linjc16/ctgov huggingface dataset:
Effectiveness of Periodontal Treatment for the Glycemic Conttrol of Type II Diabetes Mellitus

Study Overview
=================
Brief Summary
-----------------
The project is intended to find out the effect of Periodontal treatment for the glycemic control of type II diabetes mellitus patients.

Official Title
-----------------
Effectiveness of Periodontal Treatment for the Glycemic Conttrol of Type II Diabetes Mellitus

Conditions
-----------------
Patient Compliance

Intervention / Treatment
-----------------
* Procedure: periodontal care


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients having Diabetes Mellitus and diagnosed with Periodontitis for last six months. Aged between 30-60 years. Patients with HbA1C level 7-9.5%, measured within three months prior to present study. Exclusion Criteria: Patients with acute oral infection Need for immediate tooth extractions Severe Hypertension (>180/110 mm Hg) Edentulous Patients Patients with Diabetic Nephropathy Patients with Diabetic Retinopathy

Ages Eligible for Study
-----------------
Minimum Age: 30 Years
Maximum Age: 60 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Health Services Research
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: treatment group<br> | Procedure: periodontal care<br>* periodontal treatment<br>|
| No Intervention: control group<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change of HbA1C between the control group and interventional group. | The primary outcome of the trial | one year |
Are Medical Personnel Can Correctly Recognize the Chest Sounds?

Study Overview
=================
Brief Summary
-----------------
The study aims to validate the interpretation of breath sounds by medical personnel

Detailed Description
-----------------
task of the participants in the study to determine the chest sound based on specific sounds

Official Title
-----------------
Are Medical Personnel Can Correctly Recognize the Chest Sounds?

Conditions
-----------------
Respiration, Artificial

Intervention / Treatment
-----------------
* Other: Sound


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: give voluntary consent to participate in the study paramedics, nurses, physicians Exclusion Criteria: not meet the above criteria

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: questionnaire<br>task of the participants in the study to determine the chest sound based on specific sounds | Other: Sound<br>* task of the participants in the study to determine the chest sound based on specific sounds: Vesicular - Diminished; Expiratory Wheeze; Bronchovesicular; pneumonia; pulmonary Oedema; Stridor; Agonal respiration<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| breathing sounds measured by questionnaire | study participants selective listening to breath sounds, must mark in questionnaire what is the type of sound. 8 questions. | 1 day |
Interest of Continuous Ropivacaine Administration Through an Elastomeric Pump (Pain Buster) for the Surgery of Latissimus Dorsi and Serratus Micro Anastomotic Flaps

Study Overview
=================
Brief Summary
-----------------
Continuous bupivacaine administration through an elastomeric pump (Pain Buster) has been found effective for post operative analgesia in a large range of surgery. Ropivacaine is a less toxic drug, never tested in the surgery of latissimus dorsi and serratus micro anastomotic flaps (from the investigators knowledge). The aim of the study is to evaluate the usefulness of this drug and device for post operative analgesia, associated with patient controlled analgesia with morphine. For this purpose a controlled randomized double blind trial against placebo (saline) is performed, enrolling 40 (20x2) patients during 3 years, in order to measure total morphine consumption during the first 48 post operative hours and to evaluate analgesia and sides effects of morphine in each group.

Official Title
-----------------
Interest of Continuous Ropivacaine Administration Through an Elastomeric Pump (Pain Buster ) for the Surgery of Latissimus Dorsi and Serratus Micro Anastomotic Flaps

Conditions
-----------------
Post Operative Analgesia

Intervention / Treatment
-----------------
* Drug: Naropeine (Ropivacaine)
* Drug: Placebo


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: operated for latissimus dorsi and serratus micro anastomotic flaps. 18 to 75 years old ASA I-II hospitalized in Nantes CHU Burns ICU giving their written informed consent with healthcare protection Exclusion Criteria: declining the study with known sides effects with morphine and local anesthetics with known allergy or other reaction with used drugs with disease incompatible with anaesthetic procedure under law protection taking antiepileptic or antidepressant drugs pregnant (not any gender criteria)

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Placebo Comparator: Placebo<br> | Drug: Placebo<br>* saline<br>|
| Experimental: Active<br> | Drug: Naropeine (Ropivacaine)<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Total morphine consumption |  | H 48 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Ropivacaine, elastomeric pump, patient controlled analgesia, morphine consumption
Persistent Low Back and Pelvic Pain 3-6 Months Post Partum

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to identify how many females have persistent low back pain and/or pelvic pain 3-6 months post partum. The females that have persistent pelvic pain can continue in the study and be examined by a chiropractor. They will then divide the females into Hanne Alberts 5 subgroups of pelvic pain. The females that have one-sided pelvic pain will be invited to participate in a randomised controlled study where chiropractic intervention is compared to exercises.

