The Effect Of Medical Nutritional Therapy On Patients With Sarcopenic Obesity Requesting Peritone Dialysis Treatment

Study Overview
=================
Brief Summary
-----------------
In this study, it was aimed to evaluate the effectiveness of medical nutrition therapy to be applied to patients with sarcopenic obesity receiving peritoneal dialysis treatment by measuring anthropometric measurements and blood parameters.

Detailed Description
-----------------
Efficacy of medical nutrition therapy in patients with saecopenic obesity receiving peritoneal dialysis treatment, general information form after patients filled in the voluntary consent form, SARC-F questionnaire as sarcopenia screening test, International Physical Activity Questionnaire (IPAQ), muscle mass, muscle strength, physical performance, BIA measurement, anthropometric measurements, laboratory findings and three-day food consumption records will be evaluated.

Official Title
-----------------
The Effect of Medical Nutrition Therapy on Anthropometric Measurements and Blood Parameters in Sarcopenic Obesity Patients Undergoing Peritoneal Dialysis Treatment

Conditions
-----------------
Peritoneal Dialysis Complication, Sarcopenic Obesity

Intervention / Treatment
-----------------
* Other: medical nutrition therapy in kidney diseases


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Volunteering to participate in research Be between the ages of 18-70 To receive peritoneal dialysis treatment and to come to the hospital regularly once a month for treatment Exclusion Criteria: Presence of any other disease that causes muscle wasting Patients using any supplement or enteral product in their diet

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Dietary and Behavioral Change Group<br>The experimental group will be required to adhere to a diet consisting of a 10-15% reduction in carbohydrate and a 1.2-1.4 g/kg body weight/day intake of protein. The participants will receive 4 times face-to-face meetings (on the first day and on week 1,5 and 9). Each face-to-face interview will last approximately 30 minutes. During the interview researcher will help the participants to determine their nutritional behaviors, plan and implement the diet. | Other: medical nutrition therapy in kidney diseases<br>* Planning and implementation of diets containing high protein, low potassium, low phosphorus, personalized adjusted carbohydrates<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in muscle strength | Handgrip strength (kg) will be measured by using the CAMRY EH101 dynamometer. Hand grip strength <16 kg for women and <27 kg for men indicates low muscle strength. | Baseline to 3 months after diet programme | 
| Change in the skeletal muscle mass | Skeletal muscle mass (kg) will be measured by using bioelectrical impedance analysis. | Baseline to 3 months after diet programme | 
| Change in the physical performance | 4-meter walking speed test will be performed. A walking speed of ≤0.8 m/sec is considered as an indicator of severe sarcopenia. | Baseline to 3 months after diet programme | 
| Change of the fat mass | Fat mass (kg) will be measured by using bioelectrical impedance analysis. | Baseline to 3 months after diet programme | 
| Changes of percentage of body fat | Percentage of body fat will be measured by using bioelectrical impedance analysis. | Baseline to 3 months after diet programme | 
| Changes of body mass index | The weight and height will be combined to report BMI in kg/m2. | Baseline to 3 months after diet programme |