Correlation Between Pulmonary Rehabilitation and TFC

Study Overview
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Brief Summary
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To study the effects of lung rehabilitation on the heart's hemodynamic performance of patients with chronic bidirectional lung disease when performing routine and regular PR, and found that the effects of lung rehabilitation on the heart mechanism and patients long-term quality of life research.

Detailed Description
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This study will be conducted in the Pulmonary Rehabilitation Treatment Room on the 6th floor of the Affiliated University Hospital. The acceptance conditions are: (1) treatment of chronic pulmonary obstructive pulmonary disease in the lung rehabilitation clinic, and (2) signing of the subject's consent; exclusion conditions: (1) tracheostomized patients, (2) patients who cannot perform conventional lung rehabilitation, (3) patients who use respirators at home. The study is a prospective observational study. It is expected to include a total of 25 subjects. The study will be implemented for one year from the date of IRB adoption. Before performing PR treatment, performed the 6th and 12th Every month, routine lung function, six-minute walking tests, and non-invasive cardiac output measurements are performed. The main results are: cardiac hemodynamic parameters.

Official Title
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Correlation Between Pulmonary Rehabilitation and Thoracic Fluid Capacity: One-year Follow-up of Observation Research

Conditions
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COPD Received PR

Intervention / Treatment
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* Procedure: pulmonary rehabilitation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: treatment of chronic pulmonary obstructive pulmonary disease in the lung rehabilitation clinic signing of the subject's consent Exclusion Criteria: gas-cut patients patients who cannot perform conventional lung rehabilitation patients who use respirators at home
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: pulmonary rehabilitation|one-year regular lung rehabilitation treatment and control the intensive monitoring of hemodynamic parameters|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| cardiac hemodynamic parameters | heart rate (HR) | one year | 
| cardiac hemodynamic parameters | blood pressure (BP) | one year | 
| cardiac hemodynamic parameters | stroke volume (SV) | one year | 
| cardiac hemodynamic parameters | cardiac output (CO) | one year | 
| cardiac hemodynamic parameters | total peripheral resistance (TPR) | one year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| mMRC (Modified Medical Research Council) Dyspnea Scale Dyspnea Scale | assessing the severity of breathlessness in patients with COPD | one year | 
| Chronic Respiratory Disease Questionnaire | The Chronic Respiratory Disease Questionnaire (CRQ) is the most commonly used disease specific measurement tool to assess health related quality of life (HRQL) in patients with chronic respiratory disease. It examines four aspects of patients' lives: dyspnoea, fatigue, emotional function, and mastery (the feeling of control over the disease and its effects). | one year | 
| COPD Assessment Test | measure the impact of COPD on a person's life, and how this changes over time. Patient-completed questionnaire assessing globally the impact of COPD (cough, sputum, dysnea, chest tighteness) on health status. Range of CAT scores from 0-40. Higher scores denote a more severe impact of COPD on a patient's life. | one year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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pulmonary rehabilitation, negative pressure ventilation, electrical cardiometry, chronic obstructive pulmonary disease