Enthesis Differences in Rheumatoid Arthritis and Axial Spondyloarthropathy

Study Overview
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Brief Summary
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The aim of this study is to investigate the sonographic differences in entheses in patients with Rheumatoid arthritis and Axial Spondyloarthropathy.

Detailed Description
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After recording the demographic data of the patients; 5 enthesis regions 5 enthesis sites were evaluated bilaterally as ''tricipital tendon (TT), quadricipital tendon (QT), proximal patellar tendon (PPT), distal patellar tendon (DPT), achilles tendon (AT)'' will be sonographically evaluated and the presence of hypoechogenicity , tendon thickness increase, power Doppler activity, erosion, presence of entezophyte/calcification will be investigated. The differences between the groups will then be compared.

Official Title
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Ultrasonographic Differences in Entheses in Rheumatoid Arthritis and Axial Spondyloarthropathy Patients

Conditions
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Axial Spondyloarthritis, Rheumatoid Arthritis, Enthesitis, Enthesopathy

Intervention / Treatment
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* Other: ULTRASOUND


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Rheumatoid arthritis patients identified according to the 2010 American College of Rheumatology /Europan Leage Against Rheumatism classification criteria, axial Spondyloarthrtis patients identified according to the Assessment of Spondyloarthritis classification criteria healthy controls with no history of rheumatic diseases. Exclusion Criteria: history of limb trauma and surgery in the last 3 months, metabolic disease (diabetes mellitus, hypothyroidism), malignant neoplasm, limitation of range of motion in the extremity, those who have received corticosteroid injections in the last 3 months, uncontrollable fibromyalgia.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| group 1: axial spondyloarthritis<br>SpA patients identified according to the Assessment of Spondyloarthritis classification criteria | Other: ULTRASOUND<br>* 10 enthesis areas will be evaluated in 20 minutes with ultrasound.<br>|
| group 2: Rheumatoid arthritis<br>RA patients identified according to the 2010 American College of Rheumatology/Europan Leage Against Rheumatism classification criteria | Other: ULTRASOUND<br>* 10 enthesis areas will be evaluated in 20 minutes with ultrasound.<br>|
| group:3 Healthy Control<br>healthy controls with no history of rheumatic diseases | Other: ULTRASOUND<br>* 10 enthesis areas will be evaluated in 20 minutes with ultrasound.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Ultrasound enthesis differences between the groups | triceps tendon, quadriceps tendon, proximal patellar tendon, distal patellar tendon and achilles tendons enthesitis scores differences between the groups | 2 months | 
| The relationship between ultrasound findings and disease parameters | The relationship between triceps tendon, quadriceps tendon, proximal patellar tendon, distal patellar tendon and achilles tendons enthesitis scores and Clinical disease activity index and BASDAI | 2 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Axial Spondyloarthritis,, Rheumatoid Arthritis, Enthesitis, Ultrasound