Oral Mucosal Pressure Injury in ICU Patients With Oral Tracheal Intubation

Study Overview
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Brief Summary
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In this study, based on the conceptual framework of Pressure Injurie development, the risk factors for pressure injury in critically ill patients provided by the latest guidelines, and combined with the current relevant studies on mucosal pressure injury, we prospectively observed and collected clinical data related to tracheal intubation patients in the ICU, analyzed the risk factors for the occurrence of oral MPI, and established a risk prediction model to help clinical and nursing staff to detect and actively prevent oral MPI at an early stage The study aims to improve the quality of nursing management, enhance the level of nursing services and improve patient satisfaction.

Official Title
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Construction of Risk Prediction Model for Oral Mucosal Pressure Injury in ICU Patients With Oral Tracheal Intubation

Conditions
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Oral Mucosal Pressure Injury

Intervention / Treatment
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* Device: endotracheal tube material,Bite block Material


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age ≥ 18 years; Duration of ICU admission ≥ 48h. Exclusion Criteria: radiotherapy oral mucositis; Pressure injury to the mucosa, oral ulcers and erosions from other causes already present prior to tracheal intubation; Patients undergoing oral surgery; those who have been brought in from outside the hospital for >48h for transoral tracheal intubation; Common oral ulcers (not pressure/friction generated).

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| endotracheal tube material<br>One group of patients used a spring-loaded endotracheal tube and the other group used a PVC tube. | Device: endotracheal tube material,Bite block Material<br>* Exposure factors associated with tracheal intubation in patients that may influence the occurrence of oral mucosa pressure injurie, such as the material and fixation of the tracheal tube, the patient's own nutrition, the level of tissue perfusion and relevant treatment factors.<br>* Other names: Duration of tracheal intubation;|
| Bite block Material<br>One group of patients used hard bite block and the other group used soft bite block | Device: endotracheal tube material,Bite block Material<br>* Exposure factors associated with tracheal intubation in patients that may influence the occurrence of oral mucosa pressure injurie, such as the material and fixation of the tracheal tube, the patient's own nutrition, the level of tissue perfusion and relevant treatment factors.<br>* Other names: Duration of tracheal intubation;|
| Moisture of oral mucosa<br>One group of patients had moist oral mucosa after entering the ward and the other group had dry oral mucosa. | Device: endotracheal tube material,Bite block Material<br>* Exposure factors associated with tracheal intubation in patients that may influence the occurrence of oral mucosa pressure injurie, such as the material and fixation of the tracheal tube, the patient's own nutrition, the level of tissue perfusion and relevant treatment factors.<br>* Other names: Duration of tracheal intubation;|
| serum albumin level<br>One group of patients had normal serum albumin level at the first blood sample analysis after tracheal intubation and the other group was abnormal. | Device: endotracheal tube material,Bite block Material<br>* Exposure factors associated with tracheal intubation in patients that may influence the occurrence of oral mucosa pressure injurie, such as the material and fixation of the tracheal tube, the patient's own nutrition, the level of tissue perfusion and relevant treatment factors.<br>* Other names: Duration of tracheal intubation;|
| mean arterial pressure level<br>One group of patients had normal mean arterial pressure leve after entering the ward and the other group was abnormal. | Device: endotracheal tube material,Bite block Material<br>* Exposure factors associated with tracheal intubation in patients that may influence the occurrence of oral mucosa pressure injurie, such as the material and fixation of the tracheal tube, the patient's own nutrition, the level of tissue perfusion and relevant treatment factors.<br>* Other names: Duration of tracheal intubation;|
| blood lactate level<br>One group of patients had normal blood lactate levels at the first blood sample analysis after tracheal intubation and the other group was abnormal. | Device: endotracheal tube material,Bite block Material<br>* Exposure factors associated with tracheal intubation in patients that may influence the occurrence of oral mucosa pressure injurie, such as the material and fixation of the tracheal tube, the patient's own nutrition, the level of tissue perfusion and relevant treatment factors.<br>* Other names: Duration of tracheal intubation;|
| constraint<br>One group of patients was constrained during follow-up and the other group was not constrained. | Device: endotracheal tube material,Bite block Material<br>* Exposure factors associated with tracheal intubation in patients that may influence the occurrence of oral mucosa pressure injurie, such as the material and fixation of the tracheal tube, the patient's own nutrition, the level of tissue perfusion and relevant treatment factors.<br>* Other names: Duration of tracheal intubation;|
| sedation<br>One group of patients was sedated during follow-up and the other group was not sedated. | Device: endotracheal tube material,Bite block Material<br>* Exposure factors associated with tracheal intubation in patients that may influence the occurrence of oral mucosa pressure injurie, such as the material and fixation of the tracheal tube, the patient's own nutrition, the level of tissue perfusion and relevant treatment factors.<br>* Other names: Duration of tracheal intubation;|
| prone position<br>One group of patients had a prone position performed during follow-up and the other group did not. | Device: endotracheal tube material,Bite block Material<br>* Exposure factors associated with tracheal intubation in patients that may influence the occurrence of oral mucosa pressure injurie, such as the material and fixation of the tracheal tube, the patient's own nutrition, the level of tissue perfusion and relevant treatment factors.<br>* Other names: Duration of tracheal intubation;|
| Duration of tracheal intubation<br>Dichotomous grouping of the duration of tracheal intubation according to the results of the study. | Device: endotracheal tube material,Bite block Material<br>* Exposure factors associated with tracheal intubation in patients that may influence the occurrence of oral mucosa pressure injurie, such as the material and fixation of the tracheal tube, the patient's own nutrition, the level of tissue perfusion and relevant treatment factors.<br>* Other names: Duration of tracheal intubation;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| oral mucosal pressure injury | Whether oral mucosal pressure injury occurred during the follow-up period | up to 2 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Intensive Care Units, Intubation, Intratracheal, Mucosal Pressure Injury, Prediction Model