Protein: Mitochondrial Rho GTPase (A6HHA9)
Organism: Rattus norvegicus (Rat)
Function: Mitochondrial GTPase involved in mitochondrial trafficking
Subcellular location: Membrane; Single- pass type IV membrane protein. Mitochondrion outer membrane; Single-pass type IV membrane protein
InterPro domains:
- IPR001806: Small GTPase (family) [19-559]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [210-222]
- IPR011992: EF-hand domain pair (homologous_superfamily) [181-381]
- IPR020860: MIRO domain (domain) [15-592]
- IPR013567: EF hand associated, type-2 (domain) [232-317]
- IPR021181: Mitochondrial Rho GTPase (family) [14-670]
- IPR005225: Small GTP-binding domain (domain) [16-175]
- IPR002048: EF-hand domain (domain) [317-352]
- IPR052266: Mitochondrial Rho GTPase/EF-hand domain-containing protein (family) [149-455]
- IPR013566: Mitochondrial Rho GTPase 1/3, EF hand associated, type-1 (domain) [354-426]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [9-598]
Sequence:
MRAGRVRPLRASDMKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHLSDGVADSGLTLRGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFQVFPYIPWGPDVNNTVCTNESGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAITVTRDKKIDLQKKQTQRNVFRCNVIGVKGCGKTGVLQSLLGRNLMRQKKIRDDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAEIVCDVVCLVYDVTNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEHSVSPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPHARLRCMCTCNRCTFCICQNLLNSDLLQSVKNKVFTAVLNRHVTQADLKSSTFWLRASFGATVFAVVGFAMYRALLKQR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0065008 (regulation of biological quality), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0051234 (establishment of localization), GO:0023051 (regulation of signaling), GO:0007017 (microtubule-based process), GO:0051640 (organelle localization), GO:0007018 (microtubule-based movement), GO:1903530 (regulation of secretion by cell), GO:0051049 (regulation of transport), GO:0051646 (mitochondrion localization), GO:0010646 (regulation of cell communication), GO:0051656 (establishment of organelle localization), GO:0060341 (regulation of cellular localization), GO:0001505 (regulation of neurotransmitter levels), GO:0099177 (regulation of trans-synaptic signaling), GO:0032886 (regulation of microtubule-based process), GO:0051588 (regulation of neurotransmitter transport), GO:0051654 (establishment of mitochondrion localization), GO:0046928 (regulation of neurotransmitter secretion), GO:0050804 (modulation of chemical synaptic transmission), GO:0051046 (regulation of secretion), GO:0060632 (regulation of microtubule-based movement), GO:0034643 (establishment of mitochondrion localization, microtubule-mediated), GO:0032386 (regulation of intracellular transport), GO:1902513 (regulation of organelle transport along microtubule)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)