The Asian Transcatheter Aortic Valve Replacement Registry

Study Overview
=================
Brief Summary
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The purpose of this study is to evaluate the clinical outcomes of transcatheter aortic valve replacement (TAVR) in the Asian Pacific population

Detailed Description
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This registry changes to TP-TAVR registry(NCT03826264). Some subjects moved to TP-TAVR registry and continue to 10-year follow-up.

Official Title
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Evaluation of Clinical Outcomes of Transcatheter Aortic Valve Replacement in the Asian Pacific Population

Conditions
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Aortic Valve Stenosis, Aortic Diseases

Intervention / Treatment
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* Device: transcatheter aortic valve replacement


Participation Criteria
=================
Eligibility Criteria
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Inclusion Criteria: Patients with symptomatic severe aortic stenosis who are not candidates for surgical aortic valve replacement because of coexisting illnesses The patient or guardian agrees to the study protocol and the schedule of clinical follow-up, and provides informed, written consent, as approved by the appropriate Institutional Review Board/Ethics Committee of the respective clinical site
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
=================
How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Device: transcatheter aortic valve replacement|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Death |  | 1 month | 
| Death |  | 6 months | 
| Death |  | 1 year | 
| Death |  | 2 years | 
| Death |  | 3 years | 
| Death |  | 4 years | 
| Death |  | 5 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Death from cardiac cause |  | 1 month | 
| Death from cardiac cause |  | 6 months | 
| Death from cardiac cause |  | 1 year | 
| Death from cardiac cause |  | 2 years | 
| Death from cardiac cause |  | 3 years | 
| Death from cardiac cause |  | 4 years | 
| Death from cardiac cause |  | 5 years | 
| Stroke |  | 1 month | 
| Stroke |  | 6 months | 
| Stroke |  | 1 year | 
| Stroke |  | 2 years | 
| Stroke |  | 3 years | 
| Stroke |  | 4 years | 
| Stroke |  | 5 years | 
| Myocardial infarction |  | 1 month | 
| Myocardial infarction |  | 6 months | 
| Myocardial infarction |  | 1 year | 
| Myocardial infarction |  | 2 years | 
| Myocardial infarction |  | 3 years | 
| Myocardial infarction |  | 4 years | 
| Myocardial infarction |  | 5 years | 
| Repeat hospitalization |  | 1 month | 
| Repeat hospitalization |  | 6 months | 
| Repeat hospitalization |  | 1 year | 
| Repeat hospitalization |  | 2 years | 
| Repeat hospitalization |  | 3 years | 
| Repeat hospitalization |  | 4 years | 
| Repeat hospitalization |  | 5 years | 
| Acute kidney injury |  | 1 month | 
| Acute kidney injury |  | 6 months | 
| Acute kidney injury |  | 1 year | 
| Acute kidney injury |  | 2 years | 
| Acute kidney injury |  | 3 years | 
| Acute kidney injury |  | 4 years | 
| Acute kidney injury |  | 5 years | 
| Vascular complication |  | 1 month | 
| Vascular complication |  | 6 months | 
| Vascular complication |  | 1 year | 
| Vascular complication |  | 2 years | 
| Vascular complication |  | 3 years | 
| Vascular complication |  | 4 years | 
| Vascular complication |  | 5 years | 
| Bleeding events |  | 1 month | 
| Bleeding events |  | 6 months | 
| Bleeding events |  | 1 year | 
| Bleeding events |  | 2 years | 
| Bleeding events |  | 3 years | 
| Bleeding events |  | 4 years | 
| Bleeding events |  | 5 years | 
| Device success |  | 1 month | 
| Device success |  | 6 months | 
| Device success |  | 1 year | 
| Device success |  | 2 years | 
| Device success |  | 3 years | 
| Device success |  | 4 years | 
| Device success |  | 5 years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
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transcatheter aortic valve replacement, asian pacific, asian