Protein: DCC-interacting protein 13-alpha isoform X1 (A0A8M9PV15)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell projection, ruffle. Cytoplasmic vesicle, phagosome. Early endosome membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Membrane; Peripheral membrane protein. Nucleus
InterPro domains:
- IPR047236: DCC-interacting protein 13-alpha/beta, PH domain (domain) [252-376]
- IPR004148: BAR domain (domain) [7-247]
- IPR001849: Pleckstrin homology domain (domain) [277-377]
- IPR027267: AH/BAR domain superfamily (homologous_superfamily) [2-302]
- IPR037929: DCC-interacting protein 13-alpha, BAR domain (domain) [20-234]
- IPR006020: PTB/PI domain (domain) [495-639]
- IPR047237: DCC-interacting protein 13-alpha/beta, PTB domain (domain) [488-623]
- IPR047181: DCC-interacting protein 13-alpha/beta (family) [2-707]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [265-642]
Sequence:
MPGIDKLPIEETLEDSPQTRSLLGVFEEDAAAISSYFNQLFKAMQRIYDAQNELSAATHLTSKLLKDYEKQRFPLGGDDEVMSSTLQQFAKVIDELSSCHAVLSTQLADAMMFPITQFQERDLREILILKEVFQLASDDHDAAVHRYSRLSKRKENEKVKNEVMEDVYTSRKKQHETTMHYFASLNMLQYKKKIALLEPLLGYMQAQISFFKLGSENLTQQWEDFLTNIGTSVQNVRREMDSDAEAMEQTIQDLKEASDPLYMPDPDPNRIPVNRNLTRKAGYLNTRNKTGLVSSSWERQYFFTQGGNLMSQSRGAVAGGLVMDIDNCSVMAVDCEDRRFCFQITAFDGKKAAVLQADSRKDCEEWIATINNISKRIYLSENPEEIAARVNQSALEAVTPSPSFQQRHESFRPNTQGKVKASRSGSQCSVGSESPALSSLSLDSLVAPDTPIQFDIISPVSEEHTSQTKSSAQGRRTNPFGESGGSQSEESEDSILHQLFIVRFLGSMEVKATESSDVIYETMRQILAARAIHNIFRMTESHLLVTCECLKLIDPQTQVTRLRFPLSSVVLCASHQENKRLFGFVLQTAGGRADGQPVTVCYIFESNNDGEKICDSIGLAKQIALHSEMDRKASQKQRELDKAKEKQQEELHKQKQIEKDLEEQSRLIAASSRPNQPAADGQFLVLSNSQSEDSDVGEEGLKKGESEA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048519 (negative regulation of biological process), GO:0023057 (negative regulation of signaling), GO:0051051 (negative regulation of transport), GO:0019222 (regulation of metabolic process), GO:0032879 (regulation of localization), GO:0051050 (positive regulation of transport), GO:0002683 (negative regulation of immune system process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0009893 (positive regulation of metabolic process), GO:0023051 (regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0048522 (positive regulation of cellular process), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0051049 (regulation of transport), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0080134 (regulation of response to stress), GO:0009966 (regulation of signal transduction), GO:0034762 (regulation of transmembrane transport), GO:0060255 (regulation of macromolecule metabolic process), GO:0032101 (regulation of response to external stimulus), GO:0060627 (regulation of vesicle-mediated transport), GO:0051130 (positive regulation of cellular component organization), GO:0044089 (positive regulation of cellular component biogenesis), GO:0044087 (regulation of cellular component biogenesis), GO:0009894 (regulation of catabolic process), GO:0002831 (regulation of response to biotic stimulus), GO:0051049 (regulation of transport), GO:0010646 (regulation of cell communication), GO:0031325 (positive regulation of cellular metabolic process), GO:0002697 (regulation of immune effector process), GO:0002698 (negative regulation of immune effector process), GO:0031323 (regulation of cellular metabolic process), GO:0045807 (positive regulation of endocytosis), GO:0051128 (regulation of cellular component organization), GO:0009896 (positive regulation of catabolic process), GO:0030100 (regulation of endocytosis), GO:0031347 (regulation of defense response), GO:0030100 (regulation of endocytosis), GO:0045088 (regulation of innate immune response), GO:0042176 (regulation of protein catabolic process), GO:1905153 (regulation of membrane invagination), GO:0031330 (negative regulation of cellular catabolic process), GO:0017157 (regulation of exocytosis), GO:0062207 (regulation of pattern recognition receptor signaling pathway), GO:0048260 (positive regulation of receptor-mediated endocytosis), GO:1900424 (regulation of defense response to bacterium), GO:0010468 (regulation of gene expression), GO:0050764 (regulation of phagocytosis), GO:0060972 (left/right pattern formation), GO:0010508 (positive regulation of autophagy), GO:1902117 (positive regulation of organelle assembly), GO:0033043 (regulation of organelle organization), GO:0031331 (positive regulation of cellular catabolic process), GO:0031329 (regulation of cellular catabolic process), GO:0010638 (positive regulation of organelle organization), GO:0010629 (negative regulation of gene expression), GO:0048259 (regulation of receptor-mediated endocytosis), GO:0007368 (determination of left/right symmetry), GO:0016241 (regulation of macroautophagy), GO:0044090 (positive regulation of vacuole organization), GO:0044088 (regulation of vacuole organization), GO:2000785 (regulation of autophagosome assembly), GO:1900242 (regulation of synaptic vesicle endocytosis), GO:0060099 (regulation of phagocytosis, engulfment), GO:0016239 (positive regulation of macroautophagy), GO:2000369 (regulation of clathrin-dependent endocytosis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0005769 (early endosome), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)