lokahq/bioreason-rl huggingface dataset:
Protein: Claudin (F7FBN1)
Organism: Rattus norvegicus (Rat)
Function: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity
Subcellular location: Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein
InterPro domains:
- IPR006187: Claudin (family) [4-194]
- IPR004031: PMP-22/EMP/MP20/Claudin (family) [4-180]
- IPR017974: Claudin, conserved site (conserved_site) [49-64]
- IPR003550: Claudin-4 (family) [92-209]
Sequence:
MASMGLQVLGISLAVLGWLGVILSCSLPMWRVTAFIGSNIVTAQTSWEGLWMNCVVQSTGQMQCKMYDSMLALPQDLQAARALMVISIIVGALGMLLSVVGGKCTNCMEDETVKAKVMITAGAVFIVASMLIMVPVSWTAHNVIRDFYNPLVASGQKREMGASLYIGWAASGLLLLGGGLLCCNCPPRRNEKPYSAKYSAARSVPASNYV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0005515 (protein binding), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0008509 (monoatomic anion transmembrane transporter activity), GO:0015108 (chloride transmembrane transporter activity), GO:0015103 (inorganic anion transmembrane transporter activity), GO:0015267 (channel activity), GO:0005253 (monoatomic anion channel activity), GO:0005254 (chloride channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0048511 (rhythmic process), GO:0050896 (response to stimulus), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0007623 (circadian rhythm), GO:0044706 (multi-multicellular organism process), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0044703 (multi-organism reproductive process), GO:1901700 (response to oxygen-containing compound), GO:0007565 (female pregnancy), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0048545 (response to steroid hormone), GO:0014070 (response to organic cyclic compound), GO:1901654 (response to ketone), GO:0033993 (response to lipid), GO:0032570 (response to progesterone)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0045178 (basal part of cell), GO:0045177 (apical part of cell), GO:0071944 (cell periphery), GO:0016328 (lateral plasma membrane), GO:0016020 (membrane), GO:0009925 (basal plasma membrane), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0016324 (apical plasma membrane), GO:0016327 (apicolateral plasma membrane)
Protein: SLIT and NTRK-like family, member 1 (Predicted) (A6HUD1)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR000483: Cysteine-rich flanking region, C-terminal (domain) [212-579]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [20-580]
- IPR003591: Leucine-rich repeat, typical subtype (repeat) [81-517]
- IPR001611: Leucine-rich repeat (repeat) [139-483]
Sequence:
MLLWILLLETSLCFAAGNVTGDVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLCPLKNRVDSSLPAPPAQEETFAPGPLPTPFKINGQDEHATPGAVPNGGTKIPGNWQLKIKPTPPIATGSARNKPPVHGLPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRRSHFVDYKNLILLDLGNNNIANIENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEVLMSDLKCETPVNFFRKDFMLLSNDEICPQLYAKISPTLTSHSKNSTGLAETGTHSNSYLDTSRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINSLQTVCDSSYWHNGPYNADGAHRVYDCGSHSLSD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0065008 (regulation of biological quality), GO:0050794 (regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0050803 (regulation of synapse structure or activity), GO:0050807 (regulation of synapse organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0098794 (postsynapse), GO:0071944 (cell periphery), GO:0045211 (postsynaptic membrane), GO:0098590 (plasma membrane region), GO:0045202 (synapse), GO:0005886 (plasma membrane), GO:0099572 (postsynaptic specialization), GO:0097060 (synaptic membrane), GO:0099634 (postsynaptic specialization membrane), GO:0098984 (neuron to neuron synapse), GO:0098982 (GABA-ergic synapse), GO:0014069 (postsynaptic density), GO:0098978 (glutamatergic synapse), GO:0032279 (asymmetric synapse), GO:0098839 (postsynaptic density membrane)
