lokahq/bioreason-rl huggingface dataset:
Protein: Nucleoporin p58/p45 isoform X3 (A0A8M2B9X4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus, nuclear pore complex
InterPro domains:
- IPR024882: Nucleoporin p58/p45/NUP49 (family) [57-565]
Sequence:
MSSFNFGTTTLGTTGAPAAAGGGGFSFGAATSTPAAGTGGFSFGGFGAQTSTPAPATTSTTSTLGFGTSLFAQKPTTGFSLSTPASAAAASTSGLSLGSLTTSTAASTGFSLGFGKPAASATPFSLTTTTASAPAATGLSLGSVLTSTVPQTSSTGFSLNLGAAAATSSAPASGFSFGSSLFSNPTLTGLGQSTLGGPLSLGGLVSTSVATTSAPAPSLGLGGVDFSTSSEKNTDKLSSTRPEDSKALKDENLPAPICQDVDNFQKFVKEQKQVQEEISRMSSKPILKVQEDIKMLRQLLSICASGLQRNSLSIDKLKLETSQELKNADIALRTQKTPPGLQHENTAPSDYFRALVEQFEVQLQQYRQQIEELENHLTTQGSGSHITPQDLSMAMQKLYQTFVALAAQLQGVHENVKTLKHQYLGYRRAFLEDSTDIFESKRVAGKKWQSSPRVTTGPAPFGSVPNAAAVAMAATLTQQQQPAPGPQAPLGASFGTPFSSGIGSSMGSSSLGGFGTSNTSGFNFSNPGINASAGLTFGVSNTQTPGFGAGGPLLQLKKPPAGNKRGKR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0035295 (tube development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0061009 (common bile duct development), GO:0048732 (gland development), GO:0061008 (hepaticobiliary system development), GO:0001889 (liver development), GO:0035622 (intrahepatic bile duct development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0140513 (nuclear protein-containing complex), GO:0031975 (envelope), GO:0012505 (endomembrane system), GO:0005643 (nuclear pore), GO:0043229 (intracellular organelle), GO:0031967 (organelle envelope), GO:0005635 (nuclear envelope), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Neural cell adhesion molecule 1b isoform X18 (A0A8M3APP3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: This protein is a cell adhesion molecule involved in neuron- neuron adhesion, neurite fasciculation, outgrowth of neurites, etc
InterPro domains:
Sequence:
MFPTKAIILVLLFFDNAVSLQVDITPAHGEISVGESRFFLCEVIGGAKEIDWFAPAGEKIEPGRPDISVIRNDETSSTLTIYNAKVDNAGTYRCVASSGDQDAEATVNLKIYQKITFTNVPSPQEFTEGDNAIIVCDVISSPPPTVLWKYKGAKIQFDKDVRFKTLSNNHLQIRGIRKTDEGVYTCEGRIKARGEVDFRSIKVVVNVLPTIRIRQAETNATADMGFSTLLACDPDGFPEPIVTWRRNNAPLESGNKYSFNEDGSEMTVLDVTKLDEGDYTCIAKNKAGESEQELSLKVFVQPKITYLESQTTTEMDEQVTLTCEATGDPTPTITWSFGTRVFTEGEQEQQKRIYQASWTRPEQHKGPDGEVLVRSDARVSSLTLKYPQYTDAGQYLCTARNAIGETVQPVSLEVRYAPKILGSVAVYTWEGNPANISCEVLAHPSDVSITWLRDGFQLPNANTSNIKIHNTPSASYLEVNPESQSDFGNYNCTTSNEIGTESREFIMIPADVPSAPSIGEVQPYSSTAQVLFEEPESTGGVPVLKYRAEWRAVGRGKWVQRVYEVKDGLSSVTVTGLKPETDYEVKMSAINGKGEGDSSPSMVFKTEHVRYSYTNGIFHFHTEDTEGEPSPPILEGTLQPKGNSLKVKWIKQDDGGSPITHYLVRYKAREDSEWKPEIRLPSGSEYVMLIGLDWDTEYDVFVVAENQQGKSKPGTLTFRTSSEPTATTVSLSGSSVSSALASLLLSPVLLLLL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0042221 (response to chemical), GO:0042330 (taxis), GO:0071840 (cellular component organization or biogenesis), GO:0032989 (cellular component morphogenesis), GO:0000902 (cell morphogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0016043 (cellular component organization), GO:0006935 (chemotaxis), GO:0022008 (neurogenesis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0097485 (neuron projection guidance), GO:0032990 (cell part morphogenesis), GO:0048858 (cell projection