Cancer Survivorship in Hematologic Malignancies

Study Overview
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Brief Summary
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General objective: to improve care for haematological cancer survivors. This study will (i) Estimate the incidence of cancer survivor syndrome (CSS) in adult Egyptian patients with haematological neoplasms (HN). (ii) Asses the risk factors of CSS in patients with HN. (iii) Study the effect of CSS on quality of life in patients with HN. (iv) To explore coping strategies of patients with HN having CSS

Detailed Description
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According to the American Cancer Society the term cancer survivor refersto people who have no signs of cancer after finishing treatment, people receiving extended treatment over a longer period of time to control the cancer or reduce risk of its return, and people with advanced cancer. Most hematologic malignancies (HM) are incurable and typically follow unpredictable remitting-relapsing pathways associated with varying need for treatment, which may be distressing for patients. Distress symptoms and psychological disorders secondary to cancer have also been shown to have significant negative consequences for both the patient and the family. Maladaptive coping and abnormal illness behavior have been associated with psychiatric conditions, with negative effects on adherence to treatment, health behavior, and quality of life (Grassi et al 2017). Moreover, an increased length of stay in the hospital and/or an increased time in rehabilitation have been found to be more common among patients showing psychiatric symptoms, especially depression, than those with normal adjustment to illness (Cordova et al 2017). Unfortunately, cancer-related distress is commonly underrecognized and subsequently undertreated especially for patients with HM in developing countries. Search in literature revealed several screening methods for the psychological consequences of cancer such as Distress Thermometer , Symptom related checklist questionnaire, Quality of life questionnaire, Coping strategies questionnaire. Also, guidelines for the management of psychological distress have been developed by several scientific cancer associations.

Official Title
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A Comprehensive Study of Cancer Survivor Syndrome in Adult Egyptian Patients With Hematological Neoplasms

Conditions
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Cancer Survivors

Intervention / Treatment
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* Other: questionnaire


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: a. Inclusion criteria: Age will be more than or equal 18 years old regardless with six. Patients have been clinically diagnosed with haematological cancers. Being Native Egyptian patients. Exclusion Criteria: History of psychiatric disorders. b) Having other concomitant haematological diseases or solid neoplasm or relapse or other chronic disorders

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Myloid group<br>Patients diagnosed as Multiple Myeloma, treated, and not in relapse | Other: questionnaire<br>* The symptom related checklist questionnaire, Quality of life questionnaire, Coping strategies questionnaire, Distress thermometer<br>|
| Lymphoid group<br>Patients diagnosed as having lymphoma, treated, and not in relapse | Other: questionnaire<br>* The symptom related checklist questionnaire, Quality of life questionnaire, Coping strategies questionnaire, Distress thermometer<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The incidence of cancer survivor syndrome (CSS) | Estimate the incidence of cancer survivor syndrome (CSS) in adult Egyptian patients with hematological neoplasm neoplasms (HN) | 2 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Asses the risk factors of CSS | Asses the risk factors of CSS in adult Egyptian patients with hematological neoplasm neoplasms (HN) | 2 years | 
| Study the effect of CSS on quality of life | Study the effect of CSS on quality of life in adult Egyptian patients with hematological neoplasm neoplasms (HN) | 2 years | 
| Exploring coping strategies | To explore coping strategies of adult Egyptian patients with hematological neoplasm neoplasms (HN) in CSS. | 2 years |