linjc16/ctgov huggingface dataset:
Lifestyle Changes by the COVID-19 (Coronavirus Disease 2019) Pandemic in Children With Developmental Delays

Study Overview
=================
Brief Summary
-----------------
To evaluate the lifestyle changes caused by the COVID-19 pandemic in children with developmental delays in Taiwan.

Detailed Description
-----------------
Two hundred and sixty children with developmental delays in Shin Kong Wu Ho-Su Memorial Hospital will be included. The lifestyle questionnaire will evaluate the lifestyle changes of children with developmental delays during home isolation and release from home isolation during the COVID-19 pandemic in Taiwan. The parents of children with developmental delays will fill out the questionnaire.

Official Title
-----------------
Lifestyle Changes by the COVID-19 (Coronavirus Disease 2019) Pandemic in Children With Developmental Delays

Conditions
-----------------
Lifestyle-related Condition, COVID-19 Pandemic, Children With Developmental Delays

Intervention / Treatment
-----------------
* Other: lifestyle questionnaire


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: children diagnosed with developmental delays Exclusion Criteria: children without developmental delays

Ages Eligible for Study
-----------------
Minimum Age: 1 Year
Maximum Age: 6 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: lifestyle questionnaire|The changes in lifestyle by lifestyle questionnaire during and after home isolation|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| sleeping quality change by lifestyle questionnaire | Sleep quality changes during and after home isolation during the COVID-19 pandemic by lifestyle questionnaire. The minimum and maximum values range from 1 to 5; higher scores mean a worse outcome. | during and after home isolation through study completion, an average of 6 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
COVID-19 pandemic, lifestyle, sleep, children with developmental delays
Gastric Volume After Drinking 175 ml of Ice Water Prior to Gastroscopy in Healthy Adult Patients

Study Overview
=================
Brief Summary
-----------------
Recommendation for fluid fasting is two hours prior to anaesthesia, however, less may be acceptable. The current study compares ingestion of 175 ml ice water prior to elective gastroscopy vs. standard fasting on gastric residual volume.

Detailed Description
-----------------
Recommendations regarding fasting requirements prior to general anaesthesia is two hours for fluids. Recent research indicates that reduced fluid fasting time may be acceptable. The current study aimed to compare ingestion of 175 ml ice water 15 minutes prior to procedure compared to standardized fasting regimen on residual gastric volumes in patients receiving elective gastroscopy, as these volumes may have implications for fasting requirements.

Official Title
-----------------
Gastric Emptying and Gastric Volume After Ingestion of 175 ml of Ice Water Prior to Elective Gastroscopy in Healthy Adults

Conditions
-----------------
Fasting, Perioperative Pulmonary Aspiration

Intervention / Treatment
-----------------
* Other: Ice water


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Scheduled for elective gastroscopy in a medical outpatient clinic American Society of Anesthesiologists physical status classification system category (ASA score) I or II Age 18 years or above Exclusion Criteria: Any increased risk of aspiration, eg. dysphagia, previous aspiration, non-fasting status, or known alcohol abuse Suspected delayed gastric emptying, eg. regular opioid use within three days Enteral pre-medication required Any structural gastric or esophageal diseases

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 175 ml ice water<br>Ingestion of 175 ml ice water 15 minutes prior to gastroscopy | Other: Ice water<br>* Ingestion of 175 ml iced tap water 15 minutes prior to elective gastroscopy<br>* Other names: Iced tap water;|
| No Intervention: Fasting<br>Continued fasting | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Gastric residual volume | Aspired residual gastric fluid volume at start of gastroscopy | 15 minutes | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Nausea and dyspepsia | Proportion of patients reporting nausea or dyspeptic symptoms prior to gastroscopy | 15 minutes | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Gastroscopy, Gastric volume, Anaesthesia
Using YouTube to Learn Anatomy: Perspectives of Mexican Medical Students

Study Overview
=================
Brief Summary
-----------------
The study is aimed at exploring the popularity, impact, and usefulness of using YouTube in learning anatomy as perceived by Mexican medical students studying at different universities along the country

Official Title
-----------------
Using YouTube to Learn Anatomy: Perspectives of Mexican Medical Students

Conditions
-----------------
Learning Techniques

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Student of medicine Exclusion Criteria: Not student of medicine
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Use of Youtube | percentage of students that use youtube | In the last year |
Safety of Omitting Axillary Surgery in Breast Cancer Patients With Isolated Chest Wall Recurrence

Study Overview
=================
Brief Summary
-----------------
The axillary management of breast cancer patients with operable isolated chest wall recurrence after mastectomy is unclear. We aim to determine if axillary restaging surgery can be safely omitted with no increased recurrences in this group of patients.

