linjc16/ctgov huggingface dataset:
Fetal Heart Rate Characterization Using Innovative Advanced Non-invasive Technology

Study Overview
=================
Brief Summary
-----------------
The purpose of the study is to examine the effectiveness and reliability of fetal heart rate monitoring by the Oxitone device. Today, fetal monitoring is carried out with an external approach using a Doppler transducer placed on the mother's abdomen or with an internal approach only after water breaks and during active labor by connecting an electrode to the head of the fetus. Oxyton's technology collects various physiological indicators and calculates an estimation of the fetal pulse. This monitoring method has a wide potential for use as part of pregnancy monitoring and perhaps even during childbirth. Fetal heart rate will be measured in pregnant women in the third trimester of pregnancy with one fetus. The patients will wear the Oxitone device at the same time as Doppler monitoring in the hospital. An analysis of the data will be performed in comparison to the current accepted fetal monitor.

Official Title
-----------------
Fetal Heart Rate Characterization Using Innovative Advanced Non-invasive Technology

Conditions
-----------------
Fetus Pulse Monitoring

Intervention / Treatment
-----------------
* Device: Oxitone 1000M


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Healthy individuals between the age of 18-50 Exclusion Criteria: Clotting disorders, diabetes, currently taking psychotropic medications

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 50 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| pregnant women<br>Healthy women in their third trimester of pregnancy with one fetus | Device: Oxitone 1000M<br>* World's First FDA-cleared Wrist-Sensor Pulse Oximetry Monitor<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| fetus pulse | fetus pulse calculated by a new algorithm | through study completion, an average of 1 year | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
fetus, pulse, monitoring, pregnancy
Study on the Accuracy of Intraocular Lens Calculation Formula

Study Overview
=================
Brief Summary
-----------------
In this study, we will retrospectively collect patients who have performed phacoemulsification combined with intraocular lens implantation in our hospital, collect various preoperative biometric data and postoperative refractive data of patients, conduct statistical analysis, and compare the accuracy of various IOL calculation formulas.

Official Title
-----------------
Study on the Accuracy of Intraocular Lens Calculation Formula

Conditions
-----------------
the Accuracy of Intraocular Lens Calculation Formula

Intervention / Treatment
-----------------
* Other: Several Calculation Formulas of Intraocular Lens


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: (1) Conform to the diagnosis of cataract; (2) No complications occurred during and after operation; (3) Before and after operation, the measurement of ocular biological characteristics and refractive state can be successfully completed; (4) Patients who can be followed up regularly after operation. Exclusion Criteria: (1) Serious intraoperative or postoperative complications; (2) Complicated with other eye diseases unsuitable for intraocular lens implantation; (3) Patients with systemic diseases cannot tolerate surgery; (4) Patients with incomplete follow-up data.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 90 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Several Calculation Formulas of Intraocular Lens|Comparison of the accuracy of several intraocular lens calculation formulas|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mean absolute error | The Friedman test was applied to compare the median absolute error between the formulas after the zeroing of the mean numerical error. Post hoc analysis and Bonferroni correction was performed for multiple comparisons. | 1 week、1 month and 3 months postoperation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Distribution of error within ± 0.25D, ± 0.5D, ± 0.75D,and ± 1.0D | Frequency comparisons were made with the chi-square test | 1 week、1 month and 3 months postoperation |
Muscle Transplantation in Strabismus Surgery

Study Overview
=================
Brief Summary
-----------------
All the patients underwent standard muscle transplantation, where the resected extra stump of lateral or medial rectus muscle was transplanted to the medial or lateral rectus muscle using 6-0 prolene which wasrecessed by a standard recession technique

Official Title
-----------------
Muscle Transplantation for Large Angle Horizontal Strabismus: Esotropia Versus Exotropia

