Protein: DExD/H-box helicase 60 (A0A7P0T8Y0)
Organism: Homo sapiens (Human)
InterPro domains:
- IPR059032: DDX60-like, winged helix domain (domain) [1358-1440]
- IPR001650: Helicase, C-terminal domain-like (domain) [1226-1370]
- IPR055124: ATP-dependent RNA helicase DDX60, PIN-like domain (domain) [7-228]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [741-1358]
- IPR011545: DEAD/DEAH-box helicase domain (domain) [768-924]
- IPR052431: SKI2 subfamily ATP-dependent RNA helicases (family) [7-1680]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [760-956]
Sequence:
MERNVLTTFSQEMSQLILNEMPKAEYSSLFNDFVESEFFLIDGDSLLITCICEISFKPGQNLHFFYLVERYLVDLISKGGQFTIVFFKDAEYAYFNFPELLSLRTALILHLQKNTTIDVRTTFSRCLSKEWGSFLEESYPYFLIVADEGLNDLQTQLFNFLIIHSWARKVNVVLSSGQESDVLCLYAYLLPSMYRHQIFSWKNKQNIKDAYTTLLNQLERFKLSALAPLFGSLKWNNITEEAHKTVSLLTQVWPEGSDIRRVFCVTSCSLSLRMYHRFLGNREPSSGQETEIQQVNSNCLTLQEMEDLCKLHCLTVVFLLHLPLSQRACARVITSHWAEDMKPLLQMKKWCEYFILRNIHTFEFWNLNLIHLSDLNDELLLKNIAFYYENENVKGLHLNLGDTIMKDYEYLWNTVSKLVRDFEVGQPFPLRTTKVCFLEKKPSPIKDSSNEMVPNLGFIPTSSFVVDKFAGDILKDLPFLKSDDPIVTSLVKQKEFDELVHWHSHKPLSDDYDRSRCQFDEKSRDPRVLRSVQKYHVFQRFYGNSLETVSSKIIVTQTIKSKKDFSGPKSKKAHETKAEIIARENKKRLFAREEQKEEQKWNALSFSIEEQLKENLHSGIKSLEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEGKTTKDLSIAVQVMKRIHSLMEKYSELLQEDDRQLIARCLKYLGFDELASSLHPAQDAENDVKVKKRNKYSVGIGPARFQLQYMGHYLIRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMEKVLKESDDGVVVYVAPTKALVNQVAATVQNRFTKNLPSGEVLCGVFTREYRHDALNCQVLITVPACFEILLLAPHRQNWVKKIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKWYWKQEDKIIENNTASKRHVGRQAGFPKDYLQVKQSYKVRLVLYGERYNDLEKHVCSIKHGDIHFDHFHPCAALTTDHIERYGFPPDLTLSPRESIQLYDAMFQIWKSWPRAQELCPENFIHFNNKLVIKKMDARKYEESLKAELTSWIKNGNVEQARMVLQNLSPEADLSPENMITMFPLLVEKLRKMEKLPALFFLFKLGAVENAAESVSTFLKKKQETKRPPKADKEAHVMANKLRKVKKSIEKQKIIDEKSQKKTRNVDQSLIHEAEHDNLVKCLEKNLEIPQDCTYADQKAVDTETLQKVFGRVKFERKGEELKALAERGIGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFAQNSVYLDALNYRQMSGRAGRRGQDLMGDVYFFDIPFPKIGKLIKSNVPELRGHFPLSITLVLRLMLLASKGDDPEDAKAKVLSVLKHSLLSFKQPRVMDMLKLYFLFSLQFLVKEGYLDQEGNPMGFAGLVSHLHYHEPSNLVFVSFLVNGLFHDLCQPTRKGSKHFSQDVMEKLVLVLAHLFGRRYFPPKFQDAHFEFYQSKVFLDDLPEDFSDALDEYNMKIMEDFTTFLRIVSKLADMNQEYQLPLSKIKFTGKECEDSQLVSHLMSCKEGRVAISPFVCLSGNFDDDLLRLETPNHVTLGTIGVNRSQAPVLLSQKFDNRGRKMSLNAYALDFYKHGSLIGLVQDNRMNEGDAYYLLKDFALTIKSIRDL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003723 (RNA binding), GO:0003690 (double-stranded DNA binding), GO:0003725 (double-stranded RNA binding), GO:0003727 (single-stranded RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0023056 (positive regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0009607 (response to biotic stimulus), GO:0002684 (positive regulation of immune system process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0002682 (regulation of immune system process), GO:0023051 (regulation of signaling), GO:0051707 (response to other organism), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0002831 (regulation of response to biotic stimulus), GO:0032103 (positive regulation of response to external stimulus), GO:0050776 (regulation of immune response), GO:0043207 (response to external biotic stimulus), GO:0010646 (regulation of cell communication), GO:0002697 (regulation of immune effector process), GO:0002833 (positive regulation of response to biotic stimulus), GO:0080134 (regulation of response to stress), GO:0009966 (regulation of signal transduction), GO:0050778 (positive regulation of immune response), GO:0010647 (positive regulation of cell communication), GO:0032101 (regulation of response to external stimulus), GO:0031349 (positive regulation of defense response), GO:0002699 (positive regulation of immune effector process), GO:0009615 (response to virus), GO:0031347 (regulation of defense response), GO:0045089 (positive regulation of innate immune response), GO:0045088 (regulation of innate immune response), GO:0062207 (regulation of pattern recognition receptor signaling pathway), GO:0062208 (positive regulation of pattern recognition receptor signaling pathway), GO:0039531 (regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway), GO:0039535 (regulation of RIG-I signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0045111 (intermediate filament cytoskeleton)