linjc16/ctgov huggingface dataset:
COVID-19 Infection

Study Overview
=================
Brief Summary
-----------------
Post-transplant patients with COVID-19 infection who attended Shenzhen No. 3 Hospital from December 2022 to February 2023, and enrolled the general population with COVID-19 infection who were hospitalized during the same period, matched by age and gender.

Detailed Description
-----------------
Data collection：Age, BMI, underlying comorbidities and other basic information were collected retrospectively from the two groups. The medical records were used to collect information about the patients' new coronavirus infection, such as the time of onset of symptoms, time of diagnosis, time of conversion and common symptoms such as fever, cough, nasal congestion and runny nose, muscle aches and pains.To compare the differences of the diagnosis and treatment of KTRs and the general population infected with Omicron

Official Title
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Comparative Study of COVID-19 Infection in Renal Transplant Recipients and Non Transplant Recipients

Conditions
-----------------
COVID-19, Renal Transplant Infection

Intervention / Treatment
-----------------
* Other: Treatment plan


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Confirmed novel coronavirus infection between December 2022 to February 2023, Exclusion Criteria: Age less than 18; failure of the transplanted kidney before the new coronavirus infection; exclusion of oral immunosuppressed and other types of organ transplant recipients from the non-renal transplant population

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Kidney Transplant Recipients Group (KTR)<br> | Other: Treatment plan<br>* Patients with different diagnoses will get different treatment options<br>|
| Non-Kidney Transplant Recipients Group（NKTR）<br> | Other: Treatment plan<br>* Patients with different diagnoses will get different treatment options<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| ICU admission or death | patients have ICU admission or death | through study completion, an average of 1 month |
A Clinical Study on Endoscopic and Histopathological Outcomes of Screening and Surveillance Colonoscopies

Study Overview
=================
Brief Summary
-----------------
The objective of this study is to collect colonoscopy data for use in the development and testing of artificial intelligence (AI) devices for colonoscopies.

Detailed Description
-----------------
The primary objective of this study is to collect colonoscopy data for use in the development and performance evaluation of AI devices. The data will be collected during routine colonoscopy procedures. Biopsy or resection will be performed if needed and all specimens will be sent for histopathological examination. The histopathological results will be recorded.

Official Title
-----------------
Collecting Real-world Data on Endoscopic and Histopathological Outcomes of Screening and Surveillance Colonoscopies for the Development of a CAD (Computer Aided Detection) System: A Prospective, Multicenter, Post-market Investigation

Conditions
-----------------
Colonic Polyp

Intervention / Treatment
-----------------
* Device: Colonoscopy


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients aged 18 years or older Patients who have signed a written consent form from their voluntary decision after receiving thorough explanation on this study and fully understanding the explanation prior to participation in the study Patients who plan to receive colonoscopy procedure and meet any of the following conditions: Colon cancer screening, post-polypectomy surveillance, patients who are advised by a physician to take a colonoscopy exam Exclusion Criteria: Patients for whom endoscopic submucosal dissection is planned Patients for whom polypectomy is difficult to perform due to antithrombotic therapy received etc. Patients who have to receive an urgent colonoscopy procedure Patients who underwent total colectomy of the large intestine Patients who are judged by a physician to be contraindicated for colonoscopy procedures Patients who have participated in another clinical study within the last 30 days

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Device: Colonoscopy|Screening or surveillance colonoscopy|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Videos and still images of the colonoscopy | Narrow band imaging (NBI) images and white-light images, video recordings of the colonoscopy | during the procedure |
Determining Patterns In Trial Experiences of Recurrent Prostate Cancer Patients

Study Overview
=================
Brief Summary
-----------------
Clinical studies, with a dedicated focus on recurrent prostate cancer, play a pivotal role in evaluating the safety and effectiveness of novel treatments for this condition. These trials serve as essential tools to determine whether new medications outperform traditional therapies, providing substantial evidence to endorse their broader utilization. It will also try to analyze data from the perspective of different demographic groups to check for recurring trends which might yield insights for the sake of future patients with recurrent prostate cancer.

Official Title
-----------------
Investigating the Dynamics of Patient Engagement and Trends in Participation in Recurrent Prostate Cancer Clinical Trials

Conditions
-----------------
Recurrent Prostate Cancer

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patient is at least 18 years of age Diagnosis of recurrent prostate cancer Ability to understand and the willingness to sign a written informed consent document Exclusion Criteria: Enrolled in another research study Patients with psychiatric illness/social situations that would limit compliance with study requirements Inability to provide written informed consent

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
Male

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of patients who decide to participate in a recurrent prostate cancer clinical research |  | 3 months | 
| Rate of patients who remain in recurrent prostate cancer clinical research to trial completion |  | 12 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Recurrent Prostate Cancer
Social Determinants of Health in Hepatobiliary Cancer Patients

Study Overview
=================
Brief Summary
-----------------
This study evaluates barriers to receiving care and risks associated with developing cancer among patients diagnosed with hepatobiliary cancer.

