Protein: Potassium voltage-gated channel subfamily H member 1 isoform X1 (A0A8M3ARE9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
- IPR018490: Cyclic nucleotide-binding domain superfamily (homologous_superfamily) [497-684]
- IPR001610: PAC motif (repeat) [101-143]
- IPR014710: RmlC-like jelly roll fold (homologous_superfamily) [537-713]
- IPR005821: Ion transport domain (domain) [226-498]
- IPR000014: PAS domain (domain) [46-145]
- IPR050818: Potassium channel, voltage-dependent, EAG/ELK/ERG-like, animal-type (family) [34-932]
- IPR000595: Cyclic nucleotide-binding domain (domain) [570-688]
- IPR000700: PAS-associated, C-terminal (domain) [100-152]
- IPR003949: Potassium channel, voltage-dependent, EAG (family) [17-734]
- IPR035965: PAS domain superfamily (homologous_superfamily) [46-142]
- IPR003938: Potassium channel, voltage-dependent, EAG/ELK/ERG-like (family) [219-658]
Sequence:
MAGGRRGLVAPQNTFLENIVRRSNVWTLSHRHTDTNFVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKSSTCSFMYGELTDKDTSEKVRLTFENYEMNSFEILMYKKNRTPVWFFVKIAPIRNEQEKVVLFLCTFSDITAFKQPIEDDSSKGWGKFARLTRALTSSRGVLQQLQPTVHKGENVHKHSRLAEVLQLGSDILPQYKQETPKTPPHIILHYCAFKTTWDWVILILTFYTAIMVPYNVSFKTKQNNVTWLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVINAFENVDENWNHRAVTQGISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWLACIWYSIGDYEVIDEDRNTVRTDSWLYMLAESIGTPYRFNASGTGRWEGGPTKDTVYITSLYFTMTSLTSIGFGNIAPTTDGEKIFAVAMMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIASTWSMSHGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTIHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDDEVVAILGKGDVFGDVFWKEVTLAQACANVRALTYCDLHVIKRDALQKVLEFYTAFSNHFSRNLLLTYNLRKRLVFRKISDVKREEEERLRRKNEAPLNLPPDHPVRRLFQRFRQQKEARLAAVRPNSEDSDLEKGQIHNEVISQDVIATTSIVTVTESPATPIPSHLIKNRTLGPFDQAKLSAPAPNASRMSEPRARGWARFRESVAKPESWGNVPKAESMETLPERSSSAKTSEPSGLKKTDSCDSGITKSDLRLDEGGIRTPVDRSPVQPDGKSPPIPPIPTIPEHTLQASLLELRTELKEELSALGNRMVALEAQVAEVLRLLRNRKSPTSPMSLFQISRPTSPDTDKEDMFP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0015079 (potassium ion transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0015267 (channel activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0005261 (monoatomic cation channel activity), GO:0022839 (monoatomic ion gated channel activity), GO:0005267 (potassium channel activity), GO:0022836 (gated channel activity), GO:0046873 (metal ion transmembrane transporter activity), GO:0022843 (voltage-gated monoatomic cation channel activity), GO:0005244 (voltage-gated monoatomic ion channel activity), GO:0005249 (voltage-gated potassium channel activity), GO:0022832 (voltage-gated channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0007389 (pattern specification process), GO:0030902 (hindbrain development), GO:0009790 (embryo development), GO:0021575 (hindbrain morphogenesis), GO:0001756 (somitogenesis), GO:0009888 (tissue development), GO:0003002 (regionalization), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0035282 (segmentation), GO:0007417 (central nervous system development), GO:0007399 (nervous system development), GO:0061053 (somite development), GO:0060429 (epithelium development), GO:0009952 (anterior/posterior pattern specification), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)