Protein: [histone H3]-trimethyl-L-lysine(27) demethylase (A0A8M2BG42)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
- IPR019734: Tetratricopeptide repeat (repeat) [93-385]
- IPR051630: Transcriptional Corepressor and Histone Demethylase (family) [30-1348]
- IPR048562: Lysine-specific demethylase 6A/B-like, C-terminal helical domain (domain) [1202-1256]
- IPR046941: Lysine-specific demethylase 6, GATA-like domain superfamily (homologous_superfamily) [1267-1334]
- IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [70-425]
- IPR003347: JmjC domain (domain) [1049-1212]
- IPR048560: Lysine-specific demethylase 6A/B-like, GATA-like (domain) [1274-1335]
Sequence:
MKPCRVSVAAAAARRLSAAGDEEKKMAAGKASEPEEESPRLSAQESDTLARVDSSLFGYQRLHEDGASMKALLVKAVRCYESLILKAEGKVDPEFFCQLGHFNLLLEEYPKALSAYQRYYSLQSDYWKNAAFLYGLGMVYFHYNAFQWAIKAFQEVLYIDPGFSRAKEIHLRLGLMFKVNTDYESSLKHFQLALIDSSRCTLSKAEIQFHIAHLYEIQKRHRAAKEAYESLLQTEDLQTPVRAAALQQLGWMHHTVEQLGDKANKDSYAIQCLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHSHAAAWMDLGTLYESCNQPHDAIKCYINATRSKTCSNTAALAARIKYLQAQFCKLRLNSLQGKSKTLPNIEEAWSLPIPAELTSRQGVQSTGPQACKAQPGASSGSQASAPALPPHSTALEPAGAQTSPARRRRSSSPAQSSTDSWSSGSAHTPVPHWYLTPQKLQLLEQLRASRASLKPAQLQMLEQMEAQLSAMHLHQQQMRQNSSGQIRPSLSNGPSLPASRGPALQTLHNGPGPRPGPQTPAVRNNHTESRANGDVPYLHPNTLPHNCTSPGAGRRSPQLPPAQGLQKGPGSHWAGPNGIRSDSSSGSADGGPHNQVVDSASAGDAAGSSGSPPPRRCSPCALPHTATSGAPHSTIPTKESAALQANGSTATDTHSPASPHRPPSPVSATTTDNPPLPNLQTLPATAPAAPLTPVGSTLPAPGSSSASSPASALSAASPSPRPGDPTTPLRPLQAPVTVNGCSEDSRSPLKLEPEQSITSSAAHRSASISIYPTSTDALKACRSLGRNGLSSCSLLLNRCPPPRLPPPPAPPLDKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPSNPVTVIRGLAGALKLDLGLFSTKTLVDMNPEHLVEVRTQLSQPADENWDASGTRKQWRCESTRSHTTIAKYAQYQAASFQESLREENEKKGQKELSDSEIASSESVCRRRKGPFKQVKFGMNIDVSDEKKWKLQLQELSKLPAFARVVSAGNLLSHVGHRILGMNTVQLCMKVPGSRTPGHQEHNNFCAVNINIGPGDCEWFAVPEPYWGVMSEFCERNNINFLKGSWWPNLEDLYEARVPVYRFIQRPGDLVWLNTGTVHWGQAIGWCNNISWNVGPLTAHQYKLAVERYEWNKLQSVKSMVPMVHLSWNMARNIKVADQRLFEMIKFCLLRTLRQTQSIRESLLSAGKETLWQRRSRDEPAHYCSVCEVEVWNLLFVCSEGSPCRPAAAVQCQDCARKASVDLQGFVVLQQFRMEDLTQLYEQFSLAPALHSSSS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0032451 (demethylase activity), GO:0140457 (protein demethylase activity), GO:0032452 (histone demethylase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0019953 (sexual reproduction), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048870 (cell motility), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0032504 (multicellular organism reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0007389 (pattern specification process), GO:0007276 (gamete generation), GO:0008354 (germ cell migration), GO:0048513 (animal organ development), GO:0003002 (regionalization), GO:0060322 (head development), GO:0048731 (system development), GO:0016477 (cell migration), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development), GO:0072359 (circulatory system development), GO:0009952 (anterior/posterior pattern specification), GO:0007507 (heart development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0032993 (protein-DNA complex), GO:0140535 (intracellular protein-containing complex), GO:1990234 (transferase complex), GO:0000151 (ubiquitin ligase complex), GO:0031461 (cullin-RING ubiquitin ligase complex), GO:0019005 (SCF ubiquitin ligase complex)