lokahq/bioreason-rl huggingface dataset:
Protein: RAS guanyl-releasing protein 1 isoform X5 (A0A8M2BKX7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR036964: Ras guanine-nucleotide exchange factor, catalytic domain superfamily (homologous_superfamily) [154-423]
- IPR002219: Protein kinase C-like, phorbol ester/diacylglycerol-binding domain (domain) [504-554]
- IPR008937: Ras-like guanine nucleotide exchange factor (family) [23-402]
- IPR001895: Ras guanine-nucleotide exchange factors catalytic domain (domain) [162-398]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [444-456]
- IPR011992: EF-hand domain pair (homologous_superfamily) [421-492]
- IPR000651: Ras-like guanine nucleotide exchange factor, N-terminal (domain) [17-142]
- IPR002048: EF-hand domain (domain) [431-466]
- IPR023578: Ras guanine nucleotide exchange factor domain superfamily (homologous_superfamily) [21-423]
- IPR020454: Diacylglycerol/phorbol-ester binding (domain) [502-555]
- IPR046349: C1-like domain superfamily (homologous_superfamily) [492-554]
Sequence:
MTCPSAQEISRALQSPPAHASFRSASLDELILRCLHCFDSDGKLNRGTQLVSMTLMMHNWVVPSHIFAHKLLSLYKDCPAEKRGQRRPQICHFIRQWISQFRLMFEMDPLLEKAMGDLWALVSAEGTNSHHQLINTPYINPPVNISQTPSPLVKKRKVSLLFDHMEPDEMAEHLSYLEFKNFCNVSFLDYRSYVVHGSVRDNPALERSVMLCNGVSQWVQLMILNRHTSQQRAEVFTKFIHVAQKLRSLQNFNTLMAVIGGLCHSSISRLKDTASLLSSDVTKTLSELTELLSSYSNYSNYRRVYSECTGFKVPILGVHLKDLISLNEALPDYLEDDKINLGKLQHLYSNISDLLAIHDCTPPFEANKDLLHLLTLSLDLYYTEDEIYELSYAKEPKNPKIQPVAPVKPPVVAEWGSGVTPRLDPATISKHVKQMVDSIMKNYDLNMDGYISLEEFEKIAANFPFSFCTHESDREGEISREEITSYFMRGMSVCAKLGFNLHNLHNFHETTYKRPTFCDTCGGFLWGVIKQGYHCKDCGVNCHKHCKDVVGMECLKRLQVNSSSCPCTPGPVSGLHTKGNSWSEFSQSFQSGSEEEAFVFPNGNESEHSKGQTSSDSDAEAATLSDRSTQTEPGVWTPVAKRKDRLHSQKQHPPLEKSATLPARVRGSSAPSSLLQEKMDELKLNKDKRKEPD
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0140678 (molecular function inhibitor activity), GO:0019899 (enzyme binding), GO:0060589 (nucleoside-triphosphatase regulator activity), GO:0005085 (guanyl-nucleotide exchange factor activity), GO:0019900 (kinase binding), GO:0051020 (GTPase binding), GO:0030695 (GTPase regulator activity), GO:0031267 (small GTPase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0001945 (lymph vessel development), GO:0048731 (system development), GO:0001944 (vasculature development), GO:0072359 (circulatory system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: GRB2-associated-binding protein 1 isoform X4 (A0A8M9PTD5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR046355: GRB2-associated-binding protein 1-4-like (family) [1-723]
- IPR001849: Pleckstrin homology domain (domain) [5-118]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [2-130]
Sequence:
MSGGDVVYSGWLRKSPPEKKLRRYAWKKRWFVLRSGRLSGDPDVLEYYKNDHAKKPIRVIDLNLCEQVDAGLSFNKKDLEHSFIFDIKTIDRIFYLVAETEEDMNKWVRNICEICGFNPTDTEDSAKVSHHVNVPGGLVVDMAPSGGLGGALGASALANLPPPYQPVSIRQLGSSSSLDEPQDYLWLLNCESKKPEPNSLVAPLCLGEEEQEYLLLEECESRSAAHDSQAHGDCSKSTSSEPDCNDNLPSHYTPTSSTSKNAPVNGFFSTQHPTGLYDSPPLRGQSLSADSQGLYHLPRSYSQDTVLLPKSATSPPIPDGEPGELYVFNTPGRKPSLEAHLRNLSVSYDIPPTPGSNSTYQVPRTAGVEAVSGSTEVIPPPRPPKPSVSGGSVPPERSPTDTYVVPRSVSETDTNYCVPTSAGGNKALRSNTIGTVDSSRLRKDYGSQDCYDIPRPFPSEKSCSFDFNESFNNYFKNKGMVPVGGVSTEEMDENYVPMSVHSLSHQRSGSLSEPIQEPNYVPMTPGTVEFSSLGKQVPPPAHMGFRSSPKTPPRRPIPISECQPPPIDRNLKPDRKVKPAPLEIKPVSEWEEYTAPVRSPVTRSFTREEESFYCTVPITPIKREVSGLDHLDENKLGAPMNADGGGSPMVKPKGDKQVEYLDLDLDPGKSTPPRKKKNNGTGISASDERVDYVLVDQQRTQALKSTREAWSDGRQSTEDTPTKGAK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0048856 (anatomical structure development), GO:0009653 (anatomical structure morphogenesis), GO:0009888 (tissue development), GO:0048729 (tissue morphogenesis), GO:0060429 (epithelium development), GO:0002009 (morphogenesis of an epithelium), GO:0002011 (morphogenesis of an epithelial sheet), GO:0090504 (epiboly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm)
Protein: P2X purinoceptor (A0A8M9QDM4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Receptor for ATP that acts as a ligand-gated ion channel
Subcellular location: Membrane; Multi-pass membrane protein
InterPro domains:
- IPR053792: ATP P2X receptor, conserved site (conserved_site) [253-279]
- IPR003045: P2X2 purinoceptor (family) [75-377]
- IPR001429: P2X purinoreceptor (family) [5-385]
- IPR027309: P2X purinoreceptor extracellular domain superfamily (homologous_superfamily) [57-345]
- IPR059116: ATP P2X receptor-like (family) [3-390]
Sequence:
MGCSAYCFHCLFDHGTPVILVVSSKKVGFIFRLLQLCIIVYVAVYVCWYKRAYQERDSVISSVSTKVKGNILTNSSALGTHVWDTSEYVIPPQGENSFFVLTNAIVTQGQTQGSCPEIPSEFTNCQSDSDCKEGLKEIRGNGMYSCVQTGKCVQYSETIKTCEVLSWCPLENDTVIPKPALLSAAEDFTVLIKNNIQYPKFKFRKRNILRHINSTYLKNCTFNHKTDPHCPVFRLGDIVTESGEDFSIMALKGGIIGIFIDWSCDLDFNERFCVPKYSFRRLDNKNPENNVAPGYNFRYAKYYMNNENTETRTLIKAFGIRFDVIVFGMAGKFNIVPTIVNVGAALALLNLMKVICDWFMLNCLSDSEYYSKHKFKHLKPKDESETFSFTDQSSYGTP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0015267 (channel activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0005261 (monoatomic cation channel activity), GO:0022839 (monoatomic ion gated channel activity), GO:0022836 (gated channel activity), GO:0099094 (ligand-gated monoatomic cation channel activity), GO:0022834 (ligand-gated channel activity), GO:0015276 (ligand-gated monoatomic ion channel activity), GO:0035381 (ATP-gated ion channel activity), GO:0004931 (extracellularly ATP-gated monoatomic cation channel activity), GO:0005230 (extracellular ligand-gated monoatomic ion channel activity), GO:0005231 (excitatory extracellular ligand-gated monoatomic ion channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0006811 (monoatomic ion transport), GO:0006812 (monoatomic cation transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Bromodomain-containing protein 8 isoform X3 (A0A8M2B3X0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR037966: Brd8, Bromo domain (domain) [664-767]
- IPR036427: Bromodomain-like superfamily (homologous_superfamily) [630-779]
- IPR001487: Bromodomain (domain) [660-768]
Sequence:
MSTGMGKHKMLSLGPTEPWSIREKLCLASSVMRSGDQNWVSVSRAIKPFSESGRPPDWFSQKHCASQYSQLLETTEAPKRKRGEKGEVVETIEDVIVRRLTAERIEELKRLIKDTQEKYRKLKKEVDLIQAGHVDPKLEELWAEIELKKKQEEEEAEQKKRATEAAYQIRQAAKNTPKRVPSVTVRSPPGASSPSMDILQPDASQPMTDESCASPMAQGVTVFMPVSDVMGPGPKESGLSSLVDDSPQKKHLAPKATPPPSPLLSELLKKGSLIAASSRLVVEGEVATGLSNGSHAVELHTSATVLPATQDITADAPTLSRLLESVTPAQQPVSADPPKPPTVVPPAPDHLSVPKSGDAAIAEGSGAEAVMAGSSTPAEVEGKETELVEEDTVVSVSYMGHELDLETVGDIIAIIEEKVDDPVEALDAAAVEAALSLCEDPAVGGHPLTSPWESQTFKAAEPEPMIQQSAIPAGAESAPNSAIVQGEMEVLVEEATETEAVEGVTEEPEVPSAPETEQSQDSEVKTEVERGGEGEGGVEETAQPENRTPSPAVKCEGEDWVQPETVTPCLDSEDSSASAKDAKEVKEEDGGSEVDVDEGMEMKECGDGDGEGPYLSEVDPPASESEDGYGSHSQRYTTADSTASSPASSQFSMCSEDQEALQAQKIWKKAIMLVWRAAANHRYASVFLQPVSDDIAPGYHSIVHRPMDLSAIKKNIESGQIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMALEMQRDVLEQIQQFLATQLIMQTSESGISTKSLRGREANRKQDPNEKTLSPAHKEPHLEPEPPARRKRNNSKQDTVEKDGGTRGRRSAIEADMKMKK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0030154 (cell differentiation), GO:0048468 (cell development), GO:0002244 (hematopoietic progenitor cell differentiation), GO:0030097 (hemopoiesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Metastasis-associated protein MTA2 isoform X2 (A0A8M2BJH3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR043151: Bromo adjacent homology (BAH) domain superfamily (homologous_superfamily) [2-142]
- IPR040138: Mesoderm induction early response protein/metastasis-associated protein (family) [1-506]
- IPR001005: SANT/Myb domain (domain) [264-313]
- IPR000949: ELM2 domain (domain) [145-256]
- IPR017884: SANT domain (domain) [263-315]
- IPR000679: Zinc finger, GATA-type (domain) [362-416]
- IPR001025: Bromo adjacent homology (BAH) domain (domain) [4-144]
- IPR035170: Metastasis-associated protein MTA1, R1 domain (domain) [449-525]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [266-318]
Sequence:
MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCLFRRRDISASLNTLADSNARDFEEESKQPSTSEQQKHQLKHRELFLSRQFESLPATHIRGKCNVTLLNETDVLTGYLEREDCFFYSLVFDPVQKTLLADQGEIRVGSKYQAEIPDKLAEVEADSRVQEKLETKVWDPNNQLKDPQIDQFLVVARAVGTFARALDCSSSIRQPSLHMSAAAASRDITLFHAMDTLQKNGYDLAKAMSTLVPQGGPVLCRDEMEEWSASEAMLFEEALEKYGKDFNDIRQDFLPWKSLASVVQFYYMWKTTDRYIQQKRLKAAEADSKLKQVYIPTYTKPNPNQITAPGNKPGMNGATGYQKGLSCESCHTAQSQQWYAWGPPNMQCRLCSSCWIYWKKYGGLKTPTQLEGATRASSEAAPRGHMTRQEVQGMSPFTSSAGRAKLLAKNRQTFILQTTKLTRIARRVCQDILQSRRAARRPYASINANAVKAECMIRLPKAAKSGVKNRPIPRPSLINIVKDLAIQAPLKLKAPRGAPTPINRNQVNQPRSASALLGKRPFDNAGGHLLSTNGRPFAMGMRAANQSVIKRQKVSQGDAPNPVVFVATKDTRYAFQEP
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0003712 (transcription coregulator activity), GO:0005515 (protein binding), GO:0003714 (transcription corepressor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0040007 (growth), GO:0048589 (developmental growth), GO:0048856 (anatomical structure development), GO:0031099 (regeneration), GO:0042246 (tissue regeneration), GO:0031101 (fin regeneration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Pituitary tumor-transforming gene 1 protein-interacting protein isoform X1 (A0A8M2BFI4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR052304: Pituitary tumor-transforming gene 1 protein-interacting (family) [19-170]
Sequence:
MIQTRTFLLSFVFFVFTFSVVVAQTAKSPVTNCTIKSNTTCEDCLKIVSCLWCISSQKCIDYPVNSVLPSHSVCPLSDARWGLCWMNFQILIITISVIAGVIVIAIFVCCFCCCKCENIGSKRSEERMENQASLRKFRHEERKAEMKQRHDEMRLKYGLKKDNQYSRFENS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0030097 (hemopoiesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0043227 (membrane-bounded organelle), GO:0120025 (plasma membrane bounded cell projection), GO:0005929 (cilium), GO:0097730 (non-motile cilium)
Protein: Protrudin (A0A8M3AL11)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell projection, growth cone membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein
InterPro domains:
- IPR017455: Zinc finger, FYVE-related (domain) [355-421]
- IPR000306: FYVE zinc finger (domain) [347-422]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [360-423]
