Prevalence and Associated Factors of Sarcopenia Among Elderly Patients in Osteoporosis Clinic

Study Overview
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Brief Summary
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This was a cross-sectional study. Patients who attended the osteoporosis clinic of Kowloon Hospital from June to December 2022 were recruited. Grip strength and appendicular skeletal muscle mass index were measured with a Jamar dynamometer and a bioimpedance analyser. Since most patients in our clinic are of Chinese ethnicity, the diagnostic criteria in the Consensus Update on Sarcopenia Diagnosis and Treatment by the Asian Working Group for Sarcopenia in 2019 was utilised. The diagnosis of sarcopenia was established by the presence of both low grip strength (Male: < 28 kg, Female < 18 kg) and low appendicular skeletal mass (Male: < 7.0 kg/m2, Female: < 5.7 kg/m2)

Official Title
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Prevalence and Associated Factors of Sarcopenia Among Elderly Patients in Osteoporosis Clinic

Conditions
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Sarcopenia, Osteoporosis

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients aged 60 years old or above Diagnosed with osteoporosis by: Fragility fracture or T-score ≤-2.5 SDs at any site on DXA scan and; Able to read and write Chinese Exclusion Criteria: Unable to maintain standing posture for bioimpedance analysis Modified Functional Ambulation Classification (MFAC) ≤ IV Incompetent in giving consent Unable to follow instructions Implanted with metal in any of four limbs Implanted with pacemaker, implantable cardioverter defibrillator or any other types of electrical device

Ages Eligible for Study
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Minimum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prevalence of Sarcopenia | The diagnosis of sarcopenia would be established by the co-existence of low grip strength and low appendicular skeletal muscle mass. | June - December 2022 | 
| Grip strength | Grip strength would be measured with Jamar digital dynamometer. | June - December 2022 | 
| Appendicular Skeletal Muscle Mass Index | Appendicular Skeletal Muscle Mass Index would be measured with bioimpedance analyzer. | June - December 2022 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Association between BMI and Sarcopenia. | BMI would be measured on clinic attendance. | June - December 2022 | 
| Association between Frailty and Sarcopenia. | Clinical Frailty Scale would be documented in clinical consultation. | June - December 2022 | 
| Association between Charlson Comorbidities Index and Sarcopenia | Components of Charlson Comorbidities Index would be extracted from medical record. | June - December 2022 | 
| Association between Bone Mineral Densities and Sarcopenia | Bone mineral densities of spine and neck of femur would be extracted from the report of dual-energy X-ray absorptiometry. | June - December 2022 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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osteosarcopenia, sarcopenia, osteoporosis, geriatric medicine