lokahq/bioreason-rl huggingface dataset:
Protein: RCG27500, isoform CRA_c (F7EX25)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR034562: U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 (domain) [146-225]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [1-225]
- IPR034564: U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 (domain) [6-96]
- IPR000504: RNA recognition motif domain (domain) [7-225]
- IPR035979: RNA-binding domain superfamily (homologous_superfamily) [5-213]
Sequence:
MDIRPNHTIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFKELGSSTNALRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKEKKKEKKKAKTMEQAAAAANKKPGQGTPNSANTQGNAAPNPQVPDYPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENDGQAGAARDALQGFKITPSHAMKITYAKK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0043021 (ribonucleoprotein complex binding), GO:0070990 (snRNP binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:1903311 (regulation of mRNA metabolic process), GO:0050684 (regulation of mRNA processing), GO:0031440 (regulation of mRNA 3'-end processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0140513 (nuclear protein-containing complex), GO:0120114 (Sm-like protein family complex), GO:0030532 (small nuclear ribonucleoprotein complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Kallikrein 6, isoform CRA_a (F7F6H9)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR043504: Peptidase S1, PA clan, chymotrypsin-like fold (homologous_superfamily) [49-245]
- IPR009003: Peptidase S1, PA clan (homologous_superfamily) [7-250]
- IPR033116: Serine proteases, trypsin family, serine active site (active_site) [198-209]
- IPR001254: Serine proteases, trypsin domain (domain) [28-249]
- IPR001314: Peptidase S1A, chymotrypsin family (family) [55-209]
- IPR018114: Serine proteases, trypsin family, histidine active site (active_site) [65-70]
Sequence:
MPTKMLTVKTLALCLILAKSAWSEDQDKVVHGGPCLKNSHPFQAALYTSGHLLCGGVLVGPQWVLTAAHCKKPNLEVYLGKHNLRQTETFQRQISVDRTIVHPRYNPQTHDNDIMMVHLKRPVKFSQRIQPLPLKKDCSEKNPDCQILGWGKMENGEFPDTIQCADVQLVSREECERAYPGKITRSMVCAGDKREGNDSCQGDSGGPLVCGGHLRGIVSWGDMPCGSKEKPGVYTDVCTHIRWIQNIIRNK
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050794 (regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0031344 (regulation of cell projection organization), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0010975 (regulation of neuron projection development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Guanine nucleotide-binding protein subunit gamma (A6K2B2)
Organism: Rattus norvegicus (Rat)
Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction
Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side. Membrane; Lipid-anchor; Cytoplasmic side
InterPro domains:
- IPR015898: G-protein, gamma subunit-like domain (domain) [5-74]
- IPR001770: G-protein, gamma subunit (family) [1-73]
- IPR036284: G-protein gamma-like domain superfamily (homologous_superfamily) [1-74]
Sequence:
MPVINIEDLTEKDKLKMEVDQLKKEVTLERVMVSKCCEEVRDYIEERSREDPLVKGIPEDKNPFKELKGGCVIS
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016462 (pyrophosphatase activity), GO:0017111 (ribonucleoside triphosphate phosphatase activity), GO:0003924 (GTPase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0008219 (cell death), GO:0001666 (response to hypoxia), GO:0012501 (programmed cell death), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0070482 (response to oxygen levels), GO:0071456 (cellular response to hypoxia), GO:0071453 (cellular response to oxygen levels), GO:0036293 (response to decreased oxygen levels), GO:0006915 (apoptotic process), GO:0010657 (muscle cell apoptotic process), GO:0036294 (cellular response to decreased oxygen levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0098552 (side of membrane), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0001750 (photoreceptor outer segment), GO:0001917 (photoreceptor inner segment), GO:1902494 (catalytic complex), GO:0019898 (extrinsic component of membrane), GO:0071944 (cell periphery), GO:0098796 (membrane protein complex), GO:0098797 (plasma membrane protein complex), GO:0019897 (extrinsic component of plasma membrane), GO:0120025 (plasma membrane bounded cell projection), GO:1905360 (GTPase complex), GO:0098562 (cytoplasmic side of membrane), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0009898 (cytoplasmic side of plasma membrane), GO:0043005 (neuron projection), GO:0005834 (heterotrimeric G-protein complex), GO:0005929 (cilium), GO:0031234 (extrinsic component of cytoplasmic side of plasma membrane), GO:0097730 (non-motile cilium), GO:0097733 (photoreceptor cell cilium), GO:0097731 (9+0 non-motile cilium)
