Consequences of Post Stroke Polysomnographic Abnormalities on Functionnal Recovery and Survival After an Ischemic Stroke

Study Overview
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Brief Summary
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Ischemic stroke is a major public health issue, likely to cause functional disability. It is well known that sleep has an impact on brain plasticity, and after an ischemic stroke, studies have shown subjective sleep quality alterations and sleep architecture abnormalities. Furthermore, there is no clear guideline showing the usefulness of a systematic sleep investigation following an ischemic stroke. The aim of the study is to identify retrospectively correlation between polysomnographic abnormalities (sleep apnea, periodic limb movements, disturbed sleep architecture…) and functional recovery after an ischemic stroke. The study also assesses the impact of sleep abnormalities on survival, and the risk of new cardiovascular event.

Detailed Description
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This study is a retrospective observational study, from a cohort of patients who had a sleep recording (polysomnography or ventilatory polygraphy performed in Montpellier University Hospital) following an ischemic stroke.

Official Title
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Consequences of Post Stroke Polysomnographic Abnormalities on Functionnal Recovery and Survival After an Ischemic Stroke

Conditions
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Ischemic Stroke, Cerebral Infarct, Sleep Apnea, Periodic Limb Movement Disorder

Intervention / Treatment
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* Other: Sleep recording (already done)


Participation Criteria
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Eligibility Criteria
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Inclusion criteria: men and women, more than 18 years old medical history of ischemic stroke who had a sleep recording following the stroke Exclusion criteria: others types of strokes (bleeding, transient ischemic attack, cerebal veinous thrombosis) patients less than 18 years old

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 100 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| patients with a sleep recording performed<br>patients with a sleep recording performed in the sleep unit in Montpellier University Hospital, who had an ischemic stroke before the recording. | Other: Sleep recording (already done)<br>* Sleep recording (already done)<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Correlation between polysomnographic abnormalities and functional recovery | polysomnographic abnormalities : sleep apnea, periodic limb movements, distribution of sleep stage / functional recovery : modified rankin score and National Institutes of Health Stroke Scale at 6 months | functional recovery at 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Correlation between polysomnographic abnormalities and survival, onset of new cardio vascular events, functionnal recovery and quality of life. | polysomnographic abnormalities : sleep apnea, periodic limb movements, distribution of sleep stage / survival or onset of cardio vascular events, quality of life (SF 36), modified rankin score and National Institutes of Health Stroke Scale at one year. | survival or onset of new cardio vascular events at one year, quality of life evaluated by self questionnaire at one year and functionnal recovery (modified rankin score and National Institutes of Health Stroke Scale) at one year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Functional recovery, Ischemic stroke / cerebral infarct, Sleep, Polysomnography