Protein: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100, isoform CRA_a (A6JHL7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm. Nucleus
InterPro domains:
- IPR011029: Death-like domain superfamily (homologous_superfamily) [760-848]
- IPR030497: Nuclear factor NF-kappa-B, p100 subunit, RHD domain, N-terminal (domain) [38-221]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [225-341]
- IPR032397: Rel homology dimerisation domain (domain) [229-327]
- IPR037059: Rel homology domain (RHD), DNA-binding domain superfamily (homologous_superfamily) [37-221]
- IPR030492: Rel homology domain, conserved site (conserved_site) [53-59]
- IPR002110: Ankyrin repeat (repeat) [486-698]
- IPR000451: NF-kappa-B/Dorsal (family) [24-874]
- IPR036770: Ankyrin repeat-containing domain superfamily (homologous_superfamily) [479-752]
- IPR011539: Rel homology domain, DNA-binding domain (domain) [35-224]
- IPR014756: Immunoglobulin E-set (homologous_superfamily) [226-358]
- IPR002909: IPT domain (domain) [227-326]
- IPR008967: p53-like transcription factor, DNA-binding domain superfamily (homologous_superfamily) [37-230]
- IPR000488: Death domain (domain) [763-850]
- IPR033926: NFkappaB IPT domain (domain) [228-327]
Sequence:
MDRCYDPGLDGIPEYDDFEFSPSIVEPKDPAPETADGPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGVCAVSVGPKDMTAQFNNLGVLHVTKKNMMEIMIQKLQRQRLRSKPQGLTEAERRELEQEAKELKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSVRGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGSGGSAGGYGGAGGGGSLGFFSSFAYSPYQSGAAPMGCFPGGGGGAQMAGSGRDAEAGEAEEQPRAPSEAPQSEQQALDTLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHLLMAQDENGDTPLHLAIIHGQTGVIEQIAQVIYHAQYLGVINLTNHLHQTPLHLAVITGQTRVVSFLLQVGADPTLLDRHGDSAVHLALRAGAAAPDLLQAVLHSGAHALPQMLHMPDFEGLYPVHLAVHARSPECLDLLVDCGAEVEAAERQGGRTPLHLATEMEELGLVTHLVTKLHANVNARTFAGNTPLHLAAGLGSPTLTRLLLKAGADIHAENEEPLCPLPSPPTSGSDSDSEGPETDTQRNFRGHTPLDLTRSTKVKTLLLNAAQNTTEPPLAPPSPAGPGLSLGDAALQNLEQLLDGPEAQGSWAELAERLGLRSLVDTYRKTPSPSGSLLRSYKLAGGDLVGLLEALSDMGLHEGVRLLKAPETRDKLPSTEVKEDSAYGSQSVEQEAEKLCPPPEPPGGLCHGHPQPQVH
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:0007568 (aging), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:1901700 (response to oxygen-containing compound), GO:0043207 (response to external biotic stimulus), GO:0010033 (response to organic substance), GO:0009617 (response to bacterium), GO:0002237 (response to molecule of bacterial origin), GO:0034097 (response to cytokine), GO:0032496 (response to lipopolysaccharide), GO:0033993 (response to lipid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)