Protein: GM2 activator protein (Q8CJH4)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR036846: GM2-AP, lipid-recognition domain superfamily (homologous_superfamily) [37-199]
- IPR028996: Ganglioside GM2 activator (family) [13-197]
- IPR003172: MD-2-related lipid-recognition domain (domain) [40-195]
Sequence:
MRRVPLLLVLGLLFVLGLLFAGPVAPSRLISKRPSQLGGFSWDNCDEGKDPAVIKSLTLQPDPIVVPGDVIVSAEGKTSIPLTSPQKVELTVEKEVAGFWVKIPCVEQLGSCTYENVCDLIDQYIPPGETCPEPLHTYGLPCHCPFKEGTYSLPSSNFTVPDLELPSWLSTGNYRIQSILSSGGKRLACIKIAASLKGR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0005215 (transporter activity), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0016787 (hydrolase activity), GO:0008289 (lipid binding), GO:0005319 (lipid transporter activity), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0008047 (enzyme activator activity), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds), GO:0060229 (lipase activator activity), GO:0016004 (phospholipase activator activity), GO:0015929 (hexosaminidase activity), GO:0004563 (beta-N-acetylhexosaminidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0044238 (primary metabolic process), GO:0065009 (regulation of molecular function), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0033036 (macromolecule localization), GO:0006807 (nitrogen compound metabolic process), GO:0010876 (lipid localization), GO:0044255 (cellular lipid metabolic process), GO:0050790 (regulation of catalytic activity), GO:0044093 (positive regulation of molecular function), GO:0043603 (amide metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006629 (lipid metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0006810 (transport), GO:0006672 (ceramide metabolic process), GO:0006869 (lipid transport), GO:0071702 (organic substance transport), GO:1903509 (liposaccharide metabolic process), GO:0006665 (sphingolipid metabolic process), GO:0043085 (positive regulation of catalytic activity), GO:0051336 (regulation of hydrolase activity), GO:0006643 (membrane lipid metabolic process), GO:0051345 (positive regulation of hydrolase activity), GO:0001573 (ganglioside metabolic process), GO:0006664 (glycolipid metabolic process), GO:0006687 (glycosphingolipid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098552 (side of membrane), GO:0045178 (basal part of cell), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0045177 (apical part of cell), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0005773 (vacuole), GO:0009925 (basal plasma membrane), GO:0098590 (plasma membrane region), GO:0043229 (intracellular organelle), GO:0098562 (cytoplasmic side of membrane), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0016324 (apical plasma membrane), GO:0009898 (cytoplasmic side of plasma membrane), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0016323 (basolateral plasma membrane), GO:0005764 (lysosome)