linjc16/ctgov huggingface dataset:
Impact of Mandibular Overdenture Base Construction Techniques on Assessment of Occlusion

Study Overview
=================
Brief Summary
-----------------
This within patient study will be conducted to compare between two different construction techniques (CAD-CAM Milled and Conventional techniques) of 4-implant-assisted complete mandibular overdenture bases regarding the digital occlusion force balance analysis using the OccluSense

Official Title
-----------------
Impact of Mandibular 4-Implant Overdenture Base Construction Techniques on Assessment of Occlusion With Digital Occlusion Analysis System (Within Patient Study)

Conditions
-----------------
Prosthesis Durability

Intervention / Treatment
-----------------
* Device: CAD/CAM Complete denture


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 1. Free from any systemic diseases that contraindicate dental implantation. 2. Angel's class I maxillo- mandibular relation. 3. Available inter-arch space and sufficient restorative space. 4. Nonsmokers, non-alcoholics. 5. Complaints from their conventional denture Exclusion Criteria: diabetic and heavy smoker patients

Ages Eligible for Study
-----------------
Minimum Age: 40 Years
Maximum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Crossover Assignment
Interventional Model Description: According to the construction technique for the maxillary complete denture and mandibular overdentures, the patients will be classified randomly and equally into two groups. Group I: patients receive maxillary complete denture opposed to four implant-assisted mandibular overdenture constructed with conventional method. Group II: patients receive maxillary complete denture opposed to four implant-assisted mandibular overdenture constructed with CAD/CAM milling.
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Group I: patients receive maxillary complete denture opposed to conventional mandibular overdenture<br> | Device: CAD/CAM Complete denture<br>* four implant-supported CAD/CAM complete overdenture<br>|
| Active Comparator: Group II: patients receive maxillary complete denture opposed CAD/CAM overdenture<br> | Device: CAD/CAM Complete denture<br>* four implant-supported CAD/CAM complete overdenture<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| digital occlusal analysis | occlusion was analyzed by occlusense device | 6 months |
Fat to Lean Mass Ratio and Its Effect on Low Back Pain and Permanent Functional Disability.

Study Overview
=================
Brief Summary
-----------------
The study was conducted for people who suffer from excess fat mass and their age is over 18 years will be calculated with G*power will be used body composition analyzer to calculate the percentage of fat.

Detailed Description
-----------------
Cross-sectional study was applied. Data was collected through a questionnaire (oswestry disability index arabic version). Fat percentage was taken by Body composition analyzer.

Official Title
-----------------
Fat to Lean Mass Ratio and Its Effect on Low Back Pain and Permanent Functional Disability.

Conditions
-----------------
Low Back Pain, Mechanical

Intervention / Treatment
-----------------
* Other: Fat to Lean Mass Ratio


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Excess fat mass Age must be over 18 years. Exclusion Criteria: People under the age of 18. Low back pain not associated with increased fat mass.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 24 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Fat to Lean Mass Ratio|The study will be conducted for people who suffer from excess fat mass and their age is over 18 years. years will be calculated with G power|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Fat to Lean mass ratio | Body composition analyzer will be used to measure the percentage of fat | Immediately after the admission | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Low Back Pain and disability | Oswestry disability index arabic version will be used. | Immediately after the admission |
Effect of Neuromuscular Training Versus Traditional Exercise on Balance and Fall in Geriatric Population With Fall Risk

Study Overview
=================
Brief Summary
-----------------
To determine the effect of neuromuscular training versus traditional exercise on balance and fall in geriatric population with fall risk

Detailed Description
-----------------
neuromuscular training versus traditional exercise for the balance messurement of fall population with geriatric

Official Title
-----------------
Effect of Neuromuscular Training Versus Traditional Exercise on Balance and Fall in Geriatric Population With Fall Risk

Conditions
-----------------
Geriatric

Intervention / Treatment
-----------------
* Diagnostic Test: Neuromuscular Training
* Diagnostic Test: Traditional Exercise