Protein: Cytochrome P450 26A1 (A6I173)
Organism: Rattus norvegicus (Rat)
Subcellular location: Microsome membrane; Peripheral membrane protein
InterPro domains:
- IPR017972: Cytochrome P450, conserved site (conserved_site) [435-444]
- IPR001128: Cytochrome P450 (family) [45-472]
- IPR002403: Cytochrome P450, E-class, group IV (family) [66-460]
- IPR036396: Cytochrome P450 superfamily (homologous_superfamily) [33-493]
Sequence:
MGLPALLASALCTFVLPLLLFLAALKLWDLYCVSSRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGAGCLSNLHDSSHKQRKKVIMQAFNREALQCYVPVIAEEVSGCLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPGPAGGGEDEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGVKARNLIHARIEENIRAKIRRLQAAEPDAGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREEIKSKGLLCKSHHEDKLDMETLEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVADSFTNKEEFNPDRFTSLHPEDTSRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARRCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFQGDI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen), GO:0004497 (monooxygenase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0042221 (response to chemical), GO:0009991 (response to extracellular stimulus), GO:1901700 (response to oxygen-containing compound), GO:0007584 (response to nutrient), GO:0010033 (response to organic substance), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0072001 (renal system development), GO:0033273 (response to vitamin), GO:0001822 (kidney development), GO:0033993 (response to lipid), GO:0031667 (response to nutrient levels), GO:0032526 (response to retinoic acid), GO:0033189 (response to vitamin A)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Peroxisomal membrane protein PEX16 (A6HNG5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Peroxisome membrane
InterPro domains:
- IPR013919: Peroxisome membrane protein, Pex16 (family) [9-336]
Sequence:
MEKLRLLGLRYQEYVTRHPAATAQLETAVRGLSYLLAGRFSDSHELSELVYSASNLLVLLNDGILRKELRKKLPVSLSQQKLLTWLSVLECVEVFMEMGAAKVWGEVGRWLVIALIQLAKAVLRMFLLIWFKTGIQTSPPIVPLDRETQAQPLDGDHNLGSPEPSYVGKRSNRVVRTLQNSPSLHSRHWGAPQQREIRQKQQQEELSTPPTPLGLQETIAESLYIARPLLHLLSLGLWGQRSWAPWLLSGVVDMTSLSLLSDRKNLTRRERLELRRRTILLLYYLLRSPFYDRFSEAKILFLLQLLADHIPGIGLVARPLMDYLPSWQKIYFYSWG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0007031 (peroxisome organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0031090 (organelle membrane), GO:0042579 (microbody), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0031903 (microbody membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0005777 (peroxisome), GO:0005778 (peroxisomal membrane)
Protein: Procollagen, type IV, alpha 1, isoform CRA_a (A6IWQ3)
Organism: Rattus norvegicus (Rat)
Function: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen
Subcellular location: Membrane. Secreted, extracellular space, extracellular matrix, basement membrane
InterPro domains:
- IPR001442: Collagen IV, non-collagenous (domain) [874-1098]
- IPR016187: C-type lectin fold (homologous_superfamily) [873-1097]
