Correlation Between Preeclampsia and Positive for Obstructive Sleep Apnea Screening Test: STOPBANG Questionnaire

Study Overview
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Brief Summary
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The purpose of this study is to find the correlation between high risk OSA (obstructive sleep apnea) patient, based on Stop-bang screening tool and preeclampsia

Detailed Description
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Obstructive sleep apnea (OSA) has been associated with preeclampsia and intrauterine growth retardation (IUGR). Since the gold standard diagnosis of OSA is polysomnogram which is limited by cost and availability. Therefore, various screening tools were proposed in order to identify high risk OSA patient such as Stop-bang questionnaire. From the previous study, Stop-bang showed a high predictive performance and the score equal or higher than 3 determines high risk for OSA.

Conditions
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Sleep Apnea, Obstructive

Intervention / Treatment
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* Other: Preeclampsia positive


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: - Pregnant women who were scheduled for cesarean delivery or admitted to the antepartum unit at Ramathibodi hospital Exclusion Criteria: Age < 18 year old Previous diagnose OSA Patients who have used continuous positive airway pressure (CPAP) or bi-level positive airway pressure (Bi-PAP) fro OSA treatment

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| High risk for OSA<br>High risk OSA defines as Stop-bang score ≥ 3 | Other: Preeclampsia positive<br> <br> * Other names: Preeclampsia negative;|
| Low risk for OSA<br>Low risk OSA defines as Stop-bang score < 3 | Other: Preeclampsia positive<br> <br> * Other names: Preeclampsia negative;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prevalence of pre-eclampsia between high and low risk of OSA patient based on Stop-bang screening test |  | 1 day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| prevalence of pre-eclampsia between high and low risk of OSA patient, based on Epworth sleepiness scale |  | 1 day | 
| prevalence of pre-eclampsia between high and low risk of OSA patient, based on Berlin questionnaire |  | 1 day | 
| prevalence of pre-eclampsia between high and low risk of OSA patient, based on American society check list |  | 1 day | 
| The prevalence of maternal adverse event between high risk and low risk of OSA patient | Maternal adverse events include hypoxemia, arrythmia, perioperative myocardial infarction, heart failure | 1 day | 
| The prevalence of neonatal adverse event between high risk and low risk of OSA patient | Neonatal adverse events include IUGR, neonatal intensive care unit admission, low apgar score | 1 day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Obstructive sleep apnea, Preeclampsia, Pregnancy, Stopbang