Perioperative Vaping Complications

Study Overview
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Brief Summary
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Prospective observational study evaluating the incidence, and qualifying the types, of perioperative pulmonary complications in patients that vape.

Detailed Description
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The primary objective of our study is to determine the rate at which patients that vape or use e-cigarettes experience perioperative pulmonary complications during and following general anesthesia. Complications of interest will include postoperative atelectasis with hypoxemia necessitating oxygen therapy, pneumothorax, pneumonia, bronchospasm, bronchospasm requiring bronchodilator therapy, exacerbation of underlying pulmonary disease, pneumonia, ARDS, and acute respiratory failure. Hospital course, including prolonged PACU stay, prolonged hospital admission for inpatients, and rate of ICU admissions, will also be investigated. A secondary objective will be to further investigate and include the relationship between vaping cessation timeline in the preoperative period and the occurrence of PPCs, which is similarly underreported in the literature. Furthermore, the study will assess how effectively anesthesia providers are screening for vaping or e-cigarette use as part of the preoperative evaluation, given that it is unclear whether anesthesiologists and surgeons routinely ask patients explicitly about vaping in the pre-operative setting. This lack of representative screening for vaping further obscures an understanding of the relationship between vaping, vaping cessation, and PPCs.

Official Title
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Vaping Associated Perioperative Pulmonary Complications - Anesthetic Implications

Conditions
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Vaping, Complication of Anesthesia

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Surgical Patient General Anesthesia Hx of vaping Age ≥12 Exclusion Criteria: Age <12 Pregnancy Active preoperative pulmonary infection Recent pulmonary infection (within 8 weeks) Active tobacco smoker Poorly controlled reactive airway disease (requires more than PRN albuterol) Non-Lung Protective Ventilation

Ages Eligible for Study
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Minimum Age: 12 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Vaping patients<br>Includes patients that actively vape that are undergoing general anesthesia | |
| Non-vaping patients<br>Includes patients that do not actively vape that are undergoing general anesthesia | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Perioperative pulmonary complications | Complications of interest will include postoperative atelectasis with hypoxemia necessitating oxygen therapy, pneumothorax, pneumonia, bronchospasm, bronchospasm requiring bronchodilator therapy, exacerbation of underlying pulmonary disease, pneumonia, ARDS, and acute respiratory failure. Hospital course, including prolonged PACU stay, prolonged hospital admission for inpatients, and rate of ICU admissions, will also be investigated Complications of interest will include postoperative atelectasis with hypoxemia necessitating oxygen therapy, pneumothorax, pneumonia, bronchospasm, bronchospasm requiring bronchodilator therapy, exacerbation of underlying pulmonary disease, pneumonia, ARDS, and acute respiratory failure. Hospital course, including prolonged PACU stay, prolonged hospital admission for inpatients, and rate of ICU admissions, will also be investigated | From the initiation of general anesthesia through postoperative day seven. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Vaping cessation timeline | Includes the relationship between vaping cessation timeline in the preoperative period and the occurrence of postoperative pulmonary complications | From the initiation of general anesthesia through postoperative day seven. | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Perioperative, Vaping, Hypoxemia, Bronchospasm, Pneumonitis