A Study of Physical Activity in Cancer Survivors

Study Overview
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Brief Summary
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The purpose of this study is to determine if increasing physical activity (PA) will increase physical functioning, as measured by cardiovascular endurance, muscular strength, and balance in underserved adult cancer survivors > 60 years of age and/or those of any age residing at a rural address. Also, to determine if increasing PA will increase quality of life (QOL), as measured by physical functioning and fatigue, in underserved cancer survivors >60 years of age and/or those of any age residing at a rural address.

Official Title
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Improving Physical Activity in Rural and Older Cancer Survivors

Conditions
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Cancer

Intervention / Treatment
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* Behavioral: Physical Activity


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adult, cancer survivors (no active disease) at Mayo Clinic Health System (MCHS) in Northwest Wisconsin (NWWI) Any stage cancer Age ≥60 years residing at any address, or ≥18 years residing at a rural address (as defined by Rural America, census.gov) Completed active treatment of surgery, (neo)adjuvant chemotherapy, and/or (neo) adjuvant radiation. Patients receiving adjuvant endocrine therapy, targeted therapy, or immunotherapy therapies are eligible. Ownership of a computer/tablet/smartphone with internet access. Willingness and ability to attend study visits. Must be able to complete semi-tandem (10 seconds), side-by-side tandem (10 seconds and SPPB Score of >6 to qualify for virtual exercise. Must be ambulatory without the use of assisted device(s). Exclusion Criteria: Receiving surgery, (neo)adjuvant chemotherapy, (neo) adjuvant radiation, palliative treatment Are already performing >150 minutes/week of moderate activity or 75 min/week of vigorous physical activity Cancer-free for greater than 5 years Unable to complete weekly interventions/exercise due to traveling or unable to be active for more than 7 consecutive days.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Community Oncology patients entering cancer survivorship<br>Patients participate in a virtual cancer rehabilitation program with weekly virtual visits by a cancer exercise specialist who provides a personalized synchronous exercise plan and receive weekly phone calls over 12 weeks. Patents also wear a Fitbit on study. | Behavioral: Physical Activity<br>* Use Exercise to increase physical activity (PA), as measured by cardiovascular endurance, muscular strength, and balance in underserved cancer survivors >60 years of age and/or those of any age residing at a rural address and to increase quality of life (QOL), as measured by physical functioning and fatigue, in underserved cancer survivors >60 years of age and/or those of any age residing at a rural address.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in physical functioning using Short Physical Performance Battery | Change in physical functioning based on improvement in endurance, strength, and balance assessed using Short Physical Performance Battery (SPPB) pre- and post-12-week exercise intervention. | Baseline; 12 weeks | 
| Change in Quality of Life (QOL) using Patient-Reported Outcomes Measurement Information System (PROMIS) | QOL evaluated based on physical functioning and fatigue, assessed using Patient-Reported Outcomes Measurement Information System (PROMIS) pre- and post-12-week exercise intervention. | Baseline; 12 weeks | 
| Change in satisfaction using a 5-point Likert scale | Satisfaction assessed using a 5-point Likert scale following 12-week exercise intervention and participant-reporting likelihood of recommending program. | Baseline; 12 weeks | 
| Rate of adherence to program based on participation in virtual exercise sessions | Adherence evaluated based on participation in virtual exercise sessions during 12-week exercise intervention. | Baseline; 12 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Rural, Physical Activity