Prognosis Factors for the Treatment of Pectus Carinatum With a Dynamic Compression System

Study Overview
=================
Brief Summary
-----------------
Pectus carinatum is a deformation of the thoracic wall causing an aesthetic prejudice. Since 2011, our team uses a dynamic compression system to treat this deformation. It is a harness that the patient wears all day long for an average duration of 1 year, and that remodels the chest by exerting a moderate pressure on it. The local cohort is one of the largest in the world. The few previous publications have shown the validity of this method, but the prognosis factors for success of this innovative treatment are not yet identified.

Detailed Description
-----------------
The principal insvestigator hypothesizes that the success or failure of the treatment depends on several parameters assessable before treatment, such as the patient's age, gender, initial correction pressure, symmetry or not of the deformation.

Official Title
-----------------
Prognosis Factors for the Treatment of Pectus Carinatum With a Dynamic Compression System

Conditions
-----------------
Pectus Carinatum

Intervention / Treatment
-----------------
* Other: dynamic compression system


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patient who received proper information about the study. Patient with clinically diagnosed pectus carinatum. Treated at Saint-Etienne University Hospital using a dynamic compression system. Between October 2011 and January 2020 for the retrospective part, then between January 2020 and January 2022 for the validation cohort. With more than 6 months of follow-up since the beginning of the treatment. Exclusion Criteria: -

Ages Eligible for Study
-----------------
Minimum Age: 6 Years
Maximum Age: 40 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Retrospective cohort<br>340 to 400 patients | Other: dynamic compression system<br>* It is a harness that the patient wears all day long for an average duration of 1 year, and that remodels the chest by exerting a moderate pressure on it<br>|
| Validation cohort<br>120 patients | Other: dynamic compression system<br>* It is a harness that the patient wears all day long for an average duration of 1 year, and that remodels the chest by exerting a moderate pressure on it<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Decrease of the deformation of more than 50% (measured in mm) after 6 months of treatment | Dynamic compression system | After 6 months of treatment | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Failure of treatment assessed by the patient, ie if the patients considers the treatment to have failed, if he choose to underwent surgery afterwards, or if he considered the pectus carinatum to have relapsed | Dynamic compression system | After the end of treatment (6 months to 2 years) | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Pectus Carinatum, Dynamic compression system