Patients' Perspective on Radiofrequency Catheter Ablation of AVRT and AVNRT

Study Overview
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Brief Summary
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Atrioventricular nodal reciprocating tachycardia (AVNRT) and atrioventricular reciprocating tachycardia (AVRT) are two similar supraventricular re-entry tachycardias (SVT) emerging in relatively young age in patients without apparent structural heart disease or significant comorbidities. The treatment of choice in those patients is radiofrequency ablation (RFA). The PPRA study is a prospective observational study developed to thoroughly analyze quality of life, utility and willingness-to-pay of Polish patients undergoing RF ablation of AVNRT or AVRT. Based on collected data the investigators will prepare a profile of patient who will benefit most from radiofrequency ablation and who should be scheduled in first place for the ablation in case of problems with accessibility to this service. What is more an analysis of medical and indirect costs of care will be performed.

Official Title
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Patients' Perspective on Radiofrequency Catheter Ablation of AVRT and AVNRT - a Quality of Life, Utility and Willingness to Pay Study (PPRA Study)

Conditions
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Tachycardia, Atrioventricular Nodal Reentry, Re-entrant Atrioventricular Tachycardia

Intervention / Treatment
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* Procedure: RFA


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Written informed consent Age above 18 Scheduled RFA due to AVNRT or AVRT Sufficient knowledge of the Polish language to independently complete the questionnaires Exclusion Criteria: No written informed consent Health states significantly impairing QoL (eg. stroke, advanced heart failure)

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| RFA of AVNRT of AVRT<br> | Procedure: RFA<br>* radiofrequency ablation of slow pathway or accesory pathway<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Health-related quality of life (HRQOL) | Mean score of Patient Perception of Arrhythmia Questionnaire (PPAQ) - a disease-specific QoL questionnaire for patients suffering from supraventricular tachycardia translated and validated according to ISPOR (International Society For Pharmacoeconomics and Outcomes Research) guidelines | two months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Utility of health state | Mean score of EQ-5D - a generic questionnaire measuring a health state utility (official Polish translation) | two months | 
| Medical and indirect cost | Cross-sectional data gathered using original questionnaire designed to measure medical and indiresct costs related to arrhythmia incurred during a year preceding RFA | one year | 
| Willingness-to-pay | a cross-sectional willingness-to-pay questionnaire studying hypothetical situation where RFA was not financed by Polish Health Fund | one day | 
| Effectiveness | Data on medical history, final diagnosis, outcome of treatment, safety and future recommendations | two days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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AVNRT, AVRT, WPW