Psychometric Validation of the Competitive Attention Test

Study Overview
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Brief Summary
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This project aims at validating a new neuropsychological test to measure voluntary and involuntary attention for clinical use to diagnose attentional deficits. This project proposes: a test-retest procedure in healthy subjects aged from 6 to 90 year-old; testing in attention deficit hyperactivity disorder (ADHD) patients before psychostimulant treatment; testing in attention deficit hyperactivity disorder (ADHD) patients before psychostimulant treatment.

Official Title
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Psychometric Validation of the Competitive Attention Test (CAT) : Simultaneous and Separated Measures of Voluntary and Involuntary Attention

Conditions
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Attention Deficit Hyperactivity Disorder

Intervention / Treatment
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* Other: experience 1 : Competitive attention test in healthy participants
* Other: experience 2 : Competitive attention test in patients with ADHD with no treatment
* Other: experience 3 :Competitive attention test in patients with ADHD with psychostimulant treatment


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: healthy major participants: Age from 18 to 90 year-old Informed consent to participate in the study No neurological or psychiatric disorder No history of neuro-psychiatric disorder or neurodevelopmental type dysphasia, dyslexia, dyspraxia, attention deficit disorder healthy minor participants: Age from 6 to 17 year-old Informed consent of parents or guardians for the child's participation in the study No neurological or psychiatric disorder No history of neuro-psychiatric disorder or neurodevelopmental type dysphasia, dyslexia, dyspraxia, Attention deficit disorder ADHD minor patients: Age from 6 to 17 year-old Informed consent of parents or guardians for the child's participation in the study ADHD Diagnosis with or without hyperactivity No psychiatric history other than ADHD. For Experience 3: treatment in progress. Exclusion Criteria: healthy major participants Age below 18 or above 90 year-old unaffiliated or non-beneficiaries of the social security scheme healthy minor participants: Age below 6 or above 18 year-old unaffiliated or non-beneficiaries of the social security scheme ADHD minor patients: Age below 6 or above 18 year-old unaffiliated or non-beneficiaries of the social security scheme

Ages Eligible for Study
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Minimum Age: 6 Years
Maximum Age: 90 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Healthy participants aged from 6 to 90 year-old<br> | Other: experience 1 : Competitive attention test in healthy participants<br>* Comparison of behavioral measures (reaction times and percentage of correct responses) obtained twice with the CAT test in healthy participants (2 to 6 weeks apart).<br>|
| Experimental: patients with ADHD with no treatment<br>patients with ADHD aged from 6 to 90 year-old with no treatment | Other: experience 2 : Competitive attention test in patients with ADHD with no treatment<br>* Behavioral (reaction times and percentage of correct responses) and Electroencephalography (EEG) measures obtained with the CAT test in patients with ADHD with no treatment.<br>|
| Experimental: patients with ADHD with treatment<br>patients with ADHD aged from 6 to 90 year-old with psychostimulant treatment (Methylphenidate) | Other: experience 2 : Competitive attention test in patients with ADHD with no treatment<br>* Behavioral (reaction times and percentage of correct responses) and Electroencephalography (EEG) measures obtained with the CAT test in patients with ADHD with no treatment.<br>Other: experience 3 :Competitive attention test in patients with ADHD with psychostimulant treatment<br>* Behavioral (reaction times and percentage of correct responses) and EEG measures obtained with the CAT test in patients with ADHD before and after psychostimulant treatment.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Reaction times in healthy subjects and patients with ADHD. | Reaction times in milliseconds obtained with the CAT test in healthy participants and in patients with ADHD. | 6 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Percentage of correct responses in healthy subjects and patients with ADHD. | Percentage of correct responses obtained with the CAT test in healthy participants and in patients with ADHD. | 6 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Attention Deficit Hyperactivity Disorder, attention, distraction, psychometric test, neuropsychological test validating procedure, psychostimulant