lokahq/bioreason-rl huggingface dataset:
Protein: Hyaluronidase (A6IE91)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR017853: Glycoside hydrolase superfamily (homologous_superfamily) [47-368]
- IPR018155: Hyaluronidase (family) [3-456]
- IPR013785: Aldolase-type TIM barrel (homologous_superfamily) [37-457]
Sequence:
MQLLSEGQLRRCVVQPVHLTSGLLIFFILKSISSLKPARLPVYQRKPFIAAWNAPTDLCLIKYNLAVNLKVFQMVGSPRLKDRRQNVVIFYANKLGSYPWYTSEGVPINGGLPQNTSLQVHLEKAYQDINYYIPSENFSGLAVIDWEYWRPQWARNWNTKDIYRQKSRTLISDMKENISTADIEYLAKATFEKSAKAFMEETIKLGIKSRPKGFWGYYLYPDCHNYNFYATNYTGSCPEEEVLRNNDLSWLWNSSTALYPAVSIRKSFADSENTLHFSQFRVRESLRISTMTSHDYALPVFVYTRLGYKEEPLLFLSKQDLISTIGESAALGAAGIVVWGDMNLTSSAENCTKVNRFVNSDFGSYVINVTTAAEVCSRHLCKNNGRCARKTWKAAHYLHLNPASYHIEASADREFVVKGRASDADLAAMAENFLCHCYEGYEGADCRDMTEASGPSGVSVSSSSVITLCLIALAGHQSIQL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds), GO:0015929 (hexosaminidase activity), GO:0004415 (hyalurononglucosaminidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901575 (organic substance catabolic process), GO:0043170 (macromolecule metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0009057 (macromolecule catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:1901136 (carbohydrate derivative catabolic process), GO:0006022 (aminoglycan metabolic process), GO:0006026 (aminoglycan catabolic process), GO:0030203 (glycosaminoglycan metabolic process), GO:0006027 (glycosaminoglycan catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0031090 (organelle membrane), GO:0098857 (membrane microdomain), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0045121 (membrane raft), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0000139 (Golgi membrane)
Protein: Vitronectin, isoform CRA_a (A6HH54)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR036024: Somatomedin B-like domain superfamily (homologous_superfamily) [4-35]
- IPR001212: Somatomedin B domain (domain) [1-31]
- IPR036375: Hemopexin-like domain superfamily (homologous_superfamily) [118-163]
- IPR018487: Hemopexin-like repeats (repeat) [124-169]
- IPR051298: Heme transport and cell adhesion protein (family) [78-169]
- IPR020436: Somatomedin B domain, chordata (domain) [4-27]
Sequence:
MASKKCQCDELCTYYQSCCVDYMEQCKPQVTRGDVFTMPEDEYWSYDYPEETKNSTSTGVQSENTSLHFNLKPRAEETIKPTTPDPQEQSNTQEPEVGQQGVAPRPDTTDEGTSEFPEEELCSGKPFDAFTDLKNGSLFAFRGEYCYELDETAVRPGLPSLASTVRGRPTCSRVVSTGALRMVSWTLIIPETSLKASVAYQTTLTQP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:1901681 (sulfur compound binding), GO:0097367 (carbohydrate derivative binding), GO:0008201 (heparin binding), GO:0005518 (collagen binding), GO:0005539 (glycosaminoglycan binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0048856 (anatomical structure development), GO:0048513 (animal organ development), GO:0048839 (inner ear development), GO:0007423 (sensory organ development), GO:0043583 (ear development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix)
Protein: Mitogen-activated protein kinase kinase kinase 14 (Predicted), isoform CRA_b (A6HJQ9)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [413-425]
- IPR000719: Protein kinase domain (domain) [302-557]
- IPR017441: Protein kinase, ATP binding site (binding_site) [308-332]
