DBT Skills Expanded With Contextual Intervention for Long Lasting Symptoms in Borderline Personality Disorder

Study Overview
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Brief Summary
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Although borderline personality disorder (BPD) tend to the clinical remission in long-term follow-up studies, a significant subgroup of patients continues to present long lasting symptoms such as low mood, emptiness and persistent impairment in psychosocial adjustment. The prevalence of this subsample of individuals is considerably increasing last years. New interventions addressed to these individuals are need, the aim of this study is to evaluate the efficacy of a novel intervention combining dialectical behavioral therapy skills training with self-compassion and contextual-based skills for patients with long-lasting BPD.

Detailed Description
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Sixty individuals with BPD and long lasting symptoms that have been received previously dialectical-behavioral therapy skills training (DBT-ST) will be included in a randomized clinical trial. They will be randomly assigned to receive an add-on skills training intervention involving the combination of DBT-ST, self-compassion, and contextual-based skills for long lasting symptoms versus treatment as usual during 12-weeks. Patients will be evaluated pre and post intervention and 3-month follow-up. The outcome measures are well-being indicators and clinical variables.

Official Title
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Clinical Trial of Skills Training for Long Lasting Symptoms in Borderline Personality Disorder

Conditions
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Borderline Personality Disorders, BPD

Intervention / Treatment
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* Behavioral: Combination DBT, self-compassion and contextual-based skills


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adults between 18 and 65 years of age Primary diagnosis of BPD according to Diagnostic Statistical Manual IV criteria and by the structured interviews: Diagnosis Structured clinical interview for axis II personality disorders (SCID II; First et al. 1997) and Diagnostic Interview for Borderlines Revised (DIB-R) Previous participation in DBT-ST intervention Signed informed consent. Exclusion Criteria: Presence of life-threatening behaviors in the last 12 months PTSD or related symptoms Diagnosis of drug-induced psychosis, organic brain syndrome, bipolar or psychotic disorder Intellectual disability Participation in any other psychotherapy treatment during the study.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Randomized clinical trial aims to test the efficacy of this expanded skills DBT-based intervention with self-compassion and contextual-based skills targeting long-lasting BPD compared with treatment as usual.
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Combination of DBT-ST, self-compassion, and contextual-based skills.<br>Combination of DBT-ST, self-compassion, and contextual-based skills. | Behavioral: Combination DBT, self-compassion and contextual-based skills<br>* Psychotherapy combination. Skills of DBT plus self-compassion and contextual skills<br>|
| Placebo Comparator: Control Group<br>Treatment as usual. Although these individuals did not receive any new specific psychotherapeutic intervention for BPD, they valued the higher frequency of psychiatric visits, attention in crisis, family care, and greater experience and sensitivity in the management of BPD. | Behavioral: Combination DBT, self-compassion and contextual-based skills<br>* Psychotherapy combination. Skills of DBT plus self-compassion and contextual skills<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pemberton Happiness Index (PHI) | Happiness index (minimum 0- maximum 110) Higher scores better | 1 month | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Borderline Symptoms List-23 (BSL-23) | Symptoms of Borderline (minimum 0- maximum 92). Higher scores worse | 1 week | 
| Remission from Depression Questionnaire (RDQ) | Depression (minimum 0- maximum 84). Higher scores worse | 1 week | 
| Self Compassion Scale Short Form (SCS-SF) | Compassion scale (12 items, minimum 12- maximum 60). Higher scores worse | 1 month | 
| Forms of Self-Criticism/Self-Attacking and Self-Reassuring Scale (FSCRS) | Self-criticism forms (14 items, minimum 0- maximum 56). Higher scores worse | 1 month | 
| Satisfaction with life scale (SWLS) | Well being (5 items, minimum 5 - maximum 25). Higher scores better | 1 month | 
| Quality of life scale (WHO-QOL_BREF) | Quality of life OMS (26 items, minimum 26- maximum 130). Higher scores better | 2 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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borderline personality disorder, long-lasting symptoms, dialectical behavior therapy skills, contextual approach.