morphogenesis), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0007411 (axon guidance), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0048812 (neuron projection morphogenesis), GO:0061564 (axon development), GO:0007409 (axonogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: 5,6-dihydroxyindole-2-carboxylic acid oxidase (A0A8M9Q985)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Melanosome membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein
InterPro domains:
- IPR002227: Tyrosinase copper-binding domain (domain) [100-332]
- IPR050316: Tyrosinase and Hemocyanin (family) [27-383]
- IPR008922: Di-copper centre-containing domain superfamily (homologous_superfamily) [41-393]
Sequence:
MIQSPEILSRRADVHVQRSGPGDVEQCSGSRVCGGHAEISGHALAVRRNVLTLSAEQKRVFVSALDQAKRTTHPDIVIATRHYSEIFGPDNSTQFQNISIYNLFVWTHYYSVSKTFLGDGEPSFSAVDFSHEGPGFLTWHRYHLLQLERDMQDMLRDPSFALPFWDFSTGGSECDICTDDLMGARSRFDSTAISSNSIFSSWRVICESVEDYDTLGTICNSTESSPIRRNPAGNVARPMVQRLPEAQDVAACLEIDAFDTPPFYSTSSDSFRNSIEGYSAPEGPYDPVVRSLHNLAHLFLNGTGGQTHLSPNDPIFLLLHTFTDAIFDEWLRRHTADVSSYPLENAPIGHNREFNMVPFWPPVRNAEMFVSAADSLGYSYEVQWPARALTLTQIITVTVVAALIIVAIVFAAATCVVRSRSFGTETRQPLLGDQYQRYDEQHKTQSVV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0046983 (protein dimerization activity), GO:0042803 (protein homodimerization activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0043473 (pigmentation), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0071840 (cellular component organization or biogenesis), GO:0048066 (developmental pigmentation), GO:0033059 (cellular pigmentation), GO:0016043 (cellular component organization), GO:0050931 (pigment cell differentiation), GO:0048753 (pigment granule organization), GO:0009888 (tissue development), GO:0060041 (retina development in camera-type eye), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0030318 (melanocyte differentiation), GO:0007423 (sensory organ development), GO:0060429 (epithelium development), GO:0006996 (organelle organization), GO:0048880 (sensory system development), GO:0003406 (retinal pigment epithelium development), GO:0032438 (melanosome organization), GO:0016050 (vesicle organization), GO:0001654 (eye development), GO:0150063 (visual system development), GO:0043010 (camera-type eye development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0048770 (pigment granule), GO:0031982 (vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0042470 (melanosome), GO:0097708 (intracellular vesicle)
Protein: Rho guanine nucleotide exchange factor 9 (A0A8M9QP60)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Acts as a guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters
InterPro domains:
- IPR035728: Rho guanine nucleotide exchange factor 9, SH3 domain (domain) [574-635]
- IPR000219: Dbl homology domain (domain) [673-857]
- IPR001849: Pleckstrin homology domain (domain) [888-997]
- IPR001452: SH3 domain (domain) [575-634]
- IPR035899: Dbl homology (DH) domain superfamily (homologous_superfamily) [663-879]
- IPR055251: SOS1/NGEF-like, PH domain (domain) [883-992]
