Multicenter Descriptive Study of the Patient Clinical Profile That Begins With Disseminated Her 2 + Breast Cancer or Develops a Metastasis After or During the Adjuvant Therapy

Study Overview
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Brief Summary
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This is an observational, cross-sectional study that the main objective is to describe the patient clinical profile that begins with disseminated Her 2+ Breast Cancer or develops a metastasis after or during the adjuvant treatment.

Official Title
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Observational, Cross-sectional, Multicenter Descriptive Study of the Patient Clinical Profile That Begins With Disseminated Her 2 + Breast Cancer or Develops a Metastasis After or During the Adjuvant Therapy (PRIMHER)

Conditions
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Disseminated HER2+ Breast Cancer

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Women with 18 years or over Patients with disseminated breast cancer histologically or cytological confirmed, who begins with Her 2+ metastatic breast cancer or develops a metastasis after or during the adjuvant therapy Patients treated in first line treatment in metastatic disease. Patients who have positive Her 2 receptor test Patients who have given their written informed consent Exclusion Criteria: Patients who are participating in other studies

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The Patient Clinical Profile (General Clinical Data and Breast Cancer Characteristics) | General clinical data: age, weigh, height, Perfomance Status (ECOG Eastern Cooperative Oncology Group, runs from 0 to 5, with 0 denoting perfect health and 5 death), Breast cancer characteristics: familiar history of breast cancer, initial diagnostic (localized or disseminated), age at diagnostic, TNM (tumor node metástasis), tumor size, node involvement, primary tumor surgery, HER2 overexpression, histological Classification (grades I, II and III,determines the urgency and aggressiveness of treatment, as the higher grades do tend to correspond to poorer survival rates and prognosis), time from the primary breast cancer to distant relapse, description and localization of metastasis | 1 day (there is no follow-up, it is a cross-sectional study) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Adjuvant Treatment in Primary Breast Cancer: Chemotherapy (Treatment With TAC-Docetaxel, Adriamicine and Cyclophosphamide), Hormonal Therapy Anti-HER Biological Therapy |  | one day (there is no follow-up, it is a cross-sectional study) | 
| The Pattern of Treatment in Metastatic Breast Cancer: Chemotherapy, Hormonal Therapy Anti-HER Biological Therapy |  | one day (there is no follow-up, it si a cross-sectional study) | 
| Adjuvant Treatment and Age | Adjuvant treatment and clinical profile (age) The patients analysed in this outcome are patients initially diagnosed with localized breast cáncer (N=66) | one day (there is no follow-up, it is a cross-sectional study) | 
| Adjuvant Treatment-Physical Activity | Adjuvant treatment and clinical profile (Physical activity) The patients analysed in this outcome are patients initially diagnosed with localized breast cáncer (N=66) | one day (there is no follow-up, it is a cross-sectional study) | 
| Adjuvant Treatment-Node Affectation | Adjuvant treatment and clinical profile (Node affectation) The patients analysed in this outcome are patients initially diagnosed with localized breast cáncer (N=66) | one day (there is no follow-up, it is a cross-sectional study) | 
| Disseminated Breast Cancer Treatment-Age | Analyse disseminated Breast Cancer treatment and clinical profile (age) | one day (there is no follow-up, it is a cross-sectional study) | 
| Disseminated Breast Cancer Treatment-physical Activity | Analyse disseminated Breast Cancer treatment and clinical profile (physical activity) | one day (there is no follow-up, it is a cross-sectional study) | 
| Disseminated Breast Cancer Treatment-Smoking | Analyse disseminated Breast Cancer treatment and clinical profile (Smoking) | one day (there is no follow-up, it is a cross-sectional study) |