Computer Guided Versus Conventional Augmentation Using Bone Ring

Study Overview
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Brief Summary
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Using bone ring grafts with simultaneous implant placement after three-dimensional augmentation of severely defective bone ridges using computer-guided surgical templates. The study compares accuracy effectiveness by mimics software

Detailed Description
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To study the effectiveness of computer guided surgical stents in ridge augmentation with implant insertion compared with free hand augmentation -Population/Intervention/Comparator/Outcome (PICO)- Population (P): patients with massive bone resorption horizontally and vertically, severe bone loss around teeth, periodontal disease or traumatic extraction in partially edentulous maxillary anterior region requiring implant insertion. Intervention (I): simultaneous implant placement with ridge augmentation using computer guided surgical templates with PRF. Comparator (C): Free hand simultaneous implant placement with ridge augmentation. Outcome (O): Patient esthetic satisfaction - Augmentation and implant insertion accuracy

Official Title
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Evaluation of Computer-Guided Versus Conventional Simultaneous Implant Placement With Ridge Augmentation Using an Autogenous Bone Ring Graft With PRF on Patient's Esthetic Satisfaction

Conditions
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Bone Resorption

Intervention / Treatment
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* Procedure: Computer Guided Stent Augmentation
* Procedure: Free Hand Augmentation
* Drug: Platelet-rich fibrin (PRF)
* Device: implant


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients with insufficient alveolar ridge or severe alveolar bone resorption horizontally and vertically in partially edentulous maxillary anterior region. Medically free patients in order to be a confounding factor on the final results. Highly motivated patients. Good oral hygiene. Patients physically able to tolerate surgical and restorative procedures. Exclusion Criteria: Young patients (incomplete bone growth). Patients with any systemic disease that could affect bone healing. Patients allergic to local anaesthetic agent. Pregnant or lactating females. Presence of any pathosis in the area. history of oral radiotherapy. history of prolonged steroid use. Psychological disorders.

Ages Eligible for Study
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Minimum Age: 21 Years
Maximum Age: 55 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Computer Guided Stent Augmentation<br>Patients with defective maxillary anterior alveolar ridges requiring implant insertion will have simultaneous implant placement with ridge augmentation using autogenous bone ring graft covering them with Platelet-rich fibrin (PRF) using computer guided stent. | Procedure: Computer Guided Stent Augmentation<br>* Defective alveolar ridge is to be replaced by simultaneous implant placement with ring graft augmentation (Trephine Drill to obtain the ring graft autogenous bone) using computer guided stent and covered with Platelet-rich fibrin (PRF), by using venous blood from the patient, a centrifuge will be used to obtain the top layer after centrifuging blood at 3000 Revolution Per Minute (RPM) for 10 minutes.<br>* Other names: Autograft;Drug: Platelet-rich fibrin (PRF)<br> <br> Device: implant<br> <br> |
| Active Comparator: Free Hand Augmentation<br>Patients with defective maxillary anterior alveolar ridges requiring implant insertion will have simultaneous implant placement with ridge augmentation using Free hand simultaneous implant placement with ridge augmentation and covering them with Platelet-rich fibrin (PRF). | Procedure: Free Hand Augmentation<br>* Defective alveolar ridge is to be replaced by Free Hand simultaneous implant placement with ring graft augmentation (Trephine Drill to obtain the ring graft autogenous bone) and covered with Platelet-rich fibrin (PRF), by using venous blood from the patient, a centrifuge will be used to obtain the top layer after centrifuging blood at 3000 RPM for 10 minutes.<br>* Other names: Autograft;Drug: Platelet-rich fibrin (PRF)<br> <br> Device: implant<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Patient Satisfaction regarding esthetic results. | outcome will be measured using questionnaire | 5 month | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Accuracy of computer guided surgical templates in comparison with 3D virtual planning. | Comparing the results on the patient with the design made by the surgical software. | immediately after procedure |