linjc16/ctgov huggingface dataset:
ScanNav Anatomy PNB Data Collection Study

Study Overview
=================
Brief Summary
-----------------
Study to gather additional data for AI-driven medical device, ScanNav Anatomy PNB.

Detailed Description
-----------------
Volunteer study to gather additional ultrasound training and/or validation data for Artificial Intelligence (AI)-algorithms used in the medical device ScanNav Anatomy PNB.

Official Title
-----------------
ScanNav Anatomy PNB Data Collection Study

Conditions
-----------------
Data Collection

Intervention / Treatment
-----------------
* Other: N/A - non-interventional study


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Male or female, at least 18 years of age; Able to comprehend and sign the Informed Consent prior to enrolment in the study. Exclusion Criteria: Aged <18 years of age; Unwilling or unable to provide informed consent.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Volunteer Participants<br>Volunteer participants being scanned by a qualified clinician using various ultrasound machines. | Other: N/A - non-interventional study<br>* N/A - non-interventional study. Data collection only.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Training and/or validation data (in the form of recorded ultrasound scans) | Ultrasound scans to be used for training and/or validation of AI models developed in-house to assist ultrasound-guided regional anaesthesia. | 6 months |
Psychomotor Performance of Preterm Infants

Study Overview
=================
Brief Summary
-----------------
The first part involved 120 children in grades II and III of elementary schools. From this group, children were qualified for the second part of the study - 35 randomly selected children born on time (BoT) and 35 children born before 35 weeks of pregnancy (PB). EUROFIT tests, Vienna Tests and postural stability tests were carried out in both groups.

Official Title
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Psychomotor Performance of Preterm Infants Born Between 24 and 35 Weeks of Gestation

Conditions
-----------------
Psychomotor Development Impaired

Participation Criteria
=================
Eligibility Criteria
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Inclusion Criteria: preterm born (PB): born before 35 weeks of gestation both groups: aged 7-9 y during the research project Exclusion Criteria: musculoskeletal injuries neurological disorders or other CNS damage

Ages Eligible for Study
-----------------
Minimum Age: 7 Years
Maximum Age: 9 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Eurofit test | Motor abilities | 20 minutes | 
| Biodex Balance System SD | Static and dynamic postural stability | 15 minutes | 
| Vienna Test | Speed reactions | 15 min minutes | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Preterm Birth, Preterm Infant, Motor abilities, Eurofit, Vienna test, Postural stability
The Management of Complicated Colo-rectal Cancer in Older Patients in the Emergency Setting: the CO-OLDER Study

Study Overview
=================
Brief Summary
-----------------
This is a multicenter observational study aimed to investigate the management of older patients aged 75 years old and over admitted to the emergency department with complicated colorectal cancer. The final endpoint is to report morbidity and mortality in this group of frail individuals according to the shift of incidence of colorectal cancer in geriatric patients, over 2 periods: before the COVID pandemic outbreak (11th March 2020) and after the 11th March, during the ongoing pandemic.

Official Title
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The Management of Complicated Colo-rectal Cancer in Older Patients in the Emergency Setting: the CO-OLDER Study

Conditions
-----------------
Advanced Colorectal Cancer in Elderly Patient

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients aged 75 years old and over; Admission to the emergency department with acute abdominal pain; Diagnosis of obstructed and/or perforated colorectal cancer. Exclusion Criteria: Patients aged< 75 years old; Patients aged >=75 years old admitted with acute abdomen, not due to complicated colorectal cancer.

Ages Eligible for Study
-----------------
Minimum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| mortality and morbidity correlated with the management of older (=>75 years old) patients admitted to emergency department with a complicated colorectal cancer |  | through study completion, an average of 1 year | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
elderly; oldest; colorectal cancer; perforation; bleeding; obstruction; emergency; surgery; laparotomy; laparoscopy; futility; frailty
Prediction of Propofol Effect Compartment Concentrations

Study Overview
=================
Brief Summary
-----------------
The goal of this observational study is to learn about the prediction of the effect of Propofol by means of EEGs. The main questions it aims to answer are: Develop models that can reliably predict the effect of Propofol Select the most well suited model for clinical practice Compare this model to already existing models (e.g. Schnider-model) Participants will asked to allow us to collect and use the EEG data recorded during the operations.

