Omega-3 Supplementation Combined With Endurance Training Improve Running Economy in Recreational Runners.

Study Overview
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Brief Summary
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Recreational male runners participated in 12 weeks training and omega-3 supplementation programme. Before starting and at the end of the 12-week cycle, the runners performed an increasing intensity treadmill test where oxygen uptake and VO2 peak were assessed.

Detailed Description
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40 healthy, recreational male runners participated in 12 weeks training and supplementation programme. The training protocol was built based on undulatory load manipulation 3:1, which was suggested to be effective to prevent overtraining and stress due to oscillations between volume/intensity. Throughout the study all participants took 4 identical-looking capsules per day (2 in the morning and 2 in the evening) containing either omega-3 fatty acids or medium chain triglycerides as placebo in total amount of 4g of fat per day. Before starting and at the end of the 12-week cycle, the runners performed an increasing intensity treadmill test where oxygen uptake and VO2 peak were assessed. Additionally, blood was collected to determine the concentrations of selected proteins (including eNOS, irisin, adiponectin) that may be associated with potential changes in participants' oxygen uptake during the treadmill test.

Official Title
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12 Weeks of Omega-3 Supplementation Combined With Endurance Training Improve Running Economy in Recreational Runners. The Potential Role of the Myokines-NO Pathway.

Conditions
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Effect of Omega-3 Supplementation on Exercise Performance and Muscle Tissue Functions

Intervention / Treatment
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* Dietary Supplement: Omega-3 supplementation in recreational runners


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: non smoking no chronic diseases no supplements and medicines personal best in 10km run between 35 and 59 min at the turn of 2016 and 2020 y Exclusion Criteria: -

Ages Eligible for Study
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Minimum Age: 29 Years
Maximum Age: 42 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Omega<br> | Dietary Supplement: Omega-3 supplementation in recreational runners<br>* Male recreational runners participated in 12 weeks of endurance training combined with omega-3 fatty acids supplementation. Before starting and at the end of the 12-week cycle, the runners performed an increasing intensity treadmill test where oxygen uptake and VO2 peak were assessed.<br>|
| Placebo Comparator: Placebo<br> | Dietary Supplement: Omega-3 supplementation in recreational runners<br>* Male recreational runners participated in 12 weeks of endurance training combined with omega-3 fatty acids supplementation. Before starting and at the end of the 12-week cycle, the runners performed an increasing intensity treadmill test where oxygen uptake and VO2 peak were assessed.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| changes in oxygen consumption during running test |  | between 10 and 25 minutes of the running test | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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omega-3, supplementation, endurance training, running