The Prevalence and Characteristics of Adrenal Incidentaloma

Study Overview
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Brief Summary
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To investige the prevalence, characteristics and prognosis of adrenal incidentalomas in Chinese adults.

Detailed Description
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With the development of imaging detection technology and its wide application in clinic, the detection rate of adrenal incidentaloma (AI) has been greatly improved. Most AI are benign and do not have the function of autonomic hormone secretion, but about 20% of them have function and can secrete adrenal hormone autonomously. Studies based on biopsy reports show that the prevalence of AI is about 2%, and the prevalence of AI detected by CT scan is 1% - 4.5%. However, most of these studies are retrospective, and there may be selection bias and other confounding factors. There is no large sample prospective study on the prevalence of AI in the general population. The purpose of this study is to prospectively include patients with adrenal incidentaloma in community physical examination population, and evaluate their function and prognosis. The research results will provide new evidence for standardized diagnosis and treatment of adrenal incidentaloma in the future.

Official Title
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The Prevalence and Characteristics of Adrenal Incidentaloma: A Prospective Study

Conditions
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Prevalence, Adrenal Incidentaloma

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: ·On weekdays, the first 100 individuals, aged 18 to 78 years, taking health checkup in the Community Health Examination Center were invited to take part in the study. Exclusion Criteria: with known adrenal diseases; with continuous steroids or drug treatment that might influence cortisol secretion ordexamethasone metabolism and could not be stopped refuse to participate in the study.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 78 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| adrenal incidentalomas in Chinese community adults<br>On weekdays, the first 100 individuals, aged 18 to 78 years, taking health checkup in the Community Health Examination Center were invited to take part in the study. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prevalence and Characteristics of Adrenal Incidentaloma | To investigate the prevalence and characteristics of Adrenal Incidentaloma in general population in China | 1 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Steroid hormones in the function of Adrenal Incidentaloma | prospectively evaluate potential predictive role of combined detection of multiple steroid hormones in the function of Adrenal Incidentaloma | 1 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Prevalence, characteristics, adrenal incidentaloma