The Effect of Air Pollution on Lung Health Among School Children Living in Haifa Bay Region

Study Overview
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Brief Summary
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Haifa bay region is located close to a major industrial zone. The aim of the study is to evaluate the health status of school children living in Haifa bay region.The health status will be evaluated using health questionnaires and spirometry.

Detailed Description
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Haifa bay is located close to a major industrial zone. The aim of the study is to evaluate the health status of children living in Haifa bay region. The health status will be evaluated while using health questionnaires and spirometry. Objective: To evaluate the respiratory health of Haifa bay region children with comparatives, with respect to local air pollution levels. Material and Methods: Children from Haifa bay region from 10 different communities (1200 children) will be included in the study, after both parents and the children (above 12 years of age) will sign an informed consent form. First step: A health questionnaire (based on Hebrew version of ISAAC questionnaire) will be filled in by the parents. Second step: Spirometry checking of the children. In parallel, air pollution levels will be measured and provided by a network of ground monitoring stations maintained by the Haifa District Municipality Association for the Environment (HDMAE). The station provides half-hourly measurement of mean concentrations of gaseous (NOX, SO2, O3) and particular (PM 10) pollutants over the entire investigation window. Additional meteorological data are also collected. Risk maps: Using a GIS platform, we are developing a multi-layer risk mapping procedure which accounts for ambient concentrations of selected pollutants and the heterogenic spatial distribution of several demographic and socio-economic indexes in the region. The prevalence of pulmonary disease will be evaluated according to the risk maps The health status of the children will be documented from the children's primary clinic files as well.

Official Title
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The Effect of Air Pollution on Lung Health Among School Children Living in Haifa Bay Region

Conditions
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Bronchial Asthma, Signs and Symptoms, Respiratory, Allergy

Intervention / Treatment
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* Device: Spirometry (Pony spirometer)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Living in Haifa bay region, Israel. Parents signed informed consent. Exclusion Criteria: Children that their parents did not signed the informed consent Chronic disease except of asthma: Diabetes mellitus, Cystic Fibrosis, Cardiac diseases, Renal, Rheumatic and Chronic Gastrointestinal diseases, Mental retardation.

Ages Eligible for Study
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Minimum Age: 6 Years
Maximum Age: 12 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: 1<br>School children from Haifa bay region, Israel. | Device: Spirometry (Pony spirometer)<br>* Spirometry at rest<br>* Other names: Pony spirometer, Cosmed, Italy;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The prevalence of respiratory symptoms in respect to air pollution |  | Two years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Asthma, Allergy, Respiratory, Pollution, Children, Air pollution