Evaluation of Functional Outcomes After Laparoscopic Promontofixation (PFL).

Study Overview
=================
Brief Summary
-----------------
Prolapse of the pelvic organs is a common pathology in women with a strong impact on the quality of life. Its prevalence tends to increase due to increased life expectancy and obesity. The main treatment is surgical and involves all organ specialists dealing with pelvic-perineal functional disorders: urologists, gynecologists, digestive surgeons. Our team wishes to evaluate, on a cohort of patients operated at the Caen University Hospital, the functional uro-gynecologic, digestive and sexual results of pelvic organ prolapse (POP) repair by Laparoscopic Promontofixation (PFL) through symptoms and quality of life validated questionnaires (QoL). The analysis of the responses to these questionnaires will allow us to evaluate the functional results in the short and medium term (from 6 months to 5 years)

Detailed Description
-----------------
This is a retrospective cohort study conducted at the Universitary hospital of Caen in three surgical departments (gynecology, urology and digestive surgery). Patients who had a laparoscopic promontofixation will be asked to respond to validated questionnaires of symptoms and quality of life after their surgery (PFDI-20, ICIQ-SF, PFIQ-7) and satisfaction (PGI-I)

Official Title
-----------------
Evaluation of Functional Outcomes and Quality of Life After Laparoscopic Promontofixation (PFL). Unicentric Retrospective Cohort Study (PeSuLife)

Conditions
-----------------
Pelvic Organ Prolapse, Symptoms, Satisfaction, Quality of Life

Intervention / Treatment
-----------------
* Other: Evaluation of laparoscopic promontofixation


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients who have had a laparoscopic promotofixation for genital prolapse at the University Hospital of Caen between 2013 and 2018 in the departments of gynecology, urology and digestive surgery. Patient who received written information and agreed to participate in the study Exclusion Criteria: Minor patient, under guardianship, under trusteeship Patient not understanding French Refusal to participate in the study

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Evaluation of laparoscopic promontofixation|Evaluation of Functional Outcomes and Quality of Life After Laparoscopic Promontofixation (PFL). Unicentric Retrospective Cohort Study (PeSuLife)|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Effect of laparoscopic promontofixation on urogynecologic and digestive symptoms | The main objective is to collect the PFDI-20 score after the surgery. This score was developped to evaluate the genital, anorectal and digestive symptoms related to prolapse | 3 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Effect of laparoscopic promontofixation on urinary incontinence | Assessment of the ICIQ-SF score, a specific score developped to assess the impact urinary incontinence | 3 years | 
| Sexual impact of laparoscopic promontofixation | Evaluation of the PISQ-12 score after laparoscopic promontofixation. This score was developped specifically to evaluate sexual troubles in case of genital prolapse | 3 years | 
| Evaluation of quality of life after prolapse surgery | Evaluation of the quality of life using a score specifically developped in case of genital prolapse : the PFIQ-7 score | 3 years | 
| Assessment of patient satisfaction after surgery | Evaluation of the quality of life using the PGI-I score, developped to quantify the effect of urinary or prolapse treatments | 3 years | 
| Specific evaluation of functional outcomes of laparoscopic rectopexy in rectocele or elytrocele indications | Evaluation of the PFDI-20 score in women undergoing laparoscopic rectopexy | 3 years | 
| Comparison of the different scores according to the operative indication (anterior promontofixation, double promontofixation, rectopexy alone) | Comparison of the PFDI-20 scores according to the operative indication | 3 years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Pelvic Organ Prolapse, laparoscopic promontofixation, symptoms, Satisfaction, Quality of Life