Topical Therapy With Cooling Effect in Dry Itchy Skin

Study Overview
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Brief Summary
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Dry skin is a physiological condition and is characterized in contrast to greasy skin by roughness, desquamation and lack of brightness of the skin surface. Subjectively, feelings of tension, burning and itching can occur. The skin reacts more intensive on external and physical noxae. Dry skin is caused by a lack of moisture. This is most common during the winter months, when heating systems dry the air. Bathing with hot water, spending extended periods of time in the hot sun, and the skin's natural aging process also remove moisture and oils from the skin. It is diagnosed through clinical observation. People suffering from dry skin often desire to improve this condition for optical cosmetic reasons and due to the occasional feeling of tension. The aim of this investigation is to observe the improvement (or not) of dry itchy skin by a lotion containing a cooling compound

Detailed Description
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The patient use the lotion twice daily for a four-week period. Additionally, the patient receives a documentation sheets to note several parameters. In a sensory assessment, product specific parameter such as spreadability, permeability, lubricating, smell of lotion and cosmetic acceptance during the treatment will be assessed (at the beginning, after 2 weeks, after 4 weeks, 2 weeks after stopping treatment). Before and after skin care measurement, the skin surface will be investigated by d-squames and corneometer. After four weeks the skin care measurement will be terminated and the patient can continue with a treatment of his choice. A monitoring of at least 70 patients is intended.

Official Title
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kühlender Effekt Der Eucerin pH5 Lotion Und Der Eucerin pH5 Lotion Mit Cooling Compound Bei Trockener, Juckender Haut

Conditions
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Compensate the Roughness of the Skin, Compensate the Sensory Symptoms

Intervention / Treatment
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* Device: cooling compound (ph5 Eucerin)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients age: over 18 years itch over VAS 3 Exclusion Criteria: pregnancy, lactating women drug abuse active psychosomatic and psychiatric disease active cancer. topical application of tacrolimus, pimecrolimus, corticosteroids or capsaicin two weeks before study start intake of antihistamines, corticosteroids, cyclosporine A and other immunosuppressants, naltrexone, UV-therapy two weeks before study start participation in any other research study during the previous 4 weeks.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: 1<br>ph5 Eucerin Lotion with cooling compound | Device: cooling compound (ph5 Eucerin)<br>* application twice daily to the skin<br>* Other names: ph5 Eucerin;|
| Placebo Comparator: 2<br>ph5 Eucerin Lotion | Device: cooling compound (ph5 Eucerin)<br>* application twice daily to the skin<br>* Other names: ph5 Eucerin;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Compensate the roughness of the skin Compensate sensory symptoms |  | 4 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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dry skin, cooling, itch