COMPLI-PICC: Study on Picclines' Complications

Study Overview
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Brief Summary
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This is a prospective monocentric study of PICC Line complications use in 5 medical and one surgical units of Brest Medical University Hospital. To evaluate the incidence of the following complications: infections, thromboses, mechanical and hemorrhagic, at month 3 post-intervention. Also evaluating: the management of these PICC Line related complications, risk factors for such complications, and the mortality-related outcomes.

Detailed Description
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All eligible patients fulfilling the inclusion criteria, after PICC Line placement, will receive oral and written patient information describing the study deployment and follow-up. Patients will be followed up until PICC Line removal if it occurs during the first 3 months after placement or until death if it occurs during the first 3 months, or during 3 months in the absence of complications. Infectious complications are described in accordance with IDSA 2009 guidelines and include bloodstream infection, endocarditis, local infection and septic thrombophlebitis. Thrombotic complications are defined as symptomatic, deep, or superficial venous thrombosis, confirmed by Ultrasound and Echo-Doppler or asymptomatic venous thrombosis diagnosed fortuitously. Mechanical complications are defined as impairments related to PICC Line device: occlusion, rupture, accidental removal. Hemorrhagic complications are defined as hematoma or bleedings of puncture site. In the event of PICC Line-related complications, patient will be followed up for an additional 3 months, from the date of complication diagnosis, i.e. maximum follow-up duration of 6 months. Each week during the first month, then once monthly during the follow-up (i.e. W1, W2, W3, W4, M2, M3, +/- M4, M5, M6), all patients data related to the PICC Line retention or removal, use and all its related complications will be collected.

Official Title
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Prospective Observational Study on Picclines' Complications at Brest Hospital

Conditions
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PICC Line Placement

Intervention / Treatment
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* Procedure: Piccline


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patient > 18 yo Patients > 18 yo hospitalized in internal medicine, pneumology, nutrition, oncology, hematology, and cardiac and vascular surgery - who underwent PICC Line placement between October 10, 2016 and March 9, 2017 Exclusion Criteria: Patients hospitalized in other units than those cited above Patients verbal refusal to participate in the study

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients with PICC Lines<br>All patients included in this study have undergone PICC Line placement before enrollment. | Procedure: Piccline<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Complication in patient with piccline |  | 3 month | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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PICC Line, Complications, Thrombosis, Infection