WBV Training on Physical Function and Muscle Strength in Knee OA

Study Overview
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Brief Summary
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In this study compare different frequencies of whole body vibration training on physical function and muscle strength in patients with knee osteoarthritis.

Detailed Description
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This randomized controlled trial is to compare different frequencies of whole-body vibration (WBV) training on physical function and quadriceps muscle strength in patients with knee osteoarthritis and further will be researched which frequencies are effective for knee OA patients and how much WBV training is useful modality for knee osteoarthritic patients. This research will have significant effects in improving muscle strength and functional level of knee OA patients.

Official Title
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Comparison of Different Frequencies of Whole Body Vibration Training on Physical Function and Muscle Strength in Patients With Knee Osteoarthritis

Conditions
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Knee Osteoarthritis

Intervention / Treatment
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* Other: WBV technique
* Other: Whole body vibration technique


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 40-70 years Both genders Kellgren and Lawrance grade 2 and 3. Pain symptoms for at least 3 months Had no previous experience in WBV Exclusion Criteria: Knee surgery in the past 6 months Patient with acute symptomatic knee OA Unable to walk unaided Diagnosed with other muscular and joint disease that affect the lower limb function Patient with any neurological conditions History of trauma to knee joint during last week.

Ages Eligible for Study
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Minimum Age: 40 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Whole Body Vibration Technique<br>WBV training with the frequency of 16-25 Hz along with conventional treatment. | Other: WBV technique<br>* Whole body vibration with frequency of 16-25 Hz were given from week 1-8 for 10 minutes/10 repetitions. Time were increased weekly Convention therapy were hot pack 10 minutes, stretching exercise (SLR) 10 repetition x 3 sets and quadriceps exercise 10 repetition x 3 sets. 3 session/week for 8 weeks<br>|
| Active Comparator: WBV Technique<br>WBV training with the frequency of 26-35 Hz along with conventional treatment. | Other: Whole body vibration technique<br>* Whole body vibration with frequency of 26-35 Hz were given from week 1-8 for 10 minutes/10 repetitions. Time were increased weekly Convention therapy were hot pack 10 minutes, stretching exercise (SLR) 10 repetition x 3 sets and quadriceps exercise 10 repetition x 3 sets. 3 session/week for 8 weeks<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) | Changes from base line WOMAC is a widely used self-administered health status measure used in assessing pain, stiffness, and function in patients with OA of hip and knee. It consists of 3 sections with the total score of 96 | 8 week | 
| 1 Repetition maximum (1 RM) | Changes from base line 1 RM measure muscle strength with maximum amount of weight that a person can possibly lift for one repetition | 8 week | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual Analog Scale (VAS) | Changes from baseline visual analog scale for pain starting from 0-10 | 8 week | 
| Timed up and Go test (TUG) | Changes from baseline time up and go test to determine fall risk and measure the progress of balance, sit to stand and walking. | 8 week | 
| 6 minute walk test | Changes from baseline 6 minute walk test measures the distance an individual is able to walk over a total of six minutes on a hard, flat surface | 8 week | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Knee Osteoarthritis, Physical Function, Muscle Strength, Whole Body Vibration