Protein: Retinoic acid receptor alpha 2 isoform (Q9QWJ1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR000536: Nuclear hormone receptor, ligand-binding domain (domain) [180-414]
- IPR047159: Retinoic acid receptor, DNA-binding domain (domain) [79-163]
- IPR013088: Zinc finger, NHR/GATA-type (homologous_superfamily) [80-176]
- IPR003078: Retinoic acid receptor (family) [57-418]
- IPR035500: Nuclear hormone receptor-like domain superfamily (homologous_superfamily) [134-418]
- IPR001628: Zinc finger, nuclear hormone receptor-type (domain) [82-157]
- IPR047158: Retinoic acid receptor, ligand-binding domain (domain) [183-413]
- IPR001723: Nuclear hormone receptor (family) [146-390]
Sequence:
MYESVEVGGLTPAPNPFLVVDFYNQNRACLLQEKGLPAPGPYSTPLRTPLWNGSNHSIETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKETPKPECSESYTLTPEVGELIEKVRKANQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDKVDMLQEPLLEALKVYVRKRRPSQPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGLDTLSGQSGGGTRDGGGLAPPPGSCSPSLSPSSHRSSPATQSP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0045182 (translation regulator activity), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0060089 (molecular transducer activity), GO:0030371 (translation repressor activity), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0090079 (translation regulator activity, nucleic acid binding), GO:0005515 (protein binding), GO:0038023 (signaling receptor activity), GO:0097159 (organic cyclic compound binding), GO:0003676 (nucleic acid binding), GO:0004879 (nuclear receptor activity), GO:0098531 (ligand-activated transcription factor activity), GO:0019899 (enzyme binding), GO:0000900 (mRNA regulatory element binding translation repressor activity), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific), GO:0003723 (RNA binding), GO:0042826 (histone deacetylase binding), GO:0003729 (mRNA binding), GO:0048027 (mRNA 5'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0048519 (negative regulation of biological process), GO:0009605 (response to external stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0051239 (regulation of multicellular organismal process), GO:0003006 (developmental process involved in reproduction), GO:0009892 (negative regulation of metabolic process), GO:0050793 (regulation of developmental process), GO:0065008 (regulation of biological quality), GO:0044706 (multi-multicellular organism process), GO:0050794 (regulation of cellular process), GO:0044703 (multi-organism reproductive process), GO:0023051 (regulation of signaling), GO:0051094 (positive regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0021766 (hippocampus development), GO:0045597 (positive regulation of cell differentiation), GO:0048167 (regulation of synaptic plasticity), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0021537 (telencephalon development), GO:0048731 (system development), GO:0008285 (negative regulation of cell population proliferation), GO:0048513 (animal organ development), GO:0060255 (regulation of macromolecule metabolic process), GO:0048608 (reproductive structure development), GO:1901700 (response to oxygen-containing compound), GO:0045137 (development of primary sexual characteristics), GO:0031324 (negative regulation of cellular metabolic process), GO:0010033 (response to organic substance), GO:0009991 (response to extracellular stimulus), GO:2000026 (regulation of multicellular organismal development), GO:0007565 (female pregnancy), GO:0042127 (regulation of cell population proliferation), GO:0010941 (regulation of cell death), GO:0007584 (response to nutrient), GO:0060322 (head development), GO:0010646 (regulation of cell communication), GO:0031641 (regulation of myelination), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0030900 (forebrain development), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0021543 (pallium development), GO:0045595 (regulation of cell differentiation), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0007548 (sex differentiation), GO:0099177 (regulation of trans-synaptic signaling), GO:0080090 (regulation of primary metabolic process), GO:0046661 (male sex differentiation), GO:0045664 (regulation of neuron differentiation), GO:0034097 (response to cytokine), GO:0097305 (response to alcohol), GO:0061458 (reproductive system development), GO:0045666 (positive regulation of neuron differentiation), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0032355 (response to estradiol), GO:0051246 (regulation of protein metabolic process), GO:0043067 (regulation of programmed cell death), GO:0051248 (negative regulation of protein metabolic process), GO:0050804 (modulation of chemical synaptic transmission), GO:0048732 (gland development), GO:0008406 (gonad development), GO:0046546 (development of primary male sexual characteristics), GO:0001655 (urogenital system development), GO:0051960 (regulation of nervous system development), GO:0033273 (response to vitamin), GO:0061008 (hepaticobiliary system development), GO:0010468 (regulation of gene expression), GO:0007420 (brain development), GO:0034248 (regulation of amide metabolic process), GO:0007399 (nervous system development), GO:0021761 (limbic system development), GO:0033993 (response to lipid), GO:0031667 (response to nutrient levels), GO:0030850 (prostate gland development), GO:0031326 (regulation of cellular biosynthetic process), GO:0007417 (central nervous system development), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0014070 (response to organic cyclic compound), GO:0010629 (negative regulation of gene expression), GO:0034249 (negative regulation of amide metabolic process), GO:0017148 (negative regulation of translation), GO:0042981 (regulation of apoptotic process), GO:0045471 (response to ethanol), GO:0033189 (response to vitamin A), GO:0008584 (male gonad development), GO:0001889 (liver development), GO:2000112 (regulation of cellular macromolecule biosynthetic process), GO:0006417 (regulation of translation), GO:2000113 (negative regulation of cellular macromolecule biosynthetic process), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0036477 (somatodendritic compartment), GO:0048471 (perinuclear region of cytoplasm), GO:0005737 (cytoplasm), GO:0120025 (plasma membrane bounded cell projection), GO:0097447 (dendritic tree), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043005 (neuron projection), GO:0043231 (intracellular membrane-bounded organelle), GO:0030425 (dendrite), GO:0005634 (nucleus)