Erector Spinae Plane Block for Postoperative Pain Management

Study Overview
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Brief Summary
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Erector spinae plane (ESP) block is an interfacial plane block with visceral and somatic analgesic activity at paraspinal muscles. This study aims to examine the postoperative analgesic efficacy of ESP block after cesarean section (CS) with Pfannenstiel incision under spinal anesthesia.

Detailed Description
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The study included 54 patients with mild systemic disease (ASA II patients) who would undergo elective CS under spinal anesthesia. They were randomly divided into an ESP block group (Group E) and a control group (Group C). After the surgery, Group E patients underwent ultrasound-guided bilateral ESP block with 20 ml of 0.25% bupivacaine at the lateral decubitus position, while Group C received no intervention. Patients in both groups received parenteral patient-controlled analgesia. The patients' post-operative 24-hour opioid consumption, regular Visual Analogue Scale (VAS) measurements, and need for rescue analgesics were evaluated. Statistical analysis was performed using SPSS 21 program. Demographic and other data were assessed using independent samples t-test, Mann-Whitney U test, and Chi-square analysis.

Official Title
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The Effect of Erector Spinae Block for Postoperative Pain Management Cesarean Delivery Patients

Conditions
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Pain, Post Operative Pain

Intervention / Treatment
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* Procedure: Control
* Procedure: Erector spinae plane block


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: ASA II patients 18-45 years who underwent CS with Pfannenstiel incision under spinal anesthesia agreed to participate in the study Exclusion Criteria: Patients with infection at the injection site Coagulopathy Allergy to amide-type local anesthetics History of peripheral neuropathy Hepatic and/or renal failure Refusing the procedure patients with heart disease

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Sham Comparator: Control group<br>No block was performed, tramadol was administered with patient-controlled analgesia (PCA) and all patients were followed in the ward. | Procedure: Control<br>* No block was performed<br>|
| Active Comparator: Erector spinae plane block<br>Erector spinae plane block was performed, tramadol was administered with patient-controlled analgesia (PCA) and all patients were followed in the ward. | Procedure: Erector spinae plane block<br>* Erector spinae plane block was performed, tramadol was administered with patient-controlled analgesia (PCA) and all patients were followed in the ward.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 24-hour opioid consumption | The amount of tramadol consumed in milligrams in the first 24 hours was determined with a patient-controlled analgesia pump. | up to 24 hour | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual Analog Scale (Vas) | pain scores,graded from 0 to 10, 0 no pain, 10 highest pain experienced | 0, 30 minutes, 1 hour, 2 hours, 6 hours, 12 hours, 24 hours | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Pain, postoperative analgesia, Erector spinae plane block, cesarean section