Is the Measured Diameter of the Optic Nerve Sheath by Cerebral Scan in Patients With Early-phase Meningeal Hemorrhage, Due to a Ruptured Aneurysm, a Prognostic 6-month Mortality Factor ?

Study Overview
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Brief Summary
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Sub Arachnoid Hemorrhage (SAH) is a public health concern because of its high incidence (7/100 000 inhab.), its mortality rate (25%), and its morbidity rate (50%).

Detailed Description
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Sub Arachnoid Hemorrhage (SAH) is a public health concern because of its high incidence (7/100 000 inhab.), its mortality rate (25%), and its morbidity rate (50%). Prognostic tools are indispensable in guiding and optimizing the care of these patients. Some diagnostic factors have been identified (e.g. age, comorbidities, ACSOS , GCS, ICP, occurrence of complications) as well as some classification schemes used for grading seriousness of the disease (Hunt and Hess, World Federation of NeuroSurgery). A tool that is simple, reliable, reproducible, non costly, non invasive, and simple to perform (including remote methods and without changing planned patient care) would be ideal. The measurement of the Optic Nerve Sheath Diameter (ONSD,) correlated by MRI and ultrasound in previous studies, with intra-cranial pressure (ICP: a fundamental prognostic factor for SAH) could be one of these tools. This measurement, previously demonstrated using ultrasound, could be carried out at the time of the patient's initial cerebral scan. In practice, at admission each patient undergoes a cerebral CT scan much more often than an ultrasound (faster, less costly, less technical training required). Two preliminary studies seem to suggest that this measurement of ONSD on CTc is a predictive factor for morbi-morbidity in patients having serious traumatic skull fractures.The measurement is reliable, reproducible, non invasive, and non costly, with good sensitivity and specificity. Proving that it is also applicable to SAH could be particularly useful.

Official Title
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Is the Measured Diameter of the Optic Nerve Sheath by Cerebral Scan in Patients With Early Phase Meningeal Hemorrhage Due to a Ruptured Aneurysm a Prognostic 6-month Mortality Factor?

Conditions
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Subarachnoid Hemorrhage

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients 18 years or older Patient admitted to the Neurosurgical Urgent Care Unit for SAH following a ruptured aneurysm Patients or one of their loved ones providing written informed consent Patients with healthcare coverage Exclusion Criteria: Unavailability of a CTc in the initial phase (within the first 12 hours) or absence of 1-mm slices from the scan Trauma to the optic globe or optic nerve pathology Preexisting anomalies of ICP or history of neurosurgical cerebral pathologies SAH of non aneurysm origin (e.g. arterio-venous malformation (AVM), tumor, trauma, sepsis) Patients under legal protection

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| patient survival | patient survival | month 6 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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optic nerve sheath, meningeal hemorrhage, early phase, prognostic