Cognitive Behavior Therapy for Anxiety-related Asthma in Adults.

Study Overview
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Brief Summary
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This is a study to develop a protocol on Cognitive behavior therapy (CBT) for asthma-related anxiety that in a consecutive study can be translated to internet-delivered CBT.

Detailed Description
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Asthma is one of the most common chronic diseases around the world, with a high prevalence of anxiety disorders. Cognitive behaviour therapy (CBT) has been shown to increase psychological well-being for anxiety-related asthma. Our primary aim is to develop a standardized CBT protocol for asthma-related anxiety that can be transferred to internet-delivered CBT. Ten participants will be included in a single-subject multiple baseline design. They will all receive 10-12 sessions of CBT.

Official Title
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Cognitive Behavior Therapy for Anxiety-related Asthma in Adults.

Conditions
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Asthma

Intervention / Treatment
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* Behavioral: CBT for anxiety-related asthma


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: asthma diagnosed by a physician anxiety or stress related to asthma Exclusion Criteria: severe psychiatric disorder (e.g. psychotic disorder, addiction disorder, suicidal ideation).

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Interventional Model Description: Single-subject multiple baseline design.
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: CBT for anxiety-related asthma<br>Ten to twelve weekly sessions of CBT targeting enhanced function and decreased symptoms of anxiety. | Behavioral: CBT for anxiety-related asthma<br>* The specific assignments in the intervention will be based on individual behavior analysis for each participant.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Penn State Worry Questionnaire | Change in subjective worry measured with a self-rating scale weekly during 1-3 weeks at baseline and at 10 to 12 weeks post treatment for analysis of effect. | Baseline to 12 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Anxiety Sensitivity Index-3 | Change in anxiety sensitivity measured with a self-rating scale weekly during 1-3 weeks at baseline and at 10 to 12 weeks post treatment for analysis of effect. | Baseline to 12 weeks | 
| Short Health Anxiety Inventory (SHAI) | Change in health anxiety measured with a self-rating scale weekly during 1-3 weeks at baseline and at 10 to 12 weeks post treatment for analysis of effect. | Baseline to 12 weeks | 
| Asthma Quality of Life Questionnaire | Change in asthma-related quality of life measured with a self-rating scale at pretreatment and at 10 to 12 weeks post treatment for analysis of effect. | Baseline to 12 weeks | 
| Asthma control test | Change in asthma control measured with a self-rating scale daily during weekly 1-3 weeks at baseline and at 10 to 12 weeks post treatment for analysis of effect. | Baseline to 12 weeks | 
| Catastrophizing about asthma Scale | Change in catastrophizing cognitions about asthma measured with a self-rating scale weekly during 1-3 weeks at baseline and at 10 to 12 weeks post treatment for analysis of effect. | Baseline to 12 weeks | 
| Perceived Stress Scale | Change in perceived stress measured with a self-rating scale weekly 1-3 weeks at baseline and at 10 to 12 weeks post treatment for analysis of effect. | Baseline to 12 weeks | 
| Patient Health Questionnaire | Change in depression measured with a self-rating scale at baseline and at 10 to 12 weeks post treatment for analysis of effect. | Baseline to 12 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Anxiety, Stress, Asthma