lokahq/bioreason-rl huggingface dataset:
Protein: receptor protein-tyrosine kinase (A0A8M1QKN2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein
InterPro domains:
- IPR050122: Receptor Tyrosine Kinase (family) [118-908]
- IPR008266: Tyrosine-protein kinase, active site (active_site) [767-779]
- IPR001245: Serine-threonine/tyrosine-protein kinase, catalytic domain (domain) [560-902]
- IPR000719: Protein kinase domain (domain) [560-907]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [119-299]
- IPR001824: Tyrosine-protein kinase, receptor class III, conserved site (conserved_site) [619-632]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [112-285]
- IPR007110: Immunoglobulin-like domain (domain) [121-293]
- IPR017441: Protein kinase, ATP binding site (binding_site) [566-594]
- IPR020635: Tyrosine-protein kinase, catalytic domain (domain) [560-903]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [524-901]
Sequence:
MHLGNKLLLVLLVLHWSSLKDGLTEAHPRCDTDGSTVRCTLEETDLMSSDPIKLDVTEGQVVEIYSACEQNSSNERKCLCYQRTNSSIHLLQCIEKLGNEKYSVICGNKTVTAVRATQRRPSVPVLKAILKAGSTNLAQLVCTSEGYPKPTLRWYGNSDDAAEGMTSSACKTESTLISYYSYLSKNPNQKCCASNALGEECTEVYHYDLNEKNKQKSQNIIYLKSGQSLLLRAARKHFKNPGIKWHFNNTVIKGITSLQFYDWTEHLFIESVNMAHSGLYLCTSDTETPRNCSTHVKVFEHDQIDILHLNENNSILAKNKTGFCFQSQVFSYPKARCYWITPNQTQIQCDETSQSNFTSTFKLCNTEPGQYQMKLETQEYSVMRNVSLCISDIPKITIRKNSSFTTCETESPLPVTVSWKTCPSLAKCDPEDWKEIAADQPEFTDSDQFCQKKIGFSRRHLKSEDHLIKCCITNVAGTGCSEKILLQTKSHTYYVICFLLIVILFMIIIALIIFIRVKKPKYQSQIQMIQMIGPNDNDYIYIDFREFKYDLKWEFPRENLELGNELGSGAFGMVVQATAYGISKPGVSVQVAVKMLKEKHQAVEKEALMSELKMLTHIGHHENIVNLLGACTGSGPIYLIFQFCCNGDLLNYLKSNRECFHKYLTDAFNKDRFRGLYHNFQQNRNSSEYVLSDNSQCLNVTPASKEQENENDALLSSSISSGSPAEEMLECEDEHQEEELHSLTYDDLLSFSFQVAKGMQFLSAKNCIHRDLAARNVLVTHGRQVKIADFGLARDIEHDSNYVVRGNVRLPVKWMAPESIFKGIYTMESDIWAYGILLWEIFSLGVTPYPGVTVNNTFYRMIESGYHLEQPYYAAESVYKVMCRCWALNPVDRPCFSKIVAFMEKELAALEERLYYNVGGYSHDEITYQNAPVMPEDTPIVTDTHGSGAVRTEPPV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0046983 (protein dimerization activity), GO:0046982 (protein heterodimerization activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0030097 (hemopoiesis), GO:0002521 (leukocyte differentiation), GO:0030099 (myeloid cell differentiation), GO:0061515 (myeloid cell development), GO:0002573 (myeloid leukocyte differentiation), GO:0030225 (macrophage differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Band 4.1-like protein 3 isoform X2 (A0A8M9PFY0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR018980: FERM, C-terminal PH-like domain (domain) [196-286]
- IPR030691: Band 4.1-like protein 3, FERM domain, F1 sub-domain (domain) [1-83]
- IPR019748: FERM central domain (domain) [84-192]
- IPR008379: Band 4.1, C-terminal (domain) [960-1065]
- IPR000798: Ezrin/radixin/moesin-like (family) [14-215]
- IPR007477: SAB domain (domain) [461-508]
- IPR000299: FERM domain (domain) [1-282]
- IPR019749: Band 4.1 domain (domain) [1-192]
- IPR029071: Ubiquitin-like domain superfamily (homologous_superfamily) [1-81]
- IPR014352: FERM/acyl-CoA-binding protein superfamily (homologous_superfamily) [79-186]
- IPR014847: FERM adjacent (domain) [288-334]
- IPR035963: FERM superfamily, second domain (homologous_superfamily) [83-187]
- IPR018979: FERM, N-terminal (domain) [5-67]
- IPR019747: FERM conserved site (conserved_site) [55-191]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [187-281]
Sequence:
MQCKITLLDGSDYTCVVEKRDKGQVLFDKVCEHLNLLEKDYFGITFRDVENQKNWLDPAKDMKKQIRGVAWNFSFNVKFYPPEPALLSEDITRYYLCLQLRDDISSGRLPCSFATHTVLGSYTVQSELGDHDPEECGSEYTSEFRFAPQQTKEMEEKIIDLHKNYKGMTPAEAEMHFLENVKKLSMYGVDLHHAKDSEGVEIMLGVCSSGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLVLPETPPKKFLTLGSKFRYSGRTQAQTRRASSQIVRPAPYFQRSSSKRYTMSRSLDGEMGTALYGAAKGIAMSDLITTVTPEKKVEEEPQPQKHTHADKQMQPQTETETETDTHTQTQTVLVENVMILEDDDETTRATELSLPSPATPARLDTRTDLTDTAVDGELTATESDQEDESEAKTKEADLTPDEQLKPQTNISELKRTFLEGGAEPAGLTEWEKRLSSSPLRSPRREEPPMIEPLELDEIKQEVVVETQEVAETQEVAAALDTQENNRKVDEESDGWVIINKVPPFEAHKAPVETRDKSSIQPEIIVQDASPPAEPMKEFPEDVPAEKMDPEKTTKDEAPPEKTTVEEALPEKTTVDEALPEKTTVDETPLEKTIEKTTVDETPPEKIHSEKTEDVPPKVPPKVPPKVPEKKHSSSYRFLSSMSSAPPPSSVRPRSEDLSAGRISPALLRTSPTAKVPKPSFEEMSPELTALLQSARSWTPVPASASPSASASALVTPAPAALHTPQNQPSESVDEHLGKGLTEEERPADEPLDKPQVPAPPAGPLEPDGYYQACVACVEPLSSVRALDESESDGDSSDSSSVNSTNLDGPLERVAPQRAESPSESESEGESFTLSTDDEDDDGDRSPNISLSEQRGVAEGHSGEVDLMAGVETGVLSFRSVSGDTHDTHETHDTPVIQTEIKTITYEALQAETDGDADPGVLMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVISGDADIDHDEALAQAIKEAKEQHPDMSVTKVVVHKETEITPEEAEE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005516 (calmodulin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0065008 (regulation of biological quality), GO:0050794 (regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0050803 (regulation of synapse structure or activity), GO:0044087 (regulation of cellular component biogenesis), GO:0050807 (regulation of synapse organization), GO:1901888 (regulation of cell junction assembly), GO:0051963 (regulation of synapse assembly), GO:1904889 (regulation of excitatory synapse assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0019898 (extrinsic component of membrane), GO:0005886 (plasma membrane), GO:0019897 (extrinsic component of plasma membrane)
Protein: Cytohesin-1 isoform X1 (A0A8M2BHC1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR001849: Pleckstrin homology domain (domain) [279-397]
- IPR035999: Sec7 domain superfamily (homologous_superfamily) [78-271]
- IPR023394: Sec7, C-terminal domain superfamily (homologous_superfamily) [155-278]
- IPR000904: Sec7 domain (domain) [74-263]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [279-406]
Sequence:
MGTVSELCASSFQAFLCPTVHPAPPAVPDDLTPEEKQELENIRRRKQELLEDIQRLKDEITKVTNEIECLGSTQERINMQRSKQMAMGRKKFNMDPKKGIQFLIENELLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNPGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPSAERFICMNRGINDGGDLPEDLLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELFIPDNKDQVIKACKTEADGRVVEGNHTFYRISAPTTEEKEDWIKSIKSAISRDPFYEMLAARKKKASSLKRQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009790 (embryo development), GO:0048729 (tissue morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0009888 (tissue development), GO:0007369 (gastrulation), GO:0002009 (morphogenesis of an epithelium), GO:0055113 (epiboly involved in gastrulation with mouth forming second), GO:0060429 (epithelium development), GO:0002011 (morphogenesis of an epithelial sheet), GO:0001702 (gastrulation with mouth forming second), GO:0090504 (epiboly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Bridging integrator 1b isoform X5 (A0A8M3AT31)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR004148: BAR domain (domain) [16-287]
