Reducing Disabilities in Alzheimer's Disease (RDAD) Translation in Area Agencies on Aging (AAAs)

Study Overview
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Brief Summary
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The University of Washington's Northwest Research Group on Aging is partnering with Area Agencies on Aging (AAA) in Washington and Oregon to complete this translational investigation of RDAD (Reducing Disabilities in Alzheimer's Disease). RDAD is an evidence-based program with demonstrated efficacy in helping older adults with dementia maintain physical function and remain physically and mentally healthy. This study asks two questions: 1) Can AAA partners successfully translate and implement RDAD, and 2) Is AAA implementation of RDAD effective in producing desired outcomes among agencies, providers, and older adults with dementia and their family members. This study is being conducted in Washington and Oregon states.

Official Title
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From Evidence-Base to Practice: Implementing RDAD in AAA Community-Based Services

Conditions
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Alzheimer's Disease, Dementia, Memory Impairment, Cognitive Impairment

Intervention / Treatment
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* Behavioral: RDAD


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Care Recipients must Have a diagnosis of dementia Be 65 years of age or older Currently exercise no more than 150 minutes a week and not regularly participate in a formal exercise program. Caregivers must Live in the community Provide care to the care recipient with dementia Exclusion Criteria: Either Care-recipient or Caregiver must not Plan to move to a long-term residential care setting within 6 months of enrollment. Plan to move from the study geographic area within 4 months of enrollment. Have a known terminal illness (with death anticipated within the next 12 months) Have had a hospitalization for a psychiatric disorder in the 12 months prior to baseline Be actively suicidal, hallucinating, or delusional Be blind, deaf, or not ambulatory

Ages Eligible for Study
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Minimum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: RDAD<br>Exercise training for caregiver and care recipient. Behavior modification training for caregiver. | Behavioral: RDAD<br>* Exercise training for caregiver and care recipient. Behavioral modification training for caregiver.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Minutes of exercise per week | Caregivers will track the number of minutes per week the care recipients engage in exercise recommended by the coach. | Change from baseline in number of minutes of exercise each week during treatment phase of study, weeks 7-12 | 
| Restricted Activity Days | Restricted Activity Days measures how much the participant cut down his/her usual activities in the previous two weeks because of injury or illness and how many days the participant stayed in bed in the previous two weeks because of injury or illness. | Baseline | 
| Restricted Activity Days | Restricted Activity Days measures how much the participant cut down his/her usual activities in the previous two weeks because of injury or illness and how many days the participant stayed in bed in the previous two weeks because of injury or illness. | Change from Baseline to Pre-Treatment (6 weeks) | 
| Restricted Activity Days | Restricted Activity Days measures how much the participant cut down his/her usual activities in the previous two weeks because of injury or illness and how many days the participant stayed in bed in the previous two weeks because of injury or illness. | Change from Baseline to Post- Treatment 1 (13 weeks) | 
| Restricted Activity Days | Restricted Activity Days measures how much the participant cut down his/her usual activities in the previous two weeks because of injury or illness and how many days the participant stayed in bed in the previous two weeks because of injury or illness. | Change from Baseline to Post-Treatment 2 (30 weeks) | 
| Restricted Days of Activity | Restricted Activity Days measures how much the participant cut down his/her usual activities in the previous two weeks because of injury or illness and how many days the participant stayed in bed in the previous two weeks because of injury or illness. | Change from Baseline to 13 Month Follow-Up | 
| Independence/Residential Status | All participants will be in independent living situations at baseline. Any move from independent living to a care facility will be documented throughout the 13 month study. | Change from Baseline to 13 Month Follow-Up | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Revised Memory and Behavior Problem Checklist (RMBPC) | Checklist rates 24 care recipient behaviors for frequency of occurrence and caregiver reaction. | Baseline | 
| Revised Memory and Behavior Problem Checklist (RMBPC) | Checklist rates 24 care recipient behaviors for frequency of occurrence and caregiver reaction. | Change from Baseline to Pre-Treatment (6 weeks) | 
| Revised Memory and Behavior Problem Checklist (RMBPC) | Checklist rates 24 care recipient behaviors for frequency of occurrence and caregiver reaction. | Change from Baseline to Post-Treatment 1 (13 weeks) | 
| Revised Memory and Behavior Problem Checklist (RMBPC) | Checklist rates 24 care recipient behaviors for frequency of occurrence and caregiver reaction. | Change from Baseline to Post-Treatment 2 (30 weeks) | 
| Revised Memory and Behavior Problem Checklist (RMBPC) | Checklist rates 24 care recipient behaviors for frequency of occurrence and caregiver reaction. | Change from Baseline to 13 Month Follow-Up | 
| Quality of Life-AD | This 13-item measure is specifically designed for individuals with dementia and focuses on quality of life domains identified as important for cognitively impaired older adults. | Baseline | 
| Quality of Life-AD | This 13-item measure is specifically designed for individuals with dementia and focuses on quality of life domains identified as important for cognitively impaired older adults. | Change from Baseline to Pre-Treatment (6 weeks) | 
| Quality of Life-AD | This 13-item measure is specifically designed for individuals with dementia and focuses on quality of life domains identified as important for cognitively impaired older adults. | Change from Baseline to Post-Treatment 1 (13 weeks) | 
| Quality of Life-AD | This 13-item measure is specifically designed for individuals with dementia and focuses on quality of life domains identified as important for cognitively impaired older adults. | Change from Baseline to Post-Treatment 2 (30 weeks) | 
| Quality of Life-AD | This 13-item measure is specifically designed for individuals with dementia and focuses on quality of life domains identified as important for cognitively impaired older adults. | Change from Baseline to 13 Month Follow-Up | 
| CES-D | This 20-item scale that assesses depression in caregivers. | Baseline | 
| CES-D | A 20-item scale that assesses depression in caregivers. | Change from Baseline to Pre-Treatment (6 weeks) | 
| CES-D | A 20-item scale that assesses depression in caregivers. | Change from Baseline to Post-Treatment 1 (13 weeks) | 
| CES-D | A 20-item scale that assesses depression in caregivers. | Change from Baseline to Post-Treatment 2 (30 weeks) | 
| CES-D | A 20-item scale that assesses depression in caregivers. | Change from Baseline to 13 Month Follow-Up | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Dementia, Alzheimer's Disease, Exercise, Caregiver, Behavior modification