Role of Imaging in Complications of Sinusitis

Study Overview
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Brief Summary
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This study aims to assess the diagnostic performance of CT and MRI in the diagnosis of complications of rhinosinusitis in comparison to clinical and operative findings.

Official Title
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Role of Imaging in Complications of Sinusitis.

Conditions
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Rhinosinusitis, Intracranial Extension, Rhinosinusitis Chronic, Rhinosinusitis Acute, Fungal Sinusitis, Allergic Fungal Rhinosinusitis, Invasive Fungal Sinusitis (Diagnosis)

Intervention / Treatment
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* Radiation: Multislice CT scan of the paranasal sinuses.
* Radiation: MRI examination of the paranasal sinuses


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Male and female patients diagnosed as sinusitis with clinically suspected complications through history and physical examination (site, onset, character of pain, constitutional symptoms, duration). Exclusion Criteria: Patients with absolute or relative contraindications for cross sectional imaging including; claustrophobia, metallic implants, pacemaker and prosthetic heart valves for MRI.

Ages Eligible for Study
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Minimum Age: 5 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Participants<br> | Radiation: Multislice CT scan of the paranasal sinuses.<br>* MSCT scan using GE Revolution Evo 128 multidetector elements scanner (GE Healthcare, Chicago, Illinois, United state) , Toshiba Alexion 16 detector elements scanner (Aplio 500, Toshiba Medical Systems, Otawara-shi, Tochigi 324-8550, Japan). Or Canon Aquilion Prime SP 160 -multidetector- row CT scanner (Canon Medical Systems, Tochigi, Japan) Thin slice Axial scans will be taken at 0.625-1.0 mm slice thickness, commencing from the hard palate till above the end of frontal sinuses, coronal and sagittal multiplanar reconstruction images will be obtained.<br>Radiation: MRI examination of the paranasal sinuses<br>* MRI imaging using Philips Achieva 1.5T MRI device (Philips Achieva, Netherlands) or Siemens Magnetom Altea 1.5T MRI device (Siemens Healthineers, Germany) for suspected intracranial and orbital complications.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of different Types of possible complications detected by CT and MRI | To diagnose the diagnostic accuracy of CT and MRI in detection of different types of orbital and intracranial complications. | 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Rhinosinusitis, complicated sinusitis, complications of sinusitis, Magnetic resonance imaging, Computed tompgraphy, MRI, CT