Protein: Neuroepithelial cell-transforming gene 1 protein isoform X1 (A0A8M9Q5V8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm
InterPro domains:
- IPR000219: Dbl homology domain (domain) [173-355]
- IPR001849: Pleckstrin homology domain (domain) [385-502]
- IPR035899: Dbl homology (DH) domain superfamily (homologous_superfamily) [155-370]
- IPR055251: SOS1/NGEF-like, PH domain (domain) [381-497]
- IPR051480: Endocytic & GEF Adapter (family) [63-574]
- IPR001331: Guanine-nucleotide dissociation stimulator, CDC24, conserved site (conserved_site) [303-328]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [371-504]
Sequence:
MEETDGSPAPMAEPVNERPKRSKRKSSMVEADGSPERTFKRPSLRRGSSFTFLTPGPQWDFTLKRKRREKDDADAVSLCSFDFKEPCTKRVRPLGRVTSLANLISPVKNGAVRRFGQTLQASFRGDGRSPGVPQQKPCSKAAAPTPPKRRNSTLWSETLDVHQKGTFSTKEIKRQEAIFELSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTAIFGDLDAYIPLHEDLLDQLAKATGTDGTVRQIGKIVVDWLPRLNAYRAYCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILRHTPPDHPDKGSLEQAISVIQAVLADINMKKGESECQYYIDKLEYLEDKQKDPRIEQCKSLLCHGELRNKSGTKLHVFLFTEVLILTRPVTRNDRHCFQVYRQPIPVQDLVLEDLQDGDVRMGGSFRGAFSNADKAKNIFRVRFQDASQGQSHTLQVNDVFHKQQWLNCLRNAMSTQKDLTLSENEPLTTPATDVCAKRRSSSVSTVIQMDEMDENCPRAAASAPSSPSSEEPPSPTPSATSTLSSSSSSSSISAPIPSRKSKKDKRSLCPLGKRKETMV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0003712 (transcription coregulator activity), GO:0005515 (protein binding), GO:0140678 (molecular function inhibitor activity), GO:0005085 (guanyl-nucleotide exchange factor activity), GO:0060589 (nucleoside-triphosphatase regulator activity), GO:0019207 (kinase regulator activity), GO:0003713 (transcription coactivator activity), GO:0008047 (enzyme activator activity), GO:0030695 (GTPase regulator activity), GO:0019209 (kinase activator activity), GO:0019887 (protein kinase regulator activity), GO:0030295 (protein kinase activator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0007267 (cell-cell signaling), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0007389 (pattern specification process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0009798 (axis specification), GO:0198738 (cell-cell signaling by wnt), GO:0003002 (regionalization), GO:0010646 (regulation of cell communication), GO:0009888 (tissue development), GO:0009966 (regulation of signal transduction), GO:1905114 (cell surface receptor signaling pathway involved in cell-cell signaling), GO:0007166 (cell surface receptor signaling pathway), GO:0048382 (mesendoderm development), GO:0007492 (endoderm development), GO:0007167 (enzyme-linked receptor protein signaling pathway), GO:0016055 (Wnt signaling pathway), GO:0090092 (regulation of transmembrane receptor protein serine/threonine kinase signaling pathway), GO:0009953 (dorsal/ventral pattern formation), GO:0009950 (dorsal/ventral axis specification), GO:0007498 (mesoderm development), GO:0032925 (regulation of activin receptor signaling pathway), GO:0060070 (canonical Wnt signaling pathway), GO:0007178 (transmembrane receptor protein serine/threonine kinase signaling pathway), GO:1900107 (regulation of nodal signaling pathway), GO:0032924 (activin receptor signaling pathway), GO:0038092 (nodal signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)