Weight Loss Following an Episode of Pre-eclampsia Using a Dissociated or Hypocaloric Diet in Overweight or Obese Patients

Study Overview
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Brief Summary
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In view of the known link between pre-eclampsia, overweight/obesity and chronic kidney disease, the aim is to offer for obese and overweight patients to reduce their BMI without reducing lean body mass. The POPADIPE project will make it possible to limit overweight or obesity by means of nutritional management chosen by the patient (hypocaloric or a dissociated diet). The latter has been the subject of little scientific investigation, particularly in relation to the management of post-pre-eclampsia.

Official Title
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Weight Loss Following an Episode of Pre-eclampsia Using a Dissociated or Hypocaloric Diet in Overweight or Obese Patients

Conditions
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Obesity, Pre-Eclampsia

Intervention / Treatment
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* Other: Hypocaloric diet
* Other: Dissociated diet


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Person affiliated to social security Free, informed and written consent signed by the participant and the investigator (no later than the day of day of inclusion and before any examination required by the research) Patient over 18 years of age at the time of inclusion and < 45 years of age Having had an pre-eclampsia in the last 5 years according to the definitions of the ISSHP 2018 Patient with a BMI between 25 kg/m² and 40 kg/m² who accepts dietetic follow up Patient with a medical prescription for dietetic follow-up aimed at losing weight loss Patient with a balanced diet Exclusion Criteria: Patients with a mental disability or language barrier that prevents them from understanding or consenting to the study Patients deprived of their liberty by judicial or administrative decision Patients under psychiatric care Patients subject to a legal protection measure Patients with cognitive disorders or defined eating disorders Patients who are pregnant or breast-feeding Patients undergoing steroid treatment and/or immunosuppression Have been on a low-calorie or dissociated diet for at least 6 months Patients with CKD stage ≥ 3A

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Placebo Comparator: control group<br> | Other: Hypocaloric diet<br>* Hypocaloric diet<br>|
| Experimental: innovative group<br> | Other: Dissociated diet<br>* Dissociated diet<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Demonstrate Efficiency of personalised dietary management on weight loss in patients with a history of pre-eclampsia | Efficiency is evaluated by weight measurement | 1 year after care | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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pre-eclampsia, obesity, dissociated diet