linjc16/ctgov huggingface dataset:
Oral Fluid Intake After Extubation

Study Overview
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Brief Summary
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According to the current guidelines the patient is not allowed to drink any fluid at least 2 hours after extubation to prevent complications. However there is no evidence in the literature to support this approach. Because anaesthetic drugs and their side effects changed significantly from their first usage, the investigators can assume that existing approach is obsolete and has no place anymore in the modern medicine. Keeping patient n.p.o (nothing per os) for 2 hours after extubation may lead to patient´s thirst or other discomfort. The aim of the study is to detect whether early oral fluid intake after extubation could lead to safe relief of thirst and to better patient´s comfort overall.

Detailed Description
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Everything stated in the brief summary.

Official Title
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Early Versus Delayed Oral Fluid Intake Initiation (Sipping) After Extubation, Influence on the Feeling of Thirst, Patient Comfort and the Occurrence of Complications.

Conditions
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Intubation

Intervention / Treatment
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* Behavioral: Fluid intake not as per standard guidlines


Participation Criteria
=================
Eligibility Criteria
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Inclusion Criteria: patients with planned extubation assigned to the study able to swallow the fluid willing to participate the study Exclusion Criteria: patients after upper digestive tract surgery patients after trachea surgery patients with possible neurological deficiency patients after VIII. cranial nerve surgery patients not able to swallow
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Early fluid intake<br> | Behavioral: Fluid intake not as per standard guidlines<br>* The participant will be randomized into two arms. After the randomization one arm will get the per os fluid intake before the standard time frame.<br>|
| Other: Standard Delayed oral fluid<br> | Behavioral: Fluid intake not as per standard guidlines<br>* The participant will be randomized into two arms. After the randomization one arm will get the per os fluid intake before the standard time frame.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Assessment of presence or absence of thirst 120 minutes after extubation | Between both groups the presence of anpleasent feeling of thirst will be assessed and compared | During procedure (120 minutes after extubation) |
Ulcer Bleeding After Band Ligation of Esophageal Varices

Study Overview
=================
Brief Summary
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Primary Outcomes: assessment of incidence , risk factors and prognosis of post-banding ulcer bleeding following EVL in patients with liver cirrhosis. Secondary Outcomes: minimize post-banding ulcer bleeding

Detailed Description
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Esophageal variceal bleeding represents the most vital complication among patients with liver cirrhosis at rate of 5-15% per year. Endoscopic variceal ligation (EVL), either used as therapeutic in emergency or as prophylactic, is one of the best modalities used in EV treatment. The procedure is effective and generally safe. After banding, a superficial ulcer is formed, which usually heals in 2-3 weeks. The main complications of variceal banding are pain, dysphagia, fever, bleeding during the procedure and post banding ulcer bleeding (PBUB). The prevalence of PBUB is reported to be 3.6-15% . Rebleeding can be fatal, and is mainly resulted from early spontaneous slippage of the rubber bands, before occlusion of the varix with a mature thrombus, leaving an unhealed ulcer . The time frame of variceal rebleeding can be divided into very early rebleeding (within 5 days of acute bleeding), early rebleeding (within 6 weeks of acute bleeding), and delayed rebleeding. Previous reports showed that early rebleeding ranged from 30% to 40% within the first 6 weeks, and was significantly associated with the risk of death within 6 weeks. Therefore, the aim of this research is assessment of incidence , risk factors and prognosis of post-banding ulcer bleeding following EVL in patients with liver cirrhosis, in order to minimize post-banding ulcer bleeding.

