Cases With Traumatic and Non Traumatic Brain Damage Treated in the Intensive Care

Study Overview
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Brief Summary
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Cases of traumatic and nontraumatic brain damage have high rates of morbidity and mortality. In this study of cases being treated in the ICU for a diagnosis of brain damage, it was aimed to evaluate the relationship between mortality and the distribution of reason for and resulting type of brain damage and to determine other factors affecting mortality.

Detailed Description
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After local ethics committee approval, a total of 1004 patients treated in the ICU in a 2-year period were retrospectively reviewed. 135 patients, determined with traumatic or nontraumatic brain damage, with a more than 24-hour stay in the ICU, included the study. Reasons for brain damage were determined as brain damage associated with pure head trauma (Group HT), head trauma accompanying general body trauma (Group HT+GBT) and spontaneous haemorrhage (Group SH). The type of brain damage was defined from the radiological diagnosis as subarachnoid haemorrhage, intracranial haemorrhage (ICH), subdural haematoma(SDH), epidural haematoma(EDH), skull fracture, brain contusion or a combination of these (COM).

Official Title
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Distribution and Mortality Factors of Cases With Traumatic and Non Traumatic Brain Damage Treated in Intensive Care; Retrospective Clinical Trial

Conditions
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Brain Injuries

Intervention / Treatment
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* Other: type of the brain injury
* Other: type of the brain injury
* Other: type of the brain injury
* Other: type of the brain injury
* Other: type of the brain injury
* Other: type of the brain injury


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients treated in the ICU with the diagnose of traumatic or nontraumatic brain damage, with a more than 24-hour stay. Exclusion Criteria: Patients admitted less than 24 hour.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients with body and head trauma<br>type of the brain injury in patients with brain damage associated both general body and head trauma | Other: type of the brain injury<br>* epidural hematoma<br>Other: type of the brain injury<br>* subdural hematoma<br>Other: type of the brain injury<br>* subarachnoid hematoma<br>Other: type of the brain injury<br>* intraparenchymal hematoma<br>Other: type of the brain injury<br>* scull fracture<br>Other: type of the brain injury<br>* brain contusion<br>|
| Patients with pure head trauma<br>type of the brain injury in patients with brain damage associated pure head trauma | Other: type of the brain injury<br>* epidural hematoma<br>Other: type of the brain injury<br>* subdural hematoma<br>Other: type of the brain injury<br>* subarachnoid hematoma<br>Other: type of the brain injury<br>* intraparenchymal hematoma<br>Other: type of the brain injury<br>* scull fracture<br>Other: type of the brain injury<br>* brain contusion<br>|
| Patients with spontaneous hemorrhage<br>type of the brain injury in Patients with brain damage associated spontaneous hemorrhage | Other: type of the brain injury<br>* epidural hematoma<br>Other: type of the brain injury<br>* subdural hematoma<br>Other: type of the brain injury<br>* subarachnoid hematoma<br>Other: type of the brain injury<br>* intraparenchymal hematoma<br>Other: type of the brain injury<br>* scull fracture<br>Other: type of the brain injury<br>* brain contusion<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| number of patients by brain damage types | distribution of the patients with brain damage over the brain damage reasons | 2 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of factors effecting the mortality | duration time of intubation, duration time in the ICU, APACHE scores, GCS scores. | 2 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Traumatic Brain Injury, Brain Damage, Mortality, C10.228.140.199