- IPR001452: SH3 domain (domain) [472-543]
- IPR027267: AH/BAR domain superfamily (homologous_superfamily) [9-288]
- IPR003005: Amphiphysin (family) [1-542]
- IPR036028: SH3-like domain superfamily (homologous_superfamily) [468-542]
Sequence:
MAEVGKGVNAGKLASNVQKRLTRAQEKVMQKLGKADETKDTAFEEQVANFNKQMNEGTKLQKDLKAYLLAVKTMHECSKRLHDCLAEMYDPEWFGKEEVDSIAEEMIEKEMDNNLEDTDLLWQDFHEKLLDNAVISMDAYLAQFPDIKARIAKRERKLVDFDSARHHFASVQKGKKKDEAKIAKPLALVEKAAPVWAQGILTAHQIAQTNLTRNQAEEDLGRAQKVFEEINYDLQEELPTLWNSRVGLYVNTFRSVSGLEETFHRDMGKLNQNLSDIMTKLEEQRVAKKGVTTASTGKSDDAANHNQETSDAPKSPSKLRDVPPVSRPPRPASSQEVKPDKIINLFEDAEVSDSNTTTQPEQGASWNSWEPAQSPAVSPSQQWDSDNEADAQPHGQPYAAPEWDDDVTPAVQSYEPPSWDEQDGAPAQSGWDGQTAAPAQPDWEDEHWDEEGSQNEAPTVTNGSSDTELPPSVLFKVKTMHDYSATDSDELDLKAGDIVLVLPFANPDEADDGWLMGVKESHWLQNKNLLAKGVFPENFTQKL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0003008 (system process), GO:0003012 (muscle system process), GO:0003013 (circulatory system process), GO:0003015 (heart process), GO:0008015 (blood circulation), GO:0006936 (muscle contraction), GO:0006941 (striated muscle contraction), GO:0060047 (heart contraction), GO:0060048 (cardiac muscle contraction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0030017 (sarcomere), GO:0031674 (I band), GO:0030018 (Z disc), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043292 (contractile fiber), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0030016 (myofibril), GO:0043232 (intracellular non-membrane-bounded organelle)
Protein: Muscleblind-like protein 2 isoform X5 (A0A8M3BD13)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm. Nucleus
InterPro domains:
- IPR000571: Zinc finger, CCCH-type (domain) [13-238]
- IPR054429: Muscleblind-like, CCCH zinc finger (domain) [48-251]
Sequence:
MALNIASIRDTKWLTLEVCRQFQRGTCSRSDEECKFAHPPKSCQVENGRVIACFDSLKGRCTRENCKYLHPPAHLKTQLEINGRNNLIQQKTAAAMLAQQMQFMIPGTTMQPVPTFPVSQGLGSNPGLSYAPYLTPMSHGMGLVPTEMLPSTPVIVPGSPPVSVPSSSSTQKLLRTDKLEVCREFQRGNCARGETDCRFAHPSDSPMIDTSDNTVTVCMDYIKSRCSREKCKYFHPPAHLQAKIKAAQHQANQTAVAAQAAAAAMAFPHGVLQPLPKRPALEKSNGASTLFNPSVLHYQQALASAQLQQPTAAFFPTGSVLCMAPASSIDHLEVNHRRGTGCQEAALRNPKRSPCKYDLPSPLELQQPAC
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0001069 (regulatory region RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009790 (embryo development), GO:0061061 (muscle structure development), GO:0048513 (animal organ development), GO:0048731 (system development), GO:0007517 (muscle organ development), GO:0048880 (sensory system development), GO:0072359 (circulatory system development), GO:0007507 (heart development), GO:0009792 (embryo development ending in birth or egg hatching), GO:0007423 (sensory organ development), GO:0043009 (chordate embryonic development), GO:0150063 (visual system development), GO:0001654 (eye development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Ubiquitin carboxyl-terminal hydrolase 7 (A0A8M9Q474)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR018200: Ubiquitin specific protease, conserved site (conserved_site) [192-442]
- IPR001394: Peptidase C19, ubiquitin carboxyl-terminal hydrolase (domain) [191-502]
- IPR050164: Ubiquitin carboxyl-terminal hydrolases (family) [77-506]
