Study of the Closed-loop Treatment Concept of Atrial Fibrillation in the Atrial Fibrillation Population

Study Overview
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Brief Summary
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This study aims to evaluate the concept of closed-loop treatment of atrial fibrillation for the optimization of the treatment strategy.

Detailed Description
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This study aims to evaluate the concept of closed-loop treatment of atrial fibrillation for the optimization of the treatment strategy, the improvement of disease outcome and the economic value of the atrial fibrillation population in the northern Shanghai community. Improve the disease cognition of patients with atrial fibrillation, and promote the development of the concept of closed-loop treatment of atrial fibrillation.

Official Title
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Application of the Closed-loop Treatment Concept of Atrial Fibrillation in the Atrial Fibrillation Population in the Northern Shanghai Community

Conditions
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Atrial Fibrillation

Intervention / Treatment
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* Procedure: Radiofrequency ablation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: atrial fibrillation patients；Ability to act autonomously, understand and sign informed consent； Exclusion Criteria: none（All patients with atrial fibrillation were enrolled in this study indiscriminately and followed up）

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 100 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Closed-loop Group<br>Groups of Patients Adhering to Closed-Loop Therapy. | Procedure: Radiofrequency ablation<br>* Combined use of radiofrequency ablation, cryoablation, left bundle branch pacing, and left atrial appendage closure according to the actual situation of the patient.<br>* Other names: left atrial appendage occlusion;;|
| No Closed-loop Group<br>Patients who have not undergone closed-loop treatment or patients who have not undergone standard surgery and medication. | |
| Exchange Group<br>Groups of patients with delayed compliance with closed-loop therapy for atrial fibrillation. | Procedure: Radiofrequency ablation<br>* Combined use of radiofrequency ablation, cryoablation, left bundle branch pacing, and left atrial appendage closure according to the actual situation of the patient.<br>* Other names: left atrial appendage occlusion;;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Atrial fibrillation recurrence | The recurrence of atrial fibrillation and the degree of burden of atrial fibrillation in patients. | 2 years | 
| Heart failure | Degree of heart failure (including EF%, NYHA score, etc.) | 5 years | 
| Stroke | stroke attack(Check for new cerebral infarction by MRI） | 5 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| bleeding | major bleeding event | 2 years | 
| Cardiovascular MACE events | Cardiovascular MACE events | 5 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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atrial fibrillation；closed-loop treatment；