Effects of Pilates Method and Aerobic Training in Hypertensive Subjects

Study Overview
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Brief Summary
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This study evaluates the effects of Pilates method and aerobic training in hypertensive subjects. Half of participants will be trained with Pilates, while the other half will be trained with aerobic exercise during 8 weeks.

Official Title
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Effects of Pilates Method and Aerobic Training in Hypertensive Subjects: a Randomized Trial

Conditions
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Hypertension

Intervention / Treatment
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* Other: Aerobic Exercise
* Other: Pilates


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: subjects with high blood pressure controled by medication; sedentary. Exclusion Criteria: IMC≥30 kg/m² using beta blockers smokers or that interrupted the routine less than 6 months musculoskeletal diseases in evolution or with current symptomatic rheumatological diseases other cardiovascular disease renal disease due to hypertension endocrine, neurological, oncological, immunological, hematological and psychiatric diseases.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Pilates method group<br>The participants will do Mat Pilates. | Other: Pilates<br>* 1 hour of Mat Pilates, 2 times a week, during 8 weeks.<br>* Other names: Mat Pilates;|
| Active Comparator: Aerobic training group<br>The participants will do aerobic exercise on treadmill. | Other: Aerobic Exercise<br>* 1 hour of aerobic training on a treadmill, 3 times a week, during 8 weeks.<br>* Other names: aerobic training;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change from baseline casual systolic blood pressure at 8 weeks | It will be evaluated with oscillometric method of measuring blood pressure with an automated cuff. | baseline and 8 weeks | 
| Change from baseline 24-hour systolic blood pressure at 8 weeks | It will be evaluated by 24-hour ambulatory BP monitoring (ABPM) | baseline and 8 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Casual diastolic blood pressure | It will be evaluated with oscillometric method of measuring blood pressure with an automated cuff. | baseline and 8 weeks | 
| Heart rate variability | It will be evaluated using a previously validated heart rate monitor Polar 810i, and the results will be analyzed in time- and frequency-domains. | baseline and 8 weeks | 
| Diastolic and mean blood pressure | It will be evaluated by 24-hour ambulatory BP monitoring (ABPM) | baseline and 8 weeks | 
| Functional capacity | Evaluate by Six-Minute Walk Test (6MWT) | baseline and 8 weeks | 
| Respiratory muscle strength | The maximal inspiratory and expiratory pressures will be evaluated with manovacuometer | baseline and 8 weeks | 
| Muscle strength | The muscles (quadriceps, gastrocnemius, abdominal and spine extensors) will be evaluated with dynamometer. | baseline and 8 weeks | 
| Flexibility | It will be evaluated by bank of Wells test. | baseline and 8 weeks | 
| Body Mass Index | It will be calculated as weight (kg) divided by height squared. | baseline and 8 weeks | 
| Oxidative damage | It will be evaluated by advanced oxidation protein products (AOPP) | baseline and 8 weeks | 
| Antioxidant capacity | It will be evaluated by total antioxidant capacity (TAC). | baseline and 8 weeks | 
| Lipid profile | By blood analysis (LDL, HDL, total cholesterol, glucose and triglycerides). | baseline and 8 weeks | 
| Endothelial function | By blood analysis (Nitrite measurement/NOx). | baseline and 8 weeks | 
| Inflammation | It will be evaluated by C-reactive protein in blood analysis | baseline and 8 weeks | 
| Creatinine | By blood analysis | baseline and 8 weeks | 
| Lactate | By blood analysis | baselina and 8 weeks | 
| Creatine kinase | By blood analysis | baseline and 8 weeks | 
| Questionnaire of Quality of life | It will be evaluated by Mini-questionnaire of Quality of Life in Hypertension (MINICHAL) | baseline and 8 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Hypertension, Pilates Training, Aerobic Exercises, Clinical trial