Our Anesthesia Experiences in Hepatopancreatobiliary Surgery Practices: a Retrospective Study

Study Overview
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Brief Summary
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Has the evolving anesthetic management in major abdominal surgeries had a positive impact on patients' one-year postoperative mortality and length of hospital stay? Which of the anesthetic management parameters have influenced mortality and hospital stay duration in these patients? To address these questions, we have planned to retrospectively review patients who underwent surgery at our center.

Detailed Description
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In our study, we aimed to compile our practices over the last 5 years by evaluating the impact of perioperative and postoperative anesthetic management on morbidity and mortality in hepatopancreatobiliary surgical patients. Our primary outcome was to form a comprehensive understanding of our anesthesia experiences during the preoperative, perioperative, and postoperative periods in this patient group. Our secondary outcome was to assess the influence of preoperative and perioperative anesthetic management on the morbidity and mortality of these patients.

Official Title
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Our Anesthesia Experiences in Hepatopancreatobiliary Surgery Practices: a Retrospective Study

Conditions
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Experience, Life

Intervention / Treatment
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* Other: a retrospective study


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: The study will include data from patients who have undergone their first operation with the diagnoses of liver malignancy, cholangiocarcinoma, and pancreatic malignancy during the period from October 2017 to February 2022. Exclusion Criteria: Data from patients who were deemed inoperable during the perioperative period after being taken into surgery with their current diagnosis, as well as data from patients who underwent repeat operations, were excluded from the study for their second and subsequent hospitalizations.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| preoperative and perioperative anaesthetic management<br>We have planned to retrospectively review data for patients aged 18 and above who underwent major abdominal surgery at our center between October 2017 and February 2022. The study aims to record data regarding the administration of thromboprophylaxis, preoperative hemoglobin values, and Revised Cardiac Risk Index scores and their impact on one-year postoperative mortality. Additionally, we intend to examine the effects of the amount of fluid administered during the perioperative period, the application of epidural analgesia, and the use of blood products on hospital stay duration and one-year postoperative mortality. | Other: a retrospective study<br>* a retrospective study<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| form a comprehensive understanding of our anesthesia experiences during the preoperative, perioperative, and postoperative periods in this patient group |  | october2017-february2022 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| assess the influence of preoperative and perioperative anesthetic management on the morbidity and mortality of these patients. |  | october2017-february2022 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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major abdominal surgery, Revised Cardiac Risk Index, Epidural analgesia, perioperative fluid management, ERAS protocols