Detailed Description
-----------------
The study is a follow up study to Prevalence of low back pain and pelvic pain in the pregnant population in Stavanger.

Official Title
-----------------
Persistent Low Back Pain and Pelvic Pain 3-6 Months Post Partum

Conditions
-----------------
Pelvic Girdle Pain Post Partum, Low Back Pain Post Partum

Intervention / Treatment
-----------------
* Other: exercise advise
* Other: chiropractic treatment and exercises


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Low back and\or pelvic girdle pain during pregnancy Fluent understanding of spoken and written Norwegian Exclusion Criteria: hospitalisation due to pain or complications post partum

Ages Eligible for Study
-----------------
Minimum Age: 16 Years
Maximum Age: 50 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Chiropractic treatment, exercise<br>Chiropractic treatment and exercise | Other: chiropractic treatment and exercises<br>* Manipulation, mobilisation, soft tissue work, ergonomic and exercise advise. Maximum 12 treatments<br>* Other names: chiropractic;|
| Experimental: Exercises<br>Exercise advise | Other: exercise advise<br>* Exercises<br>* Other names: chiropractic;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Oswestry Disability Index |  | 20 weeks after the initial assessment | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
low back pain, pelvic pain, pelvic girdle pain, post partum
IMS-treatment and Canalis Carpi Syndrome

Study Overview
=================
Brief Summary
-----------------
Carpal tunnel syndrome is a condition in which the median nerve is compressed at the wrist, leading to paresthesias, numbness and muscle weakness in the hand. Treatment of the condition often involves surgery. In this study we wish to se if there is an effect of using intramuscular stimulation (IMS) to release the tension of nervus medianus in the lower arm. The study will be performed by randomization to IMS of musculus pronator teres or a control (Scam IMS treatment to the acupuncture point Li11). The two insertion points are approximately 1cm apart in the lower arm.

Detailed Description
-----------------
The most important outcome measure is ultra sound measured diameters for nervus medianus in the carpal tunnel

Official Title
-----------------
An Randomized Controlled Trial of IMS-treatment Versus Scam for Canalis Carpi Syndrome

Conditions
-----------------
Carpal Tunnel Syndrome

Intervention / Treatment
-----------------
* Device: Needle in acupuncture point Li11
* Device: IMS of the musculus pronator teres


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Canalis Carpi Syndrome verified by ultrasound and clinically Both genders Age from 18 to 67 Exclusion Criteria: Negative neurophysiology result. Epilepsy, Heart disease, Rheumatism Unstable angina pectoris, Metal -allergy, Needle- phobia, Infection Hemophilia Cognitive problems

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 67 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Sham Comparator: Needle in acupuncture point Li11<br>Acupuncture needle in the acupuncture point Li11 | Device: Needle in acupuncture point Li11<br>* Acupuncture needle in acupuncture point Li11<br>* Other names: Needles;|
| Experimental: IMS of musculus pronator teres<br>Acupuncture needle in musculus pronator teres | Device: IMS of the musculus pronator teres<br>* Acupuncture needle in musculus pronator teres<br>* Other names: Needles;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Diameter of the Nervae medianus in the Carpal Tunnel |  | End 2011 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Health complaints |  | End 2011 | 
| Power of the hand grip |  | End 2011 |
Inspiratory Muscle Training in Ehlers Danlos Patients

Study Overview
=================
Brief Summary
-----------------
Evaluation of the effect of inspiratory muscle training in Ehlers Danlos patients

Conditions
-----------------
Ehlers Danlos

Intervention / Treatment
-----------------
* Device: Threshold inspiratory muscle training


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: a diagnosis for Ehlers Danlos syndrome combining genetics and clinical examination no infectious exacerbation in the last four weeks Exclusion Criteria: respiratory comorbidities

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Inspiratory muscle training group<br>Threshold inspiratory muscle training | Device: Threshold inspiratory muscle training<br>* Inspiratory muscle training<br>|
| No Intervention: Control group<br>No training | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| inspiratory muscle strength measured by sniff nasal inspiratory pressure |  | 2 minutes | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| walked distance measured by six minutes walking test |  | 6 minutes | 
| lung function by spirometry |  | 5 minutes | 
| anxiety by hospital anxiety depression scale |  | 2 minutes |
Comparison of Prophylactic Clip and Detachable Snare

Study Overview
=================
Brief Summary
-----------------
Although endoscopic colonic polypectomy has been an established procedure for two decades, the risk of bleeding is still higher after resecting of pedunculated polyps, because of the presence of a large artery in the stalk. Several preventive methods such as detachable snare and adrenaline injection have been proposed in the management of postpolypectomy bleeding in large colonic polyps. For prophylactic clip, there was no prospective randomized study assessing the efficacy in the prevention of postpolypectomy bleeding for the large pedunculated polyps. So we designed a prospective, randomized study to compares the efficacy of application of prophylactic clip and detachable snare in the prevention of postpolypectomy bleeding in large polyps. Application of prophylactic clip will be as effective and safe method as detachable snare in the prevention of postpolypectomy bleeding for the large pedunculated colonic polyps.

