Volume and Attachment Changes in Autotransplanted Closed Apex Permanent Teeth

Study Overview
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Brief Summary
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The aim of this prospective observational investigation is to evaluate the dimensional and attachment changes occurring in the treated areas and in the autotransplanted teeth respectively of adult patients with permanent teeth with closed apex.

Detailed Description
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Dental autotransplantation has high success rates in permanent teeth with open apex. The success results in permanent teeth with closed apex are somewhat lower but sufficient to consider the treatment as a viable alternative and to extend the therapeutic range of the treatment to older ages. The aim of this prospective observational investigation is to evaluate the dimensional and attachment changes occurring in the treated areas and in the autotransplanted teeth respectively of adult patients with permanent teeth with closed apex. All adult patients receiving a dental autotransplantation between July 2022 and January 2024 will be included. Pre-treatment, volume and attachment parameters will be recorded before and one year after treatment. Volume comparisons will be carried out in digital measurement software and data will be obtained and statistically analysed in order to draw the appropriate conclusions.

Official Title
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Volume and Attachment Changes in Autotransplanted Closed Apex Permanent Teeth. Prospective Case Series With One-year Follow-up

Conditions
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Transplantation, Autologous, Autografts, Surgery, Oral

Intervention / Treatment
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* Procedure: Tooth Autotransplantation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients in ASA-I health status Aged between 18 and 80 years, Present a tooth in need of extraction with a mature candidate donor tooth compatible with the recipient bed Acceptance of proposed treatment of dental autotransplantation Exclusion Criteria: Unavailability of a candidate donor tooth Refusal of proposed treatment of dental autotransplantation

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Autotransplantation<br>Patients who receive one tooth autotransplanted. | Procedure: Tooth Autotransplantation<br>* Place another tooth in the place of the newly extracted tooth in the same patient.<br>* Other names: Dental autotransplant;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Soft tissue volume changes | Soft tissue volume changes in the buccal side of the site in mm3 | 2 times measurement: day 0 and 12 months after | 
| Periodontal probing pocket depth | Periodontal probing pocket depth in mm | 12 months after | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Patients satisfaction after treatment | Satisfaction assessed by Numeric Rating Scale (NRS) form 0 to 10, being 0 not satisfied at all and 10 very satisfied. | 12 months after the reception of the treatment |