No Need for Neuromuscular Blockade in Daycase Laparoscopic Surgery

Study Overview
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Brief Summary
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This study analyse the need for neuromuscular blockade in consecutive routine laparoscopic procedures without standard use of neuromuscular blockade in an ambulatory laparoscopic surgery setting and analyse specific reasons for using neuromuscular blockade in individual patients. Furthermore, the study report the analgesic use in postoperative care unit and the discharge rate.

Detailed Description
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The study is retrospective, including consecutive patients in an unrestricted referral of patients undergoing laparoscopic cholecystectomy, umbilical and inguinal hernia repair. Inclusion period was from 01.04.2013 to 31.03.2015. All patients received general anesthesia using propofol (2 mg/kg) and remifentanil (1 μg/kg/min) for induction. In patients where tracheal intubation was required, this was done without use of neuromuscular blocking drug; otherwise a proseal laryngeal mask was used. For the maintenance of anesthesia, additional continuous infusion of propofol (3-5 mg/kg/h) and remifentanil (0.3-0.5 μg/kg/min) was used. Data were derived from a prospective local database on demographics, anesthetic methods and supplements (i.e. need for neuromuscular blockade) and postoperative needs for supplementary analgesics besides the postoperative standard analgesic regimen, number of hours stayed in the ambulatory surgery department, and discharge rate (including reasons for hospital admittance).

Official Title
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No Need for Neuromuscular Blockade in Day Case Standardised Laparoscopic Surgery. A Consecutive Retrospective Study

Conditions
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Cholecystitis, Inguinal Hernia, Direct, Umbilical Hernia

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients undergoing laparoscopic cholecystectomy, umbilical and inguinal hernia repair Exclusion Criteria: None

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of patients requiring neuromuscular blockade | Data derived from a prospective local database on need for neuromuscular blockade in patients undergoing laparoscopic cholecystectomy, umbilical and inguinal hernia repair. | At time of surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Analgesic use in postoperative care unit | Amount of opioids administered to the patients in the postoperative care unit | Within 6 hours after surgery | 
| Hours stayed in the postoperative care unit |  | 1 to 6 hours after surgery | 
| Maximum Visual analog score (VAS) for pain in the postoperative Care unit |  | 1 to 6 hours after surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Neuromuscular, Blockade, Surgery