Protein: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X2 (A0A8M2BKH8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR037858: ARAP, RhoGAP domain (domain) [1049-1227]
- IPR001849: Pleckstrin homology domain (domain) [435-1472]
- IPR000198: Rho GTPase-activating protein domain (domain) [1050-1236]
- IPR052227: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein (family) [5-1504]
- IPR013761: Sterile alpha motif/pointed domain superfamily (homologous_superfamily) [9-71]
- IPR001660: Sterile alpha motif domain (domain) [5-72]
- IPR029071: Ubiquitin-like domain superfamily (homologous_superfamily) [1263-1343]
- IPR008936: Rho GTPase activation protein (homologous_superfamily) [1048-1238]
- IPR001164: Arf GTPase activating protein (domain) [628-762]
- IPR000159: Ras-associating domain (domain) [1260-1354]
- IPR037278: ARFGAP/RecO-like zinc finger (homologous_superfamily) [638-755]
- IPR038508: ArfGAP domain superfamily (homologous_superfamily) [634-761]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [437-1474]
Sequence:
MHTMATIGPCSDAEDLLASIHLERYLDHFRQAGFLLARDFCHVDNAALNRVGVAATGHRKRILKLVEHIQLICQHQSKEPSLDRCNSESAIHDVTPVKAKPLSPSKPPGTTFQALRNSSAPNLCAQVKRSFSERSTSVVKPVPKPRTVFHKLRGDKFSLATQHEHRKSSQDPVVIDSSSLSSSTDTVKTATESKKGHLEPSLSCTALSPESEGPLPPVPPRLNRGIPPSTFRRMSGQERLSTPPLCTPPDSPSSYQCSPFTNTPGSPPSPPCSGLEMVSNEIYCGTLPDTPHVFWSRSVPVPPPRQEPSPSTENHSTLEKSNSSESSKRTSASAEEDDDMINPYCETVFHSKRQYQHSEVERSESKEKTSNKEDKLRDHGHHNHSWLKRLDSPGYCTVGESSHSFSLPHNLCSSEADEDIISPYASFTSLSERAAPILSGWLDKLSPQGNYVFQKRYVKFDGKNLMYFGSEKDAYPKGVIPLAAIQMARLAKDNKFEIVTSHRTFVFRADNDVQRSKWCSTLQERVKEQLVFGRPRFGPGSHCQKSGFLELKGTKSKIYTAIIMEQIWLYKSEQCFKNGIGITVIEARGATIRDGKGKSFDLITPYKTFSFTAETDREKRDWMEALQESIAETLSDYEVAEKIWSNRSNKICADCKAINPDWASINLCVVICKNCAGQHRGLGTMVSKVQSLKLDTSVWSNEIVQLFIMLGNDRANEFWAARLPVSEELDCDATPEQRREFISHKYKEGRYRHPHPSFSSQEELLKALCTAVTEQNLLKTVTQIFAEAEAARLADANGNDKRVSPHYSYTQSADSCVYDEIMQPILYSGFLYKSGSLNKGTLSRRTRDDFQKYWCSVEKSILFYESDRCHEPSMKIDVKDIICLGVSRPDSSNNSGFIDKFRYTFELYLMSDKLVQFGLETPDALHSWARAIGKATTPLSCHCLLAREFERVGVLRYKAMLDPQQWKEGFFVLQKSNLFICPGNDGAAEDIINLKRLQELSIASEMENHEKKDILVLVEKGRTLHLQGTGRTDFSLWYADIQKAAGGKGNTLKDQQLSRNDIPIIVDSCIAFITQYGLGHEGIYRKNGAKSRIKLLMEEFRKDARNVKLRIGDNFIEDVTDVLKRFFREIDDPIFMADLHPFWKEAAKIPLKTQRLDRYKELIRGLPRVNRTTLAALISHLYRVQKCADLNQMCTKNLSLLFAPSLFQTDGKGEHEVKIIEDLIDNYLYIFDVDEEHQTQIDLEISLITTWRDTQLSQAGDLIIEVYLEEKIPDCCITLKVSPTMCAEELTNQVLYMRNIPAGEKDVWMTFEAIEDGELERPLHPKEKVLEQALQWCKMADPSSAYLVVKKVPRGEAIDIFTAYKSEIVKSGVLKCREEPPKLLQGNKFQERSFQIKDHKLLLMKDKKSNKPEKEWQLKTLKIYMGIRKKLKPPTKWGLTVLLDKQQLYLSCSCETELWDWMTNLLKAQNDDLRPPVMRRHSSSDISKQKFGTMPLVPIRGEESNTNSTMLSANQTLRKLHTRRALSMFFPMKIQQQDSFEERIEIPEPLYEEVGDFGLQVLKSLETSFLSSGHAETQEVPMRPISLGQRKTTSLDRMLGSRPFVSSGESLDALSHDGSSDSLPIPGRHRAHRSCSPQQELLLQELSTMFCKKPESDEPESLT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0008289 (lipid binding), GO:0043168 (anion binding), GO:0005543 (phospholipid binding), GO:0035091 (phosphatidylinositol binding), GO:0005547 (phosphatidylinositol-3,4,5-trisphosphate binding), GO:1901981 (phosphatidylinositol phosphate binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0036303 (lymph vessel morphogenesis), GO:0001946 (lymphangiogenesis), GO:0001945 (lymph vessel development), GO:0048731 (system development), GO:0001944 (vasculature development), GO:0072359 (circulatory system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)