2010 Big East Conference football season
Week Two
Columns: Date | Time | Visiting team | Home team | Site | Broadcast | Result | Attendance
September 10 | 7:00pm | No. 23 West Virginia | Marshall | Joan C. Edwards Stadium • Huntington, WV | ESPN2 | W 24–21 OT | 41382 | September 11 | 12:00pm | South Florida | No. 8 Florida | Ben Hill Griffin Stadium • Gainesville, FL | Big East Network | L 14–38 | 90612 | September 11 | 12:00pm | Indiana State | Cincinnati | Nippert Stadium • Cincinnati, OH | FSOHIO | W 40–7 | 30807 | September 11 | 12:00pm | Texas Southern | Connecticut | Rentschler Field • East Hartford, CT | Big East Network | W 62–3 | 37359 | September 11 | 1:00pm | New Hampshire | Pittsburgh | Heinz Field • Pittsburgh, PA | espn3.com | W 38–16 | 50120 | September 11 | 3:30pm | Eastern Kentucky | Louisville | Papa John's Cardinal Stadium • Louisville, KY | Big East Network | W 23–13 | 51427 | September 11 | 7:00pm | Syracuse | Washington | Husky Stadium • Seattle, WA | FSN Northwest | L 20–41 | 62418