Protein: Ras/Rap GTPase-activating protein SynGAP1b isoform X1 (A0A8M9NYZ5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR001849: Pleckstrin homology domain (domain) [211-338]
- IPR021887: Disabled homolog 2-interacting protein, C-terminal domain (domain) [1200-1419]
- IPR000008: C2 domain (domain) [327-447]
- IPR057606: Ras/Rap GTPase-activating protein SynGAP-like, PH domain (domain) [214-335]
- IPR001936: Ras GTPase-activating domain (domain) [461-798]
- IPR023152: Ras GTPase-activating protein, conserved site (conserved_site) [660-674]
- IPR008936: Rho GTPase activation protein (homologous_superfamily) [484-788]
- IPR039360: Ras GTPase-activating protein (family) [43-1392]
- IPR035892: C2 domain superfamily (homologous_superfamily) [347-486]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [258-346]
Sequence:
MLDQEEVHPLLMRERRSESHRNKLLRRTVSVPVEARHHPEMDAARLRRKSIATGKQPSMEIPPTAPPQPFRQSVSNPPFRPRSLSPSLSLSLPFAPSPLSPSLSPSHLQSQKRISTPPLPRSLPLSPSVSLTLPPSVPLSHWAAGEWKVVGSNPGTGSSVAALPSLESFLSRRLKGSIKRAKSQPKLDRTSSFRHMILPRFRSADQERTRLMQSFKESHSHESLLSPSSAAEALDLTLDEDAIIKPVHSSILGQEYCFEVITASGTKCFACRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPPKKRYYCELCLDDMLYARTTSKPRTDTVFWGEHFEFNNLPAVRNLRLHLYKETDKKRRKEKSTYLGLVSIPISSITGRQFVEQWYPVIQPSVLAKGGGVGGGKIINASLRLKSRFQTMSILPMELYKEFAEYVTNNYRTLCAVLEPLLSVKSKEEVACALVHILQSTGKAKDFLSDMAMCEVDRFIDREHLIFRENTLATKAIEEYLKLIGHKYLKDVLGDFIRALYESEENCEVDPMRTPPSILPEHQANLRMCCELALCKIINSYCAFPRELKEVFASWRVRCAERGREDIADRLISGSLFLRFLCPAIMSPSLFNLTQEYPDEQTSRTLTLIAKVVQNLANFSKFGSKEEYMCFMNEFLEMEWGSMQQFLYEISNLDSVSNAGAFEGYIDLGRELSILHSLLWEVMAQLSKDAIIKLGPLPRLLNDISMALRNPHLQRQPSHQTDRQPAERQTDRLLSRPSFNRGVSSEFQNLMMRDLNSSVEITRLPSPTSAMSSGGAPPSRAGMAGFADRDHPHRASSKDVFYGARPPLARSSPAYCTSSSDITDPDPKDSRMNSVSNLQSMGDMLNSSQASIAGLGSYGGLAGLGGGLGGQLRAGGRMSAGSGGSSMSGGLRLSQLSQMGTTTDSLSQQQQQQAAALRFPLSFQNPLFHLAADGPQLHHQHSRAQPPPPLLLAPEPDGSHPTYIPQFAHGGFSRSEDLSTLRPGPHLGQPSIIHSHSYSDDYSRHNQSDYGRRQISMHMQEQQQMAGMASQTGTSHSSLATPPSTVQPVRQSSMAPPTQRMKSQPSHQLSVSSAAGAPASKTRPQSGNLLQSPESGFGGRQQGPRQQLSVKDSTPPGLPHQQSSTRESQGSQGSQGGTPQSTQQSKSHQERQQVQQQHLLKPTMSKQGSSQSPSTLNPQTPASERTVAWVSNMPHLSADIESSRIDREEFKLKEYSKSMDESRLDRVREYEEEIHSLKERLMMSHRKLEEYERRLLTQEQQTNKILLQYQSRLDDSERRLRQQQMEKDNQIKGIIDRLMAVEDELRVGVVPEHKPRVFADQEKQLSALGSADPGVSFGGEMTSASGFVGVSPSDKSSTRSPQNGIASFPLVPPPRSIPHAQLWPNGNQKSAMDWRASLEGEQVNNNANQI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0008047 (enzyme activator activity), GO:0060589 (nucleoside-triphosphatase regulator activity), GO:0030695 (GTPase regulator activity), GO:0005096 (GTPase activator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0007610 (behavior), GO:0009887 (animal organ morphogenesis), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007626 (locomotory behavior), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0048854 (brain morphogenesis), GO:0007399 (nervous system development), GO:0036269 (swimming behavior)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)