The Effect of Age, Physical Fitness and a Single Bout of Aerobic Exercise on Motor and Cognitive Functions

Study Overview
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Brief Summary
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The proposed study is intended to examine the connection between two types of inhibition - cognitive and motor and the connection between motor inhibitory functions and a single bout of physical exercise in the context of age and physical fitness.

Official Title
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The Effect of Age, Physical Fitness and a Single Bout of Aerobic Exercise on Motor and Cognitive Functions

Conditions
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Physical Activity, Age-related Cognitive Decline

Intervention / Treatment
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* Behavioral: Aerobic Exercise
* Behavioral: Watching television


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Non-smokers Do not take psychiatric drugs on a regular basis Geriatric Depression Scale score less than 3 Mini-Mental State Examination score higher than 27 Healthy and able to exercise at medium intensity Exclusion Criteria: All others

Ages Eligible for Study
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Minimum Age: 22 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Highly fit older adults - Exercise<br>This will receive an aerobic exercise intervention | Behavioral: Aerobic Exercise<br>* Medium-intense 60% heart rate reserve (HRR) aerobic exercise on a treadmill for 30 minutes<br>|
| Active Comparator: Poorly fit older adults - Exercise<br>This arm will receive an aerobic exercise intervention | Behavioral: Aerobic Exercise<br>* Medium-intense 60% heart rate reserve (HRR) aerobic exercise on a treadmill for 30 minutes<br>|
| Active Comparator: Highly fit young adults - Exercise<br>This arm will receive an aerobic exercise intervention | Behavioral: Aerobic Exercise<br>* Medium-intense 60% heart rate reserve (HRR) aerobic exercise on a treadmill for 30 minutes<br>|
| Active Comparator: Poorly fit young adults - Exercise<br>This arm will receive an aerobic exercise intervention | Behavioral: Aerobic Exercise<br>* Medium-intense 60% heart rate reserve (HRR) aerobic exercise on a treadmill for 30 minutes<br>|
| Active Comparator: Highly fit older adults - TV<br>This arm will sit at rest and watch television | Behavioral: Watching television<br>* Sitting and watching television for 30 minutes<br>|
| Active Comparator: Poorly fit older adults - TV<br>This arm will sit at rest and watch television | Behavioral: Watching television<br>* Sitting and watching television for 30 minutes<br>|
| Active Comparator: Highly fit young adults - TV<br>This arm will sit at rest and watch television | Behavioral: Watching television<br>* Sitting and watching television for 30 minutes<br>|
| Active Comparator: Poorly fit young adults - TV<br>This arm will sit at rest and watch television | Behavioral: Watching television<br>* Sitting and watching television for 30 minutes<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Improvement in cognitive functions after exercise | This improvement will be measured through use of a vocal stroop test | One and a half hours | 
| Improvement in motor functions after exercise | This improvement will be measured through use of a multi-limb reaction time test | One and a half hours |