Protein: Transmembrane serine protease 2 (A0A7I2V5N2)
Organism: Homo sapiens (Human)
InterPro domains:
- IPR043504: Peptidase S1, PA clan, chymotrypsin-like fold (homologous_superfamily) [179-421]
- IPR009003: Peptidase S1, PA clan (homologous_superfamily) [173-420]
- IPR033116: Serine proteases, trypsin family, serine active site (active_site) [366-377]
- IPR001254: Serine proteases, trypsin domain (domain) [186-420]
- IPR001190: SRCR domain (domain) [80-178]
- IPR001314: Peptidase S1A, chymotrypsin family (family) [213-377]
- IPR018114: Serine proteases, trypsin family, histidine active site (active_site) [223-228]
- IPR036772: SRCR-like domain superfamily (homologous_superfamily) [74-178]
Sequence:
MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSIRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRADG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0017171 (serine hydrolase activity), GO:0008233 (peptidase activity), GO:0008236 (serine-type peptidase activity), GO:0004175 (endopeptidase activity), GO:0004252 (serine-type endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0032501 (multicellular organismal process), GO:0065008 (regulation of biological quality), GO:0071704 (organic substance metabolic process), GO:0003008 (system process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0008217 (regulation of blood pressure), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0010817 (regulation of hormone levels), GO:0043170 (macromolecule metabolic process), GO:0003013 (circulatory system process), GO:0050886 (endocrine process), GO:0006508 (proteolysis), GO:0008015 (blood circulation), GO:0001990 (regulation of systemic arterial blood pressure by hormone), GO:0003073 (regulation of systemic arterial blood pressure), GO:0003081 (regulation of systemic arterial blood pressure by renin-angiotensin), GO:0003044 (regulation of systemic arterial blood pressure mediated by a chemical signal), GO:0001991 (regulation of systemic arterial blood pressure by circulatory renin-angiotensin)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0032501 (multicellular organismal process), GO:0016020 (membrane), GO:0071944 (cell periphery), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)