Arrhythmogenic Risk Assessment in Coronary Artery Ectasia Patients

Study Overview
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Brief Summary
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The investigators thought to explore arrhythmias outcome - hidden arrhythmias, ECG features: Tp-Te interval and Tp-Te/QTc ratio, fQRS among patients with coronary artery ectasia as compared to normal coronary artery patients.

Detailed Description
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All patients will be subjected to: A. Full history taking: - Including age, sex, history of DM, HTN, dyslipidemia and Body surface area. B. Holter monitoring for 24 hours: Heart rate variability Hidden arrhythmias Hidden ischemia by monitoring ST segment changes C. Twelve lead ECG: fQRS in baseline ECG QT dispersion. Tp-Te interval and Tp-Te/QTc ratio Tp-Te dispersion

Official Title
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Arrhythmogenic Risk Assessment in Coronary Artery Ectasia Patients

Conditions
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Coronary Artery Ectasia

Intervention / Treatment
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* Diagnostic Test: Holter, ECG


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Subjects with suspected CAD who are referred for elective coronary angiography and/or interventions Exclusion Criteria: Patients with a history of cardiomyopathy and myocardial infarction (MI), left ventricular hypertrophy (LVH), pathological Q wave on ECG, typical left bundle block or right bundle block, incomplete right bundle block, or paced rhythm on ECG. Patients with severe renal impairment Post CABG patients Patients of acute coronary syndrome

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Coronary Artery Ectasia patients<br> | Diagnostic Test: Holter, ECG<br>* Incidence of arrhythmias in Holter monitoring among coronary artery ectasia patients as compared to normal coronary artery patients.<br>|
| Normal coronary artery patients<br> | Diagnostic Test: Holter, ECG<br>* Incidence of arrhythmias in Holter monitoring among coronary artery ectasia patients as compared to normal coronary artery patients.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Precence of arrhythmias in 24 hours Holter monitoring | Incidence of arrhythmias in Holter monitoring among coronary artery ectasia patients as compared to normal coronary artery patients. | 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| • Heart rate variability in Holter monitoring | Heart rate variability in Holter monitoring among coronary artery ectasia patients as compared to normal coronary artery patients. | 1 year | 
| • Silent ischemia as detected by Holter | Presence pf ischemia in Holter monitoring among coronary artery ectasia patients as compared to normal coronary artery patients. | 1 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Coronary artery ectasia