linjc16/ctgov huggingface dataset:
Complications of Enterocystoplasty in Children

Study Overview
=================
Brief Summary
-----------------
The goal of this observational study is to describe the complications in participants who underwent enterocystoplasty in childhood. The main question[s] it aims to answer are: what kind of complications are there the kind of complications depending on the type of enterocystoplasty Participants data will be collected in the medical field. There is no comparison group.

Detailed Description
-----------------
From 1982 to 2020, all patients who had an enterocystoplasty in childhood were collected. Complications were numbered depending on the type of enterocystoplasty and the investigators tried to find which risk factors exist.

Official Title
-----------------
Surgical Complications of Enterocystoplasty in Children: A Retrospective Monocentric Study About 39 Cases

Conditions
-----------------
Complications of Surgical Procedure, Neurogenic Bladder, Spina Bifida, Child, Only

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients who underwent a enterocystoplasty before 18 years old Exclusion Criteria: patients who underwent a enterocystoplasty after 18 years old

Ages Eligible for Study
-----------------
Minimum Age: 0 Years
Maximum Age: 17 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Surgical complications of bladder augmentation in children depending on the type of enterocystoplasty | Observational study | 38 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Impact of the participants' age on the occurrence of complications depending on the type of enterocystoplasty | Observational study | 38 years | 
| Impact of the participants' sex on the occurrence of complications depending on the type of enterocystoplasty | Observational study | 38 years | 
| Impact of the participants' type of neurogenic bladder on the occurrence of complications depending on the type of enterocystoplasty | Observational study: the participants can have spina bifida, bladder exstrophy, anorectal malformation and if it has an impact on the occurrence of complications depending on the type of enterocystoplasty | 38 years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Augmentation Enterocystoplasty, Surgical Complications, Children, Retrospective Study
Comparison of Nipple-areolar Complex Sensation According to Incision Types in Nipple-sparing Mastectomy

Study Overview
=================
Brief Summary
-----------------
This study aims to assess nipple areolar complex sensation after nipple sparing mastectomy and compare the results according to different incisional approaches; specifically, inframammary fold (IMF) versus peri-areolar/radial. One-hundred-and-five post NSM patients from Oct 2019 to Nov 2021 have been recruited prospectively and evaluated for NAC sensory. A total of 97 patients (IMF 65 and peri-areolar/radial 32) were included in the analyses for comparison during follow up from 24 to 48 months after surgery. It was hypothesized that patients with IMF would have better outcomes for NAC senroy.

Official Title
-----------------
Comparison of Nipple-areolar Complex Sensation According to Incision Types in Nipple-sparing Mastectomy

Conditions
-----------------
Breast Cancer, Nipple Sparing Mastectomy

Intervention / Treatment
-----------------
* Biological: Nipple sparing mastecomy with different incision placements


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Females who are older than 18 Patients who underwent nipple sparing mastectomy in Gangnam Severance Hospital Exclusion Criteria: Loss or excision of NAC due to post-surgical necrosis Diagnosis of other conditions that may interfere with cutaneous sensation

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Imframammary<br>Imframammary- NSM using imframammary incision | Biological: Nipple sparing mastecomy with different incision placements<br>* Nipple sparing mastectomy was performed using Radial/Peri-areolar incision or imframammary incision<br>|
| Radial/Peri-areolar<br>Radial/Peri-areolar- NSM using Radial/Peri-areolar incision | Biological: Nipple sparing mastecomy with different incision placements<br>* Nipple sparing mastectomy was performed using Radial/Peri-areolar incision or imframammary incision<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Loss of NAC sensory by pinprick test | Difference in NAC sensory loss between the patients with two different incisions. | 2-4 years after surgery | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
NAC sensory, Mastectomy, NSM
Effect of Ketogenic Diet on Muscle Hypertrophy

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to investigate the effects of 4 weeks of carbohydrate deprivation (through a ketogenic diet) on hypertrophy signalling after a single bout of exercise in healthy trained male subjects, and the impact on body composition, muscle strength, and blood parameters.

Official Title
-----------------
Effects of Ketogenic Diet on Muscle Hypertrophic Response to Resistance Exercise

Conditions
-----------------
Healthy Nutrition

Intervention / Treatment
-----------------
* Other: resistance training
* Other: ketogenic diet
* Other: western diet


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: at least 2 years of resistance-training experience Body mass index: more than 18 kg/m2 and less than 30 kg/m2 Exclusion Criteria: metabolic diseases or noncommunicable diseases (cardiovascular, liver, respiratory, cancer, etc) experience with the ketogenic diet (last six months) acute inflammatory status treatment with steroids in the past 3 months

