Evaluation of an Apple Juice Drink With POs-Ca

Study Overview
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Brief Summary
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The null hypothesis tested was that there are no differences in the taste palatability of the apple juices before and after adding POs-Ca.

Official Title
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Development and Evaluation of a Low Erosive Apple Juice Drink With Phosphoryl Oligosaccharides of Calcium (POs-Ca)

Conditions
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Food Preferences

Intervention / Treatment
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* Dietary Supplement: apple juice
* Dietary Supplement: apple juice with 0.5% POs-Ca
* Dietary Supplement: apple juice with 1% POs-Ca
* Dietary Supplement: apple juice with 1.5% POs-Ca
* Dietary Supplement: apple juice with 2% POs-Ca


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: healthy adult subjects No eating or drinking within 30 minutes before the start time of the trials No tooth brushing within 30 minutes before the start time of the trials Exclusion Criteria: apple hypersensibility

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 25 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Placebo Comparator: 0% POs-Ca<br> | Dietary Supplement: apple juice<br>* unaltered(0% POs-Ca) commercially available apple juice<br>|
| Active Comparator: 0.5% POs-Ca<br> | Dietary Supplement: apple juice with 0.5% POs-Ca<br>* Phosphoryl Oligosaccharides of Calcium (POs-Ca) in the form of powder was added at concentrations of 0.5% by weight to a commercially available apple juice<br>|
| Active Comparator: 1% POs-Ca<br> | Dietary Supplement: apple juice with 1% POs-Ca<br>* Phosphoryl Oligosaccharides of Calcium (POs-Ca) in the form of powder was added at concentrations of 1% by weight to a commercially available apple juice<br>|
| Active Comparator: 1.5% POs-Ca<br> | Dietary Supplement: apple juice with 1.5% POs-Ca<br>* Phosphoryl Oligosaccharides of Calcium (POs-Ca) in the form of powder was added at concentrations of 1.5% by weight to a commercially available apple juice<br>|
| Active Comparator: 2% POs-Ca<br> | Dietary Supplement: apple juice with 2% POs-Ca<br>* Phosphoryl Oligosaccharides of Calcium (POs-Ca) in the form of powder was added at concentrations of 2% by weight to a commercially available apple juice<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual Analogue Scale of taste palatability | Tasters were first asked to drink the unaltered (0% POs-Ca) juice, to get familiar with the taste. After that they drank each of the 5 juices in a random order, and evaluated the taste by marking an analogue scale ranging from 0 to 100 which was printed horizontally on a sheet of paper. | At time when the subjects have finished drinking, an expected average of 10 minutes | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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POs-Ca, calcium additives, drink