Protein: H(+)-transporting two-sector ATPase (A6IR15)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein
InterPro domains:
- IPR055190: ATP synthase A/B type, C-terminal domain (domain) [463-562]
- IPR036121: ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily (homologous_superfamily) [15-86]
- IPR005725: ATPase, V1 complex, subunit A (family) [18-609]
- IPR004100: ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (domain) [22-83]
- IPR020003: ATPase, alpha/beta subunit, nucleotide-binding domain, active site (active_site) [446-455]
- IPR031686: ATPsynthase alpha/beta subunit, barrel-sandwich domain (domain) [124-212]
- IPR000194: ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (domain) [230-455]
- IPR022878: V-type ATP synthase catalytic alpha chain (family) [6-617]
- IPR023366: ATP synthase subunit alpha, N-terminal domain-like superfamily (homologous_superfamily) [17-86]
- IPR024034: ATPase, F1/V1 complex, beta/alpha subunit, C-terminal (homologous_superfamily) [456-609]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [88-460]
Sequence:
MDFSKLPKIRDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPRGVNVSALSRDIKWEFIPSKNLRVGSHITGGDIYGIVNENSLIKHKIMLPPRSRGSVTYIAPPGNYDASDVVLELEFEGVKEKLSMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMISFYDMARRAVETTAQSDNKITWSIIREHMGEILYKLSSMKFKDPVKDGEAKIKADYAQLLEDMQNAFRSLED
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042592 (homeostatic process), GO:0048878 (chemical homeostasis), GO:0009628 (response to abiotic stimulus), GO:0019725 (cellular homeostasis), GO:0042221 (response to chemical), GO:0050801 (monoatomic ion homeostasis), GO:0055082 (intracellular chemical homeostasis), GO:0098771 (inorganic ion homeostasis), GO:0010035 (response to inorganic substance), GO:0010033 (response to organic substance), GO:0009314 (response to radiation), GO:0010038 (response to metal ion), GO:0009416 (response to light stimulus), GO:0055080 (monoatomic cation homeostasis), GO:0006873 (intracellular monoatomic ion homeostasis), GO:0010212 (response to ionizing radiation), GO:0033993 (response to lipid), GO:0055074 (calcium ion homeostasis), GO:0006874 (intracellular calcium ion homeostasis), GO:0010042 (response to manganese ion), GO:0030003 (intracellular monoatomic cation homeostasis), GO:0071287 (cellular response to manganese ion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0098793 (presynapse), GO:0019898 (extrinsic component of membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0030054 (cell junction), GO:0031090 (organelle membrane), GO:0008021 (synaptic vesicle), GO:0031312 (extrinsic component of organelle membrane), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0043227 (membrane-bounded organelle), GO:0030133 (transport vesicle), GO:0070382 (exocytic vesicle), GO:0030672 (synaptic vesicle membrane), GO:0030658 (transport vesicle membrane), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0031982 (vesicle), GO:0012506 (vesicle membrane), GO:0030659 (cytoplasmic vesicle membrane), GO:0098850 (extrinsic component of synaptic vesicle membrane), GO:0099501 (exocytic vesicle membrane), GO:0097708 (intracellular vesicle)