Evaluating Anti-Tobacco Message Effectiveness Among Lesbian, Gay, Bisexual, and Transgender Young Adults

Study Overview
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Brief Summary
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This trial refines and evaluates anti-tobacco messages among lesbian, gay, bisexual, and transgender (LGBT) young adults at risk for the use of more than one tobacco product (polytobacco use). Polytobacco use is associated with nicotine dependence and tobacco use into adulthood, and is disproportionately high among LGBT young adults. This trial seeks to determine effective communication of polytobacco use risk to at-risk LGBT young adults.

Detailed Description
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PRIMARY OBJECTIVES: I. Identify absolute and relative risk anti-tobacco messages that effectively communicate polytobacco risks to lesbian, gay, bisexual, transgender (LGBT) young adults. Participants view anti-tobacco messages and rate them for perceived effectiveness and reactance.

Official Title
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The Effect of Nicotine and Tobacco Message Framing on Use Among Diverse Groups of Young Adults

Conditions
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Tobacco-Related Carcinoma

Intervention / Treatment
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* Other: Health communications


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Young adults (age 18-35 years) Live in the United States At least 50% of the sample also: Are susceptible to multiple nicotine and tobacco product use (i.e., have used combustible tobacco or e-cigarettes at least once)

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 35 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: AR-Quit<br>Participants view messages with absolute risk and quit statements | Other: Health communications<br>* Participants are assigned to view health communications with risk and efficacy statements.<br>|
| Experimental: AR-Switch<br>Participants view messages with absolute risk and switch statements | Other: Health communications<br>* Participants are assigned to view health communications with risk and efficacy statements.<br>|
| Experimental: AR-Combination<br>Participants view messages with absolute risk and combination quit+switch statements | Other: Health communications<br>* Participants are assigned to view health communications with risk and efficacy statements.<br>|
| Experimental: RR-Quit<br>Participants view messages with comparative risk and quit statements | Other: Health communications<br>* Participants are assigned to view health communications with risk and efficacy statements.<br>|
| Experimental: RR-Switch<br>Participants view messages with comparative risk and switch statements | Other: Health communications<br>* Participants are assigned to view health communications with risk and efficacy statements.<br>|
| Experimental: RR-Combination<br>Participants view messages with comparative risk and combination quit+switch statements | Other: Health communications<br>* Participants are assigned to view health communications with risk and efficacy statements.<br>|
| Other: Control<br>Participants view FDA regulatory messages | Other: Health communications<br>* Participants are assigned to view health communications with risk and efficacy statements.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Message Perceived Effectiveness - Persuasive Potential. | 6 items measured on 5-point scale, 1 = Not at all and 5 = Very much These messages were worth remembering. These messages grabbed my attention. These messages are powerful. These messages are convincing. These messages are meaningful. These messages are informative. Responses were summed and averaged to create a scale for intention to quit (range from 1 - 5). Higher scores indicate a higher persuasive potential of the message. | Immediately post-exposure to intervention, up to 1 hour | 
| Perceived Effectiveness - Perceived Behavioral Impact | Six items were analyzed separately, each scored on 5-point Likert scale (1=Strongly Disagree, 5=Strongly Agree) These messages will motivate CIGARETTE SMOKERS to switch to vaping. These messages will motivate people to quit ALL smoking and vaping. These messages will motivate NON-USERS to start vaping. These messages will motivate NON-USERS to start smoking cigarettes. These messages will motivate CIGARETTE SMOKERS to quit. These messages will motivate VAPERS to quit. | Immediately post-exposure to intervention, up to 1 hour | 
| Risk Perceptions: Absolute/Relative Risks of Cigarette vs. E-cigarette Use | On a scale from 0-10, where 0 = not at all harmful and 10 = extremely harmful now harmful are ... to your health? combustible cigarettes nicotine vapes On a scale from 0-10, where 0 = much less harmful and 10 = much more harmful... • compared to combustible cigarettes, how harmful are nicotine vapes to your health? | Immediately post-exposure to intervention, up to 1 hour | 
| Behavioral Intentions to Use Tobacco | 8-items made up two 4-pt scales (1 = definitely will not and 4 = definitely will). Items for each scale were summed and averaged. Higher scores indicate higher likelihood of avoiding cigarettes/nicotine vapes. How likely it is that in the next 3 months, you will refrain from... smoking cigarettes completely and permanently? smoking cigarettes when you get lonely? smoking cigarettes when you are with your friends who use them? smoking cigarettes when someone hands you a cigarette? How likely it is that in the next 3 months, you will refrain from... vaping nicotine completely and permanently? vaping nicotine when you get lonely? vaping nicotine when you are with your friends who use them? vaping nicotine when someone hands you a vape? | Immediately post-exposure to intervention, up to 1 hour |