Improvements by a Protein-Rich Plant-Based Diet and Resistance Exercise Program for Active Ageing

Study Overview
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Brief Summary
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High-protein intake and physical activity are important approaches to preserve muscle mass. Consuming high levels of high-quality proteins to preserve muscle mass is challenging with a plant-based diet. The healthy, older participants will follow a twelve-week high-protein vegetarian diet or high-protein omnivorous diet both in combination with a resistance training program. The change in protein intake and muscle mass will be assessed.

Official Title
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Improvements by a Protein-Rich Plant-Based Diet and Resistance Exercise Program for Active Ageing

Conditions
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Protein Intake

Intervention / Treatment
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* Other: Dietary and exercise intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Aged 55 years or older BMI 18.5-30 kg/m2 Living independently Ability and willingness to comply with the protocol Written an informed consent Consent of the study physician Exclusion Criteria: Alcohol abuse (more than 14 glasses per week (women) or more than 21 glasses per week (men)) or drug abuse in the opinion of the study physician (CBS et al., 2017) Inability to understand the Dutch language Cognitive impairment (MMSE more than 25) Diagnosed chronic disease that may interfere with protocol (e.g., cardiovascular, gastrointestinal, neurological, known renal diseases (eGFR more than 60 mL/min (Levey &amp;amp; Coresh, 2012), and/or diabetes) Current enrolment in an exercise program or other intervention study Planned a holiday during the intervention period and is unable to attend training sessions for more than 1 week

Ages Eligible for Study
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Minimum Age: 55 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: High-Protein Vegetarian Diet<br>High-protein vegetarian diet (no meat/fish) | Other: Dietary and exercise intervention<br>* The healthy older adults will follow a twelve-week high-protein vegetarian diet or high-protein omnivorous diet both in combination with a resistance exercise program. All participants will receive blended dietary counselling. Blended dietary counselling is based on tele-coaching and face-to-face coaching performed by dieticians.<br>|
| Active Comparator: High-Protein Omnivorous Diet<br>High-protein omnivorous diet | Other: Dietary and exercise intervention<br>* The healthy older adults will follow a twelve-week high-protein vegetarian diet or high-protein omnivorous diet both in combination with a resistance exercise program. All participants will receive blended dietary counselling. Blended dietary counselling is based on tele-coaching and face-to-face coaching performed by dieticians.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Protein intake | Protein intake | Three months |