The Quality of Life in Individuals With Parkinson's Disease

Study Overview
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Brief Summary
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This study aimed to examine the relationship of quality of life with tremor severity and upper limb functionality in individuals with Parkinson's Disease. The differences between Parkinson's Disease Quality of Life Questionnaire, Nine-Hole Peg Test, grip and pinch strength values in the individuals with and without tremor in the study were investigated.

Detailed Description
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Evaluating the relationship between Quality of Life and tremor is needed to determine the best physiotherapy and rehabilitation approaches for individuals with Parkinson's Disease. This study aimed to examine the relationship of quality of life with tremor severity and upper limb functionality in individuals with Parkinson's Disease. Fifty-two individuals with Parkinson's Disease participated in the study. Quality of Life, tremor amplitude, upper limb functionality, grip and pinch strength were evaluated. The relationship of quality of life with tremor severity and upper limb functionality was examined in individuals with Parkinson's Disease. The results of individuals with and without tremor were compared.

Official Title
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A Cross-sectional Study - The Quality of Life in Individuals With Parkinson's Disease: Is it Related to Functionality and Tremor Severity?

Conditions
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Parkinson Disease, Tremor, Functionality

Intervention / Treatment
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* Other: Quality of life
* Other: Upper limb functionality
* Other: Grip and pinch strength
* Other: Tremor amplitude
* Other: Depression and anxiety levels
* Other: Clinical manifestations


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Definite diagnosis of idiopathic Parkinson Disease Age between 40 and 80 years Being literate Having a grade between 1-4 from the Modified Hoehn and Yahr Scale Having a score lower than 11 in Hospital Anxiety and Depression Scale Exclusion Criteria: Who were with any other neurologic or orthopedic or rheumatologic disease affecting the upper extremity Using antidepressants Having vision loss Deep brain stimulation

Ages Eligible for Study
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Minimum Age: 40 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Quality of life|Parkinson's Disease Quality of Life Questionnaire (PDQ-39)|
|Other: Upper limb functionality|Nine-Hole Peg Test|
|Other: Grip and pinch strength|Dynamometer|
|Other: Tremor amplitude|Electromyography|
|Other: Depression and anxiety levels|Hospital Anxiety and Depression Scale|
|Other: Clinical manifestations|The Movement Disorder Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Movement Disorder Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale | The Movement Disorder Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale. Used for the evaluation of clinical manifestations of Parkinson's disease. The scale consists of 4 subscales: the first part is Non-Motor Aspects of Experiences of Daily Living (13), the second part is Motor Aspects of Experiences of Daily Living (13), the third part is Motor Examination (33), and the fourth part is Motor Complications (6). The total number of items in the scale is 65. The minimum score is 0. The maximum MDS-UPDRS score is higher, given the additional items and scores for each body area, with a maximum score of 272. Higher scores indicate greater impact of Parkinson Disease symptoms. | 1 year | 
| Hospital Anxiety and Depression Scale | The Hospital Anxiety and Depression Scale aims to measure symptoms of anxiety and depression and consists of 14 items, seven items for the anxiety subscale (Hospital Anxiety and Depression Scale Anxiety) and seven for the depression subscale (Hospital Anxiety and Depression Scale Depression). Each item is scored on a response-scale with four alternatives ranging between 0 and 3. After adjusting for six items that are reversed scored, all responses are summed to obtain the two subscales. Both depression and anxiety subheadings are scored between 0 and 21. Higher scores indicate greater levels of anxiety or depression. Cut-off scores are 8-10 for doubtful cases and ≥11 for definite cases. | 1 year | 
| Parkinson's Disease Quality of Life Questionnaire (PDQ-39) | Used to assess the quality of life of Parkinson's patients | 1 year | 
| Electromyography | Used to assess the tremor amplitude of Parkinson's patients | 1 year | 
| Nine-Hole Peg Test | Used to assess the upper limb functionality of Parkinson's patients | 1 year | 
| Dynamometer | Used to assess the grip and pinch strength of Parkinson's patients | 1 year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Quality of Life, Upper Limb Functionality, Tremor, Electromyography, Parkinson's Disease