linjc16/ctgov huggingface dataset:
COVID-19 e Telepsychotherapy: Which Variables Affect Therapeutic Experience?

Study Overview
=================
Brief Summary
-----------------
COVID-19 pandemic forced a widespread adoption of telemedicine, including telepsychotherapy. Telepsychotherapy has been proven to be effective before COVID-19 breakout (Poletti et al., 2020); however, both patients and therapists were skeptical about this modality. The aim of this study is to probe the experience of telepsychotherapy in both patients and therapists, during the COVID-19 lockdown. Thus, when the adoption of online colloquia was mandatory and not an option. Crucially, studying the experience of telepsychotherapy during the COVID-19 pandemic allows i) investigating also the experience of those patients and therapists that were not favorable to this kind of intervention and ii) comparing the experience of therapy in the online and face-to-face modality, in the same patients and therapists. Furthermore, we collect several psychological variables that possibly influence the experience and efficacy of telepsychotherapy (e.g., personality traits, attachment state of mind, previous traumatic experiences) to define the psychological profile behind a favorable or negative experience of telemedicine in both patients and therapists. As crucial novelty, this information is collected in both patients and their therapists, allowing the direct comparisons between the experience of the therapeutic relationship (e.g., empathy, alliance) from two different point of views. The results of the present study may help in the definition of possible subgroups of patients who may be sufficiently responsive to telepsychotherapy and those who may benefit - exclusively - of face-to-face interventions.

Official Title
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COVID-19 e Telepsychotherapy: Which Variables Affect Therapeutic Experience?

Conditions
-----------------
Telepsychotherapy

Intervention / Treatment
-----------------
* Behavioral: Telepsychotherapy


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Licensed and currently practicing psychotherapists Individuals currently undergoing a psychotherapy Exclusion Criteria: not applicable

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 100 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: Telepsychotherapy|Remotely delivered psychotherapy sessions|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Telepsychotherapy perception | Psychometric measures of general perception/experience on the remotely delivered psychotherapy as far as efficacy and interpersonal factors are concerned | At enrollment |
Novel Markers of Disease Progression in Interstitial Lung Disease

Study Overview
=================
Brief Summary
-----------------
Study design: A prospective cohort study with a longitudinal design, with several parameters measured serially at baseline and at pre-specified time points during three to five years of clinical observation. Primary objective: To validate quantitative analysis of lung sounds as a marker of disease progression in a cohort of patients with Interstitial Lung Disease (ILD) via correlation with the extent of fibrosis on HRCT, measured both via visual scoring and quantitative CT assessment, and other validated parameters of disease progression such as FVC, tolerance to exercise and patient-related outcomes (symptoms and quality of life). Secondary objectives: To determine the prognostic value of quantitative analysis of lung sounds and a series of novel putative biological markers, obtained from peripheral blood and bronchoalveolar lavage, toward poor outcomes (death, categorical decline of % predicted FVC >10%, acute exacerbation or respiratory-related hospitalisations) as compared to more conventional clinical, physiology and radiologic measurements.

Official Title
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Novel Markers of Disease Progression in Interstitial Lung Disease

Conditions
-----------------
Interstitial Lung Disease

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: diagnosis of ILD, made according to international guidelines where available age between 40 and 90 years Exclusion Criteria: significant comorbidities or physical impairment that could affect participation

Ages Eligible for Study
-----------------
Minimum Age: 40 Years
Maximum Age: 90 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Disease progression | Validate quantitative analysis of lung sounds as a marker of disease progression via correlation with the extent of fibrosis on HRCT, measured both via visual scoring and quantitative CT assessment, and other validated parameters of disease progression such as FVC, tolerance to exercise and patient-related outcomes. | 3 years |
Prediction Model for TOF

Study Overview
=================
Brief Summary
-----------------
This study was aimed to investigate a prediction model for predicting train-of-four (TOF) 50% in patients undergoing neurosurgery.

Official Title
-----------------
Investigation for Development of Predictive Model for Train of Four (TOF)% for Neurophysiological Monitoring During Neuroanesthesia

Conditions
-----------------
Neurophysiologic Monitoring

Intervention / Treatment
-----------------
* Device: Twitch Electrode Array


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patient undergoing neurosurgery scheduled for intra-operative neurophysiological monitoring American Society of Anesthesiologists physical class I, II, III Exclusion Criteria: unable to monitor train-of-four decline to participate in the study

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Device: Twitch Electrode Array|Monitor train-of-four (TOF) count and percentage|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Train-of-four (TOF) ratio | The ratio of the height of the fourth muscle response to the first one following the nerve stimulation | 30 minutes after reaching the TOF plateau |
The Relationship Between Upper Extremity Explosive Power and Trunk Muscles in Volleyball Players

Study Overview
=================
Brief Summary
-----------------
Volleyball is an interval sport involving consecutive aerobic and anaerobic loads. Strength training based on explosive movements can improve performance in the upper extremities. Strength performance has an important place in this sport. Trunk stabilization is defined as 'proximal stability for distal mobility'. Disorder in any segment of the kinetic chain model will affect the quality of movement in the lower and upper segments.The aim of this study is to examine the relationship between the morphological features of the transversus abdominis, lumbal multifidus (L4-5), internal external oblique muscles, and the anaerobic power of the upper extremity and shoulder girdle functionThis study was designed as a cross-sectional. They will consist of 30 volleyball players between 14-30 years of age. Muscle morphological features of the participants by ultrasound; explosive strength will be evaluated by Medicine Ball Throw test, functional evaluation will be evaluated by Closed Kinetic Chain Upper Extremity Endurance test.

