Protein: Jarid1a protein (B5DFF8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus
InterPro domains:
- IPR047973: Lysine-specific demethylase 5A, first PHD-finger (domain) [295-343]
- IPR019786: Zinc finger, PHD-type, conserved site (conserved_site) [296-340]
- IPR036431: ARID DNA-binding domain superfamily (homologous_superfamily) [61-184]
- IPR001606: ARID DNA-binding domain (domain) [84-175]
- IPR019787: Zinc finger, PHD-finger (domain) [293-343]
- IPR001965: Zinc finger, PHD-type (domain) [295-341]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [275-336]
- IPR003347: JmjC domain (domain) [437-579]
- IPR003349: JmjN domain (domain) [18-60]
- IPR047974: Lysine-specific demethylase 5A, ARID domain (domain) [84-175]
- IPR011011: Zinc finger, FYVE/PHD-type (homologous_superfamily) [288-350]
Sequence:
MAGVGPGGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPPFACEVNTFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYALSKIVASKGGFEIVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMGVQMPDLDLKEKVEAEVLSTDIQPSPERGTRMNIPPKRTRRVKSQSDSGEVNRNTELKKLQIFGAGPKVVGLAVGAKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLLPPLPDVPKGDWRCPKCVAEECNKPREAFGFEQAIREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGSGFPIKDGQRKMLPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMNPNVLMEHGVPVSLLCLPSTFLKIFYLLIRVLFMFWGEL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0032451 (demethylase activity), GO:0140457 (protein demethylase activity), GO:0032452 (histone demethylase activity), GO:0032453 (histone H3K4 demethylase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0019953 (sexual reproduction), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0044238 (primary metabolic process), GO:0007276 (gamete generation), GO:1901564 (organonitrogen compound metabolic process), GO:0048731 (system development), GO:0019538 (protein metabolic process), GO:0048513 (animal organ development), GO:0048608 (reproductive structure development), GO:0045137 (development of primary sexual characteristics), GO:0007548 (sex differentiation), GO:0046661 (male sex differentiation), GO:0043170 (macromolecule metabolic process), GO:0007283 (spermatogenesis), GO:0036211 (protein modification process), GO:0061458 (reproductive system development), GO:0043412 (macromolecule modification), GO:0008406 (gonad development), GO:0046546 (development of primary male sexual characteristics), GO:0048232 (male gamete generation), GO:0008584 (male gonad development), GO:0016570 (histone modification)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)