linjc16/ctgov huggingface dataset:
The Effect of Menopause on Sexual Life and Depression: a Case-control Study.

Study Overview
=================
Brief Summary
-----------------
work completed but not yet published

Detailed Description
-----------------
work completed but not yet published

Official Title
-----------------
The Effect of Menopause on Sexual Life and Depression: a Case-control Study.

Conditions
-----------------
Menopause, Depression, Sexual Dysfunction

Intervention / Treatment
-----------------
* Other: Case control


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Case group: Women between the ages of 45-65, who are in the postmenopausal period, who are literate, who do not have communication difficulties / mental disabilities, and who volunteer to participate in the study were included. Control Group: Women between the ages of 45-55, who were not menopausal, who were literate, who had no communication difficulties / mental disabilities and who volunteered to participate in the study were included. Exclusion Criteria: For case group: Women with premature menopause (before the age of 40), chronic systemic disease (diabetes, heart disease, hypertension, thyroid, rheumatic disease, psychiatric disease history) and using psychiatric drugs were not included in the study. For control group: Women under the age of 45, over the age of 55 with chronic systemic diseases (diabetes, heart disease, hypertension, thyroid, rheumatic disease, psychiatric disease history) and using psychiatric drugs were not included in the study.

Ages Eligible for Study
-----------------
Minimum Age: 45 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
Female

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Case group<br>Women who have entered early menopause (before the age of 40), have chronic systemic diseases (diabetes, heart disease, hypertension, thyroid, rheumatic disease, psychiatric disease history), and use psychiatric drugs were not included in the study. | Other: Case control<br>* Case control study<br>|
| Control group<br>Women under the age of 45, over the age of 55 with chronic systemic diseases (diabetes, heart disease, hypertension, thyroid, rheumatic disease, psychiatric disease history) and using psychiatric drugs were not included in the study. | Other: Case control<br>* Case control study<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The effect of menopause on sexual life and depression: a case-control study. | Data completed in April 2019 | 14.01.2019-16.02.2021 |
Accuracy of SpO2 for Noninvasive Pulse Oximeter Sensor (LNCS ADTX)

Study Overview
=================
Brief Summary
-----------------
In this study, the level of oxygen within the blood will be reduced in a controlled manner by reducing the concentration of oxygen the study volunteer breathes. The accuracy of a noninvasive pulse oximeter sensor will be assessed by comparison to the oxygen saturation measurements from a laboratory blood gas analyzer.

Conditions
-----------------
Healthy

Intervention / Treatment
-----------------
* Device: LNCS ADTX Sensor


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Competent non-smoking adults between the ages of 18 and 40 for each series of tests. Subjects must understand and consent to be in the study. American Society of Anesthesiology Class 1 (Healthy subjects without any systemic disease at all). Exclusion Criteria: Subjects who have any systemic disease at all. Subjects who do not understand the study and the risks. Smokers. Subjects who are pregnant. Subjects having either signs or history of peripheral ischemia. Others deemed ineligible by the clinical staff.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 40 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Other
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Test Subject<br>All subjects are enrolled into the test group and receive the LNCS ADTX Sensor. | Device: LNCS ADTX Sensor<br>* Noninvasive pulse oximeter sensor.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Accuracy of Sensor by Arms Calculation | Accuracy will be determined by comparing the noninvasive blood oxygen saturation measurement of the pulse oximeter to that obtained from a blood sample and calculating the arithmetic root mean square error (Arms) value. In order to obtain the Arms value, the blood oxygen saturation measurement is subtracted from the pulse oximeter oxygen saturation measurement for a number of samples, the average of this difference is computed as the bias. The standard deviation of the differences is computed as the precision. The square root of the sum of the squares of bias and precision is computed as the Arms Error value. | 1-5 hours |
Chronic Pain After Thoracotomy, an Incidence Study

Study Overview
=================
Brief Summary
-----------------
This is an investigation on the frequency of chronic pain after thoracotomy for lung cancer. Factors relating to the development of chronic pain are investigated. Questionnaire survey.

