Occupational and Environmental Origins of ANCA Vasculitis: Contribution of Data From the National Network for Vigilance and Prevention of Occupational Pathologies (RNV3P)

Study Overview
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Brief Summary
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The main objective is to identify specific risk factors for ANCA vasculitis of occupational and/or environmental origin (exposures identified by questioning, geographical distribution of cases) from the RNV3P data. The secondary objectives are as follows: Description of cases of ANCA vasculitis seen in French occupational pathology consultation centres: reasons for consultation, occupational and environmental etiologies described occupational situations responsible aptitude notices recognition as an occupational disease Identification of specific risk factors for ANCA vasculitis of occupational and/or environmental origin (exposures identified on questioning, geographical distribution of cases). For occupational and non-occupational cases of ANCA vasculitis: identification of difficulties encountered by patients at work and proposed work adaptations. Estimation of the number of applications for recognition of disabled worker status made within this patient group. Identification of clinical severity and autoimmune profiles of ANCA vasculitis of occupational and/or environmental origin.

Official Title
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Occupational and Environmental Origins of ANCA Vasculitis: Contribution of Data From the National Network for Vigilance and Prevention of Occupational Pathologies (RNV3P)

Conditions
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ANCA Associated Vasculitis, Occupational Diseases, Environmental Exposure

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patient with ANCA vasculitis defined according to the International Classification of Diseases (ICD-10), i.e. M 308, M 31, N 057 and L 95, or mentioned as the reason for consultation in the text mining summary. Seen in consultation in the occupational disease consultation centres belonging to the RNV3P No opposition Exclusion Criteria: Refusal to participate

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of diagnoses of ANCA vasculitis in the RNV3P | Number of diagnoses of ANCA vasculitis coded in the RNV3P or mentioned as the disease motivating the consultation in the summary by text mining search. | 4 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Imputability of the coded diagnoses of ANCA vasculitis. | Number of patients with ANCA vasculitis seen in consultation in occupational disease consultation centres for which a link between occupational and/or environmental exposure and the patient's ANCA vasculitis was retained. The imputability is coded in the RNV3P database by the clinician who saw the patient, for each exposure recorded in the database, according to the pathology selected and the patient's exposure following the completion of the patient's laboris and environmental curriculum. | 4 months | 
| Number of patients with ANCA vasculitis for whom occupational and/or environmental exposure to microcrystalline silica was identified. | Number of patients with ANCA vasculitis seen in consultation in occupational disease consultation centres for whom occupational and/or environmental exposure to microcrystalline silica was identified. | 4 months | 
| Number of patients with ANCA vasculitis for whom other occupational and/or environmental exposure was identified. | Number of patients with ANCA vasculitis seen in consultation in occupational disease consultation centres for whom other occupational and/or environmental exposure was identified. | 4 months | 
| Number of patients with ANCA vasculitis for whom an application for recognition as a disabled worker has been submitted. | Number of patients with ANCA vasculitis seen in consultation in occupational disease consultation centres for whom an application for recognition as a disabled worker has been submitted. | 4 months |