The Cartilage and Muscle Thickness on Knee Pain in Patients With Rheumatoid Arthritis

Study Overview
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Brief Summary
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The knee pain status of the patients who are followed in the rheumatology special branch of the Physical Medicine and Rehabilitation Outpatient Clinic and who meet the inclusion criteria will be questioned. In patients with or without knee pain, the cartilage thickness measurement of the knee joint will be measured from 3 points by ultrasound. At the same time, Quadriceps and Hamstring muscle thickness measurements of the patients will be made from the midpoints where the muscle thickness is the highest. The physician who performed the ultrasonographic measurements of the knee pain status of the patients does not know.

Official Title
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The Effect of Ultrasonographic Cartilage Thickness and Quadriceps/Hamstring Muscle Thickness on Knee Pain in Patients With Rheumatoid Arthritis

Conditions
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Rheumatoid Arthritis, Knee Pain Chronic, Muscle Loss, Cartilage Degeneration

Intervention / Treatment
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* Diagnostic Test: Ultrasonographic Measurements


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Rheumatoid Arthritis > Diagnosed for 1 year -Female gender -The patient has been in remission or low disease activity for at least 3 months -Be able to ambulatory -No significant deformity in the lower extremity joints Exclusion Criteria: Patient with active arthritis or high disease activity - Significant deformity of the lower extremity joints and inability to ambulate -Pregnant patient - Presence of malignancy - Patient with a severe psychiatric disorder and difficulty in cooperation - Presence of cardiovascular and pulmonary comorbidities that will prevent exercise -Male gender

Ages Eligible for Study
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Minimum Age: 30 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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Female

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Rheumatoid Arthritis Patients with Knee Pain<br>In patients with knee pain, the cartilage thickness measurement of the knee joint will be measured from 3 points by ultrasound. At the same time, Quadriceps and Hamstring muscle thickness measurements of the patients will be made from the midpoints where the muscle thickness is the highest. | Diagnostic Test: Ultrasonographic Measurements<br>* In patients with or without knee pain, the cartilage thickness measurement of the knee joint will be measured from 3 points by ultrasound. At the same time, Quadriceps and Hamstring muscle thickness measurements of the patients will be made from the midpoints where the muscle thickness is the highest.<br>|
| Rheumatoid Arthritis Patients without Knee Pain<br>In patients without knee pain, the cartilage thickness measurement of the knee joint will be measured from 3 points by ultrasound. At the same time, Quadriceps and Hamstring muscle thickness measurements of the patients will be made from the midpoints where the muscle thickness is the highest. | Diagnostic Test: Ultrasonographic Measurements<br>* In patients with or without knee pain, the cartilage thickness measurement of the knee joint will be measured from 3 points by ultrasound. At the same time, Quadriceps and Hamstring muscle thickness measurements of the patients will be made from the midpoints where the muscle thickness is the highest.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Ultrasonographic Cartilage Thickness Measurement | Tibial cartilage thickness will be visualized by ultrasound with the knee held in 30 degrees of flexion, and 3 measurements will be taken from the medial, lateral and midline. | through study completion, an average of 1 month | 
| Ultrasonographic Muscle Measurement Thickness Measurement | The quadriceps muscle thickness will be measured by determining the midpoint between the SIAS and the patella while the patient is lying in the supine position. Hamstring muscle thickness will be measured at the intersection of a line drawn at 60% distal between the greater trochanter and the outer femoral condyle, and at the midline of the popliteal fossa, with the patient lying on the prone. These 2 measurements will be proportional to each other. | through study completion, an average of 1 month |