Evaluation of Hereditary Cancer Educational Videos

Study Overview
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Brief Summary
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To learn if educational videos can help participants be more informed about hereditary cancers (ones that run in the family).

Detailed Description
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Primary Objective Determine the impact of educational videos on: Participant's hereditary cancer knowledge. Participant's confidence to share hereditary cancer information with family members. Secondary Objective Determine impact of educational videos on participant's confidence to undergo hereditary cancer screening. Identify opportunities to tailor and improve the educational video's content, style, and understandability per participant preferences and feedback.

Official Title
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Evaluation of Hereditary Cancer Educational Videos

Conditions
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Hereditary Cancer

Intervention / Treatment
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* Behavioral: Interview Study
* Behavioral: Survey Study


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Participants of The Harris Health System Lyndon B. Johnson (LBJ) Hospital outpatient oncology clinics (i.e., Gynecologic Oncology, Medical Oncology). 18 years of age or older. Speaks and/or reads English or Spanish. Has a pathogenic or likely pathogenic variant (mutation) in BRCA1, BRCA2, MLH1, MSH2, MSH6, PMS2, and/or EPCAM on germline genetic testing. Has a documented genetic testing results disclosure encounter (i.e. telephone call, follow-up appointment). Exclusion Criteria: No longer receives outpatient care at LBJ Hospital at time of recruitment. Has only a variant of uncertain significance in BRCA1, BRCA2, MLH1, MSH2, MSH6, PMS2, and/or EPCAM. Has only a pathogenic or likely pathogenic variant in gene other than BRCA1, BRCA2, MLH1, MSH2, MSH6, PMS2, or EPCAM. Is unwilling, unable, or requires a legally authorized representative to provide informed consent.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Interview Study<br>In the interview study, participants will watch the video, then complete an interview. This will take about 50 minutes. | Behavioral: Interview Study<br>* All study participants will have the following demographic information collected from their medical records: Sex (Male/Female/Other) Date of birth Preferred language (English/Spanish) Health insurance status (for example: private insurance, HCHD gold card) Cancer diagnosis (if yes: cancer type/organ, date of pathology diagnosis) Genetic testing result (gene with pathogenic/likely pathogenic variant) Date of genetic testing result Date of documented result disclosure.<br>|
| Survey Study<br>In the survey study, participants will complete a survey about your education and complete a quick test about your knowledge of hereditary cancer. Participants will then watch the video. complete another survey similar to the one before the video. This should take about 30 minutes. | Behavioral: Survey Study<br>* All study participants will have the following demographic information collected from their medical records: Sex (Male/Female/Other) Date of birth Preferred language (English/Spanish) Health insurance status (for example: private insurance, HCHD gold card) Cancer diagnosis (if yes: cancer type/organ, date of pathology diagnosis) Genetic testing result (gene with pathogenic/likely pathogenic variant) Date of genetic testing result Date of documented result disclosure.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Hereditary Cancer Multidimensional Measure of Informed Choice Questionnaires | Hereditary Cancer Multidimensional Measure of Informed Choice (MMIC) Knowledge Score scale: (1-8) true or false | through study completion; an average of 1 year |