lokahq/bioreason-rl huggingface dataset:
Protein: RCG49295, isoform CRA_x (A6J3A5)
Organism: Rattus norvegicus (Rat)
Function: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain
Subcellular location: Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein
InterPro domains:
- IPR050174: Protocadherin/Cadherin-related Cell Adhesion (family) [15-821]
- IPR031904: Cadherin, C-terminal catenin-binding domain (domain) [810-862]
- IPR013164: Cadherin, N-terminal (domain) [30-112]
- IPR032455: Cadherin, cytoplasmic C-terminal domain (domain) [687-771]
- IPR020894: Cadherin conserved site (conserved_site) [230-560]
- IPR015919: Cadherin-like superfamily (homologous_superfamily) [29-666]
- IPR002126: Cadherin-like (domain) [27-683]
Sequence:
MAAPARRPHCTRLVLLCALLGMLWEARARQIHYSVPEETEKGYTVGNISKDLGLEPRELAERGVRIISKGKTQFFSLSPRSGCLVTAGRIDREELCARIAPCVLSFKVLVEDRVKLYGVEVEVIDINDNAPKFEAENLVVKISEIAAPGARYPLPEAVDPDVGINSLQSYQLSPNRHFSLDIQRGDDGTINPELVLERTLDREEEPSHHLVLTASDGGDPRRSSTALIQVTVLDTNDNAPAFDQPVNRVKVLENVAPGTLLLTVRASDPDEGANGKVTYKFRKMNEKQSLLFHLHENTGEMTVAKTLDYEECSLYEMEIQAEDGGGLKGRTKVVVTVEDVNDNRPEVTITSLFSPVREDAPPGTVIVLFNAHDQDSGKNGQVVCSIQENPSFKLENSVDDYYRLMTAQILDREKASEYNITVTATDRGTPSMSTEVQITLYVADINDNPPAFSQTSYSVYLPENNPRGTSIFSVSAHDPDENENAKVTYSLVENTIQGAPLTSYISINSDTGVLYALQSFDYEQFRNLQMQVKASDSGHPPLSSNVSLSVFLLDQNDNAPKILYPSLPTDGSTGVELAPRSAEAGYLVTKVVAVDEDSGQNAWLSYRLLKASEPGLFTVGLRSGEVRTARALLERDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPDILADLSSISTPADPDSDITLYLVVAVAVVSCVFLLFVLVLLALRLRRWHASSLLQDAIGGSTGVPTSHIVGVHGVQTFLQTYSQEFSLTPDSGKSHLIFPQPNYADTLISQESCGKSEPLCSSVESKFPIDDTPLVPQAPPNTDWRFSQAQRPGTSGSQNGDETGTWPNNQFDTEMLQAMILASASEAADGTLPVLTSL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0019953 (sexual reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0007276 (gamete generation), GO:0007283 (spermatogenesis), GO:0048232 (male gamete generation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)
Protein: Xeroderma pigmentosum, complementation group A (Predicted), isoform CRA_b (A6IJB3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR037129: XPA domain superfamily (homologous_superfamily) [98-208]
- IPR022656: XPA, C-terminal (domain) [135-186]
- IPR022658: XPA, conserved site (conserved_site) [138-154]
- IPR022652: Zinc finger, XPA-type, conserved site (conserved_site) [103-133]
- IPR000465: XPA/RAD14 (family) [17-273]
- IPR009061: Putative DNA-binding domain superfamily (homologous_superfamily) [134-207]
Sequence:
MATAEEKRTSPEPAAAEKPAELPAAVRASVERKRQRALMLRQARLAARPYPAAAATGGVTSIKAAPKVIDTKGGFILEEEEEEKHKIGDVVHEPGPVMEFDYTICEECGKEFMDSYLMNHFDLPTCDSCRDADDKHKLITKTEAKQEYLLKDCDLEKREPALRFIVKKNPRHSQWGDMKLYLKLQVVKRALEVWGSQEALEDAKEVRQENREKMKQKKFDKKVKELRRAVRSSVWKRETTAHQHEYGPEEHLEEDMYRKTCTLCGHELTYEKM
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003684 (damaged DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0009612 (response to mechanical stimulus), GO:0010996 (response to auditory stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Tial1 cytotoxic granule-associated RNA binding protein-like 1 (Mapped), isoform CRA_b (A6IA07)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR034492: TIAR, RNA recognition motif 1 (domain) [10-90]
