Pulmonary Function and Qi Deficiency Predicted by Acoustic Analysis

Study Overview
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Brief Summary
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Acoustic analysis is a method of clinically non-invasive, low-cost, remote-operation, and can avoid direct face-to-face contact. It has been proved by many researches in recent years that it has a high diagnostic rate in predicting diseases. Lung function is closely related to human vocalization and has the potential and need for sound analysis. From literature review, it can be inferred that the Qi deficiency constitution in TCM is related to the strength of heart and lung function.The purpose of this study is to investigate the correlation between cardiopulmonary function and Qi deficiency, and to predict the correlation between the data by computer algorithm and artificial intelligence. Furthermore, the artificial intelligence (AI) self-correction ability can be combined with sound analysis to simulate a sound analysis system that can predict cardiopulmonary function and degree of qi deficiency only through sound information. Research motivation and questions: Is the sound characteristic of an individual related to individual's qi deficiency and cardiopulmonary function? Can lung function and qi deficiency be measured by sound analysis? To understand the correlation between Qi deficiency and cardiopulmonary endurance index. Is there any difference in sound characteristics before and after step test and does it help predicting cardiopulmonary function?

Official Title
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Prediction of Pulmonary Function and Qi Deficiency Based on the Acoustic Analysis Before and After Step Test

Conditions
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Qi-Xu; Qi Deficiency, Pulmonary Function; COPD

Intervention / Treatment
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* Behavioral: 3 minutes step test


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age: over 20 years old. Agreed and signed Informed Consent Form. Exclusion Criteria: Known heart diseases, acute severe respiratory infection, severe arthritis or other orthopedic disabilities, severe hypertension, or pregnant.

Ages Eligible for Study
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Minimum Age: 20 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Before step test<br>Before step test. -Participants record their before-step-test voice. | |
| After step test<br>After step test. -Participants record their after-step-test voice. | Behavioral: 3 minutes step test<br>* 3 minutes step test- Stair hight:20 cm, Pace: 96 steps per minute<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| FVC<80% | FVC<80% | 10 mins | 
| FVC>80% | FVC>80% | 10 mins | 
| Qi deficient | Qi deficient | 10 mins | 
| step test: heart rate recovery | Tecumseh step test. | 15 mins | 
| Voice record | /a/, /e/, /i/, /o/, /u/, five seconds each, 3 times per person | 15 mins | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Qi-Xu; Qi deficiency, Pulmonary Function; COPD, Step test; heart recovery rate