The Role of DLOTCA-G in the Cognitive Function Evaluation of Parkinson's Patients

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to evaluate the usefulness of Dynamic Loewenstein's Occupational Therapy and Cognitive Assessment Scale for Geriatrics (DLOTCA-G) in parkinson patients.

Detailed Description
-----------------
The purpose of this study to evaluate the usefulness of Dynamic Loewenstein's Occupational Therapy and Cognitive Assessment Scale for Geriatrics (DLOTCA-G) in the early detection of cognitive impairment in parkinson patients aged 65 and over, with and without dementia.The investigators also aimed to compare the Mini Mental State Assessment Test with DLOTCA-G.

Official Title
-----------------
The Role of Dynamic Lowenstein Occupational Therapy Cognitive Assessment-Geriatric Version (DLOTCA-G) in the Cognitive Function Evaluation of Parkinson's Patients

Conditions
-----------------
Parkinson Disease

Intervention / Treatment
-----------------
* Other: assesment of cognitive parameters with DLOTCA-G


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusıon Criteria Parkinson's patients aged 65 years and older with and without cognitive impairment (60 patients) and healthy control patients (30 patients) Hoehnn Yahr Staging between 1 and 2.5 in patients with Parkinson's diseas Confirmed by brain MRI from patients without vascular dementia who routinely attend the Parkinson's follow-up outpatient clinic At least primary school graduates In patients with Parkinson's dissease patients with cognitive impairment, MMSE below 20 in primary school education level; below 24 in secondary, high school and university education level In patients with Parkinson's disease without cognitive impairment, MMSE 20 and above in primary school education level; 24 and above in secondary, high school and university education level Exclusıon Criteria Preexisting cognitive impairment Psychiatric disorders such as psychotic disorders, mood disorders, alcohol or drug abuse Severe language dysfunction and/or bilateral limb motor dysfunction and inability to participate in clinical psychology tests, severe visual and/or auditory impairments Patients with significant cerebral atrophy or neurological vascular lesions The Geriatric Depression Scale was administered to all participants, and participants with a total score of 13 or more out of 30 points were excluded from the study.

Ages Eligible for Study
-----------------
Minimum Age: 65 Years
Maximum Age: 90 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental<br>Parkinson's disease patients with cognitive impairment | Other: assesment of cognitive parameters with DLOTCA-G<br>* All three groups were evaluated once with the DLOTCA-G, a cognitive assessment battery.<br>|
| Active Comparator<br>Parkinson's disease patients without cognıtıve impairment | Other: assesment of cognitive parameters with DLOTCA-G<br>* All three groups were evaluated once with the DLOTCA-G, a cognitive assessment battery.<br>|
| other<br>Health geriatric persons | Other: assesment of cognitive parameters with DLOTCA-G<br>* All three groups were evaluated once with the DLOTCA-G, a cognitive assessment battery.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Dynamic Lowenstein Occupational Therapy Cognitive Assessment-Geriatric Version | The Dynamic Lowenstein Occupational Therapy Cognitive Assessment is an occupational performance measurement battery designed to assess basic cognitive skills and visual perception in adults with neurological deficits. Consists 8 subtests: orientation, awareness, visual perception, spatial perception, praxis, visuomotor construction and thinking operations and memory. All subtests of DLOTCA-G are scored between 1 - 4 points. And higher scores indicate better cognitive performance. There is no cut-off value for Parkinson's patients. | Baseline (First assessment) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mini Mental State Examination | The Mini Mental State Examination is a brief screening tool that provides a quantitative assessment of cognitive impairment and to record cognitive changes over time. It consists of five subscales: orientation, memory, attention and calculation, recall and language. In the evaluation of the test, scores below 15 indicate low cognitive level, scores between 15 and 26 indicate medium cognitive level, and scores of 26 and above indicate high cognitive level. | Baseline (First assessment) | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Parkinson Disease, DLOTCA-G