The Relationship Between Atrial Fibrillation and Frailty in Community-Dwelling Elderly

Study Overview
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Brief Summary
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Atrial fibrillation (AF) is the most common arrhythmias in clinical practice. Research investigating hospitalized patients have indicated there are deleterious effects of AF on patients besides the disease burden itself, including longer stay days for hospitalization, higher rates of frailty and increasing mortality rate after discharged in six months. In the community-dwelling research also found that elderly with AF have lower cognitive function, physical functional tests score and slower walking speed compared with the health ones. However, there is limited articles investigating the impact of AF on community-dwelling elderly, and the relationship between AF and frailty is also lack of discussion. According to the aged society and increasing prevalence of AF, the relationship between AF and frailty in community-dwelling elderly is warranting investigated.

Official Title
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The Relationship Between Atrial Fibrillation and Frailty in Community-Dwelling

Conditions
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Atrial Fibrillation, Frail Elderly Syndrome

Intervention / Treatment
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* Behavioral: Frailty status assessment


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Older than 65 years old Exclusion Criteria: diagnosed with the following disease Cardiovascular diseases: myocardial infarction, peripheral vascular diseases, aortic plaque Cerebrovascular disease: stroke, transient ischemic attack, emboli Heart failure Participants who cannot finish the trial

Ages Eligible for Study
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Minimum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Atria fibrillation (AF) group<br>Detection of AF during 30 seconds ECG assessment Once diagnosed with atrial fibrillation before Undergo the frailty status assessment | Behavioral: Frailty status assessment<br>* The Edmonton frail scale and Frailty criteria by Dr. Fried would be used to assess participants frailty status<br>|
| Non-AF group<br>No detection of AF during 30 seconds ECG assessment Undergo the frailty status assessment | Behavioral: Frailty status assessment<br>* The Edmonton frail scale and Frailty criteria by Dr. Fried would be used to assess participants frailty status<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Frailty status | Edmonton frail scale and Frailty criteria by Dr. Fried would be used to evaluate the frail status of the participants | The frail status assessment would take about 10 minutes | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Body composition | Maltron BioScan BF-920, Essex, UK would be used to assess participants' body composition | The body composition test would take about 10 minutes | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Atrial Fibrillation, Frailty status, Body composition, Sarcopenia