lokahq/bioreason-rl huggingface dataset:
Protein: Ganglioside-induced differentiation-associated protein 1 isoform X1 (A0A8M2B9N6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR004045: Glutathione S-transferase, N-terminal (domain) [1-37]
- IPR010987: Glutathione S-transferase, C-terminal-like (domain) [98-252]
- IPR036282: Glutathione S-transferase, C-terminal domain superfamily (homologous_superfamily) [135-233]
- IPR034336: Ganglioside-induced differentiation-associated protein 1, C-terminal domain (domain) [111-222]
- IPR036249: Thioredoxin-like superfamily (homologous_superfamily) [1-35]
Sequence:
MRLNPTGEVPVLVHDNHVICDPTQIMDYLEQNFCDEQTPKLIPEEGSTYYHRVQHYRELLDSLQMDAYTHGCILHPEITVDSHIPAYATTHIRTQIGNTESELKKLAVENPDLKDAYIAKQRRLKSKLFDHDNMKYLKKLLDELENVLDQVETELQRRSEETPEEGSQQAWLCGDFFSIADVSLAVTLHRLKFLGLSRRYWGNGMRVNLETYYERVLDRPTFRRVLGHVNNILISAVLPTAFRVAKKKAPAFVGATLLVGLIGGATYLAFIYFKKRLLVS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0016043 (cellular component organization), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0022008 (neurogenesis), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0120036 (plasma membrane bounded cell projection organization), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Solute carrier family 43 member 3 isoform X2 (A0A8M6YYI8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
- IPR011701: Major facilitator superfamily (family) [63-390]
- IPR027197: Equilibrative nucleobase transporter 1 (family) [13-419]
- IPR036259: MFS transporter superfamily (homologous_superfamily) [19-418]
Sequence:
MMAYKGSSGKVVRYKLTLATGLLECLCFAGVVFGWASLVFVLKTDGYFGDLCSNATDAGGEFSSDCGLQDEHFSLVFTVASFMNNFLTLPNGFLYDHFGTMATRLLAIFLYTTGTLIVAFSNKALSVLLFPALSFIAVGGILFLMTNMQVGNLFGSHRSTIITVYNGAFDSSSVIFLIIKVLYEKGVSLRSSFLFLSACNLIHLIRTLFLMPKSHIPYPIPQDYQYGISCAKSNSYNVEEYEAKREASSDRSRRAEEELLETDSIKLTDNPEKDSFRSCVLSWFFLWHLVWLSVMQLRHYFFIGTLNPMLNRLANQNPVTVSEYTNAFAFTQFCGVLCAPWNGLLMDRHKRKPLDPDVSEREADLRSSILSLLLTSLQCFLFSICASIPFLPLQYLTFILQVLNRSFLYGGNAAFISIA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0005342 (organic acid transmembrane transporter activity), GO:0008514 (organic anion transmembrane transporter activity), GO:0046943 (carboxylic acid transmembrane transporter activity), GO:0015171 (amino acid transmembrane transporter activity), GO:0015658 (branched-chain amino acid transmembrane transporter activity), GO:0015179 (L-amino acid transmembrane transporter activity), GO:0015175 (neutral L-amino acid transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0001654 (eye development), GO:0150063 (visual system development), GO:0043010 (camera-type eye development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Krueppel-like factor 5 (A0A8M9P800)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [360-428]
- IPR013087: Zinc finger C2H2-type (domain) [345-429]
Sequence:
MAATLLTMSAALAPGQDDFLSLLKPSLSDGFQQDSSLFCFEHKIPDSERGLSNDYSQAKLEMDKYLSPQPVVLPDLKKSRRESVSTMDQYFGDDHGSPYSINMNVYLPDIAYLRTGLCRAARHSVSNQVKTEPVTAPFSHPECPVSSSGPAPSALPDFTSIFNSNSTSGSGMDVVDDSAGVFVKQEMQGFDIPQDGPLFQLLNSELDVPDPTDPHAHSQMPTFHNLHLAAQQTAAKSYCGMAAHGYPLSHGHFVHPQDQAHSQLKMTYLPPSPPTSEPGSPDRQKELLHNLTPPPSYAATIASKMAGHAPSHPTPASTRPPTTTGSMPVRYNRRTNPDLEKRRIHHCDFPGCKKVYTKSSHLKAHLRTHTGEKPYRCTWEGCDWRFARSDELTRHFRKHTGAKPFQCAVCSRSFSRSDHLALHMKRHQN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0035295 (tube development), GO:0048731 (system development), GO:0055123 (digestive system development), GO:0048565 (digestive tract development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Actin filament-associated protein 1-like 2 isoform X3 (A0A8M9PX59)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR030113: Actin-filament associated protein (family) [1-885]
- IPR001849: Pleckstrin homology domain (domain) [206-472]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [183-474]
Sequence:
MDKHKVLEQLLEQLQKFLKILDVEKLSGNAKVQKGLLMELLQSYKSSNAGGDEEYIYMNKVIVTCQTQDKTNRDHRPEANGDPSKHISVKNPPEPPPPRPCNTGREPFPLPPAPAPASMENESYYEDPQPYDPISINDFGCFAVITGLRKRVEASNGVVYAVITREDTEQLSSSYESYDEEEVTKGKSTAQHQWPSPEASIELMKDARICAFLWRKKWLGQWAKQLCVVREHRLLCYKSSKDQTPLLDISLLGCSVVYKEKQTKRKEHKLKISPLGAEAIVLGLQSKEQAEQWLKVIQEISPKNTTGSDVTDSPTLICTKGEQSERYSVASESGSSTDSHAENMENKDVKKKYGKFSNLMNIGKKKVCSLESPEKSVDTSGYLNVLVNTQWRSRWCSVKDRQLWIYSDKSKGKVAQQPLSLEGCMVLPDPSPEHLYSFRIQMDGEELAILEAKSSADMGHWLGLILSQTGTKTDPEDLSYDYVNSERISSIVNAAKTSMYLMQRRYSEPNTYTDSPPSDPQTCDDIYDDVPSTENEQEEVQEVQNGSEEGTVNAEEENGKDRVYLDLIPLRSFLHTSSGRVSPQTSSTTQTEISPSTTPHVDDQLKEPVYESSLPTSTENEVPPPVAPRVDTDPSPVPNLHVQPQKISFLGQEIQKKASPLPKTQSLPQTSAQTPQSPPTSRARAASTDRLLDRLKFSPAGPGSVEVKLGKNRTEADVRRYTDDRDRLEREREEVKNTLATLRKDRREVKDELSSCQDPIRQASLEARLKQMEETCREAERRRVEVELSLMEVKENLRKVESGPFTLGTTVDSSLLDISVPKPAAVSSPAPNTPNNTNINTPACTNNEDSPVNSATALKNRPPSVMAASKGNVLQKAKEWEKKNTT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0060900 (embryonic camera-type eye formation), GO:0009887 (animal organ morphogenesis), GO:0048729 (tissue morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0009888 (tissue development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009790 (embryo development), GO:0048568 (embryonic organ development), GO:0048562 (embryonic organ morphogenesis), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0090596 (sensory organ morphogenesis), GO:0002072 (optic cup morphogenesis involved in camera-type eye development), GO:0002009 (morphogenesis of an epithelium), GO:0060429 (epithelium development), GO:0016331 (morphogenesis of embryonic epithelium), GO:0002011 (morphogenesis of an epithelial sheet), GO:0048592 (eye morphogenesis), GO:0001654 (eye development), GO:0048048 (embryonic eye morphogenesis), GO:0031076 (embryonic camera-type eye development), GO:0061386 (closure of optic fissure), GO:0150063 (visual system development), GO:0043010 (camera-type eye development), GO:0048593 (camera-type eye morphogenesis), GO:0048596 (embryonic camera-type eye morphogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Aspartate beta-hydroxylase domain-containing protein 2 (A0A8N7T6M3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR051821: Aspartyl/Asparaginyl beta-hydroxylase domain-containing protein (family) [23-351]
- IPR027443: Isopenicillin N synthase-like superfamily (homologous_superfamily) [155-348]
- IPR007803: Aspartyl/asparaginy/proline hydroxylase (domain) [181-336]
Sequence:
