Protein: G protein-coupled receptor kinase (A0A8M9QKR0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [301-313]
- IPR000719: Protein kinase domain (domain) [180-443]
- IPR000961: AGC-kinase, C-terminal (domain) [444-509]
- IPR036305: RGS domain superfamily (homologous_superfamily) [32-175]
- IPR000239: GPCR kinase (family) [161-513]
- IPR017441: Protein kinase, ATP binding site (binding_site) [186-214]
- IPR044926: RGS, subdomain 2 (homologous_superfamily) [74-147]
- IPR016137: RGS domain (domain) [52-165]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [177-507]
Sequence:
MEIETMAANCALLKARDAGNAYRKGRSRKWKEILHFPHINQCKELENSIERDYYSLCVNQPIGKQLFKLFCATEPKLQHLIDLLEEMAKYEVTTDDLKKTSRDKLINKFKTSQSSMVREMVHKEMQNGNLNMENFISSCHSALHEYLSGAPFSEYQNSMYFDRFLQWKMVERRPVTQDNFREYRILGKGGFGEVCACQSRASGKMYACKKLVKKRVKRQGGEKMVLKEKQILERVNSRFVVSLAYTYETKDSLCLVLTVMDGGDLGFHIYKMGNQKLDKNRVQFYAAEVLCGLDHLHKHNVVYRDLKPENILLDYEGHIRISDLGLAEILPENKLVKGRVGTAGYMAPEVVAGTSYGVSVDWWGLGCLIYEMTAKKPPFRNHKEQISKKDLEQRILEKVELYDKMFDEETQNICQKLLAKNPKERLGCRSGQGAEVIKSHQFFKNINFTLLEAGMMQPPFIPDPRAIYCDDVSDIDQFAAVKGVTLDEADEAFYAEFNTGSVTVPWQTEAKDEPAEPILSKSSAGYEKL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0048856 (anatomical structure development), GO:0023056 (positive regulation of signaling), GO:0007275 (multicellular organism development), GO:0051239 (regulation of multicellular organismal process), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0010647 (positive regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0048513 (animal organ development), GO:0010646 (regulation of cell communication), GO:0048731 (system development), GO:0044057 (regulation of system process), GO:0030111 (regulation of Wnt signaling pathway), GO:0030177 (positive regulation of Wnt signaling pathway), GO:1903522 (regulation of blood circulation), GO:0072359 (circulatory system development), GO:0007507 (heart development), GO:0008016 (regulation of heart contraction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:0042995 (cell projection), GO:0120025 (plasma membrane bounded cell projection)