Drone Biological Samples Transport vs Walking (DBT - Drone Biology Transport)

Study Overview
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Brief Summary
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The transport of biological samples is a key step in the pre-analysis process in health facilities and must meet quality requirements (NF:EN:ISO 151989) to ensure that samples are transported in are transported in good conditions. Still in the experimental stage, drone-based air transport is participating in the aeronautical revolution of the development of unmanned aircraft on board in all areas of society, including health. This first project, led by the Biology Centre and the INNOVABIO Biological Resources Centre of the CHU de CAEN in collaboration with the company Delivrone, will allow to evaluate the feasibility in real condition of the mode of transport by drone versus transport of reference on the quality of a varied panel of medical biology examinations (biochemistry, hematology and haemostasis), on the safety of people (potentially infectious samples), on the control of the delivery time, on the control of the transport temperature (15-25°C ). The samples will be taken on 30 healthy volunteers with a total panel of 23 blood tests performed.

Detailed Description
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Panel of blood tests performed on healthy volunteers samples include : Na, K, Cl, HC03- total protein Ca Creatinine, urea Albumine Bilirubin Liver transaminases (ALT, AST) Alkaline phosphatase GGT LDH C-reactive protein Complete Blood Count Sedimentation rate PT aPTT Fibrinogen D-Dimer

Official Title
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Drone Biological Samples Transport Evaluation Compared to Walking in CHU CAEN NORMANDIE

Conditions
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Healthy

Intervention / Treatment
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* Biological: Biological samples transport and analysis


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Healthy volunteers, over 18 years old Exclusion Criteria: Unhealthy volunteers previously known pregnant or breastfeeding woman

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Pedestrian transport<br>Modality of transport currently used | Biological: Biological samples transport and analysis<br>* Biological samples transport and analysis<br>|
| Drone transport<br>Innovative modality of transport | Biological: Biological samples transport and analysis<br>* Biological samples transport and analysis<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Impact on Sodium test | Evaluation difference between results of Sodium (mmol/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on Potassium test | Evaluation difference between results of Potassium (mmol/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on Chlorure test | Evaluation difference between results of Chlorure (mmol/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on Bicarbonate test | Evaluation difference between results of Bicarbonate (mmol/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on Protein test | Evaluation difference between results of Protein (g/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on Calcium test | Evaluation difference between results of Calcium (mmol/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on Creatinin test | Evaluation difference between results of Creatinin (µmol/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on Urea test | Evaluation difference between results of Urea (mmol/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on Albumin test | Evaluation difference between results of Albumin (g/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on Bilirubin test | Evaluation difference between results of Bilirubin (µmol/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on liver transaminase (ALT) test | Evaluation difference between results of liver transaminase (ALT, U/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on liver transaminase (AST) test | Evaluation difference between results of liver transaminase (AST, U/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on alkalin phosphatase test | Evaluation difference between results of alkalin phosphatase (U/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on GGT test | Evaluation difference between results of GGT (U/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on LDH test | Evaluation difference between results of LDH (U/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on C-reactive Protein test | Evaluation difference between results of C-reactive Protein (mg/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on red blood cells count | Evaluation difference between results of red blood cells (T/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on hemoglobin test | Evaluation difference between results of hemoglobin (g/dL) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on white blood cells count | Evaluation difference between results of white blood cells (G/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on neutrophil cells count | Evaluation difference between results of neutrophil cells (G/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on lymphocytes cells count | Evaluation difference between results of lymphocytes cells (G/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on platelets count | Evaluation difference between results of platelets (G/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on sedimentation rate test | Evaluation difference between results of sedimentation rate (mm) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on PT test | Evaluation difference between results of PT (sec and %) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on a-PTT test | Evaluation difference between results of a-PTT (sec) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on Fibrinogen test | Evaluation difference between results of Fibrinogen (g/L) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 
| Impact on D-Dimer test | Evaluation difference between results of D-Dimer (ng/mL) after drone transport (30 samples) versus pedestrian transport (30 samples). | 1 day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluation of the users security | Report accident of drone or users injuries | 1 day | 
| Evaluation of the users safety | Report numbers of samples broken (contamination risk) after drone transport | 1 day | 
| Temperature | Temperature measurement during the transport. Evaluation of the ambient temperature respect during the transport in the two conditions. | 1 day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Sample transport, Drone, Pre-Analytical Phase