Tailored Internet-administrated Treatment of Panic Symptoms - A Randomised Controlled Trial

Study Overview
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Brief Summary
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The purpose of this study is to determine whether tailored internet-administrated CBT is a feasible approach in the treatment of panic symptoms and comorbid anxiety and depressive symptoms.

Official Title
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Tailored Internet-administrated Treatment of Panic Symptoms - A Randomised Controlled Trial

Conditions
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Anxiety Disorders, Depression

Intervention / Treatment
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* Behavioral: Tailored Internet-administrated CBT-Treatment
* Behavioral: Waitlist


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Be between the ages of 18-30 years old or 31-46 years old Have reoccurring panic attacks Exclusion Criteria: Suicide prone Alcohol addiction PTSD OCD Ongoing psychological treatment

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Tailored Internet-delivered CBT<br>Behavioral: Tailored Internet-delivered CBT | Behavioral: Tailored Internet-administrated CBT-Treatment<br>* This intervention contains 6-8 text-based self-help modules in which 4 modules are fixed (the first three and the last) and the rest are prescribed following the diagnostic telephone interview. These modules contain material on panic disorder, social phobia, stress management, assertiveness training, concentration, relaxation among other things.<br>|
| Active Comparator: Waitlist<br>Waitlist. | Behavioral: Waitlist<br>* Passive waitlist during 8-10 weeks.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Panic Disorder Severity Scale (PDSS) | Change from baseline in panic symptoms two weeks post treatment, at six months and at 12 months post treatment. | Two weeks pre treatment, two weeks post treatment, six months and 12 months post treatment | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Clinical Outcome in Routine Evaluation - Outcome Measure (CORE-OM) | Change from baseline in anxiety and depressive symptoms two weeks post treatment, at six months and at 12 months post treatment. | Two weeks pre treatment, two weeks post treatment, six months and 12 months post treatment | 
| Beck Anxiety Inventory (BAI) | Change from baseline in anxiety symptoms two weeks post treatment, at six months and at 12 months post treatment. | Two weeks pre treatment, two weeks post treatment, six months and 12 months post treatment | 
| Montgomery Åsberg Depression Rating Scale-Self Rated (MADRS-S) | Change from baseline in depressive symptoms two weeks post treatment, at six months and at 12 months post treatment. | Two weeks pre treatment, two weeks post treatment, six months and 12 months post treatment | 
| Quality of Life Inventory (QOLI) | Change from baseline in quality of life statements two weeks post treatment, at six months and at 12 months post treatment. | Two weeks pre treatment, two weeks post treatment, six months and 12 months post treatment |