Cardiac Index, SVR/SVRI During Weaning From ECC- Data Obtained From Femoral and Radial Artery Transducer

Study Overview
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Brief Summary
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Swan Ganz catheter-Edwards Lifesciences obtains values of cardiac output/index and systemic vascular resistance/index using the mean artery pressure of either radial or femoral artery. During weaning from extracorporeal circulation, arterial waveform-derived cardiac output measurements from radial cannulation site is not reliable as compared with measurements obtained from femoral cannulation site.

Detailed Description
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50 consecutive cardiac surgical patients undergoing on-pump primary coronary artery bypass, valve replacement or combined surgery are included in the study. Cardiac output is measured sequentially by the arterial pressure waveform analysis method from radial and femoral arterial sites

Official Title
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Fluctuation and Realbility of Cardiac Index and SVR/SVRI During Weaning From ECC Regarding Values Obtained From Femoral and Radial Artery Acumen IQ Sensor

Conditions
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Coronary Artery Disease, Aortic Valve Disease, Mitral Valve Disease

Intervention / Treatment
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* Device: CO/CI/SVR


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria:all patients scheduled for elective surgery: coronary artery bypass graft (CABG), valve replacement (VR), combined CABG and VR. - Exclusion Criteria: previous surgery in femoral or iliac artery. -

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Allocation: Non-Randomized
Intervention Model: Crossover Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Cardiac output/index/SVR<br>Record of CO/CI/SVR before and after weaning form ECC from radial and femoral artery cannula. | Device: CO/CI/SVR<br>* fluctuations of CO/CI/SVR regarding data from radial or femoral arterial cannula, and the therapeutic intervention that it demands these values.<br>|
| Active Comparator: Hypotension event<br>Prevent of hypotension event calculated from radial/femoral artery cannula | Device: CO/CI/SVR<br>* fluctuations of CO/CI/SVR regarding data from radial or femoral arterial cannula, and the therapeutic intervention that it demands these values.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cardiac output | Measurement of cardiac output from radial and femoral arterial cannula | 5min after weaning from extracorporeal circulation (ECC) | 
| Prediction of hypotension episode (HPI) | Measurement of possibility of hypotension episode (HPI) from femoral and radial arterial cannula | 5min min after weaning from ECC | 
| Systemic Vascular resistance (SVR) | Measurement of SVR from femoral and radial arterial cannula | 5min min after weaning from ECC | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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cardiac output, cardiac index, systemic vascular resistance