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with balance and fall problem doing physical therapy with an age over 60 years old and willing to participate will be included in the study. Exclusion Criteria: Patient with other serious comorbidities and suffering from heart or kidney disease will not be include or unwilling to participate and those who will aged under 60 years will be excluded from the study

Ages Eligible for Study
-----------------
Minimum Age: 60 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Health Services Research
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Neuromuscular Training<br> | Diagnostic Test: Neuromuscular Training<br>* Neuromuscular Training on Balance and Fall in Geriatric Population With Fall Risk<br>|
| Active Comparator: Traditional Exercise<br> | Diagnostic Test: Traditional Exercise<br>* Traditional Exercise on Balance and Fall in Geriatric Population With Fall Risk<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Berg Balance Scale and Falls Efficiancy Scale international | FES and BFalls Efficiancy Scale international the balance for Geriatric Population With Fall Risk | 6 Month |
Anomalous Aortic Origin of Coronary Artery

Study Overview
=================
Brief Summary
-----------------
This project has several objectives ranging from clinical data analysis to computational simulations as listed below: A) Clinical objectives: Retrospective review of all patients with AAOCA treated surgically and followed medically at the IRCCS Policlinico San Donato aiming to identify risk factors for ischemia or sudden cardiac deaths. Prospective follow-up of all enrolled patients, treated and followed, in adjunct to all the new patients referred aiming to follow across the years any potential rare adverse event (ischemia, angina event, sudden cardiac death). B) Experimental objectives: Retrieve morphological measurements from CT or MRI (de-identified) of the aortic root and the coronary vessels following the previous work of our group. Construct a parametric model of the aortic root defined by population-based morphologic parameters to describe both healthy/diseased population. Run solid mechanics simulation mimicking the movement of the aortic root in order to test configurations at more risk. Reconstruct 3D surfaces representing the coronary vasculature from imaging for automatically perform the parameter estimation and run computational fluid dynamics simulations.

Official Title
-----------------
Anomalous Aortic Origin of Coronary Artery: From Pathophysiology to Risk Stratification Through a Patient Specific Computational Simulation Model

Conditions
-----------------
Anomalous Aortic Origin of the Coronary Artery (AAOCA)

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: All patients (adults and pediatrics) who have been diagnosed with an anomalous aortic origin of any of the coronary arteries (AAOCA) without any other congenital heart disease and diagnosed/referred or followed at the IRCCS Policlinico San Donato. Exclusion Criteria: Patients with other major congenital heart disease with associated coronary artery origin anomalies will be excluded. Patients with anomalous origin of the coronary artery from the pulmonary artery (ALCAPA or ARCAPA) will be excluded. Patients women who are pregnant.
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| ischemia, angina event, sudden cardiac death | 2. Creation of a prospective registry in which will be enrolled all patients already treated and followed in adjunct to all the new patients referred aiming to follow across the years any potential rare adverse event | 10 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| risk factors for ischemia or sudden cardiac deaths | 1. Retrospective review of all patients with AAOCA treated surgically and followed medically at the IRCCS Policlinico San Donato aiming to identify risk factors for ischemia or sudden cardiac deaths. | 10 years |
Osteopontin as a Biomarker in Pancreatitis

Study Overview
=================
Brief Summary
-----------------
In the early phase of pancreatits, factors that can give information about the development of severety are still lacking. In this study patients will be included prospectively upon the diagnosis of pancreatits and clinical as well as labarotory and radiological factors will be sampled. The aim is do identifiy factors that may aid in the risk stratification for development of different severity grades of pancreatitis.

Detailed Description
-----------------
In the early phase of pancreatits, factors that can give information about the development of severety are still lacking. In this study patients will be included prospectively upon the diagnosis of pancreatits and clinical as well as labarotory and radiological factors will be sampled. The aim is do identifiy factors that may aid in the risk stratification for development of different severity grades of pancreatitis. Patients admitted and diagnosed with pancreatitis (according to the Atlanta criteria) will have serial testing of se-osteopontin in addiation to rutine blood work. Computet tomograpy and chest x-ray are mandatory as is blood culture.

