Prevalence, Etiology and Therapy of Micturition Disorders of Children With a Mental and/or Motoric Disability

Study Overview
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Brief Summary
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Investigation of the prevalence etiology and therapy of micturition disorders of children with a mental and/or motoric disability

Detailed Description
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Overview of the problem by a questionnaire, diary of micturition and drinking behaviour, filled out by the parents or by the staff of the institution. Investigation of the etiology by clinical and functional examination (uroflowmetry, bladder scan, video-urodynamic examination). Frequency: Uroflowmetry: two periods of two weeks, with 6 weeks break between both periods. During the follow-up period every 3 months during 12 months Bladder scan: once during the periods of the uroflowmetry Video-urodynamic examination: once in selected participants, after consent of the parents Adaptation of the drinking behaviour: start after two weeks of observation, after uroflowmetry and bladder scan. Continuous proces. Therapeutic measures (medication, miction clock): start after 10 weeks of observation or after video-urodynamic examination. Development of a therapeutic plan: adaptation of the micturition and drinking behaviour, anticholinergic therapy.

Official Title
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Prevalence, Etiology and Therapy of Micturition Disorders of Children With a Mental and/or Motoric Disability

Conditions
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Micturition Disorder

Intervention / Treatment
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* Procedure: Questionnaire and micturition and drinking diaries
* Procedure: Clinical and functional examination (uroflowmetry, bladder scan and video-urodynamic examination)
* Behavioral: Adaptation of the drinking scheme
* Drug: Anticholinergic therapy
* Behavioral: Micturition clock


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Children with a motoric and/or mental disability 4-14 years Exclusion Criteria: Known neurogenic bladder disorder

Ages Eligible for Study
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Minimum Age: 4 Years
Maximum Age: 14 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: Questionnaire and micturition and drinking diaries|nan|
|Procedure: Clinical and functional examination (uroflowmetry, bladder scan and video-urodynamic examination)|nan|
|Behavioral: Adaptation of the drinking scheme|nan|
|Drug: Anticholinergic therapy|nan|
|Behavioral: Micturition clock|nan|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prevalence of micturition disorders |  |  | 
| Etiology of micturition disorders after 10 weeks observation |  |  | 
| Influence of drinking scheme on bladder capacity and micturition continence after 10 weeks observation |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Efficacy of the therapy after 3, 6, 9, 12 months |  |  |