Protein: RCG24403, isoform CRA_a (F7FMF4)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR036885: SWIB/MDM2 domain superfamily (homologous_superfamily) [240-330]
- IPR019835: SWIB domain (domain) [246-325]
- IPR003121: SWIB/MDM2 domain (domain) [245-322]
Sequence:
MSPGVQHPPTVVQRPGMPSGARMPHQGAPMGPPGSPYMGSPAVRPGLAPAGMEPARKRAAPPPGQSQAQGQGQPVPTAPARSRSAKRRKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNPAKPDAEDSDGSIASWELRVEGKLLDDPSKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTPTTQETDGFQVKRPGDLSVRCTLLLMLDYQPPQFKLDPRLARLLGLHTQSRSAIVQALWQYVKTNRLQDSHDKEYINGDKYFQQIFDCPRLKFSEIPQRLTGLLLPPDPIVINHVISVDPSDQKKTACYDIDVEVEEPLKGQMSSFLLSTANQQEISALDSKIHETIESINQLKIQRDFMLSFSRDPKGYVQDLLRSQSRDLKVMTDVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQRRQELEQSLVVRNT
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0050793 (regulation of developmental process), GO:0051094 (positive regulation of developmental process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0051726 (regulation of cell cycle), GO:0045597 (positive regulation of cell differentiation), GO:0045595 (regulation of cell differentiation), GO:0090068 (positive regulation of cell cycle process), GO:0010564 (regulation of cell cycle process), GO:0045787 (positive regulation of cell cycle), GO:0051149 (positive regulation of muscle cell differentiation), GO:0007346 (regulation of mitotic cell cycle), GO:0045931 (positive regulation of mitotic cell cycle), GO:1901989 (positive regulation of cell cycle phase transition), GO:0051147 (regulation of muscle cell differentiation), GO:1901987 (regulation of cell cycle phase transition), GO:1902749 (regulation of cell cycle G2/M phase transition), GO:1902751 (positive regulation of cell cycle G2/M phase transition), GO:0051152 (positive regulation of smooth muscle cell differentiation), GO:1901992 (positive regulation of mitotic cell cycle phase transition), GO:1901990 (regulation of mitotic cell cycle phase transition), GO:0051150 (regulation of smooth muscle cell differentiation), GO:0010389 (regulation of G2/M transition of mitotic cell cycle), GO:0010971 (positive regulation of G2/M transition of mitotic cell cycle)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: H/ACA ribonucleoprotein complex subunit 2 (A6HE60)
Organism: Rattus norvegicus (Rat)
Function: Common component of the spliceosome and rRNA processing machinery
Subcellular location: Nucleus, nucleolus
InterPro domains:
- IPR018492: Ribosomal protein eL8/Nhp2 family (family) [60-119]
- IPR004038: Ribosomal protein eL8/eL30/eS12/Gadd45 (domain) [46-138]
- IPR029064: Ribosomal protein eL30-like superfamily (homologous_superfamily) [25-149]
- IPR002415: H/ACA ribonucleoprotein complex, subunit Nhp2-like (family) [33-119]
- IPR050257: Large ribosomal subunit protein eL8/uL1-like (family) [31-144]
Sequence:
MTKIKVVPEESEAQAEGCSEERTYEELLVNLNPIAQPLASRRLTRKLYKCIKKAVKQKQIRRGVKEVQKFVNKGEKGIMVLAGDTLPIEVYCHLPVMCEDQNLPYVYIPSKTDLGAATGSKRPTCVIMVKPHEDYQEAYDKCLEEVQALPTPL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0003006 (developmental process involved in reproduction), GO:0048608 (reproductive structure development), GO:0045137 (development of primary sexual characteristics), GO:0007548 (sex differentiation), GO:0046661 (male sex differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0008406 (gonad development), GO:0046546 (development of primary male sexual characteristics), GO:0061458 (reproductive system development), GO:0008584 (male gonad development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005634 (nucleus)
Protein: Alpha-amylase (A0A8I6A5R3)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR006048: Alpha-amylase/branching enzyme, C-terminal all beta (domain) [435-518]
- IPR017853: Glycoside hydrolase superfamily (homologous_superfamily) [27-424]
- IPR006046: Alpha amylase (family) [83-327]
- IPR031319: Alpha-amylase, C-terminal domain (domain) [432-520]
