Turning Pattern of Different Body Segments During Turns and Turning Performance

Study Overview
=================
Brief Summary
-----------------
This is a cross-sectional exploratory study. A total of 25 people with PD, 25 young healthy adults, and 25 middle to older adults will be recruited. Axial segment turning pattern and turning performance will be evaluated in two visits using the Vicon 3D motion analysis system, Gaitup, and 3D motion camera. The independent variables are the initiation timing of the head, upper trunk, pelvis, ankle, and foot when turning and the initiation sequence of turning (% turn). The dependent variables are turning performance, including turning velocity, turning steps, turning step length, turning step width), and stance phase (%).

Detailed Description
-----------------
The first aim of the present study is to explore the correlation between axial segment turning pattern and turning performance in people with PD and healthy adults. The second aim is to verify the validity and reliability of 3D motion camera in turning evaluation. A total of 25 people with PD, 25 young healthy adults, and 25 middle to older adults will be recruited. Axial segment turning pattern and turning performance will be evaluated in two visits using the Vicon 3D motion analysis system, Gaitup, and 3D motion camera. The independent variables are the initiation timing of the head, upper trunk, pelvis, ankle, and foot when turning and the initiation sequence of turning (% turn). The dependent variables are turning performance, including turning velocity, turning steps, turning step length, turning step width), and stance phase (%). For the data analysis, the Shapiro-Wilk test will be used to check for normal distribution. Pearson's correlation coefficient or Spearman's rank correlation coefficient will be used to examine the correlations between axial segment initiation timing and turning performance. To verify the validity and reliability, Pearson's correlation coefficient will be used for concurrent criterion validity. Intraclass correlation one-way random model will be used for test-retest reliability, showed with intraclass correlation coefficient and 95% confidence interval. A p-value of less than 0.05 is considered statistically significant.

Official Title
-----------------
Turning Pattern of Different Body Segments During Turns and Turning Performance in Healthy Adults and People With Parkinson's Disease

Conditions
-----------------
Parkinson's Disease

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Able to walk 5 meters without assistance device Able to turn independently Exclusion Criteria: With neurological disorders MMSE< 24 Any systemic and musculoskeletal disturbances or other causes of walking inability

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Young healthy adults<br>1. 20-39 years old | |
| Middle to older healthy adults<br>40-80 years old age-matched with People with Parkinson's disease group | |
| People with Parkinson's disease<br>40-80 years old Diagnosis of idiopathic Parkinson's disease Hoehn and Yahr stage 1-2 | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Initiation timing (sec) | Initiation timing of the head, upper trunk, pelvis, ankle, and foot when turning | Change from baseline at one week | 
| Turning velocity (cm/sec) |  | Change from baseline at one week | 
| Turning steps |  | Change from baseline at one week | 
| Turning step length (cm) |  | Change from baseline at one week | 
| Turning step width (cm) |  | Change from baseline at one week | 
| Stance phase (%) |  | Change from baseline at one week | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Turning, Parkinson's disease, Inter-segmental coordination, En bloc turning, Turning performance