Impact of Nutritional Deficit in Emergency Surgery

Study Overview
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Brief Summary
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Patients in emergency settings might become malnourished. There are different ways to identify the group as 'at risk' of malnutrition. There are also several different ways to measure outcomes. This pilot study will look at patients undergoing emergency laparotomy, investigate relationships between different selection criteria and outcome measures, and test feasibility of outcome measure collection.

Detailed Description
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Patients in emergency settings might become malnourished. There are different ways to identify the group as 'at risk' of malnutrition. There are also several different ways to measure outcomes. This pilot study will look at patients undergoing emergency laparotomy, investigate relationships between different selection criteria and outcome measures, and test feasibility of outcome measure collection.

Official Title
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Impact of Nutritional Deficit in Emergency Surgery: A Pilot Study

Conditions
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Emergencies, Surgery, Malnutrition

Intervention / Treatment
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* Procedure: Emergency laparotomy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Willing to consent, -≥ 18 years old eligible for inclusion in National Emergency Laparotomy Audit first procedure during admission (<7 days from admission). Exclusion Criteria: Recent discharge from hospital (within 60 days), unable to provide informed consent life expectancy <12 months prisoners lack mental capacity language barrier affecting ability to provide consent

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients with acute intra-abdominal pathology<br>Patients admitted to hospital with acute intra-abdominal pathology | Procedure: Emergency laparotomy<br>* Midline laparotomy for acute intra-abdominal pathology<br>* Other names: Celiotomy;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Time without nutrition (measured in days) | This is defined as the time elapsed between last normal enteral intake, and resumption of enteral intake, or naso-enteric feeding, or parenteral nutrition. | within 90 days of admission to hospital | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| In hospital complications | Complications related to surgery measured using the comprehensive complication index | within 90 days of admission to hospital | 
| Feasibility of completion of complications at day of discharge | Proportion of patients with a completed comprehensive complication index | within 90 days of admission to hospital | 
| Change in health utility | Measured using EQ-5D-5L (EuroQol- five dimension - five level) | Measurements take at baseline, 5 days post-operatively and 90 days post-operatively | 
| Feasibility of completion of EQ-5D-5L (EuroQol- five dimension - five level) at 90 days | Reported as proportion of respondents replying | 90 days post operatively | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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emergency surgery, malnutrition, pilot study