Does Subtotal Cholecystectomy Rate for Acute Cholecystitis Change With a Previous ERCP?

Study Overview
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Brief Summary
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Study is designed to investigate whether the history of ERCP is associated with subtotal cholecystectomy rates in patients underwent laparoscopic cholecystectomy operations with the diagnosis of acute cholecystitis.

Detailed Description
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The results of patients who underwent surgery for acute cholecystitis in a single center between January 2016 and December 2019 were included and evaluated retrospectively. Primary outcome was subtotal cholecystectomy rate. Secondary outcomes were conversion to open, complications and serious complications. Within examining demographic findings, operative records (rates for subtotal cholecystectomy and conversion to open, operative duration) and follow-up results (postoperative complications, serious complications, length of hospital stay and mortality) for all cases were investigated. Complications that Clavien-Dindo Score ≥ 3 accepted as serious complication. Intraoperative detection of gallbladder perforation was also noted and included in comparison. Any biliary tract complication that needed any percutaneous or endoscopic intervention to handle was named as biliary leak in the study.

Official Title
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Does Subtotal Cholecystectomy Rate for Acute Cholecystitis Change With a Previous ERCP?

Conditions
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Cholecystectomy, Laparoscopic, Cholangiopancreatography, Endoscopic Retrograde

Intervention / Treatment
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* Procedure: ERCP


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients operated with the diagnosis of acute cholecystitis with an age greater or equal to 18 years old in a single center between January 2016 and December 2019 Exclusion Criteria: Initial and direct preferance of open method Being diagnosed with malignity after histopathological evaluation Being operated just before one week after ERCP or after more than six weeks after ERCP

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Standard (non-ERCP) Group<br>Patients who underwent surgery for acute cholecystitis without a previous ERCP history. | |
| ERCP group<br>Patients who underwent surgery for acute cholecystitis with a previous ERCP history. | Procedure: ERCP<br>* Patients separated to two groups according to having a ERCP history before the operation<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Subtotal Cholecystectomy Rate | Rate of patients needed subtotal cholecystectomy after initial intent of starting laparoscopic to the cholecystectomy | Intraoperative | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Conversion to open | Rate of patients needed conversion to open after initial intent of starting laparoscopic to the cholecystectomy | Intraoperative | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Acute Cholecystitis, Laparoscopic Subtotal Cholecystectomy