3D Printed Donor Tooth Replica in Autotransplantation of Teeth

Study Overview
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Brief Summary
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3D printed replicas of the donor tooth can reduce extraoral time during the autotransplantation of teeth, which can reduce dehydration and manipulation of periodontal tissue of the donor tooth, thus possibly increasing the success rate.

Detailed Description
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This technique of autotransplantation has been innovated using 3-dimensional (3D) imaging and rapid prototyping.The use of a 3D-printed replica of the donor tooth is thought to minimize the risk of iatrogenic damage to the actual donor tooth. Nevertheless, no large prospective and comparative studies are available to assess the outcomes using these 3D techniques. Therefore, this study aimed to compare 3D printed replicas in autotransplantation of teeth, compared to the conventional technique. The present study will evaluate the feasibility, clinical satisfied accuracy, and stability of a novel approach for computer-aided autotransplantation of teeth. This new approach facilitated the surgical procedure and might be a viable and predictable method for autotransplantation of teeth. Application of printed 3D replicas of transplanted teeth facilitates surgical preparation of the recipient site, shortens the extra-alveolar time, and reduces the minimum the number of attempts of the donor tooth insertion at the prepared socket. Their use can significantly decrease the risk of damage to the root surface of a transplant, thus increasing the chance of success.

Official Title
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3D Printed Donor Tooth Replica in Autotransplantation of Teeth. A Randomized Clinical Trial.

Conditions
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Decayed Teeth

Intervention / Treatment
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* Procedure: 3D printed replica of the donor tooth
* Procedure: Conventional Autotransplantation of tooth


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patient presenting with decayed first molars autotransplantation of third molar at the recipient site Exclusion Criteria: Diabetic, pregnant patients other autotransplantations (other than first molar recipient and third molar donor)

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Parallel randomized controlled tria
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 3D printed replica of Donor tooth<br>3D printed replica of Donor tooth | Procedure: 3D printed replica of the donor tooth<br>* 3D printed replica of the donor tooth.<br>|
| Active Comparator: Conventional<br>Conventional method of autotransplantation. | Procedure: Conventional Autotransplantation of tooth<br>* Conventional Autotransplantation of tooth without using the 3D printed guide<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of teeth that fail | reduced mobility (less than grade II) after 2 weeks of autotransplantation | two weeks | 
| Operative time | Operative time from the start of socket preparation at the recipient site | 1 day | 
| Rate of Ankylosis (replacement resorption) | Ankylosis (replacement resorption) | 6 months | 
| Rate of root resorption | infection related root resorption | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cost difference of the treatment | Cost of 3D printing | 1 day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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decayed teeth; autotransplantation; 3d printing