Conditions
-----------------
Strabismus, Noncomitant

Intervention / Treatment
-----------------
* Procedure: muscle transplantation


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with esotropia or exotropia of more than 60 prism dioptre Exclusion Criteria: Muscular paralysis. High myopia. .Dissociated vertical divergence. .Accommodative esotropias. Large vertical deviations associated Alphabetic syndromes previous surgeries in either eye
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: group A<br>15 patients with large angle esotropia | Procedure: muscle transplantation<br>* the resected extra stump of rectus muscle was transplanted to the other horizontal rectus muscle which was recessed by a standard recession technique<br>|
| Active Comparator: group B<br>15 patients with large angle exotropia | Procedure: muscle transplantation<br>* the resected extra stump of rectus muscle was transplanted to the other horizontal rectus muscle which was recessed by a standard recession technique<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Compare the angle of strabismus after muscle transplantation procedure in large angle esotropia with large angle exotropia | the change of angle of strabismus will be assessed pre and post muscle transplantation procedure , the angle of strabismus will be measured pre operative and postoperative after one day using hirschburg test measured by degree | one day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| assess the angle of strabismus after muscle transplantation procedure in large angle esotropia with large angle exotropia | the stability of angle of strabismus will be assessed post muscle transplantation procedure , the angle of strabismus will be measured after six month post operative using hirschburg test measured by degree | six months |
Penicillin Allergy Delabeling Among Surgical Patients

Study Overview
=================
Brief Summary
-----------------
Penicillin allergy testing among surgical patients

Official Title
-----------------
Penicillin Allergy Delabeling Among Surgical Patients

Conditions
-----------------
Penicillin Allergy

Intervention / Treatment
-----------------
* Diagnostic Test: Allergy testing


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: surgical patients with reported penicillin allergy Exclusion Criteria: missing consent
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Allergy testing<br> | Diagnostic Test: Allergy testing<br>* University Medicine Greifswald<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Confirmed penicillin allergy |  | 1 week |
Efficacy of a Deep Cleansing Gel Containing 2% Salicylic Acid, 0.2% Zinc Gluconate and 0.05% Lipohydroxy Acid in the Management of Mild to Moderate Facial Acne

Study Overview
=================
Brief Summary
-----------------
A clinical study with 56 healthy subjects (both sexes) aged between 13 to 25 years old. Subjects enrolled had a minimum of 5 inflammatory lesions (papules, nodules and pustules) and 10 non-inflammatory lesions (open and closed comedones), determined by dermatologist. The clinical evaluation considered in oiliness, shininess and global aspect of the skin too. Instrumental assessment of oiliness and shininess was performed, respectively, by Sebumeter and Sebutape. IThe tested cleanser was used twice daily (morning and evening) during 28 days.

Official Title
-----------------
ASSESSMENT OF CLINICAL, INSTRUMENTAL AND NOTICED EFICACY BY SUBJECTS OF A COSMETIC PRODUCT 12.0417.01.090 UNDER NORMAL CONDITIONS OF USE Study With Dermatological Follow-up Including Instrumental Measurements

Conditions
-----------------
Acne Vulgaris on the Face

Intervention / Treatment
-----------------
* Other: Dermocosmetic


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: subjects aged 13-25 years mild to moderate acne on the face signed informed consent Exclusion Criteria: subjects below 13 years and above 26 years severe acne on the face

Ages Eligible for Study
-----------------
Minimum Age: 13 Years
Maximum Age: 26 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Dermocosmetic|Use of daily cleanser to treat facial acne|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Global lesion count | using GEA scale | baseline | 
| Global lesion count | using GEA scale | Day 28 | 
| Closed comedones | count | baseline | 
| Closed comedones | count | Day 28 | 
| papules | count | baseline | 
| papules | count | Day 28 | 
| skin oiliness | instrumental measurement Sebumeter | baseline | 
| skin oiliness | instrumental measurement Sebumeter | Day 28 | 
| skin sebutape | instrumental measurement Sebumeter | baseline | 
| skin sebutape | instrumental measurement Sebumeter | Day 28 | 
| subject satisfaction | questionnaire | Day 28 |
Helicobacter Pylori Infection in Acute Myocardial Infarction Patients

Study Overview
=================
Brief Summary
-----------------
This study aims to investigate the association between H.Pylori and ACS .

