linjc16/ctgov huggingface dataset:
Correlation of SpO2/FIO2 Ratio With PaO2/FIO2 Ratio in ARDS Patients in the ICU of H. Adam Malik Hospital

Study Overview
=================
Brief Summary
-----------------
This study to apprehend the relation of SpO2/FiO2 to PaO2/FiO2 in ARDS patients.

Detailed Description
-----------------
Acute Respiratory Distress Syndrome (ARDS) is a life-threatening condition that requires immediate treatment. The measurement of the PaO2/FiO2 (P/F) ratio is the main choice for assessing the severity of ARDS with an invasive method that requires arterial blood gas (ABG) analysis. This study was conducted to determine the relationship between the SpO2/FiO2 ratio and the PaO2/FiO2 ratio in ARDS patients at HAM General Hospital. This observational study used a cross-sectional research method with the total sample of 29 intubated ICU patients diagnosed with ARDS. Patients with congestive heart failure, anemia, and systolic blood pressure <90 mmHg were excluded from the study. The results of this study showed a positive correlation between the PaO2/FiO2 and SpO2/FiO2 ratios with a correlation coefficient of 0.955 and a p-value of 0.001. There was a relationship between the S/F ratio and the P/F ratio in assessing the severity of ARDS with a p-value of <0.05. This study shows that the SpO2/FiO2 (S/F) ratio has a good correlation with the PaO2/FiO2 (P/F) ratio in patients with ARDS, so it can be used as a predictor of ARDS and can be beneficial in clinical practice. It should be noted that the SpO2/FiO2 ratio has several factors that can affect its accuracy, so careful assessment is needed.

Official Title
-----------------
Correlation of SpO2/FIO2 Ration With PaO2/FIO2 Ratio in Acute Respiratory Distress Syndrome (ARDS) Patients in the ICU of H. Adam Malik Hospital

Conditions
-----------------
Ards

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: ARDS patient intubarted patient Exclusion Criteria: Cardiac congenital disorder

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Correlation of SpO2/FIO2 Ratio with PaO2/FIO2 Ratio in Acute Respiratory Distress Syndrome (ARDS) Patiens in the ICU of H. Adam Malik Hospital | ICU patients | June - August 2023 |
Learning Skills in Shoulder Dystocia Delivery Using Simulator Models

Study Overview
=================
Brief Summary
-----------------
Learning skills on shoulder dystocia on doctor and midwife

Detailed Description
-----------------
Active learning on mannequin for shoulder dystocia deliveries on doctor and midwife using role play approach and its effect on clinical practice using questionnaires after first training and 6 months training

Official Title
-----------------
Shoulder Dystocia Delivery and Learning Skills on Mannequin

Conditions
-----------------
Shoulder Dystocia - Delivered, Birth Disorder

Intervention / Treatment
-----------------
* Other: modification of clinical approach in clinical practice at time 0
* Other: modification of clinical approach in clinical practice at 6 months


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: residents and specialists in obstetrics and gynecology midwives Exclusion Criteria: none
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| time 0 and 6 months answers<br>questionnaire answers after first training and after re-training on shoulder dystocia model | Other: modification of clinical approach in clinical practice at time 0<br>* evaluation of modification in clinical approach after training<br>* Other names: questionnaire for evaluation of modification in clinical approach;Other: modification of clinical approach in clinical practice at 6 months<br>* evaluation of modification in clinical approach after retraining<br>* Other names: questionnaire for evaluation of modification in clinical approach;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Management of SD | incidence of personal management of SD and fetal and neonatal outcomes in previous experiences and in successive | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Clinical approach in labor ward in identification and management of SD (with previous SD) | modification in approach if previous experience occurred | 6 months | 
| Clinical approach in labor ward in identification and management of SD (without previous SD) | modification in approach without previous experience | 6 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
emergency delivery, Shoulder dystocia, mannequin
Anergia-anhedonia by Lithium-induced Phosphorus Diabetes

Study Overview
=================
Brief Summary
-----------------
Lithium (Li+) is prescribed to 1‰ of the French population (  60,000 patients). More than half of patients describe subjective symptoms linked to Li+ (SSL) similar to those of chronic fatigue syndrome: muscle weakness, fatigability, cognitive disorders, emotional blunting. SSL are the 2nd cause of stopping Li+ (28%), just behind kidney problems (30%). In animals, the administration of lithium (Li+) increases the urinary excretion of phosphate (Pi) by 6, inducing phosphate diabetes (DPi). However, idiopathic forms of DPi explain up to 10-15% of chronic fatigue syndromes and these disappear when supplementing with Pi (± vitamin D). In humans, the introduction of Li+ leads to a reduction in serum phosphate but we have not found any publication on the possible induction of DPi or on a possible link between DPi and SSL. However, the dosages necessary to detect a DPi are carried out during the annual follow-up assessment of patients on Li+. All you have to do is calculate the standardized maximum reabsorption rate of Pi (TmPi) to make the diagnosis! Finally, if the patients presenting with DPi turn out to be the same as those who complain of SSL, we can imagine that correcting the first by simple supplementation with Pi (± vitamin D) could provide relief.

Detailed Description
-----------------
The aim of the study is to determine the prevalence of hypophosphatemia, DPi and SSL in a population of ambulatory patients controlled on Li+ (> 6 months).

Official Title
-----------------
Anergia-anhedonia by Lithium-induced Phosphorus Diabetes

Conditions
-----------------
Mood Disorders

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Major subject (≥ 18 years old) Man or woman Subject balanced on Li+ (> 6 months, regardless of the underlying pathology). Outpatient monitoring by one of the members of CEDRA (Alsace expert center for resistant depression). Subject not opposing, after information, the reuse of their data for the purposes of this research Exclusion Criteria: Subject having expressed opposition to participating in the study Subject under judicial protection Subject under guardianship or curatorship

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prevalence of hypophosphatemia, DPi and SSL at the population level. | The prevalence is determined retrospectively on a population balanced on lithium (Li+) for more than 6 months. | from 6 months after lithium treatment (Li+) | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Diabetes, Phosphate, Anergia-anhedonia, Lithium (Li+), Mood Disorders
Provide Pre-approval Single Patient Expanded Access (Compassionate Use) of Etrasimod for Patients.

Study Overview
=================
Brief Summary
-----------------
Provide pre-approval single patient Expanded Access (Compassionate Use) of Etrasimod for patients.

Detailed Description
-----------------
In Expanded Access, treating physicians are the Sponsors. Expanded Access requests from treating physicians may be submitted to www.pfizercares.com. Availability will depend on location and country.

Conditions
-----------------
Colitis, Ulcerative

Intervention / Treatment
-----------------
* Drug: Etrasimod


Participation Criteria
=================
Eligibility Criteria
-----------------
Patient must be intolerant, have a contraindication or had inadequate response to at least 3 therapies available for Ulcerative Colitis (UC) in this country or provide a rationale of why therapy was not used.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: Etrasimod|tablets|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Ulcerative Colitis
Fecal Continence Outcomes and Quality of Life After Excision of Sacrococcygeal Teratoma (Retrospective Study)

Study Overview
=================
Brief Summary
-----------------
Sacrococcygeal teratoma is one of the most common tumors that occur in the neonatal period. It presents either as a mass protruding from the sacrococcygeal region or as a pelviabdominal mass according to the type. Surgical excision is the main treatment, most masses are benign, however some are malignant and require radiotherapy or chemotherapy. Complications may occur due to pressure resulting from the tumor growth in the fetal period, or due to damage to important near tissues during surgical excision. Postoperative complications may be urinary as neurogenic bladder, Lower gastrointestinal as constipation, soiling or incontinence. In this work we study the outcomes of fecal continence through a questionnaire and its effect on the quality of life of the affected children.

Official Title
-----------------
Fecal Continence Outcomes and Quality of Life After Excision of Sacrococcygeal Teratma (Retrospective Study)

Conditions
-----------------
Sacrococcygeal Teratoma

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: all patients with sacrococcygeal teratoma operated after july 2010 and older than 3 years old. Exclusion Criteria: Patients lost to follow up before 6 months after surgery. Patients with Currarino triad.

Ages Eligible for Study
-----------------
Minimum Age: 3 Years
Maximum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Fecal continence | Measured by Rintala continence score | 6 months |
Evaluation of Digit Tip and Split Skin Donor Site Transcriptome

Study Overview
=================
Brief Summary
-----------------
Regrowth of amputated fingertips presents a unique regenerative healing process in mammals, with subcutaneous volume regrowth, restoration of the dactylogram, and suppression of scar formation. In addition, wound healing from split-thickness donor sites shows almost scar-free healing. Transcriptome analysis is necessary to better understand the specific healing mechanisms of these two wound entities. Since no data are available to date, this study aims to fill the gap.

