linjc16/ctgov huggingface dataset:
Transmyocardial Laser Revascularization and Cardiovascular Magnetic Resonance Imaging

Study Overview
=================
Brief Summary
-----------------
The primary goal of this study is to better understand how Transmyocardial Laser Revascularization (TMR) affects the functioning of the heart and, in turn, relieves angina in individuals with coronary heart disease using Magnetic Resonance (MR) images and Computed Tomography (CT) images in some patients.

Official Title
-----------------
Effect of Transmyocardial Laser Revascularization on Myocardial Perfusion and Left Ventricular Structure by Cardiovascular Magnetic Resonance Imaging and Dynamic Volumetric Computed Tomography

Conditions
-----------------
Angina, Chest Pain

Intervention / Treatment
-----------------
* Other: Cardiac MRI


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Male or female 18 years of age or over Patients with medically refractory, severe, class III or IV angina based on the Canadian Cardiovascular Society angina scale as determined by a physician Ejection fraction 25% or greater Patients with significant ischemia in the myocardium and who are NOT candidates for treatment by direct coronary revascularization methods (i.e., CABG or PCI) Ability and willingness to consent and Authorization for use of PHI Exclusion Criteria: Patient cannot undergo a surgical procedure or general anesthesia Patient not eligible for CMR study Severe unstable angina Q-wave MI within 3 weeks prior to TMR NQWMI within 2 weeks prior to TMR Decompensated heart failure (class III/IV) at the time of procedure Known increased bleeding risk Implanted pacemaker or defibrillator Clinically unstable arrhythmia Not able or willing to adhere to the study tests and procedures Inability or unwillingness to consent and Authorization for use of PHI

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: All Patients<br>All patients undergo the same study procedures | Other: Cardiac MRI<br>* Cardiac MRI within 30 days prior to TMR procedure and 6 months after TMR procedure.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of coronary arteries with blood flow defects evaluated by magnetic resonance imaging (MRI) or computed tomography (CT) |  | 6 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Cardiac, Angina, Chest pain
Anatomical Femoral Stem in Total Hip Arthroplasty

Study Overview
=================
Brief Summary
-----------------
A study that detect the femoral anteversion after total hip arthroplasty using short anatomical femoral stem compared to the contrast side

Official Title
-----------------
Short Term Results of Short Anatomical Femoral Stem in Total Hip Arthroplasty - Prospective Study

Conditions
-----------------
Patient Compliance, Patient Satisfaction

Intervention / Treatment
-----------------
* Device: Short anatomical femoral stem in THR


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: age 18-90 patients who had THR as an elective surgery patients who had THR with short femoral anatomical stem Exclusion Criteria: severe osteoporosis with Dorr C classification s/p bilateral hip arthroplasty non-complaint patients revision surgery

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 90 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Group 1<br>Patients after total hip arthroplasty with short femoral stem | Device: Short anatomical femoral stem in THR<br>* Patients with osteoarthritis after total hip arthroplasty<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Femoral anteversion | comparing femoral anteversion after THR using CT scan | Post-Operatively, through study completion, an average of 2 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Harris Hip Score | The HHS is a physician-completed instrument that consists of subscales for pain severity (1 item, 0-44 points), function (7 items, 0-47 points), absence of deformity (1 item, 0-4 points), and range of motion (2 items, 0-5 points). Where a score < 70 indicating a poor result and those of 90-100 indicating an excellent result | 6 weeks, 3 month, 6 month post-operative |
A Randomized Controlled Study of Prolonging the Time of Progesterone Supplementation to Improve the Pregnancy Outcome of Single Day 6 Blastocyst Transfer of Freeze-thaw Cycle

Study Overview
=================
Brief Summary
-----------------
This is a single-center, prospective, randomized controlled study. Patients with single blastocyst transfer in the freeze-thaw cycle, aged from 20 to 38 years, with less than three transfers, and with HRT-cycle single D6 blastocyst transfer in the current cycle were enrolled as the study participants. They were randomized into two groups using an Excel table, and the efficacy was evaluated in a blinded manner by a third party who was unaware of the grouping; the data summary phase was performed by blinded statistical analysis with triple separation of the investigator, operator, and statistician.