Official Title
-----------------
Chronic Pain After Thoracotomy, an Incidence Study

Conditions
-----------------
Thoracotomy, Chronic Pain

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Able to understand and give consent Can read Residing in Denmark Exclusion Criteria: Unable to understand the written information in Danish Abuse (Medicine, Drugs, Alcohol) Severe psychiatric Illness Conflicting neurological disease

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain and pain score |  | more than 6 months postoperative | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Activity of daily life |  | >6 months | 
| Analgesic consumption and pain treatment |  | >6 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Thoracotomy, Chronic Pain
Cardiac Surgery Outcomes in Blood-transfusion Acceptors and no Acceptors

Study Overview
=================
Brief Summary
-----------------
The primary objective of this study is to analyze mortality after cardiac surgery in blood-transfusion non-acceptors (BTNA), and the secondary one to perform an adjusted comparison with a blood-transfusion acceptors (BTA) matched cohort.

Official Title
-----------------
Cardiac Surgery Outcomes in Blood-transfusion Acceptors and no Acceptors: a Retrospective Cohort Study

Conditions
-----------------
Thoracic Surgery, Blood Transfusion; Hemoglobinemia, Cardiac Disease

Intervention / Treatment
-----------------
* Other: Non-acceptance of blood-transfusions
* Other: Acceptance of blood-transfusions


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients undergoing heart surgery in our hospital from 2009 to June 2020 Exclusion Criteria: Preoperative hemoglobin lower than 120g/L EuroSCORE-II higher than 20% Heart transplant Assist device implantation Surgery of acute myocardial infarction-derived complications Other emergent cardiac surgeries (acute aortic dissection, heart injuries).

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 100 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Blood-transfusion non-acceptors<br>Blood-transfusion non-acceptors | Other: Non-acceptance of blood-transfusions<br>* Patients who do not accept blood products transfusions<br>|
| Blood-transfusion acceptors<br>Blood-transfusion acceptors | Other: Acceptance of blood-transfusions<br>* Patients who accept blood products transfusions<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change on Hemoglobin values from preoperative to end-of-surgery levels | Changes on Hemoglobin values in percentage from preoperative level to the end of the surgery level | End-of-surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rate of operative mortality | Any death occurring i) within the first 30 postoperative days in or out of the hospital, and ii) after 30 days during the same hospitalization subsequent to the operation. | At discharge or within the first 30 postoperative days | 
| Intraoperative fluid balance | Resting the fluid outputs to inputs | End of surgery | 
| Hemoglobin at discharge | Hemoglobin level at discharge | At discharge, an average of 10 days | 
| Rate of postoperative morbidity | Postoperative complications: hemodynamic, respiratory, renal, neurological, infective complications | At discharge, an average of 10 days |
A Trial Evaluating the Blood Glucose-lowering Effect of NN1250 in Subjects With Type 2 Diabetes

Study Overview
=================
Brief Summary
-----------------
This trial was conducted in Europe. The aim of this clinical trial was to evaluate the blood glucose-lowering effect of NN1250 (insulin degludec/insulin 454) in subjects with type 2 diabetes.

Official Title
-----------------
A Trial Evaluating the Pharmacodynamic Response of NN1250 at Steady State in Subjects With Type 2 Diabetes

Conditions
-----------------
Diabetes, Diabetes Mellitus, Type 2

Intervention / Treatment
-----------------
* Drug: insulin degludec


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Type 2 diabetes mellitus (as diagnosed clinically) for at least 12 months Body mass index (BMI) below or equal to 35.0 kg/m2 Exclusion Criteria: Subject who has donated any blood or plasma in the past month or more than 500 mL within 3 months prior to screening Smoker (defined as a subject who is smoking more than 5 cigarettes or the equivalent per day) Not able or willing to refrain from smoking and use of nicotine gum or transdermal nicotine patches during the inpatient period

