linjc16/ctgov huggingface dataset:
Preoperative Exercise Test and Postoperative Intensive Care Unit Need in Bariatric Surgery

Study Overview
=================
Brief Summary
-----------------
The aim of our study is to evaluate the efficacy of 60 meters 60 seconds exercise test (a test designed by the study group) done preoperatively as a predictor test for postoperative intensive care unit need and extubation success in patients undergoing bariatric surgery.

Official Title
-----------------
Use of Preoperative Exercise Test as Predictor for Postoperative Intensive Care Unit Need in Patients Undergoing Bariatric Surgery

Conditions
-----------------
Morbid Obesity, Weaning Failure

Intervention / Treatment
-----------------
* Diagnostic Test: preoperative walk test


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients between 18-60 years old patients with BMI > 40 patients undergoing Laparoscopic Sleeve Gastrectomy Exclusion Criteria: patients with Chronic obstructive pulmonary disease (COPD) or Asthma, patients with uncompensated heart failure Patients Who have orthopedic problems that effects the exercise test (such as gonarthrosis)

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 60 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Preoperative walk test<br>Patients undergoing bariatric surgery who will complete a preoperative 60 meters 60 seconds walk test. | Diagnostic Test: preoperative walk test<br>* Patients undergoing bariatric surgery who will complete a preoperative 60 meters 60 seconds walk test.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| extubation | Number of participants with successful extubation and patients who does not need mechanical ventilation support | one hour postoperative | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
bariatric surgery, extubation
Splinting Versus Not Splinting of the Distal Lower Extremity After Intramedullary Nailing for Tibial Fractures

Study Overview
=================
Brief Summary
-----------------
Two standards of care exist with regards to posterior splinting post-operatively. The proponents of splinting feel the additional immobilization decreases the stress on the soft tissue, subsequently preventing or limiting pain while improving early range of motion (ROM). The opposing belief is that the splinting is without therapeutic benefit and that early mobilization is beneficial. With regards to both practices, the surgeon's practice is anecdotally based on past experience. The purpose of this study is to compare the results obtained with and without posterior splinting after intramedullary (IM) nailing for tibia fractures in order to provide evidence based reasoning to guide future practice.

Official Title
-----------------
A Randomized Trial of Post-Operative Outcomes: Splinting Versus Not Splinting of the Distal Lower Extremity After Intramedullary Nailing for Tibial Fractures

Conditions
-----------------
Tibia Fracture

Intervention / Treatment
-----------------
* Procedure: Post-Op Splinting
* Procedure: No Splinting


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Isolated tibia fracture that is open grade II or less and all closed tibia fractures that are amenable to treatment with an IM nail Exclusion Criteria: Pregnant Women Prisoners

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 1. Splinting<br> | Procedure: Post-Op Splinting<br>* Splint will applied post-operatively and will remain on for two weeks<br>|
| Active Comparator: 2. No Splinting<br> | Procedure: No Splinting<br>* Patient will be discharged post-operatively without a splint on their lower leg.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Differences across time and between groups for pain and range of motion |  | 3 months |
Evaluation of the Management of Acute Appendicitis Before Emergency Department in Children: a Prospective Study

Study Overview
=================
Brief Summary
-----------------
Acute appendicitis is the first visceral surgical emergency in pediatrics with about 30,000 cases in children having been described in France. It concerns 0.3% of children under 15 with a maximum frequency between 8 and 13 years of age. Acute appendicitis has a significant morbidity rate of 8% and a mortality rate under 0.1%. 10 to 25% of the children admitted to emergency rooms for abdominal pain have appendicitis. In 20 to 30% of the cases, the initial symptoms are atypical, which explains the difficulty in diagnosing. The purpose of our study is to evaluate the quality of general practitioners in the diagnosis of acute appendicitis, its severity and the diagnostic criteria used. Furthermore, it is not as easy to evaluate pain or examine a complaint in children as it is in adults. Appendicectomy is the treatment of choice for all acute appendicitis. The importance of early diagnosis and treatment is, therefore, essential. Many predictive diagnostic scores have been studied over the years. The Pediatric Appendicitis Score (PAS) using typical symptoms of acute appendicitis and biological items was published in 2002. Nowadays, it is still considered as a reference and has been validated by other studies. Most of the patients suffering from abdominal pain first consult their general practitioner.