Detailed Description
-----------------
Regrowth of amputated fingertips presents a unique regenerative healing process in mammals, with subcutaneous volume regrowth, restoration of the dactylogram, and suppression of scar formation. In addition, wound healing from split-thickness donor sites shows almost scar-free healing. Transcriptome analysis is necessary to better understand the specific healing mechanisms of these two wound entities. Since no data are available to date, this study aims to fill the gap.

Official Title
-----------------
Evaluation of Digit Tip and Split Skin Donor Site Transcriptome

Conditions
-----------------
Digit Tip Wound, Split Skin Donor Site

Intervention / Treatment
-----------------
* Other: Digit Tip Wound
* Other: Split Skin Donor Site Wound


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Digit Tip Wound: Wound Exudate from healthy patients: Consent-capable patients ≥18 years of age with clean Digit Tip Wound Split Skin Donor Site Wound: Wound Exudate from healthy patients: Consent-capable patients ≥18 years of age with clean Split Skin Donor Site Wound Exclusion Criteria: Inflammation Borderline Infectious Disease

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Digit Tip Wound<br>Experimental Wound Exudate from Digit Tip Wounds | Other: Digit Tip Wound<br>* Digit Tip Wound Exudate Sample Collected while Dressing Change<br>|
| Split Skin Donor Site Wound<br>Active Comparator Wound Exudate from Split Skin Donor Site Wound | Other: Split Skin Donor Site Wound<br>* Split Skin Donor Site Wound Exudate Sample while Dressing Change<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Differences in RNA-Expression pattern | Differences in RNA-Expression pattern between Digit Tip Wound and Split Skin Donor Site Wound | 5 Weeks | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Digit Tip, Split Skin Donor Site, Transcriptome
Effect of Maternal Age and BMI on Induction of Labor Using Oral Misoprostol in Late-term Pregnancies: a Retrospective Cross-sectional Study

Study Overview
=================
Brief Summary
-----------------
To evaluate the effect of maternal age and body mass index (BMI) on oral misoprostol induction of labor for late-term pregnancies.

Official Title
-----------------
Effect of Maternal Age and BMI on Induction of Labor Using Oral Misoprostol in Late-term Pregnancies: a Retrospective Cross-sectional Study

Conditions
-----------------
Induction of Labor Affected Fetus / Newborn, Pregnancy Late

Intervention / Treatment
-----------------
* Drug: Misoprostol


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Late term pregnancies out of labor, Bishop score < 7 Exclusion Criteria: labor (defined as presence of at least three painful uterine contractions every ten minutes), uterine tachysystole (>5 contractions within 10 minutes for two consecutive 10-minute periods), hypertonic uterus, abnormal CTG, contraindications to vaginal delivery (fetal malpresentation such as breech presentation or transverse situation, fetal macrosomia, abnormally implanted placenta, active genital herpes infection, cervical cancer), patients with parity > 4, medical contraindication to misoprostol (asthma, glaucoma), women with previous hysterotomies.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 50 Years

Sexes Eligible for Study
-----------------
Female

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: Misoprostol|Oral misoprostol for induction of labor in late term pregnancies|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Safety and tolerability of misoprostol for induction of labor | Efficacy induction of labor for late term pregnancies according to age and BMI | 290 days of pregnancy | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Late-term pregnancy, body mass index, age, oral misoprostol, cervical ripening, induction of labor
Primary Cesarean Section in Primigravida and Muligravida in Sohag and Al Balyana Cities

Study Overview
=================
Brief Summary
-----------------
cesarean section and vaginal delivery are two methods of delivery, cesarean section somtimes indicated for obstetrical reason but primary cesarean section especially in primigravida might have a preference of the mode of delivery

Official Title
-----------------
Primary Cesarean Section in Primigravida and Muligravida in Sohag and Al Balyana Cities

Conditions
-----------------
Primary Cesarean Section

Intervention / Treatment
-----------------
* Other: rate of cesarean section


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: all primigravida with gestational age more than 28 weeks and above who have come for delivery multigravida upto gravida 4 with gestational age more than 28 weeks and above who has had one previous viable vaginal delivery women between 18 and 45 years Exclusion Criteria: primigravida women <28 weeks multigravida <28 weeks patient having previous history of myomectomy or hystrotomy gravida 5 and more

