Magnetic Resonance (MR) Imaging in the Post Operative Follow-up of Cholesteatoma in Children

Study Overview
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Brief Summary
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Classical imaging techniques are inaccurate to detect residual cholesteatoma. The aim of our study is to evaluate the value of diffusion-weighted MR imaging and delayed contrast enhanced T1 weighted spin-echo sequences in the detection of residual cholesteatoma in children, in a large serie of surgically verified cases.

Detailed Description
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Classical imaging techniques are inaccurate to detect residual cholesteatoma. Thin-section CT detects that the postoperative cavity is filled with a soft tissue mass. Classical MR imaging (T2 and T1 weighted spin-echo sequences) can not provide additionnal information about the nature of this filling : cholesteatoma, granulation or fibrous tissue.

Conditions
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Cholesteatoma

Intervention / Treatment
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* Other: MR Imaging


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Female or male child enters 5 and 18 years Child having benefited from a surgical operation for cholesteatoma of the average ear acquired or congenital, one-sided or bilateral Child for whom an additional operating time is indicated Child without contraindication in the MRI Child having signed a enlightened assent Child among whom the parents or the legal representatives signed a enlightened assent Exclusion Criteria: Child of less than 5 years old and more than 18 years Child presenting a chronic renal insufficiency Child for whom an additional operating time is not indicated Child having a contraindication in the MRI Child not having signed the assent or the parents of which did not sign the assent

Ages Eligible for Study
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Minimum Age: 5 Years
Maximum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: 1<br>Analysis of the value of the imaging of distribution and the late sequence to differentiate the cholesteatoma of the fibrosis in the follow-up operating post at the child | Other: MR Imaging<br>* MR imaging in the post operative follow-up of cholesteatoma in children<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Technical characteristics of the examination MRIs represented by the sensibility and the specificity of the test, with regard to the results stemming from the surgical operation |  | 24 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Only a surgical operation will confirm the diagnosis of cholesteatoma doing it again or residual. |  | 24 months | 
| It is necessary to test the following diagnostic method: the analysis of the morphological sequences in T1 and in T2 will allow to appreciate the existence or not of a filling of the cavity tympanique or the mastoïde and to clarify its localization. |  | 24 months |