Use of E-health Based Exercise Intervention After COVID-19

Study Overview
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Brief Summary
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Reduced subjective and objective functional capacity performance are reported after COVID-19 in a large proportion of subjects. The aim of this study is to examine the feasibility and effect of using an e-health tool for guidance and tracking of exercise training in a general population of adults previously infected by COVID19.

Detailed Description
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Both hospitalized and non-hospitalized persons who have undergone extensive multi-disciplinary rehabilitation programs report significantly improved physical function after rehabilitation. Exercise training may be the key intervention to improve fitness and subjective complaints such as fatigue, low physical fitness and dyspnea after COVID-19 infection. However, traditional group-based exercise training or self-training programs at fitness centers have been shut down during pandemic, and home-based interventions are warranted. To overcome the limitations and costs of a fitness center/personal trainer-based intervention study, more knowledge on the effectiveness and efficacy of using e-Health system to recruit, train and monitor participants after illness are needed.

Official Title
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Effect E-health Based Exercise Intervention After COVID-19

Conditions
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COVID-19

Intervention / Treatment
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* Behavioral: Exercise training using an e-health tool


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Persons who have undergone COVID-19 disease People who struggle to be physically active enough as a result of corona disease People who experience reduced physical fitness as a result of corona disease Exclusion Criteria: -- more than 100 PAI per week (calculated from self-reported activity level) uncontrolled hypertension (high blood pressure) (over 200/110). symptomatic valve failure, hypertrophic cardiomyopathy, unstable angina, pulmonary hypertension, heart failure and/or severe rhythm disturbances cancer that makes participation impossible or exercise contraindicated. Considered individually in consultation with the attending physician. chronic contagious infectious diseases. Participates in other studies that are not compatible with participation in this project Post-exertional symptom exacerbation (PESE)/post-exertional malaise (PEM)/post-exertional neuroimmune exhaustion (PENE).

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 59 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Supervised exercise<br> | Behavioral: Exercise training using an e-health tool<br>* Experimental: Exercise training will be guided by suing the e-health tool MIA with the possibility for communication and messages between the participant and study personnel The participants will wearables that record heart rate. Participants will be encourage to achieve at least 100 Personal Activity Intelligence (PAI) equivalents per week Control: No follow-up<br>|
| No Intervention: Control group<br> | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Estimated cardiorespiratory fitness | Estimated peak oxygen uptake | After 6 months intervention | 
| Feasibilty | Measured as acceptability and adherence | After 6 months intervention | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Lung function | Spirometry | After 6 months intervention | 
| Sleep quality | objective measures of sleep quality | After 6 months intervention | 
| Quality of life | Questionaires (SF-12) | After 6 months intervention |