Veteran Primers for CRC Screening

Study Overview
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Brief Summary
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This is a prospective, randomized controlled trial that will evaluate the effectiveness of primer postcards sent two weeks prior to the mailing of a FIT kit in improving adherence to annual CRC screening.

Detailed Description
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Veterans eligible for enrollment into the trial will be randomized in a 1:1 allocation using permuted block randomization (with random block sizes of 4 and 8) to the following interventions: Active arm: Primer Intervention Type: Other Intervention Description: Mailed postcard notifying Veteran of upcoming FIT kit receipt for annual CRC screening Control arm: No primer a. Intervention Type: No intervention Randomization will be stratified within arms by prior screening status (prior screener vs. never screener) Our primary outcome of interest is the return rate at three months post randomization. Our secondary outcome of interest is the return rate at six months post randomization. Enrollment in the trial will occur between May 1, 2021 and January 1, 2022.

Official Title
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Primers to Improve Adherence to Annual CRC Screening Among Veterans: A Randomized Control Trial

Conditions
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Colorectal Cancer

Intervention / Treatment
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* Other: Primer


Participation Criteria
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Eligibility Criteria
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Eligible participants are automatically enrolled in this project. We are unable to enroll participants upon request. Inclusion criteria: Veteran Assigned to a primary care provider at the VA Puget Sound as of January 1, 2021 At least 1 year of prior data available (evidence of at least one outpatient visit) Due for annual colorectal (CRC) screening Exclusion criteria: Not scheduled for either a screening or diagnostic colonoscopy within the 12 weeks from assessment. Not currently receiving hospice care No record of recent death in the administrative data. No history of CRC or history of prior colectomy.

Ages Eligible for Study
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Minimum Age: 50 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Screening
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Active<br>Primer | Other: Primer<br>* Mailed postcard notifying Veteran of upcoming FIT kit for annual CRC screening.<br>|
| No Intervention: Control<br>No Primer | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Return proportion | Percent of returned FIT tests | 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Return proportion | Percent of returned FIT tests | 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Cancer screening, Behavioral economics, Adherence