Cochlear Implantation Among Adults and Older Children With Unilateral or Asymmetric Hearing Loss

Study Overview
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Brief Summary
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Do adults and children over 7 years of age with unilateral or assymetric hearing loss benefit from cochlear implantation on the worst hearing side.

Detailed Description
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Unilateral hearing loss is known to impair binaural hearing abilities. Specifically, localization, speech understanding in noise, and binaural squelch suffer due to lack of binaural timing and level cues. This study is designed to examine how binaural hearing is improved following cochlear implantation on the impaired side. The study endpoints are collected at 6 months and 12 months post activation of the implant. This is not a funded study. All costs are billed through insurance for reimbursement. There is an insurance approval process that we move through after a participant has been evaluated at the Mayo Clinic and found to be a candidate for cochlear implantation.

Official Title
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Cochlear Implantation Among Adults and Older Children With Unilateral or Asymmetric Hearing Loss

Conditions
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Severe Unilateral Sensorineural Hearing Loss

Intervention / Treatment
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* Device: Cochlear implant


Participation Criteria
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Eligibility Criteria
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Adults 18 years of age or older, Hearing loss in the ear to be implanted must such that speech understanding is not possible with a well fitted hearing aid. Specifically, less than 40% monosyllabic word understanding when that ear is tested in the best-aided condition and the other ear is sufficiently occluded or masked. Onset of hearing loss in the adult group must be post-lingual (after three years of age) Children Children 7 years of age and older Hearing loss in the ear to be implanted configured such that word understanding is less 40% in the best aided condition Onset of hearing loss in the pediatric group must be post-lingual (after three years of age)

Ages Eligible for Study
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Minimum Age: 7 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| cochlear implant<br>How well patients with cochlear implants understand speech in noise with implant on, compared to implant off. | Device: Cochlear implant<br>* Implantable hearing device<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Listening Effort | A dual task performance paradigm will be used in which both the primary task and the secondary task will be performed simultaneously. The primary task will consist of speech recognition testing in varying levels of background noise and quiet, whereas the secondary task will consist of a motor reaction to a randomly presented light | one year post operative test time | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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cochlear implant