Placenta, Fetal Liver, Sectional Ductus Venosus Volumes Examined by Three-dimensional Ultrasound in the Second Trimester

Study Overview
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Brief Summary
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Investigators measured the placenta, fetal liver and ductus venosus volumes of pregnant women with GDM diagnosis and normal glycemic indices in the second trimester.Investigators aimed to correlate measurements with maternal/fetal outcomes and evaluate their success in predicting poor obstetric outcomes

Detailed Description
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GDM screening may not always be possible with OGTT performed in limited weeks of gestation. In addition, mid-trimester ultrasound scanning is done in all pregnancies. Therefore, measurement of placental volume and fetal liver volume may be an alternative method for the diagnosis of GDM. In order to predict GDM in the second trimester, the use of 3D sonography and VOCAL (Virtual Organ Computer Aided Analysis) technology in high-risk pregnant women and their cost-effectiveness rates should be investigated further. Multicenter randomized controlled studies with more patients are needed to be able to say more clearly.

Official Title
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The Role of Placenta, Fetal Liver, Sectional Ductus Venosus Volumes Examined by Three-dimensional Ultrasound in the Second Trimester in Predicting Gestational Diabetes Mellitus and Maternal-fetal Outcomes

Conditions
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Gestational Diabetes, DUCTUS VENOSUS VOLUME, PLACENTA VOLUME, 3D SONOGRAPHY, FETAL LİVER VOLUME

Intervention / Treatment
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* Other: 3D sonography


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: singleton pregnancy diagnosed with GDM Exclusion Criteria: multiple pregnancy congenital anomalies gestational hypertansion preeclampsia

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Intervention Model: Single Group Assignment
Interventional Model Description: 46 pregnant women diagnosed with gestational diabetes mellitus, 93 pregnant women with normal glycemic index
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: placenta, fetal liver, sectional ductus venosus volumes between 24-29 weeks pregnant women<br>The placenta, fetal liver and ductus venosus volumes of 46 patients diagnosed with GDM and 93 patients without a GDM diagnosis between 24-29 weeks were evaluated with 3D ultrasound. | Other: 3D sonography<br>* Fetal liver, placenta, and ductus venosus were defined in 3 orthogonal multi-plane images in the voluson 4D view vocal program.<br>* Other names: 3D volume description;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Placenta volume in ultrasound | Measured placenta volumes of pregnant women with GDM diagnosis and normal glycemic indices and evaluate their success in predicting poor obstetrics outcomes | 10 months | 
| Fetal liver volume in ultrasound | Measured fetal liver and ductus venosus volumes of pregnant women with GDM diagnosis and normal glycemic indices and evaluate their success in predicting poor obstetrics outcomes | 10 months | 
| Ductus venosus volume in ultrasound | Measured ductus venosus volumes of pregnant women with GDM diagnosis and normal glycemic indices and evaluate their success in predicting poor obstetrics outcomes | 10 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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GESTATİONAL DİABETES MELLİTUS, PLACENTA VOLUME, FETAL LİVER VOLUME, DUCTUS VENOSUS VOLUME, 3D SONUGRAPHY