Alzheimer's disease research
Disease-modifying drug candidates
Columns: Target/Approach | Candidate Name | Trial Phase | Trial Start Date | Expected End Date
Gamma Secretase Modulator/NSAID | MPC-7869 | Phase III | Feb 2005 | May 2008 | Gamma Secretase Inhibitor | LY451039 | Phase III | March 2008 | March 2012 | Antibody to Amyloid-Beta | aab-001 | Phase III | Dec 2007 | Dec 2010 | Metal-Protein Interaction Attenuation | PBT2 | Phase II (completed) | Dec 2006 | Dec 2007 | Fibrilization of Amyloid-Beta | AZD-103 | Phase II | Dec 2007 | May 2010 | Neuroprotection | AL-108 | Phase II (completed) | Jan 2007 | Jan 2008 | Brain Cell Apoptosis Inhibitor | Dimebon | Phase II (completed) | Sept 2006 | Nov 2007 (actual) | Natural Antibodies to A-Beta | IVIg | Phase II (completed) | Feb 2006 | June 2007 | Vaccine to Amyloid-Beta | acc-001 | Phase II | Nov 2007 | Mar 2012 | Notes | Notes | Notes | Notes | Notes