Protein: Insulin-like growth factor 2 receptor, isoform CRA_b (A6KJW4)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR000479: Cation-independent mannose-6-phosphate receptor repeat (repeat) [119-2270]
- IPR013806: Kringle-like fold (homologous_superfamily) [1886-1934]
- IPR000562: Fibronectin type II domain (domain) [1887-1935]
- IPR009011: Mannose-6-phosphate receptor binding domain superfamily (homologous_superfamily) [32-2275]
- IPR044865: MRH domain (domain) [42-2271]
- IPR036943: Fibronectin type II domain superfamily (homologous_superfamily) [1885-1935]
Sequence:
MRAVLPGPVPSGPRVALLLPLLLLLLVAAAGSAQAQAVDLDALCSYTWEAVDSKNNAVYKINPCGHVDNPRCGPTSAVCMCDLKSENCRSVGDSLLRSSAKSLLEFNTTTGCQPSEHRIQTSITFLCGKTLGTPEFVTATDCVHYFEWRTTAACKKDIFKADKEVPCYVFDDKLQKHDLNPLIKLNGGYLVDDSDADASLFINVCRDIDSLRDPSTQLRVCPAGTAACLLKGNQAFDVGRPKEGLKLLSKDRLVLTYVKEEGEKPDFCNGHSPAVTVTFVCPSERREGTIPKLTAKSNCRYEVEWITEYACHRDYLESETCSLSSEQHDIAIDLSPLAQHEEGSPYVADGGEYRFFMNVCGDTKVSLCNKEAAVCQEKKVDSTQVKIAGRHQNQTLRYSDGDLTLIYSGGDECSSGFQRMSVINFECNKTAGQDGRGEPVFTGEVDCTYFFTWDTKYACVKEKEDLLCGAIDGKKRYDLSVLARHSESEQNWEAVDGSQAESEKRNFFINVCHRVLQAGKAKNCPEGAAVCAVDKSGSKNLGKFVSSPTKEKGHIQLSYSDGDDCGNDKKITTNITFVCKPGDLESAPVLRAAGPDGCSYEFEWHTAAACVLSQTEGENCTVLDAQAGFSFDLSLLTKKNGAYKVETDKYDFYINVCGPVSVNLCQSNSGACQVAKSGKSWNLGLSNTKLTYYDGMIQLSYRNGTLYNNEKHTPRSTLITFLCDRDAGVGFPEYQEEDNSTYNFRWYTSYACPEEPLECMVTDPSMMEQYDLSSLVKFEGGRGGNWYAMENSREHFTRRKYYLNVCRPLNPVPGCDRYASACQMKYENNEGSLAETVAISNLGVAKTGPVVEESGSLLLEYVNGSACTTSDGRLTTYSTRIHLVCGRGTMNSHPIFTFNWECVVSFLWNTEAACPIQTITDSDQACSIRDPNSGFVFNLSPLNYSQGHMVLGIGKTFVFNICGTMPACGTVAGKPALGCEAETKIKDIKDLKPERPVGMEKSLQLSAEGFLTLTYKGSSPSDRGTAFIIRFICNGDIYPGTPKFLHQDIDSARGIRNTFFEFETALACIPSVVDCQVTDPAGNEYDLSALSMVRKPWTAVDTSVHGKKRRFYLSVCTPLPYIPGCDGIAMGSCMVSEDKSQNLGVVQISPQATGNGSLSILYVNGDRCGNQRYSTRIVFECAQTSGSPMFQLLNNCEYVFVWRTVEACPVVREEGDNCQVKDPRHGNLYDLKPLALNDTIISAGEYTYYFRVCGKLSLDVCSAHDGSKAVSSCQEKKGPQGFQKVAGLLNQKLTFENGLLKMNYSGGDTCHKVYQRSTTIYFYCDRTTQKPVFLKETLDCSYLFEWRTQYACPPFNVTECSIQDEAGNSIDLSSLSRYSDNWEAVTRTGATEHYLINVCKSLSPQAGTDPCPPEAAVCLLDGSKPVNLGRVRDGPQWTAGVTVLKYVDGDLCPDKIRKRSTIIRFTCSDSQVNSRPLFISAVQDCEYTFSWPTPAACPVKSNIHDDCQVTNPSTGHLFDLSSLSGKAGITASYSEKGMVFMSICEENVNCSPGVGACFGQTRISVGQASKRLSYKDQVLQLVYENGSPCPSKSGLRYKSVISFVCRPEAGPTNRPMLISLDKQSCTLFFSWHTPLACEQATECTVRNGSSIIDLSPLIHRTGGYEAYDESEDDTSDTTPDFYINICQPLNPMHGVPCPAGASVCKVPVDGPPIDIGRVTGPPIFNPVANEVYLNFESSTPCLADKYMNYTSLIAFHCRRGISMGTPKLIRNNDCDFVFEWETPIVCPDEVKTQGCAVTDEQLLYSFNLTSLSTSTFKVTRDAHTYSIGVCTTAADLDQEGCKDGGVCLLSGSKGASFGRLASMQLDYRHQDEAVILSYVNGDPCPPETEDGEPCVFPFIYKGETYDECVLEGRAKLWCSKTANYDRDHEWGFCRPSNSHRMSAIIFTCDENEDIGRPEVFSEDRGCEVTFEWKTKVVCPPKKMECKFVQKHKTYDLRLLSSLTGSWDFVHEGNSYFINLCQRVYKGPLDCSERASICKKSATGQVQVLGLVHTQKLEVIDETVLVTYSKGHSCGGNKTASSVIELTCAKTVGRPAFKRFDIDSCTYYFYWYSRAACAVRPQEVNMVNGTLTNPVTGKSFSLGEIYFKLFSASGDMRSNGDNYLYEIQLSSISSSSNPACSGANICQVKPNDQHFSRKVGTSDMTKYYVQDGDLDVVFTSSSTCGKDKTKSVSSTIFFHCDPLLKDGVPEFSHETADCQYLFSWYTSAVCPLGVDFDDENAVPEYKGLSERSQAVGAVLSLLLVALTGCLLALLLHKKERRETVINKLTNCCRRSSGVSYKYSKVSKEEETDENETEWLMEEIQVPAARLGKDGQENGHITTKTVKAEALTSLHGDDQDSEDEVLTIPEVKVHTGRGAEVESSQPLRNPQRKVLKEREGERMGLVRGEKARRGKFRPGQRKPTTPAKLVSFHDDSDEDLLHI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0036094 (small molecule binding), GO:0016740 (transferase activity), GO:0008289 (lipid binding), GO:0043167 (ion binding), GO:0038023 (signaling