Sore Throat Prevention Following Intubation

Study Overview
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Brief Summary
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The aim of this interventional study is to find out the incidence of sore throat among intubated patients in Jordan university hospital and to find out which is preventive and effective method to decrease sore throat;is it xylocaine gel on endotracheal cuff as lubricant versus dexamethasone 8 mg intravenously or both.

Detailed Description
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Three groups were divided into: first group received xylocaine gel as endotracheal cuff lubricant,second group received dexamethasone 8 mg intravenously and third group received both( xylocaine and dexamethasone). The investigator compared between the three groups regarding sore throat in intubated patients and followed them up to 48 hours.

Official Title
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Comparison Between Xylocaine Gel as Endotracheal Cuff Lubricant Versus Dexamethasone 8 mg Intravenously or Both for Sore Throat Prevention Following Intubation: Interventional Study

Conditions
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Sore Throat

Intervention / Treatment
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* Drug: xylocaine
* Drug: Dexamethasone
* Drug: Xylocaine and Dexamethasone


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: ASA 1-3. Elective VS Emergency. Cuffed endo-tracheal tubes. Different types of surgery. Exclusion Criteria: Pregnant ladies. ICU patients. <15 years of age Laryngeal mask airway

Ages Eligible for Study
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Minimum Age: 15 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Xylocaine X<br>Patients received xylocaine gel as lubricant on endotracheal tube | Drug: xylocaine<br>* First group were given xylocaine<br>* Other names: X;|
| Experimental: Dexamethasone D<br>Patients were given dexamethasone 8 mg intravenously | Drug: Dexamethasone<br>* Second group were given Dexamethasone<br>* Other names: D;|
| Experimental: xylocaine and dexamethasone XD<br>Patients were given both xylocaine gel and dexamethasone 8 mg intravenously | Drug: Xylocaine and Dexamethasone<br>* Third group were given both Xylocaine and Dexamethasone<br>* Other names: XD;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Comparison in preventing sore throat: xylocaine gel versus dexamethasone or both following intubation. | Questionnaire follow up in intubated patients. | 4 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Sore throat SCALE | Sore throat scale from None,mild,moderate till severe. | 4 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Sore Throat, Intubation, Xylocaine, Dexamethasone