linjc16/ctgov huggingface dataset:
Capillary and Venous Blood Count Parameters

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to compare capillary blood count parameters with the corresponding venous samples to verify the hypothesis that capillary and venous blood count parameters are equivalent.

Detailed Description
-----------------
In patients with haematological diseases regular blood count analyses are necessary. In haematology, capillary blood count analyses became established in routine diagnostics. The method and procedure of capillary blood sampling is well accepted by both the patients and the medical personal for a long time. However, only venous values are generally accepted in clinical routine. It is important to know whether or how capillary blood gives discrepant results for the various parameters. Values for therapeutic decisions, e.g. transfusion, are only known for venous values. So far, there are only deficient data available. Therefore, the aim of this study is (i) to compare capillary blood count parameters with the corresponding venous samples to verify the hypothesis that capillary and venous blood count parameters are equivalent, (ii) to include an adequate large number of adult haematological patients (with low and high values) and healthy adults, (iii) to obtain difference values for conversation of measured capillary values into the corresponding venous values.

Official Title
-----------------
Comparison of Capillary and Venous Blood Count Parameters

Conditions
-----------------
Hematological Diseases, Healthy Volunteers

Intervention / Treatment
-----------------
* Procedure: blood sampling


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with haematological diseases ≥18 years Healthy volunteers ≥18 years Informed consent No participation in another study 3 month before and during the study Exclusion Criteria: Subjects <18 years Healthy subjects with acute or chronic infections and autoimmune or malignant diseases

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: blood sampling|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
blood count, capillary, venous, Adult, reference values
e-Health Coping Skills Training for Women Whose Partner Has a Drinking Problem

Study Overview
=================
Brief Summary
-----------------
This study evaluates web-based interventions to help women cope with the stress arising from living with a problem-drinking partner

Official Title
-----------------
eHealth Coping Skills Training for Women Whose Partner Has a Drinking Problem

Conditions
-----------------
Alcohol Abuse

Intervention / Treatment
-----------------
* Behavioral: eHealth Coping Skills Training
* Behavioral: eHealth Usual Web Care
* Behavioral: Coach Support


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Resides in New York State Fluent in English Male partner has an alcohol problem Computer access and smart phone Married or cohabiting Exclusion Criteria: Substance use disorder Serious Mental Disorder Participation in prior studies Severe relationship violence

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: eHealth Coping Skills Training + Coach<br>Access to StopSpinningMyWheels.org + Coach Support | Behavioral: eHealth Coping Skills Training<br>* Access to a specialized coping skills training website<br>Behavioral: Coach Support<br>* Access to a professional coach by phone<br>|
| Active Comparator: eHealth Coping Skills Training Only<br>Access to StopSpinningMyWheels.org | Behavioral: eHealth Coping Skills Training<br>* Access to a specialized coping skills training website<br>|
| Active Comparator: eHealth Usual Web Care<br>Access to StopSpinningMyWheels.org usual care | Behavioral: eHealth Usual Web Care<br>* Access to a website in which helpful information on coping that is available on the internet has been systematically collected and organized in one place for easy retrieval<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Beck Depression Inventory-II (BDI-II) Total Score | A measure of depressive symptoms. Scores range from 0 to 63. Lower scores are indicative of better outcomes. A score of 14 or higher is considered clinically relevant. | Change in BDI score up to 12 months postintervention | 
| State-Trait Anger Expression Inventory - 2 (STAXI-2, State Anger) | A measure of anger thoughts in their current state. Scores range from 1 to 60 with lower scores representing better outcomes. A score of 18 or above is considered clinically relevant. | Change in STAXI score up to 12 months postintervention |
An Extended Access Program (EAP) for Participants Who Have Completed Rufinamide Study E2080-G000-303

Study Overview
=================
Brief Summary
-----------------
This is an extended access study for participants who have completed Rufinamide Study E2080-G000-303 to continue to have access to rufinamide until it becomes commercially available in Poland or until no participants remain in the EAP.