- IPR000504: RNA recognition motif domain (domain) [9-123]
- IPR035979: RNA-binding domain superfamily (homologous_superfamily) [7-123]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [1-124]
Sequence:
MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKIS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0010941 (regulation of cell death), GO:0010942 (positive regulation of cell death), GO:0043067 (regulation of programmed cell death), GO:0043068 (positive regulation of programmed cell death), GO:0043065 (positive regulation of apoptotic process), GO:0042981 (regulation of apoptotic process), GO:1904037 (positive regulation of epithelial cell apoptotic process), GO:1904035 (regulation of epithelial cell apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0035770 (ribonucleoprotein granule), GO:0036464 (cytoplasmic ribonucleoprotein granule), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0010494 (cytoplasmic stress granule), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005634 (nucleus)
Protein: RCG32429 (A6JX66)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR036645: Elafin-like superfamily (homologous_superfamily) [24-75]
- IPR008197: WAP-type 'four-disulfide core' domain (domain) [29-76]
Sequence:
MKLLSLPLLTVTILLCCNMAQAIFWRKKALSKPGFCPEFHLPCPFVLVPKCRRDRGCSGSLKCCFYYCQMRCVVPWDNSD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140678 (molecular function inhibitor activity), GO:0061134 (peptidase regulator activity), GO:0004857 (enzyme inhibitor activity), GO:0061135 (endopeptidase regulator activity), GO:0030414 (peptidase inhibitor activity), GO:0004866 (endopeptidase inhibitor activity), GO:0004867 (serine-type endopeptidase inhibitor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0042742 (defense response to bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: RAB6B, member RAS oncogene family (Predicted) (A6I2I4)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR050227: Ras-related protein Rab (family) [1-149]
- IPR001806: Small GTPase (family) [1-175]
- IPR005225: Small GTP-binding domain (domain) [5-136]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [1-173]
Sequence:
MYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQRAKELSVMFIETSAKTGYNVKQLFRRVASALPGMENVQEKSKEGMIDIKLDKPQEPPASEGGCSC
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0097367 (carbohydrate derivative binding), GO:1901265 (nucleoside phosphate binding), GO:0043168 (anion binding), GO:0000166 (nucleotide binding), GO:0032553 (ribonucleotide binding), GO:0035639 (purine ribonucleoside triphosphate binding), GO:0032555 (purine ribonucleotide binding), GO:0017076 (purine nucleotide binding), GO:0005525 (GTP binding), GO:0019001 (guanyl nucleotide binding), GO:0032561 (guanyl ribonucleotide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0035556 (intracellular signal transduction), GO:0007264 (small GTPase mediated signal transduction), GO:0007265 (Ras protein signal transduction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098793 (presynapse), GO:0030054 (cell junction), GO:0045202 (synapse)
