Hysteroscopic Bubble Suction Test and Tubal Peristalsis (Darwish Test) in Hydrosalpnix

Study Overview
=================
Brief Summary
-----------------
Tubal patency testing is essential for infertility evaluation. Standard tests are hysterosalpingography and laparoscopic perchromation test. In 2016, a hysteroscopic bubble suction test was described in apparently normal tubes. However, the efficacy of bubble suction test in abnormal tubes like hydrosalpnix has not been studied.

Detailed Description
-----------------
Nowadays, hysteroscopy is extensively used for fertility assessment. In a previous study, it is recommended to add hysteroscopy to the routine infertility work-up to achieve a better assessment of infertility cases. In 2016, hysteroscopy as a predictor test of tubal patency and tubal peristalsis was introduced. It is concluded that hysteroscopic bubble suction test is a good initial screening test for tubal patency nearly comparable to HSG and DL. It should be attempted in every case of OH prior to referral for more invasive HSG or laparoscopic chromopertubation test. Thereafter, some authors tried the same idea of bubble suction test and were over-enthusiastic with this test and considered it superior to hysterosalpingography (HSG) in detection of tubal patency in infertile women. They wrongly described HSG as a historic tool despite being recommended as a basic infertility test by many organizations. Some authors criticized the results of these studies and underestimated their clinical implication. One of the objections were lack of differentiation between normal tubes and damaged or narrowed but still patent tubes. Aim of the work: To test whether bubble suction test and osteal peristalsis are preserved or lost in cases with hydrosalpnix. Design: A prospective double blinded randomized controlled trial.

Official Title
-----------------
Hysteroscopic Bubble Suction Test and Tubal Peristalsis (Darwish Test) in Hydrosalpnix

Conditions
-----------------
Tubal Patency

Intervention / Treatment
-----------------
* Diagnostic Test: Bubble suction test and tubal peristalsis


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Infertility patients scheduled for combined laparoscopy and hysteroscopy Exclusion Criteria: No HSG

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 40 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| bubble suction test and peristalsis in hydrosalpnix<br>. Group A: Women with unilateral or bilateral blockage of the distal end of the fallopian tubes with tubal distension. | Diagnostic Test: Bubble suction test and tubal peristalsis<br>* Efficacy of this test in cases of hydrosalpnix (group A) and normal tubes (group B)<br>|
| bubble suction test and peristalsis in normal tubes<br>Group B: Women with normal appearance of the fallopian tubes by HSG. | Diagnostic Test: Bubble suction test and tubal peristalsis<br>* Efficacy of this test in cases of hydrosalpnix (group A) and normal tubes (group B)<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| percentage of positive tests in both pathologic and healthy tubes | Bubble suction test+ tubal peristalsis | 6 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
laparoscopy, hysteroscopy,, tubal patency,, bubble test,, peristalsis