Protein: Basic helix-loop-helix ARNT-like protein 1 (A0A8M2BE61)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm. Nucleus, PML body
InterPro domains:
- IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [120-190]
- IPR001067: Nuclear translocator (family) [143-412]
- IPR001610: PAC motif (repeat) [457-500]
- IPR050933: Circadian Clock Transcription Factors (family) [42-673]
- IPR011598: Myc-type, basic helix-loop-helix (bHLH) domain (domain) [128-187]
- IPR000014: PAS domain (domain) [199-492]
- IPR013767: PAS fold (domain) [205-308]
- IPR035965: PAS domain superfamily (homologous_superfamily) [212-498]
Sequence:
MCFPAFFIGGSCQKASGNEERAALLYLCDDLMADQRMDISSTMNEFMSPSSTELISSSMGSTGMDFNRKRKGSITDYEIDGFSFESDSSWMRFLIPSSQLTQSPESDRDSMDTDKDKPLGRADQQMKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGAANPYTEANYKPAFLSDDELKHLILKAADGFLFVVGCDRGKILFVSESVYKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVRTDIAPSPSRLCSGARRSFFCRMKCNRSMVKMEDKDFPSTCSKKKADRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHPHIVPQPVNGDIRVKPTEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSFYEYFHQDDIGHLAECHRQVLQMREKINTHCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVVSGSSVDGAEPGFPQLSASPQSMDSVLTAADGSGKTVPGLPGGTRAGAGKIGRMIAEEVMEIHRIRGSSPSSCGSSPLNISNSTPPPDTSSPAARKMSNGGTPDIPSAGLGSGQDSIGYPYSNSSILSDNSHIGIGDIMDEPGSSSPSSDEAAMAIIMSLLEADAGLGGPVDFSDLPWPL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0048511 (rhythmic process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0009628 (response to abiotic stimulus), GO:0050793 (regulation of developmental process), GO:0048522 (positive regulation of cellular process), GO:0019222 (regulation of metabolic process), GO:0007623 (circadian rhythm), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0051239 (regulation of multicellular organismal process), GO:0048523 (negative regulation of cellular process), GO:0009892 (negative regulation of metabolic process), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:2000026 (regulation of multicellular organismal development), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0009314 (response to radiation), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0080090 (regulation of primary metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0009891 (positive regulation of biosynthetic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0009416 (response to light stimulus), GO:0051254 (positive regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:1901342 (regulation of vasculature development), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0051252 (regulation of RNA metabolic process), GO:0051253 (negative regulation of RNA metabolic process), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0010468 (regulation of gene expression), GO:0009648 (photoperiodism), GO:1902680 (positive regulation of RNA biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:1902679 (negative regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903507 (negative regulation of nucleic acid-templated transcription), GO:0045893 (positive regulation of DNA-templated transcription), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0045892 (negative regulation of DNA-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005667 (transcription regulator complex), GO:0000785 (chromatin), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome)