Creatine Supplementation in Female Collegiate Dancers

Study Overview
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Brief Summary
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This study will be a 6 week creatine supplementation intervention with performance familiarization and pre and post testing. Participants will report to the human performance laboratory (HPL) for baseline to read and sign an informed consent explaining the procedures and potential risks and benefits of participation. Participants will then complete a physical activity readiness questionnaire (PAR-Q) prior to performing any physical tasks. Participants will also be asked to complete testing below in the order described. Participants will become familiar with the pre/post performance tests, which include isokinetic testing, medicine ball throw, vertical jump, and Wingate testing. Twenty-four hours following visit 1, participants will return to the HPL for visit 2 where they will undergo a second familiarization session for the isokinetic testing and Wingate testing only - these two tests require individuals to provide maximal physical efforts and research suggests that participants should perform multiple familiarization trials before beginning experimental trials. At least 72 hours following visit 2, participants will return to the HPL for visit 3 to perform the baseline performance assessments. Following the baseline assessments, participants will be divided into two supplementation groups: creatine and placebo (maltodextrin). These groups will be randomized and matched based on body mass, hours of dance training per week, meat intake, and menstrual cycle phase. Participants will be asked to consume one of the two supplements daily for 42 consecutive days and maintain their regular dance training and eating behaviors. Participants will report to the HPL daily to receive their supplement between the hours of 12pm and 2pm. Following the last day of supplement consumption, participants will report to the HPL to perform post-testing assessments which will be identical to pre testing.

Official Title
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Effects of Creatine Supplementation on Performance, Body Composition and Mental Health in Female Collegiate Dancers

Conditions
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Creatine

Intervention / Treatment
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* Dietary Supplement: Creatine
* Dietary Supplement: Placebo


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Collegiate dance major or minor Exclusion Criteria: Injured within the past 6 months Currently consuming creatine supplements

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 24 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Creatine Supplementation<br> | Dietary Supplement: Creatine<br>* Participants will consume 0.1g/kg body weight of creatine with 0.1g/kg body weight of maltodextrin for 42 consecutive days<br>|
| Placebo Comparator: Placebo Supplementation<br> | Dietary Supplement: Placebo<br>* Participants will consume 0.2g/kg body weight of maltodextrin for 42 consecutive days<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in fat mass from baseline after 42 days | Dual energy x-ray absorptiometry used to assess fat mass (% and kg) | Change from baseline fat mass at 42 days | 
| Change in lean mass from baseline after 42 days | Dual energy x-ray absorptiometry used to assess lean mass (% and kg) | Change from baseline lean mass at 42 days | 
| Change in visceral adipose tissue from baseline after 42 days | Dual energy x-ray absorptiometry used to assess visceral adipose tissue (cm2) | Change from baseline visceral adipose tissue at 42 days | 
| Change in peak muscular strength from baseline after 42 days | Cybex isokinetic dynamometry used to assess peak muscular strength (W) | Change from baseline peak muscular strength at 42 days | 
| Change in peak vertical jump height from baseline after 42 days | Cybex isokinetic dynamometry used to assess vertical jump height (in) | Change from baseline peak vertical jump height at 42 days | 
| Change in upper body muscular power from baseline after 42 days | Seated medicine ball toss used to assess upper body muscular power (in) | Change from baseline upper body muscular power at 42 days | 
| Change in muscular power from baseline after 42 days | Wingate anaerobic power test used to assess muscular power (W) | Change from baseline muscular lower at 42 days | 
| Change in depression, anxiety and stress score from baseline after 42 days | Depression, anxiety and stress scale (from 0, normal to 42, extremely severe) used to assess depression, anxiety and stress | Change from baseline depression, anxiety and stress at 42 days | 
| Change in cognitive performance from baseline after 42 days | NIH Toolbox for the assessment of Neurological and Behavioral Function ipad application to assess fluid cognitive measures including executive function, attention, episodic memory, processing speed, and working memory. | Change from baseline cognitive performance at 42 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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creatine, body composition, dancer, cognition