Effectiveness of the Anatomical Snuff Box Approach for Coronary Angiography

Study Overview
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Brief Summary
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The main objective of the study is to assess whether the distal radial arterial approach (snuff box or back of the hand) is not inferior to the radial arterial approach at the wrist, in the management of coronary angiography for diagnostic purposes

Detailed Description
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Coronary angiography is the reference examination for anatomical exploration coronary arteries to determine the presence or absence of a predominantly obstructive coronary disease. Historically, the femoral approach was the most common approach used in interventional cardiology. The radial approach to the forearm presents multiple advantages over the femoral route, and it became the gold standard approach to coronary angiography and intervention percutaneous coronary. Although uncommon, vascular complications related to the radial pathway exist. This is why a more distal radial approach, above the long tendon extensor of the thumb (at the level of the anatomical snuff box) or downstream (at the back of the hand) was suggested more than 10 years ago. This pathway is now an advantageous alternative to the radial approach of first intention, both for the patient and for the practitioner. The two procedures are common today but few studies have been developed to compare the two approaches. Therefore, the main objective of the study is to assess whether the distal radial arterial approach (snuff box or back of the hand) is not inferior to the radial arterial approach at the wrist, in the management of coronary angiography for diagnostic purposes

Official Title
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Effectiveness of the Anatomical Snuff Box Approach for Coronary Angiography: Comparative Non-inferiority Study With the Radial Arterial Approach to the Wrist

Conditions
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Coronary Angiography

Intervention / Treatment
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* Procedure: Coronary angiography


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patient, male or female, aged 18 and over Patient having a diagnostic coronary angiography programmed by radial route. Patient with a radial pulse at the anatomical snuff box and at the wrist noticeable Exclusion Criteria: Patient requiring emergency coronary angiography or having an acute coronary syndrome Patient with severe arteriopathy of the supra-aortic trunks Patient with a history of coronary bypass surgery Tall patients (>1.90m) Patient allergic to xylocaine Patient presenting a contraindication to the realization of a coronary angiography: terminal IRC, pregnancy, severe sepsis....

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Snuff box puncture<br>Puncture of the radial artery at of the anatomical snuff box or on the back of the hand during coronary angiography | Procedure: Coronary angiography<br>* Snuff Box Approach or radial Arterial Approach at wrist for coronary angiography.<br>|
| Active Comparator: Wrist puncture<br>Puncture of the radial artery at the level of the base of the wrist during coronary angiography | Procedure: Coronary angiography<br>* Snuff Box Approach or radial Arterial Approach at wrist for coronary angiography.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Success rate of coronary angiography without changing puncture route. | The primary endpoint is the success rate of coronary angiography without changing puncture route. | 1 day |