Official Title
-----------------
Comparison of Clip and Detachable Snare in Preventing Postpolypectomy Bleeding for Pedunculated Colonic Polyps: a Prospective, Randomized Study

Conditions
-----------------
Colonic Polyp

Intervention / Treatment
-----------------
* Procedure: Prophylactic clip
* Procedure: Detachable snare


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with pedunculated colorectal polyps, the heads of which were larger than 10mm and the stalk of which were large than 5 mm in diameter, were included. Exclusion Criteria: bleeding tendency poor preparation sessile polyp
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Prophylactic clip<br>Prophylactic clip | Procedure: Prophylactic clip<br>* Before conventional snare polypectomy, hemoclips were applied on the base of stalk in the prophylactic clip group<br>|
| Active Comparator: Detachable snare<br>Detachable snare | Procedure: Detachable snare<br>* In the detachable snare group, detachable snare was positioned at the base of stalk and followed by conventional snare polypectomy<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postpolypectomy bleeding |  | Immediate (bleeding occurring immediately after polypectomy and lasting for 30 s or more) and delayed bleeding complications were assessed. Delayed bleeding was subdivide into early (<24 h) and late (>24 h-30 days). |
Biological Collection of Brain Tumors

Study Overview
=================
Brief Summary
-----------------
The objective of this study is to build a collection of biological samples from patients with brain tumors.

Official Title
-----------------
Biological Collection of Brain Tumors - GLIOLI Collection

Conditions
-----------------
Brain Tumor

Intervention / Treatment
-----------------
* Biological: blood and/or csf collection


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patient whose diagnosis of brain tumor has been confirmed. Adult patients, from 18 years old and without upper age limit Patient affiliated to a social security scheme or equivalent. Patient able to consent, having dated and signed an informed consent Exclusion Criteria: Pregnant or breastfeeding women Patient under guardianship or curators. Persons deprived of their liberty by a judicial or administrative decision

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| brain tumors<br> | Biological: blood and/or csf collection<br>* blood and/or collection Only once : 1 tube of blood of 4 mL on dry tube with or without gel, 2 tubes of blood of 4 mL on EDTA tube, If CSF collected for diagnosis is available, it can be sent for storage in the collection.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| number of biological samples | number of biological samples | 10 years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Brain tumor
Surgery or Capsular Distention With Steroid in the Treatment of Primary Frozen Shoulder?

Study Overview
=================
Brief Summary
-----------------
The purpose of the study is to compare two different treatment regimens for primary frozen shoulder: Arthroscopic capsulotomy and arthrographic distention with steroid.

Detailed Description
-----------------
Patients with primary frozen shoulder will be randomized to two different treatments and the outcome will be measured.

Official Title
-----------------
Arthroscopic Capsulotomy vs Arthrographic Distention With Steroid in the Treatment of Primary Frozen Shoulder. A Randomized Study

Conditions
-----------------
Adhesive Capsulitis

Intervention / Treatment
-----------------
* Procedure: Arthroscopic capsular release
* Procedure: Distention with steroid


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: The patient must have understood all information about the project and must have signed the informed consent letter about participation in the study including rehabilitation and follow-up The patients must have a history and clinical findings typical for primary frozen shoulder with globally reduced range of motion in the shoulder. External rotation 20 degrees or less Abduction 45 degrees or less The patients must not be in phase 1 (inflammation phase) Diabetics may be included MRI must be taken to exclude other reasons for stiffness Exclusion Criteria: Other reasons for stiffness( cuff rupture, arthritis) Posttraumatic or postoperative stiffness Patients not suited for day surgery Patients with a history of subacromial impingement before developing stiffness

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Arthroscopic Capsulotomy<br>Arthroscopic capsular release | Procedure: Arthroscopic capsular release<br>* Surgical division of thickened capsule in the shoulder<br>|
| Active Comparator: Distention with steroid<br>Arthrographic distention with contrast, saline, steroid and local anaesthetic | Procedure: Distention with steroid<br>* Intraarticular distention with steroid, saline, contrast and local anaesthetic<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Shoulder Function |  | 2 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Shoulder range of motion |  | 2 years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Randomized study capsulotomy vs distention with steroid