Practice of Sedation and Analgesia in Patients With Severe Brain Injury in China

Study Overview
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Brief Summary
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Sedation and analgesia is necessary management for patients in the intensive care units. The high-level studies of sedation and analgesia in China are still deficient, especially in patients with brain injuries who even have been excluded from the relevant studies.

Detailed Description
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Sedation and analgesia is necessary management for patients in the intensive care units. The high-level studies of sedation and analgesia in China are still deficient, especially in patients with brain injuries who even have been excluded from the relevant studies. In the present study, a multicenter, 1-day point cross-sectional study about the sedation and analgesia among patients in China, particularly brain-injured will be investigated. The objectives are to investigate sedation and analgesia among patients in China and to compare sedation and analgesia between brain injuries and other patients.

Official Title
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A Survey on the Practice of Sedation and Analgesia Among Patients With Severe Brain Injury in China: a Prospective Observational Study

Conditions
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Intensive Care Unit

Intervention / Treatment
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* Diagnostic Test: The Glasgow Coma Scale (GCS)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All adult patients admitted to the participating ICUs on the investigation day Exclusion Criteria: Age under 18 years Less than 24 hours of ICU stay before screening Taking part in other studies

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: The Glasgow Coma Scale (GCS)|Use the common GCS, RASS and self-reported pain assessment for evaluating consciousness, agitation/sedation and analgesia.|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Performance of sedation assessment | The percentage of patients receiving sedation assessment | The previous 24 hours prior to the on-site investigation | 
| Performance of pain assessment | The percentage of patients receiving pain assessment | The previous 24 hours prior to the on-site investigation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Use of sedatives | The percentage of patients receiving sedatives | The previous 24 hours prior to the on-site investigation | 
| Use of analgesics | The percentage of patients receiving analgesics | The previous 24 hours prior to the on-site investigation | 
| ICU mortality | The percentage of patients dead in the ICU | Within 60 days after on-site investigation | 
| Hospital mortality | The percentage of patients dead in the hospital | Within 60 days after on-site investigation | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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severe brain injuries, sedation and analgesia, intensive care unit, survey