Computerized Rotational Head Impulse Test-Vertical (crHIT-vertical)

Study Overview
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Brief Summary
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The purpose of this research study is to test whether a Computerized Rotational Head Impulse Test-Vertical (crHIT-vertical) is able to reliably evaluate the vertical semicircular canals in patients with vestibular dysfunctions.

Official Title
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Computerized Rotational Head Impulse Test-Vertical (crHIT-vertical)

Conditions
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Vestibular Function Tests

Intervention / Treatment
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* Device: Computerized Rotational Head Impulse Test ( crHIT)-Vertical


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Subjects must be willing to tolerate the placement of a set of goggles on their face Controls: no history of dizziness or imbalance normal responses on rotational chair testing Patients: persons clinically diagnosed with vestibular disorders Exclusion Criteria: Pregnancy Neurodegenerative diseases

Ages Eligible for Study
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Minimum Age: 22 Years
Maximum Age: 69 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: 66 patients (30 patients with surgically confirmed unilateral loss, 15 patients with absent ice water calorics and resulting from vestibular neuritis and 21 patients with vestibular migraine) 120 controls
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Vestibular dysfunction<br>66 patients: 30 patients with surgically confirmed unilateral loss, 15 patients with absent ice water calorics and resulting from vestibular neuritis and 21 patients with vestibular migraine | Device: Computerized Rotational Head Impulse Test ( crHIT)-Vertical<br>* Oculo-Motility and Positional Testing, Caloric Testing<br>* Other names: crHIT Vertical;|
| Other: Control<br>120 aged matched controls | Device: Computerized Rotational Head Impulse Test ( crHIT)-Vertical<br>* Oculo-Motility and Positional Testing, Caloric Testing<br>* Other names: crHIT Vertical;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Sensitivity and specificity of crHIT-vertical | How many participants are correctly identified as either having a vestibular dysfunction or being healthy controls | 9 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Subject discomfort - symptoms | Number of subjects indicating motion sickness symptoms during the crHIT test. If motion sickness is present subjects are asked to rate the symptoms of motion sickness and severity on scale 1 to 5, where 1 is minimum and 5 is severe. | 9 months | 
| Subject discomfort - test apparatus | Subjects rate the comfort of chair, head rest and goggle on scale 1 to 5, where 1 is very uncomfortable and 5 very comfortable. | 9 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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vestibular neuritis, vestibular migraine