Partnering to Enhance Emerging Adults' Response to Programs

Study Overview
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Brief Summary
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The goal of this clinical trial (CT) is to learn more about emerging adults' and their peers. Here, we will see how co-participating with a peer in health program might impact brain and behavior change over time. Eligible youth will be invited to come in for a Participation Day, during which they and a peer will independently complete questionnaires. With a peer, they will then complete a short health program, and undergo a brain scan (fMRI) while completing activities. Our study team will reach out to each participant individually again 3, 6, and 12 months later to learn about health behaviors over time.

Official Title
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Partnering to Enhance Emerging Adults' Response to Programs (PEER)

Conditions
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Alcohol Use, Unspecified

Intervention / Treatment
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* Behavioral: Motivational Interviewing (MI)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: within the specified age range agree to be contacted for the 3, 6, and 12 month follow ups provide fully informed consent Exclusion Criteria: left-handed evidence of brain injury/illness and/or neurological, neurodevelopmental disorder including psychosis and related medications (e.g., antipsychotics; neuroleptics) loss of consciousness ≥ 2 minutes other fMRI contraindications (e.g., unremovable metal on/in body, pregnant)

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 19 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Motivational Interviewing (MI)<br> | Behavioral: Motivational Interviewing (MI)<br>* Motivational interviewing with peer dyads starts with an open-ended exploration of the dyad's hazardous drinking behavior via personal stories about alcohol use. It includes a values clarification task and age-matched norms along with personalized feedback regarding the dyad's alcohol use. The goal of the session is to engage the dyad in a thoughtful conversation about drinking and the implications it may have on their lives, with an eye to bolstering and supporting inherent drive for behavior change.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Blood oxygen level dependent (BOLD) response to self-talk | Examine changes in brain activation (BOLD response) as a result of participant's own in-session language | Baseline | 
| Blood oxygen level dependent (BOLD) response to dyadic exchange | Examine changes in brain activation (BOLD response) as a result of participants' dyadic in-session language | Baseline | 
| Pearson correlation of self-talk BOLD response percent signal change with youth health behavior assessed with the Timeline Followback | Association of brain response from Outcome 1 with Timeline Followback change over time | 3-, 6-, and 12-months | 
| Pearson correlation of dyadic exchange BOLD response percent signal change with youth health behavior assessed with the Timeline Followback | Association of brain response from Outcome 2 with Timeline Followback change over time | 3-, 6-, and 12-months |