Sonification Embodied Associations

Study Overview
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Brief Summary
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The objective of this study to investigate, if learning and recall of a sequence of body movements (steps that realize a pattern on the ground) can be improved by self-produced music (having particular melodic-structures in relation to the pattern), compared to the same sound (a single tone) for each pattern in persons with multiple sclerosis compared to age and gender matched controls

Official Title
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Investigating Auditory Sonification (Melodic and Single Tones) and Visual Real-time Feedback as a Tool for Embodied Associations, and Its Effects on Learning and Balance in Persons With Multiple Sclerosis

Conditions
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Multiple Sclerosis

Intervention / Treatment
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* Other: learning and recall of a sequence of body movements


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Time up and Go (TUG) test: 8 sec -- > 21 sec Exclusion Criteria: cognitive impairment hindering the understanding and execution of the experimental procedures, pregnancy, hearing impairment, amusia beat deafness, colour blindness.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: persons with Multiple Sclerosis (MS)<br> | Other: learning and recall of a sequence of body movements<br>* The objective of this study to investigate, if learning and recall of a sequence of body movements (steps that realize a pattern on the ground) can be improved by self-produced music (having particular melodic-structures in relation to the pattern), compared to the same sound (a single tone) for each pattern in persons<br>|
| Other: Healthy controls<br> | Other: learning and recall of a sequence of body movements<br>* The objective of this study to investigate, if learning and recall of a sequence of body movements (steps that realize a pattern on the ground) can be improved by self-produced music (having particular melodic-structures in relation to the pattern), compared to the same sound (a single tone) for each pattern in persons<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| accuracy | Number of correct sequences uttered, total number of sequences, precisions prior to completing three correct trials. | week 1 | 
| precision | Number of correct sequences uttered, total number of sequences, precisions prior to completing three correct trials. | week 1 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Inter Step intervals | The technology used can log time data. Therefore, the inter-step intervals can be calculated from the logged data. | week 1 | 
| Inter Stride intervals | The technology used can log time data. Therefore, the inter stride intervals can be calculated from the logged data. | week 1 | 
| step duration on the tile | The technology used can log time data. Therefore, the total time that each foot is placed on the tiles can be derived. | week 1 |