linjc16/ctgov huggingface dataset:
Immunological Changes Through Narrative Treatment of Post-Traumatic Stress Disorder (PTSD) in Torture Victims

Study Overview
=================
Brief Summary
-----------------
Posttraumatic stress disorder (PTSD) is associated with poor health, high health care utilization, and an increased risk for a variety of somatic, inflammatory and autoimmune diseases. Research, including our own findings, indicates immunological alterations in PTSD patients. The aim of this study is to investigate whether alterations in the immune system of PTSD patients are reversible through a trauma-specific short-term therapy (Narrative Exposure Therapy).

Official Title
-----------------
Immunological Changes Through Narrative Treatment of PTSD in Torture Victims

Conditions
-----------------
PTSD

Intervention / Treatment
-----------------
* Behavioral: NET


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: PTSD diagnosis experiences of organized violence/torture Exclusion Criteria: psychotic disorder chronic inflammatory diseases

Ages Eligible for Study
-----------------
Minimum Age: 16 Years
Maximum Age: 60 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Narrative Exposure Therapy (NET)<br> | Behavioral: NET<br>* Narrative Exposure Therapy for traumatized survivors of organized violence<br>|
| No Intervention: Waitinglist Control Group<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| PTSD diagnosis and severity score according to the Clinicians Administered PTSD Scale (CAPS) |  | 4 month after completion of treatment | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| changes in immunological parameters |  | 4 months after completion of treatment | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
PTSD, Narrative Exposure Therapy, torture victims, immune system
Midwifery Students' Performance Before and After Teaching Fundamentals of Documentation

Study Overview
=================
Brief Summary
-----------------
Midwives are responsible for documenting and keeping care facts in midwifery departments. Inaccurate documentation or even minute error in reporting may lead to burdensome responsibility for midwives. This study has been conducted aimed to compare midwifery students' performance before and after teaching fundamentals of documentation. In this quasi-experimental study, 28 midwifery students were participated. Data were collected by a questionnaire including a. demographic data and b. Scenarios (1) and (2) of an imaginary patient with physician order and a checklist contain 11 elements of documentation

Conditions
-----------------
Documentation Skill

Intervention / Treatment
-----------------
* Other: lecture


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: midwifery students studying at mashhad school of nursing and midwifery Exclusion Criteria: any other discipline

Ages Eligible for Study
-----------------
Minimum Age: 21 Years
Maximum Age: 22 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: midwifery students<br>all midwifery students studying at last term (except one who was absent) (27) in Mashhad school of nursing and midwifery in April 2011 | Other: lecture<br>* Teaching documentation skill using lecture method<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| compare midwifery students' performance before and after teaching fundamentals of documentation using lecture method |  | up to one month | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Students practice, Lecture; Nursing records; Nursing education; Midwifery
Rehabilitation in Chronic Obstructive Pulmonary Disease (COPD) Patients With Emphysema

Study Overview
=================
Brief Summary
-----------------
Chronic Obstructive Pulmonary Disease has two heterogeneous conditions (chronic bronchitis and pulmonary emphysema phenotypes) with a different clinical presentation. The phenotype evaluation in COPD patient (trough clinical, functional and radiographic parameters) could influence final results in pharmacologic and non-pharmacologic management of the disease. The aim of our study is to investigate whether COPD patients with different disease phenotype (chronic bronchitis versus pulmonary emphysema) have a different response to PR.

Official Title
-----------------
Effectiveness of Pulmonary Rehabilitation in Chronic Obstructive Pulmonary Disease (COPD) Patients With Emphysema Phenotype

Conditions
-----------------
Chronic Obstructive Pulmonary Disease, Emphysema

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: COPD disease with any functional grade Adherence to participate to a pulmonary rehabilitation program Exclusion Criteria: Recent acute exacerbation (4 weeks preceding enrollment) Acute severe concomitant cardiovascular diseases Concomitant neoplastic diseases NO-Adherence to participate to a pulmonary rehabilitation program

Ages Eligible for Study
-----------------
Minimum Age: 40 Years
Maximum Age: 90 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Emphysema phenotype<br> | |
| No-Emphysema phenotype<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Exercise tolerance | Change in Six minute walked distance (6MWD) | [Time Frame: Day 1 and 20 ] | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Dyspnoea | Change in dyspnea grade by MRC | [ Time Frame: Day 1 and 20] | 
| Symptoms on effort | Change in Dyspnoea and leg fatigue by Borg scale | [ Time Frame: Day 1 and 20] | 
| Perceived Quality of life | Change in Saint George Respiratory Questionnarie (Italian version) | [ Time Frame: Day 1 and 20] | 
| Global function | Change in the multidimensional BODE index (validated in COPD population) | [ Time Frame: Day 1 and 20] | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
COPD, Emphysema phenotype
Effect of Breast Implants om Mammography Screening

Study Overview
=================
Brief Summary
-----------------
The purpose of the study is to survey how many women have breast implants in the mammography screening population and the effect of implants on the number and type of examinations and on costs.

