Columns: No. in series | No. in season | Title | Directed by | Written by | Original air date | U.S. viewers (in millions)
44 | 1 | " Reversals of Fortune " | J. Miller Tobin | Joshua Safran | September14,2009 | 2.55 | 45 | 2 | " The Freshman " | Norman Buckley | Amanda Lasher | September21,2009 | 1.97 | 46 | 3 | " The Lost Boy " | Jean de Segonzac | Robert Hull | September28,2009 | 2.36 | 47 | 4 | "Dan de Fleurette" | Mark Piznarski | John Stephens | October5,2009 | 2.08 | 48 | 5 | "Rufus Getting Married" | Ron Fortunato | Leila Gerstein | October12,2009 | 2.36 | 49 | 6 | " Enough About Eve " | John Stephens | Jake Coburn | October19,2009 | 1.98 | 50 | 7 | "How to Succeed in Bassness" | Joe Lazarov | Sara Goodman | October26,2009 | 2.31 | 51 | 8 | "The Grandfather: Part II" | Mark Piznarski | Lenn K. Rosenfeld | November2,2009 | 1.98 | 52 | 9 | " They Shoot Humphreys, Don't They? " | Alison Maclean | Amanda Lasher | November9,2009 | 2.37 | 53 | 10 | " The Last Days of Disco Stick " | Tony Wharmby | Leila Gerstein | November16,2009 | 2.24 | 54 | 11 | "The Treasure of Serena Madre" | Mark Piznarski | Robert Hull & Joshua Safran | November30,2009 | 2.23 | 55 | 12 | " The Debarted " | Jason Ensler | Stephanie Savage | December7,2009 | 2.21 | 56 | 13 | " The Hurt Locket " | Tony Wharmby | Sara Goodman | March8,2010 | 1.74 | 57 | 14 | "The Lady Vanished" | Andrew McCarthy | Amanda Lasher & Robert Hull | March15,2010 | 1.73 | 58 | 15 | "The Sixteen Year Old Virgin" | Wendey Stanzler | Leila Gerstein | March22,2010 | 1.90 | 59 | 16 | "The Empire Strikes Jack" | Joe Lazarov | Jake Coburn | March29,2010 | 1.69 | 60 | 17 | "Inglourious Bassterds" | Jean de Segonzac | Lenn K. Rosenfeld | April5,2010 | 1.74 | 61 | 18 | "The Unblairable Lightness of Being" | Janice Cooke-Leonard | Jeanne Leitenberg | April12,2010 | 1.86 | 62 | 19 | "Dr. Estrangeloved" | Darnell Martin | Robert Hull | April26,2010 | 2.05 | 63 | 20 | "It’s a Dad, Dad, Dad, Dad World" | Jeremiah Chechik | Amanda Lasher | May3,2010 | 1.74 | 64 | 21 | "Ex-Husbands and Wives" | Norman Buckley | Sara Goodman | May10,2010 | 1.79