lokahq/bioreason-rl huggingface dataset:
Protein: Uncharacterized protein si:ch211-93f2.1 (A0A8M9PZ17)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [24-1608]
- IPR002018: Carboxylesterase, type B (domain) [28-1592]
- IPR019826: Carboxylesterase type B, active site (active_site) [211-1279]
- IPR019819: Carboxylesterase type B, conserved site (conserved_site) [117-1179]
Sequence:
MAMRESAVLSLCILIAVTLQNSVKAEDGPILQTNSGALKGLQMKARGKDTVIHSYLGIPFAKPPVGPLRLAPPQPAEKWEGVRDATKQPLMCLQDRQLVEDLVANLSAKVDMVDSSEDCLYLNVYTPSKPGRNDKLPVMVWIHGGGFTTCSASLFDGHVLAAYQDVVVVVIQYRLGLLGFFSTGDENAPGNYGLLDQVAALQWVQENIHSFGGDPGSVTIFGESAGGISVSLHVLSPLSANLFHRAIAESGTAAMEAIMNVNPLPIAQAIGNASGCDISSTKKIVDCLMQKSEVEILKITMENPLFRFGVTIDGQFLPRPAAELFQSQQFNKVPLMTGVTDDEIGFVLPNYLLPPDWINGLDLESILPLLTVFNPALQDQSVLELLLNEYLGTSPDRIRIRDGFREMLGDFMFNIPARQTASYHRDAGAPVYVYEFRHPPSVLQRKRPSFSGSDHGDEIVFVFGYCFSEGPIGMAENLSDEEDELCRTTMAYWGNFAHTGNPNGPGLTSWPEFGDEAEYLSIGLDPKASTDLKGKHFTFVTQTFPRILSERKEGPVVNTKLGSLRGSYMMAKGKDSVISSYFAIPFAKSPVGPLRLTPPQPADAWQGVRDATKQPPMCLQPKEVMVDLLATMPLKTEFPEVSEDCLYLNIYTPSKPGDNKKLPVMVWIHGGGLAFGSASIFDAHALAAYQDIVVVMVQYRLGLLGFFSTGDEHAPGNYGLLDQVAALQWVQENIHSFGGDPGSVTVFGESAGGVSASLLVLSPLSANLFHRAIAESGTAAMNAIMSPDPLSTARSLGNVSGCDISSTKKIVDCVMQMTEEDILKIAREQVLLRFGVTVDGQFLPKSVDELLQSQEFSKVPLMTGVTDDDGGFTLPEFIAPPGWRDGMTKDQIMPFLPTYNYDLQDPGLAEIVLKEYLGATTDKIKIRDGFREIVGDFFFNLPARKLANYHRDTGAPVYMYEFQHPAYIFQNKRPSFVGCDHGDELLFVFGYCFGNGHIKVEGELSKEEQELCKTTMAYWGNFARTGNPNGPGLVEWPKYGAEAEYLGIGLEQKSSKNFKGNHFHFMIEKLPQIIKEWKEGPVVETKLGSLRGAFLTVKGKDTIVNSYLGVPFAKPPVGPLRLARPQAAEKWQGVRDATKQPRMCLQERQMTVTELEFLSMDVEVPEVSEDCLYLNIYTPVKPGQGDKKLPVMVWIHGGGLSLGSASMYDGSVLAAYQDVVVVLIQYRLGLLGFLSTGDEHAPGNYGFLDQVAALQWVQENIHSFGGDPGSVTIFGESAGGISVSTLILSPLASGLFHRAIAESGTAFWDGLVMADPFQRAQTAAKQCNCDSSSSAKIVDCIMHWSEEEALECAKKFQMMHFSVAVDSYFLPKPIEEIVEKQEFSKVPLINGINNDEFGFLLAEYFLGPEWMNGLKREQIAEALTLTYPDPKDRWIIDLVAKEYLGDTHDPIEIREVYREMMGDVLFNIPALQLAKHHSGTGAPVYLYELQHPPSFLQKKRPSFVGVDHADDLYFIQGTCFAKAHLRISAPFTEEENELCRTVMAYWGNFAHTGSPNGPGLTHWPEYENENEYLAIGLQQKPGKNLKHKHYEFMTKTLPELIRQGKTKHSEL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0052689 (carboxylic ester hydrolase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:0033993 (response to lipid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0043227 (membrane-bounded organelle), GO:0120025 (plasma membrane bounded cell projection), GO:0005929 (cilium), GO:0031514 (motile cilium)
Protein: Calpain-3 (A0A8M9PSG7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Calcium-regulated non-lysosomal thiol-protease
Subcellular location: Cytoplasm. Nucleus, nucleolus
InterPro domains:
Sequence:
MAEEQKFSETSVQLTEAAPQTVGSGFTAPGNIYSAILSRNEAVKDARRLKDFQELRDKYVRKKVLFEDPLFPAQDSSLFYSEKFPLKLEWKRPMEICKNPQFILGGANRTDICQGDLGDCWLLAAIACLTLNDVILKRVVPHDQSFTENYAGIFHFQFWRYGEWVDVVIDDRLPTYKNKLVFTRSGQNNEFWSALMEKAYAKLHGSYEALKGGNSLEAMEDFTGGVTEFYEITEAPKELYNIMRKALKRGSLMGCAIDTLVPTAQRTKTASGLVRGHAYSVTGVEQGKRKDGKDLMIRLVRVRDPWGVAPPPACKSNDWVELAKTEQDKQRLQPGEQGEFWMCFEEFQKNFTKLEICNLTPDTLEDDQMFKWNVTVHEGRWVKGCSAGGCRNFPDTYWTNPQFRLVLLEADAKEKTCTVVVALMQKGRRVERCSGATLHNIGFAIYEVPKEMKGNQQQQLSKDFFLYNASTARSKSYVNIREVTERFCLKPGEYVIIPSTFDPHKESEFLLRVFSENRSTSKVIDAEIEAEPMVDNVKKKIKPFEEEETEEEKQFRAIFQQIAGDDMEINANELRTVLNRVVAKHKELKTEGFSLESCRSMIALLDTDGTGHLNLQEFKHLWNKIKQWKLVFTRFDTDKSSTISSFEMRNALTEAGFQLNNQLYDIICMRYANEHMELDFDSYISCLVRLEGMFRAFRAFDKDGDGLIKLNVFEWLQLTMYA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008234 (cysteine-type peptidase activity), GO:0004175 (endopeptidase activity), GO:0004197 (cysteine-type endopeptidase activity), GO:0004198 (calcium-dependent cysteine-type endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0006508 (proteolysis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0005773 (vacuole), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0005764 (lysosome)
Protein: Macrophage receptor MARCO isoform X1 (A0A8M2BH24)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Single- pass type II membrane protein
InterPro domains:
- IPR001190: SRCR domain (domain) [439-536]
- IPR050938: Collagen and Collagen-like Structural Proteins (family) [67-436]
- IPR008160: Collagen triple helix repeat (repeat) [142-436]
- IPR036772: SRCR-like domain superfamily (homologous_superfamily) [436-536]
Sequence:
METEVDDFPGKASIFSQVNPLYSNNMKLCEAERYDFQHSEPKTMKSASKRHCVPVLILLFLLLIGLNSFLAYKVFTLEAWVHTHCTSAQNHELTSASSFQLGSSKNEVECFTDLCGTDGTLEHLRTQINQLNATAEKAIVCPPGPPGPPGSNGIPGFPGQKGIPGSPGRVGEPGAPGQKGQTGDPGIKGERGMVGFPGIPGAPGRKGDSGERGLQGLPGNDGSPGQDGRTGPQGMPGPSGSQGVKGDPGLKGERGDQGPPGPTGPQGSSGARGLQGIPGEKGSPGPKGDTGVGLQGPTGQQGQKGSQGVPGVPGARGANGEKGDRGLSGVKGDPGLKGERGDQGQPGPTGPQGSSGARGLQGIPGGKGSPGPKGDTGVGLRGLTGQQGQKGSQGLPGVPGARGANGEKGDRGLSGQKGDQGPKGEKGDAGAKGASGGSQVVRLVGSSTRGRVEVFYQNVWGTVCDDSFDNLDALVVCRMLGFQRSTQVYTDGSGSGRIWLDELRCTGTESSIFNCPHAGMGINNCGHGEDVGVSCA
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0038024 (cargo receptor activity), GO:0033218 (amide binding), GO:0042277 (peptide binding), GO:0001540 (amyloid-beta binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0051234 (establishment of localization), GO:0009605 (response to external stimulus), GO:0006950 (response to stress), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006952 (defense response), GO:0043207 (response to external biotic stimulus), GO:0009617 (response to bacterium), GO:0006810 (transport), GO:0098542 (defense response to other organism), GO:0016192 (vesicle-mediated transport), GO:0042742 (defense response to bacterium), GO:0006909 (phagocytosis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: RNA helicase (A0A8M2BF62)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm
InterPro domains:
- IPR001650: Helicase, C-terminal domain-like (domain) [482-643]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [203-648]
- IPR011545: DEAD/DEAH-box helicase domain (domain) [267-458]
- IPR014014: RNA helicase, DEAD-box type, Q motif (domain) [243-271]
- IPR000629: ATP-dependent RNA helicase DEAD-box, conserved site (conserved_site) [413-421]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [262-486]
Sequence:
MSHVVVDGSHGLDQQLAVLDLNSADGQGVGTGRRYIPPHLRNKDASKNAGNAYSSGRQSGYSVAPVQSYSPGWDGSRTNGFVNGYHDSRMNGTANFARGPLRNDRGGRGGFRGNRNGASFNQPVHNAGYGTYENKDGGWNSVVNRDAYASFGGRSDRGKSAFFNDRGASSRGRYERGGFGGGTGGNSRWVEESRDEEDWSKPMPPNERLEHELFSASNTGINFEKYDDIPVEATGTNSPGHIESFHDVDMGEIIMGNITLSRYTRPTPVQKYAIPIIKTKRDLMACAQTGSGKTAAFLLPVLSQIYSEGPGEALQATKASTQQENGKYVRRKQYPISLVLAPTRELALQIYDEARKFAYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDYCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGSRQTMMFSATFPKEIQILARDFLEEYIFLAVGRVGSTSENITQKVVWVEENDKRSFLLDLLNATGKDSLTLVFVETKKGADALEDFLYREGYACTSIHGDRSQRDREEALHQFRSGRCPIMVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFYNDKNSNITKDLLDILVEAKQEVPSWLENLAYEHQHKSTNRGRPKRFSGGFGARDYRQMPGGGNTFGNRGARNTGGHGGNRGFGGNKGGFGSFGGDSYGGTYGNYGGNYTQVDWWGN
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0048870 (cell motility), GO:0042221 (response to chemical), GO:0050900 (leukocyte migration), GO:0042330 (taxis), GO:0097529 (myeloid leukocyte migration), GO:0006935 (chemotaxis), GO:0030595 (leukocyte chemotaxis), GO:0070887 (cellular response to chemical stimulus), GO:0016477 (cell migration), GO:0071621 (granulocyte chemotaxis), GO:0060326 (cell chemotaxis), GO:0097530 (granulocyte migration), GO:1990266 (neutrophil migration), GO:0030593 (neutrophil chemotaxis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0043229 (intracellular organelle), GO:0035770 (ribonucleoprotein granule), GO:0036464 (cytoplasmic ribonucleoprotein granule), GO:0045495 (pole plasm), GO:0043228 (non-membrane-bounded organelle), GO:0043186 (P granule), GO:0060293 (germ plasm), GO:0043232 (intracellular non-membrane-bounded organelle)
Protein: Receptor-type tyrosine-protein phosphatase epsilon isoform X2 (A0A8M9PXB4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR029021: Protein-tyrosine phosphatase-like (homologous_superfamily) [121-709]
- IPR000242: Tyrosine-specific protein phosphatase, PTPase domain (domain) [150-701]
- IPR000387: Tyrosine-specific protein phosphatases domain (domain) [329-690]
- IPR016130: Protein-tyrosine phosphatase, active site (active_site) [348-648]
- IPR003595: Protein-tyrosine phosphatase, catalytic (domain) [307-698]
- IPR050348: Protein-Tyrosine Phosphatase (family) [95-509]
Sequence:
MVLVLFLSVTTPQVTTNATENNHGDPGPFNTHILSILLGLSVLLLFLGLLTWYCLRLKNQRKAVITAVDKKVPNGILEEQEEYIDVDVDVDMDMDMDEDEDEDDLGWPSEEQQTVVLLPRSPSTSKTYLPIPVDNLEEEYRIRSADDGKLFREEYSSLPGGSIQGTCEEANKEENKEKNRYPNILPYDQSRVILTPMDGVTCSDYINASYIDGYKDKNKFIAAQGPKQDTTADFWRMIWEQKSSTIVMLTNLKERKEDKCYQYWPDQGCWTYGNVRVAVEDFTVLVDYTIRKFCVQYASDGSKSPRLVTQLHFTSWPDFGVPFSPIGMLKFLKKVKQVNPSYAGPIVVHCSAGVGRTGTFIVIDAMIDMMHTEQKVDVFGFVSRIREQRSQLIQTDLQYSFVYQALLEYFLYGDTELDVSSLEGHLQKLHNTNAPLDRVGLEEEFKKLTNMRIMKENMRTGNLPANMKKNRVLQIIPYDFNRVILSMKRGQEFTDYVNASFIDGYRQKDYYIATQGPLVHTVDDFWRMAWEWKCHSIVMLTELQERDQDKCFQYWPSEDSVTYGEFSVEIKGDTLCETFSLRDLVLTHTPEKQTRLVRHFHFHGWPEIGIPAEGKGMIDIIAAVQKQQQQSGNHPIIVHCSAGAGRTGTFIALSNILERVKAEGLLDVFQTVKSLRMQRPHMVQTVEQYDFCYRVVQDFVDIFSDYANFK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0004721 (phosphoprotein phosphatase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0004725 (protein tyrosine phosphatase activity), GO:0016791 (phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009888 (tissue development), GO:0009790 (embryo development), GO:0048598 (embryonic morphogenesis), GO:0048729 (tissue morphogenesis), GO:0060429 (epithelium development), GO:0007369 (gastrulation), GO:0060027 (convergent extension involved in gastrulation), GO:0002009 (morphogenesis of an epithelium), GO:0060026 (convergent extension)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Tropomyosin alpha-3 chain isoform X4 (A0A8M2B695)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytoskeleton
InterPro domains:
- IPR000533: Tropomyosin (family) [8-247]
Sequence:
MAGSNSIDAVKRKIKVLQQQADEAEERAEILQRQVEEEKRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELAESKCAELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0051015 (actin filament binding), GO:0008092 (cytoskeletal protein binding), GO:0003779 (actin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0009653 (anatomical structure morphogenesis), GO:0030029 (actin filament-based process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0032989 (cellular component morphogenesis), GO:0016043 (cellular component organization), GO:0061061 (muscle structure development), GO:0044085 (cellular component biogenesis), GO:0030036 (actin cytoskeleton organization), GO:0010927 (cellular component assembly involved in morphogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0022607 (cellular component assembly), GO:0042692 (muscle cell differentiation), GO:0006996 (organelle organization), GO:0030239 (myofibril assembly), GO:0031032 (actomyosin structure organization), GO:0055001 (muscle cell development), GO:0097435 (supramolecular fiber organization), GO:0070925 (organelle assembly), GO:0007010 (cytoskeleton organization), GO:0014866 (skeletal myofibril assembly), GO:0051146 (striated muscle cell differentiation), GO:0055002 (striated muscle cell development), GO:0140694 (non-membrane-bounded organelle assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0030017 (sarcomere), GO:0005737 (cytoplasm), GO:0036379 (myofilament), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043292 (contractile fiber), GO:0043229 (intracellular organelle), GO:0005865 (striated muscle thin filament), GO:0043228 (non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0030016 (myofibril), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015629 (actin cytoskeleton)
Protein: Voltage-gated potassium channel subunit beta-1 (A0A8M2B9B9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side
