Effect of Fenugreek and Cumin Powder on Overweight and Obese People

Study Overview
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Brief Summary
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The objective of this study is to investigate the effect of fenugreek and cumin powder on the anthropometric indices of overweight and obese adults aged 18-30 years. This study design intends to answer following question: Will fenugreek and cumin powder mixture result in change of anthropometric measurements {Body Mass Index[BMI], Waist-Hip Ratio, Fat Mass

Detailed Description
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Obesity is a chronic disorder of carbohydrate and lipid metabolism and is characterized by an increased fat deposition in adipose tissue and other internal organs . Obesity leads to the development of insulin resistance, type-2 diabetes, coronary heart disease, cancer, respiratory disease, and osteoarthritis. The World Obesity Atlas 2022 predicts that one billion people globally, including 1 in 5 women and 1 in 7 men, will be living with obesity by 2030. Pakistan ranks tenth out of 188 countries, with 50% of population overweight or obese Several studies have investigated the effect of fenugreek and cumin supplementation on anthropometric measures but the findings have been inconsistent. Only few studies directly focused on powder supplementation. The study aims to investigate the effect of fenugreek and cumin powder supplementation on body measurements for weight loss. This will help in developing a rather inexpensive, herbal mixture for weight loss. Galactomannan present in fenugreek capture and excrete sugars from body before it moves in the blood, this causes the loss of weight The percent gain in body weight was significantly low in groups supplemented with fenugreek Cumin improves anthropometric indices in overweight. Cumin powder reduced weight, Body Mass Index[BMI], waist circumference, fat mass and percentage significantly. This study consists of following phases Phase 1: Fenugreek and cumin powder preparation Phase 2: 30 Participants will be recruited after filling the consent form and screened through a questionnaire throughout the university. Individuals with Body Mass Index[BMI] >23kg/m2, Waist-Hip-Ratio >0.8 will be recruited in the study after fulfilling the criterion (patients of thyroid, Polycystic ovary syndrome[PCOS], Hypertension[HTN] will be excluded). Participants not following any fitness regime or specific diet will be recruited further. Baseline body measurements will be taken by inbody analyzer. They will be given powder packed in packets to be used for 8 weeks twice a day before breakfast and dinner. Experimental Design : Overweight and obese adults will be assigned to two groups ( Intervention group and control). Participants will be requested to record the following information daily: Consumption of FCP( fenugreek cumin powder) and any side effects if experienced after consumption. The control group will not receive powder or any other intervention. Phase 3: Measurements will be taken after intervention Statistical Analysis: Microsoft excel will be used for data coding. Descriptive analysis will be done by using SPSS[Statistical Package for Social Sciences] version 23( SPSS for windows version 23; SPSS Inc., Chicago). Independent sample t-test and Pearson chi-square will be performed to compare the treatment and control groups. P value < 0.05 will be considered significant for all analysis.

Official Title
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Effect of Fenugreek and Cumin Powder on Anthropometric Indices of Overweight and Obese Adults

Conditions
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Overweight and Obesity

Intervention / Treatment
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* Combination Product: Fenugreek Cumin Powder


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: overweight and obese( BMI>23 kg/m^2) Exclusion Criteria: pregnant women Thyroid PCOS HTN fitness regime specific diet

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 30 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Participants will be divided into two groups. One group will receive the Fenugreek Cumin Powder. The other group will not receive the powder
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: fenugreek cumin powder<br>Overweight and Obese adults in this group will receive fenugreek cumin powder daily twice a day before morning and evening meals for 8 weeks | Combination Product: Fenugreek Cumin Powder<br>* Fenugreek and Cumin seeds will be procured from the market. They will be cleaned of debris, winnowed, and grinded to fine powder passed through a mesh size of 30 for metal cleaning. 5g of fenugreek powder and 5g of cumin powder will be packed in packets. Participants in the intervention group will be instructed to consume the powder before breakfast and dinner with a glass of water.<br>|
| No Intervention: Control group<br>Overweight and obese participants in this group will not receive fenugreek and cumin powder or any intervention for 8 weeks | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| weight change in kilograms | Electronic weighing scale will be used to assess weight change in both groups | change from baseline weight after 2 months | 
| Change in Body fat mass in kilograms and percentages | body fat mass and percentage will be assessed through inbody analyzer 270 | change from baseline readings after 2 months | 
| Change in BMI in kg/m^2 | the BMI will be calculated using weight(kg) and height(m^2) | change from baseline reading after 2 months | 
| Change in Waist- Hip Ratio | the WHR will be calculated using inbody analyzer 270 | change from baseline reading after 2 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Basal metabolic Rate( BMR) | The BMR will be calculated using Inbody analyzer 270 | Change from baseline after 2 months | 
| change in Protein mass of body (grams) | this protein mass will be assessed through Inbody analyzer 270 | change from baseline reading after 2 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Fenugreek powder, Cumin powder, Body Composition, Anthropometric Indices