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 50 Years

Sexes Eligible for Study
-----------------
Male

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: ketogenic diet<br>Participants will perform a single exercise bout after 4 weeks of resistance training combined with a ketogenic diet (KD group). | Other: resistance training<br>* All participants perform a four-day resistance training aimed to stimulate a hypertrophic response.<br>Other: ketogenic diet<br>* Subjects allocated to the ketogenic diet arm (KD group) consume less than 50 g of carbohydrates per day.<br>|
| Active Comparator: western diet<br>Participants will perform a single exercise bout after 4 weeks of resistance training combined with a western diet (WD group). | Other: resistance training<br>* All participants perform a four-day resistance training aimed to stimulate a hypertrophic response.<br>Other: western diet<br>* Subjects allocated to the western diet arm (WD group) consume a standard diet based on 55% of their daily calories from carbohydrates.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| mammalian target of rapamycin (mTOR) signalling | Measurement of the change in muscle protein anabolic signalling pathway in response to a single bout of resistance exercise by western blot analysis. | Change from baseline to 4 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Skeletal muscle mass | Measurement of the change in kilograms of muscle mass via Dexa | Change from baseline to 4 weeks |
ARISCAT and LAS VEGUS Risk Scores for Predicting Postoperative Pulmonary Complications After Cardiac Surgery

Study Overview
=================
Brief Summary
-----------------
The goal of this observational study is to compare the, ARISCAT and LAS VEGUS scales, for predicting postoperative pulmonary complications in patients undergoing cardiac surgery. The study aims to compare the diagnostic accuracies of the two risk prediction scores in predicting postoperative pulmonary complications.

Official Title
-----------------
ARISCAT and LAS VEGUS Risk Scores for Predicting Postoperative Pulmonary Complications After Cardiac Surgery

Conditions
-----------------
Pulmonary Complication, Postoperative Complications, Postoperative Pulmonary Complications

Intervention / Treatment
-----------------
* Diagnostic Test: Detection/screening


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients undergoing elective heart surgery Exclusion Criteria: Refusal to consent Patients undergoing emergency surgery

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Adult In-patient Cardiac surgery<br>Adult patients undergoing elective open-heart surgery | Diagnostic Test: Detection/screening<br>* Using ARISCAT and LAS VEGUS risk scores for predicting PPCs<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative Pulmonary Complications | ARISCAT AND LAS VEGAS Scoring systems will be used to predict postoperative pulmonary complications. | Day 1-5 |
Surgical Margin Assessment by 3D Ultrasound

Study Overview
=================
Brief Summary
-----------------
Complete removal of cancer encircled by a secure margin of healthy tissue is the aim of surgical oncology. A close or positive surgical margin reported by pathologist typically ends in adjuvant therapies (re-surgery and/or radiotherapy), which come with prognostic risks and financial cost. Therefore, ex-vivo imaging of removed cancer tissue may assist in margin evaluation. In this study, investigators aimed to investigate the correlation of 3D ultrasound to histopathology to assess tongue tumor margin status.

Official Title
-----------------
Feasibility of 3D Ultrasound in the Assessment of Resection Margins During Surgery for Squamous Cell Carcinoma of the Tongue: a Comparison With Histopathology

Conditions
-----------------
Tongue Cancer, Squamous Cell Carcinoma, Head and Neck Cancer

Intervention / Treatment
-----------------
* Diagnostic Test: 3D ultrasound


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with biopsy-proven oral tongue squamous cell carcinoma scheduled for surgical treatment T1-T2 staging on cross-sectional imaging Exclusion Criteria: Age < 18 yrs T3-T4 staging Unable to understand the verbal or written information Prior radiotherapy treatment of oral cavity cancer

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Tongue tumor resection<br> | Diagnostic Test: 3D ultrasound<br>* 3D ultrasound scanning of the resected tongue tumor will be performed. The margin analysis will be made using the 3D ultrasound image.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Correlation of the surgical margin measurements of the 3D ultrasound to histopathology | The smallest margin will be measured in mm on 3D ultrasound image of the ex-vivo surgical specimen. Correlation of the measurement to the final histopathology result will be investigated. | 2 weeks | 
| Diagnostic accuracy | number of margins correctly classified as free (> 5 mm), close (< 5 mm) or positive (<1 mm) margin | 2 weeks | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
3D ultrasound, Histopathology, Ultrasonography, Three dimensional imaging, cancer diagnosis, tongue tumor
A Retrospective Cohort Study of HFRS

Study Overview
=================
Brief Summary
-----------------
The goal of this retrospective cohort study is to learn about the clinial characteristics of HFRS patients, explore the risk factors of the occurrence and death of HFRS, and build a risk prediction model for HFRS.

Detailed Description
-----------------
HFRS remains an important public health issue in China, which not only poses a threat to people's physical health and safety, but also has a serious impact on social and economic development. At present, there is no unified standard for clinical prediction of the occurrence and death of HFRS. In order to better prevent and treat HFRS, this multicenter retrospective clinical study is designed to include HFRS inpatients, and collect their demographics, epidemiological history, hospitalization information, clinical manifestation, laboratory results, imaging results, treatment plan and outcome.

