lokahq/bioreason-rl huggingface dataset:
Protein: RCG49913 (A6K520)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR000372: Leucine-rich repeat N-terminal domain (domain) [28-377]
- IPR003591: Leucine-rich repeat, typical subtype (repeat) [89-518]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [29-581]
- IPR000483: Cysteine-rich flanking region, C-terminal (domain) [216-580]
- IPR001611: Leucine-rich repeat (repeat) [89-494]
Sequence:
MLSGVWFLSVFTVAGILQIESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRPGAFSGLKTLKRLHLNNNKLEVLREDTFLGLESLEYLQADYNYISTIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDLCPRKSASGDSSQRSSHSDTHVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVALTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYTSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDNPNLSDGTVLSMNHNTDTPRSLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRSATNLDVSSFQLQYGSYNTETNDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQDFSYGNLEEKKEEPATLAYTISATELLEKQATPKEPELLYQNIAERAKELPSAGLVHYNFCTLPKRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPDHPLLQAKPQSEPDYLEVLEKQTAISQL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0065008 (regulation of biological quality), GO:0071840 (cellular component organization or biogenesis), GO:0007155 (cell adhesion), GO:0050794 (regulation of cellular process), GO:0016043 (cellular component organization), GO:0050803 (regulation of synapse structure or activity), GO:0051128 (regulation of cellular component organization), GO:0098609 (cell-cell adhesion), GO:0044087 (regulation of cellular component biogenesis), GO:0098742 (cell-cell adhesion via plasma-membrane adhesion molecules), GO:0050807 (regulation of synapse organization), GO:0034330 (cell junction organization), GO:1901888 (regulation of cell junction assembly), GO:0050808 (synapse organization), GO:0051963 (regulation of synapse assembly), GO:0099174 (regulation of presynapse organization), GO:0099560 (synaptic membrane adhesion), GO:1905606 (regulation of presynapse assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0098794 (postsynapse), GO:0045211 (postsynaptic membrane), GO:0045202 (synapse), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0097060 (synaptic membrane)
Protein: BCL2-associated athanogene 4 (A6IW04)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR003103: BAG domain (domain) [379-456]
- IPR036533: BAG domain superfamily (homologous_superfamily) [371-457]
- IPR039773: Molecular chaperone regulator BAG (family) [375-454]
Sequence:
MSALRRSGYGPSDGPSYGRYYGPGGGDVPVHVPPPLYHPLRPEPPQPPVSWRGRGGAPAETTWPGEGAGGDGYYPSGGAWAEPSRAGGGHQEQPPYPGYNSNYWNSVRPRAPYPSTYPMRPELQGQSLNSYANGAYGPPYPPGPATASAASYSGAYYVPGYAQGTYSTDIPSTYRSPGNSPTPVSRWMYPQQDCPTEAPPLRGQVPGYPASQNPAMTLPHYPYGDGNRTVPQSGATGRPQDDAWASSAYGMGARYPWPSAAPSAPSGNLYMTESASPWPGNSSPQPPPSPPPQQPKDSSYSYSQSGQGMNRHSFPCSVRQYESPGAVNNDESDLLDSQVQYSAEPQLYGNTSSEHPSNQVPSNNLPEECFSSDEGTPPSIKKIIHVLEKVQYLEQEVEEFVGKKTDKAYWLLEEMLTKELLELDSVVTGGQDSVRQARKEAVCKIQAILEKLEKKGL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0009892 (negative regulation of metabolic process), GO:0019222 (regulation of metabolic process), GO:0048523 (negative regulation of cellular process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0051253 (negative regulation of RNA metabolic process), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:1903312 (negative regulation of mRNA metabolic process), GO:1903311 (regulation of mRNA metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: RCG63119 (A6KHY9)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR029063: S-adenosyl-L-methionine-dependent methyltransferase superfamily (homologous_superfamily) [116-366]
- IPR030373: Polyamine biosynthesis domain, conserved site (conserved_site) [194-207]
- IPR030374: Polyamine biosynthesis domain (domain) [122-362]
