Topical Lidocaine After Major Arthroscopic Knee Surgery

Study Overview
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Brief Summary
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Pain after major arthroscopic surgery is dependent on an optimal multimodal analgesic treatment.

Detailed Description
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Lidocaine is well-known as analgesic treatment on skin and hypodermic veins. Since 1996 it has been documented that topical lidocaine has an analgesic effect 24 hours after surgical treatment. The aim is to determine a possible reduction in pain after knee arthroscopy with topical lidocaine.

Official Title
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Topical Lidocaine Patch Does Not Have an Analgesic Effect After Major Arthroscopic Knee Surgery. A Double-blind Place-controlled Randomized Study

Conditions
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Fracture of Patella, Pain

Intervention / Treatment
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* Procedure: Sham operation
* Procedure: Knee arthroscopic surgery


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients who were planned for reconstruction of anterior crucial ligament, reconstruction of medial patellofemoral ligament and Elmslie-Trillat procedure for patella instability. Patients with synovectomies and menisci resection lasting more than 25 minutes. Patients > 18 years Acceptance of informed consent Exclusion Criteria: Patients with rheumatoid arthritis Patients with a Body Mass index of > 35 Patients who can not read and understand Danish Fertile women who does not use secure contraception

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Placebo Comparator: Sham operation<br> | Procedure: Sham operation<br>* A randomized group of patients received a placebo patch. As a supplement, each patient was given a dose of morphine, as required.<br>* Other names: Knee soft-tissue;|
| Active Comparator: Knee arthroscopic surgery<br> | Procedure: Knee arthroscopic surgery<br>* A randomized group of patients was given small patches with active 5% lidocaine.<br>* Other names: Knee soft-tissue;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Administration of analgesic drugs | Time for the first necessary administration of analgesic drugs. | 24 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain management after surgical treatment | The intake of necessary analgesic drugs after 6, 12, 18 and 24 hours after surgical treatment. Pain score according to the VAS scale when the patients rest and make movements. | 24 hours | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Knee, Arthroscopy, Lidocaine patch, Pain management after knee arthroscopy