Effect of Warm Saline Irrigation on Bleeding in Mandibular Third Molar Surgery

Study Overview
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Brief Summary
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The objective of this research is to compare the effect of irrigation during impacted mandibular third molar surgery, with normal saline of 25 ± 2 ° C and 37 ± 1 ° C for control and experimental sides, respectively.

Detailed Description
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The objective of this research is to compare the effect of irrigation during impacted mandibular third molar surgery, with normal saline of 25 ± 2 ° C and 37 ± 1 ° C for control and experimental sides, respectively. For this purpose, 40 mandibular impacted third molars will be randomly allocated to two groups and surgically removed with the abovementioned saline temperatures. Finally, the suctioned liquids and duration of the surgeries will be carefully measured and compared between both sides.

Official Title
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The Effect of Warm Saline Irrigation on the Amount of Bleeding in Impacted Mandibular Third Molar Surgery: a Split-mouth Single-blinded Randomized Controlled Clinical Trial

Conditions
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Surgical Blood Loss, Third Molar

Intervention / Treatment
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* Procedure: warm saline irrigation


Participation Criteria
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Eligibility Criteria
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Inclusion criteria Being a candidate for bilateral mandibular third molar surgery Both mandibular third molars must have a similar inclination to the second molar Both mandibular third molars must have same Pell & Gregory's classification Exclusion criteria Presence of any systemic condition or using any type of medication History of allergy to local anesthetic (LA) solutions Patients with an active gag reflex Pregnant and post-menopause women Patients with pericoronitis or any local inflammation
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Warm saline<br>this site was irrigated during impacted mandibular third molar surgery, with normal saline of 37 ± 1 ° C as for the experimental side. | Procedure: warm saline irrigation<br>* The objective of this research was to compare the effect of irrigation during impacted mandibular third molar surgery, with normal saline of 25 ± 2 ° C and 37 ± 1 ° C for control and experimental sides, respectively.<br>|
| No Intervention: Room temperature saline<br>this site was irrigated during impacted mandibular third molar surgery, with normal saline of 25 ± 2 ° C as for the control side. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Amount of Bleeding in Cubic Centimetre | both sides will be irrigated with 200cc of saline and the suctioned liquids will be carefully measured and compared | Intraoperatively, up to 30 minutes | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Duration of the Surgery in Minutes | both sides will be irrigated with 200cc of saline and the duration of the surgeries will be carefully measured and compared between both sides | Intraoperatively, up to 30 minutes | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Warm Saline