Protein: Solute carrier family 12 member 1 (A0A8M9PFN1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
- IPR013612: Amino acid permease, N-terminal (domain) [36-94]
- IPR004842: SLC12A transporter family (family) [46-1037]
- IPR002443: Solute carrier family 12 member 1/2 (family) [183-585]
- IPR018491: SLC12A transporter, C-terminal (domain) [639-1037]
- IPR004841: Amino acid permease/ SLC12A domain (domain) [127-630]
Sequence:
MENPGFQTSKDDPPQYEETSFCTNGFGNGERRAIRSSVVSAFGHDTLDRVPNPDFYRNAASISGHRAVRPSLHELHDVFQKNGGLNLPSPVEDSEGVDSSTLGDVESVTPLEEKDTGGVVKFGWIKGVLVRCMLNIWGVMLFIRLSWVFGQAGIGLGIVVVLLSMVVTSVTCLSMSAICTNGVVRGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVVELLKDSNALIVDPTNDIRIIGCITVVLLMGITVAGMEWEAKAQVALLVILLVAIANVFVGTVIPSTQDKRSKGFFNYHESIAKENFIPDFRDGETFFSVFAIFFPAATGILAGANISGDLRDPQGALPKGTLLAIFITGVTYLGIALVVSVTVVRDATGNRNDTIQAGASCNFSSACDFGYDFSICQTTKCNYGLMNNFQVMTLVSGFGPLITAGTFSATLSSALASLVSAPKVFQALCKDNIYKALKFFAKGHGKNNEPIRGYVLTFIIAVAFILIAQLNTIAPIISNFFLASYALINYSCFHASYAKSPGWRPAYKYYNMWLSLFGAVLCCAVMFVINWWAALLTYGIEFFLYIYVTVKKPDVNWGSSTQAVTFINAVNNALILSGVDDHIKNFRPKCLVLTGSPRSRPALLDLSHSFTKNYGLCLTCEVFVGSRDKNLQDMIEGDVQNQLWLNKQKHKAFYTPIASDTLRDGAQALMQASGLGRMKPNTVMLGFKRDWRTSKPQDVQNYVGILHDTFDFELGTVIMRVSQGMDISHILKAEEEMERMILEQQALEMEENDFQPGPRGFFNRAKKTPKKEPTSKVSLGVPQASDLAKLNQRLVEASGQFKQQQGKGNIDVWWLFDDGGLTLLLPHILTTRKKWRECRLRIFIAGQPERIQQDKEEMQLLLKKFRIKCEDIKVISDLNIRPSAENWKLFEDMIEPFRLHEGSKDSSQTEALRKEQPWKITDAELDAFEQKTMLQVRLNELLQESSRAAKLIVVSLPIARKGSVSDHLYMAWLEALTKNLPPTLLIRGNHKSVLTIYS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0008509 (monoatomic anion transmembrane transporter activity), GO:0015079 (potassium ion transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0015103 (inorganic anion transmembrane transporter activity), GO:0015108 (chloride transmembrane transporter activity), GO:0022853 (active monoatomic ion transmembrane transporter activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0015081 (sodium ion transmembrane transporter activity), GO:0015291 (secondary active transmembrane transporter activity), GO:0015296 (monoatomic anion:monoatomic cation symporter activity), GO:0015293 (symporter activity), GO:0015379 (potassium:chloride symporter activity), GO:0015294 (solute:monoatomic cation symporter activity), GO:0046873 (metal ion transmembrane transporter activity), GO:0015370 (solute:sodium symporter activity), GO:0015377 (chloride:monoatomic cation symporter activity), GO:0015378 (sodium:chloride symporter activity), GO:0015373 (monoatomic anion:sodium symporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0035295 (tube development), GO:0009887 (animal organ morphogenesis), GO:0048729 (tissue morphogenesis), GO:0009888 (tissue development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0035239 (tube morphogenesis), GO:0072001 (renal system development), GO:0060562 (epithelial tube morphogenesis), GO:0055123 (digestive system development), GO:0072176 (nephric duct development), GO:0001655 (urogenital system development), GO:0002009 (morphogenesis of an epithelium), GO:0060429 (epithelium development), GO:0001822 (kidney development), GO:0048546 (digestive tract morphogenesis), GO:0048565 (digestive tract development), GO:0060993 (kidney morphogenesis), GO:0072114 (pronephros morphogenesis), GO:0048793 (pronephros development), GO:0072178 (nephric duct morphogenesis), GO:0072073 (kidney epithelium development), GO:0039022 (pronephric duct development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0045177 (apical part of cell), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0016324 (apical plasma membrane)