MANAGE-AF Registry -MANAGEment of Atrial Fibrillation Outcomes Registry (MANAGE-AF)

Study Overview
=================
Brief Summary
-----------------
The purpose of this research is to learn more about the normal care of patients with a new or pre-existing diagnosis of atrial fibrillation (AF). These abnormal and irregular heartbeats place patients at increased risk of developing clots in their bloodstream that could potentially lead to stroke. Normal care is designed to help prevent this from happening and to lessen or eliminate the symptoms patients may have. There are many different types of AF as well as numerous ways in which a variety of patients are treated. The investigators are interested in gathering more information to better keep track of patient treatment patterns (trends) that may differ from physician to physician, hospital to hospital, medication to medication, patient to patient and if necessary, procedure to procedure.

Detailed Description
-----------------
The objective of this research is to establish a contemporary and simple to construct AF management registry that expands progressively over the continuum of care for each individual patient. The registry will be used to determine the course and progression of AF management in preventing thrombo-embolic events using rhythm and rate control interventions. Primary endpoints: Atrial fibrillation natural history Thrombo-embolic event Death Secondary endpoints: Bleeding Pro-arrhythmia Patient adherence Treatment complication

Official Title
-----------------
MANAGEment of Atrial Fibrillation Outcomes Registry (MANAGE-AF)

Conditions
-----------------
Atrial Fibrillation

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Diagnosis of valvular or non valvular atrial fibrillation ECG documented atrial fibrillation A. 12 lead B. Rhythm strip C. Event monitor D. Holter Monitor E. Implantable loop recorder Exclusion Criteria: Age below 18 years. Clinical evidence that death within 6 months is possible Inability to consent to the research or sign a consent form Inability to follow up at the research clinic at least annually for continuity of AF care and management

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Recurrence of Atrial fibrillation | The natural progression of the condition will be assessed per medical record review | From enrollment to 10- year study completion | 
| Thrombo-embolic event | All strokes, transient ischemic and systemic thrombo-embolic events | From enrollment to 10- year study completion | 
| Mortality | All cause death will be noted | From enrollment to 10- year study completion | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bleeding | All bleeding events events will be will be assessed throughout the duration of the study per medical record review | From enrollment to 10- year study completion | 
| Pro-arrhythmia | All pro-arrhythmic events will be documented and assessed | From enrollment to 10- year study completion | 
| Patient adherence | Events relating to subject non-compliance of medications will be documented for the duration of the study per medical record review | From enrollment to 10- year study completion | 
| Treatment complication | All adverse outcomes/events related to routine standard of care treatments will be noted and assessed for the duration of the study per medical record review | From enrollment to 10- year study completion | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
atrial arrhythmia, atrial fibrillation, stroke, bleeding, Left Atrial Appendage Occlusion