Protein: Similar to golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (Predicted) (A6JHL5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Golgi apparatus, trans-Golgi network
InterPro domains:
- IPR032691: Mon2/Sec7/BIG1-like, HUS domain (domain) [402-551]
- IPR056604: GBF1-like, tetratricopeptide repeats domain (domain) [1490-1656]
- IPR035999: Sec7 domain superfamily (homologous_superfamily) [690-887]
- IPR023394: Sec7, C-terminal domain superfamily (homologous_superfamily) [774-898]
- IPR016024: Armadillo-type fold (homologous_superfamily) [58-1166]
- IPR000904: Sec7 domain (domain) [692-884]
Sequence:
MVDKNIYIIQGEINIVVGAIKRNARWSTHIPLDEERDPLLHSFSHLKEVLNSGTELSEIEPNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSCALIDPTHEGTAEGMENMADAVTHARFVGTDPASDEVVLMKILQVLRTLLLTPVGTHLTNESVCEIMQSCFRICFEMRLSELLRKSAEHTLVDMVQLLFTRLPQFKEEPKSYVGTNLKKLKMRAGGMSDSSKWKKQKRSPRPPRHTTKVMPGSELPTPNGAALSSNLTGGMPFIEAPTSISSASSEAASTVVSPCTDSGLELSSQATSKEDLTDLEQAGSPREITTTEPGSTEIGVSDQLDPQEGAHVEKAQSASVESIPEVLEECTSPTDHSDSASVHDMDYVNPRGVRFTQSSQKEGTALVPYGLPCIRELFRFLISLTNPHDRHNSEVMIHMGLHLLTVALESAPVAQCQTLLGLIKDEMCRHLFQLLSVERLNLYAASLRVCFLLFESMREHLKFQLEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWRIPSFVTELYINYDCDYYCSNLFEDLTKLLSKNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNTLNQQEKKETARPGFEAVDGSPDTYKSERAASDGKATGVPSDAPGLHFSSGGWLSTEHGKPGCSDLEEAGDSGVDKKTTRKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNMDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIHRLLEVFTEHWRSCNGSPFANSDACFALAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVWSVLLHRGATPEGIFLRVPPGSYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPSVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQLLPKAMVEVEDFVDPNGKISLQREETPSNRGESTVLSFVSWLTLSGPEQSSVRGPSTENQEAKRVALDCIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAVVGLLRLAIRLLRREEISGQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPDALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKMHRSATDADMANSGWLVVGKDDIDNSKPAAGLSRPGPSPLVNQYSLTVGLDLGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGCKSQDKRGKSHKYDSKGNRFKKKPKEGSMLRRPRASSQHATRAGHSDEEEDEGVPASYHTVSLQVSQDVRMQALTYLQRALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRASTLLSKVFLQHLSPLLSLSTFAALWLTILDFMDKYMHAGSSDLLSEAVPESLKNMLLVMDTAEIFHSADARGGSPSALWEITWERIDCFLPHLRDELFKQTVIQDPEKPESTRAASSSSPGSPVASSPSKQSPAPEGPPPLAQPPLILQPLTSPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPIPTSEVN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0050793 (regulation of developmental process), GO:0051240 (positive regulation of multicellular organismal process), GO:0050794 (regulation of cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0051239 (regulation of multicellular organismal process), GO:0051094 (positive regulation of developmental process), GO:0048522 (positive regulation of cellular process), GO:0050773 (regulation of dendrite development), GO:0045597 (positive regulation of cell differentiation), GO:2000026 (regulation of multicellular organismal development), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0045595 (regulation of cell differentiation), GO:0016043 (cellular component organization), GO:0051130 (positive regulation of cellular component organization), GO:0051128 (regulation of cellular component organization), GO:0051962 (positive regulation of nervous system development), GO:0022604 (regulation of cell morphogenesis), GO:0031344 (regulation of cell projection organization), GO:0031346 (positive regulation of cell projection organization), GO:0010256 (endomembrane system organization), GO:0060284 (regulation of cell development), GO:0010720 (positive regulation of cell development), GO:0048814 (regulation of dendrite morphogenesis), GO:0050769 (positive regulation of neurogenesis), GO:0051960 (regulation of nervous system development), GO:0006996 (organelle organization), GO:0010770 (positive regulation of cell morphogenesis involved in differentiation), GO:0010769 (regulation of cell morphogenesis involved in differentiation), GO:0007030 (Golgi organization), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0050767 (regulation of neurogenesis), GO:0050775 (positive regulation of dendrite morphogenesis), GO:0010975 (regulation of neuron projection development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0031984 (organelle subcompartment), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0042579 (microbody), GO:0005739 (mitochondrion), GO:0043233 (organelle lumen), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098791 (Golgi apparatus subcompartment), GO:0005788 (endoplasmic reticulum lumen), GO:0043231 (intracellular membrane-bounded organelle), GO:0005777 (peroxisome), GO:0005795 (Golgi stack), GO:0070013 (intracellular organelle lumen), GO:0005801 (cis-Golgi network)