Comparing the Visual Outcome, Visual Quality, and Satisfaction Among Three Types of Multi-focal Intraocular Lenses

Study Overview
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Brief Summary
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The investigators are going to Investigate the comparative efficacy of the patients who underwent cataract surgery with three different multifocal IOLs.

Detailed Description
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Going to analyze the clinical results of 60 patients who underwent bilateral cataract surgery and multifocal IOL implantation. The patients were divided into the following three groups: Mix-and-Match, EDOF, and Trifocal. The clinical assessments included uncorrected near, intermediate, distance and best corrected distance visual acuity, defocus curves, contrast sensitivity, and reading speed. Patient satisfaction was evaluated by questionnaire. All outcomes were compared among the three groups.

Official Title
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Comparing the Visual Outcome, Visual Quality, and Satisfaction Among Three Types of Multi-focal Intraocular Lenses

Conditions
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Cataract

Intervention / Treatment
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* Device: Mix-and-Match
* Device: EDOF
* Device: Trifocal


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients with bilateral senile cataracts and the desire to be spectacle-free for all distances Exclusion Criteria: Patients younger than 21 years, had corneal astigmatism >1.00 D, previous ocular surgery or trauma, or ocular disease other than cataracts

Ages Eligible for Study
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Minimum Age: 21 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Mix-and-Match group<br>Cataract surgery and implantation of a Tecnis ZKB00 multifocal IOL with +2.75 D add power (Abbott Medical Optic Inc., Santa Ana, CA) in the dominant eye, and a Tecnis ZLB00 multifocal IOL with +3.25 D add power (Abbott Medical Optics Inc.) in the non-dominant eye. | Device: Mix-and-Match<br>* Phacoemulsification and implantation of Tecnis ZKB00 multifocal IOL with +2.75 D add power (Abbott Medical Optic Inc., Santa Ana, CA) in the dominant eye, and a Tecnis ZLB00 multifocal IOL with +3.25 D add power (Abbott Medical Optics Inc.) in the non-dominant eye.<br>|
| Active Comparator: EDOF group<br>Cataract surgery and implantation of Tecnis Symfony ZXR00 trifocal IOLs (Abbot Medical Optics Inc.) in both eyes. | Device: EDOF<br>* Phacoemulsification and implantation of Tecnis Symfony ZXR00 trifocal IOLs (Abbot Medical Optics Inc.) in both eyes.<br>|
| Active Comparator: Trifocal group<br>Cataract surgery and implantation of FineVision PodFT IOLs (PhysIOL SA) in both eyes. | Device: Trifocal<br>* Phacoemulsification and implantation of FineVision PodFT IOLs (PhysIOL SA) in both eyes.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative uncorrected near, intermediate, and far visual acuity. | logMAR | At 1month and 3months after surgery | 
| Postoperative contrast sensitivity in the three groups. | 3, 6, 12, and 18 cycles per degree using a CSV-1000 chart (Vector Vision, reenville, OH) under photopic (85 cd/m2), mesopic ( 3 cd/m2), and mesopic with glare conditions | Postoperative 3 months | 
| Postoperative satisfaction questionnaire. | patients were shown images and asked to rate the frequency, degree, and discomfort related to the visual artifacts as none, minimal, moderate, or severe (0, 1, 2, or 3 points for the respective levels). The mean score was calculated. | Postoperative 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative refractive outcome | Diopter | Postoperative 3 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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multifocal intraocular lens