Measurements of Displacement Amplitude and Angular Velocities During Passive Extension of the Wrist and Hand Complex in Stroke Patients

Study Overview
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Brief Summary
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The main objective of this monocentric prospective study is to evaluate the amplitudes and angular velocities of extension of the hand and wrist joints during passive mobilization by a physiotherapist in healthy subjects and stroke patients with spastic hands. Secondary objectives: To compare amplitude and angular velocity values between the group of stroke patients and the group of healthy volunteers, To compare amplitude and angular velocity values according to the two types of mobilization (i,e, thumb or fifth finger), To assess pain due to mobilization in stroke patients.

Detailed Description
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Conduct of research: The realization of the measures will take place at the GHRMSA rehabilitation department. After receiving the written consent of the study participant, the physiotherapist will proceed with the passive mobilization of the spastic hand of the stroke patient or the dominant hand for healthy volunteers. Videos of the hand will be made using the Darfish system which will allow analysis of the primary endpoint. Two mobilizations will be performed for each participant, i.e. one for each type of medial or lateral grip. The order of mobilization will be determined by randomization.

Official Title
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Measurements of Displacement Amplitude and Angular Velocities During Passive Extension of the Wrist and Hand Complex in Stroke Patients

Conditions
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Muscle Spasticity, Stroke

Intervention / Treatment
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* Procedure: Passive extension mobilization of the hand and wrist joints


Participation Criteria
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Eligibility Criteria
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Eligibility criteria of stroke patients with hand spasticity: Inclusion Criteria: Age ≥ 18 years old First stroke diagnosed less than 3 months ago Non-functional wrist defined by the Fugl-Meyer Assesment (FMA-EU) upper limb motor subscale with a score ≤45 Wrist flexor spasticity defined by the Modified Tardieu Scale (MTS) with a rating ≥1 Written informed consent Exclusion Criteria: - None Eligibility criteria of healthy volunteers: Inclusion criteria: Age ≥ 18 years old Written informed consent Exclusion Criteria: - None

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Stroke patients with hand spasticity (n=20)<br> | Procedure: Passive extension mobilization of the hand and wrist joints<br>* The physiotherapist will proceed with the passive mobilization of the spastic hand of the stroke patient or the dominant hand for healthy volunteers. Two mobilizations will be performed for each participant, i.e. one for each type of medial or lateral grip. The order of mobilization will be determined by randomization.<br>|
| Other: Healthy volunteers (n=10)<br> | Procedure: Passive extension mobilization of the hand and wrist joints<br>* The physiotherapist will proceed with the passive mobilization of the spastic hand of the stroke patient or the dominant hand for healthy volunteers. Two mobilizations will be performed for each participant, i.e. one for each type of medial or lateral grip. The order of mobilization will be determined by randomization.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Amplitude values | Amplitude values will be calculated with the Dartfish® system | 1 minute after intervention | 
| Angular velocity values | Angular velocity values will be calculated with the Dartfish® system | 1 minute after intervention | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mean amplitude of the two groups |  | 1 minute after intervention | 
| Mean angular velocity of the two groups |  | 1 minute after intervention | 
| Mean amplitude after mobilization with thumb abduction |  | 1 minute after intervention | 
| Mean angular velocity after mobilization with thumb abduction |  | 1 minute after intervention | 
| Mean amplitude after mobilization of the fifth finger |  | 1 minute after intervention | 
| Mean angular velocity after mobilization of the fifth finger |  | 1 minute after intervention | 
| Pain experienced by stroke patients before mobilisation | Pain will be assessed by the Visual Analogue Scale (VAS) | 1 minute before intervention | 
| Pain experienced by stroke patients after mobilisation | Pain will be assessed by the Visual Analogue Scale (VAS) | 1 minute after intervention | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Mobilization, Muscle Spasticity, Wrist and Hand Complex