Breathing Control Exercises in Patients With Chronic Obstructive Pulmonary Disease.

Study Overview
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Brief Summary
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The purpose of this study is to test whether breathing control exercises embedded in occupational therapy sessions have an impact on quality of life and dyspnea in patients with chronic obstructive pulmonary disease (COPD).

Detailed Description
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Dyspnea is one of the most important and debilitating symptoms in patients with COPD and is often the starting point to the vicious cycle of physical inactivity. As a consequence of increased dyspnea, patients adapt themselves by reducing the amount of all activities of daily living performed, with a consequent reduction in quality of life. Occupational therapists are involved in pulmonary rehabilitation programs aiming to improve the biopsychosocial condition of COPD patients. However, the specific roles and intervention of occupational therapists are not well-defined, and standardized protocols are lacking. The implementation of breathing control exercises in occupational therapy sessions, aiming among other things to regulate patient's breathing during their activities of daily living, could be a starting point for a more effective management of patients with COPD. This could ultimately participate in the improvement of quality of life in patients with COPD.

Official Title
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Impact of Occupational Therapy With Breathing Control Exercises in Patients With Chronic Obstructive Pulmonary Disease.

Conditions
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Severe Chronic Obstructive Pulmonary Disease

Intervention / Treatment
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* Behavioral: Standard Occupational Therapy
* Behavioral: Occupational Therapy with Breathing Control Exercises


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Confirmed diagnostic of COPD Severity of COPD: global initiative for chronic obstructive lung disease (GOLD) classification III or IV Undergoing a pulmonary rehabilitation program in J. Bracops Hospital Exclusion Criteria: Cardiac or orthopedic complications limiting participation in occupational therapy sessions Active smoking Inability to understand the French language orally or in writing Cognitive impairments limiting understanding of instructions and participation in occupational therapy sessions

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Standard Occupational Therapy<br>This group will receive standard occupational therapy sessions | Behavioral: Standard Occupational Therapy<br>* Standard occupational therapy sessions include patient therapeutic education (implementation of strategies and/or technical aids promoting autonomy and independence), walking and stair exercises in real-life conditions (weighted shopping bag, unstable ground, ...), as well as work on activities of daily living aiming to improve toileting skills (includes individual assessment, the use of technical aids depending of this assessment, and personalised strategies to conserve energy).<br>|
| Experimental: Occupational Therapy with Breathing Control Exercises<br>This group will receive the same component of the control group + breathing control exercises | Behavioral: Occupational Therapy with Breathing Control Exercises<br>* Includes the same treatment than the one described in standard occupation therapy but with the addition of 30-minute sessions per day on breathing control exercises. These exercises included the reproduction of gestures reproducing daily activities and simultaneous explanations of breathing techniques that the patient can perform in order to set up strategies for saving breath during exercise.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in St George's Respiratory Questionnaire score | Overall health, daily life, and perceived well-being are assessed via the St George's Respiratory Questionnaire and its three domains: symptoms, activities and impact. The score for each domain and the total score ranged from 0 to 100, with 100 indicating a very poor quality of life. | At baseline and after 6 weeks of pulmonary rehabilitation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in health-related quality of life | Health-related quality of life is assessed via the CAT (COPD assessment test) score. The assessment consists of eight questions, with a score associated with each question ranging from 0 to 5, with 0 indicating no impact on quality of life. The total score ranges from 0 to 40. The higher the score, the greater the impact on quality of life. | At baseline and after 6 weeks of pulmonary rehabilitation | 
| Change in dyspnea | Dyspnea is rated with a visual analogic scale (0 to 100mm). | At rest and after the effort, at baseline as well as after 6 weeks of pulmonary rehabilitation | 
| Change in hand grip strength | Hand grip strength test is assessed via a hand dynamometer (JAMAR). The best value of three repetitions of the best hand is reported. | At baseline and after 6 weeks of pulmonary rehabilitation | 
| Change in functional capacity | Functional capacity is assessed with the five-time sit-to-stand test. The time the individual takes to sit down and stand up completely over five repetitions is reported | At baseline and after 6 weeks of pulmonary rehabilitation | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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COPD, Chronic Obstructive Pulmonary Disease, Occupational therapy, Breathing control