Comparison of the Accuracy of Non-invasive Hemoglobin Measurement (SpHb) and Vena Cava Inferior Ultrasound

Study Overview
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Brief Summary
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The aim of this work is determine the more successful noninvasive method by comparison of two noninvasive methods ( IVC ultrasound - noninvasive hemoglobin measurement (SpHb)) that used in the detection of patients with blood loss. The works were completed in 6 months. The study was conducted at the blood donation center and in Emergency department. Vital parameters were measured and recorded before making the voluntary blood donation. Following Masimo brand portable device fingers SpHb value was measured.Then IVC diameter of patients in the supine position were measured using ultrasonography. Then he left to donors return in routine blood donation programme. A unit (500ml) of blood were drawn from each donor. After the blood donation process measured and recorded the vital signs again. SpHb was measured noninvasively from finger again. Following these measurements were recorded again by measuring the diameter of IVC.

Official Title
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Comparison of Noninvasive Two Methods to Monitoring Blood Loss; Inferior Vena Cava (IVC) Ultrasound - Non-invasive Hemoglobin Measurement (SpHb)

Conditions
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Blood Donors, Traumatic Blood Loss

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Who have volunteered to donate blood Older than 18 years Both sexes Exclusion Criteria: Known tricuspid valve regurgitation and right heart failure Oral intake or the fluid loss (diarrhea and vomiting-urination) between the two measurements during the blood donation Inappropriate echogenicity for vena cava inferior diameter measurement

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Prospective observational<br>The changes of IVC diameter, SpHb and vital signs of blood donors were observed after blood donation | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Diagnosis of stage 1 hemorrhagic shock | Changes in IVC diameter were observed with 500 ml blood loss. Measurement were made pre and post blood donation. | 30 minute (15 minute blood donation, 15 minute rest time ). | 
| Diagnosis of stage 1 hemorrhagic shock | Changes in SpHb were observed with 500 ml blood loss. Measurement were made pre and post blood donation. | 30 minute (15 minute blood donation, 15 minute rest time ). | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Diagnosis of stage 1 hemorrhagic shock | Changes in Pulse rate were observed with 500 ml blood loss. Measurement were made pre and post blood donation. | 30 minute (15 minute blood donation, 15 minute rest time ). | 
| Diagnosis of stage 1 hemorrhagic shock | Changes in Arterial blood pressure were observed with 500 ml blood loss. Measurement were made pre and post blood donation. | 30 minute (15 minute blood donation, 15 minute rest time ). | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Blood donors, blood donation, traumatic blood loss, Trauma