Comparison of Two Different Pupillometer

Study Overview
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Brief Summary
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Pupil diameter is parameter of great interest in understanding brain systems and modern refractive surgery. Pupillometry, the measurement of variations in pupil dilation, has offered encouraging evidence for the involvement of disturbed reactivity in depression risk, according to studies. Traditional vision screening methods in children can be difficult due to poor cooperation and labour-intensive procedure, and therefore, a handheld photorefractometer offers reduced assessment time in detecting refractive errors. 2WIN uses infrared light, the patient is not aware of the several, rotating photoscreen images being exposed to afford multiaxial estimation of spherical and astigmatic refractive error.The purpose of this prospective study was to compare 2WIN and OPD Scan III pupillometers.

Detailed Description
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Pupil diameter is a parameter of great interest in understanding brain systems and modern refractive surgery. Pupillometry, the measurement of variations in pupil dilation, has offered encouraging evidence for the involvement of disturbed reactivity in depression risk, according to studies. According to research, the pupil dilates in reaction to stimuli requiring a larger cognitive load or a greater emotional intensity. Importantly, studies have related pupil size variations to brain activity in regions associated with emotion regulation, including the dorsolateral prefrontal cortex (DPFC) and the agenesis of the corpus callosum (ACC) . Thus, pupillometry is proposed as a viable peripheral gauge for a variety of brain systems involved in the processing of emotional information. Some of the postoperative complaints of patients having refractive corneal or lens surgery are related to visual quality and are associated with large pupils since optical aberrations become more dominant when the pupil dilates . If the pupil size exceeds the optical zone size, a marked increase in higher-order aberrations could be observed. Patients might complain about poor contrast sensitivity, increased glare disability, or halos. Precise measurement of pupil diameter has therefore become an essential step in the preoperative evaluation of patients suitable for refractive surgery and is an important inclusion or exclusion criterion. The purpose of this study is to assess the consistency of pupil diameter measurements between the two machines.

Official Title
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Comparison of Two Pupillometer for Determining Pupil Diameter in Healthy Participants

Conditions
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Measurement of Pupil Diameter

Intervention / Treatment
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* Device: 2WIN
* Device: OPD


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: >18 years old signed informed consent willing to participate in the study Exclusion Criteria: abnormalities of the pupil (e.g., synechia, ectopia) corneal scars irregular astigmatism strabismus acute or chronic uveitis any kind of previous eye surgery medication that could have an influence on pupil reaction or size

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Device: 2WIN|Determining pupil diameter by 2WIN|
|Device: OPD|Determining pupil diameter by OPD|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pupil size | Photopic and mesopic pupil size will be measured using 2WIN photoscreening with OPD Scan III. | 1 day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Refractive Accuracy | Refractive measurements using 2WIN photoscreening with Nidek ARK-1 Autorefractor. | 1 day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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2WIN, pupil diameter