Official Title
-----------------
An Extended Access Program (EAP) for Rufinamide in Pediatric Participants With Inadequately Controlled Lennox-Gastaut Syndrome

Conditions
-----------------
Lennox Gastaut Syndrome

Intervention / Treatment
-----------------
* Drug: Rufinamide


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Participants who were on rufinamide treatment and have completed Study E2080-G000-303 in Poland. Exclusion Criteria: Participants were randomized to the other antiepileptic drug (AED) treatment group in study E2080-G000-303.

Ages Eligible for Study
-----------------
Minimum Age: 4 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: Rufinamide|Rufinamide up to 45 milligram per kilogram per day (mg/kg/day).|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Central Nervous System, E2080, Rufinamide, Epilepsy, Seizures, Brain Diseases
Transverse B-Lynch in Management of Placenta Accreta

Study Overview
=================
Brief Summary
-----------------
Placenta accreta is considered a severe pregnancy complication that may be associated with massive and potentially life-threatening intrapartum and postpartum hemorrhage. Life-threatening bleeding is the most common complication to be associated with this condition; the average blood loss at time of delivery is reported to be 3000-5500 mL, which leads to significant postoperative morbidity and death.

Official Title
-----------------
Evaluation of the Efficacy of Transverse B-Lynch in Management of Placenta Accreta

Conditions
-----------------
Decrease Maternal Morbidity

Intervention / Treatment
-----------------
* Procedure: Transverse B-Lynch suture


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 1. All pregnant women with placenta previa as diagnosed by ultrasound with suspicion of abnormal placentation by Doppler us, confirmed intraoperatively undergoing either emergent or elective cesarean Exclusion Criteria: Patients who will be managed by hysterectomy Patients who will be managed by conservative leaving the placenta in-situ
Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: Transverse B-Lynch suture|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Estimated intraoperative blood loss |  | 30 min |
Study of Ice Application to Reduce Pain From Arterial Punctures

Study Overview
=================
Brief Summary
-----------------
This study seeks to determine if cryoanalgesia in the form of ice application could be an effective analgesic when applied before arterial puncture.

Official Title
-----------------
Cryoanalgesia (Ice Pack) to Reduce the Pain Associated With Arterial Blood Gas Puncture

Conditions
-----------------
Vessel Puncture Site Pain

Intervention / Treatment
-----------------
* Other: Cryotherapy (ice pack)


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: subjects ≥ 18 years old referred to the pulmonary function laboratory with a physician order for an arterial blood gas test were sought to complete the study Exclusion Criteria: cold, bluish hands and fingers diagnosis of Raynaud's syndrome or scleroderma/CREST syndrome history or signs of dementia, confusion, or cognitive impairment blindness patients not fluent in the English language non-palpable radial pulse in the wrist (necessitating brachial puncture)

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Cryotherapy<br>Cryotherapy: 12 ounces of crushed ice place in a plastic bag applied to the radial artery puncture area for 3 minutes | Other: Cryotherapy (ice pack)<br> <br> |
| No Intervention: Control<br>Cryotherapy is not applied to the radial artery puncture area | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| pain | Pain is measured with a 100 mm visual analog scale | 1-5 minutes after arterial puncture | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
ice, cryotherapy, puncture, pain
The Influence of PRN Omega-3 Nutritional Supplement on Visual Acuity

Study Overview
=================
Brief Summary
-----------------
This is a randomized, masked, placebo controlled study to assess the effect on visual acuity, if any, of the PRN omega-3 nutritional supplement in subjects undergoing cataract surgery.

Official Title
-----------------
The Influence of PRN Omega-3 Nutritional Supplement on Visual Acuity Outcomes In Cases Undergoing Cataract Surgery: A Pilot Study.

