Comparison of Erector Spinae Block and Combined Deep and Superficial Serratus Anterior Plane Block

Study Overview
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Brief Summary
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Objective: The authors hypothesized that combined deep and superficial serratus anterior plane block (SAPB) is as effective as erector spinae plane block (ESPB) for intraoperative and postoperative analgesia for video-assisted thoracoscopic surgery. Design: A prospective randomized controlled study. Participants: Adult patients undergoing elective video-assisted thoracoscopic surgery. Interventions: Preoperative SAPB or ESPB implementation.

Detailed Description
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Plane blocks implemented on preoperative course on 35 patients for each group. Postoperative Visual Analogue Scale (VAS) scores (0-10), intraoperative and postoperative analgesic consumption was measured using Mann-Whitney test. In the postoperative phase, opioid side effects, complications related to plane blocks, mobilization time and length of hospital stay was recorded and measured.

Official Title
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Comparision of the Effects of Ultrasound-guided Erector Spinae Block and Combined Deep and Superficial Serratus Anterior Plane Block on Perioperative Analgesia for Video-assisted Thoracoscopic Surgery.

Conditions
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Analgesia, Pain, Postoperative, Thoracic, Anesthesia

Intervention / Treatment
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* Procedure: erector spinae plane block
* Procedure: combined deep and superficial serratus anterior plane block


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: American Society of Anaesthesiologists (ASA) classification I-II scheduled for elective VATS Exclusion Criteria: Patients who did not give consent Local anaesthetic allergy Known or suspected coagulopathy İnfection at the injection site History of thoracic surgery Severe cardiovascular disease Hepatic or renal insufficiency (glomerular filtration rate <15 ml/min/1.73 m2) Severe neurological or psychiatric disorders Chronic opioid use

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: randomized, controlled
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: erector spinae plane block<br>Plane blocks implemented on preoperative course on 35 patients for group. | Procedure: erector spinae plane block<br>* Erector spinae plane block was implemented on preoperative course on 35 patients. Intraoperative analgesic (Fentanyl) consumption was measured for intraoperative effects of the erector spinae plane block. Postoperative Visual Analogue Scale (VAS, from 0 to 10) scores and postoperative analgesic (Morphine) consumption was measured using Mann-Whitney test.<br>|
| Active Comparator: combined deep and superficial serratus anterior plane block<br>Plane blocks implemented on preoperative course on 35 patients for group. | Procedure: combined deep and superficial serratus anterior plane block<br>* Combined deep and superficial serratus anterior plane block was implemented on preoperative course on 35 patients. Intraoperative analgesic (Fentanyl) consumption was measured for intraoperative effects of the erector spinae plane block Postoperative Visual Analogue Scale (VAS, from 0 to 10) scores and postoperative analgesic (Morphine) consumption was measured using Mann-Whitney test.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| postoperative analgesic effects | The primary outcome is compare the postoperative analgesic effects of SAPB and ESPB applied under USG guidance before surgery in patients scheduled for VATS using VAS (Visual Analogue Scale from 0 to 10). | first 48 hours | 
| intraoperative analgesic effects | The primary outcome is compare the intraoperative analgesic effects of SAPB and ESPB applied under USG guidance before surgery in patients scheduled for VATS by measuring perioperative fentanyl consumption in both groups. | intraoperative phase | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| side effects | The secondary aim was to compare the opioid side effects. Patients were informed about opioid side effects and asked whether side effects were present. | first 48 hours | 
| complications | The secondary aim was to compare the complications related to the applied block. Patients were examined and evaluated for any complications related to the block. | first 48 hours | 
| mobilization | The secondary aim was to compare the mobilization time | first 48 hours | 
| stay of hospital | length of stay in the recovery unit and hospital | first 4 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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serratus anterior plane block, video-assisted thoracoscopic surgery, erector spinae block, postoperative analgesia