Observe the Effect of Wheatgrass and Tulsi Formulation or Individuals Taken With Other Allopathic Drugs

Study Overview
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Brief Summary
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Antioxidant qualities have been attributed to wheatgrass and tulsi formulation. Free radicals are unstable molecules created by the body during metabolism and exposure to environmental pollutants. Antioxidants are chemicals that can help stop or reduce cell damage caused by these unstable molecules. Oxidative stress, which is brought on by free radicals, has been connected to a number of health issues, including chronic inflammation, cardiovascular disease, cancer, and ageing. Wheatgrass is a rich source of vitamins, minerals, amino acids, and chlorophyll, which have been shown to have antioxidant and anti-inflammatory effects. Tulsi, also known as holy basil, is an herb that has been used in Ayurvedic medicine for centuries and has been found to have antioxidant, anti-inflammatory, and immunomodulatory properties. Several studies have investigated the antioxidant properties of wheatgrass and tulsi formulation. For instance, a study published in the Journal of Food Science and Technology in 2015 found that wheatgrass extract had significant antioxidant activity, as measured by its ability to scavenge free radicals and reduce lipid peroxidation in vitro.

Detailed Description
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Similarly, a study published in the Journal of Ethnopharmacology in 2001 found that tulsi extract had significant antioxidant activity, as measured by its ability to scavenge free radicals and inhibit lipid peroxidation in vitro. Moreover, a study published in the Journal of Medicinal Food in 2011 investigated the antioxidant and anti-inflammatory effects of a combination of wheatgrass and tulsi extracts in rats. The study found that the combination of wheatgrass and tulsi extracts had significant antioxidant and anti-inflammatory effects, as measured by reductions in oxidative stress markers and pro-inflammatory cytokines. Overall, the available evidence suggests that wheatgrass and tulsi formulations may have antioxidant properties, which could potentially help prevent or slow down oxidative stress-related health problems. However, more research is needed to confirm these findings and determine the optimal dosage and duration of wheatgrass and tulsi formulation use for maximum antioxidant benefits. There are several studies that suggest wheatgrass and tulsi formulations have antioxidant properties. A study evaluated the immunomodulatory and antioxidant properties of a traditional formulation containing Tulsi, ginger, and wheatgrass. Another study investigated the antioxidant potential of anthocyanin extracts from colored wheat flour and wheat-grass juice. Additionally, a synergistic effect of conventional medicinal herbs against oxidative stress was observed in another study that included tulsi and wheatgrass. While a study compared the chemical composition, sensory, phenolic, and antioxidant properties of juices from different wheatgrass and turfgrass species, it did not specifically investigate a formulation with tulsi. Another study found that vitamin C is present in wheatgrass which is also an antioxidant.

Official Title
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Observation of Wheatgrass and Tulsi Formulation or Its Effect With Allopathic Drugs

Conditions
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Blood Pressure, High, Blood Sugar; High, Weight, Birth, Smoking

Intervention / Treatment
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* Other: Observation study


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients who are having a chronic disease and taking formulation wheat grass and tulsi. Patients who are taking wheatgrass and tulsi separately. Patients who are taking wheatgrass, tulsi and regular medicine. - Exclusion Criteria: Patients below 30 years. Patients who are having a chronic disease but not using formulations of wheatgrass and tulsi. Patients who are not taking wheatgrass and tulsi separately.

Ages Eligible for Study
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Minimum Age: 30 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| With Wheatgrass, tulsi formulation<br>People using Wheatgrass and Tulsi formulation or individual | Other: Observation study<br>* Looking to find the role of wheatgrass and tulsi give separately or with allopathic drug<br>|
| With Wheatgrass, tulsi formulation and allopathic drugs<br>People using Wheatgrass and Tulsi formulations or individuals with chronic disease medicine. | Other: Observation study<br>* Looking to find the role of wheatgrass and tulsi give separately or with allopathic drug<br>|
| Same age group not using any medication<br> | Other: Observation study<br>* Looking to find the role of wheatgrass and tulsi give separately or with allopathic drug<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Effect of wheat grass and tulsi in combination on blood pressure | Blood Pressure measured in mmHg every four week. | Every four week till 6 months | 
| Effect of wheat grass and tulsi in combination on blood sugar | Blood Sugar measured in mmol/L every four week | Every four week till 6 months | 
| Effect of wheat grass and tulsi in combination on weight | Weight is measure in Kg every four week. | Every four week till 6 months | 
| Effect of wheat grass and tulsi in combination on smoking | questionnaire assesment for Smoking habits | Every four week till 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Effect of wheat grass and tulsi separately on blood pressure | Blood Pressure measured in mmHg every four week. | Every four week till 6 months | 
| Effect of wheat grass and tulsi separately on blood sugar | Blood Sugar measured in mmol/L every four week. | Every four week till 6 months | 
| Effect of wheat grass and tulsi separately on weight | Weight is measure in Kg every four week. | Every four week till 6 months | 
| Effect of wheat grass and tulsi separately on smoking | questionnaire assesment for Smoking habits | Every four week till 6 months | 
| Effect of wheat grass, tulsi and allopathic drug on blood pressure | Blood Pressure measured in mmHg every four week. | Every four week till 6 months | 
| Effect of wheat grass, tulsi and allopathic drug on blood sugar | Blood Sugar measured in mmol/L every four week. | Every four week till 6 months | 
| Effect of wheat grass, tulsi and allopathic drug on weight | Weight is measure in Kg every four week. | Every four week till 6 months | 
| Effect of wheat grass, tulsi and allopathic drug on smoking | questionnaire assesment for Smoking habits | Every four week till 6 months |