Impact of Air Pollution and Climate Changes on the Epidemiology of Cardiovascular Disease

Study Overview
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Brief Summary
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Despite the fact that the topic of air pollution has been in focus of researchers for many years, there are no big studies that take up the matter of its influence on acute coronary, cerebral syndromes and CVD mortality in Europe. Taking into consideration the scarce number of surveys from Europe the investigators decided to analyze the impact of air pollution on cardiovascular diseases and CVD mortality in Poland.

Detailed Description
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Air quality and its impact on health was put in the spotlight since the infamous Great Smog of London. Since then, it became clear that adverse effects are serious and can no longer be ignored. According to the World Health Organization (WHO) estimations, in last year ambient air pollution caused 4,200,000 deaths worldwide. These statistics included a total of 29,165 deaths that were attributed to air pollution in Poland. The vast of studies are conducted in highly polluted areas, in which patients are exposed to extreme concentrations like China oraz Indie. Taking into consideration the scarce number of surveys from Europe the investigators decided to analyze the impact of air pollution and cardiovascular diseases in Poland. Data on morbidity and mortality were collected from the National Statistical Office in Poland. The data of air pollutions and gases were obtained from Voivodeship Inspectorate for Environmental Protection. The daily meteorological data were obtained from the Institute of Meteorology and Water Manageme

Official Title
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Impact of Air Pollution and Climate Changes on the Epidemiology of Cardiovascular Disease

Conditions
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Pollution; Exposure, Acute Coronary Syndrome, Chronic Coronary Insufficiency, Particulate Matter Inhalation Injury, Cardiovascular Diseases, Cardiovascular Risk Factor

Intervention / Treatment
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* Other: Impact of air pollution and climate changes


Participation Criteria
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Eligibility Criteria
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Inclusion criteria: - residents from analysed area. Exclusion criteria - none
Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Population of Poland<br>Exposure to short term long term effects of air pollution and climate change | Other: Impact of air pollution and climate changes<br>* To assess the short- and long- term impact of air pollution and climate changes<br>|
| Patients with Acute Coronary and Cerebral Syndromes<br>Exposure to short term long term effects of air pollution and climate change | Other: Impact of air pollution and climate changes<br>* To assess the short- and long- term impact of air pollution and climate changes<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of acute coronary syndromes | Number of acute coronary syndromes related with impact of air pollution | Through study completion, an average of 1 year | 
| Incidence of cardiovascular mortality | Number of cardiovascular deaths related with impact of air pollution | Through study completion, an average of 1 year | 
| Incidence of acute cerebral syndromes | Number of acute cerebral syndromes related with impact of air pollution | Through study completion, an average of 1 year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Air pollution, Particulate Matter, Acute Coronary Syndromes, Cardiovascular Disease, Risk factors