Effect of Early Eating and Stair Climbing on Body Composition

Study Overview
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Brief Summary
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To our knowledge, as of this day there are only four studies which examined the effects of eTRE with a duration of 12 weeks. There are no studies that examined this phenomenon beyond 12 weeks, one study that lasted five weeks and four studies that lasted 4 weeks or less, some even days. The four studies that lasted 12 weeks in duration all have opportunities to improve upon, which will be discussed here. The first study performed by Gabel et al., focused primarily on measuring body weight, not body composition in older adults. The eating window also began later in the morning at 1000h and finished at 1800h. There also was no restriction on participants consuming caffeine during the fasting window. The second study conducted by Gasmi et al., was focused on strictly older male participants that were active and healthy, again, without measuring body composition. The third study conducted by Wilkinson et al., did not measure body composition and the eating window lasted 10 hours instead of 8. The fourth study performed by Chow et al., examined eTRE with adults aged 45+/-12 years old and did not mention any exclusion criteria based upon physical activity levels or restrictions on caffeine/artificial sweetener intake during the fasting window. Furthermore, none of the studies mentioned above examined eTRE against eTRE with Brief Intense Stair Climbing (BISC) directly. We believe that the proposed study will address the concerns mentioned previously and further knowledge associated with eTRE.

Official Title
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Effect of Early Time Restricted Eating and Brief Intense Stair Climbing on Body Composition

Conditions
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eTRE (Early Time Restricted Eating), eTRE With BISC (Brief Intense Stair Climbing)

Intervention / Treatment
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* Behavioral: eTRE
* Behavioral: eTRE with BISC


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: sedentary- lightly physically active (<7,500 steps daily) BMI > 25 • 18-39 years old Exclusion Criteria: Have diabetes (self-reported) Have history of smoking (self-reported) Have history of cardiovascular disease (self-reported) Have BMI of <24.9 Are pregnant or become pregnant during the study (self-reported) Take medication for weight loss (self-reported) Physical activity level > 7500 steps/day Unstable weight for 3 months prior to commencement of study (>4kg weight loss/gain) • Employed in a shift work position

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 39 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: eTRE<br>participants allocated to this group are required to consume food during 0800h and 1600h. | Behavioral: eTRE<br>* eating between 0800h and 1600h daily<br>|
| Active Comparator: eTRE with BISC<br>participants allocated to this group are required to consume food during 0800h and 1600h as well as complete 3 sessions of BISC per week. | Behavioral: eTRE with BISC<br>* eating between 0800h and 1600h daily and completing 3 sessions of BISC per week of study duration<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Body Composition | fat mass vs. fat-free mass via BodPod | less than 5 mins | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| upper body strength test | 3-rep max bench press | < 15 mins | 
| lower body strength test | 3-rep max leg press | < 15 mins | 
| health related quality of life questionnaire | subjective feelings of well-being per participant | < 10 mins |