TissueGene , Inc. is a Maryland-based biopharmaceutical company with a strong global vision focused on developing a proprietary and innovative suite of regenerative orthopedic therapeutic products . Founded in 1999 , the Company 's primary pipeline is focused on the treatment and regeneration of damaged cartilage , bones , disc and nerves . The Company 's core technology employs a form of cell-mediated gene therapy to deliver well-known therapeutic proteins to localized areas of damaged tissue . The sustained expression of such proteins , along with the cellular matrix it is delivered in , initiates rapid and permanent repair of injured tissue without the need for invasive surgical procedures . The Company has successfully demonstrated the growth of cartilage , bone , nerve and tendons in animals . For more information , please visit www.TissueGene.com .