Official Title
-----------------
Effect of Breast Implants om Mammography Screening

Conditions
-----------------
Breast Cancer

Intervention / Treatment
-----------------
* Diagnostic Test: Mammography screening


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Women participating in the mammography screening program. Exclusion Criteria: None

Ages Eligible for Study
-----------------
Minimum Age: 40 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
Female

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Women without breast implants<br>Women without breast implants participating in the mammography screening program. | Diagnostic Test: Mammography screening<br>* Breast screening mammograms use X-rays to look for cancers that are too small to see or feel.<br>* Other names: Breast cancer screening;|
| Women with breast implants<br>Women with breast implants participating in the mammography screening program. | Diagnostic Test: Mammography screening<br>* Breast screening mammograms use X-rays to look for cancers that are too small to see or feel.<br>* Other names: Breast cancer screening;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Costs | Health economic analysis of the effects of implants on mammography screening | 1 year post-operatively | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prevalence | Prevalence of breast implants in a mammography screening population. | 1 year | 
| Frequency of need for additional examinations | Survey of if breast implants infer extra examinations (mammography, ultrasounds, biopsies, diagnostic operations) in connection with screening mammography. | 1 year | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
breast cancer, plastic surgery, breast implant, mammography screening, health economy
Intraoperative Monitoring to Predict Postoperative Complications After Thyroidectomy

Study Overview
=================
Brief Summary
-----------------
The goal of this study is to evaluate the role of intraoperative continous and intermittent neuromonitoring and intraoperative parathormone (PTH) to predict postoperative nerve morbidity and hypocalcemia.

Detailed Description
-----------------
Intraoperative PTH values and intraoperative continuous neuromonitoring will be collected prospectively in consecutive patients who undergo total thyroidectomy. Postoperative parathyroid morbidity and recurrent laryngeal nerve morbidity will be evaluated within 1 week after total thyroidectomy and at 1 year postoperatively. Other postoperative morbidity will be evaluated at 1 year postoperatively using validated classification.

Official Title
-----------------
Intraoperative Monitoring (Parathormone Values and Continuous Neuromonitoring) to Predict Postoperative Complications After Total Thyroidectomy

Conditions
-----------------
Endocrine Procedural Complications, Thyroid, Parathyroid; Deficiency, Laryngeal Injury

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients scheduled for total thyroidectomy in university of Nancy (University Hospital) Exclusion Criteria: refusal to participate
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| intraoperative parathormone values | parathormone in pg/mL | intraoperative | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| postoperative hypocalcemia | calcium in mg/L | within 1 week after thyroidectomy | 
| postoperative hypoparathyroidism | parathormone in pg/mL | within 1 week after thyroidectomy | 
| permanent postoperative hypocalcemia | calcium in mg/L | at one year after thyroidectomy | 
| permanent postoperative hypoparathyroidism | parathormone in pg/mL | at one year after thyroidectomy | 
| laryngeal nerve palsy | continuous intraoperative neuromonitoring (> 50% baseline values yes/no) | during thyroidectomy | 
| laryngeal nerve palsy | laryngoscopy (normal / palsy) | within 1 week after thyroidectomy | 
| laryngeal nerve palsy | laryngoscopy (normal / palsy) | at one year after thyroidectomy | 
| Postoperative complications other than outcomes from 1 to 8 | Postoperative morbidity classification (using a Clavien-Dindo classification) postoperatively | at one year after thyroidectomy |
GooDMoMS: A Multimodel Pregnancy and Postpartum Intervention for Gestational Diabetics

Study Overview
=================
Brief Summary
-----------------
This study includes a behavioral educational intervention that focuses on healthy eating and physical activity during pregnancy and the postpartum among women newly diagnosed with gestational diabetes mellitus (GDM).

Detailed Description
-----------------
This is a pilot trial in which 30 women newly diagnosed with gestational diabetes are randomized to either one of two groups: 1) active internet intervention or 2) self-directed educational intervention. The primary pregnancy outcome is change in A1C. The primary postpartum outcome is weight.

Official Title
-----------------
GooDMomS: A Multimodel Pregnancy and Postpartum Intervention for Gestational Diabetics

Conditions
-----------------
Gestational Diabetes Mellitus, Pregnancy

Intervention / Treatment
-----------------
* Behavioral: lifestyle counseling


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Diagnosed with gestational diabetes Planning to delivery with the study area Exclusion Criteria: Pre-existing diabetes (type 1 or type 2 diabetes) Non-English speaking Not planning to delivery in the study area

Ages Eligible for Study
-----------------
Minimum Age: 21 Years
Maximum Age: 35 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Lifestyle counseling<br>Participants obtain access to an internet-based educational intervention. | Behavioral: lifestyle counseling<br>* Participants receive lifestyle counseling on healthy eating and physical activity through an internet-based program or self-directed educational program.<br>* Other names: glucose control;|
| Other: Usual Care Lifestyle counseling<br>Self directed educational intervention | Behavioral: lifestyle counseling<br>* Participants receive lifestyle counseling on healthy eating and physical activity through an internet-based program or self-directed educational program.<br>* Other names: glucose control;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in glycosylated hemoglobin |  | Baseline and 36 weeks gestation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in weight after pregnancy |  | 6 weeks postpartum to 24 weeks postpartum | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
gestational diabetes
From Acute to Chronic Postoperative Pain in Patients for Elective Cholecystectomy. Immunological Tests

