linjc16/ctgov huggingface dataset:
BECOME PATIENTS IN THE EMERGENCIES OF UHC POITIERS

Study Overview
=================
Brief Summary
-----------------
The number of consultations in the emergency services has continued to increase with 19.7 million passages in 2014, an increase of 4% compared to 2013. Among these admissions, many patients come spontaneously to the emergency department and others are sent by the general practitioner who remains the first resort in the care of the patient. Faced with this massive influx to emergency services, the investigator will see what is the future of these. Are they more likely to be hospitalized than patients presenting to emergencies on their own?

Official Title
-----------------
ANALYSIS OF THE BECOME OF THE PATIENTS ADDRESSED BY THEIR GENERAL PRACTITIONER TO EMERGENCIES OF UHC POITIERS

Conditions
-----------------
Emergencies

Intervention / Treatment
-----------------
* Other: Real care course


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Major patient View by a general practitioner whether he is their doctor or a substitute Addressed with a mail All types of pathologies are taken into account Exclusion Criteria: Minor patient

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 100 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Real care course|Evaluate the rate of adequacy between the request made by the general practitioner and the response to emergencies|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Concordance rate between the general practitioner request and the patient's actual care path. | Medical file | 1 day |
Patient Satisfaction in Cutaneous Surgery

Study Overview
=================
Brief Summary
-----------------
The primary objective of this study is to measure the overall level of satisfaction in patients after cutaneous surgery in 4 different categories, including the surgeon, facility, procedure and recovery and outcome.

Detailed Description
-----------------
Secondary objectives are to identify factors associated with patient satisfaction level and determine the correlation between patient satisfaction and surgeon clinical perception.

Official Title
-----------------
A Pilot Study of Patient Satisfaction After Cutaneous Surgery

Conditions
-----------------
Skin Cancer

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 18-80 years old Is in a self-reported stable health condition English speaking Is willing and has the ability to understand the study, provide informed consent and communicate with the investigator Recommended to have and scheduled for cutaneous surgery Agrees to follow-up at scheduled times Exclusion Criteria: Unable to speak or read English Did not complete an 8th grade education A history of mental illness Any other disability or condition that would prevent completion of questionnaire

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| cutaneous surgery<br>Patients undergoing cutaneous surgery | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Patient rating | Subjects will rate their satisfaction after cutaneous surgery in 4 different categories using 0-10 visual analog scales. The scale will be  100 millimeters in length and each response will be given a value in millimeters. In addition, patients will answer an open-ended question about their level of satisfaction. Data will also be compared to previous data from patients after cutaneous surgery in the literature. | at time of visit | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Patient ranking | Subjects will rank the factors determining satisfaction in order of importance using a ranking system for each aspect of care. In addition, the surgeon will rate their satisfaction level and give their perception on patient satisfaction and communication level using 0-10 visual analog scales | at time of visit |
Safety and Efficacy of QAX576 in Adults With Moderate Persistent Allergic Asthma

Study Overview
=================
Brief Summary
-----------------
This study will evaluate the safety and efficacy of QAX576 against asthma attacks in adults with moderate persistent allergic asthma

Official Title
-----------------
A Randomized, Double-blinded, Placebo Controlled, Parallel Group, Multi-center Study to Assess Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of Intravenous Doses of QAX576 in Moderate Persistent Allergic Asthmatics Following Inhaled Corticosteroid Withdrawal

Conditions
-----------------
Asthma

Intervention / Treatment
-----------------
* Drug: QAX576
* Drug: Placebo


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: History of asthma attacks Taking inhaled corticosteroids Non-smoking Exclusion Criteria: Women of child-bearing potential History of respiratory disease other than asthma History of severe allergy to food or drugs Previous use of monoclonal antibodies Very low or high body weight Other protocol-defined inclusion/exclusion criteria may apply.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 55 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 1<br> | Drug: QAX576<br> <br> |
| Placebo Comparator: 2<br> | Drug: Placebo<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| - Forced expiratory volume in 1 second (FEV1)at baseline and until study completion - Levels of eosinophils in sputum |  | Throughout the study | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| - Three doses of QAX576 on time to treatment failure, plasma IL-13 levels and immunogenicity in asthmatics - Sputum biomarkers |  | Throughout the study | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Asthma, interleukin-13
Type 1 Diabetes Data Acquisition and Transfer Adherence Study

Study Overview
=================
Brief Summary
-----------------
The purpose of this pilot study is to determine if training and support, combined with reminders to facilitate glucose data sharing with the diabetes care team in between clinic visits, can improve glycemic outcomes for patients ages 10-17 with type 1 diabetes who have HbA1c levels above target.

