linjc16/ctgov huggingface dataset:
Thigh Muscle Mass and Muscle Wasting in Patients in the Emergency Department

Study Overview
=================
Brief Summary
-----------------
The goal of this observational study is to evaluate whether thigh muscle mass and muscle wasting are associated with mortality in patients who visit the emergency department. The main questions it aims to answer are: Is thigh muscle mass associated with mortality in patient who visit the emergency department? Does muscle wasting exist during staying in the emergency department? Is muscle wasting associated with mortality in patient who visit the emergency department? Participants will be evaluated for serial thigh muscle mass using point-of-care ultrasound at the emergency department.

Official Title
-----------------
Thigh Muscle Mass and Muscle Wasting in Patients in the Emergency Department

Conditions
-----------------
Sepsis, Cardiac Arrest, Acute Respiratory Failure, Patients Who Visit Emergency Department, Shock, Trauma

Intervention / Treatment
-----------------
* Other: Thigh muscle mass and muscle wasting (exposure)


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients who visit the emergency department of Korea University Ansan Hospital during study period patients with age within the limits patients who are willing to be participate the study with informed consent patients who undergo point-of-care ultrasound to evaluate thigh muscle mass Exclusion Criteria: patients with age out of limits patients who have deformities on lower leg patients who is unable to maintain appropriate position to undergo point-of-care ultrasound patients who decline to participate the study patients who have 'do-not-resuscitate' order or are not willing to be resuscitated patients of whom point-of-care ultrasound on thigh muscle mass was not performed

Ages Eligible for Study
-----------------
Minimum Age: 19 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Thigh muscle mass and muscle wasting (exposure)|Thigh muscle mass and muscle wasting (exposure variable)|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 28 day mortality | 28 day mortality | 28 days after study enrollment |
Prevalence of Stress Urinary Incontinence in Obese Versus Non-obese Nulligravid Women

Study Overview
=================
Brief Summary
-----------------
Urinary incontinence (UI) is more common than any other chronic disease. Stress urinary incontinence (SUI), among the various forms of urinary incontinence, is the most prevalent (50%) type of this condition. Female urinary continence is maintained through an integrated function of pelvic floor muscles (PFMs), fascial structures, nerves, supporting ligaments, and the vagina. In women with SUI, the postural activity of the PFMs is delayed, and the balance ability is decreased. Many women, by learning the correct timing of a pelvic floor contraction during a cough, are able to eliminate consequent SUI. Timing is an important function of motor coordination and could be affected by proprioception. We aim to assess stress urinary incontinence in obese and non-obese Nulligravid females.

Official Title
-----------------
Prevalence of Stress Urinary Incontinence in Obese Versus Non-obese Nulligravid Women

Conditions
-----------------
Stress Urinary Incontinence

Intervention / Treatment
-----------------
* Other: ICIQ-UI SF questionnaire


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Women aged between18 and 45 years. Non obese females with BMI <25kg/m2. Obese females with BMI ≥30kg/m2. Nulligravid females. Exclusion Criteria: Multiparous Females Patients with active urinary tract infection. Patients with respiratory or neurological diseases. Patients with communication problems, cognitive disorders & mental disturbance. Current treatment with drugs (benzodiazepines, diuretics) Patients who underwent any previous abdominal or pelvic surgery.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
-----------------
Female

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Obese<br>BMI>30 | Other: ICIQ-UI SF questionnaire<br>* validated arabic short form of ICIQ on urinary incontinence<br>|
| Non-obesse<br>BMI<25 | Other: ICIQ-UI SF questionnaire<br>* validated arabic short form of ICIQ on urinary incontinence<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prevalence of Stress Urinary Incontinence in Obese Versus Non-obese Nulligravid Women | as detected by questionnaire score | 6 months |
Medication Use Evaluation (MUE) for Continuous Heparin Infusions in Hospitalized Patients

Study Overview
=================
Brief Summary
-----------------
Unfractionated heparin (UFH) is an anticoagulant to prevent thrombus formation or worsening of an existing thrombus. It is indicated for patients with deep vein thrombosis/pulmonary embolism (DVT/PE) or acute coronary syndrome (ACS). Unfractionated heparin treatment consists of an initial bolus followed by a continuous infusion that is adjusted based on the patient's subsequent partial thromboplastin time (PTT) levels

Detailed Description
-----------------
Unfractionated heparin is classified as a high-alert medication in the acute care setting.3 Therapeutic anticoagulation is a high priority for healthcare teams because the impacts of inadequate anticoagulation can lead to life threatening events such as a major bleed or thrombus formation and/or death.

