Omitting Drains After Repair of Peptic Ulcer Perforations

Study Overview
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Brief Summary
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. This study aimed to evaluate ERAS application outcomes via omitting the intraabdominal drains compared to regular using of the drains in patients undergoing perforated duodenal ulcer repairs in emergency abdominal surgeries.

Detailed Description
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Patients will be randomly assigned into two groups. In Group A : the investigators will put intraabdominal drains, and in Group ,thd investigators will not put any intraabdominal drains. Our primary outcomes will be hospital stayl engthand pain score;Data analysis packages will be SPSS version 21 Qualitative data will be presented by number and percentage, quantitative data by mean, standard deviation, median and interquartile range.

Official Title
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Omitting of Usage of Intraabdominal Drains After Repair of Peptic Ulcer Perforations Compared to Traditional Use of Drains; Comparative Study

Conditions
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Peptic Ulcer Perforations

Intervention / Treatment
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* Other: Omitting of usage of intraabdominal drains after repair of peptic ulcer perforations
* Other: Using intraabdominal drains


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: - Patients older than 18 years with perforated peptic ulcer who underwent exploratory laparotomy or laparoscopy and repair with omental pedicle techniques will included in the study. Exclusion Criteria: preoperative shock on admission. Delayed presentation more than 24 hours. known malignant gastric ulcers confirmed by histopathology. the presence of neuropsychiatric disease, pregnant and lactating women. predisposing factors for impaired wound healing (e.g., currently using immunosuppressive agents, or chronic use of steroids), the presence of HIV/AIDS. Intraoperative findings consistent with malignant ulcers. • American Society of Anesthesiologists grade III/IV, or had an alternative perioperative diagnosis. • Ulcer size more than 2 cm in diameter.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Randomized controlled trial
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Drain group<br>In Group A the investigators will put intraabdominal drains | Other: Using intraabdominal drains<br>* The investigators will put intraabdominal drains<br>|
| Experimental: No drain group<br>The investigators will not put any intraabdominal drains | Other: Omitting of usage of intraabdominal drains after repair of peptic ulcer perforations<br>* omitting the intraabdominal drains<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| number of days of hospital stay | hospital stay length | Up to 30 days | 
| number of patients with infection-related postoperative complications such as superficial, deep or organ space SSI, hospital acquired pneumonia | number of patients with infection-related postoperative complications such as superficial, deep or organ space SSI, hospital acquired pneumonia | 30 days | 
| incidence of Post operative repair leak | incidence of Post operative repair leak | 30 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| number of days before frist bowel motion | number of days before frist bowel motion | 7 days | 
| severity of operative pain measured by Visual Analogue Scale (VAS | from 1 to 10 1 indicated minimum pain and 10 maximum pain | 7 days | 
| INCIDENCE OF postoperative nausea and vomiting (PONAV | INCIDENCE OF postoperative nausea and vomiting (PONAV | 7 days |