Cognitive, Emotional, Communicative, and Motor Development in Children Born From IOC

Study Overview
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Brief Summary
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The study focuses on children born after in vitro fertilization (IVF) of cryopreserved oocytes.

Detailed Description
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Evaluate whether the cognitive development of children born by IVF of cryopreserved oocytes is comparable to expected peer development. Evaluate whether the emotional development of children born by IVF of cryopreserved oocytes is comparable to expected peer development. Evaluate whether the communicative development of children born by IVF of cryopreserved oocytes is comparable to expected peer development. Evaluate whether the motor development of children born by IVF of cryopreserved oocytes is comparable to expected peer development

Official Title
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Cognitive, Emotional, Communicative, and Motor Development in Children Born From in Vitro Fertilization of Cryopreserved Oocytes

Conditions
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ART, Child Development

Intervention / Treatment
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* Other: Phone contact


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Live births from pregnancies resulted from fresh and frozen embryo transfer after fertilization of cryopreserved oocytes are included. Exclusion Criteria: Children born from pregnancies obtained from cryopreserved donated oocytes have been excluded.
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| CHILDREN<br>BORN FROM IN VITRO FERTILIZATION OF CRYOPRESERVED OOCYTES | Other: Phone contact<br>* . All mothers of children of born from cryopreserved oocytes will be contacted by phone and administered a questionnaire, to gather additional information about further psychomotor development of children.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cognitive development | Evaluation through a newly edited questionnaire according to milestones, set for age, established by CDC guidelines (Zubler et al, 2022). The objective is to compare cognitive development of children born by IVF of cryopreserved oocytes in comparison to expected peer development. Answers will be reported as yes/no according if milestones are achieved or not. | 18 YEARS | 
| Communicative development | Evaluation through a newly edited questionnaire according to milestones, set for age, established by CDC guidelines (Zubler et al, 2022). The objective is to compare communicative development of children born by IVF of cryopreserved oocytes in comparison to expected peer development. Answers will be reported as yes/no according if milestones are achieved or not. | 18 YEARS | 
| Motor development | Evaluation through a newly edited questionnaire according to milestones, set for age, established by CDC guidelines (Zubler et al, 2022). The objective is to compare motor development of children born by IVF of cryopreserved oocytes in comparison to expected peer development. Answers will be reported as yes/no according if milestones are achieved or not. | 18 YEARS | 
| Emotional development | Evaluation through a newly edited questionnaire according to milestones, set for age, established by CDC guidelines (Zubler et al, 2022). The objective is to compare emotional development of children born by IVF of cryopreserved oocytes in comparison to expected peer development. Answers will be reported as yes/no according if milestones are achieved or not. | 18 YEARS |