Armenian National Registry of Myocardial Infarction

Study Overview
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Brief Summary
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This is a national, multicenter prospective observational study of patients presenting to hospitals in Armenia with STEMI diagnosis. The main questions it aims to answer are: Determine the rate of in-hospital mortality for the patients with STEMI admitted to the participating hospitals. Compare short and long-term CV and all-cause mortality and hospitalization. Determine how professional guidelines are followed in real-world situations.

Detailed Description
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Although the state program on primary percutaneous coronary intervention in ST elevated myocardial infarction, which was launched in 2015 helped to drastically decrease STEMI mortality rates, patients who had survived usually develop heart failure (HF) which leads to increased economic burden for the Armenian healthcare system. The total duration of the study will be 24 months. The target number of the inclusion is 2500 patients. The follow-up period for enrolled patients will be 12 months.

Official Title
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Armenian National Registry of ST-elevation Myocardial Infarction,a Multicenter Prospective Observational Study With Biocollection

Conditions
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ST Elevation Myocardial Infarction

Intervention / Treatment
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* Other: No specific intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adult patient (≥ 18 years of age), Admitted to the participating centers for a STEMI within 48 hours of symptom onset: characterized by a rise and fall of cardiac markers (troponins) together with ST elevation in at least two contagious leads or LBBB. Have given signed informed consent to participate in the study. Non-Inclusion Criteria: MI occurring ≤ 48 hours after PCI or CABG The patient or the legal representative refused to sign the informed consent Exclusion Criteria: Withdrawal of the informed consent

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: No specific intervention|No specific intervention|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rate of the in-hospital mortality | Determine the rate of the in-hospital mortality for the patients with STEMI admitted to the participating hospitals | During 5 to 7 days of hospitalization | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cardiovascular mortality | Compare short-term (30 days) and long-term (12 months) CV mortality depending on the management strategies. | 30 days and 12 months | 
| All-cause mortality | Compare short-term (30 days) and long-term (12 months) all-cause mortality. | 30 days and 12 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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STEMI, Myocardial infarction, acute coronary syndrome, biobanking, CV mortality