Effect of Applying Ujjayi Pranayama on Cortisol in Lupus Patients

Study Overview
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Brief Summary
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stress vulnerability is very common in lupus patients, specifically women, hence the rates of depression , insomnia, easy fatigue perception, anxiety are high in those women. pranayama is a yogic intervention that may treat the above problems

Detailed Description
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lupus patients, specifically 40 women, will divided to group number 1 and group number 2. the women in every group will be 20 women. Group number 1 will receive home-based ujjayi pranayama for six weeks (fifteen minutes in the morning and 15 min in the evening, this training will be online supervised). The group number 2 will not receive Ujjayi pranayama, so it serves as control lupus group

Official Title
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Effect of Applying Ujjayi Pranayama on Cortisol in Lupus Patients

Conditions
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Systemic Lupus Erythematosus

Intervention / Treatment
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* Behavioral: Ujjayi pranayama


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 40 lupus women Exclusion Criteria: lupus co-morbidities illiteracy

Ages Eligible for Study
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Minimum Age: 35 Years
Maximum Age: 55 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: group number 1<br>Group number 1 will receive home-based daily ujjayi pranayama for six weeks (fifteen minutes in the morning and 15 min in the evening, this training will be online supervised). | Behavioral: Ujjayi pranayama<br>* this group will receive home-based daily ujjayi pranayama for six weeks (fifteen minutes in the morning and 15 min in the evening, this training will be online supervised).<br>|
| No Intervention: group number 2<br>The group number 2 will not receive pranayama training, so it serves as control lupus group | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| serum cortisol | it will be taken from women at morning | it will be measured after 6 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| systolic blood pressure | it will be assessed by manual sphygmomanometer | it will be measured after 6 weeks | 
| diastolic blood pressure | it will be assessed by manual sphygmomanometer | it will be measured after 6 weeks | 
| pulse rate | it is number of heart pulsation in minute | it will be measured after 6 weeks | 
| respiratory rate | it is number of respiration in minute | it will be measured after 6 weeks | 
| Pittsburgh Sleep Quality Index | it is a questionnaire assessing sleeping quality | it will be measured after 6 weeks | 
| Fatigue severity scale | it is a questionnaire assessing fatigue severity | it will be measured after 6 weeks | 
| Beck Depression Inventory | it is a questionnaire assessing depression | it will be measured after 6 weeks | 
| State Trait Anxiety Inventory | it is a questionnaire assessing Trait Anxiety | it will be measured after 6 weeks | 
| Stress Vulnerability Scale | it is a questionnaire assessing Stress Vulnerability | it will be measured after 6 weeks |