Resistance Training With Blood Flow Restriction

Study Overview
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Brief Summary
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Blood flow restriction associated with resistance training is suggested to potentiate increases in muscular strength and hypertrophy. This study will compare the effects of resistance training associated with blood flow restriction with a regular resistance training program. Findings of this project will provide important information regarding a promising intervention to potentiate muscle performance.

Detailed Description
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The purpose of this study is to determine alterations in motor unit behavior of the tibialis anterior muscles after a resistance exercise program associated with blood flow restriction. Our working hypothesis is that blood flow restriction to working muscles will induce greater changes in muscle activation, lean mass and muscle size compared with a training at same intensity without blood flow restriction.

Official Title
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Resistance Training With Blood Flow Restriction for the Lower Extremity Muscles

Conditions
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Healthy

Intervention / Treatment
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* Other: Blood flow restriction
* Other: Regular training type 1
* Other: Regular training type 2


Participation Criteria
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Eligibility Criteria
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Exclusion Criteria: presence of neurological diseases, presence of metal implants or joint replacement any restriction to perform physical activity pregnancy

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Group 1<br>Strength training associated with blood flow restriction | Other: Blood flow restriction<br>* Strength training of the lower leg muscles using blood flow restriction<br>|
| Experimental: Group 2<br>Conventional strength training using high loads | Other: Regular training type 1<br>* Strength training of the lower leg muscles using high loads<br>|
| Experimental: Group 3<br>Conventional strength training using low loads | Other: Regular training type 2<br>* Strength training of the lower leg muscles using low loads<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Force | Force of the lower leg muscles using a custom made ergometer | 10 sessions (up to 6 weeks) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Body composition | dual x-ray absorptiometry (DEXA) will be used to assess body composition | Start and end of the protocol | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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motor units, resistance training, strength training, blood flow restriction, body composition