Effectiveness of a Cancer Exercise Program

Study Overview
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Brief Summary
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The investigators are examining the impact of an 8-week multi-modal exercise program (resistance and cardiovascular training) delivered 2 times per week on physical function adults (>18 years old) with cancer.

Official Title
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The Impact of an 8-week Exercise Program on Physical Function in Individuals With Cancer

Conditions
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Cancer

Intervention / Treatment
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* Behavioral: Exercise


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adults > 18 diagnosed with cancer Exclusion Criteria: unwilling to come to the on-site clinic for exercise sessions any neuromuscular, cardiovascular, or psychological condition precluding safe exercise unable to read/understand English.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Exercise<br>2 days/week of resistance and cardiovascular exercise for 8-weeks | Behavioral: Exercise<br>* A combination of resistance exercise and cardiovascular exercise (performed 2 days per week for 8-weeks) is tailored to each individual in accordance with their medical/cancer-related history, baseline assessments of physical function, and overall goals. Resistance exercise includes 6-8 exercises targeting major muscle groups. The first week of the program is used to familiarize participants to the exercises of the program, provide coaching on safe and appropriate technique, and identifying initial load for 2 sets of 12 repetitions (equivalent to  65% 1 repetition maximum), with a goal of working towards 4 sets of 8 reps. Additionally, participants are asked to perform 20-30 minutes of moderate-to-vigorous aerobic activity (approximately 60-85% age-predicted heart rate maximum) via walking, jogging, or cycling each session.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bellarmine Norton Assessment Tool (2-minute Step Test) | 2-minute Step Test: Number of times an individuals' knee reaches a predetermined heigh during a 2-minute period of marching | 0 and 8-weeks | 
| Bellarmine Norton Assessment Tool (Timed Arm Curl) | Timed Arm Curl: Number of repetitions an arm curl individuals can complete in 30 seconds) | 0 and 8-weeks | 
| Bellarmine Norton Assessment Tool (30 second Chair Stand) | Chair Stand: Number of times participants can stand from a sitting position and return to sitting in 30 seconds | 0 and 8-weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Fatigue | The Functional Assessment of Chronic Illness Therapy (FACIT) Fatigue Scale: The FACIT-Fatigue scale is a 13-item scale that will be used to assess cancer-related fatigue. The FACIT-Fatigue scale is scored on a 0-4 response scale from 0 = not at all to 4 very much, regarding items related to fatigue and energy in the past 7 days. Lower score indicates greater fatigue | 0 and 8-weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Exercise