linjc16/ctgov huggingface dataset:
Pulmonaryhypertension in Copd at Different Levels of Smoking

Study Overview
=================
Brief Summary
-----------------
To identify Predictors of pulmonary hypertension in COPD patients and its relation to different levels of smoking

Detailed Description
-----------------
COPD is a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea, cough, expectoration and/or exacerbations) due to abnormalities of the airways (bronchitis, bronchiolitis) and/or alveoli (emphysema) that cause persistent, often progressive, airflow obstruction.It is also the most common cause of deaths in patients with chronic respiratory disease, the fatality rate in USA is 0.41%.Pulmonary Hypertension is the most common serious complication in COPD patients ; which occurs in up to 30% of patients and increases the mortality rate.Smoking is the leading cause of chronic obstructive pulmonary disease (COPD) Smoking is also a trigger for COPD flare-ups.Smoking damages the air sacs, airways, and the lining of your lungs. Injured lungs have trouble moving enough air in and out, so it's hard to breathe

Official Title
-----------------
Clinical Characteristics and Predictors of Pulmonary Hypertension in COPD at Different Levels of Smoking

Conditions
-----------------
Pulmonary Hypertension

Intervention / Treatment
-----------------
* Diagnostic Test: Echocardiography and HRCT


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 1.All patients admitted to chest department or presented to our outpatient clinic with clinical and functional diagnosis of COPD among both sexes will be included 2.Age >18 years Old Exclusion Criteria: 1.Patients under 18 years old. 2.pregnant patients. 3.patients with history hypertension or valvular diseases 4.Cardiomyopathic patient 5.Patients with concomitant obstructive sleep apnea 6.Patients with collagen vascular disease 7.Patients with thrombo-embolic disease 8. Patients with any chronic chest disease other than COPD

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 100 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: Echocardiography and HRCT|Echocardiography:is non invasive and easily accessible tool in the diagnosis of any patient with suspected PH.HRCT: is a non-invasive and easily accessible tool to detect pulmonary hypertension in COPD patients.|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Predictors of pulmonary hypertension in COPD patients | Predict pulmonary hypertension in COPD patients | 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Relationship between different levels of smoking and predictors of degree of pulmonary hypertension | Levels of smoking (mild.moderate.sever.non smoker) and it's relation to pulmonary hypertension in COPD patients | 1 year |
3D Printed Personalized Extendable Prosthesis

Study Overview
=================
Brief Summary
-----------------
The goal of this type of observational study is to investigate the preliminary effect of 3D printed personalized extendable prosthesis replacement on limb salvage in children with osteosarcoma. The main question it aims to answer is: Is 3D printed personalized extendable prosthesis replacement has a good outcome in limb salvage pediatric osteosarcoma？

Detailed Description
-----------------
Osteosarcoma is one of the most common primary malignant bone tumors in children and adolescents. In this study, the investigators try to investigate the preliminary effect of 3D printed personalized extendable prosthesis replacement on limb salvage in children with osteosarcoma.

Official Title
-----------------
3D Printed Personalized Extendable Prosthesis Replacement for Limb Preservation in Children With Osteosarcoma: a Preliminary Study

Conditions
-----------------
Osteosarcoma in Children

Intervention / Treatment
-----------------
* Device: 3D printed personalized extendable prosthesis


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: tumors of the extremities, with moderate soft-tissue invasion the neurovascular bundle is not invaded, and the tumor can be excised totally no metastatic lesions or metastases can be cured Exclusion Criteria: recurrent tumors poorly differentiated tumors poor soft-tissue conditions neurovascular invasion around tumors ineffective chemotherapy with metastasis

Ages Eligible for Study
-----------------
Minimum Age: 6 Years
Maximum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| 3D printed<br>3D printed personalized extendable prosthesis replacement for limb preservation in children with osteosarcoma | Device: 3D printed personalized extendable prosthesis<br>* 3D printed personalized extendable prosthesis replacement for limb preservation in children<br>|
| amputation<br>patients had undergone amputation of the limbs | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Recurrence | Osteosarcoma recurrence rate | 7years |
Investigating Clinical Trial Participation for Acne Patients

Study Overview
=================
Brief Summary
-----------------
Participation in medical trials usually favors a particular demographic group. But there is limited research available to explain what trial attributes affect the completion of these specific demographic groups. This trial will scrutinize the experiences of patients diagnosed with acne as they take part in a separate medical intervention clinical trial. The focus will be on tracking the rates of completion and withdrawal among these individuals. It will also try to analyze data from the perspective of different demographic groups to check for recurring trends which might yield insights for the sake of future acne patients.

