Effect of Skate Skin Extract on Body Fat in Overweight Adults

Study Overview
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Brief Summary
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Comparison of a randomized, double-blind, and control-group study for the effect of oral ingestion of low-molecular collagen peptides derived from Skate Skin on body fat reduction in adults

Detailed Description
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Our aim is to investigate the effect of oral ingestion of low-molecular collagen peptides derived from Skate Skin on body fat reduction in adults by a randomized, double-blind, and control-group study.

Official Title
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Effect of Skate Skin Extract on Body Fat in Overweight Adults: A RCT

Conditions
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Body Fat

Intervention / Treatment
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* Dietary Supplement: Skate Skin group
* Dietary Supplement: Control group


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: BMI 23 30 kg/m2 Exclusion Criteria: Within the last 6 months, severe cerebrovascular disease (cerebral infarction, cerebral hemorrhage, etc.), heart disease(Angina pectoris, myocardial infarction, heart failure, arrhythmia requiring treatment), or malignant diseases (however, although subjects have a history of cerebrovascular disease and heart disease, they can be included if their status are clinically stable) Patients with uncontrolled hypertension (blood pressure greater than 160/100 mmHg) Diabetic patients with poor glycemic control with a fasting blood glucose of 160 mg/dl or more Those who are treated with hypothyroidism or hyperthyroidism Creatinine levels: more than twice the normal upper limit AST (GOT) or ALT (GPT) levels: more than twice the normal upper limit Those complaining of severe gastrointestinal symptoms such as heartburn and indigestion Drugs that affect weight within the last month (absorption inhibitors and Appetite suppressant, health food / supplements related to obesity improvement, psychiatric Drugs, beta blockers, diuretics, birth control pills, steroids, female hormones) If you are taking Participated in the commercial obesity program within the last 3 months. If you have participated or are planning to participate in another clinical trial within the past month If yes Alcohol abuser Smoking abstinence within 3 months If they are pregnant or lactating or have a pregnancy plan during the clinical trial Those with allergic reactions to the constituent food Any person deemed inappropriate by the researcher for other reasons

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Skate Skin group<br>2,000 mg of low-molecular collagen peptide was orally administered per day for 12 weeks. | Dietary Supplement: Skate Skin group<br>* 2,000 mg of low-molecular collagen peptide was orally administered per day for 12 weeks.<br>|
| Placebo Comparator: Control group<br>2,000 mg of placebo was orally administered per day for 12 weeks. | Dietary Supplement: Control group<br>* 2,000 mg of starch was orally administered per day for 12 weeks.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Body fat percent | Measured by DEXA | Change from baseline body fat percent at 6, 12 weeks |