Protein: Two pore segment channel 2 (Predicted), isoform CRA_a (A6HYJ3)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR028798: Two pore channel protein 2 (family) [259-711]
- IPR005821: Ion transport domain (domain) [73-656]
- IPR027359: Voltage-dependent channel domain superfamily (homologous_superfamily) [54-527]
Sequence:
MAAEAQPLLGRDRGGGQAHSGADQELCIDQAVVFIEDAIKYRSIYHRLDAGSLWLYRWYYSNVCQRVLGFTIFLILALAFVEVPSSFTRTADVRYRSQPWQPPCGLTETIEALCLLVFLADLSVKGYLVGQAQLQQNLWLLAYFVVLVVSVVDWIVSLSLNCEESLRVRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLTIHLCLFTVIGMLLFTIAEKDEAQNKERLTYFRNLPEALTSLLVLLTTSNNPDGSLFLMNLLTAIIYNQFRGYLMKSLQTSLFRRRLGARAAYEVLTLQAGPNGTTSELVGVNPENFLRVLQKTQLNKIHKQAIIQKVHSYEGRPILADEFQKLFDEVDKGIVKERPPKPQYQSPFLQTAQFIFSHRYFDYLGNLIALGNLLSICVFLVLDSNLLPGERNDFVLGILNYIFILYYLLELLFKVFALGLRGYLFYHSNVFDGLLTIILLVLEISTLAVYRLPHPGWKPEQYGPLSLWDMTRLVNILIVIRFLRIIPSIKPTAVVASTILGLIQNLRAFGGILVVVYYVFAMIGINLFRGVIVPPGNSSLVPDNSSAPCGSFEQLGYWPNNFDDFAAALITLWDVMVVNNWQVILEAYKHYSGPWSMVYFVLWWLVSSVIWINLFLALLLENFLHRWDPQGHKQLLVGTKQITYEMSVELMFRDILEEPKEEELMEKLHKHPHLHLCR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0005515 (protein binding), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0042802 (identical protein binding), GO:0022803 (passive transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0015085 (calcium ion transmembrane transporter activity), GO:0015267 (channel activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0005261 (monoatomic cation channel activity), GO:0005262 (calcium channel activity), GO:0022839 (monoatomic ion gated channel activity), GO:0022836 (gated channel activity), GO:0046873 (metal ion transmembrane transporter activity), GO:0099094 (ligand-gated monoatomic cation channel activity), GO:0022834 (ligand-gated channel activity), GO:0099604 (ligand-gated calcium channel activity), GO:0015276 (ligand-gated monoatomic ion channel activity), GO:0005217 (intracellular ligand-gated monoatomic ion channel activity), GO:0015278 (calcium-release channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:0007584 (response to nutrient), GO:0009991 (response to extracellular stimulus), GO:0010033 (response to organic substance), GO:1901700 (response to oxygen-containing compound), GO:0033273 (response to vitamin), GO:0033993 (response to lipid), GO:0031667 (response to nutrient levels), GO:0033280 (response to vitamin D), GO:0014070 (response to organic cyclic compound)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0005773 (vacuole), GO:0043227 (membrane-bounded organelle), GO:0036019 (endolysosome), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0045009 (chitosome), GO:0098588 (bounding membrane of organelle), GO:0048770 (pigment granule), GO:0012506 (vesicle membrane), GO:0005774 (vacuolar membrane), GO:0010008 (endosome membrane), GO:0031982 (vesicle), GO:0030659 (cytoplasmic vesicle membrane), GO:0042470 (melanosome), GO:0005764 (lysosome), GO:0036020 (endolysosome membrane), GO:0090741 (pigment granule membrane), GO:0097708 (intracellular vesicle), GO:0098852 (lytic vacuole membrane), GO:0005765 (lysosomal membrane)