Comparison of Intubating Condition of the Mcgrath Videolaryngoscope With and Without Muscle Relaxant

Study Overview
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Brief Summary
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The objective of this study was to evaluate intubating condition using the McGrath® VL Series 5, with and without muscle relaxant

Detailed Description
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Thirty-four patients with ASA classification I-II, who required oroendotracheal tube intubation, were studied in this prospective, double-blinded, randomized, clinical trial. Anesthesia was induced using fentanyl 1.5 mcg/kg, xylocaine 1.5 mg/kg and propofol 3 mg/kg. Patients were randomly assigned to one of the two groups to receive either rocuronium 0.6 mg/kg or saline intravenously. The Mcgrath® VL intubation was initiated after 90s, when the patients were fully relaxed. The primary outcome was to compare tracheal intubating conditions between two groups. The secondary outcomes were the success rate in the first attempt intubation, time to intubation, the required propofol dose for intubation and anesthetic complications. Statistical analyses were performed using the R program version 2.14.2. The level of statistical significance was set at p < 0.05.

Official Title
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Comparison of Intubating Condition of the Mcgrath Videolaryngoscope With and Without Muscle Relaxant

Conditions
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Muscle Relaxant

Intervention / Treatment
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* Device: Videolaryngoscope


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 18-65 years old. ASA class I-II. Elective surgery required general anesthesia with oroendotracheal intubation Exclusion Criteria: Suspected or known difficult airway. Patient with risk of aspiration with required of rapid sequence induction . Plan remained intubation. Allergic to drugs used in the study. Renal or hepatic disease.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Muscle relaxant<br>Intubation with McGrath video laryngoscope after fentanyl 1.5 mcg/kg, xylocaine 1.5 mg/kg and propofol 3 mg/kg muscle relaxant use rocuronium 0.6 mg/kg | Device: Videolaryngoscope<br>* Intubation with McGrath video laryngoscope after muscle relaxant<br>|
| Placebo Comparator: Placebo<br>Intubation with McGrath video laryngoscope after fentanyl 1.5 mcg/kg, xylocaine 1.5 mg/kg and propofol 3 mg/kg placebo use NSS 0.6 mg/kg | Device: Videolaryngoscope<br>* Intubation with McGrath video laryngoscope after muscle relaxant<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Intubating condition. | number of participants with 34 people | one year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Success rate in the first attempt intubation. |  | one year | 
| Time to intubation |  | One year | 
| The required propofol dose for intubation without muscle relaxant. |  | one year | 
| Events during the intubation attempts occurred. |  | one year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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McGrath®, Videolaryngoscope, intubating condition, muscle relaxant, intubation