Protein: Huntingtin interacting protein 1, isoform CRA_a (A6J0C8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane
InterPro domains:
- IPR011417: AP180 N-terminal homology (ANTH) domain (domain) [39-304]
- IPR002558: I/LWEQ domain (domain) [764-1005]
- IPR013809: ENTH domain (domain) [32-160]
- IPR008942: ENTH/VHS (homologous_superfamily) [17-156]
- IPR032422: Huntingtin-interacting protein 1, clathrin-binding domain (domain) [482-572]
- IPR030224: Sla2 family (family) [29-1013]
- IPR035964: I/LWEQ domain superfamily (homologous_superfamily) [767-958]
Sequence:
MDRMASSMKQVPNPLPKVLSRRGVGAGMEAAERESFERTQTVSVNKAINTQEVAVKEKHARTCILGTHHEKGAQTFWSVVNRLPLSSNAMLCWKFCHVFHKLLRDGHPNVLKDSLRYKNELSDMSRMWGHLSEGYGQLCSIYLKLLRTRMEYHTKNPRFPGNLQMSDRQLDEAGESDVNNFFQLTVEMFDYLECELNLFQTVFNSLDMSRSVSVTTAGQCRLAPLIQVILDCSHLYDYTVKLLFKLHSCLPADTLQGHRDRFMEQFTKLKDLFQRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHISPVVVIPAEVSSPDSEPVLEKDDLMDMDASQQSLFDNKFDDIFGSSLSSDPFNFNNQNGVNKDEKDHLIERLYREISGLTGQLDNVKIESQRAMLQLKGRVSELEAELAEQQHLGRQATDDCEFLRTELDELKRQREDTEKAQRSLTEIEKKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQVSVARQAQVDLEREKKELADSFARTQEQQDVLETLKHELATSRQELQVLHGNLETSAQSEAKWLTQIAELEKEQGSLATAAAQREEEFSALRDQLESTQLKLAGAQDSMCQQIKDQRRILLAGARKAAELEIQEALGQLEEPALLISCAGATDHLLSKVNSVSSCLEQLEKSRSQYLACPEEISELLHSITLLGHLTSDTIIQGTATSLRAPPESADSLTEACRQYGRETLAYLSSLEEEGAMEKADTTAIANCLGKIKTIGEELLPRGLDIKQEELGDLVDKEMAATSAAIEAATTRIEEILSKSRAGDTGVKLEVNERILGSCTSLMQAIKVLVVASKDLQKEIVESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATIMVDAADLVVQGKGKFEELMVCSHEIAASTAQLVAASKVKANKGSLNLTQLQQASRGVNQATAAVVASTISGKSQIEETDSMDFSSMTLTQIKRQEMDSQVRVLELENDLQKERQKLGELRKKHYELAGVAEGWEEGTEASPSAVQEAVPDKE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0030276 (clathrin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006810 (transport), GO:0044085 (cellular component biogenesis), GO:0016192 (vesicle-mediated transport), GO:0043933 (protein-containing complex organization), GO:0022607 (cellular component assembly), GO:0006897 (endocytosis), GO:0065003 (protein-containing complex assembly), GO:0048268 (clathrin coat assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098552 (side of membrane), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0098793 (presynapse), GO:0071944 (cell periphery), GO:0030054 (cell junction), GO:0098794 (postsynapse), GO:0019898 (extrinsic component of membrane), GO:0005737 (cytoplasm), GO:0019897 (extrinsic component of plasma membrane), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0098562 (cytoplasmic side of membrane), GO:0045211 (postsynaptic membrane), GO:0042734 (presynaptic membrane), GO:0098590 (plasma membrane region), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0097060 (synaptic membrane), GO:0098890 (extrinsic component of postsynaptic membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0098888 (extrinsic component of presynaptic membrane), GO:0031234 (extrinsic component of cytoplasmic side of plasma membrane), GO:0098978 (glutamatergic synapse), GO:0009898 (cytoplasmic side of plasma membrane), GO:0030135 (coated vesicle), GO:0099243 (extrinsic component of synaptic membrane), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle), GO:0030136 (clathrin-coated vesicle)