lokahq/bioreason-rl huggingface dataset:
Protein: 2-oxoglutarate dehydrogenase complex component E1 (A0A8M2BJT5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Mitochondrion. Nucleus
InterPro domains:
- IPR029061: Thiamin diphosphate-binding fold (homologous_superfamily) [245-903]
- IPR031717: 2-oxoglutarate dehydrogenase E1 component/KDG, C-terminal (domain) [900-1045]
- IPR001017: Dehydrogenase, E1 component (domain) [289-613]
- IPR032106: 2-oxoglutarate dehydrogenase E1 component, N-terminal domain (domain) [49-87]
- IPR011603: 2-oxoglutarate dehydrogenase E1 component (family) [47-1046]
- IPR042179: Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily (homologous_superfamily) [814-1043]
- IPR005475: Transketolase-like, pyrimidine-binding domain (domain) [682-896]
Sequence:
MHRLRTCAARLRPITASQTAKNLSQQGPAATPRTFQPLRCFSSPVAAEPFLNGTSSNYVEEMYYAWLENPKSVHKSWDIFFRNANAGAPPGTAYQSPPPLGVSLAGLAQAQSLVGAQPNVEKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGIMDADLDSCVPTDIITSSDKLDLTHVKKRLSALTIGESEFHFAENSQICNWEKGFYGLEESDLDKVFRLPTTTFIGGDESALPLREIIRRLEMAYCQHIGVEFMFINDLDQCQWIRQKFERPGVMQFSLEEKRTLLARMVRSTRFEEFLQRKWSSEKRFGLEGCESLIPALKTIIDKSSENGVDTVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAADEGSGDVKYHLGMYHRRINRVTNRNITLSLVANPSHLEAVNPVVQGKTKAEQFYSGDTDGKRVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVANNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVMYVCNVAAEWRATFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIKKQKGVLQKYAEKLIAEGAVTRQEYEEEIAKYDKICEEAHSRSKDEKILHIKHWLDSPWPGFFTLDGQPKSISCPSTGLPEEELAQIGQVASSVPVEDFTIHGGLSRILKGRGDMIKNRTVDWALGEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQNVDKRICIPMNHMSPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDFNPKITDDFDVRQLYDCNWIVVNCSNPANYFHVIRRQILLPFRKPLIVFTPKSLLRHPEAKSNFDQMLPGTHFQRVITDDGPPAQNPSEVKRIVFCTGKIYYELTRERKARNMENSVAITRIEQLSPFPFDLVRAETEKFPNADLVWCQEEHKNQGYYDYVKPRMRTTINRTKPVWYAGREPAAAPATGNKNTHLLELKRFLDTAFNLDAFKDHI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016903 (oxidoreductase activity, acting on the aldehyde or oxo group of donors), GO:0016620 (oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0003008 (system process), GO:0003013 (circulatory system process), GO:0008015 (blood circulation), GO:0003015 (heart process), GO:0060047 (heart contraction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:1990204 (oxidoreductase complex), GO:0045254 (pyruvate dehydrogenase complex)
Protein: Prominin-1 isoform X4 (A0A8M9Q021)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell projection, microvillus membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein
InterPro domains:
Sequence:
MDMWWKVGLVLVMFWGLTSSEDREEHRESPPRTAMLRAPVETLDFGFVPSVVYETHAYYEPGPMGILFHMVHAFLYVVQPNPFPKDLIVKMVQQNMGGIKGDDYKKPENVVLLLQTIYYELGFIVLSVLGVFFVLLMPIVGLCFCVCRCCENCGGEMHQRQKKNGDCLRGFYMATLIATSVFLAVGVTVAYVANQNITSQIKSTRRLVSTNIRDLKAFANYTPAQIDYLTAQYTTAKNKVLSDLDNIGTLLGGQIHNKLESEVVPALDHALRMTAAMRETKESLESVSTSLETLQEGTGRLQVSLQSERVSLSNTLNDWACSNEDVTHTCNSIRGTLNQLALSANFNGLPDVEAPLANLDAVLKTDLSNIVQKGYSSFNDTPQLVREQTKGIVSALPKVKGLLDKSGAEIIGFTKMFPVEPALQNFSKFLTDSQKNIEAYYPQIDQLDFYRWIGCVLICCLVVLVLAFNFLGLLCGSCGYDKNSTPTTRGCLSNTGGNLLMASVGFSFIFSWVLMGVVVTTFIVGGNIEKLVCEPLANRQIFKIIDTPYMVHPTKKNFLPGMLFQDPNIDLTIGSMYRDCYENNGLYSALQLETKFNFNKFLNATVFNPEIGDIFNNVNVDLQGMLLLEQEGKDNLIDFANTGIGDIDYQAYLTEVNKGVTVVDLLSYANELDAQADNLPRGALENALKGHASSIRQIHKDQVVPMEQAMKFVKARSNLNQSIRQLEKTSRELPVKVTNVLNAIEAAEYLISNNASHVVKQESDKFIKKIIGYFSQYTEWVKHSLAMEVAQCKPISNIVDSAEIVACSFIVDSVNTFWFGLGGCCVLLIPSIIMSVKLAKFYRRMDTEDVFDDYPSYDTMRWYPRASAPPRQPDW