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
-----------------
Female

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| primigravida<br> | Other: rate of cesarean section<br>* rate of primary cesarean section in primigravida and multigravida<br>|
| multigravida<br> | Other: rate of cesarean section<br>* rate of primary cesarean section in primigravida and multigravida<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| rate | rate of primary cesarean section | 6 months |
Early Versus Late Laparoscopic Exploration of Common Bile Duct After Failure of Extraction of Common Bile Duct Stones by ERCP

Study Overview
=================
Brief Summary
-----------------
The goal of this work is to assess the best time to perform LC combined with LCBD exploration and the feasibility and safety of such procedure in patients with combined GBS and CBDS after failure of ERCP extraction of CBD stones .

Official Title
-----------------
Early Versus Late Laparoscopic Exploration of Common Bile Duct After Failure of Extraction of Common Bile Duct Stones by ERCP

Conditions
-----------------
Common Bile Duct Calculi

Intervention / Treatment
-----------------
* Device: laparoscopy


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: All patients that presented with calcular obstructive jaundice 2ry to CBD stones. Failed of extraction of common bile duct stone by ERCP. Exclusion Criteria: patients presented by cholangitis. patients presented by acute pancreatitis. Patients that developed post ERCP pancreatitis ,bleeding , perforation. history of previous biliary surgery rather than cholecystectomy. history of major upper abdominal surgery. pregnant females. patients with liverchirosis, abdominal malignancy , and those unfit for surgery.
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Early laparoscopic exploration of common bile duct<br>Early laparoscopic exploration of common bile duct after failure of extraction of common bile duct stones by ERCP | Device: laparoscopy<br>* laparoscopic exploration of common bile duct<br>|
| Late laparoscopic exploration of common bile duct<br>late laparoscopic exploration of common bile duct after failure of extraction of common bile duct stones by ERCP | Device: laparoscopy<br>* laparoscopic exploration of common bile duct<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| intraoperative complications | Assess the operative time in hours intraoperative blood loss in millilitres intraoperative organ injury (yes or no) conversion to open surgery (yes or no) | Baseline | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| postoperative complications | Postoperative bleeding in millilitres biliary leakage in millilitres missed stone (yes or no) recumbency complications which are monitored for 30 days postoperatively. 5.Overall length of hospital stay and if Intensive Care Unit (ICU) stay needed will also be recorded in days. | Baseline |
Caudal Block & Hip Fracture Surgery in Anticoagulated Patient

Study Overview
=================
Brief Summary
-----------------
Hip fractures are common in elderly patients, and require surgery. Many elderly patients take anticoagulants for vasculopathy treatment. Anticoagulation precludes the use of neuraxial anesthesia because of the risk of epidural bleeding. Caudal anesthesia may be a safe and effective technique in anticoagulated emergency surgical patients. Quantitative analysis of prospective clinical data. Evaluation of caudal anesthesia efficacy for hip fracture surgery. Analysis of perioperative outcome, and postoperative course.

Detailed Description
-----------------
Hip or femoral neck fractures are common in elderly patients. These fractures require surgical repair. Many elderly patients take regular anticoagulant therapy for vasculopathy. Anticoagulation precludes the use of spinal or epidural anesthesia because of the risk of epidural bleeding. Caudal anesthesia is another form of neuraxial anesthesia that may be safe and effective for hip fracture surgery in anticoagulated elderly patients. Quantitative analysis of prospective clinical data. It is an evaluation of caudal anesthesia efficacy for hip fracture surgery. This is an analysis of intraoperative analgesia, perioperative outcome, postoperative course, and complications.

Official Title
-----------------
Caudal Anesthesia for Surgical Repair of Fractured Hip or Femoral-neck in Anticoagulated Patients

Conditions
-----------------
Hip Fractures, Anticoagulants and Bleeding Disorders

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with fractured hip or femoral neck who undergo surgical repair Exclusion Criteria: Patients who refuse surgical repair

Ages Eligible for Study
-----------------
Minimum Age: 50 Years
Maximum Age: 99 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain score, objective measurement using the validated Numeric Pain Rating scale | Pain score, using the Numeric Pain Rating scale of 0 to 10, low scores indicate less pain, high scores indicate worse pain | 1 month | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Caudal anesthesia