Effect of Preventive Education on Reducing Urinary Bisphenol-A Levels in Adolescents

Study Overview
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Brief Summary
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It is known that Bisphenol-A (BPA) is the endocrine disrupting chemical that is most exposed by oral intake in daily life. Critical life periods when the sensitivity to these substances is known to be maximum; prenatal, postnatal and adolescence periods. The aim of this study is to compare the effects of plastic-free nutrition program, interactive education and BPA exposure feedback on urinary Bisphenol-A levels in adolescents with high use of packaged products.

Detailed Description
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By simple random sampling, female adolescents (n=36) staying in a high school hostel will be the intervention group, female adolescents not staying in hostels (n=36) will be the first comparison group, and female adolescents from another high school (n=36) will be the second comparison group. Plastic-free nutrition program (plastic-free diet, peer mentoring, interactive education and BPA exposure feedback) will be applied to the intervention group. Interactive training and BPA exposure feedback will be given to comparison group one, while only BPA exposure feedback will be given to comparison group two. Before and after the interventions, urinary BPA levels, use of plastic packaged products and bad nutrition attitudes of the adolescents will be monitored.

Official Title
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A Comparison of the Effects of a Plastic-Free Nutrition Program, Interactive Education, and Exposure Feedback on Bisphenol-A Levels in Adolescents With Packaged Product High Usage

Conditions
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Adolescent Behavior, Bisphenol A, Urine

Intervention / Treatment
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* Behavioral: Plastic-free nutrition program
* Behavioral: Interactive education
* Behavioral: BPA exposure feedback


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Willingness to participate in the research Being in the 14-18 age group Being a female student High (61-80 points) or moderate-high (41-60 points) scores from the plastic packaged product use questionnaire (PAUKA) Having a smart mobile phone Absence of obesity, hypertension, diabetes mellitus, cardiovascular, asthma, thyroid and kidney dysfunction or disease Absence of any syndrome (Metabolic, Turner Rett and Down syndrome etc.) Absence of any medication used continuously Absence of any chronic disease reported by the physician in the student follow-up/examination report Exclusion Criteria: Leaving school and hostel Not giving a spot urine sample Not participating in the plastic-free diet program in the hostel for the last week. Desire to leave the study Participation in trainings <50% Diagnosis of disease (diabetes mellitus, kidney disease, gluten or lactose intolerance, etc.) in which dietary habits were changed during the study. Experiencing a mental or physical illness that will prevent the continuity of participation in the study.

Ages Eligible for Study
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Minimum Age: 14 Years
Maximum Age: 18 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Nonrandomised controlled trial
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: plastic-free nutrition program<br>Plastic-free nutrition program will include plastic-free diet, peer mentoring, interactive education and BPA exposure feedback. | Behavioral: Plastic-free nutrition program<br>* Applying the plastic-free diet as four meals (three main meals, one snack) in pension kitchen. Promoting of glass water bottle giving and daily use. Interactive education program: Slogan competition, school board preparation, short film shooting, school canteen visits and plastic-free nutrition day event with the adolescents for four weeks by the researcher. Peer education will doing by Adolescents with Packaged Product Low Usage Feedback about BPA levels in theirs urinary sample.<br>Behavioral: Interactive education<br>* Interactive education program: Slogan competition, school board preparation, short film shooting, school canteen visits and plastic-free nutrition day event with the adolescents for four weeks by the researcher. Peer education will doing by Adolescents with Packaged Product Low Usage Feedback about BPA levels in theirs urinary sample<br>Behavioral: BPA exposure feedback<br>* Feedback about BPA levels in theirs urinary sample<br>|
| Active Comparator: Interactive education group<br>This group will take peer mentoring, interactive education and BPA exposure feedback. | Behavioral: Interactive education<br>* Interactive education program: Slogan competition, school board preparation, short film shooting, school canteen visits and plastic-free nutrition day event with the adolescents for four weeks by the researcher. Peer education will doing by Adolescents with Packaged Product Low Usage Feedback about BPA levels in theirs urinary sample<br>Behavioral: BPA exposure feedback<br>* Feedback about BPA levels in theirs urinary sample<br>|
| Active Comparator: BPA feedback group<br>This group will take only BPA exposure feedback. | Behavioral: BPA exposure feedback<br>* Feedback about BPA levels in theirs urinary sample<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Urinary BPA level | Urinary Bisphenol A | Baseline-Second month | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Plastic Packaged Product Usage | 0-20 points indicate the use of low plastic packaged products, 21-40 points indicate the use of medium plastic packaged products, 41-60 points indicate the use of medium-high plastic packaged products, and 61-80 points indicate the use of high plastic packaged products. | Baseline-Second month | 
| Attitude Towards Healthy Eating | 11 points obtained from the scale are very low, 12-22 points low, 23-33 points medium, 34-44 points high, 45-55 points ideally high, indicating the attitude towards healthy and plastic-free nutrition. | Baseline-Second month | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Bisphenol A, urinary test, adolescent, Packaged Product Usage