Protein: Histone acetyltransferase (A6HJ54)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus
InterPro domains:
- IPR000182: GNAT domain (domain) [498-651]
- IPR016376: Histone acetyltransferase GCN5/PCAF (family) [1-832]
- IPR001487: Bromodomain (domain) [721-829]
- IPR016181: Acyl-CoA N-acyltransferase (homologous_superfamily) [498-653]
- IPR036427: Bromodomain-like superfamily (homologous_superfamily) [701-831]
- IPR037800: Histone acetyltransferase GCN5 (family) [64-828]
- IPR009464: PCAF, N-terminal (domain) [81-331]
- IPR018359: Bromodomain, conserved site (conserved_site) [745-802]
Sequence:
MAEPSQAPNPAPAAQPRPLQSPAPAPTSTPAPSPASAPTPAPTPAPAPAPAAAPAGSTGTGGAGVGSGGDPARPGLSQQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKCNGWKNPKPPTAPRMDLQQPAANLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDVENLFMSVHKEEDTDTKQVYFYLFKLLRKCILQMTRPVVEGSLGSPPFEKPNIEQGVLNFVQYKFSHLAPRERQTMFELSKMFLLCLNYWKLETPAQFRQRSQSEDVATYKVNYTRWLCYCHVPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPKFLSMLEEEIYGANSPIWESGFTMPPSEGTQLVPRPATVSATVVPSTPIFSPSMGGGSNSSLSLDSTGTEPMPGEKRKLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLLSANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIARLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHSILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIPYTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0019902 (phosphatase binding), GO:0019903 (protein phosphatase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0051240 (positive regulation of multicellular organismal process), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0051239 (regulation of multicellular organismal process), GO:0071704 (organic substance metabolic process), GO:0050793 (regulation of developmental process), GO:0051640 (organelle localization), GO:0048522 (positive regulation of cellular process), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0051716 (cellular response to stimulus), GO:0051094 (positive regulation of developmental process), GO:0044238 (primary metabolic process), GO:0045597 (positive regulation of cell differentiation), GO:1901564 (organonitrogen compound metabolic process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0051646 (mitochondrion localization), GO:0019538 (protein metabolic process), GO:0070848 (response to growth factor), GO:0071495 (cellular response to endogenous stimulus), GO:0060255 (regulation of macromolecule metabolic process), GO:0051130 (positive regulation of cellular component organization), GO:0043170 (macromolecule metabolic process), GO:0010033 (response to organic substance), GO:0009991 (response to extracellular stimulus), GO:0070887 (cellular response to chemical stimulus), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0045595 (regulation of cell differentiation), GO:0016043 (cellular component organization), GO:0080090 (regulation of primary metabolic process), GO:0051128 (regulation of cellular component organization), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0034097 (response to cytokine), GO:0031344 (regulation of cell projection organization), GO:0051246 (regulation of protein metabolic process), GO:0071310 (cellular response to organic substance), GO:1990089 (response to nerve growth factor), GO:0048311 (mitochondrion distribution), GO:0051147 (regulation of muscle cell differentiation), GO:0051149 (positive regulation of muscle cell differentiation), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0031346 (positive regulation of cell projection organization), GO:0031667 (response to nutrient levels), GO:0051247 (positive regulation of protein metabolic process), GO:0014070 (response to organic cyclic compound), GO:1905207 (regulation of cardiocyte differentiation), GO:0006996 (organelle organization), GO:0071363 (cellular response to growth factor stimulus), GO:0007005 (mitochondrion organization), GO:0031399 (regulation of protein modification process), GO:0051153 (regulation of striated muscle cell differentiation), GO:2000725 (regulation of cardiac muscle cell differentiation), GO:0043543 (protein acylation), GO:0018193 (peptidyl-amino acid modification), GO:0071345 (cellular response to cytokine stimulus), GO:0051155 (positive regulation of striated muscle cell differentiation), GO:0048312 (intracellular distribution of mitochondria), GO:0034612 (response to tumor necrosis factor), GO:1990090 (cellular response to nerve growth factor stimulus), GO:0031401 (positive regulation of protein modification process), GO:0031058 (positive regulation of histone modification), GO:0031056 (regulation of histone modification), GO:0006473 (protein acetylation), GO:0071356 (cellular response to tumor necrosis factor), GO:0018205 (peptidyl-lysine modification), GO:0018394 (peptidyl-lysine acetylation), GO:0006475 (internal protein amino acid acetylation), GO:0018393 (internal peptidyl-lysine acetylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000785 (chromatin), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus), GO:0005694 (chromosome)