Correlation Between OCT and mFERG Findings With VA After Vitrectomy Surgery for Retinal Detachment

Study Overview
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Brief Summary
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Correlation between optical coherence tomography and multifocal electroretinogram findings with visual acuity after vitrectomy surgery for Retinal detachment.

Detailed Description
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Although the anatomical success rate of vitreoretinal surgery has improved over the last decade, visual results remain compromised? Patients with macula-off retinal detachments (RDs) can have poor visual recovery, specific color vision defects, or metamorphopsia postoperatively despite successful retinal reattachment. In these cases, subtle changes in the foveal structure may be causing visual disturbances that can be difficult to identify during standard clinical examinations such as slit lamp biomicroscopy or binocular indirect ophthalmoscopy .reported a possible association between incomplete visual recovery and the presence of residual subretinal fluid (SRF) postoperatively. Optical coherence tomography (OCT) is a non-invasive technique that provides information about the morphology of the retina, and especially of the macular area in vivo. Some studies support the idea that OCT determines structural changes in the macula that are correlated with subjective visual function, including visual acuity (VA) in patients with vitrectomy for retinal detachment. Additionally, multifocal electroretinogram (m fERG) evaluation can be helpful in assessing macular function in post-vitrectomy. However, to date, there are relatively few reports concerning the combined use of OCT and m fERG for the correlation between retinal morphology and function of the macula in patients with vitrectomy for retinal detachment surgery. The purpose of our study is to determine whether a significant correlation exists between the amplitude of m fERG, visual acuity, and the morphological OCT changes by in the macula after vitrectomy for retinal detachment

Official Title
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Correlation Between Optical Coherence Tomography and Multifocal Electroretinogram Findings With Visual Acuity After Vitrectomy Surgery for Retinal Detachment

Conditions
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Retinal Detachment

Intervention / Treatment
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* Diagnostic Test: optical coherence tomography,multifocal electroretinogram. VA measurment


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients with successful vitrectomy for retinal detachment. Exclusion Criteria: The patients who had vitrectomy for reasons other than retinal detachment surgery Patients who had done scleral buckle surgery Patients with media opacity are prevented from doing retina imaging. Failed or recurrent vitrectomy surgery
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: optical coherence tomography,multifocal electroretinogram. VA measurment|retinal photography|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| CMT,BCVAand mf-ERG were recoreded in 40 eyes of 40 patintes with vitrectomy for retinal detchament surgery . | Each 10 um increase in central (CMT) associated by how increase decimal in Best corrected visual acuity and by how nV/deg2 increase multifocal electroretinogram in these eyes . | 6 months | 
| BCVA(best corrected visual acuity) | Best corrected Visual acuity measurement using Snellen's Acuity Chart and will be expressed as decimal notation | 6 Month | 
| CMT(central macualr thikness ) um | centeral macualr thikness mesurment using using optical chorent tomgraphgy | 6 month | 
| mf-ERG amplituide nV/deg2 | multifocal electroretinogram amplituide mesurement using mf-ERG machine | 6 month |