Protein: protein-tyrosine-phosphatase (A0A8M3B8C0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Single- pass type I membrane protein
InterPro domains:
- IPR029021: Protein-tyrosine phosphatase-like (homologous_superfamily) [1495-1789]
- IPR003961: Fibronectin type III (domain) [25-1266]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [106-1263]
- IPR050713: Receptor-type Tyrosine-protein Phosphatases/Ushers (family) [235-1803]
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [110-1261]
- IPR000242: Tyrosine-specific protein phosphatase, PTPase domain (domain) [1521-1784]
- IPR000387: Tyrosine-specific protein phosphatases domain (domain) [1697-1773]
- IPR041201: PTPRJ, transmembrane domain (domain) [1292-1430]
- IPR016130: Protein-tyrosine phosphatase, active site (active_site) [1721-1731]
- IPR003595: Protein-tyrosine phosphatase, catalytic (domain) [1678-1781]
Sequence:
MLRNKAFHAAVWAACGILSTMVVDATECSIEIVKVISSTESIRLTLDNANVKCQYTVSVKDRHTDSKGCRQDREHSKCQIESLDPGTWYHLDVISTLDEKQQSQRAVTLQTRPSAVENLQVSGDANSLDVSWQPGKGKTERYWIVLIDSSGRDSAWNSTVASTATSYTMKGLISGRLYNITVVTEVGELQNSASTQAQTDPGKVSDLVIENLSVRGALKISWTPPSGEWEHIRVALSNGSEVLRNQTVGRTAKEILLSGLNLLPGRVYRMAVSVENGGLANTVIYEGEIGLPPVSQLHVRHSDETSLSALWAHAASSSSRDGYIIQLFQSNTSTVIQTRNLSRDMRECTFNVLTPGRLYDITVTTTAKIIRSSATLQGRTQPLKVNHLKLSNKGSTDSLNASWEKPLGDLDFYHMLLLRDQQTVHNITASANTTSRLLPFLRPGALHKILVTTISGSQTSKLAEAECRTVPAAVSDITVTNSGPDFLNVSWKAAEGDVDNYVVMLKDQEKIVHTLATSKATTECVFRSLVSGRLYSISIATHSGSYRNQTLLQERTKPSTVQNPTAIHSARDDFLKLYWNHASGDYDYYVVTIEHNGTRLQSQKLNRTQSDCAFSDLVPGRLYNLTVSTWSGQHYSAVSIYGRTFPGAVGNLSLTERGGTFLRVSWTSAPGDVDHYELQILFNDTQVSAAVNLSSAIGEHLFSALTPGRLYKIVLSTHSGSYQRAEILEGRTVPSQVQSVHLSAGTADGSLRVSWSSADGDLDFYSVSLFQETHLQDSRRVPKHITQAEFYNLIPGQLYSVTVQSVSGSQTNNSTTTGRTEPSTVTGLRADNELSTHSLLVSWNPAVGVHDGYRLWLLDDGGTNIHNASVPAASRHHLFENLTPGRRYQAHVRTLSGTAESKDVVAEGQTRPSAVSALHVCSNTSSDLSFCWASAVGWVDGYELYLYDRDETLHYHTTLGSDALGWSFTLLQPGTHYKMTITSKSGKLSNQSSVWAHTAPASVPELHVENQGQTDSLLLSWTPAPGGLTGYSVTVDGREQRVGPEVTQVVFHSLVAGRLYLATVQTWSEDLSNSTTAVGRTVPAAPSSVSVSCSGGSVDMKWHVPDTGDYEDFEVTWFPQDTLYISHLRPTQRILEGLHPGRLYNISLRTVSGKRHSPVTYSRPVYHTIRTPPLPAPSIHCFPLSSTSVSCSWTPPHSDYDGFVVQCHRQGSGKAVYTHTLGNHTLSQQFDRLEPFKNYTIYVAVMSGDKQSSTVKNSVITMIDRPPVPPVTVRVNEHSAVITHFTIRFKFNCSWFSDANGAIRYFTIIATESNDVDNGLPEQRHPLPSYLDYRQNHSIKAYQTGYFHSTCAEGSDGKVQVFEINLGAGMKHLGGACKLDPESIQHGSHLCDGPLRSRTSYRLSVRAFTQLFDEENREFPHPLYTDTYLSLPLLTQSAPRSGLTGGITAALFLITMVLALTALLIYRKRAHKIAVQESPVMKMCKWKALPTSQMCLRIRSPVQAANFESHLAKLQSDSSYLLSEEFEGLKDVGRIQTQNAARLLGNRNKNRYNNILPYDSTRVRLSCLEDDPCSDYINANYIPGNNFRWEYIATQGPLPGTKDDFWRMVWEQNVHSLVMVTQCVERGMVKCDHYWPTDSEPLCYGDIVVQLLSEKVFPEWTIRDFKISCESQLRYPRMVRQFHYTIWPDHGVPDTTQSLIQFVRTVRDFINRTNSPGISVVHCSAGVGRTGTFIVLDRALQQLDRNCTVDIYGCVFDLRLHRSYMVQTECQYAYIHQCVRDVLRARKLGCERDNPLFPIYNNII
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0004721 (phosphoprotein phosphatase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0004725 (protein tyrosine phosphatase activity), GO:0016791 (phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0001944 (vasculature development), GO:0072359 (circulatory system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)