Protein: protein-tyrosine-phosphatase (A6J821)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR029021: Protein-tyrosine phosphatase-like (homologous_superfamily) [1324-1906]
- IPR013098: Immunoglobulin I-set (domain) [31-214]
- IPR003961: Fibronectin type III (domain) [317-1089]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [26-1097]
- IPR050713: Receptor-type Tyrosine-protein Phosphatases/Ushers (family) [1065-1607]
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [316-1245]
- IPR003598: Immunoglobulin subtype 2 (domain) [43-303]
- IPR045905: Receptor-type tyrosine-protein phosphatase delta, PTPase domain, repeat 1 (domain) [1328-1611]
- IPR000242: Tyrosine-specific protein phosphatase, PTPase domain (domain) [1350-1899]
- IPR000387: Tyrosine-specific protein phosphatases domain (domain) [1526-1888]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [29-322]
- IPR016130: Protein-tyrosine phosphatase, active site (active_site) [1545-1846]
- IPR007110: Immunoglobulin-like domain (domain) [31-312]
- IPR003595: Protein-tyrosine phosphatase, catalytic (domain) [1504-1896]
- IPR003599: Immunoglobulin domain subtype (domain) [37-597]
Sequence:
MPLTSCRMVPVARLLLLLLAFFLYACAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAVAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEEPYKEIDGIATTRYSVAGLSPYSDYEFRVVAVNNIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIASYELVYRDGDQGEEQRITIEPGTSYRLQGLKPNSLYYFRLSARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSLKYAAVDGEDYRPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTDEDVPSGPPRKVEVEAVNATAVKVSWRSPVPNKQHGQIRGYQVHYVKMENGEPKGQPMLKDVMLADAQWEFDDATEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGRPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYIFRLSARNKVGFGEEMVKEISVPEEVPTGFPQNLHSEGTTSTSVQISWQPPVLAERNGVITKYTLLYRDINVPLLPMEHLIVPADTSMTLTGLKSDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPDVPANENIKGYYIIIVPLKKSRGKFIKPWESPDEMELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLAVMDHAESKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKRKRAESESRKSSLPNSKEVPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHYAT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0044877 (protein-containing complex binding), GO:0038023 (signaling receptor activity), GO:0043167 (ion binding), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0004721 (phosphoprotein phosphatase activity), GO:0004888 (transmembrane signaling receptor activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0005102 (signaling receptor binding), GO:0005158 (insulin receptor binding), GO:0043168 (anion binding), GO:0019899 (enzyme binding), GO:0004725 (protein tyrosine phosphatase activity), GO:0042301 (phosphate ion binding), GO:0019900 (kinase binding), GO:0042578 (phosphoric ester hydrolase activity), GO:0019198 (transmembrane receptor protein phosphatase activity), GO:0030971 (receptor tyrosine kinase binding), GO:0016791 (phosphatase activity), GO:0005001 (transmembrane receptor protein tyrosine phosphatase activity), GO:0019901 (protein kinase binding), GO:1990782 (protein tyrosine kinase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0065008 (regulation of biological quality), GO:0071840 (cellular component organization or biogenesis), GO:0007155 (cell adhesion), GO:0050794 (regulation of cellular process), GO:0050803 (regulation of synapse structure or activity), GO:0016043 (cellular component organization), GO:0051128 (regulation of cellular component organization), GO:0098609 (cell-cell adhesion), GO:0044087 (regulation of cellular component biogenesis), GO:0033043 (regulation of organelle organization), GO:0098742 (cell-cell adhesion via plasma-membrane adhesion molecules), GO:0050807 (regulation of synapse organization), GO:0034330 (cell junction organization), GO:1902115 (regulation of organelle assembly), GO:1901888 (regulation of cell junction assembly), GO:0050808 (synapse organization), GO:0099150 (regulation of postsynaptic specialization assembly), GO:0051963 (regulation of synapse assembly), GO:1905874 (regulation of postsynaptic density organization), GO:0099175 (regulation of postsynapse organization), GO:0099560 (synaptic membrane adhesion), GO:0099151 (regulation of postsynaptic density assembly), GO:1904889 (regulation of excitatory synapse assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction), GO:0045202 (synapse), GO:0098978 (glutamatergic synapse)