Protein: B cell linker (Q2MD54)
Organism: Homo sapiens (Human)
InterPro domains:
- IPR051751: Immunoreceptor signaling adapters (family) [36-342]
- IPR036860: SH2 domain superfamily (homologous_superfamily) [307-365]
Sequence:
MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKYFGSVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKVS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0060090 (molecular adaptor activity), GO:0008289 (lipid binding), GO:0030674 (protein-macromolecule adaptor activity), GO:0005515 (protein binding), GO:0035591 (signaling adaptor activity), GO:0005102 (signaling receptor binding), GO:0019904 (protein domain specific binding), GO:0019899 (enzyme binding), GO:0042169 (SH2 domain binding), GO:0043274 (phospholipase binding), GO:0019900 (kinase binding), GO:0030159 (signaling receptor complex adaptor activity), GO:0030971 (receptor tyrosine kinase binding), GO:0005068 (transmembrane receptor protein tyrosine kinase adaptor activity), GO:0019901 (protein kinase binding), GO:1990782 (protein tyrosine kinase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0048584 (positive regulation of response to stimulus), GO:0006955 (immune response), GO:0002684 (positive regulation of immune system process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0051716 (cellular response to stimulus), GO:0002682 (regulation of immune system process), GO:0006950 (response to stress), GO:0002253 (activation of immune response), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0002764 (immune response-regulating signaling pathway), GO:0050776 (regulation of immune response), GO:0002757 (immune response-activating signaling pathway), GO:0035556 (intracellular signal transduction), GO:0006959 (humoral immune response), GO:0006952 (defense response), GO:0050778 (positive regulation of immune response), GO:0007166 (cell surface receptor signaling pathway), GO:0002429 (immune response-activating cell surface receptor signaling pathway), GO:0006954 (inflammatory response), GO:0002768 (immune response-regulating cell surface receptor signaling pathway), GO:0050851 (antigen receptor-mediated signaling pathway), GO:0050853 (B cell receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle)