Baduanjin Exercising Effects on Sub-clinical Hypothyroidism and Cognitive Problems

Study Overview
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Brief Summary
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Females with sub-clinical hypothyroidism may exhibit frequent cognitive problems especially if they are elderly

Detailed Description
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Females (forty in number) with sub-clinical hypothyroidism exhibit cognitive problems, they are elderly, will be divided to exercised group (baduanjin training will be applied 5 times per the week, under supervision for 12 weeks, number of patients will be 20) and other non exercised group (number of patients will be 20) . all women of groups will received their prescribed daily one-dose medication tablet (levothyroxine).

Official Title
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Baduanjin Exercising Effects on Women With Hypothyroidism and Cognitive Problems

Conditions
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Subclinical hypothyroïdism, Cognitive Impairment

Intervention / Treatment
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* Behavioral: Baduanjin exercising


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: female with sub-clinical hypothyroidism females with mild cognitive impairment females with obesity (obesity class one) Exclusion Criteria: neurological problems orthopedic problems

Ages Eligible for Study
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Minimum Age: 65 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: group number 1<br>Females with sub-clinical hypothyroidism exhibit cognitive problems (mild cognitive impairement), they will be elderly, will receive baduanjin training that will be applied 5 times per the week, under supervision for 12 weeks, number of patients will be 20), also women of this group will receive their prescribed daily one-dose medication tablet (levothyroxine). | Behavioral: Baduanjin exercising<br>* baduanjin will be applied 5 times per the week, under supervision, for 12 weeks,<br>|
| No Intervention: group number 2<br>Females with sub-clinical hypothyroidism exhibit cognitive problems (mild cognitive impairement), they will be elderly, will receive will receive their prescribed daily one-dose medication tablet (levothyroxine). | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| thyroid stimulating hormone | will be measured in serum of women with hypothyroidism | it will be measured after 12 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| systolic blood pressure | will be measured by manual sphygmomanometer | it will be measured after 12 weeks | 
| triglycerides | will be measured in serum of women with hypothyroidism | it will be measured after 12 weeks | 
| Addenbrooke Cognitive Examination | will assess Cognitive impairment | it will be measured after 12 weeks | 
| diastolic blood pressure | will be measured by manual sphygmomanometer | it will be measured after 12 weeks | 
| low density lipoprotein | will be measured in serum of women with hypothyroidism | it will be measured after 12 weeks | 
| cholesterol | will be measured in serum of women with hypothyroidism | it will be measured after 12 weeks | 
| high density lipoprotein | will be measured in serum of women with hypothyroidism | it will be measured after 12 weeks | 
| body mass index | it will be measure on empty bladder and stomach | it will be measured after 12 weeks |