Protein: LIM/homeobox protein Lhx2 isoform X2 (A0A8M2BEV2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
InterPro domains:
- IPR001781: Zinc finger, LIM-type (domain) [10-134]
- IPR017970: Homeobox, conserved site (conserved_site) [247-270]
- IPR050453: LIM/homeobox transcription factors (family) [6-339]
- IPR001356: Homeodomain (domain) [212-276]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [205-271]
Sequence:
MPSISGDRVALCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFETLIQGDFPTHFNHTDVAPNKGLSSTGPLGLSYYNGVNTVQKGRPRKRKSPGPGADLAAYNAALSCNENDGDPMDRDSQYSSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKASDGSNLAGGTPSGPASEISNASMSPSSTPTTLTDLTNPTMPTVTSVLTSVPGSLDVHECRSPSQSTLTSLF
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0048869 (cellular developmental process), GO:0009628 (response to abiotic stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0042221 (response to chemical), GO:0042330 (taxis), GO:0019222 (regulation of metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0007610 (behavior), GO:0032989 (cellular component morphogenesis), GO:0021675 (nerve development), GO:0021537 (telencephalon development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0009314 (response to radiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0060255 (regulation of macromolecule metabolic process), GO:0000902 (cell morphogenesis), GO:0021536 (diencephalon development), GO:0060322 (head development), GO:0030900 (forebrain development), GO:0021794 (thalamus development), GO:0007632 (visual behavior), GO:0016043 (cellular component organization), GO:0006935 (chemotaxis), GO:0009416 (response to light stimulus), GO:0007634 (optokinetic behavior), GO:0030030 (cell projection organization), GO:0048880 (sensory system development), GO:0097485 (neuron projection guidance), GO:0032990 (cell part morphogenesis), GO:0007423 (sensory organ development), GO:0021545 (cranial nerve development), GO:0010468 (regulation of gene expression), GO:0048666 (neuron development), GO:0007420 (brain development), GO:0022008 (neurogenesis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0007399 (nervous system development), GO:0007417 (central nervous system development), GO:0048858 (cell projection morphogenesis), GO:0030182 (neuron differentiation), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0071632 (optomotor response), GO:0001654 (eye development), GO:0021554 (optic nerve development), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0150063 (visual system development), GO:0007411 (axon guidance), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0048812 (neuron projection morphogenesis), GO:0061564 (axon development), GO:0031290 (retinal ganglion cell axon guidance), GO:0043010 (camera-type eye development), GO:0007409 (axonogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)