The Effect of Omega 3 on 25 Hydroxyvitamin D

Study Overview
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Brief Summary
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The effect of omega 3 fatty acid on serum 25-hydroxyvitamin D levels.

Detailed Description
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No data are available on the effect of omega 3 on serum 25-hydroxyvitamin D levels in Jordanian men and women. This study was designed to investigate whether omega 3 supplementation has a potential effect on the reducing of serum 25-hydroxyvitamin D levels. This randomized, placebo-controlled clinical trial (RCT) was designed to evaluate 300 mg omega-3FA daily for 2 months on serum levels of 25-hydroxyvitamin D levels. This RCT will be conducted on 80 to 90 Jordanian men and women aged 22 to 66 years. Baseline and follow-up levels for 25-hydroxyvitamin D (25OHD), parathyroid hormone (PTH), calcium, phosphate, liver and kidney functions will be assayed.

Official Title
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The Effect of Omega 3 Supplementations on Serum 25 Hydroxyvitamin D Levels

Conditions
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25-hydroxyvitamin D Levels

Intervention / Treatment
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* Dietary Supplement: Dietary Supplement: Omega3-FA


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age ≥18 years old Male and female Jordanian ASU students and employees who live in Amman. Informed written consent from the participant prior to the start of the study. a serum 25(OH)D concentration between 10 and 70 ng/mL. Exclusion Criteria: Any eligiable subject refuses to apply with informed written consent before the start of the study. Men or women previously diagnosed with chronic diseases, including kidney disease or GIT problems. Who are receiving vitamin D3 supplements (3 months before the start of the study) . Pregnants,Breastfeeding females ,Females using hormonal contraceptives

Ages Eligible for Study
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Minimum Age: 22 Years
Maximum Age: 66 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Omega3-FA group<br>Omega3-FA group 1000 mg wild salmon and fish oil complex (contains 300 mg of omega3-FA) once daily | Dietary Supplement: Dietary Supplement: Omega3-FA<br>* Dietary Supplement: Omega3-FA 300 mg of omega3-FA once daily for 8 weeks<br>* Other names: n-3FA;|
| Experimental: Control group<br>VD3 group 50,000 IU/week | Dietary Supplement: Dietary Supplement: Omega3-FA<br>* Dietary Supplement: Omega3-FA 300 mg of omega3-FA once daily for 8 weeks<br>* Other names: n-3FA;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| serum concentrations of 25-hydroxyvitamin D | ng/ml | 8 weeks | 
| serum concentrations of PTH | pg/mL | 8 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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omega 3, 25 hydroxyvitamin D, 25OHD, Vitamin D