Protein: protein-tyrosine-phosphatase (A6JX03)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Single- pass type I membrane protein
InterPro domains:
- IPR029021: Protein-tyrosine phosphatase-like (homologous_superfamily) [691-1269]
- IPR003961: Fibronectin type III (domain) [225-428]
- IPR000998: MAM domain (domain) [1-128]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [127-429]
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [224-422]
- IPR000242: Tyrosine-specific protein phosphatase, PTPase domain (domain) [716-1267]
- IPR000387: Tyrosine-specific protein phosphatases domain (domain) [891-1256]
- IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [3-126]
- IPR057598: Receptor-type tyrosine-protein phosphatase U-like, Fn3 domain (domain) [424-565]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [129-232]
- IPR016130: Protein-tyrosine phosphatase, active site (active_site) [910-1214]
- IPR007110: Immunoglobulin-like domain (domain) [130-221]
- IPR003595: Protein-tyrosine phosphatase, catalytic (domain) [869-1264]
- IPR050348: Protein-Tyrosine Phosphatase (family) [289-1081]
Sequence:
MLDPAVPTGSFMMVNSSGRASGQKAHLLLPTLKENDTHCIDFHYYFSSRDRSSPGALNVYVKVNGGPQGNPVWNVSGVVTEGWVKAELAISTFWPHFYQVIFESVSLKGHPGYIAVDEVRVLAHPCRKAPHFLRLQNVEVNVGQNATFQCIAGGKWSQHDKLWLQQWNGRDTALMVTRVVNHRRFSATVSVADTSQRSVSKYRCVIRSDGGSGVSNYAELIVKEPPTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGTWAETHIVDSPNYKLWHLDPDVEYEIRVLLTRPGEGGTGPPGPPLTTRTKCAVPGAVPLESIQGGPFEEKIYIQWKPPNETNGVITLYEINYKAVGSLDPSADLSSQRGKVFKLRNETHHLFVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKISAPSMPEYDADSPLNETDTTITVMLKPAQSRGAPVSVYQLVVKEERLQKSRRAADIIECFSVPVSYRNASNLDSLHYFAAELKPSNLPVTQPFTVGDNKTYNGYWNPPLSPLKSYSIYFQALSKANGETKINCVRLATKGASTQNSNTVEPEKQVDNTVKMAGVIAGLLMFIIILLGVMLTIKRRKLAKKQKETQSGAQREMGPVASTDKPTTKLSTNRNDEGFSSSSQDVNGFTDGSRGELSQPTLTIQTHPYRTCDPVEMSYPRDQFQPAIRVADLLQHITQMKRGQGYGFKEEYEALPEGQTASWDTAKEDENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGESSNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTAQLCMQYWPEKTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKAVRRLEKWQEEYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0004721 (phosphoprotein phosphatase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0050839 (cell adhesion molecule binding), GO:0019899 (enzyme binding), GO:0045296 (cadherin binding), GO:0004725 (protein tyrosine phosphatase activity), GO:0019900 (kinase binding), GO:0042578 (phosphoric ester hydrolase activity), GO:0019901 (protein kinase binding), GO:0016791 (phosphatase activity), GO:0051019 (mitogen-activated protein kinase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0065008 (regulation of biological quality), GO:0050794 (regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0050803 (regulation of synapse structure or activity), GO:0050807 (regulation of synapse organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0098794 (postsynapse), GO:0071944 (cell periphery), GO:0045211 (postsynaptic membrane), GO:0098590 (plasma membrane region), GO:0045202 (synapse), GO:0005886 (plasma membrane), GO:0099572 (postsynaptic specialization), GO:0097060 (synaptic membrane), GO:0099634 (postsynaptic specialization membrane), GO:0098984 (neuron to neuron synapse), GO:0014069 (postsynaptic density), GO:0098978 (glutamatergic synapse), GO:0032279 (asymmetric synapse), GO:0098839 (postsynaptic density membrane)