Resistance Training in Patients With Parkinson's Disease.

Study Overview
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Brief Summary
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This is a controlled trial to assess the effects of resistance training on bradykinesia and physical function in patients with Parkinson's Disease. Forty patients diagnosed with Parkinson Disease stage 1 to 3 of the Hoehn and Yahr scale took part in the study and were allocated into 2 groups; Training Group performed a 9-week RT program twice a week while the Control Group attended lectures on the disease.

Official Title
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Effects of Resistance Training on Bradykinesia and Physical Function in Patients With Parkinson's Disease.

Conditions
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Parkinson Disease

Intervention / Treatment
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* Other: Resistance Training
* Other: Lectures on the disease


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Medical neurologist confirmation of 1-3 Hoehn and Yahr stages, age between 50 and 80 years old; and physician attested to participate in the resistance training program. Exclusion Criteria: Diagnostic of any other neurological disease, cardiovascular disease, hematologic or orthopedic disorders; and motor fluctuations or severe dyskinesia that could affect their ability to perform the experimental protocol.

Ages Eligible for Study
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Minimum Age: 50 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Training group<br>9-week resistance training program | Other: Resistance Training<br>* The TG performed the RT program using weight machines. Before the training period, participants underwent three weeks with eight familiarization sessions to ensure proper technique execution. The protocol aimed to workout major muscle groups and involved the following exercises: chest press, knee extension, hamstrings curl, leg press, and seated row. Training sessions lasted approximately 50-60 minutes with 2 sets of 10-12 repetitions until fatigue.<br>|
| Other: Control group<br>'Lectures on the disease' | Other: Lectures on the disease<br>* The control group attended an orientation program with lectures on health, quality of life and scientific update on disease.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bradykinesia measured with Unified Parkinson's Disease Rating Scale, section III |  | One time point; after the end of 9-week resistance training | 
| Functional Performance measured with Ten Meters Walk Test. |  | One time point; after the end of 9-week resistance training | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Muscle strength measured with isokinetic peak torque. |  | One time point; after the end of 9-week resistance training |