A RCT Evaluating an Online Intervention in Increasing Pneumococcal Vaccination Among Older Adults

Study Overview
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Brief Summary
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To evaluate the relative efficacy of an online intervention based on the Trans-theoretical Model delivered by a fully-automated Chatbot with natural language processing functions versus a control in promoting pneumococcal vaccination uptake among Hong Kong people aged ≥65 years. A total of 374 participants will be randomized evenly to either the intervention group or the control group. Participants in the intervention group will receive Chatbot-delivered interventions tailored to their stage of change regarding PV uptake in a conversational way at Month 0, 1, 2, and 3. Participants in the control group will receive Chatbot-delivered general information related to PV at Month 0, 1, 2, and 3. All participants will be followed up 6 and 12 months after completion of the intervention.

Official Title
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A Randomized Controlled Trial Evaluating a Theory-based Online Intervention Via Fully Automated Chatbot in Increasing Pneumococcal Vaccination Among Community Dwelling Individuals Aged ≥65 Years

Conditions
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Vaccination Refusal

Intervention / Treatment
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* Behavioral: Chatbot-delivered interventions tailored to stage of changes
* Behavioral: Chatbot-delivered standard interventions


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: aged ≥65 years having Hong Kong ID Chinese speaking have not received any penumococcal vaccination willing to be followed up by telephone having a smartphone able to send and read text/voice messages via smartphone. Exclusion Criteria: blindness or deafness not able to communicate with others effectively with known contradictions of pneumococcal vaccination having been diagnosed with major psychiatric illness scored ≤16 in the validated telephone version of the Cantonese Mini-mental State Examination (T-CMMSE).

Ages Eligible for Study
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Minimum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Intervention<br>Participants receive Chatbot-delivered interventions tailored to their stage of change regarding PV uptake in a conversational way at Month 0, 1, 2, and 3. | Behavioral: Chatbot-delivered interventions tailored to stage of changes<br>* Participants receive Chatbot-delivered interventions tailored to their stage of change regarding PV uptake in a conversational way at Month 0, 1, 2, and 3.<br>|
| Active Comparator: Control<br>Participants receive Chatbot-delivered general information related to PV at Month 0, 1, 2, and 3. | Behavioral: Chatbot-delivered standard interventions<br>* Participants receive Chatbot-delivered general information related to PV at Month 0, 1, 2, and 3.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pneumococcal vaccination uptake | Self-reported uptake of pneumococcal vaccination within the 12-month follow-up period | 12 months |