The Effect of Pulmonary Rehabilitation on Bronchoscopic Volume Reduction Process Success

Study Overview
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Brief Summary
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The data of patients undergoing bronchoscopic volume reduction procedure will be analyzed retrospectively. Patients will be divided into two groups as patients with and without Pulmonary Rehabilitation before the procedure, and changes in functional levels of patients will be compared.

Detailed Description
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The data of patients who underwent bronchoscopic volume reduction between January 2013 and March 2019 will be examined. Patients will be divided into two groups as pulmonary rehabilitation applied (PR group) and not applied (Control group) before the procedure. Changes in the parameters of initial and rehabilitation follow-up will be examined.

Official Title
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The Effect of Pulmonary Rehabilitation on Bronchoscopic Volume Reduction Process Success

Conditions
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Emphysema, Pulmonary Rehabilitation, Bronchoscopic Lung Volume Reduction

Intervention / Treatment
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* Other: Pulmonary Rehabilitation
* Other: Standart care


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Between the ages of 18-75 Patients with a diagnosis of emphysema and bronchoscopic procedures Exclusion Criteria: • Patients who develop complications related to the procedure after bronchoscopic procedure.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Pulmonary Rehabilitation Group<br>Optimal medication and clinical follow-up plus Pulmonary rehabiltation | Other: Pulmonary Rehabilitation<br>* Exercise training+ Optimal medication and clinical follow-up<br>Other: Standart care<br>* Optimal medication and clinical follow-up<br>|
| Active Comparator: Non-Pulmonary Rehabilitation Group<br>Optimal medication and clinical follow-up | Other: Standart care<br>* Optimal medication and clinical follow-up<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Six minute walking test | The test was conducted in a 30-meter corridor in line with American Thoracic Society (ATS) guidelines. Patients were asked to walk as far as they can. Prior to and following the test, oxygen saturation, heart rate and Borg fatigue rating were measured, and the walking distance were recorded | 20 minutes | 
| Pulmonary Function Tests | PFTs were performed by using the Sensormedics model 2400 (Yorba Linda, CA, USA) spirometry device, and according to the American Thoracic Society (ATS) guidelines | 15 minutes | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Carbonmonoxide diffusion test | It will performed in the pulmonary function test laboratory using Cosmed Quark PFT (USA) with single-breath technique | 15 minutes |