Right Lateral Positioning and Its Effect on Induction of General Anesthesia for Children

Study Overview
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Brief Summary
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The quality of induction with sevoflurane, along with its ability to generate optimal conditions for Laryngeal Mask Airway (LMA) insertion without supplemental opioids or muscle relaxants, has also been well documented. An ideal inhalation induction technique besides being rapid and comfortable for the patient should be economical. To achieve rapidity, use of vital capacity breaths with 8% sevoflurane is a more popular method of induction compared with the conventional incremental induction.

Detailed Description
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100 pediatric patients (age range, 1 to 8 years) scheduled for lower abdominal surgery under anesthesia will be included. All children in both groups will be premedicated with midazolam, 0.5 mg/kg orally, about 30 minutes before the induction of anesthesia. A parent or guardian accompanied the child into the operating room to allow the child to remain calm and cooperative for inhalation induction. Before induction, pulse oximetry and electrocardiogram monitoring will be attached. For each group, inhalation induction was initiated using a face mask using tidal volume and vital capacity breathing in high sevoflurane concentration (8%).

Official Title
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Right Lateral Positioning and Its Effect on Induction of General Anesthesia for Children

Conditions
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Anesthesia

Intervention / Treatment
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* Procedure: supine position
* Procedure: Right lateral position


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Children aged 1 years to 8 years Children with ASA class I/II and their willingness to participate in the study Exclusion Criteria: Known seizure disorder Craniofacial abnormalities/difficult airway Cardiopulmonary or neuromuscular defects Hepatic or renal insufficiency Expected difficult intravenous (IV) cannulation (eg, dark complexion, obese) Catching colds during the past four weeks

Ages Eligible for Study
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Minimum Age: 1 Year
Maximum Age: 8 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Supine group<br>Anesthesia induction with sevoflurane for the patient while he is in supine position. | Procedure: supine position<br>* Anesthesia induction with sevoflurane for the patient while he is in supine position.<br>|
| Active Comparator: Right lateral group<br>Anesthesia induction with sevoflurane for the patient while he is in right lateral position position. | Procedure: Right lateral position<br>* Anesthesia induction with sevoflurane for the patient while he is in right lateral position.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Induction time | The time from starting induction of anesthesia until successful insertion of the LMA (seconds) | an expected 30 minutes | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| LMA trials (Number of patients in each group required insertion of an LMA more than once) | Number of patients in each group required insertion of an LMA more than once | an expected 60 minutes | 
| Blood pressure | Systolic, diastolic and mean blood pressure mm Hg | Duration of from starting induction of anesthesia till LMA an expected average of 60 minutes | 
| Heart rate | Heart rate beats per minute | Duration of from starting induction of anesthesia till LMA an expected average of 60 minutes | 
| Oxygen saturation | Oxygen saturation % | Duration of from starting induction of anesthesia till LMA an expected average of 60 minutes | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Right lateral, Induction, Children, Anesthesia