lokahq/bioreason-rl huggingface dataset:
Protein: Collagen alpha-2(XI) chain isoform X3 (A0A8M2B6G1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
Sequence:
MDIRKKRRPWCMETSFVLLLCLSMAQADPVDVLRVLQLPSLPEGVQKVPGFCTSRLSGTPDHAYRITKKAQISAPTKQLFSGRFPENFSIMTLVKAKAGLQAFLLSIYNEQGVQQLGLELGRSPIFLYEDQHRKPAPEDYPLFKGVNLADGKWHRIAISVQKKNITLILDCKNRITKTLPRSNNPVLDTKGITVFGARLLDEEVFQGEIQQLLIASNPQAAYDFCEHYSPDCDSPLPKVQSQDPNTYAGKANNGKVTKQKTAPAAKPAPAKPAKSKPTPAPKTAKSKPTAAQLLISKIKPTPASKLAAKPKATPAPKNDKKKTNDNGKVNNGQTKVNGNGNGKSNGNGKDTNGKAKAGSNGKPNNNGNGNGKKTNGDAKINGNGPKTVKTVTKVASAKKSETPATKTVTGKPKAQVKAQPTKSKTDKTKANASPAKPKDTKAKAASVTQKPAVFKPTPVPLPRPSKTILDVNNVKSMSRNFPPFDKAVVSATTIKKKPTNGYQQASVRAIKGEKGEPAVLEPGMLIEGPPGPEGPAGLPGPSGPQGQPGSVGDPGERGPTGKAGLPGADGVPGPPGTSVMLPFRFGQSAGEKGPVASAQEAQAQAILSQARLALKGPSGPMGFTGRPGPLGTPGSPGFKGERGDPGAQGPRGPQGVSGPPGKAGRRGRAGADGARGMPGESGIKGDRGFDGLPGLPGDKGYRGQPGGMGPPGPHGEDGERGDDGDVGPRGLPGEPGPRGLLGPKGPSGLPGPPGVRGNDGPHGPKGNLGPQGEPGPPGQQGAPGTQGMPGPQGATGPPGEKGPTGKPGLPGMPGADGPPGHPGKEGPGGTKGNQGPNGPQGSIGYPGPRGLKGAQGIRGLKGHKGEKGEDGFPGIKGDFGVKGERGEVGVPGPRGEDGPEGPKGRVGPPGEIGPLGLLGEKGKLGVPGLPGYPGRQGIKGSLGFPGFPGTNGEKGTRGLIGKPGPRGQRGPTGPRGQRGPRGATGKSGAKGGSGSDGPPGPPGERGLTGPQGANGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKVGPPGPPGVVGPHGPSGETGQMGERGHPGPPGPPGEQGLSGSSGKEGTKGDPGPPGGPGKDGPPGLRGFPGERGLPGTPGSGGLKGNEGPAGPPGPAGSSGERGGAGTAGPVGPPGRPGPQGPPGTSGEKGVPGEKGPVGPAGRDGIQGPVGLPGPAGPPGISGEDGDKGEVGEPGQKGAKGSKGEHGPPGPPGPMGPVGQPGAAGADGETGPRGQQGQFGAKGDEGTRGFPGPPGPIGLQGLPGPGGEKGETGDVGPLGPPGPPGPRGPAGPNGADGPQGPPGGLGNPGPIGEKGEPGESGPPGVGGEPGKLGPRGERGEKGESGQPGTPGPPGGKGPTGDDGPKGNPGPVGFPGDPGPPGEVGPRGQDGAKGDRGEDGEQGEAGSPGPTGENGPPGPPGKRGPAGTRGPEGRQGEKGSKGDSGALGPPGKTGPVGPQGQPGKPGTEGLRGLPGTVGEQGSPGAAGPKGPPGPLGPPGLAGLRGDPGAKGEKGHPGMLGLIGPAGEQGEKGDRGMPGPQGSTGPKGETGISGGTGPLGPAGPAGMPGPRGVKGAKGASGGAGPKGEKGVQGPPGPPGPPGDVIQPLPIQIPKKSKRSIDASKILSEADAEAADTTGSEFLTGNEGMEEIFGSLNSLRQEIESMRFPLGTKESPGRTCQDLHLSQPDLKDGEYWIDPNQGCARDSFKVYCNFTAGGETCLYPSKAVENVKMNSWIKEKPGSLFSQFAKGNKFSYVDSVGEAVGVVQLGFLRLLSVQARQNLTYHCQRSVAWTDQTTDGGYKRALRLQGANDEEISYETSPYIKALIDGCSYRKGLDRTVLEVNTPQVEQLPLLDIRISDFGEDNQKFGFEVGPVCFLG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0005201 (extracellular matrix structural constituent)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0098743 (cell aggregation), GO:0009887 (animal organ morphogenesis), GO:0001502 (cartilage condensation), GO:0009888 (tissue development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0051216 (cartilage development), GO:0048705 (skeletal system morphogenesis), GO:0001501 (skeletal system development), GO:0061448 (connective tissue development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Bridging integrator 1b isoform X3 (A0A8M3AT25)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR004148: BAR domain (domain) [16-275]
- IPR001452: SH3 domain (domain) [493-564]
