Long COVID Symptoms in SARS-CoV-2-positive Children in China

Study Overview
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Brief Summary
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The goal of this observational study is to learn about in children aged 6-18 years, after the acute phase of SARS-CoV-2 infection, the COVID symptoms or Long COVID symptoms to impact their daily activities. We aimed to investigate the prevalence of long-lasting symptoms, the duration and intensity of symptoms, quality of life, number of sick days or absences from school, and psychological and social outcomes. The participants will be asked to fill in Long COVID symptom burden questionnaires who had been infected with SARS-CoV-2 as self-reported PRC test or antigen test positive.

Detailed Description
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The goal of this observational study is to learn about in children aged 6-18 years, after the acute phase of SARS-CoV-2 infection, the COVID symptoms or Long COVID symptoms to impact their daily activities. We aimed to investigate the prevalence of long-lasting symptoms, the duration and intensity of symptoms, quality of life, number of sick days or absences from school, and psychological and social outcomes. The participants will be asked to fill in SBQ-Long COVID symptom burden survey questionnaires who had been infected with SARS-CoV-2 as self-reported PRC test or antigen test positive. The survey questionnaires will be filled every two weeks after the participants have been tested SARS-CoV-2 positive.

Official Title
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Long COVID Symptoms in SARS-CoV-2-positive Children Aged 6-18 Years in China: a Consequential Observation Study

Conditions
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Symptoms and Signs

Intervention / Treatment
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* Other: SBQ-LC survey


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: infected with SARS-CoV-2 as self-reported PRC test or antigen test positive or have symptoms, but without Covid-19 test. Exclusion Criteria: aged below 6 years or above 18 years

Ages Eligible for Study
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Minimum Age: 7 Years
Maximum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Group 1 aged 7-12 years<br>Group 1 will mainly be primary school students from grade 1 to 6. | Other: SBQ-LC survey<br>* Symptom burden questionnaires of Long COVID<br>|
| Group 2 aged 13-15 years<br>Group 2 will mainly be middle school students from grade 13 to 15. | Other: SBQ-LC survey<br>* Symptom burden questionnaires of Long COVID<br>|
| Group 2 aged 16-18 years<br>Group 3 will mainly be high school students from grade 16 to 18. | Other: SBQ-LC survey<br>* Symptom burden questionnaires of Long COVID<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| long symptoms of SARS-CoV-2 | the prevalence of long-lasting symptoms, the duration and intensity of symptoms | 6 to 12 weeks | 
| absences from school | number of sick days or absences from school, and psychological and social outcomes. | 24 weeks |