Protein: Serine peptidase inhibitor, Kunitz type 1 (F7ERY9)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [176-232]
- IPR002172: Low-density lipoprotein (LDL) receptor class A repeat (repeat) [312-349]
- IPR036880: Pancreatic trypsin inhibitor Kunitz domain superfamily (homologous_superfamily) [233-422]
- IPR036055: LDL receptor-like superfamily (homologous_superfamily) [311-351]
- IPR023415: Low-density lipoprotein (LDL) receptor class A, conserved site (conserved_site) [325-347]
- IPR011106: Seven cysteines, N-terminal (domain) [39-134]
- IPR020901: Proteinase inhibitor I2, Kunitz, conserved site (conserved_site) [272-415]
- IPR013980: MANSC domain (domain) [43-134]
- IPR002223: Pancreatic trypsin inhibitor Kunitz domain (domain) [241-420]
Sequence:
MAARRLAQASISTVCVWLLCALGLQGTETELPSAPPEFSGGAACLNRFTSGVPAFVLDTEASVSNGATFLGSPTVHRGWDCVRACCTTQNCNLALVELQPDGGEDAISACFLMNCLYEQNFVCKFAPKDGFINYLTQDLYNSYRELRTRGFGGSRIPRIWMGIDLKVQLQKPLVLRDADNTDWHLLQGDQDVSVKRNHPEEVELWGLKEGTYLFQLTRTDSDQLEETVNLTITVLTAEQTEDYCLASYKVGRCRGSFPRWYYDPKEQICKSFTFGGCLGNKNNYLREEECMLACKDVKGISPKRHHPVCTGSCHSTQFQCSNGCCIDGFLECDDTPDCPDGSDEATCEKYSSGFDELQSIHFLSDKGYCAELPDTGFCKENIPRWYYNPFSERCARFTYGGCYGNKNNFEKEQQCLESCRGISKKDVFGLRRESSVPSAGSVEVAIAVLLAVCIIVVLTILGYCFFKNQKKNFHSPLHQPPPTPASSTVSTTEDTEHLVYNHTTQPL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140678 (molecular function inhibitor activity), GO:0061134 (peptidase regulator activity), GO:0004857 (enzyme inhibitor activity), GO:0061135 (endopeptidase regulator activity), GO:0030414 (peptidase inhibitor activity), GO:0004866 (endopeptidase inhibitor activity), GO:0004867 (serine-type endopeptidase inhibitor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0050793 (regulation of developmental process), GO:0050794 (regulation of cellular process), GO:0051239 (regulation of multicellular organismal process), GO:0051094 (positive regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0051240 (positive regulation of multicellular organismal process), GO:0009719 (response to endogenous stimulus), GO:0048522 (positive regulation of cellular process), GO:0071495 (cellular response to endogenous stimulus), GO:0045597 (positive regulation of cell differentiation), GO:0045595 (regulation of cell differentiation), GO:2000026 (regulation of multicellular organismal development), GO:0042127 (regulation of cell population proliferation), GO:0051962 (positive regulation of nervous system development), GO:0008285 (negative regulation of cell population proliferation), GO:0070848 (response to growth factor), GO:0010720 (positive regulation of cell development), GO:0050769 (positive regulation of neurogenesis), GO:2000177 (regulation of neural precursor cell proliferation), GO:0051960 (regulation of nervous system development), GO:0045685 (regulation of glial cell differentiation), GO:0071772 (response to BMP), GO:2000178 (negative regulation of neural precursor cell proliferation), GO:0071363 (cellular response to growth factor stimulus), GO:0060284 (regulation of cell development), GO:0071773 (cellular response to BMP stimulus), GO:0014015 (positive regulation of gliogenesis), GO:0045687 (positive regulation of glial cell differentiation), GO:0050767 (regulation of neurogenesis), GO:0014013 (regulation of gliogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)