Long-term Follow-up Study of COVID-19

Study Overview
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Brief Summary
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The goal of this observational study is to learn the long-term prognosis of patients and the clinical characteristics of complications, which is of great significance for treatment of novel coronavirus infection pneumonia. This trial plans to include 5700 inpatients with positive SARS CoV-2 nucleic acid test results. This trial does not involve the use of specific drug. Participants's health and psychological status will be observed at the preset time points. The blood, feces, urine samples of patients will be collected for relevant tests.

Detailed Description
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After the patients are enrolled, record the patient's treatment regimens, blood routine results, blood biochemistry results, cytokines results, lung imaging results, and cranial imaging results, understand the patient's current clinical manifestations, evaluate the patient's psychological status and quality of life, and collect samples of the patients' blood, feces, urine, and other related tests. Collection of clinical samples: collect blood, urine, throat swabs and other samples from patients with confirmed novel coronavirus pneumonia (Nucleic acid test positive), and collect samples for relevant tests at 3 months, 6 months, 12 months, 18 months, 24 months and 36 months after discharge of patients, and record the clinical manifestations of patients.

Official Title
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Long-term Large Sample Multicenter Follow-up Study of COVID-19

Conditions
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COVID-19

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients with confirmed COVID-19 Exclusion Criteria: Combined infection with influenza virus, mycoplasma, and chlamydia.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| clinical manifestation |  | 3 months, 6 months, 12 months, 18 months, 24 months, 36 months after patients discharge | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| psychological status |  | 3 months, 6 months, 12 months, 18 months, 24 months, 36 months after patients discharge | 
| quality of life scores |  | 3 months, 6 months, 12 months, 18 months, 24 months, 36 months after patients discharge | 
| cranial imaging results |  | 3 months, 6 months, 12 months, 18 months, 24 months, 36 months after patients discharge | 
| lung imaging results |  | 3 months, 6 months, 12 months, 18 months, 24 months, 36 months after patients discharge | 
| cytokines level |  | 3 months, 6 months, 12 months, 18 months, 24 months, 36 months after patients discharge | 
| blood biochemistry results |  | 3 months, 6 months, 12 months, 18 months, 24 months, 36 months after patients discharge | 
| routine blood test results |  | 3 months, 6 months, 12 months, 18 months, 24 months, 36 months after patients discharge | 
| treatment regimens |  | 3 months, 6 months, 12 months, 18 months, 24 months, 36 months after patients discharge | 
| survival rate |  | 3 months, 6 months, 12 months, 18 months, 24 months, 36 months after patients discharge |