AS-OCT Evaluation of Iridocorneal Angle of Patients of Angle Closure Glaucoma After Phacoemulsification

Study Overview
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Brief Summary
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Evaluation of the effect of phacoemulsification and YAG Laser peripheral iridotomy on the anterior chamber angle anatomic parameters in PACG eyes, using anterior segment optical coherence tomography (SS ASOCT) device

Detailed Description
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The recent treatment of ACG is phacoemulsification in patients of acute attack with YAG laser iridotomy in the other eye. The AS-OCT will be used for evaluation of the angle of the anterior chamber parameters in both eyes after phacoemulsification and YAG laser peripheral iridotomy. Follow up of AS-OCT will be done 1,3,6 months after surgery and we will compare results in each eye and between both eyes. .

Official Title
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Anterior Segment Optical Coherence Tomography Evaluation of Iridocorneal Angle of Patients of Angle Closure Glaucoma After Phacoemulsification and YAG Laser Iridotomy, Comparative Study

Conditions
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Glaucoma, Angle-Closure

Intervention / Treatment
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* Device: AS-OCT
* Procedure: YAG laser PI


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients with acute attack of angle closure glaucoma in one eye. Patients fit for phacoemulsification Exclusion Criteria: 1- Patients with history of any intraocular surgery. 2- Patients with history of refractive surgery. 3- Patients with diabetic retinal vasculopathy or retinal detachment. 4- Patients with chronic angle closure glaucoma, open angle glaucoma or 2ry glaucoma

Ages Eligible for Study
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Minimum Age: 30 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Angle opening distance (AOD)<br>The AOD measured as perpendicular distance between anterior iris surface and point at trabecular meshwork at 500 μm anterior to the scleral spur | Device: AS-OCT<br>* Anterior segment optical coherence tomography (AS OCT) is an imaging device that can acquire an anterior segment image using a noncontact method with the patient in a sitting position. This device provides reproducible and quantitative measurements of the AC angle and other anterior segment parameters.<br>Procedure: YAG laser PI<br>* medical procedure which uses a laser device to create a hole in the iris, thereby allowing aqueous humor to traverse directly from the posterior to the anterior chamber and, consequently, relieve a pupillary block<br>|
| Trabecular iris space area (TISA) 500<br>TISA 500 was measured as an area bounded anteriorly by the AOD 500, posteriorly by a line drawn from the scleral spur perpendicular to the plane of the inner scleral wall to the opposing iris, superiorly by the inner corneoscleral wall, and inferiorly by the iris surface | Device: AS-OCT<br>* Anterior segment optical coherence tomography (AS OCT) is an imaging device that can acquire an anterior segment image using a noncontact method with the patient in a sitting position. This device provides reproducible and quantitative measurements of the AC angle and other anterior segment parameters.<br>Procedure: YAG laser PI<br>* medical procedure which uses a laser device to create a hole in the iris, thereby allowing aqueous humor to traverse directly from the posterior to the anterior chamber and, consequently, relieve a pupillary block<br>|
| Anterior chamber depth (ACD)<br>The ACD was measured as the perpendicular distance from the corneal endothelium at the corneal apex to the anterior lens surface | Device: AS-OCT<br>* Anterior segment optical coherence tomography (AS OCT) is an imaging device that can acquire an anterior segment image using a noncontact method with the patient in a sitting position. This device provides reproducible and quantitative measurements of the AC angle and other anterior segment parameters.<br>Procedure: YAG laser PI<br>* medical procedure which uses a laser device to create a hole in the iris, thereby allowing aqueous humor to traverse directly from the posterior to the anterior chamber and, consequently, relieve a pupillary block<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| IOP | mmhg | up to 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Corneal endothelial count | CD per mm2 | up to 6 months |