linjc16/ctgov huggingface dataset:
Melatonin and Its Effect on the Perioperative Opioid Needs in Pediatric Patients Undergoing Laparoscopic Surgery.

Study Overview
=================
Brief Summary
-----------------
To study the role of Preoperative Melatonin adminsteration in pediatric patients undergoing laparoscopic surgeries regarding its analgesic and sedative effects

Official Title
-----------------
Melatonin and Its Effect on the Perioperative Opioid Needs in Pediatric Patients Undergoing Laparoscopic Surgery.

Conditions
-----------------
Postoperative Pain

Intervention / Treatment
-----------------
* Drug: Melatonin 3 MG
* Other: Placebo


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age from 2 to 10 years. Sex: Both sexes. Patients with ASA classificaion I and II. Exclusion Criteria: Declining to give written informed consent. History of allergy to the medications used in the study. psychiatric disorder. ASA classification III-V. Fever ,cough , asthma or upper respiratory tract infection, neuromuscular disorders, spine abnormalities. Anticipated difficult airway . History of malignant hyperthermia

Ages Eligible for Study
-----------------
Minimum Age: 2 Years
Maximum Age: 10 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Group A<br>patients undergoing abdominal surgery receiving melatonin | Drug: Melatonin 3 MG<br>* Preopertive melatonin adminstration oral 0.2 mg /kg 45 min before general anaethesia.<br>|
| Placebo Comparator: Group B<br>control group | Other: Placebo<br>* Placebo medication will be given to control group<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative pain | Assesment of pain will be done using Face, Leg, Activity , Crying and Consolability behavioural pain scale (FLACC), Each category is scored on the 0-2 scale, which results in a total score of 0-10. 0 = Relaxed and comfortable, 1-3 = Mild discomfort, 4-6 = Moderate pain and 7-10 = Severe discomfort or pain or both. | Discharge from postanesthesia care unit (1 hour) |
Characteristics of Trachomatous Corneal Opacity in Fayoum University Hospital

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to assess the characteristics of trachomatous corneal opacity in patients with signs of trachoma using Anterior segment Optic coherence tomography and Pentacam

Detailed Description
-----------------
After approval of the local institutional ethics committee and local institutional review board, patient presented to Fayoum University Hospital was examined for corneal opacity with signs of trachoma after a detailed informed consent was signed by eligible patients and investigated by Anterior Segment Optic coherence Tomography and Pentacam. Descriptive statistics were presented in the form of mean and standard deviation for numerical variables while numbers and percentages are used for the categorical variables. Paired samples t-test was used to study anterior segment Optic Coherence tomography and pentacam in evaluating corneal thickness. Bland-Altman plot was used to study the agreement between the two methods IBM SPSS version 28 for Windows software was used for the analysis and Stata 16 was used for the Bland-Altman plot. A p-value of < 0.05 was considered significant.

Official Title
-----------------
Characteristics of Trachomatous Corneal Opacity in Fayoum University Hospital

Conditions
-----------------
Corneal Opacity

Intervention / Treatment
-----------------
* Diagnostic Test: Corneal topography


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients with corneal opacity accompanied by signs of trachoma Exclusion Criteria: corneal opacity due other causes history of corneal surgery
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: Corneal topography|AS-OCT,PENTACAM|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Corneal imaging | AS-OCT and PENTACAM in patients with trachomatous corneal opacity | we will recruit patients who meer the inclusion criteria during the study period february-August 2022 |
Pain Clinic Provides Public Health Safety

Study Overview
=================
Brief Summary
-----------------
Chronic pain is associated with psychological disorders; which may affect a patient's socioeconomic, legal, domestic, and employment situations. This prospective observational study evaluates the impact of pain management on patients' health, social, economic, and employment status. It explores the impact of pain clinic services on patients' mental health, family health, public health, road safety, addiction situation, public safety, injury rehabilitation and employment situation.

Detailed Description
-----------------
Chronic pain is associated with many behavioral or psychological disorders. The psychological disorders may have negative impact on the patient's social, economic, health, legal, domestic, relationship and employment situations. This prospective observational study evaluates the impact of pain management services on the patients' health, social, economic, and employment status. The clinical study explores the impact of pain clinic services on patients' mental health, childcare, family health, public health, road safety, addiction situation, public safety, injury rehabilitation, employment status and housing situation.

