Ultrasound-Guided Internal Superior Laryngeal Nerve Block for Double-Lumen Bronchial Tube

Study Overview
=================
Brief Summary
-----------------
investigate the effectiveness and safety of ultrasound-guided bilateral internal branch of the SLN (iSLN) block for alleviating POST immediately after the operation.

Official Title
-----------------
Effect of Ultrasound-Guided Internal Superior Laryngeal Nerve Block on Sore Throat After Intubation by Double-Lumen Bronchial Tube for Thoracoscopic Surgery

Conditions
-----------------
Postoperative Sore Throat

Intervention / Treatment
-----------------
* Procedure: internal superior laryngeal nerve block
* Drug: Lidocaine 2% Injectable Solution
* Drug: Bupivacaine 0.5% Injectable Solution


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: ASA 1 to 3 Exclusion Criteria: patients who did not provide consent with a pre-existing sore throat, hoarseness and upper respiratory tract infection tracheal pathology, tracheostomy a history of psychosis, diabetes and thyroid, oral cavity or pharynx surgery known or suspected allergy to ropivacaine chronic opioid use use of nonsteroidal anti-inflammatory drug medication within 24 hours known or suspected difficult airway patients who will be supported by tube ventilator after the operation.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: control group<br>patients will undergo a thoracoscopic surgery under general anesthesia with double-lumen bronchial intubation without any special treatment. | |
| Active Comparator: experimental group<br>patients will receive US-guided iSLN block bilaterally with 2 ml of ( 0.5 ml of 2%lidocaine and 1,5 ml of 0.5% bupivacaine) on either side immediate after the operation concomitant with GA in order to undergo thoracoscopic surgery | Procedure: internal superior laryngeal nerve block<br>* A linear 4- to 12-MHz ultrasound probe will be placed in the oblique parasagittal plane to obtain an image of the hyoid bone and the thyroid cartilage. The probe will be kept parasagitally, and the following structures will be identified anteriorly to posteriorly: omohyoid muscle, sternohyoid muscle, thyrohyoid muscle, thyrohyoid membrane, superior laryngeal artery, and pre-epiglottis space. After identifying the local anatomic structure, a needle will be inserted out-plane from anterior to posterior. The muscles above the thyrohyoid membrane will be penetrated and hydrodissected; local anesthetic will be injected into the superior laryngeal nerve space. The superior laryngeal nerve space will be located between the hyoid bone (cephalad) and the thyroid cartilage (caudal) and delimited between the thyrohyoid muscle, anteriorly, and the thyrohyoid membrane and the pre-epiglottis space, posteriorly<br>Drug: Lidocaine 2% Injectable Solution<br>* 0.5 ml will be injected<br>Drug: Bupivacaine 0.5% Injectable Solution<br>* 1.5 ml will be injected<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the pain classification of postoperative sore throat | an established scoring system feom 0 to 4 | from immediate postoperative till 24 hours postoperative |