Evaluation of Cardiovascular Risk After Preeclampsia in General Practitioners and Patients

Study Overview
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Brief Summary
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Pre-eclampsia is a disease characterized by placental damage leading to a cascade of complications during pregnancy. It is initially manifested by high blood pressure and the presence of albumin in the urine. It can lead to emergency hospitalization in severe cases and cause major complications or even death in the mother and the fetus. Several studies observing the outcome of patients with pre-eclampsia have shown an increased long-term cardiovascular risk in these patients, justifying regular medical follow-up with the treating physician and specialists, mainly cardiologists. The main objective of this research is to describe the cardiovascular risk assessment actions implemented by the treating general practitioner in the year following pre-eclampsia (blood pressure measurement in the office, self-measurement of blood pressure, ABPM, cardiological consultation, biological monitoring of blood (creatininemia, LDL, fasting glycemia) or urine (albuminurie/creatininurie ratio), and screening and management of possible smoking).

Official Title
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Evaluation of Cardiovascular Risk After Preeclampsia in General Practitioners and Patients

Conditions
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Patients Hospitalized for Pre-eclampsia

Intervention / Treatment
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* Other: Patient with pre-eclampsia


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients ≥ 18 years hospitalized for preeclampsia at the Nancy regional maternity hospital Exclusion Criteria: Fetal death in utero; Adult Person subject to a legal protection measure (guardianship, curatorship, safeguard of justice); Person deprived of liberty by a judicial or administrative decision; Person subject to psychiatric care under constraint by virtue of articles L. 3212-1 and L. 3213-1 of the Public Health Code.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Patient with pre-eclampsia|Cardiovascular risk assessment by the general practitioner in the year following pre-eclampsia|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Performing a blood pressure measurement by the general practitioner | Description: Describe the cardiovascular risk assessment actions implemented by the general practitioner in the year following pre-eclampsia within the following specific monitoring tools such as blood pressure measurement in the office. Composite outcome with 2, 3, 4, 5 and 6 | Up to one year following pre eclampsia | 
| Performing a self-measurement of blood pressure | Description: Describe the cardiovascular risk assessment actions implemented by the general practitioner in the year following pre-eclampsia within the following specific monitoring tools such as self-measurement of blood pressure. Composite outcome with 2, 3, 4, 5 and 6 | Up to one year following pre eclampsia | 
| Performing a cardiological consultation | Description: Describe the cardiovascular risk assessment actions implemented by the general practitioner in the year following pre-eclampsia within the following specific monitoring tools such as cardiological consultation. Composite outcome with 2, 3, 4, 5 and 6 | Up to one year following pre eclampsia | 
| Performing a ambulatory measurement of blood pressure | Description: Describe the cardiovascular risk assessment actions implemented by the general practitioner in the year following pre-eclampsia within the following specific monitoring tools such as ambulatory measurement of blood pressure. Composite outcome with 2, 3, 4, 5 and 6 | Up to one year following pre eclampsia | 
| Performing a biological monitoring of blood (creatinine, LDL cholesterol, fasting glucose, albuminuria creatinuria ratio) | Description: Describe the cardiovascular risk assessment actions implemented by the general practitioner in the year following pre-eclampsia within the following specific monitoring tools such as biological monitoring of blood (creatinine, LDL, fasting glucose) or urine (Albuminuria/creatininuria ratio). Composite outcome with 2, 3, 4, 5 and 6. | Up to one year following pre eclampsia | 
| Screening and management of possible smoking | Description: Describe the cardiovascular risk assessment actions implemented by the general practitioner in the year following pre-eclampsia within the following specific monitoring tools such as screening and management of possible smoking. Composite outcome with 1, 2, 3, 4 and 5 | Up to one year following pre eclampsia | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cardiovascular risk assessment by the general practitioner | Patient's cardiovascular risk evaluation by the general practitioner (low, medium, high or very high). | Up to 5 years following pre eclampsia | 
| Cardiovascular risk assessment by the patient | Patient's cardiovascular risk evaluation by the patient (low, medium, high or very high). | Up to 5 years following pre eclampsia | 
| Knowledge of pre-eclampsia status | Knowledge of the pre-eclampsia status of the patient by the general practitioner. | Up to 5 years following pre eclampsia | 
| Pre eclampsia information mode | How general practitioner is informed about pre-eclampsia | Up to 5 years following pre eclampsia | 
| Performing a blood pressure measurement | Actions implemented by the general practiotioner within the following specific tools as reported by the patient such as blood pressure measurement in the office. | Up to one year following pre eclampsia | 
| Performing a self-measurement of blood pressure | Actions implemented by the general practiotioner within the following specific tools as reported by the patient.such as self-measurement of blood pressure. | Up to one year following pre eclampsia | 
| Performing a cardiological consultation | Actions implemented by the general practiotioner within the following specific tools as reported by the patient such as cardiological consultation. | Up to one year following pre eclampsia | 
| Performing a ambulatory measurement of blood pressure | Actions implemented by the general practiotioner within the following specific tools as reported by the patient such as ambulatory measurement of blood pressure. | Up to one year following pre eclampsia | 
| Performing a biological monitoring of blood (creatinine, LDL cholesterol, fasting glucose, albuminuria creatinuria ratio) | Actions implemented by the general practiotioner within the following specific tools as reported by the patient such as biological monitoring of blood (creatinine, LDL, fasting glucose) or urine (Albuminuria/creatininuria ratio). | Up to one year following pre eclampsia | 
| Screening and management of possible smoking | Actions implemented by the general practiotioner within the following specific tools as reported by the patient such as screening and management of possible smoking. | Up to one year following pre eclampsia | 
| Rate of hypertension following pre-eclampsia | Composite endpoint of hypertension, stroke and/or coronary accident with 17;18 | Up to 5 years following pre eclampsia | 
| Rate of stroke following pre-eclampsia | Composite endpoint of hypertension, stroke and/or coronary accident with 16;18 | Up to 5 years following pre eclampsia | 
| Rate of coronary accident following pre-eclampsia | Composite endpoint of hypertension, stroke and/or coronary accident with 16;17 | Up to 5 years following pre eclampsia | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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pre-eclampsia, cardiovascular risk