P300 Brain Computer Interface Keyboard to Operate Assistive Technology

Study Overview
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Brief Summary
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The purpose of this research is to develop tools enable people who are paralyzed to operate technology and access computers. These tools are called brain computer interfaces (BCIs). BCIs would let a person use brain signals to operate technology.

Detailed Description
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The purpose of this research is to develop tools to help people who are paralyzed. These tools are called brain computer interfaces (BCIs). BCIs would let a person use brain signals to operate technology. The investigators want to make a BCI that can be used to operate commercially available technologies for communication, environmental control or computer access. The BCI would replace a keyboard to let people operate these technologies without moving. However, the investigators need people to test the BCI so that the investigators can see how well it can replace a keyboard. The investigators want to understand how well it can work so that the investigators can make it useful for people who are paralyzed. The investigators will ask people to use the BCI to do things like make a communication system speak or type words on a computer.

Conditions
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Healthy, Amyotrophic Lateral Sclerosis, Neuromuscular Disease, Spinal Cord Injury, Cerebral Palsy

Intervention / Treatment
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* Device: Brain Computer Interface Keyboard


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 18 or older. Able to read text on a computer screen Able to understand and remember instructions concerning participation Exclusion Criteria: Unable give informed consent. Unable to understand and follow instructions. Have abnormal tone or uncontrolled movements in the head-and-neck that would interfere with EEG recordings. Known to have photosensitive epilepsy. Open head lesions or sores

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Brain Computer Interface Keyboard<br>What effect does the environment (BCI, AT device, Computer) have on the accuracy of typing using a BCI keyboard? | Device: Brain Computer Interface Keyboard<br>* Subjects will wear an EEG cap for 1-4 hours (1-2 hours typical) per session and use the brain-computer interface to operate assistive technology. Subjects will be asked to participate in 3 sessions.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Accuracy of Typing With BCI Keyboard. | Accuracy for the sentence typed in each environment was calculated as the percentage of characters for which the result character matched the target character. The target characters were determined based on the next character needed to complete the sentence to be copied. In the case of errors, the next character was therefore a backspace to correct the error. The target characters were modified by subject comments to account for errors in selecting the next character. Once sentence was typed in each environment in each session on a separate day. From the three repeated sessions, there were therefore 9 total sentences per subject with 3 measures for each environment. These were treated as repeated measures for the analysis. | mean score from 3 sessions over 29 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Normal