An Online Intervention to Reduce E-cigarette Use and Susceptibility to Smoking in Young Adults

Study Overview
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Brief Summary
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The goal of this intervention development and pilot clinical trial is to determine whether receiving the brief online intervention results in greater reductions in past 7-day e-cigarette use frequency and smoking susceptibility over an 8-week period compared to receiving the control condition in young adults who currently use e-cigarettes. Participants in the experimental condition will be asked to complete the 30-minute mobile-based program. Participants in the assessment-only control will be given the option to access the intervention after they complete their final survey at 8 weeks. All participants will complete our online surveys at baseline as well as 2-weeks, 4-weeks, and 8-weeks post-randomization. Researchers will compare outcomes among the intervention and control groups to determine the efficacy of the intervention.

Official Title
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Development of An Online, Theory-Based Intervention to Reduce E-cigarette Use and Susceptibility to Smoking in Young Adults: A Pilot Study

Conditions
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E-cigarette Use

Intervention / Treatment
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* Behavioral: Live Free From E-cigarettes


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: be between the ages of 18 to 24 be able to read English report vaping at least one day per week in the past month report no history of cigarette use at screening and baseline. Exclusion Criteria: reporting mental health, other drug, or alcohol use problems currently receiving nicotine cessation services

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 24 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Intervention<br>Participants will be asked to complete a 30-minute intervention that is accessible on a mobile device, delivered via a webpage, and personalized to their individual vaping behavior and beliefs (based on the baseline surveys). The intervention will contain personalized normative feedback (PNF), Motivational Enhancement (ME), and education. Participants will complete assessments at baseline as well as 2-weeks, 4-weeks, and 8-weeks post randomization. | Behavioral: Live Free From E-cigarettes<br>* This is a 30-minute online educational program that focuses on providing information about e-cigarette and smoking social norms, harms of e-cigarettes and cigarettes, and ways to quit or reduce using e-cigarettes.<br>|
| No Intervention: Waitlist Control<br>Participants will complete assessments at baseline as well as 2-weeks, 4-weeks, and 8-weeks post randomization. They will not receive the intervention during the active study phase, lasting 8 weeks. Participants will have the option to access the intervention once this active study phase is over. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| E-cigarette Use | Participants will report the number of (1) days they vaped, (2) times they picked up their device to vape per day, and (3) puffs they took before putting their vaping device away per day in the past 7 days and 30 days | 8 weeks | 
| Smoking Susceptibility | 4-item Expanded Susceptibility to Smoking Index (ESSI) | 8 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Perceived harms and benefits of vaping | Using the 21-item Short Form Vaping Consequences Questionnaire (S-VSQ), participants will rate the likelihood that each consequence will occur when they vape. | 8 weeks | 
| Perceived harms and benefits of smoking | Using the 21-item Short Form Smoking Consequences Questionnaire (S-SCQ), participants will rate the likelihood that each consequence will occur when they smoke. | 8 weeks | 
| Motivation to vape | Participants will select which option best describes their interest in e-cigarette use: plan to stop (coded as 1), decrease (2), continue (3) or increase (4) vaping. | 8 weeks | 
| Motivation to smoke | Participants will report if they plan to start smoking (yes/no). | 8 weeks | 
| Quitting vaping self-efficacy | Participants rate their confidence about quitting vaping someday and in the next 6 months on a 5-point scale. | 8 weeks |