HanYang University Medical Center (HYUMC) Registry

Study Overview
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Brief Summary
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The HYUMC registry is a two-center, real-world registry of percutaneous coronary intervention in patients with coronary artery disease. From January 2012, PCI-treated patients from Hanyang University Seoul Hospitals and Hanyang University Guri Hospitals were enrolled in this registry. The aim of this registry is to examine the long-term clinical outcomes and identify predictors of adverse outcomes following percutaneous coronary intervention conducted at academic hospitals.

Detailed Description
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In the HYUMC registry, the researchers have gathered and assessed various demographic, laboratory, echocardiographic, and angiographic measurements (both on-admission and during follow-up), as well as conducted questionnaires among patients who underwent percutaneous coronary intervention. The primary focus of this registry is to examine the effects of these parameters on long-term clinical outcomes.

Official Title
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HanYang University Medical Center (HYUMC) PCI Registry

Conditions
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Coronary Artery Stenosis, Coronary Artery Disease, Blood Pressure

Intervention / Treatment
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* Device: percutaneous coronary intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Consecutive patients with CAD who underwent PCI one or more drug eluting stent (DES) with from 2012 at the Division of Cardiology of Hanyang University Seoul Hospital and Hanyang University Guri Hospital, Korea. Exclusion Criteria: second or subsequent hospitalization records of patients with multiple admissions patients who died during index hospitalization patients who treated with first-generation drug eluting stent patients with an outpatient follow-up record of less than 6 months patients with insufficient medical records.

Ages Eligible for Study
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Minimum Age: 19 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| patients with CAD undergoing PCI<br>patients with CAD undergoing PCI with second generation DES | Device: percutaneous coronary intervention<br>* patients with CAD undergoing PCI with second generation DES<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| MACCE (major adverse cardiac and cerebrovascular event) | the composite of all-cause death, myocardial infarction, stroke, or any revascularization | 10-year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| All-cause death | death from any cause | 10-year | 
| Myocardial infarction, | presence of clinical symptoms with the presence of electrocardiographic changes, or imaging evidence of new loss of viable myocardium or new regional wall motion abnormalities, in conjunction with elevated levels of cardiac biomarker above the 99th percentile upper reference limit | 10-year | 
| Stroke | neurological deficit resulting from acute focal damage to the central nervous system due to a vascular cause, requiring hospitalization, and confirmed by a neurologist through imaging findings | 10-year | 
| Any revascularization | PCI or coronary artery bypass surgery on either target or nontarget vessels | 10-year |