Detailed Description
-----------------
The study is based on show the relationship between H.Pylori infection and Acute Coronary Syndrome . Active H.Pylori infection is common in ACS and may represent a modifiable risk factor for upper gastrointestinal bleeding.

Official Title
-----------------
The Study of Helicobacter Pylori Infection in Acute Myocardial Infarction Patients

Conditions
-----------------
Acute Coronary Syndrome

Intervention / Treatment
-----------------
* Diagnostic Test: Stool Analysis


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: All patients presenting by acute coronary syndrome to Coronary Care Units, Internal Medicine Department, Sohag Faculty of Medicine from 18 . Exclusion Criteria: 1.Patients with Cardiogenic Shock. 2. Renal Impairment.(Creatinine Clearence <60) 3. A known systemic inflammatory condition. 4.They had taken any antibiotics in the previous 1 months. 5.They had taken any proton pump inhibitors in previous 2 weeks. 6.Gastrointestinal Bleeding.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 90 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Acute Coronary Syndrome Patients<br>Stool Analysis will be done for all cases to detect H.pylori Antigen and results will be analysed into infected patients and non infected patients. | Diagnostic Test: Stool Analysis<br>* Stool Analysis to detect H.Pylori Antigen in Stool<br>|
| Chronic Stable Angina Patients<br>Stool Analysis will be done for all cases to detect H.pylori Antigen and results will be analysed into infected patients and non infected patients. | Diagnostic Test: Stool Analysis<br>* Stool Analysis to detect H.Pylori Antigen in Stool<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Comparison of results of H.Pylori antigen with ACS | Analysis of H.Pylori antigen and compare with ECG findings and cardiac enzymes | from the day of admission to the day of disharge of sohag university hospitals |
Outpatient Laparoscopic Radical Prostatectomy

Study Overview
=================
Brief Summary
-----------------
The purpose of the study is to evaluate the incidence of surgery-related complications between Day 0 and Day 30.

Detailed Description
-----------------
This is an observational, prospective, open, non-comparative (single arm), bicentric study. This study is aimed at patients with prostate cancer for whom an ambulatory laparoscopic radical prostatectomy has been validated at a multidisciplinary consultation meeting. The possibility of performing this procedure on an outpatient basis is left to the surgeon's discretion, according to well-defined medical procedure criteria. This cohort is part of the usual care. The study will observe the incidence and describe the type, number, severity, duration and frequency of procedure-related complications that may arise in the first month post-op of ambulatory Laparoscopic Radical Prostatectomy. For this reason, patient follow-up will stop at 1 month after surgery, during a routine follow-up visit.

Official Title
-----------------
Study of Postoperative Complications After Laparoscopic Outpatient Radical Prostatectomy in Patients With Localized Prostate Cancer

Conditions
-----------------
Prostate Cancer

Intervention / Treatment
-----------------
* Procedure: Laparoscopic radical prostatectomy


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Male, age ≥ 18 years; Localized prostate cancer; Validation in a multidisciplinary consultation meeting of curative treatment; Scheduled laparoscopic radical prostatectomy; Patient able to understand the information related to the study, to read the information leaflet and to signify his/her non-opposition or opposition to participating in the study; Membership of a social security scheme; Patient having been informed and having given oral non-opposition. Exclusion Criteria: Surgical emergency; Patient not eligible for ambulatory care; Long-term curative anti-coagulant treatment; Resident more than 100km from the clinic; Home alone the first night; Patient under guardianship, curatorship or deprivation of liberty.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
Male

