Nasopharyngeal Airway Guide Nasogastric Tube Placement

Study Overview
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Brief Summary
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Nasogastric tube placement is essential for various surgery and critically ill patients. However, NG tube insertion in anesthetized, paralyzed, and intubated or unconscious patients may be difficult, with reported success rate less 50% on the first attempt without any auxiliary devices. Endotracheal tube intubation narrow the space of oropharynx and hypopharynx. Loss ability to swallow and tongue drop also made the NG tube coil in the mouth easily. Investigators assume nasopharyngeal airway can facilitate NG tube insertion by opening a channel from nostril to epiglottis and reduce complications by protecting nasal cavity while inserting NG.

Official Title
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A Nasopharyngeal Airway Facilitates Nasogastric Intubation in Anesthetized Intubated Patients: A Randomized Controlled Trial

Conditions
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Nasogastric Tube, Nasopharyngeal Airway, Anesthesia, General

Intervention / Treatment
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* Procedure: With nasopharyngeal airway
* Procedure: Without nasopharyngeal airway


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patient should be > 20 years old, ASA 1 3 under going schedule general anesthesia with endotracheal tube intubation Patient who required NG tube placement for perioperative care Exclusion Criteria: Coagulation abnormality (PLT≤100000, INR>1.2 & PT≥13) Hemodynamic unstable (with inotropic agent use) Arrythmia Esophageal varices or stricture, Esophageal cancer, trauma or previous esophageal surgery Gastric cancer involve cardiac orifice Corrosive chemical (strong acid or alkali) ingestion Skull base fracture Recent nasal surgery, nasal fracture or severe nasal obstruction Loose teeth that make endotracheal tube can not fix right side

Ages Eligible for Study
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Minimum Age: 20 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: NG tube placement with nasopharyngeal tube<br> | Procedure: With nasopharyngeal airway<br>* Nasopharyngeal airway is previously inserted into selected nostril. NG tube is properly lubricated and placed through Nasopharyngeal airway.<br>|
| Active Comparator: NG tube placement without nasopharyngeal tube<br> | Procedure: Without nasopharyngeal airway<br>* NG tube is properly lubricated and placed into selected nostril<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| First attempt successful rate | with or without Nasopharyngeal airway assistance | can be know after NG tube placement immediately | 
| Second attempt successful rate | with or without Nasopharyngeal airway assistance | can be know after NG tube placement immediately | 
| Overall successful rate insertion | with or without Nasopharyngeal airway assistance | can be know after NG tube placement immediately | 
| Time cost during NG tube placement | with or without Nasopharyngeal airway assistance | can be know after NG tube placement immediately | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of NG tube coiling | with or without Nasopharyngeal airway assistance during NG tube insertion | can be know after NG tube placement immediately | 
| Incidence of NG tube kinking | with or without Nasopharyngeal airway assistance during NG tube insertion | can be know after NG tube placement immediately | 
| Incidence of NG tube knotting | with or without Nasopharyngeal airway assistance during NG tube insertion | can be know after NG tube placement immediately | 
| Incidence of epistaxis after NG tube placement | with or without Nasopharyngeal airway assistance during NG tube insertion | can be know after NG tube placement immediately | 
| Mean blood pressure change after NG tube placement | with or without Nasopharyngeal airway assistance | can be know after NG tube placement immediately | 
| Heart rate change after NG tube placement | with or without Nasopharyngeal airway assistance | can be know after NG tube placement immediately |