Evaluation of the Prevalence and Risk Factors for Patients With Peri-implant Disease

Study Overview
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Brief Summary
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To investigate the prevalence and risk factors for peri-implant disease in partially edentulous patients rehabilitated with implants supported crown or bridge so as to provide evidence for clinical prevention and control.

Detailed Description
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The aim of the present study is to identify the prevalence of peri-implant disease in partially edentulous subjects treated with osseointegrated implants, using clinical parameters, as well as to analyse the possible disease association with demographic, behavioural, and biological risk variables.

Official Title
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The Prevalence and Risk Factors for Patients With Peri-implant Disease： A Prospective Study

Conditions
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Jaw, Edentulous, Partially

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Partially edentulous patients will implant at least one implant and will be restored with implant-supported fixed partial dentures and single crowns. Exclusion Criteria: Jaw radiotherapy treatment before and after implanting. Patients who have bruxism,xerostomia or the adjacent teeth periapical periodontitis. Patients who suffered with oral mucosa disease,or aggressive periodontitis or jaw defect. Patients who suffered with mental and psychological disease will influence their oral health normal maintenance.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| no peri-implant disease<br>The subjects who did not suffer from peri-implant disease. | |
| peri-implant disease<br>The subjects who suffered from peri-implant disease. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| peri-implant disease | Peri-implant disease includes Peri-implant mucositis and Peri-implantitis.Peri-implant mucositis: BoP/suppuration but no detectable bone loss. Peri-implantitis: BoP/suppuration and bone loss >2 mm. | at the 5 years after prosthetic loading. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Gingival Bleeding on Probing | Gingival bleeding on probing (BOP) using the modified sulcus bleeding index for implants. Scale equals 0 = No bleeding when periodontal probe is passed along the gingival margin;1 = Isolated bleeding spots visible;2 = Blood forms a confluent red line on the gingival margin;3 = Heavy or profuse bleeding. | at the first day,6 months 1,3 and 5 years after prosthetic loading. | 
| Pocket depths | PD will be measured from the free gingival margin to the base of the pocket and will be recorded in whole millimeters (mm). | at the first day,6 months 1,3 and 5 years after prosthetic loading. | 
| Marginal bone loss | Marginal bone loss will be assessed by periapical radiographs taken with the paralleling technique. | at the first day,6 months 1,3 and 5 years after prosthetic loading. | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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peri-implant disease, risk factors, prevalence