Internet-administrated Treatment of Anxiety Disorders

Study Overview
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Brief Summary
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The purpose of this study is to determine whether tailored internet-administered cbt is a feasible treatment for anxiety disorders in clinical settings.

Official Title
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Tailored Internet-administrated Treatment of Anxiety Disorders - A Randomised Controlled Trial (NOVA II)

Conditions
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Anxiety Disorders, Depression

Intervention / Treatment
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* Behavioral: Tailored Internet-administrated CBT-Treatment
* Behavioral: Waitlist


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: over 18 years fulfill the criteria for at least one anxiety syndrome Exclusion Criteria: ongoing psychological treatment suicidal prone ongoing alcohol addiction

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: tailored internet-administrated CBT<br>Behavioral: tailored internet-administrated CBT | Behavioral: Tailored Internet-administrated CBT-Treatment<br>* This intervention contains up to 6-10 text-based self-help modules in which 4 modules are fixed (the first three and the last) and the rest are prescribed following the diagnostic telephone interview. These modules contain material on panic disorder, social phobia, stress management, assertiveness training, concentration, relaxation among other things.<br>|
| Active Comparator: waitlist<br>waitlist | Behavioral: Waitlist<br>* active waitlist<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change from baseline in Clinical Outcome in Routine Evaluation - Outcome Measure (CORE-OM) | Measures anxiety and depressive symptoms. Change from baseline in anxiety and depressive symptoms expected between time frames. | Two weeks pre treatment (baseline), two weeks post treatment, and 12 months post treatment | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change from baseline in Beck Anxiety Inventory (BAI) | Measures anxiety symtoms. Change from baseline in anxiety symptoms expected between time frames. | Two weeks pre treatment (baseline), two weeks post treatment, 12 months post treatment | 
| Change from baseline in Montgomery Åsberg Depression Rating Scale-Self Rated (MADRS-S) | Measures depressive symptoms. Change from baseline in depressive symptoms expected between time frames. | Two weeks pre treatment (baseline), two weeks post treatment, and 12 months post treatment | 
| Change from baseline in Quality of Life Inventory (QOLI) | Measures quality of life. Change from baseline in quality of life expected between time frames. | Two weeks pre treatment (baseline), two weeks post treatment, and 12 months post treatment |