Evaluation of Retinal Microvascular Change That May Develop in Patients After Open Globe İnjury With Optical Coherence Tomography (OCTA)

Study Overview
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Brief Summary
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The aim of this study is to evaluate posterior segment changes in the non-traumatic eye after open globe injury.

Detailed Description
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Globe injuries can be classified as either closed- or open-globe injuries, based on the integrity of the sclera and cornea. Open-globe injury (OGI) is characterized by a full-thickness wound of the ocular wall. As one of the most severe forms of ocular trauma, open-globe injury (OGI) causes significant vision loss. Timely and meticulous repair of these injuries can improve patient outcomes. OGI by rupture often occurs at the weakest point of the eye wall, which may or may not be at the actual injury site. The rupture site is most commonly found in the sclera concentric to the limbus, just posterior to the insertion of the extraocular muscles. After trauma, changes may occur in the non-trauma eye. Retinal and choroidal circulation may change as a result of adaptation mechanisms. In this study, we evaluated the vascular densities of the control group and post-traumatic non-trauma eye.

Official Title
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Evaluation of Retinal Microvascular Change That May Develop in Patients After Open Globe İnjury With Optical Coherence Tomography (OCTA)

Conditions
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Eye Injuries

Intervention / Treatment
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* Other: Optical Coherence Tomography Angiography (OCTA) • Biometry • Auto refractometry • Non contact tonometry


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Be over 18 years old Unilateral eye injury Exclusion Criteria: Be under the age of 18 Usage of systemic drugs or topical ocular drops Bilateral eye injury Having systemic disease, having ocular pathology that may decrease visual acuity

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Trauma Group<br>Non-Trauma Eye After Open-Globe Injury | Other: Optical Coherence Tomography Angiography (OCTA) • Biometry • Auto refractometry • Non contact tonometry<br>* Ophthalmologic Examination Measurements of best-corrected visual acuity, refractive error, intraocular pressure, axial length, slit lamp examination of the anterior segment, dilated fundus examination, and anterior segment parameters, optical coherence tomography angiography (OCTA)<br>|
| Control Group<br>Age-, sex-matched healthy volunteers | Other: Optical Coherence Tomography Angiography (OCTA) • Biometry • Auto refractometry • Non contact tonometry<br>* Ophthalmologic Examination Measurements of best-corrected visual acuity, refractive error, intraocular pressure, axial length, slit lamp examination of the anterior segment, dilated fundus examination, and anterior segment parameters, optical coherence tomography angiography (OCTA)<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| OCTA Vascular densities | optical coherence tomography angiography (OCTA) | 32 weeks | 
| Anterior chamber depth | Anterior chamber depth in mm | 32 weeks | 
| Tonometry | İntraocular pressure measurement in mmHg | 32 weeks | 
| Best corrected visual acuity assessment | Snellen and logMAR chart | 32 weeks | 
| Axial length | Axial length in mm | 32 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Eye Injuries, Optical Coherence Tomography Angiography