linjc16/ctgov huggingface dataset:
Looking At Bile Duct Cancer Patient Experience Patterns in Medical Trials

Study Overview
=================
Brief Summary
-----------------
Clinical trials can sometimes favor certain demographic groups. Additionally, there is limited research that delves into the factors that influence participation in clinical trials, both positive and negative. The goal is to identify the obstacles and challenges that prevent participation in bile duct cancer clinical trials, as well as the reasons for withdrawal or discontinuation. The insights gained from this study will ultimately benefit those with bile duct cancer who may be invited to participate in medical research in the years to come.

Official Title
-----------------
Prospective Evaluation of Clinical Study Experiences of Patients With Bile Duct Cancer

Conditions
-----------------
Bile Duct Cancer

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age ≥ 18 years Signed written informed consent Patient has been diagnosed with bile duct cancer Exclusion Criteria: Woman pregnant or susceptible to the being Inability to perform regular electronic reporting Inclusion in another investigational clinical trial

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of bile duct cancer patients who decide to enroll in a clinical study |  | 3 months | 
| Rate of bile duct cancer patients who remain in a clinical study to completion |  | 12 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
bile duct, bile duct cancer
Deep Learning for Intelligent Identification of Arrhythmias

Study Overview
=================
Brief Summary
-----------------
This study aims to design and train a deep learning model for the diagnosis of different arrhythmias.

Detailed Description
-----------------
This study aims to retrospectively and prospectively collect routine clinical data such as electrocardiograms from patients with arrhythmias who meet the inclusion and exclusion criteria. Then we will design and train a deep learning model to analyse the electrocardiographic features of the arrhythmias, and identify the types of arrhythmias and evaluate the value of the model for the diagnosis of different arrhythmias.

Official Title
-----------------
Deep Learning for Intelligent Identification of Arrhythmias (ECG-LEARNING): an Investigator-initiated, National Multicenter, Retrospective-prospective, Cohort Study

Conditions
-----------------
Arrhythmia

Intervention / Treatment
-----------------
* Other: Observational


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: For retrospective study: 1.Patients with arrhythmia diagnosed by routine surface 12-lead electrocardiogram or Holter; 2.The type of arrhythmia is diagnosed by intracardiac electrophysiological examination. For prospective study: 1.Patients with arrhythmia diagnosed by routine surface 12-lead electrocardiogram or Holter; 2.Intracardiac electrophysiological examination is planned. Exclusion Criteria: Lack of routine surface 12-lead electrocardiogram or holter data; Lack of intracardiac electrophysiological examination; Patients refused to sign informed consent and refused to participate in the study.

Ages Eligible for Study
-----------------
Minimum Age: 3 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental Group<br>ECG data and clinical data from this group of arrhythmia patients will be used to build a deep learning model. | Other: Observational<br>* No interventions will be given to patients.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| A deep learning model designed to intelligently identify the types of arrhythmia. | Deep learning was used to develop diagnostic models and intelligently identify arrhythmia types. | 1 day after the enrollment. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The sensitivity, specificity and accuracy of the deep learning model | The sensitivity, specificity and accuracy of a deep learning model designed were evaluated by intracardiac electrophysiological examination results to identify patients with arrhythmia from various centers. | 1 day after the enrollment. | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Arrhythmia
The Uncommon Complications of Meckel's Diverticulum

Study Overview
=================
Brief Summary
-----------------
Acas series study was conducted on emergency acute abdomen patients who finally confirmed intraoperatively as Meckel's diverticulum with different complications. Simple perforation to isolated axial torsioned gangrene was observed. The patients signed consent for their cases to be published.

Detailed Description
-----------------
The study was aimed at reporting the rare complications of Meckel's diverticulum, which were diagnosed intraoperatively among acute abdomen patients presented to HFCSH. The patients had different complications ranging from simple isolated perforation to gangrenous Meckel's diverticulum. All of the patients gave their informed written and signed consent for publication.

