Tongue Edema Caused by Intubation Tube in Intensive Care Unit Patients

Study Overview
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Brief Summary
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Tongue edema (TE) is an enlargement of the tongue that can be noticed with the naked eye and protrudes from the mouth. Endotracheal intubation tube, which can exert high pressure on the tongue for a long time, may cause TE. This study was aimed to detect TE, which may develop due to long-term pressure application of the intubation tube to the tongue, in patients hospitalized in the intensive care unit (ICU) who underwent endotracheal intubation by submental ultrasonography (USG) method.

Detailed Description
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Tongue edema (TE) is an enlargement of the tongue that can be noticed with the naked eye and protrudes from the mouth. Endotracheal intubation tube, which can exert high pressure on the tongue for a long time, may cause TE. This study was aimed to detect TE, which may develop due to long-term pressure application of the intubation tube to the tongue, in patients hospitalized in the intensive care unit (ICU) who underwent endotracheal intubation by submental ultrasonography (USG) method.

Official Title
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Detection of Tongue Edema Caused by Intubation Tube in Intensive Care Unit Patients by Ultrasonography

Conditions
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Tongue Edema, Tongue Enlarged, Mechanical Ventilation Complication, Intubation Complication

Intervention / Treatment
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* Diagnostic Test: Measuring tongue cross-sectional area by submental ultrasonography


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients aged between 18-65 years Patients who underwent endotracheal intubation and were admitted to the intensive care unit on the 0th day of intubation and patients who underwent endotracheal intubation during follow-up in the intensive care unit and were followed up on a mechanical ventilator - Exclusion Criteria: Patients under the age of 18 and over the age of 65 Patients who had a history of maxillofacial trauma, tongue surgery, head and neck malignancy, radiotherapy to the head and neck region, congenital anomalies of the tongue base and floor of the mouth Patients who were admitted to the intensive care unit due to allergy-anaphylaxis -

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Study Group<br>Patients followed up with a mechanical ventilator for 4 days or longer were included in the study group. | Diagnostic Test: Measuring tongue cross-sectional area by submental ultrasonography<br>* The tongue cross-sectional areas of both groups were measured with submental ultrasonography to detect tongue edema.<br>|
| Control Group<br>Patients followed up with mechanical ventilation for 3 days or less were included in the control group. | Diagnostic Test: Measuring tongue cross-sectional area by submental ultrasonography<br>* The tongue cross-sectional areas of both groups were measured with submental ultrasonography to detect tongue edema.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Detection of tongue edema by ultrasonography | Primary outcome was tongue edema which is likely to develop due to the pressure exerted by endotracheal intubation tube on the tongue, by submental ultrasonography in patients who were followed up on mechanical ventilation for a long time. | The patients' tongue cross-sectional areas were measured by submental ultrasonograph on the 0th day of endotracheal intubation and 4th day of follow-up on a mechanical ventilator. The difference between the two measurements was evaluated as tongue edema. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The effect of drugs applied in the intensive care unit on the development of tongue edema | Secondary outcome was tongue edema which is likely to develop due to the drugs applied in the intensive care unit by submental ultrasonography. | The patients' tongue cross-sectional areas were measured by submental ultrasonograph on the 0th day of endotracheal intubation and 4th day of follow-up on a mechanical ventilator. The difference between the two measurements was evaluated as tongue edema. | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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ultrasonography, endotracheal intubation tube, complication, drugs, tongue edema