linjc16/ctgov huggingface dataset:
Facial Prediction Technology for Edentulous Patients

Study Overview
=================
Brief Summary
-----------------
According to data from the World Health Organization, approximately 160 million people worldwide are edentulous. The incidence increases with age, and the proportion of edentulous patients is higher in the population aged 60 and above. Loss of teeth or edentulism can affect facial appearance, causing people to feel self-conscious and loss confidence in social situations, and even lead to psychological illnesses. Therefore, edentulous patients not only pay close attention to the recovery of oral function but also attach great importance to facial contour improvement. For a long time, due to technological limitations, clinicians have been unable to depict the changes in facial contour after implant placement for patients before surgery. However, with the development of artificial intelligence technology, deep learning-based methods for predicting soft tissue facial deformation have made this mission a possibility. This study established a multi-modal dataset for edentulous patients before and after implant restoration to lay the foundation for predicting facial contour changes after implant treatment. A graph generative adversarial network based on multi-modal data was proposed to achieve fast and high-precision facial contour prediction. To address the common challenges of slow computation and excessive computational resource consumption in current triangular mesh deformation simulation methods, this project innovatively proposed a graph generative adversarial network that uses multi-modal data and incorporates self-attention mechanisms to achieve fast and high-precision facial contour prediction for edentulous patients after implant restoration.

Official Title
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Research on Facial Prediction Technology for Edentulous Implant-Supported Fixed Prostheses Based on Multimodal Data Fusion

Conditions
-----------------
Edentulous Jaw

Participation Criteria
=================
Eligibility Criteria
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Inclusion Criteria: Patients with complete edentulism, aged 50 years or above, in good physical health, Exclusion Criteria: patients who refuse to participate in the study， patients who cannot undergo facial scanning.

Ages Eligible for Study
-----------------
Minimum Age: 50 Years
Maximum Age: 100 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes in Soft Tissue Volume in the Lip Region after Implant Dentistry | Quantitative analysis of lip volume changes in patients after oral implant surgery using facial scanning equipment | Between pre-operation and after Implant-Supported Fixed Prostheses up to 3 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
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Edentulous Jaw, deep learning, oral implantology, facial prediction
Impact of COVID-19 on Sinus Augmentation Surgery

Study Overview
=================
Brief Summary
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The risk of Schneiderian membrane perforation and the postoperative complications of the sinus floor elevation surgery were evaluated for patients with and without history of COVID-19 infection.

Detailed Description
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COVID-19 induced chronic sinusitis with subsequent increased Schneiderian membrane thickness could increase the risk of its perforation during the sinus floor elevation. The aim of the study is to compare the incidence of Schneiderian membrane perforation and the postoperive complications of the sinus floor elevation in patients with and without history of COVID-19.

Official Title
-----------------
The Impact of COVID-19 on the Rate of Peri-operative Complications of Maxillary Sinus Floor Augmentation Procedure.

Conditions
-----------------
Bone Loss

Intervention / Treatment
-----------------
* Procedure: Sinus lift in patients with positive COVID-19 history
* Procedure: Sinus lift with negative COVID-19 history


Participation Criteria
=================
Eligibility Criteria
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Inclusion Criteria: 4 mm or less residual alveolar bone height Age more than 18 years Highly motivated patients Exclusion Criteria: Patients who suffer from any systemic disease sinus pathosis other than sinusitis induced covid 19 Patients under any medication that may interfere with the normal bone healing

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Sinus lift in patients with previous COVID-19 infection<br>Sinus floor augmentation in the posterior atrophic maxilla with delayed implant placement in patients with positive history of previous COVID-19 infection. | Procedure: Sinus lift in patients with positive COVID-19 history<br>* Sinus augmentation in the posterior atrophic maxilla in patients with positive COVID-19 history<br>|
| Active Comparator: Sinus lift in patients with negative history of previous COVID<br>Sinus floor augmentation in the posterior atrophic maxilla with delayed implant placement in patients with negative history of COVID-19 infection. | Procedure: Sinus lift with negative COVID-19 history<br>* Sinus augmentation in the posterior atrophic maxilla in patients with negative COVID-19 history<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Sinus membrane perforation | Intraoperative assessment of the incidence of sinus membrane perforation | Duration sinus lift |
Videos and Music for Reducing Anxiety and Pain During In-office Hysteroscopy

Study Overview
=================
Brief Summary
-----------------
The administration of pharmacological and non-pharmacological aids during in-office hysteroscopic surgery is often used to both relieve the patient from discomfort and facilitate the operator in performing the procedure. The investigators aim to test the hypothesis that watching a video clip or listening to music would act as non-pharmacological relief for reducing anxiety and pain during in-office hysteroscopy.

