A Naturalistic Study of Adolescents and Young Adults in Treatment for Opioid Dependence

Study Overview
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Brief Summary
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Many buprenorphine treatment programs do not have services dedicated to adolescents and young adults. As a precursor to developing and evaluating an adolescent and young adult buprenorphine treatment program at APT Foundation Inc, we propose to conduct a 1 year prospective study of 16 to 25 year old treatment-seeking individuals enrolled in the APT Adolescent and Young Adult Suboxone Program

Detailed Description
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Participants will consent to in-person assessments and monthly chart reviews. We anticipate that the results from this study will inform the development of future services targeted towards adolescents and young adults with opioid dependence.

Official Title
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A Naturalistic Study of Adolescents and Young Adults in Treatment for Opioid Dependence

Conditions
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Opioid Dependence

Intervention / Treatment
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* Other: Naturalistic Prospective Cohort


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Ages 16 through 25 at time of induction Meet criteria for enrollment in the APT Adolescent and Young Adult Suboxone Program (Opioid Dependence per DSM-V criteria; no contraindications to buprenorphine (concomitant benzodiazepine, alcohol use, sedative use), Stable enough to participate in outpatient care/intensive outpatient care for at least 12 weeks; Can commit to at least 12 weeks of treatment through the APT Adolescent and Young Adult Suboxone Program Are willing to provide locator information for follow-up. Are fluent in English and have a 6th grader or higher reading level Exclusion Criteria: Have an untreated bipolar or schizophrenic disorder, or active suicidal ideation Are physically dependent on alcohol, benzodiazepines, or other sedatives. Are in custody of the Department of Children and Families

Ages Eligible for Study
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Minimum Age: 16 Years
Maximum Age: 25 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Naturalistic Prospective Cohort|Follow subjects through 1 year of naturalistic buprenorphine treatment|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Opioid Use Patterns | To describe the progression of opioid use among adolescents and young adults participating in buprenorphine treatment, the subjects will fill out time line follow back surveys to describe opioid use patterns. | baseline | 
| Opioid Use Patterns | To describe the progression of opioid use among adolescents and young adults participating in buprenorphine treatment, the subjects will fill out time line follow back surveys to describe opioid use patterns. | 4 weeks | 
| Opioid Use Patterns | To describe the progression of opioid use among adolescents and young adults participating in buprenorphine treatment, the subjects will fill out time line follow back surveys to describe opioid use patterns. | 8 weeks | 
| Opioid Use Patterns | To describe the progression of opioid use among adolescents and young adults participating in buprenorphine treatment, the subjects will fill out time line follow back surveys to describe opioid use patterns. | 12 weeks | 
| Opioid Use Patterns | To describe the progression of opioid use among adolescents and young adults participating in buprenorphine treatment, the subjects will fill out time line follow back surveys to describe opioid use patterns. | 24 weeks | 
| Opioid Use Patterns | To describe the progression of opioid use among adolescents and young adults participating in buprenorphine treatment, the subjects will fill out time line follow back surveys to describe opioid use patterns. | 52 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Opioid Use Patterns | Urine drug screen results (opioids (and type if noted) benzodiazepines, marijuana, , cocaine, amphetamines) collected monthly from medical charts. | One year | 
| Cigarette Use Patterns | To describe the progression of cigarette use among adolescents and young adults participating in buprenorphine treatment, the subjects will fill out time line follow back surveys to describe cigarette use patterns. | One year |