Physical Parameters in Osteoarthritis Stages

Study Overview
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Brief Summary
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To investigate the extent to which pain, functionality, and quality of life change over the progression of osteoarthritis grades.

Official Title
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Effects Of Osteoarthritis Grades On Pain, Function, And Quality Of Life

Conditions
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Pain, Osteoarthritis, Quality of Life

Intervention / Treatment
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* Diagnostic Test: Radiographic classification


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: having the same OA grade in both knees volunteering to participate in the study not having undergone previous lower extremity surgery Exclusion Criteria: neurological disorders; those with a history of surgery related to the lower extremities; those with orthopedic problems in the lower extremities, such as tendinopathy and bursitis; those who had neurological, orthopedic, or cognitive disorders that would prevent walking; those with a diagnosis of diabetes, obesity, or rheumatological disorders; those who had received intra-articular injection therapy within the last three months; and those with malignancy or perception problems.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Grade 1 osteoarthritis<br>disease stages 1 according to the Kellgren-Lawrence radiographic classification system | Diagnostic Test: Radiographic classification<br>* disease stages ranged from 1 to 4 according to the Kellgren-Lawrence radiographic classification system<br>|
| Grade 2 osteoarthritis<br>disease stages 2 according to the Kellgren-Lawrence radiographic classification system | Diagnostic Test: Radiographic classification<br>* disease stages ranged from 1 to 4 according to the Kellgren-Lawrence radiographic classification system<br>|
| Grade 3 osteoarthritis<br>disease stages 3 according to the Kellgren-Lawrence radiographic classification system | Diagnostic Test: Radiographic classification<br>* disease stages ranged from 1 to 4 according to the Kellgren-Lawrence radiographic classification system<br>|
| Grade 4 osteoarthritis<br>disease stages 4 according to the Kellgren-Lawrence radiographic classification system | Diagnostic Test: Radiographic classification<br>* disease stages ranged from 1 to 4 according to the Kellgren-Lawrence radiographic classification system<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual Analog Scale (VAS) | a 10-cm straight line with 0 on one end indicating no pain and 10 on the other end signifying unbearable pain. The participants were asked to mark the intensity of their current pain on the line | 2 minutes | 
| two-minute walk test (2MWT) | A 45-meter corridor was used for the 2MWT. The start and end points were marked, and the participants were asked to walk at a normal pace within these boundaries. The distance covered in two minutes was recorded | 2 minutes | 
| Western Ontario and McMaster Universities Osteoarthritis Index | The questionnaire consists of 24 items, each scored from 0 to 4. The total score is obtained by summing the point equivalents of the responses given to all items. A higher score indicates poorer functionality | 10 minutes | 
| Nottingham Health Profile (NHP) | This tool comprises 38 questions in six domains, namely energy, pain, social isolation, physical mobility, emotional reactions, and sleep. Each domain is scored from 0 to 100. The total score is obtained by summing the scores obtained from the six domains. High scores indicate a good quality of life. | 10 minutes |