Dose-response: Exercise Therapy on Hip Osteoarthritis

Study Overview
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Brief Summary
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Osteoarthritis is a common disease that causes muscle weakness, stiffness and instability. The disease reduces the opportunities for an active lifestyle. Exercise Therapy provides a well-documented effect on pain and function in patients with osteoarthritis of the hip. It is sought an optimal dose of exercise, in which this study will help to investigate. We hypothesize that an exercise program designed to have a high number of repetitions will benefit the outcome of the training in a more positive way than a low-repetition based program.

Official Title
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Dose-response: Exercise Therapy on Hip Osteoarthritis, a Pilot Study

Conditions
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Osteoarthritis, Hip

Intervention / Treatment
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* Other: High-Dosage Exercise Therapy
* Other: Low-Dosage Exercise Therapy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: At least three month since debut of the disease Age above 45 years Ability to complete the intervention Exclusion Criteria: Pain above 4 on VAS during gait Pregnancy Autoimmune disease Cardiovascular disease Respiratory disease Metabolic disease Neurological signs Planned hip-replacement surgery within the next year Received exercise therapy within the last 3 months

Ages Eligible for Study
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Minimum Age: 45 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: High-dosage-group<br> | Other: High-Dosage Exercise Therapy<br>* Structure of the exercise program done three times per week, for eight weeks: 5-10 minutes of global exercise (cycling, walking on treadmill etc.) Four local exercises (3 series of 30 repetitions) 5-10 minutes of global exercise (cycling, walking on treadmill etc.) Four local exercises (3 series of 30 repetitions) 5-10 minutes of global exercise (cycling, walking on treadmill etc.)<br>|
| Active Comparator: Low-dosage-group<br> | Other: Low-Dosage Exercise Therapy<br>* Structure of the exercise program done three times per week, for eight weeks: 5-10 minutes of global exercise (cycling, walking on treadmill etc.) Four local exercises (3 series of 10 repetitions) 5-10 minutes of global exercise (cycling, walking on treadmill etc.) Four local exercises (3 series of 10 repetitions) 5-10 minutes of global exercise (cycling, walking on treadmill etc.)<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| WOMAC Index of Osteoarthritis (questionnaire) | WOMAC Index of Osteoarthritis (questionnaire) | 0 weeks, 8 weeks, 6 months postinterventional | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| HAD questionnaire |  | 0 weeks, 8 weeks, 6 months postinterventional | 
| Tampa Scale for Kinesiophobia |  | 0 weeks, 8 weeks, 6 months postinterventional | 
| Squats | Number of squats completed in 30 seconds. | 0 weeks, 8 weeks, 6 months postinterventional | 
| Stairs | Time used to walk up and down 12 steps. | 0 weeks, 8 weeks, 6 months postinterventional | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Exercise therapy