Comprehensive Geriatric Assessment in the Elderly Subjects (PROMISING)

Study Overview
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Brief Summary
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The primary objective of this observational study is to verify, through a comprehensive geriatric assessment, the health status of a sample of elderly subjects.

Detailed Description
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The primary objective of this observational study is to verify, through a comprehensive geriatric assessment, the health status of a sample of elderly subjects. Short- to medium-term outcomes will also be evaluated through follow-up.

Official Title
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Comprehensive Geriatric Assessment in the Elderly Subjects (PROMISING)

Conditions
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Ageing, Frailty

Intervention / Treatment
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* Other: comprehensive geriatric assessment


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: subjects with 65 years or older Exclusion Criteria: no informed consent

Ages Eligible for Study
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Minimum Age: 65 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| elderly subjects<br>subjects aged 65 years and over | Other: comprehensive geriatric assessment<br>* The clinical, biological and functional characteristics will be collected in elderly subjects attending the hospitals of participating centers.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in health conditions | The prevalence of comorbidities and their risk factors at time of enrolment | Baseline, 3, 6 and 12 months later | 
| Change in prevalence of polypharmacy | Number of participants with polypharmacy. Polypharmacy will be defined as being on five or more medications at one time | Baseline, 3, 6 and 12 months later | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in frailty condition | Clinical Frailty Scale (CFS). The CFS divides patients into 9 classes from very fit (CFS=1) to terminally ill (CFS=9) | Baseline, 3, 6 and 12 months later | 
| Change in functional capacity | Activity of Daily Living (ADL). A summary score ranges from 0 (low function, dependent) to 6 (high function, independent) | Baseline, 3, 6 and 12 months later | 
| Change in functional capacity | Activity of Instrumental of Daily Living (IADL). A summary score ranges from 0 (low function, dependent) to 8 (high function, independent) | Baseline, 3, 6 and 12 months later | 
| Change in physical performance | Physical performance will be ascertained using the Short Physical Performance Battery (SPPB). Summary scores range from 0-12 and higher scores denote higher physical performance | Baseline, 3, 6 and 12 months later | 
| Change of cognitive function score | Mini-mental State Examination (0-30 points), the higher the score, the better the cognitive function | Baseline, 3, 6 and 12 months late | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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comprehensive geriatric assessment, polypharmacy, ageing