- IPR042405: Protrudin (family) [12-421]
- IPR011011: Zinc finger, FYVE/PHD-type (homologous_superfamily) [335-420]
Sequence:
MQCSASSPQEPPQASAERPELTQLPTKDPSCADSASDPGSPKALTFDLLNMVICFKRMLIFLEPITDTLEVLRYLLGWKMPLFSLLSCVLLNILFLTLTEGSWFSLLLLAISAPAVLGFLGDRCQGASSEMALQKKKHYAVQRRDLQTVHMSKQEAMLEVKGMLKQIDDLLTQACVYAESVYKVLYWESHAVSSMFYGFLLTAVCLLYTAPVGVSLSVINSALFLWNRDFCRVLLKLKEFVHPTYVEPVEETELCDSDQANLLERTPTPTSVEDLSPGNIEEAEEAEPDDEFKDAIEESQLVLPETPLSLVDDEDVSSGVPEFDTVSDNGLLSRNEPIRSKVSKLTEKLRKRVPTNATGNCVQCNSAFSVLKKRRNCSNCGISFCSRCCSYKVFRSTMGATAPEAQRETVFVCSTCNTFLSTK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0032989 (cellular component morphogenesis), GO:0000902 (cell morphogenesis), GO:0016043 (cellular component organization), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0022008 (neurogenesis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0048858 (cell projection morphogenesis), GO:0030182 (neuron differentiation), GO:0032990 (cell part morphogenesis), GO:0048666 (neuron development), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0048812 (neuron projection morphogenesis), GO:0061564 (axon development), GO:0007409 (axonogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Cyclin-Y isoform X1 (A0A8M3ANE7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR013763: Cyclin-like domain (domain) [189-274]
- IPR006671: Cyclin, N-terminal (domain) [181-281]
- IPR036915: Cyclin-like superfamily (homologous_superfamily) [189-281]
- IPR012399: Cyclin Y (family) [1-357]
Sequence:
MGNSTSCCVSSSPKLRRNAHSRLEPYRPEPELSREDTGCNLQHISDRENIDELNMEYNPSDHPRASTIFLSKSQTDVLLPNKKVREKRKSLYVNHLTHIAESKQHPSGPMRRKYSSCSTIFLDDSTVSQPNLKYTIKCVALAIYYHIKNRNVDGRMLLDIFDEKLHPLSKSEVPSDYDKHDPEQKQIYRFVRTLFSAAQLTAECAIVTLVYLERLLTYAEIDICPANWKRIVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNELERQFLELLQFNINVPSSVYAKYYFDLRSLSEANNLSFPLEPLSRDKAQKLEAISRLCDDKYKDLRKAAKKRSVSADNLSVVRWSPAIIS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0009620 (response to fungus), GO:0043207 (response to external biotic stimulus), GO:0001878 (response to yeast)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:1990234 (transferase complex), GO:0061695 (transferase complex, transferring phosphorus-containing groups), GO:1902911 (protein kinase complex), GO:1902554 (serine/threonine protein kinase complex), GO:0000307 (cyclin-dependent protein kinase holoenzyme complex)
Protein: Krueppel-like factor 8 isoform X1 (A0A8M2BHN8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [245-313]
- IPR013087: Zinc finger C2H2-type (domain) [231-316]
Sequence:
MPSIQIKPEPEEVECMVKQEPLDDCLEPTDLKIKSSPPPLCIISTQHSDADQTEPVDLSLNKPRPSLPIATATSTPANLPPQNITASATIPAVLSQGSILASTQGVGGQQILHVIHTIPSVNMPSKLGQLQTIPVVVQSLPVVYTTVPTDGMATAAITVPLIGSDGRSEGSVRIKPGSTSPVEYQSESDAESGTESGSASFSTQGMEPSINTDVDIPADPDSPDMKRRRVHMCDYDGCNKVYTKSSHLKAHRRIHTGEKPYQCTWEGCTWRFARSDELTRHFRKHTGIKPFRCTDCDRSFSRSDHLALHRRRHVMM
