Women's Quality of Life, Sexual Life and Psychological State in Patients Undergoing Embryo Transfers

Study Overview
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Brief Summary
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Women's quality of life, sexual life and psychological state would affect the success of embryo transfer. The primary purpose of the study is to compare women's quality of life, sexual life and psychological state using validated forms between those undergoing fresh embryo transfer and those undergoing frozen embryo transfer.

Detailed Description
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There are two types of embryo transfers; fresh and frozen embryo transfers. Studies have been conducted to compare success rates between fresh and frozen embryo transfers. However, most studies have not taken into consideration women's quality of life, sexual life and psychological state in comparing fresh embryo transfer with frozen embryo transfers. These all parameters are confounding factors that may influence the success of embryo transfer. The purpose of this study is to compare women's quality of life, sexual life and psychological state using validated forms between those undergoing fresh embryo transfer and those undergoing frozen embryo transfer. The following forms will be used: expanded version of the inventory of depression and anxiety symptoms (IDAS-II), Beck Anxiety inventory (BAI), Short Form Survey (SF-36) and Female Sexual Function Index (FSFI. This study can provide evidence regarding the association between women's quality of life, sexual life and psychological state and embryo transfer success.

Official Title
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Do Women's Quality of Life, Sexual Life and Psychological State Differ Between Patients Undergoing Fresh and Frozen Embryo Transfers: a Prospective Study

Conditions
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Infertility, Female, Anxiety State, Depression, Quality of Life, Sexual Function and Fertility Disorders

Intervention / Treatment
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* Other: Filling out the forms including IDAS-II, BAI, SF-36 and FSFI


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age between 20 - 39 years Body mass index between 18 -3 5 kg/m2 Anti-mullerian hormone levele >1.1 ng/ml or antral follicle count > 8 fresh or frozen embryo transfer using middle-quality or good-quality day 3 or 5 embryos Exclusion Criteria: Age below 20 or over 39 years Uterine malformations Hypo or hyperthyroidism Diabetes mellitus Previous history of psychiatric disorders Use of psychiatric medications Systemic disorders (hypertension, chronic liver/kidney/heart problems)

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 39 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Fresh embryo transfers<br>those undergoing fresh embryo transfer | Other: Filling out the forms including IDAS-II, BAI, SF-36 and FSFI<br>* Participants will fill out certain validated forms including the expanded version of the inventory of depression and anxiety symptoms (IDAS-II), Beck Anxiety inventory (BAI), Short Form Survey (SF-36) and Female Sexual Function Index (FSFI).<br>|
| Frozen embryo transfers<br>those undergoing frozen embriyo transfer | Other: Filling out the forms including IDAS-II, BAI, SF-36 and FSFI<br>* Participants will fill out certain validated forms including the expanded version of the inventory of depression and anxiety symptoms (IDAS-II), Beck Anxiety inventory (BAI), Short Form Survey (SF-36) and Female Sexual Function Index (FSFI).<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Clinical pregnancy rate | Clinical pregnancy is defined as the presence of intrauterine fetal heartbeat at around 7 weeks of gestation. | At around 7 weeks of gestation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Implantation rate | Implantation is defined as presence of intrauterine gestational sac at around 6 weeks of gestation. | At around 6 weeks of gestation | 
| Live birth rate | Live birth is defined as at least a live birth after 24 completed weeks of gestation. | 24 completed weeks of gestation |