Protein: Transient receptor potential cation channel subfamily V member 4 isoform X2 (A0A8M2BCE0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
- IPR008347: Transient receptor potential cation channel subfamily V member 1-4 (family) [187-804]
- IPR005821: Ion transport domain (domain) [483-734]
- IPR002110: Ankyrin repeat (repeat) [246-407]
- IPR036770: Ankyrin repeat-containing domain superfamily (homologous_superfamily) [157-461]
- IPR008348: Transient receptor potential cation channel subfamily V member 4 (family) [81-669]
- IPR024862: Transient receptor potential cation channel subfamily V (family) [98-840]
Sequence:
MTDGFSASTLLKRYRLAMTESLSVSSPPDNSAQDSSEAADGDPNFPMSSMAALLENDDVSQPTHELPRPGQQNDQKQNMRIRFPGPFKKGVPNPMDLLESDYTEYPKQAPMDSMFDYGTCRQINNNKKGRRKKLPRGKAEIGMSCDEGSPEPPVLKVFNRWMLFEAVSRADPRALDGLLQYLQSHEKRLTDEEFKELSTGKTCLPKALLNLHNGQNDTIPILVDIAEQTGNLREFINTPFRDVYYRGQMALHIAIERRCKQYVELLVEKGADVHAQARGRFFQPRDEGGYFYFGELPLSLAACTNQPDMVHYLTENGHKKADLRRQDSRGNTVLHALVHIADNTRDNTRFVTKMFDLLLIKCAKLYPDCNLENILNNDGMSPLMMAAKLGKIGVFQHIIRREIKDEEARHLSRKFKDWAYGPVYSNLYDLSSLDTCGEEVSVLEILVYNSKIENRHEMLAVEPINELLRAKWQKFAAVTFYISVFSYLVTMIIFTLVAYYRPSVGKPPYAYDTTEDKVRLAGEIITVGSGLFFFVTNIKDLFLKKCPGVNSIFVDGSFQLLYFIYSVLVLVSAALYLSGIEAYVSVMVFALTLGWMNTLYFTRGLKLTGTYSIMIQKILIKDLFRFLLVYVLFMIGYASALVSLLTICPDKDTCKENCPTYPECRDTNTFSEFLLDLFKLTIGIGDLDNMLKGAQYPAVFLILLVTYIILTFVLLLNMLIALMGETVGQVSKESKKIWKLQWATTILDIERSFPVCLRRSFRVGEMVTVGKGLDGKPDKRWCFRVDEVKWSHWNQNLGIINEDPGQKDLSEHTQGGRGLRRDRWSTVVPRVVELNRGSRDHTVEMEPLTGRHRLKSES
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0015085 (calcium ion transmembrane transporter activity), GO:0015267 (channel activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0005261 (monoatomic cation channel activity), GO:0005262 (calcium channel activity), GO:0046873 (metal ion transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0006950 (response to stress), GO:0006970 (response to osmotic stress), GO:0003170 (heart valve development), GO:0048513 (animal organ development), GO:0034405 (response to fluid shear stress), GO:0033554 (cellular response to stress), GO:0048731 (system development), GO:0003171 (atrioventricular valve development), GO:0071498 (cellular response to fluid shear stress), GO:0072359 (circulatory system development), GO:0007507 (heart development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0045177 (apical part of cell), GO:0042995 (cell projection), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098590 (plasma membrane region), GO:0120025 (plasma membrane bounded cell projection), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0016324 (apical plasma membrane), GO:0005929 (cilium)