Conditions
-----------------
Cataract, Dry Eye Disease

Intervention / Treatment
-----------------
* Dietary Supplement: Omega-3 (Triglyceride form)


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Presence of nuclear or cortical lens opacities in one/both eyes Physician diagnosis of age related cataract Good overall physical constitution All participants must be follow the same regimen for surgery related medications, both pre and post surgery. (Antibiotic, NSAID and Steroid eye drops) Exclusion Criteria: Subjects requiring Premium IOLs/multifocal implants Advanced cataract Severe Age-Related Macular Degeneration Presence or history of Glaucoma Presence or history of Diabetes Mellitus Any Retinal pathology - retinal detachment, retinitis pigmentosa, diabetic retinopathy, etc Vision loss due to Central retinal artery occlusion or Central retinal vein occlusion Vision loss due to presence of large pituitary tumors or aneurysms Vision loss due to optic tract lesions Vision loss due to bleeding into aqueous or vitreous chamber Vision loss due to drug toxicity: Amiodarone, anti-tuberculosis drugs, hydroxychloroquine, tamoxifen Major cardiovascular or cerebral events in the past 12 months Allergy to fish oil or safflower oil Pregnancy or lactation at any time during the study Newly started or increased the dose of chronic systemic medication known to affect tear production including, but not limited to antihistamines, antidepressants, diuretics, corticosteroids or immunomodulators within 30 days of Screening or at any time during the study Participation in any other study involving an investigational drug or device within the past 30 days

Ages Eligible for Study
-----------------
Minimum Age: 30 Years
Maximum Age: 90 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Omega-3<br>re esterified TG omega-3 | Dietary Supplement: Omega-3 (Triglyceride form)<br> <br> |
| Placebo Comparator: Safflower Oil<br>vegetable oil | Dietary Supplement: Omega-3 (Triglyceride form)<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual Acuity |  | 8 weeks |
Physiological Response of Cortisol to Cardiac Catheterization

Study Overview
=================
Brief Summary
-----------------
Cortisol is essential for survival. The importance of cortisol response is most apparent in patients with partial or complete deficiency of glucocorticoids during stressful events such as illness or surgery.

Detailed Description
-----------------
It is known that cortisol and other stress hormones increase during acute myocardial infarction as well (9-11). Cardiac catheterization is an essential tool for the management of acute coronary syndrome, and for the evaluation of the burden of coronary artery disease in cardiac patients.

Official Title
-----------------
Physiological Response of Cortisol to Cardiac Catheterization

Conditions
-----------------
Adrenal Insufficiency

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients undergoing elective cardiac catheterization, who are willing and able to give consent. Exclusion Criteria: • Patients with .primary or secondary adrenal insufficiency. Patients taking steroids in the doses equivalent of at least 5 mg of prednisone daily for more than 3 weeks in the previous year. Patients undergoing cardiac catheterization in the setting of acute coronary syndrome, eg. STEMI, NSTEMI and unstable angina. Patients with low albumin level (<3.5 g/dL)

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 90 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| catheterization<br>patients undergoing elective heart catheterization | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| cortisol change | On the day of the procedure a total of 4 venous blood samples for random plasma cortisol level will be obtained. Blood will be drawn at 5 minutes prior to the procedure, at 30 minutes and 60 minutes during the cardiac catheterization. Another sample will be drawn in 3 hours after cardiac catheterization prior to the patients discharge. a cortisol level will be drawn at a nonstressful visit | one month | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
adrenal, steroids, cortisol, stress
Risk Factors for Shoulder Pain and Emesis After Laparoscopic Cholecystectomy

Study Overview
=================
Brief Summary
-----------------
Risk factors for postoperative shoulder pain after laparoscopic cholecystectomy were not clear. Moreover, risk factors for postoperative emesis specially for this surgery were not detailed and accurate. The present study is a prospective cohort study to identify risk factors for shoulder pain and emesis within 24 hours in Chinese patients after laparoscopic cholecystectomy under general anesthesia.

Detailed Description
-----------------
The present study is a prospective cohort study to identify risk factors for shoulder pain and emesis within 24 hours in Chinese patients after laparoscopic cholecystectomy under general anesthesia.

Official Title
-----------------
The Observational Cohort Study to Identify Risk Factors for Shoulder Pain and Emesis After Laparoscopic Cholecystectomy Under General Anesthesia

Conditions
-----------------
Shoulder Pain, Nausea, Vomiting

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: > 21 years old, Chinese patient Exclusion Criteria: current pregnancy, patients with history of upper laparotomy, inability to communicate before operation, persistent emesis or shoulder pain before operation, patients who converted to open cholecystectomy, receiving postoperative ventilator support, unstable postoperative condition or major complications.

Ages Eligible for Study
-----------------
Minimum Age: 21 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| incidence of postoperative shoulder pain and emesis |  | within postoperative 24 hours | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
laparoscopic cholecystectomy, elective, anesthesia, general, shoulder pain, nausea, vomiting, laparoscopic cholecystectomy, general anesthesia
The Effects of a 16-Week Individualized, Intensive Strength Training Program in Patients With Rheumatoid Arthritis

Study Overview
=================
Brief Summary
-----------------
To assess the effects of a 16-week individualized, intensive strength training program in patients with rheumatoid arthritis. Primary and secondary outcomes include: strength and body composition, function, disease activity, pain, quality of life. We hypothesized that improvements would be seen in all of the above outcomes.

Official Title
-----------------
The Strength Training and Remicade Study

Conditions
-----------------
Rheumatoid Arthritis

Intervention / Treatment
-----------------
* Behavioral: strength training


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Males and females with RA Over 18 years of age ACR Functional Class I and II Taking Remicade >4 months Exclusion Criteria: Presence of comorbid conditions contraindicated to exercise, including, but not limited to: heart disease severe osteoporosis: (if >50 years): T score < -3.0 for hip or spine excluded; T score <-2.5 for hip or spine w/o current treatment) (all potential subjects) previous non-traumatic fractures uncontrolled BP BMI >40 Regular use of assistive walking device which would interfere with ability to lift weights Currently or within the last 3 months participating in aerobic exercise > 150 minutes a week Currently or within the last 3 months participating in any regular strength training activities Presence of neurological impairment that directly limits ability to perform exercise Participation in concurrent exercise study Any reason for which the investigator deems it would not be in the patient's best interest to continue in the study Plans to move away from site within next 1 year

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: strength training|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Strength |  |  | 
| Body Composition |  |  | 
| Function |  |  | 
| Pain |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Quality of Life |  |  | 
| Disease Activity |  |  | 
| Fatigue |  |  |
Multiparas Attitude to Outpatient Cesarean Section

Study Overview
=================
Brief Summary
-----------------
The main purpose of this study is to explore multiparas attitude to outpatient care after a planned cesarean section.

Detailed Description
-----------------
This qualitative study should provide information about: Multiparas reflections in relation to prefer inpatient care after a planned cesarean section Womens anticipation of having inpatient care after cesarean section The womens experiences in relation to a planned cesarean birth and the first postnatal weeks

Official Title
-----------------
Multiparas Attitude to Outpatient Care After Cesarean Section - A Qualitative Study

Conditions
-----------------
Postpartum Complication

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Planned elective cesarean section of multiparous women Singleton pregnancy Age of at least 18 Gestational age between 37 and 42 weeks Exclusion Criteria: Lack of consent Women with no or little understanding of Danish and ability to speak Danish. Allergies to medicine included in the pain management regimes Expected maternal or neonatal complications after delivery Birth weight of less than 2500 grams
Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Multiparas, planned cesarean section<br>Multiparas having a planned cesarean section at the departement of Obstetrics and Gynecology in Herning Hospital. Uncomplicated pregnancy that makes early discharge possible. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| womens attitude an reflections about based on interviews |  | october 2013- june 2014 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
qualitative, planned cesarean section, outpatient care, Multiparas attitude