Effects of Postural Adjustment on Hemodynamics in Patients Undergoing Prone Spine Surgery Under General Anesthesia

Study Overview
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Brief Summary
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The prone position is a special position often used for spinal surgery. As a special position of general anesthesia, after induction of general anesthesia, severe hemodynamic fluctuations often occur when the supine position is changed to the prone position, which seriously affects the patient's circulatory and respiratory functions.

Official Title
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Effects of Postural Adjustment on Hemodynamics in Patients Undergoing Prone Spine Surgery Under General Anesthesia

Conditions
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Asana Adjustment

Intervention / Treatment
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* Behavioral: Asana adjustment


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Prone spine surgery after general anesthesia is planned. Age 18 85 years old. ASA grade I or II. BMI18.3-30kg/m2 Exclusion Criteria: Unstable angina or myocardial infarction, coronary heart disease, congestive heart failure, structural heart disease, arrhythmia within 6 months; Increased intracranial pressure and central nervous system injury or disease; Severe hypertension Patients with other diseases affecting their own circulatory system. Have or have a history of severe mental disorders; Bleeding volume >600ml or intraoperative blood transfusion treatment. Severe liver and kidney insufficiency

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Trendelenburg position<br> | Behavioral: Asana adjustment<br>* Adjust the operating table to 15° head height and foot low in advance. The patient is then slowly turned over from the transport table to the operating table and completed in the prone position. After the patient's hemodynamic stability is smooth, adjust the operating table to the level.<br>|
| No Intervention: Procumbent<br> | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Blood pressure | Hemodynamics | Preoperatively,5 minute after anesthesia induction,Immediately before the prone position, Immediately after the prone position,1 minute after prone position, 3 minute after prone position,10 minute after prone position,Half an hour after prone position | 
| Changes in the level of Cardiac output | Cardiac output | Preoperatively,5 minute after anesthesia induction,Immediately before the prone position, Immediately after the prone position,1 minute after prone position, 3 minute after prone position,10 minute after prone position,Half an hour after prone position | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Intra-abdominal pressure level | Intra-abdominal pressure | Preoperatively,5 minute after anesthesia induction,Immediately before the prone position, Immediately after the prone position,1 minute after prone position, 3 minute after prone position,10 minute after prone position,Half an hour after prone position | 
| Vasoactive drugs | Vasoactive drug dosage | Intraoperatively | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Trendelenburg position, Prone Position, Hemodynamics, Intra-abdominal pressure, Cardiac output