The Impact of Pericardial Closure on the Grafts, in the Context of Coronary Artery Bypass Grafting

Study Overview
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Brief Summary
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Once the pericardium is closed, there is no information on the hemodynamics of the grafts after coronary artery bypass grafting. This would be the reason for different opinions on pericardial closure: some teams do not close the pericardium and others close it. In the department Cardiovascular Surgery of the University Hospital of Saint-Etienne, the Medistim machine is used in routine and the hemodynamic properties of the grafts are recorded immediately after the bypass surgery, before the closure of the pericardium.

Detailed Description
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The aim of the study is to have hemodynamic information immediately after the closure of the pericardium using the Medistim machine. The prospective study will be conducted on 50 patients, who will be selected consecutively without randomization. The inclusion and exclusion criteria are determined.

Official Title
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The Impact of Pericardial Closure on the Grafts, in the Context of Coronary Artery Bypass Grafting

Conditions
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Bypass Graft Stenosis

Intervention / Treatment
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* Other: Datas of Medistim machine


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All patients who will have isolated aortocoronary bypass grafting surgery Exclusion Criteria: History of thoracic trauma Severe cyphosis Severe thoracic deformity (Pectus excavatum) Pericardial disease History of radiotherapy Severe pulmonary disease (emphysema) Right heart failure Redo surgery

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients who will have isolated aortocoronary bypass grafting surgery<br>Patients who will have isolated aortocoronary bypass grafting surgery will be included. The Medistim machine will be use before and after pericardial closure. Datas will be collected and analysis. | Other: Datas of Medistim machine<br>* Datas will be collected by Medistim machine before and after pericardial closure: Flow through the grafts, Resistance on grafts, Pulsatility of the grafts, Systolic and diastolic curves before and after pericardial closure<br>* Other names: Medistim machine;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Flow through the grafts | Datas will be collected by Medistim machine. | Minute : 1, 15 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Resistance on grafts | Datas will be collected by Medistim machine. | Minute : 1, 15 | 
| Pulsatility of the grafts | Datas will be collected by Medistim machine. | Minute : 1, 15 | 
| Systolic curves | Datas will be collected by Medistim machine. | Minute : 1, 15 | 
| Diastolic curves | Datas will be collected by Medistim machine. | Minute : 1, 15 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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grafts, Cardiac surgery, pericardial closure, bypass, aortocoronary bypass