Carpal Tunnel Syndrome Evaluation With Ultrasound in Rheumatoid Arthritis Patients

Study Overview
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Brief Summary
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In rheumatoid arthritis (RA) patients, the diagnosis of Carpal tunnel syndrome (CTS) was made based on clinical findings and physical examinations. Then, the cross-sectional areas of the participants' median nerves from different levels were measured. Meidolateral and anteroposterior diameter were measured at the level of the carpal tunnel inlet. Flattening ratio was calculated. wrist to forearm ratio and wrist to forearm difference were calculated. The obtained data were compared between RA with CTS, RA without CTS and healthy control.

Official Title
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Ultrasound Evaluation of the Median Nerve in Patients With Rheumatoid Arthritis and Its Relationship With Disease Activity

Conditions
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Median Nerve Entrapment

Intervention / Treatment
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* Diagnostic Test: Ultarsound


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: RA patients identified according to the 2010 American College of Rheumatology/Europan Leage Against Rheumatism classification criteria healthy controls (HC) with no history of rheumatic diseases and CTS. Individuals aged 18-65 years. Exclusion Criteria: thoese with hypothyroidism, gout, diabetes mellitus, history of CTS surgery, upper extremity plexopathy, polinöropathy, uncontrollable fibromyalgia, steroid injection for CTS For the HC group, those with phalen or tinnel detected in at least one wrist and those with bifid median nerve detected during US evaluation were not included in the study.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| group 1: RA without CTS<br>Rheumatoid arthritis patients without a diagnosis of CTS based on clinical findings and physical examination | Diagnostic Test: Ultarsound<br>* Median nerve evaluation of participants with ultrasound<br>|
| group 2: RA with CTS<br>Rheumatoid arthritis patients with a diagnosis of CTS based on clinical findings and physical examination | Diagnostic Test: Ultarsound<br>* Median nerve evaluation of participants with ultrasound<br>|
| group:3 Healthy Control<br>Healthy Control without rheumatologic disease and Carpal tunnel syndrome | Diagnostic Test: Ultarsound<br>* Median nerve evaluation of participants with ultrasound<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Comparison of US findings among participants | Comparison of US findings among participants | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Relationship between US findings and disease activity in the patient group | The correlation between the US findings of the participants in the patient group and the CDA, which evaluates disease activity, was examined. | 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Rheumatoid arthritis, Ultrasound, Carpal Tunnel Syndrome