Impact of Duration Of Absolute Voice Rest on Voice Outcome After Phonomicrosurgery

Study Overview
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Brief Summary
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Absolute voice rest is commonly prescribed after vocal fold surgery, also known as phonomicrosurgery, for benign vocal fold lesions. This is thought to decrease scarring of vocal folds, which could result in increasing tissue stiffness and limitations in optimal vocal outcome. Unfortunately there is no standardized protocol as to how long patients should rest their voice after phonomicrosurgery. To date, there are no studies in the literature directly comparing the impact of short-term and long-term voice rest on vocal fold healing and voice outcome after phonomicrosurgery.

Detailed Description
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The purpose of this study is to determine whether 3 days versus 7 days of absolute voice rest will result in different voice outcomes in patients who have undergone phonomicrosurgery for benign vocal fold lesions.

Official Title
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Impact of Duration Of Absolute Voice Rest on Voice Outcome After Phonomicrosurgery

Conditions
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Benign Neoplasm of True Vocal Cords

Intervention / Treatment
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* Behavioral: absolute voice rest


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients with benign mid membranous vocal fold lesions such as the following: Polyps Cysts Sub-epithelial fibrous mass Undergoing elective phonomicrosurgery for vocal fold lesions, which involves microflap excision +/- truncation +/- steroid injection into the vocal folds. Age 18 and older Exclusion Criteria: Patients with any of the following will be excluded from the study: Reinke's edema Active smokers Ligamentous mid membranous vocal fold lesions RRP (Recurrent Respiratory Papillomatosis) Dysplasia CIS (Carcinoma-in-situ) SCC (squamous cell carcinoma) Extent of surgery exceeds what is mentioned in the inclusion criteria (e.g., CO2 laser, balloon dilatation, vocal fold augmentation in addition to phonomicrosurgery) Previous vocal fold surgery Systemic steroids History of systemic illness that could affect wound healing

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 3 day absolute voice rest<br>participants would begin initiation of voice/speaking 3 days post phonomicrosurgery for benign vocal fold lesions | Behavioral: absolute voice rest<br>* absolute voice rest is the complete elimination of any vocalization (no sounds, speaking or whispering)<br>|
| Experimental: 7 day absolute voice rest<br>participants would begin initiation of voice/speaking 7 days post phonomicrosurgery for benign vocal fold lesions | Behavioral: absolute voice rest<br>* absolute voice rest is the complete elimination of any vocalization (no sounds, speaking or whispering)<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Voice Handicap Index - 10 |  | 3 months post op | 
| Voice Handicap Index - 10 |  | 1 month post op | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cepstral Peak Prominence (CPP) |  | 1 month and 3 months post op | 
| Average phonatory airflow in all voiced sentence |  | 1 month and 3 months post op | 
| video stroboscopy findings |  | 1 month and 3 months post op | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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phonomicrosurgery, benign vocal fold lesions, voice rest, vhi-10, CPP