Quantification of Internal Training Load

Study Overview
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Brief Summary
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The aim of this study is to determine whether the distribution of internal load predicts the distribution of muscle hypertrophy among hamstring heads after a 10-week resistance exercise program. The hypothesis is that the distribution of internal muscle load among the hamstring is related to the distribution of muscle hypertrophy.

Detailed Description
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It is well accepted that muscle stress (mechanical and/or metabolic) is the major way to induce muscle hypertrophy. While this link between muscle stress and hypertrophy is pivotal is sport training, prevention and rehabilitation, it remains poorly understood. To date, the only indirect evidence of relationship of muscle stress and muscle hypertrophy is the similar patterns (from independent studies) between muscle damage and hypertrophy within quadriceps (i.e., rectus femoris (RF) > vastus (VL) = vastus medialis VM), hamstring, and triceps surae. However, muscle damage is an indirect proof of muscle mechanical stress. With the quantification of internal muscle load, it is interesting to determine whether the muscle that receives the larger stress exhibits the larger hypertrophy.

Official Title
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Quantification of Internal Training Load: Toward the Prediction of the Distribution of Hypertrophy

Conditions
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Hypertrophy, Resistance Training, Muscle

Intervention / Treatment
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* Other: strength training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: No history of lower limb injury No chronic pathology associated with a long term care Exclusion Criteria: Individual enrolled in a research study

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 25 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Three independent groups : Control (no strengthening) Nordic (strengthening in Nordic Hamstring exercise) Deadlift (strengthening in Deadlift exercise)
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Nordic<br>Training regimens composed of nordic exercise | Other: strength training<br>* Strength training, three times a week, during nine weeks.<br>|
| Experimental: Deadlift<br>Training regimens composed of deadlift exercise | Other: strength training<br>* Strength training, three times a week, during nine weeks.<br>|
| No Intervention: Control<br>Training regimens composed of no exercise | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Muscle volume | Hypertrophy | 10 weeks | 
| Internal training load | Magnitude and onset/offset of muscle activation | 10 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Maximal strength Nordic | Maximal strength during the Nordic exercise | 10 weeks | 
| Maximal strength Deadlift | Maximal strength during the Deadlift exercise | 10 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Muscle volume, Muscle activation, Muscle stress, Muscle mass