Optimising Screening of Intermediate to High-risk Asymptomatic Sportsmen With Exercise Electrocardiogram

Study Overview
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Brief Summary
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The importance of exercise electrocardiogram (ECG) is still controversial in the prevention of cardiac events among sportsmen. The aim of this study was to assess the relevance of exercise electrocardiogram (ECG) as a significant prognostic marker for cardiovascular events when any cardiovascular disease (CVD) risk factors are present.

Detailed Description
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The SEEPRED (Sport, Exercise ECG, prediction) prospective cohort study included leisure time sportsmen over 35 years old who performed exercise electrocardiogram (ECG) screening in the Sports Medicine Unit of the University Hospital of Saint-Etienne from September 2011 to April 2016. Personal, familial history and physical examination were systematically performed before maximal exercise electrocardiogram (ECG). Cardiovascular events and changes in physical activity were searched after exercise electrocardiogram (ECG).

Official Title
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Optimising Screening of Intermediate to High-risk Asymptomatic Sportsmen With Exercise Electrocardiogram. The SEEPRED Study.

Conditions
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Electrocardiography

Intervention / Treatment
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* Diagnostic Test: Screening stress test on a bicycle ergometer (usual practise)


Participation Criteria
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Eligibility Criteria
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Inclusion criteria: Patients referred as asymptomatic by their general practitioner for an exercise electrocardiogram (ECG) screening test carried out as a standard procedure for resuming physical activity Patients referred as a systematic pre-participation screening to be declared an athlete. Exclusion criteria: Patients with coronary artery disease (CAD) and Patients with uninterpretable ST segment due to bundle branch block

Ages Eligible for Study
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Minimum Age: 35 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Sportsmen<br>Sportsmen (at least 1 hour of physical activity per week) over 35 years of age, referred by their doctor for a screening stress test on a bicycle ergometer in the sports medicine unit from September 2011 to August 2014 | Diagnostic Test: Screening stress test on a bicycle ergometer (usual practise)<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Silent Myocardial ischemia (SMI) | Determine the frequency of exercise-induced silent myocardial ischemia (SMI). | Day 1 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Gender record | Gender will be recording during medical consultation in order to predict positive exercise ECG | Day 1 | 
| Age record | Age will be recording during medical consultation in order to predict positive exercise ECG | Day 1 | 
| Physical activity levels record | Physical activity levels will be recording during medical consultation in order to predict positive exercise ECG | Day 1 | 
| Treatment record | Treatment will be recording during medical consultation in order to predict positive exercise ECG | Day 1 | 
| Cardiovascular disease (CVD) risk factors record | Cardiovascular disease (CVD) risk factors will be recording during medical consultation in order to predict positive exercise ECG | Day 1 | 
| Body mass index record | Body mass index will be recording during medical consultation in order to predict positive exercise ECG | Day 1 | 
| Score>5% record | SCORE >5% will be recording during medical consultation in order to predict positive exercise ECG | Day 1 | 
| Maximal heart record | Maximal heart rate will be recording during medical consultation in order to predict positive exercise ECG | Day 1 | 
| Maximal aerobic power record | Maximal aerobic power will be recording during medical consultation in order to predict positive exercise ECG | Day 1 | 
| Maximal blood lactate level record | Maximal blood lactate level will be collected in order to predict positive exercise ECG | Day 1 | 
| Suspected SMI | Exercise ECG screening test | Day 1 | 
| Confirmed SMI | Exercise ECG screening test | Day 1 | 
| Cardiovascular events | Exercise ECG screening test | Day 1 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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prediction, sport