- IPR027267: AH/BAR domain superfamily (homologous_superfamily) [9-276]
- IPR003005: Amphiphysin (family) [1-563]
- IPR036028: SH3-like domain superfamily (homologous_superfamily) [489-563]
Sequence:
MAEVGKGVNAGKLASNVQKRLTRAQEKVMQKLGKADETKDTAFEEQVANFNKQMNEGTKLQKDLKAYLLAVKTMHECSKRLHDCLAEMYDPEWFGKEEVDSIAEDTDLLWQDFHEKLLDNAVISMDAYLAQFPDIKARIAKRERKLVDFDSARHHFASVQKGKKKDEAKIAKPLALVEKAAPVWAQGILTAHQIAQTNLTRNQAEEDLGRAQKVFEEINYDLQEELPTLWNSRVGLYVNTFRSVSGLEETFHRDMGKLNQNLSDIMTKLEEQRVAKKGVTTASTGKSDDAANHNQETSDAPKSPSKLRDVPPVSRPPRPASSQEVKPDKIINLFEDAEVSDSNTTTQPEQGASWNSWEPAQSPAVSPSQQWDSDNEADAQPHGQPYAAPEWDDDVTPAVQSYEPPSWDEQDGAPAQSGWDGQTAAPAQPDWEDEHWDEEGSQVGQVQDTETNWANDAAQDWEAESEPPQWEELQSNEAPTVTNGSSDTELPPSVLFKVKTMHDYSATDSDELDLKAGDIVLVLPFANPDEADDGWLMGVKESHWLQNKNLLAKGVFPENFTQKL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0003008 (system process), GO:0003012 (muscle system process), GO:0003013 (circulatory system process), GO:0003015 (heart process), GO:0008015 (blood circulation), GO:0006936 (muscle contraction), GO:0006941 (striated muscle contraction), GO:0060047 (heart contraction), GO:0060048 (cardiac muscle contraction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0030017 (sarcomere), GO:0031674 (I band), GO:0030018 (Z disc), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043292 (contractile fiber), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0016528 (sarcoplasm), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0016529 (sarcoplasmic reticulum), GO:0043231 (intracellular membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0030016 (myofibril), GO:0043232 (intracellular non-membrane-bounded organelle)
Protein: Protein kinase C (A0A8M9PM31)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm. Mitochondrion membrane; Peripheral membrane protein
InterPro domains:
- IPR002219: Protein kinase C-like, phorbol ester/diacylglycerol-binding domain (domain) [34-151]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [466-478]
- IPR000719: Protein kinase domain (domain) [346-604]
- IPR000008: C2 domain (domain) [156-274]
- IPR000961: AGC-kinase, C-terminal (domain) [605-675]
- IPR034663: Classical Protein Kinase C alpha, catalytic domain (domain) [335-675]
- IPR017892: Protein kinase, C-terminal (domain) [631-665]
- IPR014375: Protein kinase C, alpha/beta/gamma types (family) [5-673]
- IPR017441: Protein kinase, ATP binding site (binding_site) [352-375]
- IPR035892: C2 domain superfamily (homologous_superfamily) [154-290]
- IPR020454: Diacylglycerol/phorbol-ester binding (domain) [32-150]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [342-656]
- IPR046349: C1-like domain superfamily (homologous_superfamily) [23-152]
Sequence:
MADTQSNEQSSSDVANRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHELVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDSCDMNVHKQCVMNVPSLCGTDHTERRGRLYMKIEVIGDKMHVTVGEGKNLIPMDPNGLSDPYVKLKLIPDPKNETKQKTKTIRSSLNPTWNETFTFKLKPADKDRRLAVEVWDWDRTTRNDFMGSMSFGVSELMKSPVCGWYKMLNQEEGEYYNVPIPDEDDPDTELRQKFEDETLEDLEQIAKLGPPKKNITALDDSGSSITSSNVDNVRLSDFNFLAVLGKGSFGKVMLAEMKSSDELFAIKILKKDVVIQDDDVECTMVEKRVLAQQDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEIAVGLFFLHKKGIIYRDLKLDNVMLDAEGHIKIADFGMCKENIVEGVTTRTFCGTPDYIAPEIIAYQPYGRSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYSKTLSKEAVSICKGLMTKHPSKRLGCGQEGERDIREHAFFRRIDWDRLANREVQPPFKPKVCGKGAENFDKFFTRTQPQLTPPDELVIANIDQADFDGFTFVNPQFVHPSLVNTE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity), GO:0004697 (protein kinase C activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0065007 (biological regulation), GO:0032501 (multicellular organismal process), GO:0050817 (coagulation), GO:0065008 (regulation of biological quality), GO:0006950 (response to stress), GO:0009611 (response to wounding), GO:0050878 (regulation of body fluid levels), GO:0007596 (blood coagulation), GO:0042060 (wound healing), GO:0007599 (hemostasis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Tryptophan 5-hydroxylase 2 (A0A8M1P7E6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR018301: Aromatic amino acid hydroxylase, iron/copper binding site (binding_site) [370-381]
- IPR002912: ACT domain (domain) [108-183]
- IPR036329: Aromatic amino acid monoxygenase, C-terminal domain superfamily (homologous_superfamily) [207-540]
- IPR019773: Tyrosine 3-monooxygenase-like (family) [72-542]
- IPR036951: Aromatic amino acid hydroxylase superfamily (homologous_superfamily) [93-541]
- IPR005963: Tryptophan 5-monooxygenase (family) [95-541]
- IPR001273: Aromatic amino acid hydroxylase (family) [90-545]
- IPR019774: Aromatic amino acid hydroxylase, C-terminal (domain) [195-541]
- IPR045865: ACT-like domain (homologous_superfamily) [105-212]
- IPR041904: Tryptophan 5-hydroxylase, catalytic domain (domain) [208-494]
Sequence:
MQGKKTSQETTATMSNELQTNPKGQQTAPKSPVGLLRKRGQEAIPKMQPAMMMFSSKYWARRGLSLDSAMYDQQHLASSMLRRTSFNRIDERPDKEEQKSTHDLGKLAVIFSLKNEVGFLVKALRLFQEKHVNLAHIESRRSKRLTNEIEIYAECNCTKKEFNELVQHLKDHVNIVSYNTPQHVWSAETDCLDCVCVLGGLPDGEGIPWFPQKISELDQCSHRVLMYGSELDADHPGFKDKVYRQRRKYFVEVAMNYKFGQPIPRIEYTAEEVKTWGVVYRELTKLYPTHACREYLKNLPLLTKHCGYREDNIPQLEDVSLFLRERSGFTVRPVAGYLSPRDFLAGLAYRVFNCTQYIRHSTDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQDGQLRVYGAGLLSSIGELRHALSDKATVKVFDPKTTCYQECLITTFQDVYFVSESFEEAKEKMREFAKSIKRPFSVYYNPYTQSIDLLKDTRSIENVVQDLRSDLTTVCDALGKMNKYLGI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen), GO:0004497 (monooxygenase activity), GO:0016714 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050793 (regulation of developmental process), GO:0050794 (regulation of cellular process), GO:0045595 (regulation of cell differentiation), GO:1901532 (regulation of hematopoietic progenitor cell differentiation), GO:2000736 (regulation of stem cell differentiation), GO:1902036 (regulation of hematopoietic stem cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0042995 (cell projection), GO:0120025 (plasma membrane bounded cell projection), GO:0043005 (neuron projection)
