linjc16/ctgov huggingface dataset:
Delving Into Borderline Personality Disorder Clinical Trial Experiences

Study Overview
=================
Brief Summary
-----------------
Taking part in medical study usually favors a particular demographic group. But there is limited research available to explain what trial attributes affect the completion of these specific demographic groups. This study will admit a wide range of data on the clinical research experience of borderline personality disorder patients to determine which factors prevail in limiting a patient's ability to join or finish a trial. It will also try to analyze data from the perspective of different demographic groups to check for recurring trends which might yield insights for the sake of future borderline personality disorder patients.

Official Title
-----------------
Uncovering Clinical Trial Engagement Among Individuals With Borderline Personality Disorder

Conditions
-----------------
Borderline Personality Disorder

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Aged ≥ 18 years old Clinical diagnosis of Borderline Personality Disorder Able to comprehend the investigational nature of the protocol and provide informed consent Exclusion Criteria: No diagnosis of Borderline Personality Disorder confirmed Inability to perform regular electronic reporting Patient does not understand, sign, and return consent form

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of patients who decide to enroll in a borderline personality disorder clinical research |  | 3 months | 
| Rate of patients who remain in borderline personality disorder clinical research to trial completion |  | 12 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
borderline personality disorder
Wastewater Surveillance to Boost COVID-19 Vaccine Uptake

Study Overview
=================
Brief Summary
-----------------
The goal of the study is to determine the effect of a communications campaign sharing wastewater surveillance data to influence vaccine uptake in a metropolitan and non-metropolitan environment. The study will be conducted in Onondaga and Cayuga counties in New York State. Individuals of all ages within the selected counties, located in metropolitan and non-metropolitan environments will receive the intervention. The evaluation study design is a comparison-control trial. The primary outcome measure is the proportion of vaccine-eligible individuals in the county that received the COVID-19 vaccine stratified by type of vaccine dosage and age group. Vaccination data will be aggregated to the county by the State Department of Health and shared with the research team. Wastewater data will be pulled from the wastewater surveillance network. A difference in differences analysis will be used to estimate the effect of the intervention on both the outcomes between intervention and comparison groups following the intervention, while adjusting for potential confounding factors.

Official Title
-----------------
Utilizing Wastewater Surveillance Data in a Communications Campaign to Boost Vaccination Uptake in New York State: a Comparison-control Trial

Conditions
-----------------
Vaccination, Wastewater Surveillance

Intervention / Treatment
-----------------
* Behavioral: Wastewater vaccine prompts


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: None - county-level vaccine uptake - no direct interaction with people getting vaccines Exclusion Criteria: None
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Other
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Difference-in-differences
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Intervention arm<br>Receives communications on level of SARS-CoV-2 as identified in the wastewater | Behavioral: Wastewater vaccine prompts<br>* Social media communications showing levels of SARS-CoV-2 in wastewater<br>|
| No Intervention: Comparison arm<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Vaccine uptake | Number of individuals receiving a booster COVID-19 vaccine | up to 3 months |
Troriluzole Individual Patient IND Expanded Access Program

Study Overview
=================
Brief Summary
-----------------
This is an expanded access program to provide troriuzole for treatment of spinocerebellar ataxia.

Detailed Description
-----------------
This expanded access program is designed to provide access to troriluzole for patients with spinocerebellar ataxia who are not eligible for other troriluzole clinical trials, and who in the opinion of the treating physician would potentially benefit from treatment with troriluzole. Requests by treating physicians to file a single patient investigational new drug application as part of the expanded access program for troriluzole will be considered on a case-by-case basis.

Official Title
-----------------
Expanded Access Use of Troriluzole for Spinocerebellar Ataxia

Conditions
-----------------
SCA, Spinocerebellar Ataxias

Intervention / Treatment
-----------------
* Drug: Troriluzole


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patient has confirmed diagnosis of spinocerebellar ataxia (SCA) In the opinion and clinical judgement of the Physician, potential benefit outweighs potential risk of receiving an investigational therapy, based on the individual patient's medical history and program eligibility criteria and judged by the treating physician to be medically suitable for treatment with troriluzole. Adequate hepatic function Exclusion Criteria: Patient is known to have acute or chronic liver disease that is clinically significant in the Physician's judgment Patient has a history of a clinically significant medical condition that would interfere with the patient's ability to comply with the expanded access treatment instructions or would place the patient at increased risk

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: Troriluzole|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
Auxiliary Anesthesia Technique for Extracting Advanced Hemodynamic Parameters Based on Peripheral Arterial Waveform Photography

Study Overview
=================
Brief Summary
-----------------
In this study, the arterial blood pressure waveform was digitized by snapshots or videos of the patient monitor to further estimate advanced hemodynamic parameters, so as to realize continuous and automatic monitoring of advanced hemodynamics on mobile devices to assist anesthesia, with a view to developing an Android/iOS application for mobile devices and application in patient management.

