Clinical Follow up After Subtotal and Total Hysterectomy

Study Overview
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Brief Summary
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The purpose of this study was to find out subjective and objective outcomes of patients undergoing subtotal or total abdominal hysterectomy during a follow up of a mean 33 years after the operation. The hypothesis is that there are similar outcomes after both types of operations.

Detailed Description
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Objective: To evaluate ultra long-term follow-up after subtotal and total hysterectomy in patients operated on during 1978-1979 in Turku University Hospital, Finland. Methods: From the original cohort of 212 patients 193 were sent a postal questionnaire in 1997 to find out possible symptoms related to hysterectomy. Again in 2011 a questionnaire based evaluation with a possibility of a clinical visit to study hospital was done for 153 patients. In the first evaluation a self-made questionnaire and in the second evaluation validated questionnaires were used. During a follow-up visit a clinical examination using also POP-Q-system was done. Additionally, hospital records of the patients were reviewed to find out subsequent operations after hysterectomy.

Official Title
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Ultra Long-term Follow-up of the Outcome After Subtotal Versus Total Abdominal Hysterectomy

Conditions
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Abdominal Hysterectomy (& Wertheim)

Intervention / Treatment
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* Procedure: Subtotal abdominal hysterectomy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: benign indication for hysterectomy Exclusion Criteria: abnormal Pap smear
Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Subtotal abdominal hysterectomy<br>107 women | Procedure: Subtotal abdominal hysterectomy<br>* Comparison of women undergoing subtotal abdominal hysterectomy (n=107) and women with total abdominal hysterectomy (n=105) a mean of 33 years ago.<br>* Other names: Total abdominal hysterectomy;|
| Total abdominal hysterectomy<br>105 women | Procedure: Subtotal abdominal hysterectomy<br>* Comparison of women undergoing subtotal abdominal hysterectomy (n=107) and women with total abdominal hysterectomy (n=105) a mean of 33 years ago.<br>* Other names: Total abdominal hysterectomy;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of participants having subjective symptoms after hysterectomy | Urinary and bowel symptoms assessed with questionnaires and Visual Analog Scale. Sexual symptoms assessed with questionnaire. | 19 years and 33 years postoperatively | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Objective evaluation of pelvic organ prolapse after hysterectomy | Gynecological examination and measurements using pelvic organ prolapse quantification system (POP-Q) to find out the number of participants having prolapse. | 33 years postoperatively | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Hysterectomy, long term follow up, subjective outcome