Long-Term Outcomes of Robot-Assisted Radical Cystectomy: A Real-World Study

Study Overview
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Brief Summary
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A multicenter, retrospective research was conducted. Patients who underwent robot-assisted radical cystectomy (RARC) from for bladder cancer in 32 institutions in China were enrolled in this study. Baseline condition, perioperative, pathological, and survival outcome were collected. The study was aimed to report the real-world condition of RARC in China, and evaluate its effectiveness.

Official Title
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Long-Term Outcomes of Robot-Assisted Radical Cystectomy: A Real-World Study

Conditions
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Bladder Cancer, Robot-assisted Radical Cystectomy

Intervention / Treatment
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* Procedure: Robot-assisted radical cystectomy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: >18 years old; Clinical stage Ta-T4a/N0-3/M0. Exclusion Criteria: Severe cardiovascular disease; history of previous major abdominopelvic surgery; patients with distant metastases; medical history of malignancy in other organs.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Sun Yat-sen Memorial Hospital<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| Renji Hospital, Shanghai Jiaotong University School of Medicine<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| The Third Medical Centre of Chinese PLA General Hospital<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| The First Affiliated Hospital of Zhengzhou University<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| Southwest Hospital, Third Military Medical Hospital (Army Medical University)<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| Tongji Hospital Affiliated to Tongji Medical College Hust<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| The First Affiliated Hospital of Xi'an Jiaotong University<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| The First Affiliated Hospital of Navy Medical University<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| The First Affiliated Hospital of Nanchang University<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| Zhongda Hospital Southeast University<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| The Second Xiangya Hospital, Central South University<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| The First Affiliated Hospital of Nanjing Medical University<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| Gansu Provincial Hospital<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| The Affiliated Yantai Yuhuangding Hospital of Qingdao University<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| West China Hospital, Sichuan University<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| The First Hospital of China Medical University<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| The Third Xiangya Hospital of Central South University<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| General Hospital of Central Theater Command<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| Kunming First People's Hospital<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| The East Campus of Qingdao Municipal Hospital<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| The second Affiliated Hospital of Kunming Medical University<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| Second Hospital of Dalian Medical University<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| The Second Affiliated Hospital of Xi'an Jiaotong University<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| The First Hospital of Jilin University<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| Zhejiang Cancer Hospital<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| Peking University Third Hospital<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| Changzheng Hospital, Naval Medical University<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| Peking Union Medical College Hospital<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| The First Affiliated Hospital of Chongqing Medical University<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|
| Beijing United Family Hospital and Clinics<br> | Procedure: Robot-assisted radical cystectomy<br>* Robot-assisted radical cystectomy<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Overall survival | Time from surgery until death from any cause | Five years | 
| Recurrence-free survival | Time from surgery to tumor recurrence which identified either pathologically or radiographically | Five years | 
| Cancer-specific survival | Time from date of surgery to death due to bladder cancer | Five years |