Autobiographical Memory Organization in Schizophrenia

Study Overview
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Brief Summary
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The aim of the study is to investigate the temporal organization of autobiographical memory in patients with schizophrenia. Patients and control participants will be invited separately to participate in a 1hour walk in the city of Strasbourg and at the same time, to carry an automatic camera around their neck, which is called SenseCam®. Pictures obtained with SenseCam® will be later presented to the participants during the session of test. They will be asked to determine the chronological order of 12 pictures corresponding to 12 particular events of the tour. Then they will be asked to watch the complete sequence of photos from the tour and to determine the beginning and ending of the events that have occurred during the tour. According to the investigators hypotheses, patients should have difficulty to find out the correct chronological order of the photos and to determine the appropriate beginnings and endings of the events

Official Title
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Autobiographical Memory Organization in Schizophrenia

Conditions
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Schizophrenia

Intervention / Treatment
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* Other: questionary


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: for both patients and controls male or female willing to participate and who have signed up the legal document under the protection of health insurance for patients only schizophrenia or schizo-affective disorder according to the DSM-IV-TR criteria clinically stable for at least 2 months for controls only no psychiatric history Exclusion criteria: for both patients and controls current severe or unstable somatic illness neurological history (epilepsia, brain injury, brain surgery…) current substance use disorder (DSM-IV-TR) current major depressive disorder (DSM-IV-TR) mental retardation (IQ < 70) pregnancy, breast feeding current legal control for patients only treatment comprising benzodiazepines benzodiazepines intake during the last 3 weeks for controls only psychotropic intake during the last 3 weeks

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 55 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: healthy volunteers<br> | Other: questionary<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Specificity of memories recovered by using the SenseCam camera during the trial | SenseCam®(corresponding to the name of the automatic camera that participants will be asked to carry around their neck during the city-tour) | 1 month | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Cognition, Autobiographical, memoryCognitive, remediation