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0007276 (gamete generation), GO:0007281 (germ cell development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0007283 (spermatogenesis), GO:0048515 (spermatid differentiation), GO:0007286 (spermatid development), GO:0048232 (male gamete generation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0045177 (apical part of cell), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0016324 (apical plasma membrane)
Protein: Homeobox protein Meis2 isoform X1 (A0A8M3AK57)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
- IPR008422: KN homeodomain (domain) [302-341]
- IPR032453: Homeobox protein PKNOX/Meis, N-terminal (domain) [69-182]
- IPR001356: Homeodomain (domain) [282-349]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [283-354]
- IPR050224: Three Amino acid Loop Extension (TALE) homeobox (family) [58-354]
Sequence:
MAQRYDELAHYGGMDGVGMYGDPHAPRPLPQVHHLNHGPPLHASQHYGTHAPHPNVMPTSMGSAVNDVLKRDKDQIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHMGNGWIRSDRLQNPASWRDHDDATSTHSAGTPGPSSGGLASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009790 (embryo development), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:1904888 (cranial skeletal system development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048701 (embryonic cranial skeleton morphogenesis), GO:0048703 (embryonic viscerocranium morphogenesis), GO:0048705 (skeletal system morphogenesis), GO:0048568 (embryonic organ development), GO:0001501 (skeletal system development), GO:0048562 (embryonic organ morphogenesis), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development), GO:0048704 (embryonic skeletal system morphogenesis), GO:0048706 (embryonic skeletal system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: RNA binding motif protein 14 isoform X2 (A0A8M9Q7N4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
Sequence:
MDKGHTVKLFVGNLALDTTQEELSAIFESYGQVVSCSVLRQFAFVHLQGEGAAERAIRELNGREFKGRNLVVEESRGRPLHSTKVFVGNLSSMCTTEDLQELFQTFGKVLECDKVKGYAFVHMENKEDALQAIEALHGTSFKGRPLSVELSKVQPSKQTPTGKIPCVSCGKQGHYAGECPAGKPTLEQYQSQAAVLAAAAAAAAGLPLQVQQSVHNSVYNTSTFDPTYAALTGLTAAGARAEGGAAVAPAVYGALASQVYGTAVANQLYGGSVANQALNSSAAAAAAQAYGTVNPALYGQMTSGAVAAAAAAAAAYGPQVGFLVYTQAVGNPVFLTAAPSMEVPAGAAAVNPAYTVAPALYSATPAYGALGAADPAAIFEAARAHYFAQGQQVLAEQQQASSKSGERDRSPLRRSAPLLPDPVMKPFIYQRAKRRALLPTPAGREEAAAQEDDPVARYYAEYYQQYQQLQQYPQYQYAYPAHSALAAMSALQSLPGVSAQQVATLDSLRPVLPAAPVPAAAAIAMATPRVYEPPPIPPSHKEPLLRRPELALHTPETPFR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0009719 (response to endogenous stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0071495 (cellular response to endogenous stimulus), GO:0007166 (cell surface receptor signaling pathway), GO:0070848 (response to growth factor), GO:0007167 (enzyme-linked receptor protein signaling pathway), GO:0071772 (response to BMP), GO:0071363 (cellular response to growth factor stimulus), GO:0007178 (transmembrane receptor protein serine/threonine kinase signaling pathway), GO:0071773 (cellular response to BMP stimulus), GO:0030509 (BMP signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: F-actin-capping protein subunit beta (A0A8M3AUB3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments
