Analysis of Heart Rate Variability After a Physical Exercise Session

Study Overview
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Brief Summary
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Systemic arterial hypertension (SAH) is a multifactorial clinical condition, characterized by sustained elevation of blood pressure levels, contributing to 50% of deaths from cardiovascular disease. The Autonomic Nervous System (ANS) plays a fundamental role in the regulation of Blood Pressure (BP) and is closely associated with Heart Rate (HR). HR changes are called Heart Rate Variability (HRV). In individuals with SAH, HRV indices are reduced compared to normotensive individuals, showing changes in autonomic modulation, thus increasing the risk for cardiovascular events. The objective of this study will be to analyze the Heart Rate Variability in individuals with controlled SAH after a session of aerobic (EA) or resistance (RE) physical exercise.

Detailed Description
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Controlled hypertensive individuals aged between 30 and 59 years will be selected, for convenience, who use the services of the Instituto de Cardiologia do Rio Grande do Sul. Volunteers will be randomly assigned to an EA session (40 minutes on cycle ergometer, 60% of heart rate reserve) or RE (2 exercises for lower limbs and 2 for upper limbs with 4 sets of 12 repetitions at 60% 1-RM) or control group without exercise. HRV data will be collected by ECG (Wincardio USB - Version 11.1.0.0, MICROMED Biotecnologia Ltda, Brasília - DF - Brazil) during 10 minutes before the exercise session, 10 minutes after the exercise session, 1h and 2h post-session . It is expected to estimate results that may demonstrate clarifications about the impact of a physical exercise session on HRV in controlled hypertensive individuals.

Official Title
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Analysis of Heart Rate Variability After One Session of Aerobic or Resistance Physical Exercise in Controlled Hypertensive Individuals: Randomized Clinical Trial

Conditions
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Hypertension

Intervention / Treatment
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* Other: Aerobic Exercise. 1 session of acute exercise
* Other: Resistance Exercise. 1 session of acute exercise
* Other: no exercise


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Controlled Systemic Alterial Hypertension Exclusion Criteria: Diabetes mellitus; heart failure; coronary artery disease; chronic renal failure; body mass index (BMI) ≥ 35 kg/m2; smokers; individuals with injuries to the upper and lower limbs that make the exercise protocol impossible; not using antihypertensive medication and using beta-blocker and/or alpha-blocker medication.

Ages Eligible for Study
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Minimum Age: 30 Years
Maximum Age: 59 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: AE= Aerobic Exercise RE= Resistance Exercise CT= Control (no exercise)
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Aerobic Physical Exercise<br>Cycle ergometer exercise | Other: Resistance Exercise. 1 session of acute exercise<br>* 2 exercises for lower limbs and 2 for upper limbs with 4 sets of 12 repetitions at 60% 1-RM. 40 minutes<br>Other: no exercise<br>* Rest<br>|
| Experimental: Resistance Physical Exercise<br>Exercise with weights | Other: Aerobic Exercise. 1 session of acute exercise<br>* 40 minutes on cycle ergometer, 60% of heart rate reserve<br>Other: no exercise<br>* Rest<br>|
| No Intervention: Control<br>No exercise. Rest | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Heart Rate Variability. | Analysis of heart rate variability with Wincardio Digital ECG. | 4 hours |