Impact of Local Anesthesia on Postbronchoscopy Fever: a Randomised Controlled Study

Study Overview
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Brief Summary
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Impact of Local Anesthesia on Postbronchoscopy Fever: a Randomised Controlled Study

Detailed Description
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Fiberoptic bronchoscopy (FOB) is the essential procedures for diagnosis and treatment of respiratory diseases。 Fever following FOB has been frequently reported. Fever is usually caused by patient discomfort and delay recovery from illness, or even worse. The reported frequency of this complication ranges from 1 to 20%. According to previous reports, postbronchoscopy fever is associated with advanced age, the presence of abnormal bronchoscopic findings,documented endobronchial obstruction, bronchoscopic intervention for malignancy, BAL, bronchial brushing, endotoxin contamination during bronchoscopy, instillation of topical anesthetic through the bronchoscope, abnormal differential cell counts in the BAL fluid (BALF), bacterial growth in the BALF culture,and the severity of bleeding. At present, guidelines recommend sedation and analgesia combined with airway surface anesthesia for Fiberoptic bronchoscopy. laryngeal spray and cricothyroid anesthesia often used in clinical.Cricothyroid local anesthesia has a good effect, but it is an invasive operation, this is risk factors for fever after bronchoscopy.Therefore, to compare fever in the two kinds of airway anesthesia on Bronchoscopy . So as to provide the local anesthesia method with little influence on the patient.

Official Title
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Impact of Local Anesthesia on Postbronchoscopy Fever: a Randomised Controlled Study

Conditions
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Postoperative Complications

Intervention / Treatment
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* Other: local surface anesthesia
* Device: Laryngeal tube


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: ASA I-III Exclusion Criteria: use of immunosuppressive agents or corticosteroids body temperature 37.3°C during the 24 h prior to FOB,intubation or mechanical ventilation therapeutic bronchoscopy (foreign body removal, bronchial toilet, or stenting), discharge within 24 h of FOB surgical or diagnostic procedures within 24 h of FOB.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Cricothyroid<br>local surface anesthesia by Cricothyroid | Other: local surface anesthesia<br>* Airway anesthesia for Bronchoscopy<br>|
| Experimental: Laryngeal tube<br>local surface anesthesia by Laryngeal tube | Other: local surface anesthesia<br>* Airway anesthesia for Bronchoscopy<br>Device: Laryngeal tube<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Fever | Fever was defined as an axillary body temperature 37.3°C | 48 hour |