Comparison of On-hours Versus Off-hours Anesthesia of Hip Surgery

Study Overview
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Brief Summary
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To explore the impact of the begin time of anesthesia on in-hospital mortality and early prognosis of patients undergoing hip surgery.

Detailed Description
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The patients undergoing hip surgery between were divided into the on-hours group or the off-hours group depending on the begin time of anesthesia in this retrospective cohort study. In-hospital mortality and early prognosis were compared between the two groups.

Official Title
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Comparison of Anesthesia Beginning at On-hours Versus Off-hours on Outcomes in Patients Undergoing Hip Surgery

Conditions
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Off-hours Anesthesia

Intervention / Treatment
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* Other: on-hours
* Other: off-hours


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All patients who had hip surgery between January 1, 2015, and December 31, 2020 in Tongji Hospital. Exclusion Criteria: under 18 years old had incomplete perioperative data

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| on-hours<br>Hip surgeries with the start time of anesthesia between 8:00 and 17:59 were coded as on-hours. | Other: on-hours<br>* If the begin time of anesthesia was between 8:00 to 17:59, it was defined as on-hours.<br>|
| off-hours<br>Hip surgeries with anesthesia beginning between 18:00 and 7:59 were coded as off-hours. Besides, taking the long duration of hip surgery into account, if the anesthesia began before 18:00 but ended after 20:00, it was also defined as off-hours. | Other: off-hours<br>* If the start time of anesthesia was between 18:00 to 7:59 or the end time of anesthesia was later than 20:00, it was defined as off-hours.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| in-hospital mortality | the mortality during hospitalization | up to 7 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| postoperative LOS | postoperative hospital length of stay | up to 4 months postoperatively | 
| total LOS | total hospital length of stay | up to 7 months | 
| ICU admission | the ratio of ICU admission | within 3 days postoperatively | 
| postoperative complications | including renal dysfunction, anemia, hypotension, deep vein thrombosis, arrhythmia, coronary artery disease or heart failure, pulmonary infection, electrolyte disturbance, hyoxemia and delirium | within 3 days postoperatively | 
| intraoperative fluid management | including blood loss, urine volume, concentrated red blood cells, fresh frozen plasma, equilibrium liquid and colloidal solution | intraoperative | 
| intraoperative sufentanil | the dosage of intraoperative sufentanil | intraoperative | 
| using vasoactive drugs | whether using vasoactive drugs or not intraoperatively | intraoperative | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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off-hours, hip surgery, perioperative care