İntraoperative Awareness Under General Anesthesia

Study Overview
=================
Brief Summary
-----------------
Intraoperative awareness which means the recall of experiences recorded in patients' memories during general anesthesia in the postoperative period is an important issue in anesthesia practice. The aims of this study are to investigate the incidence and causes of awareness during general anesthesia, incidence of dreaming during anesthesia, intra-operative experiences of patients who report awareness, the risk factors that may be associated with awareness, to analyze the frequency of posttraumatic stress disorder in cases with awareness and possible awareness, the risk factors that may be associated with PTSD in Turkish adults. Adult patients will be evaluated 4 time following emergence (a) One hour after emergence, (b) Twenty four hour after emergence (c) One week after emergence (d) One month after emergence. The first interview will be made face-to-face in the recovery unit, and other interviews will be made by phone. Each interview will be conducted using the same structured interview (Brice Interview). Descriptive statistics will be used to determine the incidence of awareness. χ2 test will be used for comparison between groups. Logistic regression will be used to determine the risk factors associated with awareness and PTSD. We believe that this study will contribute to the prevention of the problem by determining the real frequency and causes of intraoperative awareness under general anesthesia, determining the experiences and results of patients, and analyzing the associated risk factors.

Official Title
-----------------
The Incidence of Intraoperative Awareness Under General Anesthesia in Adults: A Prospective, Multicenter Study

Conditions
-----------------
To Investigate the Incidence and Causes of Awareness During General Anesthesia, To Investigate the of Dreaming During Anesthesia, To Investigate the Intra-operative Experiences of Patients Who Report Awareness, To Investigate the Risk Factors That May be Associated With Awareness, To Analyze the Frequency of Posttraumatic Stress Disorder in Cases With Awareness and Possible Awareness, To Investigate the Risk Factors That May be Associated With Posttraumatic Stress Disorder

Intervention / Treatment
-----------------
* Other: General anesthesia


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: ASA I-IV adult patients who will receive general anesthesia and are scheduled to be extubated postoperatively, Exclusion Criteria: ASA V patients Patients below 18 years of age, Patient who can not give informed consent, Patients who have known psychological or psychiatric problems, Patients who are not suitable for postoperative follow-up

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Adult patients age above 18 years<br>ASA I-IV adult patients over 18 years of age who will receive general anesthesia and are scheduled to be extubated postoperatively, who can give informed consent, have no known psychological or psychiatric problems, and who are suitable for postoperative follow-up. | Other: General anesthesia<br>* Following emergence from general anesthesia, patients will be evaluated at 4 different timepoints; (a) One hour after emergence, (b) Twenty four hour after emergence (c) One week after emergence (d) One month after emergence. The first interview will be made face-to-face in the recovery unit, and other interviews will be made by phone.<br>* Other names: Modified Brice Interview;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Modified Brice interview | This interview consists of 5 questions. Patients will be evaluated at 4 different timepoints following emergence. First interview will be made face-to-face in the recovery unit, and other interviews will be made by phone. | One hour after emergence | 
| Modified Brice interview | This interview consists of 5 questions. Patients will be evaluated at 4 different timepoints following emergence. First interview will be made face-to-face in the recovery unit, and other interviews will be made by phone. | Twenty four hour after emergence | 
| Modified Brice interview | This interview consists of 5 questions. Patients will be evaluated at 4 different timepoints following emergence. First interview will be made face-to-face in the recovery unit, and other interviews will be made by phone. | One week after emergence | 
| Modified Brice interview | This interview consists of 5 questions. Patients will be evaluated at 4 different timepoints following emergence. First interview will be made face-to-face in the recovery unit, and other interviews will be made by phone. | One month after emergence. | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
intraoperative awareness, general anesthesia, dreaming, incidence