Virtual Reality-based Rehabilitation

Study Overview
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Brief Summary
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Vertigo / dizziness, imbalance and other symptoms related to vestibular pathology have a life prevalence of 7.4%. Peripheral and unilateral vestibulopathy are among the most common types, and in some patients the symptoms become chronic and disabling, which makes it difficult for them to lead a normal life and has a significant socio-economic impact. In recent years, the effect of vestibular rehabilitation with virtual reality has been studied and positive results have been obtained when compared with traditional rehabilitation, but despite rehabilitation there is patients who are still chronic, and the reasons for this prognostic variability are still unknown and require further treatment. Virtual reality-based stimulation can play a significant role as an adjunct to conventional vestibular rehabilitation, improving its effectiveness.

Official Title
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Realitat Virtual Com a Tractament Coadjuvant en rehabilitació Vestibular

Conditions
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Patients With Unilateral Peripheral Vestibular Deficits

Intervention / Treatment
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* Behavioral: Virtual Reality-based Rehabilitation
* Behavioral: Conventional Therapy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Unilateral vestibular deficit Vestibular neuritis Sudden hearing loss with vestibular involvement Labyrinthitis Ménière's disease Vestibular Shwannoma Benign paroxysmal positional vertigo Vestibular symptoms (vertigo, dizziness, imbalance, gait instability, kinosis and / or oscillopsy) chronic (more than 6 weeks of evolution) Over 18 years old Exclusion Criteria: Failure to meet some of the inclusion criteria Neurological, traumatological, rheumatological, ophthalmological or systemic pathology that may interfere with the balance Inability to understand participation in the study Non-acceptance to participate in the study

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Virtual reality based therapy<br> | Behavioral: Virtual Reality-based Rehabilitation<br>* VR-based eye stabilization exercises and balance exercises<br>|
| Active Comparator: Conventional Therapy<br> | Behavioral: Conventional Therapy<br>* Conventional rehabilitation therapy based on eye stabilization exercises and balance exercises<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change pre-post treatment in the Dizziness handicap inventory (DHI) (0-100) | Change within subjects from baseline to the end of week 4 | 4 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change pre-post treatment in Posturography (Wii+software RombergLab) | Change within subjects from baseline to the end of week 4 | 4 weeks | 
| Change pre-post treatment in Test up and go (TUG) | Change within subjects from baseline to the end of week 4 | 4 weeks | 
| Change pre-post treatment in Berg Scale (0-56) | Change within subjects from baseline to the end of week 4 | 4 weeks | 
| Change pre-post treatment in Tinneti Test (1-28) | Change within subjects from baseline to the end of week 4 | 4 weeks | 
| Change pre-post treatment in Simulator Sickness Questionnaire (SSQ) (0-14) | Change within subjects from baseline to the end of week 4 | 4 weeks | 
| Change pre-post treatment in the Video-head impulse test (vHIT) | Change within subjects from baseline to the end of week 4 | 4 weeks | 
| Change pre-post treatment in the Barthel Index (0-100) | Change within subjects from baseline to the end of week 4 | 4 weeks | 
| Change pre-post treatment in the SF 12 Test (0-100) | Change within subjects from baseline to the end of week 4 | 4 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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vestibular, unilateral vestibular, virtual reality, rehabilitation