Protein: RCG34128 (A6HCU0)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Multi- pass membrane protein
InterPro domains:
- IPR016187: C-type lectin fold (homologous_superfamily) [398-533]
- IPR006228: Polycystin cation channel (domain) [97-2722]
- IPR000601: PKD domain (domain) [275-2142]
- IPR000483: Cysteine-rich flanking region, C-terminal (domain) [125-177]
- IPR016186: C-type lectin-like/link domain superfamily (homologous_superfamily) [394-532]
- IPR001024: PLAT/LH2 domain (domain) [3109-3224]
- IPR000372: Leucine-rich repeat N-terminal domain (domain) [32-71]
- IPR000434: Polycystic kidney disease type 1 protein (family) [3066-3678]
- IPR002859: PKD/REJ-like domain (domain) [2165-2608]
- IPR000203: GPS motif (conserved_site) [3002-3051]
- IPR022409: PKD/Chitinase domain (domain) [275-2138]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [275-2137]
- IPR035986: PKD domain superfamily (homologous_superfamily) [243-2140]
- IPR014010: REJ domain (domain) [2140-2827]
- IPR001611: Leucine-rich repeat (repeat) [71-126]
- IPR003591: Leucine-rich repeat, typical subtype (repeat) [90-113]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [31-182]
- IPR036392: PLAT/LH2 domain superfamily (homologous_superfamily) [3110-3214]
- IPR002889: Carbohydrate-binding WSC (domain) [177-271]
- IPR001304: C-type lectin-like (domain) [406-530]
Sequence:
MPPGAPARLALALGLGLWLGALAGDPGRGCGPCPLPCFCSPAPDAACRVNCSGRWLQTLGPSLRIPADATALDLSHNLLQTLDIRLLVNLSGLVELDLSNNRISTLEEGVFANLFNLSEINLSGNPFECNCGLAWLPRWAKEQQVHVVQSEATTCRGPVPLAGRPLLSTPLLDNACGEEYVACLPDNSSGAVAAVPFFFAHQGPLETAACSAFCFSAGEGLAALSEQNQCLCGAGQPSNTSAACSSWCSSILLSFNSACGGPTLLQHTFPASPGAALVGPHGPLASGQPADFHINSPLPISSTCWNFGDGSPEVDMAGPAATHSYVLPGGYHVTVVLTLGAGSALLETEVQVEVAPTVLELVCPSFVHSDESLDLGIRHRGGSALEVTYSILALDKEPAQVVHPLCPSDTEIFPGNGHCYRLVAEKAPWLQAQEQCRTWAGAALAMVDSPAIQHFLVSKVTRSLDVWIGFSSVEGKEGLDPQGEAFSLESCQNWLPGEPHPATEEHCVRLGPAGQCNTDLCSAPHSYVCELRPGGPVGDADNFLLGVSGGGRSGPLQPLAQQGTLQGPLQPVEVMVFPGLSPSQEAFLTAAEFETQELEDPVQLRLQVYRHSREAVAPEGSSELDNSTEPAPKCVPEELWCPGANVCVPFDALCNSHVCINGSASRLGLPRASYTLWKEFFFSVPAGPPTQYLVTLHGQDVPMLPGDLVALQHDAGPGTFLHCPLASSCPGQALYLSTNASDWMTNLPVHLEEAWAGPVCSLQLLLVTEQLTPLLGLGSNPGLQHPGHYEVRATVGNSISRQNLSCSFSVVSPVAGLRVIHPIPLDGHIYVPTNGSILVLQVDSGANATATAHWFGGNVSAPFEDACPPEVDFLKQDCTEEANGTLFSVLVLPRLKEGDHTVEIVAQNGASQANLSLRVTAEEPICGLRAVPSPEARVLQGILVRYSPMVEAGSDVAFRWTIDDKQSLTFHNTVFNVIYQTAAVFKLSLTASNHVSNITVNYNVTVERMNKMHGLWVSAVPAVLPPNATLALTGGVLVDSAVEVAFLWNFGDGEQVLRQFKPPYDESFQVPDPTVAQVLVEHNTTHIYNTPGEYNLTVTVSNTYENLTQQVPVSVRTVLPNVTIGMSSNVLLAGQPITFFPYPLPSADGVLYTWDFGDGSPVLIQSQPVLNHTYSMTGTYRISLEVNNTVSSVAAHVDICVFQELHGLTVYLNQSVEQGAPMVVNASVESGDNITWTFDMGDGTVFTGPEATVEHVYLRAQNFTVTVGATSPAGHLSQSLHVQVFVLEVLRIEPSTCIPTQPSAQIMAHVTGDPAHYLFDWTFGDGSSNVTVHGHPSVTHNFTRSGIFPLALVLSSHVNKAHYFTSICVEPEICNVTLQPERQVVKLGDEAWLVAYPWPPFPYRYTWDFGTEDSIHTQTGGSEVTFIYREPGSYLVIVTVSNNISSTNDSAFVDVQEPVSVTGIRINGSHVLELQQPYLFSAMGNGSPAAYLWELGDGSQHEGPEVTHIYSSTGDFTVRVSGWNEVSRSEAQLNITVKQRVRGLTINASRTVVPLNGSVSFSTLLEVGSDVHYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSAQDSIFIYVLQLIEGLQVVGGDGGCCFPTNYTLQLQAAVRDGTNISYSWTAQQDGGPTLISSGKSFSLTALKASTYYVHLRATNMLGSASANRTIDFVEPVESLILSASPNPAAVNTSLTLGAELAGGSGVVYTWYLEEGLSRETSMPSTTHTFAAPGLHLVRVTAENQLGSVNATIEVAVQAPVGGLSIRTSEPDSIFVAAGSTVPFWGQLAEGTNVTWCWTLPGGSKYSQYIDVRFPAAGHFSLWLNASNAVSWVSAVYNLTVEEPIMNLVLWASSKVVAPGQPVHFQILLAAGSAVTFRLQVGGSIPEVLPSLHFSHSFFRVGDHMVSVQAENHVSRAQAQVRILVLEAIVGLQVPNCCEPGMATGTEKNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGILEIHVRAFNELGGVNLTLVVEVQDIIQYVTLQSGRCFTNRSARFEAATSPSPRRVTYHWDFGDGTPVQETEESWTDHYYLHPGDYRVEVNATNLVSFFVAQATVTVQVLACREPEVEVALPLQVLMRRSQRNYLEAHVDLRNCVSYQTEYRWEVYRTTSCQRPGRMTQMVLPGVDVSRPQLVVPRLALPVGHYCFVFVVSFGDTPLARSIQANVTVAAERLVPIIEGGSYRVWSDTQDLVLDGSKSYDPNLEDGDQTPLNFHWACVASTQSETGGCVLNFGPRGSSVVTIPLERLEAGVEYTFNLIVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGHCHNCSSGSKQGRWAARTFSNKTLMLNENTTSTGSTGMHLVVRPGALHDGEGYIFTLTVLGHSGEEEGCASIRLLPNRPPLGGSCRLFPLESVRGLTTKVHFECTGWRDAEDGGAPLVYALRLKRCHQNYCEDFCIYKGSLSTYGAVLPPGFQPLFVVSLTVVVEDQLGASVVALNRSLTIVLPEPSGNPADLIPWLHSLTASVLPGLLRQADPQHVIEYSLALITVLNEYEQAPDMVSEPNLEQQLRAQMRKNITETLISLRVNTVDDIQQITAALAQCMVSSRELMCRSCLKKMLQKLEGMMRILQAETTEGTLTPTTIADSILNITGDLIHLASLDMQGPQPLELGAEPPSLMVASKAYNLSSALMCILMRSRVLNEEPLTLAGEEIVALGKRADPLSLLCYGKAWGPSCHFSIPEAFSGALSDLSDVVQLILLVDSNPFPFGYISNYTVSTKVASMAFQTQTGTQIPIEQLAAERAITVKVPNNSDQAAQSSHSPVGSTIVQPRASVSAVVTADNSNPQAGLHLRITYTVLNARYLSEEREPYLAVYLHSVSQPNEYNCSASRRISLEVLEGADHRPYTFFIAPGTGTLGRSYYLNLTSHFHWSALEVSVGLYTSLCQYFSEEAMMWRTEGIVPLEETSPSQAVCLTRHLTAFGASLFVPPSHVQFIFPEPSVSINYIVLLTCVICLVTYVIMAMILRKLDQLDVSRVRVIPFCGKGGRFKYEILVKTGWSRGSGTTAHVGIMLYGEDNRSGHRHLDGDRAFHRNSLDIFQIATPQSLGSVWKIRVWHDNKGLSPAWFLQHIIVRDLQSARSTFFLVNDWLSVETEANGGLVEKEVLAANEAALWQFQRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRVQRVTCCVLLLCLFLAANAVWYGVVGDTTYSMGPVSSLMSPSVDTVAIGLVSSVVVYPVYLAVLFLFRMSRSKVSGDQNPTPTGQQALDVDSYLDPSVLDSSLLTLSGLTEAFSGQVKNDLFLEDAKSLVCWPSSEGTLSWPDLLSDPSVMSSTLQRLAQGRPGCMLGSEEDGASLVSPSLPAKYLSASDEDLIHQVLADGANNPDPTQDALIERDLLTSLSSAPGEKTETLILQTMGEKRPPSMGLTWEQSPVTRLSRTGLVEGLRKRLLPTWCAPLAHGLSLLLVAVAVAVSGWIGASFPPSVSVMWLLSSSSSFLASFLGWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSERVPRVRPPHGFALFLAKEEARKVKRLHDMLKSLLVYMLFLLVTLLANYGDASCHGHAYRLQSAIKQELDSQAFLAITRSDEFWPWMSHVLLPYVHGNQSSPELGPPRLRQVRLQEAFCPDPSSSEHMCSATGSLSTSDYGIGWQSVVQNGSETWAYSAPDLLGQEPCSVRRTHPLQPCCGATCCCYTAPRVPCSRPCTGCLQCPPICITATQHRPVSATTHLGVLAALCLILLRG
Predicted GO terms:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0065008 (regulation of biological quality), GO:0007204 (positive regulation of cytosolic calcium ion concentration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0071944 (cell periphery), GO:0016328 (lateral plasma membrane), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle)