Nature-based Therapies in Stroke Rehabilitation

Study Overview
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Brief Summary
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Stroke rehabilitation patients are subjected to additional nature-based therapies during a rehabilitation ward period.

Detailed Description
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Inward stroke rehabilitation patients are selected randomly into two groups: intervention and control groups in proportions 1-2:1. Blood samples and microbiom samples of saliva, skin and feces are taken from all patients prior to interventions. These are controlled after 4 weeks from the beginning of the study and 3 months after signing-off the ward. Questionnaires eg on moods, life quality and function deficits are conducted in the beginning of the study, after 4 weeks from the start and 3 months after signing-off. Physiological measurements will be done to observe autonomic nerve status. The interventions consisting of therapy sessions in the hospital nearby nature will be conducted trice a week one of them being an individual nature-visit with the research worker, one in group and one with family-member or volunteer. The moods and quality of life of the family-member participating in the study will also be followed up. The control group is adviced to do simple, more conventional rehabilitative tasks indoors.

Official Title
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Nature-based Therapies Supporting Conventional Therapies in Promoting Stroke Rehabilitation: a Randomised Controlled Pilot Study.

Conditions
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Rehabilitation, Stroke

Intervention / Treatment
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* Procedure: Nature-based therapy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Acute/Subacute stroke, rehabilitation ward patient Exclusion Criteria: Incapable of independent decision making Traumatic bleeding in brain tissue Severe aphasia Severe, malign ongoing disease

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Randomised controlled study, intervention and control groups
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Nature-based therapy intervention group<br>Patients getting additional therapies outdoors | Procedure: Nature-based therapy<br>* Therapy sessions conducted outdoors<br>|
| No Intervention: Control group<br>Patients getting additional rehabitation tasks indoors | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| PROMIS | Functional deficits | 0-30 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| WHODAS | Eg life quality | 0-30 days | 
| GAS | Mental status | 0-120 days | 
| Therapeutic effects | Core-10 | 0-30 days | 
| Microbiom | Microbial analyses of stool, saliva and flakes of skin | 0-120 days | 
| Nerve system activity | A portable device measurement eg heart rate and activity | 0-30 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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rehabilitation, stroke, nature-based, therapy, microbiom, gut-brain axis