Low Dose Ketamine VR Analgesia During Burn Care Procedure

Study Overview
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Brief Summary
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The purpose of the research is to see whether a low dose of ketamine, a medication used to reduce pain, enhances the effectiveness of a virtual reality video game, which is used as a form of distraction from pain during a painful burn care procedure.

Detailed Description
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This study is conducted in a hospital setting. It is a randomized controlled trial comparing the use of virtual reality distraction (VRD) and standard pain medications to the use of VRD, standard pain medications and a single low dose of ketamine as a means to reduce pain during a painful procedure in patients in the hospital.

Official Title
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Low Dose Ketamine to Enhance VR Analgesia During Painful Burn Care Procedure.

Conditions
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Burn

Intervention / Treatment
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* Behavioral: Virtual Reality


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age greater than or equal to 18 years Compliant and able to complete questionnaires No history of psychiatric disorder Not demonstrating delirium, psychosis or any form of Organic Brain Disorder Able to communicate verbally English-speaking IV access already in place Exclusion Criteria: Age less than 18 years Not capable of indicating pain intensity Not capable of filling out study measures Evidence of traumatic brain injury History of psychiatric disorder Demonstrating delirium, psychosis or any form of Organic Brain Disorder and associated memory problems Unable to communicate orally Receiving prophylaxis for alcohol or drug withdrawal Developmental disability Any face/head/neck injuries that interfere with the use of Virtual Reality equipment Non-English Speaking Extreme susceptibility to motion sickness Seizure history No IV access already in place

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: VR during burn care with Ketamine<br>Comparing Virtual Reality during burn care with Ketamine | Behavioral: Virtual Reality<br>* The patient will receive virtual reality during a burn care procedure<br>|
| Experimental: VR durin burn care without Ketamine<br>Comparing virtual reality during burn care without Ketamine. | Behavioral: Virtual Reality<br>* The patient will receive virtual reality during a burn care procedure<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Graphic Rating Scale (GRS) is a questionnaire consists of three subjective pain ratings, one subjective anxiety rating, and one rating of fun using the 0-10. |  | 1 day (Immediately following burn care ) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Virtual Reality Ketamine