Protein: 60 kDa heat shock protein, mitochondrial (A0A7I2YQK6)
Organism: Homo sapiens (Human)
InterPro domains:
- IPR027409: GroEL-like apical domain superfamily (homologous_superfamily) [143-310]
- IPR001844: Chaperonin Cpn60/GroEL (family) [28-465]
- IPR002423: Chaperonin Cpn60/GroEL/TCP-1 family (family) [47-455]
- IPR027413: GroEL-like equatorial domain superfamily (homologous_superfamily) [25-465]
- IPR018370: Chaperonin Cpn60, conserved site (conserved_site) [339-350]
Sequence:
MLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGQKCEFQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGAMGGMGGGMGGGMF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:1901363 (heterocyclic compound binding), GO:0008289 (lipid binding), GO:0044877 (protein-containing complex binding), GO:0097159 (organic cyclic compound binding), GO:0097367 (carbohydrate derivative binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0034185 (apolipoprotein binding), GO:0051087 (chaperone binding), GO:0051082 (unfolded protein binding), GO:0071814 (protein-lipid complex binding), GO:0002039 (p53 binding), GO:0019899 (enzyme binding), GO:0001530 (lipopolysaccharide binding), GO:0071813 (lipoprotein particle binding), GO:0044389 (ubiquitin-like protein ligase binding), GO:0003723 (RNA binding), GO:0031625 (ubiquitin protein ligase binding), GO:0003725 (double-stranded RNA binding), GO:0008035 (high-density lipoprotein particle binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0009987 (cellular process), GO:0019222 (regulation of metabolic process), GO:0032879 (regulation of localization), GO:0065008 (regulation of biological quality), GO:0006457 (protein folding), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0048522 (positive regulation of cellular process), GO:1903829 (positive regulation of protein localization), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0060341 (regulation of cellular localization), GO:0060255 (regulation of macromolecule metabolic process), GO:0051130 (positive regulation of cellular component organization), GO:0061077 (chaperone-mediated protein folding), GO:0031647 (regulation of protein stability), GO:0009891 (positive regulation of biosynthetic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0051128 (regulation of cellular component organization), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0051052 (regulation of DNA metabolic process), GO:0051054 (positive regulation of DNA metabolic process), GO:1904951 (positive regulation of establishment of protein localization), GO:0070201 (regulation of establishment of protein localization), GO:0032880 (regulation of protein localization), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0033043 (regulation of organelle organization), GO:0050821 (protein stabilization), GO:1900182 (positive regulation of protein localization to nucleus), GO:0010638 (positive regulation of organelle organization), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0032204 (regulation of telomere maintenance), GO:2000573 (positive regulation of DNA biosynthetic process), GO:2001252 (positive regulation of chromosome organization), GO:0032206 (positive regulation of telomere maintenance), GO:2000278 (regulation of DNA biosynthetic process), GO:1900180 (regulation of protein localization to nucleus), GO:0033044 (regulation of chromosome organization), GO:0032210 (regulation of telomere maintenance via telomerase), GO:0032212 (positive regulation of telomere maintenance via telomerase), GO:1904358 (positive regulation of telomere maintenance via telomere lengthening), GO:1904356 (regulation of telomere maintenance via telomere lengthening)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)