Optimal Effective Local Anesthetic Volume for Pain Relief Using Brachial Plexus Block

Study Overview
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Brief Summary
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Prospective, patient-blinded study utilizing a novel Continuous Reassessment Method that concomitantly considers both block success and block side effects (lung dysfunction) for brachial plexus nerve blocks.

Detailed Description
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Success or failure of the brachial plexus block for any given volume will be determined by the verbal analogue pain scale score obtained 60 minutes after surgical end time. Volumes will be determined by continuous reassessment method.

Official Title
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Optimal Effective Local Anesthetic Volume for Pain Relief Using Brachial Plexus Block Utilizing Continuous Reassessment Method for Arthroscopic Rotator Cuff Shoulder Surgery

Conditions
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Post Operative Pain

Intervention / Treatment
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* Drug: Dose of 0.5% Ropivacaine


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Surgical candidate for Arthroscopic rotator cuff surgery ASA I-III BMI<40 Age >18 Exclusion Criteria: Inability to give informed consent Inability to complete consent process in English allergy to ropivacaine neuropathy contraindications to peripheral nerve block per ASRA guidelines chronic opioid use infection at the injection/catheter site limb restriction due to medical history history of moderate - severe lung disease.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Brachial Plexus Block Group 1<br>Interscalene | Drug: Dose of 0.5% Ropivacaine<br>* Dose varied by 5mL of 0.5% Ropivacaine<br>|
| Experimental: Brachial Plexus Group 2<br>Supraclavicular | Drug: Dose of 0.5% Ropivacaine<br>* Dose varied by 5mL of 0.5% Ropivacaine<br>|
| Experimental: Brachial Plexus Group 3<br>Suprascapular | Drug: Dose of 0.5% Ropivacaine<br>* Dose varied by 5mL of 0.5% Ropivacaine<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Block Success | Block success measured by pain (11-point VAS) | 60min after surgery | 
| Lung Function | Block success as measured by preservation of lung function (Vital Capacity in L) | 60 mins after surgery | 
| Block Success | Block Success measured by opioid (mcg of fentanyl delivered) | 60 mins after surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Diaphragm Excursion | Change in Movement of Diaphragm in cm | 60 minutes after surgery | 
| Vital Capacity | Change in Vital Capacity measured in L | 60 minutes after surgery | 
| Pulse Oximetry | Change in Pulse Oximetry Value | 60 minutes after surgery | 
| Side Effects | Rate of Dyspnea, Horner's, Hoarseness | 60 minutes after surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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brachial plexus block