COVID-19 Pandemic Induced Stress and Symptoms

Study Overview
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Brief Summary
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The previous survey of oncology patients at University of California, San Francisco in 2020-2021 found an alarmingly high symptom burden and high levels of stress and loneliness among respondents. This is a follow-up study with the same sample of oncology patients and survivors who participated in the previous study

Detailed Description
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OBJECTIVES: Evaluate for associations among general and disease-specific measures of stress and measures of social isolation and loneliness. Evaluate for associations between general and disease-specific stress and common symptoms associated with cancer and its treatments. Evaluate for associations between social isolation and loneliness and common symptoms associated with cancer and its treatments. Evaluate for associations between social isolation and loneliness and health behaviors and quality of life (QOL) as compared to our last survey. as a baseline. Evaluate for changes in stress, social isolation, loneliness and symptom burden between the two time points. OUTLINE: Patients will be asked to complete self-report questionnaires online. Questionnaires will take approximately 60 minutes to complete. and directed to take rest periods at 20 minute intervals. Participants will be given two weeks to complete the instruments.

Official Title
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COVID-19 Pandemic Induced Stress and Symptoms - Follow-up Study

Conditions
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Stress Reaction, Stress, Emotional, Stress, COVID-19 Pandemic

Intervention / Treatment
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* Other: Questionnaires


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Current/Previous diagnosis of cancer Able to read, write, and understand English Able to complete the study questionnaires on line Able consent to participate. Exclusion Criteria: Participants of our previous COVID survey study who opted out of future research.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Prior oncology participants<br>Oncology patients at University of California, San Francisco who participated in the previous study which evaluated the additional stressors imposed by COVID-19 (i.e., social isolation, loneliness) and ongoing general and disease specific stress on the symptom burden of cancer patients and survivors. | Other: Questionnaires<br>* Self-reported quality of life (QOL) measures completed online<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Correlation of scores on perceived stress scale (PSS) and social isolation scale (SIS) | Scores on the Perceived Stress Scale (PSS) from the previous study and this study, along with scores on the Social Isolation Scale (SIS) from the previous study, this study will be compared. The PSS is a 10-item questionnaire which asks participants about feelings and thoughts during the last month. Scores of each item ranging from 0 = Never to 4 = Very Often for a total score range of 0 to 40. Scores are obtained by reversing responses (e.g., 0 = 4, 1 = 3, 2 = 2, 3 = 1 & 4 = 0) to 4 of the 10 positively stated items and scores are calculated by summing the total. Higher scores indicate higher degree of perceived stress. The Social Isolation Scale (SIS) is a measure used to assess an individual's tendency to isolate themselves from social situations. Scores on this scale are distributed with a mean of 15.0 and a standard deviation of 4.5. | 2 days | 
| Correlation of scores on the perceived stress scale (PSS) and loneliness scale | Scores on the Perceived Stress Scale (PSS) from the previous study and this study, along with scores on the University of California, Los Angeles (UCLA) Loneliness Scale from the previous study, and this study will be compared. The PSS is a 10-item questionnaire which asks participants about feelings and thoughts during the last month. Scores of each item ranging from 0 = Never to 4 = Very Often for a total score range of 0 to 40. Scores are obtained by reversing responses (e.g., 0 = 4, 1 = 3, 2 = 2, 3 = 1 & 4 = 0) to 4 of the 10 positively stated items and scores are calculated by summing the total. Higher scores indicate higher degree of perceived stress. The 3-item UCLA loneliness scale is a 3-item scale used for measuring loneliness with scores ranging from 1='Hardly ever to 3=Often. Scores are summed to generate a total score with higher scores indicating a higher degree of loneliness. | 2 days | 
| Correlation of scores on the perceived stress scale (PSS) and symptom severity scores | Scores on the PSS from the previous study and this study, along with scores on Memorial Symptom Assessment Scale (MSAS) from the previous study, and this study will be compared. The PSS is a 10-item questionnaire which asks participants about feelings and thoughts during the last month. Scores of each item ranging from 0 = Never to 4 = Very Often for a total score range of 0 to 40. Scores are obtained by reversing responses (e.g., 0 = 4, 1 = 3, 2 = 2, 3 = 1 & 4 = 0) to 4 of the 10 positively stated items and scores are calculated by summing the total. Higher scores indicate higher degree of perceived stress. The MSAS is used to assess common physical symptoms experienced by persons with cancer. The values for severity and frequency measurements are 1='slight' or 'rarely' and 4= 'very severe'/'almost constantly' .Higher values indicate a greater number of symptoms. | 2 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Follow-up Study