- IPR036028: SH3-like domain superfamily (homologous_superfamily) [560-681]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [880-1033]
Sequence:
MRNSSTGSNRRKLFRPGSGPLHVNMLISGGSVVSAEAVWDHVTMAERELAFKAGDVIKVLDASNKDWWWGQIDDEEGWFPASFVRLWVNQENIATESAEGASEVQNGHTDPSNGCLCIGQPLQNRDQMRANVINEIMSTERHYIKHLKDICEGYLRQCRKRIDMFNDDQLKVIFGNIEDIYRFQMGFVRDLEKQYNIEEPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKLMKDGRYQHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQEHSDYRYVAAALAVMRNVTQQINERKRRLENIDKIAQWQASVLDWEGDDILDRSSELIYTGEMSWIYQPYGRSQQRVFFLFDHQLVLCKKDLIRRDILYYKGRIDMDRYAVRDAIDGRDDDFNVSVKNAFKLHNRDSDEIHIFLAKKPEEKIRWLRAFHEERKMVQEDEKIGFEISEYQKKQAAMTVRKVTKQKGVSQSRCVSPSDPSSHGPFVLSDDMQQSDLVEFHVSKSGQSPFWQNFNKFTSKNGKK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0016043 (cellular component organization), GO:0035239 (tube morphogenesis), GO:0044085 (cellular component biogenesis), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0030030 (cell projection organization), GO:0048514 (blood vessel morphogenesis), GO:0002040 (sprouting angiogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development), GO:0022607 (cellular component assembly), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0120031 (plasma membrane bounded cell projection assembly), GO:0046847 (filopodium assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0035770 (ribonucleoprotein granule), GO:0036464 (cytoplasmic ribonucleoprotein granule), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0000932 (P-body), GO:0043232 (intracellular non-membrane-bounded organelle)
Protein: RNA-binding protein Musashi homolog 2 isoform X4 (A0A8M2B3X1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR000504: RNA recognition motif domain (domain) [21-187]
- IPR034126: RNA-binding protein Musashi homologue, RNA recognition motif 2 (domain) [111-184]
- IPR035979: RNA-binding domain superfamily (homologous_superfamily) [20-230]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [21-197]
Sequence:
MEGDGSQATSGSPNDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADAASVDKVLAQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLSYPNIVATYGRGYTGFAPSYSYQFPGFPDYGFYSSPSDQRGPPFSFADYGSLGPQAAQLLQSEHATSACNSPLQHLASPDQYKSPGTNPPRPGAFPGASSPGPVADLYGPTSQDSGVGNYISAASPQPGSGFGHSIAGPLIATAFTNGYH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0021537 (telencephalon development), GO:0060322 (head development), GO:0021988 (olfactory lobe development), GO:0030900 (forebrain development), GO:0021772 (olfactory bulb development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure), GO:1990904 (ribonucleoprotein complex), GO:0005844 (polysome)
Protein: Calymmin isoform X4 (A0A8M9QMD0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
Sequence:
MLRWTILRMMLLLWMTRVTLQGGTGYQPQKSNGNAAPISPGGYGSNNNAANLKGYGVYGGAQNKPANRGHLPHGYGNGNTNGNNGYKAPSYGGYSNLLGTHPRKGAGLGFGAGPAATKGQGSNPGGSSQYMGNTNGGTKGPKPGYGAQAGQTNGQIAKPNGYGGYPNGGAANQPKTGFSQYMGYPNGGTKGPKPGYGGYPNGGAAVQPGTGSSQYKGFPSGGIKGPNPGFAANAGASNEKGVKPNGYGGYPNGGAANQPNGGSSHYMGYPNGGTKGPKPGYGANAGPSAGQVAKPNGYGGYPNAGATNQPNGGPFQNMGYPNGGTKGPKPGYGAKAGPSAGHVAKPNGNGGYPNGGATSQHNGGSSQFMGYPNGGTKGPKSGYGANAGPSAGQVAKPNGNGRYPIGGVANQPNRGSSQNMGYPNGRTKGPKQGYGGYPNGGAANQPNGGSSQYMGYPNGGAKGPKAGYGAKSGPSSGQVSKPNGSSQYMGYPNGGTNGLKPGYGAKARTTYGQGAKPQNGFGGYSNGGAINQPNTGSSQYIGYPNGGFKGPLNGQGGRPYNGYGVPGYTSKGPKAANSGYMPVITGNKGASIGKGPKGEILSAEAPSQAPLSNTKGVLPVAQQEPVTGLLPNQGTKGLPVLQQTKGQILQASLPQSKTQNSMVPQFASNPFMQGPSSYKPSKMYKPPTSTIPIEKPEIPVIPQSVPAPESAFIPQTSQTTPLEQEQVLSLEQKSQVTAQPVTQQGSISSQAAQSTPVLQQAEIQSNPALPQLKNPTTTNPELTGLEQPNGQVQGAVPAKPDCGPEGRPNGQWVKLTNPGFGYPNGKGEGLSQPGFGAGIGGYPTQGMNNGHKAGYGGYGNQLKNHAGLQGGPPARLGTKGKSQTKYGIGGLPFGGSPSGYQSNPYGQYGNDGQRYGAKPYNPKAPGKYGYGSLPYNSQAFPESVARSPDFGGFPYNGQPLGYGSGKSTGKYGQKGPQYGGQSLGHGPDAISGKYGSPESLYTPETVNLGGNAKSTKYGNPAVSYELLGPVTDGQSVEENRSIETLHQGPEIDGQKAVDNFGDGEIPPHPDVPGAGEANAQSTEKYGTEDYNAGKPQPEAVSFPAVPTVGPAVTSLDTTLSLDGSSPVPVSVPDAVHEVPVSPILPQPDLPTLMLQPAPPQQIQIQQHLKLHFQPHSNSQTGKEGKYKLSGFFGNKYQG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0005201 (extracellular matrix structural constituent)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048731 (system development), GO:0001501 (skeletal system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062023 (collagen-containing extracellular matrix)
Protein: Stress-activated protein kinase JNK (A0A8M2B8C2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Responds to activation by environmental stress and pro- inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity
Subcellular location: Cytoplasm
InterPro domains:
- IPR003527: Mitogen-activated protein (MAP) kinase, conserved site (conserved_site) [102-204]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [188-200]
- IPR000719: Protein kinase domain (domain) [67-362]
- IPR050117: Mitogen-activated protein (MAP) kinase (family) [65-387]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [55-398]
- IPR008351: Mitogen-activated protein (MAP) kinase, JNK (family) [117-376]
Sequence:
MVFMNRRFLYNCSAPVLDVKIAFCQGFGKQVDVSYIAQHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAGYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDMWSVGCIFGEVIRGTVLFPGTDHIDQWNKVIEQLGTPSPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDCLFPADSEHNKLKASQARDLLSKMLIIDPAKRISVDEALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHSIDEWKELIYKEVMNFEERTKNGVVKGQPSPSGAAVNSSESLPPSSSVNDISSMSTDQTLASDTDSSLETSAGPLGCCR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity), GO:0004707 (MAP kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048732 (gland development), GO:0048483 (autonomic nervous system development), GO:0007399 (nervous system development), GO:0061008 (hepaticobiliary system development), GO:0048484 (enteric nervous system development), GO:0001889 (liver development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Lamin-B receptor isoform X1 (A0A8M9PP65)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm. Membrane; Multi-pass membrane protein. Nucleus
InterPro domains:
- IPR019023: Lamin-B receptor of TUDOR domain (domain) [1-56]
- IPR001171: Sterol biosynthesis ERG24/DHCR-like (family) [204-619]