Official Title
-----------------
The Uncommon Complications of Meckel's Diverticulum: a Single Center Case Series Study and Literature Review

Conditions
-----------------
To Report the Rare Occurrence of Meckel's Diverticulum

Intervention / Treatment
-----------------
* Other: operative intervention


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: all patients diagnosed with complicated meckel's diverticulum Exclusion Criteria: patients who didn't consent

Ages Eligible for Study
-----------------
Minimum Age: 4 Years
Maximum Age: 33 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: operative intervention|all patients were operated after being admitted to surgical ward for acute abdomen|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Outcome upon discharge | outcome of patients with different complications were reported even though there was no death. | 10 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Meckel's diverticulum; isolated torsion; intussusception; acute abdomen; acute appendicitis
Inflammation and Coagulation Factors for Predicting Cerebral Edema After SAH

Study Overview
=================
Brief Summary
-----------------
Explore the role of Inflammation and coagulation factors in cerebrospinal fluid for predicting persistent cerebral edema after subarachnoid hemorrhage

Official Title
-----------------
Inflammation and Coagulation Factors in Cerebrospinal Fluid for Predicting Persistent Cerebral Edema After Subarachnoid Hemorrhage

Conditions
-----------------
Inflammation, Coagulation and Hemorrhagic Disorders, Cerebral Edema

Intervention / Treatment
-----------------
* Diagnostic Test: Inflammatory factors and coagulation factors level in cerebrospinal fluid after subarachnoid hemorrhage


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Subarachnoid hemorrhage patients admitted to our neurosurgery department with modified Fisher Scale 3-4, with a confirmed radiographic diagnosis. Exclusion Criteria: Angiogram-negative patients, patients with a history of trauma or previous brain injury (stroke, hemorrhage, surgery et al. which left associated chronic changes on CT), arteriovenous malformation, radiological data lost, accompany with serious comorbidities before subarachnoid hemorrhage onset (such as coagulation defects, uncontrollable hypertension, and arrhythmia et.al.), initial radiological data performed more than 3 days after SAH onset

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: Inflammatory factors and coagulation factors level in cerebrospinal fluid after subarachnoid hemorrhage|Inflammatory factors and coagulation factors level in cerebrospinal fluid will be tested by ELISA kits.|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cerebral edema after subarachnoid hemorrhage | Cerebral edema after subarachnoid hemorrhage will be determined by the SEBES score. SEBES 0-2 is mild edema; SEBES 3-4 is severe edema. | At 3 and 7days after SAH onset | 
| Outcome at 3 months after subarachnoid hemorrhage | Outcome will be determined by the modified Rankin Score (mRS). mRS 0-2 is favorable outcome; mRS3-5 is poor outcome. | 3 months after subarachnoid hemorrhage |
Implementing the Transcultural Social-Ethical-Care Model -TEC-MED for Older People in the Mediterranean Basin

Study Overview
=================
Brief Summary
-----------------
Implementation of the TEC-MED model of social and health care in the elderly population of the Mediterranean basin through a quasi-experimental trial. Participants will be assigned to the intervention group and will receive comprehensive care and assessment under the TEC-MED care model. Participants in the control group will receive usual care during the data collection phase, but will be offered care under the TEC-MED model at the end of the project.

Official Title
-----------------
Implementing the Transcultural Social-Ethical-Care Model -TEC-MED for Older People in the Mediterranean Basin

Conditions
-----------------
Older People, Care Dependency, Social Exclusion

Intervention / Treatment
-----------------
* Other: Socio-health care


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 60 years or more Living in the Mediterranean Basin countries Exclusion Criteria: None

