Quantitative Sensory Testing in Subjects With Sensitive Skin or Not

Study Overview
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Brief Summary
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Sensitive skin is a common problem, with 50% of women and 30% of men in Europe feel they have sensitive skin. The Quantitative sensory testing (QST) is a physico-psychic method that uses gradients stimuli of different modalities to measure a subjective somatosensory response. This allows to characterize sensory dysfunction by assessing the participation of small and large nerve fibers. The aim of this project is to characterize the presence or absence of a neurological disorder in patients with sensitive skin. This discovery would be a decisive argument to reinforce the suspicion that sensitive skins is linked to a small fiber neuropathy.

Detailed Description
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Sensitive skin is a common problem, with 50% of women and 30% of men in Europe feel they have sensitive skin. A sensitive skin is characterized by the occurrence of tingling sensations, tightness, heat, burning, itching or pain triggered by non pathogenic factors such as wind, heat, cold, water , cosmetics, toiletries, stress... The Quantitative sensory testing (QST) is a physico-psychic method that uses gradients stimuli of different modalities to measure a subjective somatosensory response. This allows to characterize sensory dysfunction by assessing the participation of small and large nerve fibers. The aim of this project is to characterize the presence or absence of a neurological disorder in patients with sensitive skin. This discovery would be a decisive argument to reinforce the suspicion that sensitive skins is linked to a small fiber neuropathy.

Official Title
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Quantitative Sensory Testing in Subjects With Sensitive Skin or Not

Conditions
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Sensitive Skin

Intervention / Treatment
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* Device: Quantitative Sensory Testing


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age: between 20 and 60 years Cooperating patient Informed and written consent of the subject Affiliated to the social security For subjects with sensitive skin: subjects with a score greater than 50 on the scale sensitive scale - To control subjects: subjects with result of less than 20 sensitive to the scale scale Exclusion Criteria: Adults subject with legal protection Subject in a social institution. Subject with major cognitive or psychiatric disorders Subject with pathological use of alcohol or consumption of another drug. Subject with skin involvement of the back of the dominant hand or malformation. Known sensitive neuropathy Pregnant woman Subject receiving medical treatment which may interfere with the results. Subject with treatment in the back of the dominant hand.

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Subjects with sensitive skin<br>Subjects with a score greater than 50 on the sensitive scale | Device: Quantitative Sensory Testing<br>* Study of detection thresholds of vibration, cold and pain related to the heat in the dominant hand of the subjects through the QST.<br>|
| Other: Subjects without sensitive skin<br>Subjects with result lower than 20 on the sensitive scale | Device: Quantitative Sensory Testing<br>* Study of detection thresholds of vibration, cold and pain related to the heat in the dominant hand of the subjects through the QST.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cutaneous perception threshold | The cutaneous perception threshold of pain to heat. | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The cutaneous perception threshold of vibration | The cutaneous perception threshold of pain to harm. | 6 months | 
| The cutaneous perception threshold of cold | The cutaneous perception threshold of cold | 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Sensitive skin, Quantitative Sensory Testing