OSS-IRM: Optimization of MRI Sequences in Healthy Volunteers

Study Overview
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Brief Summary
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Using MRI, many technical parameters can be changed to optimize the diagnostic quality of the examination. The study is interventionnal because healthy volunteers are not supposed to have an MRI exam. The primary objective of this study is to optimize the imaging protocols and to validate the choice of the technical parameters in healthy volunteers. The quality of the images, cartographies or spectres will be compared to standard acquisitions. This evaluation will be based on qualitative visual criteria assessed by expert radiologists or on quantitative criteria assessed by data processing tools.

Detailed Description
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Using MRI, many technical parameters (sequence, parameters in the sequence, reconstruction method, etc.) can be changed to optimize the diagnostic quality of the examination. The primary objective of this study is to optimize the imaging protocols and to validate the choice of the technical parameters in healthy volunteers. The quality of the images, cartographies or spectres will be compared to standard acquisitions. This evaluation will be based on qualitative visual criteria assessed by expert radiologists or on quantitative criteria assessed by data processing tools. Prospective, single-center, observational MRI study A screening visit is planned to check the inclusion/non inclusion criteria followed by an imaging visit during which the MRI examination will be performed. Theses 2 visits are scheduled at the subject's convenience. The number of participations to the study is limited to 5 per year per subject.

Official Title
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OSS-IRM: Optimization of MRI Sequences in Healthy Volunteers

Conditions
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Healthy

Intervention / Treatment
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* Device: MRI data acquiring in healthy volunteers


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Male or female subject, Aged 18 or above Exclusion Criteria: Patient with any surgical clip, external clips, or any other ferromagnetic device, that is contraindicated for use in MRI Claustrophobic patient Pregnancy Breastfeeding Patients subject to major legal protection (safeguarding justice, guardianship, trusteeship), persons deprived of liberty No healthcare insurance

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: MRI data acquiring in healthy volunteers<br>MRI data acquiring in healthy volonteers | Device: MRI data acquiring in healthy volunteers<br>* The quality of the images, cartographies or spectres will be compared to standard acquisitions. This evaluation will be based on qualitative visual criteria assessed by expert radiologists or on quantitative criteria assessed by data processing tools<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| MRI data acquisition : quality of the images, cartographies or spectres | The quality of the images, cartographies or spectres will be compared to standard acquisitions. This evaluation will be based on qualitative visual criteria assessed by expert radiologists or on quantitative criteria assessed by data processing tools | 0.5 day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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optimize the imaging protocols, validate technical parameters in healthy volunteers