- IPR050538: Mitogen-activated protein kinase kinase kinase (family) [17-551]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [307-556]
- IPR042787: M3K14, catalytic domain (domain) [295-562]
Sequence:
MWLCPFLDSQSESLDQIPNNVAHATEGKMARVCRKGKRHSKARKKRRKRRSKSLAQAGVALAKPLPRTPEQESCTIPVQEDESPLGNLYARNVSQFTKPLKGPGLGHLCFKKQDEGLRPVLPRPELHKLISPLQCLNHVWKLHHPQATGPLPHPTHPFPFSRMPHPFPFYPLEPWRPYTLNPAFLDKLAAVSGQRPLPGPPHLSKPAYRDSQKPLPGPHLESSCLSREALEKVPAEEYLVHALQGSVSSGQAHSLASLAKTWSSGSSKLQRFSPETEDNEGVLLTEKLKPVDYEYREEVHWMTHQPRVGRGSFGEVHRMKDKQTGFQCAVKKVRLEVFRAEELIACAGLSSPRIVPLYGAVREGPWVNIFMELLEGGSLGQLIKQKGCLPEDRALYYLGQALEGLEYLHTHRVLHGDVKADNVLLSSDGSRAALCDFGHALCLQPDGLGKSLLTGDYIPGTETHMAPEVVLGKPCDAKVDIWSSCCMMLHMLNGCHPWTQYFRGPLCLKIASEPPPVREIPPSCTPLTAQAIQEGLRKEPIHRASAMELRRKVGKALQEVGGLKSPWKGEYKEPRPPPQDQAPCPQTLHTLPRENPPAKANTDGAPERQPPLPPEPPEPNKAPALNLSKEESGTWEPLPLSSLDPAPAKGPSLPDRRATFPELELQQLEIELFLNSLSQPFSLEEQEQILSCLSIDSLSLSEDSEKNPSKASQSSRDTLSSGVHSWSSQAEARSSSCSMALARGRPTDIPSYFNGVKVQIQSLNGEHLHIREFHRVKVGDIATGISSQIPATAFSLVTKDGQPVCYDMEVPDSGIDLQCTLAPDGSFAWAWRVKHGQLENRP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0006793 (phosphorus metabolic process), GO:0036211 (protein modification process), GO:0006796 (phosphate-containing compound metabolic process), GO:0043412 (macromolecule modification), GO:0006468 (protein phosphorylation), GO:0016310 (phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Nuclear mitotic apparatus protein 1, isoform CRA_d (A6I6Z5)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR051841: Microtubule and Golgi organization protein (family) [1-183]
Sequence:
MTRNRVCPPHLKTCYPLESRPALSLATITDEEMKTGDPRETLRRASMQPAQIAEGAGITTRQQRKRVSSETHQGPGTPESKKATSCFPRPMTPRDRHEGRKQNSTADAQKKAAPVLKQSDRRQSMAFSILNTPKKLGNSLLRRGTSKKTPAKVSPNPRSGTRRSPRIATTTAGAATAATTPRAKGKAKH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0015631 (tubulin binding), GO:0008017 (microtubule binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0022008 (neurogenesis), GO:0030182 (neuron differentiation), GO:0007399 (nervous system development), GO:0048699 (generation of neurons)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0042995 (cell projection), GO:0120025 (plasma membrane bounded cell projection), GO:0043005 (neuron projection), GO:0030424 (axon)
Protein: Beta-globin chain (Q63066)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR009050: Globin-like superfamily (homologous_superfamily) [2-134]
- IPR012292: Globin/Protoglobin (homologous_superfamily) [2-135]
- IPR050056: Hemoglobin and related oxygen transporters (family) [1-135]
- IPR000971: Globin (domain) [3-135]
- IPR002337: Hemoglobin, beta-type (family) [8-135]
Sequence:
MVHFTAEEKAAIISIWEKVDLEKIGGETLGRLLIVYPWTQRFFDKFGNLSSPLAIMGNPRIRAHGKKVLTSLGSAVENMDNLKETFAHLSELHCDKLHVDPQNFKLLGNMLVIVLSTHFAKEFTPEVQAAWQKLV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0046906 (tetrapyrrole binding), GO:0020037 (heme binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:0014070 (response to organic cyclic compound)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0005833 (hemoglobin complex)
Protein: Jumonji domain containing 2C (Predicted), isoform CRA_a (A6J816)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR003347: JmjC domain (domain) [144-310]
