Protein: Cyclin-dependent kinase inhibitor 1B (O35792)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm. Endosome. Nucleus
InterPro domains:
- IPR003175: Cyclin-dependent kinase inhibitor domain (domain) [31-79]
- IPR044898: Cyclin-dependent kinase inhibitor domain superfamily (homologous_superfamily) [23-106]
Sequence:
MSNVRVSNGSPSLERMDARQTEHPKPSACRNLFGPVNHEELTRDLEKHCRDMEEASQRKWNFDFQNHKPLEGRYEWQEVERGSLPEFYYRPPRPPKSACKVPAQESLDVSGSRQAVPSIGSQANSEDRHLVDQMPDSSDSPAGLAEQCPGMRKRPAAEDSSSQNKRASRTEENVSDGSPNAGTVEQTPKKPGLRRQT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0031072 (heat shock protein binding), GO:0051087 (chaperone binding), GO:0030544 (Hsp70 protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0009628 (response to abiotic stimulus), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0009892 (negative regulation of metabolic process), GO:0048522 (positive regulation of cellular process), GO:0009719 (response to endogenous stimulus), GO:0008219 (cell death), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0051716 (cellular response to stimulus), GO:0065009 (regulation of molecular function), GO:0006950 (response to stress), GO:0048523 (negative regulation of cellular process), GO:0001101 (response to acid chemical), GO:0001666 (response to hypoxia), GO:0050790 (regulation of catalytic activity), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0044093 (positive regulation of molecular function), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0009410 (response to xenobiotic stimulus), GO:0044092 (negative regulation of molecular function), GO:0008285 (negative regulation of cell population proliferation), GO:0070482 (response to oxygen levels), GO:0060255 (regulation of macromolecule metabolic process), GO:1901700 (response to oxygen-containing compound), GO:0031324 (negative regulation of cellular metabolic process), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0045787 (positive regulation of cell cycle), GO:0051726 (regulation of cell cycle), GO:0010035 (response to inorganic substance), GO:0042127 (regulation of cell population proliferation), GO:1901698 (response to nitrogen compound), GO:0031325 (positive regulation of cellular metabolic process), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0045786 (negative regulation of cell cycle), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0071456 (cellular response to hypoxia), GO:0010038 (response to metal ion), GO:1901652 (response to peptide), GO:0043086 (negative regulation of catalytic activity), GO:0009743 (response to carbohydrate), GO:0043200 (response to amino acid), GO:0010562 (positive regulation of phosphorus metabolic process), GO:0032355 (response to estradiol), GO:0071453 (cellular response to oxygen levels), GO:0051246 (regulation of protein metabolic process), GO:0051248 (negative regulation of protein metabolic process), GO:0048662 (negative regulation of smooth muscle cell proliferation), GO:0048660 (regulation of smooth muscle cell proliferation), GO:0043434 (response to peptide hormone), GO:0010243 (response to organonitrogen compound), GO:1904029 (regulation of cyclin-dependent protein kinase activity), GO:0033993 (response to lipid), GO:0045737 (positive regulation of cyclin-dependent protein serine/threonine kinase activity), GO:0036293 (response to decreased oxygen levels), GO:0010563 (negative regulation of phosphorus metabolic process), GO:0051247 (positive regulation of protein metabolic process), GO:0014070 (response to organic cyclic compound), GO:0051338 (regulation of transferase activity), GO:0043085 (positive regulation of catalytic activity), GO:0051174 (regulation of phosphorus metabolic process), GO:0045736 (negative regulation of cyclin-dependent protein serine/threonine kinase activity), GO:0000079 (regulation of cyclin-dependent protein serine/threonine kinase activity), GO:0051347 (positive regulation of transferase activity), GO:1904705 (regulation of vascular associated smooth muscle cell proliferation), GO:0031399 (regulation of protein modification process), GO:1904030 (negative regulation of cyclin-dependent protein kinase activity), GO:0031400 (negative regulation of protein modification process), GO:0045937 (positive regulation of phosphate metabolic process), GO:1904706 (negative regulation of vascular associated smooth muscle cell proliferation), GO:1904031 (positive regulation of cyclin-dependent protein kinase activity), GO:0034284 (response to monosaccharide), GO:0019220 (regulation of phosphate metabolic process), GO:0043549 (regulation of kinase activity), GO:0036294 (cellular response to decreased oxygen levels), GO:0051348 (negative regulation of transferase activity), GO:0046686 (response to cadmium ion), GO:0031401 (positive regulation of protein modification process), GO:0045936 (negative regulation of phosphate metabolic process), GO:0042325 (regulation of phosphorylation), GO:0001933 (negative regulation of protein phosphorylation), GO:0001932 (regulation of protein phosphorylation), GO:0033674 (positive regulation of kinase activity), GO:0033673 (negative regulation of kinase activity), GO:0042326 (negative regulation of phosphorylation), GO:0045859 (regulation of protein kinase activity), GO:0042327 (positive regulation of phosphorylation), GO:0009746 (response to hexose), GO:0001934 (positive regulation of protein phosphorylation), GO:0071900 (regulation of protein serine/threonine kinase activity), GO:0009749 (response to glucose), GO:0045860 (positive regulation of protein kinase activity), GO:0006469 (negative regulation of protein kinase activity), GO:0071901 (negative regulation of protein serine/threonine kinase activity), GO:0071902 (positive regulation of protein serine/threonine kinase activity)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)