PRETERM DELİVERY and MYOCINE BINDING PROTEIN C LEVELs

Study Overview
=================
Brief Summary
-----------------
IT WAS AIMED TO EVALUATE IF MBPC CAN BE USED IN PREDICTION OF EARLY BIRTH. TAKING THE FIRST TRIMESTER FROM PREGNANCY WAS STORED UNTIL THE TIMING OF DELIVERY.THE PARTICIPANTS WERE SEPARATED INTO TWO GROUPS ACCORDING TO THE TIME OF BIRTH, EARLY AND TIMELY. SERUM MBPC LEVELS BETWEEN TWO GROUPS EVALUATED.

Detailed Description
-----------------
IT WAS AIMED TO EVALUATE IF MBPC CAN BE USED IN PREDICTION OF EARLY BIRTH. TAKING THE FIRST TRIMESTER FROM PREGNANCY WAS STORED UNTIL THE TIMING OF DELIVERY.THE PARTICIPANTS WERE SEPARATED INTO TWO GROUPS ACCORDING TO THE TIME OF BIRTH, EARLY AND TIMELY. SERUM MBPC LEVELS BETWEEN TWO GROUPS EVALUATED.A TOTAL OF 90 WOMEN WERE PLANNED TO INCLUDE 45 STUDY 45 CONTROL GROUP IN THE STUDY.

Official Title
-----------------
Can First Trimester Serum Myocine Binding Protein c Level Predict Preterm Birth

Conditions
-----------------
Preterm

Intervention / Treatment
-----------------
* Diagnostic Test: level of myosin binding protein c in serum


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: being pregnant in the first trimester be between 18-40 years old Exclusion Criteria: no history of preterm birth being pregnant with assisted reproductive techniques having a multiple pregnancy have cervical insufficiency

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 40 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| women who gave birth prematurely<br>women who had serum taken in the first trimester and gave birth earlier than 37 weeks according to the time of delivery | Diagnostic Test: level of myosin binding protein c in serum<br>* Serum samples will be taken from the participants in the first trimester, transferred to eppendorf tubes after appropriate procedures, and stored at -80 degrees until the time of deliveryParticipants will be divided into two groups according to the timing of birthThe first group is those who gave birth earlier than 37 weeks those who gave birth on time in the other group The mbpc levels will be looked at and compared.<br>|
| those who gave birth on time<br>women who have had serum taken in the first trimester, stored and delivered on time | Diagnostic Test: level of myosin binding protein c in serum<br>* Serum samples will be taken from the participants in the first trimester, transferred to eppendorf tubes after appropriate procedures, and stored at -80 degrees until the time of deliveryParticipants will be divided into two groups according to the timing of birthThe first group is those who gave birth earlier than 37 weeks those who gave birth on time in the other group The mbpc levels will be looked at and compared.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| detection of prediction value of serum mbpc levels in preterm delivery | identifying prediction value of first trmester serum mbpc levels by comparing by serum levels of mbpc in groups | 10 mounths | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
PRETERM DELİVERY, MBPC,