Detailed Description
-----------------
PRIMARY OBJECTIVE: I. To characterize the social determinants of health - and specifically travel-limiting access to cancer care but also other issues, such as trouble in finding childcare, joblessness, and limited education - among Southeast Asian Americans with hepatobiliary cancers, exposure risk including aflatoxin and viral hepatitis among other exposures. OUTLINE: This is an observational study. Patients complete a questionnaire, undergo blood sample collection and have their medical records reviewed on study.

Official Title
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Social Determinants of Health in Hepatobiliary Cancer Patients

Conditions
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Malignant Hepatobiliary Neoplasm

Intervention / Treatment
-----------------
* Other: Non-Interventional Study


Participation Criteria
=================
Eligibility Criteria
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Inclusion Criteria: Patients 18+ year of age with hepatobiliary cancers Exclusion Criteria: Patients under 18 years of age

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Observational<br>Patients complete a questionaire, undergo blood sample collection and have their medical records reviewed on study. | Other: Non-Interventional Study<br>* Non-interventional study<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Percentage of patients reporting transportation barriers that affect medical care | Estimated using Social Determinants of Health Screening Tool designed by the American Academy of Family Medicine, by the proportion of patients who respond yes to the question, Do you put off or neglect going to the doctor because of distance or transportation?. | Baseline; up to 2 years |
Improvement of ARDS Ventilation-perfusion Matching by Prone Positioning Assessed by EIT

Study Overview
=================
Brief Summary
-----------------
Acute Respiratory Distress Syndrome (ARDS) is a highly lethal disease with limited treatment options. In recent years, prone position ventilation has been shown to improve the mortality rate and lung injury of ARDS patients by promoting lung recruitment, improving ventilation/perfusion (V/Q) ratio, enhancing respiratory system compliance, promoting sputum drainage, and effectively avoiding overinflation of the dorsal lung. Electrical Impedance Tomography (EIT) technology has been used to evaluate the effect of prone position ventilation on lung V/Q matching, and some studies have confirmed that prone position ventilation can improve lung V/Q matching and oxygenation index. However, previous studies were mostly case reports or small-sample physiological studies that lacked dynamic changes in lung V/Q matching during repeated prone position ventilation. Therefore, this study hypothesizes that prone position ventilation can increase lung V/Q matching in ARDS patients, and its improvement is correlated with changes in oxygenation index, invasive ventilation time, and patient prognosis. Repeated prone position ventilation can maintain lung V/Q matching at a higher level, no longer affected by changes in body position, which can accelerate pulmonary function recovery and improve the prognosis of ARDS patients.

Official Title
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Improvement of Acute Respiratory Distress Syndrome Ventilation-perfusion Matching by Prone Positioning Assessed by Electrical Impedance Tomography

Conditions
-----------------
Acute Respiratory Distress Syndrome, Prone Position, Electrical Impedance Tomography

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age ≥ 18 years old; meet the diagnostic criteria of Berlin's definition for ARDS; invasive ventilation time < 48h; PaO2/FiO2 < 150mmHg. Exclusion Criteria: Contraindication to the prone position; Contraindication to the EIT; Hemodynamically unstable; Patients with hypernatremia; Patients have received extracorporeal membrane oxygenation treatment.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| PaO2/FiO2 | PaO2/FiO2 in patients after 1 hour of prone position. | After 1 hour of prone position. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Ventilator-free days | Days without receiving invasive ventilation at day 28. | At day 28 after enrollment. |
The China CardioMyopathy Registry Study

Study Overview
=================
Brief Summary
-----------------
Cardiomyopathy is the most common inherited cardiovascular disease, showing family aggregation, so it has a huge psychological and economic burden on family members. Studying the clinical characteristics of patients with cardiomyopathy is helpful for further diagnosis, treatment and management, which has important clinical and social significance.

Detailed Description
-----------------
In this study, patients hospitalized with cardiomyopathy as the primary discharge diagnosis in China are recruited prospectively after informed consent was given. The investigator will collect the baseline clinical characteristics of the patients at enrollment, including comprehensive physical examination, laboratory testing of blood and urine, electrocardiography, 24-hour Holter, echocardiography, MRI and other examinations if necessary. Data are collected with the use of case report forms (CRFs) and are entered into a web-based system. A 6 mL venous blood sample is obtained from consenting patients. Each participant is scheduled to be followed up by telephone every 12 months after admission to hospital.

Official Title
-----------------
The China CardioMyopathy Registry Study

Conditions
-----------------
Cardiomyopathies

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with primary discharge diagnosis meeting one of the following subtypes of cardiomyopathy were enrolled, including HCM, DCM, ACM, RCM, left ventricular non-compaction, cardiac amyloidosis, Fabry disease, Pompe disease, Danon disease, and PRKAG2 cardiac syndrome. Exclusion Criteria: Patients who refuse to sign the informed consent or decline follow-up.

