Role of Herbal Dentifrices in the Management of Plaque Induced Gingivitis

Study Overview
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Brief Summary
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The clinical cross over study involves the use of two herbal based dentifirices moringa and miswak and its efficacy in reducing plaque induced gingivitis. The patients selected are provided with details regarding the research format and consent taken.

Detailed Description
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The clinical cross over study involves use of miswak and moringa dentifrices. The patients selected are 30 in no and are selected based on having gingival inflammation due to plaque accumulation. All other cases related to gingival inflammation along with patients with underlying systemic disease are excluded from the study. At baseline, plaque and gingival scores are recorded, followed by giving one of the dentifrice to the patient for brushing. The patients are asked to brush twice a day and asked to report after 72 hrs, following which another recording of plaque and gingival scores are recorded. The patients are then asked to use their own tooth paste for a period of 2 weeks as a wash out period and recalled after this 2 week interval. The patients are then given the second dentifrice and asked to brush for 72 hrs and then asked to report again for a plaque and gingival score evaluation.

Official Title
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Role of Moringa Dentifirice in the Management of Plaque Induced Gingivitis. A Clinical Crossover Study

Conditions
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Gingiva; Infection, Plaque, Dental

Intervention / Treatment
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* Other: dentifrice


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: subjects having only plaque induced gingival inflammation Exclusion Criteria: Subjects having gingival inflammation related to underling systemic diseases Subjects taking medications Gingival inflammation related to other causes

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Crossover Assignment
Interventional Model Description: sample size of 30- First group of 15 subjects recording of plaque and gingival scores were recorded. Patients were given first dentifrice and asked to brush for 72 hours and then asked to report. A washout period of 2 weeks followed. The next round, the subjects were given the second dentifrice and asked to brush for 72 hrs and then after a period of 3days asked to report
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: moringa<br>First phase of subjects were given dentifrice for brushing | Other: dentifrice<br>* use of dentifrices for brushing<br>|
| Active Comparator: miswak<br>second phase of subjects were given dentifrice for brushing | Other: dentifrice<br>* use of dentifrices for brushing<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| plaque scores | plaque score recorded using calibrated periodontal probes | 72 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Gingival inflammation scores | Gingival bleeding scores recorded using caliberated periodontal probes | 72 hours | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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miswak, moringa, plaque, gingival bleeding