Internet-delivered CBT for Adolescents With Obsessive-Compulsive Disorder - a Pilot Study

Study Overview
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Brief Summary
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The main goal of this trial is to study the feasibility and effectiveness of internet-delivered cognitive behavior therapy for adolescents with obsessive-compulsive disorder.

Official Title
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Internet-delivered Cognitive Behavior Therapy for Adolescents With Obsessive-Compulsive Disorder - a Pilot Study

Conditions
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Obsessive-Compulsive Disorder

Intervention / Treatment
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* Behavioral: Internet-delivered Cognitive Behavior Therapy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: a primary diagnosis of OCD as defined by DSM-IV TR a total score of above 15 on the CY-BOCS age between 12 and 17 years ability to read and write Swedish daily access to the internet a parent that is able to co-participate in the treatment Participants on psychotropic medication must have been on a stable dose for the last 6 weeks prior to baseline assessment signed informed consent Exclusion Criteria: diagnosed autism spectrum disorder, psychosis or bipolar disorder suicidal ideation ongoing substance dependence subject not able to read or understand the basics of the ICBT self-help material completed CBT for OCD within last 12 months (defined as at least 5 sessions CBT including exposure and response prevention) ongoing psychological treatment for OCD or another anxiety disorder

Ages Eligible for Study
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Minimum Age: 12 Years
Maximum Age: 17 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: internet-delivered cognitive behavior therapy<br>Participants will be assigned to a 12 weeks internet-delivered cognitive behavior therapy program including therapist contact via an internet platform and telephone. | Behavioral: Internet-delivered Cognitive Behavior Therapy<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Children's Yale Brown Obsessive Compulsive Scale, CY-BOCS | Change from Baseline of obsessions and compulsions after 12 weeks and at 3- and 6 months after treatment. | Baseline, 12 weeks after treatment starts, 3 and 6 months after treatment has ended | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Spence Child Anxiety Scale - Child and Parent version | Spence Child Anxiety Scale - Child and Parent version (SCAS/P, Spence, 1998) will be used as a child and parent self-report measure of anxiety related psychopathology. | Baseline, 12 weeks after treatment starts, 3 and 6 months after treatment has ended | 
| Child Depression Inventory | Symptom severity of depression in the adolescent will be assessed with Child Depression Inventory (CDI, Kovacs, 1985). | Baseline, 12 weeks after treatment starts, 3 and 6 months after treatment has ended | 
| Strengths Difficulties Questionnaire | Strengths Difficulties Questionnaire (SDQ, Goodman, 1997) is a widely used self- and parent-report behavioral screening questionnaire with six subscales: emotional problems, conduct problems, hyperactivity-inattention, peer problems, prosocial behavior | Baseline, 12 weeks after treatment starts, 3 and 6 months after treatment has ended | 
| Children's Obsessional Compulsive Inventory Revised | The Children's Obsessional Compulsive Inventory Revised, (CHOCI-R, Shafran et al., 2003) is a self- and parent-report measure of pediatric OCD symptom severity. | Baseline, 12 weeks after treatment starts, 3 and 6 months after treatment has ended | 
| Child Obsessive-Compulsive Impact Scale - Revised | Child Obsessive-Compulsive Impact Scale - Revised (COIS-R, Piacentini, Peris, Bergman, Chang, & Jaffer, 2007) is a self- and parent-report scale of OCD symptom impact on everyday life. | Baseline, 12 weeks after treatment starts, 3 and 6 months after treatment has ended | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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cognitive behavior therapy, pediatric obsessive-compulsive disorder, internet-delivered cognitive behavior therapy