Protein: Metalloendopeptidase (A6HTK6)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR024079: Metallopeptidase, catalytic domain superfamily (homologous_superfamily) [125-321]
- IPR000152: EGF-type aspartate/asparagine hydroxylation site (ptm) [567-578]
- IPR000742: EGF-like domain (domain) [551-747]
- IPR049883: NOTCH1 EGF-like calcium-binding domain (domain) [707-746]
- IPR034036: Tolloid/BMP1 peptidase domain (domain) [125-324]
- IPR015446: Bone morphogenetic protein 1/tolloid-like protein (family) [29-982]
- IPR001506: Peptidase M12A (domain) [125-324]
- IPR018097: EGF-like calcium-binding, conserved site (conserved_site) [551-731]
- IPR035914: Spermadhesin, CUB domain superfamily (homologous_superfamily) [322-988]
- IPR000859: CUB domain (domain) [326-980]
- IPR001881: EGF-like calcium-binding domain (domain) [551-747]
- IPR006026: Peptidase, metallopeptidase (domain) [130-272]
Sequence:
MPGVARPPLPLLSLPLLLLLLLPRAGRPLDLADYTYDLGEEDAPELLNYKDPCKAAAFLGDIALDEEDLRAFRVQQAAVLRQQTAQRSSIKAAGNSSALGRQSTSGQPQRGSRGRWRSRPRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPSIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKKDNGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSNLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCEHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFVEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHSTECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTISKKGFHLRYTSTKFQDTLHSRK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0008233 (peptidase activity), GO:0005102 (signaling receptor binding), GO:0004175 (endopeptidase activity), GO:0008237 (metallopeptidase activity), GO:0004222 (metalloendopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0050793 (regulation of developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0051240 (positive regulation of multicellular organismal process), GO:0006807 (nitrogen compound metabolic process), GO:0098743 (cell aggregation), GO:0071840 (cellular component organization or biogenesis), GO:0051239 (regulation of multicellular organismal process), GO:0071704 (organic substance metabolic process), GO:0051094 (positive regulation of developmental process), GO:0044238 (primary metabolic process), GO:0009887 (animal organ morphogenesis), GO:2000026 (regulation of multicellular organismal development), GO:1901564 (organonitrogen compound metabolic process), GO:0001502 (cartilage condensation), GO:0009888 (tissue development), GO:0048731 (system development), GO:0019538 (protein metabolic process), GO:0048513 (animal organ development), GO:0016043 (cellular component organization), GO:0061036 (positive regulation of cartilage development), GO:0043170 (macromolecule metabolic process), GO:0051216 (cartilage development), GO:0048705 (skeletal system morphogenesis), GO:0061035 (regulation of cartilage development), GO:0006508 (proteolysis), GO:0001501 (skeletal system development), GO:0043062 (extracellular structure organization), GO:0061448 (connective tissue development), GO:0045229 (external encapsulating structure organization), GO:0097435 (supramolecular fiber organization), GO:0030198 (extracellular matrix organization), GO:0030199 (collagen fibril organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0005576 (extracellular region), GO:0005615 (extracellular space), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle)