Protein: Circadian locomoter output cycles protein kaput (A0A8M9PH45)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytosol
InterPro domains:
- IPR047230: Circadian locomoter output cycles protein kaput-like (family) [17-827]
- IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [22-109]
- IPR001067: Nuclear translocator (family) [40-283]
- IPR001610: PAC motif (repeat) [327-370]
- IPR011598: Myc-type, basic helix-loop-helix (bHLH) domain (domain) [25-81]
- IPR000014: PAS domain (domain) [98-364]
- IPR013767: PAS fold (domain) [101-169]
- IPR035965: PAS domain superfamily (homologous_superfamily) [109-367]
Sequence:
MTSSIDRDDSSIFDGLMEEDEKDKAKRVSRNRSEKKRRDQFNVLIKELGTMLPGNTRKMDKSTILQKSIDFLRKHKEIAAQSESSEIRQDWKPPFLSNEEFTQLMLEALDGFFLAIMTDGNIIYVSESVTSLLEHLPSDLVDQNLLNFLPLGEHSEVYKALSTHMLEGETLTPDYLKTKNQLEFCCHMLRGTIDPKEPPVYEYVKFIGNFKSLNTVPNSTRNGFEGVIQRSLRHAFEDRVCFIATVRLAKPQFIKEMCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLETLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVVSYAEVRAEQRRELGIEESPPEISADKSQDSGSESQLNTSSLKEALERFDHSRTPSASSRSSRKSSSHTAVSDPTSTQTKLQTDRSTPPRQSVSAIEMTSQRRSSISSQSMSSQTTGQTMGTSLVSQPQQPQTLQATVQPVLQFSTQMDAMQHLKEQLEQRTRMIEANIQRQQEELRQIQDELQRVQGQGLQMFLQPSGGGLNLSSVQLTQSSSVQTAGTLSMQGAVVPTATLQSSLQSTHSSTQHTVTQHPQQTAVQQQNLLRDQTTNLNQSQRSTHTLQSPQGALPASLYNTMMISQPTQANVVQISTSLAQNSSTSGAAVATFSQDRQIRFPATQQLLTKLVTGPMACGAVMVPTTMFMGQVVTAFAPQQGQPQTISIAQQPSAQTADQQTHTQAQTQAAATAQQQGQNQAQLTQQQTQFLQAPRLLHSNQSTQLILQAAFPLQQQGTFTTATQQQQQLHQQQQQLQQQQQLQQQQQQQQQQLQQQHQQQQQQLQQQHQQQQQQLAAHRSDSMTERSNPPPQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific), GO:0003677 (DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0048511 (rhythmic process), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0009628 (response to abiotic stimulus), GO:0048856 (anatomical structure development), GO:0048869 (cellular developmental process), GO:0007275 (multicellular organism development), GO:0019222 (regulation of metabolic process), GO:0007623 (circadian rhythm), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0048522 (positive regulation of cellular process), GO:0009266 (response to temperature stimulus), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0009314 (response to radiation), GO:0048513 (animal organ development), GO:0060255 (regulation of macromolecule metabolic process), GO:0009891 (positive regulation of biosynthetic process), GO:0009888 (tissue development), GO:0031325 (positive regulation of cellular metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0009790 (embryo development), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0032922 (circadian regulation of gene expression), GO:0030097 (hemopoiesis), GO:0009416 (response to light stimulus), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010628 (positive regulation of gene expression), GO:0010468 (regulation of gene expression), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0048568 (embryonic organ development), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0007498 (mesoderm development), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0009648 (photoperiodism), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0035162 (embryonic hemopoiesis), GO:1902680 (positive regulation of RNA biosynthetic process), GO:0006357 (regulation of transcription by RNA polymerase II), GO:0045893 (positive regulation of DNA-templated transcription), GO:0060215 (primitive hemopoiesis), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0045944 (positive regulation of transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005667 (transcription regulator complex), GO:0000785 (chromatin), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome)