linjc16/ctgov huggingface dataset:
A Study of Overcoming Social Determinants of Health

Study Overview
=================
Brief Summary
-----------------
This study is being done to determine if assistance in accessing community resources can improve health outcomes. Social determinants of health are the conditions in which individuals are born, work and live that can impact health. These can include access to healthcare, healthy food, education, safe neighborhoods, transportation, political and social environments that are safe and fair.

Official Title
-----------------
Social and Relational Capital to Overcome Social Determinants of Health.

Conditions
-----------------
Social Determinants of Health (SDOH)

Intervention / Treatment
-----------------
* Behavioral: The Open Table


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: - Identified social determinants of health (SDOH). need that impacts healthcare outcomes (identified by the healthcare team) Exclusion Criteria: - Non-english speaking patients

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Other
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: The Open Table Model<br>Subjects identified as having their health negatively impacted by Social Determinants of Health (SDOH) will meet with The Open Table members to determine their specific needs, decide on a plan for overcoming this need and following up to ensure resolution. | Behavioral: The Open Table<br>* An organization that connects community volunteers to individuals in need to help overcome life's challenges.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in participant CMS Accountable Health SDOH Screening Assessment | Evaluated using the 10-item CMS Accountable Health SDOH Screening Tool used to access patient needs across 5 core domains that community services can help with including housing instability, food insecurity, transportation problems, utility help needs, and interpersonal safety. | Baseline and 12 months | 
| Change in resilience | Evaluated using the 6-item Brief Resilience Scale (BRS) questionnaire assessing the participants ability to bounce back on a 1-5 scale range. Total questions scores are divided by total number of questions answered for a final score range from 1.00-2.99 = low resilience; 3.00-4.30 = normal resilience; 4.31-5.00 = high resilience. | Baseline and 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Hospitalizations | Total number of hospitalizations | 12 months | 
| Emergency room visits | Total number of emergency room visits | 12 months | 
| Primary care visits | Total number of primary care visits | 12 months |
Efficiency of Determining the Clinical Class of Chronic Venous Disorders by Artificial Intelligence

Study Overview
=================
Brief Summary
-----------------
Purpose: To evaluate the sensitivity and specificity of the method for determining the clinical class of chronic venous diseases using the Ivenus application (within C0-C2 according to CEAP). Materials and methods: Patients who applied to several phlebology clinics for an initial consultation are consistently included in a multicenter prospective study. At the appointment, a doctor with at least 5 years of experience takes photographs of the lower extremities and uploads them to the IVENUS application, which automatically determines the clinical class according to CEAP, without showing the results to the surgeon (blinding). Further, the doctor independently determines the clinical class according to CEAP and enters the data into the register. The object of the study is a photograph of a certain area of the lower limb.

Official Title
-----------------
Efficiency of Determining the Clinical Class of Chronic Venous Disorders by Artificial Intelligence (IVENUS App)

Conditions
-----------------
Varicose Veins of Lower Limb, Telangiectasia

Intervention / Treatment
-----------------
* Diagnostic Test: Determining of the clinical class of chronic venous disorders by artificial intelligence


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: C0-C2 CEAP clinical class; Signed consent to take part in investigation. Exclusion Criteria: C3-C6 CEAP clinical class; Skin diseases of the lower extremities; Immobilization.
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Screening
Intervention Model: Single Group Assignment
Masking: Double


Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: Determining of the clinical class of chronic venous disorders by artificial intelligence|The doctor takes pictures of the lower extremities and uploads them to the IVENUS application, which automatically determines the clinical class according to CEAP. Further, the doctor independently determines the clinical class according to CEAP and enters the data into the register.|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Determination of the sensitivity and specificity | Determination of the sensitivity and specificity of the method for determining the clinical class of chronic venous diseases according to the CEAP classification using the IVENUS application (within C0-C2 classes). | 1 day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of participants with complications | Any serious adverse event will be recorded | 1 day |
Balloon Assisted Maceration Versus Rotational Thrombectomy in Dialysis Access Salvage

Study Overview
=================
Brief Summary
-----------------
The purpose of this research study is to compare how well a wire like device disrupts and removes blood clot in your blocked dialysis graft/fistula in comparison to inflating a balloon in your access for the same purpose. The wire like device is called the Cleaner XT and has already been approved by the government/Food and Drug Administration (FDA) for this purpose. Blood clots in your dialysis access can be fairly common and prevent you from being able to get dialysis. Procedures for opening this blockage must then be performed which is why you have been sent to the hospital today. There are different ways of opening up this blockage which can including blowing up a balloon in multiple areas of the graft/fistula to squeeze the blood clot to break up the blockage or using a wire like device to break up the clot in small pieces and try to remove all of the clot from the wall of the graft/fistula.

