Evaluation of Enteral Nutrition in Critically Ill Children

Study Overview
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Brief Summary
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The aim of this study was to evaluate the effect of calorie and enteral feeding timing on survival in critically ill children receiving inotropic, vasopressor and inodilatory supplements.

Detailed Description
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The aim of this study was to evaluate the effect of calorie and enteral feeding timing on survival in critically ill children receiving inotropic, vasopressor and inodilatory supplements. Early enteral nutrition will be initiated within the first 24 hours of hospitalization in critically ill children who have inotropic vasopressor and inodilator support without any problems and contraindications in gastrointestinal system functions. The energy requirement of the intubated patients will be measured by indirect calorie meter method. Schofield method will be used to calculate the daily energy needs of extubated patients. 30% of the targeted energy in the first 48 hours of hospitalization and 80% of the targeted energy in the first week will be achieved by enteral nutrition.Nutritional solutions with a concentrated formula of 1 / 1.5 will be given to patients with cardiac pulmonary or renal disease requiring fluid restriction.Patients will be followed up for vomiting, diarrhea, abdominal distention, feeding intolerance, gastric residues and gastrointestinal bleeding. If these findings develop, the patient's nutrition will be interrupted according to the clinician's assessment and enteral nutrition will be re-fed as soon as possible.

Official Title
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Evaluation of Enteral Nutrition in Critically Ill Children Receiving Inotropic Support in Pediatric Intensive Care Unit

Conditions
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Critical Illness, Enteral Feeding Intolerance

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Children with normal gastrointestinal system function Children receiving inotropic, vasopressor or inodilatory support Exclusion Criteria: Children with gastrointestinal system dysfunction Children with enteral nutrition contraindicated Children with metabolic disease with special nutrition

Ages Eligible for Study
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Minimum Age: 1 Month
Maximum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 28-d mortality | To evaluate the effect of enteral feeding timing on survival | 28 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Lactate | To observe safe lactate levels suitable for enteral nutrition. Lactate levels will be measure 4 times in a day. | During inotropic treatment | 
| Vasoactive inotrope score | To observe maximum vasoactive inotrope score suitable for enteral nutrition. Maximum VIS will be recorded. | During inotropic treatment | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Enteral feeding, vasopressor, lactate