Official Title
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Ulcer Bleeding After Band Ligation of Esophageal Varices:Risk Factors and Prognosis

Conditions
-----------------
Esophageal Varices

Participation Criteria
=================
Eligibility Criteria
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Inclusion Criteria: Patients' age is 18 years or above. Patient who are diagnosed with esophageal varices by upper endoscopy. Patient who are fit for surgery to undergo endoscopic banding procedure. Exclusion Criteria: Pediatric patients. patient refuse to participate at this study

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| assessment of incidence , risk factors and prognosis of post-banding ulcer bleeding following EVL in patients with liver cirrhosis. | assessment of incidence , risk factors and prognosis of post-banding ulcer bleeding following EVL in patients with liver cirrhosis. | Baseline |
Comparison of Marginal Fit and Internal Adaptation in All-Metal Crowns: An In Vitro Experimental Trial

Study Overview
=================
Brief Summary
-----------------
The goal of this in vitro study is to compare the marginal fit and internal adaptation of all-metal crowns in polished crown preparations and non-polished crown preparations The main question it aims to answer is: are the non polished tooth preparations comparable to polished preparations? We will compare polish and non polish groups and see their effects on marginal fit and internal adaptation of all metal crown

Official Title
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Comparison of Marginal Fit and Internal Adaptation in All-Metal Crowns: An In Vitro Experimental Trial

Conditions
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Evaluation of Marginal and Internal Fit of Metal Crowns

Intervention / Treatment
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* Other: microleakage


Participation Criteria
=================
Eligibility Criteria
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Inclusion Criteria: Phantom teeth Maxillary molars Metal crowns with conventional lost-wax technique for crown fabrication Exclusion Criteria: Over prepared or underprepared crowns Defective metal crowns Ruptured silicone films upon removal Defective die stone casts
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| NP is given to the non polished group which is group 2<br>Out of two groups, group 2 is a test group to which rough preparations are assigned | Other: microleakage<br>* prevention of microleakage and secondary carries<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| marginal fit | The margins of fixed restorations refers to the junction between the prepared tooth structure and the crown restoration | six months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Internal fit | Internal fit is defined as the perpendicular distance between the framework and abutment teeth and the misfit is measured from occlusal/incisal and axial surfaces to the coping | six months |
Positron Emission Tomograph(PET) Imaging Explores the Role of SF-DEVD-2 in Monitoring Tumor Efficacy

Study Overview
=================
Brief Summary
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This is a single arm study to determining the value of apoptotic molecular probe SF-DEVD-2 in the early evaluation of tumor efficacy and comparing it head-to-head wihe 18F-FDG(18F-2-fluoro-2-deoxy-D-glucose)

Official Title
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PET Imaging Explores the Role of SF-DEVD-2 in Monitoring Tumor Efficacy

Conditions
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Breast Cancer Stage II, Breast Cancer Stage III, Solid Tumor

Intervention / Treatment
-----------------
* Drug: [18F]SF-DEVD-2
* Drug: [18F]-FDG


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients voluntarily signed informed consent; Age18-70, male or female; Diagnosed with stage 2 or 3 breast cancer Solid tumors、masses larger than 2cm with lymph node metastasis Pathology is HER3+、triple negative patients Patients to be treated with neoadjuvant chemotherapy Exclusion Criteria: Age greater than or equal to 70 years old Abnormal liver and kidney function (more than five times the normal value) Diagnosis level of breast cancer stage 4 or second time tumor patients

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: [18F]SF-DEVD-2<br> | Drug: [18F]SF-DEVD-2<br>* Patients will receive a tracer dose of 18F (2-4mCi) labelled SF-DEVD-2<br>Drug: [18F]-FDG<br>* Patients will receive a tracer dose of 18F (5-10mCi) labelled FDG<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluation of tissue distribution of [18F]-DEVD-2 | Biodistribution of [18F] -DEVD-2 evaluated by the maximum standardized uptake value（SUVmax) in various organs during repeated [18F]-DEVD scans will be reported. | 7 days |
Neck Joint Position Error Among Taibah Students University; Saudi Arabia; Cross Section Design

Study Overview
=================
Brief Summary
-----------------
this study was done to answer the following: Is there a difference between students without and with varying degrees of text neck in cervical proprioception defect? Is there a correlation between JPE and severity of text neck among Taibah students University?

