Protein: Filamin A (A6KRS3)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR001298: Filamin/ABP280 repeat (repeat) [280-2639]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [278-2638]
- IPR036872: CH domain superfamily (homologous_superfamily) [26-277]
- IPR001589: Actinin-type actin-binding domain, conserved site (conserved_site) [45-145]
- IPR017868: Filamin/ABP280 repeat-like (repeat) [276-2638]
- IPR014756: Immunoglobulin E-set (homologous_superfamily) [279-2638]
- IPR044801: Filamin family (family) [1663-2620]
- IPR001715: Calponin homology domain (domain) [43-269]
Sequence:
MSSSHSRSGQSAAGASPAGGIDTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGIGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPTACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKGEERVKQKDLGDGVYGFEYYPTIPGTYTVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGIVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVKARGPGLEKTGVAINKPAEFTVDAKHAGKAPLRVQVQDNEGHSVETTVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCTEAGQGDVSIGIKCAPGVVGPTEADIDFDIIRNDNDTFTVKYTPCGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLNRTGVELGKPTHFTVNAKTAGKGKLDVQFSGLAKGDAVRDVDIIDHHDNTYTVKYTPVQQGPVGVSVTYGGDHIPKSPFSVGVSPSLDLSKIKVSGLVDKVDVGKDQEFTVKSKGAGGQGKVASKIVSPSGAAVPCKVEPGLGADNSVVRFVPREEGPYEVEVTYDGVPVPGSPFPVEAVAPTKPSKVKAFGPGLQGGNAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQDCGDGTYKVEYTPYEEGVHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGSYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPTVQTPLRPQQLPSQYTYPQGSQQTWIPERPMVGVNGLDVTSLRPFDLVIPFTIKKGEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAPSVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFGIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGPGPADVSKVVAKGLGLSKAYVGQKSNFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMVP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0046332 (SMAD binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0051641 (cellular localization), GO:0048856 (anatomical structure development), GO:0009058 (biosynthetic process), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0003006 (developmental process involved in reproduction), GO:0033036 (macromolecule localization), GO:0044237 (cellular metabolic process), GO:0040017 (positive regulation of locomotion), GO:0050794 (regulation of cellular process), GO:0044238 (primary metabolic process), GO:0040012 (regulation of locomotion), GO:0048522 (positive regulation of cellular process), GO:0021987 (cerebral cortex development), GO:1901576 (organic substance biosynthetic process), GO:2000145 (regulation of cell motility), GO:0048468 (cell development), GO:0021537 (telencephalon development), GO:0046483 (heterocycle metabolic process), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0030902 (hindbrain development), GO:0044249 (cellular biosynthetic process), GO:0048608 (reproductive structure development), GO:0045137 (development of primary sexual characteristics), GO:0051130 (positive regulation of cellular component organization), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0032970 (regulation of actin filament-based process), GO:0044089 (positive regulation of cellular component biogenesis), GO:0043170 (macromolecule metabolic process), GO:2000147 (positive regulation of cell motility), GO:0044087 (regulation of cellular component biogenesis), GO:0000902 (cell morphogenesis), GO:1901360 (organic cyclic compound metabolic process), GO:0042127 (regulation of cell population proliferation), GO:0060009 (Sertoli cell development), GO:0006139 (nucleobase-containing compound metabolic process), GO:0009888 (tissue development), GO:0060322 (head development), GO:0030900 (forebrain development), GO:0021543 (pallium development), GO:0070727 (cellular macromolecule localization), GO:0007548 (sex differentiation), GO:0060008 (Sertoli cell differentiation), GO:0046661 (male sex differentiation), GO:0051128 (regulation of cellular component organization), GO:0008284 (positive regulation of cell population proliferation), GO:0016477 (cell migration), GO:0009059 (macromolecule biosynthetic process), GO:0061458 (reproductive system development), GO:1901362 (organic cyclic compound biosynthetic process), GO:0019438 (aromatic compound biosynthetic process), GO:2000179 (positive regulation of neural precursor cell proliferation), GO:0008406 (gonad development), GO:0046546 (development of primary male sexual characteristics), GO:0032956 (regulation of actin cytoskeleton organization), GO:0021535 (cell migration in hindbrain), GO:0030334 (regulation of cell migration), GO:0030855 (epithelial cell differentiation), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:2000177 (regulation of neural precursor cell proliferation), GO:0007420 (brain development), GO:1902903 (regulation of supramolecular fiber organization), GO:0032233 (positive regulation of actin filament bundle assembly), GO:0000904 (cell morphogenesis involved in differentiation), GO:0007399 (nervous system development), GO:0090304 (nucleic acid metabolic process), GO:0002064 (epithelial cell development), GO:0032231 (regulation of actin filament bundle assembly), GO:1902905 (positive regulation of supramolecular fiber organization), GO:0018130 (heterocycle biosynthetic process), GO:0030335 (positive regulation of cell migration), GO:0033043 (regulation of organelle organization), GO:0007417 (central nervous system development), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0008104 (protein localization), GO:0060429 (epithelium development), GO:0010638 (positive regulation of organelle organization), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0051493 (regulation of cytoskeleton organization), GO:1902414 (protein localization to cell junction), GO:0008584 (male gonad development), GO:2001224 (positive regulation of neuron migration), GO:2001222 (regulation of neuron migration), GO:0110053 (regulation of actin filament organization), GO:0032774 (RNA biosynthetic process), GO:0097659 (nucleic acid-templated transcription), GO:0051495 (positive regulation of cytoskeleton organization), GO:0150105 (protein localization to cell-cell junction), GO:0016071 (mRNA metabolic process), GO:0006351 (DNA-templated transcription), GO:0009299 (mRNA transcription), GO:0006366 (transcription by RNA polymerase II), GO:0042789 (mRNA transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0044297 (cell body), GO:0005829 (cytosol), GO:0048471 (perinuclear region of cytoplasm), GO:0071944 (cell periphery), GO:0030054 (cell junction), GO:0043198 (dendritic shaft), GO:0098794 (postsynapse), GO:0036477 (somatodendritic compartment), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0005938 (cell cortex), GO:0043228 (non-membrane-bounded organelle), GO:0099081 (supramolecular polymer), GO:0043025 (neuronal cell body), GO:0097447 (dendritic tree), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0098978 (glutamatergic synapse), GO:0030425 (dendrite), GO:0030863 (cortical cytoskeleton), GO:0043005 (neuron projection), GO:0099512 (supramolecular fiber), GO:0099513 (polymeric cytoskeletal fiber), GO:0097440 (apical dendrite), GO:0005634 (nucleus), GO:0005856 (cytoskeleton), GO:0015629 (actin cytoskeleton), GO:0005884 (actin filament)