Official Title
-----------------
Oncological Safety of Omitting Axillary Surgery in Breast Cancer Patients With Isolated Chest Wall Recurrence After Mastectomy

Conditions
-----------------
Breast Cancer, Recurrent Disease

Intervention / Treatment
-----------------
* Procedure: axillary surgery


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Mastectomy patients who developed pathologically confirmed invasive isolated chest wall recurrence. - Exclusion Criteria: -Patients with bilateral cancers Patients with evidence of concomitant distant or/and regional recurrences Patients who did not have surgery for their isolated chest wall recurrences.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 100 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| axillary surgery group<br>this group of patients had axillary surgery for axilla staging | Procedure: axillary surgery<br>* one group undergoes axillary surgery<br>|
| no axillary surgery group<br>this group of patients had no axillary surgery for axilla staging | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| recurrence | axillary or distant recuurences | from date of surgery to date of recurrence, up to 5 years |
Effects of Probiotics on Streptococcus Mutans ve Lactobacillus Spp

Study Overview
=================
Brief Summary
-----------------
To evaluate the change of S. mutans and Lactobacillus spp. counts after all dental treatments were completed under general anesthesia and compare the groups in case of using probiotics and not using probiotics with the time for 6-months follow-up period.

Detailed Description
-----------------
Fifthy-eight pediatric patients without any systemical diseases whose dental treatments were completed under general anesthesia were included in the study. The study was carried out as two-groups; Group A: Patients who started using probiotics after general anesthesia and Group B: Patients who did not use probiotics after general anesthesia. The counts of S. mutans and Lactobacillus spp. were determined by quantitative polymerase chain reaction (qPCR) by analysis of saliva samples taken from all patients on the day before the general anesthesia (T0), at 1-month (T1), 3-month (T2) and 6-month (T3) follow-up periods. The statistical significance level was accepted as p<0.05.

Official Title
-----------------
Evaluation of Streptococcus Mutans and Lactobacillus Species Due to Probiotic Use in Oral Flora

Conditions
-----------------
Tooth Decay, Probiotics, Streptococcus Mutans

Intervention / Treatment
-----------------
* Dietary Supplement: Probiotic use


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Every included child had at least 8 tooth with caries. Exclusion Criteria: Patients who would not be able to give saliva samples due to high anxiety or lack of saliva were not included in this study.

Ages Eligible for Study
-----------------
Minimum Age: 2 Years
Maximum Age: 12 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: 2 separate groups, experimental and control, 6 month follow-up period, randomized distribution
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Probiotics<br>Group A-Probiotics group: Patients who started using probiotic drops after general anesthesia procedure | Dietary Supplement: Probiotic use<br>* Probiotics were used for 3 months and all participated patients were followed for 6 months.<br>* Other names: Follow-up after general anesthesia;|
| No Intervention: Control<br>Group B-Control group: Patients who did not use any probiotics after general anesthesia procedure | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| S mutans count | CFU | 6 month | 
| Lactobacillus spp count | CFU | 6 month | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
tooth caries, probiotics, qPCR, Streptococcus mutans, Lactobacillus
Effect of Cervical Paraesophageal Lymph Node Metastasis Versus Supraclavicular Lymph Node Metastasis on the Overall Survival of Patients With Thoracic Esophageal Squamous Cell Carcinoma: An Observational Study

Study Overview
=================
Brief Summary
-----------------
The goal of this observational study is to learn about in health conditions of ESCC. The main question[s] it aims to answer are: •Lymph node metastasis(LNM) in cervical paraesophageal or supraclavicular which influence OS more. Participants will describe the main status quo after surgery Researchers will compare Lymph node metastasis(LNM) in cervical paraesophageal and supraclavicular to see if dead.

Detailed Description
-----------------
Demographic and pathologic data, including gender, age, pathological T stage, pathological N stage, 8th tumor-node-metastasis (TNM) stage, tumor location, tumor grade, lymphovascular invasion, perineural invasion, LNM, cervical paraesophageal LNM, supraclavicular LNM, and radical resection, were collected from the Sichuan Cancer Hospital and Institute Esophageal Cancer Case Management (SCH-ECCM) database.

Official Title
-----------------
Effect of Cervical Paraesophageal Lymph Node Metastasis Versus Supraclavicular Lymph Node Metastasis on the Overall Survival of Patients With Thoracic Esophageal Squamous Cell Carcinoma: An Observational Study

Conditions
-----------------
Esophageal Cancer

Participation Criteria
=================
Eligibility Criteria
-----------------
The inclusion criteria were as follows: patients who had undergone esophagectomy and patients who exhibited LNM in the supraclavicular region. The exclusion criteria: tumor location outside the thoracic region, pathological examination results confirming the presence of non-squamous cell carcinoma, - patients with both cervical paraesophageal LNM and supraclavicular LNM, or those with missing required data
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Diagnosed with supraclavicular LNM<br>There was no intervention(s) in any group | |
| Diagnosed with paraesophageal LNM<br>There was no intervention(s) in any group | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Overall survival | OS was calculated from the month and year of surgery until the time of death or the last follow-up in March 2021. | 2009.01.01-2017.12.30 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
oesophageal squamous cell carcinoma; cervical paraesophageal lymph node metastasis; supraclavicular lymph node metastasis; lymphadenectomy; esophagectomy
Outcomes of Dynamic Foot Print in Chronic Ankle Instability Versus Healthy Subjects