Official Title
-----------------
Medication Use Evaluation (MUE) for Continuous Heparin Infusions in Hospitalized Patients

Conditions
-----------------
Unfractionated Heparin

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patient's aged 18 years or older with a confirmed diagnosis of DVT/PE based on imaging or a confirmed diagnosis of ACS requiring heparin therapy Exclusion Criteria: History of bleeding in the last 30 days History of HIT Use of systemic anticoagulants for another indication Presence of coagulation disorder prior to admission (i.e. hemophilia, sickle cell anemia, etc.)

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidents of deviations from protocol | Appropriate anticoagulation management will be measured using Percent time in therapeutic range based on aPTT levels | 30 Days |
Don't Treat Ghosts Anti-MRSA Antibiotics in Osteomyelitis Without Identified MRSA

Study Overview
=================
Brief Summary
-----------------
Osteomyelitis is described as infection and inflammation of the long bone or bone marrow, often due to an open wound, operation, or invasive trauma.1 It is invasive and involves hematogenous seeding or contiguous spread of the infectious organism

Detailed Description
-----------------
This disease can be classified by location of infection, extent of spread, chronicity, and source of infection.3,4 Osteomyelitis can be caused by a variety of organisms, most commonly gram-positive staphylococci. Osteomyelitis is associated with a high rate of relapse, high disease burden, and high health care costs.3 Following confirmation of disease via imaging and histopathologic examination, treatment consists of antibiotic therapy and, often, surgical intervention.3,5,6 Treatment with antibiotic therapy is often administered for 4-6 weeks when surgical intervention is not performed.6 Antibiotic selection should be guided by microbiology and antimicrobial susceptibilities.4 Thirty to sixty percent of osteomyelitis cases are caused by Staphylococcus aureus.

Official Title
-----------------
Don't Treat Ghosts: Anti-MRSA Antibiotics in Osteomyelitis Without Identified MRSA

Conditions
-----------------
Osteomyelitis

Intervention / Treatment
-----------------
* Drug: Anti-MRSA therapy


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: • Admission to any MHS hospital between April 1, 2017 and April 1, 2023 > 18 years of age Documented osteomyelitis location of the lower limb via ICD-10 code Documented imaging of lower limb osteomyelitis during index admission Planned intravenous (IV) antibiotics for at least 4 weeks Exclusion Criteria: • IV antibiotics for less than 24 hours inpatient Planned surgical intervention documented at admission Patients receiving monotherapy with an anti-MRSA agent Positive MRSA culture during index admission Current outpatient antibiotic use on index admission Repeated hospital admission during study period

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: Anti-MRSA therapy|chart review to determine the clinical outcomes of patients with osteomyelitis who were placed on definitive anti-MRSA treatment, despite no identified MRSA cultures.|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Comparison of treatment | the comparison of treatment failure between anti-MRSA therapy and no anti-MRSA therapy defined as a composite of hospital readmission for osteomyelitis within 180 days of antibiotic initiation | 180 Days |
Follow-up of Cell Changes in the Cervix

Study Overview
=================
Brief Summary
-----------------
The purpose of the study is to follow up on cell changes detected in the cervical cancer screening program, to investigate whether they are handled with adequate quality.

