Prospective Registry Study of Endovascular Treatment for Acute Ischemic Stroke Patients

Study Overview
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Brief Summary
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To investigate the real situation of assessment, diagnosis and treatment of acute ischemic stroke patients with endovascular therapy.

Detailed Description
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Prospective Registry Study of Endovascular Treatment for Acute Ischemic Stroke Patients is an academic,independent, pragmatic , prospective, multicenter, observational registry study. The acute ischemic stroke patients undergone endovascular therapy will be enrolled in stroke centers. Baseline information and clinical follow-up information at 90 days of stroke onset are collected. Data collected include demographics, comorbidities, pathogenesis, blood pressures, stroke severity on admission, time intervals, reperfusion condition, and functional outcome, et al. The study aims to investigate the real situation of assessment, diagnosis and treatment of acute ischemic stroke patients with endovascular therapy.

Official Title
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Prospective Registry Study of Endovascular Treatment for Acute Ischemic Stroke Patients in China

Conditions
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Endovascular Treatment

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Acute ischemic stroke; Brain imaging confirmed intracranial large vessel occlusion: intracranial internal carotid artery (ICA), middle cerebral artery (MCA M1/M2), anterior cerebral artery (ACA A1/A2), basilar artery (BA), vertebral artery (VA V4), and posterior cerebral artery (PCA P1); Initiation of any type of endovascular treatment, including mechanical thrombectomy, aspiration, angioplasty, and stenting; Informed Consent as documented by signature or fulfilling the criteria for emergency consent/ deferral consent Exclusion Criteria: Acute intracranial haemorrhage No evidence of large vessel occlusion on digital subtraction angiography. Patient bedridden or presenting from a nursing home Foreseeable difficulties in follow-up due to geographic reasons (e.g. patients living abroad) -

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The modified Rankin Scale score at 90 days | The range of the modified Rankin Scale is from 0 to 6. A higher score indicates a worse outcome. 0-No symptoms; 1-No significant disability; 2-Slight disability; 3-Moderate disability; 4-Moderately severe disability; 5-Severe disability; 6-Dead. | 90 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Successful reperfusion rate |  | 90 days | 
| symptomatic intracranial hemorrhage or death within 90 days after stroke onset. |  | 90 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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acute Ischemic Stroke, Endovascular Treatment