Official Title
-----------------
An Assessment of Clinical Trial Experiences of Patients With Acne

Conditions
-----------------
Acne

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patient has been diagnosed with acne Patient is able to read, understand and provide written Informed Consent Patient is a minimum of 18 years or older Exclusion Criteria: Inability to perform regular electronic reporting Pregnant or lactating women Has significant intercurrent illness, psychiatric disposition or other factors that, in the opinion of the Investigator or Medical Monitor, precludes participation in the study

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of acne patients who decide to join in a clinical study |  | 3 months | 
| Rate of patients who remain in an acne clinical study to completion |  | 12 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
acne
Application of Artificial Intelligence on the Diagnosis of Helicobacter Pylori Infection and Premalignant Gastric Lesion

Study Overview
=================
Brief Summary
-----------------
The aim of this diagnostic accuracy study is to evaluate the application of artificial intelligence on the diagnosis of Helicobacter pylori infection and premalignant gastric lesions based on upper endoscopic images. We use techniques of artificial intelligence to analyze the correlation between endoscopic images and urea breath test results/histopathological results.

Detailed Description
-----------------
This study had invited patients to undergo urea breath test, upper gastrointestinal endoscopy, and histology examination. The study will collect their tests results, upper gastrointestinal endoscopy images, and histopathological results. Artificial intelligence techniques will be used to analyze the correlation between endoscopic images and urea breath test results/histopathological results. We aim to establish a telemedicine system to assist clinicians in diagnosing Helicobacter pylori infection and detecting premalignant gastric lesion using upper endoscopic images. The system will be implemented as a telemedicine service system in the rural areas, for example Matsu Islands. The baseline histological predictions will be linked to the newly incident gastric cancer.

Official Title
-----------------
Application of Artificial Intelligence on the Diagnosis of Helicobacter Pylori Infection and Premalignant Gastric Lesion: A Multihospital Study

Conditions
-----------------
Helicobacter Pylori Infection, Premalignant Lesion

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age 20-80 Scheduled urea breath test and endoscopy Exclusion Criteria: 1. History of gastric surgery

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Helicobacter pylori infection and premalignant gastric lesion<br>Application of artificial intelligence to analyze the correlation between endoscopic images and urea breath test results/histopathological results. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Sensitivity to detect premalignant gastric lesions | Outcomes include the atrophic gastritis, intestinal metaplasia, and Helicobacter pylori infection | Up to 5 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Specificity to exclude premalignant gastric conditions | Outcomes include the atrophic gastritis, intestinal metaplasia, and Helicobacter pylori infection | Up to 5 years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Helicobacter, Artificial Intelligence, Telemedicine
An Observational Study of Patients With Chronic Gastrointestinal Disease

Study Overview
=================
Brief Summary
-----------------
TARGET-GASTRO is an observational research study to conduct a comprehensive review of outcomes for patients with the chronic gastrointestinal (GI) diseases: eosinophilic gastrointestinal disease (EGID), ulcerative colitis (UC) or Crohn's disease (CD).

Official Title
-----------------
An Observational Study of Patients With Chronic Gastrointestinal Disease

Conditions
-----------------
Gastrointestinal Diseases

Intervention / Treatment
-----------------
* Other: Observational


Participation Criteria
=================
Eligibility Criteria
-----------------
Disease Cohort Inclusion Criteria: Adult* patients at the time of enrollment with a diagnosis or major symptom of EGIDs, UC, or CD by ICD-10 code in the EHR interface Exclusion Criteria: Death Manual removal (sponsor or site request) No EHR interface encounter > 3 years. Engaged Cohort Inclusion Criteria: Adult* patients diagnosed and managed for these conditions invited to participate Ability to provide written informed consent Exclusion Criteria: Patient expressed desire to withdraw consent to complete PROs Failure to complete PROs within 24 weeks of initial invitation Greater than 24 months lapse of survey completion after baseline surveys completed Additionally, the criteria detailed for Disease Cohort apply to the Engaged Cohort.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Disease Cohort<br>Observational | Other: Observational<br>* Observational<br>|
| Engaged Cohort<br>Observational | Other: Observational<br>* Observational<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To characterize the natural history of disease in patients with GI disease from various etiologies |  | 20 Years | 
| To assess safety and effectiveness of treatments |  | 20 Years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To evaluate provider management practices in the treatment of patients with EGIDs, UC and CD |  | 20 Years | 
| To evaluate longitudinal and patient reported outcomes in patients with EGIDs, UC and CD |  | 20 Years | 
| To select and evaluate quality of care measures for patients with GI Diseases |  | 20 Years |
National Survey of Young Adult Nutrition

Study Overview
=================
Brief Summary
-----------------
The purpose of this research is to better understand how people's background, habits, and other factors influence their diets and health.

Detailed Description
-----------------
The purpose of this study is to provide further insight into the correlates and predictors of young adults' eating habits, with particular emphasis on sociodemographics, reproductive health, and food upbringing.

