Measuring of Neuro-visual Functionality With Ocusweep

Study Overview
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Brief Summary
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The aim of this study is to measure visual acuity, contrast sensitivity and visual field by SAP-method using a novel device Ocusweep compared to currently widely used methods. Addition to that, the aim is to validate a novel perimetry method (Visual Search Test, VST) which is based on reaction times in visual decision- making task, where the subject is allowed to move eyes and where the fixation is verified by the subject himself in contrast to standard automatic perimetry (SAP) where prolonged stationary fixation and external fixation monitoring apparatus is required. Reaction-time based visual field device Ocusweep is compared to generally used SAP methods. Those tests will be done for healthy volunteers and for persons with diagnosed eye or brain disease. Ocusweep OcuRT vision based choice reaction time test is validated for test repeatability and compared to Trail Making Test (TMT), Useful Field of View (UFOV) and Vienna Test System (VTS) reaction time tests. To evaluate the ability to detect unreliable results, OcuRT test is also done under cognitive load and with instructions to cheat the test.

Official Title
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Measuring of Neuro-visual Functionality With New Human Visual System Device Ocusweep

Conditions
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Visual Impairment

Intervention / Treatment
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* Device: Ocusweep
* Device: Ocusweep OcuRT


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Healthy volunteers Persons suffering diagnosed eye disease Persons suffering diagnosed brain disease Exclusion Criteria: No diabetes Only one diagnosed disease

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 95 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: LEA numbers, Pelli-Robson, Octopus<br>Comparable generally used method for measuring visual acuity, contrast sensitivity and visual field. | Device: Ocusweep<br>* A novel reaction-time based visual field device.<br>Device: Ocusweep OcuRT<br>* Vision based choice reaction time test method<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual acuity | Visual acuity is measured as logMAR unit at the one visit for each patient using a novel reaction-time based visual field device and comparable method. | One visit per one patient (1h/visit) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Contrast sensitivity | Contrast sensitivity is measured as logCS unit at the one visit for each patient using a novel reaction-time based visual field device and comparable method. | One visit per one patient (1h/visit) | 
| Reaction time visual field | Reaction time is measured using a novel reaction-time based visual field device and compared with generally used visual field program. | One visit per one patient (1h/visit) | 
| Vision based choice reaction time | Reaction time is measured with Ocusweep OcuRT test three times to asses repeatability of the test. OcuRT reaction time results will be compared to Trail Making Test (TMT), Useful Field of View (UFOV) and Vienna Test System (VTS) reaction time tests. To evaluate the ability to detect unreliable results, OcuRT will also be done under cognitive load and with instructions to cheat the test. | One visit per one test subject (1h/visit) |