linjc16/ctgov huggingface dataset:
An Algorithm for Predicting Blood Loss and Transfusion Risk in Fast Track Total Hip Arthroplasty

Study Overview
=================
Brief Summary
-----------------
Aim of these study is to create an algorithm, using data from patients that undergoing total hip arthroplasty, to predict blood loss after surgery and permit a safe domestic discharge.

Detailed Description
-----------------
Two different cohorts of patients undergoing total hip arthroplasty will be analyzed to obtain data about hemoglobin trends. The first group will be used to obtain the algorithm, the second one to validate results of the first group, determining sensitivity and specificity.

Official Title
-----------------
An Algorithm for Predicting Blood Loss and Transfusion Risk in Fast Track Total Hip Arthroplasty

Conditions
-----------------
Total Hip Replacement, Blood Loss

Intervention / Treatment
-----------------
* Procedure: Total hip arthroplasty, blood loss analysis


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with hip arthritis Exclusion Criteria: ASA 4 - 5 Active treatment with warfarin Coagulation disorders
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Analysis group<br>Create an algorithm to predict blood loss using patients data | Procedure: Total hip arthroplasty, blood loss analysis<br>* Data analysis about blood loss in total hip replacement<br>|
| Control group<br>The algorithm was applied to analyze sensitivity and specificity | Procedure: Total hip arthroplasty, blood loss analysis<br>* Data analysis about blood loss in total hip replacement<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Create an algorithm to predict blood loss after total hip arthroplasty | Data from the fist cohort of patients have been collected and analyzed to obtain an algorithm describing the trends of hemoglobin values after total hip arthroplasty. These algorithm was after applied to patients of a second cohort of consecutive patients undergoing total hip arthroplasty to determine specificity and sensitivity. | 3 months |
Potential Acceptance of COVID-19 Vaccines in Healthcare Workers in Egypt

Study Overview
=================
Brief Summary
-----------------
The COVID-19 pandemic is expected to remain as a public health threat and economic burden all over the world. The available proposed vaccines are still lacking large randomized controlled trials testing its efficacy and safety. Thus, the acceptance of vaccination between citizens as well as healthcare workers is not guaranteed. As the vaccine is starting to be distributed the acceptance of healthcare givers should be measured as they are usually the front line facing the problem and they have a responsibility to explain the need of immunization to the rest of population. Strategies to enhance the acceptance and trust of the available vaccines may be needed.

Official Title
-----------------
A National Survey of Potential Acceptance of COVID-19 Vaccines in Healthcare Workers in Egypt

Conditions
-----------------
Covid19

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Healthcare workers - Exclusion Criteria: None healthcare workers

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Measure frequency of acceptance of vaccination | number of healthcare worker agreeing to take the vaccine | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Describe causes of refusal of vaccination | answer a questionnaire of the causes of avoidance of vaccine | 6 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
COVID-19, Healthcare workers, COVID-19 vaccines, Vaccine, Acceptance
A Single Dose, 4-Period, 2-Treatment Replicate Design Bioequivalency Study of Granisetron Hydrochloride 1 mg Tablets Under Fasting Conditions

Study Overview
=================
Brief Summary
-----------------
The objective of this study was to assess bioequivalence of a potential generic 1 mg granisetron tablet formulation compared with Roche Laboratories' 1 mg granisetron tablet, Kytril, following a single 1 mg dose, under fasting conditions.

Official Title
-----------------
A Single Dose, 4-Period, 2-Treatment Replicate Design Bioequivalency Study of Granisetron Hydrochloride 1 mg Tablets Under Fasting Conditions

Conditions
-----------------
Nausea, Vomiting

Intervention / Treatment
-----------------
* Drug: Granisetron


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: No clinically significant abnormal finding on the physical examination, medical history, or clinical laboratory results during screening. Exclusion Criteria: Positive test for HIV, Hepatitis B, or Hepatitis C. Treatment with known enzyme altering drugs. History of allergic or adverse response to granisetron or any other comparable or similar drug.

Ages Eligible for Study
-----------------
Minimum Age: 19 Years
Maximum Age: 45 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: Granisetron|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bioequivalence |  | Baseline, four period, 7 day washout | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Prevention of nausea and vomiting associated with radiation or chemotherapy
Heel Cushion for Plantar Fasciitis

Study Overview
=================
Brief Summary
-----------------
The investigators study aim to evaluate the efficacy of PSU heel cushion in treatment of plantar fasciitis. The investigators will do a randomized controlled trial in patient with plantar fasciitis compared with stretching exercise alone. The outcome measurement include heel pain improvement, compliance, satisfaction, foot functional score at 6 months.

