Technology Interventions to Improve Outcomes After Knee Replacement

Study Overview
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Brief Summary
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The purpose of this study is to examine the effects of two technology interventions on health outcomes (e.g., physical activity, sedentary behavior, physical function, pain) after knee replacement at 2 and 5 months .

Detailed Description
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Two 8 week technology interventions will be examined and consist of the use of an app and/or website and regular calls. Assessments to examine outcomes will be completed at baseline, as well as at 2 and 5 months.

Official Title
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Reducing Sedentary Time Using an Innovative mHealth Intervention Among Total Knee Replacement Patients

Conditions
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Knee Arthroplasty

Intervention / Treatment
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* Behavioral: NEAT!2
* Behavioral: MyKneeGuide


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Be 40-79 years of age Had unilateral knee replacement within last 12 months Have an Android or iOS smartphone that is accessible and near them the majority of the day Be willing to download the study applications on their smartphone Spend at least 7 hours/day sitting Be English speaking Exclusion Criteria: Have any contraindications to activity Have a mobility limiting comorbidity Have a scheduled surgery within the next 6 months Do not have ≥4 days of valid accelerometer (>=10 hours) wear at baseline.

Ages Eligible for Study
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Minimum Age: 40 Years
Maximum Age: 79 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: NEAT!2<br>Participants randomized to this arm will use the NEAT!2 app and receive biweekly coaching calls for 8 weeks, and monthly maintenance calls between months 2-5. | Behavioral: NEAT!2<br>* 8 week sedentary reduction program<br>|
| Active Comparator: MyKneeGuide<br>Participants randomized to this arm will use the MyKneeGuide app/website and receive biweekly coaching calls for 8 weeks, and monthly maintenance calls between months 2-5. | Behavioral: MyKneeGuide<br>* 8 week surgery recovery education program<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Objectively Measured (Actigraph) Sedentary Behavior at 2 months | change sedentary behavior (<100 counts/minute) measured with Actigraph accelerometers between baseline and 3 months | 2 months - baseline | 
| Change in Objectively Measured (Actigraph) Sedentary Behavior at 5 months | change in sedentary behavior (<100 counts/minute) measured with Actigraph accelerometers between baseline and 6 months | 5 months - baseline | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Physical Function | Six minute walk test | 5 months after surgery | 
| Change in WOMAC Pain Subscale | WOMAC Pain Subscale - Scores range from 0 (no pain) to 20 (maximal pain) | 5 months after surgery | 
| Total physical activity measured by Actigraph accelerometers | objectively measured light, moderate and vigorous activity (>= 100 counts/min) by Actigraph accelerometers | 5 months after surgery | 
| Adherence to NEAT!2 calls | Number of calls completed | 2 months | 
| Adherence to NEAT!2 app | total days NEAT! app was used | 2 months | 
| Response to NEAT!2 prompts | percentage of notifications in which a transition from sitting to standing was detected | 2 months | 
| Change in physical function via chair stand test | Chair stand test | 5 months after surgery |