TURP; Complications and Outpatient Care

Study Overview
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Brief Summary
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This study aims to investigate the impact of transurethral prostate resection in regard to complications. These are direct surgical complications, such as bleeding, infection and readmissions, as well as the long term complications as incontinence and impotence. Also, the study aims to investigate if selected cases of patients could be performed as outpatient surgery, thereby reducing cost.

Detailed Description
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Transuretral prostate resection (TUR P) is a common procedure to relieve voiding problems in men. After the introduction of bipolar resection with saline, the serious complication of transurethral resection syndrome (i.e. acute hypo-natremia) has been eradicated. The post surgical care is generally a couple of days inhospital care. The reson for this, is the risk of clot formation and in rare cases post surgical infection. However, in selected cases, outpatient surgery has been performed with encouraging results. However, the technique has not been spread widely. The use of ambulatory surgery would reduce the direct cost of the procedure, thereby increasing it´s availability. Also, complications in contemporary TUR P in the modern era (outside of the selected patients of clinical trials) is lacking. The information of complications that can be expected is therefore an important for patient counseling. In some studies, the use of incontinence pads after TUR P is more than 15%, which is important to reliably ascertain if this is holds true.

Official Title
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Bipolar Transurethral Resection of the Prostate; Complications and Possibility to do as Outpatient Procedure

Conditions
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Benign Prostatic Hyperplasia

Intervention / Treatment
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* Procedure: transurethral resection of the prostate


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Planned for transurethral resection of the prostate (TUR P) Exclusion Criteria: No consent to participate
Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: transurethral resection of the prostate|Surgical removal of benign prostatic tissue|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Proportion of patients able to be discharged the day of surgery |  | One day | 
| Proportion of patients readmitted to hospital the first day of surgery |  | One day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in IPSS score | International prostate symptom score, range 0-35 | 6 months | 
| Number of patients with cancer in surgical specimen | Pathological confirmed prostate cancer, all Gleasson Grades (6-10) | 6 months | 
| Readmission rates within 30 days of surgery |  | 30 days | 
| Complications | Clavien Dindo Classification | 30 days | 
| Proportion catheter free |  | 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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prostate, resection, incontinence, erectile dysfunction