Weight Outlooks by Restriction of Diet and Sleep

Study Overview
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Brief Summary
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The purpose of this study is to examine whether chronic moderate sleep restriction effects the amount of body fat and lean mass loss, and calorie expenditure, in individuals who are participating in a dietary weight loss program.

Detailed Description
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Participants will be randomly assigned to an 8-week program of either restricted diet alone, or restricted diet with restricted sleep for 5 days a week. The total expected duration of participation is approximately 3 months.

Official Title
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Weight Outlooks by Restriction of Diet and Sleep

Conditions
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Weight

Intervention / Treatment
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* Behavioral: Calorie restriction only
* Behavioral: Sleep & calorie restriction


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: age between 35-55 years, BMI between 30-35 kg/meters squared, total sleep time between 6.5-8 hours Exclusion Criteria: work requiring changing schedule, use of sleep aids or sleep medication

Ages Eligible for Study
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Minimum Age: 35 Years
Maximum Age: 55 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Calorie Restriction Only<br>Participants in this group will be decreasing their caloric intake to approximately 95% of their resting metabolic rate. We will provide one meal for 4 days of the week, and participants will be required to keep an accurate dietary record of all food and drink. Participants assigned to this group will be instructed to keep a fixed sleep schedule based on their own sleep/napping habits. | Behavioral: Calorie restriction only<br>* Participants randomly assigned to this group will be instructed to reduce their daily energy intake to 95% of their resting metabolic rate.<br>|
| Experimental: Sleep & Calorie Restriction<br>Participants in this group will decrease their caloric intake to approximately 95% of their resting metabolic rate in addition to reducing their total time in bed by 90 minutes 5 days a week. | Behavioral: Sleep & calorie restriction<br>* Participants randomly assigned to this group will be instructed to reduce their total time in bed by 90 minutes 5 days a week, in addition to restricting their dietary intake to approximately 95% of their resting metabolic rate.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| body composition measured via DXA scans | Body composition will be measured via DXA scans prior to intervention and post intervention to compare losses in lean body mass and fat mass. | 4 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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body composition, anthropometry