Official Title
-----------------
PSU Heel Cushion for Treatment of Plantar Fasciitis:A Randomized Controlled Trial

Conditions
-----------------
Plantar Fasciitis

Intervention / Treatment
-----------------
* Device: PSU heel cushion and plantar fascia specific stretching exercise


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patient with plantar fasciitis Exclusion Criteria: Rheumatologic problem such as rheumatoid arthritis Latex allergy Pregnancy Previous surgery around foot and ankle

Ages Eligible for Study
-----------------
Minimum Age: 15 Years
Maximum Age: 60 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Plantar fascia stretching exercise<br>Patient perform plantar fascia stretching 3 times per day | Device: PSU heel cushion and plantar fascia specific stretching exercise<br>* Wear heel cushion during daily activity Plantar fascia stretching exercise 3 times per day<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| VAS score |  | 2 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Compliance |  | 2 years | 
| Satisfaction score |  | 2 years | 
| Foot functional score : FHSQ score |  | 2 years | 
| Number of rescue pain killer |  | 2 years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
plantar fasciitis, heel cushion, treatment
Prophylactic Antibiotics on Urethral Catheter Withdrawal

Study Overview
=================
Brief Summary
-----------------
Urinary-tract infection (UTI) is the most common type of hospital-acquired infection (30% of all). The purpose of this study is to determine whether antibiotic prophylaxis for urinary catheter removal is useful at preventing catheter-associated urinary-tract infection.

Detailed Description
-----------------
Urinary-tract infection (UTI) is the most common type of hospital-acquired infection (30% of all). The researchers undertake a double-blind, placebo-controlled trial to assess the efficacy of single-dose therapy of trimethoprim-sulfamethoxazole or ciprofloxacin, versus placebo therapy in selected groups of surgical patients who had bladder drainage scheduled to last longer than 3 days.

Official Title
-----------------
Use of Antibiotic Prophylaxis on Urethral Catheter Withdrawal: A Randomized Double-Blind Placebo-Controlled Trial

Conditions
-----------------
Urinary Tract Infection, Bacteriuria

Intervention / Treatment
-----------------
* Drug: trimethoprim-sulfamethoxazole
* Drug: ciprofloxacin


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Urethral catheter in situ for at least 3 days (72h) Exclusion Criteria: Pregnancy Impaired renal or hepatic function (serum creatinine > 150 mmol/l, serum transaminases > 75 IU/l) Fever Symptomatic urinary tract infection Antibiotic use ≤ 48 hours before urinary catheter removal Allergy to trimethoprim-sulfamethoxazole or ciprofloxacin Urologic pathology

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: trimethoprim-sulfamethoxazole|nan|
|Drug: ciprofloxacin|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Symptomatic bacteriuria |  |  | 
| Asymptomatic bacteriuria |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Antibiotic resistance patterns |  |  | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Bacteriuria, Urinary Catheter, Urinary tract infection, Prophylaxis, Urinary catheter removal
National Covid-19 Surveillance Physicians

Study Overview
=================
Brief Summary
-----------------
The investigators will analyze the presence of antibodies against SARS-COV2 in physicians working in emergency and intensive care medicine and in those who treat Covid 19 patients.

Official Title
-----------------
National Covid-Surveillance Physicians

Conditions
-----------------
Antibody COVID-19

Intervention / Treatment
-----------------
* Diagnostic Test: Antibody test (SARS-CoV2)


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Qualified as physician Exclusion Criteria: none

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 99 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: Antibody test (SARS-CoV2)|Antibody test|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Presence of antibodies against SARS-COV2 |  | 3 months |
Effects of Psychoeducation of Relatives to Patients With Serious Mental Illness

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to determine the effects of psychoeducation for relatives to patients with serious mental illness.

Detailed Description
-----------------
The main aim of the study is to compare the effects of group psychoeducation for relatives to patients with serious mental illness with a waiting list control group. The main hypothesis is whether psychoeducation in groups has effects on the stress experience and coping style in the relatives. The relatives will receive group education in 6 weekly sessions. We will measure stress experience, coping style and the relatives' health condition before the sessions, after the sessions and at one year follow-up.

Official Title
-----------------
Effects of Psychoeducation of Relatives to Patients With Serious Mental Illness

Conditions
-----------------
Mental Disorder, Depressive Disorder, Schizophrenia

Intervention / Treatment
-----------------
* Behavioral: Psychoeducation


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Relatives to patients having a psychotic or bipolar disorder Good Norwegian language skills Consent to participate The patients' consent for their relatives to participate

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 1 S+E<br>Relatives of patients with schizophrenia, who receive education | Behavioral: Psychoeducation<br>* Structured disorder-related educational program for relatives<br>|
| No Intervention: 2 S-E<br>Relatives of patients with schizophrenia, who do not receive education | |
| Experimental: 3 B+E<br>Relatives of patients with bipolar disorder, who receive education | Behavioral: Psychoeducation<br>* Structured disorder-related educational program for relatives<br>|
| No Intervention: 4 B-E<br>Relatives of patients with bipolar disorder, who do not receive education | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| ECI (Experience of Caregiving Inventory) (Smuckler et al,1994) |  | 0-6 months | 
| COOP/WONCA (Bowling, 1995) |  | 0-6 months | 
| Selection of questions from COPE (Carver et al. 1989) |  | 0-6 months | 
| Evaluation-questions |  | 0-6 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Family, Coping Skills, Psychoeducation, Stress, Psychological, Health Education
Global Sinus Surgery Registry

Study Overview
=================
Brief Summary
-----------------
This study evaluates long-term safety and effectiveness of primary sinus surgery in a real-world population of adults with chronic rhinosinusitis (CRS) or recurrent acute rhinosinusitis (RARS). This post-market study will evaluate sinus surgery performed using commercially available sinus instrumentation (e.g. sinus balloon catheters, powered microdebriders, manual instruments).