MSWSLDLVPLPPCSVLGGPPFSGLLWTVLLLFLWYCYRVGSDPPSHSGMLKSSSGRSSFSRSSSRSPVDPGLSSPKSSAAISLEAVEEEEGTESYLTPVLSHSPFPTDAAAGSRKLYRALQEYAKRYSWAGMGRIHKGLRNQARINDRPSIQKPHLFYLPDVPSIPFFPRDAHRHDIEVLEASYPIILAEFQAVYQKGIDTKLGWSYQGPKGQTVFPLYNAGVCVASNCRACPCSYRTLLSLRTFISSNSLGSAGFWLLGPGATLAGTYGPTNTRLRCHLGLQTPAQCELVVGGEPQCWSEGHCLLVDDSFLHTISHNGAAEDGPRVIFSVDLWHPNVAAAERQALDYIFAPEQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Interleukin 12a isoform X1 (A0A8M6Z2C4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR009079: Four-helical cytokine-like, core (homologous_superfamily) [50-208]
Sequence:
MCMCICVCVCVGIVISMALALALCSPVPPPDSQECVCSPAARSLLSALTHIMEKEGKMKEQDLFAGFNCTDLEAQMTPHTHTSSVCQPSVSANSSCSAHRSSNFSAVECVKNIRGDLRYYDLLLNSYKPSTQELSPVITANTQLINCLNQRCESAEGVFPQWRVWKGSSFDDRVSLCKTLKGFHIRSITVNRALAYIASGEHRK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (signaling receptor activator activity), GO:0048018 (receptor ligand activity), GO:0005125 (cytokine activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:1901700 (response to oxygen-containing compound), GO:0043207 (response to external biotic stimulus), GO:1901698 (response to nitrogen compound), GO:0010033 (response to organic substance), GO:0009617 (response to bacterium), GO:0043331 (response to dsRNA), GO:0002237 (response to molecule of bacterial origin), GO:0032496 (response to lipopolysaccharide), GO:0014070 (response to organic cyclic compound), GO:0033993 (response to lipid), GO:0043330 (response to exogenous dsRNA)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Rho guanine nucleotide exchange factor 9 (A0A8M9PZ81)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Acts as a guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters
InterPro domains:
- IPR035728: Rho guanine nucleotide exchange factor 9, SH3 domain (domain) [574-631]
- IPR000219: Dbl homology domain (domain) [703-887]
- IPR001849: Pleckstrin homology domain (domain) [918-1027]
- IPR001452: SH3 domain (domain) [575-634]
- IPR035899: Dbl homology (DH) domain superfamily (homologous_superfamily) [693-909]
- IPR055251: SOS1/NGEF-like, PH domain (domain) [913-1022]
- IPR036028: SH3-like domain superfamily (homologous_superfamily) [573-665]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [910-1064]
Sequence:
MRNSSTGSNRRKLFRPGSGPLHVNMLISGGSVVSAEAVWDHVTMAERELAFKAGDVIKVLDASNKDWWWGQIDDEEGWFPASFVRVDPHPPQPYTKPVFYINPIATPRFHNTTAKLWVNQENIATESAEGASEVQNGHTDPSNGCLCIGQPLQNRDQMRANVINEIMSTERHYIKHLKDICEGYLRQCRKRIDMFNDDQLKVIFGNIEDIYRFQMGFVRDLEKQYNIEEPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKLMKDGRYQHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQEHSDYRYVAAALAVMRNVTQQINERKRRLENIDKIAQWQASVLDWEGDDILDRSSELIYTGEMSWIYQPYGRSQQRVFFLFDHQLVLCKKDLIRRDILYYKGRIDMDRYAVRDAIDGRDDDFNVSVKNAFKLHNRDSDEIHIFLAKKPEEKIRWLRAFHEERKMVQEDEKIGFEISEYQKKQAAMTVRKVTKQKGEATKRYQV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0140678 (molecular function inhibitor activity), GO:0060589 (nucleoside-triphosphatase regulator activity), GO:0005085 (guanyl-nucleotide exchange factor activity), GO:0030695 (GTPase regulator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0016043 (cellular component organization), GO:0035239 (tube morphogenesis), GO:0044085 (cellular component biogenesis), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0030030 (cell