External Oblique Intercostal Plane Block for Laparoscopic Sleeve Gastrectomy

Study Overview
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Brief Summary
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The external oblique intercostal (EOI) plane block is a novel approach upper abdominal wall analgesia. The EOI plane block can provide dermatomal sensory blockade of T6-T10 at the anterior axillary line and T6-T9 at the midline. It may be used for postoperative analgesia in obese patients because it is superficial and rapidly identifiable and performed in the supine position. the aim of this study is to investigate the postoperative analgesic efficacy of external oblique intercostal plane block in obese patients undergoing laparoscopic sleeve gastrectomy. Researchers will compare the external oblique intercostal plane block group with control group to see if the EOI plane block is effective for postoperative analgesia in patients undergoing sleeve gastrectomy.

Detailed Description
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Patients scheduled for elective laparoscopic sleeve gastrectomy will be separated into 2 groups: Control Group and External Oblique Intercostal Plane Block Group. Patients in Control Group will be received patient controlled analgesia with morphine for postoperative analgesia. Patients in External Oblique Intercostal Plane Block Group will be performed bilateral External Oblique Intercostal Plane Block before the surgery and received patient controlled analgesia with morphine for postoperative analgesia. Morphine consumption for first postoperative 24 hours, visual analog scale scores, time to need for first rescue analgesia, amount of rescue analgesic drug, incidence of postoperative nausea and vomiting will be recorded.

Official Title
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External Oblique Intercostal Plane Block for Postoperative Analgesia in Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy

Conditions
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Obesity, Analgesia, Postoperative Pain

Intervention / Treatment
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* Other: Intravenous morphine patient control device
* Other: External oblique intercostal plane block


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age between 18 and 80 years Patients with American Society of Anesthesiology (ASA) physical status II-III Patients scheduled for a laparoscopic sleeve gastrectomy Exclusion Criteria: Allergy to local anesthetics Coagulopathy Skin infection at the EOI Plane Block area Advanced hepatic or renal failure Chronic pain syndromes Alcohol or drug abuse Severe pulmonary and/or cardiovascular disease Psychiatric disorders

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Control group<br>The patients in Control Group will be received patient controlled analgesia with morphine for postoperative analgesia | Other: Intravenous morphine patient control device<br>* 24-hour morphine consumption will be recorded<br>|
| Active Comparator: External oblique intercostal plane block group<br>The patients in external oblique intercostal plane block group will be received EOI plane block and patient controlled analgesia with morphine for postoperative analgesia | Other: Intravenous morphine patient control device<br>* 24-hour morphine consumption will be recorded<br>Other: External oblique intercostal plane block<br>* External oblique intercostal plane block will be administered before the surgery.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Morphine consumption | The amount of morphine required by the patient and given by the device will be recorded for the first 24 hours. | Postoperative 24 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative visual analog scale scores | Postoperative pain will be assessed using a visual analog scale (VAS) (from 0 = no pain to 10 = maximum possible pain) for the first 24 hours. | Postoperative 24 hours | 
| Time to first rescue analgesic | The time for administration of first rescue analgesic will be recorded. | postoperative 24 hours | 
| Rescue analgesic drug consumption | The amount of rescue analgesic in mg required by the patient will be recorded for the first 24 hours. | postoperative 24 hours | 
| Incidence of postoperative nausea and vomiting | Number of patients developing postoperative nausea and vomiting will be recorded for the first 24 hours | postoperative 24 hours |