The Impact of Perioperational Malnutrition on the Cost on Gastroenterological Cancer Patients

Study Overview
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Brief Summary
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Undernutrition is a state marked by energy and/or protein intake deficiency or mal-absorption, and is often described as protein energy malnutrition (PEM). Malnutrition is common in hospitalized patients worldwide. The prevalence of malnutrition in hospitalized patients range from 20% - 50%, depends on the varieties of diseases, health system, population and assessment tools. It is well documented in Western countries that malnutrition affects clinical outcomes negatively. Compared with well-nourished patients, patients with malnutrition stay longer in hospitals and related cost is significantly higher. There is increasing evidence which indicates that appropriate nutrition support (e.g., standardized nutrition screening procedures, delivering nutrients with appropriate path, etc) may improve clinical outcome on malnutrition, along with cost saving. To date, there is no study to document specifically the impact of malnutrition and related nutrition support on the health economics in China. Considering China now is on its way to establish public health security system and a diagnosis-related grouping system, the understanding of the cost effectiveness of nutrition support under the current clinical conditions is crucial. This study aims to investigate the prevalence of perioperational malnutrition in gastroenterological cancer patient, the nutrition support status and related health economic effects.

Official Title
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Malnutrition and Its Impact on the Perioperational Hospitalization Cost: A Prospective, Cohort Study on Gastroenterological Cancer Patients

Conditions
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Malnutrition, Gastroenterological Cancer, Surgical Procedures, Operative

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 18 or older With gastroenterological cancer Will receive resectional operation Consent informed Exclusion Criteria: With severly cardiac, pulmonary, liver or renal disease With endocrine or metabolic disease With dyslipidemia Without consent

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Malnutrition cohort<br>The patients with undernutrition | |
| Well nourished cohort<br>Patient that well nourished and without undernutrition | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cost |  | 30 days after operation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mortality |  | 30 days after operation | 
| Infectious morbidity |  | 30 days after operation | 
| Length of hospitalization |  | 30 days after operation | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Nutritional Support