The Effect of Pranayamic Techniques on Obstructive Sleep Apnea Syndrome

Study Overview
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Brief Summary
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Study was planned to investigate the effect of pranayama on dyspnea, daytime sleepiness, cognitive function, quality of life, activities of daily living, functional exercise capacity, physical activity level, sleep quality, fatigue, musculoskeletal pain, depression and anxiety in OSAS.

Detailed Description
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Thirty-four OSAS patients meeting the inclusion criteria will be randomized into 2 groups as pranayama and control groups. The pranayama group will practice pranayama on their own for 8 weeks, 7 days a week, 3 times a day for 15 minutes. In addition, he will perform a single 15-minute session 3 days a week online under the supervision of a physiotherapist. The control group will not receive any intervention. Dyspnea sensation before and after the training Modified Medical Research Council dyspnea scale, daytime sleepiness Epworth Sleepiness Scale, cognitive function Montreal Cognitive Assessment Scale, quality of life Short Form-36, Turkish Adaptation of Nottingham Health Profile Questionnaire and Functional Outcomes of Sleep Questionnaire, activities of daily living London Chest Activities of Daily Living Scale, functional exercise capacity 30 seconds sit and stand test, physical activity level International Physical Activity Questionnaire-Short Form, sleep quality Pittsburgh Sleep Quality Index, fatigue status Fatigue Severity Scale, depression and anxiety Hospital Anxiety and Depression Scale, musculoskeletal system pain will be assessed with the Nordic Musculoskeletal Questionnaire.

Official Title
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The Effect of Pranayamic Techniques on Obstructive Sleep Apnea Syndrome

Conditions
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Obstructive Sleep Apnea Syndrome

Intervention / Treatment
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* Other: Ujjayi pranayama, Nadi-Shodhana pranayama, Sukha pranayama


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients diagnosed with mild to moderate obstructive sleep apnea syndrome. Exclusion Criteria: Using a mandibular advancement device Regularly using hypnotic drugs Have a metabolic disease (eg diabetes, hypothyroidism, obesity) Have Hypertension Have Malignancy Have Epilepsy Have Heart failure Have COPD Have asthma Neurological, psychological, cooperative problems Having a history of maxillofacial surgery

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Participants will be randomly divided into two groups as pranayama group and control group.
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Pranayama Group<br>Participants in this group will apply a 45-minute training program at home, consisting of 5 minutes of Ujjayi pranayama, 5 minutes of Nadi-Shodhana pranayama and 5 minutes of Sukha pranayama, 7 days a week for 8 weeks, 3 times a day. In addition, they will perform a 15-minute session 3 day a week for 8 weeks, under the online supervision of a physiotherapist. The training program will last 8 weeks. | Other: Ujjayi pranayama, Nadi-Shodhana pranayama, Sukha pranayama<br>* Ujjayi pranayama:It is a pranayamic application that is performed by slightly twisting the throat and breathing through the nose. Nadi shodhana pranayama is breathing alternately through the right and left nostrils.Sukha pranayama is inhaled through the nose for 5 seconds, then given through the nose for 5 seconds. Thus, 6 times of inspiration and expiration is done per minute.<br>|
| No Intervention: Control Group<br>No intervention will be made to this group. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Vital Capacity | Vital capacity will be measured in liters, which is one of the respiratory functions. | 8 weeks | 
| Functional Exercise Capacity | It will be evaluated by the 6-minute walking test. | 8 weeks | 
| Dyspnoea | The resting dyspnea level will be evaluated according to the Modified Borg Scale. | 8 weeks | 
| fatigue | Fatigue level will be assessed using the Fatigue Severity Scale (FSS). | 8 weeks | 
| Anxiety and Depression Status | It will be evaluated with the Hospital Anxiety Depression Scale. | 8 weeks | 
| Physical Activity Level | It will be evaluated with the International Physical Activity Questionnaire-Short form (IPAQ-S). | 8 weeks | 
| Cognitive Function | Cognitive evaluation of the patients will be made with the Montreal Cognitive Assessment Scale (MOCA). | 8 weeks | 
| Daily Life Activities | Daily life activities will be evaluated with the London Chest Daily Living Activities Scale. | 8 weeks | 
| Daytime Sleepiness | Daytime sleepiness will be assessed with the Epworth Sleepiness Scale (ESS). | 8 weeks | 
| Sleep Quality | Sleep quality will be evaluated with the Pittsburg Sleep Quality Index (PSQI). | 8 weeks | 
| Life Quality | Quality of life will be evaluated with the SF-36 scale. | 8 weeks | 
| Inspiratory Muscle Strength | Inspiratory muscle strength will be evaluated by measuring the maximum inspiratory pressure (MIP) in cmH2O. | 8 weeks | 
| Forced Vital Capacity | Forced Vital Capacity will be measured in liters, which is one of the respiratory functions. | 8 weeks | 
| Expiratory Muscle Strength | Expiratory muscle strength will be evaluated by measuring the maximum expiratory pressure (MIP) in cmH2O. | 8 weeks |