Work Productivity and Social Activities In Patients With Ankylosing Spondylitis

Study Overview
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Brief Summary
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The aim of this study is to evaluate the relationship between decrease in work productivity and social activities in patients with Ankylosing Spondylitis (AS) with disease activity, depression and quality of life together with demographic data.

Detailed Description
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For this study, which is planned as a cross-sectional clinical study, 100 patients who were diagnosed with AS between the ages of 18-65 and who applied to the Istanbul Physical Therapy Rehabilitation SUAM Physical Medicine and Rehabilitation Outpatient Clinic between April 15, 2019, and April 15, 2020, and 100 healthy volunteers compatible with age. was included. Demographic data of the participants were recorded. Work productivity and activity reduction questionnaire: general health (WPAI: GH), social role participation questionnaire short form (SRPQ), short form-36 (SF-36), hospital anxiety, and depression scale (HADS), will be evaluated. Besides, if the patient group exists, laboratory results (CRP, erythrocyte sedimentation rate, HLA-B27), and bath ankylosing spondylitis functional index (BASFI), bath ankylosing spondylitis disease activity index (BASDAI), Bath ankylosing spondylitis metrology index (BASMI), visual analog scale (VAS) resting, night and activity values were recorded.

Official Title
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The Relationship Between The Decreasing Activity, Depression And Quality Of Life In Work Productivity And Social Activities In Ankylosing Spondylitis Patients: A Randomized Controlled Trial

Conditions
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Ankylosing Spondylitis, Work Productivity

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients with AS diagnosis between the ages of 18-65 Healthy volunteer individuals between the ages of 18-65 without known musculoskeletal disease Exclusion Criteria: Those with serious systemic diseases that may interfere with working (respiratory system, cardiovascular system, renal and metabolic diseases) Those with orthopedic and psychiatric diseases Those with inflammatory diseases other than known AS Pregnant People with disability due to the history of trauma Those with injury after the operation Those with diseases that cause neurological sequelae

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Ankylosing Spondylitis<br>100 patients who were diagnosed with AS between the ages of 18-65 | |
| Healthy Volunteers<br>100 healthy volunteers compatible with age. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Work Productivity and Activity Impairment Questionnaire: General Health V2.0 (WPAI:GH) | WPAI: GH measures health impact and symptom severity impact on work productivity and leave time effectiveness | One day | 
| Social Role Participation Questionnaire (SRPQ) | It is used to evaluate integration into society and activities in social life. It evaluates the level of participation in six social roles in two dimensions: the experienced physical difficulties scale and the role performance satisfaction scale. Participants complete their satisfaction and challenges during their social roles | One day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Short Form Health Survey 36 (SF-36) | used to evaluate the quality of life | One day | 
| Hospital Anxiety and Depression Scale (HADS) | used to determine the risk in terms of anxiety and depression in a patient with a physical illness, and to measure the level and change of severity. | One day | 
| Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) | the assessment of disease activity in patients with ankylosing spondylitis | One day | 
| Bath Ankylosing Spondylitis Functional Index (BASFI) | the assessment of functional status in patients with ankylosing spondylitis | One day | 
| Bath Ankylosing Spondylitis Metrology Index (BASMI) | the assessment of the level of spinal mobility in patients with ankylosing spondylitis | One day | 
| Ankylosing Spondylitis Quality of Life (ASQoL) | used to evaluate the quality of life in patients with ankylosing spondylitis | One day | 
| Visual Analogue Scale (VAS) | used to evaluate the pain | One day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Spondylitis, Ankylosing, Quality of Life, Employment