Predictive Factors and Autonomy Level Change

Study Overview
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Brief Summary
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The Alzheimer's disease or related disorders (ADRD) are among the most disabling diseases because of their main features such as cognitive impairment, loss of functional autonomy and behavioural disorders. In absence of current curative treatment, the identification of the predictive risk factors of progression of the disease, evaluated through its main symptoms, represents a major stake of public health. The investigators aimed at developing a database, which includes the patient medical records on a prospective basis, in collaboration with the medical and administrative personal and with the University hospital computer science department. The main objective is to study the predictive factors associated with the change of functional autonomy level, measured every 6 months to 12 months by phone, in a Memory Clinic. The study population would consist in about 1000 patients with ADRD. The length of follow-up of each patient will be 3 years.

Official Title
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Predictive Factors of the Autonomy Level Change Related to Memory Disorders

Conditions
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Memory Impairment

Intervention / Treatment
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* Other: The Lawton Instrumental Activities of Daily Living score (IADL), and the disability assessment of dementia score (DAD-6


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients who undergo a medical visit in the Memory Clinic for the 1st time Patients living at home or in housing Patients with memory impairment, at all stage of the disease Exclusion Criteria: Patients in institution Patients under legal protection Patients with a hearing or visual impairment, which dot not allow to carry out the examination

Ages Eligible for Study
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Minimum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Functional autonomy level collection<br>Collection of the Functional autonomy level every 6 - 12 months by phone | Other: The Lawton Instrumental Activities of Daily Living score (IADL), and the disability assessment of dementia score (DAD-6<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Functional autonomy level | The scores of Lawton Instrumental Activities of Daily Living (IADL) and of Disability Assessment of Dementia (DAD-6) | 3 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cognitive function level | Mini Mental Test examination (MMSE) | 3 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Cognitive function, Predictive factors, Alzheimer's disease or related disorders, Functional autonomy level