Benefits of Post-Pyloric Feeding Tubes in Critically Ill Patients

Study Overview
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Brief Summary
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The purpose of this study is to determine the benefit of feeding critically-ill patients beyond the stomach (post-pyloric). Furthermore, because of the advent of two new post-pyloric feeding tubes (Tiger 2 and Syncro BlueTube) designed to improve post-pyloric placement, the investigators will be evaluating the benefits of those two tubes as well.

Official Title
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Benefits of Post-Pyloric Feeding Tubes in Critically Ill Patients

Conditions
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Critical Illness

Intervention / Treatment
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* Device: Transpyloric feeding tubes (Nasogastric Tube (NG tube), Tiger2, Syncro BlueTube)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients admitted to the ICU who are deemed by the attending critical care physician to warrant tube feeds and expected to receive tube feeds for more than three days

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Transgastric tube<br>Nasogastric (NG tube) | Device: Transpyloric feeding tubes (Nasogastric Tube (NG tube), Tiger2, Syncro BlueTube)<br>* To determine the benefits of utilizing one type of transpyloric tube over another.<br>* Other names: Syncro BlueTube;|
| Transpyloric tube - Tiger2<br>Self-propelled by paristaltic waves of the stomach | Device: Transpyloric feeding tubes (Nasogastric Tube (NG tube), Tiger2, Syncro BlueTube)<br>* To determine the benefits of utilizing one type of transpyloric tube over another.<br>* Other names: Syncro BlueTube;|
| Transpyloric tube - Syncro BlueTube<br>Magnetically placed | Device: Transpyloric feeding tubes (Nasogastric Tube (NG tube), Tiger2, Syncro BlueTube)<br>* To determine the benefits of utilizing one type of transpyloric tube over another.<br>* Other names: Syncro BlueTube;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To determine whether transpyloric feeds are superior to transgastric feeds with regard to ability to give calories and meet nutritional goals. | To determine the time to goal calories. To determine the number and qualitative aspect of tracheal aspirations. To determine the time to initiate tube feeds once the decision has been made to place a tube, the number of x-rays required for placement, the time required for placement, the number of times tube needs to be replaced. | one year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To determine the benefits of utilizing one type of transpyloric tube over another. One placed in the transpyloric position magnetically; the other propelled by peristalsis itself. | Benefits include shorter time to appropriate placement and quicker time to goal tube feed rate. | one year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Enteral Feeds, Supplemental Feeds, Transpyloric Tube, Nasogastric Tube