Predictors of Postoperative Atrial Fibrillation After CABG

Study Overview
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Brief Summary
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This observational study aims to identify the determinants or predictors of postoperative atrial fibrillation (POAF) in patients who have undergone coronary artery bypass grafting (CABG). The study will compare two cohorts: patients who developed POAF and those who did not (non-POAF), with the aim of improving postoperative care, reducing complications, and refining patient risk stratification.

Detailed Description
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Demographics (age, sex, ethnicity), lifestyle factors (smoking, alcohol, physical activity), and medical history (diabetes, hypertension, prior heart diseases) will be recorded. Surgical procedure details (number of grafts, use of intraoperative devices), anesthesia, and medications administered. Levels of inflammatory markers, cardiac-specific markers, and other relevant biomarkers at baseline and postoperatively. Other complications besides POAF, hospital length of stay, ICU admission, readmission rate, and mortality will also be monitored.

Official Title
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A Comprehensive Observational Study on the Determinants of Postoperative Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass Grafting

Conditions
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Coronary Artery Disease, Atrial Fibrillation New Onset

Intervention / Treatment
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* Procedure: CABG


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adults aged 18 years or older. Patients who underwent CABG. Exclusion Criteria: Patients with a history of preoperative atrial fibrillation or other significant arrhythmias. Patients who underwent other concurrent cardiac procedures (e.g., valve surgery) in addition to CABG. Patients who cannot provide informed consent or lack adequate follow-up information.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| POAF<br>This group will consist of patients who have developed postoperative atrillary fibrillation (POAF) after undergoing coronary artery bypass grafting (CABG). | Procedure: CABG<br>* All participants in the study will undergo the standard procedure of CABG. Continuous electrocardiogram monitoring and electrocardiography were used to identify the cardiac rhythm.<br>|
| Non-POAF<br>This group will consist of patients who have not developed postoperative atrillary fibrillation (POAF) after undergoing coronary artery bypass grafting (CABG). | Procedure: CABG<br>* All participants in the study will undergo the standard procedure of CABG. Continuous electrocardiogram monitoring and electrocardiography were used to identify the cardiac rhythm.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of POAF | This will be determined based on electrocardiograms (ECG) and/or relevant medical records, within 30 days post-CABG. | During hospital stay, up to 30 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Hospital length of stay |  | During hospital stay, up to 30 days | 
| ICU admission time |  | During hospital stay, up to 30 days | 
| Number of participants with Stroke |  | During hospital stay, up to 30 days | 
| Mortality |  | During hospital stay, up to 30 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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coronary artery bypass grafting, postoperative atrial fibrillation