Virtual Reality Experiences for Anxiety and Pain Control

Study Overview
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Brief Summary
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This trial studies the impact of virtual reality experiences on anxiety before surgery and pain after surgery. The goal of this study is to examine how different virtual reality experiences may help reduce anxiety and improve pain control, which may help reduce the need for medications such as opioids.

Detailed Description
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PRIMARY OBJECTIVE: I. To measure the impact of a gaming virtual reality (VR) experience compared to a mindfulness VR experience on preoperative anxiety and postoperative pain. OUTLINE: Patients are randomized to 1 of 2 arms. ARM I: Patients participate in a VR intervention (Angry Birds) over 15 minutes before standard of care surgery and then participate in a VR intervention (TRIPP) over 15 minutes after surgery. ARM II: Patients participate in a VR intervention (TRIPP) over 15 minutes before standard of care surgery and then participate in a VR intervention (Angry Birds) over 15 minutes after surgery.

Official Title
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Impact of Different Virtual Reality Experiences on Anxiety and Pain

Conditions
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Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm

Intervention / Treatment
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* Other: Survey Administration
* Procedure: Virtual Reality Game
* Procedure: Virtual Reality Meditation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adults (18 years or older and younger than 89) Able to consent English-speaking Exclusion Criteria: Non-English speaking patients because the VR content is only available in English Have symptoms concerning for an active respiratory infection or are on contact or isolation precautions Any active eye discharge A history of seizure, epilepsy, or hypersensitivity to flashing light Have a history of motion sickness or vertigo Have active nausea or vomiting Psychiatric conditions that may interfere with the ability to successfully participate in the study Have cardiac pacemakers Require hearing aids at all times that cannot be removed Have defibrillators Have wound dressings on the head or neck that prevent comfortable use of the VR headset

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 89 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Arm I (Angry Birds, TRIPP)<br>Patients participate in a VR intervention (Angry Birds) over 15 minutes before standard of care surgery and then participate in a VR intervention (TRIPP) over 15 minutes after surgery. | Other: Survey Administration<br>* Ancillary studies<br>Procedure: Virtual Reality Game<br>* Participate in VR Game Angry Birds<br>* Other names: VR Game;Procedure: Virtual Reality Meditation<br>* Participate in VR Meditation TRIPP<br>* Other names: VR Meditation;|
| Experimental: Arm II (TRIPP, Angry Birds)<br>Patients participate in a VR intervention (TRIPP) over 15 minutes before standard of care surgery and then participate in a VR intervention (Angry Birds) over 15 minutes after surgery. | Other: Survey Administration<br>* Ancillary studies<br>Procedure: Virtual Reality Game<br>* Participate in VR Game Angry Birds<br>* Other names: VR Game;Procedure: Virtual Reality Meditation<br>* Participate in VR Meditation TRIPP<br>* Other names: VR Meditation;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in preoperative anxiety scores | Assessed by visual analogue scale (VAS) from 0-100mm. | Baseline up to pre surgery (estimated 1 day) | 
| Change in postoperative pain scores | Assessed by VAS scale from 0-100mm. | Baseline after surgery up to study completion (estimated 1 day) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in blood pressure | mmHg | immediately before intervention, and then immediately after intervention (estimated 1 day) | 
| Patient enjoyment of each VR experience | Likert scale (1-5). 1 represents the lowest score, and 5 represents the highest. | Up to study completion (estimated 1 day) | 
| Change in heart rate | beats per minute (bpm) | immediately before intervention, and then immediately after intervention (estimated 1 day) | 
| Patient desire to use VR more in their healthcare | Likert scale (1-5). 1 represents the lowest score, and 5 represents the highest. | Up to study completion (estimated 1 day) |