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| ambulatory patient cohort<br>Patients with prostate cancer for whom an ambulatory laparoscopic radical prostatectomy has been validated at a multidisciplinary consultation meeting. | Procedure: Laparoscopic radical prostatectomy<br>* Prostate cancer may require laparoscopic radical prostatectomy, a surgical procedure performed under general anaesthetic.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of complications | The primary endpoint was the incidence of procedural complications between Day 0 and Day 30. | 30 days |
Effects of Preoperative 3D Printing of Distal Intra-articular Radius Fractures on Quality of Fracture Reduction

Study Overview
=================
Brief Summary
-----------------
The investigators aim to evaluate the effect of a preoperative 3D printed Model (3PAS) of distal intraarticular radius fractures on quality of fracture reduction. Surgical procedure is equal in the 3PAS and in the conventional group. To evaluate the quality of fracture reduction each patient receives a postoperative CAT-scan.

Official Title
-----------------
Effects of Preoperative 3D Printing of Distal Intra-articular Radius Fractures on Quality of Fracture Reduction: a Randomized, Single-blinded, Monocentric Clinical Trial

Conditions
-----------------
Distal Radius Fracture, 3D Printing

Intervention / Treatment
-----------------
* Procedure: Osteosynthesis


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patient older than 18 years Surgery criteria fulfilled Informed consent Intra-articular Fracture of the distal radius (AO 23-B and 23-C) (also including Avulsion of the processus styloideus ulnae AO/OTA 2U3A1.1) in preoperative CAT-Scan Exclusion Criteria: Patient does not want a surgical treatment Patient does not want to participate Positive history for surgery due to injury of the hurt wrist beforehand Positive history for surgery due to injury of the opposite wrist beforehand Additional injuries to the hand and forearm (except distal ulna fracture AO 2U3A1.1) Pregnancy Vulnerable people Distal ulna fracture (except AO 2U3A1.1) Extraarticular radius fracture (AO 23-A) Concomitant injuries which interfere with the planned aftercare (intubated for a long time, additional elbow or shoulder fracture)

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: no 3D model<br> | Procedure: Osteosynthesis<br>* Osteosynthesis of distal radius fractures<br>|
| Other: 3D model<br> | Procedure: Osteosynthesis<br>* Osteosynthesis of distal radius fractures<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Articular step-off of the distal radius joint surface in the postop CAT-scan |  | 6 weeks | 
| Articular gap of the distal radius joint surface in the postop CAT-scan |  | 6 weeks |
Retrospective Study of Radio-induced Toxicities in the Treatment of Lung Cancer With Tomotherapy

Study Overview
=================
Brief Summary
-----------------
Lung cancers treated by Tomotherapy represent between 60 and 100 patients per year at the CHR of Metz-Thionville. Some patients were observed to present acute toxicities during treatment such as dysphagia or esophagitis of CTCAE grade > 2. Beyond well known therapeutic and comorbidities factors, the pathophysiology of these events is largely ruled by a constitutional factor - the enzymatic equipment allowing more or less good repair of the DNA lesions induced by radiotherapy (RT). This equipment is characteristic of each individual, hence the term individual radiosensitivity (IR).The scientific literature is rather poor in data describing the frequency of these toxicities in patients receiving RT for lung cancer. The objective of this study is to describe the frequency of acute and late toxicities after normofractionated radiotherapy of 66 Gy in 33 fractions in patients with small cell or non-small cell lung cancer, stage 2 or 3.

Official Title
-----------------
Retrospective Study of Radio-induced Toxicities in the Treatment of Lung Cancer With Tomotherapy

Conditions
-----------------
Lung Cancer

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: stage II-III non-small cell or small cell lung cancer treated with normo-fractionated radiotherapy of 66Gy in 33 fractions using Tomotherapy Exclusion Criteria: patient who refused to be included in the study.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| late toxicity of radiotherapy | according to CTCAE v5.0 grading | up to 2 years after tomotherapy treatment | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| acute toxicity of radiotherapy | according to CTCAE v5.0 grading | 6 months following tomotherapy treatment | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Tomotherapy, Toxicity