Short Term Results of Tele-Rehabilitation

Study Overview
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Brief Summary
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Most people who have coronavirus disease (COVID-19) recover completely without any sequelae. However, some patients continue to experience symptoms of COVID-19 even though their tests turn negative. This clinical spectrum that occurs after acute infection is called the post-COVID syndrome (PCS). Dyspnea, pain, decreased exercise capacity, limitations in activities of daily living, poor sleep quality, anxiety and depression are common symptoms in PCS. The aim of our study is to examine the effect of tele-rehabilitation-based exercise program on dyspnea, pain, functional capacity, sleep quality, anxiety and depression in individuals with PCS.

Official Title
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Short Term Outcomes of Tele-Rehabilitation in Patients With Post-Covid Syndrome

Conditions
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COVID-19, Dyspnea

Intervention / Treatment
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* Other: Tele-rehabillitation
* Other: Prescribed Exercise Program


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Being between the ages of 18-75, Being in stable medical condition, conscious and cooperative, Having had COVID and continuing symptoms Volunteering to participate in the study, Own a device that can be connected online independently or with support from family members. Exclusion Criteria: SpO2 < 92%, Hypotension (Systolic Blood Pressure < 90 mmHg or Diastolic Blood Pressure < 60mmHg) Having chronic respiratory disease (COPD, Asthma, etc.) Having a stroke or neurodegenerative disease. Not being willing to participate in the study

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Intervention<br>Participants will receive a supervised tele-rehabilitation program 2 days a week for 6 weeks. | Other: Tele-rehabillitation<br>* Tele-rehabilitation program will be performed by physiotherapist two times a week for six consecutive weeks. Program including the following exercises: Breathing exercises Aerobic exercises Flexibility Strengthening exercises<br>|
| Other: Control<br>Participants will receive the same rehabilitation program as prescribed. | Other: Prescribed Exercise Program<br>* The prescribed exercise program will be performed two times a week for six consecutive weeks. Program including the following exercises: Breathing exercises Aerobic exercises Flexibility Strengthening exercises<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change from the baseline to the 6th week in mMRC (Modified Medical Research Council) Dyspnoea Scale | The mMRC Dyspnoea Scale is used to assess the degree of baseline functional disability due to dyspnoea | Baseline and 6th week | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change from the baseline to the 6th week in NPRS | The Numerical Rating Scale (NPRS-11) is an 11-point scale for self-report of pain. It is the most commonly used unidimensional pain scale. The respondent selects a whole number (integers 0-10) that best reflects the intensity (or other quality if requested of his/her pain. | Baseline and 6th week | 
| Change from the baseline to the 6th week in the 5 times sit to stand test (5XSST) | The 5XSST scoring is based on the amount of time (to the nearest decimal in seconds) a patient is able to transfer from a seated to a standing position and back to sitting five times. The equipment need in performing 5XSST test includes: Stopwatch and standard height chair with straight back. | Baseline and 6th week | 
| Change from the baseline to the 6th week in the Hospital Anxiety and Depression Scale | The Hospital Anxiety and Depression Scale (HADS) was devised to measure anxiety and depression in a general medical population of patients. The questionnaire comprises seven questions for anxiety and seven questions for depression, and takes 2-5min to complete. Although the anxiety and depression questions are interspersed within the questionnaire, it is vital that these are scored separately. | Baseline and 6th week | 
| Change from the baseline to the 6th week in the The Pittsburgh Sleep Quality Index | The Pittsburgh Sleep Quality Index (PSQI) is a measure of self-reported sleep quality and sleep disturbance. Scoring Using a four-point, Likert-type scale, respondents indicate how frequently they exhibit certain sleep behaviors (0 = few, 1 = some- times, 2 = often, and 3 = almost always). The PSQI takes about 10 minutes to complete and it doesn't involve any procedures or interventions. | Baseline and 6th week | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Tele-rehabilitation, COVID-19