Official Title
-----------------
Auxiliary Anesthesia Technique for Extracting Advanced Hemodynamic Parameters Based on Peripheral Arterial Waveform Photography

Conditions
-----------------
Anesthesia

Intervention / Treatment
-----------------
* Procedure: snapshots or videos of monitor
* Procedure: Pressure transducer


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Invasive blood pressure monitoring Aged 18-65 years ASA class I-III Exclusion Criteria: Spontaneous breathing Prone position Non-radial artery cannulation Aortic regurgitation Heart arrhythmia Heart rate > 100/min Intra-aortic balloon pump Peripheral vascular disease Body weight < 40 kg

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| General anesthesia Patients<br>Subjects experiencing general anesthesia | Procedure: snapshots or videos of monitor<br>* The mobile device（a phone）was used to obtain the screen image of the monitor, and the arterial blood pressure waveform is extracted by image processing technology.<br>Procedure: Pressure transducer<br>* Arterial catheter were connected to conventional pressure transducers and Flotrac-Vigileo transducers.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Comparison of mobile device analysis results with Vigileo analysis results | Cardiac output and Stroke Volume Variation were acquired by mobile device and Vigileo | 1 day | 
| Comparison of arterial waveform collected directly analysis results and Vigileo analysis results | Cardiac output and Stroke Volume Variation were acquired by Vigileo and arterial waveform collected directly analysis | 1 day | 
| Comparison of arterial waveform collected directly analysis results and mobile device analysis results | Cardiac output and Stroke Volume Variation were acquired by mobile device and arterial waveform collected directly analysis | 1 day | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
arterial blood pressure, cardiac output, advanced hemodynamic, mobile Applications
Clinical Empirical Research of ARDS

Study Overview
=================
Brief Summary
-----------------
According to the ARDS Berlin definition, patients with severe concurrent invasive mechanical ventilation were selected, and clinical data and prognosis were collected. Samples such as blood and balf were collected for analysis based on changes in the condition.

Official Title
-----------------
Clinical Empirical Research of ARDS

Conditions
-----------------
Invasive Mechanical Ventilation ARDS

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients who meet the Berlin definition of ARDS and require invasive mechanical ventilation. ARDS diagnostic criteria: according to the Berlin definition, Chest radiograph shows patchy shadows in the lungs; Respiratory failure cannot be completely caused by heart failure or excessive fluid infusion ARDS onset ≤ 3 days when included in the study Patient PaO2/FiO2 ≤ 200mmHg when included in the study Exclusion Criteria: 1) Patients with intracranial hypertension, pleural fistula, pneumothorax, HIV, HBV, HCV 2) Age>85 years old or<18 years old 3) Pregnant patients 4) Severe hemodynamic instability (vasopressor increase>30% in the first 6 hours, or Norepinephrine>0.5 mg kg/min) 5) Patients unable to perform EIT ventilation and/or perfusion testing (unable to perform internal jugular vein catheterization, Hypernatremia, chest malformation, active implant device, unstable spinal injury or fracture, skin lesions opposite the EIT monitoring area) 6) Patients with abnormal esophageal anatomical structure and inability to indwelling gastric tubes 7) Disagreement for inclusion in this study

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 100 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Overall Survival |  | 28 days |
A Study to Understand the Distribution of Obesity Classes and Obesity Related Diseases in People With Obesity Across Countries in Czech Republic, Hungary and Poland

Study Overview
=================
Brief Summary
-----------------
The study is intended to understand the distribution of different obesity classes and obesity related diseases (diseases that present along with obesity) in patients with body mass index (BMI) ≥ 30 kg/m^2. Participants will be asked to give information about their health. They will continue their normal way of life and will not get any medication or additional medical test other than those prescribed to you by their doctor. Participation in the study will last for about 1 day.

Official Title
-----------------
A Multicentre, Observational Study to Understand the Distribution of Obesity Classes and Obesity Related Comorbidities (ORCs) in People With Obesity Within a Real World Population in Czech Republic, Hungary and Poland

Conditions
-----------------
Obesity

Intervention / Treatment
-----------------
* Other: No treatment given


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Signed informed consent obtained before any study-related activities (study-related activities are any procedure related to recording of data according to the protocol). Male or female, age greater than or equal to 18 years at the time of inclusion/enrolment in the study. BMI greater than or equal to 30 Kg/m^2 as measured at the inclusion in the study Exclusion Criteria: Previous participation in this study. Participation is defined as having given informed consent in this study. Mental incapacity, unwillingness or language barriers precluding adequate understanding or cooperation as judged by physician.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| People with obesity<br>Patients with obesity coming into the clinic as part of routine visit to their treating physician/general practitioner | Other: No treatment given<br>* No treatment given<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Percentage of patients with at least one obesity related comorbidity of interest for obesity classes I, II and III pooled across all countries | % patients with obesity | At the time of enrolment (Day 1) |
Validation of AI Models to Measure Physical Activity After a Stroke

Study Overview
=================
Brief Summary
-----------------
The research team are developing algorithms using artificial intelligence that use information collected by accelerometers to detect a person's position, such as whether an individual is lying, sitting, or standing, and the individual's movements, such as whether they are taking steps or standing up. Sensor location will affect the accuracy of the model and acceptability of the method. The research team are therefore developing algorithms for four different locations. The purpose of the research is for the development of the algorithms and check whether they accurately recognise different positions and movements in people whose movement is affected by a stroke, and by being in a hospital environment (e.g. using a profiling bed). The research team plan to recruit between 34 and 50 participants who are admitted hospital due to having a stroke. After providing informed consent, participants will be asked to complete a one-off assessment with a member of the research team and a ward physiotherapist. Participants will be asked to wear the four sensors, and move through a series of postures, walk for up to six minutes, and stand as many times as they feel able in one minute.