Official Title
-----------------
Neck Joint Position Error Among Taibah Students University; Saudi Arabia; Cross Section Design

Conditions
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Proprioception

Intervention / Treatment
-----------------
* Device: inclinometer, smart phone goniometer and laser beam


Participation Criteria
=================
Eligibility Criteria
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Inclusion Criteria: A convenient sample of 68 female students the age was between 18-25 years Exclusion Criteria: Any students with neck pain or previous neck or back surgery or a history of a previous accident were excluded Also, we excluded any student with a history of fracture injury of the cervical column, scoliosis, severe thoracic kyphosis, rheumatic disease, torticollis, loss of standing balance, use of hearing aid, and persistent respiratory problems.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 25 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| normal group<br>no text neck | Device: inclinometer, smart phone goniometer and laser beam<br>* devices to objectively assess proprioception of the neck<br>|
| mild text neck<br> | Device: inclinometer, smart phone goniometer and laser beam<br>* devices to objectively assess proprioception of the neck<br>|
| moderate text neck<br> | Device: inclinometer, smart phone goniometer and laser beam<br>* devices to objectively assess proprioception of the neck<br>|
| severe text neck<br> | Device: inclinometer, smart phone goniometer and laser beam<br>* devices to objectively assess proprioception of the neck<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| neck proprioception error | we measured joint position error for all students from sitting and standing using laser beam detection error | one day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| joint position error | we measured joint position error of cervical spine by measuring neck motion by phone goniometer and inclinometer. | one day |
CT Imaging for Guiding PA-TACE for HCC

Study Overview
=================
Brief Summary
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Postoperative adjuvant transarterial chemoembolization (PA-TACE) may improve survival outcomes in a subset of patients with resected hepatocellular carcinoma (HCC), reliable biomarkers for the criterion for the selection of candidates are lacking. The present study aimed to evaluate whether CT imaging can provide more value for predicting benefit from PA-TACE.

Official Title
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CT Imaging for Guiding Postoperative Adjuvant Transarterial Chemoembolization for Hepatocellular Carcinoma

Conditions
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Carcinoma, Hepatocellular

Intervention / Treatment
-----------------
* Procedure: postoperative adjuvant transarterial chemoembolization


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: CT scans acquired no more than one month before surgery Confirmation of HCC diagnosis by pathological examination Curative surgical resection Exclusion Criteria: Prior antitumor treatment Macrovascular thrombosis or metastasis Perioperative mortality Unqualified image artifacts Tumor rupture MVI status not reported

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Hepatectomy alone<br> | Procedure: postoperative adjuvant transarterial chemoembolization<br>* HCC patients received hepatectomy and PA-TACE.<br>|
| PA-TACE<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Overall survival | Overall survival was calculated from the date of hepatectomy to the last follow-up or until death, whichever came first. | the date of hepatectomy to the last follow-up or until death, whichever came first, assessed up to 120 months. | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Carcinoma, Hepatocellular
Predictive Value of Epicardial Adipose Tissue for Pulmonary Embolism and Death in Patients With Lung Cancer

Study Overview
=================
Brief Summary
-----------------
The occurrence and progression of lung cancer is related to visceral adipose tissue (VAT). Epicardial adipose tissue (EAT) is a kind of VAT, producing a variety of inflammatory cytokines and adipokines, participating in the formation of local inflammation, promoting the formation of pre-thrombotic state, and leading to the occurrence of thromboembolism. Patients with lung cancer have increased inflammatory response and are more prone to suffer thrombosis. However, in lung cancer patients, the clinical correlation between EAT and pulmonary embolism has not been reported. Objective: To analyze the risk factors of poor prognosis in lung cancer patients with PE, and to explore the predictive value of EAT in pulmonary embolism events and death in lung cancer patients. Methods: EAT volume and density, as well as anthropometric and blood biomarkers, were evaluated in a sample of lung cancer patients, half with pulmonary embolism and half without. The incidence of adverse prognosis and related factors were followed up by telephone.

