Exercise Program of Breast Cancer Patients Undergoing Chemotherapy With or Without Radiation

Study Overview
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Brief Summary
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The purpose of this study is to study if a patients follows an exercise program specifically designed for them during the time of their treatment after surgery. Their ability to follow the program and its influence on their weight maintenance and early post-operative lymphedema rates will also be studied. Lymphedema is a condition in which excess fluid collects in tissue and causes swelling of the arm(s).

Official Title
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A Feasibility Study of the Effects of a Directed Exercise Program of Breast Cancer Patients Undergoing Chemotherapy With or Without Radiation

Conditions
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Breast Cancer

Intervention / Treatment
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* Other: standardized regimen of exercises, including a warm-up period, ROM arm exercises, and strength training exercises.


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients will be eligible if they have any of the following surgical procedures performed by an attending on the Breast Service: SLNB alone Axillary lymph node dissection (ALND) alone Total Mastectomy TM (+/- reconstruction) with SLNB or ALND Breast conserving therapy (BCT) with SLNB or ALND Age > 18 years Planned to undergo adjuvant post-operative chemotherapy with or without radiation at MSKCC and have not yet started chemotherapy Exclusion Criteria: Undergoing TM or BCT without SLNB Having had prior breast cancer treated with surgery Unable to participate in a exercise program related to other medical problems More than 8 weeks post surgery. Having a concurrent cancer in addition to breast cancer Who have had any type of chemotherapy in the past two years

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| breast pts who have undergone surgery<br>This will be a feasibility study designed to evaluate the compliance of an at-home, directed exercise program and its influence on physical measures during post-operative adjuvant chemotherapy and radiation (if applicable). | Other: standardized regimen of exercises, including a warm-up period, ROM arm exercises, and strength training exercises.<br>* Module I is a group of arm movements. It consists of stretching exercises coordinated with breathing exercises to restore their physical mobility, range of motion and flexibility of shoulders. Module I is to be performed daily. In Module II the exercises are a series of copyrighted, sequential movements designed to put the body in proper alignment. It is a special series of muscle movements to help establish better body alignment, as well as increased strength and flexibility of one's arms, legs, and spine, each exercise is 4 repetitions. Module III is the walking and the resistance weight training program. The walking program is whole body exercise, multi-joint, weight-bearing, low impact and for beginners to advanced.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To evaluate compliance with and demonstrate the feasibility of an at-home, directed exercise program during adjuvant chemotherapy and radiation (if applicable). |  | 2 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To describe how this exercise program affects weight maintenance and percent body fat during adjuvant chemotherapy and radiation. |  | 2 years | 
| To describe how this exercise program affects early post-operative lymphedema rates, monitoring the strength training specifics -including the number of repetitions and sets of each exercise, frequency, and order of exercises. |  | 2 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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exercise, lymphedema, post-operative chemotherapy, post-operative radiation, 10-062