Ages Eligible for Study
-----------------
Minimum Age: 60 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Supportive Care
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: INTERVENTION GROUP<br>Implementation of socio-health care based on TEC-MED model | Other: Socio-health care<br>* Socio-health care under TEC-MED model and an integral assessment<br>* Other names: TEC-MED care model;|
| No Intervention: CONTROL GROUP<br>No intervention | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Care Dependency Level | Assessment of the care dependency level using INICIARE Scale. The scale measures the care dependency level, framed in three levels: low level, mid level, high level. The expected outcome is to mantain the care dependency level, or low level, from the fisrt assessment to the second. | 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Quality of life level | Assessment of the quality of life level, using the EQ-5D-5L Scale. The scale measures the quality of life level, framed in two levels: low level and high level. The expected outcome is to improve the quality of live level, from the fisrt assessment to the second. | 3 months |
Improving Dietary Habit and Weight Loss in Young Adults With Overweight and Obesity: The Healthy Eating for Young Adults (HEYA) Study

Study Overview
=================
Brief Summary
-----------------
This study aims to examining the effectiveness of a psychoeducational program (Healthy Eating in Young Adults; HEYA) on improving the dietary habits and body composition (e.g. weight and percentage fat mass) in young adults in Singapore.

Official Title
-----------------
Improving Dietary Habit and Weight Loss in Young Adults With Overweight and Obesity: The Healthy Eating for Young Adults (HEYA) Study

Conditions
-----------------
Obesity

Intervention / Treatment
-----------------
* Behavioral: HEYA


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: have a body mass index (BMI) ≥23kg/m2; and are between the ages of 21 and 35 years old; and can understand and read the English language; and use a smartphone that can download apps; and willing to travel to the National University Singapore. Exclusion Criteria: Pregnant or lactating; and Participating in a structured weight loss program; and Planning or receiving pharmacotherapy or bariatric surgery within the next 6 months; and Has existing diagnosed mental disorder besides eating disorders.

Ages Eligible for Study
-----------------
Minimum Age: 21 Years
Maximum Age: 35 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Intervention<br>The HEYA program is a 12-week app-delivered psychoeducational program that comprises of nutrition education, skills training on self-regulation, and weekly feedback. | Behavioral: HEYA<br>* The HEYA program is a 12-week app-delivered psychoeducational program that comprises of nutrition education, skills training on self-regulation, and weekly feedback.<br>|
| No Intervention: Control<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| weight |  | 0,12,24 |
COMPARATIVE ANALYSIS OF THE MORPHO-MECHANICAL PROPERTIES OF RED BLOOD CELLS EXTRACTED FROM DIABETIC PATIENTS WITH AND WITHOUT MICROVASCULAR COMPLICATIONS

Study Overview
=================
Brief Summary
-----------------
The aim of the study is to analyse the biomechanical stiffness of red blood cells extracted from subjects with type I diabetes with and without microvascular complications through a biophysical characterization of red blood cells using microscopy, spectroscopy and scattering measurements. 48 subjects with type 1 diabetes, 24 with and 24 without microvascular complications will be enrolled. From all subjects a single blood sample will be taken to perform the analysis of red blood cells morpho-mechanical properties.

Official Title
-----------------
COMPARATIVE ANALYSIS OF THE MORPHO-MECHANICAL PROPERTIES OF RED BLOOD CELLS EXTRACTED FROM DIABETIC PATIENTS WITH AND WITHOUT MICROVASCULAR COMPLICATIONS

Conditions
-----------------
Diabetes Mellitus, Type 1

Intervention / Treatment
-----------------
* Diagnostic Test: Blood test - atomic force microscopy in the force spectroscopy mode


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Diagnosis of type 1 diabetes for at least 10 years Stable metabolic control (HbA1c <7.5%) for at least 6 months BMI between 18.5 and 30 Kg/m^2 Systolic blood pressure < 140 mmHg and diastolic blood pressure <90 mmHg Exclusion Criteria: Blood pressure higher than 140/90 mmHg Unstable metabolic control (HbA1c >7.5%) BMI > 30 Kg/m^2 or < 18.5 Kg/m^2 Liver failure Concomitant acute infections Uncontrolled thyroid diseases Pregnancy

