Interval Training and Resting Metabolism

Study Overview
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Brief Summary
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It has been reported that obese individuals are seated 2 ½ hour more than lean individuals and that non exercise thermo genesis (NEAT) may vary with as much as 2000 Kcal/day between equal size people due to different occupational and leisure time activities. The primary aim of the study is to investigate if 10 weeks of exercise training increase NEAT in sedentary men. Subject will be randomized to three different training intervention, with 3 exercise session each week for 10 weeks. NEAT will be measured using an activity sensor and recorded over a 7 day period both before and after training.

Official Title
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Effect of Aerobic Interval Training on NEAT in Sedentary Men

Conditions
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Healthy Subjects

Intervention / Treatment
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* Behavioral: 1 x 4 minute interval
* Behavioral: 4 x 4 minutes Intervals
* Behavioral: Moderate continuous Training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Male gender Age 18-50 BMI 25-30 kg x m2 No significant comorbidities Abel to exercise Not partaking in organized physical activity Exclusion Criteria: Inability to exercise due to musculoskeletal conditions Known ischemic cardiovascular disease High daily physical and occupational activity levels

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 4 x 4 Interval<br>4 x 4 minutes of high intensity intervals at 90-95% of maximal heart rate separated by 3 minutes of active brakes in between at 70% of maximal heart rate. | Behavioral: 4 x 4 minutes Intervals<br>* 4 x 4 minutes of high intensity intervals at 90-95% of maximal heart rate separated by 3 minutes of active brakes in between at 70% of maximal heart rate.<br>|
| Experimental: 1 4 minutes interval<br>1 x 4 minutes intervals at 90-95% of HR max | Behavioral: 1 x 4 minute interval<br>* 1 x 4 minutes of high intensity intervals at 90-95% of maximal heart rate<br>|
| Experimental: Moderate continuous Training<br>47 minutes of Moderate continuous Training | Behavioral: Moderate continuous Training<br>* 47 minutes of Moderate continuous Training<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| nonexercise activity thermogenesis | NEAT Will be measured using an activity sensor. Physical activity is recorded over a 7 day period. The energy equivalent of each of these activities is determined. The time spent in each activity is then multiplied by equivalent for the activity. The values are then summed to derive an estimate of NEAT. | Baseline and 10 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cardiopulmonary maximal oxygen uptake | The secondary aims are to investigate the changes in maximal oxygen uptake, heart function, and body composition in response to interval training | Baseline and 10 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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NEAT, maximal oxygen uptake, stroke volume