- IPR040900: Spermine synthase, N-terminal (domain) [21-117]
- IPR015576: Spermine synthase, animal (family) [1-365]
- IPR035246: Spermidine synthase, tetramerisation domain (domain) [123-172]
- IPR037163: Spermidine synthase, tetramerisation domain superfamily (homologous_superfamily) [117-172]
Sequence:
MAAARHSTLDFTLGAKADGEAILKGLQSIFQEQGMAESVHTWQDHGYLATYTNKNGSFANLRIYPHGLVLLDLQSYDSDVQGKQETDSLLNKIEEKMKELSQDSTGRVKRLPPIVRGGAIDRYWPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESDLAYTRAIMGNGKEDYTGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRRTCGDVLDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLYCPVEFSKEIVCVPSYLELWVFYTVWKKAKP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0009308 (amine metabolic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0006576 (biogenic amine metabolic process), GO:0009309 (amine biosynthetic process), GO:0042401 (biogenic amine biosynthetic process), GO:0006595 (polyamine metabolic process), GO:0006596 (polyamine biosynthetic process), GO:0008215 (spermine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Interleukin 9 receptor, isoform CRA_b (A6HDB8)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [140-252]
- IPR003961: Fibronectin type III (domain) [145-254]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [143-261]
- IPR003531: Short hematopoietin receptor, family 1, conserved site (conserved_site) [210-251]
Sequence:
MALGRCFPEGCTVEGAAVKQVSWFLIYSCVCSCVCWGVSVPAQEGGRKAGTFTCFSNSVFRIDCHWSAPEPGSRAWLLFTSNQVTDIKHKCTFWDSRCTLVLPKEEAFLPFDNFTITLHRCVMGQEQVSLVDSQYLPRRHIKLDPPSDLQSNVSSGRCVLTWGISFGLEPLITSLSYELAFKRQEEAWEQARLKDRIVGVTWLVLEAIELNPDTIYEARLRVQMALESYDDKTEGEYYKSHWSEWSQSVSFPSPRRKTQDLDRGPQSRTTSKTGWCQRSVGRLRVQHLGGHRHTHL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0005126 (cytokine receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0045927 (positive regulation of growth), GO:0048522 (positive regulation of cellular process), GO:0040008 (regulation of growth), GO:0050794 (regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0001558 (regulation of cell growth), GO:0030307 (positive regulation of cell growth)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009986 (cell surface)
Protein: Unc-84 homolog A (C. elegans), isoform CRA_c (A6K1X2)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR040994: SUN coiled coil domain 2 (domain) [553-611]
- IPR045119: SUN domain-containing protein 1-5 (family) [48-788]
- IPR032680: SUN domain-containing protein 1, N-terminal (domain) [66-292]
- IPR012919: SUN domain (domain) [628-789]
Sequence:
MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHRLEPVFDSPRMSRRSLRLITTTAAYSSGDGQTVDTHISTSRATPAKGRETRTVKQRSASKPAFSINHLSGKGLSSSTSHDSSCSLRSATVLRHPVLDESLIREQTKVDHFWGLDDDGDLKGGNKAATQGNGELAAEVASSNGYTCRDCRMLSARTDALTAHSAVHGPTSRVYSRDRTLRPRDLLVRALRRTRAAGWSVAEAMWSVLWLAVTAPGKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGFSLWGQGNFFSLLPMLNWTAMQPAQRVDNPKDMHRPGPLSPSPPLKVDPMASQWPQESDMGQKIASLSAQCHNHDERLAELTVLLQKLQIRVDQVDDGREGLSLWVKDMVGQHLQEIGSIEPPDAKTDFLTLHHDHEVRLSSLEDVLRKLTEKSEAIQKELEETKLRAGSRDEEQPLLDRVQHLELELNLLKSQLSDWQHLRSSCEQADARIQETVQLMFSEDQPGGSLEWLLQKLSSRFVSKDELQVLLHDLELKLLQNITHHITVTGQAPTSEAIVSAMSQAGISGITEAQAHIIVNNALRLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGVPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPRDFAVYGLETEYQEEGQPLGRFTYDQEGDSLQMFHTLERPDQGFQIVELRVLSNWGHPEYTCLYRFRVHGEPIQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005521 (lamin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0001503 (ossification), GO:0009612 (response to mechanical stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Histidine rich calcium binding protein, isoform CRA_b (A6JB08)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR015666: Sarcoplasmic reticulum histidine-rich calcium-binding protein (family) [1-754]
- IPR019552: Histidine-rich calcium-binding (repeat) [211-473]
