Columns: District | Vacator | Reason for change | Successor | Date successor seated
Iowa 5th | Rush Clark (R) | Died April 29, 1879 | William G. Thompson (R) | October 14, 1879 | Ohio 19th | James A. Garfield (R) | Resigned ????, 1880 | Ezra B. Taylor (R) | December 13, 1880 | Missouri 7th | Alfred M. Lay (D) | Died December 8, 1879 | John F. Philips (D) | January 10, 1880 | New York 32nd | Ray V. Pierce (R) | Resigned September 18, 1880 | Jonathan Scoville (D) | November 12, 1880 | New Hampshire 3rd | Evarts W. Farr (R) | Died November 30, 1880 | Ossian Ray (R) | January 8, 1881 | Florida 2nd | Noble A. Hull (D) | Lost contested election January 22, 1881 | Horatio Bisbee, Jr. (R) | January 22, 1881 | North Carolina 1st | Joseph J. Martin (R) | Lost contested election January 29, 1881 | Jesse J. Yeates (D) | January 29, 1881