The Medicines Advice Service Evaluation

Study Overview
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Brief Summary
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The purpose of this study is to find out whether talking to a pharmacist on the telephone can help to support people taking medicine for a long-term condition.

Detailed Description
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Non-adherence to medication is common and although some interventions have shown promise in improving adherence, the findings are inconsistent. This randomised controlled trial aims to test the effectiveness of a pharmacy-based telephone intervention compared to usual care on medication adherence and health outcomes in patients taking medicines for a long-term condition.

Official Title
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The Medicines Advice Service: A Randomised Controlled Trial of a Pharmacy-based Telephone Intervention to Support Patients Taking Medication for a Long-term Condition

Conditions
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Type 2 Diabetes, Hyperlipidemias

Intervention / Treatment
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* Other: Medicines Advice Service


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients prescribed medication(s) for at least one of the following conditions: type 2 diabetes, hyperlipidemia Exclusion Criteria: Patients living outside of England Patients with no access to a telephone Patients under the age of 18 Patients unable to give written informed consent Patients on drugs for dementia Patients showing signs of dementia or cognitive impairment in conversation Patients with substantial hearing or sight impairment Patients whose medications are ordered by a caregiver/family member Patients with insufficient English to take part in the telephone intervention Patients living with someone already taking part in the study Patients newly prescribed a medication for the conditions listed in the inclusion criteria

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Patient-centred tailored intervention<br>Medicines Advice Service | Other: Medicines Advice Service<br>* The intervention consists of: Telephone consultations with a pharmacist Follow-up tailored written information A medicine reminder chart<br>|
| No Intervention: Control<br>Usual care | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Self-reported medication adherence |  | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prescription refill adherence |  | Baseline, 6 months and 12 months | 
| Self-reported medicine-related problems and concerns | Medicine-related problems and concerns will be assessed in a self-report questionnaire. | Baseline, 3 months and 6 months | 
| Beliefs about Medicines | Beliefs about medicines will be assessed in a self-report questionnaire using the Beliefs About Medicines Questionnaire (BMQ) (Horne et al. 1999). | Baseline, 3 months and 6 months | 
| HbA1c |  | Baseline and 6 months | 
| Serum Cholesterol Levels |  | Baseline and 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Adherence