Official Title
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Usefulness of Videos and Music for Reducing Anxiety and Pain During In-office Hysteroscopy

Conditions
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Pain, Postoperative

Intervention / Treatment
-----------------
* Procedure: In-Office Hysteroscopy


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Premenopausal and postmenopausal women Indication for in-office operative hysteroscopy Exclusion Criteria: Denied consent Use of analgesic drugs before the procedure

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
Female

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Video<br> | Procedure: In-Office Hysteroscopy<br>* In-office hysteroscopic procedures were conducted using a 5mm continuous flow Office Hysteroscope using a vaginoscopic, no-touch, approach<br>|
| Music<br> | Procedure: In-Office Hysteroscopy<br>* In-office hysteroscopic procedures were conducted using a 5mm continuous flow Office Hysteroscope using a vaginoscopic, no-touch, approach<br>|
| Vocal-Local<br> | Procedure: In-Office Hysteroscopy<br>* In-office hysteroscopic procedures were conducted using a 5mm continuous flow Office Hysteroscope using a vaginoscopic, no-touch, approach<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The anxiety, evaluated by means of State-Trait Anxiety Inventory (STAI) questionaries | 20 (better) - 80 (worse) | 24 hours | 
| post-hysteroscopic pain, evaluated using a 1-10 Numeric Rating Scale (NRS) | 1 (better) - 10 (worse) | 24 hours |
Machine Learning Predictive Model for Rotator Cuff Repair Failure

Study Overview
=================
Brief Summary
-----------------
There is little overall evidence behind clinical practice guidelines for diagnosis and treatment of rotator cuff repair. The purpose of this study was to compare the performance of different machine learning models that use pre-operative data from an international and multicentric database to predict if a patient that underwent rotator cuff repair could achieve the minimal important change (MIC) for single assessment numeric evaluation (SANE) at one year follow-up.

Official Title
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Predictive Model for Minimal Important Change After Rotator Cuff Repair Using Machine Learning Methods: A Pilot Study

Conditions
-----------------
Rotator Cuff Tears

Intervention / Treatment
-----------------
* Procedure: Arthroscopic rotator cuff repair


Participation Criteria
=================
Eligibility Criteria
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Inclusion Criteria: Primarily treated for rotator cuff tears by partial or complete surgical repair with a planned arthroscopic procedure Reparable tears No language barrier hindering questionnaire completion or legal incompetence were not included Exclusion Criteria: missing pre- or post-operative single-assessment numeric evaluation (SANE)

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| MIC RCR patients<br>Patients who improved their SANE score beyond the minimal important change one year after arthroscopic rotator cuff repair | Procedure: Arthroscopic rotator cuff repair<br>* Patients underwent an arthroscopic repair for rotator cuff lesions<br>|
| No-MIC RCR patients<br>Patients who did not improve their SANE score beyond the minimal important change one year after arthroscopic rotator cuff repair | Procedure: Arthroscopic rotator cuff repair<br>* Patients underwent an arthroscopic repair for rotator cuff lesions<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| SANE score | Single Assessment Numeric Evaluation (SANE). From 0 (worst) to 100 (best). | At 12 post-operative months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Artificial intelligence, Machine Learning, Minimal Important Change
Early Clinical and Radiological Outcomes of Uncemented Fully Coated Stem With Patients of 85 Years and More, Complications and Risks Factor

Study Overview
=================
Brief Summary
-----------------
Retrospective, single-centre study. Review of patients aged 85 and over who underwent total hip replacement between June 2015 and February 2022. This is a femoral stem survival study with calculation of the complication rate in this population. The study does not focus on total hip replacements in the context of trauma. The secondary endpoint was the search for complication risk factors.

Official Title
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Early Clinical and Radiological Outcomes of Uncemented Fully Coated Stem With Patients of 85 Years and More, Complications and Risks Factor

Conditions
-----------------
Arthroplasty Complications

Intervention / Treatment
-----------------
* Procedure: Total hip arthroplasty


Participation Criteria
=================
Eligibility Criteria
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Inclusion Criteria: receive total hip arthroplasty with uncemented stem fully hydroxyapatites coated Exclusion Criteria: trauma context less than 3 month follow up Any surgery of the hip as medical history

Ages Eligible for Study
-----------------
Minimum Age: 85 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| patients 85 yearsold or orlder who hab total hip replacement with uncemented femoral stem<br> | Procedure: Total hip arthroplasty<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| rate of complication | survival study, any complications | minimum of 3 months follow up | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| risk factor of complications |  | minimum of 3 months follow up |
Orthopedic Oncology Surgery: Navigation, Intraoperative Imaging and Virtual Reality

Study Overview
=================
Brief Summary
-----------------
Noninterventional, prospective study of patients operated on for musculoskeletal neoplasms designed to evaluate the quality of surgical margins achievable with the use of navigated Intraoperative CT

Official Title
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Orthopedic Oncology Surgery: Navigation, Intraoperative Imaging and Virtual Reality

Conditions
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Neoplasms, Muscle Neoplasm

Intervention / Treatment
-----------------
* Diagnostic Test: evaluate the quality of surgical margins achievable with the use of navigated Intraoperative CT