Official Title
-----------------
A Randomized Controlled Study of Prolonging the Time of Progesterone Supplementation to Improve the Pregnancy Outcome of Single Day 6 Blastocyst Transfer of Freeze-thaw Cycle

Conditions
-----------------
Infertility

Intervention / Treatment
-----------------
* Drug: progesterone
* Drug: progesterone


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Aged 20 to 38 years. Less than three transfers. Undergoing HRT freeze-thaw cycle single blastocyst transfer in the current cycle. Having consented to participate in this study and signed the informed consent form. Exclusion Criteria: Chromosomal abnormality in either the patient or their partner Contraindications to hormone replacement therapy. Patients with intramural myoma affecting the morphology of the uterine cavity, severe adenomyosis, endometriosis, congenital uterine anomalies, endometrial tuberculosis, intrauterine adhesion and other diseases significantly affecting embryonic implantation. Currently participating in another clinical study.

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 38 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Progesterone + 7<br>the transfer of day 6 blastocyst on the 7th day of progesterone supplementation | Drug: progesterone<br>* the transfer of day 6 blastocyst on the 7th day of progesterone supplementation<br>|
| Active Comparator: Progesterone + 6<br>the transfer of day 6 blastocysts on the 6th day of progesterone supplementation | Drug: progesterone<br>* the transfer of day 6 blastocyst on the 6th day of progesterone supplementation<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Embryo implantation rate |  | 30 days after embryo transplantation |
Salivary C- Reactive Protein, Mean Platelet Volume and Neutrophil Lymphocyte Ratio as Diagnostic Markers for Neonatal Sepsis

Study Overview
=================
Brief Summary
-----------------
To evaluate reliability of salivary C-reactive protein ,mean platelet volume , neutrophil -lymphocyte ratio , and platelet lymphocyte ratio in diagnosis of neonatal sepsis

Official Title
-----------------
Salivary C-reactive Protein,Mean Platelet Volume and Neutrophil Lymphocyte Ratio as Diagnostic Markers for Neonatal Sepsis

Conditions
-----------------
Neonatal Sepsis

Intervention / Treatment
-----------------
* Diagnostic Test: Salivary CRP


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: - Full term neonates of both genders from birth to the 28th day of life diagnosed with sepsis by history, clinical findings, laboratory findings, and blood culture. The clinical findings included the presence of three or more of the following: (1) temperature instability (hypothermia, hyperthermia) . (2) respiratory alterations (grunting, intercostal retractions, apnea, tachypnea, cyanosis) . (3) cardiovascular alterations (bradycardia, tachycardia, poor perfusion, hypotension) . (4) neurologic alterations (hypotonia, lethargy, seizures) (5) gastrointestinal alterations (feeding intolerance, abdominal distension). CRP values >10 mg/L were considered to be positive. Exclusion Criteria: - Preterm neonates . Neonates with CNS malformations, metabolic disorders, chromosomal abnormalities, intrauterine growth restriction, or birth asphyxia were excluded from the study

Ages Eligible for Study
-----------------
Minimum Age: 1 Day
Maximum Age: 28 Days

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Case group of fullterm neonates with neonatal sepsis<br> | Diagnostic Test: Salivary CRP<br>* Salivary C reactive protein in neonatal sepsis<br>|
| Healthy fullterm neonates<br> | Diagnostic Test: Salivary CRP<br>* Salivary C reactive protein in neonatal sepsis<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Salivary c reactive protein in neonatal sepsis | Salivary C reactive protein of value as non invasive procedure in diagnosis of neonatal sepsis | 28 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mean platelet volume | Asses the validity of Mean Platlet Volume as marker of neonatal sepsis which is equal about ( 9 - 11.4 ) in septic group and about ( 7.5 - 8.5 ) in control group | 28 days |
A Randomized Controlled Double Blinding Study of Intradermal Acupuncture Treatment on Obesity

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to determine whether intradermal acupuncture is effective and safe in the treatment of obesity.

