Efficacy of Virtual Reality Based Exercise Regimes on Kinesiophobia, Pain and Functional Disability in Patients With Knee Osteoarthritis

Study Overview
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Brief Summary
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Knee Osteoarthritis is one of the most prevalent degenerative conditions in Pakistan. Although a variety of Physical therapy treatments have been proven to be beneficial in patients with early stages of knee Osteoarthritis. However, a few secondary impairments like Kinesiophobia which is the fear of movement have been unaddressed. Usually after conventional physical therapy, patients find immediate or short-term relief and that leads to cessation of follow up sessions. In situations like these, kinesiophobia is the greatest threat to mobility and can eventually effect quality of life by decreasing functional disability.

Official Title
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Efficacy of Virtual Reality Based Exercise Regimes on Kinesiophobia, Pain and Functional Disability in Patients With Knee Osteoarthritis

Conditions
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Knee Osteoarthristis

Intervention / Treatment
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* Procedure: Conventional Physical Therapy for Knee Osteoarthriths
* Procedure: Virtual Reality-Based Therapeutic Exercise regimes


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients with unilateral knee OA involving mediolateral compartment Knee OA grade 2 Aged 40-65 years Both Male and Female NPRS value greater than Exclusion Criteria: Patients with history of History of systemic disorder (e.g., rheumatoid arthritis, ankylosing spondylitis). History of malignancy. History of trauma. Previous knee surgery. Congenital musculoskeletal deformity (e.g., scoliosis, kyphosis). Patients with history of fracture Patients with history of Chondropatella Malacia

Ages Eligible for Study
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Minimum Age: 45 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: This is a randomized controlled trial having two groups. One group will receive conventional physical therapy along with Natural apophyseal glides and the second will receive Natural Apophyseal Glides in addition to cranial base release with conventional physical therapy. Both groups will be recruited concurrently.
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Conventional Physical Therapy Regime for Knee Osteoarthrithis<br>Pt will receive conventional therapy targeting stretching and stretching of knee musculature in combination with electrotherapy for pain modulation. Frequency : 2-3 times for a duration of 6 weeks Pt will be guided home plan based exercises. | Procedure: Conventional Physical Therapy for Knee Osteoarthriths<br>* Participants of Group A will receive the conventional physical therapy for Knee Osteoarthistis for a duration of 6 weeks atleast 2 times a week<br>|
| Experimental: Virtual reality Based Therapeutic Exercise Regimes<br>VR-based therapeutic exercise regimes utilizing Xbox, that focus on different activities like Partial squatting, lunges, side lunge, calf raises, and hamstring curls. Gaming exercises begin will an easy warm up round and get challenging with different rounds of each game as the patient progresses to week 6. Frequency: 2-3 times for a duration for 6 weeks Pt will be guided home plan based exercises | Procedure: Virtual Reality-Based Therapeutic Exercise regimes<br>* Participants of Group B will receive Virtual Reality Based therapeutic exercises on the Xbox. The difficulty level of the games will progess each week. The duration of training will also also progress at treatment week progresses. Frequency: 2-3 times a week for 6 weeks. Minimum 12 sessions in total.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Kinesiophobia | Kinesiophobia will be measured using the Tampa Scale of Kinesiophobia | 6 weeks | 
| Pain intensity | Will be Measured using the Numeric Pain rating scale | 6 weeks | 
| Functional Disability | Will be measured using WOMAC Osteoarthritis Index | 6 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Range of Motion, Proprioception