Exercise Exposure Data Collection in Patients Undergoing Tumor Molecular Profiling

Study Overview
=================
Brief Summary
-----------------
This study will recruit approximately 5,000 patients with histologically confirmed cancer who have successfully completed MSK-IMPACT panel testing and collect information about tumor genetic results and patient exercise behavior history. The purpose of the study is to create a registry to collect exercise behavior history in patients who had IMPACT genetic panel testing on protocol IRB #12-245 Genomic Profiling in Cancer Patients, IRB #06-107 Storage and Research Use of Human Biospecimens, or IRB #09-141 Collection of Human Biological Specimens from Patients for Research Studies. The investigators want to find a way to create an exercise database. This database will collect information about tumor genetic results and patient exercise behavior history.

Official Title
-----------------
Exercise Exposure Data Collection in Patients Undergoing Tumor Molecular Profiling

Conditions
-----------------
Cancer, Carcinoma

Intervention / Treatment
-----------------
* Behavioral: Prior Exercise Behavior Questions - Harvard Health Professionals Exercise Questionnaire
* Behavioral: Current Exercise Behavior Questions: International Physical Activity Questionnaire Short Form (IPAQ SF)


Participation Criteria
=================
Eligibility Criteria
-----------------
Cohort 1: IMPACT Cohort Inclusion Criteria: Histologically-confirmed cancer. IMPACT testing with completed genomic profile completed within three years of initial recruitment approach Registered to Memorial Sloan Kettering Cancer Center protocol IRB# 12-245 and/or IRB #06-107 and/or IRB # 09-141 ≥ 18 years of age ECOG Performance Status of 0 or 1 Exclusion Criteria: Unable to speak and read English Not willing to provide informed consent

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| MSK-IMPACT genetic panel testing<br>Participants have completed MSK-IMPACT genetic panel testing on Memorial Sloan Kettering Cancer Center protocol IRB #12-245 and/or IRB #06-107 and/or IRB # 09-141 in the last 3 years. | Behavioral: Prior Exercise Behavior Questions - Harvard Health Professionals Exercise Questionnaire<br>* Participants will be asked how often on average over the year prior to their most recent diagnosis they participated in walking or hiking; jogging; running; calisthenics, aerobics, rowing, Nordic track; bicycling; tennis, squash, racquetball; lap swimming; weightlifting; and other aerobic exercise (e.g. heavy outdoor work), as well as their usual walking pace and flights of stairs climbed daily over the past 12 months prior to diagnosis.<br>Behavioral: Current Exercise Behavior Questions: International Physical Activity Questionnaire Short Form (IPAQ SF)<br>* The purpose of this questionnaire is to provide common instruments that can be used to obtain internationally comparable data on exercise exposure in adults aged 15 to 80 years old.<br>* Other names: IPAQ SF;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Characterize exercise participant behavior history via exercise survey | Participants who have undergone MSK-IMPACT panel testing will complete the exercise history survey. The 10 minute survey only asks participants about their exercise history, both in period before their most recent diagnosis as well as their current exercise behavior. | Up to 5 years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Histologically confirmed cancer, IMPACT testing, 17-327