High-resolution CE-MRA of Children's Hip Joint

Study Overview
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Brief Summary
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The goal of this observational study is to learn about the feasibility of enhanced three-dimensional water-selective cartilage (3D-WATSc) sequence in displaying the vessels of children's hip by magnetic resonance. The main questions it aims to answer are: Could the images of enhanced 3D-WATSc sequence show the healthy side hip joint vessels in children? Could the images of enhanced 3D-WATSc sequence show the vascular disease of the suffering side hip joint in children? Participants with unilateral hip disease will undergo the magnetic resonance examination including enhanced 3D-WATSc sequence. The pelvic plain film and magnetic resonance images will be collected and analysed. Researchers will compare the images of of the normal side with the images of the abnormal side to see if the enhanced 3D-WATSc sequence images could show the vascular disease of the suffering side hip joint in children?

Official Title
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High-resolution Contrast-enhanced Magnetic Mesonance Angiography of Children's Hip Joint

Conditions
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Hip, Vessels; Anomaly, Magnetic Resonance, Three-dimensional Water-selective Cartilage (3D-WATSc)

Intervention / Treatment
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* Other: Magnetic resonance examination


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Children aged 6 months-14 years who are diagnosed as hip disease after screening by pediatric orthopedic surgeon in Children's Hospital of Chongqing Medical University during the study period. The hip disease contain developmental dysplasia of the hip, Perthes disease, infection of the hip, inflammation of the hip, fracture of the hip, and Meyer's dysplasia. Exclusion Criteria: patients with bilateral hip joint disease; patients with claustrophobia;Patients with metal implants (such as pacemaker implantation)

Ages Eligible for Study
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Minimum Age: 6 Months
Maximum Age: 14 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Normal hip joint<br>The normal side of patients with hip joint disease | Other: Magnetic resonance examination<br>* the two groups are underwent magnetic resonance examination including enhanced 3D-WATSc sequence<br>|
| Abnormal hip joint<br>The abnormal side of patients with hip joint disease | Other: Magnetic resonance examination<br>* the two groups are underwent magnetic resonance examination including enhanced 3D-WATSc sequence<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The medial circumflex femoral artery (MCFA) and lateral circumflex femoral artery (LCFA) of the bilateral hip joint | Morphology of the MCFA and LCFA of the bilateral hip joint | 1 day (Magnetic resonance examination end time) | 
| The branches of the MCFA and/or LCFA around the bilateral femoral neck | Morphology of MCFA and/or LCFA branches around the bilateral femoral neck | 1 day (Magnetic resonance examination end time) | 
| The vessels of secondary ossification center and/or cartilaginous vascular canal in bilateral femoral head | Morphology of the vessels and cartilaginous vascular canal in bilateral femoral head | 1 day (Magnetic resonance examination end time) |