The Safety and Efficacy of an Oral Superfruits Supplement

Study Overview
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Brief Summary
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This study is conducted to evaluate the safety and effectiveness of an oral superfruits supplement for skin brightening and wrinkle reduction. Superfruits are reported to have high bioactive compounds with beneficial effects on human health. The study duration is 12 weeks and the skin assessment will be carried out at baseline, week 2, week 6 and week 12. The participants will consume the supplement for 6 weeks and at week 12, final skin assessment will be conducted. The main questions this study aims to answer are: The skin brightening effect of the oral superfruits supplement. The effect of the oral superfruits supplement on wrinkle reduction. To observe any adverse effect occurrence with the consumption of the oral superfruits supplement.

Official Title
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The Safety and Efficacy of an Oral Superfruits Supplement for Skin Brightening and Wrinkle Reduction

Conditions
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Healthy

Intervention / Treatment
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* Other: Other: Oral superfruits supplement


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Malaysian citizen Male and female (age 20-60 years old) Exclusion Criteria: Participant who taking any dietary supplements for the past 4 weeks which can affect the study results Participant who are on contraceptive pills for the past 3 months Participant who undergo cosmetics treatments such as botox, filler and laser and light treatment within the last 3 months Pregnant or plans to get pregnant and breastfeeding women

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Oral superfruits supplement<br>Participants will consume oral superfruits supplement once daily for 6 weeks. | Other: Other: Oral superfruits supplement<br>* The supplement contain superfruits that are beneficial for human health<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes in skin tone from baseline and at week 2, week 6 and week 12 after consumption of the superfruits supplement | Skin tone will be assessed using JANUS III skin analyzer | Baseline, week 2, week 6 and week 12 | 
| Changes in skin wrinkles from baseline and at week 2, week 6 and week 12 after consumption of the superfruits supplement | Skin wrinkles will be assessed using JANUS III skin analyzer and Wrinkle Severity Rating Scale (WSRS). For WSRS, dermatologists will evaluate participants' wrinkles based on 5-point photonumeric rating scale that will objectively evaluate the severity of crow's feet at rest (static) and with a smiling expression (dynamic). The scale scores are 0 for no wrinkles, 1 for very fine wrinkles, 2 for fine wrinkles, 3 for moderate wrinkles, and 4 for severe wrinkles. | Baseline, week 2, week 6 and week 12 | 
| Adverse effect after consumption of the superfruits supplement | Based on adverse effect occurrence on participants that occur during study period (12 weeks) | Week 12 |