Official Title
-----------------
Pharmacomechanical Dialysis Access Salvage With Balloon Assisted Maceration Versus Rotational Thrombectomy

Conditions
-----------------
Dialysis; Complications, Dialysis Access Malfunction

Intervention / Treatment
-----------------
* Device: Cleaner XT
* Device: Balloon


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: End stage renal disease on hemodialysis Age greater than 18 Upper extremity dialysis graft/fistula Exclusion Criteria: Pregnant Incarcerated Age under 18 Inability to consent for self Graft/fistula in a location other than upper extremity Peritoneal dialysis Catheter dialysis

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Rotational Thrombectomy<br>Use of the Cleaner XT | Device: Cleaner XT<br>* Wire like device that rotates to allow for wall to wall disruption of thrombus.<br>|
| Active Comparator: Balloon Assisted maceration<br>Use of angioplasty balloons for balloon maceration | Device: Balloon<br>* Use of balloon for disrupting thrombus.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Secondary patency | How long the dialysis access remains functional after the procedure. | 6 months post procedurally | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Thrombosis of dialysis access
The Effect of Bone Mineral Density in Patients With Adult Cystic Fibrosis

Study Overview
=================
Brief Summary
-----------------
The study was conducted in the age range of 18-45 December, who were diagnosed with Cystic fibrosis.

Detailed Description
-----------------
60 voluntary patients who have signed the consent form will be included. Within the scope of the research the demographic information of the individuals will be recorded. Functional capacities of individuals With the Shuttle Walking Test at Increasing Speed, respiratory functions respiratory function test, with measurements of respiratory November muscle strength and endurance, the level of dyspnea was Modified Medical Peripheral November muscle strength hand dynamometers with Research Council (mMRC) Dyspnea Scale posture assessment with the Corbin Posture Analysis Scale, trunk mobility with the Trunk Pelvis-Hip Angle Test, core stabilization with Sahrmann's Core Stability Test, individuals' perception of cosmetic deformity Walter Reed visual assessment questionnaires

Official Title
-----------------
Erişkin Kistik Fibrozisli Bireylerde Kemik Mineral Yoğunluğunun Postür, Solunum Fonksiyonları ve Fonksiyonel Egzersiz Kapasitesi Üzerine Etkisi

Conditions
-----------------
Cystic Fibrosis, Postural Defect, Pulmonary Disease, Physical Inactivity

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients aged between 18-45 who were diagnosed with Cystic Fibrosis Exclusion Criteria: In the last year, patients; who had a fracture in any part of the patient's body who had undergone spine surgery who had an orthopedic, neurological or metastatic history in addition to Cystic Fibrosis

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| low bone mineral density<br>bone mineral density according to t and z score. | |
| normal bone mineral density<br>bone mineral density according to t and z score. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Functional Exercise Capacity | Functional exercise capacity by incremental shuttle walk test in patients with adult Cystic Fibrosis | 1 day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Posture | posture by Corbin Posture Analysis Form in patients with adult Cystic Fibrosis | 1 day |
IL35 Level in Vitiligo

Study Overview
=================
Brief Summary
-----------------
The aim of this observational study is to evaluate the level of the IL-35 protein in tissue biopsy from patients with active & stable vitiligo.

Official Title
-----------------
Assessment of Tissue Levels of IL-35 in Active and Stable Vitiligo

Conditions
-----------------
IL35, Vitiligo

Intervention / Treatment
-----------------
* Diagnostic Test: IL 35 in tissue biopsy


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with active and stable vitiligo Exclusion Criteria: Pregnant and lactating women. Patients with associated autoimmune or other dermatological diseases e.g., Alopecia areata and lupus erythematous. Patients already on both topical and systemic treatment at the time of recruitment. Patients on Immunosuppressive drugs. Other hypopigmented diseases such as pityriasis alba, tinea versicolor, lichen sclerosis, post inflammatory hypopigmentation and leprosy as excluded by lack of accentuation by wood's light examination.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 60 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active vitiligo<br> | Diagnostic Test: IL 35 in tissue biopsy<br>* Elisa testing<br>|
| Stable vitiligo<br> | Diagnostic Test: IL 35 in tissue biopsy<br>* Elisa testing<br>|
| Normal controls<br> | Diagnostic Test: IL 35 in tissue biopsy<br>* Elisa testing<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| level of IL35 in tissue biopsy |  | 3 months |
Describing Treatment Outcomes and Responses in Lymphoma-associated Hemophagocytic Lymphohistiocytosis

Study Overview
=================
Brief Summary
-----------------
The purpose of the study is to describe Hemophagocytic lymphohistiocytosis (HLH) in patients with lymphoma to identify possible therapeutic strategies to improve overall survival of the patients with lymphoma associated hemophagocytic lymphohistiocytosis.