- IPR024729: Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain (domain) [604-849]
- IPR028889: Ubiquitin specific protease UPS, catalytic domain (domain) [191-505]
- IPR029346: Ubiquitin carboxyl-terminal hydrolase, C-terminal (domain) [859-1070]
- IPR038765: Papain-like cysteine peptidase superfamily (homologous_superfamily) [186-534]
- IPR008974: TRAF-like (homologous_superfamily) [40-187]
- IPR002083: MATH/TRAF domain (domain) [45-172]
Sequence:
MDKPGDPDDPPRIPQNPVINGNVAMADGHNNTEEDMEDDTSWRSEATFPFVVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAMLKIINYKDDEKSFSRRISHLFFHKENDWGFSNFMSWSDVTDPERGFVEDDKVTFEVYVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRRAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKHVDYRSERIEDYYDIQLSIKGKKNIFESFKDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTFPPILHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKPDVKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKVSVTAPIWCKFDDDVVSRCTKEEATEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQPVTDMDIPQQLVERLQEEKRVEAQKRKERQEAHLYMQVQMVTEDQFCGHQGNDMYDEEKVKYTVFKVLKSSTLAEFVQNLSQTMGFPQDQMRLWPMQARSNGTKRPAMLDYEADCNKSMIDLSDNENPWTIFLETVDPEMAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCERAGFQQGTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDTSELPTAKDYFRDLYHRVDVIFCDKTIHNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKAIWLNSMFREEEITLYPDKHGCVRDLLEECKKAVELSDKGSEKLRLLEIVSYKIIGVHQEDELLECLSPAASRTFRIEEIPLDQVDLDKENEMLIPVAHFHKEVFGTFGIPFLLKIRQGEPFREVMKRIQSMLDIQEKEFEKFKFAIVMMGRHQYINEEDYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRGRYTYLEKAIKIHN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0008233 (peptidase activity), GO:0008234 (cysteine-type peptidase activity), GO:0019783 (ubiquitin-like protein peptidase activity), GO:0101005 (deubiquitinase activity), GO:0004843 (cysteine-type deubiquitinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0048856 (anatomical structure development), GO:1904888 (cranial skeletal system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: A-kinase anchor protein 10, mitochondrial isoform X3 (A0A8M3B9Z5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR037719: A-kinase anchor protein 10, PKA-binding (AKB) domain (domain) [598-636]
- IPR036305: RGS domain superfamily (homologous_superfamily) [91-488]
- IPR052246: Cell Polarization and PKA Anchoring (family) [1-632]
- IPR044926: RGS, subdomain 2 (homologous_superfamily) [72-486]
- IPR016137: RGS domain (domain) [104-484]
Sequence:
MSFFRRKAKGKEPERPADAKASKAPVSPHSPSLSGRNHHAILEAAGPSHVAISAISANMDSFARGRTAILKKQPSHMEAAHFGDLGRSSVNYQIQETRSRLSKTVDQILRDNVALPYFIQFMETRSAEHLVRFWLEAESFRSTSWSRVRAHSLNSVKHSTLAEPAAALGSPDSPDSPNHSSRPLNLDEGDEEDAFSSRTSSRPHTPSPQDTNSHSGALMSHRDSVSFDGTAQPGTLQLQPALRSETPTRQTSSRTGTPVKGLRELSDKLMKSIERDAVNIFTKYISPDAARPIPITEQIRNDIVAKICGEDGQVDPNCFVIAQSVVFSIIDQQHFTEFLRSHYFCKYQIEVLTSGSVFLADILFCESALFYFSEYMEKEDAMNVLQFWLAAENFQDQLAAKKGQYDGQEAQNDAMILYDKYFSLQATNPLGFGDSVRMEIESNICREGGPLPDCFNTPLRQAWTTMEKVYMPGFLSSNLYYKYLSDLINSVRVDEFIGGNANTPNQGWTQEGERNSSVTEGSHVQLQQGTKKAAIKILKNFDEAITVDIASLDPESLYQRPYAGRMTFGKVNELGQFIREAEPEPDVKKSKGSMFSLAMKKWVQGNSDEAQEEMAWKIAKMIVNDVMQQGHHGSPEL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0042592 (homeostatic process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0001775 (cell activation), GO:0045321 (leukocyte activation), GO:0048871 (multicellular organismal-level homeostasis), GO:0002262 (myeloid cell homeostasis), GO:0034101 (erythrocyte homeostasis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0046649 (lymphocyte activation), GO:0048872 (homeostasis of number of cells), GO:0030097 (hemopoiesis), GO:0002521 (leukocyte differentiation), GO:0030218 (erythrocyte differentiation), GO:0030099 (myeloid cell differentiation), GO:0030098 (lymphocyte differentiation), GO:0061515 (myeloid cell development), GO:0048821 (erythrocyte development), GO:1903131 (mononuclear cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: GTP-binding protein RAD isoform X2 (A0A8M9Q175)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR001806: Small GTPase (family) [45-268]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [48-224]
- IPR005225: Small GTP-binding domain (domain) [52-205]
- IPR017358: Ras-related small G protein, RGK family (family) [4-268]
- IPR051641: RGK GTP-binding regulators (family) [31-268]
Sequence:
MPVDDRELRSMPAAQPSELPGLMRFNADRNSCVSDSSDSVISSGSDSDGQVYKVVLLGEHGVGKSSLARIFGGVEDSNDCEETGNTYDRSLVVDDEETSILLYDIWEQDNSQWLQDQCMRMGDAYIIVYSVTDKSSFEKASELRIQLRRARQSENIPIILVGNKSDLVRSREVSMDEGSACAVVFDCKFIETSASLHHNVRDLFEGIVRQIRLRKDSKEENARRMANCKRRESISKKAKRFLGRMVARKNKKMAFRQKSKSCHDLSVL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0016247 (channel regulator activity), GO:0099106 (ion channel regulator activity), GO:0005246 (calcium channel regulator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0022008 (neurogenesis), GO:0030182 (neuron differentiation), GO:0007399 (nervous system development), GO:0071542 (dopaminergic neuron differentiation), GO:0048699 (generation of neurons)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Sodium/iodide cotransporter isoform X1 (A0A8M9Q9Q5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
Sequence:
MWASLFSTGLICTFYTTVGGMKAVIWTDVFQIVVMLSGFIAVFIQGTILAGGPARVLEIANNGSRINFNDFAIDPQRRYSFWSFTVGGTMVWLSMYGANQAQVQRYISCRTEKQAQLALLVNQVGLCLIVSSAATCGIVMFALYSNCDPLKIGRISAPDQYMPYLVLDIFRNHPGFPGLFLACAYSGTLSTVSTSINAMAAVTMEDVMKPWLITISQRKQLMLSRALSLFYGLGCITMAALSSLLDWGVLQGSFTVMGVVNGPLLGAFALGMFVPATNKPGVFSGVAVGFCLSLWLAVGSTIYPPSPQIMGVLPTSAGQCLTTNATLNTTASVLASSVPLDYSFQNIYSISYLYFGALSTSAVVLVGVVVSYITGPTKKDSISPGLLRWNLEQKPCDASCHILNETITLNPTEILLTPKELFPIAADKQDILLTKGEI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0008509 (monoatomic anion transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0015103 (inorganic anion transmembrane transporter activity), GO:0022853 (active monoatomic ion transmembrane transporter activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0015081 (sodium ion transmembrane transporter activity), GO:0015291 (secondary active transmembrane transporter activity), GO:0015296 (monoatomic anion:monoatomic cation symporter activity), GO:0015293 (symporter activity), GO:0015294 (solute:monoatomic cation symporter activity), GO:0046873 (metal ion transmembrane transporter activity), GO:0015370 (solute:sodium symporter activity), GO:0015373 (monoatomic anion:sodium symporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0006811 (monoatomic ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)