linjc16/ctgov huggingface dataset:
Ultrasound Assessment of Gastric Contents in Fasted Patient Undergoing Cholecystectomy

Study Overview
=================
Brief Summary
-----------------
Investigators assess the gastric contents by ultrasonography in fasted patients undergoing cholecystectomy.

Detailed Description
-----------------
Investigators evaluate the gastric volume through cross sectional area and amount of clear fluid using Perlas grade by ultrasound in the supine and right lateral position of fasted patients undergoing cholecystectomy. Full stomach is regarded if solid gastric contents are detected or clear fluid is more than 1.5 ml/kg. The frequency of full stomach will be analyzed.

Official Title
-----------------
Ultrasound Assessment of Gastric Contents in Fasted Patient Undergoing Cholecystectomy

Conditions
-----------------
Gastroparesis

Intervention / Treatment
-----------------
* Other: Ultrasound assessment of gastric contet


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients scheduled for cholecystectomy Exclusion Criteria: Presence of gastric anatomic abnormality or pathology A previous surgery of esophagus or stomach Current pregnancy Who could not lie in the right lateral decubitus (RLD) position

Ages Eligible for Study
-----------------
Minimum Age: 20 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Fasted patients for cholecyctectomy<br>The fasted patients for cholecyctectomy except exclusion criteria are included | Other: Ultrasound assessment of gastric contet<br>* Ultrasound assessment of gastric content is performed in fasted patient undergoing cholecystectomy.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of full stomach | The incidence of full stomach is assessed by using ultrasonography. | Before the induction of anesthesia | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cross sectional area of the stomach | The cross sectional area of the stomach is assessed by using ultrasonography in the supine and right lateral positions. | Before the induction of anesthesia | 
| Volume of stomach | The volume of stomach is assessed using the following formula; volume of stomach (mL) = 27.0 + 14.6 x cross-sectional area (right lateral position) - 1.28 x age. | Before the induction of anesthesia | 
| Type of gastric contents | The type of gastric contents is assessed using ultrasonography. | Before the induction of anesthesia |
Impact of Oral Phosphorus Supplements on the 6-month Change in FGF23 Levels in Anorexic Adolescents Suffering From Undernutrition.

Study Overview
=================
Brief Summary
-----------------
Fibroblast growth factor 23 (FGF23) is a recently discovered phosphaturic hormone produced by osteocytes. It is involved in phosphate-calcium metabolism (via its phosphaturic action and inhibition of 1,25-OH vitamin D). There are no published studies on the role of FGF23 in undernourished anorexic adolescents taking oral phosphorus supplements.

Official Title
-----------------
Impact of Oral Phosphorus Supplements on the 6-month Change in FGF23 Levels in Anorexic Adolescents Suffering From Undernutrition.

Conditions
-----------------
Malnutrition

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Adolescents aged from 11 to 17 Follow-up or hospitalisation for anorexia Overt undernutrition (clinical signs of undernutrition, body mass index and the Waterlow index) Social security coverage Exclusion Criteria: Known pre-existing renal disorders Known constitutional disorders of phosphate-calcium metabolism Adult patients, legal guardianship, incarceration

Ages Eligible for Study
-----------------
Minimum Age: 11 Years
Maximum Age: 17 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| anorexic<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| FGF23 | Change in the FGF23 level (U/ml) with regard to the exogenous phosphorus intake (doses of Phosphoneuros®, expressed in mg/kg/day) | at inclusion and then once a month for 6 months. | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
phosphorus supplementation, FGF23, anorexic, adolescents, undernutrition
Translation, Cross-cultural Adaptation and Validation of the MGQOL-15-F

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to translate and culturally adapt the MGQOL-15 (health-related quality of life scale for myasthenia gravis) for use with French-speaking patients in France and to evaluate its psychometric properties to ensure reliability and validity.

Detailed Description
-----------------
It is a translation and validation of a quality of life scale. Step 1: Translation and cultural adaptation (Forward and back translation, committee review, pre-testing with 10 patients for content and face validity). Step 2 : Psychometric testing : Test-retest with a 2 day interval, correlation with clinical scores - the Myasthenic Muscle Score and the (MG-ADL) score and with a global quality of life score (WHOQOL-BREF).

Official Title
-----------------
Translation, Cross-cultural Adaptation and Validation of the MGQOL-15-F

Conditions
-----------------
Myasthenia Gravis

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Auto-immune myasthenia gravis Age ≥ 18 years old Clinical Classification (MGFA) I-IV French speaking Exclusion Criteria: cognitive or visual impairment which would limit the capacity to fill out the MGQOL-15-F

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Perceived quality of life measured via the MGQOL-15-F (French version of the MGQOL-15), a myasthenia-specific quality of life auto-questionnaire |  | 3 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Global quality of life evaluated via the WHOQOL-BREF scale |  | 1 day | 
| Clinical evaluation : Myasthenic Muscle Score |  | 1 day | 
| Disease severity assessed via the Myasthenic Muscle Score |  | 1 day | 
| Impact of symptoms on daily activities and daily life using the MG-ADL score |  | 1day | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Myasthenia gravis, Quality of life
Practices Made by Patients to Avoid Insulin Injection Pain

Study Overview
=================
Brief Summary
-----------------
Abstract Objective: This study was conducted to determine the knowledge levels of DM patients about the disease and insulin use, and their practices to avoid insulin injection pain. Methods: Data were collected from 399 patients who administered insulin injections in the study. Patient identification form, disease and treatment compliance form, Morisky-8 Treatment Adherence Scale (MMAS-8), and Visual Analog Scale were used for data collection. The data were collected by the same researcher by face-to-face interview technique.

Detailed Description
-----------------
The face-to-face interview technique was applied to all patients who met the inclusion criteria and accepted to participate in the study, in the waiting area of the internal medicine outpatient clinic. Data were collected by the same researcher. Questionnaire forms were filled in the form of questions and answers in 10-15 minutes.

Official Title
-----------------
AVOIDING PAIN CAUSED BY INSULIN INJECTION Patients Using Insulin With Diabetes Seek For Painless Injection

Conditions
-----------------
Diabetes Mellitus

Intervention / Treatment
-----------------
* Other: filling out a survey


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients between the ages of 18-65, diagnosed with diabetes mellitus at least 1 year ago, injecting themselves with insulin. Exclusion Criteria: Having no communication problems, and having no mental illness were included in the study.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: filling out a survey|This research is a descriptive study|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Completing the surveys | Completion of all questionnaires by patients | 7 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Insuline injection pain, lipohypertrophy, nursing care
Impact of Music Therapy on Anxiety in Patients With Cancer Undergoing Simulation for Radiation Therapy

Study Overview
=================
Brief Summary
-----------------
This study looks at the effects of a protocolized music therapy intervention on state anxiety for patients with cancer undergoing simulation for radiation therapy. Simulation, which is an imaging and diagnostic procedure, has been identified as producing significantly high levels of anxiety in many cancer patients.

Official Title
-----------------
The Impact of Music Therapy on Anxiety in Patients Newly Diagnosed With Cancer & Undergoing Simulation for Radiation Therapy

Conditions
-----------------
Anxiety and Distress

Intervention / Treatment
-----------------
* Other: music therapy


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Newly diagnosed patients with breast cancer, and newly diagnosed patients with head and neck cancer. 18 or over. Fluent in English. Exclusion Criteria: Under 18 years. Pre-existing anxiety disorders.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: music therapy<br>pt received a protocolized music therapy intervention that included altered state induction, music driven guided visualiztion, and psychoeducation on relaxation techniques to be used during simulation for radiation therapy. Prescribed pre-recorded music program provided to be used during simulation. | Other: music therapy<br> <br> |
| No Intervention: control<br>no intervention | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Reduction in state anxiety | pt received a protocolized music therapy intervention that included altered state induction, music driven guided visualiztion, and psychoeducation on relaxation techniques to be used during simulation for radiation therapy. Prescribed pre-recorded music program provided to be used during simulation. | 20 minutes | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| reduced distress | pt received a protocolized music therapy intervention that included altered state induction, music driven guided visualiztion, and psychoeducation on relaxation techniques to be used during simulation for radiation therapy. Prescribed pre-recorded music program provided to be used during simulation. | 20 minutes |
Ovarian Cancer Risk Estimation in Patients With Pelvic Mass

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to determine whether the Risk of Ovarian Cancer Algorithm (ROMA) is effective in the determination of a woman's risk of cancer when she is scheduled to have surgery to remove a pelvic mass. After Informed Consent is obtained, an Initial Cancer Risk Assessment will be made. A blood sample will be collected within 30 days of the surgical procedure. Results of the surgical procedure will be collected and analyzed against the CA125 and HE4 results used in the calculation of the ROMA.

Official Title
-----------------
Evaluation of CA125 and HE4 Assays to Estimate the Risk of Ovarian Cancer in Patients Presenting to a General Surgeon or Obstetrician/Gynecologist With an Adnexal Mass

Conditions
-----------------
Adnexal Mass, Ovarian Cancer

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Female, age ≥ 18 years Adnexal mass present documented by imaging Scheduled to undergo surgery based on a finding of adnexal mass (defined as a simple, complex or a solid ovarian cyst/or any mass in pelvis) Able to understand and willing to provide Informed Consent Exclusion Criteria: Previous history of ovarian cancer Previous history of bilateral oophorectomy Currently known to be pregnant Unable to provide informed consent

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 1. A statistically higher number of cancer patients are correctly assigned by the combination of Initial Cancer Risk assessment and positive ROMA test result than by Initial Cancer Risk assessment alone |  | Blood draw within 30 days of surgery | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
pelvic mass, ovarian cancer, adnexal mass, CA125, HE4
Role of Cord Blood Hormones and Epinephrine in the Development of Transient Tachypnea of the Newborn

Study Overview
=================
Brief Summary
-----------------
In this prospective, cross-sectional study, the aim was to investigate the possible role of cord stress hormones; adrenocorticotropic hormone (ACTH), cortisol, epinephrine, sT3, sT4, and thyroid-stimulating hormone (TSH) in the development of Transient Tachypnea of the Newborn (TTN), via their modulatory effect on epithelial sodium channels and Na-K-ATPase.

Conditions
-----------------
Wet Lung

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Gestation age > 34 weeks C/S delivered infants Parental consent form signed Exclusion Criteria: Gestation age < 34 weeks Maternal conditions that compromised fetal well-being (hypertensive disorder, diabetes, chorioamnionitis) Intrauterine growth retardation Congenital malformations Absence of parental consent

Ages Eligible for Study
-----------------
Minimum Age: 34 Weeks
Maximum Age: 40 Weeks

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| C/S delivered, wet lung<br> | |
| C/S delivered, healthy infants<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Stress response at birth, as demonstrated by cord cortisol, adrenocorticotropic hormone, epinephrine, fT3, fT4, and thyroid-stimulating hormone in late preterm and term neonates developing transient tachypnea of the newborn. | At birth cord blood samples and perinatal data were collected from ceseraen deliveries of late preterm and term infants. Cord stress hormones of the infants with the diagnosis of TTN and gestational age matched controls were analyzed. | postnatal first 24 hours | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Fetal lung fluid, Pulmonary adaptation, Transient tachypnea of the newborn, Epinephrine, Stress hormones
Perioperative Effect of Atenolol on Cytokine Profiles

Study Overview
=================
Brief Summary
-----------------
Studies have shown that beta-blockers such as atenolol when given in the perioperative period reduce morbidity and mortality. One study showed that atenolol given just during the surgery period, seemed to improve outcomes up to 2 years later. This is hard to explain since beta-blockers act on the body by blocking the effects of adrenalin and thereby lowering heart rate and blood pressure. This study is designed to find out if perioperative atenolol might exert its long term effects through an anti-inflammatory mechanism rather than by lowering heart rate and blood pressure. It is known that inflammation increases after surgery as part of the healing process. However, it is also becoming clear that low-grade chronic inflammation can also lead to long term adverse effects.

Official Title
-----------------
The Effect of Perioperative Atenolol on Post-Operative Cytokines

Conditions
-----------------
Surgery

Intervention / Treatment
-----------------
* Drug: atenolol
* Drug: placebo


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: elective abdominal, orthopedic, or gynecologic surgery ability to give informed consent ability to tolerate beta-blocker therapy ability to comply with follow-up requirements Exclusion Criteria: currently receiving beta-blocker therapy EKG documented 2nd or 3rd degree heart block EKG documented sinus bradycardia Serum creatinine > 2.0 current treatment asthma history of rheumatoid arthritis history of Crohn's disease history of lupus history of inflammatory cancer

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Placebo Comparator: placebo<br> | Drug: placebo<br> <br> |
| Experimental: atenolol<br> | Drug: atenolol<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative levels of IL-6 and C-Reactive protein |  | 6 hrs, 48 hrs, 6 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| IL-10, TNF-α |  | 6 hrs, 48 hrs, 6 weeks | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
perioperative, beta-blockers, inflammation, outcomes
Shanghai ST-segment Elevation Myocardial Infarction Cohort

Study Overview
=================
Brief Summary
-----------------
ST-segment elevation myocardial infarction(STEMI) remains a major cause of morbidity and mortality worldwide, despite of the early reperfusion therapy, including fibrinolysis, primary percutaneous coronary intervention (PCI),and standardized medical treatment.To improve the prognosis of STEMI patients, the management in their hospitalization should be optimized, including improvements in risk stratification, more widespread use of an invasive strategy, implementation of care delivery systems prioritising immediate revascularisation through PCI (or fibrinolysis), advances in antiplatelet agents and anticoagulants, and greater use of secondary prevention strategies such as lipid-lowering therapy. This study aims to standardized the management of STEMI patients and improve the prognosis of the STEMI patients.

Detailed Description
-----------------
This study is a prospective cohort study. It aims to standardized the management of STEMI patients and improve the prognosis of the STEMI patients.

Official Title
-----------------
A Prospective Multicentre Cohort Study of Acute ST-segment Elevation Myocardial Infarction

Conditions
-----------------
ST Elevation Myocardial Infarction

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: ST elevation myocardial infarction Coronary angiography and percutaneous coronary intervention within 12 hours of symptom onset Capable and willing to provide informed conset and capable of completing study visits Exclusion Criteria: Cardiovascular shock at admission Severe physical disability Active malignant tumors Active autoimmune diseases

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| MACE | Major adverse cardiovascular events(MACE) in one year follow-up | 0-1 year | 
| Left Ventricular Function | Left ventricular end diastolic volume(LVEDV),Left ventricular end systolic volume(LVESE),Left ventricular ejection fraction(LVEF) changes within one year follow-up | 1 month, 6month and 1 year | 
| Coronary angiography | The pathological changes in culprit vessels in 1 year | 1 year | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Acute Myocardial Infarction, Cardiac Remodelling, Heart Failure