Dual Diagnosis (Psychosis and Cannabismisuse): Comparison of Specialized Treatment Versus Unspecified Treatment

Study Overview
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Brief Summary
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Intention of the study is to examine, if the symptomatology of dual diagnosis patients is less severe after a special indication training for reduction of cannabis consumption in comparison to unspecified trainings. Point of interest is psychopathology and consumerism.

Detailed Description
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Dual diagnosis patients (psychosis and cannabis abuse) account for more clinical admissions than single diagnosis patients. Cannabis misuse is a known risk factor for recurrence of psychosis. A specified intervention on the basis of a manual for schizophrenic substance abusers is administered to inpatients in a specialized unit for young schizophrenic patients in a psychiatric hospital. The control group, same indication (psychotic disorder and cannabis misuse) receives social competence training (specified for schizophrenic patients as well). Admission to groups is randomly.

Official Title
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Dual Diagnosis Psychosis and Substance Abuse: Short- and Middle-term Changes in Symptomatology After Visiting a Group Education Programme to Reduce Consumption of Cannabis

Conditions
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Psychotic Disorders, Marijuana Abuse, Intervention

Intervention / Treatment
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* Behavioral: Cannabis-Consumption-Reduction-Training
* Behavioral: Social competence Training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Clinical diagnosis of schizophrenia and disorders with psychotic features Misuse of cannabis during 12 months preceding admission to hospital Exclusion Criteria: Not able to attend training twice a week for 45 minutes (concentration, attention, psychotic symptoms, agitation) Discharge from hospital before completion of training

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: ACT<br>Anti-Cannabis-Consumption-Training | Behavioral: Cannabis-Consumption-Reduction-Training<br>* 8 sessions within 4 weeks (twice a week, 45 minutes each) Cognitive behavioral therapy with focus on cannabis abuse<br>|
| Active Comparator: CG<br>Control group | Behavioral: Social competence Training<br>* 8 sessions within 4 weeks (twice a week, 45 minutes) training to develop and ameliorate social competences<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| PANSS Positive and Negative Symptom Scale |  | post intervention, six months follow-up | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Urinstatus for cannabinoids |  | weekly during and post intervention, follow-up | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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psychotic disorders, cannabis, intervention