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: IDeg 100U/mL 0.4U/kg<br> | Drug: insulin degludec<br>* Insulin degludec (IDeg) injected s.c. (under the skin) once daily for 6 days in each treatment period. Each subject was randomly allocated to 2 out of 4 treatments.<br>|
| Experimental: IDeg 100U/mL 0.6U/kg<br> | Drug: insulin degludec<br>* Insulin degludec (IDeg) injected s.c. (under the skin) once daily for 6 days in each treatment period. Each subject was randomly allocated to 2 out of 4 treatments.<br>|
| Experimental: IDeg 100U/mL 0.8U/kg<br> | Drug: insulin degludec<br>* Insulin degludec (IDeg) injected s.c. (under the skin) once daily for 6 days in each treatment period. Each subject was randomly allocated to 2 out of 4 treatments.<br>|
| Experimental: IDeg 200U/mL 0.6U/kg<br> | Drug: insulin degludec<br>* Insulin degludec (IDeg) injected s.c. (under the skin) once daily for 6 days in each treatment period. Each subject was randomly allocated to 2 out of 4 treatments.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Area under the glucose infusion rate curve from 0-24 hours at steady state |  | 0-24 hours (derived on treatment day 6) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Area under the insulin degludec concentration-time curve from 0-24 hours at steady state |  | 0-24 hours (derived on treatment day 6) |
Large Burn Outcome Study

Study Overview
=================
Brief Summary
-----------------
To examine long term physical and psychosocial outcomes of pediatric burn survivors. We want to learn about thoughts, feelings, coping style, social support, and overall adjustment following burn injury.

Detailed Description
-----------------
To evaluate the long term quality of life of adolescents and adults who suffered severe pediatric burns. This study will include an array of physical and psychosocial assessments, thus providing a unique and complete set of information on the long term outcomes in this population.

Official Title
-----------------
Assessment of the Treatment of the Severely Burned With Anabolic Agents on Improved Wound Healing, Recovery and Rehabilitation: Large Burn Outcome Study

Conditions
-----------------
Burns

Intervention / Treatment
-----------------
* Procedure: Blood and urine testing


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: At least 60% third degree total body surface area Acute burn treatment at Shriners Burns Hospital for Children - Galveston between 1986-2005 Three years post injury Current age of at least 16 years Exclusion Criteria:

Ages Eligible for Study
-----------------
Minimum Age: 16 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: Blood and urine testing|complete blood count, routine chemistries, liver function test, retinol binding protein, transferrin, prothrombin time, partial thromboplastin time, fibrinogen, Vitamin A and Zinc, Insulin Growth Factor levels and binding proteins, cytokines (interleukins 1, 6, 12), insulin, thyroid hormones, cortisol, 25-hydroxyvitamin D, and osteocalcin.|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Burn injury, Burn recovery
A Modified Technique to Facilitate Pealing of the Rectal Mucosa in Delorme Operation

Study Overview
=================
Brief Summary
-----------------
The aim of this study is to evaluate the investigator new modification for delorme procedure in patients with rectal prolapse , assessing intra-operative morbidity and recurrence rate .

Detailed Description
-----------------
In classic delorme operation stripping of the mucosa done and this is associated with extensive bleeding in addition to the time consumed in this step.the new modification done by the investigator replace this step with another associated with less intraoperative bleeding and not time consuming.

Conditions
-----------------
Rectal Prolapse

Intervention / Treatment
-----------------
* Procedure: Modified delorme procedure


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Mild to moderate rectal prolapse Singed informed consent. Exclusion Criteria: Huge rectal prolapse . Recurrent rectal prolapse
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Modified Delorme<br>Modified technique for delorme procedure done in mild to moderate rectal prolapse as the investigator destroy use the electrocautery to peal the mucosa with less intraoperative bleeding ,avoiding stripping of the mucosa done in classic delorme that induce major bleeding intraoperative . | Procedure: Modified delorme procedure<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Recurrence rate assessed in this modified technique |  | One year follow up post operative | 
| intraoperative bleeding measured in this modified technique |  | one year follow up post operative. | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Recta prolapse, Intraoperative bleeding, mucosal cauterization
Conventional One-piece Versus Two-piece Magnet-retained Obturators

Study Overview
=================
Brief Summary
-----------------
Evaluation of patients' satisfaction with conventional one-piece obturators versus two pieces magnet -retained obturators in completely edentulous patient maxillectomy cases.