Official Title
-----------------
Evaluation of the Management of Acute Appendicitis Before Emergency Department in Children: a Prospective Study

Conditions
-----------------
Appendicitis

Intervention / Treatment
-----------------
* Other: PAS (Pediatric Appendicitis Score) survey


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Child <16 years abdominal symptoms consulting in the pediatric emergency department of Limoges University center. Exclusion Criteria: Child >=16 years

Ages Eligible for Study
-----------------
Minimum Age: 0 Years
Maximum Age: 16 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: PAS (Pediatric Appendicitis Score) survey|Score ≤ 5: appendicitis unlikely. Score ≥ 6: probable appendicitis. core ≥ 7: very probable appendicitis|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| PAS score | Score ≤ 5: appendicitis unlikely. Score ≥ 6: probable appendicitis. Score ≥ 7: very probable appendicitis | At 5 month | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Surgery for appendicitis |  | At 5 month |
INTERNATIONAL SURVEY ON COMPLEXITY IN LIVER TRANSPLANTATION

Study Overview
=================
Brief Summary
-----------------
The aim of this study is to perform an online survey to assess the perception of international liver transplant surgeons regarding the complexity and surgical difficulty in liver transplantation and to develop a complexity score and classification.

Official Title
-----------------
ASSESSMENT OF COMPLEXITY AND TECHNICAL DIFFICULTIES IN LIVER TRANSPLANTATION: INTERNATIONAL SURVEY OF EXPERTS

Conditions
-----------------
Liver Transplantation

Intervention / Treatment
-----------------
* Other: online survey


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: surgeons in liver transplantation center all countries Exclusion Criteria: none

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: online survey|An online survey including 8 case-vignettes was sent to international liver transplant surgeons who had published on liver transplantation. The first part is related to surgeon's own experience. In the second part, the surgeons were asked to rate the difficulty of various situations in liver transplantation on a scale of 1 to 10 (level 1 was labeled as easier, and level 10 was labeled as difficult). In the third part, 8 case-vignettes corresponding to 8 clinical real-life situations are submitted to experts|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Identify preoperative criteria to evaluate the degree of technical difficulty during a liver transplantation. |  | five minuts | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
complexity, international survey, surgical difficulty
Safety and Efficacy Study of Pirfenidone to Treat Grade 2 or Above Radiation-induced Lung Injury

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to assess the safety and efficacy of pirfenidone capsules to treat grade 2 or above radiation-induced lung injury patients.

Conditions
-----------------
Radiation Pneumonitis

Intervention / Treatment
-----------------
* Drug: Pirfenidone


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 18-70 years old (include 18 and 70 years), male or female The pathological diagnosis of lung cancer, with non-small cell lung cancer (NSCLC) staging IIIA or IIIB, and small cell lung cancer (SCLC) in council deadline General condition assessment, ECOG score of 0-1 Enough heart, liver and kidney function, such as AST, ALT, LDH≤2 times ULN such as plasma total bilirubin, creatinine ≤1.5 times ULN; hematopoietic function enough, such as neutrophils ≥4.0 x109 / L, platelets ≥100 x109 / L The expected survival at 6 months or more Subject is able to eat solid food The initial radical thoracic radiotherapy treatment The clinical diagnosis of radiation-induced lung injury in Grade 2 or above The duration of radiation-induced lung injury in less than 1 month Signed informed consent Exclusion Criteria: Radiation-induced lung injury has entered the chronic phase A history of chronic bronchitis, emphysema, or a history of cor pulmonale Lung resection surgery Cancer progression Pulmonary infection Associated with other serious diseases: such as occurred within 6 months of myocardial infarction, uncontrolled diabetes etc. With active peptic ulcer Pregnant women and patients with mental disease Those who participate in clinical trials of other drugs within 3 months Investigator judge does not apply to participate in the trial