Protein: U3 small nucleolar RNA-associated protein 4 homolog isoform X1 (A0A8M2BH80)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
Sequence:
MVKHPKERERKHTKRGSAMGEFKVHRVRFFEYVPSGIRALAFNQHNERMAAAKMNGSVEIFHCSDRFFQEKIIPGREQAGIEGLTWVGERLFSAGLNGVITEYDLTNQRVKYTIDAYGGPIWAITGNQQGTHLAVGCEDGTVKLFEVTEDKIQFERNLDRQKGRIISLSWHPSGSKIAAGMMDMIQVFNVETGHSKHRILVDRGYGTSRGKECVVWSVVYLSDGTIISGDSVGMVKMWRDDTGTLIKSHNITKSDVLSLSVSQNEDSIVAGTSEGFVVQFQFLSMVLENNEKDWVRTRTFRNHTHDVRAVAEITTAVVSGGMDTQLVVRPLLDKHEVKSSASKLRKIQFPHRSLVSCARKAGTLLFQYPGHLELWRLGESEGEGIPGSSLLLKRKPEKLLHLKVKGEDHIRCSAVSPCGEWIAYSTTSSLRLYKLHCDSNNVSITKISKLPKVLGSASQLCFSSDSTHLFSASTQSSVHMVSLSQPECKFVATFKTKSGSHQAIHLLAASEDGKWLASANIDNEVHIYNLQTRKAHCTVPIYSSAVSAMAIHPTTNCLFMVHADQQIFEFSIEQKEYTDWSRLVQRQGLHRIWLERDTPCLNVTFNQKNPSHVILHDMYMFCIIDQSQPLPDSKSQFLNQLTLRSLPEEQRKSYSHAFKVCKTFKELLCVDVMGDQSLVVVERPLEDITAQLPAPIKQKKFAT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0003008 (system process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex)
Protein: Ribosomal protein S6 kinase alpha-3 isoform X3 (A0A8M3AZ29)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [152-510]
- IPR000719: Protein kinase domain (domain) [31-642]
- IPR041906: Ribosomal S6 kinase, N-terminal catalytic domain (domain) [35-351]
- IPR000961: AGC-kinase, C-terminal (domain) [291-360]
- IPR017892: Protein kinase, C-terminal (domain) [314-350]
- IPR016239: Ribosomal protein S6 kinase II (family) [8-701]
- IPR017441: Protein kinase, ATP binding site (binding_site) [37-414]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [29-678]
Sequence:
MCVAWEEVSVKEINITHLVKEGSEKADPQQFELRKVLGQGSFGKVFLVKKTTGPDAGQLYAMKVLKKATLKVRDQVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHGLGIIYRDLKPENILLDEDGHIKLTDFGLSKESIDHENKAYSFCGTVEYMAPEVVNRRGHTYSADWWSYGVLMYEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSSEAQSLLRSLFKRNPTNRLGAGPDGVEEIKRHPFYVSIDWNKLFRRESHPPFKPATGRPDDTFYFDPEFTAKTPKDSPGVPPSANANRLFRGFSFVAITSEEESQSLPSNSMSSIVQQLHRNVSQFSDAYEVKEDIGIGAYSICKRCIQKSTMMEYAVKIISKAKRDPAEEVEILLRYGQHPNIITLKDVYDDGRTVYLVTELLKGGELLDKILRQKFFSEREACAVLHTITKTVAYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKKQGYDAACDIWSLGVLLYTMLTGFTPFANGPEDTPEEILARIGSGQFSLTGGFWNSVSCQAKDLVSKMLHVDPHQRLTAAQVLKHPWITHKDKLPNYQLNRQDAPHLVKGAMAATFSALNRNIPPVLEPVGCSILAQRRGVKKLTSTAL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0001503 (ossification)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: X-linked interleukin-1 receptor accessory protein-like 2 isoform X1 (A0A8M9QP14)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