Official Title
-----------------
Osteopontin and Other Potential Biomarkers and Factors Important for Prognosis in Pancreatitis

Conditions
-----------------
Pancreatitis

Intervention / Treatment
-----------------
* Other: No intervention, observation


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Diagnosis of pancreatitis Exclusion Criteria: Pregnancy, lactation, unable to understand the study

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Pancreatits<br>Patients with pancreatitis based ont the Atlanta criteria | Other: No intervention, observation<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Se-osteopontin | Se-osteopontin will be measured at admission and on day 2 and 3 of hospital stay. The change over time will be correlated to severety of pancreatitis as classified in the current Atlanta classification. | Within 3 days from diagnosis |
System Accuracy of BGM GL60

Study Overview
=================
Brief Summary
-----------------
This study assesses the system accuracy a blood glucose monitoring systems pursuant to ISO 15197

Detailed Description
-----------------
This study assesses the system accuracy ofthe blood glucose monitoring systems for personal use GL60 as outlined in DIN EN ISO 15197:2015.

Official Title
-----------------
Evaluierung Der Systemgenauigkeit Des Blutglucosemonitoring Systems GL60 gemäß DIN EN ISO 15197:2015

Conditions
-----------------
Diabetes Mellitus

Intervention / Treatment
-----------------
* Diagnostic Test: Glucometer Test


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion criteria: Male or female patients with hypo-, eu- or hyperglycaemia The written informed consent had to be signed The volunteers must be older than 18 years The volunteers have legal capacity and are able to understand meaning, nature and possible consequences of the procedures involved Exclusion criteria: Pregnancy or lactation Acute or chronic diseases with the risk of aggravation by the measure A current constitution that does not allow participating in the study Participation in another study or activity with the blood glucose measuring system evaluated in the present study Application of substances listed in Appendix A of DIN EN ISO 15197:2015

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Subject glucometer measurement<br> | Diagnostic Test: Glucometer Test<br>* measurement of the blood glucose concentration using the blood glucose monitor for personal use<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Analysis of system accuracy based on DIN EN ISO 15197 | Assessment of the analytical measurement performance of the blood glucose monitor | Day 1 |
The Reliability And Validity Of A Smartphone App

Study Overview
=================
Brief Summary
-----------------
The goal of this observational study is to validate a smartphone app called Angulus. The main question it aims to answer is: • Is an Angulus App valid and reliable system for masuring hand and wrist range of motion? Participants will be evaluated by goniometers which is a gold standart for range of motion assessment.

Official Title
-----------------
The Reliability And Validity Of A Smartphone App For Measuring Wrist And Metacarpophalangeal Joint Motion

Conditions
-----------------
Rheumatoid Arthritis, Carpal Tunnel Syndrome

Intervention / Treatment
-----------------
* Diagnostic Test: Angulus


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: a history of previous traumatic hand or wrist injury in the upper extremity, pain in the hand and wrist during evaluation orthopedic, neurologic, or rheumatologic disease Exclusion Criteria: not to understand the command that the therapist give

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Healthy Adults<br> | Diagnostic Test: Angulus<br>* Smartphone app<br>|
| Rheumatoid Arthritis<br> | Diagnostic Test: Angulus<br>* Smartphone app<br>|
| Carpal Tunnel Syndrome<br> | Diagnostic Test: Angulus<br>* Smartphone app<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Range of Motions |  | 15 weeks | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
reliability, validity, range of motion
Evaluation of Mechanical Characteristics of Tendons of Athletes Using Sonography

Study Overview
=================
Brief Summary
-----------------
The investigators analyzed the strain of the rotator cuff tendon of baseball pitchers obtained using ultrasonography and compared the change in peak tendon strain before and after the regular season.

Official Title
-----------------
Evaluation of Mechanical Characteristics and Prevention From Overuse Injury of Tendons of Elite Athletes Using Dynamic Sonography

Conditions
-----------------
Overuse Injury, Rotator Cuff Injuries

Intervention / Treatment
-----------------
* Diagnostic Test: Ultrasonography


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Baseball pitchers in city baseball team Exclusion Criteria: History of shoulder disorder or surgery

Ages Eligible for Study
-----------------
Minimum Age: 21 Years
Maximum Age: 33 Years

Sexes Eligible for Study
-----------------
Male

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: Ultrasonography|Collect shoulder rotator cuff tendon ultrasound image during isotonic motion|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Peak tendon strain | The peak value of tendon strain during the isotonic motion estimated from ultrasound image sequence | Two months |
Evaluation of TaiHao Breast Ultrasound Diagnosis Software RN-CES Descartes

Study Overview
=================
Brief Summary
-----------------
A standard of truth SOT is determined based on the interpretation results of the case data by interpretation experts, and the SOT is compared with the detection results of this program's function for detecting suspected breast cancer (CADe function). Estimate the detectability of the CADe function by comparing.

Official Title
-----------------
Evaluation of TaiHao Breast Ultrasound Diagnosis Software (Plan for Partial Modification of Diagnostic Performance)

Conditions
-----------------
Breast Cancer, Breast Diseases

Intervention / Treatment
-----------------
* Diagnostic Test: Define Standard of Truth (SOT) by Taihao Breast Cancer Diagnostic Software


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Female patients aged 20 to 69, including those with and without breast lesions. Exclusion Criteria: Have a pacemaker or prosthetic valve. A post-surgery follow-up patient.

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 69 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Define Standard of Truth (SOT) by 3 experts<br>Three experts A, B, and C independently define standard of truth (SOT) about 108 cases. | Diagnostic Test: Define Standard of Truth (SOT) by Taihao Breast Cancer Diagnostic Software<br>* TaiHao Breast Cancer Diagnostic Software independently define standard of truth (SOT) about108 cases.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The average performance of the 4 machines, in terms of sensitivity for detecting suspicious breast cancer, is not inferior to Siemens performance. | The average of 4 types of machines (Canon Aplio i800, GE Logiq E10, GE Invenia ABUS, Fuji ARIETTA 60) performance compared to Siemens performance which was submitted to PMDA last time. | 1 week | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The performance of each of the 4 machines, in terms of sensitivity for detecting suspicious breast cancer, is not inferior to Siemens' performance. | Each machine (Canon Aplio i800, GE Logiq E10, GE Invenia ABUS, Fuji ARIETTA 60) performance compared to Siemens performance which was submitted to PMDA last time. | 1 week |
Early Visual Functions in Patients at Risk of Developing Cerebral Visual Impairment. A Pilot Study

Study Overview
=================
Brief Summary
-----------------
The aim of the study is to assess visual function from neonatal age to 36 months of age in infants at risk of visual impairment due to brain lesion or ocular pathology

Official Title
-----------------
Early Visual Functions in Patients at Risk of Developing Cerebral Visual Impairment. A Pilot Study

Conditions
-----------------
Visual Impairment

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age between 34 weeks of post-menstrual age and 36 months of life in children born before 37 weeks gestational age Genetic syndroms Hypoxic Hischemic Encephalopathy Brain malformation Metabolic diseases Ocular pathologies Exclusion Criteria: Patients at low risk of developing neurological outcomes Refusal of informed consent

Ages Eligible for Study
-----------------
Minimum Age: 2 Days
Maximum Age: 36 Months

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Early Visual Functions in Patients at Risk of Developing Cerebral Visual Impairment. A Pilot Study | The score of the functional visual assessment will be obtained at neonatal age and at 1-3-6-9-12-18-24-36 months of life will be analysed at each age and compared to neurodevelopment findings using different scales according to age. These results will be related to the MRI total score (obtained by the sum of scores by site: cortex, basal ganglia, white matter and cerebellum, normal (0), mild abnormal (1), severely abnormal (2)). | 5 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Correlation betwwen functional visual assessment score to MRI score | Results of functional visual assessment will be related to the MRI total score (obtained by the sum of scores by site: cortex, basal ganglia, white matter and cerebellum, normal (0), mild abnormal (1), severely abnormal (2)). | 5 years |