Erector Spinae Versus Paravertebral in Pediatric PCNL

Study Overview
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Brief Summary
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To compare the efficacy of ultrasound-guided erector spinae plane block versus ultrasound-guided paravertebral block in pediatric patients undergoing percutaneous nephrolithotomy

Detailed Description
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Percutaneous Nephrolithotomy (PCNL) is a commonly performed surgical procedure for complex upper renal tract calculi. Although the skin incision for PCNL appears small, the intensity of intraoperative and postoperative pain is significant owing to soft tissue injury. Erector spinae plane (ESP) block is an interfascial block that was first described by Forero et al. in 2016. It can be performed by injecting the local anesthetic in the deep interfascial plane of the erector spinae muscle to provide both visceral and somatic analgesia with a sensory level from T2-4 to L1-2. . Paravertebral block is the technique of injecting local anesthetics in a space immediately lateral to where the spinal nerves emerge from the intervertebral foramina. This technique is used increasingly for intra-operative and post-operative.

Official Title
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Ultrasound-guided Erector Spinae Plane Block Versus Ultrasound-guided Thoracic Paravertebral Block in Pediatric Patients Undergoing Percutaneous Nephrolithotomy

Conditions
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Renal Stone, Percutaneous, Nephrolithotomy

Intervention / Treatment
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* Procedure: Erector spinae plane block
* Procedure: Paravertebral block


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients undergoing percutaneous nephrolithotomy Exclusion Criteria: Coagulation disorders Infection at the site of injection Allergy to the local anesthetics used Spinal cord abnormalities or neurological deficits

Ages Eligible for Study
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Minimum Age: 2 Years
Maximum Age: 12 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Erector spinae plane block<br>Ultrasound-guided erector spinae plane block | Procedure: Erector spinae plane block<br>* Ultrasound-guided erector spinae plane block<br>|
| Experimental: Paravertebral<br>Ultrasound-guided thoracic paravertebral block | Procedure: Paravertebral block<br>* Ultrasound-guided paravertebral block<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Total consumption of paracetamol |  | The first 24 hours postoperatively | 
| Time to first rescue analgesia |  | The first 24 hours postoperatively | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The concentration of sevoflurane in percent |  | Through the surgery, an average of 2 hours | 
| Systolic, diastolic, and mean blood pressure during surgery in mmHg |  | Through the surgery, an average of 2 hours | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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paravertebral block, Erector spinae plane block, Percutaneous nephrolithotomy, pediatric