Official Title
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Prediction of Propofol Effect Compartment Concentrations

Conditions
-----------------
Analysis of Anaesthesia Depth

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age of 18 or older at the time of the signature of the informed consent Signed informed consents Planned TIVA with Propofol Exclusion Criteria: Use of extracorporal circulation (e.g., HLM, ECMO) Admission to an ICU/IMCU before the operation or planned admission to an ICU/IMCU after the operation Administration of Propofol seven days prior to the planned operation Missing informed consent All contraindications against TIVA (e.g., allergy against Propofol or soy) All operations where BIS monitoring cannot be used (e.g., skin lesions on the front) Patients for which the administration of Propofol could be potentially harmfull (e.g., severe heart failure with the risk of drop of blood pressure) Neurosurgical operations

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bilateral BIS values (derived from EEG) | Comparison of Predicted and Measured EEG values (recorded every five seconds) | During procedure (From the beginning of general anaesthesia (induction of anaesthesia) until the patient has woken up (end of anaesthesia)). | 
| Propofol cumulative dose | Cumulative dose of Propofol (recorded every second) | During procedure (From the beginning of general anaesthesia (induction of anaesthesia) until the patient has woken up (end of anaesthesia)). |
A Non-interventional Study With Advanced Lung Squamous Cell Carcinoma

Study Overview
=================
Brief Summary
-----------------
This is a descriptive observational study, in which data are collected in an epidemiological fashion and prospective. This study does not intend to intervene the current medical practice of the recruited patients.

Official Title
-----------------
A Non-interventional Study and Its Clinical Relevance With Advanced Lung Squamous Cell Carcinoma

Conditions
-----------------
Advanced Lung Squamous Cell Carcinoma

Intervention / Treatment
-----------------
* Other: No treatment is included in this study


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients must be ≥18 years. Provision of fully informed consent prior to any study specific procedures. Advanced or metastatic lung squamous cell carcinoma confirmed by histology or cytology. According to the RECIST 1.1 standard, the patient must have at least one measurable lesion. Exclusion Criteria: None

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: No treatment is included in this study|No drug intervention or tissue sampling will be included in this study.|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| progression-free survival | From registration onto that step until death, or censored at the date of last contact. | 2 years | 
| Overall survival | From registration onto that step until death, or censored at the date of last contact. | 2 years |
Eating Disorders Among Adolescents

Study Overview
=================
Brief Summary
-----------------
The aim of the present study is to evaluate the prevalence of eating disorder among adolescents. Also, to evaluate psychiatric comorbidity, sleep problems, alexithymia and emotion dysregulation associated with patients had eating disorders. In addition, to identify possible risk factors associated with eating disorder among adolescents.

Official Title
-----------------
Assessment of Prevalence of Eating Disorder Among Adolescents and it's Risk Factors

Conditions
-----------------
Eating Disorders

Intervention / Treatment
-----------------
* Behavioral: eating disorders


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age between 10 to 18 years old. Males and females are included. Exclusion Criteria: - participants were previously diagnosed with any psychiatric disorder.

Ages Eligible for Study
-----------------
Minimum Age: 10 Years
Maximum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: eating disorders|Assessment of eating disorders among adolescents|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| eating disorders among adolescents | Assessment of prevalence of eating disorder among adolescents and it's risk factors | baseline |
Eighteen-month Orthodontic Bracket Survival Rate With the Conventional Bonding Technique Versus RMGIC and V-prep

Study Overview
=================
Brief Summary
-----------------
The aim of this study was to evaluate over eighteen months the clinical bonding failure and survival rates of the conventional bonding technique using the Transbond XT (3M Unitek, Monrovia, California, USA) and the RMGIC Fuji Ortho LC (GC Corporation, Tokyo, Japan) prepared with the V-prep. Therefore, one operator using the straight-wire technique bonded two hundred metallic brackets to upper and lower premolars of twenty-five patients requiring an orthodontic treatment. The randomized trial was a single-blind design in a split-mouth comparison. Each patient was randomly allocated one of the two bonding systems for each premolar on each side of the mouth. The bonding and rebonding techniques were standardized throughout the trial and bond failure was recorded each month for a period of eighteen months.

