RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT

Study Overview
=================
Brief Summary
-----------------
The RSSearch® Registry is an international multi-year database designed to track SRS/SBRT (Stereotactic Radiosurgery/Stereotactic Body Radiation Therapy) utilization, treatment practices and outcomes to help determine, over time, the most effective use of these systems in management of patients with life threatening tumors and other diseases. (This study was formally called ReCKord and included the CyberKnife only; The ReCKord study continues as a CyberKnife subset of RSSearch.)

Detailed Description
-----------------
The Registry is designed to help SRS/SBRT (Stereotactic Radiosurgery/Stereotactic Body Radiation Therapy) users to understand utilization of and key treatment outcomes for these treatment approaches. Some of the objectives include: Allow participants to record information about usage of SRS/SBRT in everyday practice, including patient characteristics and disease information, treatment plans and outcomes Provide participants with ready access to data for publication of their own experience and as a tool for establishing collaborations with other participating sites Facilitate quality improvement efforts for individual treatment providers Understand the effectiveness of different treatment plans for different types of lesions, diseases and treatments The Registry tracks select outcomes for each condition treated by SRS/SBRT (for example, PSA for prostate cancer); the Registry also provides individual participants the ability to add additional outcomes for each and any condition of specific interest to their institutions. The Registry is hosted by Vision Tree, Inc who is an independent vendor of electronic registries; they are responsible for HIPAA compliance, including all security mechanisms. Patients will be enrolled prospectively. Some retrospective patient data is likely to be included in order to capture both short and longer term outcomes data.

Official Title
-----------------
Multi-Institution Registry of SRS/SBRT Procedures

Conditions
-----------------
Neoplasms, Arteriovenous Malformation of Central Nervous System, Trigeminal Neuralgia

Intervention / Treatment
-----------------
* Radiation: SRS/SBRT


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Diagnosis of benign or malignant tumors or other conditions deemed treatable by stereotactic radiosurgery or stereotactic body radiotherapy Willingness to sign an Informed Consent Document or verbally agree to participation Exclusion Criteria: There are no specific exclusion criteria, but patients who are unwilling to sign the ICD or who decline participation will not be included
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients being treated by SRS/SBRT<br>Patients with a condition being considered for treatment by SRS/SBRT | Radiation: SRS/SBRT<br>* Intervention varies by condition being treated.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Overall survival | Survival from time of treatment to death | Up to 5 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Local and distant recurrence | Calculated from time of treatment to recurrence | One to Five years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Radiosurgery, CyberKnife, Benign tumors, Malignant tumors, Cranial tumors, Extracranial tumors, Lung, Liver, Pancreas, Prostate, Stereotactic radiosurgery, Stereotactic body radiotherapy