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age: no limit Patients with musculoskeletal neoplasms predominantly in complex sites Patients who will have to undergo surgical resection/amputation for the management of their clinical case Preparation of preoperative planning discussed at DMT Surgery performed with the aid of Intraoperative CT Navigated Written informed consent Exclusion Criteria: - Inability to perform pre-post treatment assessment
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Popolation<br> | Diagnostic Test: evaluate the quality of surgical margins achievable with the use of navigated Intraoperative CT<br>* Noninterventional, prospective study of patients operated on for musculoskeletal neoplasms designed to evaluate the quality of surgical margins achievable with the use of navigated Intraoperative CT<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Quality of life | To evaluate the quality of the Surgical Margin in terms of the percentage of oncologically adequate resections, in patients with Musculoskeletal neoplasms undergoing navigated resection surgery with Intraoperative CT | Baseline |
Application Study of Infusing Irritant Medications Through Midline Catheter Based on Real World Study

Study Overview
=================
Brief Summary
-----------------
The goal of this observational study is to learn about the effect on midline catheter outcomes when infusing irritant medications through midline catheter. The main questions it aims to answer are:Identify the current situation of infusing irritant medications through midline catheter;Explore the effect on midline catheter outcomes when infusing irritant medications through midline catheter;Identify specific medications that affect catheter outcomes.

Detailed Description
-----------------
First, the patients were divided into two groups according to whether irritant medications were infused or not,then observed the rate of complications between the two groups.Second, grouped according to the irritant medications, Identify specific medications that affect catheter outcomes through statistical analysis.

Official Title
-----------------
Application Study of Infusing Irritant Medications Through Midline Catheter Based on Real World Study

Conditions
-----------------
Catheter Complications

Participation Criteria
=================
Eligibility Criteria
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Inclusion Criteria: Age ≥14 years old Patients who had a midline catheter Exclusion Criteria: Patients who received vesicant medications through the midline catheter Patients who had both a midline catheter and a central vascular access device

Ages Eligible for Study
-----------------
Minimum Age: 14 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| irritant medications group<br>Patients who used midline catheter to infuse irritant medications. | |
| nonirritant medications group<br>Patients who used midline catheter to infuse nonirritant medications. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| catheter complications | catheter complications rate | during catheter indwelling |
Persistence of Hepatitis A Antibody in Healthy Adults  32 Years Post Vaccination.

Study Overview
=================
Brief Summary
-----------------
The goal of this clinical trial is to evaluate the persistence of Hepatitis A antibody  32 years post vaccination in healthy adults. The questions this study will answer are: 1) how long antibody persists and 2) The immune response to an additional dose of vaccine among those with no detectable antibody. Participants will be asked to provide a blood specimen. Those with no detectable antibody will be offered an additional dose of vaccine. The kinetics of antibody response in this population will be summarized.

Official Title
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Open Label Study to Assess the  32-Year Persistence of Hepatitis A Antibody Among Participants in the Pivotal, Double-Blind, Placebo-Controlled Efficacy Study of VAQTA (Study 023-001)

Conditions
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Hepatitis A

Intervention / Treatment
-----------------
* Biological: Hepatitis A Vaccine


Participation Criteria
=================
Eligibility Criteria
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Inclusion Criteria: Consent obtained Participated in original hepatitis A study in 1991 No detectable hepatitis A antibody  32 years after study start Exclusion Criteria: Receipt of any dose of hepatitis A vaccine other than the hepatitis A vaccine used in the initial studies History of hepatitis A Receipt of blood transfusion or blood products, including immunoglobulins, within the past 6 months. Receipt of any vaccine within the 14 days before receipt of the additional dose of hepatitis A vaccine or scheduled to receive any vaccine within 30 days after receipt of a booster dose of vaccine.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Basic Science
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Revaccinated at 32 Years<br> | Biological: Hepatitis A Vaccine<br>* Hepatitis A Vaccine<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Persistence of Antibody | Hepatitis A antibody | 32 Years |
Health Status of Patients After Surgically Implanted Biological and TAVI: a Population-based Retrospective Analysis

Study Overview
=================
Brief Summary
-----------------
The overall project aim is to study outcomes following aortic valve replacement with surgically implanted bioprostheses or TAVI by retrieving data from the main social security carriers in Austria for the years 2010-2020.

Official Title
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Health Status of Patients After Surgically Implanted Biological and TAVI: a Population-based Retrospective Analysis

Conditions
-----------------
Aortic Valve Disease

Intervention / Treatment
-----------------
* Device: Aortic Valve Replacement


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: isolated aortic valve replacement in Austria (surgically implanted bioprostheses or TAVI) Exclusion Criteria: below 65 years of age coronary revascularization within 4 months before the index procedure concomitant heart surgery

Ages Eligible for Study
-----------------
Minimum Age: 65 Years
Maximum Age: 99 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Aortic valve replacement with surgically implanted bioprostheses<br> | Device: Aortic Valve Replacement<br>* Aortic Valve Replacement (surgically or TAVI)<br>|
| Aortic valve replacement with TAVI<br> | Device: Aortic Valve Replacement<br>* Aortic Valve Replacement (surgically or TAVI)<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| all-cause mortality | all cause mortality after aortic valve replacement | 10 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| reoperation | incidence of reoperation after aortic valve replacement | 10 years | 
| myocardial infaction | incidence of myocardial infaction after aortic valve replacement | 10 years | 
| heart failure | incidence of heart failure after aortic valve replacement | 10 years | 
| stroke | incidence of stroke after aortic valve replacement | 10 years |