Different Intra-abdominal Pressures and Optic Nerve Size

Study Overview
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Brief Summary
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In intensive care patients, high intraabdominal pressure is frequently encountered. Intra-abdominal pressure is often measured as high, especially after major abdominal surgery procedures. In recent years, various studies have reported that the increase in optic nerve diameter measured by ultrasound correlates with the level of intracranial pressure. Optic nerve diameter measurement with ultrasound is a non-invasive procedure. Intra-abdominal pressure measurements are also routinely performed in intensive care patients. In the measurement of abdominal pressure, the bladder catheter, which is already available in every patient who comes to intensive care, is used. In this study, the intra-abdominal pressure values present in the file of each patient undergoing major abdominal surgery who were taken to intensive care unit will be taken. Orbital USG will be performed on the 6th, 12th and 24th hours on admission to the intensive care unit to measure the diameter of the optic nerve, and the relationship between the intra-abdominal pressure value and optic nerve diameters will be investigated.

Detailed Description
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In intensive care patients, high intraabdominal pressure is frequently encountered. Intra-abdominal pressure is often measured as high, especially after major abdominal surgery procedures. This situation creates ischemia in the abdominal organs in the patient, decreases venous return as a result of inferior vena cava compression and leads to a decrease in cardiac output. In addition, intracranial pressure frequently increases as a result of the venous circulation being affected. In recent years, various studies have reported that the increase in optic nerve diameter measured by ultrasound correlates with the level of intracranial pressure. Optic nerve diameter measurement with ultrasound is a non-invasive procedure. Intra-abdominal pressure measurements are also routinely performed in intensive care patients. In the measurement of abdominal pressure, the bladder catheter, which is already available in every patient who comes to intensive care, is used. In this study, the intra-abdominal pressure values present in the file of each patient undergoing major abdominal surgery who were taken to intensive care unit will be taken. Orbital USG will be performed on the 6th, 12th and 24th hours on admission to the intensive care unit to measure the diameter of the optic nerve, and the relationship between the intra-abdominal pressure value and optic nerve diameters will be investigated.

Official Title
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Investigation of the Effects of Different Intra-abdominal Pressures on Optic Nerve Size Measured by Orbital USG in Patients Undergoing Major Abdominal Surgery

Conditions
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Major Surgery, Intraabdominal Hypertension, Optic Nerve Congestion

Intervention / Treatment
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* Procedure: Intraabdominal pressure and optic nerve diameters


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Having had major abdominal surgery Exclusion Criteria: pregnant patients Patients whose bladder catheter cannot be inserted Patients with diagnosed or suspected brain death

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Intraabdominal pressure under 12 mmHg<br>Patients with intraabdominal pressure under 12 mmHg | Procedure: Intraabdominal pressure and optic nerve diameters<br>* Measuring Intraabdominal pressure with a Foley cathater and measuring optic nerve diameters with a USG<br>|
| Intraabdominal pressure between 12-20 mmHg<br>Patients with intraabdominal pressure between 12-20 mmHg | Procedure: Intraabdominal pressure and optic nerve diameters<br>* Measuring Intraabdominal pressure with a Foley cathater and measuring optic nerve diameters with a USG<br>|
| Intraabdominal pressure over 20 mmHg<br>Patients with intraabdominal pressure over 20 mmHg | Procedure: Intraabdominal pressure and optic nerve diameters<br>* Measuring Intraabdominal pressure with a Foley cathater and measuring optic nerve diameters with a USG<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| optic nerve diameter | measuring optic nerve diameter | within 2 hours of admission | 
| optic nerve diameter | measuring optic nerve diameter | at 6.hour | 
| optic nerve diameter | measuring optic nerve diameter | at 12.hour | 
| optic nerve diameter | measuring optic nerve diameter | at 24.hour |