The Effect of the Use of Washing Solutions at Different Temperatures Used in Intra-arterial Cannulation

Study Overview
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Brief Summary
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Nowadays, intraarterial catheterization is frequently used as an invasive method for intraoperative blood pressure monitoring and control.The radial artery is frequently used in this procedure and the cannula should be flushed with 2-3 ml of heparinized fluid intermittently to prevent occlusion. During the operation, the ambient temperature is approximately 22-24 C and the patient temperature can be 34-36 C. Since the flushing fluids are also in the environment, they are 22-24 C. The aim of this study is to determine whether the fluids at room temperature cause vasoconstriction in the vessel and cause a change in blood pressure arterial values.

Detailed Description
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The aim of this study is to determine whether room temperature fluids cause vasoconstriction or vasodilatation in the vessel and cause a change in blood pressure arterial values.

Official Title
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Investigation of the Effect of Washing Solutions at Different Temperatures Used in Intra-arterial Cannulation for Invasive Blood Pressure Measurement by Doppler Ultrasonography

Conditions
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Intrarterial Catheterization

Intervention / Treatment
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* Other: intra-arterial flushing
* Other: intra-arterial flushing


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: ASA I-III risk class, Medically undergoing intra-arterial cannulation Being between the ages of 18-70 Exclusion Criteria: Diagnosis of DM Vascular disease, Bleeding diathesis, inotropic drug use

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: room temperature washing solution<br>İntra-arterial flushing with heparinized fluid kept in room air | Other: intra-arterial flushing<br>* The catheter will be flushed to prevent occlusion after radial artery catheterization. intra-arterial flushing with heparinized fluid kept in room air<br>* Other names: group room;|
| Active Comparator: washing solution at patient temperature<br>Intra-arterial flushing with heparinized fluid at patient body temperature | Other: intra-arterial flushing<br>* Intra-arterial flushing with heparinized fluid at patient body temperature<br>* Other names: group patient;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Arterial flow velocities PSV | After flushing performed , peak systolic velocity (PSV) values in the radial artery by Ultrasound doppler method. | 30th seconds after arterial flush | 
| Arterial flow velocities End-diastolic velocity | After flushing performed , end- diastolic velocity (EDV) values in the radial artery by ultrasound doppler method; | 30th seconds after arterial flush | 
| Arterial flow velocities resistive indices | After flushing performed resistive indices (RI) values in the radial artery by ultrasound doppler method. | 30th seconds after arterial flush | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| invasive and non-invasive blood pressure | After flushing performed systolic, diastolic, and average blood pressure values measured | 10th,30th,60th,90th ,120th and 150th seconds |