- IPR018083: Sterol reductase, conserved site (conserved_site) [366-606]
Sequence:
MPPARFQIGDTVMGRWPGSNLYYEVKVMSFDNKTRLYTVIYKDGTELELKESDITSVVIFQTAGRSRSRSRSPGRSPGRSSARSPGRPRRSRSRSPARTPRRASSRSTEVRKEKLKEVLEVRLTPVAMKHENNSSNSKSEKKEENNTAKAAPVVTEEKTETESENQTGGRYNLRRRKDQGDGKAVELEKAVESEPLLQTKAPAAVKTADLEFGGRVGVLFLMFLLPVAVLVLLILCGQKDASLQSFPLELPALQSVWDCQVFGIVLLWLLFQAFLSLLPVGKLVEGMPLKNGKTLKYRINGFYALLLTAVAAGVAVYQEVDLSYIHAHFLQFYTSALLIATLLSIYLFIRSRWASKDELAPGGNSGYIIYDFFMGRELNPRIKSFDIKFFCEMRPGLMGWVLINFAMLLAEMKQQNLENPSPAMLLVNIFQLLWVIDGLWHEEKLLTMMDIMYDGFGFMLTFGDLAFVPFTFTCQAYYLVNHPNELSVFWIITLIAMNGVGYYIFRKANSQKFAFRKNPSDPAVSHLKTIPTATGKSLIVSGLWGFVRHPNYLGDIIMALAWSLPCGFNNLVPYFYLIYLVTLLVHRNARDERQCRKKYGSAWEEYCKAVPYRIFPRVY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016627 (oxidoreductase activity, acting on the CH-CH group of donors), GO:0016628 (oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0009790 (embryo development), GO:0016477 (cell migration), GO:0048598 (embryonic morphogenesis), GO:0007369 (gastrulation), GO:0001667 (ameboidal-type cell migration), GO:0042074 (cell migration involved in gastrulation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005635 (nuclear envelope), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031965 (nuclear membrane), GO:0019866 (organelle inner membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0005637 (nuclear inner membrane), GO:0005634 (nucleus)
Protein: ubiquitinyl hydrolase 1 (A0A8M2B591)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm. Nucleus
InterPro domains:
- IPR002653: Zinc finger, A20-type (domain) [877-912]
- IPR051346: OTU Domain-Containing Deubiquitinase (family) [83-684]
- IPR003323: OTU domain (domain) [177-357]
Sequence:
MTLDMDAVLSDFVRSTGAEPGLARDLLEGKNWDLSAALSDFEQLRQVHAGSLSCSFVEESEYPSIEKEMARTGRPLLHRQDEAVQAATEKRLSRGISHASSTIVSLARSHVSSTGGTNEQLLDTPLCTFQLPDLTVYRDDFRGFIERDLIEQSMMVALEQAGRLNWWTRLGTGCQSLLPLATSGDGNCLLHAASLGMWGFHDRDLMLRKSLYALMDHGQEREALKRRWRWQQTMQNKESGLVYTEEEWQKEWNELLKLASSEPRIHYSTNGSSGAESQEEPVYESLEEFHVFVLAHVLRRPIVVVADTMLRDSGGEAFAPIPFGGIYLPLEVPANKCHRSPLVLAYDQAHFSALVSMEQKDSSKEQVVIPLTDSDHKMLPLHFAVDPGADWEWGKDDNDNVMLASVTLSLEAKLHLLHCYMTVTWLPLPCEVQQAPLAQPESPTASAGEDARTPPDSGESDKESVSSSSNGNGDSSTTGTSGTTGKTSGGSSSSSSSSSNSSGGTTGTIGKEKGKKDKEKDKDKDKKRADSVANKLGSFGKSLGSKLKKNVGGLMPGKNASGTGGKQEGQEKKKGSLRGRKGSKDSSPSIQTGSEDSGKGSPSSTSERQNGGYSSESDPFKYSSDVKVSLSILRSAMQGERKYIFSALLTTSNRQPFQEEMIQRYLVDAEERFHAEQEQRREAERKAAGGLASTTGPQMKKDGPELSYRGFESKEEVTDSSPPNFNALKSSSFSPVMYSGVVPIPRHTFIDHSPSPMTQHLHMHHGYMDTRRQLAGGSPSSYPGLPSYATLPRHCPLAQGPPHAQYHPPSASLGSPSRIITPCLTSFPQEHDPTDYPSEPSGAYTNGLRDLRSTLDSRNGPMPVRHYSLGSAGGLANLQSSKCRTPTCNYYGHPETGNYCSYCYREELKRRETEPAIHRF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008234 (cysteine-type peptidase activity), GO:0019783 (ubiquitin-like protein peptidase activity), GO:0101005 (deubiquitinase activity), GO:0004843 (cysteine-type deubiquitinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007166 (cell surface receptor signaling pathway), GO:0007219 (Notch signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)