lokahq/bioreason-rl huggingface dataset:
Protein: Short stature homeobox protein isoform X1 (A0A8M2BFC1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
- IPR000047: Helix-turn-helix motif (conserved_site) [138-163]
- IPR017970: Homeobox, conserved site (conserved_site) [142-165]
- IPR003654: OAR domain (domain) [264-276]
- IPR001356: Homeodomain (domain) [107-171]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [105-172]
- IPR052631: Paired homeobox Bicoid subfamily (family) [1-276]
Sequence:
MEELTAFVSKSFDQKTKESSKESITYREVLESGLARARELGNSETNLQEITETNNNHCPVHLYKEHVELEKEKLKEFSVTRASDGIYDCKDKKEDVKSEDEDAQSKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVGTHSHPHLHPHLAAHAPYLMFPPPPFGLPIASLADSASAAAAVVAAAKSNSKNSSIADLRLKAGLLGGHWLSPFQAQITAPGPYKNVWMSV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0001503 (ossification), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0008283 (cell population proliferation), GO:0048736 (appendage development), GO:0030282 (bone mineralization), GO:0009888 (tissue development), GO:0048513 (animal organ development), GO:0031214 (biomineral tissue development), GO:0033333 (fin development), GO:0060173 (limb development), GO:0033339 (pectoral fin development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Non-muscle caldesmon isoform X2 (A0A8M9Q078)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR006017: Caldesmon (family) [345-497]
- IPR006018: Caldesmon/lymphocyte specific protein (family) [32-506]
Sequence:
MDDDFERRRELRRQKREEMRLEAERMAYRRSEEDEEEAARERRRRARQERMRSKDSEDVAFQPETPELNNSHSVTVSESISTSVLSSSGTGEGDEEEQALLERLAKREERRMRRMKEALERQKEDEEESSSSSLRRGRSYEPEEQHNNNNNQEEKEEEKQEEEEEEEDVRCREEEEEEEQRVEEKQQRSYLSERESVEEISKIPDEMEDEDVMRKNKQPNGGVCEDSPPKHKKAERTFSRGSLRSPEAPDADDEDARLEAERKLEELKRRRDEMESEEFEKMRQKQQEAEVELEELKRKREERRKVLEEEERRRKQDEADRKTREEEEKRRMKEEIEKRRAEAAEKRQKVEDSVDGEARKPFKCVSPRGSSLKIGERAEFLNRSAQKSSVKASHTPVVSKIDNRLEQYTTAVQGNKEVRSPRSGAIDLPMVTDGIRNIKSMFEKGNVFSSGGSPASTNKDAAGIKVGVAGRINDWLNKTPETGKMSGGRPADLKPGDVTSKRSLWENKGSSATKVTSRGETKSVTNGMGH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0017022 (myosin binding), GO:0003779 (actin binding), GO:0032036 (myosin heavy chain binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0003008 (system process), GO:0003012 (muscle system process), GO:0006936 (muscle contraction), GO:0006939 (smooth muscle contraction), GO:0014821 (phasic smooth muscle contraction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0005856 (cytoskeleton), GO:0099513 (polymeric cytoskeletal fiber), GO:0005884 (actin filament), GO:0015629 (actin cytoskeleton)
Protein: Follistatin-related protein 1 (A0A8M3BCA5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted
InterPro domains:
- IPR057020: Follistatin-related protein 1, EF-hand domain pair (domain) [111-230]
- IPR003645: Follistatin-like, N-terminal (domain) [28-51]
- IPR011992: EF-hand domain pair (homologous_superfamily) [140-220]
- IPR036058: Kazal domain superfamily (homologous_superfamily) [32-96]
- IPR002350: Kazal domain (domain) [51-98]
- IPR002048: EF-hand domain (domain) [191-226]
- IPR015369: Follistatin/Osteonectin EGF domain (domain) [29-50]
- IPR050653: Protease Inhibitors and Growth Factor Antagonists (family) [13-296]
Sequence:
MMFRCLPVFFLLAVVCCHAEEAQSKSKVCANVFCGAGRECAVNEKGEPSCLCIEQCKTHKRSVCGSNGKTYRNHCELHRDACLTGLKIQVAHDGHCKEKKKEKAAASPVVCYVADRNELRRRVIEWLQTEVVPDGWFTKGSNFTDILLKYFKNYDNGDSQLDSAELLKFIQHNETAVQMSSYAEEENNRLLRSLCVDALIELSDENADWKLSFDEFLNCLKPGFSPPEKKCALEDETYEDGAETQVECNRCVCACGNWVCTAMTCDEKTPVFDTEGDQEMTEEEWTRRVAELNKHQETVEKMKTSTKEV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0009987 (cellular process), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0048583 (regulation of response to stimulus), GO:0048869 (cellular developmental process), GO:0023051 (regulation of signaling), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0007389 (pattern specification process), GO:0050794 (regulation of cellular process), GO:0090287 (regulation of cellular response to growth factor stimulus), GO:0009790 (embryo development), GO:0003002 (regionalization), GO:0010646 (regulation of cell communication), GO:0030154 (cell differentiation), GO:0048513 (animal organ development), GO:0009966 (regulation of signal transduction), GO:0090092 (regulation of transmembrane receptor protein serine/threonine kinase signaling pathway), GO:0009953 (dorsal/ventral pattern formation), GO:0030510 (regulation of BMP signaling pathway), GO:0048568 (embryonic organ development), GO:0060034 (notochord cell differentiation), GO:0030903 (notochord development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Nucleoporin p58/p45 isoform X2 (A0A8M2B9L0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus, nuclear pore complex
InterPro domains:
- IPR024882: Nucleoporin p58/p45/NUP49 (family) [57-596]
Sequence:
MSSFNFGTTTLGTTGAPAAAGGGGFSFGAATSTPAAGTGGFSFGGFGAQTSTPAPATTSTTSTLGFGTSLFAQKPTTGFSLSTPASAAASTSGLSLGSLTTSTAASTGFSLGFGKPAASATPFSLTTTTASAPAATGLSLGSVLTSTVPQTSSTGFSLNLGAAAATSSAPASGFSFGSSLFSNPTLTGLGQSTLGGPLSLGGLVSTSVATTSAPAPSLGLGGVDFSTSSEKNTDKLSSTRPEDSKALKDENLPAPICQDVDNFQKFVKEQKQVQEEISRMSSKPILKVQEDIKMLRQLLSICASGLQRNSLSIDKLKLETSQELKNADIALRTQKTPPGLQHENTAPSDYFRALVEQFEVQLQQYRQQIEELENHLTTQGSGSHITPQDLSMAMQKLYQTFVALAAQLQGVHENVKTLKHQYLGYRRAFLEDSTDIFESKRVAGKKWQSSPRVTTGPAPFGSVPNAAAVAMAATLTQQQQPAPGPQAPLGASFGTPFSSGIGSSMGSSSLGAFGSGPGFGGVASGGLSFGFSSSKPSGGSLSAGFGTSNTSGFNFSNPGINASAGLTFGVSNTQTPGFGAGGPLLQLKKPPAGNKRGKR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009887 (animal organ morphogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0090596 (sensory organ morphogenesis), GO:0022008 (neurogenesis), GO:0007399 (nervous system development), GO:0048880 (sensory system development), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0007423 (sensory organ development), GO:0042461 (photoreceptor cell development), GO:0046530 (photoreceptor cell differentiation), GO:0048592 (eye morphogenesis), GO:0001654 (eye development), GO:0150063 (visual system development), GO:0048699 (generation of neurons), GO:0001754 (eye photoreceptor cell differentiation), GO:0042462 (eye photoreceptor cell development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0140513 (nuclear protein-containing complex), GO:0031975 (envelope), GO:0012505 (endomembrane system), GO:0005643 (nuclear pore), GO:0043229 (intracellular organelle), GO:0031967 (organelle envelope), GO:0005635 (nuclear envelope), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: calcium/calmodulin-dependent protein kinase (A0A8M9QE51)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [131-143]
- IPR000719: Protein kinase domain (domain) [13-271]
- IPR013543: Calcium/calmodulin-dependent protein kinase II, association-domain (domain) [415-542]
- IPR017441: Protein kinase, ATP binding site (binding_site) [19-42]
- IPR032710: NTF2-like domain superfamily (homologous_superfamily) [409-539]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [9-285]
Sequence:
MATTTCTRFTDEYQLYEELGKGAFSVVRRCVKLSTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLLFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKNAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAQEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLVSRNFSVGSRQTTAPASVTAAAAAVAAAAGTTAGLVEQAAKTLLNKKADVKPQTNSTKNSIVTSPKGNLPSPALEAQTTVIHNAVDGIKESSDSSNATVEDEEMKARKQEIIKITEQLIEAINNGDFEAYAKICDPGLTCFEPEALGNLVEGMDFHRFYFENLLSKNSKPIHTTILNPHVHLIGEEAACIAYIRLTQYVDGQGRPRSSQSEETRVWHRRDSKWQNVHFHCSGAPAAPLQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0006950 (response to stress), GO:0009628 (response to abiotic stimulus), GO:0070482 (response to oxygen levels), GO:0001666 (response to hypoxia), GO:0036293 (response to decreased oxygen levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Heterogeneous nuclear ribonucleoprotein A1 isoform X3 (A0A8M9QHJ0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR000504: RNA recognition motif domain (domain) [38-208]
