Comparison Of The Immediate Effects Of Manipulation On The Autonomic Nervous System

Study Overview
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Brief Summary
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High velocity low amplitude thrust applied at the vertebral level during spinal manipulation is thought to slide the vertebrae over each other and alter segmental biomechanics.

Detailed Description
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Evidence suggests that spinal HVLA techniques may produce acute changes in skin sympathetic nerve activity. There are studies reporting that thoracic HVLA manipulation causes a statistically significant increase in cardiac vagal activity in the immediate post-intervention period compared to sham administration.

Official Title
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Comparison Of The Immediate Effects Of Manipulation On The Autonomic Nervous System

Conditions
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Vagus Nerve Autonomic Disorder

Intervention / Treatment
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* Other: Supine practice group
* Other: Prone application group


Participation Criteria
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Eligibility Criteria
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Inclusion criteria: People who volunteered to work and signed the consent form Not having any of the application contraindications or exclusion criteria. Being between the ages of 18-45 Exclusion criteria: Presence of tumor, infection, trauma, inflammation Neurological problems (Acute myelopathy, spinal cord compression, cauda equina syndrome, nerve root compression) Vascular disorders (Vertebrobasilar insufficiency or cervical artery abnormalities, aortic aneurysm, angina pectoris, acute abdominal pain with preservation)

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Supine practice group<br>The participant was asked to cross his arms in front of his body while lying on his back. | Other: Supine practice group<br>* The practitioner's arm was placed in the mid-thoracic region from the opposite side of the individual's torso in the form of a half fist. In this position, the SPs coincide with the space in the middle of the half fist, while the TPs coincide with the fingertips and the thenar region. With the practitioner's other hand supporting the patient's elbows, a high-speed-low-amplitude thrust is applied from front to back.<br>|
| Experimental: Prone application group<br>The participant positions their hands freely from the side of the treatment table in the prone position. | Other: Prone application group<br>* the practitioner positions the hypothenar part of his hands above the TPs in the mid-thoracic segment. From this point, a high-velocity-low-amplitude thrust is applied from the back to the front.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Autonomic nervous system device | The Polar H10 device is a heart rate sensor that comes with a wearable chest strap and is the gold standard of high sensitivity and accuracy. It can be connected to multiple training devices via Bluetooth and ANT+. The device comes with a soft, adjustable sensor that touches the chest to capture the heart rate in real time. In the study, the autonomic nervous system will be evaluated with the Polar H10 device. By connecting the device to a smart phone via bluetooth, the data will be recorded and the software supported by the device will be used for the analysis of the data. | one day | 
| Finger Oximeter | Finger oximeter (finger pulse oximeter) measures heart rate per minute and oxygen level in blood easily and quickly. This device, which is placed on the fingertip, measures the oxygen saturation by sensing the color tone changes in the blood depending on the oxygen with infrared rays. Oxygen saturation refers to the oxygen saturation in the blood. Typical oxygen saturation levels in a healthy person range from 95-100%. In people with lung problems, these values may be slightly lower. | one day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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manipulation