Cognitive Training in Children With Attention Deficit/ Hyperactivity Disorder (ADHD)

Study Overview
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Brief Summary
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The purpose of this study is to determine the effect of computer program C8 on specific cognitive functions, symptoms and functional outcome compared to treatment as usual in children with ADHD. Furthermore, if the effect is sustained 12 and 24 weeks after training. In addition, it will be investigated, whether younger children benefit more from training than older children.

Official Title
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A Study of the Efficacy of Computerized Cognitive Training on Cognitive Function, Symptoms and Functional Outcome in Children With ADHD.

Conditions
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ADHD

Intervention / Treatment
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* Other: Computer program C8
* Other: Treatment as usual


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: ADHD- diagnosis age 6-13 years Patient has access to computer og internet from home Informed consent Exclusion Criteria: Comorbidity: conduct disorder, autism spectrum disorders, depression, or schizophrenia Head trauma or neurological disease Intelligence quotient (IQ) < 80 Motoric or perceptual handicap Medical disease requiring treatment No informed consent

Ages Eligible for Study
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Minimum Age: 6 Years
Maximum Age: 13 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Computer program C8 + treatment as usual<br>Computer program C 8 + treatment as usual. Subjects in the intervention group will be playing a special computer program C8 for 40 min a day, 6 times a week for 8 weeks in addition to treatment as usual. | Other: Computer program C8<br>* Experimental: Computer program C8 + treatment as usual: Playing a special computer program C8 40 min a day for 6 days a week for 8 weeks.<br>* Other names: Cognitive training;Other: Treatment as usual<br>* Treatment as usual at the clinic<br>* Other names: TAU;|
| Other: Treatment as usual<br>Treatment as usual at the clinic | Other: Treatment as usual<br>* Treatment as usual at the clinic<br>* Other names: TAU;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cambridge Neuropsychological Test Automated Battery (CANTAB): Rapid Visual Information Processing probability of hit. |  | Assesment after the 8 week intervention | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Behavior Rating Inventory of Executive Functions (BRIEF) |  | After the 8 week intervention | 
| ADHD-Rating scale |  | After the 8 week intervention | 
| CANTAB: Attention Switching Task (AST) |  | After the 8 week intervention | 
| Cambridge Neuropsychological Test Automated Battery (CANTAB): Rapid Visual Information Processing |  | After 8 weeks of intervention | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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ADHD