Increasing Activity in Liver Transplant Patients

Study Overview
=================
Brief Summary
-----------------
Will adult liver transplant patients who are provided with physical activity (walking) instructions increase their physical activity and perceive an improved quality of life?

Official Title
-----------------
Increasing Physical Activity in Post Liver Transplant Patients

Conditions
-----------------
Liver Transplant

Intervention / Treatment
-----------------
* Behavioral: Physical activity


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion criteria: Adult patients 18-65 years of age who receive a liver transplant at Mayo Clinic Jacksonville. Adult patients who are 5-21 days post liver transplant. Must be followed by Mayo Clinic Jacksonville at 4 months postoperatively. Approved by a hepatologist and/or transplant surgeon to participate. Exclusion criteria: Patients with active infections Patients with encephalopathy or cognitive dysfunction Patients who receive a combined liver-kidney transplant Patients with severe debility Patients who require assistance to ambulate.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Liver Transplant Patients<br>Participants will be provided physical activity walking instructions and asked to record their daily activity on an activity log. | Behavioral: Physical activity<br>* Participants will be provided physical activity walking instructions and asked to record their daily activity on an activity log. Participants will be given the International Physical Activity Questionnaire and asked about their quality of life at baseline, at 6 weeks and at 4 months.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Physical Activity Measured by the International Physical Activity Questionnaire (IPAQ) | The IPAQ calculates the metabolic equivalent (MET) score by asking participants the days and minutes exercised in three categories of intensity (vigorous, moderate, and walking) during the previous one week. The following formula is used to calculate the MET: MET=8(vigorous activity) (minutes) + 4 (moderate activity)(minutes) +3.3 (walking activity) (minutes). | Baseline, 6 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Quality of Life at Baseline, 6 Weeks, and 4 Months | Participants reported their perceived quality of life using a scale 1 - 10, with 1 being the worst and 10 being the best. | Baseline, 6 weeks, 4 months | 
| Number of Patients Who Document Their Physical Activity | 8 participants documented their physical activity at 6 weeks. 6 participants documented their physical activity at 4 months. | Baseline to 6 weeks, repeated measure at 4 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Liver transplant, Physical Activity, Quality of Life