Magnesium Citrate Supplementation on Hand Grip Strength

Study Overview
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Brief Summary
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The purpose of this research study is to determine the effectiveness of magnesium on handgrip strength using the more bioavailable magnesium citrate.

Detailed Description
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In this single-blind, randomized trial, participants will take a daily dose of either 200 or 400 milligrams of magnesium citrate supplement for four weeks, perform three separate handgrip strength tests using a dynamometer, complete a demographics questionnaire, a physical activity questionnaire, and a compliance log.

Official Title
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The Effects of Magnesium Citrate Supplementation on Hand Grip Strength: A Randomized Control Trial

Conditions
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Hand Grasp

Intervention / Treatment
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* Dietary Supplement: Magnesium


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Generally healthy community adults Individuals age 18 and over Male and female participants Exclusion Criteria: Individuals currently on magnesium supplements Individuals currently on a multivitamin supplement Individuals who currently suffer from hand pain or hand injury Individuals who currently suffer from arthritis in their hands Individuals suffering from a gastrointestinal disorder complicated by diarrhea, nausea, or abdominal cramping

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Group 1: participants take 200 mg of magnesium citrate daily for 4 weeks. Group 2: participants take 400 mg of magnesium citrate daily for 4 weeks.
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: 200 mg Magnesium<br>Participant will take 200 mg of magnesium citrate daily for 4 weeks | Dietary Supplement: Magnesium<br>* Magnesium citrate of either 200mg or 400 mg will be taken by the participant with food in the morning.<br>|
| Active Comparator: 400 mg Magnesium<br>Participant will take 400 mg of magnesium citrate daily for 4 weeks | Dietary Supplement: Magnesium<br>* Magnesium citrate of either 200mg or 400 mg will be taken by the participant with food in the morning.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Hand grip strength | Participants will perform three separate handgrip strength tests using a Jamar Plus digital hand dynamometer, (Sammons Preston, Bolingbrook, Illinois). In each test, participants will do three trials resting for 15 seconds between trials, the average of the three trials will be recorded. To perform the hand grip strength test, the participant will hold the dynamometer in their dominant hand, with the arm at a right angle, and with the elbow by the side of the body. The participant then squeezes the hand dynamometer with maximum isometric effort for at least five seconds. Participants are required to not move any other part of the body and are encouraged to use maximum effort. | change between baseline and 4 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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hand grip magnesium citrate