- IPR034845: hnRNP A1, RNA recognition motif 1 (domain) [36-116]
- IPR035979: RNA-binding domain superfamily (homologous_superfamily) [34-238]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [25-204]
Sequence:
MPPAITPKKEREAESAVSHRVTAMSKEQQTPREPEQLRKLFIGGLSFETTDESLRAHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYSSVGEVDAAMDARPHKVDGRAVEPKRAVSREDSSKPGAHSTVKKMFVGGIKEDTDEEHLREYFGQFGKIDEVNIMTEKNSDKRRGFAFITFDDHDAVDRIVIQKYHTVNGHNCEVRKALSREEMNRVSMNSRGGRGGGGGSGGGNFGRGGGGGGGGGYGGGYGGGGGRGGGGGYGGGDGYNGYGGGNGISTDKSGYGGGGPNYGGNRGYGSGGGGGGGGGYGNQGGGYGGGGYDNYNNNGGGGGGGGNFGGGNFGGGGDYNDFGNYNNQSSSNYGPMKGGNYGGGGGGGGRSGGGPYGGGYGGGSGGGGGYGGGSGGGGGGYGGGSGGRRF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0040007 (growth), GO:0048589 (developmental growth), GO:0048856 (anatomical structure development), GO:0031099 (regeneration), GO:0042246 (tissue regeneration), GO:0031101 (fin regeneration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000785 (chromatin), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome)
Protein: Tropomyosin beta chain isoform X5 (A0A8M2B255)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytoskeleton
InterPro domains:
- IPR014751: DNA repair protein XRCC4-like, C-terminal (homologous_superfamily) [202-248]
- IPR000533: Tropomyosin (family) [8-248]
Sequence:
MASITSIEAVKRKIQTLQQQADDAEDRAEMLQREVDLERQCRERAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRATKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERSEERAEVAEAKSGDLEEELKNVTNNLKSLEAQAEKYSTKEDKYEEEIRVLTDKLKEAETRAEFAERSVAKLEKTIDDLEEKVAQAKEENLNMHQVLDQTLLELNNL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0051015 (actin filament binding), GO:0008092 (cytoskeletal protein binding), GO:0003779 (actin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0009653 (anatomical structure morphogenesis), GO:0030029 (actin filament-based process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0032989 (cellular component morphogenesis), GO:0016043 (cellular component organization), GO:0061061 (muscle structure development), GO:0044085 (cellular component biogenesis), GO:0030036 (actin cytoskeleton organization), GO:0010927 (cellular component assembly involved in morphogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0022607 (cellular component assembly), GO:0042692 (muscle cell differentiation), GO:0006996 (organelle organization), GO:0030239 (myofibril assembly), GO:0031032 (actomyosin structure organization), GO:0055001 (muscle cell development), GO:0097435 (supramolecular fiber organization), GO:0070925 (organelle assembly), GO:0007010 (cytoskeleton organization), GO:0014866 (skeletal myofibril assembly), GO:0051146 (striated muscle cell differentiation), GO:0055002 (striated muscle cell development), GO:0140694 (non-membrane-bounded organelle assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0030017 (sarcomere), GO:0005737 (cytoplasm), GO:0036379 (myofilament), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043292 (contractile fiber), GO:0043229 (intracellular organelle), GO:0005865 (striated muscle thin filament), GO:0043228 (non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0030016 (myofibril), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015629 (actin cytoskeleton)
Protein: Serine/threonine-protein kinase MAK isoform X4 (A0A8M9PFV2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [122-134]
- IPR000719: Protein kinase domain (domain) [4-285]
- IPR050117: Mitogen-activated protein (MAP) kinase (family) [3-345]
- IPR017441: Protein kinase, ATP binding site (binding_site) [10-33]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [1-286]
Sequence:
MNRYTTLKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWEECMNLREVKSLKKLNHANVVKLKEVIRENDHLYFVFEYMKENLYQLMKDRENKMFTENEIRNIMFQVLSGLAFVHKHGFFHRDMKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRWYRAPEVLLRSPVYSSPIDIWAVGCIMAELYTLRPLFPGNSEVDEIFKICQVLGTVKKSDWPEGHQLASAMNFRFPQCVPTPLKTLIPNATNEALDIMRDLLQWDPKKRPSAVKALRYPYFQVGQLLGPRPMTPDARKAPVKAVLPSELRSEMQSVSEPVLPSQTKGQSRNSHQPLQQIPLPQSLTQTDTVALHTQKVVGGENSLMGLKNGRRRWGQTNMKPSDSWDDSDCSDTAASLSKKPSKGPEEEKTTPQPKEQKPLYTFSTVTKLPNTSRLNQSDSSHQSTSSARQHYLRQSRYMPGNFVTTTYNLSGGYIPSFQKKEVGSVGQRIQLAPLGHQHALDLSATADCKTGKAKPSKSKPSSTVSVNDNSEDYDGWKRRAERTQLKGTSYSALGKNSANLITHAPSVQPVHGRIDWAAKYGSHR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0006996 (organelle organization), GO:0030030 (cell projection organization), GO:0022607 (cellular component assembly), GO:0044782 (cilium organization), GO:0070925 (organelle assembly), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0060271 (cilium assembly), GO:0120031 (plasma membrane bounded cell projection assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Bridging integrator 1b isoform X1 (A0A8M9PZM7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR004148: BAR domain (domain) [16-287]
- IPR001452: SH3 domain (domain) [497-568]
- IPR027267: AH/BAR domain superfamily (homologous_superfamily) [9-288]
- IPR003005: Amphiphysin (family) [1-567]
- IPR036028: SH3-like domain superfamily (homologous_superfamily) [493-567]
Sequence:
MAEVGKGVNAGKLASNVQKRLTRAQEKVMQKLGKADETKDTAFEEQVANFNKQMNEGTKLQKDLKAYLLAVKTMHECSKRLHDCLAEMYDPEWFGKEEVDSIAEEMIEKEMDNNLEDTDLLWQDFHEKLLDNAVISMDAYLAQFPDIKARIAKRERKLVDFDSARHHFASVQKGKKKDEAKIAKPLALVEKAAPVWAQGILTAHQIAQTNLTRNQAEEDLGRAQKVFEEINYDLQEELPTLWNSRVGLYVNTFRSVSGLEETFHRDMGKLNQNLSDIMTKLEEQRVAKKGVTTASTGKSDDAANHNQETSDAPKSPSKLRDVPPVSRPPRPASSQEVKPDKIINLFEDAEVSDSNTTTQPEQPAQSPAVSPSQQWDSDNEADAQPHGQPYAAPEWDDDVTPAVQSYEPPSWDEQDGAPAQSGWDGQTAAPAQPDWEDEHWDEEGSQVGQVQDTETNWANDAAQDWEAESEPPQWEELQSNEAPTVTNGSSDTELPPSVLFKVKTMHDYSATDSDELDLKAGDIVLVLPFANPDEADDGWLMGVKESHWLQNKNLLAKGVFPENFTQKL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0003008 (system process), GO:0003012 (muscle system process), GO:0003013 (circulatory system process), GO:0003015 (heart process), GO:0008015 (blood circulation), GO:0006936 (muscle contraction), GO:0006941 (striated muscle contraction), GO:0060047 (heart contraction), GO:0060048 (cardiac muscle contraction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0030017 (sarcomere), GO:0031674 (I band), GO:0030018 (Z disc), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043292 (contractile fiber), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0030016 (myofibril), GO:0043232 (intracellular non-membrane-bounded organelle)
Protein: Minor histocompatibility antigen H13 isoform X1 (A0A8M2B8N4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein; Lumenal side
InterPro domains:
- IPR006639: Presenilin/signal peptide peptidase (family) [69-340]
- IPR007369: Peptidase A22B, signal peptide peptidase (family) [33-354]
Sequence:
MADVEQTAPAPDGSSNGSDLVNGTAGRFVSSAEGTALAYGSLLLMALLPIFFGALRSVGCSKSKGSSDMPETITSRDAARFPIIASCTLFGLYLFFKVFSQEYVNMLLSMYFFVLGILALSHTMSPFMCRVFPANLSNKQYQLLFTQGSGESKEEIVNYEFDTKDLICLCISSVVGVWYVLKKHWIANNLFGLAFALNGVELLHLNNVSTGCILLGGLFVYDVFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLGASNFAMLGLGDIVIPGIFIALLLRFDVSLKKNTRTYFYTSFLAYIFGLGLTIFVMHTFKHAQPALLYLVPACVGFPVLVALVKGELTEMFSYESSDEVLPHTPRLTHFPNVSGSPASLADSMQHFQLSSPRRRQHHTPSDM
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0004175 (endopeptidase activity), GO:0070001 (aspartic-type peptidase activity), GO:0004190 (aspartic-type endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050794 (regulation of cellular process), GO:0010941 (regulation of cell death), GO:0043067 (regulation of programmed cell death), GO:1901214 (regulation of neuron death), GO:0043523 (regulation of neuron apoptotic process), GO:0042981 (regulation of apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)