Subcellular location: Cytoplasm, cytoskeleton
InterPro domains:
- IPR043175: F-actin-capping protein subunit beta, N-terminal domain (homologous_superfamily) [1-89]
- IPR037282: F-actin-capping protein subunit alpha/beta (homologous_superfamily) [3-266]
- IPR019771: F-actin capping protein, beta subunit, conserved site (conserved_site) [62-67]
- IPR001698: F-actin-capping protein subunit beta (family) [1-267]
- IPR042276: F-actin-capping protein subunit alpha/beta, domain 2 (homologous_superfamily) [90-244]
Sequence:
MNEQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYEPPIDDGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTTKTGSGTMNLGGSLTRQMEKDETVSESSPHIANIGRLVEEMENKIRSTLNEIYFGKTKDIVNGLRSIESLPDNQKYRQLQRELSQVLTQRQIYID
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0048870 (cell motility), GO:0061061 (muscle structure development), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048513 (animal organ development), GO:0016477 (cell migration), GO:0048863 (stem cell differentiation), GO:0048864 (stem cell development), GO:0060485 (mesenchyme development), GO:0048762 (mesenchymal cell differentiation), GO:0042692 (muscle cell differentiation), GO:0055001 (muscle cell development), GO:0001667 (ameboidal-type cell migration), GO:0014033 (neural crest cell differentiation), GO:0014032 (neural crest cell development), GO:0090497 (mesenchymal cell migration), GO:0001755 (neural crest cell migration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0030017 (sarcomere), GO:0031674 (I band), GO:0030018 (Z disc), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043292 (contractile fiber), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0030016 (myofibril), GO:0043232 (intracellular non-membrane-bounded organelle)
Protein: RNA helicase (A0A8M9Q4N8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm
InterPro domains:
- IPR001650: Helicase, C-terminal domain-like (domain) [565-726]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [286-731]
- IPR011545: DEAD/DEAH-box helicase domain (domain) [350-541]
- IPR014014: RNA helicase, DEAD-box type, Q motif (domain) [326-354]
- IPR000629: ATP-dependent RNA helicase DEAD-box, conserved site (conserved_site) [496-504]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [345-569]
Sequence:
MSHVVVDGSHGLDQQLAVLDLNSADGQGVGTGRRYIPPHLRNKDASKNAGNAYSSGRQSGYSVAPVQSFSPKQYPQSWHPEGNQRHRQNYPTGWNDFRTGSQRFASQELAFYHTYTSGWPDRCASPARTDSSVATDGNEDTASVISWADRCDSPGWDGSRTNGFVNGYHDSRMNGTANFARGPLRNDRGGRGGFRGNRNGASFNQPVHNAGYGTYENKDGGWNSVVNRDAYASFGGRSDRGKSAFFNDRGASSRGRYERGGFGGGTGGNSRWVEESRDEEDWSKPMPPNERLEHELFSASNTGINFEKYDDIPVEATGTNSPGHIESFHDVDMGEIIMGNITLSRYTRPTPVQKYAIPIIKTKRDLMACAQTGSGKTAAFLLPVLSQIYSEGPGEALQATKASTQQENGKYVRRKQYPISLVLAPTRELALQIYDEARKFAYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDYCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGSRQTMMFSATFPKEIQILARDFLEEYIFLAVGRVGSTSENITQKVVWVEENDKRSFLLDLLNATGKDSLTLVFVETKKGADALEDFLYREGYACTSIHGDRSQRDREEALHQFRSGRCPIMVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFYNDKNSNITKDLLDILVEAKQEVPSWLENLAYEHQHKSTNRGRPKRFSGGFGARDYRQMPGGGNTFGNRGARNTGGHGGNRGFGGNKGGFGSFGGDSYGGTYGNYGGNYTQVDWWGN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0048870 (cell motility), GO:0042221 (response to chemical), GO:0050900 (leukocyte migration), GO:0042330 (taxis), GO:0097529 (myeloid leukocyte migration), GO:0006935 (chemotaxis), GO:0030595 (leukocyte chemotaxis), GO:0070887 (cellular response to chemical stimulus), GO:0016477 (cell migration), GO:0071621 (granulocyte chemotaxis), GO:0060326 (cell chemotaxis), GO:0097530 (granulocyte migration), GO:1990266 (neutrophil migration), GO:0030593 (neutrophil chemotaxis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0043229 (intracellular organelle), GO:0035770 (ribonucleoprotein granule), GO:0036464 (cytoplasmic ribonucleoprotein granule), GO:0045495 (pole plasm), GO:0043228 (non-membrane-bounded organelle), GO:0043186 (P granule), GO:0060293 (germ plasm), GO:0043232 (intracellular non-membrane-bounded organelle)
Protein: Ligand of Numb protein X 2 isoform X3 (A0A8M9PU28)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
Sequence:
MGSLGEGVDPGMVSEALLEALCSECGQIHRTWENHLYNYRLEVDDDLVCHICLQPLVQPLDTPCGHTFCARCLRSFLQERDFCPLDRAHLQLQVCRRSSILVHKLLDKLSVTCPLTPSCSLSMPRCDLEAHLKHRCPGTQSQRTKLERTQMEGSEDRVTATNPPKSPQTEIKEDTPSPPAGSNACNNVPTWTEEPGIDNPAFEESTEEDSVHGLECALPRVKRPLSNPCIHLLRTGSSASSGWDFVETLPLSAEEGCVKLPSLPEGEITTIEVHRTNPYSEMGISIVGGNETPLINVVIQEVYRDGVIARDGRLLAGDQILQVNNVDISNVPHNFARSTLARPCATLQLTVLRERRCSARPPAATASPKGSPASIRITLHKRESSEQLGIKLVRRTDEAGVFILDLLEGGLAAKDGRLCSNDRVLAVNEHDLRHGTPELAAQIIQASGERVNLLISRSSKQTMAVHTGSTLTRDIWSHDHIPPLPSTATPSPVPSLHLARSSTQRDLSQCVNCKEKHITVKKEPHESLGMTVAGGRGSKSGELPIFVTSVQPHGCLSRDGRIKRGGL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity), GO:0061659 (ubiquitin-like protein ligase activity), GO:0061630 (ubiquitin protein ligase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048732 (gland development), GO:0035272 (exocrine system development), GO:0055123 (digestive system development), GO:0031016 (pancreas development), GO:0031017 (exocrine pancreas development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Receptor-type tyrosine-protein phosphatase epsilon isoform X1 (A0A8M9QJB7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR029021: Protein-tyrosine phosphatase-like (homologous_superfamily) [121-710]
- IPR000242: Tyrosine-specific protein phosphatase, PTPase domain (domain) [150-702]
- IPR000387: Tyrosine-specific protein phosphatases domain (domain) [330-691]
- IPR016130: Protein-tyrosine phosphatase, active site (active_site) [349-649]
- IPR003595: Protein-tyrosine phosphatase, catalytic (domain) [308-699]
- IPR050348: Protein-Tyrosine Phosphatase (family) [95-510]
Sequence:
MVLVLFLSVTTPQVTTNATENNHGDPGPFNTHILSILLGLSVLLLFLGLLTWYCLRLKNQRKAVITAVDKKVPNGILEEQEEYIDVDVDVDMDMDMDEDEDEDDLGWPSEEQQTVVLLPRSPSTSKTYLPIPVDNLEEEYRIRSADDGKLFREEYSSLPGGSIQGTCEEANKEENKEKNRYPNILPYDQSRVILTPMDGVTCSDYINASYIDGYKDKNKFIAAQGPKQDTTADFWRMIWEQKSSTIVMLTNLKERKEDKCYQYWPDQGCWTYGNVRVAVEDFTVLVDYTIRKFCVQYQASDGSKSPRLVTQLHFTSWPDFGVPFSPIGMLKFLKKVKQVNPSYAGPIVVHCSAGVGRTGTFIVIDAMIDMMHTEQKVDVFGFVSRIREQRSQLIQTDLQYSFVYQALLEYFLYGDTELDVSSLEGHLQKLHNTNAPLDRVGLEEEFKKLTNMRIMKENMRTGNLPANMKKNRVLQIIPYDFNRVILSMKRGQEFTDYVNASFIDGYRQKDYYIATQGPLVHTVDDFWRMAWEWKCHSIVMLTELQERDQDKCFQYWPSEDSVTYGEFSVEIKGDTLCETFSLRDLVLTHTPEKQTRLVRHFHFHGWPEIGIPAEGKGMIDIIAAVQKQQQQSGNHPIIVHCSAGAGRTGTFIALSNILERVKAEGLLDVFQTVKSLRMQRPHMVQTVEQYDFCYRVVQDFVDIFSDYANFK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0004721 (phosphoprotein phosphatase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0004725 (protein tyrosine phosphatase activity), GO:0016791 (phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009888 (tissue development), GO:0009790 (embryo development), GO:0048598 (embryonic morphogenesis), GO:0048729 (tissue morphogenesis), GO:0060429 (epithelium development), GO:0007369 (gastrulation), GO:0060027 (convergent extension involved in gastrulation), GO:0002009 (morphogenesis of an epithelium), GO:0060026 (convergent extension)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Cat eye syndrome critical region protein 2 isoform X2 (A0A8M1RL92)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR018359: Bromodomain, conserved site (conserved_site) [420-477]
- IPR036427: Bromodomain-like superfamily (homologous_superfamily) [384-506]
- IPR001487: Bromodomain (domain) [396-504]
- IPR029614: Chromatin remodeling regulator CECR2 (family) [2-1489]
Sequence:
MSQGCITSAEEIQSWWEVPAIAHFCSLFRTAFNLPDFEIEELEQALLKQDQDFLSVLLCSLLKGCYQRSDITIQSFSGYLEDIINYRWELEEGKPNPLKEHPFEELPTRTQVELLHRLCDYRLDAADVFDRLKGLDSDSLRVEPLGQDGNGALYWYFYGTRLYKEEPVEVVSPQYSNDKASEKKRRGRPPKNKPEDIDLSVVEEGVNSVKEEYERVEETKPAIERERGAWSVICETEEQWLNLAESIKDKISPQDRHLHRIITQNFLPEISNMIEHKEKELKQKLLNSPKEHNSQSEQHSSKDNWMQATTEEERQRDEDLERQVLLAEQRKEDERLLQEEREREEQERVKAVEERARRRKQREEKAWLLSQGKELPPELLNLETHSPIRRARRTKQFYEIDDDYTALYKVLEALKAHKDAWPFMEPVDESYAPNYHEIIQTPMDLSTIERKLNDGEYLAKDEFVADVKLMFGNCLEYNGEESEYTIMAESLERCFTRALLKHFPSEDGDTDEEFHVSSEDRKDKKKNKNHKQSGPESLIRATEQVQKRKTSNSGKGNNQQQEKPKSTLQPPPPHYSNGPPHPHNIHPGQQQRGMLHPAQQFQRPSGPGMYAQHMMIDAQYPYPGQRPLISRPPGDHENQHVPHFNMQGSHINGPHLGTRYTVGPDGQPLQPPHQQHSYSGPTHGPSLGPRPMALQPGGLCSPPPEGNMYPSHQHPEGQSMRPMGNAYTRPGVPMHSSYPPYGPHGMNIPRMWPPMNHQRQPTPSGNMMQEPSASGQHPYNHNMIHSQNSTGFTMANGQFKMPSANSQGPVGQKLQGGPQASRLHLASMLDSPEMIALQQLSASSSHHVGNFQSPQQSGGNPLASAEQSSPEKQLHMPSRDKQHTPVSSKGSSPKSGNKMSTGEISLTEAESRSYPSTTEKSEQPSQVTGLASVSSPSKELNQNEDKHRLSNLEKIHDQLNSQLGPPNLKSVDGFSFPLNSPQPMPHKTQDDIPLNISQQINKHALPQIIQNGSQRQSQNVPPQILQNIPQQMTENVIHQYHQSVSQQIQNNESVRGPQVGPLHGMPQISSQGGQPGVHQPATLSSLPPSHPVSHPLAQPSPADQGDQRPCEPTSRKVSDGSTASQDGSNANLRTDCTSGQYKQQPFSPESKPPLVRQEQAPLQNQTPPTHSQGPESNNVTHYGISEPAHQPFGPHHGRPLQTSNHQSYTSQGLPSHENNPNQNPAHYPAFHQQSIQYQYRMATQHSQGHPSMHPQFQQQQQFYQQQRHGRPVFPTEEWPRHPYQPQHPVMSNSYPTPSAGSFNGRHNDNGMSPHGSDGSVGSLMSPNLLPDGSHSSSFENKEDGSPAKQARTEEPSERSESPKEILDLDSHNATARHHTSAQPHSSFPYGPRGMHPSMQQSAAPPPHMMASGPYSSQQFSGGHFAPQNPHPHLMEALQRPQHLPFSPGQSRMTMYRHPNVAGHFQGMMVPQRAVVAEHLFRSGHQMLRTASPNGQGHKQGV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0030154 (cell differentiation), GO:0048468 (cell development), GO:0002244 (hematopoietic progenitor cell differentiation), GO:0030097 (hemopoiesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000785 (chromatin), GO:1902494 (catalytic complex), GO:0140513 (nuclear protein-containing complex), GO:0000791 (euchromatin), GO:0070603 (SWI/SNF superfamily-type complex), GO:0043229 (intracellular organelle), GO:1904949 (ATPase complex), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031010 (ISWI-type complex), GO:0005694 (chromosome), GO:0005634 (nucleus)