Working Memory Training in Young ADHD Children

Study Overview
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Brief Summary
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The purpose of this study is to investigate whether working memory training improves behavioral symptoms, neurocognitive performance, and neural functioning in young children with ADHD.

Official Title
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Working Memory Training: A Randomised Controlled Treatment Study in Young ADHD Children

Conditions
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Attention Deficit Disorder With Hyperactivity

Intervention / Treatment
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* Behavioral: Cogmed Working memory training
* Behavioral: Control version of Cogmed working memory training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age between 4 years/6 months and 7 years/4 months Diagnosis ADHD, classified by the DSM-IV (Diagnostic and Statistical Manual of Mental Disorders, 2000) A full scale IQ >= 80 Psychopharmaca- naïve or -free Access to a PC with Windows Vista or Windows XP with internet connection and speakers at home Exclusion Criteria: Currently intensive (i.e. weekly) individual or group psychotherapy Regular use of medication Diagnosis of one or more of the following comorbid psychiatric disorders: Major depression, Bipolar disorder, Psychotic disorder, Chronically motor tic disorder or Gilles de la Tourette, Conduct disorder, any other autism spectrum disorder except for Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS), Eating disorders, Anxiety disorders Neurological disorders (e.g. epilepsy) currently or in the past Cardiovascular disease currently or in the past Serious motor or perceptual handicap Participation in another clinical trial simultaneously Educational level and/ or socio-economic situation that makes it unlikely for the family to fulfil this study

Ages Eligible for Study
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Minimum Age: 54 Months
Maximum Age: 88 Months

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Working memory training<br> | Behavioral: Cogmed Working memory training<br>* 15 minutes of working memory training, 5 days a week for a period of 5 weeks<br>|
| Sham Comparator: Control version of working memory training<br> | Behavioral: Control version of Cogmed working memory training<br>* 15 minutes of 'sham' working memory training, 5 days a week for a period of 5 weeks<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| ADHD criteria according to the DSM-IV-TR rated by the investigator |  | 7 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Neurocognitive performance and electrocortical activity |  | 7 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Attention deficit disorder with hyperactivity, Working memory training, Placebo, Behavioral symptoms, Neuropsychology, Electropsychophysiology