the Fetal Epicardial Thickness in Obese Pregnant Women (EFT)

Study Overview
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Brief Summary
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the effects of fetal EFT on fetal cardiac function and fetal and maternal outcomes were investigated in obese pregnant women compared with normal-weight pregnant women.

Detailed Description
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All pregnant women underwent a comprehensive fetal anomaly screening. One obstetrician (S.D.) assessed all of the measurements. Every measurement was performed using a convex 2-5 MHz Voluson E8 probe (GE Healthcare, Milwaukee, WI). Fetal biometry, UA, MCA Doppler, cerebroplacental ratio (CPR), modified MPI (mod-MPI), and EFT were assessed in accordance with the International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) guidelines

Official Title
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The Effect of Myocardial Performance Index and Fetal Epicardial Thickness on Perinatal Outcomes in Obese Pregnant Women

Conditions
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Fetus Fetus, Pregnancy Complications

Intervention / Treatment
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* Diagnostic Test: Doppler ultrasonography


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Obese pregnant women normal-weight pregnant women 24-40 gestational week Exclusion Criteria: Twin pregnancies, structural and chromosomal abnormalities, fetal rhesus isoimmunization, fetal growth restriction, cases with infections detected by maternal serological tests, pregestational or gestational diabetes (All patients underwent a 75-gram glucose load test at 24 weeks to rule out diabetes), preeclampsia, premature rupture of membranes were excluded from the study -

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Screening
Allocation: Non-Randomized
Intervention Model: Sequential Assignment
Interventional Model Description: case control
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: myocardial performance and epicard thickness in obese pregnant women<br>obese pregnant versus normal-weight pregnant women were evaluated for MPI and fetal epicardial thickness | Diagnostic Test: Doppler ultrasonography<br>* Doppler study was performed in all cases. perinatal outcomes were evaluated.<br>|
| Active Comparator: obese pregnant<br>obese pregnant versus normal-weight pregnant women were evaluated for MPI and fetal epicardial thickness | Diagnostic Test: Doppler ultrasonography<br>* Doppler study was performed in all cases. perinatal outcomes were evaluated.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| birth weight (gram) | fetal outcome | birth 1 week | 
| stillbirth rate (%) | fetal outcome | birth 1 week | 
| NICU admission | fetal outcome | 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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obesity,, fetal epicardial thickness, myocardial performance index, perinatal outcome