Matcha Green Tea Effects at Rest and During Moderate-intensity Exercise in Females

Study Overview
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Brief Summary
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Intake of the green tea catechin epigallocatechin (EGCG) increased fat oxidation during walking. It is also known to reduce blood pressure and improve body composition. This research will expand the insight on the effects by Matcha green tea supplementation and address the effects on heart rate variability, substrate oxidation at rest, and cardiovascular responses at rest in addition to metabolic and physiologic responses for a 1-hr walk in healthy females.

Detailed Description
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Intake of the catechin epigallocatechin (EGCG) increased fat oxidation during walking. It is also known to reduce blood pressure and improve body composition. EGCG is the most abundant and potent bioactive compound (50-80% of the total catechin content) found in Matcha green tea (MGT) and is usually consumed as a drink or in a capsulated from unfermented tea leaves. MGT polyphenols have antioxidant and anti-inflammatory properties, providing numerous health benefits, such as the reduced risk of type 2 diabetes and obesity. MGT supplementation (3g over a 24hr period) has been shown to enhance fat oxidation during 30-min brisk walking as well as lower respiratory exchange ratio in females. Understanding the effectiveness of the bioactive compounds found in natural food sources in improving human health is key to informing the general population and the public health policies preceding them; the daily consumption of drinks and food naturally high in EGCG content could be recommended as an essential part of a healthy lifestyle. This research will expand the insight on Matcha green tea supplementation address the effect on heart rate variability, substrate oxidation at rest, and cardiovascular responses at rest in addition to metabolic and physiologic responses for a 1-hr walk in healthy females.

Official Title
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Effects of Matcha Green Tea on Heart Rate Variability, Substrate Oxidation and Cardiovascular Response at Rest and During Moderate-intensity Exercise in Females

Conditions
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No Condition

Intervention / Treatment
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* Dietary Supplement: Matcha green tea
* Dietary Supplement: Placebo


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: healthy non-smokers not taking any supplements no known allergy to green tea Exclusion Criteria: smokers known high blood pressure on medication

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 30 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Crossover Assignment
Interventional Model Description: Randomized, placebo-controlled, crossover design
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Placebo<br>Participants will be supplemented with a placebo. | Dietary Supplement: Placebo<br>* This is the condition with the placebo<br>|
| Experimental: Matcha green tea<br>Participants will be supplemented with Matcha green tea. | Dietary Supplement: Matcha green tea<br>* This is the condition with the Matcha green tea<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Heart rate variability | Measurement of root mean square of standard deviation of RR intervals | Three weeks | 
| Carbohydrate oxidation | Measurement of carbohydrate oxidation in grams/minute | Three weeks | 
| Fat oxidation | Measurement of fat oxidation in grams/minute | Three weeks | 
| Cardiac output | Measurement of cardiac output in liters per minute | Three weeks | 
| Stroke volume | Measurement of stroke volume in milliliters | Three weeks | 
| Total peripheral resistance | Measurement of total peripheral resistance in (mmHg x min) / mL | Three weeks |