Sequence:
MGFQEPWLYSCLLWATVAILLVPPVVTQELRGTGLGLGNWNNNAGIPGSSEDLSTEYGHHIHSHGAYQGEKDRHHREEDEDFSREYGHQVQDHRYPGHEVGEENVSEEVFRGHVRQLHGHHKPNSEDLGDSAESHFPRQQSHNREEEDGVVSGEDHRHIPRHDHHGNEEEDDDGEEEERVGVMENSDDKHQAHGHHSHSKERDGLHHAHSHRHQGHHDEDDDDEDGVSTEGEHQAHRYQDHDEEDDDDSDEESHAHRLQGQEDENDDEDGDSSENGHQTQDHQGHKEQDDDDDEEEEEEEEEEEEEEEEEEEEEEDDDDDSTEHRHRHQTQGHRKGKDEDESDEDDHVTRHGRRGHEDEDDDDDDDDDDDDDNDGGSTENVHQAHRHRGHEHEDDGDDSEEDYHHVPSHGHQSHQNEEEEDEAVSTEHWHQSPRHAHHDLGRENQEEATVKYSRHVASHRPQGHSAEEDSLEDSTNEVPGHHHHRVSRDGDEDISTEFGHKAPRHRLQDQDEWTRQGHGKSVQEDIGHQPLQPTGPGSGESRKEDDHSSQEGDEDLKQRQEAHSEEEEEEEEGHGLPMSLEDEEEEEKDKKESKGDRAAVSAPLSHHRKHDDDDDGDGDDDDDDNDDDDEILEENLLPFTIIPNPLAGREVAREGSSEEESREVTGQQDAQEYENYQPGSLCGYCSFCNRCSECESCHCDEENMGEHCDQCQHCQFCYLCPLVCDTLCTPGSYVDYFSSSVYQAVADMLETQEP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0044325 (transmembrane transporter binding), GO:0019899 (enzyme binding), GO:0051117 (ATPase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0065008 (regulation of biological quality), GO:0050794 (regulation of cellular process), GO:0051051 (negative regulation of transport), GO:0048523 (negative regulation of cellular process), GO:0032879 (regulation of localization), GO:0051049 (regulation of transport), GO:0060341 (regulation of cellular localization), GO:0032387 (negative regulation of intracellular transport), GO:0051481 (negative regulation of cytosolic calcium ion concentration), GO:0043271 (negative regulation of monoatomic ion transport), GO:0051926 (negative regulation of calcium ion transport), GO:0032386 (regulation of intracellular transport), GO:0043269 (regulation of monoatomic ion transport), GO:0010959 (regulation of metal ion transport), GO:0051924 (regulation of calcium ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0099080 (supramolecular complex), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0099081 (supramolecular polymer), GO:0099512 (supramolecular fiber), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0099513 (polymeric cytoskeletal fiber), GO:0005874 (microtubule), GO:0015630 (microtubule cytoskeleton)
Protein: Large ribosomal subunit protein eL33 (A0A8L2QQD7)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR018266: Large ribosomal subunit protein eL33, conserved site (conserved_site) [72-93]
- IPR038661: Large ribosomal subunit protein eL33 superfamily (homologous_superfamily) [1-110]
- IPR001780: Large ribosomal subunit protein eL33 (family) [4-110]
- IPR009000: Translation protein, beta-barrel domain superfamily (homologous_superfamily) [5-104]
Sequence:
MSGRLWCKAIFAGYKRGLRNQRERMALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGEPNKTRVIWGKVTRAHGNSGRVCAKFRSNLPAKAIGHRIHVMLYPSRI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0043021 (ribonucleoprotein complex binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0051716 (cellular response to stimulus), GO:0070887 (cellular response to chemical stimulus), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0071495 (cellular response to endogenous stimulus), GO:1901700 (response to oxygen-containing compound), GO:0031099 (regeneration), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0031100 (animal organ regeneration), GO:0032870 (cellular response to hormone stimulus), GO:1901654 (response to ketone), GO:0071310 (cellular response to organic substance), GO:0033993 (response to lipid), GO:0048732 (gland development), GO:0048545 (response to steroid hormone), GO:0014070 (response to organic cyclic compound), GO:1901701 (cellular response to oxygen-containing compound), GO:0061008 (hepaticobiliary system development), GO:1901655 (cellular response to ketone), GO:0071548 (response to dexamethasone), GO:0001889 (liver development), GO:0071383 (cellular response to steroid hormone stimulus), GO:0031960 (response to corticosteroid), GO:0097421 (liver