Detailed Description
-----------------
The aim of the study is to clarify whether follow-up of cell changes is carried out with sufficiently good quality. It is nationally recommended to perform an HPV test on mild cell changes and only refer to clinical follow-up if you are HPV positive. Descriptive statistics on HPV-testing and follow-up of quality are not available today. If HPV testing has not already been performed, archived samples with glandular cell changes will be HPV-analyzed in Cobas 4800 HPV-polymerase chain reaction (PCR), which shows data on the presence of HPV and Luminex-PCR, which shows which HPV types the samples have. Women with low-grade squamous cell changes (ASCUS and CIN1) with simultaneous HPV analysis will be followed up with data from the Swedish National Cervical Screening Registry (NKCx) from the last ten years. A register linkage with data from NKCx and the National Cancer Registry at the National Board of Health and Welfare will be carried out to determine which women have developed gynecological cancer, cervical cancer and/or pre-cancer (cancer in situ). A follow-up review of reported original cytological (cell samples) and histological (tissue samples) diagnoses will be performed by cytodiagnostics and cytopathologists, to verify the correct diagnosis. Statistics on collection of non-organized cell samples after a partial negative sample where follow-up is not recommended are produced in aggregated form in the form of an extract from NKCx

Official Title
-----------------
Follow-up of Cell Changes in the Cervix

Conditions
-----------------
Cancer of Cervix

Intervention / Treatment
-----------------
* Diagnostic Test: HPV genotyping


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: women with an AGC diagnosis between February 17, 2014 and December 31, 2018 23-80 years old resident of the Stockholm-Gotland region of Sweden Exclusion Criteria: -

Ages Eligible for Study
-----------------
Minimum Age: 23 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Women aged 26-80 with atypical glandular cell (AGC) cytology result<br>Women in the capital region of Sweden with AGC, a concomitant human papillomavirus (HPV) analysis, and a histopathology. | Diagnostic Test: HPV genotyping<br>* HPV genotyping of samples classified that were positive for other HPV<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| cervical intraepithelial neoplasia 3 (CIN3+) | Risk for developing CIN3+ or worse depending on HPV type | 2014-2018 |
Prevalence of OSA in Patients of ILD

Study Overview
=================
Brief Summary
-----------------
To evaluate the clinical predictors of OSA in patients with ILD

Detailed Description
-----------------
Interstitial lung diseases (ILDs) are a group of heterogeneous disorders characterized by varying degrees of fibrosis and inflammation of lung parenchyma. Obstructive sleep apnea is a type of sleep disordered breathing characterized by repeated episodes of apnea and hypopnea during sleep due to narrowing or occlusion of the upper airway. It was found that the prevalence of OSA is as high as 80% among patients with idiopathic pulmonary fibrosis (IPF). Despite this common association, there is limited research in this field. There is great need for further studies to highlight this association and understand the underlying pathophysiological mechanisms implicated in those patients, to ultimately guide the appropriate management.

Official Title
-----------------
Pattern Of Association Between Obstructive Seep Apnea and Interstitial Lung Disease

Conditions
-----------------
OSA

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients presented to Chest Department with interstitial lung disease will be included, screened for OSA. Exclusion Criteria: Age: less than 18 years. Unstable patients or need for ICU admission

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Predictors of OSA in patients with ILD | By clinical history ,examination, BMI | Baseline | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prevalence of OSA among patients with ILD Presented To Chest Department in Assiut University Hospital | BY Polysomnography | base line |
Infuence of Kinesiotaping on Pulmonary Function Improvement in Multiple Rib Fracture

Study Overview
=================
Brief Summary
-----------------
Elastic tapes, named kinesiotapes have a limited, but proven influence on pain reduction, improvement in muscular strength and joint function. It can be hypothetised that by using kinesiotape techniques on damaged chest wall (due to mostly rib fracture) we can improve not only analgesia, but also improve lung function tests and speed recovery.

Detailed Description
-----------------
Chest wall injury changes the function of chest wall muscles and other structures, which in turn influences respiratory function and cause significant pain. Elastic tapes, named kinesiotapes have a limited, but proven influence on pain reduction, improvement in muscular strength and joint function. It can be hypothetised that by using kinesiotape techniques on damaged chest wall (due to mostly rib fracture) we can improve not only analgesia, but also improve lung function tests and speed recovery.