Study Overview
=================
Brief Summary
-----------------
Chronic Pain after Cholecystectomy is a well known problem. One theory is that it is due to persisting inflammation. The purpose of the study is to measure inflammatory factors in cerebrospinal fluid and blod at patients 12 months after the operation. DNA-samples are collected to examine genetical factors, important for perception of pain, and the development of chronic pain.

Official Title
-----------------
From Acute to Chronic Postoperative Pain in Patients for Elective Cholecystectomy. Immunological Tests

Conditions
-----------------
Pain

Participation Criteria
=================
Eligibility Criteria
-----------------
Group 1: Inclusion Criteria: Unexplained abdominal pain 12 months after elective cholecystectomy Exclusion Criteria: Immunosuppressive treatment (NSAID excepted) Anticoagulant treatment Group 2: Inclusion Criteria: No pain 12 months after elective cholecystectomy Exclusion Criteria: Immunosuppressive treatment (NSAID excepted) Anticoagulant treatment Group 3: Inclusion Criteria: Elective operation in spinal anesthesia or Or healthy volunteers accepting samples of blod, cerebral spinal fluid and saliva, to be collected Exclusion Criteria: Acute or chronic pain condition Immunosuppressive treatment (NSAID excepted) Previous abdominal operation

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Pain patients<br>Patients with unexplained chronic abdominal pain 12 months after elective cholecystectomy | |
| Operated painfree Patients<br>Painfree patients 12 months after elective cholecystectomy | |
| Nonoperated painfree patients<br>Painfree patients with no previous abdominal operation | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Spinal interleukine levels | 12 months after surgery | 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Blood interleukine levels |  | 12 Months | 
| spinal enzyme levels | 12 months after surgery | 12 months | 
| Blood enzyme levels | 12 months after surgery | 12 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Chronic postoperative pain, Postcholecystectomy pain, Inflammation, Interleukines
Turkish Thoracic Society Usual Interstitial Pneumonia Registry Study

Study Overview
=================
Brief Summary
-----------------
The Turkish Thoracic Society Usual Interstitial Pneumonia Registry (TURK-UIP) is a collaborative project to coordinate a team of investigators from various regions of Turkey. The purpose of the Registry is to collect epidemiological data on patients with idiopathic pulmonary fibrosis and other causes of UIP, and to obtain information about the natural course of the disease and the treatment response.

Detailed Description
-----------------
The TURK-UIP Registry is a web based application that will store information about patients. A HRCT pattern consistent with UIP will be confirmed by 3 radiologists. At the 3-month visits, the pulmonary function tests and the 6-minute walk test will be recorded. Patients will be prospectively followed for a 5-year period.

Official Title
-----------------
Turkish Thoracic Society Usual Interstitial Pneumonia Registry Study

Conditions
-----------------
Idiopathic Pulmonary Fibrosis, Usual Interstitial Pneumonia

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Understand and sign the informed consent document. The presence of a definite or possible UIP pattern on high resolution computed tomography (HRCT) or a histologic UIP pattern (definite, probable and possible) on surgical lung biopsy (as defined by ATS/ERS/JRS/ALAT criteria). Exclusion Criteria: HRCT findings inconsistent with UIP pattern (peribronchovascular predominance, extensive ground glass abnormality,profuse micronodules, discrete cysts , consolidation in bronchopulmonary segment(s)/lobe(s), diffuse mosaic attenuation/air-trapping), Histopathological findings inconsistent with UIP pattern (as defined by ATS/ERS/JRS/ALAT criteria).

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of subjects enrolled with IPF and other causes of UIP | Natural history of course of disease in patients with IPF and other causes of UIP. | 5 years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Idiopathic Pulmonary Fibrosis, Usual Interstitial Pneumonia
Study Evaluating the Safety of Enbrel (Etanercept)

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to collect post-marketing information on the safety of Enbrel in Filipino patients.

Official Title
-----------------
A Prospective, Observational Study to Monitor Safety in Patients Who Were Administered With Etanercept (Enbrel) 25 mg by Subcutaneous Injection

Conditions
-----------------
Arthritis, Psoriatic

Intervention / Treatment
-----------------
* Drug: Etanercept (Enbrel)


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: All patients from the study center who received or will receive at least one dose of Enbrel according to the approved product indication. Exclusion Criteria: Previously discontinued Enbrel therapy due to significant safety concern.
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| 1<br> | Drug: Etanercept (Enbrel)<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of Participants With Spontaneous Adverse Events Reported Until 30 Days After Each Injection |  | 30 days post injection up to 3 years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Arthritis, psoriatic