Safety and Efficacy of the Minimally Invasive Bentall Procedure Via a Small Right Intercostal Incision in Patients With Aortic Root Lesions

Study Overview
=================
Brief Summary
-----------------
This study intends to include patients who had aortic root lesions and were treated with Bentall surgery from January 2019 to July 2023 in the First Affiliated Hospital of Xi'an Jiaotong University. The patients will be divided into the minimally invasive group and control group according to the surgical methods: the former underwent minimally invasive Bentall surgery through a small right intercostal incision; the latter underwent traditional Bentall surgery through a median sternal incision. By comparing the clinical data of patients in two groups, we will investigate the effect and safety of minimally invasive Bentall surgery.

Official Title
-----------------
Safety and Efficacy of the Minimally Invasive Bentall Procedure Via a Small Right Intercostal Incision in Patients With Aortic Root Lesions: an Investigator-initiated, Single-center, Retrospective Cohort Study

Conditions
-----------------
Aortic Dissection, Aortic Root Aneurysm, Minimally Invasive Surgical Procedures

Intervention / Treatment
-----------------
* Procedure: Minimally invasive Bentall procedure


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: - Patients who were diagnosed with aortic root lesions and treated with the Bentall procedure at the First Affiliated Hospital of Xi'an Jiaotong University from January 2019 to July 2023 will be included in this study. Exclusion Criteria: Previous sternotomy or aortic root surgery; Combined coronary artery disease requiring simultaneous coronary revascularization; Combined aortic arch lesions requiring simultaneous aortic arch surgery; Preoperative comorbidities with severe single or multiple organ failure; Incomplete clinical information;
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Minimally invasive Group<br>Patients who underwent minimally invasive Bentall procedure will be included. The minimally invasive Bentall procedure is performed through a small incision in the right intercostal space. | Procedure: Minimally invasive Bentall procedure<br>* The minimally invasive Bentall procedure is performed through a small incision in the right intercostal space.<br>|
| Control Group<br>Patient who underwent Bentall procedure through median sternotomy will be included. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 30-day mortality rate | It focuses on the mortality rate of all patients after the operation after 30 days. The data will be obtained from medical records. | 1-month after the opeation. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mortality rate during hospitalization | It focuses on the mortality rate of all patients after the operation during hospitalization. The data will be obtained from medical records. | About 10 days after the opeation. | 
| Blood transfusion volume during hospitalization | It focuses on the blood transfusion volumes of all patients after the operation during hospitalization. The data will be obtained from medical records. | About 10 days after the opeation. | 
| Postoperative ICU length of stay | It focuses on the ICU length of stay of all patients after the operation. The data will be obtained from medical records. | About 3 days after the opeation. | 
| Postoperative ventilation time | It focuses on the postoperative ventilation time of all patients after the operation. The data will be obtained from medical records. | About 1 day after the operation. |