Exercise for Preventing the Metabolic Syndrome in Latinoamerican Amerindians

Study Overview
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Brief Summary
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Despite exercise training decrease blood fasting glicaemy in 'average' terms, there is a wide inter-individual variability after exercise training explored mainly in adults but not in adults with prediabetes comorbidities. Thus, is yet unknown the effects and influence of the concurrent training (CT) eliciting responders (R) and non-responders (NR) cases (i.e., percentage of subjects who experienced a non-change/worsened response after training in some metabolic outcomes).

Official Title
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Similar Improvements in Cardiometabolic Risk Factors for Preventing the Metabolic Syndrome in Latinoamerican Amerindians After 12-weeks of Concurrent Training

Conditions
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Obesity, Cardiovascular Risk Factor, Physical Activity

Intervention / Treatment
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* Behavioral: Concurrent training (CT)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Written informed consent Interested in improving health and fitness Exclusion Criteria: Cardiovascular contraindications to exercise History of stroke, asthma or chronic obstructive pulmonary disease, muscle-skeletal disorders Smoking A compliance rate to the exercise program ≥ 70% was required for the participants in the intervention group to be included in the statistical analyses.

Ages Eligible for Study
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Minimum Age: 30 Years
Maximum Age: 59 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Behavioral
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: Control group<br>No-exercise | |
| Experimental: Endurance training plus resistant training<br>Concurrent training | Behavioral: Concurrent training (CT)<br>* The core part of each session included resistance training (RT) followed by aerobic training exercises (for 50 and 30 minutes, respectively) and was preceded and followed by a 5-minute warm-up and cool-down with callisthenic movements.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Fasting glucose | Change from Baseline in fasting glucose | Baseline and 20-weeks immediately after the interventions ends | 
| Total cholesterol | Change from baseline in Total cholesterol | Baseline and 20-weeks immediately after the interventions ends | 
| Blood pressure | Change from baseline in Blood pressure | Baseline and 20-weeks immediately after the interventions ends | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Body mass | Change from Baseline in body mass | Baseline and 20-weeks immediately after the interventions ends | 
| Waist circumference | Change from Baseline in waist circumference | Baseline and 20-weeks immediately after the interventions ends | 
| Fat mass | Change from Baseline in fat mass | Baseline and 20-weeks immediately after the interventions ends | 
| Lean mass | Change from Baseline in lean mass | Baseline and 20-weeks immediately after the interventions ends | 
| Heart rate at rest | Change from Baseline in heart rate at rest | Baseline and 20-weeks immediately after the interventions ends | 
| Six minutes walking test | Change from Baseline in six minutes walking test | Baseline and 20-weeks immediately after the interventions ends |