InterPro domains:
- IPR023210: NADP-dependent oxidoreductase domain (domain) [82-384]
- IPR005400: Potassium channel, voltage-dependent, beta subunit, KCNAB1 (family) [286-383]
- IPR005983: Potassium channel, voltage-dependent, beta subunit, KCNAB (family) [67-385]
- IPR036812: NAD(P)-dependent oxidoreductase domain superfamily (homologous_superfamily) [66-391]
- IPR005399: Potassium channel, voltage-dependent, beta subunit, KCNAB-related (family) [1-397]
Sequence:
MQVSFVCTDHRAVSRSTEDRLNRQNTNSPSLGTKSKFRAVAMVARSLGQLSVQNMPSAGDHCLKTGMKYRNLGKSGLRVSCLGLGTWVTFGGQITDEIAEQLMTLAYENGINLFDTAEVYAAGKAEMVLGSIIKKKGWRRSSLVITTKIYWGGKAETERGLSRKHIIEGLRASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLIPPVCEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIISGKYDSGVPPCSRASLKGYQWMKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSCVLLGASSTDQLMENIGAIQVLPKLSSSIIHEVDSILGNKPYSKKDYRS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0016247 (channel regulator activity), GO:0005515 (protein binding), GO:0099106 (ion channel regulator activity), GO:0015459 (potassium channel regulator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0065008 (regulation of biological quality), GO:0098900 (regulation of action potential), GO:0051239 (regulation of multicellular organismal process), GO:0050794 (regulation of cellular process), GO:0010646 (regulation of cell communication), GO:0042391 (regulation of membrane potential), GO:0044057 (regulation of system process), GO:0051969 (regulation of transmission of nerve impulse), GO:0031644 (regulation of nervous system process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:1990351 (transporter complex), GO:0098797 (plasma membrane protein complex), GO:1902495 (transmembrane transporter complex), GO:0005886 (plasma membrane), GO:0034702 (ion channel complex), GO:0008076 (voltage-gated potassium channel complex), GO:0034703 (cation channel complex), GO:0034705 (potassium channel complex)
Protein: Nucleolar and coiled-body phosphoprotein 1 isoform X1 (A0A8M3B7S8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus, nucleolus
InterPro domains:
- IPR007718: Srp40, C-terminal (domain) [925-997]
- IPR006594: LIS1 homology motif (conserved_site) [7-39]
- IPR039191: Nopp140-like (family) [3-755]
Sequence:
MAEDSTVPSDLYQHVYSFLVENKFAKAAKEFLRQAKVKPQDQNEDSLMDIFNFWVKSPETKKRKAVTSGPAAVNGPSAKKAKKDADSSSSEDSSSEEEQAAPAKKAVQVKAPPPKKPAAVATKESSSEDSSDSEDEAPAKTTAKKPAAVKAAVQPAAAARKKDTSSSSEESDSEEEPSKTPAKVVKPVTGTPKTVSTPVSAAQKKQDSSSEDSSSDSEDEPPAKSAVKAAVPVKTPPPAKPAAPAVSSSDDSSSDEEDAPPSKKPKTGQFSAVPPPGTLTAQAPVKTPASVKTVTPKAAAKNDSSSSDSSDSSSEDEAKKPAVKAAPAKAAPAKKAPTKVAPAQKKDSSSSDSSSSEDEATKPAIKVTPAKAASAKSTPAKAAQAKAAPAKVTPAAEESSSSSSEESEEESKKPAAKVAPGKAAAKRAPPKKTPAKVTPAAKESSPSSSDSEEDEPPTPAKATPAKAAPAKATPAKATPAKAAPAKKDDSSSSDSESSEDEAPAKPAATSKPVSTPKPGAKPAESSSASDSSSDEDEGPQKKPVTTPVSKPAPAKPPAAKTTNKPAESSSSSSDSSSDEEPKKKPATTPVSKPTPAKPTPTVKTTNKQAESSSDSSSDEEDKPQKKAATTPASKPVATSAKTTPAAKPAESSSDSDSSSDEEAQKKTTTPVPSKPATPAKPAAKAAESSSDSSDSEDETPAAKTAKPAAATATKSPAAASKPPVSASKPAAESSSSDSDSSSEDEKQAKTTVTPKAAPKPAVTPVNAKKAESSSSESSDSSDSETEAKKTPAKPVVANGKPVTKTPTSAAKTPAKKTAESSSSSDSSSDEEEPSKTPATKTPPATKTPPATKTPPATKTPPATKKQAAEAKAESSSSEESSEEEETPAATNGTQSAKKATPKNKKIATSTPQTFPRTKQKDSNAPFRRIREEDVEVDPRLKDNSFDAKMGANGDWGQKANNVLKFTKGKSFRHEKTKKKRGSYRGGAISTTVNSIKFDSD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009790 (embryo development), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:1904888 (cranial skeletal system development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048701 (embryonic cranial skeleton morphogenesis), GO:0048705 (skeletal system morphogenesis), GO:0048568 (embryonic organ development), GO:0001501 (skeletal system development), GO:0048562 (embryonic organ morphogenesis), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development), GO:0048704 (embryonic skeletal system morphogenesis), GO:0048706 (embryonic skeletal system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005634 (nucleus)
Protein: endothelin-converting enzyme 1 (A0A8M6Z1E9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasmic vesicle, secretory vesicle membrane. Membrane
InterPro domains:
- IPR024079: Metallopeptidase, catalytic domain superfamily (homologous_superfamily) [96-784]
- IPR000718: Peptidase M13 (family) [53-784]
- IPR008753: Peptidase M13, N-terminal domain (domain) [107-521]
- IPR042089: Peptidase M13, domain 2 (homologous_superfamily) [133-567]
- IPR018497: Peptidase M13, C-terminal domain (domain) [572-783]
Sequence:
MMSNYKRATFEEEDGTDVPVDGAISPDSVEVGFRKGGIQLFGPLGRRTQLEVVLAGLLLASLLALFGCAVTLGVRYNRDPARSICLTEACVTVASKIVEALDRSADPCQDFYQYACGGWVRKNPLPDGRSRWSTFNSIWDQNQAVLKHLLENGTFNSSSEAERKTQSYYLSCLNEQRIEELGAQPLMDLITKIGGWNITESWDKENFLDVLKIISGPYRAQPFFTVSVSVDPKNSNSNVIQVDQSGLFLPSRDYYLNKTNEKVLKAYLDYMVELGLLLGGDKNSTRGQMQQILDFETALANITVPQDERRDEEKIYHKITIADLQVLAPAIEWLDYLNSVLSPLELNDTEPVVVYAKEYMQQVSELINKTDHSLLNNYMIWNLVQKGASSLDQRFENAQDKLLESLYGTKKSCTPRWQTCIGNTDDTLGFALGALFVKATFDKQSKEIDLNGGAFLPSCGRNVNSTVHNLMFSVITQAEGMINEIRTAFKGALDDLKWMDEQTRQAAKDKADAIYDMIGFPDFILDSKELDDVYDGYEVTEDNFFQNMINFYNFSARVMADQLRKPPNRDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYAQDHPKALNFGGIGVVMGHELTHAFDDQGREYDKDGNLRSWWQNSSVEAFKNRTECMVDQYTQYTINGEHINGKQTLGENIADNGGLKAAYHAYRSWVQKNGEEKRLPAVNLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPHSPPKYRVIGTLSNSPEFAEHFQCPLGSSMNSGHRCEVW
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008237 (metallopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0043473 (pigmentation), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0048066 (developmental pigmentation), GO:0050931 (pigment cell differentiation), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0030318 (melanocyte differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0030141 (secretory granule), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle)