Ionized Magnesium Balance During Hemodialysis Session

Study Overview
=================
Brief Summary
-----------------
Aim of this study is to evaluate in a population of chronic kidney disease patients on dialysis (Stage 5D) the balance of total and ionized magnesium according to different types of dialysate used in clinical practice (acetate + Mg 0.50 or 0.75 mM vs citrate + Mg 0.50 ou 0.75 mM)

Official Title
-----------------
Ionized Magnesium Balance During Hemodialysis Session

Conditions
-----------------
Chronic Kidney Diseases

Intervention / Treatment
-----------------
* Biological: Lymphatic drainage
* Biological: Total and ionized magnesium
* Biological: Total and ionized calcium


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion criteria: Chronic Kidney Disease patient on dialysis (stage 5D) for more than 1 month Anuric patient Exclusion criteria: Patient protected by law Patient under guardianship ou curatorship Patient deprived of liberty

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| All patients receive conventional dialysis treatment at enrollment<br>All patients receive conventional dialysis treatment at enrollment | Biological: Lymphatic drainage<br>* Biological determination in plasma:<br>* Other names: Biological determination in plasma:;Biological: Total and ionized magnesium<br>* Total and ionized magnesium<br>Biological: Total and ionized calcium<br>* Total and ionized calcium<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Comparison of ionized magnesium levels before and after dialysis session | Comparison of ionized magnesium levels before and after dialysis session | day 1 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Comparison of total magnesium levels before and after dialysis session | Comparison of total magnesium levels before and after dialysis session | day 1 | 
| Comparison of ionized calcium levels before and after dialysis session | Comparison of ionized calcium levels before and after dialysis session | day 1 | 
| Comparison of total calcium levels before and after dialysis session | Comparison of total calcium levels before and after dialysis session | day 1 | 
| Per-dialytic balance of ionized magnesium according to predialysis level | Per-dialytic balance of ionized magnesium according to predialysis level | day 1 | 
| Per-dialytic balance of total magnesium according to predialysis level | Per-dialytic balance of total magnesium according to predialysis level | day 1 | 
| Per-dialytic balance of ionized calcium according to predialysis level | Per-dialytic balance of ionized calcium according to predialysis level | day 1 | 
| Per-dialytic balance of total calcium according to predialysis level | Per-dialytic balance of total calcium according to predialysis level | day 1 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Chronic Kidney Disease patient on dialysis (stage 5D), Extracorporeal purification, Ionized magnesium