The Effect of UV-C Enriched Foods on Vitamin D Deficiency

Study Overview
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Brief Summary
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This study is an experimental design study in which demographic characteristics, food consumption, biochemical parameters and anthropometric measurements of individuals with low vitamin D levels before and after consuming UV-enriched foods will be examined.

Detailed Description
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It was designed to be applied to individuals with low vitamin D levels working in Fatih Sultan Mehmet Training and Research Hospital who meet the research conditions. n the first phase of the study, demographic information will be recorded by asking demographic information from the people who volunteered to participate in the study and who meet the study criteria by using a questionnaire form and 3-day food consumption record information by face-to-face interview technique; anthropometric measurements of the participants will be taken and baseline blood values will be recorded. At the beginning of the experimental study, individuals will be randomized by computer-assisted randomization into four different groups. Biochemical analyses will be analyzed every two weeks, analyses will be repeated 1 month after the study and the effects of vitamin D enrichment on biochemical parameters will be determined.

Official Title
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The Effect of Consumption of UV-C Enriched Foods on Biochemical Findings in Adults With Vitamin D Deficiency

Conditions
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Vitamin d Deficiency

Intervention / Treatment
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* Other: Vitamin D status


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Working in the hospital Being between the ages of 18 and 65 Not being pregnant or lactating Not taking vitamin D supplements or fish oil in the last 1 month Serum 25(OH)vitamin D value below 30 μg/L No kidney disease, kidney stones, cortisone use, blood thinners Not being in a solarium Not eating fish more than once a week Volunteering to participate in the research Exclusion Criteria:

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Screening
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Forty-eight people aged 18-65 years with serum 25(OH)vitamin D levels below 30 μg/L and who meet the study criteria will be selected for the study. Four groups, 12 per group, will be randomly selected by computer-assisted randomization. Group 1 (UV-C mushroom+normal bread group): Group 2 (UV-C mushroom + UV-C bread group) Group 3 (normal mushroom + normal bread group) Group 4 (normal mushroom + normal bread + supplement group)
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Group 1 (UV-C mushroom+normal bread group)<br>UV-C mushroom+normal bread group | Other: Vitamin D status<br>* Four different groups will be compared with each other in terms of vitamin D effect.<br>|
| Experimental: Group 2 (UV-C mushroom + UV-C bread group)<br>UV-C mushroom + UV-C bread group | Other: Vitamin D status<br>* Four different groups will be compared with each other in terms of vitamin D effect.<br>|
| Experimental: Group 3 (normal mushroom + normal bread group)<br>normal mushroom + normal bread group | Other: Vitamin D status<br>* Four different groups will be compared with each other in terms of vitamin D effect.<br>|
| Experimental: Group 4 (normal mushroom+normal bread+supplemente group)<br>normal mushroom + normal bread + supplement group | Other: Vitamin D status<br>* Four different groups will be compared with each other in terms of vitamin D effect.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Vitamin D values | During study, Vitamin D values are evaluated. | Pre-intervention, through study completion, an average of every two weeks and 1 month after the completion of the intervention | 
| Biochemical parameters | Ca and parathormone are evaluated during the study. | Pre-intervention, through study completion, an average of every two weeks and 1 month after the completion of the intervention | 
| Demographic parameters | Demographic values (age, gender, etc.) are also investigated. | Pre-intervention | 
| Food consumption record | Before starting the study and after the end of study the food consumption of participants are evaluated. | Pre-intervention, through study completion, an average of every two weeks and 1 month after the completion of the intervention |