Clinical Comparison of Different Adhesives in NCCLs

Study Overview
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Brief Summary
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The aim of this randomized, controlled, prospective clinical trial is to evaluate the performances of a universal adhesive in three different application modes, a self-etch adhesive and an etch&rinse adhesive in restoration of non-caries cervical lesions. Thirty-four patients will receive restorations. Lesions will be divided into 5 groups according to adhesive systems and application modes: CU-SE: Clearfil Universal Bond Quick in self-etch mode, CU-SLE: Clearfil Universal Bond Quick in selective etch mode, CU-ER: Clearfil Universal Bond Quick in etch&rinse mode, CSE: Clearfil SE Bond, TB: Tetric N-Bond. Restorations (Tetric N-Ceram composite) will be scored with regard to retention, marginal discoloration, marginal adaptation, recurrent caries and post operative sensitivity using modified USPHS criteria after 48 months. Two examiners who is not involved in the placement of restorations will conduct the evaluations. Descriptive statistics will be performed using Chi-square tests.

Official Title
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Clinical Comparison of Different Adhesives in NCCLs

Conditions
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Tooth Wear

Intervention / Treatment
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* Device: Clearfil Universal Bond Quick
* Device: Clearfil Universal Bond Quick
* Device: Clearfil Universal Bond Quick
* Device: Clearfil SE Bond
* Device: Tetric N-Bond


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: being 18 years or older, having no medical or behavioral problems preventing then from attending review visits, having at least 5 tooth with NCCLs having antagonist teeth Exclusion Criteria: poor gingival health, uncontrolled, rampant caries, bruxism, removable partial dentures, xerostomia

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Clearfil Universal Bond Quick, self-etch mode (CU-SE)<br> | Device: Clearfil Universal Bond Quick<br>* Adhesive systems<br>|
| Experimental: Clearfil Universal Bond Quick, selective etch mode (CU-SLE)<br> | Device: Clearfil Universal Bond Quick<br>* Adhesive systems<br>|
| Experimental: Clearfil Universal Bond Quick, etch&rinse mode (CU-ER)<br> | Device: Clearfil Universal Bond Quick<br>* Adhesive systems<br>|
| Experimental: Clearfil SE Bond (CSE)<br> | Device: Clearfil SE Bond<br>* Adhesive systems<br>|
| Experimental: Tetric N-Bond (TB)<br> | Device: Tetric N-Bond<br>* Adhesive systems<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Clinical performances of different adhesives | Two year examinations according to USPHS criteria | two years |