the Effect of Speed Dependent Treadmill Training on Dual Task Performance in Patient With Parkinson's Disease.

Study Overview
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Brief Summary
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The aim of this randomized clinical trail is to identify the impact of treadmill training on walking while doing dual task in patients with Parkinson's disease. By improving walking speed, bradykinesia would be reduced in Parkinson's patients. So, the findings of this study can help in formulation of future guidelines for management of Parkinson's that will help the clinicians to treat such patients in more efficient way.

Detailed Description
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A RCT that investigated the effect of Treadmill training and physiotherapy in patient with PD using dual tasking as outcome measure.105 Parkinson's disease (PD) patients; these are the subject who received treadmill training and physiotherapy for 14 days. Both intervention helps the patients to enhance the dual task gait velocity. A study is to identify the effects of incremental speed-dependent treadmill training on postural instability and fear of falling in Parkinson's disease to observe the postural stability by incremental speed dependent treadmill training. 54 patient of Parkinson's disease (PD) was randomly allocated in to experimental and control group. 8-week training program was conducted including stretching, Range of motion exercises (ROM), and treadmill training. Walking distance of the training group was gradually increased after 16 training sessions. The training group's scores on the Berg Balance Test, Dynamic Gait Index, and Falls Efficacy Scale dramatically improved after the training program. While the control group, shows no significant improvement in outcome measurements. Specific exercise regimens, such as incremental speed-dependent treadmill training, may increase mobility and minimize fear of fall in-patient with Parkinson's disease. GAP:The study's relatively small sample size is one of its limitations. There is least work done on speed dependent treadmill training and its effect on dual task performance in-patient with Parkinson's disease. More research is require, to compare various treatment options with incremental speed-dependent treadmill training for Parkinson's disease patients.

Official Title
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To Understand the Effect of Speed Dependent Treadmill Training on Dual Task Performance in Patient With Parkinson's Disease.

Conditions
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Parkinson Disease

Intervention / Treatment
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* Device: speed dependent treadmill training on moderate speed
* Device: speed dependent treadmill training on slow speed


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Able to walk on treadmill for 20 min Cognitively able to perform required task Hoehn and yarn disease stage between I to III. Exclusion Criteria: Gait impairment Cardiac impairment Dementia History of fall Severe Freezing episodes Camptocormia (axial deformity) Central or peripheral paresis Score less than 20 in mini mental scale.

Ages Eligible for Study
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Minimum Age: 30 Years
Maximum Age: 90 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: speed dependent treadmill training on moderate speed<br>speed dependent treadmill training on moderate speed along with strengthening, stretching and range of motion exercises. | Device: speed dependent treadmill training on moderate speed<br>* Experimental group will receive 14 session of speed dependent treadmill training on moderate speed (3 to 6) for 25 minutes along with strengthening, stretching and range of motion exercises.<br>|
| Active Comparator: speed dependent treadmill training on slow speed<br>Speed dependent treadmill training on slow speed along with physiotherapy. | Device: speed dependent treadmill training on slow speed<br>* Control group will receive 14 session of speed dependent treadmill training on slow speed (1 to 2) for 25 min along with physiotherapy.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Unified Parkinson disease rating scale (UPDRS-III) | UPDRS-III is a Gold standered for Parkinson disease. It completely access the body function, activities and participation of Parkinson's patient. It consist of 6 session. We will only use Scale's motor component, which consist of 14 item. Each sign and symptom is rated on a 5-point scale (ranging from 0 to 4) higher score represent severe impairment. Highest point represent total or maximal disability. | 1 day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| dual task gait speed test | This test use to access the dual-task gait speed. the gait speed will be measured in single task first, and then in dual task before and after the treatment. | 1 day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Treadmill training, Dual-task performance, Parkinson disease, Physiotherapy