Columns: No. in series | No. in season | Title | Directed by | Written by | Original air date | Production code | U.S. viewers (million)
105 | 1 | "Exile on Main St." | Phil Sgriccia | Sera Gamble | September24,2010 | 3X6052 | 2.90 | 106 | 2 | "Two and a Half Men" | John Showalter | Adam Glass | October1,2010 | 3X6053 | 2.33 | 107 | 3 | "The Third Man" | Robert Singer | Ben Edlund | October8,2010 | 3X6054 | 2.16 | 108 | 4 | "Weekend at Bobby's" | Jensen Ackles | Andrew Dabb & Daniel Loflin | October15,2010 | 3X6051 | 2.84 | 109 | 5 | "Live Free or TwiHard" | Rod Hardy | Brett Matthews | October22,2010 | 3X6056 | 2.47 | 111 | 7 | "Family Matters" | Guy Bee | Andrew Dabb & Daniel Loflin | November5,2010 | 3X6057 | 2.46 | 112 | 8 | "All Dogs Go to Heaven" | Phil Sgriccia | Adam Glass | November12,2010 | 3X6058 | 2.09 | 113 | 9 | "Clap Your Hands If You Believe..." | John Showalter | Ben Edlund | November19,2010 | 3X6059 | 1.94 | 114 | 10 | "Caged Heat" | Robert Singer | Brett Matthews & Jenny Klein | December3,2010 | 3X6060 | 2.15 | 115 | 11 | "Appointment in Samarra" | Mike Rohl | Sera Gamble & Robert Singer | December10,2010 | 3X6061 | 2.27 | 116 | 12 | "Like a Virgin" | Phil Sgriccia | Adam Glass | February4,2011 | 3X6062 | 2.25 | 117 | 13 | "Unforgiven" | David Barrett | Andrew Dabb & Daniel Loflin | February11,2011 | 3X6063 | 1.97 | 118 | 14 | "Mannequin 3: The Reckoning" | Jeannot Szwarc | Eric Charmelo & Nicole Snyder | February18,2011 | 3X6064 | 2.25 | 119 | 15 | "The French Mistake" | Charles Beeson | Ben Edlund | February25,2011 | 3X6065 | 2.18 | 120 | 16 | "...And Then There Were None" | Mike Rohl | Brett Matthews | March4,2011 | 3X6066 | 2.14 | 121 | 17 | "My Heart Will Go On" | Phil Sgriccia | Eric Charmelo & Nicole Snyder | April15,2011 | 3X6068 | 2.26 | 123 | 19 | "Mommy Dearest" | John Showalter | Adam Glass | April29,2011 | 3X6069 | 2.01 | 124 | 20 | "The Man Who Would Be King" | Ben Edlund | Ben Edlund | May6,2011 | 3X6070 | 2.11 | 125 | 21 | "Let It Bleed" | John Showalter | Sera Gamble | May20,2011 | 3X6071 | 2.02