Title: Ras farnesyltransferase inhibitors suppress the phenotype resulting from an activated ras mutation in Caenorhabditis elegans.
Authors: Hara M, Han M
Journal: Proc Natl Acad Sci U S A
Published: 1995-04-11
Volume: 92
Pages: 3333-7
Keywords: Caenorhabditis elegans drug effects, Caenorhabditis elegans genetics, Caenorhabditis elegans growth and development, Dose Response Relationship, Drug, Genes, Helminth genetics, Genes, ras genetics, Gliotoxins pharmacology, Mutation, Phenotype, Polyenes pharmacology, Protein Isoprenylation drug effects, Signal Transduction drug effects, Transferases antagonists and inhibitors, Vulva drug effects, Vulva growth and development, ras Proteins metabolism
Affiliations: Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder 80309-0347, USA.