Safety Related Factors of Endotracheal Intubation in Patients With Severe Covid-19 Pneumonia

Study Overview
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Brief Summary
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To analyze the intubation with severe covid-19 pneumonia, the infection rate of anesthesiologist after intubation, and summarizes the experience of how to avoid the infection of anesthesiologist and ensure the safety of patients with severe covid-19 pneumonia.

Detailed Description
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To analyze the intubation time, intubation condition, intubation process, intubation times and success rate of patients with severe covid-19 pneumonia, the infection rate of anesthesiologist after intubation, the degree of respiratory improvement and survival rate of patients, and summarizes the experience of how to avoid the infection of anesthesiologist and ensure the safety of patients with severe covid-19 pneumonia.

Official Title
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Analysis of Safety Related Factors of Endotracheal Intubation in Patients With Severe Covid-19 Pneumonia

Conditions
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COVID-19, Endotracheal Intubation

Intervention / Treatment
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* Other: severe covid-19 pneumonia with ET


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Wuhan residents; novel coronavirus pneumonia was found to be characterized by fever and cough. Laboratory tests revealed leukocyte or lymphocyte decrease, chest CT examination showed viral pneumonia changes, and was diagnosed as COVID-19 pneumonia according to the national health and Health Committee's new coronavirus pneumonia diagnosis and treatment plan (trial version fifth Revision). Severe and critical patients with covid-19 pneumonia in urgent need of tracheal intubation; Sign informed consent. Exclusion Criteria: Suspected patients with covid-19 pneumonia; Patients who need emergency endotracheal intubation due to other causes of respiratory failure; The family refused to sign the informed consent.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 90 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: severe covid-19 pneumonia with ET|severe covid-19 pneumonia undergoing endotracheal intubation|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Success rate of intubation | The data of Success rate of intubation with severe COVID-19 pneumonia patients | the time span between 1hour before intubation and 24h after intubation | 
| Infection rate of Anesthesiologist | Infection rate of Anesthesiologist who performed the endotracheal intubation for severe COVID-19 pneumonia patients | the time span between 1hour before intubation and 14days after intubation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Extubation time | Extubation time of intubated severe COVID-19 pneumonia patients | the time span between 1hour before intubation and 30days after intubation |