Protein: Transient receptor potential cation channel, subfamily C, member 5 (A6ZIF3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
- IPR002153: Transient receptor potential channel, canonical (family) [5-788]
- IPR005461: Transient receptor potential channel, canonical 5 (family) [270-966]
- IPR005821: Ion transport domain (domain) [376-635]
- IPR002110: Ankyrin repeat (repeat) [39-170]
- IPR036770: Ankyrin repeat-containing domain superfamily (homologous_superfamily) [20-308]
- IPR013555: Transient receptor ion channel domain (domain) [176-238]
Sequence:
MAQLYYKKVNYSPYRDRIPLQIVRAETELSAEEKAFLSAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYRKPSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELEIILNHRDDHSEELDPQKYHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFMLLLASQHIVRTDLHVQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSRPREEWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETRAIDEPNNCKGIRCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFNNTFCPKRDPDGRRRRHNLRSFTERHADSLIQNQHYQEVIRNLVKRYVAAMIRNSKTNEGLTEENFKELKQDISSFRYEVLDLLGNRKHPRRSFSTSSAEFSQRDDTNDGSGGARAKSKSVSFNLGCKKKACQGAPLIRTMPRASGAQGKPKAESSGKRSFMGPSFKKLGLLFSKFNGQTSEPTSEPMYTISDGIAQQHSMWQDIRYSQMEKGKAEACSQSEMNLSEVELGEIRGAARSSECPLACSSSLHCASGICSSNSKLLDSSEDVFETWGEACDLLMHKWGDGQEEQVTTRL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0030276 (clathrin binding), GO:0019899 (enzyme binding), GO:0008092 (cytoskeletal protein binding), GO:0042805 (actinin binding), GO:0051117 (ATPase binding), GO:0003779 (actin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0019222 (regulation of metabolic process), GO:0051240 (positive regulation of multicellular organismal process), GO:0051241 (negative regulation of multicellular organismal process), GO:0071840 (cellular component organization or biogenesis), GO:0051239 (regulation of multicellular organismal process), GO:0045927 (positive regulation of growth), GO:0050793 (regulation of developmental process), GO:0065008 (regulation of biological quality), GO:0048522 (positive regulation of cellular process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0051094 (positive regulation of developmental process), GO:0051093 (negative regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0040008 (regulation of growth), GO:0048639 (positive regulation of developmental growth), GO:0045597 (positive regulation of cell differentiation), GO:0050773 (regulation of dendrite development), GO:0051129 (negative regulation of cellular component organization), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0030154 (cell differentiation), GO:0051961 (negative regulation of nervous system development), GO:0048731 (system development), GO:0001558 (regulation of cell growth), GO:0060255 (regulation of macromolecule metabolic process), GO:0051130 (positive regulation of cellular component organization), GO:0030307 (positive regulation of cell growth), GO:2000026 (regulation of multicellular organismal development), GO:0042127 (regulation of cell population proliferation), GO:0007204 (positive regulation of cytosolic calcium ion concentration), GO:0031325 (positive regulation of cellular metabolic process), GO:0045596 (negative regulation of cell differentiation), GO:0042391 (regulation of membrane potential), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0045595 (regulation of cell differentiation), GO:0031323 (regulation of cellular metabolic process), GO:0016043 (cellular component organization), GO:0080090 (regulation of primary metabolic process), GO:0051128 (regulation of cellular component organization), GO:0051962 (positive regulation of nervous system development), GO:0090066 (regulation of anatomical structure size), GO:0048638 (regulation of developmental growth), GO:0008284 (positive regulation of cell population proliferation), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0045664 (regulation of neuron differentiation), GO:0032535 (regulation of cellular component size), GO:0010562 (positive regulation of phosphorus metabolic process), GO:0045773 (positive regulation of axon extension), GO:0045666 (positive regulation of neuron differentiation), GO:0031344 (regulation of cell projection organization), GO:0051246 (regulation of protein metabolic process), GO:0060284 (regulation of cell development), GO:0010720 (positive regulation of cell development), GO:0048814 (regulation of dendrite morphogenesis), GO:0050769 (positive regulation of neurogenesis), GO:0051960 (regulation of nervous system development), GO:0061387 (regulation of extent of cell growth), GO:0022008 (neurogenesis), GO:0050770 (regulation of axonogenesis), GO:0050768 (negative regulation of neurogenesis), GO:0007399 (nervous system development), GO:0031346 (positive regulation of cell projection organization), GO:0051247 (positive regulation of protein metabolic process), GO:0030516 (regulation of axon extension), GO:0031345 (negative regulation of cell projection organization), GO:0010721 (negative regulation of cell development), GO:0030182 (neuron differentiation), GO:0051174 (regulation of phosphorus metabolic process), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0031399 (regulation of protein modification process), GO:0050772 (positive regulation of axonogenesis), GO:0045937 (positive regulation of phosphate metabolic process), GO:0008361 (regulation of cell size), GO:0019220 (regulation of phosphate metabolic process), GO:0050774 (negative regulation of dendrite morphogenesis), GO:0050767 (regulation of neurogenesis), GO:0048699 (generation of neurons), GO:0031401 (positive regulation of protein modification process), GO:0042325 (regulation of phosphorylation), GO:0001932 (regulation of protein phosphorylation), GO:0042327 (positive regulation of phosphorylation), GO:0001934 (positive regulation of protein phosphorylation), GO:0010975 (regulation of neuron projection development), GO:0010799 (regulation of peptidyl-threonine phosphorylation), GO:0010800 (positive regulation of peptidyl-threonine phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0150034 (distal axon), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0044297 (cell body), GO:0030427 (site of polarized growth), GO:0036477 (somatodendritic compartment), GO:0005737 (cytoplasm), GO:0043025 (neuronal cell body), GO:0098857 (membrane microdomain), GO:0120025 (plasma membrane bounded cell projection), GO:0097447 (dendritic tree), GO:0030426 (growth cone), GO:0043005 (neuron projection), GO:0045121 (membrane raft), GO:0030425 (dendrite), GO:0030424 (axon)