Official Title
-----------------
Voleybolcularda Üst Ekstremite Patlayıcı Güç Ile Gövde Kaslarının Arasındaki İlişkinin İncelenmesi

Conditions
-----------------
Ultrasonography, Upper Extremity, Physical Endurance

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Training for an hour at least 3 days a week for at least 1 year Body Mass Index (BMI) below 30 kg/m2 No concomitant neurological, rheumatological or systemic disease Volunteer to participate in the study. Exclusion Criteria: Having any surgery / serious pathology of the spinal column Having had an upper extremity injury in the last 6 months that would affect his ability to play volleyball Having an injury that requires at least 2 weeks of discontinuation Severe musculoskeletal/systemic discomfort during the measurements.

Ages Eligible for Study
-----------------
Minimum Age: 14 Years
Maximum Age: 30 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Muscle morphology | Morphological characteristics transverse abdominis, lumbar multifidus,internal obliquus, external obliquus will be evaluated via ultrasound imaging | 1 day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Expolsive Power | Medicine Ball Throw | 1 day | 
| Core stability | Sharmannn's Core Stability Test | 1 day | 
| Upper Extremity Endurance | Closed Kinetic Chain Upper Extremity Stability Test | 1 day |
Capabilities of Perinatal Healthcare Institutions in the Federation of Bosnia and Herzegovina

Study Overview
=================
Brief Summary
-----------------
The aim of this study is to assess the level of the perinatal healthcare institution (PHI) where the newborns were delivered. We included newborns of both genders that were born in the maternity wards in 10 cantons of the Federation of Bosnia and Herzegovina (FBiH). From the PHI of the first and second level, 159 newborns were referred to the third level. Out of a total of 159 LBWI referred from other PHI, only 19.5% LBWI were transported in less than 4 hours. In second level PHI, most LBWI died in the first 12 hours after birth.

Official Title
-----------------
Capabilities of Perinatal Healthcare Institutions in Primary and Tertiary Care of Low Birth Weight Infants in the Federation of Bosnia and Herzegovina: A Cross-sectional Multicentric Study.

Conditions
-----------------
Prenatal Care

Intervention / Treatment
-----------------
* Other: Referral to Centre of Higher Organizational Level


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Newborns of both genders that were born in the maternity wards in 10 cantons of the FBiH A gestational age between 22 and 42 weeks, and a birth weight less than 2500g. Exclusion Criteria: Infants younger than 22 weeks or older than 42 weeks. Infants whose mothers refused to give consent for participation in the study.

Ages Eligible for Study
-----------------
Minimum Age: 22 Weeks
Maximum Age: 42 Weeks

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Referred to a Centre of Higher Level<br>Those are the newborns that were referred at the time of delivery or within one week after birth to centers of higher organizational level. | Other: Referral to Centre of Higher Organizational Level<br>* Referral to Centre of Higher Organizational Level. This means referral from a primary neonatal care center to a secondary one, or from the secondary to the tertiary center.<br>|
| Treated at the Centre of Admission<br>Those are the newborns that were not referred to other centers and were treated in the health facility were the birth took place, and hospitalized in the same center until discharge. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Referral to a centre of higher organizational level. | Referring the neonate with low birth weight to a more specialized centre. | Before birth and up to 4 hours or more after delivery. |
Evaluation of the Predictive Role of Choline PET/CT on the Survival of Patients Affected by Prostate Cancer.

Study Overview
=================
Brief Summary
-----------------
the increase in the serum PSA (prostate specific antigen) value following radical treatment commonly involves subsequent treatment which, in the absence of morphological evidence of disease recovery, is conducted empirically through local radiotherapy or systemic hormonal therapy. The use of PET with choline is therefore of extreme clinical interest as it allows to identify the site of disease recurrence, thus being able to direct towards a specific therapeutic treatment. The diagnostic accuracy of choline PET in identifying the location of the disease has been widely demonstrated in the literature and is comparable to those of conventional diagnostic methods previously described for the restaging of patients with prostatic disease. The real advantage of this method is the possibility of obtaining the same information as conventional methods by carrying out a single exam.

Official Title
-----------------
Evaluation of the Predictive Role of Choline PET/CT on the Survival of Patients Affected by Prostate Cancer.

