Effect of Social Media Support and Financial Incentives on PrEP Adherence

Study Overview
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Brief Summary
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The purpose of this study is to determine if social media support and financial incentives improve adherence to Truvada as PrEP in African American, Latino and Asian MSM aged 18 to 24 living in the Washington, DC area who are at high risk for HIV acquisition.

Official Title
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The Effect of Social Media Support and Financial Incentives on Adherence to HIV Pre-exposure Prophylaxis in Young MSM of Color in Washington, DC

Conditions
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Pre-Exposure Prophylaxis

Intervention / Treatment
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* Behavioral: Financial Incentive
* Behavioral: Social Media Group


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Male assigned at birth (regardless of current gender identity) Age 18-24 Black/African American, Latino or Asian HIV negative History of unprotected anal sex with a man in the last 6 months Living within the DC metropolitan statistical area and anticipate remaining within the DC area for the next 6 months Not enrolled in any other HIV prevention trial Interested in taking PrEP Not a current PrEP user and have not taken PrEP in the last 30 days Able to provide informed consent Exclusion Criteria: Female sex at birth Age younger than 18 or older than 24 Caucasian HIV positive Actively taking PrEP or having taken PrEP within 30 days of enrollment Chronic hepatitis B infection Known renal insufficiency On probation or parole Any other conditions that the Principal Investigator may consider a contraindication to enrolling in the study

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 24 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Financial Incentive<br>Provided financial incentive at 3-month and 6-month follow-up visits | Behavioral: Financial Incentive<br>* Participants will receive a $50 gift card at 3- and 6- month follow-up visits.<br>|
| Experimental: Social Media Group<br>Provided social media support through a facebook group for 6 months | Behavioral: Social Media Group<br>* Participants will be invited to a study Facebook group which will have links to PrEP information and provide a forum for participants to ask questions and communicate their experience with PrEP<br>|
| No Intervention: Control<br>No intervention | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Adherence To Truvada | Level of Truvada drug levels inside red blood cells (performed by dried blood spots) | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| New Cases of HIV | Number of reactive HIV rapid and 4th generation tests | 6 months | 
| Incidence of STIs | Positive RPR, oropharyngeal/rectal/penile chlamydia and gonorrhea during study | 6 months |