Protein: Phosphoinositide phospholipase C (A0A8M9Q8J6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
InterPro domains:
- IPR036964: Ras guanine-nucleotide exchange factor, catalytic domain superfamily (homologous_superfamily) [69-345]
- IPR001711: Phospholipase C, phosphatidylinositol-specific, Y domain (domain) [1297-1412]
- IPR001192: Phosphoinositide phospholipase C family (family) [405-1552]
- IPR046974: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1, EF-hand domain (domain) [755-935]
- IPR001895: Ras guanine-nucleotide exchange factors catalytic domain (domain) [66-351]
- IPR017946: PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily (homologous_superfamily) [948-1421]
- IPR046973: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1, catalytic domain (domain) [948-1399]
- IPR011992: EF-hand domain pair (homologous_superfamily) [765-940]
- IPR000008: C2 domain (domain) [1417-1542]
- IPR028398: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1, RA domain 2 (domain) [1692-1794]
- IPR029071: Ubiquitin-like domain superfamily (homologous_superfamily) [1573-1802]
- IPR015359: Phosphoinositide-specific phospholipase C, EF-hand-like domain (domain) [881-935]
- IPR023578: Ras guanine nucleotide exchange factor domain superfamily (homologous_superfamily) [67-316]
- IPR000159: Ras-associating domain (domain) [1693-1796]
- IPR000909: Phosphatidylinositol-specific phospholipase C, X domain (domain) [949-1098]
- IPR035892: C2 domain superfamily (homologous_superfamily) [1429-1582]
Sequence:
MWLSSSRRCGVKQGASETTTTMKHSHSQRMDYRLLKRQLCSSMANSSILPSAVTGISKELADLRHLIQFPEEIATILTEQEQQLYRRVFPLDYLSFLTRDLGSPECHKRHPHLKASLSAPIMPTQNDNHNTVEDLVTRFNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCSWNMGNYNAVMEFLAGLRSRKVLKMWQFMDQADIETMRGLKDAMAQHESSSEYKKVVSRALNIPGCKVVPFCGVFLKELSEALDGAASIIGLRPSFDSQEDPVEFVTDYNGQQHFLQRLGSDGLHSSDKEATVSNILQTIRSCNRSLEAEEPEERAREITVCPKNSFKDKSRNQKGPGTERVLFSIGDLSDSEGDPLETVKDVVDLQTTEDVRGPFSHGTELIPWYVLSLQPDIHQFLLQGATVIHYDPESHLTARCLLRLQPDNCFLTWCKPHSSCSLYGRARTFMGHPASPDHLHIGQPVHCGLSDGLLDLNVVKAVFMGHPGVDVNYVCLQHKLCNMNPGENGVTLLYGLHTTDNRLLHFVAPKHTARMLHEGLQELLNSIRKIRKFPDQRLQWLRKQYVSLYQEDGRFEGPTLAHAIELFGGRRWNMGTSGPGSASRGAEKNSAQKNSPLGINSNVKKKKKALVRGDSGDGTDDEMTARKTRSCKETLGRRESDALENVEQEEAEDCSTFSQPGPFSLSNNKGQSPGSSSSSSTSSSVASFCTNSSTPTRPHSSPILPTNLKSQPGAWSSRSWHGRGKGCFRGFQDLMISDSIMSFVEFVELFKSFSIRSRKDLKELFDTYAVPCSRSGPESVPLYTTLRIDDKLTGLQPDLDLLTRNGSDLGLFIRTRQQMSENQKQISDAIAAASIVTNGTGVENSSLGVLGLAISQLNDFLVNCQREHLSYDEILSIIQKFEPSSNMRQMGWMSFEGFARFLMDKDNFASKNEESQVNLDELQHPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDGMPVIYHGHTLTTKIPFKDVVEAINRAAFVNSEMPVILSIENHCSLPQQRKMAEIFKMVFGEKLVTKFLFESDFADEPLLPSPLQLRGKILLKNKKLKAHQAPVDILKQKAHQLAHMQAQANNGTVSTTPLGNNDEEEEEEDEYDYDYESLSDADVLNASTASYGQEDNILDDKPEGKSSTEKLQYESNDEMPKRFKKAGSKGKMFDMELGEEFYLPQNEKESRQIAQELSDLVIYCQAIKFPGLSTLSPSGSGRGKDRKSRKSIFGSAPARGSPGEPVTLVRAPGKASLEGIRMNSEDQLCLSPSTSLSSIIRTPKCYHISSVNENAAKRLCRRYSQKLIQHTSCQLLRTYPAATRIDSANPNPLIFWLHGVQLVALNYQTDDLPMQLNAALFEANGHCGFVLKPPVLWDRSCPLYQHFYPLDRDLENMTPTLYTLTIVSGQNVCPGNSNGSPCVEVEVLGMPADSCHFRTKPIHRNTLNPMWNEHFQFHVHFEDLAFLRIAVVENNSSQVTAQRILPLKTLRAGYRHLQLRNLHNEPLEVSSLFMFSRRTEESPTGGPPSASVLFSTEERRSVQQHKVTVHGVPGPEPFTVICVDEFTTAKQLLDSLFPTASFKYMLMEERVSLSKEKKAPQQRPLANDERLLKLIHSWQPEDGYVGRIYLKTREQQNCSEKTSVPLESLEELGSLEDDTFFVQVHDVSPEQPHTVIKAPRYSTAQDIIQQTLSKAKYSLSILSNPNPCDYVLMEELCKDAGGKKSSSAKPCQRVLQDHECVFQAQSRWKGAGKFILKLKEQLAREDKRKGVSFASELRKLTGRSRSVTVNTNSNDTHRSLSLGLKAWMAEGRLGSPRRSQCGDGVSALSGWSLPLLWNWKLHK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0016298 (lipase activity), GO:0042578 (phosphoric ester hydrolase activity), GO:0008081 (phosphoric diester hydrolase activity), GO:0004620 (phospholipase activity), GO:0004629 (phospholipase C activity), GO:0004435 (phosphatidylinositol phospholipase C activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0016043 (cellular component organization), GO:0072006 (nephron development), GO:0032836 (glomerular basement membrane development), GO:0032835 (glomerulus development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0072001 (renal system development), GO:0045229 (external encapsulating structure organization), GO:0043062 (extracellular structure organization), GO:0001822 (kidney development), GO:0030198 (extracellular matrix organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)