A Longitudinal Study of Movement and Participation in Life Activities of Young Children With Cerebral Palsy in Taiwan

Study Overview
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Brief Summary
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This study investigates the longitudinal course of developmental patterns in movement and participation in life activities (MPLA) of young children with cerebral palsy (CP) in Taiwan. Additionally, the predictors in the initial stage in determining the final developmental patterns in movement and participation in life activities MPLA of these children will be identified.

Detailed Description
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Most researches investigated the longitudinal study of functions in adolescent or adult with CP, however, few researches investigate these functions in children with CP. Knowledge of these developmental patterns in movement and participation in life activities MPLA may be helpful in understanding, anticipating, and managing the problems of these children. We hypothesize that the course of developmental patterns in MPLA of young children with CP evolves with their age. This study investigates the longitudinal course of developmental patterns in MPLA of young children with CP in Taiwan. This study includes a validity and reliability study and a prospective longitudinal study of young children with CP over one-year. This study will be executed in 4 years and a validity and reliability study in the first year.

Official Title
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A Longitudinal Study of Movement and Participation in Life Activities of Young Children With Cerebral Palsy in Taiwan

Conditions
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Cerebral Palsy

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: diagnosis of CP Exclusion Criteria: presence of a progressive neurological disorder or a severe concurrent illness or disease not typically associated with CP, such as traumatic brain injury or active pneumonia

Ages Eligible for Study
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Minimum Age: 3 Months
Maximum Age: 12 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change of speech and acoustic variables in 6, 12 and 24 months | Measurement of speech and acoustic variables | baseline, 6m, 12m, 24 m | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change of range of motion (ROM) in 6, 12 and 24 months | Measurement of ROM | baseline, 6m, 12m, 24 m | 
| Change of Pediatric Berg Balance Scale (PBS) in 6, 12 and 24 months | Measurement of PBS | baseline, 6m, 12m, 24 m | 
| Change of spinal Alignment and Range of Motion Measure(SARROM) in 6, 12 and 24 months | Measurement of SARROM | baseline, 6m, 12m, 24 m | 
| Change of modified ashworth scale(MAS) in 6, 12 and 24 months | Measurement of MAS | baseline, 6m, 12m, 24 m | 
| Change of cerebral palsy quality of life (CPQOL) in 6, 12 and 24 months | Measurement of CPQOL | baseline, 6m, 12m, 24 m | 
| Change of TNO-AZL Preschool children Quality of Life (TAPQOL)in 6, 12 and 24 months | Measurement of TAPQOL | baseline, 6m, 12m, 24 m | 
| Change of Children Assessment of Participation and Enjoyment (CAPE) in 6, 12 and 24 months | Measurement of CAPE | baseline, 6m, 12m, 24 m | 
| Change of Gross motor function measure (GMFM) in 6, 12 and 24 months | Measurement of GMFM | baseline, 6m, 12m, 24 m |