- IPR036954: Collagen IV, non-collagenous domain superfamily (homologous_superfamily) [870-1098]
- IPR008160: Collagen triple helix repeat (repeat) [5-869]
- IPR050938: Collagen and Collagen-like Structural Proteins (family) [311-701]
Sequence:
MRLKGDKGDPGFPGQPGMPGRAGTPGRDGHPGLPGPKGSPGSIGLKGERGPPGGVGFPGSRGDIGPPGPPGVGPIGPIGEKGQAGLPGGPGSPGLPGPKGEAGKVVPLPGPPGAAGLPGSPGFPGPQGVDGLPGEIGRPGSPGRPGFNGLPGNPGPQGQKGEPGIGLPGLKGQPGLPGIPGTPGEKGSIGGPGVPGEQGLTGPPGLQGIRGDPGPPGVQGPAGPPGVPGIGPPGAMGPPGGQGPPGSSGPPGVKGEKGFPGFPGLDMPGPKGDKGSQGLPGLTGQSGLPGLPGQQGTPGVPGFPGSKGEMGVMGTPGQPGSPGPAGAPGLPGEKGDHGFPGSSGPRGDPGFKGDKGDVGLPGMPGSMEHVDMGSMKGQKGDQGEKGQIGPTGDKGSRGDPGTPGVPGKDGQAGHPGQPGPKGDPGLSGIPGSPGLPGPKGSVGGMGLPGSPGEKGVPGIPGSQGVPGSPGEKGAKGEKGQSGLPGIGIPGRPGDKGDQGLAGFPGSPGEKGEKGSAGTPGMPGSPGPRGSPGNIGHPGSPGLPGEKGDKGLPGLDGVPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEQGLPGRGFPGFPGTKGDKGSKGEVGFPGLAGSPGIPGAKGEQGFMGPPGPQGQPGLPGTPGHPVEGPKGDRGPQGQPGLPGHPGPMGPPGFPGIDGPKGDKGNPGWPGAPGAPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGQKGLPGLQGVKGDQGDQGIPGPKGLQGPPGPPGPYDVIKGEPGLPGPEGPPGLKGLQGPPGPKGQQGVTGSVGLPGPPGVPGFDGAPGQKGETGPFGPPGPRGFPGPPGPDGLPGSMGPPGTPSVDHGFLVTRHSQTTDDPLCPPGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTMPFLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPISGDNIRPFISRCAVCEAPAMVMAVHSQTIQIPQCPNGWSSLWIGYSFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANAYSFWLATIERSEMFKKPTPSTLKAGELRTHVSRCQVCMRRT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0005201 (extracellular matrix structural constituent)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0009888 (tissue development), GO:0030154 (cell differentiation), GO:0060429 (epithelium development), GO:0030855 (epithelial cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Protein tyrosine phosphatase, receptor-type, F interacting protein, binding protein 2, isoform CRA_b (A6I7S5)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR037619: Liprin-beta-1/2, SAM domain 3 (domain) [245-316]
- IPR029515: Liprin (family) [9-380]
- IPR001660: Sterile alpha motif domain (domain) [86-318]
- IPR037617: Liprin-beta-1/2, SAM domain 1 (domain) [86-149]
- IPR037618: Liprin-beta-1/2, SAM domain 2 (domain) [160-222]
- IPR013761: Sterile alpha motif/pointed domain superfamily (homologous_superfamily) [52-336]
Sequence:
MTNELSSTSSGTESSPQSPLTPDGKRSPKGIKKFWGKIRRTQSGNFNTDTPGMVEFRRGGLRATAGPRLSRTRDTKGQKCDANAPFAQWSTERVCTWLQDFGLAQYVIFARQWVASGHTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINTKQEEKSALLDHVWVTRWLDDIGLPQYKDQFYESRVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPNCLHRRPADESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNALIGPEAEQEKRDKMASPAYTPLTTTAKVRPRKLGFSHFGNMRKKKFDESTDYICPMEPGDAVSDSHRVYGVYRGLSPLDNHELDGLDQVGQIS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098793 (presynapse), GO:0030054 (cell junction), GO:0045202 (synapse)
Protein: Cadherin 10, isoform CRA_b (A6JMU7)
Organism: Rattus norvegicus (Rat)
Function: Cadherins are calcium-dependent cell adhesion proteins
Subcellular location: Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein
InterPro domains:
- IPR000233: Cadherin, Y-type LIR-motif (domain) [703-761]
- IPR039808: Cadherin (family) [23-763]
- IPR027397: Catenin binding domain superfamily (homologous_superfamily) [670-766]
- IPR020894: Cadherin conserved site (conserved_site) [238-468]
- IPR015919: Cadherin-like superfamily (homologous_superfamily) [59-568]
- IPR002126: Cadherin-like (domain) [50-584]