Sequence:
MRLILDCKAFFGYSGDSKPIIYWMKGDKFVEELEGHIRESEVRVVREFLGEKEVELSLVFDAVEDTDMGNYTCNVENHIGRGSGSAILQKKDMYRLELVGGLGAIMLLLGIFTAIYKCYNVEIMLCYRQHFGSDEADDGNKEYDAYLSYTKVDLDSVEQEMSEEEQFALEILPDVLEKHYGYKLFIPHRDLIPSSTYIEDLARSVEQSRRLIIVLTPEFVARRGWSIFQFEPRLHSMLVTGEIKVIMIECPDLRSVINYQEVEDLKHTIRVLTLIKWQGPKSNQLKSKFWKQVRYEMPAKKKETMSRRQVLDSGEQGLFGDLQAVSTVAMTATSASLAPTQVEIPDYNEPSHMQMRHFCRSYEYELPTTAIATLNGRHMYCNLPMTLLNGRLTQNNIGKGKKEIHLNSSFVPLSGQELSSDIW
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023057 (negative regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0010646 (regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0030111 (regulation of Wnt signaling pathway), GO:0030178 (negative regulation of Wnt signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)
Protein: Methyl-CpG-binding domain protein 6 isoform X2 (A0A8M3BAP7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
Sequence:
MTGGSESVAGEKDGGTTLIAQVPVGWRRKVEDGAVSYISPSGTVLQSVDEVRVYLRTDGTCKCGLECPLVPNKVFNFDPAAMVQAPGHQSGKVEEDMTKLCNHRRKVDAMTALCQSMHPSHLAPLAQATGGVVCSVDGRESRGSMLTHGDGAHCTYPQPRHSQPKPNMGFPLSSSRSVLQNGSVNLSPISRPPDQGSPLKKSQAPVYAKQQWSPHPPLIQNTPQRTAHNPTSPNNVKPTQAHPPDSINSFSFSSSLSNRTIPPMSQGASVKSPSPLSPSRTRDSFSPHQRSRHSSTSSLSDHQIFIQGAKPLHPTMPCSSPKLPNAPLSPCSRLEGILQHYKDCSTSSSISTSANQSIHQASLVALPNASDKRNGAMLGQILNQKQKSHINNSFPASSLLSAAAKAQLANQKTEGLSALPLAGLDKEQQSKGTLSSPALVSTSVSCGPLVSAGPEVCDPLAEQDKNSQTHHFLSPLLAPGVLGDLAALGNINSLHGLLGAGPLLLPQGVPLTQNQTTLNPLTCLQLTMAPALMGEKPVALHETPPPQDAAAPPHDSLSQQREAPGLFDPYGSFMDTIYTSFLQVSERGSDSNPLTFPALLQQASAPPSLSPRRACSVHNPDLSRLGPDVAQSPARGTPKPSGDSPPPPCRPAGAHALTVEEAKTHTSKHCVFSNGLRSEGGEEEEEEDEDEDAGVQEYLSPTQRTSRDEDEDISHAEQIRAEDVHTGSRRGRKRKQTLQMGSDLPGGIDSIIEEPSASAILVSRSSRSSRGKRRRVLR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding), GO:0005515 (protein binding), GO:1990841 (promoter-specific chromatin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0030154 (cell differentiation), GO:0048468 (cell development), GO:0002244 (hematopoietic progenitor cell differentiation), GO:0030097 (hemopoiesis), GO:0060216 (definitive hemopoiesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Formimidoyltransferase-cyclodeaminase (A0A8M1PIL2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Binds and promotes bundling of vimentin filaments originating from the Golgi
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Golgi apparatus
InterPro domains:
- IPR012886: Formiminotransferase, N-terminal subdomain (domain) [3-180]
- IPR037064: Formiminotransferase, N-terminal subdomain superfamily (homologous_superfamily) [2-181]
- IPR051623: Formiminotransferase-cyclodeaminase (family) [2-330]
- IPR022384: Formiminotransferase catalytic domain superfamily (homologous_superfamily) [3-326]
- IPR004227: Formiminotransferase catalytic domain (domain) [1-326]
