Title: A natural product inhibits the initiation of alpha-synuclein aggregation by displacing it from lipid membranes and suppresses its toxicity in cells and in C. elegans.
Authors: Perni, Michele, Galvagnion, Celine, Maltsev, Alexander S, Muller, Martin BD, Challa, Pavan K, Kirkegaard, Julius B, Cascella, Roberta, Limbocker's, Ryan, Sormanni, Pietro, Cremades, Nunilo, Chiti, Fabrizio, Nollen, Ellen AA, Knowles, Tuomas PJ, Vendruscolo, Michele, Bax, Ad, Zasloff, Michael, Dobson, Christopher
Journal: International Worm Meeting
Published: 2017
Affiliations: Chemistry, University of Cambridge, Lensfield Road, CB4 1EW, Cambridge, GB, Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-2560, USA., University of Groningen, University Medical Centre Groningen, European Research Institute for the Biology of Aging, Groningen 9713 AV, The Netherlands., Department of Applied Mathematics and Theoretical Physics, University of Cambridge, Cambridge CB3 0WA, UK., Biocomputation and Complex Systems Physics Insitute (BIFI)-Joint Unit BIFI-IQFR (CSIC), University of Zaragoza, 50018 Zaragoza, Spain, Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence 50134, Italy, MedStar-Georgetown Transplant Institute, Georgetown University School of Medicine, Washington DC 20010, USA.