Title: The mechanism of action of avermectins in Caenorhabditis elegans: correlation between activation of glutamate-sensitive chloride current, membrane binding, and biological activity.
Authors: Arena JP, Liu KK, Paress PS, Frazier EG, Cully DF, Mrozik H, Schaeffer JM
Journal: J Parasitol
Published: 1995-04
Volume: 81
Pages: 286-94
Keywords: Anthelmintics metabolism, Anthelmintics pharmacology, Antibiotics, Macrolide metabolism, Antibiotics, Macrolide pharmacology, Caenorhabditis elegans drug effects, Caenorhabditis elegans physiology, Chloride Channels drug effects, Drug Synergism, Electrophysiology, Glutamic Acid pharmacology, Ion Channel Gating drug effects, Ivermectin analogs and derivatives, Ivermectin metabolism, Ivermectin pharmacology, Membrane Potentials drug effects
Affiliations: Merck Research Laboratories, Department of Cell Biochemistry and Physiology, Rahway, New Jersey 07065-0900, USA.