Official Title
-----------------
Type 1 Diabetes Data Acquisition and Transfer Adherence Study

Conditions
-----------------
Type 1 Diabetes Mellitus

Intervention / Treatment
-----------------
* Behavioral: Glooko MeterSync


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Diagnosis with T1D at least 6 months before consent is obtained Aged ≥ 2 years and ≤17 years at time of enrollment Must have access to a smartphone, tablet or computer at home with wireless connectivity Last HbA1c of ≥7.6% and ≤11% Using fixed doses, multiple daily injections or an insulin pump as primary diabetes management regimen Ability to read and speak English Patient at UF Health Pediatric Diabetes Clinic Exclusion Criteria: Significant medical comorbidity in the child or adolescent that could, in the opinion of the PI, affect participant's capacity to complete study follow up Inability to read and speak English Not using insulin therapy Lack of access to mobile device or computer with wireless internet connectivity Unwilling or unable to use clinic's software (Glooko) to facilitate glucose data upload

Ages Eligible for Study
-----------------
Minimum Age: 2 Years
Maximum Age: 17 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Intervention Group<br>Participants will be provided with training on how to upload glucose data via GLOOKO and will receive reminders to upload glucose data on a biweekly basis between clinic visits. | Behavioral: Glooko MeterSync<br>* The participant and caregiver will receive a reminder via text or email to upload glucose data via Glooko on a biweekly basis.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Improved glycemic control | HbA1c | 16 weeks | 
| Frequency of data upload | The number of times glucose data is uploaded between clinic visits | 16 weeks |
The Influence of a High Intensity Physical Activity Intervention on a Selection of Health Related Outcomes: An Ecological Approach

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to determine whether a High Intensity exercise intervention can elicit cardiovascular disease protection in adolescents.

Conditions
-----------------
To Assess the Impact of the HIT Intervention on Physiological Responses, To Assess the Role of a Secondary High School as a Setting for Promoting Healthy Eating and PA Behaviours, To Determine the Associations Between CVD Risk Factors at Baseline in 15 - 18 Year Old Youth

Intervention / Treatment
-----------------
* Behavioral: High Intensity Exercise


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Healthy 15 - 18 yer old that are capable of performing vigorous exercise Exclusion Criteria: Any health condition that would prevent them from undertaking vigorous exercise

Ages Eligible for Study
-----------------
Minimum Age: 15 Years
Maximum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: High Intensity Exercise<br> | Behavioral: High Intensity Exercise<br>* In this study, participants will be instructed to sprint maximally for a period of 30 seconds. Following 30s rest, the participants will be instructed to repeat this procedure a further 3 times. This equates to 2 minutes of maximal effort sprinting interspersed with 2 minutes recovery. Participants will be requested to perform this protocol 3 times weekly. Training progression will be implemented by increasing the number of repeats from four repetitions during weeks 1 and 2, to five repetitions during weeks 3 and 4, to six repetitions during weeks 5 and 6. Finally, during week 7 participants will still perform six repetitions but interspersed by only 20 s recovery.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To improve blood lipid profiles and lower levels of plasma inflammatory markers. |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To determine the associations between CVD risk factors at baseline in 15 - 18 year old youth. |  |  | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Public Health, Biochemistry, Ecological
Telomeres Parameters in Cirrhosis

Study Overview
=================
Brief Summary
-----------------
There are several factors that influence telomere length in patients with cirrhosis, such as metabolic derangements and infectious etiologies, The aim of the study is to compare telomere length and other parameters related to genetic instability in telomere/ telomerase system, in peripheral blood lymphocytes in cirrhosis from different etiologies.

Conditions
-----------------
Cirrhosis

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: cirrhotic patients from different etiologies Exclusion Criteria: decompensated cirrhosis (Child C) age under 18 years any known malignancy, including hepatocellular carcinoma patient that are unable to sign for informed consent

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| cirrhosis<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| telomerase activity | number of copies of telomerase in peripheral blood lymphocytes, as determined by FISH | baseline | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
telomere, telomerase, cirrhosis
Does Stellate Ganglion Block Decrease Stress Response of Intubation?

Study Overview
=================
Brief Summary
-----------------
In this study investigators will evaluate the effect of stellate ganglion block on stress response of intubation in comparison to traditional antistress measures in adult patients

Detailed Description
-----------------
Both groups will have the same general anesthesia procedure, patients in stellate block group will receive lidocaine in the stellate block will in control group patients will receive Na.Cl as placebo. primary outcome will be stress response to subsequent endotracheal intubation measure by changes in heart rate

Official Title
-----------------
Does Stellate Ganglion Block Decrease Stress Response of Intubation?

