A Smartphone Application (ACT on Vaping) for Vaping Cessation in Young Adults

Study Overview
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Brief Summary
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Almost one in ten young adults report current e-cigarette use, putting them at risk of developing nicotine addiction and long-term health effects of exposure to inhaled toxicants. Despite the need for effective treatments to help these young users quit, very few treatments targeting any type of tobacco use among young adults have been evaluated, particularly for young adults who vape and have unique treatment needs. To address these needs, this trial will evaluate a digital program for young adult e-cigarette users at all stages of readiness to quit called ACT on Vaping.

Detailed Description
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OUTLINE: Participants are randomized to 1 of 2 arms. ARM I: Participants use the ACT on Vaping smartphone app and text messaging program and receive incentivized text messages assessing their vaping status. ARM II: Participants receive incentivized text messages check-ins assessing their vaping status.

Official Title
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ACT on Vaping: Digital Therapeutic for Young Adult Vaping Cessation

Conditions
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Nicotine Dependence, Nicotine Addiction, Nicotine Use Disorder, Nicotine Vaping, Vaping

Intervention / Treatment
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* Behavioral: Smartphone app
* Other: Text Message
* Other: Survey Administration


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 18-30. Current weekly user of e-cigarette product(s). Owns an Android phone or iPhone. Has an email address. United States (US) resident, with a US mailing address. Willing to complete all study procedures. Exclusion Criteria: Currently using other tobacco cessation treatments at the time of screening, including pharmacotherapy or behavioral support (note: use of these treatments is allowable during trial participation). Member of the same household as another research participant.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 30 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Arm I (Act on Vaping app)<br>Participants receive supportive messages and use the ACT on Vaping smartphone app. They also receive incentivized text message check-ins assessing their vaping status. | Behavioral: Smartphone app<br>* Use ACT on Vaping smartphone app<br>* Other names: ACT on Vaping;Other: Text Message<br>* Receive text messages<br>* Other names: SMS Text;Other: Survey Administration<br>* Ancillary studies<br>|
| Active Comparator: Arm II (Incentivized text message check-ins)<br>Participants receive incentivized text messages check-ins assessing their vaping status. | Other: Text Message<br>* Receive text messages<br>* Other names: SMS Text;Other: Survey Administration<br>* Ancillary studies<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Overall treatment satisfaction rating | Will calculate descriptive statistics (e.g., means, proportions) for the ACT on Vaping treatment group to assess treatment satisfaction (i.e., mean level of overall satisfaction with ACT on Vaping, with 3.5 on a 5-point scale being the go criterion). | At 3 months | 
| Change in readiness to quit | Will evaluate differences of Contemplation Ladder scores. | From baseline to 3 months post-randomization | 
| Self-reported 24-hour quit attempt | Will evaluate differences descriptively. | At 3 months post-randomization | 
| Cotinine-confirmed 30-day point prevalence abstinence from all nicotine and tobacco | Will evaluate differences descriptively. | At 3 months post-randomization |