Impact of Sarcopenia Index on Postoperative Pulmonary Complication in Elderly Patients Undergoing OPCAB

Study Overview
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Brief Summary
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Retrospective data collection. The aim of this study is to determine the effect of preoperative sarcopenia index on postoperative pulmonary complications in elderly patients undergoing off-pump coronary artery bypass graft surgery.

Official Title
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Impact of Sarcopenia Index on Postoperative Pulmonary Complication in Elderly Patients Undergoing OPCAB: a Retrospective Study

Conditions
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Coronary Artery Occlusive Disease

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients who were 65 years of age or older at the time of surgery(off-pump coronary artery bypass graft surgery) serum cystatin C and creatinine test results were valid within one week before surgery Exclusion Criteria: Patients with chronic renal failure (estimated glomerular filtration rate less than 60) Patients with acute kidney injury Patients with respiratory tract infection within 1 month before surgery

Ages Eligible for Study
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Minimum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| postoperative pulmonary complications : pneumonia | CXR with at least one of the following: infiltrate, consolidation, cavitation;plus at least one of the following: fever >38 °C with no other cause, white cell count <4 or>12*109 litre-1, >70 yr of age with altered mental status with no other cause;-plus at least two of the following: new purulent/ changed sputum, increased secretions/suctioning, new/worse cough/dyspnoea/tachypnoea, rales/ bronchial breath sounds, worsening gas exchange. | During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days. | 
| postoperative pulmonary complications : prolonged ventilation | Indicate whether the patient had prolonged post-operative pulmonary ventilation > 24.0 hours. The hours of postoperative ventilation time include OR exit until extubation, plus any additional hours following reintubation. | During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days. | 
| postoperative pulmonary complications : reintubation | Indicate whether the patient was intubated for the first time after leaving the OR from the initial procedure, or re-intubated during the hospital stay after the initial extubation. | During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| postoperative complications : Renal failure | Indicate whether the patient had acute renal failure or worsening renal function resulting in ONE OR BOTH of the following: 1. Increase in serum creatinine level 3.0 x greater than baseline, or serum creatinine level ≥4 mg/dL , Acute rise must be at least 0.5 mg/dl 2. A new requirement for dialysis postoperatively. | During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days. | 
| postoperative complications : Delirium | Indicate whether the patient experienced postoperative delirium from OR Exit to ICU discharge. | During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days. | 
| postoperative complications : Reoperation due to bleeding/tamponade | Indicate whether the patient was reexplored for mediastinal bleeding with or without tamponade either in the ICU or returned to the operating room. | During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days. | 
| postoperative complications : Permanent stroke | Indicate whether the patient has a postoperative stroke (i.e., any confirmed neurological deficit of abrupt onset caused by a disturbance in blood supply to the brain) that was confirmed on imaging or did not resolve within 24 hours. | During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days. | 
| postoperative complications : Mortality | all deaths, regardless of cause, occurring during the hospitalization in which the operation was performed, even if after 30 days (including patients transferred to other acute care facilities) | During the hospitalization in which the operation was performed, even if after 30 days. | 
| postoperative complications : Mortality | all deaths, regardless of cause, occurring after discharge from the hospital, but before the end of the 30th postoperative day. | After discharge from the hospital, but before the end of the 30th postoperative day. |