Effect of Extraction Vs Non-extraction Orthodontic Treatment on Vertical Facial Dimension

Study Overview
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Brief Summary
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The aim of the current clinical trial was to evaluate the effects of premolar extractions compared with non-extraction orthodontic treatment on the skeletal vertical dimension of the face. The null-hypothesis is that there is no difference in post-treatment skeletal vertical characteristics of normodivergent and hyperdivergent patients treated orthodontically with first premolar extractions compared with patients treated in non-extraction manner.

Detailed Description
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The current protocol will be submitted for partial fulfillment of the PhD requirements in Faculty of Dentistry, Cairo University. The trial will be conducted in the outpatient clinic of the Orthodontic Department, Faculty of Dentistry, Cairo University. Primary examination and diagnosis of the patients seeking orthodontic treatment will be performed, to select a sample of the trial. then, final diagnosis and planing of each participant will be performed by a trained orthodontists to be sure that all patients fallen with the inclusion criteria. Interventions will be conducted with the same orthodontist, under supervision of orthodontic professors in the Orthodontic department, Cairo University.

Official Title
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Effect of Extraction Versus Non-extraction Orthodontic Treatment on Vertical Facial Dimension: A Non-Randomized Clinical Trial

Conditions
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Malocclusion, Long Face Syndrome, Crowding, Tooth

Intervention / Treatment
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* Device: Extraction orthodontic treatment
* Device: Non-extraction orthodontic treatment


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Normodivergent and hyperdivergent patients Cases with moderate crowding. Borderline cases which could be treated with extraction or non-extraction strategies Exclusion Criteria: Hypodivergent patients. Cases with extremely sever crowding. Patients with high caries index or periodontal problems. Patients with systemic diseases, or syndromic conditions.

Ages Eligible for Study
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Minimum Age: 11 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: -Interventions Intervention Group (I) Extraction treatment group. Bonding all cases will be performed by the principal investigator, then premolars extraction will be done, then installing the 1st alignment wire. Comparator group (C): Non-extraction group. Same orthodontist will bond all the cases and install the 1st alignment wire.
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Extraction orthodontic treatment<br>orthodontic treatment with teeth extraction | Device: Extraction orthodontic treatment<br>* orthodontic treatment with teeth extraction<br>* Other names: Braces with teeth extraction;|
| Active Comparator: Non-extraction orthodontic treatment<br>non-extraction orthodontic treatment | Device: Non-extraction orthodontic treatment<br>* Non-extraction orthodontic treatment<br>* Other names: Braces with no extraction of teeth;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes in Vertical Dimension (VD) | Vertical dimension of the face will be assessed by measuring a distances in millimeters between vertical points as ANS-Me (lower facial height), also it will be measured form angles in a degrees as angle SN/MP | after 1year. Changes will be measured before the start of trial and at the end of space closing stage, which anticipated to be within 12 months of intervention | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes in Overbite | Distances in millimeters will be measure directly in patient mouth by using caliper it will be measured in millimeters. | 1 year . Changes will be measured before the start of trial and at the end of space closing stage, which anticipated to be within 12 months of intervention | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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orthodontics, vertical dimension, premolars extraction, long face