Symfony Intraocular Lens Retrospective Chart Review

Study Overview
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Brief Summary
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Retrospective chart review of patients with pre-existing ocular pathology who underwent cataract surgery with implantation of the Symfony IOL.

Detailed Description
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This was a retrospective chart review conducted at a single US clinical site. Chart review was conducted by John Odette, MD and research assistants. Eligible charts were identified via a clinic database search of cataract surgeries with IOL implantation of the Symfony IOL during the stated date range. Eligible charts included those of patients 18 to 90 years of age who underwent Femto Laser Assisted Cataract Surgery (FLACS) with implantation of a Symfony IOL. Charts were excluded for lack of postoperative follow-up or if Symfony IOL was not implanted. All qualifying patient charts were examined and further classified into 2 groups: (1) eyes with glaucoma; and 2) eyes without glaucoma. Visual acuity was evaluated for patients who underwent cataract surgery with implantation of the Symfony IOL from 09/1/2016 to 05/31/2018. Postoperative evaluations at Month 2 included mean monocular uncorrected visual acuity at near (UNVA) at 40 cm, far distance (UDVA) at 20 ft, and with best correction (CDVA). Outcomes were also compared for toric IOLs versus spherical IOL.

Official Title
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Experience With Symfony Extended Depth of Focus (EDOF) IOL: A Retrospective Chart Review

Conditions
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Cataract

Intervention / Treatment
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* Device: Symfony IOL


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: :Phacoemulsification cataract surgery with a Symfony IOL. Exclusion Criteria: : Eyes not implanted with a Symfony IOL or unstable refractive results at final post-operative visit

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 90 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Non-Pathology Eyes<br>Cataract Surgery with implantation of Symfony IOL in eyes without pre-existing pathology.. | Device: Symfony IOL<br>* Implantation of Intraocular lens with extended depth of focus.<br>|
| Glaucoma Eyes<br>Cataract Surgery with implantation of Symfony IOL with pre-existing glaucoma. | Device: Symfony IOL<br>* Implantation of Intraocular lens with extended depth of focus.<br>|
| Retinopathy Eyes<br>Cataract Surgery with implantation of Symfony IOL in eyes with pre-existing retinal pathology.. | Device: Symfony IOL<br>* Implantation of Intraocular lens with extended depth of focus.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Monocular uncorrected near visual acuity | handheld near card (Jaeger scale) | 2 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Monocular best corrected distance visual acuity | Snellen Chart at 20 feet | 2 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Retinopathy, Cataract surgery, Glaucoma, Intraocular Lens