Protein: Beta-galactosidase (A0A8M2B6W2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans
InterPro domains:
- IPR031330: Glycoside hydrolase 35, catalytic domain (domain) [35-350]
- IPR017853: Glycoside hydrolase superfamily (homologous_superfamily) [25-349]
- IPR001944: Glycoside hydrolase, family 35 (family) [21-636]
- IPR008979: Galactose-binding-like domain superfamily (homologous_superfamily) [470-637]
- IPR048912: Beta-galactosidase 1-like , first all-beta domain (domain) [397-508]
- IPR048913: Beta-galactosidase, galactose-binding domain (domain) [540-601]
- IPR026283: Beta-galactosidase 1-like (family) [19-633]
- IPR019801: Glycoside hydrolase, family 35, conserved site (conserved_site) [171-183]
Sequence:
MILSFSSNQNKWHLTSAPLFTVSNTMTPGVGLVSVLLLIIPATTYATTPTFSVDYHRNCFLKDGEPFRYISGSIHYSRIPRVYWKDRLLKMYMAGLNAIQTYVPWNFHEAVPGQYDFSGDRDLEQFLQLCQDIGLLVIMRPGPYICAEWDMGGLPAWLLKKKDIVLRSSDPDYLAAVDKWMGKLLPIIKRYLYQNGGPIITVQVENEYGSYFACDFNYMRHLSQLFRFYLGEEAVLFTTDGAGLGYLKCGSLQGLYATVDFGPGANVTAAFEAQRHVEPRGPLVNSEFYPGWLDHWGEKHSVVPTSAVVKTLNEILEIGANVNLYMFIGGTNFGYWNGANTPYGPQPTSYDYDSPLTEAGDLTEKYFAIREVIKMYKDVPEGILPPSTPKFAYGKVQMKKLKTVSETLDVLSFSGPVKTLYPPTFIEMNQAFGFVLYQTVLPVNCVKPTPLSSPLNGVHDRAYISIDGTAAGILERNKALSINITGKAGSRVDVLVENMGRINYGKGINDFKGLVFNLTLGADVLVNWTVYSLSVDEAVSKGLLLASGSSSTSSTSTPPPALSPPTFYTGSFIIPDGIPDLPQDTYIQFPDWRKGQVWINGFNVGRYWPSRGPQITLFVPAHLLSTSVQNNITVLELEASPCSSGSCMVEFTDTPILNGTVNGQYKRQLFNKQDLF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds), GO:0015925 (galactosidase activity), GO:0004565 (beta-galactosidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901575 (organic substance catabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0044248 (cellular catabolic process), GO:0046700 (heterocycle catabolic process), GO:0044270 (cellular nitrogen compound catabolic process), GO:1901657 (glycosyl compound metabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:1901136 (carbohydrate derivative catabolic process), GO:0019439 (aromatic compound catabolic process), GO:1901361 (organic cyclic compound catabolic process), GO:1901658 (glycosyl compound catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0097546 (ciliary base), GO:0043227 (membrane-bounded organelle), GO:0120025 (plasma membrane bounded cell projection), GO:0005929 (cilium)