- IPR036178: Formimidoyltransferase-cyclodeaminase-like superfamily (homologous_superfamily) [325-538]
- IPR007044: Cyclodeaminase/cyclohydrolase (domain) [339-519]
- IPR013802: Formiminotransferase, C-terminal subdomain (domain) [181-325]
- IPR037070: Formiminotransferase, C-terminal subdomain superfamily (homologous_superfamily) [182-324]
Sequence:
MAKLVECVPNFSEGRNKEVIDAIANAISATEGCSLLDVDPGSSTNRTVYTFVGSPTTVIEGALNAARVAFKLIDMTKHSGEHPRTGAMDVCPFIPVQNVTMEECVQCANEFGQRLADMLHVPVYLYGEAARKESRRSLPSVRAGEYEALPDKLKKSEWAPEFGPATFVPSWGATVTGARKFLVAYNVNLLSTKEQAHRIALDIREQGRSKDQPGLLKKVQGMGWYLEESNLAQVSTNILDFELTPMHTVYEEICRDAKDLNLPVVGSQIVGLIPLKAMLDCADFYIKREKLFVVEEEHKIRLVISKLGLDSLGPFDPKERIIEYMVQNNQDDGRLVSLSLQKFVHSVGARTAAPGGGSVSAAIAAMGAALGCMVGQMTYGKRQFESLDGEMRKLIPPFHEAMNDLLLKVDADSTAFNSYMAALKMPKGTTDEIKRREEAMQEGLKAAVRVPLSLAERINTLWPHIKEMVKYGNVACKSDIQVAAKALETAVYGAYFNVIINLKDITDASFRASTEAKVSALLKSSRENANIALETADQRK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016829 (lyase activity), GO:0016741 (transferase activity, transferring one-carbon groups), GO:0016840 (carbon-nitrogen lyase activity), GO:0016841 (ammonia-lyase activity), GO:0016742 (hydroxymethyl-, formyl- and related transferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009790 (embryo development), GO:0048598 (embryonic morphogenesis), GO:0007369 (gastrulation), GO:0001702 (gastrulation with mouth forming second)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Centrosomal protein of 83 kDa isoform X2 (A0A8M3ARI8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR052116: Centrosome and Cilium Assembly Protein (family) [48-704]
Sequence:
MNPPALGQASALFPDLEPPGGVGKATVLLGGSTGLTSSDMEFQKMLIDERMRCENHKTNYQTLKVEHTRLQDQYTRAQNELKRLLSDRQVTQEKQQLLLAELRGELLDKTRDLEELKLQVLTPQRLELLRAQVQQELEAPIRERFNKLQEEAENYRSEYNKLRYDLTFLKSEFDHQKEEHARVLEERRIRHEADVARLEHDKEDLATQLQSGDPARDGKRVEALLREKAQLHQRLRGLEAEVTELRAERNNSGAQAENVQRIQIRQLAESQAAVKALEAEKQSIRMQLDRTESELRLSQEQNTLLTGKLHKAEREINSLNSQVEEMKHTHKLELSNVKLECVRSKGELERERDMLQCQVEGLQSDIEVMKSALERNKELISEKEREMVRRVQAAREEEIHKMATLQEEKLELENRLSELEQQKALQEVTGNSQKEEWEERLRAAQLGEESVRKELQNLRTKVQQQGQQLEELETLKAENADLRQQIAELNLQVGTLSHSESELLDTNNRLRESLERVREDLRSARTQMERTQQEAERLVEERRVEWLEEKHKLQDIEAELREKYSQAKERLQRAAFAQKKRKTMTELKENKLKDKIQLLEAKIAELEIEASAEKKKSSYSEEHAQLSKRLRELQRRHNEFRRLLLGNQMTSSTPLAQSLLIPNESIFSNIQEEQHQRELCVLRRRLEELENSQQQQLEELAAPLDRDRERLSSPRDALPDLS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0006996 (organelle organization), GO:0030030 (cell projection organization), GO:0022607 (cellular component assembly), GO:0044782 (cilium organization), GO:0070925 (organelle assembly), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0060271 (cilium assembly), GO:0120031 (plasma membrane bounded cell projection assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0005814 (centriole), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015630 (microtubule cytoskeleton)