Sequence:
MKQELTFRRTPGLQQMTAESHVPRGDGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMNRENKEQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAVGSVKATDADTGKNAEVDYRIIDGDGTDMFDIITEKDTQEGIITVKKPLDYENRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSTSSPIRFTLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKETTRVSVFVRILDVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPRRTPTAPDNTDVRDFINERLKEHDLDPTAPPYDSLATYAYEGNDSVAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYGGGESDKDA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008013 (beta-catenin binding), GO:0019899 (enzyme binding), GO:0019900 (kinase binding), GO:0019901 (protein kinase binding), GO:1990782 (protein tyrosine kinase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007155 (cell adhesion), GO:0098609 (cell-cell adhesion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0016020 (membrane), GO:0098794 (postsynapse), GO:0048786 (presynaptic active zone), GO:0098793 (presynapse), GO:0071944 (cell periphery), GO:0030054 (cell junction), GO:0045211 (postsynaptic membrane), GO:0005886 (plasma membrane), GO:0042734 (presynaptic membrane), GO:0048787 (presynaptic active zone membrane), GO:0098590 (plasma membrane region), GO:0045202 (synapse), GO:0099572 (postsynaptic specialization), GO:0097060 (synaptic membrane), GO:0099634 (postsynaptic specialization membrane), GO:0098982 (GABA-ergic synapse), GO:0098978 (glutamatergic synapse)
Protein: Retinol binding protein 3, interstitial (A6KFT5)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR005151: Tail specific protease (domain) [109-1216]
- IPR029045: ClpP/crotonase-like domain superfamily (homologous_superfamily) [27-1229]
Sequence:
MMREWVLVLSTLLCVLAGPTHLFQPSLVLDMAKVLLDNYCFPENLMGMQAAIEQAMKSHEILGISDPQTLAHVLTVGVQSSLNDPRLFISYEPSTLEAPQQAPALTDLTREELLAQIQRNIRHEVLEDNVGYLRVDDLPGQEVLSELGEFLVSHVWKQLTGTSSLVLDLRHCAGGHVSGIPYVISYLHPGNTVLHVDTIYDRPSNTTTEIWTLPKVLGERYSADKDVVVLTSGHTGGVAEDIAYILKQMRRAIVVGERTEGGALDLQKLRIGQSDFFLTVPVSRSLGPLGGGGQTWEGSGVLPCVGIPAEQALEKALAILTLRRALPGVVLRLQEALQDYYTLVDRVPGLLHHLASMDYSAVVSEEDLVTKLNAGLQAVSEDPRLLVRATGPRETPSRPETGPNEPPAVTPEVPKEEDARRALVDSVFQVSVLPGNVGYLRFDRFADASVLKTLGPYVLRQVWEPLQDTEHLIMDLRHNPGGPSSAVPLVLSYFQGPEAGPVRLFTTYDRRTNITQEHFSHKELLGQRYGNRRGVYLLTSHRTATAAEEFAFLMQSLSWATLVGEITAGSLLHTCTVPLLDSPEGGLTLTVPVLTFIDNHGEAWLGGGVVPDAIVLAEEALERAQEVLDFHRSLGALVEGTGRLLEAHYARPEIAEQARDLLQSKLAQGAYRTAVDLESLASQLTADLQEVSEDHRLLVFHSPGELVAEEVPLPPPAIPSPEELSYLIEALFKTDVLPGHLGYLRFDAMAELETVKAIGPQLVRLVWQRLVDTAALVVDLRYNPGSYSSAVPLLCSYFFEEEPRQHLYSVFDRATSRVTEIWTLPLVAGQRYGSHKDLYILMSHTSGSAAEAFAHTMQDLQRATVIGEPTAGGALSVGIYQVDNSPLYASMPTQMALSATTGEAWDLAGVEPDITVPMSEALSTAQDIVALRAKVPTVLQTAGKLVADNYASPELGAKMAAKLSGLQSRYARVTSEGALAEMLGADLQMLSGDPHLKTAHIPEDAKDRIPGIVPMQIPSPEVFEDLIKFSFHTNVFEDNIGYLRFDMFGDCELLIQVSELLVEHIWKKIVHTDALIIDMRFNIGGPTSSISALCSYFFDEAPPVLLDKIYNRPNDSISELWTHSQLTGERYGSKKSVAILTSGVTAGAAEEFTYIMKRLGRALVVGEVTSGGCQPPQTYHVDDTHLYITIPTARSVGATDGSSWEGVGVTPNVVVSSELALTRAKEILQRALRA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:0008289 (lipid binding), GO:0019842 (vitamin binding), GO:0043178 (alcohol binding), GO:0019840 (isoprenoid binding), GO:0005501 (retinoid binding), GO:0019841 (retinol binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0006629 (lipid metabolic process), GO:0006720 (isoprenoid metabolic process), GO:0006721 (terpenoid metabolic process), GO:0016101 (diterpenoid metabolic process), GO:0001523 (retinoid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062023 (collagen-containing extracellular matrix)
Protein: Ubiquitin-like modifier-activating enzyme 5 (A0A2R8QGC0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Golgi apparatus
InterPro domains:
- IPR035985: Ubiquitin-activating enzyme-like (homologous_superfamily) [31-312]
- IPR045886: ThiF/MoeB/HesA family (family) [37-328]
- IPR029752: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 (conserved_site) [72-100]
- IPR000594: THIF-type NAD/FAD binding fold (domain) [49-300]
Sequence:
MATVEELKLRIRELENELIKSKQKQSDAEHNIRPKIEQMSAEVVDSNPYSRLMALKRMGIVQDYEKIRSFAVAVVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLFFQPHQAGLSKVEAAQHTLRNINPDVAFETHNYNITTMDNFTHFMDRVSHGGLEEGKPVDLILSCVDNFEARMAINTACNELGQIWMESGVSENAVSGHIQLIIPGETACFACAPPLVVAANIDEKTLKRDGVCAASLPTTMGVVAGLLVQNVLKYLLGFGTVSYYLGYNAMQDFFPSMAMKANPQCDDRHCRRQQDEYKKKEAERPKQEVVQEEEEVVHEDNEWGIELVSEVTEAELQDASGPIPDLPEGITVAYTIPEKDGGSGETVEETEQSLEELMAQMKKM
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0032501 (multicellular organismal process), GO:0007610 (behavior), GO:0007626 (locomotory behavior)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Eyes absent homolog (A0A8M6YVK2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
- IPR028472: Protein phosphatase EYA (family) [67-614]
- IPR038102: EYA domain superfamily (homologous_superfamily) [344-614]
- IPR042577: EYA domain, metazoan (domain) [343-614]
- IPR006545: EYA domain (domain) [344-613]
Sequence:
MEMQDLASPHSRVSGSSESPNGPNIDNSHINNNSMTPNGTEGDNITMLTTADWLLSSSSQSAAVKTEPMSSSEIATSVADGSLDSFSGSAIGTSGFSPRQTHQFSPQIYPSNRPYPHILPTPSAQNMAAYGQTQYTTGMQQAAAYGTYPQPGQPYGISAYGPLWAGIKTEGGLTQAQSPGQSGFLSYSSSFSTPQTGQAPYSYQMQGGSFTTTSGLYAGSNSLTNSTGFNSTQQDYPSYPTFGQSQYAQYYNSSPYTSPYMTSNNTSPTTPSTTATYTLQEPPSGITSQALTEQPTGEYSTIHSPSTPIKDSDSDRLRRASDVKARGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRFGRDPPTSVSLGLRMEEMIFNLADTHFFFNDLEECDQVHIDDVSSDDNGQDLSTYNFSTDGFHAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYTTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALTLIHSRSNCVNILVTTTQLIPALAKVLLYGLGVVFPIENIYSATKIGKESCFERVIQRFGRKVVYVVVGDGVEEEQGSKKHNMPFWRISSHSDLMALHHALDLEYL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0035295 (tube development), GO:0021984 (adenohypophysis development), GO:0048840 (otolith development), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0048729 (tissue morphogenesis), GO:0021536 (diencephalon development), GO:0009888 (tissue development), GO:0060322 (head development), GO:0030900 (forebrain development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009790 (embryo development), GO:0048839 (inner ear development), GO:0035239 (tube morphogenesis), GO:0035270 (endocrine system development), GO:0007420 (brain development), GO:0071599 (otic vesicle development), GO:0021983 (pituitary gland development), GO:0060562 (epithelial tube morphogenesis), GO:0048568 (embryonic organ development), GO:0042472 (inner ear morphogenesis), GO:0007399 (nervous system development), GO:0048562 (embryonic organ morphogenesis), GO:0007423 (sensory organ development), GO:0090596 (sensory organ morphogenesis), GO:0048732 (gland development), GO:0007417 (central nervous system development), GO:0002009 (morphogenesis of an epithelium), GO:0060429 (epithelium development), GO:0071600 (otic vesicle morphogenesis), GO:0042471 (ear morphogenesis), GO:0043583 (ear development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)