Efficacy Testing of Melon Oil Olive Pressed Candy Products

Study Overview
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Brief Summary
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To assess melon and oil olive pressed candy on skin condition improvement

Official Title
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Efficacy Testing of Melon Oil Olive Pressed Candy Products

Conditions
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Skin Condition

Intervention / Treatment
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* Dietary Supplement: Placebo candy
* Dietary Supplement: melon and oil olive pressed candy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Healthy adults aged above 18 years old ITA° value 20°-41° Exclusion Criteria: Involuntary subjects. Subjects who have a history of skin diseases such as psoriasis, eczema, atopic dermatitis, severe acne; or suffer from other chronic systemic disease. Those with known cosmetic, drug or food allergies. Female who is pregnant or nursing or planning to become pregnant during the course of the study. Subjects who have taken oral or topical corticosteroids and other anti-inflammatory drugs in the past 1 month. Use of any products or drugs that affect skin color such as fruit acid, salicylic acid (such as Hydroquinone preparations) in the past 2 months. In the past 3 months, the test site has used retinoic acid preparations or undergone chemical peeling, laser, pulse light and other medical aesthetic therapists Subjects who can not avoid long-term sun exposure

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Placebo Comparator: Placebo candy<br> | Dietary Supplement: Placebo candy<br>* consume 2 tablets per day<br>|
| Experimental: melon and oil olive pressed candy<br> | Dietary Supplement: melon and oil olive pressed candy<br>* consume 2 tablets per day<br>* Other names: Melon, oil olive and pomegranate blend pressed candy;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The change of skin wrinkles | VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units | Change from Baseline skin wrinkles at 12 weeks | 
| The change of skin texture | VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units | Change from Baseline skin texture at 12 weeks | 
| The change of skin melanin index | Mexameter® MX18 was utilized to measure skin melanin index. Units: arbitrary units | Change from Baseline skin melanin index at 12 weeks | 
| The change of skin erythema index | Mexameter® MX18 was utilized to measure skin erythema index. Units: arbitrary units | Change from Baseline skin erythema index at 12 weeks | 
| The change of skin L* value | Chroma Meter MM500 was utilized to measure skin L* value. Units: arbitrary units | Change from Baseline L* value at 12 weeks | 
| The change of skin b* value | Chroma Meter MM500 was utilized to measure skin b* value. Units: arbitrary units | Change from Baseline b* value at 12 weeks | 
| The change of skin ITA° value | Chroma Meter MM500 was utilized to measure skin ITA° value. Units: arbitrary units | Change from Baseline ITA° value at 12 weeks | 
| The change of skin spots | VISIA Complexion Analysis System was utilized to measure skin spots. Units: arbitrary units | Change from Baseline skin spots at 12 weeks | 
| The change of skin UV spots | VISIA Complexion Analysis System was utilized to measure skin UV spots. Units: arbitrary units | Change from Baseline skin UV spots at 12 weeks | 
| The change of skin brown spots | VISIA Complexion Analysis System was utilized to measure skin brown spots. Units: arbitrary units | Change from Baseline skin brown spots at 12 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The change of TEAC of blood | Venous blood was sampled to measure TEAC | Change from Baseline TEAC at 12 weeks | 
| The change of SOD of blood | Venous blood was sampled to measure SOD | Change from Baseline SOD at 12 weeks | 
| The change of GSH-Px of blood | Venous blood was sampled to measure GSH-Px | Change from Baseline GSH-Px at 12 weeks |