Clinical Evaluation of the Effect of LANAP as an Adjunct Treatment in Management of Patients With Chronic Periodontitis

Study Overview
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Brief Summary
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this study evaluate the effect of LANAP (Laser Assisted New Attachment Procedure) as an Adjunct Treatment in Management of Patients With Chronic Periodontitis and assay the effect of LANAP on periodontal indexes like BOP, CAL, probing depth

Detailed Description
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this study evaluate the effect of LANAP (Laser Assisted New Attachment Procedure) as an Adjunct Treatment in Management of Patients With Chronic Periodontitis and assay the effect of LANAP on periodontal indexes like BOP, CAL, probing depth in a split mouth design before treatment and after follow up sessions.

Official Title
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Clinical Evaluation of the Effect of LANAP (Laser Assisted New Attachment Procedure) as an Adjunct Treatment in Management of Patients With Chronic Periodontitis( Randomized Clinical Trial Study)

Conditions
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Periodontitis, Laser

Intervention / Treatment
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* Radiation: LANAP (Laser Assisted New Attachment Procedure)
* Radiation: LANAP off


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: definite diagnosis of chronic periodontitis with at least two teeth with periodontal pocket depth more than 4 mm in each side Exclusion Criteria: pregnant smoker systemic disease breast feeding

Ages Eligible for Study
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Minimum Age: 30 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: LANAP<br>LANAP (Laser Assisted New Attachment Procedure) | Radiation: LANAP (Laser Assisted New Attachment Procedure)<br>* radiation of Nd:YAG laser in periodontal pocket<br>|
| Placebo Comparator: LANAP off<br>laser therapy in off mode | Radiation: LANAP off<br>* radiation of Nd:YAG laser in off mode in periodontal pocket<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| change of periodontal pocket depth | depth of periodontal pocket of each tooth | 0,1,2,3,4,5,6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| change of Bleeding on Probing | sign of bleeding after 1 minutes post probing the tooth pocket | 0,1,2,3,4,5,6 month | 
| change of Full Mouth Bleeding Score | Bleeding Score of all teeth that is calculated by counting the Four dental levels that have sign of bleeding post probing (including , mesio-buccal,mid- buccal, disto-buccal and lingual) divided by the total number of total teeth in the mouth *4 | 0,1,2,3,4,5,6 month | 
| change of Clinical attachment loss | distance from depth of tooth sulcus to cemento-enamel junction | 0,1,2,3,4,5,6 month | 
| change of Full Mouth Plaque Score | the number of 4 surfaces of each tooth(mesiobuccal, mid buccal, disto buccal and lingual surfaces) that have plaque that is disclosed by disclosing tables , then counting the number of the colored surface of all teeth divided by the total number of total teeth in the mouth*4 | 0,1,2,3,4,5,6 month | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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LANAP, Periodontitis