Effects of C-MAC Videolaryngoscope, McGRATH Videolaryngoscope and Macintosh Direct Laryngoscope on Intraocular Pressure and Hemodynamics

Study Overview
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Brief Summary
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In this study, participants aimed to compare the effects of direct laryngoscopic endotracheal intubation and videolaryngoscopic intubation with C-MAC videolaryngoscope and McGrath videolaryngoscope on intraocular pressure and hemodynamics.

Detailed Description
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The maintenance of airway opened is one of the main responsibility of the anesthetist. Intubation procedure during anesthesia application benefits such as airway opening, airway and breathing control, aspiration hazard, respiratory effort and dead space reduction, surgical comfort and airway control during resuscitation. Laryngoscopy and tracheal intubation increases in heart rate, blood pressure and the intraocular pressure. The sympathetic-adrenal activity caused by the stimulation of the laryngeal and tracheal tissues is responsible for these negative effects. Endotracheal intubation with videolaryngoscopy is an alternative method used in airway management. Laryngoscopy and tracheal intubation under general anesthesia and laryngeal mask and airway control techniques cause different hemodynamic and catecholamine levels.

Official Title
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Effects of C-MAC Videolaryngoscope, McGRATH Videolaryngoscope and Macintosh Direct Laryngoscope on Intraocular Pressure and Hemodynamics; a Randomized, Double-blind Clinical Trial

Conditions
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Anesthesiology Devices Associated With Adverse Incidents, Intraocular Pressure

Intervention / Treatment
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* Device: Direct laryngoscope
* Device: C-MAC videolaryngoscope
* Device: McGrath videolaryngoscope


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: American Society of Anesthesiologist Score 1-2 Mallampati 1 ve 2 Exclusion Criteria: Glaucoma, Diabetes mellitus Cardiovascular and pulmonary disease American Society of Anesthesiologist Score III-IV Bdoy mass index greater than 35 Difficult intubation history Obstetric surgery Propofol, fentanyl, rocuronium contraindication

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Prospective, Randomized, double blind Clinical Trial
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: direct laryngoscope<br>Endotracheal intubation was applied by anesthesiologist with direct laryngoscope. | Device: Direct laryngoscope<br>* Endotracheal intubation was applied by anesthesiologist wtih direct laryngoscope. SAP (systolic arterial pressure), DAP (diastolic arterial artery pressure), MAP (mean arterial pressure) were measured before and 5 minutes after intubation, , Heart rate (HR), SPO2 (oxygen saturation by pulse oximetry), PI (perfusion index), and intraocular pressure values measured by the eye clinician using the device.<br>Device: C-MAC videolaryngoscope<br>* Endotracheal intubation was applied by anesthesiologist wtih direct laryngoscope. SAP (systolic arterial pressure), DAP (diastolic arterial artery pressure), MAP (mean arterial pressure) were measured before and 5 minutes after intubation, , Heart rate (HR), SPO2 (oxygen saturation by pulse oximetry), PI (perfusion index), and intraocular pressure values measured by the eye clinician using the device.<br>Device: McGrath videolaryngoscope<br>* Endotracheal intubation was applied by anesthesiologist wtih direct laryngoscope. SAP (systolic arterial pressure), DAP (diastolic arterial artery pressure), MAP (mean arterial pressure) were measured before and 5 minutes after intubation, , Heart rate (HR), SPO2 (oxygen saturation by pulse oximetry), PI (perfusion index), and intraocular pressure values measured by the eye clinician using the device.<br>|
| Active Comparator: C-MAC videolaryngoscope<br>Endotracheal intubation was applied by anesthesiologist with C-MAC videolaryngoscope. | Device: Direct laryngoscope<br>* Endotracheal intubation was applied by anesthesiologist wtih direct laryngoscope. SAP (systolic arterial pressure), DAP (diastolic arterial artery pressure), MAP (mean arterial pressure) were measured before and 5 minutes after intubation, , Heart rate (HR), SPO2 (oxygen saturation by pulse oximetry), PI (perfusion index), and intraocular pressure values measured by the eye clinician using the device.<br>Device: C-MAC videolaryngoscope<br>* Endotracheal intubation was applied by anesthesiologist wtih direct laryngoscope. SAP (systolic arterial pressure), DAP (diastolic arterial artery pressure), MAP (mean arterial pressure) were measured before and 5 minutes after intubation, , Heart rate (HR), SPO2 (oxygen saturation by pulse oximetry), PI (perfusion index), and intraocular pressure values measured by the eye clinician using the device.<br>Device: McGrath videolaryngoscope<br>* Endotracheal intubation was applied by anesthesiologist wtih direct laryngoscope. SAP (systolic arterial pressure), DAP (diastolic arterial artery pressure), MAP (mean arterial pressure) were measured before and 5 minutes after intubation, , Heart rate (HR), SPO2 (oxygen saturation by pulse oximetry), PI (perfusion index), and intraocular pressure values measured by the eye clinician using the device.<br>|
| Active Comparator: McGrath videolaryngoscope<br>Endotracheal intubation was applied by anesthesiologist with McGrath videolaryngoscope. | Device: Direct laryngoscope<br>* Endotracheal intubation was applied by anesthesiologist wtih direct laryngoscope. SAP (systolic arterial pressure), DAP (diastolic arterial artery pressure), MAP (mean arterial pressure) were measured before and 5 minutes after intubation, , Heart rate (HR), SPO2 (oxygen saturation by pulse oximetry), PI (perfusion index), and intraocular pressure values measured by the eye clinician using the device.<br>Device: C-MAC videolaryngoscope<br>* Endotracheal intubation was applied by anesthesiologist wtih direct laryngoscope. SAP (systolic arterial pressure), DAP (diastolic arterial artery pressure), MAP (mean arterial pressure) were measured before and 5 minutes after intubation, , Heart rate (HR), SPO2 (oxygen saturation by pulse oximetry), PI (perfusion index), and intraocular pressure values measured by the eye clinician using the device.<br>Device: McGrath videolaryngoscope<br>* Endotracheal intubation was applied by anesthesiologist wtih direct laryngoscope. SAP (systolic arterial pressure), DAP (diastolic arterial artery pressure), MAP (mean arterial pressure) were measured before and 5 minutes after intubation, , Heart rate (HR), SPO2 (oxygen saturation by pulse oximetry), PI (perfusion index), and intraocular pressure values measured by the eye clinician using the device.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| intraocular pressure | The relevant values will be measured in the determined time. | From beginning of Anesthesia to 10th minute of surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| systolic arterial pressure | The relevant values will be measured in the determined time. | From beginning of Anesthesia to 10th minute of surgery | 
| diastolic arterial pressure | The relevant values will be measured in the determined time. | From beginning of Anesthesia to 10th minute of surgery | 
| heart rate | The relevant values will be measured in the determined time. | From beginning of Anesthesia to 10th minute of surgery | 
| peripheral oxygen saturation | The relevant values will be measured in the determined time. | From beginning of Anesthesia to 10th minute of surgery | 
| mean arterial pressure | The relevant values will be measured in the determined time. | From beginning of Anesthesia to 10th minute of surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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tracheal intubation, videolaryngoscopy, hemodynamics, intraocular pressure