The Impact of App-based Cognitive Training on Post-stroke Upper Extremity Rehabilitation

Study Overview
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Brief Summary
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To find out the impact of app-based cognitive training on upper extremity function in patients with sub-acute stroke.

Official Title
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The Impact of App-based Cognitive Training on Post-stroke Upper Extremity Rehabilitation

Conditions
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Stroke

Intervention / Treatment
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* Other: traditional physical therapy
* Other: mobile app-based cognitive training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients aged 45-70 years. Both male and female gender. Patients of sub-acute stroke patients with impaired upper extremity function Stroke patients suffering from mild to moderate cognitive impairment. Patients with the ability to fulfill and comprehend commands Exclusion Criteria: Patients of neurodegenerative diseases like Parkinson's, multiple sclerosis etc. Patients suffering from any severe psychological disorder. Patients with severe contracture due to orthopedic disease of the shoulder, elbow, and wrist joints

Ages Eligible for Study
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Minimum Age: 45 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Traditional physical therapy<br>This group will receive conventional upper extremity rehabilitation including active and active assisted ROMs and upper extremity stretches for 30 minutes, three to five times a week for 6 weeks. | Other: traditional physical therapy<br>* this group received conventional upper extremity active ROMs and stretches for 30 minutes three to five times a week for 6 weeks without using the app-based cognitive training.<br>|
| Experimental: The impact of app-based cognitive training<br>The experimental group received mobile-app-based cognitive training (PEAK) along with conventional upper extremity rehabilitation. | Other: mobile app-based cognitive training<br>* This group received mobile app-based cognitive training of 30minutes session three to five times a week for 6 weeks which includes a few activities such as the memory, coordination and alertness along with conventional UE exercises for 15 minutes three to five times a week for 6 weeks.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| upper extremity function | Fugl-Meyer Assessment-Upper Extremity (FMA-UE) The FMA-UE is a condition-specific outcome that applies to hemiparesis of the upper limb in stroke conditions. The FMA motor assessments for the upper (maximum score 66 points) | 4th week | 
| Trail Making Test | The Trail Making Test is a neuropsychological test of visual attention and task switching. It has two parts, in which the subject is instructed to connect a set of 25 dots as quickly as possible while maintaining accuracy. Scoring is based on time taken to complete the test (e.g. 35 seconds yielding a score of 35) with lower scores being better. Different norms are available that allow comparison with age-matched groups | 4th week | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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stroke, sub-acute stroke, cognitive impairment