The Sex Specific Waist Circumference Cut Off Points to Predict Overweight or Obesity

Study Overview
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Brief Summary
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The waist circumference (WC) cut off levels of the Caucasian people may not represent the characteristics of different ethnic groups. The investigators aimed to determine sex specific WC cut off points to predict obesity, metabolic syndrome and increased cardiovascular risk in Turkish adults.

Detailed Description
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Waist circumference (WC) is an easy and reliable measure of visceral adipose tissue and a simple index of cardiovascular risk. The World Health Organization (WHO) reported sex specific WC cut off values for the Caucasian people, named as action levels 1 and 2, to define the overweight or obese people. These cut off values, originally established in a Dutch population, were later adopted by several medical organizations in order to define Metabolic Syndrome. However, these cut off levels may not necessarily represent the characteristics of the other populations. Therefore it is recommended that the sex specific WC cut off points should be established for different ethnic groups. The investigators aimed to investigate whether the suggested sex specific WC cut off points for the Caucasian adults are appropriate for the Turkish adult population. The secondary aim of the study is to search for better WC cut off points to predict obesity, metabolic syndrome and increased cardiovascular risk in Turkish adult men and women.

Official Title
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The Cross Sectional Study to Investigate the Waist Circumference Cut Off Points for the Prediction of Overweight and Obesity of the Turkish Adult Population

Conditions
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The Focus of Study is to Determine the Waist Circumference Values to Predict Overweight or Obesity

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adult Male or nonpregnant Female Exclusion Criteria: Pregnant females, Subjects younger than 20 or older than 83

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Healthy adults living in Turkey<br>The group was enrolled from the 24 provinces of the 7 regions of Turkey. At least 3 provinces were selected from each region by a random sampling method. The populations of these 7 regions were obtained from the records of the 2000 census. The study sample included males and non-pregnant females aged between 20 and 83 years. The populations of city centers, districts, and villages were classified by using the stratified sampling method and then were selected from the data collected from the household identification forms by random sampling. The geography of Turkey was classified into three groups according to altitude. Sea level was accepted as zero. 0-300 m was taken as coastal, 300-900 m as moderate | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Waist circumference cut off levels | These cut off levels were determined by the receiver operating curve analyses. The sum of the highest sensitivity and specificity values of the WC levels to determine the overweight (Body mass index (BMI) > 25kg/m2) and obese (BMI>30kg/m2) adults were taken as the cut off points. The cut off points to determine the overweight, were also taken as the WC limits for the diagnosis of metabolic syndrome. | About a year to collect all the demographic data | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Waist circumference, Metabolic Syndrome, Cardiovascular risk