Positive Psychology for Mood Disorders

Study Overview
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Brief Summary
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The investigators are doing this study to see if positive psychology can help adults with depression or bipolar disorder. Positive psychology involves exercises-short tasks-that try to increase good feelings and emotions, like optimism, happiness, personal strengths, and well-being. Positive psychology exercises might include imagining a bright future, being grateful for good events, forgiving others, and doing kind acts for others. The investigators want to see if practicing positive psychology exercises after leaving the hospital can increase feelings of hope, optimism, and positive thinking. The investigators are asking you to take part in this research study because you are in the hospital for depression or bipolar disorder. This research study will compare positive psychology exercises to control condition exercises. During the study, you may take part in control condition exercises instead of positive psychology exercises.

Official Title
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Trial of a Positive Psychology Intervention to Reduce Suicide Risk in Patients With Mood Disorders

Conditions
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Bipolar Disorder, Depression

Intervention / Treatment
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* Behavioral: Positive psychology intervention
* Behavioral: Recollection intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patient admitted to Massachusetts General Hospital Inpatient Psychiatric Unit Age 18 and older Able to read and write in English Admission diagnosis of major depressive disorder or bipolar affective disorder (current depressive episode), confirmed using the Mini International Neuropsychiatric Interview and inpatient chart review Exclusion Criteria: Psychotic symptoms, as assessed using the Mini International Neuropsychiatric Interview and inpatient chart review Cognitive disorder, assessed using a six-item cognitive screen developed for research Primary admission diagnosis of substance use disorder

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Positive psychology intervention<br>4-week positive psychology intervention of 1 positive psychology exercise per week. Exercises will include 1) recalling 3 good events, 2) writing a letter of thankfulness, 3) using a personal strength, 4) envisioning a best possible future. | Behavioral: Positive psychology intervention<br> <br> |
| Active Comparator: Recollection intervention<br>4-week recollection intervention of 1 recollection exercise per week. Exercises will include recalling events related to 1) daily activities, 2) health, 3) social life, 4) morning and evening. | Behavioral: Recollection intervention<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Feasibility of positive psychology exercises | Feasibility will be measured by: Completion rate of exercises Ease of exercises (rated on a 5-point scale) Helpfulness of exercises (rated on a 5-point scale) | 8 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Impact of positive psychology exercises on positive affect | Positive affect will be measured by: Optimism score on the Life Orientation Test-Revised (scores range from 3 to 30, with higher scores indicating higher levels of optimism) Gratitude score on the Gratitude Questionnaire-6 (scores range from 6 to 42, with higher scores indicating higher levels of gratitude) Positive emotion score on the Positive and Negative Affect Scale (scores range from 10 to 50, with higher scores indicating higher levels of positive emotion) | 8 weeks | 
| Impact of positive psychology exercises on negative affect | Negative affect will be measured by: Hopelessness scores on the Beck Hopelessness Scale (scores range from 0 to 20, with higher scores indicating higher levels of hopelessness). Suicidal ideation scores on the Concise Health Risk Tracking scale (scores range from 12 to 60, with higher scores indicating higher levels of suicidal ideation) Depression scores on the Quick Inventory of Depressive Symptomatology-Self Report (scores range from 0 to 27, with higher scores indicating higher levels of depression) | 8 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Bipolar disorder, Depression, Positive psychology