Pilot Voice Sample Collection From People With Asthma

Study Overview
=================
Brief Summary
-----------------
Human speech is as unique as a fingerprint and analysing speech had advanced so much that speech can now be used instead of PIN numbers in banking. The investigators want to find out whether changes in everyday speech can signal the worsening of asthma. The investigators are planning to collect voice samples from people as their asthma gets better and worse in order to analyse the changes in voice quality - if any. The participants donating the voice samples will remain anonymous and the voice files will be transferred securely to our analytic system.

Detailed Description
-----------------
Over 18 users of the Smart Asthma app (by Smart Respiratory Products Ltd) will be asked if they wish to participate in the study by recording voice samples. The question will be posed within the app and can be answered with a tap. Those interested in participating will be shown a short plain English description of the goals and methodology of the project before enrolled. A maximum of 9 voice sample recording session will be carried out on the phones of participants and take less than 2 minutes each, so participants will spend a total of fewer than 18 minutes during the entire trial. Sessions will be offered after participants have recorded their asthma symptoms, lung function and inhaler use in the normal course of using the app. Participants may accept or decline each individual offer to record their voice. Participants will have a chance to play each voice recording before sharing it anonymously with the investigators. Participants can discontinue their participation at any time and can ask investigators to delete all their data. The investigators will be analyse collected voice samples for changes in voice quality. The changes in voice quality will be compared against changes in lung function and asthma symptoms to determine what changes in voice quality, if any, are indicative of a change in asthma control.

Official Title
-----------------
Collecting Anonymous Voice Samples From Users of the Smart Asthma App

Conditions
-----------------
Asthma Chronic

Intervention / Treatment
-----------------
* Other: Recording voice samples


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Current user of the Smart Asthma app Over 18 Volunteers to participate Agrees to terms Exclusion Criteria: None

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 99 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Participants<br>Current user of the Smart Asthma app | Other: Recording voice samples<br>* A maximum of 9 voice sample recording session will be carried out on their phones and take less than 2 minutes each<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes in voice quality | Voice is an effective biomarker to monitor and predict the loss of asthma control | A maximum of 9 voice sample recording session, 2 minutes each, will be carried out during the 6 months of the study |