Cardiac Function and Inspiratory Muscles Performance

Study Overview
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Brief Summary
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The purpose of this study is to determine whether ejection fraction and peak oxygen uptake have correlation on inspiratory muscle strength, chest wall volumes and quality of life in individuals with heart failure.

Official Title
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Correlation Between Cardiac Function and Inspiratory Muscles Performance, Chest Wall Volumes and Quality of Life in Individuals With Heart Failure

Conditions
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Heart Failure

Intervention / Treatment
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* Other: Physical evaluation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Will be included individuals diagnosed with heart failure, both sexes, aged 18-65 years; hemodynamically stable (systolic blood pressure ≤ 140 mmHg; diastolic blood pressure ≤ 90 mmHg; heart rate = 90 bpm); self-reported sedentary. Exclusion Criteria: Will be excluded individuals with unstable angina were excluded; acute myocardial infarction or previous surgery up to three months before the survey; musculoskeletal changes, respiratory or chronic metabolic diseases; treatment with steroids, hormones or chemotherapy; gestation; smokers and former smokers assets or liabilities; inability to comply with verbal commands appraiser or unsuitability to the evaluation devices.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| G1<br>High or normal left ventricular ejection fraction | Other: Physical evaluation<br> <br> |
| G2<br>Moderate left ventricular ejection fraction | Other: Physical evaluation<br> <br> |
| G3<br>Reduced left ventricular ejection fraction | Other: Physical evaluation<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Correlation between left ventricular ejection fraction and peak oxygen uptake on inspiratory muscle strength as assessed by echocardiography, ergospirometer and mouth pressure maneuver, respectively |  | through study completion, an average of 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Correlation between left ventricular ejection fraction and peak oxygen uptake on chest wall volumes as assessed by echocardiography, ergospirometer and opto-electronic plethysmography, respectively |  | through study completion, an average of 6 months | 
| Correlation between left ventricular ejection fraction and peak oxygen uptake on quality of life as assessed by echocardiography, ergospirometer and Minnesota Living with Heart Failure Questionnaire, respectively |  | through study completion, an average of 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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quality of life, left ventricular ejection fraction, peak oxygen uptake, respiratory muscles