Perfusion Index Predicts Post-spinal Hypotension in Obese Parturients for Cesarean Section

Study Overview
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Brief Summary
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Hypotension is a common adverse effect of spinal anesthesia during caesarean section especially in obese patients. The aim of this study is to find out the correlation between baseline PI and post spinal hypotension in obese parturient.

Detailed Description
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Abstract Background Hypotension is a common adverse effect of spinal anesthesia during caesarean section especially in obese patients. The aim of this study is to find out the correlation between baseline PI and post spinal hypotension in obese parturient. Methods After approval of ethical committee and written informed consent, fifty Parturients aged between 18- 40 years, ASA I and II with term singleton pregnancies with BMI between 25 &40 admitted for cesarean section under spinal anesthesia were recruited in this prospective, observational study. The primary outcome is the correlation between baseline perfusion index and post spinal hypotension. The secondary outcome is the correlation between BMI and the incidence of hypotension after spinal anesthesia. Heart rate, blood pressure, perfusion index before and after spinal induction using Masimo device, level of sensory block, dose of ephedrine required to correct hypotension, dose of atropine required to correct bradycardia, incidence of nausea, vomiting and shivering were recorded.

Official Title
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Perfusion Index Predicts Post-spinal Hypotension in Obese Parturients for Cesarean Section-A Prospective Observational Study

Conditions
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Perfusion Index Predicts Post-spinal Hypotension

Intervention / Treatment
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* Procedure: correlation between baseline perfusion index and decrease in systolic blood pressure post spinal induction


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Fifty parturient Aged between 18- 40, ASA I and II With term singleton pregnancies With 25 ≥ BMI≤ 40 Conducted for cesarean section under spinal anesthesia Exclusion Criteria: Emergency cases, Placenta previa, Preeclampsia, Cardiovascular and cerebrovascular diseases, Patient with contraindication for regional anesthesia Patient with peripheral vascular diseases as DVT.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 40 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: correlation between baseline perfusion index and decrease in systolic blood pressure post spinal induction|correlation between baseline perfusion index and decrease in systolic blood pressure post spinal induction|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| correlation between baseline perfusion index and post spinal decrease in systolic blood pressure | correlation between baseline perfusion index and post spinal decrease in systolic blood pressure | 24 hours Postoperative | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| correlation between BMI and the incidence of post-spinal hypotension | correlation between BMI and the incidence of post-spinal hypotension | 24 hours Postoperative |