Foveal Sparing ILM Peeling With ILM Flap Transposition

Study Overview
=================
Brief Summary
-----------------
Foveal sparing internal limiting membrane (ILM) peeling with ILM flap transposition over the macular hole combines the benefits of foveal sparing ILM peeling with ILM flap techniques. Aim of this study is to retrospectively examine the rate of postsurgical macular hole closure, development of central atrophy in the foveal area, and improvement of best corrected distant visual acuity in a group of patients having undergone foveal sparing ILM peeling with ILM flap transposition for macular hole repair.

Detailed Description
-----------------
Idiopathic full thickness macular holes lead to central defects in the visual field and to deterioration of the visual acuity. Introduction of internal limiting membrane (ILM) Peeling techniques lead to significant increase in closure rates of the macular holes. Foveal sparing ILM peeling represents a surgical technique for macular hole repair with less surgical trauma with high closure rates of the macular hole, compared to classic ILM Peeling [Ho et al. 2014, Murphy et al 2019]. The combination of foveal sparing ILM Peeling with the established ILM flap techniques [Michalewska et al 2010 und 2015] offers the potential of better improvement in postsurgical visual acuity with the high closure rates, due to ILM flaps. Aim of this study is to retrospectively examine the rate of postsurgical macular hole closure, development of central atrophy in the foveal area, and improvement of best corrected distant visual acuity in a group of patients having undergone foveal sparing ILM peeling with ILM flap transposition for macular hole repair.

Official Title
-----------------
Foveal Sparing ILM Peeling With ILM Flap Transposition

Conditions
-----------------
Full Thickness Macular Hole

Intervention / Treatment
-----------------
* Other: retrospective data analysis


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Vitrectomy with foveal sparing ILM peeling with ILM flap transposition in the time period from 1.10.2020 to 8.7.2022 Age 18 and older Idiopathic full thickness macular hole as indication for surgery Full follow-up, including visual acuity testing and OCT preoperative, and 3 months after surgery. Exclusion Criteria: Age <18 years

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| study group<br>retrospective data analysis of patients that underwent after foveal sparing ILM peeling with ILM flap transposition for macular hole repair | Other: retrospective data analysis<br>* Macular hole closure rate, visual acuity and OCT<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| macular hole closure rate | postsurgical closure of macular holes is examined from routine postsurgical optical coherence tomography (OCT) imaging | up to 3 months after surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| visual acuity | visual acuity before and 3 months after surgery is examined | 3 months | 
| OCT | measurements of macular hole diameters from presurgical OCTs and restoration of the ellipsoid zone (EZ) 3 months after surgery is analysed | 3 months |