Electrolytes Disturbances in Critically Ill Egyptian Patients

Study Overview
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Brief Summary
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All selected individuals will be subjected to the following: Full medical history taking Full clinical examination, APACHE II score on admission Electrolytes pannel daily on ICU admission Estimate the duration of stay at ICU Also all selected individuals will be sectioned into groups regarding sites of collection (surgical ICU, CCU and medical ICU). All collected individuals will be sectioned regarding electrolytes imbalance into mild, moderate and severe groups

Detailed Description
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Study Procedures: All selected individuals will be suffering from electrolyte imbalance (EI) with the following data will be obtained: o Measurements: Demographic data: age - gender - BMI - electrolytes data on ICU admission Vital data: heart rate - respiratory rate - blood pressure measurement - Oxygen saturation - Urinary output - Temp +/- CVP measurement. Lab.: CBC - Kidney function tests - liver function tests - ABG - levels of serum sodium, potassium, magnesium, phosphorus, ionized calcium and chloride, with maximum 5 mm blood sampling per day. Serum-sodium levels will be corrected for serum-glucose by lowering the sodium concentration by 2.4 mmol/L for every 100 mg/dl increase in glucose. Corrected Sodium = Measured sodium + 0.016 (Serum glucose - 100) A correction formula was also used to calculate albumin-corrected calcium levels (mmol/L) Corrected Calcium = (0.8 (Normal Albumin - Pt's Albumin)) + Serum Ca APACHE II score Comorbidities Complications: AKI- Acute myocardial infarction Duration of ICU stay Duration of hospital stay Outcome (regarding eventual complications: AKI- Acute myocardial infarction)

Official Title
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The Incidence, Risk Factors and Outcomes of Electrolytes Disturbances in Critically Ill Egyptian Patients: A Single-Centre Prospective Cohort Study

Conditions
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Electrolyte Imbalance

Intervention / Treatment
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* Other: electrolytes - serum blood samples


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: - All patients admitted to medical ICU, surgical ICU and CCU suffering from electrolyte imbalance (EI) over 18 years with the comorbid conditions : Hypertension Heart failure Chronic chest diseases Cancers Chronic kidney disease Diabetes mellitus Cardiac dysrhythmias Pneumonia Sepsis Dehydration Critical bones fractures Exclusion Criteria: Patients with Age less than 18 year old Patient or his 1st degree relatives refuse to participate Patients without electrolytes data Current smoking

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: electrolytes - serum blood samples|CBC - Kidney function tests - liver function tests - ABG - levels of serum sodium, potassium, magnesium, phosphorus, ionized calcium and chloride, with maximum 5 mm blood sampling per day|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| impact of electrolytes imbalances for general health status | Laboratory: levels of serum sodium mmol/L, potassium mmol/L, magnesium mg/dl, phosphorus mg/dl, ionized calcium mmol/L and chloride mmol/L, with maximum 5 mm blood sampling per day. Serum-sodium levels will be corrected for serum-glucose by lowering the sodium concentration by 2.4 mmol/L for every 100 mg/dl increase in glucose. Corrected Sodium = Measured sodium + 0.016 (Serum glucose - 100). A correction formula was also used to calculate albumin-corrected calcium levels (mmol/L). Corrected Calcium = (0.8 (Normal Albumin - Pt's Albumin)) + Serum Ca | 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| impact of electrolytes imbalances for hospital stay | calculation of hospital admission days and correlations with records of serum electrolytes results per admission | 1 year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Electrolytes, Egyptian