Protein: Progressive external ophthalmoplegia 1 homolog (Human) (Predicted) (A6JHH4)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR034154: Archaeal primase DnaG/twinkle-like, TOPRIM domain (domain) [260-336]
- IPR007694: DNA helicase, DnaB-like, C-terminal (domain) [385-636]
- IPR027032: Twinkle-like protein (family) [52-641]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [383-637]
Sequence:
MWLLLRRAYPLRILLPLRGEWMGRRGLPRSLAPGPPRRRYRKEALPALEVPVSPVTTTEIRQYLRAHGIPFQDGHSCLRAPSPFVAPSDIKNQKKDATTSFCLFIDKTTGHFLCMTSLAEGSWEDLQASVEGRGDGAKEGILLGEGPEAEDREEVLRIWNRAIPLWELPDPQETQLARVMFGLTKVTDDTLRRFNVRYLRSTRSLVFPWFTPGSSGLRGLKLLGVEGQENGVQYVETTIPRPGVYHNLFGLPLIGRRDTEVVLTSRELDSLALSQSTGLPTLSLPRGTVCLPPALLPYLEQFRRIVFWLGDDLRSWEAAKLFARKLNPKRCSLVRPGNQQPRPLEALNQGLSLPRILRTALPAWHKSIVSFRQLREEVLGELSNVDQAAGVRWSRFPDLNRLLKGHRKGELTVFTGPTGSGKTTFISEYALDLCTQGVNTLWGSFEISNVRLARVMLTQFAVTRLEEQLDKYEEWADRFEDLPLYFMTFHGQQSIRSVIDTMQHAVYVYDVCHVVIDNLQFMMGHEQLSTDRIAAQDYIVGAFRKFATDNSCHVTLVIHPRKEDDDKELQTASIFGSAKASQEADNVLILQDRKLVTGPGKRYLQVSKNRFDGDVGVFPLEFNKSSLTFSIPPKSKARLKKIKDDNGLVAKKSSSGKKGSAHQNSETCIGQDPCQPDTSPSSR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0004386 (helicase activity), GO:1901363 (heterocyclic compound binding), GO:0008094 (ATP-dependent activity, acting on DNA), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0097159 (organic cyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003678 (DNA helicase activity), GO:0042802 (identical protein binding), GO:0019899 (enzyme binding), GO:0140097 (catalytic activity, acting on DNA), GO:0043139 (5'-3' DNA helicase activity), GO:0003677 (DNA binding), GO:0002020 (protease binding), GO:0003697 (single-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0042592 (homeostatic process), GO:0051716 (cellular response to stimulus), GO:0048878 (chemical homeostasis), GO:0019725 (cellular homeostasis), GO:0042221 (response to chemical), GO:0033500 (carbohydrate homeostasis), GO:0055082 (intracellular chemical homeostasis), GO:1901700 (response to oxygen-containing compound), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0009743 (response to carbohydrate), GO:0071310 (cellular response to organic substance), GO:0001678 (intracellular glucose homeostasis), GO:1901701 (cellular response to oxygen-containing compound), GO:0042593 (glucose homeostasis), GO:0071322 (cellular response to carbohydrate stimulus), GO:0071333 (cellular response to glucose stimulus), GO:0034284 (response to monosaccharide), GO:0071326 (cellular response to monosaccharide stimulus), GO:0009746 (response to hexose), GO:0009749 (response to glucose), GO:0071331 (cellular response to hexose stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)