Detailed Description
-----------------
Recently the Studies of auricular acupuncture or Common Acupuncture on obesity have been conducted. Saam acupuncture, the Korean unique acupuncture, is famous with its high efficacy but not established by the scientific way yet. Thus, we tried a double-blind study on the effect of sa-am acupuncture on obesity using intradermal acupuncture.

Official Title
-----------------
Korea Institute of Oriental Medicine

Conditions
-----------------
Obesity

Intervention / Treatment
-----------------
* Device: Intradermal Acupuncture Treatment


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: BMI>25, regular menstruation, volunteer Exclusion Criteria: symptomatic obesity, acupuncture treatment within 3 months, >120kg, pregnancy or breast-feeding, hemophilia, dementia, mental illness, arrhythmia, liver cirrhosis, renal failure, pace maker, diabete mellitus, tuberculosis, steroid taker,

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 50 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Intervention/Treatment |
| --- |
|Device: Intradermal Acupuncture Treatment|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bio-body impedance methods |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cholesterol, Triglycerides, HDL LDL cholesterol |  |  |
Using Hypnosis to Help Children Undergoing a Difficult Medical Procedure

Study Overview
=================
Brief Summary
-----------------
This study examined whether a hypnosis intervention, compared to standard care, could help reduce distress and pain for children undergoing an invasive medical procedure.

Conditions
-----------------
Voiding Cystourethrogram (VCUG)

Intervention / Treatment
-----------------
* Behavioral: hypnosis


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: The child: (1) was scheduled for an upcoming VCUG ; (2) must have undergone at least one previous VCUG; (3) was at least 4 years of age at the time of the previous VCUG; (4) experienced distress during the previous VCUG; and (5) both child and participating parent were English speaking. Exclusion Criteria: Not meeting any of the above criteria.

Ages Eligible for Study
-----------------
Minimum Age: 5 Years
Maximum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Design Details

Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: hypnosis|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
In-vitro and In-vivo Comparative Evaluation of Rotary Fanta and Zunba Files in Root Canal Preparation of Infected Primary Molars

Study Overview
=================
Brief Summary
-----------------
Adequate shaping and cleaning, followed by a good coronal seal, are prerequisites for a favorable outcome. The goal of root canal preparation is to create optimized canal geometry to allow effective irrigation and obturation with preservation of the original canal morphology. The aim of current study is to evaluate the effectiveness of Fanta and Zunba rotatory instruments in cleaning of infected root canal of primary molars to those instrumented with manual K-files.

Official Title
-----------------
In-vitro and In-vivo Comparative Evaluation of Rotary Fanta and Zunba Files in Root Canal Preparation of Infected Primary Molars

Conditions
-----------------
Root Canal Preparation of Infected Primary Molars

Intervention / Treatment
-----------------
* Procedure: root canal preparation


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Class I or II according to American Society of Anesthesiologists (ASA) Necrotic pulp tissues which may be asymptomatic or manifested with dull ache pain Pathological tooth mobility Percussion sensitivity Swelling close to involved tooth accompanied with or without fistula The extension of radiolucency at the furcation area did not exceed half of the space between the furcation and the permanent successor No internal root resorption External root resorption (Physiologic or pathologic) limited to apical third and with at least two-third root intact Exclusion Criteria: Uncooperativeness of child and/or parents or caregiver's behavior. Unrestorable tooth. Presence of calcific metamorphosis inside root canals.

Ages Eligible for Study
-----------------
Minimum Age: 4 Years
Maximum Age: 7 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Fanta and Zunba rotatory files<br>Fanta and Zunba rotatory files | Procedure: root canal preparation<br>* root canal preparation<br>|
| Active Comparator: manual K-files<br>manual K-files | Procedure: root canal preparation<br>* root canal preparation<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| clinical success rate | Presence or abscnce (+/-) of pain, mobility and/or fistulous tract | 12 month | 
| radiographic success rate | Presence or abscnce (+/-) of periapical rdiolucency | 12 month |
Treatment for Women With Post-Traumatic Stress Disorder Related to Childhood Abuse

Study Overview
=================
Brief Summary
-----------------
This study will compare one- and two-component treatments in women with post-traumatic stress disorder (PTSD).

