Protein: Pyruvate kinase (A0A804F729)
Organism: Homo sapiens (Human)
InterPro domains:
- IPR011037: Pyruvate kinase-like, insert domain superfamily (homologous_superfamily) [191-292]
- IPR015806: Pyruvate kinase, insert domain superfamily (homologous_superfamily) [191-293]
- IPR018209: Pyruvate kinase, active site (active_site) [339-351]
- IPR015795: Pyruvate kinase, C-terminal (domain) [484-602]
- IPR015793: Pyruvate kinase, barrel (domain) [117-449]
- IPR040442: Pyruvate kinase-like domain superfamily (homologous_superfamily) [120-459]
- IPR001697: Pyruvate kinase (family) [88-604]
- IPR036918: Pyruvate kinase, C-terminal domain superfamily (homologous_superfamily) [73-604]
- IPR015813: Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily (homologous_superfamily) [89-468]
Sequence:
MQWSSERGERLLTPGACSSEVPSAVPSRSGGSPGHTVFSSERSLLVRPRSHPEPKGEHYVTGSPTPENQRTSAAMSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELVRASSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140110 (transcription regulator activity), GO:1901363 (heterocyclic compound binding), GO:0016740 (transferase activity), GO:0044877 (protein-containing complex binding), GO:0097159 (organic cyclic compound binding), GO:0003712 (transcription coregulator activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0023023 (MHC protein complex binding), GO:0046983 (protein dimerization activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0004672 (protein kinase activity), GO:0042802 (identical protein binding), GO:0050839 (cell adhesion molecule binding), GO:0003713 (transcription coactivator activity), GO:0035173 (histone kinase activity), GO:0045296 (cadherin binding), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity), GO:0042803 (protein homodimerization activity), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0003723 (RNA binding), GO:0004713 (protein tyrosine kinase activity), GO:0004743 (pyruvate kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0050793 (regulation of developmental process), GO:0048522 (positive regulation of cellular process), GO:0019222 (regulation of metabolic process), GO:0051240 (positive regulation of multicellular organismal process), GO:0008219 (cell death), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0051239 (regulation of multicellular organismal process), GO:0051094 (positive regulation of developmental process), GO:0012501 (programmed cell death), GO:1904018 (positive regulation of vasculature development), GO:2000026 (regulation of multicellular organismal development), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009891 (positive regulation of biosynthetic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:1901342 (regulation of vasculature development), GO:0031326 (regulation of cellular biosynthetic process), GO:0045766 (positive regulation of angiogenesis), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0045765 (regulation of angiogenesis), GO:0051252 (regulation of RNA metabolic process), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0010468 (regulation of gene expression), GO:1903670 (regulation of sprouting angiogenesis), GO:1902680 (positive regulation of RNA biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903672 (positive regulation of sprouting angiogenesis), GO:0006357 (regulation of transcription by RNA polymerase II), GO:0045893 (positive regulation of DNA-templated transcription), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0045944 (positive regulation of transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)