Columns: No. | # | Title | Directed by | Written by | Patient Portrayer | Original air date | Production code
45 | 1 | "Cindy Plumb" | Ryan Murphy | Ryan Murphy | Kathleen Turner | September5,2006 | 3T5001 | 46 | 2 | "Blu Mondae" | Michael M. Robin | Lyn Greene & Richard Levine | Angela Little | September12,2006 | 3T5002 | 47 | 3 | "Monica Wilder" | Elodie Keene | Brad Falchuk | Jennifer Hall | September19,2006 | 3T5003 | 48 | 4 | "Shari Noble" | Nelson McCormick | Jennifer Salt | Melissa Gilbert | September26,2006 | 3T5004 | 49 | 5 | "Dawn Budge" | Elodie Keene | Hank Chilton | Rosie O'Donnell | October3,2006 | 3T5005 | 50 | 6 | "Faith Wolper, Ph.D" | Sean Jablonski | Sean Jablonski | Brooke Shields | October10,2006 | 3T5006 | 51 | 7 | "Burt Landau" | Charles Haid | Brad Falchuk | Larry Hagman | October17,2006 | 3T5007 | 52 | 8 | "Conor McNamara" | Patrick McKee | Jennifer Salt & Hank Chilton | Spencer Roberts | October24,2006 | 3T5008 | 53 | 9 | "Liz Cruz" | Richard Levine | Lyn Greene & Richard Levine | Roma Maffia | October31,2006 | 3T5009 | 54 | 10 | "Merrill Bobolit" | Charles Haid | Sean Jablonski & Brad Falchuk | Joey Slotnick | November7,2006 | 3T5010 | 55 | 11 | "Conor McNamara, 2026" | Craig Zisk | Ryan Murphy | Stark Sands | November14,2006 | 3T5011 | 56 | 12 | "Diana Lubey" | Charles Haid | Sean Jablonski | Catherine Deneuve | November21,2006 | 3T5012 | 57 | 13 | "Reefer" | Lyn Greene | Lyn Greene & Richard Levine | Charles Haid | November28,2006 | 3T5013 | 58 | 14 | "Willy Ward" | Michael M. Robin | Jennifer Salt | Ronn Lucas | December5,2006 | 3T5014