Protein: TNF receptor-associated factor (A0A9K3Y7P7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm
InterPro domains:
- IPR049441: TRAF2, second zinc finger (domain) [104-122]
- IPR049342: TRAF1-6, MATH domain (domain) [371-489]
- IPR037305: TNF receptor-associated factor 2, MATH domain (domain) [330-493]
- IPR002083: MATH/TRAF domain (domain) [347-492]
- IPR017907: Zinc finger, RING-type, conserved site (conserved_site) [49-58]
- IPR012227: TNF receptor-associated factor TRAF, metazoa (family) [5-495]
- IPR027133: TNF receptor-associated factor 2, C3HC3D-type RING zinc finger (domain) [31-73]
- IPR001293: Zinc finger, TRAF-type (domain) [125-234]
- IPR018957: Zinc finger, C3HC4 RING-type (domain) [34-72]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [1-240]
- IPR032070: TNF receptor-associated factor, BIRC3 binding domain (domain) [263-326]
- IPR008974: TRAF-like (homologous_superfamily) [328-497]
- IPR001841: Zinc finger, RING-type (domain) [34-72]
Sequence:
MAAASVTSPGSLELLQPGFSKTLLGTRLEAKYLCSACRNILRRPFQAQCGHRYCSFCLTSILSSGPQNCAACVHEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKKHHTEQECPKRSLSCQHCRAPCSHADLELHYEVCPKFPLTCDGCGKKISQEKLQDHVRTCSKCRVLCRFHAIGCSELVETEDLQDHELQRLREHLALLLSSFLESQASQNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFARKRQEAIAGRTPAIFSPAFFTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNNREHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKIEAKNSYVRDDAIFIKAIVDLTGL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0019900 (kinase binding), GO:0019901 (protein kinase binding), GO:0031435 (mitogen-activated protein kinase kinase kinase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0048519 (negative regulation of biological process), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0065009 (regulation of molecular function), GO:0048523 (negative regulation of cellular process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0044093 (positive regulation of molecular function), GO:0060548 (negative regulation of cell death), GO:0010941 (regulation of cell death), GO:0070887 (cellular response to chemical stimulus), GO:0051090 (regulation of DNA-binding transcription factor activity), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0007166 (cell surface receptor signaling pathway), GO:0080090 (regulation of primary metabolic process), GO:0010033 (response to organic substance), GO:0034097 (response to cytokine), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0043069 (negative regulation of programmed cell death), GO:0071310 (cellular response to organic substance), GO:0043067 (regulation of programmed cell death), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0019221 (cytokine-mediated signaling pathway), GO:0010468 (regulation of gene expression), GO:0051091 (positive regulation of DNA-binding transcription factor activity), GO:0042981 (regulation of apoptotic process), GO:0034612 (response to tumor necrosis factor), GO:0043066 (negative regulation of apoptotic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0051092 (positive regulation of NF-kappaB transcription factor activity), GO:0033209 (tumor necrosis factor-mediated signaling pathway), GO:0071345 (cellular response to cytokine stimulus), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0071356 (cellular response to tumor necrosis factor)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005938 (cell cortex), GO:0098857 (membrane microdomain), GO:0045121 (membrane raft)