Digital Interventions to Treat Hazardous Drinking

Study Overview
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Brief Summary
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There has been a significant increase in the prevalence of stress- and alcohol- related disorders during the COVID-19 pandemic. This project aims to study the impact of stress including COVID-19 related stress on increasing risk of alcohol misuse and treatment outcome in risky social drinkers after digital interventions.

Detailed Description
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This project aims to study the influence of stress on increasing risk of alcohol misuse and treatment outcome after digital interventions. This project proposes a digital intervention study using a prospective clinical outcome design with risky social drinkers (total N=30) with high and low stress. We will utilize a digital intervention method that combines telehealth- and smartphone app- based interventions, allowing concurrent treatment and daily monitoring in a real-life setting. All participants will receive a 4-week telehealth intervention (two sessions per week) using an intervention that integrates alcohol treatment with a breathing-based stress reduction method. Then, they will be prospectively followed for 30 days to monitor stress, alcohol use, social functioning, and other health-related behaviors.

Official Title
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Digital Interventions to Treat Hazardous Drinking

Conditions
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Hazardous Drinking, Stress

Intervention / Treatment
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* Behavioral: 4-week intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Heavy or binge drinkers Either high or low COVID-19 related stress Exclusion Criteria: Current or past substance use disorder other than mild alcohol, tobacco, marijuana use disorder Psychiatric disorders except for mood and anxiety disorders Any significant current medical conditions

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 55 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Intervention Model: Single Group Assignment
Interventional Model Description: All participants will receive a 4-week telehealth intervention involving alcohol treatment and breathing-based stress management. The effects of digital intervention will be assessed before and after the digital intervention.
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Risky drinkers<br>All participants will receive the same 4 week intervention. | Behavioral: 4-week intervention<br>* All participants will receive a digital intervention to reduce drinking for 4 weeks. There will be two therapy sessions each week using alcohol treatment combined with breathing-based stress management.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in alcohol use (quantity) | The average amount of alcohol use before and after intervention | baseline, after intervention (up to 30 days) | 
| Change in alcohol use (frequency) | Percent drinking days before and after intervention | baseline, after intervention (up to 30 days) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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COVID-19, Hazardous drinking, Stress, Digital intervention