Online Tai Chi Intervention to Promote Smoking Cessation Among Cancer Survivors

Study Overview
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Brief Summary
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This clinical trial evaluates an online Tai Chi intervention to promote smoking cessation among cancer survivors. Tai chi is a practice that involves a series of slow gentle movements and physical postures, a meditative state of mind, and controlled breathing. It is a gentle form of exercise that can be done while sitting or standing and does not involve any medications or medical procedures. Tai chi originated as an ancient martial art in China. Over the years, it has become more focused on health promotion and rehabilitation. The use of Tai Chi may be beneficial for cancer patients who want to quit smoking.

Detailed Description
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PRIMARY OBJECTIVE: I. To assess the feasibility of the Tai Chi intervention to promote smoking cessation among cancer survivors. SECONDARY OBJECTIVE: I. Collect preliminary RCT data on the efficacy of our Tai Chi intervention for the potential of scaling up to a more extensive study. OUTLINE: Participants are randomized to 1 of 2 arms. ARM I: Participants receive access to the online WaQi program to practice Tai Chi supervised and home-based over 8 weeks. Participants also receive standard cessation treatment that includes a prescription or recommendation for nicotine replacement therapy (NRT) and undergo carbon monoxide (CO) testing on study. ARM II: Participants receive standard cessation treatment that includes a prescription or recommendation for NRT and undergo CO testing on study. Participants also receive an 8-week online Tai Chi self-administered teaching module subscription at the end of the study.

Official Title
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A Tai Chi Intervention to Promote Smoking Cessation Among Cancer Survivors

Conditions
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Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm

Intervention / Treatment
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* Other: Best Practice
* Procedure: Carbon Monoxide Measurement
* Other: Internet-Based Intervention
* Drug: Nicotine Replacement
* Other: Survey Administration
* Other: Tai Chi


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Cancer survivors (at least 3 months post-treatment, treatments include surgery, chemo, radiation, immuno-therapy) Adults aged 21 years and older Report smoking cigarettes in the past 30 days Report at least moderate interest in quitting smoking (> =3 on a Likert type scale with 5 being very extremely interested) Can participate in Zoom calls for orientation and intervention Exclusion Criteria: Non-cancer patients or cancer patients who haven't had any treatment, or the last treatment the patient had is within 3 months at participant screening) Patients under 21 years old Non-smokers in the past 30 days Report lower than moderate interest in quitting smoking (< 3 on a Likert type scale with 5 being very extremely interested) Cannot to participate Zoom calls for orientation and intervention Eligible, but sampling quotas full

Ages Eligible for Study
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Minimum Age: 21 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Arm I (Tai Chi)<br>Participants receive access to the online WaQi program to practice Tai Chi supervised and home-based over 8 weeks. Participants also receive standard cessation treatment that includes a prescription or recommendation for NRT and CO testing on study. | Other: Best Practice<br>* Receive standard cessation treatments<br>* Other names: standard therapy;Procedure: Carbon Monoxide Measurement<br>* Undergo CO test<br>* Other names: CMONOX;Other: Internet-Based Intervention<br>* Receive access to WaQi program<br>Drug: Nicotine Replacement<br>* Receive referral for NRT<br>* Other names: NRT;Other: Survey Administration<br>* Ancillary studies<br>Other: Tai Chi<br>* Practice Tai Chi<br>|
| Active Comparator: Arm II (Standard cessation)<br>Participants receive standard cessation treatment that includes a prescription or recommendation for NRT and undergo CO testing on study. Participants also receive an 8-week online Tai Chi self-administered teaching module subscription at the end of the study. | Other: Best Practice<br>* Receive standard cessation treatments<br>* Other names: standard therapy;Procedure: Carbon Monoxide Measurement<br>* Undergo CO test<br>* Other names: CMONOX;Other: Internet-Based Intervention<br>* Receive access to WaQi program<br>Drug: Nicotine Replacement<br>* Receive referral for NRT<br>* Other names: NRT;Other: Survey Administration<br>* Ancillary studies<br>Other: Tai Chi<br>* Practice Tai Chi<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| CO verification | Will be assessed by the amount of carbon monoxide in a participant's breath using a portable carbon monoxide monitor (iCOquit), which can be plugged into participants' smartphones. | Up to 6 months post-intervention | 
| Cigarette Dependence Scale (12 item) | This outcome will be assessed by the participants completing self-administered online survey that includes 12 questions. | Up to 6 months post-intervention | 
| Hospital Anxiety and Depression Scale | This outcome will be assessed by the participants completing a self-administered online survey that includes 14 questions. | Up to 6 months post-intervention | 
| Physical Activity (7 item) | This outcome will be assessed by the participants completing self-administered online survey that includes 7 questions. | Up to 6 months post-intervention |