The Relationship Between Preoperative Levels of Ionized Magnesium and Risk of Acute Kidney Injury After Cardiac Surgery

Study Overview
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Brief Summary
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Detection the relationship between preoperative ionized magnesium levels and the risk of acute kidney injury after cardiac surgery.

Detailed Description
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Acute kidney injury (AKI) is a major medical problem that is of particular concern after cardiac surgery. The reported prevalence of cardiac surgery-associated acute kidney injury (CSA-AKI) is up to 30% and is independently associated with an increase of morbidity and mortality .So this study is for measuring preoperative ionized magnesium levels of patients who will undergo cardiac surgeries then measuring postoperative serum creatinine, BUN and urine output to detect if they developed AKI or not and if there is a relationship between the post cardiac surgery AKI and preoperative ionized magnesium levels.

Official Title
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The Relationship Between Preoperative Levels of Ionized Magnesium and Risk of Acute Kidney Injury After Cardiac Surgery

Conditions
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Magnesium Disorder

Intervention / Treatment
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* Other: magnesium levels


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients more than or equal 18 yrs. patients undergoing cardiac surgery between July 2023 and July 2024 Exclusion Criteria: patients with known Kidney disease. patients less than 18 yrs

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Adults undergoing cardiac surgery without preoperative renal affection<br>Detect the preoperative magnesium levels in adults undergoing cardiac surgery without preoperative renal affection and follow up if they developed postoperative acute kidney injury or not. | Other: magnesium levels<br>* Detection of the relationship between cardiac surgery associated AKI and preoperative magnesium levels.<br>* Other names: Serum creatinine and blood urea nitrogen (BUN);|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Post cardiac surgery AKI according to KDIGO criteria with low preoperative magnesium level | Measuring preoperative magnesium level and postoperative kidney functions in form of serum creatinine in umol/L , BUN in mmol/L and urine output ml/h to detect the relationship between preoperative low magnesium level and risk of acute kidney injury after cardiac surgery. | Baseline | 
| Post cardiac surgery AKI according to KDIGO criteria with normal or high preoperative magnesium level | Measuring preoperative magnesium level and postoperative serum creatinine, BUN and urine output to detect the relationship between preoperative magnesium level and risk of acute kidney injury after cardiac surgery. | basline | 
| Post cardiac surgery normal kidney functions with low preoperative magnesium level | Measuring preoperative magnesium level and postoperative serum creatinine, BUN and urine output to detect the relationship between preoperative magnesium level and risk of acute kidney injury after cardiac surgery. | basline |