Examining Effects of Spinal Fusion on Outcomes Following Total Hip Replacement

Study Overview
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Brief Summary
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The purpose of the study is to explore the long term functional status of people who have had both a spinal fusion procedure and a total hip replacement.

Detailed Description
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The purpose of the study is to explore the long term functional status of people who have had both a spinal fusion procedure and a total hip replacement. Studies have found that those who have received spinal fusion may have worse outcomes following a total hip replacement than those who have not received a spinal fusion. The information obtained from this study will allow surgeons and researchers to better understand why some who've had a spine fusion have more complications post total hip replacement compared to those who did not have spinal fusion surgery.

Official Title
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Examining Effects of Spinal Arthrodesis on Outcomes Following Total Hip Arthroplasty

Conditions
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Spinal Fusion, Total Hip Replacement

Intervention / Treatment
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* Diagnostic Test: X-Ray Imaging
* Other: Gait Analysis


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Willing to come to the Civic Campus for a surgical follow-up visit Speaks English and/or French Group 1 patients must have had a spine fusion (SF) and total hip arthroplasty (THA) Group 2 patients must have had a total hip replacement (THA) and no history of spine fusion (SF) Group 3 patients must have had a spine fusion (SF) and no history of total hip arthroplasty (THA) Exclusion Criteria: Patient does not meet all 'inclusion' criteria Patient is unable to answer questionnaires Unable to get x-rays for other medical reasons Severe dementia
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Spine Fusion and Total Hip Replacement<br>Any patient who has undergone spine fusion (SF) and total hip arthroplasty (THA). Patients will undergo x-ray imaging and complete functional assessment questionnaires. Patients may additionally be asked to participate in a gait analysis in a Human Movement Laboratory. | Diagnostic Test: X-Ray Imaging<br>* X-Ray imaging in the following positions: Lateral standing, lateral seated, standard standing AP pelvis and AP pelvis lying down.<br>Other: Gait Analysis<br>* Certain patients may be asked to participate in a motion analysis procedure at the Human Movement Laboratory at the University of Ottawa. This procedure takes approximately 1.5 hours and you will only be asked to participate in the motion analysis procedure once. Participants will change into a custom-designed tight body suit, which has reflective markers on its surface for infrared video capture. Participants will then have pairs of surface electromyography (EMG) electrodes placed on certain areas of the skin on the legs and on the back. Wearing the EMG electrodes and marker suit, participants will perform 5 trials of walking on a level walkway, walking up and down a 3-step staircase, sitting from a standing position, and standing from a seated position.<br>|
| Total Hip Replacement Group<br>Any patient who has had THA only (no spine fusion surgery). Patients will undergo x-ray imaging and complete functional assessment questionnaires. Patients may additionally be asked to participate in a gait analysis in a Human Movement Laboratory. | Diagnostic Test: X-Ray Imaging<br>* X-Ray imaging in the following positions: Lateral standing, lateral seated, standard standing AP pelvis and AP pelvis lying down.<br>Other: Gait Analysis<br>* Certain patients may be asked to participate in a motion analysis procedure at the Human Movement Laboratory at the University of Ottawa. This procedure takes approximately 1.5 hours and you will only be asked to participate in the motion analysis procedure once. Participants will change into a custom-designed tight body suit, which has reflective markers on its surface for infrared video capture. Participants will then have pairs of surface electromyography (EMG) electrodes placed on certain areas of the skin on the legs and on the back. Wearing the EMG electrodes and marker suit, participants will perform 5 trials of walking on a level walkway, walking up and down a 3-step staircase, sitting from a standing position, and standing from a seated position.<br>|
| Spine Fusion Only Group<br>Any patient who has had spine fusion only (no hip replacement surgery). Patients will undergo x-ray imaging and complete functional assessment questionnaires. | Diagnostic Test: X-Ray Imaging<br>* X-Ray imaging in the following positions: Lateral standing, lateral seated, standard standing AP pelvis and AP pelvis lying down.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Implant positioning | Radiographic assessment (x-ray cup orientation measurements) | 6months or greater post-operative | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Hip dysfunction and osteoarthritis outcome score (HOOS) | Disease-specific quality of life measure | 6months or greater post-operative | 
| Oxford Hip Score | Disease-specific quality of life measure | 6months or greater post-operative | 
| SF-12 Questionnaire | Patient-reported overall quality of life measure | 6months or greater post-operative | 
| Oswestry low back disability questionnaire | Assessment of low back pain | 6months or greater post-operative |