Conditions
-----------------
Intubation, Stellate Ganglion

Intervention / Treatment
-----------------
* Procedure: stellate block
* Drug: Na.Cl 0.9% (placebo)
* Drug: lidocaine 2%


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Elective surgery General anesthesia with endotracheal intubation ASA I/II Exclusion Criteria: Pregnancy Hypersensitivity to local anesthetics Coagulopathy Infection at site of injection Patient refusal

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 60 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: stellate block<br>patients in this arm will receive ultrasonographic guided left stellate block with 6 ml of lidocaine 2% after routine induction of general anesthesia and before endotracheal intubation | Procedure: stellate block<br> <br> * Other names: cervicothoracic ganglion block;Drug: lidocaine 2%<br> <br> |
| Placebo Comparator: control<br>patients in this arm will receive ultrasonographic guided left stellate block with 6 ml normal saline (Na.Cl 0.9%) (control group) after routine induction of general anesthesia and before endotracheal intubation | Procedure: stellate block<br> <br> * Other names: cervicothoracic ganglion block;Drug: Na.Cl 0.9% (placebo)<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| heart rate | measured in beat/min. | 5 minutes | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| mean arterial blood pressure | measured in mm.Hg | 5 minutes |
Lamictal Bipolar Observational Study

Study Overview
=================
Brief Summary
-----------------
This is multi-center, prospective, observational stud. This study is designed to evaluate the rate of non-serious rash in Korean bipolar I patients.

Official Title
-----------------
A Multi-centre, Observational Study to Evaluate the Incidence of Non-serious Rash in Korean Bipolar I Patients With Lamotrigine Therapy in Real World Setting

Conditions
-----------------
Bipolar Disorder

Intervention / Treatment
-----------------
* Drug: lamotrigine


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion criteria: A subject will be eligible for inclusion in this study only if all of the following criteria apply: Provides written informed consent Male or female age 18 years or older A female subject is eligible to enter and participate in the study if she is of; Non-childbearing potential Childbearing potential, has a negative pregnancy test at screen Diagnosis of bipolar I disorder using DSM-IV criteria Exclusion criteria: A subject will not be eligible for inclusion in this study if any of the following criteria apply: Previous or current treatment with lamotrigine Presence of a clinically significant psychiatric or physiologic comorbidity, including significant substance abuse, severe depression or mania which is of an unstable or progressive nature that could, in the opinion of the investigator, interfere with participation in this study Presence of untreated thyroid disease Have active suicidality or homicidality, history of recent suicide attempts within the past year, or, in the investigator's opinion, a marked risk for suicide History of severe hepatic or renal insufficiency or significant hematologic disease or other significant medical or psychiatric condition that would interfere with subjects' participation in the study Currently participating in another clinical trial, or plans to enroll in another trial while participating in this study Currently pregnant or is breastfeeding

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| lamotrigine<br>there is only one group. | Drug: lamotrigine<br>* lamotrigine treatment for 12weeks<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Occurrence of non-serious rash during 12 weeks of treatment with lamotrigine in patients with bipolar I in Korea |  | 12 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| CGI-BP at Week 12 and occurrence of adverse events at Week 12 |  | 12 weeks | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Korean, Bipolar I disorder, Non-serious rash, Lamotrigine
Comparison of Traditional Superficial Cutaneous Sutures Versus Steri-Strip Coaptive Film in Layered Dermatologic Closures

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to compare the cosmetic outcome between buried intradermal and superficial cutaneous suture closures versus buried intradermal sutureand superficial Steri-Strip closures in the bilayered repair of dermatologic wounds on the back following elliptical excision of benign or malignant lesions

Official Title
-----------------
Comparison of Traditional Superficial Cutaneous Sutures Versus Steri-Strip Coaptive Film in Layered Dermatologic Closures on the Back - a Prospective, Randomized, Split-scar Study

Conditions
-----------------
Wound Cosmesis

Intervention / Treatment
-----------------
* Other: Steri-Strip
* Other: Superficial sutures


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 18 years or greater in age Simple excision of benign or malignant lesion on the back Final scar length of at least 3cm Exclusion Criteria: Known history of keloid formation or hypertrophic scars Known adhesive allergy Pregnancy or active breast feeding

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Surgical excision<br> | Other: Steri-Strip<br> <br> Other: Superficial sutures<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Overall scar appearance as evaluated by the Patient and Observer Scar Assessment Scale |  | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rates of postoperative complications | Assessment of scar erythema, swelling, infection, drainage, dehiscence | 6 months | 
| Time for closure of each split half portion of wound |  | 1 hour (intraoperative) | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Scar, Appearance