Official Title
-----------------
Eighteen-month Orthodontic Bracket Survival Rate With the Conventional Bonding Technique Versus RMGIC and V-prep: A Split-mouth RCT

Conditions
-----------------
Dental Malocclusion

Intervention / Treatment
-----------------
* Combination Product: v-prep combined with RMGIC for bracket bonding
* Combination Product: Conventional bracket bonding technique


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: require full orthodontic treatment of both arches mild or average overbite and crowding no restorations on the buccal surface of the premolars Exclusion Criteria: Patients with required extractions in the treatment plan or with poor oral hygiene

Ages Eligible for Study
-----------------
Minimum Age: 12 Years
Maximum Age: 15 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Conventional bracket bonding technique<br> | Combination Product: Conventional bracket bonding technique<br>* prepare the tooth with acid-etch, then bond a bracket using resin composite<br>|
| Experimental: V-prep combined with RMGIC for bracket bonding<br> | Combination Product: v-prep combined with RMGIC for bracket bonding<br>* prepare the tooth surface with the V-prep, then bond a bracket with the RMGIC<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bracket bonding survival rate | reports of bracket debonding using one of the two bonding techniques | 18 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
resin-modified glass ionomer, surface preparation, orthodontic bracket
Nipple Neurotization

Study Overview
=================
Brief Summary
-----------------
A retrospective chart review will be conducted to identify patients receiving breast reconstruction and simultaneous breast neurotization. Their reconstructed breasts will be included as study group. Patients receiving breast reconstruction without neurotization will be included as negative control group. Their contralateral normal breasts in the study and the negative control group will be included as positive control. Patients' demographic data, their breast cancer treatment parameters, such as the staging, previous radiotherapy history, postmastectomy radiotherapy, neoadjuvant and adjuvant chemotherapy will be included. The reconstruction results will be evaluated as well. Statistics Data will be analyzed using graphing and statistical analysis software. Independent t test will be applied to calculate continuous variables in demographic values, while Chi-square will be applied to calculate categorical variables such as postoperative complications. A probability of less than 0.05 will be considered significant. Potential risks: No Confidentiality: All the patient identifiable information, which includes name, chart number and birthday, involved in the study will be strictly confidential.

Official Title
-----------------
Breast and Nipple Neurotization Via Elongation of the Lateral Cutaneous Branches Using Intercostal Branches

Conditions
-----------------
Breast Reconstruction

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients who received breast reconstruction and neurotization from July 2019 to August 2022 from a single breast reconstruction surgeon. patients who received breast reconstruction without neurotization were included as the non-neurotized group. Exclusion Criteria: patients unable to complete the follow-up were excluded from the study
Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Neurotized<br> | |
| Non-neurotized<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes of monofilament force at 6, 12, 18, 24, and 30 months post-operatively |  | post-operative 6, 12, 18, 24, and 30 months |
Clinical Assessment of a Daily Disposable Soft Silicone Hydrogel Contact Lens

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to assess the clinical performance of DAILIES TOTAL1® spherical soft contact lenses over approximately 1 week of daily wear.

Detailed Description
-----------------
Subjects will be expected to attend 2 visits (Visit 1 Screen/Baseline/ Dispense; and Visit 2 Week 1 Follow-up/ Exit). The total duration of a subject's participation in the study as well as exposure to the contact lenses will be approximately 1 week (6-8 days of contact lens wear).

