Protein: Serine/threonine-protein phosphatase (A0A7I2V4F7)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus, nucleolus. Nucleus, nucleoplasm
InterPro domains:
- IPR006186: Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase (domain) [35-305]
- IPR029052: Metallo-dependent phosphatase-like (homologous_superfamily) [15-313]
- IPR004843: Calcineurin-like, phosphoesterase domain (domain) [64-256]
- IPR031675: Serine-threonine protein phosphatase, N-terminal (domain) [24-61]
- IPR050341: Serine/threonine-protein phosphatase PP1 catalytic subunit (family) [29-310]
Sequence:
MGPPVSPTLLLSGSRVLTPHCAPVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0004721 (phosphoprotein phosphatase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0050839 (cell adhesion molecule binding), GO:0045296 (cadherin binding), GO:0004722 (protein serine/threonine phosphatase activity), GO:0042578 (phosphoric ester hydrolase activity), GO:0098631 (cell adhesion mediator activity), GO:0016791 (phosphatase activity), GO:0098632 (cell-cell adhesion mediator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0042752 (regulation of circadian rhythm), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0010646 (regulation of cell communication), GO:0019538 (protein metabolic process), GO:0009966 (regulation of signal transduction), GO:0043170 (macromolecule metabolic process), GO:0006793 (phosphorus metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0006796 (phosphate-containing compound metabolic process), GO:0030111 (regulation of Wnt signaling pathway), GO:0016311 (dephosphorylation), GO:0006470 (protein dephosphorylation), GO:0060828 (regulation of canonical Wnt signaling pathway), GO:0070262 (peptidyl-serine dephosphorylation), GO:0035970 (peptidyl-threonine dephosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005829 (cytosol), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)