McGrath Videolaryngoscopy and Direct Laryngoscopy Rapid Sequence Intubation

Study Overview
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Brief Summary
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The study seeks to compare the efficacy of conventional direct laryngoscopy using a Macintosh blade with the McGrath videolaryngoscope for rapid sequence endotracheal intubation.

Detailed Description
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The study aims to conduct a multicenter international trial to enroll a maximum of 800 consenting adults who fall under the American Society of Anesthesiologists (ASA) physical status 1-3 category and require elective non-cardiac surgery necessitating endotracheal intubation with rapid sequence induction for general anesthesia. The study seeks to compare the efficacy of conventional direct laryngoscopy using a Macintosh blade with the McGrath videolaryngoscope for rapid sequence endotracheal intubation.

Official Title
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Comparison of Comparison of McGrath Videolaryngoscopy and Direct Laryngoscopy for Rapid Sequence Intubation: an International, Multicenter Randomized Trial

Conditions
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Surgery

Intervention / Treatment
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* Other: Conventional direct laryngoscopy using a Macintosh blade
* Device: McGrath videolaryngoscope for rapid sequence endotracheal intubation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Elective surgery requiring oral endotracheal intubation for general anesthesia; Anticipated extubation in the operating room; American Society of Anesthesiologists (ASA) physical status 2-3; Age between 18 and 99 years; Body Mass index ≥ 40 kg/m2. Exclusion Criteria: Refusal of participation by attending anesthesiologist; Indicated rapid sequence induction for any reason including, but not limited to high risk of aspiration Indicated fiberoptic awake intubation.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 99 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Efficacy of conventional direct laryngoscopy<br>The researchers seeks to compare the efficacy of conventional direct laryngoscopy using a Macintosh blade, | Other: Conventional direct laryngoscopy using a Macintosh blade<br>* Examine a patient's airway to aid placement of tracheal tube with ease.<br>|
| Experimental: McGrath Videolaryngoscope for rapid endotracheal intubation<br>The researchers will use the McGrath videolaryngoscope for rapid sequence endotracheal intubation. | Device: McGrath videolaryngoscope for rapid sequence endotracheal intubation<br>* Visualize a patient's airway to aid placement of tracheal tube with ease.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visualization of the vocal cords | Our primary outcomes is visualization of the vocal cords, defined using the modified Cormack and Lehane classification | Within 1 hours anesthesia induction. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of intubation attempts, and failures. | Secondary outcomes are number of intubation attempts and the number of intubation failures. | Within 1 hour of anesthesia induction. |