Official Title
-----------------
OASIS Global Sinus Surgery Registry

Conditions
-----------------
Chronic Rhinosinusitis, Recurrent Acute Rhinosinusitis

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age ≥ 18 years or minimum adult age as required by local regulations The subject has a planned primary sinus surgery, which includes either traditional transnasal endoscopic sinus surgery (ESS), balloon sinus dilation (BSD) or a hybrid procedure Subjects diagnosed by ENT surgeon with chronic rhinosinusitis (CRS) or recurrent acute rhinosinusitis (RARS) per AAO-HNS or EPOS adult sinusitis clinical practice guidelines The subject has been informed of the nature of the registry and has consented to participate and authorized the collection and release of medical information by signing a consent form Subject is able to read and understand local language Exclusion Criteria: Prior sinus surgery. Septoplasty, Nasal Polypectomy, Septorhinoplasty, Nasal Valve and Turbinate Reduction surgeries are not exclusions Planned surgery of any of the following : orbital decompression, skull base, neoplasm, lacrimal, UPPP, aesthetic surgery, Potts Puffy tumor, Draf III Planned external approaches (i.e. not trans-nasal) Planned off-label usage of balloon sinus dilation products. Balloon sinus dilation performed with a non-Acclarent balloon product

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of Participants Completing Follow-Up Visits |  | 2 years |
Prevalence of Auditory Dysfunction and ICU-acquired Delirium Following Cardiac Surgery With Cardiopulmonary Bypass: a Prospective Observational Study

Study Overview
=================
Brief Summary
-----------------
AUDICS-ICU is a prospective observational aiming to evaluate the prevalence of auditive dysfunction following cardiac surgery. Participants will undergo audiometric testings before and 3 months after cardiac surgery with cardiopulmonary bypass. Furthermore, the study evaluates hearing loss-associated ICU-acquired delirium after cardiac surgery with cardiopulmonary bypass.

Official Title
-----------------
Prevalence of Auditory Dysfunction and ICU-acquired Delirium Following Cardiac Surgery With Cardiopulmonary Bypass: a Prospective Observational Study

Conditions
-----------------
Hearing Loss, Cardiac Surgery, Cardiopulmonary Bypass, Postoperative Cognitive Dysfunction, Delirium

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Over 18 years old Undergoing non urgent cardiac surgery with cardiopulmonary bypass Exclusion Criteria: Pregnant History of ear surgery Ear disease Inadequate understanding of the protocol

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prevalence of auditive dysfunction following cardiac surgery with cardiopulmonary bypass | Change from baseline audiometric testings at 3 months after cardiac surgery with cardiopulmonary bypass | 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| ICU-acquired delirium | Diagnose by CAM-ICU scale during ICU stay (if positive meaning the patient has delirium, CAM-ICU negative meaning the patient doesn't have delirium) | 7 days | 
| Cerebral perfusion | Near infrared spectroscopy during per operative period and transcranial doppler during ICU stay | 7 days | 
| Patient's quality of life after cardiac surgery: Survey | Survey evaluation quality of life at the end of ICU stay (IPREA) and 3 months after surgery. On a scale from 0 (best quality of life) to 100 (low quality of life) | 3 months |
Validation of a Questionnaire for Measuring Quality of Life in Patients With Chronic Inflammation of the Middle Ear

Study Overview
=================
Brief Summary
-----------------
For measuring quality of life in patients with chronic inflammation of the middle ear, only two questionnaires currently exist. However, these questionnaires are designed only to measure either disease-specific health or hearing-related quality of life. The aim of this project is the validation of a pre-existing comprehensive questionnaire, which is routinely administered in the investigators clinic but has never been validated. Following a retrospective item reduction based on existing data, this questionnaire will be prospectively validated. Applying the resulting questionnaire in future studies on chronic middle ear inflammation, not only objective outcome parameters (e.g. audiograms) but also quality of life will be assessed. Therefore, the investigators questionnaire will add substantial information to these outcome studies by providing a subjective outcome parameter.

Official Title
-----------------
Validation of a Questionnaire for Measuring Health-related Quality of Life in Patients With Chronic Otitis Media

Conditions
-----------------
Chronic Otitis Media

Intervention / Treatment
-----------------
* Other: Administration of questionnaire


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: clinical diagnosis of chronic otitis media Exclusion Criteria: none

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| questionnaire<br> | Other: Administration of questionnaire<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Validity | Several aspects of Validity will be determined by different methods: content validity is made certain by construction procedure of the questionnaire (e.g. involving of specialists and patients) construct validity by factor analysis criterion validity by correlating a global question with the overall questionnaire score | day 1 (day of consultation) |