Official Title
-----------------
Infuence of Kinesiotaping on Pulmonary Function Improvement in Multiple Rib Fracture

Conditions
-----------------
Chest Wall Injury

Intervention / Treatment
-----------------
* Other: Kinesiotape placement


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Unilateral chest wall injury with multiple rib fracture (< 5 ribs) Signed informed consent Exclusion Criteria: Minors Pregnant women Contraindications of using kinesiotapes Contraindications to perform spirometry (lung function tests) Inability to cooperate Chest drains Pneumothorax

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: kinesiotape<br>Placement of kinesiotapes, using ligament techniques on the injured side of chest, focusing on the point of maximal pain. | Other: Kinesiotape placement<br>* Placement of kinesiotapes, using ligament techniques on the injured side of chest, focusing on the point of maximal pain.<br>|
| Placebo Comparator: control<br>No kinesiotape, standard of care | Other: Kinesiotape placement<br>* Placement of kinesiotapes, using ligament techniques on the injured side of chest, focusing on the point of maximal pain.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Improved spirometry tests | Improvement in lung function using spirometry | 2 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Reduction in opioid consumption | Reduction in consumtion of opioid analgetic drugs | 2 days |
A Study of Cardiovascular Disparities in the Greater Mankato Somali Community to Prevent Hypertension

Study Overview
=================
Brief Summary
-----------------
The purpose of this research is to develop ways to reduce hypertension-management-related disparities in the Greater Mankato Area Somali population.

Official Title
-----------------
Reducing Cardiovascular Disparities in the Greater Mankato Somali Community by Utilizing Community-based Interventions to Build Capacity Within the Community to Identify, Manage and Prevent Hypertension

Conditions
-----------------
Hypertension

Intervention / Treatment
-----------------
* Behavioral: Health Education
* Other: Home Blood Pressure Monitor


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Greater Mankato Somali community members. Non-pregnant. At the Mosque or Halal stores between 5/2/2022-5/31/2023. Exclusion Criteria: Pregnant. Are not at the Mosque or Halal stores between 5/2/2022-5/31/2023.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Health Services Research
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Treatment Group<br>Participants will be given access to health education, home blood pressure monitor, and referral to a primary care provider. | Behavioral: Health Education<br>* Education materials on high blood pressure, lowering sodium, starting an exercise program, and weight management.<br>Other: Home Blood Pressure Monitor<br>* Blood pressure cuff for home use<br>|
| No Intervention: Control Group<br>Participants receive referrals only to a primary care provider (PCP) for blood pressure monitoring. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes in blood pressure | Measured in millimeters of mercury (mmHg) | Baseline, 3 weeks, 3 months | 
| Change in Primary Care Provider status | Number of subjects to follow up with a primary care provider | Baseline, 3 weeks, 3 months |
Digitally Delivered Exercise in Helping People to Move More

Study Overview
=================
Brief Summary
-----------------
The main objective of this study is to examine the influence of the digital exercise prescription platform in increasing habitual physical activity in people on a weight management programme.

Detailed Description
-----------------
Participants will be provided with individualised exercise training from exercise specialists. Participants will be recruited from the BCUHB NHS KindEating programme for people who have obesity (BMI of >30 kg/m2). Participants will be recruited remotely, via their KindEating dietitian. The assessments and exercise programme will be conducted remotely in the participants' own home.

Official Title
-----------------
Salaso Moving More: The Impact of Digitally Delivered Precision Exercise in Helping People to Move More

Conditions
-----------------
Obesity

Intervention / Treatment
-----------------
* Behavioral: Exercise


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Enrolled into the KindEating programme with BCUHB ≥ 18 years of age Able to provide written informed consent Exclusion Criteria: Any uncontrolled medical condition that is exacerbated by exercise Unstable angina, unstable or acute heart failure, new or uncontrolled arrhythmias, resting or uncontrolled tachycardia, uncontrolled hypertension >180/100 (in either), symptomatic hypotension, febrile illness, acute uncontrolled psychiatric illness, other rapidly progressing terminal illness, uncontrolled diabetes >16.7mmol, patient's currently undergoing anti-biotic treatment for cellulitis, acute infections active foot ulceration Inability to provide informed consent

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Exercise<br>Remote 12-week exercise intervention | Behavioral: Exercise<br>* Individualised remote exercise intervention<br>|
| No Intervention: Control/Routine Care<br>No exercise intervention, continue with routine care | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Habitual physical activity | Global Physical Activity Questionnaire | Change between baseline and 3 months (post intervention) | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Physical activity