Detailed Description
-----------------
Ten completely edentulous participants with hemimaxillectomy (8 males and 2 females) were selected in an across over study. Participants received conventional obturator one piece and two pieces obturator connecting by magnet attachment in alternate periods (sequences A-B and B-A), and outcomes were assessed after 1 week,3 months, and 6 months Evaluation included Obturator Functioning Scale(OFS) and Oral Health Impact Profile for edentulous people (OHIP-EDENT ). One way ANOVA test and Multivariate analysis of variance with a general linear model with repeated measure was used to test the impact of the group, time, and order on each of the studied scores (α=.05).

Official Title
-----------------
Patient Satisfaction of Conventional One-piece Versus Two-piece Magnet-retained Obturators for Patients With Complete Edentulism: A Crossover Study

Conditions
-----------------
Patient Satisfaction

Intervention / Treatment
-----------------
* Other: two pieces obturator


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: - completely edentulous participants with hemimaxillectomy mouth opening is not less than 25 mm and intact soft palate Exclusion Criteria: exposed to radiotherpy
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: conventional obturator<br>Participants received conventional obturator one piece | Other: two pieces obturator<br>* patient received two pieces obturator connecting by magnet attachment<br>* Other names: sectional obturator;|
| Experimental: sectional obturator<br>two pieces obturators connected by magnet attachments | Other: two pieces obturator<br>* patient received two pieces obturator connecting by magnet attachment<br>* Other names: sectional obturator;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| patient satisfaction | evaluation of satisfaction by Obturator Functioning Scale(OFS) | 1 week to 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| patient satisfaction | evaluation of satisfaction by Oral Health Impact Profile for edentulous people (OHIP-EDENT ) | 1 week to 6 months |
Effect of Heat Stress on Global LV Function in Anesthetized Humans

Study Overview
=================
Brief Summary
-----------------
Recent data suggests that increased temperature improves inotropic function during systole and may improve diastolic function in healthy humans at rest, despite a reduction in left ventricular volume at end diastole. The effect of heat stress has not been reported in patients receiving general anesthesia and the impact of general anesthesia on these findings is not known. Trans-esophageal echocardiography will be used to measure parameters important to both systolic and diastolic function at temperature intervals of 1°C in patients undergoing Heated Intraoperative Peritoneal Chemotherapy (HIPEC.) That general anesthesia will not alter the cardiovascular effects of increased temperature that has been reported in healthy, un-anesthetized humans is the hypothesis.

Official Title
-----------------
Effect of Heat Stress on Global LV Function in Anesthetized Humans

Conditions
-----------------
Hyperthermia, Cardiac Functional Disturbances During Surgery

Intervention / Treatment
-----------------
* Diagnostic Test: Transesophageal Echocardiography


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: any patient presenting for hyperthermic intraperitoneal chemotherapy. Exclusion Criteria: Subjects less than 18 years old. pregnant women prisoners, institutionalized individuals Any patient with known contraindication to Transesophageal echocardiography. Patients with known cardiac dysfunction prior to screening will be excluded.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Supportive Care
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: Transesophageal Echocardiography|Placement of a transesophageal probe and performance of a diagnostic Transesophageal echocardiography examination.|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in ejection fraction before and after hyperthermia |  | Approximately 6 hours from prior to hyperthermia to during hyperthermia. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Transmitral inflow velocities before and after hyperthermia |  | Approximately 6 hours from prior to hyperthermia to during hyperthermia. | 
| Pulmonary venous inflow velocities before and during hyperthermia |  | Approximately 6 hours from prior to hyperthermia to during hyperthermia. | 
| Mitral annular tissue doppler velocities before and during hyperthermia |  | Approximately 6 hours from prior to hyperthermia to during hyperthermia. |