Sudden Sensorineural Hearing Loss in Wonju Severance Christian Hospital

Study Overview
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Brief Summary
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This study is to build a cohort of sudden sensorineural hearing loss (SSNHL) patients. When the patient visited the Department of otolaryngology clinic for hearing loss, we can diagnose the SSNHL following the result of pure tone audiometry and the history of the patient. The cohort is a system that tracks the hearing recovery status, timing, and degree of recovery of patients who received cocktail therapy with or without high-dose steroids, vasodilators, antiviral agents, and intratympanic steroid injections, satellite ganglion block, and hyperbaric oxygen therapy.

Official Title
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Prospective Cohort Study of Sudden Sensorineural Hearing Loss in Wonju Severance Christian Hospital

Conditions
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Hearing Loss, Sudden, Hearing Loss, Sensorineural, Hearing Loss, Cochlear, Hearing Loss, Hearing Loss, Central

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adult patients over 20 years of age A patient who visited Wonju Severance Christian Hospital, Department of Otolaryngology and was diagnosed with sudden hearing loss as it was confirmed that hearing loss of 30dBHL or more occurred within 3 days at three consecutive frequencies in a pure tone audiometry test. Those who have fully explained the purpose and content of the study and voluntarily agreed to the written consent Exclusion Criteria: If the patients do not want to or do not fill out the consent form If treatment is started for sudden hearing loss, but the possibility of other inner ear diseases including Meniere's disease is suspected due to repeated hearing loss, repeated recovery, dizziness, tinnitus, etc. Other cases where it is judged difficult to carry out the clinical trial due to the judgment of the person in charge of the above clinical trial

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 100 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Hearing outcome 1 week - PTA | Hearing change status near 1 weak after treatment start measured by pure tone audiometry1 | 1 week PTA | 
| Hearing outcome 3 weeks - PTA | Hearing change status near 3 weaks after treatment start measured by pure tone audiometry | 3 weeks PTA | 
| Hearing outcome 2 months - PTA | Hearing change status near 3 weaks after treatment start measured by pure tone audiometry | 2 month PTA | 
| Hearing outcome 3 months - PTA | Hearing change status near 3 months after treatment start measured by pure tone audiometry | 3 month PTA | 
| Hearing outcome 6 months - PTA | Hearing change status near 6 months after treatment start measured by pure tone audiometry, which is final. | 6 months PTA | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Electrolytes and chemistries after high dose steroid therapy | The results of blood tests of electrolytes and chemistries at 5 days after treatment start. (Na, K, Cl, CO2, BUN, Cr, Glucose, Amylase, Total protein, Albumin, AST, ALT, ALP, r-GT, Total Bilirubin) | 5 days electrolytes and chemistries | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Hearing Loss, Hearing Loss, sudden