Official Title
-----------------
Pain Clinic Provides Public Health and Safety Services

Conditions
-----------------
Social Functioning, Addiction, Substance, Safety Issues, Road Injury, Patient Compliance, Chronic Pain

Intervention / Treatment
-----------------
* Behavioral: Behavioral therapy


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: adult chronic pain patients patients with psychosocial problems Exclusion Criteria: pediatric patients patients with severe cognitive dysfunction

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 99 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Adult chronic pain patients<br>Adult chronic pain patients who received pain management and/or addiction therapy | Behavioral: Behavioral therapy<br>* Behavioral and supportive therapy<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Percentage of patients who had psychosocial problems | Percentage of patients who had psychosocial problems | 12 months |
Clinical Comparison of Patients With Transthyretin Cardiac Amyloidosis and Patients With Heart Failure With Reduced Ejection Fraction

Study Overview
=================
Brief Summary
-----------------
Clinical comparison of patients with transthyretin cardiac amyloidosis and patients with heart failure with reduced ejection fraction

Official Title
-----------------
Clinical Comparison of Patients With Transthyretin Cardiac Amyloidosis and Patients With Heart Failure With Reduced Ejection Fraction

Conditions
-----------------
Transthyretin Amyloid Cardiomyopathy, Heart Failure

Intervention / Treatment
-----------------
* Diagnostic Test: Echocardiography


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age >65 ATTRwt diagnosis for patients, either with DPD-scintigraphy or myocardiac biopsy informed consent Exclusion Criteria: Alder <65 No ATTRwt diagnosis

Ages Eligible for Study
-----------------
Minimum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Screening
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Echocardiography<br> | Diagnostic Test: Echocardiography<br>* Echocardiography<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| intraventricular wall thickness | echocardiographic measurement | 1 year | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Heart Failure, Echocardiography
OCT and OCT-A Afer Diabetic Vitrectomy in PDR

Study Overview
=================
Brief Summary
-----------------
Detection of any structural or vascular changes at the macula after Pars Plana Vitrectomy ( PPV ) in cases with complicated proliferative diabetic retinopathy ( PDR )

Official Title
-----------------
OCT and OCT Angiography After Diabetic Vitrectomy With or Without Internal Limiting Membrane Peeling for Patients With PDR

Conditions
-----------------
Proliferative Diabetic Retinopathy

Intervention / Treatment
-----------------
* Diagnostic Test: OCT and OCT-A


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Cases with complicated PDR as persistant vitreous hemorrhage or tractional retinal detachment involving or threatening the macula underwent PPV with or without ILM peeling Exclusion Criteria: eyes with media opacity after PPV not allowing imaging of the macula
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: OCT and OCT-A|OCT and OCT angiography for the macula|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| OCT and OCT angiography to assess the macular thickness , outline and vascularity | Detection of any structural or vascular changes at the macula after Pars Plana Vitrectomy ( PPV ) in cases with complicated proliferative diabetic retinopathy ( PDR ) . | 3 months after surgery |
My Meal Plate - Promoting the Health Literacy of Patients

Study Overview
=================
Brief Summary
-----------------
This study was to investigate the results on health literacy through the program of my meal plate.

Detailed Description
-----------------
Subjects were randomized to the intervention group and control group. The primary outcome was the Health Literacy on my Plate.

Official Title
-----------------
My Meal Plate - Promoting the Health Literacy of Patients

Conditions
-----------------
Nutrition, Healthy

Intervention / Treatment
-----------------
* Other: Health literacy program


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients who have ordered the general diet of the hospital and took more than three meals in a row. Exclusion Criteria: pregnant woman unconscious people who cannot read

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 99 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Health Services Research
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Health literacy group<br>Participants received the health literacy related to healthy plate. | Other: Health literacy program<br>* Health literacy program was the health education related to healthy plate.<br>|
| No Intervention: Control group<br>Participants did not receive the health literacy related to healthy plate. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Health Eating Literacy questionnaire | The Health Eating Literacy questionnaire is to assess person's ability to understand and remember on the healthcare information related to healthy eating principles. | 30 minutes | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
health literacy
Heart Rate Variability and Nocturnal Blood Oxygen Saturation in Patients With Idiopathic Pulmonary Fibrosis

Study Overview
=================
Brief Summary
-----------------
The goal of this observational study is to compare the overnight heart rate variability (HRV) and nocturnal oxygen saturation (SpO2) in patients with idiopathic pulmonary fibrosis (IPF). The main questions it aims to answer are: (1). if there are correlations between pulmonary function test and HRV and overnight SpO2; (2). if HRV and SpO2 can predict the occurrence of acute exacerbation in patients with IPF. Participants will be asked to examine pulmonary function test (including lung volumes and six-minute walk test) and wear pulse oxygenation recorder and LARGAN ECG Holter (LARGAN HEALTH TECHNOLOGY Sleep Apnea And Sleep Quality Examination System) during sleep.

