Oral Hygiene Procedures on Reduction of Oral Malodor

Study Overview
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Brief Summary
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The purpose of the study is to evaluate the effect of various oral hygiene procedures on reduction of oral malodor.

Detailed Description
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Thirty volunteers who matched with including criteria were divided randomly into two groups. Both groups were instructed to brush their teeth with a scrubbing method for the first one week. Then, each group received the different additional oral malodor reduction regimen- in addition to tooth brushing tongue cleaning in one group and chlorine dioxide (ClO2) mouthwash in another group for three consecutive weeks. After that, all the participants were instructed to practice all the three oral hygiene procedures (tooth brushing, mouth washing, tongue cleaning) the last one week. Total volatile sulfur compounds (VSCs) measured by breathtron, tongue coating, plaque score and bleeding on probing (BOP) were outcomes of this study.

Official Title
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Effects of Various Oral Hygiene Procedures on the Reduction of Oral Malodor in Periodontally Healthy Patients

Conditions
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Halitosis

Intervention / Treatment
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* Drug: group 1: drug: chlorine dioxide
* Device: group 2: device: small tooth brush for tongue cleaning


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Clinical diagnosis of oral malodor At least 20 functional teeth No systemic diseases No severe dental diseases Exclusion Criteria: Habit of smoking and betel quid chewing Oral malodor by food and other craniofacial abnormalities Current use of any kind of mouthwash

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 30 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: group 1: drug<br>Drug: group 1: drug: chlorine dioxide 12ml chlorine dioxide (ClO2) mouthwash two times per day, for three consecutive weeks | Drug: group 1: drug: chlorine dioxide<br>* First, each group practiced tooth brushing only for one week. After that each group was requested to do the following procedures. group 1 - additional use of 12ml chlorine dioxide (ClO2) mouthwash two times per day, for three consecutive weeks besides tooth brushing. At last, each group practiced all three methods of tooth brushing, tongue cleaning, mouth washing.<br>* Other names: ClO2Fresh®;|
| Experimental: group 2: device:<br>group 2: device: small tooth brush for tongue cleaning small tooth brush for tongue cleaning | Device: group 2: device: small tooth brush for tongue cleaning<br>* First, each group practiced tooth brushing only for one week. After that each group was requested to do the following procedures. group 2 - additional practice of tongue cleaning by a small tooth brush two times per day, for three consecutive weeks besides tooth brushing. At last, each group practiced all three methods of tooth brushing, tongue cleaning, mouth washing.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Volatile sulfur compounds (VSCs) | Total volatile sulfur compounds was measured by Breathron® | 5 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bleeding on probing | gingival bleeding was recorded of bleeding was detected after examination with periodontal probe. | 5 weeks | 
| Tongue coating | tongue coating was evaluated by Winkel tongue coating index. | 5weeks | 
| Debris index | debris index was evaluated by oral hygiene index. | 5 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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halitosis, chlorine dioxide, tongue cleaning