Combined PENG and LFCN Block for Total Hip Arthroplasty

Study Overview
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Brief Summary
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A clinical trial investigating the effect of a combined locoregional anesthesia technique on the postoperative analgesia outcomes after a total hip arthroplasty. A PENG block will be used in combination with a LFCN block. The results will be compared to a control group that is solely treated with intravenous analgesia. This technique aims to provide improved pain scores after surgery without interference of revalidation.

Official Title
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Combined Pericapsular Nerve Group (PENG) and Lateral Femoral Cutaneous Nerve (LFCN) Block for Total Hip Arthroplasty: A Randomized Controlled Trial

Conditions
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Anesthesia, Conduction, Pain, Postoperative, Arthroplasty, Replacement, Hip

Intervention / Treatment
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* Procedure: PENG + LFCN block
* Drug: Ropivacaine injection


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: adult patients who underwent a primary total hip replacement under general anesthesia Exclusion Criteria: insulin dependent diabetes mellitus chronic pain severe dementia or mental retardation allergy to local anesthetics

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 90 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: prospective randomized controlled trial
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: PENG + LFCN block<br>The participants in this group received a combined regional technique just before surgery: Pericapsular nerve group (PENG) block Lateral femoral cutaneus nerve (LFCN) block | Procedure: PENG + LFCN block<br>* Regional anesthesia technique<br>* Other names: lateral femoral cutaneous nerve block;Drug: Ropivacaine injection<br>* Local anesthetic used for peripheral nerve block.<br>* Other names: ropivacaine 0.375%;|
| No Intervention: No regional anesthesia<br>Control group | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Initial pain score | numeric rating score (NRS) of 0 to 10 | 0 hours postoperative | 
| Pain score after 2h | numeric rating score (NRS) of 0 to 10 | 2 hours postoperative | 
| Pain score after 24h | numeric rating score (NRS) of 0 to 10 | 24 hours postoperative | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Initial motor function | score chart inspired by the Bromage score (NRS) of 0 to 3 | 0 hours postoperative | 
| Motor function after 2h | score chart inspired by the Bromage score (NRS) of 0 to 3 | 2 hours postoperative | 
| Motor function after 24h | score chart inspired by the Bromage score (NRS) of 0 to 3 | 24 hours postoperative | 
| Intraoperative opioids | dose of intravenous opioids in microgram per kilogram bodyweight | intraoperative | 
| Postoperative opioids | dose of intravenous opioids in microgram per kilogram bodyweight | 24 hours postoperative | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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regional anesthesia, postoperative pain, total hip arthroplasty, pericapsular nerve group block