Treatment of Alopecic Scars by Follicular Unit Extraction Hair Transplantation

Study Overview
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Brief Summary
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This study aim: is to completely hide the alopecic scars in a way that it will not be visible.

Detailed Description
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Practicing scar revision, there is an increasing demand for almost complete reconstruction and camouflaging scars in hairy areas rather than scars in non-hairy skin. Scar revision rendered insufficient reconstructive tool in such cases. Whatever a Plastic surgeon pay efforts in alopecic scars rejuvenation and reconstruction, it is still apparent and noticeable. One of the best surgical techniques to camouflage an alopecic scar is hair transplantation. FUE is the state-of-the-art technique for hair transplantation. In the field of hair restoration, there has been a significant increase in demand with patients for facial hair transplantation procedures. Modern techniques in hair transplantation is based on follicular unit extraction and implantation, in which follicular units are the exclusive structures used as hair grafts allow for facial hair transplantation and for the attainment of natural-appearing results. Facial hair transplantation is a subspecialty within hair restoration with many gratifying benefits for the patients as well as for the hair restoration surgeon. Adapting these advanced techniques into a hair restoration practice allows a surgeon to offer their patients these procedures and provides an expanded artistic element to a hair restoration surgeon's practice. The art and science of hair transplantation have come a long way since its introduction in 1959. Both the technique and instruments have been greatly improved, thus offering the patient an excellent cosmetic result that will last a lifetime.

Official Title
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Definitive Treatment of Alopecic Scars by Follicular Unit Extraction Hair Transplantation, Randomized Prospective Controlled Study

Conditions
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Alopecia Scar

Intervention / Treatment
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* Procedure: follicular unit extraction and implantaion


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: small scalp alopecic scars. post traumatic alopecic beard scars post traumatic alopecic moustache scars. post traumatic alopecic scalp scars. post traumatic alopecic eyebrow scars. post burn small alopecic scars. mature scars. controlled infective scars. Exclusion Criteria: large alopecic scars post burn alaopecic scar uncontrolled active scar male pattern baldness female pattern baldness

Ages Eligible for Study
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Minimum Age: 15 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: To hide alopecic scars with some hairs harvested as FUs at the back of the scalp under local anaesthesia without leaving any residual deformity or adding more scars to the donor area and implant it in the non-hairy scars.
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Mature Alopecic Scars<br>Follicular Unit Extraction and implantation for Alopecic Scars in beard Follicular Unit Extraction and implantation for Alopecic Scars in scalp Follicular Unit Extraction and implantation for Alopecic Scars in eyebrow Follicular Unit Extraction and implantation for Alopecic Scars in Moustache | Procedure: follicular unit extraction and implantaion<br>* extract hair follicles as grafts from donor area and implant them in recipient area<br>|
| Experimental: Immature Alopecic Scars<br>Follicular Unit Extraction and implantation for Alopecic Scars in beard Follicular Unit Extraction and implantation for Alopecic Scars in scalp Follicular Unit Extraction and implantation for Alopecic Scars in eyebrow Follicular Unit Extraction and implantation for Alopecic Scars in Moustache | Procedure: follicular unit extraction and implantaion<br>* extract hair follicles as grafts from donor area and implant them in recipient area<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| evaluating post operative pain using questionnaire | assessment of post operative pain and complications using questionnaire | 6 Month - 1 year | 
| evaluating post operative complications | assessment of post operative pain and complications using questionnaire | 6 Month - 1 year | 
| donor and recipient site assessment | care for recipient as well as donor site using questionnaire | 6 Month - 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Follicular unit growth monitoring | close monitoring for growth of FU growth | monthly up to 1 year | 
| platlet rich plasma injection for FU growth |  | every 2 weeks up to 6 months | 
| number of hairs in each hair follicle |  | every 2 weeks up to 3months |