Hemophilic Knee Arthropathy Virtual Reality

Study Overview
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Brief Summary
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This study intended to examine the effect of a physical rehabilitation program incorporating Kinect-based virtual reality on gait characteristics, functional ability, and physical activity level in adolescents with hemophilic knee arthropathy.

Detailed Description
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The usage of virtual reality in clinical practice as an alternative for conventional procedures has recently sparked the interest of health professionals. Virtual reality is a type of computer technology that provides simulated sensory feedback to allow children to participate in activities and events that are comparable to those they could face in real life. It can be used therapeutically to enhance strength, range of motion, coordination, mental concentration, problem solving, decision making, balance, and gait.

Official Title
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Adolescents With Hemophilic Knee Arthropathy Can Improve Their Gait Characteristics, Functional Ability, and Physical Activity Level Through Kinect-based Virtual Reality: a Randomized Clinical Trial

Conditions
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Hemophilia, Knee Arthropathy

Intervention / Treatment
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* Other: virtual reality group
* Other: exercise group


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: moderate hemophilia bilateral involvement of the knee joint medically stable and received their factor replacement therapy free from contracture or congenital anomalies didn't have persisting, disabling pain. Exclusion Criteria: recent bleeding episodes severe radiological abnormalities such as bone erosions, degeneration, bone ankylosis, or joint subluxation engagement in a regular exercise program in the past six months the unwillingness to stick to the training schedule

Ages Eligible for Study
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Minimum Age: 10 Years
Maximum Age: 14 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: study group<br>a 30-minute VR-based training session utilizing Kinect Xbox after the session of traditional physical therapy. | Other: virtual reality group<br>* a 30-minute VR-based training session utilizing Kinect Xbox after the session of traditional physical therapy.<br>* Other names: Kinect based virtual reality combined with physical exercises;Other: exercise group<br>* Traditional physical therapy, 30-minutes physical therapy exercise program each week with 48-hour intervals at least<br>* Other names: physical exercises alone;|
| Experimental: control group<br>Traditional physical therapy, 30-minutes physical therapy exercise program each week with 48-hour intervals at least | Other: exercise group<br>* Traditional physical therapy, 30-minutes physical therapy exercise program each week with 48-hour intervals at least<br>* Other names: physical exercises alone;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Gait Analysis | Each participant was instructed to walk bare feet with a comfortable, self-selected speed along a 10-meter walkway while the trajectories of reflective markers and forces were respectively recorded through 12 optoelectronic cameras (Vicon Motion Systems Ltd., Oxford, UK) with a 120-Hz sampling rate and two force plates at 1000 Hz. | at first week | 
| Gait Analysis | Each participant was instructed to walk bare feet with a comfortable, self-selected speed along a 10-meter walkway while the trajectories of reflective markers and forces were respectively recorded through 12 optoelectronic cameras (Vicon Motion Systems Ltd., Oxford, UK) with a 120-Hz sampling rate and two force plates at 1000 Hz. | after 12 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Functional ability assessment | The 6-minute walk test was used to assess functional abilities. | at first week | 
| Functional ability assessment | The 6-minute walk test was used to assess functional abilities. | after 12 weeks | 
| Physical activity level assessment | The Adolescents' Physical Activity Questionnaire (PAQ-A) in Arabic edition was used to measure the physical activity level assessment. | at first week | 
| Physical activity level assessment | The Adolescents' Physical Activity Questionnaire (PAQ-A) in Arabic edition was used to measure the physical activity level assessment. | after 12 weeks |