Changing Habits in Anorexia Nervosa: Novel Treatment Development

Study Overview
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Brief Summary
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The investigators are examining what types of psychotherapy are most helpful for patients as they undergo weight restoration treatment for anorexia nervosa. In this study, patients who are receiving care on our inpatient unit will also receive 4 weeks of one two types of psychotherapy: Supportive Psychotherapy or Regulation Emotions and Changing Habits.

Detailed Description
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Patients will be receiving specialized inpatient treatment for anorexia nervosa on the Eating Disorders Unit at the New York State Psychiatric Institute, where care is provided free of charge. Study procedures will begin after one week of acclimating to the inpatient unit. Patients will be randomly assigned to receive either Supportive Psychotherapy (focused on the transition to the inpatient unit) or REACH (focused on changing routines or habits that have become part of the eating disorder). Each treatment consists of 12-sessions, delivered 2-3 times per week. Before and after treatment, patients will be asked to participate in interviews, questionnaires, and a lunch meal.

Official Title
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Changing Habits in Anorexia Nervosa

Conditions
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Anorexia Nervosa

Intervention / Treatment
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* Behavioral: REACH
* Behavioral: Supportive Psychotherapy
* Behavioral: Inpatient Behavioral Treatment


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: DSM5 diagnosis of anorexia nervosa Age>= 18 Medically stable Able to provide informed consent Exclusion Criteria: Other psychiatric disorder requiring acute treatment Serious medical illness Antipsychotic medication Severe cognitive impairment

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: REACH<br>Psychotherapy | Behavioral: REACH<br>* REACH is a 12-session intervention, delivered 2-3 times per week for 45 minutes. The treatment focuses on identifying and changing behaviors and routines that have become entrenched and help perpetuate the illness.<br>Behavioral: Inpatient Behavioral Treatment<br>* Inpatient treatment at the NYSPI is a behaviorally-based treatment program for anorexia nervosa. This is a non-research, clinical intervention for individuals with anorexia nervosa.<br>|
| Active Comparator: Supportive Psychotherapy<br>Psychotherapy | Behavioral: Supportive Psychotherapy<br>* The Supportive Psychotherapy is based on the Specialist Supportive Care (McIntosh et al, 2005), and modified for the current research procedures. Supportive Psychotherapy is a 12-session intervention, delivered 2-3 times per week as 45 minute sessions, focusing on symptoms of anorexia nervosa during the transition to the inpatient unit.<br>Behavioral: Inpatient Behavioral Treatment<br>* Inpatient treatment at the NYSPI is a behaviorally-based treatment program for anorexia nervosa. This is a non-research, clinical intervention for individuals with anorexia nervosa.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Habit strength as measured by self report scales |  | 4 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Eating behavior as measured by laboratory meal |  | 4 weeks | 
| Eating behavior as measured by meal observation |  | 4 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Eating Disorders, Psychotherapy, Anorexia Nervosa, Treatment