Protein: Gut-enriched kruppel-like factor (F7F8L9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [413-481]
- IPR013087: Zinc finger C2H2-type (domain) [399-482]
Sequence:
MRQPPGESDMAVSDALLPSFSTFASGPAGREKTLRPAGAPTNRWREELSHMKRLPPLPGRPYDLAATVATDLESGGAGAACSSNNPALPRRETEEFNDLLDLDFILSNSLSHQESVAATVTTSASASSSSSPASSGPASAPSTCSFSYPIRAGGDPGVAAGNTGGGLLYSRESAPPPTAPFNLADINDVSPSGGFVAELLRPELDPVYIPPQQPQPPGGGLMGKFVLKASLSTPGSEYTSPSVISVSKGSPDGSHPVVVAPYSGGPPRMCPKIKQEAVPSCTVSRSLEAHLSAGPQLSNGHRPNTHDFPLGRQLPTRTTPTLSPEELLNSRDCHPGLPLPPGFHPHPGPSYPPFLPDQMQSQVPSLHYQELMPPGSCLPEEPKPKRGRRSWPRKRTATHTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0030234 (enzyme regulator activity), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0097159 (organic cyclic compound binding), GO:0005515 (protein binding), GO:0008134 (transcription factor binding), GO:0003676 (nucleic acid binding), GO:0001216 (DNA-binding transcription activator activity), GO:0019899 (enzyme binding), GO:0019207 (kinase regulator activity), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific), GO:0001228 (DNA-binding transcription activator activity, RNA polymerase II-specific), GO:0035014 (phosphatidylinositol 3-kinase regulator activity), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003677 (DNA binding), GO:0001221 (transcription coregulator binding), GO:0042826 (histone deacetylase binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0023057 (negative regulation of signaling), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0051241 (negative regulation of multicellular organismal process), GO:0051239 (regulation of multicellular organismal process), GO:0009892 (negative regulation of metabolic process), GO:0048522 (positive regulation of cellular process), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0009893 (positive regulation of metabolic process), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0006950 (response to stress), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0006979 (response to oxidative stress), GO:0008285 (negative regulation of cell population proliferation), GO:0044057 (regulation of system process), GO:0009966 (regulation of signal transduction), GO:0071495 (cellular response to endogenous stimulus), GO:0060255 (regulation of macromolecule metabolic process), GO:1901700 (response to oxygen-containing compound), GO:0043502 (regulation of muscle adaptation), GO:0031324 (negative regulation of cellular metabolic process), GO:0010033 (response to organic substance), GO:0009891 (positive regulation of biosynthetic process), GO:0010035 (response to inorganic substance), GO:0042127 (regulation of cell population proliferation), GO:1901698 (response to nitrogen compound), GO:0010646 (regulation of cell communication), GO:0031325 (positive regulation of cellular metabolic process), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0080090 (regulation of primary metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0034599 (cellular response to oxidative stress), GO:0071417 (cellular response to organonitrogen compound), GO:1901652 (response to peptide), GO:0097305 (response to alcohol), GO:1901654 (response to ketone), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0071310 (cellular response to organic substance), GO:0062197 (cellular response to chemical stress), GO:1901699 (cellular response to nitrogen compound), GO:0090257 (regulation of muscle system process), GO:1902532 (negative regulation of intracellular signal transduction), GO:0048662 (negative regulation of smooth muscle cell proliferation), GO:0010468 (regulation of gene expression), GO:0048660 (regulation of smooth muscle cell proliferation), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0010243 (response to organonitrogen compound), GO:0033993 (response to lipid), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0051252 (regulation of RNA metabolic process), GO:0042542 (response to hydrogen peroxide), GO:0014070 (response to organic cyclic compound), GO:0051253 (negative regulation of RNA metabolic process), GO:1901701 (cellular response to oxygen-containing compound), GO:0000302 (response to reactive oxygen species), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:1902531 (regulation of intracellular signal transduction), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0032526 (response to retinoic acid), GO:1901655 (cellular response to ketone), GO:0043408 (regulation of MAPK cascade), GO:0014066 (regulation of phosphatidylinositol 3-kinase signaling), GO:0071300 (cellular response to retinoic acid), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0071407 (cellular response to organic cyclic compound), GO:0071396 (cellular response to lipid), GO:0046898 (response to cycloheximide), GO:0051898 (negative regulation of protein kinase B signaling), GO:0014067 (negative regulation of phosphatidylinositol 3-kinase signaling), GO:1901653 (cellular response to peptide), GO:0051896 (regulation of protein kinase B signaling), GO:1902680 (positive regulation of RNA biosynthetic process), GO:1902679 (negative regulation of RNA biosynthetic process), GO:0034614 (cellular response to reactive oxygen species), GO:0097306 (cellular response to alcohol), GO:0070301 (cellular response to hydrogen peroxide), GO:0043409 (negative regulation of MAPK cascade), GO:0006357 (regulation of transcription by RNA polymerase II), GO:0045893 (positive regulation of DNA-templated transcription), GO:0045892 (negative regulation of DNA-templated transcription), GO:0070373 (negative regulation of ERK1 and ERK2 cascade), GO:1903507 (negative regulation of nucleic acid-templated transcription), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0070372 (regulation of ERK1 and ERK2 cascade), GO:0045944 (positive regulation of transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000785 (chromatin), GO:0005667 (transcription regulator complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome), GO:0005634 (nucleus)