Effect of Inferior Alveolar and Gow-Gates Nerve Block Techniques for Symptomatic Mandibular Molars

Study Overview
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Brief Summary
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Introduction: to evaluate the efficacy of inferior alveolar nerve block (IANB), Gow-Gates nerve block (GGNB), and their combination in patients with irreversible pulpitis. Methods: One hundred fifty subjects with irreversible pulpitis of a mandibular molar were selected. subjects randomly received two IANB injections or two GGNB injections or their combination of 1.8 mL 2% lidocaine with 1:100,000 epinephrine. Success was specified as no or mild pain on the basis of Heft-Parker visual analogue scale recordings up on the access cavity preparation or initial instrumentation. Data were analyzed by Kruskal-Wallis, and ANOVA tests.

Detailed Description
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Introduction: to evaluate the efficacy of inferior alveolar nerve block (IANB), Gow-Gates nerve block (GGNB), and their combination in patients with irreversible pulpitis. Methods: One hundred fifty subjects with irreversible pulpitis of a mandibular molar were selected. subjects randomly received two IANB injections or two GGNB injections or their combination of 1.8 mL 2% lidocaine with 1:100,000 epinephrine. Success was specified as no or mild pain on the basis of Heft-Parker visual analogue scale recordings up on the access cavity preparation or initial instrumentation. Data were analyzed by Kruskal-Wallis, and ANOVA tests.

Official Title
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Effect of Inferior Alveolar and Gow-Gates Nerve Block Techniques for Symptomatic Mandibular Molars

Conditions
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Symptomatic Irreversible Pulpitis

Intervention / Treatment
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* Procedure: GGNB injections
* Procedure: IANB injections
* Procedure: GGNB + IANB injections


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: vital mandibular molar tooth diagnosis of symptomatic irreversible pulpitis Exclusion Criteria: younger than 18 years old history of significant medical conditions allergies to local anesthetics or sulfites pregnancy taking any medications that might influence anesthetic assessment active sites of pathosis in area of injection inability to give informed consent

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: GGNB injection technique<br>In GGNB group, every patient received two1.8-mL cartridges of 2% lidocaine with 1:80,000 epinephrine using the GGNB technique | Procedure: GGNB injections<br>* The patients received two GGNB injections of 1.8 mL 2% lidocaine with 1:100,000 epinephrine<br>|
| Active Comparator: IANB injection technique<br>In IANB group, every patient received two 1.8-mL cartridges of 2% lidocaine with 1:80,000 epinephrine using the IANB technique | Procedure: IANB injections<br>* The patients received two IANB injections of 1.8 mL 2% lidocaine with 1:100,000 epinephrine<br>|
| Active Comparator: GGNB + IANB injection technique<br>In IANB + GGNB group, every patient received one 1.8-mL cartridges of 2% lidocaine with 1:80,000 epinephrine using the IANB technique and one 1.8-mL cartridges of 2% lidocaine with 1:80,000 epinephrine using the GGNB technique | Procedure: GGNB + IANB injections<br>* The patients received one GGNB injection plus one IANB injection of 1.8 mL 2% lidocaine with 1:100,000 epinephrine<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the success rate of GGNB local anesthesia technique based on Heft-Parker visual analog scale |  | at time of access cavity preparation | 
| the success rate of IANB local anesthesia technique based on Heft-Parker visual analog scale |  | at time of access cavity preparation | 
| the success rate of GGNB + IANB local anesthesia techniques based on Heft-Parker visual analog scale |  | at time of access cavity preparation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| initial pain based on Heft-Parker visual analog scale |  | before treatment | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Gow-Gates nerve block, Inferior alveolar nerve block, local anesthesia, molar, pulpitis