQFEEERSTWETQQRILEQQKMYVMTLEKNKKKGKIF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016462 (pyrophosphatase activity), GO:0017111 (ribonucleoside triphosphate phosphatase activity), GO:0003924 (GTPase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0042742 (defense response to bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle)
Protein: Signal peptide peptidase-like 2B isoform X1 (A0A8M9QFX8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein; Lumenal side
InterPro domains:
- IPR003137: PA domain (domain) [68-143]
- IPR007369: Peptidase A22B, signal peptide peptidase (family) [44-420]
- IPR006639: Presenilin/signal peptide peptidase (family) [210-459]
- IPR046450: PA domain superfamily (homologous_superfamily) [79-152]
Sequence:
MRFLSSLLLAALIVEQVLGEYGMAHFSDWGNSKGKDYCIFFNSQWARLPQDLSKATRLQTYDLTSSVLCSPSDVPEGGFPNSIPMVMRGNCTFYEKVRLAQINGAKGLLIVSKDRLTPPSGNKSQYEEIGIPVALLSYKDMLDISKTFGEKRQVAMYAPNEPVVDYNMVLIFLMAVGTVALGGYWAGSRDIKKRYMKHKRDDGAEKQDEETVDVTPIMICVFVVMCCSMLVLLYFFYDQLVYMTIATFCLASAVSLYSCLWPFVRRIPFGKCRIPENNLPYCHKRPQVRMLILSAFCIGVSVTWGVFRNEDQWAWILQDALGIAFCLYMLKTIRLPTFKACTLLLVVLFVYDVFFVFITPLLTKSGESIMVEVAAGPSDSSTHEKLPMVLKVPRLNSSPLVLCDRPFSLLGFGDILVPGYGIGLLITFVALTLMQMGQPALLYLVPCTLLTSLAVALWRKELPLFWTGSGFVPPPIIMEQINCTQTPGPSTDEPPSNPEPATSETNNQREDPTPATQEEVPHLTDASNT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0004175 (endopeptidase activity), GO:0070001 (aspartic-type peptidase activity), GO:0004190 (aspartic-type endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0065007 (biological regulation), GO:0051241 (negative regulation of multicellular organismal process), GO:0051239 (regulation of multicellular organismal process), GO:0050819 (negative regulation of coagulation), GO:0050818 (regulation of coagulation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)