Comparison of Quality of Life Between Patients Underwent Transoral Endoscopic Thyroid Surgery and Conventional Surgery

Study Overview
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Brief Summary
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The purpose of this study is to determine the quality of life of transoral endoscopic thyroidectomy compare with open thyroidectomy, Furthermore, postoperative complication will be assessed, also.

Detailed Description
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Regarding type of surgery, doctor will just advice about risk and benefit of any type of surgery. And then patient will select by himself. Patients are not assigned to endoscopic or conventional group. This study start to enrolled patients after surgery. And the quality of life will be observed at 2, 6 and 12 weeks, respectively.

Official Title
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Comparison of Quality of Life Between Patients Underwent Transoral Endoscopic Thyroid Surgery and Conventional Surgery

Conditions
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Quality of Life, Transoral Endoscopic Thyroidectomy, Conventional Thyroidectomy

Intervention / Treatment
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* Procedure: Transoral endoscopic thyroidectomy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patient who underwent thyroid lobectomy for benign thyroid nodule less or equal 5 cm Exclusion Criteria: previous neck surgery suspected thyroid carcinoma patient who failure endoscopic thyroidectomy and change to conventional surgery

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Transoral endoscopic thyroidectomy<br>Patient who fit with the eligible criteria and choose endoscopic thyroidectomy by himself. | Procedure: Transoral endoscopic thyroidectomy<br>* This procedure will remove thyroid lobe through oral vestibule. Aim to avoid scar at anterior neck.<br>|
| Conventional thyroidectomy<br>Patient who fit with the eligible criteria and choose conventional thyroidectomy by himself. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in quality of life after surgery | Quality of life will assessed by Short form health survey 36 and specific questionnaire for thyroidectomy. These questionnaires will assess at 2,6 and 12 weeks after surgery. The quality of life results (6 and 12 weeks) will be observed that change from 2 weeks after surgery. Furthermore, investigators will compare score of Short form health survey 36 and specific quality of life questionnaire for thyroidectomy between endoscopic and open technique at 2,6,12 week after surgery, also. | 2,6,12 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative complication | The complications will assess at 2,6, and 12 week after surgery. | 2,6, and 12 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Endoscopic surgery, Thyroidectomy, Quality of life