Relevance and Efficiency of SecOnd Line Workup for Uveitis

Study Overview
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Brief Summary
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The first-line etiological workup is currently poorly codified, and some patients undergo sequential investigations. However, the reason which lead the clinician to perform subsequent exams, and the relevance of such exams, remain to be determined. The main objective of the study was to assess the relevance of a second-line workup of patients with uveitis.

Detailed Description
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The first-line etiological workup is currently poorly codified, with some patients undergoing extensive investigations, and other minimal etiological workup. In addition, some patients undergo sequential investigations. However, the reason which lead the clinician to perform subsequent exams, and the relevance of investigations performed after a first line workup remain to be determined. The main objective of the study was to assess the relevance of a second-line workup of patients with uveitis.Secondary objectives were to describe the reasons of these second-line workups, and to determine which exams were the most relevant, and the determinants of its realization.

Official Title
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Relevance and Efficiency of SecOnd Line Workup for Uveitis

Conditions
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Uveitis

Intervention / Treatment
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* Other: second line investigations for uveitis etiological workup


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: adult patient at least one etiological workup in our center Exclusion Criteria: only episode of acute anterior uveitis quickly responding to topical treatments diagnostic ophthalmologically obvious opposition to collection of data

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients with only one etiological workup<br>patients who underwent only one set of exams for etiological investigations of uveitis | Other: second line investigations for uveitis etiological workup<br>* Biological, radiological or histological investigations performed after a first line etiological workup. Investigations conducted following abnormal resultats of first line exams were not considered as second line exams (e.g. : bronchoscopy performed after abrnomal CT scan).<br>|
| Patients without diagnostic modification subsequently to the second etiological workup<br>Patients who underwent a second etiological workup, independently of the results of the fist line investigations, and whose diagnosis was not modified by the second line investigations. | Other: second line investigations for uveitis etiological workup<br>* Biological, radiological or histological investigations performed after a first line etiological workup. Investigations conducted following abnormal resultats of first line exams were not considered as second line exams (e.g. : bronchoscopy performed after abrnomal CT scan).<br>|
| Patients with diagnostic modification subsequently to the second etiological workup<br>Patients who underwent a second etiological workup, independently of the results of the fist line investigations, and whose diagnosis was modified by the second line investigations. | Other: second line investigations for uveitis etiological workup<br>* Biological, radiological or histological investigations performed after a first line etiological workup. Investigations conducted following abnormal resultats of first line exams were not considered as second line exams (e.g. : bronchoscopy performed after abrnomal CT scan).<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| patients undergoing a second line etiological workup | percentage of patients undergoing a second line etiological workup | through study completion, an average of 18 months |