Protein: Glycylpeptide N-tetradecanoyltransferase 1 (A0A7I2V3U5)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytosol. Membrane; Peripheral membrane protein
InterPro domains:
- IPR022676: Glycylpeptide N-tetradecanoyltransferase, N-terminal (domain) [141-294]
- IPR000903: Glycylpeptide N-tetradecanoyltransferase (family) [63-337]
- IPR022678: Glycylpeptide N-tetradecanoyltransferase, conserved site (conserved_site) [244-252]
- IPR016181: Acyl-CoA N-acyltransferase (homologous_superfamily) [115-337]
Sequence:
MADESETAVKPPAPPLPQMMEGNGNGHEHCSDCENEEDNSYNRGGLSPANDTGAKKKKKKQKKKKEKGSETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPEASAAPGGGQGAERGQGEPGCQQERRALGGEGAFSYWKSEPAHSLQISWTFYFCYLKQDFILV
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0005515 (protein binding), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0019107 (myristoyltransferase activity), GO:0016410 (N-acyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0009987 (cellular process), GO:0051641 (cellular localization), GO:0009058 (biosynthetic process), GO:0032879 (regulation of localization), GO:0006807 (nitrogen compound metabolic process), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0051050 (positive regulation of transport), GO:0065008 (regulation of biological quality), GO:0044237 (cellular metabolic process), GO:0048522 (positive regulation of cellular process), GO:0044281 (small molecule metabolic process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0044238 (primary metabolic process), GO:0090559 (regulation of membrane permeability), GO:0042180 (cellular ketone metabolic process), GO:1903829 (positive regulation of protein localization), GO:0051049 (regulation of transport), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0032388 (positive regulation of intracellular transport), GO:0060341 (regulation of cellular localization), GO:0019538 (protein metabolic process), GO:0009966 (regulation of signal transduction), GO:0051649 (establishment of localization in cell), GO:0032101 (regulation of response to external stimulus), GO:0044249 (cellular biosynthetic process), GO:0051130 (positive regulation of cellular component organization), GO:0043170 (macromolecule metabolic process), GO:0046907 (intracellular transport), GO:0010646 (regulation of cell communication), GO:0006810 (transport), GO:0016043 (cellular component organization), GO:0051222 (positive regulation of protein transport), GO:0051128 (regulation of cellular component organization), GO:0044260 (cellular macromolecule metabolic process), GO:0006839 (mitochondrial transport), GO:0009059 (macromolecule biosynthetic process), GO:0090316 (positive regulation of intracellular protein transport), GO:1904951 (positive regulation of establishment of protein localization), GO:0070201 (regulation of establishment of protein localization), GO:1905710 (positive regulation of membrane permeability), GO:0008277 (regulation of G protein-coupled receptor signaling pathway), GO:0022400 (regulation of rhodopsin mediated signaling pathway), GO:0032880 (regulation of protein localization), GO:1905477 (positive regulation of protein localization to membrane), GO:1901028 (regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway), GO:0036211 (protein modification process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0046902 (regulation of mitochondrial membrane permeability), GO:0051223 (regulation of protein transport), GO:0043412 (macromolecule modification), GO:0033043 (regulation of organelle organization), GO:0034645 (cellular macromolecule biosynthetic process), GO:0042157 (lipoprotein metabolic process), GO:0006996 (organelle organization), GO:0010638 (positive regulation of organelle organization), GO:0061024 (membrane organization), GO:0032386 (regulation of intracellular transport), GO:0007005 (mitochondrion organization), GO:1905475 (regulation of protein localization to membrane), GO:0010821 (regulation of mitochondrion organization), GO:0031365 (N-terminal protein amino acid modification), GO:0010822 (positive regulation of mitochondrion organization), GO:0033157 (regulation of intracellular protein transport), GO:0043543 (protein acylation), GO:0018193 (peptidyl-amino acid modification), GO:0042158 (lipoprotein biosynthetic process), GO:0006497 (protein lipidation), GO:0007006 (mitochondrial membrane organization), GO:0035794 (positive regulation of mitochondrial membrane permeability), GO:1903747 (regulation of establishment of protein localization to mitochondrion), GO:1903749 (positive regulation of establishment of protein localization to mitochondrion), GO:0006498 (N-terminal protein lipidation), GO:0018377 (protein myristoylation), GO:0006499 (N-terminal protein myristoylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0019898 (extrinsic component of membrane), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)