Influence of Two Different PEEP Niveaus and a Trendelenburg Positioning Manoeuvre on Subclavian Vein Diameter

Study Overview
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Brief Summary
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In 50 Patients who are undergoing a planned surgical procedure which require a central venous catheter the diameter of the subclavian vein is measured by ultrasound under 6 different conditions.

Detailed Description
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In 50 Patients who are undergoing a planned surgical procedure which require a central venous catheter the diameter of the subclavian vein is measured by ultrasound under 6 different conditions. The conditions are neutral positioning, PEEP 0 cm H2O, neutral positioning, PEEP 5cm H2O, neutral positioning, PEEP 10cm H2O, Trendelenburg positioning -20°, PEEP 0 cmH2O, Trendelenburg positioning -20°, PEEP 5 cmH2O, Trendelenburg positioning -20°, PEEP 10 cmH2O After these measurements a central venous catheter is used to measure the central venous pressure.

Official Title
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Influence of Two Different PEEP Niveaus and a Trendelenburg Positioning Manoeuvre on Subclavian Vein Diameter as a Surrogate Parameter in Punctures of Central Veins

Conditions
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Insufficiency; Cardiac, Complicating Surgery

Intervention / Treatment
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* Other: neutral positioning, PEEP 0 cm H2O
* Other: neutral positioning, PEEP 5cm H2O
* Other: neutral positioning, PEEP 10cm H2O
* Other: Trendelenburg positioning -20°, PEEP 0 cmH2O
* Other: Trendelenburg positioning -20°, PEEP 5 cmH2O
* Other: Trendelenburg positioning -20°, PEEP 10 cmH2O


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age >18 years cardiosurgery or neurosurgery written informed consent ECG: inus rhythm Exclusion Criteria: peacemaker kontraindications for PEEP pulmonary disease hemodynamically instable patients pregnancy pulmonal Hypertension ejection fraction < 35% severe valvular disease tricuspid insufficiency

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| ultrasound measurement<br>measuring subclavian vein Diameter in six Groups: neutral positioning, PEEP 0 cm H2O, neutral positioning, PEEP 5cm H2O, neutral positioning, PEEP 10cm H2O, Trendelenburg positioning -20°, PEEP 0 cmH2O, Trendelenburg positioning -20°, PEEP 5 cmH2O, Trendelenburg positioning -20°, PEEP 10 cmH2O After these measurements a central venous catheter is used to measure the central venous pressure. | Other: neutral positioning, PEEP 0 cm H2O<br>* neutral positioning, PEEP 0 cm H2O<br>Other: neutral positioning, PEEP 5cm H2O<br>* neutral positioning, PEEP 5cm H2O<br>Other: neutral positioning, PEEP 10cm H2O<br>* neutral positioning, PEEP 10cm H2O<br>Other: Trendelenburg positioning -20°, PEEP 0 cmH2O<br>* Trendelenburg positioning -20°, PEEP 0 cmH2O<br>Other: Trendelenburg positioning -20°, PEEP 5 cmH2O<br>* Trendelenburg positioning -20°, PEEP 5 cmH2O<br>Other: Trendelenburg positioning -20°, PEEP 10 cmH2O<br>* Trendelenburg positioning -20°, PEEP 10 cmH2O<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Diameter of vein | measurement of vein Diameter by ultrasound in a randomized order | only 1 day (the day of the measurement); no follow-up is required | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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ultrasound