Question: How many vacators have October 22, 1808 as date successor seated?
SQL: SELECT COUNT("Vacator") FROM "1-225093-4" WHERE "Date successor seated" = 'October 22, 1808';

Question: What is the date successor seated where Massachusetts 2nd is the district?
SQL: SELECT "Date successor seated" FROM "1-225093-4" WHERE "District" = 'Massachusetts 2nd';

Question: Who is the successor when the reason for change is Seat declared vacant January 2, 1808
SQL: SELECT "Successor" FROM "1-225093-4" WHERE "Reason for change" = 'Seat declared vacant January 2, 1808';

Question: Which district has John Culpepper (F) as the vacator?
SQL: SELECT "District" FROM "1-225093-4" WHERE "Vacator" = 'John Culpepper (F)';