projection organization), GO:0048514 (blood vessel morphogenesis), GO:0002040 (sprouting angiogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development), GO:0022607 (cellular component assembly), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0120031 (plasma membrane bounded cell projection assembly), GO:0046847 (filopodium assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: mitogen-activated protein kinase kinase (A0A8M9QMM1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [319-331]
- IPR017441: Protein kinase, ATP binding site (binding_site) [202-225]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [194-471]
- IPR000719: Protein kinase domain (domain) [196-469]
Sequence:
MRMCPALRMRTAAYREFWRTWQPPRLLQKLLSASEASITAGGWGAHRCSGRSSRVACASETVAENRAREGGLRRSTMAAPSSDSGSSCGGGGTAGPAGLSPRLGSIGAQDSNSCWRCQNETGFQINLSGVTQIKRKALKLNFANPPVKPAARLPITSTAPAFQNPHIERLRTHSIESSGKLKISPEQHCDFTAEDLKDLGEIGRGAYGSVNNMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMATSLDKFYKYVYCASDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRNGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPRWNSVFDQLTQVVKGEPPQLCSSEDRQFSHKFIQFVNLCLTKDESKRPKYRELLVRHTASVCKHPFILMYEERLVDVARYVCRILDQMPASPGSPMYVD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004712 (protein serine/threonine/tyrosine kinase activity), GO:0016301 (kinase activity), GO:0004708 (MAP kinase kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009888 (tissue development), GO:0009790 (embryo development), GO:0048598 (embryonic morphogenesis), GO:0048729 (tissue morphogenesis), GO:0060429 (epithelium development), GO:0007369 (gastrulation), GO:0060027 (convergent extension involved in gastrulation), GO:0002009 (morphogenesis of an epithelium), GO:0060026 (convergent extension)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Lysine (K)-specific demethylase 2B isoform X4 (A0A8M3AJC4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR041070: Jumonji, helical domain (domain) [248-290]
- IPR002857: Zinc finger, CXXC-type (domain) [444-490]
- IPR001810: F-box domain (domain) [977-1016]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [975-1238]
- IPR050690: JHDM1 Histone Demethylase (family) [1-1223]
- IPR019787: Zinc finger, PHD-finger (domain) [494-553]
- IPR001965: Zinc finger, PHD-type (domain) [499-551]
- IPR006553: Leucine-rich repeat, cysteine-containing subtype (repeat) [1008-1220]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [486-555]
- IPR003347: JmjC domain (domain) [92-260]
- IPR011011: Zinc finger, FYVE/PHD-type (homologous_superfamily) [497-554]
Sequence:
MEGKDFSYEYVQRHGLRDPIIFEKPEGLGIKMPDPDFTVNDVKLFVGSRRIVDVMDVATQKGTEMSMAQWRRYYETPPSQREKLYNVISLEFSHTKLETLVKRPSTVDMIDWVDNMWPRHLKERQRDSTNSIMEMQYPKVQKYCLMSVQGCYTDFHIDFGGTSVWYHIHKGCKVFWLIPPTPQNLELYENWVLSGKQGDIFLGDRATDCQRIELKQGYTFIIPSGWIHAVYTPVDTLVFGGNFLHSFNVPMQLDISGIEDRTRVPVKFRYPFFFEMCWYVLERYLYSLTNKSHLIPEFQKHSLGIGLKRENSEVLNGHAKEERDEMDAPSPPSAPGLKTHLTAFELEGLWRLVGKLESLPSNKKCVPSGIHNAAALLLDIRALLKEHANDIPKLSYTGRPIVRWPKRPPWYQPPPPPPPVMRPKLATTPIVPRPVKPASNMSVLRRRRVRCKRCEACLRTECGDCNFCRDMKKFGGPGKLKQTCVLRQCLAPGLPLSAVCELCGEGNQETSEELMECSNCAQIAHPSCLKTSGEGVVNKDLPSCWECPKCVLGKDTDSESSGSGDDITAQDGSGGRGGEGGAWHGVGRPPSSLSHGSLQKRAAAPEQRLRKRIKLDGGKSHKRKSSSLDPRVAKIYRRHGMEHDDDSGSDDDGDGGRMSSVRSSVSSSRRGYGASRRGVWRGSSQRGPRGGGSLSSSSLKMRRGLGARGERGGRVRLRGGSQMRRRRYETDDDDDDDDDDDDDDDDDDDEDEDDEDDSEEDRHVSRSEKEHRSRRRRRRGDDYDDDEDEDDDDEEDSEEQDYEGEDDEMEDLDDGGDEDDEDGENQSDSDPDPPVLLVSDLNDDLLNDSYLTVTLHRPPKAKRDPGSIVPKLEAAMSPRTGGSSGFMQRKTLPKARPKTSSSTPAGNGLSQAKSGRPTRRSSNQDGRERDTASPSSMSSRSSVSPPPPPPAVTSSSPSLLSHPSFRDAGNELGCEKDIWVSVFRYLDRTDLAVCMRVCKAWFKWCCDKRLWTRIDLSRCRALSPQAVTAIIKLQPVTLDLSWTPVSKKQLAWLIHHLPSLKDLIMSGCSSLCVSALSSPSCPSLRTLDLCWAVGVKDSQIKDLIVQPGSESRSRLRSLVSLRLSGLELSDAVIKTMVRHMPSLRQLDLSYCQGLTDQSINLLTATGCNTRNTLRQLNLSGCNKLSDGCLSYMKRLSALALLDLRGCKNVTRHGCENFISDLSYCTVFCLTEDKLIQRVS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0000003 (reproduction), GO:0032502 (developmental process), GO:0022414 (reproductive process), GO:0003006 (developmental process involved in reproduction), GO:0007530 (sex determination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000785 (chromatin), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome)
Protein: Lysophosphatidic acid receptor 2b isoform X2 (A0A8M9Q1Z5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell surface
InterPro domains:
- IPR017452: GPCR, rhodopsin-like, 7TM (domain) [45-289]
- IPR002277: Lysophosphatidic acid receptor EDG-2 (family) [19-303]
- IPR004065: Lysophosphatidic acid receptor (family) [3-310]
- IPR000276: G protein-coupled receptor, rhodopsin-like (family) [30-304]
Sequence:
MVCYNNETVVFFYSISHKNISDTWGTKAKAVVGMGLLVSVFVIFTNILVMAAIFMNRRFHYPIYYLLGNLAAADLFAGTSYMYLMFHTGPWTAKLTTYQWFVRQGLIDTSLTASVFNLMAIALERHQTIFTMQLHSKMTNHRVVLLILGIWTVAIIMGLVPAMGWNCMCDIGNCSTMAPLYSRSYLVFWAAINLLTFTVMVAVYTRIFIYVRRKSQRMSQHTSQVKHKETVVNLMKTVVMILGCFVVCWTPGMVLLLLDGLCHSCDVLTYEKFFLVLAESNSLMNPIIYSYRDKDMRDTFKRILCLCCRSKQSEEHSGVRFNTLEQEARRARDAGAQQENGGRLVLQENKEMLESSDS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0004930 (G protein-coupled receptor activity), GO:0045125 (bioactive lipid receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0032501 (multicellular organismal process), GO:0050793 (regulation of developmental process), GO:0002682 (regulation of immune system process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0051239 (regulation of multicellular organismal process), GO:0009653 (anatomical structure morphogenesis), GO:0051093 (negative regulation of developmental process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0048523 (negative regulation of cellular process), GO:0050794 (regulation of cellular process), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0045595 (regulation of cell differentiation), GO:1903706 (regulation of hemopoiesis), GO:2000026 (regulation of multicellular organismal development), GO:0001568 (blood vessel development), GO:0045596 (negative regulation of cell differentiation), GO:0048731 (system development), GO:0035239 (tube morphogenesis), GO:0045637 (regulation of myeloid cell differentiation), GO:0045638 (negative regulation of myeloid cell differentiation), GO:0048514 (blood vessel morphogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development), GO:0060284 (regulation of cell development), GO:0045646 (regulation of erythrocyte differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)