Early Strength Training After Hip Fracture Surgery

Study Overview
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Brief Summary
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Patients treated surgically for a hip fracture have a need of rehabilitation for the regain of former functional skills. Despite an optimized fast track in-hospital rehabilitation program it has been found that patients with hip fracture within 2 weeks after the hip fracture loose more than half of their muscle strength in the fractured limb compared to non-fractured limb. New studies including patients with total hip arthroplasty and strength training applied early after surgery has shown promising results regarding prevention of loss of muscle strength. No similar study has been found including patients with hip fracture. The purpose of this study is to examine the feasibility of progressive knee-extension strength training of the hip fractured limb, starting Day 1 after surgical treatment for a hip fracture and proceeded every weekday during their hospital stay. The study will include 20 patients surgically treated for a cervical hip fracture and 20 patients surgically treated for an intertrochanteric or subtrochanteric fracture. All patients are admitted from their own home. Age 60 years or older.

Detailed Description
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Kronborg L, Bandholm T, Palm H, Kehlet H, Kristensen MT (2014) Feasibility of Progressive Strength Training Implemented in the Acute Ward after Hip Fracture Surgery. PLoS ONE 9(4): e93332. doi:10.1371/journal.pone.0093332

Official Title
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Feasibility of Progressive Strength Training in the Early Post Surgical Rehabilitation Period After Hip Fracture Surgery

Conditions
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Hip Fractures

Intervention / Treatment
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* Other: Knee-extension strength training of the fractured limb


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Hip fracture diagnosed patients age ≥60 years, admitted to the acute hip fracture unit. Medial femoral neck fracture, pertrochanteric fracture or subtrochanteric fracture. Ability to speak and understand the Danish language. Cognitively well-preserved and able to give personal informed consent no later than by 5th post surgical day. Home-residing and with an independent pre-fracture ability to walk equal to New Mobility Score at ≥ 2 indoor. Exclusion Criteria: Multiple fractures Postsurgical restrictions of mobilization Patient not accepting participation in relevant exercise therapy Fracture caused by cancer metastases Terminal illness Neurological impairment e.g. hemi paresis.

Ages Eligible for Study
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Minimum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Strength training, fractured limb<br>Knee-extension strength training of the fractured limb: Daily knee-extension strength training with 3 x 10 repetitions using an intensity of 10 Repetition Maximum (RM) for the hip fractured limb started as soon as possible after surgery. | Other: Knee-extension strength training of the fractured limb<br>* Daily knee-extension strength training with 3 x 10 repetitions using an intensity of 10 Repetition Maximum (RM) for the hip fractured limb started as soon as possible after surgery.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Feasibility of progression in training loads (kg) during daily knee-extension strength training when commenced immediately after hip fracture surgery. | Feasibility is evaluated on the basis of adherence to program, adverse events, target training intensity, hip pain during training and other potential restricting factors, e.g. confusion, exhaustion and dropouts. | Baseline to discharge, in average 10 days. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in maximum isometric knee-extension strength and strength deficits, fractured % of non-fractured limb measured by handheld dynamometer. |  | Baseline to discharge, in average 10 days. | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Hip fractures, Strength training