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: treatment group<br> | Drug: Pirfenidone<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes in radiation-induced lung injury classification |  | 36 Weeks |
Percutaneous Electroneurostimulation of Dermatome T6 for Appetite Reduction and Weight Loss in Morbidly Obese Patients

Study Overview
=================
Brief Summary
-----------------
Based on the creation of a somato-autonomic reflex, the stimulation of sensory nerve terminals located in dermatome T6 may cause a reflex, whose efferent pathways end in vagal nerve branches stimulating the gastric wall, similarly to the gastric pacemaker. The aim of this study was to evaluate the effect of percutaneous electroneurostimulation (PENS) of T6 dermatome on appetite, weight loss and dietary compliance.

Official Title
-----------------
Percutaneous Electroneurostimulation of Dermatome T6 for Appetite Reduction and Weight Loss in Morbidly Obese Patients

Conditions
-----------------
Appetite Reduction, Weight Loss

Intervention / Treatment
-----------------
* Procedure: Percutaneous electroneurostimulation of dermatome T6
* Behavioral: Diet 1200 Kcal


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients candidates to bariatric surgery BMI > 40 Kg/m2 or a BMI > 35 Kg/m2 with comorbidities associated to the obesity status Failure of dietary treatment. Exclusion Criteria: untreated endocrine disease causing obesity serious psychiatric illness.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Diet<br>Diet 1200 Kcal during 3 months | Behavioral: Diet 1200 Kcal<br>* The patients assigned to this group must follow a 1200 Kcal diet during months<br>|
| Experimental: PENS associated to diet<br>Percutaneous electroneurostimulation of dermatome T6 associated to diet 1200 Kcal | Procedure: Percutaneous electroneurostimulation of dermatome T6<br>* The patients underwent a percutaneous electroneurostimulation of dermatome T6 during 30 minutes, every week during 12 weeks. This intervention was associated to a diet 1200 Kcal<br>Behavioral: Diet 1200 Kcal<br>* The patients assigned to this group must follow a 1200 Kcal diet during months<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Appetite reduction | The appetite reduction will be measured asking the patient to quantify the appetite sensation according to a visula analogic scale, ranged from 0 (absence of appetite) to 10 (incontrolable appetite). Appetite will be measured before the beginning of the treatment and after finishing it (after 12 weeks of treatment). | 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Weight loss |  | 3 months |
Study of Cardiac PET/CT Imaging to Guide Ablation Treatment of Ventricular Tachycardia

Study Overview
=================
Brief Summary
-----------------
Imaging is to be performed prior to procedure using positron emission tomography/ computed tomography (PET/CT), after a special dye is injected. The scans are going to be merged with other cardiac scans when doing the ablation procedure to correlate anatomy with physiology.

Official Title
-----------------
Cardiac Positron Emission Tomography for Detection of Cardiac Sympathetic Dysinnervation to Guide Ablation of Ventricular Tachycardia

Conditions
-----------------
Ventricular Tachycardia

Intervention / Treatment
-----------------
* Drug: [C-11] Meta-hydroxyephedrine radioactive tracer (MHED)


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Clinical indication for ventricular tachycardia (VT) ablation (at least one clinical episode of sustained VT) despite antiarrhythmic drug therapy, or if the patient does not wish to be on one Ischemic or nonischemic cardiomyopathy Sustained monomorphic VT Exclusion Criteria: Right ventricular VT Polymorphic VT or ventricular fibrillation (VF) being the sole detected clinical arrhythmia Patient is unable to sign informed consent Recent myocardial infarction less than 30 days Recent ablation for ventricular tachycardia less than 30 days Patient is unwilling or unable to cooperate with the study Prosthetic mitral or aortic valve General contraindications to VT ablation, e.g., major contraindication to anticoagulation therapy, known presence of left ventricular thrombus, reversible causes of VT or VF General contraindications to PET imaging, e.g., pregnancy or lactation General contraindication to magnetic resonance imaging or to the administration of gadolinium. Contraindication to the placement of hemodynamic support devices, i.e. the presence of mechanical valves or lack of adequate vascular access