Official Title
-----------------
Validation and Testing of Artificial Intelligence Models to Measure Physical Activity in Patients Admitted to Hospital Following a Stroke

Conditions
-----------------
Stroke

Intervention / Treatment
-----------------
* Other: No intervention


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: admitted to hospital with a diagnosis of an acute stroke. Exclusion Criteria: unable to provide informed consent; receiving end-of-life care; the consultant in charge of their care disagrees with their inclusion

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: No intervention|This is not an interventional study. The study is classified as 'pre-clinical device development or performance testing'. The purpose of the study is to develop and validate the AI models using data collected from people affected by stroke in a hospital environment, to test the accuracy of the optimised models, and to ascertain patient preference for sensor location.|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Sensitivity and specificity of AI models |  | Collected during hospitalisation (up to 12 weeks) |
Prismatic Correction for Improving Near Visual Acuity in Patients With Maculopathy

Study Overview
=================
Brief Summary
-----------------
patients with maculopathy reported in low vision clinic are tested for prismatic glasses for near vision. The pre and post visual acuity was recorded.

Detailed Description
-----------------
Diagnosed patient of maculopathy who was visited in low vision clinic are divided in two groups , one is control group (prescribed simple near vision glasses) and other is interventional group(prescribed prismatic glasses). Both groups were follow up after one month to check the improvement in near visual acuity

Official Title
-----------------
Prismatic Correction for Improving Near Visual Acuity in Patients With Maculopathy

Conditions
-----------------
Visual Acuity

Intervention / Treatment
-----------------
* Other: prismatic glasses


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Diagnosed patients of maculopathy refer to low vision clinic Patients with both genders VA from LogMAR 1.0 to LogMAR 0.3 Exclusion Criteria: Maculopathy patients with other ocular disease VA worsen the LogMAR 1.0 Patients with mental illness and other physical lmitations

Ages Eligible for Study
-----------------
Minimum Age: 40 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: prism glasses<br>prisms glasses are advised with ranging of 4prism diopters to 10 prism diopters | Other: prismatic glasses<br>* prism glasses ranging from 4-10 prism diopters<br>|
| No Intervention: presbyopic glasses<br>simple presbyopia glasses according to age are advised | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prismatic Correction for Improving Near Visual Acuity in Patients with Maculopathy | A Per forma/questionnaire is used to document Near visual Acuity with the help of light house Chart to see improvement in visual acuity | 7 -8 months |
Challenges and Concerns Faced by Parents of Children With Cleft Lip and/or Palate

Study Overview
=================
Brief Summary
-----------------
Cleft lip and/or palate (CLP) are the most common oro-facial congenital anomalies. These anomalies have an impact on feeding, speech and speech development, facial aesthetics & oral health, all of which are factors that heavily impact the quality of life of CLP patients. CLP also has an effect on the families' social and psychological health. Qualitative research helps understand the perspectives of the participants by exploring the psycho-social aspects of care. Phenomenological approach is a qualitative research method that aims to borrow participants' lived experiences to better understand a specific phenomenon. Currently, there is no clear understanding of the fears, anxieties, and challenges faced by parents of CLP patients in Egypt.

Official Title
-----------------
Understanding The Challenges and Concerns Faced by Parents of Children With Cleft Lip and/or Palate: A Qualitative Study

Conditions
-----------------
Cleft Lip and Palate

Intervention / Treatment
-----------------
* Diagnostic Test: Interview- based questionnaire


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Parents of Patients with non-syndromic CLP. Exclusion Criteria: Parents of Patients presenting with dental pain.
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Egyptian parents of cleft lip and/ or palate (CLP) patients<br>Egyptian parents of CLP patients presented to the cleft lip & palate clinic at Ain Shams university. | Diagnostic Test: Interview- based questionnaire<br>* Interview-based questionnaire by the use of an interview guide to explore and understand the Challenges faced in the past and the concerns for the future experienced by parents of CLP patients.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Challenges & concerns faced by the parents of CLP patients | The tool of measurement in the present qualitative study is In-depth interviews utilizing an interview guide (questionnaire). The recorded interviews will be transcribed by one of the authors after which thematic data analysis will be conducted. Codes will be developed by two researchers individually and intercoder meetings will held to encourage intercoder reliability. | 1 year | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Cleft Lip and Palate, Challenges, Concerns