Study of Visual-spatial Attention by Eye Tracking as a Function of Central or Peripheral Visual Impairment

Study Overview
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Brief Summary
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The objective of this pilot work is to determine the role of central and peripheral visions in explicit attention processes (saccade planning) in the case of visual impairment.

Official Title
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Study of Visual-spatial Attention by Oculomotor Recording (Eye Tracking) as a Function of Central or Peripheral Visual Impairment

Conditions
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Central or Peripheral Visual Impairment

Intervention / Treatment
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* Procedure: microperimetry
* Procedure: visual acuity
* Procedure: automated visual field
* Procedure: eye movements recording


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Male or female ≥18 years; Patient with a central visual deficit (central scotoma on the visual field: DMLA, cones dystrophy ...) or peripheral (annular scotoma: chronic glaucoma, retinitis pigmentosa ...) or without visual deficit (corrected visual acuity and visual field) Patient agreeing to participate in the study and signing informed consent Patient affiliated to social security Exclusion Criteria: Pregnant woman Patient with known epilepsy Major under judicial safeguard, or deprived of liberty Major under guardianship or curatorship or admitted to a health or social institution for purposes other than research.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: central vision disorder<br> | Procedure: microperimetry<br>* define the retinal fixation point and the differential sensitivity threshold of the retina.<br>Procedure: visual acuity<br>* using ETDRS scales<br>Procedure: automated visual field<br>* recording visual attention based on central or peripheral visual information<br>Procedure: eye movements recording<br>* recording of explicit visual attention based on central or peripheral visual information<br>|
| Experimental: peripheral vision disorder<br> | Procedure: microperimetry<br>* define the retinal fixation point and the differential sensitivity threshold of the retina.<br>Procedure: visual acuity<br>* using ETDRS scales<br>Procedure: automated visual field<br>* recording visual attention based on central or peripheral visual information<br>Procedure: eye movements recording<br>* recording of explicit visual attention based on central or peripheral visual information<br>|
| Other: control<br> | Procedure: microperimetry<br>* define the retinal fixation point and the differential sensitivity threshold of the retina.<br>Procedure: visual acuity<br>* using ETDRS scales<br>Procedure: automated visual field<br>* recording visual attention based on central or peripheral visual information<br>Procedure: eye movements recording<br>* recording of explicit visual attention based on central or peripheral visual information<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Measurement of visual acuity (central versus peripheral) |  | Day 0 | 
| Microperimetry recording (central versus peripheral) |  | Day 0 | 
| recording of automated visual field (central versus peripheral) |  | Day 0 | 
| recording of eye movements (central versus peripheral) |  | Day 0 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Measurement of visual acuity (patient versus control) |  | Day 0 | 
| Microperimetry recording (patient versus control) |  | Day 0 | 
| recording of automated visual field (patient versus control) |  | Day 0 | 
| recording of eye movements (patient versus control) |  | Day 0 |