Effects of Electromagnetic Field and Noise on Resting Electroencephalogram of Health Subjects

Study Overview
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Brief Summary
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With the development of science and technology, there are more and more electromagnetic and noise factors in the working and living environment. These two factors often exist together, and their impact on people may interact. Scalp EEG is a classic nerve detection technology, which can reflect the functional state of the brain in a non-invasive and real-time manner. This project intends to use EEG technology to study the effects of electromagnetism and noise on human brain function.

Official Title
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Effects of Electromagnetic Field and Noise on Alpha Band and Functional Connections of Human Resting Electroencephalogram

Conditions
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Electroencephalography, Electromagnetic, Noise Exposure

Intervention / Treatment
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* Other: noise expose
* Other: RF expose


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Male, 18-30 years old, right-handed, with normal hearing and normal visual or corrected acuity; Exclusion Criteria: Have history of smoking, alcohol abuse, no history of neurological or psychiatric disorders (e.g., epilepsy), no relevant family history, and no recent medication use; Have history of surgery for head injury, no metal implants in the body (including braces); Sleep-wake time irregular， with sleep disturbance; Have history of noise allergy; Participate in similar psychological experiments during 2 months.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 30 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: noise(low-level) and RF(low-level)<br> | Other: noise expose<br>* simulate noise expose environments<br>Other: RF expose<br>* simulate RF expose environments<br>|
| Active Comparator: noise(high-level) and RF(low-level)<br> | Other: noise expose<br>* simulate noise expose environments<br>Other: RF expose<br>* simulate RF expose environments<br>|
| Active Comparator: noise(high-level) and RF(high-level)<br> | Other: noise expose<br>* simulate noise expose environments<br>Other: RF expose<br>* simulate RF expose environments<br>|
| Active Comparator: noise(low-level) and RF(high-level)<br> | Other: noise expose<br>* simulate noise expose environments<br>Other: RF expose<br>* simulate RF expose environments<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| alpha band power of the EEG spectral |  | Procedure (record EEG during the noise and RF expose, and then compute the alpha band power of the EEG ) | 
| theta band power/beta band power of the EEG spectral |  | Procedure (record EEG during the noise and RF expose, and then compute theta/beta of the EEG ) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Electroencephalography, Noise Exposure, electromagnetic Exposure