- IPR013780: Glycosyl hydrolase, all-beta (homologous_superfamily) [429-521]
- IPR006047: Glycosyl hydrolase family 13, catalytic domain (domain) [36-423]
Sequence:
MREYCQHHSRMKFFLLLSLIGLCWAQYDPHTFYGRSSIVHLFEWRWVDIAKECERYLAPNGFGGVQVSPPNENIVVNSPFRPWWERYQPISYKICSRSGNEDEFRDMVNRCNNVGVRIYVDAVINHMCGVGAEAGQSSTCGSYFNPNNRDFPGVPYSGFDFNDGKCKTGSGGIENYNDAAQVRDCRLSGLLDLALEKDYVRTKVADYMNHLIDIGVAGFRLDASKHMWPGDIKAVLDKLHNLNTKWFSEGSKPFIYQEVIDLGGEAVSSNEYFGNGRVTEFKYGAKLGKVLRKWDGEKMAYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGSSILTFWDARLYKMAVGFMLAHPYGFTRVMSSFHWPRYFENGKDVNDWVGPPNNNGATKEVTINSDSTCGNDWVCEHRWRQIRNMVAFRNVVNGQPFANWWDNGSNQVAFGRGNKGFIVFNNDDWDLSTTLQTGLPAGTYCDVISGDKVDGNCTGIKVYVGSDGNAYFSISNSAEDPFIAIHVESKI
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds), GO:0016160 (amylase activity), GO:0004556 (alpha-amylase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:0005975 (carbohydrate metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Unc-84 homolog A (C. elegans), isoform CRA_b (A6K1X3)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR040994: SUN coiled coil domain 2 (domain) [641-699]
- IPR045119: SUN domain-containing protein 1-5 (family) [48-876]
- IPR032680: SUN domain-containing protein 1, N-terminal (domain) [66-380]
- IPR012919: SUN domain (domain) [716-877]
Sequence:
MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHRLEPVFDSPRMSRRSLRLITTTAAYSSGDGQTVDTHISTSRATPAKGRETRTVKQRSASKPAFSINHLSGKGLSSSTSHDSSCSLRSATVLRHPVLDESLIREQTKVDHFWGLDDDGDLKGGNKAATQGNGELAAEVASSNGYTCRDCRMLSARTDALTAHSAVHGPTSRVYSRDRTLRPRGASFYLDRTLWLAKYTSSSFASFIVQLFQVVLMKLNFESETYKLKGYESRAYESQSYETKSHESEAHLGHCGRMTAGELSRVDGESLCDLLVRALRRTRAAGWSVAEAMWSVLWLAVTAPGKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGFSLWGQGNFFSLLPMLNWTAMQPAQRVDNPKDMHRPGPLSPSPPLKVDPMASQWPQESDMGQKIASLSAQCHNHDERLAELTVLLQKLQIRVDQVDDGREGLSLWVKDMVGQHLQEIGSIEPPDAKTDFLTLHHDHEVRLSSLEDVLRKLTEKSEAIQKELEETKLRAGSRDEEQPLLDRVQHLELELNLLKSQLSDWQHLRSSCEQADARIQETVQLMFSEDQPGGSLEWLLQKLSSRFVSKDELQVLLHDLELKLLQNITHHITVTGQAPTSEAIVSAMSQAGISGITEAQAHIIVNNALRLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGVPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPRDFAVYGLETEYQEEGQPLGRFTYDQEGDSLQMFHTLERPDQGFQIVELRVLSNWGHPEYTCLYRFRVHGEPIQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005521 (lamin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0001503 (ossification), GO:0009612 (response to mechanical stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: RCG37772 (A0A9K3Y887)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted
InterPro domains:
- IPR000538: Link domain (domain) [34-132]
- IPR016187: C-type lectin fold (homologous_superfamily) [36-131]
- IPR000859: CUB domain (domain) [135-247]
- IPR052129: Spermadhesin-Link domain-containing protein (family) [2-262]
- IPR035914: Spermadhesin, CUB domain superfamily (homologous_superfamily) [132-247]
- IPR016186: C-type lectin-like/link domain superfamily (homologous_superfamily) [36-131]
Sequence:
MVFLLCLCVLLWEEAHGWGFKNGIFHNSIWLEQAAGVYHREARAGRYKLTYAEAKAVCEYEGGRLATYKQLEAARKIGFHVCAAGWMAKGRVGYPIVKPGPNCGFGKTGIIDYGIRLNRSERWDAYCYNPNAKECGGVFTDPKRIFKSPGFPNEYDDNQVCYWHIRLKYGQRIHLSFLDFDLEHDPGCLADYVEIYDSYDDVHGFVGRYCGDELPEDIISTGNVMTLKFLSDASVTAGGFQIKYVTVDPAPKSNQGKNTTMTGNKKFLAGRFSHL
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0043167 (ion binding), GO:0016787 (hydrolase activity), GO:0097367 (carbohydrate derivative binding), GO:0005539 (glycosaminoglycan binding), GO:0005540 (hyaluronic acid binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0019953 (sexual reproduction), GO:0032504 (multicellular organism reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0040017 (positive regulation of locomotion), GO:0040012 (regulation of locomotion), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0007276 (gamete generation), GO:0030728 (ovulation), GO:2000145 (regulation of cell motility), GO:2000147 (positive regulation of cell motility), GO:0030335 (positive regulation of cell migration), GO:0030334 (regulation of cell migration), GO:0007292 (female gamete generation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Protein kinase, AMP-activated, gamma 2 non-catalytic subunit, isoform CRA_a (A6KJH6)
Organism: Rattus norvegicus (Rat)
InterPro domains:
