Cohort of Neurovascular Diseases Treated in the Acute Phase and Followed at Lariboisière

Study Overview
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Brief Summary
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Neurovascular diseases can cause ischaemic or haemorrhagic strokes. While the most common, such as atherosclerosis are widely studied, others are less well known, such as arterial dissections or cerebral angiopathies. What's more, most studies are limited to a few years' follow-up and the longer-term evolution of patients is less well assessed. Patient follow-up data available in routine practice and specific enrollment through the headache emergencies of the Lariboisière neurovascular intensive care unit (USINV) could provide a particularly rich resource.

Official Title
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Cohorte de Maladies Neurovasculaires Prises en Charge à la Phase aiguë et Suivies à Lariboisière

Conditions
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Ischemic Stroke, Hemorrhagic Stroke

Intervention / Treatment
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* Other: follow-up


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adult patients ≥18 years Patients admitted to the Neurovascular Intensive Care Unit with acute cerebrovascular disease OR Patients managed for acute cerebrovascular pathology with or without stroke by the Lariboisière neurology team. No opposition from the patient to the research and for patients under guardianship or guardianship or lack of capacity to object (severe impairment of cognitive functions, dementia, etc.), no opposition from the legal representative. Exclusion Criteria: Patient refusing to take part in the study or refusal by the legal representative in the case of patients under guardianship or curatorship Patient suffering from a rare neurovascular disease and being followed at the Centre de référence des maladies vasculaires rares du cerveau et de l'oeil (CERVCO)

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 100 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients treated for acute cerebrovascular pathology cerebrovascular disease<br> | Other: follow-up<br>* Long term follow-up<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of a vascular event | Vascular event is defined as : myocardial infarction, ischaemic or haemorrhagic stroke, recurrence of cerebrovascular disease, systemic embolism, congestive heart disease, vascular or non-vascular death during patient follow-up. | Up to 5 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of a vascular event | Vascular event is defined as : myocardial infarction, ischaemic or haemorrhagic stroke, recurrence of cerebrovascular disease, systemic embolism, congestive heart disease, vascular or non-vascular death during patient follow-up. | Up to 10 years | 
| Modified Rankin score | The modified Rankin score is a 6 point disability scale varying between 0 to 5. The higher the score, the greater the disability. | At 3 months | 
| Modified Rankin score | The modified Rankin score is a 6 point disability scale varying between 0 to 5. The higher the score, the greater the disability. | At 1 year | 
| Modified Rankin score | The modified Rankin score is a 6 point disability scale varying between 0 to 5. The higher the score, the greater the disability. | At 2 years | 
| Modified Rankin score | The modified Rankin score is a 6 point disability scale varying between 0 to 5. The higher the score, the greater the disability. | At 3 years | 
| Modified Rankin score | The modified Rankin score is a 6 point disability scale varying between 0 to 5. The higher the score, the greater the disability. | At 4 years | 
| Modified Rankin score | The modified Rankin score is a 6 point disability scale varying between 0 to 5. The higher the score, the greater the disability. | At 5 years | 
| Modified Rankin score | The modified Rankin score is a 6 point disability scale varying between 0 to 5. The higher the score, the greater the disability. | At 6 years | 
| Modified Rankin score | The modified Rankin score is a 6 point disability scale varying between 0 to 5. The higher the score, the greater the disability. | At 7 years | 
| Modified Rankin score | The modified Rankin score is a 6 point disability scale varying between 0 to 5. The higher the score, the greater the disability. | At 8 years | 
| Modified Rankin score | The modified Rankin score is a 6 point disability scale varying between 0 to 5. The higher the score, the greater the disability. | At 9 years | 
| Modified Rankin score | The modified Rankin score is a 6 point disability scale varying between 0 to 5. The higher the score, the greater the disability. | At 10 years | 
| Occurrence of intercurrent pathologies requiring specific treatment | Pathologies are defined as : anxiety-depressive disorder, dementia, comititude, neoplasia, venous thromboembolism, haemorrhage, systemic disease, respiratory insufficiency | Up to 10 years | 
| Obstetrical prognosis | Incidence of pregnancies, complications, delivery methods | Up to 10 years | 
| Incidence of death | Age and causes of death | Up to 10 years | 
| Prevalence of vascular risk factors | Medical history, LDL (Low Density Lipoprotein), Tobacco, Arterial pressure, HbA1C (glycated hemoglobin) | Up to 10 years | 
| Number of associated treatments | Description of the types of treatment used | Up to 10 years | 
| Number of adverse events | Evaluation of treatment tolerance | Up to 10 years | 
| Treatment adherence |  | Up to 10 years | 
| Incidence of headaches |  | Up to 10 years |