Application of a Dental-dedicated MRI in the Diagnosis of Temporomandibular Joint Disorders, Tissue Alterations Related to Third Molars, Periapical and Periodontal Inflammatory Diseases, and Implant Treatment Planning

Study Overview
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Brief Summary
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The aim of the present study is to show that the use of 0.55T MRI combined with a dental coil produces images of sufficient diagnostic value to assess areas of interest in dentistry, and to compare MR images to traditional, dental-oriented radiographic images for diagnostic purposes.

Official Title
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Application of a Dental-dedicated MRI in the Diagnosis of Temporomandibular Joint Disorders, Tissue Alterations Related to Third Molars, Periapical and Periodontal Inflammatory Diseases, and Implant Planning

Conditions
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TMJ, Apical Periodontitis, Periodontal Inflammation, Retained Tooth, MRI

Intervention / Treatment
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* Device: MRI of teeth and surrounding structures


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria (one of the following): referred for CBCT imaging of at least one tooth for endodontic reasons referred for intra-oral and/or panoramic imaging covering at least one molar tooth for periodontal reasons referred for CBCT imaging of the TMJ (bilaterally) referred for panoramic imaging of the third molar (retained/semi-retained, uni- or bilateral), prior to treatment planning referred for CBCT imaging prior to implant treatment Exclusion Criteria: younger than 18 years unable to give consent pregnant pronounced claustrophobia pacemakers or implanted defibrillators metal shrapnel injuries of the eyes or MRI incompatible metallic inclusions or implants large tatoos non-removable piercings

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Interventional Model Description: Each person has a MRI scan done following the requested radiograph. MRI and radiographs are compared for diagnostic purposes.
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Application of a dental-dedicated MRI<br>MRI of conditions related to teeth and surrounding structures | Device: MRI of teeth and surrounding structures<br>* included above<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Application of a dental-dedicated MRI in the diagnosis of temporomandibular joint disorders, tissue alterations related to third molars, periapical and periodontal inflammatory diseases, and implant treatment planning | Diagnosis of pathologies in the TMJ (e.g. disc displacement (anterior/posterior/lateral), inflammation (yes/no), bone changes (yes/no)), periodontal defects (e.g. bone defects (mm), inflammation (yes/no)), periapical pathology (e.g. inflammation (yes/no), apical periodontitis (yes/no)), bone measurements in edentulous areas, and third molars (e.g. relation to surrounding structures (over/same level/under nerve), resorption of neighboring teeth (yes/no)) seen on MRI compared to diagnosis obtained in radiographs. Observations seen on MRI will be compared to observations seen in radiographs. | 2½ years |