Study Overview
=================
Brief Summary
-----------------
compare the dynamic foot print outcomes in subjects suffering from chronic ankle sprain to heathy subjects

Official Title
-----------------
Outcomes of Dynamic Foot Print in Chronic Ankle Instability Versus Healthy Subjects

Conditions
-----------------
Ankle Sprains

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: subjects were suffering from chronic ankle sprain. age ranged from 20-30 years old. Normal BMI (ranged from 18 to 24.9 Kg/m2) Exclusion Criteria: not suffering from any neuromuscular disorders , deformities

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 30 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| chronic ankle sprain group<br> | |
| health subjects group<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| loading force | force plate form is used to determine foot print parameter e.g. loading force | through study completion, an average of 3 months | 
| foot print parameter - ankle rocker | force plate form is used to determine foot print parameter ankle rocker | through study completion, an average of 3 months |
System Accuracy of the Blood Glucose Monitor for Personal Use Contour Care

Study Overview
=================
Brief Summary
-----------------
This study assesses the system accuracy of a blood glucose monitoring system in accordance with DIN EN ISO 15197:2015

Official Title
-----------------
Evaluierung Des Blutglukose Monitoring Systems Contour Care Der Firma Ascensia Diabetes Care Deutschland GmbH gemäß DIN EN ISO 15197:2015

Conditions
-----------------
Diabetes

Intervention / Treatment
-----------------
* Diagnostic Test: blood glucose measuremen subject
* Diagnostic Test: blood glucose measuremen reference


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion criteria: Male or female patients with hypo-, eu- or hyperglycaemia The written informed consent had to be signed The volunteers must be older than 18 years The volunteers have legal capacity and are able to understand meaning, nature and possible consequences of the procedures involved Exclusion criteria: Pregnancy or lactation Acute or chronic diseases with the risk of aggravation by the measure A current constitution that does not allow participating in the study Participation in another study or activity with the blood glucose measuring system evaluated in the present study Application of substances listed in Appendix A of DIN EN ISO 15197:2015

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Subject glucometer measurement<br>Blood glucose measurement BGM for personal use | Diagnostic Test: blood glucose measuremen subject<br>* measurement of the blood glucose concentration of subject using BGM and capillary finger tip blood<br>Diagnostic Test: blood glucose measuremen reference<br>* measurement of the blood glucose concentration of subject using reference method and capillary finger tip blood<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Analysis of system accuracy based on DIN EN ISO 15197 | Assessment of the analytical measurement performance of the blood glucose monitor based on procedures defined in DIN EN ISO 15197 | 1 Day |
Sonu Real-World Use Clinical Study to Treat Moderate to Severe Nasal Congestion

Study Overview
=================
Brief Summary
-----------------
Real world utilization of Acoustic Resonance Therapy for symptoms of Nasal Congestion

Detailed Description
-----------------
This is an interventional study designed to gather data on real world utilization of Acoustic Resonance Therapy for treating moderate to severe nasal congestion

Official Title
-----------------
Sonu Real-World Use Clinical Study to Treat Moderate to Severe Nasal Congestion

Conditions
-----------------
Nasal Congestion

Intervention / Treatment
-----------------
* Device: Sonu Acoustic Resonance Therapy


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 18 years of age and older Present with symptoms of chronic nasal congestion Have a 24 hour reflective nasal congestion subscore of the TNSS of 2 or more on a 0 to 3 scale at the time of screening Exclusion Criteria: Head, nasal or sinus surgery within 3 months Pregnancy

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Interventional<br>Participants will receive Acoustic Resonance Therapy using the Sonu headband and App, twice a day, for 90 days | Device: Sonu Acoustic Resonance Therapy<br>* Participants will receive Sonu treatment twice a day for 90 days<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Weekly Utilization-Frequency | Weekly utilization of Sonu treatment, measured as the frequency or number of times used per week | 90 days | 
| Weekly Utilization-Duration | Weekly utilization of Sonu treatment, measured as the duration of treatment received per week | 90 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Total Nasal Symptom Score (TNSS) | 24-hour TNSS; Minimum score=0 (no symptoms), Maximum score=12 (severe symptoms). Lower scores are better and reflect less symptoms. | 90 days | 
| Asthma Control | Asthma Control Test (ACT) Score; Minimum score = 5 (poor control of asthma). Maximum score = 25 (complete control of asthma). Higher scores reflect greater asthma control. | 90 days |