Official Title
-----------------
National Survey of Young Adult Nutrition

Conditions
-----------------
Overweight or Obesity

Intervention / Treatment
-----------------
* Other: Study participants


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: U.S. citizens Current, full-time, non-institutionalized residents of the United States Access to a computer with internet access Exclusion Criteria: Non-U.S. citizens Non-resident of the United States No access to a computer with internet access

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 24 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Study participants<br>Participants will complete survey and dietary assessment. | Other: Study participants<br>* Participants will complete study survey and dietary assessment.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Diet quality | Diet quality as estimated using the Healthy Eating Index-2015, based on reported dietary intake. | Baseline | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Healthy Weight
Multiparameter Ultrasound Based-AI for the Diagnosis of Thyroid Nodules

Study Overview
=================
Brief Summary
-----------------
The cases that fulfill the inclusion criteria will be enrolled with written informed consent. Images and videos will be collected in accordance with the procedure, uploaded to Ruiying Cloud, followed up, and registered with basic case information, such as thyroid function, FNA/surgical pathology results, etc.

Official Title
-----------------
Multiparameter Ultrasound Based-AI for the Diagnosis of Thyroid Nodules: an International Multi-center Study

Conditions
-----------------
Thyroid Nodule

Intervention / Treatment
-----------------
* Diagnostic Test: Multiparameter ultrasound based-AI


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 18 80 years old; Thyroid nodules (ACR-TI RADS category 3-5，category 3 nodules ≥1cm submitted for FNA) or clustered micro-calcifications; The patients schedule to perform FNA/surgery within 1 month; Without any history of invasive procedure of thyroid before (such as FNA,CNB, ablation, radiation, or surgery). Exclusion Criteria: Incomplete data; Contraindications of CEUS

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: Multiparameter ultrasound based-AI|Multiparameter ultrasound based-AI for the diagnosis of thyroid nodules|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of Participants with 1827 Nodule Classification | nodules with Pathology or cytopathology result | up to 4 weeks |
The Effects of Luo-Bu-Fu-Ke-Bi-RI Pill

Study Overview
=================
Brief Summary
-----------------
To investigate the effect of LBFKBRP on climacteric syndrome in women and explore its therapeutic mechanism.

Official Title
-----------------
The Effects of Luo-Bu-Fu-Ke-Bi-RI Pill

Conditions
-----------------
Climacteric Syndrome

Intervention / Treatment
-----------------
* Drug: Luo-Bu-Fu-Ke-Bi-RI Pill
* Drug: tibolone


Participation Criteria
=================
Eligibility Criteria
-----------------
Clinical diagnosis of climacteric syndrome

Ages Eligible for Study
-----------------
Minimum Age: 41 Years
Maximum Age: 60 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| control group<br> | Drug: tibolone<br>* 2.5 mg once daily<br>|
| treatment group<br> | Drug: Luo-Bu-Fu-Ke-Bi-RI Pill<br>* 10 pills twice daily<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Sex hormone |  | 3 month |
Prospective Descriptive Study of Injuries Associated to Anterior Shoulder Dislocations in Patients Over 40 Years

Study Overview
=================
Brief Summary
-----------------
The glenohumeral joint has the highest rate of dislocation of the whole body, due to its high mobility and the special characteristics of its anatomy. It is estimated that every year between 1-2% of the population will suffer from glenohumeral dislocation. The vast majority of studies are based on young patients under the age of 40, given that at this age they have the higher incidence and at the same time, they have higher redislocation index. However, the investigators are in front of a more active population with a longer life expectancy. That is why the cases of anterior glenohumeral dislocations are increasing in people older than 40 years. Given that most studies focus on younger patients, the investigators lack knowledge about which injuries are associated with dislocation at this age and whether these influence its clinical evolution.

Official Title
-----------------
Prospective Descriptive Study of Injuries Associated to Anterior Shoulder Dislocations in Patients Over 40 Years

Conditions
-----------------
Anterior Glenohumeral Dislocations

Intervention / Treatment
-----------------
* Procedure: Reduction


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: More than 40 years old First episode of traumatic anterior gelnohumeral dislocation seen in Rx Acceptance to be checked over 2 years Acceptance to be submitted to TAC, NMR, EMG and Bilateral Ultrasound Exclusion Criteria: Previous fractures in this extremity Previous neurovascular lesions in this extremity Other associated lesions Cognitive alterations or dementia which prevent completing the protocols. Patients with <14 points in Mini-mental test.

Ages Eligible for Study
-----------------
Minimum Age: 40 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Humeral anterior dislocation<br>Patients presenting a first episode of humeral anterior dislocation and who are over 40 years old. | Procedure: Reduction<br>* An Rx will be performed before and after the reduction of the dislocation. After that, the neurovascular state will be checked and also if there is some associated injury.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Characterization of associated lesions |  | At the three months visit including assessment of NMR/EMG/TAC/Bilateral Ultrasound | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Constant Functional Test |  | 3, 6, 12 and 24 months | 
| WOSI test |  | 3, 6, 12 and 24 months | 
| SST |  | 3, 6, 12 and 24 months | 
| Redislocations |  | 3, 6, 12 and 24 months | 
| Type of treatment |  | 3, 6, 12 and 24 months |