Detailed Description
-----------------
Retrospective, multi-institutional study focused on describing the clinical features, laboratory parameters, treatments, and outcomes among individuals presenting with HLH in the setting of a lymphoma

Official Title
-----------------
Describing Treatment Outcomes and Responses in Lymphoma-associated Hemophagocytic Lymphohistiocytosis

Conditions
-----------------
Lymphoma, Hemophagocytic Lymphohistiocytoses

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with lymphoma that are fulfilling at least one of the following: A. Meeting 5 of 8 HLH-2004 diagnostic criteria OR B. Are OHI index positive (sCD25>3,900 U/mL and ferritin>1,000 ng/mL) Exclusion Criteria: Patients developing HLH> 1 month after lymphoma diagnosis (for aggressive lymphomas) Patients with incomplete treatment and response documentation
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Hemophagocytic lymphohistiocytosis (HLH) Patients<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To determine the factors predicting 180 days overall survival of patients with cancer that are HLH-2004/OHI+ | The investigators will gather data on different treatments received, time to treatment, and other factors and determine which is associated with survival. | The participant's survival would be assessed at 180 days from the malignancy diagnosis |
Delayed Language Development in Children With Cleft Palate at Sohag University Hospital

Study Overview
=================
Brief Summary
-----------------
This is a retrospective study on children with cleft palate who came to the multidisciplinary cleft clinic at Sohag University Hospital from September 2017 to September 2023

Official Title
-----------------
Delayed Language Development in Children With Cleft Palate at Sohag University Hospital

Conditions
-----------------
Delayed Language in Cleft Palate

Intervention / Treatment
-----------------
* Other: Data collection


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: cleft palate children's Exclusion Criteria: cleft lip only

Ages Eligible for Study
-----------------
Minimum Age: 2 Years
Maximum Age: 8 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Data collection|Data collection|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Correlation analysis between IQ with degree of delayed language in children with cleft palate (CCP). |  | 6 years |
Peripartum Cesarean Hysterectomy for Placenta Percreta

Study Overview
=================
Brief Summary
-----------------
The aim of this study is to address the possible preoperative determinants of extrauterine diseases in cases of placenta previa percreta and to compare the operative and postoperative characteristics of cases with and without extrauterine disease.

Detailed Description
-----------------
This will be a retrospective study of the data of women who underwent cesarean hysterectomy on placenta previa percreta who were classified as Federation of Gynecology and Obstetrics (FIGO) grade 3. Women without extrauterine disease (FIGO grade 3a) will be compared to women with extrauterine disease (FIGO grades 3b and 3c)

Official Title
-----------------
Peripartum Cesarean Hysterectomy for Placenta Percreta: a Retrospective Analysis of Cases With and Without Extrauterine Disease

Conditions
-----------------
Placenta Accreta

Intervention / Treatment
-----------------
* Procedure: Cesarean hysterectomy


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Women who underwent cesarean hysterectomy on placenta previa percreta (FIGO grade 3). Exclusion Criteria: Medical conditions complicating pregnancy. Blood diseases or bleeding tendencies
Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No extrauterine disease group<br>Women having placenta previa percreta with no extrauterine disease (FIGO grade 3a) | Procedure: Cesarean hysterectomy<br>* Cesarean hysterectomy due to placenta previa percreta with no extrauterine disease (FIGO grade 3a) or with extrauterine disease (FIGO grades 3b and 3c)<br>|
| Extrauterine disease group<br>Women having placenta previa percreta with extrauterine disease (FIGO grades 3b and 3c) | Procedure: Cesarean hysterectomy<br>* Cesarean hysterectomy due to placenta previa percreta with no extrauterine disease (FIGO grade 3a) or with extrauterine disease (FIGO grades 3b and 3c)<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Estimated amount of intraoperative blood loss | Calculated amount of blood loss during the operation | From start to end of operation | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
PAS, Placenta previa, Placenta accreta, Cesarean hysterectomy
A Clinical Validation Study to Evaluate the Diagnostic Accuracy of a Cough-based Auxiliary Diagnosis Algorithm for COPD

Study Overview
=================
Brief Summary
-----------------
Cough is one of the most common symptoms in COPD patients, and its different characteristics in amplitude, frequency and waveform can be analyzed by intelligent algorithms for the auxiliary diagnosis of COPD. The current study is to conduct external clinical validation of COPD auxiliary diagnosis algorithm and lung function prediction algorithm, and preliminatively verify the performance of the algorithm, with the ultimate goal of developing a portable and rapid COPD auxiliary diagnosis and condition assessment tool that can be used at home.

Official Title
-----------------
A Clinical Validation Study to Evaluate the Diagnostic Accuracy of a Cough-based Auxiliary Diagnosis Algorithm for Chronic Obstructive Pulmonary Disease (COPD)

Conditions
-----------------
COPD, Cough, Algorithm

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients with stable COPD were recruited for this study. Inclusion criteria were age ≥40 years and a diagnosis of COPD Exclusion Criteria: Exclusion criteria were acute exacerbations of respiratory symptoms within the past 2 weeks or significant comorbid cardiovascular, neurological, musculoskeletal, immunological, or infectious diseases.

Ages Eligible for Study
-----------------
Minimum Age: 40 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| COPD<br> | |
| other respiratory disease without COPD<br> | |
| healthy people without respiratory disease<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Positive Agreement Rate (PPA) | Positive Agreement Rate (PPA) of auxiliary Diagnosis Algorithm for COPD | 12.30.2024 |