Resistive Exercise Versus HIIT on Calcium and Vitamin D

Study Overview
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Brief Summary
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A comparison between resistive exercise and high intensity interval trainig on calcium and vitamin d in premenopausal women.

Detailed Description
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A total of 57% of women were vitamin D deficient with higher vitamin D deficiency found among premenopausal women (64.7%). Concentrations of 25(OH) D, defined as severely deficient (< 12 ng/ml), deficient (12-19 ng/ml), insufficient (20-30 ng/ml) and sufficient (> 30 ng/ml). Both severe vitamin D deficiency and calcium deficiency was significantly more frequent in premenopausal women compared to postmenopausal women. So, it is important to find effective therapeutic approaches to treat vitamin D deficiency among these women

Official Title
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Resistive Exercise Versus High Intensity Interval Training on Calcium and Vitamin D in Premenopausal Women: A Randomized Controlled Trial

Conditions
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Vitamin D Deficiency, Calcium, Premenopause

Intervention / Treatment
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* Other: resistive exercise
* Other: high intensity interval training
* Dietary Supplement: calcium and vitamin D


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Premenopausal women having reduced calcium level (less than 500mg) intake as recorded by 24 hours' dietary recall method and vitamin D deficiency (12-19 ng/ml). Their ages will range from 40 to 45 years. Their BMI will range from 25-30 kg/m2. Don't receive hormonal replacement therapy. Exclusion Criteria: Smoking. History of chronic disease (uncontrolled hypertension, diabetes mellitus) Osteoporosis. severe musculoskeletal disorders cardiovascular disease, thyroid dysfunction

Ages Eligible for Study
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Minimum Age: 40 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: resistive exercises<br>Premenopausal women in group A will perform resistive exercise for upper and lower limbs, three times per week in addition to calcium and vitamin d supplementations. | Other: resistive exercise<br>* They will perform combined upper and lower resistive exercises, 30 min, 3 sessions / week for 12 weeks in addition to calcium and vitamin D supplements.<br>Dietary Supplement: calcium and vitamin D<br>* they will receive calcium and vitamin D supplements only.<br>|
| Experimental: high intensity interval training<br>Premenopausal women in group B will receive high intensity interval training for three times per week in addition to calcium and vitamin D supplementations | Other: high intensity interval training<br>* They will perform HIIT for three sessions/ week for 12 weeks, 30 minutes/ session in addition to calcium and vitamin D supplements.,<br>Dietary Supplement: calcium and vitamin D<br>* they will receive calcium and vitamin D supplements only.<br>|
| Active Comparator: conventional therapy<br>Premenopausal women in group C will receive calcium and vitamin D supplementations only. | Dietary Supplement: calcium and vitamin D<br>* they will receive calcium and vitamin D supplements only.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Vitamin D serum level | a blood sample of each participant will be taken to measure serum vitamin D level before and after the study | three months | 
| serum calcium level | a blood sample will be taken from each participant to measure calcium level of each participant before and after the study. | three months |