The Evaluation Of Bone Width Gain Following Split Crest Technique With Or Without Platelet Rich Fibrin( PRF)

Study Overview
=================
Brief Summary
-----------------
Split crest technique is a technique for horizontal bone augmentation used in case of narrow alveolar ridges as an alternative to the more aggressive techniques such as onlay bone grafting, guided bone regeneration (GBR) and distraction osteogenesis The study goal is to evaluate whether if there will be any benefit of using platelet rich fibrin (PRF) with the split crest technique regarding bone width gain and healing response in comparison with split crest technique alone, where PRF is considered an autologous, growth factor containing material which is easy to collect and is of low cost.

Official Title
-----------------
The Evaluation Of Bone Width Gain Following Split Crest Technique With Or Without PRF In Conjunction With Simultaneous Implant Placement In Narrow Alveolar Ridges: A Randomized Controlled Clinical Trial

Conditions
-----------------
Ridge Deficiency

Intervention / Treatment
-----------------
* Procedure: Split Crest with PRF
* Procedure: Split Crest without PRF


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with at least one missing tooth in the maxillary region All the selected patients have a bucco-palatal width of the edentulous alveolar ridge from 3.5-5.5mm. All the selected patients have at least 12 mm residual bone height at the edentulous area The recipient site of the implant should be free from any pathological conditions. No diagnosed bone disease or medication known to affect bone metabolism. Patients who are cooperative, motivated, and hygiene conscious. Exclusion Criteria: Patients unable to undergo minor oral surgical procedures. Patients with a history of drug abuse or catabolic drugs. Patients with a history of psychiatric disorder. Patients with unrealistic expectations about the esthetic outcome of implant therapy. Patients with insufficient vertical inter-arch space, upon centric occlusion, to accommodate the available restorative components. Patients in the growth stage with partially erupted teeth. Patients who have any systemic condition that may contraindicate implant therapy. Patients who have any habits that might jeopardize the osseointegration process, such as smoking and alcoholism. Patients with parafunctional habits that produce overload on the implant, such as bruxism and clenching.

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Control Arm<br>Split crest without PRF | Procedure: Split Crest without PRF<br>* Narrow ridges are split to increase the ridge width and immediate implants are placed without grafting<br>|
| Experimental: Intervention Arm<br>Split crest with PRF | Procedure: Split Crest with PRF<br>* Narrow ridges are split to increase the ridge width and immediate implants are placed with PRF closing the gap<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bone width gain |  | 6 months |