Laparoscopic Segmental Bowel Resection for Deep Infiltrating Colorectal Endometriosis

Study Overview
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Brief Summary
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This study is executed to evaluate the outcome on quality of life, pain, sexuality, pregnancy rate and recurrence rate after a fertility sparing multidisciplinary CO2 laser laparoscopic radical excision of deep infiltrating colorectal endometriosis with a bowel resection.

Detailed Description
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Patients All women (n=45) who had undergone fertility sparing CO2 laser laparoscopic radical excision of deep infiltrating endometriosis with bowel resection were selected retrospectively from the list of all patients (n=more than 500, of whom slightly more than 50% with endometriosis) operated at the Leuven University Fertility Centre (LUFc) between September 2004 and September 2006. Questionnaires All 45 patients were asked to complete the Oxford Endometriosis Quality of Life questionnaire (27), a sexual activity questionnaire (28), visual analogue scales (VAS) for dysmenorroe, chronic pelvic pain and deep dyspareunia, and to answer questions about medication and fertility, to compare their status before surgery and at the moment of the evaluation (December 2008).

Official Title
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A Retrospective Follow-up of Patients After Laparoscopic Segmental Bowel Resection for Deep Infiltrating Colorectal Endometriosis

Conditions
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Endometriosis

Intervention / Treatment
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* Procedure: multidisciplinary laparoscopy
* Other: Questionnaires


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients suffering from deep infiltrating endometriosis with colorectal extension Who had undergone CO2 laser laparoscopic radical excision of the endometriosis with bowel resection performed by the colorectal surgeon between September 2004 and July 2006. Exclusion Criteria: Patients without bowel resection

Ages Eligible for Study
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Minimum Age: 19 Years
Maximum Age: 43 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| 1<br>All women (n=45) who had undergone CO2 laser laparoscopic radical excision of deep infiltrating endometriosis with active involvement of the colorectal surgeon performing a bowel resection were selected retrospectively from the list of all patients (n=more than 400) operated at the Leuven University Fertility Centre (LUFc) between September 2004 and July 2006. | Procedure: multidisciplinary laparoscopy<br>* Laparoscopic segmental bowel resection for deep infiltrating colorectal endometriosis performed by an experienced colorectal surgeon.<br>Other: Questionnaires<br>* All 45 patients were asked to complete the Oxford Endometriosis Quality of Life questionnaire, a sexual activity questionnaire, visual analogue scales (VAS) for dysmenorroe, chronic pelvic pain and deep dyspareunia, and to answer questions about medication and fertility, to compare their status before surgery and at the moment of the evaluation (December 2008).<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain; Sexuality; Quality of life; Fertility rate; Complication rate; Recurrence rate |  | a median follow-up of 27 months (range 16 - 40 months) after surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Economic life circumstances |  | a median follow-up of 27 months (range 16 - 40 months) after surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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colorectal endometriosis, deep infiltrating endometriosis, dysmenorroe, dyspareunia, quality of life