Treatment of Sudden Deafness With Prednisone+Hyperbaric Oxygen and Prednisone+Somatosensory Stimulation

Study Overview
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Brief Summary
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To study the effective treatment of sudden deafness by giving prednisone, hyperbaric oxygen and somatosensory stimulation to sudden deafness patients.

Detailed Description
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60 cases of sudden deafness within 2 months of 14-80 years old were randomly divided into two groups. They underwent hearing tests, magnetic resonance imaging of the head, and routine hospital admissions. One group was given prednisone for 1 mg / kg body weight × 7 days + somatosensory stimulation × 30 days, the other group was given prednisone for 1 mg / kg body weight × 7 days + hyperbaric oxygen × 15 days, and repeated electrical audiometry every week. One month and three months after the experiment, repeated audiometry.

Official Title
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Prospective Study of Sudden Deafness

Conditions
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Hearing Loss, Sudden, Prednisone Acetate, Hyperbaric Oxygen, Somatic Stimulus

Intervention / Treatment
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* Combination Product: Drugs and Stimulation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Sudden deafness History within 2 months Age 14-80 Exclusion Criteria: Neurological diseases (such as brain tumors) Patients with mental / mental illness undergoing treatment Pregnant women and patients with other untreatable diseases Finding the cause of sensorineural deafness Patients Not Suitable for Hyperbaric Oxygen A patient with dermatosis

Ages Eligible for Study
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Minimum Age: 14 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Prednisone acetate + somatosensory stimulation<br>Prednisone acetate 1 mg/kg body weight * 7 days and somatosensory stimulation 30 days were given to sudden deafness patients. | Combination Product: Drugs and Stimulation<br>* 60 cases of sudden deafness were inquired about their medical history and examined by hearing and cranial magnetic resonance. They were randomly divided into two groups and given different treatments. The hearing test was repeated every 7 days. One month and three months after the treatment, the hearing examination was reexamined.<br>|
| Experimental: Prednisone acetate + hyperbaric oxygen<br>Prednisone acetate 1mg / kg body weight * 7 days and hyperbaric oxygen 15 days were given to sudden deafness patients. | Combination Product: Drugs and Stimulation<br>* 60 cases of sudden deafness were inquired about their medical history and examined by hearing and cranial magnetic resonance. They were randomly divided into two groups and given different treatments. The hearing test was repeated every 7 days. One month and three months after the treatment, the hearing examination was reexamined.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Audiometry | Evaluate the patient's hearing to determine whether it has improved. | Three months from the patient's selection to the end of treatment | 
| Cranial magnetic resonance imaging | Judging whether the patient's inner ear has pathological changes or not | When patients are enrolled | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Hearing Loss, Sudden, Prednisone acetate, Hyperbaric oxygen, Somatic stimulus