Study of Disrupted Sleep in Somali Americans

Study Overview
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Brief Summary
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The aims of this study are to determine the types and severity of previously undiagnosed sleep deficiencies in otherwise healthy Somali Americans, apply a research framework to define psychosocial, behavioral, environmental, and biological mechanisms mediating sleep deficiencies in Somali Americans, and examine the relationship between sleep deficiencies and increased blood pressure in Somali Americans.

Official Title
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Disrupted Sleep in Somali Americans - Implications for Hypertension Risk

Conditions
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Hypertension, Sleep Disorder, Healthy

Intervention / Treatment
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* Diagnostic Test: 24 hour blood pressure (BP) monitoring
* Diagnostic Test: Polysomnography


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Subjects diagnosed with no known history of hypertension, diabetes, or sleep disorders. Self-identify as Somali. Adult males and females who are older than 18 years of age. Exclusion Criteria: Anyone under 18 years or over 70 years. Positive pregnancy.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Healthy Somali Americans<br>Somali Americans with no known history of hypertension, diabetes, or sleep disorders will have a 24 hour blood pressure monitoring and polysomnography. | Diagnostic Test: 24 hour blood pressure (BP) monitoring<br>* 24-hour ambulatory BP measuring device and blood pressures will be measured every 20 minutes to half hour<br>Diagnostic Test: Polysomnography<br>* Measurements will include electroencephalogram, electromyogram, electrooculogram, electrocardiogram, breathing patterns of chest and abdomen, nasal and oral airflow and oxygen saturation. Sleep stages and apneas will be scored in accordance with validated American Academy of Sleep Medicine standards.<br>* Other names: Sleep Study;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Undiagnosed sleep deficiency-short sleep | Number of subjects to have short sleep (<6 hours) as measured by the sleep study | 1 night sleep study, approximately 8-9 hours | 
| Undiagnosed sleep deficiency-insomnia | Number of subjects to have insomnia as measured by the sleep study | 1 night sleep study, approximately 8-9 hours | 
| Undiagnosed sleep deficiency-obstructive sleep apnea (OSA) | Number of subjects to have OSA as measured by the sleep study | 1 night sleep study, approximately 8-9 hours | 
| Disrupted sleep | Number of subjects to have disrupted sleep as measured by the sleep study | 1 night sleep study, approximately 8-9 hours | 
| Blood pressure (BP) during wakefulness | Average BP as measured by 24 hour BP monitoring, reported in mmHg | Day 2 | 
| Blood pressure (BP) during sleep | Average BP as measured by 24 hour BP monitoring, reported in mmHg | Day 2 |