Experimentation With Screening for Bronchopulmonary Cancer and Primary Cardiovascular Prevention, Early Management of COPD and an Offer Exempted From Smoking Cessation

Study Overview
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Brief Summary
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The study consists of recruiting a target population by sending a letter from the Regional Center for Cancer Screening in Ile de France. In the screening program, a battery of examinations will be carried out at inclusion, one year, 2 years, 3 years, 4 years and 5 years.

Detailed Description
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The patients will be recruited by correspondence by by sending a letter from the Regional Center for Cancer Screening in Ile de France. When the patient has agreed to participate, a screening program will be carried out The screening program includes performing a low-dose chest CT scan (STBD), spirometry, blood sampling (biobank + screening for cardiovascular risk factors) on inclusion, at 1 year and at 2 years. Subsequently, a telephone interview will be scheduled for 3 years to collect medical information, for a total follow-up period of 5 years. At each visit, a structured offer of smoking cessation will be proposed and a collection of the quality of life will be carried out. Each year, a telephone call from participants will be scheduled in order to maximize participation

Official Title
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Bronchopulmonary Cancer Screening Program and Primary Cardiovascular Prevention, Early Management of COPD and Smoking Cessation

Conditions
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the Rate of Participation in Screening for PBC

Intervention / Treatment
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* Other: screening for bronchopulmonary cancer


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Women and men Age: 55 to 74 years old Smokers at more than 20 pack-years weaned for less than 15 years Affiliated to a social security organization Exclusion Criteria: Presence of signs of PBC Subjects with a personal history of PBC of less than 5 years or under treatment Presence of serious comorbidities involving the vital prognosis at 6 months Subjects who have already benefited from a chest CT scan less than one year old. Refusal to participate in the study Absence of exposure to tobacco or insufficient exposure to tobacco or withdrawal > 15 years Patient on long-term oxygen therapy Metal implants (thorax, spine) which can cause a deterioration in the quality of the image of the low dose scanner Subject included in another study protocol

Ages Eligible for Study
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Minimum Age: 55 Years
Maximum Age: 74 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| bronchopulmonary cancer<br>The screening program includes performing a low-dose chest CT scan (STBD), spirometry, blood sampling (biobank + screening for cardiovascular risk factors) on inclusion, at 1 year and at 2 years. Subsequently, a telephone interview will be scheduled for 3 years to collect medical information, for a total follow-up period of 5 years. At each visit, a structured offer of smoking cessation will be proposed and a collection of the quality of life will be carried out. Each year, a telephone call from participants will be scheduled in order to maximize participation. For subjects presenting with anomalies suggestive of PBC on the STBD, a consultation in pneumo-oncology will be planned with management corresponding to routine care. | Other: screening for bronchopulmonary cancer<br>* The screening program includes performing a low-dose chest CT scan (STBD), spirometry, blood sampling (biobank + screening for cardiovascular risk factors) on inclusion, at 1 year and at 2 years. Subsequently, a telephone interview will be scheduled for 3 years to collect medical information, for a total follow-up period of 5 years. At each visit, a structured offer of smoking cessation will be proposed and a collection of the quality of life will be carried out. Each year, a telephone call from participants will be scheduled in order to maximize participation<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rate of population participation in PBC screening |  | Baseline |