Effect of Yoga Breathing Exercises Versus Aerobic Exercise on Hematological Parameters

Study Overview
=================
Brief Summary
-----------------
Is there effect of yoga breathing exercises versus aerobic exercise on hematological parameters in iron deficiency anemic females? The purpose of the study is to investigate the effect of yoga breathing exercises versus aerobic exercise on hematological parameters in iron deficiency anemic females

Detailed Description
-----------------
60 patients with iron deficiency anemia and will receive medical treatment of anemia and Dietary advice for 12 weeks . thirty patient from the 60 patients will receive yoga therapy and 50 minutes yoga therapy 6 days a week for 12 weeks while the other 30 patients will receive aerobic exercise for 12 weeks

Official Title
-----------------
The Effect of Yoga Breathing Exercises Versus Aerobic Exercise on Hematological Parameters in Iron Deficiency Anemic Females

Conditions
-----------------
Iron Deficiency Anemia

Intervention / Treatment
-----------------
* Other: Yuga
* Other: Aerobic exercises


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Sixty female patients referred with iron deficiency anemia Their age will be ranged from 30-40 years old. All patients have a history of anemia. All patients should be medically stable. The body mass index (BMI) ranged from 25:29.9 Kg/m2 Number of parity not exceed 3 times. Period of menses from 3-5 days Exclusion Criteria: Patients with cognitive impairments. All types of anemia except iron deficiency anemia patients with hearing problems. patients with Diabetes, Hypertension. Patients with Musculoskeletal, Neurological, Cardiovascular and Respiratory problems patients with mental problems.

Ages Eligible for Study
-----------------
Minimum Age: 30 Years
Maximum Age: 40 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Group (I)<br>consists of 30 patients with iron deficiency anemia and will receive medical treatment of anemia, Dietary advices and 50 minutes yoga therapy 6 days a week for 12 weeks | Other: Yuga<br>* Traditional yoga body posture for 15 minutes, yoga breathing exercises for 30 minutes and meditation for 5 minutes for 12 weeks<br>|
| Other: Group (II)<br>consists of 30 patients with iron deficiency anemia and will receive medical treatment for anemia, Diet advices and 30 minutes of aerobic exercises in form of treadmill according to the target exercise heart rate for 12 weeks. | Other: Aerobic exercises<br>* in form of treadmill according to the target exercise heart rate for 12 weeks<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| serum iron level | it will be measured in serum from complete blood picture. Reference range from 50 till 212 ug/dl. Number of participants are 60 females. | it will be measured after 12 weeks | 
| ferritin level | it will be measured in serum from iron profile. Reference range from 10 till 158 ng/ml. Number of participants are 60 females. | it will be measured after 12 weeks | 
| iron binding capacity level | it will be measured in serum from iron profile. Reference range from 250 till 400 ug/dl. Number of participants are 60 females. | it will be measured after 12 weeks | 
| count of red blood cells | it will be measured in serum from complete blood picture. Reference range from 3.80 till 4.80 million cell/cmm. Number of participants are 60 females. | it will be measured after 12 weeks | 
| Hemoglobin level | it will be measured in serum from complete blood . picture. Reference range from 12 till 15 g/dl. Number of participants are 60 females. | it will be measured after 12 weeks | 
| hematocrite level | it will be measured in serum from complete blood picture. Reference range from 36% till 45%. Number of participants are 60 females. | it will be measured after 12 weeks | 
| lymphocytes level | it will be measured in serum from differential white cell count. Reference range absolute from 1000 till 4000 and relative from 20% till 45%. Number of participants are 60 females. | it will be measured after 12 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| six minute walking distance | The six minute walking distance is measured using six Minute Walk Test which is a sub-maximal exercise test used to assess aerobic capacity and endurance. The distance covered over a time of 6 minutes is used as the outcome by which to compare changes in performance capacity. The tools are used include 30 meters corridor,2 cones,stopwatch,chair,mechanical lap counter and sphygmomanometer Number of participants are 60 females. | it will be measured after 12 weeks | 
| The fatigue severity scale(FSS) | The FSS questionnaire contains nine statements that rate the severity of your fatigue symptoms. Read each statement and circle a number from 1 to 7, based on how accurately it reflects your condition during the past week and the extent to which you agree or disagree that the statement applies to you. A total score of less than 36 suggests that you may not be suffering from fatigue. A total score of 36 or more suggests that you may need further evaluation by a physician. Number of participants are 60 females. | it will be measured after 12 weeks |