regeneration), GO:0071407 (cellular response to organic cyclic compound), GO:0071396 (cellular response to lipid), GO:0071549 (cellular response to dexamethasone stimulus), GO:0051384 (response to glucocorticoid), GO:0071384 (cellular response to corticosteroid stimulus), GO:0071385 (cellular response to glucocorticoid stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0044391 (ribosomal subunit), GO:0043229 (intracellular organelle), GO:0022626 (cytosolic ribosome), GO:0043228 (non-membrane-bounded organelle), GO:0015934 (large ribosomal subunit), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0022625 (cytosolic large ribosomal subunit), GO:0005840 (ribosome)
Protein: Xeroderma pigmentosum, complementation group A (Predicted), isoform CRA_a (A6IJB2)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR037129: XPA domain superfamily (homologous_superfamily) [98-208]
- IPR022656: XPA, C-terminal (domain) [135-186]
- IPR022658: XPA, conserved site (conserved_site) [138-154]
- IPR022652: Zinc finger, XPA-type, conserved site (conserved_site) [103-133]
- IPR000465: XPA/RAD14 (family) [17-224]
- IPR009061: Putative DNA-binding domain superfamily (homologous_superfamily) [134-207]
Sequence:
MATAEEKRTSPEPAAAEKPAELPAAVRASVERKRQRALMLRQARLAARPYPAAAATGGVTSIKAAPKVIDTKGGFILEEEEEEKHKIGDVVHEPGPVMEFDYTICEECGKEFMDSYLMNHFDLPTCDSCRDADDKHKLITKTEAKQEYLLKDCDLEKREPALRFIVKKNPRHSQWGDMKLYLKLQVVKRALEVWGSQEALEDAKEVRQENREKMKQKKFDKKVKVGFYDAMKILLYDKPLY
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003684 (damaged DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0009612 (response to mechanical stimulus), GO:0010996 (response to auditory stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Receptor (TNFRSF)-interacting serine-threonine kinase 1 (Predicted) (A6J7H3)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR011029: Death-like domain superfamily (homologous_superfamily) [555-658]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [134-146]
- IPR001245: Serine-threonine/tyrosine-protein kinase, catalytic domain (domain) [21-284]
- IPR051681: Serine/Threonine Kinases and Pseudokinases (family) [18-281]
- IPR000719: Protein kinase domain (domain) [17-289]
- IPR025735: RIP homotypic interaction motif (binding_site) [523-538]
- IPR037934: RIP1, Death domain (domain) [570-655]
- IPR000488: Death domain (domain) [560-656]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [6-296]
Sequence:
MQPDMSLDNIKMASDDLLERKDLDSGGFGKVSLCFHRTHGFVILKKVYTGPNRAEYNEALLEEGKMMHRLRHDRVVKLLGIIIEEGNYSLVMEYMEQGNLMHVLKTKESVPLSVKGRIIVEIIEGMHYLHDEGVIHKDLKPENILVDRDFHIKIADLGVASFKTWSKLTKEEHNKQREASSVTKKNGGTLYYMAPEHLTDINTKPTEKSDVYSFAIVLWAIFANKEPYENVICTEQFLVCINSGNRPNVEDILEFCPREIISLMERCWQTNPEDRPTFFGIEKEFKPFYLSQFEEYVEEDVASLKKEYPSQSPVLKRMFSLQHDCVPLPPSRSNSEQPGSLHSSQGLPMGPVEESWFSSSPEYPQEENERSVQAKLQEEASYHAFGIFAEKQTKSQPRLNEAYNREEERKRRVSHDPFAQQRVHENVKSAGAKGLPYPSTTSHGNAAHQLSGPASQIKVPLWNNGVYNHHGFGATGTGVWYGPSVSQSYNAYKTPVPETNLPGSIPTMPYISLAPPDDSIRCTIYNSSRVQIGNYNYMDLGPSSQPPTNTCKVESTSRHQAVFANTTSLTDKHLNPIRENMGKQWKNCARKLGFTESQIDEIDHDYERDGLKEKVYQMLQKWLMREGTKGATVGKLAQALHQCCRTDLLNQLIQASQS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0005126 (cytokine receptor binding), GO:0032813 (tumor necrosis factor receptor superfamily binding), GO:0005123 (death receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0010942 (positive regulation of cell death), GO:0010941 (regulation of cell death), GO:0043067 (regulation of programmed cell death), GO:0043068 (positive regulation of programmed cell death), GO:0010939 (regulation of necrotic cell death), GO:0010940 (positive regulation of necrotic cell death), GO:0062098 (regulation of programmed necrotic cell death), GO:0060544 (regulation of necroptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0016020 (membrane), GO:0098857 (membrane microdomain), GO:0045121 (membrane raft)