Protein: Mediator of RNA polymerase II transcription subunit 10 (A6JV08)
Organism: Rattus norvegicus (Rat)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors
Subcellular location: Nucleus
InterPro domains:
- IPR019145: Mediator complex, subunit Med10 (family) [9-125]
Sequence:
MAEKFDHLEEHLEKFVENIRQLGIIVSDFQPSSQAGLSQKLNFIVTGLQDIDKCRQQLHDITVPLEVFEYIDQGRNPQLYTKECLERALAKNEQVKGKIDTMKKFKSLLIQELSKVFPEDMAKYRSIRGEDHPPS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity), GO:0061659 (ubiquitin-like protein ligase activity), GO:0061630 (ubiquitin protein ligase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0070647 (protein modification by small protein conjugation or removal), GO:0032446 (protein modification by small protein conjugation), GO:0016567 (protein ubiquitination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0140535 (intracellular protein-containing complex), GO:1990234 (transferase complex), GO:0000151 (ubiquitin ligase complex)
Protein: RCG61914, isoform CRA_b (A6HAN5)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR010394: 5-nucleotidase (family) [230-572]
Sequence:
MSQTSLKTKKKNEPGMRYSKESLDAEKRKDSDKSGARLSTQGSQEIPVPNTDSRGYVVRNQWSRTSRSPSTRAPSVDENRSRNTVVKAPNSSANSRTSSASASQHETSTSPPPQVSEKSPVQQPSPQTRTITPLDSQPPTPPETEPDSRRTSKMYTATDPWAHRDNREPRDLQLREYAHSCDSREGIPKTREYPRTPPTEWKSYVQRRLQYGSSVDMDPDCLPDGQHHRQKQQIEEDEVDEAYWSSVSMLYEKIPSCTRPRPPKPKHAITIAVSSRALFNMVDDRKIYEEEGLEKYMEYQLTNENVILTPGPAFRFVKALQHVNSRLRDLYPDEQDLFDIVLMTNNHAQVGVRLINSVNHYGLLIDRFCLTGGKSPIGYLKAYLTNLYLSADSEKVQEAIKEGIASATMFAGAKDMAYCDTQLRVAFDGDAVLFSDESEHIAKDHGLDKFFQHETLFENKPLAQGPLKGFLEDLGKLQKKFYAKDERLLCPIRTYLVTARSAASSGARVLKTLRRWGLEIDEALFLAGAPKGPILVKIRPHIFFDDQMFHIEAAQKFGTITAHVPYGIAQKRN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0016791 (phosphatase activity), GO:0008252 (nucleotidase activity), GO:0008253 (5'-nucleotidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:1901657 (glycosyl compound metabolic process), GO:0072521 (purine-containing compound metabolic process), GO:0009116 (nucleoside metabolic process), GO:0009119 (ribonucleoside metabolic process), GO:0042278 (purine nucleoside metabolic process), GO:0046128 (purine ribonucleoside metabolic process), GO:0046085 (adenosine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Similar to KIAA0869 protein (Predicted) (A6HDJ2)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR057747: WWC1-like, helical hairpin (domain) [119-252]
- IPR000008: C2 domain (domain) [482-607]
- IPR037771: WWC, C2 domain (domain) [484-607]
- IPR051105: WWC/KIBRA Hippo Pathway Regulators (family) [65-842]
- IPR035892: C2 domain superfamily (homologous_superfamily) [482-614]
Sequence:
MVHLQHELQFKERGFQTLKKIDERMSDAQGGYKLDEAQAVLRETKAIKKAITCGEKEKQDLIKSLAMLKDGFRTDRGSHSDLWSSSSSLESSSFPVPKQFLDVSSQTDISGSFSTSSSNQLAEKVRLRLRYEEAKRRIANLKIQLAKLDSEAWPGVLDSERDRLILINEKEELLKEMRFISPRKWTQGEVEQLEMARRRLEKDLQAARDTQSKALTERLKLNSKRNQLVRELEEATRQVAALHSQLKSLSSSMQSLSSGSSPGSLTSSRGSLAASSLDSSTSASFTDLYYDPFEQLDSELPSKVELLFLEGATGFRPSGCITTIHEDEVAKTQKAEGGSRLQALRSLSGTPRSMTSLSPRSSLSSPSPPCSPLIADPLLAGDAFLTPLEFEDTELSPTLCELSLGTDGARERFRLEEPGPEGKPLGQAASVAPGCGLKVACVSAAVSDESVAGDSGVYEASMQRLGTSEAAAFDSDESEAVGVTQVQIALKYDEKSKQFAILVIQLSNLSALLLQQDQKVNIRVAILPCSESSTCLFRTRPLDSADSLVFNEAFWVSMSYPALHQKTLRVDVCTTDRSHTEECLGGAQISLAEVCRSGERSTRWYNLLSYKYLKKQGREPQPAEAPGPDHVDAVSALLEQTAVELEKRQEGRSSSQTLEGSWTYEEEASENEAVAEEEEREEEEGEEDVFAEKVSPEAEECPALKVDRETNTDSVTPSPTVVRPKDRRVGAPSPGPFLRGNTIIRSKTFSPGPQSQYVCRLNRSDSDSSTLSKKPPFVRNSLERRSVRMKRPSSVKSLRTERLIRTSLDLELDLQATRTWHSQLTQEISVLKELKEHLEQAKNHGEKELPQWLREDERFRLLLRMLEKRVDRGEHKSELQADKMMRAAAKDVHRLRGQSCKEPPEVQSFREKMAFFTRPRMNIPALSADDV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0048870 (cell motility), GO:0016477 (cell migration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: RCG24403, isoform CRA_b (A6K534)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR038043: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D 3, SWIB domain (domain) [265-338]
- IPR036885: SWIB/MDM2 domain superfamily (homologous_superfamily) [253-343]
- IPR019835: SWIB domain (domain) [259-338]
- IPR003121: SWIB/MDM2 domain (domain) [258-335]
Sequence:
MAADEVAGGARKATKSKLFEFLVHGVRPGMPSGARMPHQGAPMGPPGSPYMGSPAVRPGLAPAGMEPARKRAAPPPGQSQAQGQGQPVPTAPARSRSAKRRKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNPAKPDAEDSDGSIASWELRVEGKLLDDPSKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTPTTQETDGFQVKRPGDLSVRCTLLLMLDYQPPQFKLDPRLARLLGLHTQSRSAIVQALWQYVKTNRLQDSHDKEYINGDKYFQQIFDCPRLKFSEIPQRLTGLLLPPDPIVINHVISVDPSDQKKTACYDIDVEVEEPLKGQMSSFLLSTANQQEISALDSKIHETIESINQLKIQRDFMLSFSRDPKGYVQDLLRSQSRDLKVMTDVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQRRQELEQSLVVRNT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0050793 (regulation of developmental process), GO:0051094 (positive regulation of developmental process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0051726 (regulation of cell cycle), GO:0045597 (positive regulation of cell differentiation), GO:0045595 (regulation of cell differentiation), GO:0090068 (positive regulation of cell cycle process), GO:0010564 (regulation of cell cycle process), GO:0045787 (positive regulation of cell cycle), GO:0051149 (positive regulation of muscle cell differentiation), GO:0007346 (regulation of mitotic cell cycle), GO:0045931 (positive regulation of mitotic cell cycle), GO:1901989 (positive regulation of cell cycle phase transition), GO:0051147 (regulation of muscle cell differentiation), GO:1901987 (regulation of cell cycle phase transition), GO:1902749 (regulation of cell cycle G2/M phase transition), GO:1902751 (positive regulation of cell cycle G2/M phase transition), GO:0051152 (positive regulation of smooth muscle cell differentiation), GO:1901992 (positive regulation of mitotic cell cycle phase transition), GO:1901990 (regulation of mitotic cell cycle phase transition), GO:0051150 (regulation of smooth muscle cell differentiation), GO:0010389 (regulation of G2/M transition of mitotic cell cycle), GO:0010971 (positive regulation of G2/M transition of mitotic cell cycle)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Fucokinase (Predicted) (A6IZ73)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR020568: Ribosomal protein uS5 domain 2-type superfamily (homologous_superfamily) [706-901]
