Quantitative Evaluation of Apathy Close to Real Life Situation by Means of a Multimodal Sensor System Integrated.

Study Overview
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Brief Summary
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The purpose of this study is to provide relevant quantitative evaluation of apathy close to real life situation by means of a multimodal sensor system integrated.

Detailed Description
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The investigators try to measure the amount of goal-directed behaviour and to detect the pattern of apathy. The main objective of this pilot phase is to select the variables of goal-directed behaviour from the list of metrics providing by the multimodal acquisition system in healthy subjects and patients with frontotemporal dementia.

Official Title
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Quantitative Evaluation of Apathy Close to Real Life Situation by Means of a Multimodal Sensor System Integrated in Healthy Subjects and Patients With Frontotemporal Dementia. Pilot Phase.

Conditions
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Apathy, Behavior, Frontotemporal Dementia

Intervention / Treatment
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* Behavioral: Evaluation of Apathy Close to Real Life Situation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Diagnosis of Frontotemporal Dementia (FTD) according to diagnostic criteria reported by Rascovsky et al. (2011). Understanding of the instructions and capacity to realize the cognitive tasks. Capacity to read, to understand and to sign legal document of information Capacity for informed consent for research, capacity to sign consent MMSE score > 20 Absence of other cerebral pathology. Absence of psychiatric disease interfering with the assessment of the tests Absence of excessive psychotropic use Access to National Healthcare Insurance Accompanied with a caregiver Exclusion Criteria: Excessive psychotropic use Incapacity or refusal to realize the experimental tasks Subject deprived of freedom by an administrative or court order Subject under legal protective measure. Incapacity for informed consent for research Participation in another biomedical research Airway obstruction risk Reduction of activity not attributable to another chronic pathological condition

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: ECOCAPTURE<br>Quantitative Evaluation of Apathy Close to Real Life Situation by Means of a Multimodal Sensor System Integrated. | Behavioral: Evaluation of Apathy Close to Real Life Situation<br>* Quantitative Evaluation of Apathy Close to Real Life Situation by Means of a Multimodal Sensor System Integrated.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Occurrence of each behavior from the ethogram | [Provided by the video recording and The Observer NOLDUS software] | 45 min | 
| Frequency of each behavior from the ethogram | [Provided by the video recording and The Observer NOLDUS software] | 45 min | 
| Duration of each behavior from the ethogram | [Provided by the video recording and The Observer NOLDUS software] | 45 mn | 
| Number of different behaviors | [Provided by the video recording and The Observer NOLDUS software] | 45 mn | 
| Activity classes | [Provided by the MOVE MOVISENS sensor] lying, sitting, ... | 45 mn | 
| Body positions | [Provided by the MOVE MOVISENS sensor] lying left, ... | 45 mn | 
| Energy expenditure | [Provided by the MOVE MOVISENS sensor] kcal. | 45 mn | 
| MET | [Provided by the MOVE MOVISENS sensor] The Metabolic Equivalent of Task. MET level. | 45 mn | 
| Steps | [Provided by the MOVE MOVISENS sensor] Counting steps. | 45 mn | 
| Activity intensity | [Provided by the MOVE MOVISENS sensor] g. | 45 mn | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Apathy, Goal-directed behavior, Quantitative evaluation, Sensor, Ethogram