CardiOvascular Risk and idEntificAtion of Potential High-risk Population in Acute Myocardial Infarction

Study Overview
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Brief Summary
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The purpose of this registry is to evaluate long-term clinical events in patients with acute myocardial infarction who were treated with percutaneous coronary intervention. Although numerous articles have been published by using nationwide Korean myocardial infarction registries, such as the Korea Acute Myocardial Infarction Registry (KAMIR), limitation of previous registries is that these have little data beyond the first year of MI. Therefore, current registry was designed to assess long-term clinical events in patients with acute myocardial infarction. Because most of myocardial infarction patients were treated by revascularization in real world of Korea, this registry limits the inclusion criteria to patients who were treated with percutaneous coronary intervention to reduce the bias.

Detailed Description
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Cardiovascular center with high-volume percutaneous coronary intervention of following hospitals were participated. Seoul St. Mary's Hospital, Seoul, South Korea Yeoido St. Mary's Hospital, Seoul, South Korea Uijongbu St. Mary's Hospital, Gyeonggi-do, South Korea St. Paul Hospital, Seoul, South Korea Bucheon St. Mary's Hospital, Gyeonggi-do, South Korea Incheon St. Mary's Hospital, Incheon, South Korea St. Vincent Hospital, Gyeonggi-do, South Korea Deajon St. Mary's Hospital, Daejeon, South Korea Cheonnam University Hospital, Gwangju, South Korea 8 hospitals of the Catholic University of Korea already have web-based coronary intervention registry (NCT01239914). And Cheonnam University Hospital is one of leading hospitals to design and manage the web-based previous Korean nationwide myocardial infarction registry, such as such as the Korea Acute Myocardial Infarction Registry (KAMIR) (http://www.kamir.or.kr/). All consecutive acute myocardial infarction patients had been enrolled in each registries prospectively. Using these previous data, current registry update new clinical and angiographic variables and assess long-term clinical follow-up data retrospectively.

Official Title
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CardiOvascular Risk and idEntificAtion of Potential High-risk Population in Korean Patients With Acute Myocardial Infarction Registry (COREA-AMI)

Conditions
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Long-term Major Cardiovascular Events, Myocardial Infarction, Percutaneous Coronary Intervention

Intervention / Treatment
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* Device: Percutaneous coronary intervention
* Device: Percutaneous coronary intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Acute myocardial infarction who were treated with percutaneous coronary intervention Exclusion Criteria: Acute myocardial infarction who were managed by conservative strategy Acute myocardial infarction who were not treated with percutaneous coronary intervention

Ages Eligible for Study
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Minimum Age: 20 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| ST-segment elevation AMI<br>ST-segment elevation acute myocardial infarction teated with percutaneous coronary intervention | Device: Percutaneous coronary intervention<br>* Percutaneous coronary intervention<br>|
| Non-ST-segment elevation AMI<br>Non-ST-segment elevation acute myocardial infarction teated with percutaneous coronary intervention | Device: Percutaneous coronary intervention<br>* Percutaneous coronary intervention<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Major adverse cardiac and cerebrovascular events |  | 5 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| All-cause death |  | 5 years | 
| Cardiac death |  | 5 years | 
| Nonfatal myocardial infarction |  | 5 years | 
| Nonfatal stroke |  | 5 years | 
| Target lesion revascularization |  | 5 years | 
| Target vessel revascularization |  | 5 years | 
| Non-target vessel revascularization |  | 5 years | 
| Definite/Probable stent thrombosis |  | 5 years | 
| Hospitalization for heart failure |  | 5 years | 
| Bleeding defined as the Bleeding Academic Research Consortium (BARC) definitions type 2, 3, and 5 |  | 5 years | 
| Bleeding defined as the thrombolysis In Myocardial Infarction (TIMI) major/minor |  | 5 years |