Official Title
-----------------
Clinical Assessment of a Daily Disposable Soft Silicone Hydrogel Contact Lens

Conditions
-----------------
Refractive Errors

Intervention / Treatment
-----------------
* Device: Delefilcon A contact lenses


Participation Criteria
=================
Eligibility Criteria
-----------------
Key Inclusion Criteria: Current wearer of commercial spherical soft contact lenses in both eyes with at least 3 months of wearing experience, with a minimum wearing time of 5 days per week and 10 hours per day; Manifest cylinder less than or equal to 0.75 diopter (D) in each eye; Best corrected distance visual acuity better than or equal to 20/25 (Snellen) in each eye. Key Exclusion Criteria: Current or prior habitual DAILIES TOTAL1 soft contact lens wear in the past 3 months prior to consent; Monovision contact lens wear; Wearing habitual contact lenses in an extended wear modality (routinely sleeping in lenses for at least 1 night per week) over the last 3 months prior to enrollment.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: DAILIES TOTAL1<br>Delefilcon A contact lenses worn in both eyes for the typical number of hours the subject wears his/her habitual contact lenses. The lenses will be worn in a daily disposable manner. | Device: Delefilcon A contact lenses<br>* Daily disposable, silicone hydrogel spherical contact lenses<br>* Other names: DAILIES TOTAL1;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Distance VA with study lenses at Week 1 | Visual acuity (VA) will be measured with study lenses on eye using letter charts. VA will be recorded in Snellen where 20/20 represents normal distance eyesight. | Week 1 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Contact Lenses
Paraneoplastic Syndrome in Hepatocellular Carcinoma Patients

Study Overview
=================
Brief Summary
-----------------
Hepatocellular carcinoma (HCC) is the sixth most common cancer in the world with rising incidence. Globally, there has been substantial variation in prevalence of risk factors for HCC over years, like control of viral hepatitis in developing countries but growing epidemic of fatty liver disease in developed world. Changing epidemiology of HCC is related to trends in these risk factors, Paraneoplastic syndromes (PNS) are defined as systemic, metabolic, or other distant consequences of malignancy resulting, either directly or indirectly, from production by the neoplasm of substances that gain access to the blood stream, thereby exerting their effects on distant organs or tissues There is four major HCC-associated paraneoplastic syndromes among Cirrhotic patients,i.e.hypercholesterolemia,hypoglycemia,hypercalcemia,and erythrocytosis .

Official Title
-----------------
Paraneoplastic Syndrome in Hepatocellular Carcinoma Patients

Conditions
-----------------
Hepatocellular Carcinoma Patients

Intervention / Treatment
-----------------
* Diagnostic Test: Triphasic C.T abdomen and pelvis


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: - Cirrhotic Patients with HCC. HCC will be diagnosed based on Alpha -feto protein (AFP) and dynamic imaging. Exclusion Criteria: - Patient known to have primary parathyroid disease, patients with bone metastasis or excessive use of antacids. Patients with secondary polycythemia (as chronic hypoxia) and patients with polycythemia rubra vera. Patients with acute infections or GIT bleeding. Patients with preexisting dyslipidemia. Patients with significant cholestasis.

Ages Eligible for Study
-----------------
Minimum Age: 40 Years
Maximum Age: 100 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: Triphasic C.T abdomen and pelvis|for cirrhotic patients to ensure hepatocellular carcinoma|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the prevalence of Paraneoplastic Syndrome in cirrhotic Patients with HCC. | To investigate the prevalence of PNS (hypoglycemia, hypercholesterolemia, hypercalcemia, erythrocytosis, and thrombocytosis) and clinical characteristics in cirrhotic Patients with HCC. | 12 months |
Coronary Collaterals and Post-reperfusion Intramyocardial Hemorrhage

Study Overview
=================
Brief Summary
-----------------
This study examines the relationship between angiographic coronary collaterals (Rentrop grades) and post-reperfusion microvascular injury. This study aims to assess the impact of coronary collateral circulation on intramyocardial hemorrhage incidence and extent.

Official Title
-----------------
Impact of Coronary Collaterals on Intramyocardial Hemorrhage in AMI Patients

Conditions
-----------------
Acute Myocardial Infarction

Participation Criteria
=================
Eligibility Criteria
-----------------
Age ≥ 18 years Index STEMI Coronary angiogram with PCI Cardiac MRI

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of Intramyocardial hemorrhage (IMH) | Collaterals grades (0-III) will be correlated with incidence rate of IMH | Day 3 | 
| Volume of Intramyocardial hemorrhage (IMH) | Collaterals grades (0-III) will be correlated with IMH volume | Day 3 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Coronary Angiography, Intramyocardial Hemorrhage, Cardiac Magnetic Resonance