Rehabilitation Following Laparoscopic Colonic Surgery

Study Overview
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Brief Summary
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The standard procedure for treating colonic cancer is changing from open surgery to laparoscopic surgery. Following open colonic surgery patients are fatigued and loss body mass and have a reduction in physical function, but the investigators do not know if this is also the case following laparoscopic surgery. This study examines how fatigue, quality of life, physical function, and body composition changes following laparoscopic colonic surgery. Patients are examined preoperatively and postoperative day 10 and 30.

Official Title
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Changes in Fatigue and Physical Function Following Laparoscopic Colonic Surgery

Conditions
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Colonic Cancer, Postoperative Care, Fatigue

Intervention / Treatment
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* Procedure: Laparoscopic colonic surgery


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: elective colonic cancer surgery hemicolectomy or sigmoid resection informed consent Exclusion Criteria: disseminated cancer contraindications for laparoscopic surgery dementia or serious psychiatric disease diseases or other aspects that prohibit participation
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: Laparoscopic surgery<br>Patients undergoing laparoscopic colonic surgery are compared with a historical cohort of patients undergoing similar open colonic surgery (right hemicolectomy and sigmoid resections). | Procedure: Laparoscopic colonic surgery<br>* Laparoscopic removal of colonic cancer<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Fatigue |  | Preoperative to postoperative day 10 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Muscular strength |  | From preoperatively to postoperative day 10 and 30 | 
| Change in work capacity (pulse rate) |  | From pre- to postoperative day 10 and 30 | 
| Balance (sway) |  | From preoperatively to postoperative day 10 and 30 | 
| Pain at rest and when moving |  | From preoperatively to postoperative day 10 and 30 | 
| Quality of life (Short Form 36 - SF-36) |  | From preoperatively to postoperative day 10 and 30 | 
| Body weight |  | From preoperatively to postoperative day 30 | 
| Body composition (fat mass and fat free mass estimated by bio-impedance) |  | From preoperatively to postoperative day 10 and 30 | 
| Social support |  | From preoperatively to postoperative day 10 and 30 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Colonic surgery, Postoperative care, Fatigue, Physical function, Quality of life