Physical Therapy in Pre-cystectomy Patients

Study Overview
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Brief Summary
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This single-site, non-randomized, interventional study evaluates the impact of a physical therapy consultation for patients with bladder cancer scheduled for radical cystectomy (RC). The purpose of this study is to investigate whether consultation with a physical therapist and the development of a personally tailored exercise program in the pre-cystectomy period for patients with bladder cancer will result in reduced post-operative complications, morbidity, length of inpatient stay, improve readmission 30-day and 90-day and improve 90-day mortality. This study will be partially retrospective (pre-implementation of a physical therapy consultation order) and partially prospective.

Official Title
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Assessing the Impact of Physical Therapy in the Pre-cystectomy Pathway in Patients With Bladder Cancer on Patient Outcomes

Conditions
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Bladder Cancer

Intervention / Treatment
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* Other: A personally tailored exercise program


Participation Criteria
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Eligibility Criteria
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In order to participate in this study a subject must meet all of the eligibility criteria outlined below: Inclusion Criteria: Age ≥ 18 years at the time of bladder cancer diagnosis History of bladder cancer Performance of radical cystectomy Exclusion Criteria: 1. No history of bladder cancer or radical cystectomy

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: A personally tailored exercise<br>A personally tailored exercise program will be offered to the participants after the Physical Therapy assessment, before the surgery. | Other: A personally tailored exercise program<br>* A personally tailored exercise program will be offered to the participants after Physical Therapy assessment, before the surgery.<br>* Other names: Exercise;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Thirty-day readmission rates | Thirty-day readmission rates will be defined as the comparison of the number of hospital admission after physical therapy consultation and tailored exercises and historical hospital admission data. | Up to 30 days after the date of cystectomy | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The proportion of individuals who received a physical therapy consultation | The feasibility of implementing a physical therapy consultation and tailored exercise program in the pre-cystectomy treatment pathway will be determined by calculating the proportion of individuals who received a physical therapy consultation in the prospective group. | 1 day (the date of cystectomy) | 
| Ninety-day readmission rates | Ninety-day readmission rates will be defined as the comparison of the number of hospital admission after physical therapy consultation and tailored exercises and historical hospital admission data. | Up to 90 days after the date of cystectomy | 
| Acute care length of stay | Acute care length of stay will be defined as comparing number of hospital day stay after physical therapy consultation and tailored exercises and historical hospital admission data. | Starting to the exercises to up to 90 days after the date of cystectomy | 
| Mortality rates | Mortality rates will be defined as the comparison of the number of subjects who died after physical therapy consultation and tailored exercises and historical hospital admission data. | Up to 90 days after the date of cystectomy | 
| Post-cystectomy complication types and rates | Post-cystectomy complication types and rates will be defined as comparison of the numbers and types of complications after physical therapy consultation with tailored exercises and historical data. | Up to 90 days after the date of cystectomy | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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radical cystectomy, physical therapy, exercise program