The Relationship Between Personality Traits and Perioperative Anesthetic Drug Consumption

Study Overview
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Brief Summary
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In this study, we aimed to examine the association between personality traits and amount of anesthetic drug consumption,of the patients who will receive sedoanalgesia for the oocyte retrieval procedure. As well as determining the anxiety scores in the preoperative period, the time to reach the desired sedation level, hemodynamic parameters in the perioperative period, peripheral oxygen saturation, EtCO2 value, postoperative pain, postanesthetic recovery, analgesic drug need, unconscious movement, and patient satisfaction.

Detailed Description
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Different personality traits, anxiety disorders, depression, and somatoform disorders are frequently encountered in women with infertility problems. Although there are many studies evaluating the relationship of anxiety with variables such as hemodynamic parameters, need for anesthetic medication, recovery times, postoperative pain and analgesic requirements, the relationship between personality traits and these variables has not been investigated. In our study, considering that the anesthesia needs of these patients with a stressful negative factor such as infertility may be at different levels, preoperative evaluation of the patients with a personality questionnaire will provide better perioperative management, a better quality recovery and possibly a higher quality oocyte aspiration. In this study, it was aimed to investigate the amount of anesthetic agent consumption, recovery times, postoperative pain scores, analgesic requirements, involuntary movement, time to reach sufficient sedation depth, and patient satisfaction of patients thought to have sedation. All patients will fill out Personality Belief Scale-Short Form (PBQ-S1) and Beck Anxiety Scale one day before the procedure and they will be registered.

Official Title
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The Relationship Between Personality Traits and Perioperative Anesthetic Drug Consumption

Conditions
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Anesthesia, Infertility

Intervention / Treatment
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* Other: PBQ-S1


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 18- 50 year-old elective patients who signed the informed consent form from ASA I-II patients scheduled for oocyte retrieval. Patients with sufficient education and mental capacity to complete in assessment scales and questionnaires. Patients without neurological disorders, psychological illnesses, or drug or alcohol abuse Patients without stimulant drug and alcohol consumption Absence of significant cardiovascular, respiratory, kidney or liver disease. Exclusion Criteria: Psychiatric or neurological disorder Psychiatric drug use or alcohol consumption Pregnancy Presence of severe cardiac, hepatic or cerebrovascular disease History of allergy to local anesthetics or systemic opioids History of chronic pain Patients who are unable to evaluate scales and questionnaires

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Group PT-PADC<br>patients who will receive sedoanalgesia for the oocyte retrieval procedure. | Other: PBQ-S1<br>* All patients will fill out Personality Belief Scale-Short Form (PBQ-S1) and Beck Anxiety Scale one day before the procedure and they will be registered.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Propofol consumption | mg, from the beginning to the end of the transvaginal oocyte retrieval procedure | from the beginning to the end of the transvaginal oocyte retrieval procedure) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Time until the Ramsey Sedation Score of 4 is reached | The period elapsed after the patient is transported to the operating table and the sedation protocol begins. | -The period of time starting with the propofol injection until the Ramsey Sedation Score of 4 | 
| Amount of propofol (mg) used until the required sedation depth is reached | The amount of iv propofol administered until the Ramsey Sedation Score of 4 is obtained | The period of time starting with the propofol injection until the Ramsey Sedation Score of 4 | 
| Systolic, diastolic and, mean Blood pressure (mm/Hg) | It will be monitored and documented every 5 minutes during the procedure. | every 5 minutes during the procedure | 
| Heart rate (beats/min) | It will be monitored and documented every 5 minutes during the procedure. | every 5 minutes during the procedure. | 
| Peripheral oxygen saturation (%) | (%): It will be monitored and documented every 5 minutes during the procedure. | every 5 minutes during the procedure | 
| Number of Involuntary movement during the procedure | The presence of involuntary movement will be documented during the procedure. | during the procedure. | 
| Postoperative pain (visual analog scale) | Pain status will be evaluated based on visual analog scale (VAS) at rest and after movement.every 30-minute intervals for one hour in the recovery room. Each VAS is scores 0-10 (0=no pain, 10=unbearable pain) | After the procedure,every 30 minutes up to 1 hour | 
| Analgesic consumption | The analgesic agents administered to the patients throughout the postoperative period will be documented. | postoperatively up to 2 hours | 
| Postoperative recovery time | The time until the Modified Aldrete Score reaches 9 points will be determined. | postoperatively up to 2 hours | 
| The incidences of post-operative nausea and vomiting (PONV) | the presence of nausea and vomiting will be recorded for 24 hours after procedure | the time from the end of the procedure until discharge | 
| Undesirable events and interventions | Bradycardia, hypotension, airway obstruction, hypoxia will be documented throughout the perioperative phase with the intervention. | time between start of procedure and discharge | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Personality traits, Anesthetic Drug Consumption, Anxiety, Acute pain