Comparison of Erector Spina Plan Block and Trnsversus Abdominis Plan Block in Laparoscopic Nephrectomy: Prospective Randomized Clinical Trial

Study Overview
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Brief Summary
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Nephrectomy pain was higher. erector spina plan block and transversus abdominis plan block had shown to be effective in abdominal surgeries. This study aimed to compare these two bloc analgesic efficacy in laparoscopic nephrectomy patients. The primary aim is postoperative morphine consumption.

Detailed Description
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Patients ASA 18-65 who will undergo laparoscopic nephrectomy are included in this prospective randomized clinical trial. Patients will be divided into two groups; erector spina and transversus abdominis plane block. Anesthesia will. induced with propofol, fentanyl, and rocuronium will be administered for muscle relaxation. Bispectral index monitoring will be used for monitorisation of the depth of anesthesia. Remifentanil was used during the whole procedure. the amount of consumption will be recorded. Patient-controlled device will be used with morphine. The postoperative morphine consumption will also be recorded.

Official Title
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Comparison of Erector Spina and Transversus Abdominus Plan Blocks

Conditions
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Laparoscopic Nephrectomy

Intervention / Treatment
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* Procedure: laparoscopic nephrectomy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 18-65 age patients undergoing laparoscopic nephrectomy ASA 1-3 Exclusion Criteria: <18- >65 < age patients undergoing open nephrectomy ASA 4-5

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Allocation: Randomized
Intervention Model: Crossover Assignment
Interventional Model Description: erector spina and transversus abdominis plane blocks
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Erector spina plan block<br>Erector spina plan block will be administered to the patients in this group. | Procedure: laparoscopic nephrectomy<br>* laparoscopic nephrectomy<br>|
| Active Comparator: Transversus abdominis plan block<br>Transversus abdominis plan block will be administered to the patients in this group. | Procedure: laparoscopic nephrectomy<br>* laparoscopic nephrectomy<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative morphine consumption | morphine patient controlled analgesia was applied to the patients | 24 hour postoperatively | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Peroperative remifentanil consumptions | continious remifentanil infusion was applied | peroperatively | 
| postoperative analgesia numeric rating scales | patients will give numbers to their pain first hour, 6th hour and 24 th hour after surgery | postoperative 24 hours | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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laparoscopy, nephrectomy, erector spina plan block, transversus abdominis plan block, morphine consumption, analgesia