Sticker Pad Containing Essential Oil in Volunteer With High Blood Pressure

Study Overview
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Brief Summary
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The aims of the study were to evaluate efficacy and safety of the sticker pads containing lavender and ylang ylang oil in high blood pressure volunteers

Detailed Description
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High blood pressure volunteers were divided into the sticker group or the placebo group. The volunteers attached the pad to their shirt for 3, 7, 10, and 14 days. Blood pressure, pulse rate, adverse reactions, and satisfaction were investigated.

Official Title
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Efficacy and Safety of Sticker Pad Containing Essential Oil in Volunteer With High Blood Pressure

Conditions
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High Blood Pressure

Intervention / Treatment
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* Device: Sticker pads containing lavender and ylang ylang oil
* Device: Placebo


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: age more than 18 years systolic blood pressure of more than 130 mmHg but less than 160 mmHg or diastolic blood pressure more than 80 mmHg but less than 100 mmHg no hypertensive medicine no dermatological diseases, immunocompromised diseases, seizures, asthma, or respiratory diseases Exclusion Criteria: an unstable condition of other diseases olfactory problems pregnancy lactation

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Sticker pads containing lavender and ylang ylang oil<br>The subjects in the sticker pad group attached an sticker pad (0.3% lavender oil and 0.7% ylang ylang oil) to their shirt, close to the right side of the neck, for 14 days | Device: Sticker pads containing lavender and ylang ylang oil<br>* The sticker pad group attached an sticker pad (0.3% lavender oil and 0.7% ylang ylang oil) to their shirt, close to the right side of the neck, for 14 days,<br>|
| Placebo Comparator: Placebo group<br>The placebo group attached a sticker pad without lavender and ylang ylang oil to their shirt, close to the right side of the neck, for 14 days. | Device: Placebo<br>* The placebo group attached a sticker pad without lavender and ylang ylang oil to their shirt, close to the right side of the neck, for 14 days.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Systolic blood pressure | Measure systolic blood pressure in mmHg | 14 days | 
| Diastolic blood pressure | Measure diastolic blood pressure in mmHg | 14 days | 
| Pulse rate | Measure pulse rate in beats/minutes | 14 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| adverse reactions of the respiratory tract, skin, gastrointestinal tract, eye, and central nervous system | Using a score of 0 to 3, following an increase of severity | 14 days | 
| Satisfaction of the product | Using a visual analogue scale, 0 means not satisfied, 10 means very satisfied | 14 days |