Official Title
-----------------
A Retrospective Cohort Study of Hemorrhagic Fever With Renal Syndrome

Conditions
-----------------
HFRS

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: The patients must meet all of the following criteria: Inpatient with clinical diagnosis of Haemorrhagic Fever with Renal Syndrome Exclusion Criteria: Exclude patients who meet any of the following criteria: Patients with previous chronic kidney disease Pregnant or perinatal patients Patients unsuitable for inclusion by investigators' evaluation

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| short-term mortality | 28-day and 90-day mortality after diagnosed as HFRS | 90 days post diagnosed HFRS |
Successful Microsurgical Breast Reconstruction in Minimally Invasive Mastectomy

Study Overview
=================
Brief Summary
-----------------
A retrospective chart review will be conducted to identify patients who received breast reconstruction surgery with DIEP flaps by a single plastic surgeon in one medical center between November 2018 and July 2022. Patients will be grouped based on how the mastectomy was performed, via minimally invasive or conventional approach. Demographic data, flap profile, vessel anastomosis and post-operative complication will be retrospectively reviewed. Data collection includes patient demographics, previous breast surgical history, breast cancer history and adjuvant therapy, surgical details and postoperative events.

Official Title
-----------------
Six Steps for a Successful Aesthetic Free Flap Reconstruction Shaping After Minimally Invasive Mastectomy

Conditions
-----------------
Breast Reconstruction, Breast Cancer

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients who received nipple sparing mastectomy and breast reconstruction from November 2018 to July 2022 from a single breast reconstruction surgeon. Exclusion Criteria: patients failed to be examined for outcome evaluation will be excluded from the study.
Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Control<br>Conventional mastectomy | |
| Minimally invasive<br>robotic-assisted or endoscopic assisted mastectomies | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Successful | If the free flap transferred is successfully survived | post-operative 7 days | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
free flap, breast reconstruction, minimally invasive mastectomy, nipple-sparing mastectomy, robotic-assisted mastectomy, endoscopic-assisted mastectomy
Studying Patterns in Patient Engagement Among Treatment Resistant Depression Patients

Study Overview
=================
Brief Summary
-----------------
Clinical studies, with a distinct focus on treatment resistant depression, play a crucial role in evaluating the safety and effectiveness of novel treatments. These trials serve as instrumental means to determine whether new medications surpass conventional therapies, providing substantial evidence for their broader adoption. The primary objective is to meticulously scrutinize trial completion rates and voluntary withdrawals within this specific patient group.

Official Title
-----------------
Evaluating the Occurrence of Engagement Patterns and Participation Trends Among Patients in Treatment Resistant Depression

Conditions
-----------------
Treatment Resistant Depression

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Diagnosis of treatment resistant depression Aged ≥ 18 years old and ability to provide written informed consent obtained prior to participation in the study and any related procedures being performed No prior treatment for treatment resistant depression Exclusion Criteria: Enrolled in another research study Inability to provide written informed consent Has known psychiatric or substance abuse disorders that would interfere with cooperation with the requirements of the trial

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rate of patients who decide to enroll in a treatment resistant depression clinical research. |  | 3 months | 
| Number of treatment resistant depression study participants who remain in clinical study until completion. |  | 12 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
treatment resistant depression
Theory of Mind in Children With DCD

Study Overview
=================
Brief Summary
-----------------
The aim of the study is to investigate theory of mind (ToM) in children with developmental coordination disorder (DCD). Dutch-speaking children, who are living in Flanders or The Netherlands (because comparisons will be made with Flemish and Dutch norms), will be included. In addition, children should be six until twelve years old with a DCD diagnosis confirmed by a multidisciplinary team (including a doctor). During the test moment, ToM will be tested by ToM test-R and the motor skills by MABC-2. Beside, the ToM test-R will be filmed, but the child's face not shown. The parent/legal guardian will be asked to complete five online questionnaires (demographic and developmental questionnaire, CVO, SRS-2, SDQ and ToMBC), this can be completed in advance at home or at the test moment (researchers provide a laptop).

Official Title
-----------------
Theory of Mind in Children With DCD

Conditions
-----------------
Developmental Coordination Disorder

Intervention / Treatment
-----------------
* Behavioral: Assessment


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age of child: from six to 12 years old Confirmed diagnosis of DCD by a multidisciplinary team (including a physician) Child lives in Flanders or the Netherlands Child has Dutch as the mother tongue Exclusion Criteria: Diagnosis of autism spectrum disorder (ASD) Blood related siblings of the child Parent/legal guardian does not have an adequate level of Dutch (IQ lower than 70) OR (no IQ information and child attends special education type 1 (mild intellectual disability) or type 2 (moderate to severe mental disability))

Ages Eligible for Study
-----------------
Minimum Age: 6 Years
Maximum Age: 12 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Screening
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Children with DCD<br> | Behavioral: Assessment<br>* Observations using two valid, observational instruments (MABC-2 and ToM test-R) that each child completes once at random. A demographic and developmental questionnaire is completed once by the parent/guardian at recruitment. Standardized questionnaires (Coordination Questionnaire For Parents (CVO), Social Responsiveness Scale second edition (SRS-2), Strengths and Difficulties Questionnaire (SDQ) and Theory of Mind Behavior Checklist (ToMBC)) are also questioned once to parent/guardian for data collection.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Theory of Mind | Measured with ToM test-R andTheory of Mind Behavior Checklist (ToMBC) | 2 hours | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Child, Development, Theory of mind