Protein: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X7 (A0A8M6YX22)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Peripheral membrane protein
InterPro domains:
- IPR020590: Guanylate kinase, conserved site (conserved_site) [145-162]
- IPR041489: PDZ domain 6 (domain) [454-510]
- IPR008145: Guanylate kinase/L-type calcium channel beta subunit (domain) [111-289]
- IPR008144: Guanylate kinase-like domain (domain) [113-189]
- IPR001202: WW domain (domain) [304-383]
- IPR036034: PDZ superfamily (homologous_superfamily) [7-1259]
- IPR001478: PDZ domain (domain) [27-1257]
- IPR036020: WW domain superfamily (homologous_superfamily) [301-384]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [129-276]
Sequence:
MAVVLSTTSNMSKSLKKKSHWTNRVHEVVLSRGPSGDLGFELQGGAENGQFPVIGEVKPDRRKLQQDELLLEVNDTPVAGLTIRDVWAVVRHCKDPVRFKCVKQGGVVDKDLRQYLNLRFQKGSLDHELQQIIRDNLYLRTVPCTTRQPREGEVPGVDYNFVTVERFVELERSGALLESGTYEDNYYGTPKPPAEPSPLLLNVAEQLLPGATPTSQGKRRRNKSVSNMEKAGIEPPEEEEEERPVINGNGVAITPESSEHEDKSTDASGEMATTCPSETSTDAPKEDTEPPKSPPKPDENDELGPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDPIYGTYYVDHINRRTQFENPVLEAKRRLQHQQQMQSQGLSSLPLPAVYREKPLFTRDPTQLKGSFLSTPLQKSNMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMATGDVIVYINDVCVLGTTHADVVKLFQSVPIGQSVTLVLCRGYPLPYDPEDAANTLLSPLGLIDRPLLVNGRNSYDSYMEYISRTARFVDPLQTTMVQPHPGDTHLDAGPLEDSVSMASSGAAGGELLTINMVKGADGFGFTIADSNGGQRVKQILEAQGCPGLCEGDLIVEINQQPALTLSHTQVVELLKECPIGTEATLVIQRGGTGHFSPWKTTKQVLEHWDPLSSPTTSLSVHALPHSAPYLHWPSGPEFDLAKPDPYDLYEKSRAIYENRQPGLPRASLPADPSAEFQEVEVHLRRQKSGFGFRILGGEEPGQPILIGAIIEKSPADKDGRLRPGDELISVDGIVVAGKPHRYVIDLMHGAARTGQVKLTVRRRVQPTGEPFPENGRSPGSTQHSSPRSDFNSRMFCNNSAPSQNSAPSTTGSSPPDTAANQNAQPNDVSIQRKETEGFGFVIISSLNRPETAAAAAVPHKIGRIIEGSPADHCGKLKVGDRILAVNNQSIVNMPHADIVKLIKDAGLSVTLRIIPQEETNSTPSAGSSEKQSPMAQPSPVCQPNTVNQTGAAPLANSNAQQNSAPQPSPIKQPISEAQPSLVTQNSPANHPSSVTQQNPQTQPVQTYSHDSSYRSEVKARQDVKPDIRQPFTDYRQPPVDYRHPPVADYRQPPTLDYRHPPLLDYRPLPADPRTFPLPDYRMPQDFDFFTVELEKGMKGFGFSIRGGREYKMDLFVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIKSGGRRVRLLLKRGTGQVPEYGMVSSSLSMCMKSDNHGSPYFFLMGHPKDTQIVPPPGMLTLQPPQVCRK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0072006 (nephron development), GO:0032835 (glomerulus development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0072001 (renal system development), GO:0039021 (pronephric glomerulus development), GO:0001822 (kidney development), GO:0039019 (pronephric nephron development), GO:0048793 (pronephros development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0043229 (intracellular organelle), GO:0070161 (anchoring junction), GO:0043227 (membrane-bounded organelle), GO:0005911 (cell-cell junction), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus), GO:0005912 (adherens junction)