Detailed Description
-----------------
PTSD is a debilitating and often chronic anxiety disorder with serious psychiatric comorbidity. The most common trauma associated with PTSD among women is childhood abuse. PTSD related to childhood abuse may cause problems with emotion regulation and interpersonal functioning. This study will address three domains of PTSD related to childhood abuse: emotion management problems, interpersonal problems, and PTSD symptoms. Participants in this study will be randomly assigned to 16 sessions of one of three treatments: Skills Training for Affective and Interpersonal Regulation (STAIR), which focuses on helping individuals strengthen and build skills in managing feelings and improving interpersonal relationships; Modified Prolonged Exposure (MPE), which focuses on developing narratives of abuse history and completing an emotional processing of the trauma in a safe environment; and a combination of STAIR and MPE. Dropout rates and adverse effects will be measured.

Official Title
-----------------
Skills Training, Exposure, and Their Combination in Childhood Abuse PTSD

Conditions
-----------------
Stress Disorders, Post-Traumatic

Intervention / Treatment
-----------------
* Behavioral: Psychotherapy treatment


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: DSM-IV criteria for Post-Traumatic Stress Disorder related to childhood physical and/or sexual abuse by a care-giver At least one clear memory of the abuse Willing to have all assessments tape recorded and sessions video taped Willing to maintain any concurrent treatments for the duration of the study Exclusion Criteria: Bipolar Disorder Eating Disorder Borderline Personality Disorder Active substance abuse or dependence Living with the abuser Self mutilation Pregnancy

Ages Eligible for Study
-----------------
Minimum Age: 22 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: study arm<br> | Behavioral: Psychotherapy treatment<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| outcome |  | within study timeframe |
Modified Technique in Sacrospinous Fixation for Treatment of Apical Genital Prolapse

Study Overview
=================
Brief Summary
-----------------
Pelvic organ prolapse is one of the most common benign gynecological disorders and affects approximately 40% of women over 50 years of age. The causes of utero vaginal prolapse are pregnancy, labor, obesity, increased intra-abdominal pressure, and weak pelvic floor structures

Official Title
-----------------
A Modified Technique in Sacrospinous Fixation Using Posterior Vaginal Wall Flap for Treatment of Apical Genital Prolapse

Conditions
-----------------
Genital Prolapse

Intervention / Treatment
-----------------
* Procedure: sacrospinous fixation Using Posterior Vaginal wall flap


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 1- Symptomatic Stage II , III and Stage IV Apical Prolapse (diagnosed by pop Q test ) . Exclusion Criteria: Patients with medical disorders that may interfere with surgical interventions ( Like severe chest and heart diseases , renal and liver cell failure , bleeding tendency ) . Patients with urinary incontinence ( excluded by history , examination & Urodynamics)
Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| study group<br>patients with symptomatic Stage II , III and Stage IV Apical Prolapse (diagnosed by pop Q test) | Procedure: sacrospinous fixation Using Posterior Vaginal wall flap<br>* Identification of the sacro spinous ligament. Insertion of the sacrospinous stitch. Using a long - handled needle holder, a J - shaped Ethibond suture is placed 2 - 3 cm medial to the right ischial spine. Using posterior vaginal wall flap (rectangular flap )will be incised and retracted Superior to the right , the stitch of sacro spinous ligament will be attached to the flap not the vault after adjusting its size , then the sit . The stitch should be placed through and not around the ligament. The application of firm traction to the suture length will test the correctness of its placement. A second suture is inserted for additional support. We may do it directly or by using an alternative surgical instruments for placement of the suture include the knee scorpion. Per rectum examination should be undertaken to check for misplaced sutures. Attachment of the sutures to the vaginal flap . The two sutures are then secured to the upper posterior aspect of the vaginal flap ,<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The difference of quality life score | this will be assessed before and after the surgery using | 6 months |