Dynamic Imaging of the Hip for Pre-operative Planning

Study Overview
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Brief Summary
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One of the leading causes of hip arthritis is femoro-acetabular impingement which means the hip joint is deformed such that the hip joint jams in the front when the hip is bent all the way forward. This can lead to significant damage to the hip joint and may result in the need for a total hip replacement. However, if detected early, this deformity can be treated surgically by reshaping the hip joint. If the hip joint could be better visualized before surgery, then surgeons would be able to develop less invasive surgical techniques to correct this deformity.

Detailed Description
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In this study, we are trying to develop a way to help surgeons visualize the hip joint before surgery in order to assist with pre-operative planning. This will be done by comparing the dynamic hip images in patients with femoroacetabular impingement to the hip images of healthy volunteers with no hip problems.

Official Title
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Hip Reconstruction and Modeling for Surgical Pre-Operative Planning

Conditions
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Femoroacetabular, Impingement

Intervention / Treatment
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* Procedure: Motion analysis
* Diagnostic Test: Computed Tomography


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All participants (patients and controls) must be between the ages of 18 and 55, with a BMI less than 35. The patients must have a probable diagnosis of femoro-acetabular impingement (FAI). Their hip pain must have been ongoing for at least 3 months. The controls must have a normal hip as defined by AP pelvis radiographs. Exclusion Criteria: Participants (patients and controls) will be excluded if they are pregnant, have a knee injury or replacement, or history of childhood hip disease. Patients will be excluded if have they have arthritis, previous fracture or trauma to the hip, previous hip surgery, dysplasia, or avascular necrosis. Controls will be excluded if they have hip pain.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 55 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: FAI patients<br>This group consists of participants diagnosed with femoroacetabular impingement that are undergoing surgical correction. | Procedure: Motion analysis<br>* Participants will undergo a motion analysis procedure: a dynamic assessment of the movement in their hip.<br>Diagnostic Test: Computed Tomography<br>* Participants will undergo computed tomography (CT) scan of their hip.<br>|
| Placebo Comparator: Control<br>This group consists of healthy control participants with no hip problems. | Procedure: Motion analysis<br>* Participants will undergo a motion analysis procedure: a dynamic assessment of the movement in their hip.<br>Diagnostic Test: Computed Tomography<br>* Participants will undergo computed tomography (CT) scan of their hip.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Validation of kinematic model of hip joint | Development of a kinematical model of the hip joint to simulate virtual joint motion. This will be done by using automatic segmentation using the CT data to generate models. | Within 6 months of recruitment | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Joint Kinetics | Retro-reflective markers will be placed on each participant in a laboratory setting. Joint kinematics will be reconstructed from marker trajectories recorded by a camera system. Together, with EMG data, the investigators will calculate joint kinetics | 24 months | 
| Muscle Activity | Retro-reflective markers will be placed on each participant in a laboratory setting. Electromyography (EMG) electrodes will be placed on the skin above the tibialis anterior, medial and lateral gastrocnemius, vastus lateralis and medialis, biceps femoris, semitendinosis and gluteus maximums of both limbs. Muscle activity will be measured using EMG signal recorded during activity. | 24 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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femoroacetabular, impingement