Nursing Fro Laparoscopic vs. Open Hepatectomy

Study Overview
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Brief Summary
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This study was divided into laparoscopic hepatectomy (observation group) and laparoscopic hepatectomy (control group).Compared two groups of age, sex, body mass index (BMI), tumor diameter, number of tumors (single/multiple), pathologic characteristics, HBsAg (positive/negative), liver function, AFP, Child - Pugh, grading, nursing method and comparison of two groups of patients after surgery (surgical incision length, intraoperative blood, intraoperative blood transfusion and transfusion volume, operation time) the number of cases of and postoperative rehabilitation (death cases, for the first time the meal time, anus exhaust time, analgesic bed, first time, the abdominal cavity drainage tube time, length of hospital stay, postoperative days and liver function index.Follow-up: the survival rates of the two groups were compared in six months, one year, two years, three years and five years.In this study, the initial selection of the minimum sample size of 30 cases, plus 20% inefficiencies, the final initial selection of 36 cases, and the later expansion of the sample size of 100 cases.The research date starts on October 1, 2017.

Detailed Description
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Research design and methods: This study was divided into laparoscopic hepatectomy (observation group) and laparoscopic hepatectomy (control group).Compared two groups of age, sex, body mass index (BMI), tumor diameter, number of tumors (single/multiple), pathologic characteristics, HBsAg (positive/negative), liver function, AFP, Child - Pugh, grading, nursing method and comparison of two groups of patients after surgery (surgical incision length, intraoperative blood, intraoperative blood transfusion and transfusion volume, operation time) the number of cases of and postoperative rehabilitation (death cases, for the first time the meal time, anus exhaust time, analgesic bed, first time, the abdominal cavity drainage tube time, length of hospital stay, postoperative days and liver function index.Follow-up: the survival rates of the two groups were compared in six months, one year, two years, three years and five years.In this study, the initial selection of the minimum sample size of 30 cases, plus 20% inefficiencies, the final initial selection of 36 cases, and the later expansion of the sample size of 100 cases. Statistical methods: by means of SPSS 23.0 to analyze the data, all data after the normal test to choose the appropriate statistical methods, the normal distribution of measurement data in the two groups use surgery and postoperative recovery using two sets of samples t test, liver function index using analysis of variance, non-normal distribution using nonparametric test, count data chi-square test, P < 0.05 for the difference was statistically significant.Survival analysis was performed on two groups of patients.The research date starts on October 1, 2017.

Official Title
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Comparison of Efficacy and Nursing Between Laparoscopic Hepatectomy and Open Hepatectomy for Primary Liver Cancer

Conditions
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Liver Cancer, Liver Neoplasms

Intervention / Treatment
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* Procedure: lpaparoscopic hepatectomy
* Procedure: open hepatectomy


Participation Criteria
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Eligibility Criteria
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Inclusion criteria: Hepatocellular carcinoma There was no distant metastasis in patients with malignant tumors. Exclusion criteria: primary tumor diameter > 10cm Thrombosis of portal or inferior vena cava carcinoma Severe organic disease or cirrhosis of the liver Laparoscopic transposition of the abdomen Concomitant coagulant function abnormal patient.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| laparoscopic hepatectomy<br>laparoscopic hepatectomy for primary liver cancer | Procedure: lpaparoscopic hepatectomy<br>* laparoscopic hepatectomy： laparoscopic hepatectomy for hepatocellular carcinoma.<br>|
| open hepatectomy<br>open hepatectomy for primary liver cancer | Procedure: open hepatectomy<br>* open hepatectomy: open hepatectomy for hepatocellular carcinoma<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The incidence of complications of primary liver cancer treated by laparoscopic hepatectomy and laparoscopic hepatectomy,The questionnaire survey | The incidence of complications, in percent | Patients with hepatocellular carcinoma who were hospitalized together on October 1, 2017 were studied at the time point before discharge. | 
| The survival rate of primary liver cancer treated by laparoscopic hepatectomy and laparoscopic hepatectomy,Telephone pays a return visit | Survival rate, percent | 1 month after discharge | 
| The survival rate of primary liver cancer treated by laparoscopic hepatectomy and laparoscopic hepatectomy,Telephone pays a return visit | Survival rate, percent | 3 month after discharge | 
| The survival rate of primary liver cancer treated by laparoscopic hepatectomy and laparoscopic hepatectomy,Telephone pays a return visit | Survival rate, percent | 6 month after discharge | 
| The survival rate of primary liver cancer treated by laparoscopic hepatectomy and laparoscopic hepatectomy,Telephone pays a return visit | Survival rate, percent | 1 year after discharge | 
| The survival rate of primary liver cancer treated by laparoscopic hepatectomy and laparoscopic hepatectomy,Telephone pays a return visit | Death and recurrence | 2 year after discharge | 
| The survival rate of primary liver cancer treated by laparoscopic hepatectomy and laparoscopic hepatectomy,Telephone pays a return visit | Death and recurrence | 3 year after discharge | 
| The survival rate of primary liver cancer treated by laparoscopic hepatectomy and laparoscopic hepatectomy,Telephone pays a return visit | Survival rate, percent | 5 year after discharge | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Comparison of oxygen uptake days between laparoscopic hepatectomy and laparoscopic hepatectomy for primary liver cancer, unit: day | Oxygen uptake days, per day | Patients with liver cancer who are hospitalized on 1 October 2017 will be included in the study date.The study time is 1 year. | 
| Comparison of ecg monitoring days between laparoscopic hepatectomy and laparoscopic hepatectomy for primary liver cancer Unit: day | Guardianship days, unit: days | Patients with liver cancer who are hospitalized on 1 October 2017 will be included in the study date.The study time is 1 year. | 
| Comparison of the number of replacement drainage bags for primary hepatocellular carcinoma between laparoscopic hepatectomy and laparoscopic hepatectomy, unit: number | Compare the number of times to replace the drainage bag, unit: number | Patients with liver cancer who are hospitalized on 1 October 2017 will be included in the study date.The study time is 1 year. | 
| Comparison of infusion days between laparoscopic hepatectomy and laparoscopic hepatectomy for primary liver cancer Unit: day | Infusion days, unit: days | Patients with liver cancer who are hospitalized on 1 October 2017 will be included in the study date.The study time is 1 year. | 
| Comparison of muscle injection times between laparoscopic hepatectomy and laparoscopic hepatectomy in primary liver cancer: times | Muscle injections,Unit: times | Patients with liver cancer who are hospitalized on 1 October 2017 will be included in the study date.The study time is 1 year. | 
| Comparison between laparoscopic hepatectomy and laparoscopic hepatectomy in primary hepatocellular carcinoma Unit: times | Number of subcutaneous injections Unit: times | Patients with liver cancer who are hospitalized on 1 October 2017 will be included in the study date.The study time is 1 year. | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Liver Cancer, laparoscopic hepatectomy, open hepatectomy