Imaging of Corneal and Crystalline by Near Infrared Retro-illumination

Study Overview
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Brief Summary
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Retroillumination photography is difficult. The reflections on the cornea and the lens are constant and prevent from obtaining a complete and clear image. Study team have modified a slit lamp intended to photograph the anterior segment of the eye in retroillumination by using a light source in the near infrared (780 nm), and a process which eliminates the reflections.

Official Title
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Imaging of Corneal and Crystalline by Near Infrared Retro-illumination

Conditions
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Eye Diseases

Intervention / Treatment
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* Device: Retro-illuminator


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patient with corneal pathology, crystalline pathology, or pigmentary glaucoma with transilluminable iris. In case of bilateral disease, both eyes will be photographed Patient having received an instillation of eye drops to dilate the pupil of the eye to be photographed (or of both eyes). Exclusion Criteria: Major blepharospasm Poor or no pupillary dilation: patient with allergy or intolerance to eye drops used for pupillary dilation, refusal of pupillary dilation Pregnant or breastfeeding patient Person under legal protection

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Interventional Model Description: Exploratory pilot study
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Patient with corneal pathology, crystalline pathology, or pigmentary glaucoma<br>Patient with corneal pathology, crystalline pathology, or pigmentary glaucoma will be included. Imaging by retroillumination will be realized. In case of bilateral disease, both eyes will be photographed | Device: Retro-illuminator<br>* The device Retro-illuminator will be used to photograph the eyes.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Percentage of pictures without reflection (%) | Evaluation of the device's retroillumination. Pictures without reflection: no reflection or a minimal reflection without loss of information. | Year: 1 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Percentage of pictures clean on the pathological area (%) | Evaluation of the device's retroillumination. Pictures clean : absence of blur, or minimal blurred that does not result in loss of information.. | Year: 1 | 
| Serious adverse events | Number of serious adverse events | Year: 1 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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pigmentary glaucoma, crystalline pathology, corneal pathology, Retroillumination, Infrared