Smart-phone Application to Promote Medication Adherence in Adolescents and Young Adults (AYA) With Cancer

Study Overview
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Brief Summary
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To explore use of a smart-phone medication reminder application to promote adherence to oral medications by AYA with cancer.

Detailed Description
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Non-adherence to oral medications is a prevalent problem in adolescents and young adults (AYA) with cancer that may impact both survival and quality of life while on treatment. The purpose of this study is to explore use of a smart-phone medication reminder application to promote adherence to oral medications by AYA with cancer. The study's primary aim is to explore the feasibility and acceptability of using a smart-phone medication reminder application to promote adherence to oral medications by AYA with cancer as well as to characterize application use. Secondary aims include: 1) to obtain initial estimates of intervention effect- measured by pre-intervention to post-intervention differences in perceived behavioral control for adherence, intention to adhere, and adherence behavior - to inform design of a future trial powered to detect a clinically significant effect of smart-phone medication reminder application use on adherence to oral medications; and 2) to examine the relationships among perceived behavioral control for adherence, intention to adhere, and adherence behavior. A pre-post single group design will be used. Data will be collected weekly for 4 weeks before introduction of the intervention and for 8 weeks following introduction of the intervention. Analytic approaches will include descriptive statistics and generalized estimating equation (GEE) modeling.

Official Title
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Use of a Smart-phone Medication Reminder Application to Promote Adherence to Oral Medications by Adolescents and Young Adults(AYA) With Cancer

Conditions
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Neoplasms

Participation Criteria
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Eligibility Criteria
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Inclusion criteria: 1)15-29 year olds receiving treatment for any type of cancer, either primary or recurrent/relapsed disease. 2) Patient has completed at least one month of therapy 3)Patient is expected to remain on therapy for 3 month duration of study 4) Patient has an iPhone, iPad, or iTouch running iOS 4.0 or later 5) Patient is willing to use a smart-phone medication reminder application- Exclusion Criteria: 1)Patients who are unable to speak/read/write English as required for use of smart-phone medication reminder application and completion of study measures.

Ages Eligible for Study
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Minimum Age: 15 Years
Maximum Age: 29 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Feasibility and Acceptability of Using a Smart-phone Medication Reminder Application to Promote Adherence to Oral Medications by AYA With Cancer. | Feasibility was assessed through participants' application usage and responses to self-reported questions about their use of the application. Acceptability was assessed through participants' perceived ease of use and perceived usefulness of the application. | ongoing study weeks 5-12 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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neoplasms, adolescent, young adult, medication adherence