Ages Eligible for Study
-----------------
Minimum Age: 16 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| number of participants with cardiovascular deaths | including sudden cardiac death and deaths due to heart failure and stroke | an average of 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| number of participants with heart failure | progress to level III or IV in New York Heart Association class | an average of 1 year | 
| number of participants with stroke | including cerebral infraction and hemorrhage | an average of 1 year | 
| number of participants with myocardial infarction | including ST-segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction | an average of 1 year | 
| number of participants with all-cause deaths | including deaths due to any causes | an average of 1 year |
Cohort Study in Fujian Province

Study Overview
=================
Brief Summary
-----------------
In this study, Chinese residents aged 35 to 75 years old were recruited from Fujian Province. Physical examination, questionnaire survey and biological sample collection were performed at baseline, and at least 4 years of follow-up were conducted. Information on newly discovered cardiovascular metabolic illnesses and comorbidities was collected during follow-up, and repeated surveys similar to baseline were conducted. To explore the relationship between environment, diet and lifestyle and the risk of cardiovascular metabolic diseases and concomitant disorders.

Official Title
-----------------
Fujian Cohort Study of cARdiomEtabolic Disease and Comorbidity(Fu-CARE)

Conditions
-----------------
Chronic Disease

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Aged 35-75, having lived in Fuzhou, Putian, Quanzhou, Nanping, Xiamen, Zhangzhou, Longyan, Sanming, or Ningde in Fujian Province for more than 6 months. Exclusion Criteria: Anyone diagnosed with coronary heart disease, stroke, or cancer. Anyone with a severe disability who is unable to participate in the study.

Ages Eligible for Study
-----------------
Minimum Age: 35 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Coronary Disease | It is a form of myocardial ischemia (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. At the follow-up, the outcomes of coronary events were acquired. Coronary CTA examination and coronary angiography were the primary measuring modalities. | 5 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| other metabolic diseases | Including hypertension, stroke, diabetes, impaired glucose tolerance, obesity, cancer, chronic obstructive pulmonary disease and chronic kidney disease. These disorders were diagnosed using international standards, and the necessary information was gathered during face-to-face follow-up. | 5 years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Cardiovascular and metabolic disease comorbidity
Multimodal Noninvasive Assessment of Peripheral Circulation in Chronic Limb-threatening Ischemia

Study Overview
=================
Brief Summary
-----------------
Assessment of a novel diagnostic method for screening and diagnosing chronic limb-threatening ischemia (CLTI). Using hyperspectral and thermal imaging, the perfusion and oxygenation in the lower limbs will be studied in healthy and unhealthy individuals.

Official Title
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Evaluation of Lower Limb Angiosome Perfusion and Oxygenation Using Thermal and Hyperspectral Imaging

Conditions
-----------------
Chronic Limb Threatening Ischemia

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: for CLTI patients age >50 for age control group age >50 and not diagnosed with cardiovascular diseases. 0.9 < ABI < 1.3 for healthy group 18 <= age <= 50 and no history of cardiovascular disease volunteering for study Exclusion Criteria: inability to give informed consent denial

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Unhealthy group<br>Individuals with CLTI | |
| Age control group<br>Healthy individuals over the age of 50 | |
| Healthy group<br>Healthy and young individuals | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Perfusion in lower limb angiosomes assessed by thermal imaging | Thermal imaging will be used to assess the perfusion in the lower limbs. The lower limb can be divided into six angiosomes, which can then be used to assess thermal patterns. Healthy and unhealthy feet will present with different thermal patterns and other changes in thermographs. | 45 minutes during the procedure starting from the first measurement and ending after the last measurement | 
| Oxygenation in lower limb angiosomes assessed by hyperspectral imaging. | Hyperspectral imaging can be used in the assessment of oxygenation in the lower limb angiosomes. Based on hyperspectral imaging, oxygenation maps can be generated and then analyzed. Differences between the oxygenation maps of healthy and unhealthy patients will be established. | 45 minutes during the procedure starting from the first measurement and ending after the last measurement | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
hyperspectral imaging, thermal imaging, angiosomes, CLTI, diabetes
Correlation Between EPB Entrapment Test and Ultrasound Wrist Findings in Patients With deQuervain's Disease

Study Overview
=================
Brief Summary
-----------------
The goal of this observational study is to learn about the correlation between EPB entrapment test and ultrasound wrist findings in patients with deQuervain's disease The main questions it aims to answer are: if correlation exist between EPB entrapment test and ultrasound wrist findings in patients with deQuervain's disease ? if the the correlation aid in deciding management of patients with deQuervain's disease Participants will be subjected to EPB entrapment test ultrasound examination of wrist

Official Title
-----------------
Correlation Between EPB Entrapment Test and Ultrasound Wrist Findings in Patients With deQuervain's Disease

Conditions
-----------------
De Quervain Disease

Intervention / Treatment
-----------------
* Diagnostic Test: ultrasound examination of wrist


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age >18 Radial side wrist pain Finkelstein test positive Failure of non surgical treatment Exclusion Criteria: • Patients who underwent Previous surgical release

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: ultrasound examination of wrist|musculoskeletal ultrasound examination of affected wrist|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| EPB entrapment test | comparing the pain elicited during resisted thumb MCP joint abduction and resisted thumb MCP joint extension | 1 day | 
| Ultrasound examination of wrist | musculoskeletal ultrasound of affected wrist is done for examining the anatomical variations of first extensor compartment | 1 day | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
de quervain's disease, anatomical variations, EPB entrapment test