Protein: RCG55748 (A0A9K3Y7D4)
Organism: Rattus norvegicus (Rat)
Function: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress
Subcellular location: Secreted
InterPro domains:
- IPR024270: Urocortin II/III (family) [1-164]
- IPR000187: Corticotropin-releasing factor (domain) [123-160]
Sequence:
MLMPTYFLLLLLLLLGGPRTSLSHKFYNAGPVFSCLNTALSEVKKNKLEDVPVLSKKNFGYLPTQDPSGEEEDEQKHIKNKRTFSDAVGGNGGRSIRYRYQSQAQPKGKLYPDKVKNDRGTKFTLSLDVPTNIMNILFNIDKAKNLRAKAAANAQLMAQIGKKK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0051427 (hormone receptor binding), GO:0001664 (G protein-coupled receptor binding), GO:0071855 (neuropeptide receptor binding), GO:0051428 (peptide hormone receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0023056 (positive regulation of signaling), GO:0042221 (response to chemical), GO:0032879 (regulation of localization), GO:0051050 (positive regulation of transport), GO:0065008 (regulation of biological quality), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0006950 (response to stress), GO:0007154 (cell communication), GO:0048522 (positive regulation of cellular process), GO:0001666 (response to hypoxia), GO:1903530 (regulation of secretion by cell), GO:1903829 (positive regulation of protein localization), GO:0051049 (regulation of transport), GO:0051047 (positive regulation of secretion), GO:0046887 (positive regulation of hormone secretion), GO:0060341 (regulation of cellular localization), GO:0070482 (response to oxygen levels), GO:1901700 (response to oxygen-containing compound), GO:0010817 (regulation of hormone levels), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0046883 (regulation of hormone secretion), GO:0009991 (response to extracellular stimulus), GO:0042594 (response to starvation), GO:0010646 (regulation of cell communication), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0042391 (regulation of membrane potential), GO:0010647 (positive regulation of cell communication), GO:0031668 (cellular response to extracellular stimulus), GO:0051222 (positive regulation of protein transport), GO:0071496 (cellular response to external stimulus), GO:0035902 (response to immobilization stress), GO:1903532 (positive regulation of secretion by cell), GO:0071456 (cellular response to hypoxia), GO:0009743 (response to carbohydrate), GO:0097305 (response to alcohol), GO:1901654 (response to ketone), GO:0071453 (cellular response to oxygen levels), GO:1904951 (positive regulation of establishment of protein localization), GO:0070201 (regulation of establishment of protein localization), GO:0002793 (positive regulation of peptide secretion), GO:0048545 (response to steroid hormone), GO:0032880 (regulation of protein localization), GO:0050714 (positive regulation of protein secretion), GO:0051223 (regulation of protein transport), GO:0090276 (regulation of peptide hormone secretion), GO:0090087 (regulation of peptide transport), GO:0033993 (response to lipid), GO:0031667 (response to nutrient levels), GO:0036293 (response to decreased oxygen levels), GO:0045838 (positive regulation of membrane potential), GO:0051046 (regulation of secretion), GO:0090277 (positive regulation of peptide hormone secretion), GO:0014070 (response to organic cyclic compound), GO:0050708 (regulation of protein secretion), GO:0031669 (cellular response to nutrient levels), GO:0032024 (positive regulation of insulin secretion), GO:0050796 (regulation of insulin secretion), GO:0031960 (response to corticosteroid), GO:0034284 (response to monosaccharide), GO:0002791 (regulation of peptide secretion), GO:0036294 (cellular response to decreased oxygen levels), GO:0051412 (response to corticosterone), GO:0051385 (response to mineralocorticoid), GO:0051384 (response to glucocorticoid), GO:0009746 (response to hexose), GO:0009749 (response to glucose)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0150034 (distal axon), GO:0044306 (neuron projection terminus), GO:0042995 (cell projection), GO:0043196 (varicosity), GO:0098793 (presynapse), GO:0044304 (main axon), GO:0030054 (cell junction), GO:0120025 (plasma membrane bounded cell projection), GO:0043679 (axon terminus), GO:0045202 (synapse), GO:0043005 (neuron projection), GO:0030424 (axon)