Resting Energy Expenditure of the COronaVirus (COVID19) Patient in Reanimation Context

Study Overview
=================
Brief Summary
-----------------
Compare the resting energy expenditure of COVID-19 patients (obese or non-obese) in intensive care unit with mechanical ventilation to a control group of non-COVID-19 intensive care patients.

Official Title
-----------------
Resting Energy Expenditure of the COronaVirus (COVID19) Patient in Reanimation Context

Conditions
-----------------
COVID-19, Obesity

Intervention / Treatment
-----------------
* Diagnostic Test: indirect calorimetry


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: For the Ambulatory Obese Control Group, the inclusion criteria are: Age ≥ 18 years; Patient followed in the nutrition service; Patient who benefited from an indirect calorimetry whatever the indication between 01/01/20 and 31/12/2020; BMI> 30. For the COVID Group and the Resuscitation Control Group, the inclusion criteria are: Age ≥ 18 years; Patient having undergone a resuscitation stay Patient on mechanical ventilation (intubated or tracheotomized) during their stay in intensive care; Patient having benefited from an indirect calorimetry upon arrival in intensive care; Only for the COVID Group: Patient hospitalized in intensive care for COVID 19 infection diagnosed by a positive PCR via nasopharyngeal sampling or endotracheal aspiration. Patient who has not yet carried out his post-resuscitation visit; Only for the Resuscitation Control Group: - Patient hospitalized in intensive care for an indication other than an infectious cause. Exclusion Criteria: Non-inclusion criteria for the Ambulatory Obese Control Group: Person deprived of liberty; Person subject to legal protection measures; Patient's opposition to participate in research. The non-inclusion criteria for the COVID Group and the Resuscitation Control Group: For patients intubated during the resuscitation stay Fi02> 70% which does not allow a correct interpretation of the calorimetry; Pregnancy ; Person deprived of liberty; Person subject to legal protection measures; Opposition of the patient or the person of trust to participate in the research. Only for the COVID Group: Contraindication to indirect calorimetry (claustrophobia for post-resuscitation patients where calorimetry is performed with a mask); Contraindication to bioimpedancemetry (electronic implants, limb amputation, weight <30kg or> 300kg);

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| COVID intensive care unit<br> | Diagnostic Test: indirect calorimetry<br>* to determine and compare the resting energy expenditure of each group<br>|
| intensive care unit<br> | Diagnostic Test: indirect calorimetry<br>* to determine and compare the resting energy expenditure of each group<br>|
| obesity<br> | Diagnostic Test: indirect calorimetry<br>* to determine and compare the resting energy expenditure of each group<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The resting energy expenditure (in Kcal / 24h) measured by indirect calorimetry during the stay in intensive care. |  | baseline and 3 months later | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
resting energy expenditure, artificial nutrition