Comparison of Spinal Kinematics Between Asymptomatic Subjects and Patients With Low Back Pain

Study Overview
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Brief Summary
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Low back pain (LBP) is a complex and common problem with major societal repercussions. Clinical evaluations, and especially functional assessments, are necessary for proper diagnosis and decisions on the most appropriate treatment. The assessment of lumbar kinematics has been frequently described. For instance, measures of range of motion (ROM), angular velocities and acceleration of the total lumbar spine (TLx) have demonstrated some differences between healthy subjects and LBP patients. However, recent evidence has suggested that models evaluating the TLx are insufficient. In fact, regional differences in kinematics have been described between the upper lumbar spine and the lower lumbar spine. The aim of this study is to evaluate the differences in spinal kinematics between healthy subjects and LBP patients using a multi-segment model of the spine that allows regional analysis.

Detailed Description
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A case-controlled study will be performed to compare asymptomatics subjects and patients with low back pain. ROM, angular velocities and coordination of the spine will be collected in a laboratory with a camera-based system (VICON). Subjects will have to perform normal ROM assessment in the three anatomical planes, as well as different functional activities such as sit to stand, step and walking. The measurement session will occur on one occasion for each participant.

Official Title
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Comparison of Spinal Kinematics Between Asymptomatic Subjects and Patients With Low Back Pain Using a Multi-segment Model

Conditions
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Low Back Pain

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Sufficient French level BMI between 18 and 27 Non-specific low back pain for more than 3 months (pain provoked by movements, postures or activities) Exclusion Criteria: Pregnancy Spondylolisthesis Infection Rheumatological or neurological diseases Spinal fractures Known spinal deformation (scoliosis, …) Back surgery Tumours Radicular symptoms (with neurological signs). Pain irradiating in the lower limbs with decrease strength, sensitivity and reflex. High level of pain (severity and irritability) at the time of experiment that prevents repeated movements. Other concomitant pain or condition that could compromise the evaluation of lumbar kinematics.

Ages Eligible for Study
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Minimum Age: 30 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Asymptomatic<br>Individuals between 30 and 50 years old that have had no episode of low back pain in the last two years requiring medical attention | |
| Patients with Low Back Pain<br>Individuals between 30 and 50 years old that present with non-specific low back pain for more than 3 months | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Spinal kinematics | kinematics of the spine and pelvis will be measured with a camera-based system. Markers will be placed to have different segments of the spine (lower lumbar spine, upper lumbar spine, lower thoracic spine, upper thoracic spine). Variables such as range of motion, angular velocities or coordination (among others) will be measured. | Participants will be measured once | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Score of disability | Oswestry Disability Index. Outcome used primarily for description of the population and correlational analysis | Participants will be measured once | 
| Score of kinesophobia | Tampa Scale of kinesophobia. Outcome used primarily for description of the population and correlational analysis | Participants will be measured once | 
| Score of risk of poor outcomes | Start Back Tool. Outcome used primarily for description of the population and correlational analysis | Participants will be measured once | 
| Pain intensity | Numeric Pain Rating Scale (NPRS). Outcome used primarily for description of the population and correlational analysis | Participants will be measured once | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Spinal kinematics