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003690 (double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0007389 (pattern specification process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0021549 (cerebellum development), GO:0021575 (hindbrain morphogenesis), GO:0021697 (cerebellar cortex formation), GO:0003002 (regionalization), GO:0060322 (head development), GO:0030154 (cell differentiation), GO:0021692 (cerebellar Purkinje cell layer morphogenesis), GO:0021694 (cerebellar Purkinje cell layer formation), GO:0048731 (system development), GO:0021681 (cerebellar granular layer development), GO:0048513 (animal organ development), GO:0030902 (hindbrain development), GO:0021683 (cerebellar granular layer morphogenesis), GO:0009799 (specification of symmetry), GO:0021695 (cerebellar cortex development), GO:0021587 (cerebellum morphogenesis), GO:0022037 (metencephalon development), GO:0021680 (cerebellar Purkinje cell layer development), GO:0021696 (cerebellar cortex morphogenesis), GO:0007420 (brain development), GO:0009855 (determination of bilateral symmetry), GO:0022008 (neurogenesis), GO:0021533 (cell differentiation in hindbrain), GO:0007399 (nervous system development), GO:0060972 (left/right pattern formation), GO:0021702 (cerebellar Purkinje cell differentiation), GO:0007417 (central nervous system development), GO:0030182 (neuron differentiation), GO:0007368 (determination of left/right symmetry), GO:0048699 (generation of neurons), GO:0021953 (central nervous system neuron differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Peroxisomal multifunctional enzyme type 2 isoform X1 (A0A8M9PQQ8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Peroxisome
InterPro domains:
- IPR002539: MaoC-like dehydratase domain (domain) [477-585]
- IPR051687: Peroxisomal Beta-Oxidation Enzymes (family) [5-603]
- IPR002347: Short-chain dehydrogenase/reductase SDR (family) [10-196]
- IPR057326: Ketoreductase domain (domain) [10-184]
- IPR036527: SCP2 sterol-binding domain superfamily (homologous_superfamily) [633-749]
- IPR029069: HotDog domain superfamily (homologous_superfamily) [322-595]
- IPR003033: SCP2 sterol-binding domain (domain) [643-744]
- IPR020904: Short-chain dehydrogenase/reductase, conserved site (conserved_site) [151-179]
- IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [5-294]
- IPR054357: Peroxisomal multifunctional enzyme type 2-like, N-terminal domain (domain) [332-458]
Sequence:
MSVPLRFDGKVVLVTGAGGGLGREYALAFGQRGAAVIVNDLGGDIKGGGKSSAAADKVVEEIRAAGGKAVANYDSVEDGEKLIQTALDAFGRIDVVVNNAGILRDRSFARTSDVDWDLIQRVHLRGSFLVTRAAWNHMKQQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLLGLANTLAIEGQKYNIHCNTIAPTAGSRLTETVMPPDLVQSLKAEYVAPLVLWLCHESCQENSGLFEVGAGWIGKLRWERSLGRIVRQKSECVTPEAVRDAWRDICDFTNATKPASIQESLQTLVEVLSRVEDERKIGANPTAVATNPAQAIGHVLPDMTFTHTHMNCILYALGVGVSSRDPQQLQFLYEGHTHFSCLPTFGVIPAQGALLGLGSIPGLDIDFTRLLHGEQYLELYKPLPTSGTLTSRATVADVLDKGSGMLILLDVHTYSEQELLCYNQFSVFIVGSGGFGGKRVSQKAVAPAAPPDRPADAVVVEETSRDQAALYRLSGDWNPLHIDPNFAAMGGFQSPILHGLCSFGFAARHVLKQFAGNDVSRFKAMKVRFVKPVYPGQSLQTEMWKENSRVHIQCTVKESGAVVLSGAYIDLHPAASVNTGPPQARTHTHTYTHTHTHTDAEGVFAPQTELQSDLVFAEIERRIKDSGEELVKKVNAVFGWEITTDGETRRHWTVDLKTGRGSVQRAAAKADVTFTVSDQDFMEVVMGKLNPQKAFFAGKLKVKGNIMLSQKLEAVLKDQARL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009790 (embryo development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0022008 (neurogenesis), GO:0048568 (embryonic organ development), GO:0007399 (nervous system development), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0048699 (generation of neurons)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0042579 (microbody), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005777 (peroxisome)