Official Title
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Predictive Value of Epicardial Adipose Tissue for Pulmonary Embolism and Death in Patients With Lung Cancer

Conditions
-----------------
Pulmonary Embolism, Lung Cancer

Intervention / Treatment
-----------------
* Diagnostic Test: CTPA (computed tomography pulmonary angiography)


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: The pathological diagnosis was lung cancer Pulmonary artery was evaluated by CTA during hospitalization. Exclusion Criteria: Patients with incomplete clinical data Patients with no follow-up data Patients with a history of PE before diagnosis of lung cancer
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| PE group<br>The CTPA diagnosis suggest pulmonary embolism | Diagnostic Test: CTPA (computed tomography pulmonary angiography)<br>* The CTPA diagnosis suggest or did not suggest pulmonary embolism.<br>|
| control group<br>The CTPA diagnosis did not suggest pulmonary embolism | Diagnostic Test: CTPA (computed tomography pulmonary angiography)<br>* The CTPA diagnosis suggest or did not suggest pulmonary embolism.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| EAT volume | volume of epicardial adipose tissue (EAT), Cm3 | May, 20, 2023 | 
| EAT density | density of epicardial adipose tissue (EAT) , Hounsfield Units (HU) | May, 20, 2023 |
Validation of Peripheral Perfusion Index in Predicting Successful Supraclavicular Brachial Plexus Block in Pediatrics

Study Overview
=================
Brief Summary
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Few data are available for the PI as a tool for evaluation of peripheral block success in pediatric patients. Furthermore, there is currently no cut-off value defined for the accuracy of the PI in the detection of successful block.

Detailed Description
-----------------
modify plan for intraoperative and postoperative analgesia. Perfusion index is an assessment of the pulsatile strength at a monitoring site; it is calculated by means of pulse oximetry by expressing the pulsatile signal as a percentage of the non pulsatile signal by a specialized probe, both of which are derived from the amount of infrared light absorbed.PI can provide useful information about the peripheral perfusion status of the patients and works as an index for sympathetic stimulation. Recent study suggested that PI could be used as an early and sensitive indicator to assess the development of sympathectomy induced by brachial plexus block in conscious adults; it is more sensitive than other parameters such as changes of skin temperature gradients or mean arterial pressure (MAP)

Official Title
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Validation of Peripheral Perfusion Index in Predicting Successful Supraclavicular Brachial Plexus Block for Upper Extremity Procedures in Children.

Conditions
-----------------
Pediatrics, Anesthesia, Local

Participation Criteria
=================
Eligibility Criteria
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Inclusion Criteria: Age group: (3-14) years old. ASA class I-II Exclusion Criteria: Patients with age below 3 year or older than 14 years. Parent refusal. Patients with apparent infection at site of needle insertion. Patients with any coagulation disorder. Patients with known neuropathy or brachial plexus injury. Patients with any cardiac, hepatic, renal or neurological disease

Ages Eligible for Study
-----------------
Minimum Age: 3 Years
Maximum Age: 14 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Perfusion index | The sensitivity of perfusion index in predicting success of supraclavicular brachial plexus block in pediatric patients. | Intraoperative | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Temperature | The sensitivity of temperature change in predicting success of supraclavicular brachial plexus block in pediatric patients. | Intraoperative |
Analyzing the Factors in Ulcerative Colitis Patients' Clinical Trial Experiences

Study Overview
=================
Brief Summary
-----------------
Taking part in clinical trials usually favors a particular demographic group. But there is limited research available to explain what trial attributes affect the completion of these specific demographic groups. This study will admit a wide range of data on the clinical trial experience of Ulcerative Colitis patients to determine which factors prevail in limiting a patient's ability to join or finish a trial. It will also try to analyze data from the perspective of different demographic groups to check for recurring trends which might yield insights for the sake of future Ulcerative Colitis patients.

Official Title
-----------------
An Evaluation of Clinical Study Experiences of Patients With Ulcerative Colitis

Conditions
-----------------
Ulcerative Colitis

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patient is at least 18 years of age Diagnosis of Ulcerative Colitis Ability to understand the study procedures, benefits and risks, and sign a written informed consent document. Exclusion Criteria: Inability to perform regular electronic reporting Women who are pregnant, intend to become pregnant, or are lactating Inability to perform regular electronic reporting

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rate of patients who decide to join in an Ulcerative Colitis clinical trial |  | 3 months | 
| Number of Ulcerative Colitis patients who remain in clinical trial until completion |  | 12 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Ulcerative Colitis