Cervical Gland Area as a Predictor of Success of Labour Induction

Study Overview
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Brief Summary
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Women who fulfil the inclusion criteria and who are planned for labour induction will be recruited. Bishop score, cervical length, and the presence of cervical glandular area (CGA) will be documented for every patient up to 12 hours prior to the induction process, and patient information and maternal and neonatal outcome will be documented following the delivery.

Detailed Description
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Patient consent to participate in the study will be retrieved following the medical decision of labor induction and the mode of induction and following the patient consent to the induction. Bishop score, cervical length, and the presence of cervical glandular area (CGA) will be documented for every patient up to 12 hours prior to the induction process. The method of induction, data regarding patient demographics, the progress of labor, and the maternal and neonatal outcome will be documented following the delivery.

Official Title
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Cervical Gland Area as a Predictor of Success of Labour Induction

Conditions
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Induced Vaginal Delivery

Intervention / Treatment
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* Diagnostic Test: Ultrasound examination


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Singleton and twins' pregnancies Pregnancy 34-41 weeks of gestation Vertex presentation Induction methods (Oxytocin, prostaglandin 1 (PGE1), prostaglandin 2 (PGE2), double balloon catheter, rupture of memebrane (ROM) Exclusion Criteria: Intrauterine fetal demise (IUFD) Contraindication to vaginal delivery Status post cervical cerclage Previous attempt of labor induction History of cervical surgery Active vaginal bleeding

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: Ultrasound examination|Women that are planned for labour induction, will undergo a routine ultrasound examination prior to the initiation of the induction process.|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Onset of active labour | Percent of patients that reached the active stage of labour (defined as measurement of cervical dilation of greater than 6 cm) | Up to delivery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Time from Induction to second stage | Duration of time from initiation of labpur induction to cervical dilation of 10cm | Up to delivery | 
| Time from Induction to delivery | Duration of time from initiation of labpur induction to delivery | Up to delivery | 
| Rate of vaginal delivery | The rate of patient that deliver vaginally including instrumental deliverires | Up to delivery | 
| Neonatal outcome - PH | The fetal arterial pH measuerment following the delivery | Up to 10 minutes from delivery | 
| Neonatal outcome - APGAR (Apearance, Pulse, Grimace, Activity, Respiration score) | The fetal APGAR score as recieved by pediatrician | Up to 5 minutes from delivery | 
| Neonatal outcome - NICU (Neonatal Intensive Care Unit) admission | Percent of neonated that requiered NICU admission | Up to 48 hours from delivery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Labour induction, Cervical glandular area