Determining the Effect of Vitamin D, Dyslipidemia and Microvascular in Patients With Type 2 Diabetes

Study Overview
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Brief Summary
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This study looked at the effect of vitamin D levels on the complications of type 2 diabetes and the fat profile of patients with diabetes.Participants in this study were divided into two groups. One group included participants with vitamin D deficiency and the other group did not.The first group receives 50,000 units of oral vitamin D 3 daily for up to 8 days.

Official Title
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Determining the Effect of Vitamin D, Dyslipidemia and Microvascular in Patients With Type 2 Diabetes

Conditions
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Diabetes Mellitus, Type 2

Intervention / Treatment
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* Drug: Vitamin D3
* Drug: Routine treatment


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients with type 2 diabetes Having conscious satisfaction Exclusion Criteria: Patients with a history of gastrointestinal surgery Patients with a history of renal failure Patients with a history of vitamin D intake and calcium-containing compounds Patients with a history of liver disease
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Patients with vitamin D deficiency<br>This group receives 50,000 units of vitamin D3 daily for up to 8 days until the serum level of vitamin D reaches above 30 ng/ml. | Drug: Vitamin D3<br>* For up to 8 days, 50,000 units of vitamin D3 are given daily to patients in the first group so that the serum level of vitamin D reaches above 30 g / ml.<br>|
| Active Comparator: Patients without vitamin D deficiency<br>Participants in this group receive only their usual treatments | Drug: Routine treatment<br>* In this group, patients receive their usual medications and treatments<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Vitamin D serum levels | Vitamin D serum levels measured by blood tests | up to 1 year | 
| Triglyceride | Level of blood triglycerides measured by a blood test | up to 1 year | 
| Blood cholesterol levels | Blood cholesterol levels measured by a blood test | up to 1 year | 
| HDL | Blood HDL levels measured by a blood test | up to 1 year | 
| LDL | Blood LDL levels measured by a blood test | up to 1 year | 
| Fasting blood glucose | Fasting blood glucose levels measured by a blood test | up to 1 year | 
| Neuropathy | Neuropathy based on United Kingdom Screening TEST | up to 1 year | 
| Nephropathy | Nephropathy based on albumin excretion evaluation | up to 1 year | 
| Retinopathy | Retinopathy based on an ophthalmologist's examination | up to 1 year | 
| blood pressure | Systolic and diastolic blood pressure measured by Sphygmomanometer | up to 1 year | 
| HBA1C | Blood sugar levels measured in the last three months measured by blood test | up to 1 year |