Effects of Aerobic Training Program On Liver Functions

Study Overview
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Brief Summary
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The liver plays a central role in energy exchange, protein synthesis as well as the elimination of waste products from the body. The optimal functioning of the liver is essential for athletic performance. It becomes necessary to maintain the enzymes of the liver at an optimal level so that liver cells can be protected from inflammation or damage. This paper investigated the effects of a twelve-week aerobic exercise program on the liver function of adult athletes. A total of thirty (30) healthy male athletes aged 21 to 24 were recruited for this study and kept in two equal groups. The control group was kept under rigorous supervision and did not participate in any special activities. The experiment group was well-versed in their assigned training program and solely performed the experimental procedure for twelve (12) weeks. Evaluation of all patients in both experimental and control groups was carried out before and after the treatment program by measuring the levels of (Alkaline phosphate, AST/SGOT, ALT/SGPT, Bilirubin Total/indirect/direct, Albumin, Globulin, and Total protein) respectively using standard methods by collecting blood samples, 5 mls each of baseline into lithium heparin containers for estimation of above biochemical parameters at the pathology laboratory accredited by National Accreditation Board for Testing and Calibration Laboratories accredited (NABL, India).

Official Title
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Effects of an Aerobic Training Program on Liver Functions in Male Athletes - a Randomized Controlled Trial

Conditions
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Liver Functions

Intervention / Treatment
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* Other: Aerobic training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Male Age: 21-24 years Healthy Athletes Exclusion Criteria: history of severe illness, surgery, or damage to liver, fatty liver disease, cirrhosis, blood infections, neuromuscular illnesses, or the presence of any disorders such as fever, high blood pressure, high blood sugar

Ages Eligible for Study
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Minimum Age: 21 Years
Maximum Age: 24 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Experimental Group<br>Aerobic training program was performed by participants. | Other: Aerobic training<br>* Exercises on a treadmill at different speeds and inclination were performed.<br>|
| No Intervention: Control group<br>No intervention was performed by the participants. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bilirubin-Total | Blood level of Bilirubin-Total was measured. | 12 weeks. | 
| Serum aspartate aminotransferase/serum glutamic-oxaloacetic transaminase (AST/SGOT) | Blood level of Serum AST/SGOT was measured. | 12 weeks. | 
| Serum alanine transaminase/Serum Glutamic Pyruvic Transaminase (ALT/SGPT) | Blood level of Serum ALT/SGPT was measured. | 12 weeks. | 
| Alkaline Phosphatase | Blood level of Alkaline Phosphatase was measured. | 12 weeks. | 
| Protein-Total | Blood level of Protein-Total was measured. | 12 weeks. | 
| Albumin | Blood level of Albumin was measured. | 12 weeks. | 
| Globulin | Blood level of Globulin was measured. | 12 weeks. | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Fatty liver, Physical activity, Treadmill, Exercises