- IPR003349: JmjN domain (domain) [15-58]
Sequence:
MEVVEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNLLIPAPIQQMVTGQSGLFTQYNIQKKPMTVKEFRQLANSSKYCTPRYLDYEDLERKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKLCTCRNDMVKISMDIFVKKFQPDRYQIWKQGKDIYTIDHTKPTPESTPEVKTWLQRRKKLRKAPKSLQGNKSLSKRPKAEEDEEFAEFIGEEVSSPAVCPRHLKVTEKPEKFKLANIGASSEKEASDTRIQVDQSLTNDTKLSGKSCINSSVIDEIQPENDTANAVTSPSTLKKASDLIPFSHGHITGKESRLLKILQLESPKIPSSLAESNRVLTEGEENDEEGHASNLEPGEVPDALSEERNGLNVPKIIEGQPKTTKSWRHPLGKPPARSPMTLVKQQVASDEELPEVLSIDEEVEETESWAKPLIHLWQTKSPNFMAEQEYNATVAKMEPNCAICTLLMPYYKVVMVSLLMRSVMDGCVPDAKEMHGLQNAVSAI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0009636 (response to toxic substance)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000785 (chromatin), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome)
Protein: RCG21090 (F7FMI9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [660-732]
- IPR013087: Zinc finger C2H2-type (domain) [646-733]
- IPR039938: Transcription factor Sp4-like (family) [1-697]
Sequence:
MSDQKKEEEEEAAAAMATEGGKTSEPENNNKKPKTSGSQDSQPSPLALLAATCSKIGTPGENQATGQQQIIIDPSQGLVQLQNQPQQLELVTTQLAGNAWQLVASTPPASKENNVSQPASSSSSSSSSNNGSSSPTKTKSGNPSTPNQFQVIQVQNPSGSVQYQVIPQLQTVEGQQIQINPTSSSSLQDLQGQIQLISAGNNQAILTAANRTASGNILAQNLANQTVPVQIRPGVSIPLQLQTLPGTQAQVVTTLPINIGGVTLALPVINNVTAGGGTGQVGQPTTTTTDSGTSNGNQLVSTPTTSTAPASTMPESPSSSTTCTTTASTSLTSSDTLVSSADTGQYASTSASSSERTIEEPQTPAATESEAQSSSQLQSNGIQNAQDQSNSLQQVQIVGQPILQQIQIQQPQQQIIQAIPPQSFQLQSGQTIQTIQQQPLQNVQLQAVNPTQVLIRAPTLTPSGQISWQTVQVQNIQSLSNLQVQNAGLSQQLTITPVSSSGGTTLAQIAPVAVAGAPITLNTAQLASVPNLQTVSVANLGAAGVQVQGVPVTITSVAGQQQGQDGVKVQQATIAPVTVAVGGIANATIGAVSPDQLTQVHLQQGQQTSDAEVQPGKRLRRVACSCPNCREGEGRGSSEPGKKKQHVCHIEGCGKVYGKTSHLRAHLRWHTGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKRFECPECSKRFMRSDHLSKHVKTHQNKKGGGTALAIVTSGELDSSVTEVLGSPRIVTVAAISQDSNPATPNVSTNMEEF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0006357 (regulation of transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Delta-1-pyrroline-5-carboxylate synthase (A6JH60)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR036393: Acetylglutamate kinase-like superfamily (homologous_superfamily) [60-358]
- IPR005715: Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase (family) [71-360]
- IPR041744: Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain (domain) [63-354]
- IPR005766: Delta l-pyrroline-5-carboxylate synthetase (family) [16-792]
- IPR016163: Aldehyde dehydrogenase, C-terminal (homologous_superfamily) [581-729]
- IPR020593: Gamma-glutamyl phosphate reductase GPR, conserved site (conserved_site) [678-699]
- IPR016161: Aldehyde/histidinol dehydrogenase (homologous_superfamily) [363-770]
- IPR016162: Aldehyde dehydrogenase, N-terminal (homologous_superfamily) [373-769]
- IPR019797: Glutamate 5-kinase, conserved site (conserved_site) [301-318]
- IPR015590: Aldehyde dehydrogenase domain (domain) [363-625]
- IPR000965: GPR domain (domain) [362-771]
- IPR001048: Aspartate/glutamate/uridylate kinase (domain) [71-329]
- IPR001057: Glutamate/acetylglutamate kinase (family) [109-323]
Sequence:
MLRHVQRSGLQPFSQRLLPWVQSIALPRSHRVQPSAIRHVRSWSNIPFITVPLSRAHGKPFAHRSELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSVLQNQGREMMLVTSGAVAFGKQRLRHEILLSQSVRQALHSGQNHLKEMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIVNTNDAVVPPAEPNSDLQGVNVISVKDNDSLAARLAVEMKTDLLIVLSDVEGLFDSPPGSDDAKLIDIFYPGDQQSVTFGTKSRVGLGGMEAKVKAALWALQGGTSVVIANGTHPKVSGHVITDIVEGKKVGTFFSEVKPAGPTVEQQGEMARSGGRMLATLEPEQRAEIINHLADLLTDQREEILLANKKDLEEAEGRLAGPLLKRLSLSTSKLNSLAIGLRQIAASSQESVGRVLRRTRIAKNLELEQVTVPIGVLLVIFESRPDCLPQVAALAIASGNGLLLKGGKEAMHSNRILHLLTQEALSIHGVKEAIQLVNTREEVEDLCRLDKIIDLIIPRGSSQLVRDIQKAAKGIPVMGHSEGICHMYVDSEASVDKVTRLVRDSKCEYPAACNALETLLIHRDLLRTPLFDQIIDMLRVEQVKIHAGPKFASYLTFSPSEVKSLRTEYGDLEVCIEVVDSVQEAIDHIHKYGSSHTDVIVTENEKTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGLEGLLTTKWLLRGQDHVVSDFSEHGRLKYLHENLPVPQRHFS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016301 (kinase activity), GO:0016774 (phosphotransferase activity, carboxyl group as acceptor), GO:0019202 (amino acid kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0009266 (response to temperature stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005740 (mitochondrial envelope), GO:0043231 (intracellular membrane-bounded organelle), GO:0031966 (mitochondrial membrane)
Protein: Prospero-related homeobox 1 (Predicted) (A6JGW7)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR039350: Prospero homeodomain family (family) [63-575]
Sequence:
MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQHADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTGSEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDVDRLCDEHLRAKRARVENIIRGMSHSPSVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLKQQLEDMQKQLRQLQEKFYQVYDSTDSENDEDGDLSEDSMRSEILDARAQDSVGRSDNEMCELDPGQFIDRARALIREQEMAENKPKREGSNKERDHGPNSLQPEGKHLAETLKQELNTAMSQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNPLDTFGNVQMPSSTDQTEALPLVVRKNSSEQSASGPATGGHHQPLHQSPLSATAGFTTPSFRHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSPAHPPSTAEGLSLSLIKSECGDLQDMSDISPYSGSAMKGYHPIT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0042826 (histone deacetylase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009991 (response to extracellular stimulus), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048732 (gland development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development), GO:0031667 (response to nutrient levels), GO:0061008 (hepaticobiliary system development), GO:0001889 (liver development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Propionate--CoA ligase (A6KI41)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR025110: AMP-binding enzyme, C-terminal domain (domain) [583-661]
- IPR020845: AMP-binding, conserved site (conserved_site) [313-324]
- IPR042099: ANL, N-terminal domain (homologous_superfamily) [30-569]
- IPR000873: AMP-dependent synthetase/ligase domain (domain) [115-528]
- IPR045851: AMP-binding enzyme, C-terminal domain superfamily (homologous_superfamily) [570-699]
- IPR032387: Acetyl-coenzyme A synthetase, N-terminal domain (domain) [47-107]
Sequence:
