user: Question: what is the average genes when the reference is 2009 and the strain is RKU-1?
Columns: ['Species', 'Strain', 'Type', 'Base Pairs', 'Genes', 'Reference']
Types: ['text', 'text', 'text', 'text', 'real', 'text']
Sample row: ['Fervidobacterium nodosum', 'Rt17-B1', 'Thermotogae', '1,950,000', 1750.0, '2009']
SQL:

assistant: SELECT AVG("Genes") FROM "Table" WHERE "Reference" = '2009' AND "Strain" = 'RKU-1';