The Psychological and Social Impact of PCOS

Study Overview
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Brief Summary
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The aim of the study is to assess the association between the quality of life of patients with PCOS and various factors (age, BMI, socio-professional category, delay in diagnostic of PCOS, infertility, hyperandrogenism, parity, history of anxiety and depression, cycles disorders). This study will be proposed to patients known to have PCOS, during a follow-up consultation or a visit to a day hospital in the Gynaecology Department and/or a consultation in the Reproductive Medicine Department. No-objection forms will be collected at the same time. A link will be sent by e-mail to the patient to access the online questionnaire on the WEPI software and complete it after the consultation. Responses to the questionnaire will be collected progressively and stored in a secure RedCAP file.

Official Title
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The Psychological and Social Impact of PCOS

Conditions
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Polycystic Ovary Syndrome

Intervention / Treatment
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* Other: Questionnaire


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Female sex Adult patient (aged 18 or over) Able to read and write in French diagnosed at a previous consultation as having PCOS according to the Rotterdam criteria (at least 2 out of 3 criteria from: Clinical signs of hyperandrogenism (hirsutism, acne, androgenic alopecia) and/or biochemical signs of hyperandrogenism (total testosterone > 0.39 ng/mL and/or androstenedione > 1.75 ng/mL) Ovulation disorders (infertility, oligomenorrhoea or amenorrhoea or cycle length either <21 days or >35 days), Polymicrocystic ovaries on ultrasound (either 19 or more follicles measuring 2-9 mm in diameter and/or increased ovarian volume (>10 cm3) and/or increased ovarian area (> 5.5 cm²) without presence of cyst or dominant follicle.) Informed consent Exclusion Criteria: Patient with no health insurance cover Difficulties understanding or speaking French Computer (tablet/smartphone) and internet connection required. Refusal to take part in research Under court protection (guardianship/curatorship/privation of liberty)

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| PCOS patients<br> | Other: Questionnaire<br>* Questionnaire on WEPI software (secure data), with link sent by e-mail to patients included in the study, including PCOSQOL, HADS, FACT G7 et ASEX scores.<br>* Other names: Questionnaire on WEPI;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Assessment to the The Polycystic Ovary Syndrome Quality of Life scale questionnaire score | according to predefined factors (age, BMI, socio-professional category, delay in diagnosis of Polycystic Ovary Syndrome, infertility, hyperandrogenism, parity, history of anxiety and depression, cycle disorders). Mininum score: 35, maximum score: 245, A higher score means best result | Day of inclusion | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Assessment of the Hospital Anxiety and Depression Scale (HADS) questionnaire score according to predefined factors | minimun: 0 maximum: 42. A higher score means worse result | Day of inclusion | 
| Assessment of the functional Assessment of Cancer Therapy-General (FACT G7) score according to predefined factors | minimun: 0 maximum: 28 A higher score means worse result | Day of inclusion | 
| Assessment of the Arizona Sexual Experience Scale (ASEX) score according to predefined factors | minimun: 0 maximum: 30. A higher score means better result | Day of inclusion |