MGLPEERRKSGSGSRAREETGAEGRVRGWSPPPEVRRSAHVPSLQRYRELHRRSVEEPREFWGNIAKEFYWKTPCPGPFLQYNFDVTKGKIFTEWMKGATTNICYNVLDRNVHEKKLGDKVAFYWEGNEPGETTKITYRELLVQVCQFSNVLRKQGVQKGDRVAIYMPMILELVVAMLACARLGALHSIVFAGFSAESLCERILDSSCCLLITTDAFYRGEKLVNLKELADESLEKCREKGFPVRCCIVVKHLGRAELGMNDSPSQSPPVKRPCPDVQISWNEGVDLWWHELMQQAGDEFEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHPEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDEGRLWSIVDKYKVTKFYTAPTAIRMLMKFGDDPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGSQRCPIVDTFWQTETGGHMLTPLPGATPMKPGSASFPFFGVAPAILNESGEELEGEAEGYLVFKQPWPGIMRTVYGNHTRFETTYFKKFPGYYVTGDGCRRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPTLTEELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLRKIAQNDHDLGDTSTVADPSVINHLFSHRCLTTQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016874 (ligase activity), GO:0016877 (ligase activity, forming carbon-sulfur bonds), GO:0016878 (acid-thiol ligase activity), GO:0016405 (CoA-ligase activity), GO:0003987 (acetate-CoA ligase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0006083 (acetate metabolic process), GO:0006082 (organic acid metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0019541 (propionate metabolic process), GO:0006631 (fatty acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0016053 (organic acid biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0006633 (fatty acid biosynthetic process), GO:0046394 (carboxylic acid biosynthetic process), GO:0046459 (short-chain fatty acid metabolic process), GO:0072330 (monocarboxylic acid biosynthetic process), GO:0032787 (monocarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Similar to postmeiotic segregation increased 1, isoform CRA_a (A6INU7)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR020568: Ribosomal protein uS5 domain 2-type superfamily (homologous_superfamily) [107-248]
- IPR036890: Histidine kinase/HSP90-like ATPase superfamily (homologous_superfamily) [1-191]
- IPR038973: DNA mismatch repair protein MutL/Mlh/Pms-like (family) [1-105]
- IPR036910: High mobility group box domain superfamily (homologous_superfamily) [460-553]
- IPR009071: High mobility group box domain (domain) [470-540]
- IPR013507: DNA mismatch repair protein, S5 domain 2-like (domain) [121-249]
- IPR014762: DNA mismatch repair, conserved site (conserved_site) [91-97]
Sequence:
MKQLPAATVRLLSSSQTITSVVSVVKELIENSLDAGANSIDVKLENYGFDKIEIRDNGAGIKAVDVPVMAVKYYTSKISSHEDLQTLTTYGFRGEALGAICNVAEAVIWQKSRVPDHRMALMSVLGTAVMGNMESVERYCEDSQIHLRGLFPKHDADHNSTSLSTPERSFIFINSRPVHQKDILKLIRHYYNLKCLKESTRLYPIFFLKIDVPSAEVDINLTPDKSQVLLQNKESVLIALENLLMTCYGPLPTTESYENNRVDVSSANVVISETTETDVLFNKMESSGNKYPNADTLAIPFQNDESRKNTDHHLNEQINIGHCDGHFSGEYSHINKDTFQNIPRNNLSSEANQSKHSETHSAGSIEHIQGENGRSGTGENGEDGKKTLPEKALEICADDWSKGNVFNSMGENIEPVKILVPQKSLSCKVTNSHPNPEPENLSVGPGSRTSNVIDNRPGQLTAYDLISSRAVKKPMSACALFIQDHRTQFLAENPKTGLEDVTAQIKAQWETLSEEEKHKYEEKAKKDLERYNNQMKKAIEQEAQVSLKDGRKKLRATGAWGCTQRHKVKDLSNQPKLDELFQSQNEKKSENIKITKIPFSMENLKVNFNKQKEVDLEEKDEICLIHSLKFPDAWLVTSRADVMLLNPYRVEEALLFKRLLENHKFLAEPLEKPIVLTESLFNGSDYLEVLHKMSTVEERCRGSVYLCDPRLTANGFKIRLTPGVSSAENYLEIEGMAKCLPFYGVMDLKEILNAIVNKNAKEIYECRPRKVINYLEGEAVRLSRQLPMYLPQEDVQDLIYKMKHQFGKEIKGCVHGRPFLHHLIHLPGTS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003690 (double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0009410 (response to xenobiotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)