Conventional Home Exercise Programs Versus Electronic Home Exercise Versus Artificial Intelligence Virtual Therapy for Anterior Knee Pain

Study Overview
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Brief Summary
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This is a clinical research trial to evaluate the efficacy of delivering exercise therapy for knee pain via the Internet utilizing an algorithm designed to adjust a home exercise program based on user input. The investigators hypothesize that exercise therapy can be delivered safely and effectively with increased participant satisfaction compared to the current standard.

Official Title
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Conventional Home Exercise Programs Versus Electronic Home Exercise Versus Artificial Intelligence Virtual Therapy for Anterior Knee Pain: a Prospective Randomized Comparative Trial.

Conditions
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Patellofemoral Pain Syndrome

Intervention / Treatment
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* Other: Algorithm based Exercise Videos
* Other: PDF Exercise Sheets
* Other: Limited Exercise Videos


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 18-64 with anterior knee pain Have computer access Cleared for exercise by a medical professional, if not possible or a medical professional on the study team over the phone and the PAR-Q (Physical Activity Readiness Questionnaire) Have consented to participate in the trial Exclusion Criteria: Age < 18 or > 64 Screened as unsafe for exercise by a medical professional or the, study team and/ or Screened out by the PAR-Q Does not consent to the trial

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 64 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: PDF exercise sheets<br>Participants in this arm will receive a PDF sheet of 6 exercises that are commonly administered for the treatment of anterior knee pain. They will be asked to perform the exercises three times a week for 6 weeks. A questionnaire will be administered at the three, six and twelve week mark to evaluate efficacy, compliance and safety. | Other: PDF Exercise Sheets<br>* A sheet of six exercises with descriptions on how to perform them properly<br>|
| Active Comparator: Limited Exercise Videos<br>Participants in this arm will receive the same six exercises as provided in the PDF sheet in arm 1 in a video format. They will be asked to perform the exercises three times per week for 6 weeks. A questionnaire will be administered at the three, six and twelve week mark to evaluate efficacy, compliance and safety. | Other: Limited Exercise Videos<br>* Video of 6 exercises that provide instruction on how to perform the exercises<br>|
| Experimental: Algorithm based Exercise Videos<br>Participants in this arm will be provided a 6 week regimen of exercise videos for their anterior knee pain. Following each exercise session, the participant will be asked for their input concerning each exercise. The algorithm will adjust the exercise regimen for the next session based on the participants input. A questionnaire will be administered at the three, six and twelve week mark to evaluate efficacy, compliance and safety. | Other: Algorithm based Exercise Videos<br>* The algorithm will adjust the exercises in each session based upon the participant's feedback.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The 3 and 6 week survey data evaluating efficacy of the algorithm | Each participant will be asked at the 3, 6 and 12 week mark to fill out a survey questionnaire that evaluates their knee pain to determine if their knee pain has improved. | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Participant compliance | We will ask the participant at the 3, 6 and 12 week mark questions concerning whether they enjoyed the video exercises and whether they would do them again. | 6 months | 
| Safety | The screening questionnaires will be evaluated for their safety and efficacy. This will be evaluated by having followup at the 3, 6 and 12 week marks and asking if the participant had any adverse event either via phone calls or survey questionnaire. | 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Knee pain, Anterior knee pain, Patellofemoral, Patellofemoral syndrome, Runners knee