Qualitative Analysis of Interviews Between Pharmacist and Elderly Patients Treated With Antithrombotics for an Ischemic Stroke.

Study Overview
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Brief Summary
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Cerebrovascular accident is the 2nd leading cause of death and the leading cause of disability in the world. There are brakes and levers of medication adherence in the context of secondary prevention treatment in stroke.

Detailed Description
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Cerebrovascular accident is the 2nd leading cause of death and the leading cause of disability in the world. The probability of stroke recurrence is high: about 25% the first year , and 30 to 40% in the 5 years following the stroke. Recurrent strokes are responsible for significant disability, institutionalization, major neurocognitive disorders, and death. In order to reduce the risk of stroke recurrence, multiple secondary prevention strategies have demonstrated their effectiveness, such as the prescription of drugs (in particular statins and antithrombotics), the establishment of a balanced diet, the practice of an activity physical, or even tobacco addiction. However, the effectiveness of these strategies is optimal if and only if patients adhere to them. In addition, previous studies have focused on the brakes and levers of medication adherence in the context of secondary prevention treatment in stroke. In elderly patients, other obstacles could have been identified by specific studies, such as cognitive, sensory, functional disorders or even isolation.

Official Title
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Qualitative Analysis of Interviews Between Pharmacist and Elderly Patients Treated With Antithrombotics for an Ischemic Stroke.

Conditions
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Stroke

Intervention / Treatment
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* Other: Analysis of the verbatim from the transcription of the recorded interviews.


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients aged 65 and over Patients hospitalized for an ischemic stroke or a recurrence of ischemic stroke, already being treated with an antithrombotic treatment (antiplatelet agent or anticoagulant ) prior to the stroke Patients living at home and with a plan to return home. Patients who did not object to the study and who gave their consent for the recording of the interview Exclusion Criteria: Patients with cognitive disorders or stroke sequelae that do not allow a semi-directive interview to be carried out (at medical discretion). Non-French speaking patients

Ages Eligible for Study
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Minimum Age: 65 Years
Maximum Age: 100 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients having had a stroke<br>elderly patients previously treated with an antithrombotic and admitted to hospital for an ischemic stroke | Other: Analysis of the verbatim from the transcription of the recorded interviews.<br>* recorded semi-structured interviews between the patients and the pharmacist<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Analysis of the verbatim from the transcription of the recorded interviews. | Describing the content of discussions, relating to antithrombotic treatment for secondary prevention, between elderly patients previously treated with antithrombotics and admitted to hospital for an ischemic stroke and a pharmacist | one year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Analysis of verbatim statements from the transcription of recorded interviews on patients' representations and beliefs regarding antithrombotics | Exploring patients' representations and beliefs regarding antithrombotics before and after the onset of stroke or recurrence of stroke | 15 to 60 minutes per patient | 
| Analysis of verbatim statements from the transcription of recorded interviews on patients' medication adherence to antithrombotics | Explore patients' medication adherence to antithrombotics before the onset of stroke or recurrence of stroke | 15 to 60 minutes per patient | 
| Analysis of verbatim statements from the transcription of recorded interviews on the impact of the occurrence of stroke or recurrence of stroke on medication adherence | Explore the impact of stroke occurrence or stroke recurrence on patient medication adherence (including motivation, ambivalence, confidence in medication benefits) | 15 to 60 minutes per patient | 
| Analysis of verbatim statements from the transcription of recorded interviews on the obstacles and levers to medication adherence | Identify the barriers and levers to drug adherence with antithrombotics | 15 to 60 minutes per patient | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Qualitative study, semi-structured interview, antithrombotic, stroke, medication adherence