Protein: DNA repair protein RAD50 (A0A1L8GVF0)
Organism: Xenopus laevis (African clawed frog)
Subcellular location: Chromosome, telomere
InterPro domains:
- IPR038729: Rad50/SbcC-type AAA domain (domain) [6-234]
- IPR004584: DNA repair protein Rad50, eukaryotes (family) [2-1311]
- IPR013134: RAD50, zinc hook (domain) [634-733]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [3-1310]
Sequence:
MSKIEKMSIQGVRSFGINDKNKQVIQFFTPLTILVGPNGAGKTTIIECLKYMTTGDFPSGSKGNTFVYHPKLAHETDVRAQICLQLKDVNGEPVAVQRSIICRQKGKSTECKTVDCVITRIKHGGPVSLRPKCEEMNKEMISALGVSSAVLNNVIFCHQEDSNWPLSEGKRLKGKFDEIFSITRYSKALETLRDVRMKEDQNVSNYQEEIKYLKENKEKAREIQDNLQSKEKQLTVSKENVKSIESQLEPLKDRLADIQRNLFKVIRLENEIKALESRKRTMEQDNQDLMEKMEKVFQGTDEELNEMYQNQCFVREKERKLNDHQREMDRACKESQRLNREKGELLVQQGHLQLEADNHQRYIKTRDSLIKSLAVQLELDGFELTPFNQRQTSNFQMLVKERQEEVEAHANQILREFSEREAMQQRQIDEIRDKKTGLERTIELKSSTESKKHTDLKKVKYDLQQLEGTSDRLHELDEELQKTAHALENVEKSCNLEALKGEVVQLQTQKSELDRNVRELDQEMEQLNKHTMTRTQMDMLKNDKADKDEQIRKMKSRHNDELISLYEYFPNKKQLEDWLYSKREDINQTRDKLARLTKELVAAEQNSNHLSNELCQKEKQSASFEEKVFDVCGSQDFNSDLSQLLEDIEKTSKQRAMLAGATAVYTQFITTLTEENQPCCPVCQRTFPSEAEVQDVINDMQSKLCLVPDKLKAAEDELKRKEKRKDEMMELKPMRQMLSDLKEKEIPEIRNKLEAINREIKRLQNDVEEQESLIVTFVSEEARAEACLQDISLMEQYQMELRDVDQKIAHYATKLLGVDLNRTVQQVNQEKLEKHHSLDNVSRRIELLQNHLQNQQEQVQQLKSRVNELTAEKLHISSNLQQRQQLEEQNVELTTELHCLSIEIKESREQVFPLESTLQKLQQEKQALLQRKESSYREAQEKVNDIKEKVKKINLHTKDIEKYIQDGKEEFKEQKESELQELTVRLNECEELKEKINREMVTIRQDIDTQKIQERCLQDNLTLRKRIEELKQVEEERDQLLKEMGQMKVTQMEKEYQELENKRETLKTNHSLTLGRQKGFEDEILRFKNELNEPKYKDAEEEYREKMIVMRTTELAIKDLDIYFKTMDQAIMKFHSIKMEEINKIIRDLWCSTYRGQDIEYIEIQSEPDEGISAADNRRTYNYRVVMIKGDTELDMRGHCSAGQKVLASLIIRLALAEIFCSNCGVLALDEPTTNLDHENIDSLAHALVEIIKSRSRQRNFQLIVITHNEDFVELLGRSEYVEHFYRIKKNIDQCSEIIRCSVSSLASYLH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0051716 (cellular response to stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0033554 (cellular response to stress), GO:0016043 (cellular component organization), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0006974 (cellular response to DNA damage stimulus), GO:0006259 (DNA metabolic process), GO:0006996 (organelle organization), GO:0000723 (telomere maintenance), GO:0006310 (DNA recombination), GO:0006281 (DNA repair), GO:0051276 (chromosome organization), GO:0032200 (telomere organization), GO:0006312 (mitotic recombination), GO:0016233 (telomere capping), GO:0006302 (double-strand break repair)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)