Protein: Chloride channel, voltage-sensitive 2b isoform X1 (A0A8M3AV81)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
- IPR014743: Chloride channel, core (homologous_superfamily) [82-575]
- IPR001807: Chloride channel (family) [155-574]
- IPR046342: CBS domain superfamily (homologous_superfamily) [575-856]
- IPR050970: Voltage-gated chloride channel (family) [15-876]
Sequence:
MAVDGQEQRALQYEQTLMYGRYTQELGVYAREEAARLREDGRQRRSISERSPSLKLLEYEKGRCVKCRRFAYASAPPDFFSVCAVHCQRFLMSRVGEDWIFLILLGLVMALVSFVMDFCIALLLQAQKWMYGGLDSNVVLQYLAWVTYPVVLISFSAGFTHIVAPQAAGSGIPEMKTILRGVVLKEYLTLKTFVAKVVGLTCALGSGLPLGKEGPFVHIASLCAALLCKFMSFFGGIYENESRNIEMLAAACAVGVGCCFAAPIGGVLFSIEVTSTFFAVRNYWRGFFAATFSAFIFRVLAVWNRDEETITALFKTRFRLDFPFDLQELPAFAVIGIASGFGGALFVYLNRLIVQFMRKQKTINKFLMKKRLLYPALVTLLISTLSFPPGFGQFMAGQLTQKETLVSFFDNRTWAKQGISEDFTFDTHLMAWKHPQANVFIILVIFIIMKFWMSALATTLPVPCGAFMPVFVIGAAFGRLVGESMAAWFPEGINTDGTIYPIVPGGYAVVGAAALSGAVTHTVSTAVIVFELTGQISHILPIMIAVILANAVAQSLQPSIYDSIIRIKKLPYLPELGWGHHEKYNIRVEDIMVRDVRYITLNSTYRDLQDILTIGNLKTVALVESADSMILLGSIERAQLQALLVQQVSRVRRQEVMRERAETERKRMSVASSPSSDDSSQKVNQEVRFQISTEESTFVPVRPISPKPLKPALKRTSVAEKNIEIPTSPHDSSMGLKNLLCARPQTDVMEESNNVELRQSKRVRISLLDDPDAEDDMTLGEIEEWEEQQLDEQVNFNSCKIDPAPFQLVERTSLHKTHTIFSLLGLDHAYVTSIGRLIGVVSLRELRKAIEGSMTVKGVKVRPPLASFRDSGTSGTSSESEATELHKLWDRHSSLSLPRDQQNHNTDNKTH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0008509 (monoatomic anion transmembrane transporter activity), GO:0015267 (channel activity), GO:0015108 (chloride transmembrane transporter activity), GO:0015103 (inorganic anion transmembrane transporter activity), GO:0005253 (monoatomic anion channel activity), GO:0005254 (chloride channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0031018 (endocrine pancreas development), GO:0035270 (endocrine system development), GO:0003309 (type B pancreatic cell differentiation), GO:0002064 (epithelial cell development), GO:0060429 (epithelium development), GO:0031016 (pancreas development), GO:0030855 (epithelial cell differentiation), GO:0002066 (columnar/cuboidal epithelial cell development), GO:0003323 (type B pancreatic cell development), GO:0002065 (columnar/cuboidal epithelial cell differentiation), GO:0002068 (glandular epithelial cell development), GO:0002067 (glandular epithelial cell differentiation), GO:0035883 (enteroendocrine cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction)