Prevalence of a Phenomenon of Epic Dream Disorder

Study Overview
=================
Brief Summary
-----------------
A single-center, cross-sectional, non-interventional study based on the sleep department of the Kozhevnikov Clinic for Nervous Diseases at Sechenov University. A.Y. Kozhevnikov Sechenov University is being conducted between September 2022 and December 2023 to assess the prevalence and associated symptoms and risk factors of a multiple dreams with vivid emotion, causing morning and daytime symptoms - phenomenon of Epic Dream Disorder (EDD). Demographic, sleep and psychological characteristics of people with multiple dreams will be identified, including the following standardized scales: Spielberger Anxiety Scale, Beck Depression Scale, Shortened Sleep Questionnaire. Data will be collected by mean of online questionnaire tool. According to the data obtained, prevalence of the phenomenon, differences between continuous, rank and categorical variables will be calculated in participants with and without EDD. Multivariate logistic regression will be performed to assess associated risk factors of EDD.

Detailed Description
-----------------
In clinical practice, there are patients complaining for numerous dreams, which negatively affect the daytime well-being of patients, although these complaints do not fall into the category of nightmares. There are currently no data on the prevalence of the phenomenon of this phenomenon. Studies conducted on small groups of patients have found that they are more likely to have chronic pain syndrome, family history of their complaints. The proposed study will be able to provide the first data on the prevalence and concomitant symptoms of multiple dreams. This will allow the authors to give a more precise definition of this phenomenon, describe its concomitant symptoms, and evaluate the relevance of its diagnosis and treatment. The results of the study will set the stage for further clinical research on the pathogenesis and therapy approaches. The further studies are needed to explain the causes of this phenomenon to the patients and provide them with the necessary assistance. In view of the high workload of the medical staff, and clinical centers under the COVID-19 pandemic, and in order to increase convenience for both study participants and the researchers, data for this study will be collected remotely. The implementation of the study objectives did not require a face-to-face examination of the participants. Internet-based data collection will further simplify the processing of the data. This approach to conducting the study has already shown its applicability in a number of clinical trials. The study will be conducted at the I.M. Sechenov First Moscow State Medical University, Russian Ministry of Health, UTH No. 3, Clinic of Nervous Diseases. A.Y. Kozhevnikov, Department of Sleep Medicine. This study plans to inсlude all participants who agreed to participate (i.e., who clicked on the button agree after reading informed consent form). Information about the study and link to the questionnaires and informed consent form will be spreaded in social media, student communities, and university departmental staff communities The demographic, sleep, and psychological characteristics of people with multiple dreams will be assessed. Then a statistical analysis will be performed to compare the differences in rank, continuous, and categorical variables, and perform a multivariate logistic regression.

Official Title
-----------------
Assessing the Prevalence and Associated Risk Factors of a Phenomenon of Epic Dream Disorder: a Cross-sectional Study

Conditions
-----------------
Dream Disorder

Intervention / Treatment
-----------------
* Diagnostic Test: Online questionnaire


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: consent to participate in the study, expressed by ticking the appropriate box on the website after reading the text of the informed consent, confirming their understanding of the study and their consent to participate in it; Exclusion Criteria: age < 18 years; This criterion is evaluated when completing the questionnaire, questionnaires from participants under 18 years old will not be included in the statistical analysis

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| study group<br>all participants older than 18 years who agreed to participate (i.e., who clicked on the button agree after reading informed consent form) with no regard to sex, race, education, family status | Diagnostic Test: Online questionnaire<br>* data will be collected remotely on the online platform Qualtrics<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prevalence of the phenomenon of epic dream disorder | prevalence of the disease - the proportion of participants with the diagnosed epic dream disorder to the whole sample | Through study completion, an average of 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Demographic outcomes: Sex | options (male, female) | Through study completion, an average of 1 year | 
| Demographic outcomes: Age | Age in years | Through study completion, an average of 1 year | 
| Demographic outcomes: Weight | Weight in kg | Through study completion, an average of 1 year | 
| Demographic outcomes: Height | Height in cm | Through study completion, an average of 1 year | 
| Demographic outcomes: Level of education | choose category for the level of education | Through study completion, an average of 1 year | 
| Demographic outcomes: name the University | For students only | Through study completion, an average of 1 year | 
| Demographic outcomes: name your department | For students only | Through study completion, an average of 1 year | 
| Demographic outcomes: year of study | For students only | Through study completion, an average of 1 year | 
| Demographic outcomes: Employment status | choose category for the employment status and specify your scope of activities if any | Through study completion, an average of 1 year | 
| use of nicotine | Fact and frequency of use of nicotine | Through study completion, an average of 1 year | 
| use of alcohol | Fact and frequency of use of alcohol | Through study completion, an average of 1 year | 
| Medical history | Presence of any chronic illnesses (specify the name) | Through study completion, an average of 1 year | 
| duration of complaints | Question: how long do you experience multiple dreams | Through study completion, an average of 1 year | 
| Average duration of sleep | hours | Through study completion, an average of 1 year | 
| dreams during daytime nap | Presence of dreams during daytime nap (yes or no) | Through study completion, an average of 1 year | 
| Amount of dreams during the night | specify number (0, 1, 2, 3 and more) | Through study completion, an average of 1 year | 
| discomfort after the night of active dreaming | Presence of discomfort after the night of active dreaming in the morning or during the day | Through study completion, an average of 1 year | 
| triggers of active dreaming | Were you able to identify a factor or event that triggered the appearance of multiple dreams? If yes, specify. | Through study completion, an average of 1 year | 
| Intensity of thought activity in dream | range 1-5 | Through study completion, an average of 1 year | 
| Intensity of speech activity in dream | range 1-5 | Through study completion, an average of 1 year | 
| Intensity of running in dream | range 1-5 | Through study completion, an average of 1 year | 
| Intensity of walking in dream | range 1-5 | Through study completion, an average of 1 year | 
| Intensity of monotonous physical movements in dream | range 1-5 | Through study completion, an average of 1 year | 
| Intensity of flight in dream | range 1-5 | Through study completion, an average of 1 year | 
| Intensity of swimming in dream | range 1-5 | Through study completion, an average of 1 year | 
| Intensity of jumping in dream | range 1-5 | Through study completion, an average of 1 year | 
| Intensity of trip by transport in dream | range 1-5 | Through study completion, an average of 1 year | 
| recalling dreams upon awakening | Question: After waking up, do you remember what you saw in the dream? with 3 options - I remember that I had a dream, but I don't remember what it was about I remember what the dream was about I remember all the details of the dream | Through study completion, an average of 1 year | 
| characteristics of dream content | Intensity of positive emotions (range 1-5) | Through study completion, an average of 1 year | 
| characteristics of dream content | Intensity of negative emotions (range 1-5) | Through study completion, an average of 1 year | 
| Impression that your brain stays awake while you sleep | range 1-5 | Through study completion, an average of 1 year | 
| Any peculiarities of your dream | specify | Through study completion, an average of 1 year | 
| Awareness of a dream | I don't realize I'm dreaming; I am aware that I am dreaming, but I have no control; Awareness of dreaming and controlling; I realize that I'm dreaming and I can change the plot | Through study completion, an average of 1 year | 
| Subjective symptoms in the morning after a night of active dreaming | Presence and length of the symptome Having difficulty knowing whether something happened in the dream or in reality | Through study completion, an average of 1 year | 
| Subjective symptoms in the morning after a night of active dreaming | Presence and length of the symptom the feeling you had in the dream persists during the wakefulness for more than a few seconds | Through study completion, an average of 1 year | 
| Subjective symptoms in the morning after a night of active dreaming | Presence and length of the symptom Heart palpitations | Through study completion, an average of 1 year | 
| Subjective symptoms in the morning after a night of active dreaming | Presence and length of the symptom Shortness of breath | Through study completion, an average of 1 year | 
| Subjective symptoms in the morning after a night of active dreaming | Presence and length of the symptom Hyperhidrosis | Through study completion, an average of 1 year | 
| Subjective symptoms in the morning after a night of active dreaming | Presence and length of the symptom feeling Cold | Through study completion, an average of 1 year | 
| Subjective symptoms in the morning after a night of active dreaming | Presence and length of the symptom Fatigue | Through study completion, an average of 1 year | 
| Subjective symptoms in the morning after a night of active dreaming | Presence and length of the symptom Bad mood | Through study completion, an average of 1 year | 
| Subjective symptoms in the morning after a night of active dreaming | Presence and length of the symptom Muscle pain | Through study completion, an average of 1 year | 
| Subjective symptoms in the morning after a night of active dreaming | Presence and length of the symptom Headache | Through study completion, an average of 1 year | 
| Subjective symptoms in the morning after a night of active dreaming | Presence and length of the symptom Pain in chest | Through study completion, an average of 1 year | 
| Subjective symptoms in the morning after a night of active dreaming | Presence and length of the symptom Balance disturbance | Through study completion, an average of 1 year | 
| Subjective symptoms in the morning after a night of active dreaming | Presence and length of the symptom Loss of tactile sensitivity | Through study completion, an average of 1 year | 
| Subjective symptoms in the morning after a night of active dreaming | Presence and length of the symptom Tingling/frowning sensation | Through study completion, an average of 1 year | 
| Subjective symptoms in the morning after a night of active dreaming | Presence and length of the symptom Anxiety | Through study completion, an average of 1 year | 
| Subjective symptoms in the morning after a night of active dreaming | Presence and length of the symptom Weakness | Through study completion, an average of 1 year | 
| Subjective symptoms in the morning after a night of active dreaming | Presence and length of the symptom Nausea | Through study completion, an average of 1 year | 
| Subjective symptoms in the morning after a night of active dreaming | Presence and length of the other symptoms, if any | Through study completion, an average of 1 year | 
| Use of medications | Question about the use of medication, no or yes (specify the name) | Through study completion, an average of 1 year | 
| Dose of medications | Question about the dose of medication, if any | Through study completion, an average of 1 year | 
| Frequency of medications | Question about the frequency of medications use, if any | Through study completion, an average of 1 year | 
| awakenings during the night | Number of awakenings during the night | Through study completion, an average of 1 year | 
| Frequency of nights with multiple dreams | Number of nights per week | Through study completion, an average of 1 year | 
| Seasonal fluctuation of the multiple dreams | During which season do the multiple dreams occur more often | Through study completion, an average of 1 year | 
| Family history of Excessive dream disorder | Did any of your family members has the same complaints, if yes, specify | Through study completion, an average of 1 year | 
| Depression symptoms | Beck Depression scale | Through study completion, an average of 1 year | 
| State anxiety symptoms | State anxiety by Spielberger Anxiety Scale | Through study completion, an average of 1 year | 
| Trait anxiety symptoms | Trait anxiety by Spielberger Anxiety Scale | Through study completion, an average of 1 year | 
| Shortened Sleep Questionnaire | Validated questionnaire to evaluate insomniac complaints, parasomnias, use of medications, hypersomnias, sleep related breathe disorders | Through study completion, an average of 1 year | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
dream, epic dream disorder, daytime symptoms