Impact of Assistive Forces on Activities of Daily Living

Study Overview
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Brief Summary
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This study is a cross-sectional study investigating the impact of assistive forces applied by the body-weight support system the FLOAT on the study participants. The study is conducted at the University Hospital Balgrist in Zurich over a period of around 3 years. During this time measurements on approximately 140 able bodied subjects and 60 patients with an incomplete spinal cord injury will take place. The study participants are invited for a single visit of around 140 min duration to the University Hospital Balgrist. During this visit the study participants will repeatedly perform various activities of daily living (free walking, standing up and sitting down, stair climbing and balancing) with and without assistive forces from the body-weight support system. While performing the tasks, the study participants' motions and muscle activities will be measured to evaluate the naturalness of their movements. In addition, the collected data permits us to compare different movement patterns and make conclusions about effective and optimal movement support. Obtaining this knowledge will help us to shape the therapy of these activities to be tailored to the patients and to train these movements with the help of the FLOAT under optimal conditions.

Official Title
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Impact of Robotic Assistive Forces on the Performance of Activities of Daily Living

Conditions
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Spinal Cord Injury

Intervention / Treatment
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* Other: FLOAT


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Individuals with incomplete spinal cord injury (AIS C-D) or able bodied persons informed consent as documented by signature bodyweight < 120 kg Exclusion Criteria: a significant psychiatric or orthopedic diagnose any secondary neurological complications that may impact the outcome variables dermatological conditions (pressure ulcers, etc.) pacemaker or other implanted, electronic devices contraindications for FLOAT training inability or unwillingness to provide written informed consent or follow study procedures e.g. due to language problems psychological disorders, dementia, etc. known or suspected non-compliance, drug or alcohol abuse enrolment of the investigator, his/her family members, employees and other dependent persons

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: FLOAT-Support<br> | Other: FLOAT<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 3-dimensional kinematic analyses resulting in a detailed movement profile for each of the performed tasks |  | Once (single visit) around 140 minutes duration |