receptor activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0019838 (growth factor binding), GO:0004888 (transmembrane signaling receptor activity), GO:0001965 (G-protein alpha-subunit binding), GO:0043177 (organic acid binding), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0019840 (isoprenoid binding), GO:0004672 (protein kinase activity), GO:0043168 (anion binding), GO:0019899 (enzyme binding), GO:0016301 (kinase activity), GO:0005501 (retinoid binding), GO:0019199 (transmembrane receptor protein kinase activity), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0031406 (carboxylic acid binding), GO:0004713 (protein tyrosine kinase activity), GO:0005520 (insulin-like growth factor binding), GO:0001972 (retinoic acid binding), GO:0004714 (transmembrane receptor protein tyrosine kinase activity), GO:0033293 (monocarboxylic acid binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0000003 (reproduction), GO:0019953 (sexual reproduction), GO:0051641 (cellular localization), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0042221 (response to chemical), GO:0050794 (regulation of cellular process), GO:0051234 (establishment of localization), GO:0051716 (cellular response to stimulus), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0033036 (macromolecule localization), GO:0009791 (post-embryonic development), GO:0048522 (positive regulation of cellular process), GO:0007276 (gamete generation), GO:0010942 (positive regulation of cell death), GO:0010941 (regulation of cell death), GO:0007186 (G protein-coupled receptor signaling pathway), GO:0048731 (system development), GO:0006810 (transport), GO:0048513 (animal organ development), GO:0070727 (cellular macromolecule localization), GO:1901700 (response to oxygen-containing compound), GO:0031099 (regeneration), GO:0010033 (response to organic substance), GO:0007283 (spermatogenesis), GO:0045184 (establishment of protein localization), GO:0031100 (animal organ regeneration), GO:0071705 (nitrogen compound transport), GO:0043067 (regulation of programmed cell death), GO:0033993 (response to lipid), GO:0015031 (protein transport), GO:0043068 (positive regulation of programmed cell death), GO:0048732 (gland development), GO:0071702 (organic substance transport), GO:0008104 (protein localization), GO:0048232 (male gamete generation), GO:0061008 (hepaticobiliary system development), GO:0032526 (response to retinoic acid), GO:0043065 (positive regulation of apoptotic process), GO:0042981 (regulation of apoptotic process), GO:0001889 (liver development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0048471 (perinuclear region of cytoplasm), GO:0071944 (cell periphery), GO:0098796 (membrane protein complex), GO:0031984 (organelle subcompartment), GO:0005615 (extracellular space), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005576 (extracellular region), GO:0030117 (membrane coat), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0048475 (coated membrane), GO:0098791 (Golgi apparatus subcompartment), GO:0005794 (Golgi apparatus), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0030118 (clathrin coat), GO:0005770 (late endosome), GO:0005802 (trans-Golgi network), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)