Whitening Efficacy and Tooth Sensitivity of Different Concentrations of Hydrogen Peroxide Photoactivated With Violet or Blue LEDs

Study Overview
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Brief Summary
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This is a randomized, controlled, double-blind and repeated-measures clinical trial evaluated the photoactivation of hydrogen peroxide gels in different concentrations with blue or violet LED in terms of whitening efficacy and tooth sensitivity.

Official Title
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Clinical Comparison of Whitening Efficacy and Tooth Sensitivity of Different Concentrations of Hydrogen Peroxide Photoactivated With Violet or Blue LEDs

Conditions
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Color, Bleaching Sensitivity

Intervention / Treatment
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* Other: 6% hydrogen peroxide gel + violet LED
* Other: 6% hydrogen peroxide gel + blue LED
* Other: 35% hydrogen peroxide gel + violet LED
* Other: 35% hydrogen peroxide gel + blue LED


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: at age 18 or older, with good general and oral health; possessing all six natural and healthy upper anterior teeth with a color shade of A2 or darker, determined by comparison with the Vita Classic scale; Exclusion Criteria: pregnant and breastfeeding women; individuals with internal tooth discoloration (tetracycline stains, fluorosis or hypoplasias); smokers, or those with veneers or restorations on the teeth in questions were excluded; gingival recession; dentin exposure; periodontal disease.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: HP6V<br>6% hydrogen peroxide gel + violet LED | Other: 6% hydrogen peroxide gel + violet LED<br>* Tooth whitening with 6% hydrogen peroxide gel (Lase Peroxide Lite, DMC, São Carlos, Brazil) activated by violet LED<br>|
| Experimental: HP6B<br>6% hydrogen peroxide gel + blue LED | Other: 6% hydrogen peroxide gel + blue LED<br>* Tooth whitening with 6% hydrogen peroxide gel (Lase Peroxide Lite, DMC, São Carlos, Brazil) activated by blue LED<br>|
| Experimental: HP35V<br>35% hydrogen peroxide gel + violet LED | Other: 35% hydrogen peroxide gel + violet LED<br>* Tooth whitening with 35% hydrogen peroxide gel (Lase Peroxide Sensy, DMC, São Carlos, Brazil) activated by violet LED<br>|
| Experimental: HP35B<br>35% hydrogen peroxide gel + blue LED | Other: 35% hydrogen peroxide gel + blue LED<br>* Tooth whitening with 35% hydrogen peroxide gel (Lase Peroxide Sensy, DMC, São Carlos, Brazil) activated by blue LED<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Color | A operator measured the color of the six upper anterior teeth using a digital spectrophotometer (VITA Easyshade V, Wilcos, Petrópolis, RJ, Brazil). | Color assessment was carried out before bleaching, 1 week after bleaching and 3 months after bleaching | 
| Bleaching Sensitivity | The degree of tooth sensitivity of patients was recorded using a visual analogue scale (VAS) from 0 to 10, where 0 represents no tooth sensitivity and 10 represents the greatest tooth sensitivity ever felt by the patient. | Assessments were carried out three times: before bleaching, immediately after bleaching, and 24 hours after bleaching. |