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: [C-11] Meta-hydroxyephedrine radioactive tracer (MHED)|this tracer detects the distribution of sympathetic nerve fibers in the left ventricle|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| correlation between PET data and electroanatomic data |  | 1 week |
Physical Therapy Management in Degenerative Lumbar Diseases and Osteoporosis

Study Overview
=================
Brief Summary
-----------------
Low back pain is a common health issue in elderly population. According to the statistics, more than 80% of Taiwanese suffer low back pain in the life. The cause of low back pain includes lumbar spondylosis, osteoporosis, compression fracture, muscle strain, spondylolisthesis…etc. In addition to drugs and surgery, physical therapy is an alternative choice for conservative treatment. Therefore, in this study, the investigators propose to analyze the physical examination, diagnostic methods, X ray, physical therapy records, physical therapy methods and clinical outcomes in patients with the diagnosis including lumbar spondylosis, low back pain, osteoporosis, compression fracture, back pain treated at National Taiwan University Hospital and received rehabilitation at the Physical Therapy Center in recent ten years.

Official Title
-----------------
Physical Therapy Management in Degenerative Lumbar Diseases and Osteoporosis

Conditions
-----------------
Low Back Pain

Participation Criteria
=================
Eligibility Criteria
-----------------
Experimental group: Inclusion Criteria: patients with the diagnosis including lumbar spondylosis, low back pain, osteoporosis, compression fracture, back pain treated at National Taiwan University Hospital received rehabilitation at the Physical Therapy Center in recent ten years. Control group: Inclusion Criteria: patients with the diagnosis including lumbar spondylosis, low back pain, osteoporosis, compression fracture, back pain treated at National Taiwan University Hospital not received rehabilitation at the Physical Therapy Center in recent ten years.

Ages Eligible for Study
-----------------
Minimum Age: 50 Years
Maximum Age: 85 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
physical therapy, treated at NTUH and received rehabilitation at the PTC in recent ten years.
Clinical Evaluation of the CM-1500 in Postoperative Surgery Patients

Study Overview
=================
Brief Summary
-----------------
The primary objective is to evaluate the the changes in the Relative Index in post abdominal or pelvic surgery patients on the Cardiac Monitor Model CM-1500.

Detailed Description
-----------------
Postoperative hemorrhage incidence can vary depending on the type of surgery, but it can lead to severe clinical complications ranging from mild anemia to fatal hemorrhagic shock. Monitoring and detecting these fluid changes postoperatively can be complicated, and standard operating procedures vary. The Cardiac Monitor, Model 1500 (CM-1500), uses a personalized approach by non-invasively and simultaneously monitoring five (5) physiological parameters.

Official Title
-----------------
Clinical Evaluation of the CM-1500 in Postoperative Abdominal and Pelvic Surgery Patients

Conditions
-----------------
Blood Loss

Intervention / Treatment
-----------------
* Device: CM-1500


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Ability to provide written informed consent Ability and willingness to comply with study procedures and duration requirements 18 years of age or older Undergoing an abdominal or pelvic surgery within the next 10 days Exclusion Criteria: Females who are pregnant or breastfeeding Participation in other clinical studies involving experimental drugs or devices Undergone an amputation of the left upper extremity Diagnosed with Dextrocardia Subjects who have a Pacemaker

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 100 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Interventional Model Description: The study is a prospective, single-arm, non-randomized, non-controlled, single-center study enrolling adult subjects.
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Blood Volume Monitoring<br> | Device: CM-1500<br>* Blood volume monitor CM-1500<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Relative Index Change | The primary objective is to evaluate the the changes in the Relative Index in post abdominal or pelvic surgery patients | Acute |