Evident, Occult and no Demonstrated USI and UDS Findings in Women With ≥Stage II Cystocele

Study Overview
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Brief Summary
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Prevalence rates of urodynamic urinary incontinence (USI) subtypes and their related clinical and urodynamic findings in women with ≥ pelvic organ prolapse quantification stage II cystocele are important for clinical consultation, especially for occult USI. Misdiagnosis of occult USI before cystocele repair might lead to occurrence of de novo stress urinary incontinence after cystocele repair. Thus, the aim of this study was to elucidate the above findings and between-group associations.

Detailed Description
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Between November 2011 and January 2017, medical records of all women with ≥stage II cystocele who underwent urodynamic studies in a medical center were reviewed. ANOVA test and post-hoc testing with bonferroni's correction were used for statistical analysis. USI is noted during filling cystometry and is defined as the involuntary leakage of urine during increased abdominal pressure, in the absence of a detrusor contraction. The recruited patients with cystocele were classified into three groups (i.e.,evident USI, occult USI and no demonstrated USI) according to pad weight results before and after prolapse reduction.

Official Title
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Prevalence Rates of Evident, Occult and no Demonstrated Urodynamic Stress Incontinence and Their Clinical and Urodynamic Findings in Women With ≥Stage II Cystocele

Conditions
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Urodynamic Stress Incontinence in Severe Cystocele Women

Intervention / Treatment
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* Diagnostic Test: Urodynamic study


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age >20y/o Cystocele > stage II Complete urodynamic study Exclusion Criteria: Pregnancy Urinary tract infection Previous pelvic reconstruction surgery

Ages Eligible for Study
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Minimum Age: 20 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Evident urodynamic stress incontinence(USI)<br>Between November 2011 and January 2017, medical records of all women with ≥stage II cystocele who underwent urodynamic studies in a medical center were reviewed. USI is noted during filling cystometry and is defined as the involuntary leakage of urine during increased abdominal pressure, in the absence of a detrusor contraction. | Diagnostic Test: Urodynamic study<br>* Urodynamic study: including uroflowmetry, filling cystometry, voiding cystometry, and urethral pressure profile<br>|
| Occult USI<br>Between November 2011 and January 2017, medical records of all women with ≥stage II cystocele who underwent urodynamic studies in a medical center were reviewed. USI is noted during filling cystometry and is defined as the involuntary leakage of urine during increased abdominal pressure, in the absence of a detrusor contraction after prolapse reduction by vaginal gauze. | Diagnostic Test: Urodynamic study<br>* Urodynamic study: including uroflowmetry, filling cystometry, voiding cystometry, and urethral pressure profile<br>|
| ND USI<br>Between November 2011 and January 2017, medical records of all women with ≥stage II cystocele who underwent urodynamic studies in a medical center were reviewed. No USI was noted in this group. | Diagnostic Test: Urodynamic study<br>* Urodynamic study: including uroflowmetry, filling cystometry, voiding cystometry, and urethral pressure profile<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evident USI | USI note before reduction of prolapse | Between November 2011 and January 2017 | 
| Occult USI | USI note after reduction of prolapse | Between November 2011 and January 2017 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Cystocele, Urodynamic stress incontinence, Pad test, Urodynamic study