Red Cell Distribution Width,,NT-proBNP and cTnT in Acute Myocardial Infraction Patient

Study Overview
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Brief Summary
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the study is to investigate the relationship of several parameters of complete blood count (CBC) including RDW with N-terminal pro-B-type natriuretic peptide (NT-proBNP) and cardiac troponin T (cTnT) in a cohort of acute myocardial infarction (AMI) patients.

Detailed Description
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Patients and methods: Type of study: Observational prospective study Place of study: Sohag cardiology and gastroenterology center, department of cardiology and cardiac care unit. Ethical considerations: This research will be revised by the Scientific Ethical Committee of Sohag University Hospital. Consents will be taken from all patients. Study Methods: A prospective study on 30 patients diagnosed as acute myocardial infarction on which measurement of CBC, serum NT-proBNP, and cTnT levels will be performed at the time of admission and by the time of discharge. All patients included in the study will be subjected to: Full history: Personal history: e.g. age, sex and smoking. Family history of cardiac diseases Medical history of: Hypertension, Ischemic heart disease, prior coronary artery bypass grafting, Prior Percutaneous coronary intervention, Prior Stroke, Prior Atrial fibrillation, therapeutic history Detailed clinical examination Electrocardiogram Laboratory investigation: Routine investigation in the form of CBC including RDW Specific investigation which include NT-proBNP and cTnT

Official Title
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Detrmination of the Relationship Between Red Cell Distribution Width ,NT-proBNP and cTnT in Acute Myocardial Infraction Patients

Conditions
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Myocardial Infarction

Intervention / Treatment
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* Diagnostic Test: (CBC) ,(NT-proBNP) ,(cTnT)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients diagnosed as acute myocardial infarction and admitted to department of cardiology and cardiac care unit at Sohag cardiology and gastroenterology center according to inclusion and exclution criteria Exclusion Criteria: Patient with: Decompensated heart failure Pulmonary hypertention Acute pulmonary embolism Septic shock
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: (CBC) ,(NT-proBNP) ,(cTnT)|complete blood count (CBC) including RDW with N-terminal pro-B-type natriuretic peptide (NT-proBNP) and cardiac troponin T (cTnT) in a cohort of acute myocardial infarction (AMI) patients.|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| (CBC) | measurement of CBC will be performed at the time of admission and by the time of discharge. | 6 months | 
| (NT-proBNP | measurement of serum NT-proBNP levels will be performed at the time of admission and by the time of discharge. | 6 months | 
| (cTnT) | measurement of cTnT levels will be performed at the time of admission and by the time of discharge | 6 months |