Prediction of the Risks of Cardiovascular Mortality

Study Overview
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Brief Summary
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Monitoring risks of cardiovascular diseases in working population (18 - 65 years old) by monitoring their BMI, ankle-brachial index with pulse wave velocity, cholesterol and glycemia.

Detailed Description
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Monitoring working population in their workplace by measuring their ankle-brachial index with pulse wave velocity, BMI, glycemia and cholesterol. Putting acquired data in correlation to their work habits, type of employment, work demands, job type, activity levels. Trying to find common predictors of cardiovascular disease. All assessed subjects must understand written and spoken Czech, must be employed in a company that consents with our data collections, must be older than 18 year old, doesn't have any bleeding disorder, doesn't have deep vein thrombosis (as it produces inaccurate data with ankle brachial index). Study will be conducted in Ustecky Region in the Czech Republic on approximately 200 subjects.

Official Title
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Prediction of the Risks of Cardiovascular Mortality

Conditions
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Embolism, Cardiovascular Diseases, Cardiovascular Morbidity, Stroke, Cardiac Arrest

Intervention / Treatment
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* Device: Ankle-brachial index - system 100


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: employed in Ustecky Region Czech Republic adult understands spoken and written Czech consents with assessment works in a company that consents to assessments of their employees Exclusion Criteria: deep vein thrombosis not currently employed on sick leave bleeding disorder

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Device: Ankle-brachial index - system 100|Measurement of ankle brachial index on all four limbs, drawing three blood drops for point of care (POC) cholesterol meter and one drop of blood for POC glucometer|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Detection of glycemia, HDL, LDL and triacylglyceride levels | Glycemia, HDL, LDL and triacylglyceride levels (mmol/l) will be measured from drops of blood by point-of-care analysers | 5 minutes | 
| Body composition | Using body composition scale the following markers will be counted: bone mass, body fat, muscle mass, water levels. All results will be in % | 3 minutes | 
| Ankle-brachial index | Ankle-brachial index (no unit) using ABI-system-100 will be counted from blood pressure measured in all four limbs (mmHg) | 2 minutes | 
| Ankle brachial pulse wave velocity (baPWV) and carotid femoral pulse wave velocity (cfPWV) | baPWV and cfPWV will be measure by ABI-system-100 (m/s) | 2 minutes | 
| Weight | measured by body composition scale (kg) | 1 minute | 
| Height | measured by tailor tape measure (m) | 1 minute | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| BMI | BMI (kg/m^2) will be counted from weight (kg) and height (m) | 2 minutes | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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ankle-brachial index, cardiovascular mortality, prevention