Hypnosis: a Path to Appeasement

Study Overview
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Brief Summary
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Hypnosis is a technique allowing the patient to focus his mental attention on a thought or a sensation, with the aim of reducing or modulating the intensity of a negative feeling or an ordeal encountered during the course of treatment. This tool can be used when patients are faced with chronic disorders (pain, anxiety, ...) or iatrogenic effects (nausea, asthenia, ...). The patient is referred to hypnosis care by the doctor, psychologist or paramedics who follow him, when they detect a need. Several scientific studies have shown the effectiveness of hypnosis in improving the quality of life of patients with breast cancer and in reducing pain during invasive procedures. On the other hand, in hematology, no research has measured the evolution of anxiety, over time, in patients receiving hypnotherapy.

Official Title
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Hypnosis: a Path to Appeasement

Conditions
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Hematologic Cancer

Intervention / Treatment
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* Other: anxiety questionnaire


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients over 18 years old, fluent in French. Patients starting hypnotherapy for anxiety disorders. Anxiety score on the HADS scale (Hospital Anxiety and Depression Scale) greater than or equal to 8/21 Patients with diffuse large cell B-cell lymphoma or follicular lymphoma, whatever the stage of the disease. Diagnosis announcement less than 2 months old Exclusion Criteria: Persons deprived of their liberty by a judicial or administrative decision Adults subject to a legal protection measure

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Anxiety scores<br> | Other: anxiety questionnaire<br>* Patient undergoing hypnosis session will have their anxiety measured just before the third session of hypnosis and after during a telephonic consultation. The result will be compared to the anxiety level before the first hypnosis session<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evolution of anxiety | Difference in anxiety measured before starting hypnotherapy care and after 2 hypnosis sessions. It will be measured by the Hospital Anxiety and Depression Scale. This scale gives a score according to the level of anxiety ranging from 0 to 21. The higher the score, the more the patient is anxious. | Week 6 after 2 hypnosis sessions | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evolution of anxiety before hypnotherapy and after 3 months of follow-up in hypnotherapy | Difference in anxiety measured before starting hypnotherapy care and after 3 hypnosis sessions. It will be measured by the Hospital Anxiety and Depression Scale. This scale gives a score according to the level of anxiety ranging from 0 to 21. The higher the score, the more the patient is anxious. | Month 3 after 3 hypnosis sessions | 
| Evolution of anxiety between D0 and M3 according to the type of lymphoma | Difference in anxiety measured before starting hypnotherapy care and after 3 hypnosis sessions for two subgroups : follicular lymphoma and diffuse large b-cell lymphoma. It will be measured by the Hospital Anxiety and Depression Scale. This scale gives a score according to the level of anxiety ranging from 0 to 21. The higher the score, the more the patient is anxious. | Month 3 after 3 hypnosis sessions | 
| Evolution of anxiety between D0 and W6 according to the type of lymphoma | Difference in anxiety measured before starting hypnotherapy care and after 2 hypnosis sessions for two subgroups : follicular lymphoma and diffuse large b-cell lymphoma. It will be measured by the Hospital Anxiety and Depression Scale. This scale gives a score according to the level of anxiety ranging from 0 to 21. The higher the score, the more the patient is anxious. | Week 6 after 2 hypnosis sessions | 
| Evolution of anxiety between D0 and W6 according to the gender of the patient | Difference in anxiety measured before starting hypnotherapy care and after 2 hypnosis sessions for two subgroups : man and woman. It will be measured by the Hospital Anxiety and Depression Scale. This scale gives a score according to the level of anxiety ranging from 0 to 21. The higher the score, the more the patient is anxious. | Week 6 after 2 hypnosis sessions | 
| Evolution of anxiety between D0 and M3 according to the gender of the patient | Difference in anxiety measured before starting hypnotherapy care and after 3 hypnosis sessions for two subgroups : man and woman. It will be measured by the Hospital Anxiety and Depression Scale. This scale gives a score according to the level of anxiety ranging from 0 to 21. The higher the score, the more the patient is anxious. | Month 3 after 3 hypnosis sessions | 
| Evolution of anxiety between D0 and W6 according to age category | Difference in anxiety measured before starting hypnotherapy care and after 2 hypnosis sessions for two subgroups : under 60 years old ans over 60 years old. It will be measured by the Hospital Anxiety and Depression Scale. This scale gives a score according to the level of anxiety ranging from 0 to 21. The higher the score, the more the patient is anxious. | Week 6 after 2 hypnosis sessions | 
| Evolution of anxiety between D0 and M3 according to age category | Difference in anxiety measured before starting hypnotherapy care and after 3 hypnosis sessions for two subgroups : under 60 years old ans over 60 years old. It will be measured by the Hospital Anxiety and Depression Scale. This scale gives a score according to the level of anxiety ranging from 0 to 21. The higher the score, the more the patient is anxious. | Month 3 after 3 hypnosis sessions | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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hypnosis, Diffuse large cell B-cell lymphoma, follicular lymphoma, anxiety