The Diagnosis and Treatment System of Transesophageal Echocardiography in ICU

Study Overview
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Brief Summary
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Transesophageal ultrasound offers imaging through the esophagus on the surface of the heart, with good image quality and unique advantages. However, no studies to date have examined its effect in critically ill patients in China.Therefore, the investigators aimed to compare the efficacy and safety of TEE with TTE. the investigators will conducte a Multi-center, prospective observational control study enrolling critically ill adult patients in several ICU in China .

Detailed Description
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Patients in ICU were assessed for the need for TEE by trained researcher. Eligible patients would be conducted tee examination by researcher A, TTE by the researcher B ,at the same time, researcher C records the basic condition and clinical data of patientsand carried out micro-enlargement test.The examination results are judged by A and B respectively and provided to the physician of this patient, and A return visit to the physician wold be conducted by researcher D to evaluate the acceptance of TTE and TEE results and judge the clinical effects. The primary outcome is the clinical effects.

Official Title
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The Diagnosis and Treatment System of Transesophageal Echocardiography in ICU

Conditions
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Critically Ill

Intervention / Treatment
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* Diagnostic Test: Transesophageal echocardiography


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: The quality of Transthoracic echocardiography is poor ( >3 sections cannot be obtained or the inner membrane is not clear) The diagnosis of the etiology by Transthoracic ultrasonography is still unclear The results of Transthoracic ultrasonography are inconsistent with clinical judgment or cannot explain the existing signs. No obvious improvement or even aggravation after thoracic examination and corresponding treatment Special conditions or clinical scenarios Other clinicians think a TEE check is required. Exclusion Criteria: There is a tee test taboo and clinicians evaluate the risk over benefit Did not sign an informed consent form

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Screening
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: TEE group<br>Eligible patients would be conducted TEE examination by researcher A,The examination results are judged by A and provided to the physician of this patient, | Diagnostic Test: Transesophageal echocardiography<br>* Eligible patients would be conducted both Transesophageal echocardiography and Transthoracic echocardiography to offer independent results<br>* Other names: Transthoracic echocardiography;|
| Active Comparator: TTE group<br>Eligible patients would be conducted TTE examination by researcher B,The examination results are judged by B and provided to the physician of this patient, | Diagnostic Test: Transesophageal echocardiography<br>* Eligible patients would be conducted both Transesophageal echocardiography and Transthoracic echocardiography to offer independent results<br>* Other names: Transthoracic echocardiography;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Conclusion of the adoption | Researcher C conducted a questionnaire survey on attending physician to evaluate the effect | 48 hours after completion of the examination | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| adverse events | Adverse events associated with the examination，eg.1.Anesthetic allergy;2.Nausea, vomiting, choking cough or aspiration;3.Laryngeal edema and even asphyxiation;4.Severe arrhythmia;5.Esophageal perforation, bleeding, or local hematoma;6.Other accidental deaths, such as acute myocardial infarction, shock, haemorrhage and possibly even death;7.Other unpredictable contingencies or complications | completion of the examination | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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transesophageal echocardiography, intensive care unit