Official Title
-----------------
Differences in Heart Rate Variability and Nocturnal Blood Oxygen Saturation of Patients With Idiopathic Pulmonary Fibrosis Between at Baseline and During Acute Exacerbation

Conditions
-----------------
Idiopathic Pulmonary Fibrosis

Intervention / Treatment
-----------------
* Device: LARGAN ECG Holter


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: individuals meet the diagnosis of idiopathic pulmonary fibrosis individuals agree to participate this study and sign the informed consent individuals have cognitive and behavioral abilities Exclusion Criteria: age less than 50 years old individuals refuse to participate this study and sign the informed consent individuals of unclear consciousness

Ages Eligible for Study
-----------------
Minimum Age: 50 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| IPF patients with acute exacerbation during test period<br>IPF patients completing pulmonary function, overnight SpO2 monitor and LARGAN ECG Holter reqire hospitalization during test period. | Device: LARGAN ECG Holter<br>* wear LARGAN ECG Holter during sleep once after completion of pulmonary function test<br>|
| IPF patients without acute exacerbation during test period<br>IPF patients completing pulmonary function, overnight SpO2 monitor and LARGAN ECG Holter remain stable during test period. | Device: LARGAN ECG Holter<br>* wear LARGAN ECG Holter during sleep once after completion of pulmonary function test<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The correlations between measures of pulmonary function test and heart rate variability |  | 1 day test duration |
Evaluation of Muscle Involvement in Systemic Sclerosis

Study Overview
=================
Brief Summary
-----------------
Muscle involvement is poorly described in patients with systemic sclerosis (SSc) . The prevalence of muscle damage is evaluated at 5-95 % of SSc patients, particularly due to variable definitions depending on the series in the scientific litterature. Muscle clinicobiological and histological presentation an response to immunosuppressive treatments are highly variable. Muscle involvement defined by creatinine kinase (CK) elevation, the presence of electromyography (EMG) abnormalities and/or muscle magnetic resonance imaging (MRI) hyperintensities and/or muscle biopsy inflammation appears to be associated with diffuse SSc, the presence of cardiac damage, and anti-PM-Scl antibodies. The main objective is to describe muscular manifestations associated with SSc. Secondary objectives are: to compare characteristics between SSc patients with and without muscle involvement to determine homogeneous groups of SSc patients with muscle involvement

Official Title
-----------------
Evaluation of Muscle Involvement in Systemic Sclerosis

Conditions
-----------------
Systemic Sclerosis

Intervention / Treatment
-----------------
* Other: muscle involvement


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with systemic sclerosis according to 2013 ACR/EULAR classification criteria

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| SSc patients<br> | Other: muscle involvement<br>* evaluation of muscle involvement<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of patients with muscle involvement | Muscle involvement is defined by persistent CK elevation, and/or muscle MRI hyperintensities, and/or myogenic abnormalities on EMG, and/or presence of inflammatory myopathy on muscle biopsy | baseline (J0) |
Effects of Smartphone-Based Stress Reduction Training on Social Relations

Study Overview
=================
Brief Summary
-----------------
The purpose of this research study is to find out how two different online stress reduction training programs affect people's daily experiences and social relations. The researchers think that people's thoughts, emotions, and behavior toward others may be influenced by stress reduction programs. This study will allow them to study the effectiveness of stress reduction programs for important real-world psychological outcomes.

Official Title
-----------------
Effects of Smartphone-Based Stress Reduction Training on Social Relations

Conditions
-----------------
Emotions

Intervention / Treatment
-----------------
* Behavioral: Stress reduction program 1
* Behavioral: Stress reduction program 2


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Virginia Commonwealth University students age 18 years or older Healthy English literate non-immigrant not practicing stress reduction techniques for more than 60 minutes a week ownership of a smartphone Exclusion Criteria: People who are not Virginia Commonwealth University students major, uncorrected sensory impairments and cognitive deficits psychiatric disorders or history thereof new diagnosis of a (non-acute) medical or psychiatric condition within the last 3 months current drug abuse

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Stress reduction program 1<br>Participants will complete stress reduction lessons for two weeks | Behavioral: Stress reduction program 1<br>* Participants will receive daily online lessons<br>|
| Experimental: Stress reduction program 2<br>Participants will complete stress reduction lessons for two weeks | Behavioral: Stress reduction program 2<br>* Participants will receive daily online lessons<br>|
| No Intervention: Waitlist<br>Participants will have an opportunity to complete one of the two programs of stress reduction lessons after data collection is completed | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in state emotion regulation | Participants will complete a state emotion strategies measure which will ask them to check various actions they are taking to change their thoughts and feelings. Change in total number of actions checked will be calculated. | Baseline to post intervention, approximately 2 weeks |