The Role of Pulsed Dye Laser Therapy in the Management of Burn Scars

Study Overview
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Brief Summary
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The purpose of this study is to determine the effects (good or bad) of pulsed dye laser treatment in burn scar height, texture, redness and pliability in acute burn injury.

Detailed Description
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While the literature tends to support the use of laser therapy in the management of burn scars, there is a definite lack of appropriately powered, randomized controlled trials. Laser therapy can be quite expensive when compared to other treatment modalities for burn scars, and while promising, its true usefulness has yet to be conclusively demonstrated. For this reason, our research group is proposing the commencement of two randomized controlled trial pilot studies assessing the effects of pulsed dye laser (PDL) on burn scars. The objectives of this project will be to determine the effectiveness of pulsed dye laser therapy on burn scar vascularity, pliability, height and texture. It has been hypothesized that the PDL works on acute injury to decrease scar formation, and the fractional laser works on scar that is quiescent to promote remodelling. Therefore the investigators are proposing to study both acute injury and late burn scars. This project will compare the effects of each laser type, and will either help support or refute the assertion that laser therapy can be used to improve burn scars. Objectives: To determine the benefit of pulsed dye laser treatment in improving burn scar height, texture, vascularity and pliability in acute burn injury.

Official Title
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The Role of Pulsed Dye Laser Therapy in the Management of Burn Scars

Conditions
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Burn Scar

Intervention / Treatment
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* Procedure: pulsed dye laser


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: burn scar living in Winnipeg scar age one to 6 months Fitzpatrick I-III skin type Exclusion Criteria: open wound active infection previous scar treatment with steroid injection or interferon established disposition towards keloid scarring

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Proximal<br>part of scar proximal to heart | Procedure: pulsed dye laser<br>* laser energy<br>|
| Active Comparator: Distal<br>part of scar distal to heart | Procedure: pulsed dye laser<br>* laser energy<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Scar Characteristics | Examine characteristics of scar | six months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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burn, scar, laser