An Evaluation Of Healthy Ankle Motion And Morphology

Study Overview
=================
Brief Summary
-----------------
Determine motion and morphology of the healthy ankle during simulated gait.

Detailed Description
-----------------
Healthy volunteers will undergo weight-bearing, cone beam CT scans of their foot/ankle during 3 phases of simulated gait. Motion and morphology of the foot and ankle will be quantified and analyzed.

Official Title
-----------------
An Evaluation Of Healthy Ankle Motion And Morphology In Different Phases Of Simulated Gait Using A Weight-bearing CBCT Scan

Conditions
-----------------
Healthy Ankle

Intervention / Treatment
-----------------
* Radiation: Cone Beam Computed Tomography
* Radiation: Radiographs


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: The subject self-reports having a right healthy ankle. The subject agrees to comply with the requirements of the study and complete the study measures. The subject is between the ages of 18 and 65. The subject is willing to provided written informed consent. Exclusion Criteria: The subject is pregnant. The subject reports having been diagnosed with any form of diabetes. The subject reports having surgery on the right foot, right ankle and/or right knee. The subject reports a history of repeated ankle sprains or injuries to the right ankle. The subject reports a history of instability of the right ankle. The subject reports chronic or recurring pain of the right ankle. The subject is: a prisoner, unable to understand what participation in the study entails, mentally incompetent, and/or known abuser of alcohol and/or drugs.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Healthy<br>Subjects identified to have a healthy foot/ankle | Radiation: Cone Beam Computed Tomography<br>* Computer tomography (CT) of the foot/ankle for determination of motion and morphology<br>Radiation: Radiographs<br>* Standard radiographs of the foot/ankle as part of the screening criteria<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Relative rotations of bones | Determine relative tri-axial rotations between bones of the foot and ankle using reconstructed 3-dimensional computer models. All rotations will be measured in degrees (°). | 1 day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Relative translations of bones | Determine relative multi-directional translation between bones of the foot and ankle using reconstructed 3-dimensional computer models. All translations will be measured in mm. | 1 day | 
| Morphology - size and shape of the bones of the foot and ankle | Evaluate the size and shape of the bones of the foot and ankle using reconstructed 3-dimensional computer models relative to height, weight, body mass index and gender. All distances will be measured in mm. | 1 day | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
ankle