The Effect of HIIT in Handling Obesity in Children

Study Overview
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Brief Summary
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In this study the investigators wish to investigate whether a short duration High-intensity Interval Training(HIT) is superior to a moderate activity training modus with regards to improving weight-loss, Blood pressure and sleep quality in severely obese children and adolescents also receiving a multidisciplinary treatment regime.

Detailed Description
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Prevalence of overweight and obesity among children and adolescents are rapidly rising worldwide. Despite the alarming situation, great confusion of how to tackle obesity persists for two main reasons: the condition is much more complex than initially thought, and many aspects regarding pathophysiology remain unrevealed, leading to an insufficient understanding of the disorder. Childhood obesity is, strongly associated with numerous disorders e.g. hypertension, insuline resistance, sleep apnea, depression and many more. High intensity Interval Training has proven beneficial in treating obesity and comorbidities in adults. The investigators wish to investigate whether twelve weeks of High-intensity Interval Training(HIT) twice a week is superior to a moderate activity training modus for same period of time with regards to improving weight loss, blood pressure and sleep quality, in severely obese children and adolescents also receiving a multidisciplinary treatment regime. Participants are severely obese children and adolescents referred to the outpatient Clinic for treatment of obesity. Participants are randomizid to either moderate training or HIIT. Antropometric measures, blood pressure and sleep quality as measured by sensewear armbands, are done at baseline, after the twelve weeks of training and again one year after inclusion. Participants are monitored with pulse monitors during training sessions to register if training goals are obtained.

Official Title
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The Effect of High Intensity Interval Training in Handling Obesity in Children and Adolescents. A Randomized Controlled Trial.

Conditions
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High Intensity Interval Training, Child Obesity

Intervention / Treatment
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* Behavioral: HIIT
* Behavioral: Moderate training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Iso-BMI > 30 according to the IOTF iso-BMI cut-off points Age 8-18 years of age Exclusion Criteria: Weight below iso-BMI 30, according to the IOTF iso-BMI cut-off points Mental illness in the child or the parents that complicates attendance at activities. Physical limitations or illness that prevent the child from performing exercise If participant is not able to perform all 12 weeks of exercise for other reasons.

Ages Eligible for Study
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Minimum Age: 8 Years
Maximum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Randomized Controlled trial
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: High Intensity Interval Training<br>Twelve weeks of High Intensity Interval Training, twice a week, in combination with multidisciplinary treatment at outpatient obesity clinic. | Behavioral: HIIT<br>* High Intensity Interval Training for twelve weeks<br>|
| Active Comparator: Moderate training<br>Twelve weeks of Moderate Training, twice a week, in combination with multidisciplinary treatment at outpatient obesity clinic. | Behavioral: Moderate training<br>* Moderate training for twelve weeks<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Weight reduction | In Kg | Twelve months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Blood pressure | 24-hour blood pressure Measurements done by spacelaps 90217A | At baseline, after twelve weeks training and after twelve months | 
| Sleep Quality | Measured by sensewear armbands which is worn for a week at a time | At baseline, after twelve weeks training and after twelve months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Child Obesity, Adolescents, High Intensity Interval Training, Moderate training