Management of Paroxystic Atrial Fibrillation in French Intensive Care Units

Study Overview
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Brief Summary
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The primary purpose of the study is to evaluate treatment of new onset atrial fibrillation in french ICU.

Detailed Description
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Atrial fibrillation (AF) is a common arrhythmia in the ICU and is associated with significant morbidity. However, curative treatment remains unclearly established. In fact, there are no specific recommendations for new onset atrial fibrillation in ICU and only few studies have assessed this topic. The PAF-ICU trial is an observational, prospective, multicenter, transversal trial. The main objective is to evaluate the management of paroxytic atrial fibrillation that occur in ICU. The investigators want to document 2500 episodes of paroxystic atrial fibrillation in 50 ICU centers. In each center, the episodes are included consecutively until the required 50 episodes are obtained for each center. A patient can present several episodes and each episode can be included in the study. A new episode is considered as such if it occurs more than one hour after the previous episode. The follow-up period for each patient corresponds to the ICU stay.

Official Title
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Management of Paroxystic Atrial Fibrillation in French Intensive Care Units

Conditions
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New Onset Atrial Fibrillation, ICU Patients

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age > 18 years Patient hospitalized in ICU New onset atrial fibrillation Exclusion Criteria: Age < 18 years Parturient or breast-feeding woman Persistent or permanent atrial fibrillation Patients after cardiovascular or thoracic surgery Patients with therapeutic limitations

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Management of Atrial Fibrillation | All types of therapeutics used to manage atrial fibrillation are collected | ICU stay (until 28 days) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cardiac rhythm status | Type of rhythm : Normal (sinus rhythm), Atrial Fibrillation, Other disturbance | Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation | 
| Blood pressure | Blood pressure. Unit : Millimeters of mercury | Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation | 
| Heart rate | Heart rate. Unit : beats per minute | Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation | 
| Cardiac output | Product of the heart rate (HR) and the stroke volume (SV), which is the volume of blood pumped from the ventricle per beat. Unit : L/min. | Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation | 
| ScvO2 | Venous saturation. Unit : percentage | Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation | 
| Vasopressors | Type of vasopressors used | Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation | 
| Stroke | Occurrence of stroke during ICU stay | ICU Stay up to 28 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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New onset atrial fibrillation, Paroxystic atrial fibrillation, ICU patients, Rate control, Rhythm control