Effect of CV4 and Rib Raising Techniques on Autonomic Balance

Study Overview
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Brief Summary
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Background. Heart rate variability (HRV) and skin conductance (SC) highlight autonomic activity and the balance of autonomic nervous system (ANS) which regulates involuntary physiological functions. The modulation of ANS tonic activity is a target of osteopathic manipulative treatment (OMT). The main aim of the present study was to verify whether CV4 and RR osteopathic techniques influence ANS activity. Trial design. A randomized-controlled clinical trial was performed from June 2010 to January 2011. Methods. 32 healthy adults were selected. At enrollment, all healthy subjects were randomized in three groups: CV4 group (CV4 technique), Rib Raising group (RR technique), and Placebo group (PL technique). HRV and SC was recorded during the session respectively with heart rate monitor Polar S810i and with Onda Scanner Domiana (OSD-Microsale model). All data analysis was performed using SPSS statistical software and the significance level set at p≤0.05.

Official Title
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Variations of Heart Rate Variability and Skin Conductance Reveal the Influence of CV4 and Rib Raising Osteopathic Techniques on the Autonomic Nervous System: a Randomized Controlled Trial

Conditions
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Autonomic Nervous System Disease, Osteopathy

Intervention / Treatment
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* Other: CV4 technique
* Other: RR technique
* Other: Placebo treatment


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: healthy subjects between 18-65 years old both gender Exclusion Criteria: BMI ≥ 30 pregnancy menstrual flow during the session chronic pain chronic drug treatment presence of skin, cardiovascular, psychiatric and neurological diseases medical history of surgical interventions OMT in the previous 3 months

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: CV4 group<br>CV4 technique | Other: CV4 technique<br> <br> |
| Experimental: RR group<br>Rib Raising technique | Other: RR technique<br> <br> |
| Placebo Comparator: Placebo group<br>Light touch | Other: Placebo treatment<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Heart Rate Variability | HRV was measured using a heart rate monitor Polar S810i frequency meter | 1200 seconds | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Skin Conductance | SC was measured using a Onda Scanner Domiana (OSD-Microsale model). | 1200 seconds | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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heart rate variability, autonomic nervous system, osteopathic manipulative treatment, skin conductance