Protein: [histone H3]-trimethyl-L-lysine(4) demethylase (A6ICC6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR048615: Lysine-specific demethylase 5, C-terminal helical domain (domain) [606-660]
- IPR047981: Lysine-specific demethylase 5B, ARID domain (domain) [94-183]
- IPR047978: Lysine-specific demethylase 5B, first PHD-finger (domain) [311-356]
- IPR004198: Zinc finger, C5HC2-type (domain) [692-744]
- IPR019786: Zinc finger, PHD-type, conserved site (conserved_site) [312-1221]
- IPR036431: ARID DNA-binding domain superfamily (homologous_superfamily) [77-193]
- IPR013637: Lysine-specific demethylase-like domain (domain) [757-1088]
- IPR047979: Lysine-specific demethylase 5B, third PHD-finger (domain) [1486-1535]
- IPR001606: ARID DNA-binding domain (domain) [97-188]
- IPR019787: Zinc finger, PHD-finger (domain) [309-1538]
- IPR001965: Zinc finger, PHD-type (domain) [311-1536]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [288-1544]
- IPR003347: JmjC domain (domain) [453-619]
- IPR003349: JmjN domain (domain) [31-73]
- IPR011011: Zinc finger, FYVE/PHD-type (homologous_superfamily) [308-1540]
Sequence:
MEPATALPPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQLNKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSGDSLRCLQKPNLTSDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEEATEARTHNLRRRMGCATPKRENEKEVKSTIKQEPTEKKDCVLESEKDKPKSRAKKTATAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLLPPLHDVPKGDWRCPKCLAQECSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSGFPVRDGKIKISPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIEDEKALRETVRKLGVIDSERMDFELLPDDERQCIKCKTTCFMSAISCSCKPGLLVCLHHVKELCSCPPYKYNLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFKALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQSQLTVNELRQFVTQLCALPCVLSQTPLLKDLLNRVEDFQQQSQRLLSEERPRASELQQLLDVSFTFDVELPQLAEMRIRLEQARWLEEVQQACLDSSSLSLDDMRRLIDLGVGLAPYSAVEKAMARLQELLTVSEHWDDKAKSLLRARPRHSLSSLATAVKEMEEIPAYLPNGTVLKDSVQKARDWVQDVDALQAGGRVPVLETLIELVARGRSIPVHLNSLPRLEMLVSEVHAWKESAAKTFLLENSPYSLLEVLCPRCDIGLLGLKRKQRKLKDPLPSGKKRSTKLESLSDLERALTESKETASAMATLGEARLREMEALQSLRFANEEKLLSPAQDVETKVCLCQKTPATPMIQCELCRDAFHTSCVAVSSISQSSRIWLCPHCRRSEKPPLEKILPLLASLQRIRVRLPEGDALRYMIERTVNWQHRAQQLLSSGNLKLVQDQAGSGLLFSRWPASAGTASAADKVSQPPGTTSFSLPEDWDNRTSYLHSPFSTGQSCIPLHGLSPEVNELLMEAQLLQVSLPEVQELYQTLLTKPSSAQQADRSSPVRPSSEKNDCLRGKRDAINSLERKLKRRPEREGLPSERWDRVKKMRTPQKKKIKLSHPKDMNNFKLERERSYDLVRNAETHSLPSDTSYSEQEDSEDEDAICPAVSCLQPEGDEVDWVQCDGSCNQWFHQVCVGVSPEMAEKEDYICVRCTGKDAPSRK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0071495 (cellular response to endogenous stimulus), GO:0070848 (response to growth factor), GO:0002088 (lens development in camera-type eye), GO:0009888 (tissue development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0046677 (response to antibiotic), GO:0048513 (animal organ development), GO:0009636 (response to toxic substance), GO:0071774 (response to fibroblast growth factor), GO:0060992 (response to fungicide), GO:0030855 (epithelial cell differentiation), GO:0070306 (lens fiber cell differentiation), GO:0060429 (epithelium development), GO:0048880 (sensory system development), GO:0071363 (cellular response to growth factor stimulus), GO:0007423 (sensory organ development), GO:0044344 (cellular response to fibroblast growth factor stimulus), GO:0001654 (eye development), GO:0150063 (visual system development), GO:0043010 (camera-type eye development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)