Web-based Psychological Intervention to Coronary Artery Heart Disease Patients

Study Overview
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Brief Summary
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The purpose of this study is to evaluate medical cost-effectiveness, reduce the psychological risk factors( including hostility, anxiety, depression, and perceived stress) in coronary artery disease (CAD) patients and enhance the regulation of the autonomic nervous system (including respiration rate, heart rate, distal blood vessel pulse, and finger temperament) through web-based cognitive -behavioral group therapy.

Detailed Description
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Cognitive-behavioral therapy (CBT) is effective in reducing the level of anger, hostility and depression present in coronary artery disease (CAD) patients.In Taiwan, Weng et al. also confirmed the eight-week group CBT program not only diminished the emotion disturbances including anger, hostility and depression of CAD, but also significantly prolonged the coagulation time, thus reducing the rate of thrombosis formation. Even though the therapeutic effect of the CBT program was valid, this program is still not accessible for some patients in need because they are not aware of it, or they are restricted by time and transportation. Internet-based therapeutic intervention can overcome the obstacles to access this program at any time and in any place. Presently, structured CBT intervention is provided through the Internet and used widely by patients with physical or psychological problems such as smoking, obesity, or headaches, but not by CAD patients. Therefore, the purpose of this research is to evaluate the effects to reduce the psychological risk factors of a web-based group CBT program in CAD patients. Follow-up assessments will be performed after 3 and 6-month durations. The investigators expect that, after an eight-week group intervention, there will be significant decrease of the psychological risk factors. Moreover, the therapeutic effects can be maintained during the three- and six-month follow-up.evaluate In addition, web-based cognitive -behavioral group therapy will significantly reduce indirect medical costs (travel time and money).

Official Title
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Development and Evaluation of a Web-based Group Cognitive-behavioral Therapy Program for Coronary Artery Heart Disease Patients

Conditions
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Coronary Artery Disease

Intervention / Treatment
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* Other: CBT


Participation Criteria
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Eligibility Criteria
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inclusion: coronary artery disease regular medication exclusion: 1.Psychiatric diseases

Ages Eligible for Study
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Minimum Age: 30 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: CAD-CBT group therapy<br>CAD receive web-based CBT group therapy | Other: CBT<br> <br> |
| Other: CAD-CBT group therapy waiting list<br>CAD waiting list will receive web-based CBT group therapy later | Other: CBT<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Significant decrease of the psychological risk factors in web-based group CBT intervention group after an eight-week group intervention | Evaluate the effects to reduce the psychological risk factors and enhance the regulation of automatic nerve system： Time point：Post-intervention, 3 months, and 6 months follow up Subjective (self report inventories), including hostility, anxiety,and perceived stress. Objective (Biofeedback devices):including blood vessel pulse, EKG, skin conductance, ect. | Time point(s) at post-group intervention, 3 months, and 6 months follow up | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Significantly reduce health care costs | Evaluate indirect medical cost-effectiveness (travel time and money) during web-based Psychological Interventions | intervention |