Transcranial Direct Current Stimulation (tDCS) on Working Memory in College Going Students

Study Overview
=================
Brief Summary
-----------------
Working memory deficiencies, might make it difficult for students to recall instructions, complete complex activities, and grasp and follow directions solving a math problem or writing a sentence. The functions of working memory are critical for effective human activity. Transcranial direct current stimulation (tDCS) has grown in popularity and academic interest in recent years as a way to improve cognitive abilities. so there is need to determine the effect of tdcs on working memory in college going students.

Official Title
-----------------
Efficacy of Transcranial Direct Current Stimulation (tDCS) on Working Memory in College Going Students

Conditions
-----------------
Working Memory Deficits

Intervention / Treatment
-----------------
* Device: Transcranial direct current stimulation (tDCS)


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: College going students Both male and female Able to follow verbal commands Exclusion Criteria: Chronic skin problems. Seizure and any neurological disorder Any recent trauma or surgery Any cardiovascular or pulmonary disease Psychosomatic disorders

Ages Eligible for Study
-----------------
Minimum Age: 17 Years
Maximum Age: 25 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: experimental<br>Transcranial direct current stimulation will use to deliver a constant direct current through two surface electrodes, Anodal stimulation will applied according to the 10-20 international system for EEG electrode placement, over F3 of the dorsolateral prefrontal cortex (DLPFC), while the cathode will placed over the contralateral supraorbital area with 1.5 ma intensity for 20 min with working memory task on alternate days for two weeks. | Device: Transcranial direct current stimulation (tDCS)<br>* Transcranial direct current stimulation will use to deliver a constant direct current through two surface electrodes, Anodal stimulation was applied according to the 10-20 international system for EEG electrode placement, over F3 of the dorsolateral prefrontal cortex (DLPFC), while the cathode was placed over the contralateral supraorbital area for 20 min, on alternate days for 2 weeks 6 sessions with working memory training task. the anode (positive) and the cathode (negative). To reduce resistance and minimize discomfort during application (the electrodes were covered in 35 cm2, saline-soaked sponges<br>* Other names: working memory training task;|
| No Intervention: memory task training group<br>working memory task training for 20 min for two weeks | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Trail making test | As the participant proceeds in an increasing sequence, he or she must alternate between numbers and letters. Subjects are challenged to link numbers and alphabets as quickly as possible. The examiner calls out errors as they happen so that the subject can finish the test without making any mistakes | changes between baseline to 2 weeks | 
| Digit span test | Digit Span Forward requires the child to repeat numbers in the same order as read aloud by the examiner, and Digit Span Backward requires the child to repeat the numbers in the reverse order of that presented by the examiner. | changes between baseline to 2 weeks | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
working memory, immediate memory