Three Different Oxygenation Strategies in Bronchoscopy Procedures Under Sedation

Study Overview
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Brief Summary
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The purpose of study aims to determine which of the three different oxygenation strategies, including nasal cannula, modified nasopharyngeal cannula, and HFNO groups, is safer in patients undergoing bronchoscopy under sedation.

Detailed Description
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The patients will be evaluated in the anesthesia polyclinic before the procedure, routine preparation will be made, and written informed consent will be obtained. After being informed about the study and potential risks, all patients who gave written informed consent will be enrolled in the study by recording their demographic information after determining whether they are eligible to participate in the study. In addition, STOP-BANG and FRAIL fragility questionnaires will be administered to the patients. Which oxygenation method should be used which patient will be left to the decision of the Anesthesiologist; The oxygenation tools used in the bronchoscopy unit are nasal cannula, modified nasopharyngeal cannula, and HFNO. When the patients are taken to the procedure room, anesthesia management will be applied by the standard working order of the anesthesia clinic. In addition to non-invasive arterial blood pressure monitoring, 5-channel ECG and pulse oximetry, and standard hemodynamic monitoring, Bispectral Index (BIS) monitoring will be performed. During the process, oxygen saturation will be continuously monitored and the lowest value will be recorded. Interventions made in cases of low oxygen saturation will also be recorded. At the end of the procedure, the patient will be taken to the recovery unit after waking up.

Official Title
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Comparison of Three Different Oxygenation Strategies Consisting of Nasal Cannula, Modified Nasopharyngeal Cannula and HFNO (High Flow Nasal Oxygen) in Bronchoscopy Procedures Under Sedation

Conditions
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Bronchoscopy

Intervention / Treatment
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* Other: different oxygenation methods


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All patients undergoing bronchoscopy Exclusion Criteria: Do not have the ability to read, understand and sign the consent form Pregnancy Contraindications to anesthetic drugs Hemodynamically unstable patients Having a peripheral vascular disease Intubated patients Patients with tracheostomy

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| nasal cannula group<br>Nasal cannula will be used in bronchoscopy procedures in which sedation is applied in this group. | Other: different oxygenation methods<br>* Different oxygenation methods are used in bronchoscopy procedures under sedation.<br>|
| modified nasopharyngeal cannula group<br>In this group, modified nasopharyngeal cannula will be used in bronchoscopy procedures with sedation. | Other: different oxygenation methods<br>* Different oxygenation methods are used in bronchoscopy procedures under sedation.<br>|
| HFNO group<br>HFNO will be used in bronchoscopy procedures in which sedation is applied in this group. | Other: different oxygenation methods<br>* Different oxygenation methods are used in bronchoscopy procedures under sedation.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| desaturation rate during processing | desaturation: oxygen saturation falling below 90%. Oxygen saturation was monitored continuously with a pulse oximeter attached to one of the fingers. It was recorded when oxygen saturation dropped to < 90%. | during the procedure, an average of 1 hour | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| rate of use of the jaw thrust maneuver during the procedure | The chin thrust maneuver is one of the maneuvers used to provide airway patency. The jaw thrust maneuvers performed by the anesthesiologist were recorded in patients who were desaturated during the procedure. | during the procedure, an average of 1 hour | 
| rate of airway usage during the process | The airway that was desaturated during the procedure and used by the anesthesiologist to ensure airway patency was recorded. | during the procedure, an average of 1 hour |