Validating a Clinical Decision Support Tool for Stratifying Stroke Risk for Dizziness/Vertigo

Study Overview
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Brief Summary
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This study aims to validate a machine learning model that stratifies the risk of stroke in patients who present to the emergency department with dizziness or vertigo.

Detailed Description
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This is a cross-sectional, hospital-based study, with no randomization procedure. Over a 21-month period, approximately 600 subjects will be enrolled. The study will assess the risk of stroke in each patient using a machine-learning model. To detect ischemic or hemorrhagic stroke, each patient will undergo a non-contrast brain magnetic resonance imaging study. The predictive performance of the machine-learning model will be evaluated in terms of accuracy, precision, recall, F1 score, and area under the receiver operating characteristics curve.

Official Title
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Validating a Clinical Decision Support Tool for Stratifying Stroke Risk in Patients Presenting With Dizziness to the Emergency Department

Conditions
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Dizziness, Vertigo

Intervention / Treatment
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* Radiation: Magnetic resonance imaging


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Presenting to the emergency department with dizziness or vertigo Aged ≥ 20 Dizziness or vertigo lasting for at least 1 hour and < 7 days Persistent dizziness or vertigo at the time of the examination at the emergency department Exclusion Criteria: Having 5 or more prior episodes similar in quality, intensity, and duration to the current symptoms, with at least one episode more than a year prior and one within the past year Having frank stroke-like symptoms or signs, such as hemiparesis, facial asymmetry, dysarthria, dysphasia, ataxia, gaze palsy Consciousness disturbance, Glasgow coma scale < 13 Severe dementia Recent stroke within 3 months Dizziness or vertigo thought to be the result of head injury, hypotension, medication/drug intoxication, hypoglycemia, electrolyte imbalance, anemia, hepatic encephalopathy, hydrocephalus, etc Concomitant head or neck trauma Severe degenerative cervical spondylosis Having contraindications to magnetic resonance imaging examination

Ages Eligible for Study
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Minimum Age: 20 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Dizziness/vertigo<br>Patients aged 20 or above, presenting to the emergency department with dizziness or vertigo. | Radiation: Magnetic resonance imaging<br>* Brain magnetic resonance imaging<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of participants with stroke | Number of participants with ischemic or hemorrhagic stroke confirmed by brain magnetic resonance imaging | Between 24 hours and 14 days after the emergency department visit | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Dizzy, Vertigo, Stroke, Machine learning