Conditions
-----------------
Prostate Cancer

Intervention / Treatment
-----------------
* Diagnostic Test: Diagnostic accuracy


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: adult patients suffering from prostate cancer who have undergone choline PET/TC Exclusion Criteria: patients < 18 years

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
Male

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: Diagnostic accuracy|The PET CT study with choline, being part of the normal standard diagnostic work-up of the patients, was performed following the normal clinical protocol. By analyzing the data retrospectively, the time elapsed following the prostatectomy operation and the follow up time after the choline PETCT study will be evaluated.|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Choline PET-CT for the restaging of patients with prostatic disease. | By analyzing the data retrospectively, the time elapsed following the prostatectomy operation and the follow up time after the choline PETCT study will be evaluated. | 1 year |
A Multi-omics-based Metabolic Typing Study of Gastric Cancer

Study Overview
=================
Brief Summary
-----------------
In the study, the investigators obtained gastric cancer tissues from 480 gastric cancer patients who had undergone surgery at the Zhejiang Cancer Hospital's biospecimen bank between 2012-2019, and obtained relevant clinical information. The gastric cancer tissues were subjected to transcriptomic, metabolomic and other multi-omics testing, and analyzed for the metabolic changes of gastric cancer, and proposed to discover relevant therapeutic targets.

Official Title
-----------------
Clinical Study on Metabolic Typing of Gastric Cancer Based on Transcriptome, Metabolome and Other Multi-omics

Conditions
-----------------
Gastric Cancer, Multi-omics, Diagnosis

Intervention / Treatment
-----------------
* Other: Without any intervention


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 18≤age≤80 Histologically or cytologically confirmed gastric cancer Undergo surgery for radical or palliative gastric cancer (both open and laparoscopic) Patients with survival follow-up information Exclusion Criteria: Two or more kinds of malignant tumors at the same time Incomplete or missing case information Preoperative diagnosis of residual gastric cancer

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Cancer tissues<br> | Other: Without any intervention<br>* There were no special interventions for the two groups.<br>|
| Normal adjacent tissues<br> | Other: Without any intervention<br>* There were no special interventions for the two groups.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The differences of the metabolism information | The differences of the metabolism information between gastric cancer tissues and non-cancerous gastric cancer tissues. These data included Metabolizing enzyme mRNA expression and metabolite content. | through study completion, an average of 6 months |
INTERFACE: hIv patieNts TracER For clinicAl assistanCe and rEsearch During COVID 19

Study Overview
=================
Brief Summary
-----------------
The health emergency related to the SARS CoV2 pandemic has highlighted the problems of health management of patients at risk of COVID19 and with chronic diseases, suggesting the need for new methods of patient monitoring. Teleconsultation, and telemedicine in general, are applications that allow, at these times when access to hospitals is by definition limited, to monitor patients with chronic conditions who need regular and consistent care and monitoring. People living with HIV/AIDS (PLWHA) represent a paradigm of chronic patients on whom the development of e-health-based remote monitoring could have a significant impact in terms of maintaining an adequate standard of care. For these reasons, in a large teaching hospital we are planning the creation and use of an application to enable remote monitoring of PLWHA by combining the COVID19 prescreening system and chronicity monitoring.

Official Title
-----------------
INTERFACE: hIv patieNts TracER For clinicAl assistanCe and rEsearch During COVID 19 Epidemic: a Paradigm for Chronic Conditions

Conditions
-----------------
HIV Infections

Intervention / Treatment
-----------------
* Device: Device


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion criteria: Age of patients>18 years. Patients able to use apps and smart devices without caregivers or, if the patient is unable to use them, patients with caregivers able to use apps and smart devices. Able to provide informed consent Exclusion criteria: Patients unable to use smart devices and apps without the presence of caregivers - Recent diagnosis of HIV infection (<3 months) Any unstable clinical condition requiring hospitalization

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Device: Device|To develop an e-health system to remotely monitor patients with chronic HIV infection and conduct early screening for COVID-19 through a telemonitoring, teleconsultation and periodic remote visit system.|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| A new model for patient follow-up | Develop an e-health system to remotely monitor patients with chronic HIV infection and conduct early screening for COVID-19 through a system of telemonitoring, teleconsultation and periodic remote visits. | 1 year |
Unwinding Anxiety for Migraine: Pilot

Study Overview
=================
Brief Summary
-----------------
This is a pilot study that aims to understand the feasibility and acceptability of a mobile health educational app plus group-based mindfulness therapy on anxiety and migraine-related disability among people with migraine.

Official Title
-----------------
Unwinding Anxiety for Migraine: Pilot

Conditions
-----------------
Migraine, Anxiousness

Intervention / Treatment
-----------------
* Behavioral: Unwinding Anxiety


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 18 or older Meets diagnostic criteria for migraine Reports anxiety symptoms of 5 or more on GAD-7 Has a smartphone Exclusion Criteria: Under the age of 18 Presence of suicidal ideation Reports severe depression on PHQ-9 Lack of group readiness

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Unwinding Anxiety<br> | Behavioral: Unwinding Anxiety<br>* In the Unwinding Anxiety arm, participants will receive 6 weeks of an educational app and weekly facilitated mindfulness groups.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Feasibility | Average number of facilitated mindfulness group sessions attended out of 6 weekly sessions | 6 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Acceptability | Average Credibility Score from the Credibility/Expectancy Questionnaire [min = 3; max = 27; higher scores indicate higher credibility] | Assessed at 6 weeks, immediately post-intervention |