Use of Homeopathy in Patients Suffering From Long COVID-19

Study Overview
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Brief Summary
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In some patients, coronavirus (COVID-19) can cause symptoms that last weeks or even months after the infection has gone. The aim of this study was to describe the effect of adjunctive individualized homeopathic treatment delivered to Long-COVID-19 patients with previously confirmed symptomatic SARS-CoV-2 infection.

Detailed Description
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All patients had been tested positive for SARS-CoV-2 before having developed Long-COVID-19 symptoms. Several testing methods were carried out in each patient to analyze a SARS-CoV-2 infection. For a confirmed infection, at least 3 out of these 5 tests had to be positive. Tests for the orthomyxoviruses influenza A and B, human metapneumovirus (hMPV) and paramyxoviruses were negative unless stated otherwise. The homeopathic physician treated all Long-COVID-19 patients by individualized homeopathy. Repertorization of the symptoms of the current pandemic and a search in the current homeopathic literature on COVID-19 was performed using computer program. All available homeopathic medicinal products (HMPs) could be chosen by the treating physician. Modified MONARCH criteria were assessed post hoc by all authors. Deviations were solved by discussion in person. Clinical outcome of case reports was evaluated using the Modified Naranjo Criteria for Homeopathy-Causal Attribution Inventory. Eight points is assumed as the limit for potential correlation between homeopathic therapy and amelioration of the symptoms or healing in chronic cases.

Official Title
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Use of Homeopathy in Patients Suffering From Long COVID-19 (LONGCOVIHOM): A Retrospective Case Series

Conditions
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Adjustment Reaction With Physical Symptoms

Intervention / Treatment
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* Drug: Homeopathic medicines


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Long COVID-19 symptoms following recovery from SARS-CoV-2 infection Exclusion Criteria: Patients not signing informed consent

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 100 Years

Sexes Eligible for Study
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Female

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients treated with individualized homeopathy<br>Patients suffering from symptoms of Long COVID-19 were treated with individualized homeopathy. | Drug: Homeopathic medicines<br>* Globules were administered orally..<br>* Other names: Homeopathic medicinal products;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Modified Naranjo criteria | 10 Naranjo criteria are evaluated, eight points is assumed as the limit for potential correlation between homeopathic therapy and amelioration of the symptoms or healing in chronic cases. | 3 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Complementary therapy, Homeopathy, COVID-19, Long-COVID-19, SARS-CoV-2