- IPR046342: CBS domain superfamily (homologous_superfamily) [1-296]
- IPR050511: AMP-activated protein kinase gamma/SDS23 families (family) [1-293]
- IPR000644: CBS domain (domain) [14-301]
Sequence:
MRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFMKQNLDELGIGTYHNIAFIHPNTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCSKLETLETIVDRIVRAEVHRLVVVNEADSIVGIISLSDILQALILTPAGAKQKETETE
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0097367 (carbohydrate derivative binding), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0016740 (transferase activity), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:1901265 (nucleoside phosphate binding), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0043168 (anion binding), GO:0004672 (protein kinase activity), GO:0000166 (nucleotide binding), GO:0043169 (cation binding), GO:0019899 (enzyme binding), GO:0032553 (ribonucleotide binding), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity), GO:0016208 (AMP binding), GO:0019900 (kinase binding), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0032555 (purine ribonucleotide binding), GO:0017076 (purine nucleotide binding), GO:0032559 (adenyl ribonucleotide binding), GO:0004679 (AMP-activated protein kinase activity), GO:0019901 (protein kinase binding), GO:0030554 (adenyl nucleotide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0065009 (regulation of molecular function), GO:0050790 (regulation of catalytic activity)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0140535 (intracellular protein-containing complex), GO:0031588 (nucleotide-activated protein kinase complex), GO:1990234 (transferase complex), GO:0061695 (transferase complex, transferring phosphorus-containing groups), GO:1902911 (protein kinase complex)
Protein: Alpha 2,8-sialyltransferase ST8Sia IV (A0A9K3Y707)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Single- pass type II membrane protein
InterPro domains:
- IPR050943: Glycosyltransferase 29 (Sialyltransferase) (family) [142-451]
- IPR038578: GT29-like superfamiliy (homologous_superfamily) [164-452]
- IPR001675: Glycosyl transferase family 29 (family) [196-442]
Sequence:
MHKVSHLKRNPSPREAAQSDPSPASANCAAGRWAALENRESSTAERPSDLILGSRLHAPFANFRFLPLDYFPKTEPLYQEKVPELGQPGLSRAPKMRSIRKRWTICTISLLLIFYKTKEIARTEEHQETQLIGDGELCLSRSLVNNSDKITRKAGSTIFQHSVQGWKINSSLVLEIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISHDLHSLLPEVSPMKNRRFKTCAVVGNSGILLDSGCGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNKLKVRTAYPSLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCDEIHLYGFWPFPKDLNGKAVKYHYYDDLKYRYFSNASPHRMPLEFKTLNVLHNRGALKLTTGKCMKQ
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0008373 (sialyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0065007 (biological regulation), GO:0048523 (negative regulation of cellular process), GO:0050794 (regulation of cellular process), GO:0030155 (regulation of cell adhesion), GO:0007162 (negative regulation of cell adhesion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0048471 (perinuclear region of cytoplasm), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Alpha globin (A0A9K3Y8D0)
Organism: Rattus norvegicus (Rat)
Function: Involved in oxygen transport from the lung to the various peripheral tissues
InterPro domains:
- IPR002338: Hemoglobin, alpha-type (family) [3-142]
- IPR002339: Hemoglobin, pi (family) [4-116]
- IPR009050: Globin-like superfamily (homologous_superfamily) [2-142]
- IPR012292: Globin/Protoglobin (homologous_superfamily) [2-142]
- IPR050056: Hemoglobin and related oxygen transporters (family) [1-142]
- IPR000971: Globin (domain) [2-142]
Sequence:
MVLSEEDKNNIKKAWVKIGNHAAEIGAETIGRLFIVFPSSKTYFPHFNTSEGSDQVKAHGKKVADALTNAASHLDDLPGALSTLSDLHAHKLRVDPVNFKFLSHCLLVTLASHHPGDFTPAMHASLDKFFASVSTVLTSKYR
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0036094 (small molecule binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0019825 (oxygen binding), GO:0046906 (tetrapyrrole binding), GO:0043177 (organic acid binding), GO:0020037 (heme binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:1901700 (response to oxygen-containing compound), GO:0032355 (response to estradiol), GO:0033993 (response to lipid), GO:0014070 (response to organic cyclic compound)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0005833 (hemoglobin complex)