- IPR052203: GHMP Kinase-Related Enzymes (family) [1-921]
- IPR036554: GHMP kinase, C-terminal domain superfamily (homologous_superfamily) [921-999]
- IPR006204: GHMP kinase N-terminal domain (domain) [817-890]
- IPR012887: GDP-fucose pyrophosphorylase domain (domain) [82-496]
Sequence:
MDQPKGVNWTVIILTCQYKDSVQVFQRELEVRQKREQIPAGTMLLAVEDPQTRVGSGGATLNALLVAAEHLSARAGFTVVTSDVLHSAWILILHMGRDFPFDDCGRAFTCLPVENPQAPVEALVCNLDCLLDIMTHRLGPGSPPGVWVCSTDMLLSVPPNPGISWDGFRGTRVIAFPGSLAYALNHGVYLTDSQGVVLDIYYQGTKAEIQRCVRPDGLVPLVSGVVFFSVETAEHLLATHVSPPLDACTYMGLDSGAQPVQLSLFFDILLCMARNMSRENFVAGRPPEMGQGDPDVARYLKGARAQLWRELRDQPLTMVYVPDGGYSYMTTDATEFLHRLTMPGVAVAQIVHSQVEEPQLLEATCSVVSCLLEGPVHLGPRSVLQHCHLRGPIHIGAGCFVSGLDTAHSEALHGLELHDLILQGHHIRLHGSQSRVFTLAGRLDSWERQGAGMYLNMSWNEFFKKTGIRDWDLWDPDTPLSDRCLLSARLFPVLHPTRALGPQDVLWMLHPHKDRGEALRAWRASWRLSWEQLQPRLDRAATLDFRRDLFFRQALQKARHVLEARQDLCLHPLIRAAVGEGCSGPLLATLDKVAAGAEDPGVAARALACVADVLGCMAEGQGGLRSGPAANPEWIQPFSYLERGDLMRGVEALAQEREKWLTRPALLVRAARHYEGAEQILIRQAVMTARHFVSTQPVELPAPGQWVVTECPARVDFSGGWSDTPPIAYELGGAVLGLAVRVDGRRPIGAKARRILEPELWLAVGPRQDEMTVKIVCRSLDDLQDYCQPHAPGALLKAAFICADIVHVNSEVPLHEQLLRSFNGGFELHTWSELPHGSGLGTSSILAGAALAALQRAAGRTVGTEALIHAVLHLEQVLTTGGGWQDQVSGLMPGIKVGRSRAQLPLKVEVEEITVPENFVQRKLMAPGCEPLAVHRMMDVLAPYAFGQSLAGAGGGGFLYLLTKEPRQKEVLEAVLAKVEGLGNYSVHLVQVDTQGLSLQLLGHDAHLCGAGPSEVGNT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:1901698 (response to nitrogen compound), GO:0010033 (response to organic substance), GO:1901700 (response to oxygen-containing compound), GO:0071869 (response to catecholamine), GO:0014070 (response to organic cyclic compound), GO:0010243 (response to organonitrogen compound), GO:1903350 (response to dopamine), GO:0071867 (response to monoamine)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: RING-type E3 ubiquitin transferase (A6IUN3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Multi- pass membrane protein. Peroxisome membrane; Multi-pass membrane protein
InterPro domains:
- IPR017907: Zinc finger, RING-type, conserved site (conserved_site) [286-295]
- IPR006845: Pex, N-terminal (domain) [16-240]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [239-324]
- IPR025654: Peroxisome biogenesis factor 2/10 (family) [3-323]
- IPR001841: Zinc finger, RING-type (domain) [270-309]
Sequence:
MAQAGPPEVIRAAQKDEYYLGGLRSAAGGALHSLAGAKKWLEWRKEIELLSDIAYFGLTTIAGYQTLGEEYVGIIQVDPSRQRVPSRLRRGVLVALHAVLPYLLDKALLPLEQELQAEGDGTRASQGSLLPGGRSRSGARRWVRHHAATLTEQQRRALQRAVFILRQGFACLHRLHVAWFYIHGTFYHLAKRLAGITYLRTRRLPGEDLRACTSYRLLGLISLLHLALSLGLQLYSFRQKQRARKEWRLHRNLSHRRSSLEDRAVCRAPLCTLCLEERRHSTATPCGHLFCWECITEWCNTKTECPLCREKFPPQKLVYLRHYR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity), GO:0061659 (ubiquitin-like protein ligase activity), GO:0061630 (ubiquitin protein ligase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0007031 (peroxisome organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0031090 (organelle membrane), GO:0042579 (microbody), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0031903 (microbody membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0005777 (peroxisome), GO:0005778 (peroxisomal membrane)