Protein: Homeodomain-interacting protein kinase 2 isoform X3 (A0A8M2B5G0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [341-353]
- IPR000719: Protein kinase domain (domain) [220-548]
- IPR050494: Serine/threonine and dual-specificity kinase (family) [138-549]
- IPR017441: Protein kinase, ATP binding site (binding_site) [226-249]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [211-558]
Sequence:
MAPVYEGMASQVQVFSPHTLQSSAFFSVKKLKVEQSCNWDMTGYGTHSKVYSQNSKQSVSVAPVGINGASLQVSNSSLSYEQALLFPAGSGHIVVASASSTSGAAGQLLGSTGSSGSGSGGHNLTRRSTVSLLDTYQRCGLKRKSEELDNNNGSGSGSSVHVVEEQQPPAPMIQNNVQSGATVATATASTTATSKNSGANSEGDYQLLQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTSEIVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPARQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDPDSTYPLWRLKTPEDHEAETGIKSKEARKYIFNCLDDMAQVNMTTDLEGSDMLAEKADRREFIDLLTKMLTIDADKRITPIETLNHPFVTMTHLLDFPHSTHVKSCFQNMEICKRRVNMYDTVNQSKTPFITHVAPSTSTNLTMTFNNQLNTVHSQPSAAPMAAVAPRTMPLQPGAPQLCAARPDPFQQALIVCPPGFQGLQASPSKHTGYSVRMENAVPIVTQAPGAQPLQIQPGLLTQQAWPSGTQQILLPPAWQQLTHTSVQHATVIPDSMTSSQPLANWRNSHPHGSHYNPIMQQPALLAGHVTLPPQQPLNVGVAHVMRQPSNNQSNSKKNKQHQMNNRNVSGYDVSSTQPVTSPQRSKRVKENTPPRCAVVQNGPPSTCVPSQTCTGGGWGGEQACSTTRDHHGQHNPPRQTIIIPDTPSPAVSIITISSDTDEEDDLKQPTNTSTSSKQRKNVISCVTVHDSPDSDSSNTSPYAVDSRTNGPNANGYDSKGAVLDNYSNGNPRTIIIPPLKSQTSENLGECDRLLPDVMNHQNSTYKFKTSNGGFSGNNHTSGGVTGGGAYRQQRTGPHPFQQQPLNLSQAQQHMAVERNGGHRRQQAYITPTMATQAQYSFHNSPTHTANVHPHLAAPHLPGQPHLYTYTAPAALGSTGTVAHLVASQGSARHAVQHASYPPGIVHQVPVSMGHRVLPSPTLHHGQYQAQFAHQTYISASPVYTGYPLSPTKMNQYPYL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0036094 (small molecule binding), GO:0016740 (transferase activity), GO:1901363 (heterocyclic compound binding), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0140096 (catalytic activity, acting on a protein), GO:0097367 (carbohydrate derivative binding), GO:1901265 (nucleoside phosphate binding), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0004672 (protein kinase activity), GO:0043168 (anion binding), GO:0000166 (nucleotide binding), GO:0032553 (ribonucleotide binding), GO:0035639 (purine ribonucleoside triphosphate binding), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0032555 (purine ribonucleotide binding), GO:0017076 (purine nucleotide binding), GO:0005524 (ATP binding), GO:0032559 (adenyl ribonucleotide binding), GO:0030554 (adenyl nucleotide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050793 (regulation of developmental process), GO:0048856 (anatomical structure development), GO:0009653 (anatomical structure morphogenesis), GO:0050794 (regulation of cellular process), GO:0009888 (tissue development), GO:0045595 (regulation of cell differentiation), GO:0048729 (tissue morphogenesis), GO:0060429 (epithelium development), GO:0002009 (morphogenesis of an epithelium), GO:0060026 (convergent extension)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)