Evaluation of Renal Perfusion With NIRS in Laparoscopic Surgery

Study Overview
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Brief Summary
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The investigators aimed to show the renal damage caused by increased intra-abdominal pressure in laparoscopic surgeries and to investigate whether its reflection on NIRS would be clinically effective.The main question it aims to answer are: Does pneumoperitoneum cause renal damage? NRS monitoring will be performed in patients undergoing laparoscopic surgery. Preoperative and postoperative blood tests will be performed at certain hours. N-GAL, urea and creatinine values will be recorded.

Detailed Description
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Renal NIRS monitoring will be performed in patients undergoing laparoscopic cholecystectomy surgery. Age, gender, BMI, ASA scores, hemogblin/hematocrit values, intraoperative hemodynamic parameters, NIRS values, N-GAL (preoperative, 2nd hour and 24th hour), urea/creatinine (preoperative, postoperative 24th hour) values of the patients will be recorded. . Before the general anesthesia is performed, the renal tissues of the patients will be visualized by ultrasound, the skin-renal cortex distances will be measured, and suitable patients will be included in the study. Basal rSO2 values will be recorded by placing NIRS probes under the 10-11. intercostal space in the bilateral posterior lateral flank region.

Official Title
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Evaluation of Renal Perfusion With NIRS in Adult Patients Undergoing Laparoscopic Cholecystectomy.

Conditions
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Pneumoperitoneum, Renal Injury

Intervention / Treatment
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* Device: NIRS


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients who undergoing elective laparoscopic cholecystectomi surgery lasting longer than 60 minutes BMI:18-25 skin-renal cortex distance measured less than 4 cm on ultrasound ASA I-III Exclusion Criteria: patient who did not give consent patient who had renal operation before, infection, abscess, catheter in the perirenal region hemodynamically unstable patients, patients with renal pathology and abnormal kidney function tests, emergency cases

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients undergoing laparoscopic cholecystectomy.<br>Basal rSO2 values will be recorded by placing NIRS probes under the 10-11th intercostal space in the bilateral posterior lateral flank region. Age, gender, BMI, ASA scores, Hb/Htc values, intraoperative hemodynamic parameters, NIRS values, N-GAL (preoperative, 2nd hour and 24th hour), urea/creatinine (preoperative, postoperative 24th hour) values of the patients will be recorded. . | Device: NIRS<br>* Renal perfusion will be evaluated with NIRS<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluation of renal damage caused by pneumoperitoneum with N-GAL by blood test | Taking a blood test to evaluation N-GAL | During laparoscopic cholecystectomy operation and within 24 hours postoperative | 
| Evaluation of renal damage caused by pneumoperitoneum with urea/creatinin by blood test | Taking a blood test to evaluation urea/creatinine values | During laparoscopic cholecystectomy operation and within 24 hours postoperative | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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laparoscopy, NIRS, N-GAL