Wireless Assessment of Respiratory and Circulatory Distress in Chronic Obstructive Pulmonary Disease

Study Overview
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Brief Summary
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For patients admitted to the medical ward, it is usually difficult to predict if their clinical condition will deteriorate, however subtle changes in vital signs are usually present 8 to 24 hours before a life-threatening event such as respiratory failure leading to ICU admission, or unanticipated cardiac arrest. Such adverse trends in clinical observations can be missed, misinterpreted or not appreciated as urgent. New continuous and wearable 24/7 clinical vital parameter monitoring systems offer a unique possibility to identify clinical deterioration before patients progress beyond the point-of-no-return, where adverse events are inevitable. The WARD-COPD project aims to determine the number and duration of cardiopulmonary micro events during the first 4 days after hospital admission with Acute Exacerbation of COPD. We will also test the server installation, develop a database of core data and assess the frequency of artefacts and failure to capture the continuous monitoring signal.

Official Title
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Wireless Assessment of Respiratory and Circulatory Distress in Chronic Obstructive Pulmonary Disease - A Pilot Study

Conditions
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Chronic Obstructive Pulmonary Disease, Dyspnea

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adult patients admitted to hospital for Acute Exacerbation of COPD (AECOPD). Investigators will review the electronic patient chart for a primary diagnosis of AECOPD. Exclusion Criteria: Patient expected not to cooperate. Patient allergic to plaster, plastic or silicone. Active therapy withdrawn

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 100 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Blood oxygen saturation resulting in a single parameter score of 3 according to EWS algorithm | Hypoxemia: arterial oxygen saturation < 92 % | The patients are monitored for 4 days | 
| Heart rate resulting in a single parameter score of 3 according to EWS algorithm | All data from the monitoring will be analyzed using the thresholds from the EWS algorithm and will be sorted into relevant categories. The following thresholds are used: Bradycardia: pulse < 41 bpm Tachycardia: pulse > 130 bpm | The patients are monitored for 4 days | 
| Respiratory rate resulting in a single parameter score of 3 according to EWS algorithm | Bradypnea: < 9 breaths/min Tachypnea: > 24 breaths/min | The patients are monitored for 4 days | 
| Blood pressure resulting in a single parameter score of 3 according to EWS algorithm | Hypotension: Systolic blood pressure < 91 mmHg Hypertension: Systolic blood pressure > 219 mmHg | The patients are monitored for 4 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Wireless monitoring, Continuous monitoring, Vital parameters, Clinical deterioration