Evaluation of Quality of Life and Its Influencing Factors After VA-ECMO in Refractory Cardiac Arrest Based on SF-36 Score : A Grenoble Cohort Study From 2006 Through 2018

Study Overview
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Brief Summary
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If the ExtraCorporeal Membrane Oxygenation (ECMO) improves survival in the management of refractory cardiac arrest (RCA), this technique is still an invasive technique, not devoid of complications and requiring intensive care that can have serious consequences for patients. If the studies so far show an acceptable quality of life post ECMO in refractory cardiac arrest, the study looks about the quality of life of our patients in Grenoble who survived a refractory cardiac arrest between 2006 and 2018 at the hospital university Grenoble Alps and the factors influencing this quality of life.

Official Title
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Evaluation of Quality of Life and Its Influencing Factors After VA-ECMO in Refractory Cardiac Arrest Based on SF-36 Score : A Grenoble Cohort Study From 2006 Through 2018

Conditions
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Refractory Cardiac Arrest, ExtraCorporeal Membrane Oxygenation (ECMO)

Intervention / Treatment
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* Other: SF36 questionnaire via telephone interview


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adult >18 years Admission to intensive care unit after a Refractory Cardiac Arrest Hemodynamic instability after resumption of spontaneous cardiac activity. Non-opposition of the patient or his relatives Admission to intensive care unit From 2006 Through 2018 Exclusion Criteria: ECMO for hypothermia or drug intoxication. Comorbidity contraindicated the ECMO Patients dead before hospital discharge

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Live patients admitted for Refractory Cardiac Arrest with ECMO<br> | Other: SF36 questionnaire via telephone interview<br>* SF36 questionnaire via telephone interview<br>|
| Live patients quality of life admitted for Refractory Cardiac Arrest without ECMO<br> | Other: SF36 questionnaire via telephone interview<br>* SF36 questionnaire via telephone interview<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Global quality of life score | Items from the SF36 (Short Form 36) survey | Through study completion, an average of 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Live patients characteristics description | Demographic and clinical retrospective data collection | Through study completion, an average of 3 months | 
| Vital status | Deed/Lived | Through study completion, an average of 3 months | 
| Quality of life score related at live patients characteristics description | Items from the SF36 (Short Form 36) survey matched with live patients characteristics description | Through study completion, an average of 3 months | 
| Quality of life score comparison | Items from the SF36 (Short Form 36) survey compared between the 2 groups ( RCA with /without ECMO) admitted from january 2015 and december 2018 | Through study completion, an average of 3 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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ExtraCorporeal Membrane Oxygenation (ECMO), Refractory Cardiac Arrest, Quality life assessement (SF36 QUESTIONNAIRE)