Parameters of Neurological Deficit After Thoracolumbar Fractures

Study Overview
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Brief Summary
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To detect Radiological parameters affecting neurological injury after thoracolumbar spinal fractures.

Detailed Description
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Thoracolumbar spine fractures are the most common spinal column fractures. High activity and lack of stability make it more prone to fractures. Many studies have attempted to determine whether the neurological deficit in such fractures is related to spinal canal stenosis or other parameters observed on axial computed tomography (CT). However, this relationship remains controversial. Few reports shed light on the relation between different imaging parameters like sagittal alignment, vertebral body compression, canal stenosis, and type of fracture according to AO classification with the severity of nerve damage. These four radiographic parameters will be tested as expected risk factors for the neurological deficit in thoracolumbar fractures.

Official Title
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Radiological Parameters Predicting Neurological Injury After Thoracolumbar Spinal Fractures

Conditions
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SPINAL Fracture

Intervention / Treatment
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* Radiation: computed tomography


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Any patient with Acute (within one month) thoracolumbar spine fracture above 18 years old with or without neurological deficit In orthopaedics and trauma department of Assiut university hospital from 1st of November 2018 to 31 st of October 2019. Exclusion Criteria: Patients younger than 18 years old. Patients suffering from preoperative neurological diseases that hinder our examination like peripheral neuropathy or previous strokes. Obtuned patients who cannot be properly examined like those with low GCS score. Patients with old thoracolumbar fractures more than one month duration. Patients with pathological spine fractures like those with osteoporosis and cancer metastasis. Patients with fracture type A0 according to AO classification.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Radiation: computed tomography|ct will be done to detect radiological risk factors for neurological deficits after thoracolumbar fractures|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To Measure spinal canal stenosis by cubic cm | CT-Radiological parameters measured in patients with or without thoracolumbar fractures . | one year | 
| To measure sagittal alignment of vertebral column by cobb angle | CT-Radiological parameters measured in patients with or without thoracolumbar fractures | one year | 
| To measure vertebral body compression by cm | CT-Radiological parameters measured in patients with or without thoracolumbar fractures | one year | 
| To measure type of fracture according to AO classification | CT-Radiological parameters measured in patients with or without thoracolumbar fractures | one year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Proportion of Neurological deficit among patients with thoracolumbar spine fractures. | Number of patients with neurological deficit to the total number of patients with thoracolumbar spine fractures. | one year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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neurological deficit