Spatial Cognition Assessment in Virtual Reality

Study Overview
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Brief Summary
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Unilateral spatial neglect (USN) is a highly-prevalent neuropsychological syndrome following a cerebral stroke characterized by massive impairments in daily life. The evaluation and the rehabilitation of USN encounter many limits whereas immersive virtual reality (VR) could be an efficient tool to go through these limits by imitating an environment of perception and action very close to the real one. The investigators will test a multisensory battery of evaluation based on VR for the diagnostic of USN.

Official Title
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Spatial Cognition Assessment in Virtual Reality

Conditions
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Spatial Neglect

Intervention / Treatment
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* Behavioral: Spatial cognition assessment


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: unilateral right stroke Exclusion Criteria: epilepsy / migraine craniotomy major sensory/motor deficit severe cognitive impairment

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Screening
Intervention Model: Single Group Assignment
Interventional Model Description: 60 patients with right stroke will be included in this study: a group of 30 patients with USN will be compared to a group of 30 patients without USN.
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Spatial cognition assessment<br>A single session of spatial cognition assessment (baseline) will be proposed to participants. This assessment will be based on paper-and-pencil tasks and immersive virtual reality tasks (with an HTC Vive Pro Head-Mounted-Display). The assessment will last around 1 hour. | Behavioral: Spatial cognition assessment<br>* The intervention will be composed of tasks assessing spatial cognition in a real environment (cancellation task, line bisection and baking tray task) and in a virtual environment (cancellation task, line bisection, baking tray task and localization tasks).The Catherine Bergego Scale (questionnaire) will also be used.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Omissions in cancellation tasks | Number and localization in space | Baseline | 
| Deviation in line bisection tasks | Deviation of the bisection from the true center of the lines (in mm) | Baseline | 
| Number of the cubes in each side of space in the Baking Tray Tasks | 16 cubes have to be disposed | Baseline | 
| Detections in the localization tasks | Number and localization in space | Baseline | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Duration of eye fixation in each side of space during VR tasks | Collected thanks to the VR headset | Baseline | 
| Completion time of each task | (in s) | Baseline | 
| Score in the Catherine Bergego Scale (CBS) | Functional assessment scored by the occupational therapists. Minimum: 0 / Maximum: 30 / Higher scores mean a better outcome | Assessed within the same week as Baseline | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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spatial neglect, virtual reality, assessment