AI-based Frailty Assessment Tool for Patients Undergoing Cardiac Surgery

Study Overview
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Brief Summary
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The main purpose of this study is to establish a frailty automatic evaluation index AI frailty index based on artificial intelligence multi-modal non-contact monitoring information analysis. At the same time, the study will explore the correlation between ' AI weakness index ' and perioperative and long-term prognosis and quality of life.

Detailed Description
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This is a prospective cohort study. Patients who undergoes elective cardiac surgery will be enrolled. We collect frailty scales, clinical information and multi-modal, non-contact monitoring information during hospitalization. One-year follow-up will be done. The non-contact monitoring information are used to predict the frailty scales to establish and validate an AI-based frailty assessment model AI frailty index. The AI frailty index will be further used to predict perioperative and long-term outcomes.

Official Title
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Frailty Assessment Tool for Patients Undergoing Cardiac Surgery Based on Artificial Intelligence Multimodal Non-contact Monitoring.

Conditions
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Frailty

Intervention / Treatment
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* Other: No intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Elective cardiac surgery Exclusion Criteria: Emergency surgery Age ≤ 18 years The clinical situation is unstable, such as frequent occurrence of coronary ischemia events, unstable heart failure, or acute events leading to severe discomfort symptoms or changes in vital signs Unable to cooperate in completing research data collection due to severe neurological and psychiatric abnormalities or other reasons Duration of postoperative ventilation > 48 hours or inability to obtain scale data on the first day after surgery

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| AI frailty index establishment group<br>Individuals who undergo elective cardiac surgury | Other: No intervention<br>* No intervention<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| One-dimensional matrix vector composed of five frailty scale results | Consisting of five frailty scales: Edmonton frailty scale, FRAIL frailty scale, Fried frailty scale, Clinical frailty scale, and SPPB | Before and after surgery, up to 2 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 30-day adverse events | Including death, readmission, stroke, myocardial infarction, renal insufficiency or renal failure, dialysis, atrial fibrillation, peripheral vascular embolism, bleeding events, heart failure | 30 days post operative | 
| 1-year adverse events | Including death, readmission, stroke, myocardial infarction, renal insufficiency or renal failure, dialysis, atrial fibrillation, peripheral vascular embolism, bleeding events, heart failure | 1 year post operative | 
| EQ-5D score | The score of EQ-5D questionnaire | 1 year post operative | 
| QOR-15 score | The score of QOR-15 questionnaire | 1 year post operative | 
| Edmonton frailty scale score | The Edmonton frailty scale consists of 11 items for a composite score of 0 to 17, and higher scores mean a worse outcome. | 1 year post operative | 
| FRAIL frailty scale score | The FRAIL frailty scale consists of 5 items, with 3 of 5 required to diagnose frailty. | 1 year post operative | 
| Fried frailty scale score | The Fried frailty scale consists of 5 items, with 3 of 5 required to diagnose frailty. | 1 year post operative | 
| Clinical frailty scale score | The Clinical frailty scale is scored 1 to 9 based on a semiquantitative evaluation of the patient's symptoms, mobility, inactivity, exhaustion, and disability for basic activities of daily living and instrumental activities of daily living, and higher scores mean a worse outcome. | 1 year post operative | 
| Short Physical Performance Battery scale score | The Short Physical Performance Battery scale consists of 3 physical tests, with each scored 0 to 4 for a composite score of 0 to 12, and higher scores mean a better outcome. | 1 year post operative | 
| Perioperative adverse events | Including all cause death, stroke, renal insufficiency, deep sternal wound infection, and reoperation | From surgery to discharge, up to 7 days | 
| Area under receiver operating curve (AUC) | Area under receiver operating curve of algorithm in predicting frailty scales and outcomes | At the end of follow-up (1 mouth) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Frailty, Cardiac surgery, Artificial intelligence, Non-contact monitoring