Ages Eligible for Study
-----------------
Minimum Age: 50 Years
Maximum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Type 1 diabetes with microvascular complications<br> | Diagnostic Test: Blood test - atomic force microscopy in the force spectroscopy mode<br>* A single blood test to be analysed through atomic force microscopy in the force spectroscopy mode<br>|
| Type 1 diabetes without microvascular complications<br> | Diagnostic Test: Blood test - atomic force microscopy in the force spectroscopy mode<br>* A single blood test to be analysed through atomic force microscopy in the force spectroscopy mode<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| In 48 subjects with type 1 diabetes with and without microvascular complications, the average stiffness of red blood cells, measured using atomic force microscope and quantified using Young's modulus, will be measured. | Young's modulus values are obtained using atomic force microscopy | 1 day |
Risk Stratifications for Patients With Palpitations

Study Overview
=================
Brief Summary
-----------------
the aim of the study is to early diagnose and early proper mangment of those patients who have palpitations specially of cardiac origin

Detailed Description
-----------------
Palpitation : are one of the most common presentations to general practice, and while they are usually benign, they may also have life-threatening significance. Palpitations have been estimated to account for 16% of general practice presentations and are the second most common presentation to cardiologists after chest pain.

Official Title
-----------------
Risk Stratifications for Patients Come With Palpitations in Assiut and Suez Canal University Hospitals

Conditions
-----------------
Arrhythmias, Cardiac

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: The present study will be conducted on patients with Palpitations without intently selected certain gender and had 18 years old or more Exclusion Criteria: patients refusing study will be excluded.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mortality | Mortality during 30 days follow up | 30 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Hospital admission | Admission to hospital from the Emergency Department | 0 days | 
| ICU admission | Admission to the Intensive Care Unit or High Dependency Unit from the Emergency Department | 0 days | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
palpitations
the Diameter of Double-lumen Tube Measured by Different Methods

Study Overview
=================
Brief Summary
-----------------
The comparison of the diameter of double-lumen tube at the cuff of endotracheal and endobronchial during the cuff was collapse or inflated as a guide for the selection of the size of double-lumen tube.

Detailed Description
-----------------
The comparison of the diameter of double-lumen tube at the cuff of endotracheal and endobronchial during the cuff was collapse or inflated as a guide for the selection of the size of double-lumen tube.

Official Title
-----------------
The Accuracy of the Diameter of Double-lumen Tube Measured by Different Methods as a Guide to the Size Selection of Double-lumen Tube

Conditions
-----------------
Therapeutic Procedural Complication

Intervention / Treatment
-----------------
* Device: The cuff of endotracheal and endobronchial is collapsed
* Device: The cuff of endotracheal and endobronchial is inflated


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: BMI less than 35 kg/m2 ASA classifications of I-III, Modified Mallampati classification 1 or 2 Under general anesthesia Exclusion Criteria: Age younger than 18 yr or older than 70 yr ASA class IV or V Abnormalities of the heart, brain, liver, lung, kidney and coagulation function

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: The cuff of endotracheal and endobronchial is collapsed<br>The diameter of double-lumen tube at the cuff of endotracheal and endobronchial during the cuff is collapsed | Device: The cuff of endotracheal and endobronchial is collapsed<br>* The diameter of double-lumen tube at the cuff of endotracheal and endobronchial when the cuff is collapsed as the diameter of double-lumen tube and select a double-lumen tube that matches the patient's trachea and bronchial innerdiameter based on this diameter<br>|
| Experimental: The cuff of endotracheal and endobronchial is inflated<br>The diameter of double-lumen tube at the cuff of endotracheal and endobronchial during the cuff is inflated | Device: The cuff of endotracheal and endobronchial is inflated<br>* The diameter of double-lumen tube at the cuff of endotracheal and endobronchial when the cuff is inflated as the diameter of double-lumen tube and select a double-lumen tube that matches the patient's trachea and bronchial innerdiameter based on this diameter<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of complications | Incidence of postoperative hoarseness and throat pain in patients | 12 weeks |