Which is Better Between Single Chest Tube and Multiple Tubes Drainage in Primary Spontaneous Pneumothorax

Study Overview
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Brief Summary
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There was no evidence that the number of chest tube do effect to the recurrence of pneumothorax, which placed after thoracoscopic wedge resection together with mechanical pleurodesis.This study evaluates the efficacy of single chest tube versus multiple tubes drainage in spontaneous pneumothorax after VATS bullectomy and pleurodesis. After routine procedure the participants will randomized to either placed single chest tube or multiple chest tubes

Detailed Description
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Primary spontaneous pneumothorax (PSP) occurs after the rupture of small bullae or a subpleural bleb in otherwise normal lungs. The indications for surgical treatment include persistent air leak after intercostal tube drainage, recurrent PSP, and contralateral PSP. The video-assisted thoracoscopic surgery (VATS) approach probably represents the treatment of choice for PSP. The presence of a residual pleural space after surgery may be a factor associated with increased risk of recurrence. One possible hypothesis to explain the association between residual pleural space and recurrence of pneumothorax may be the failed pleurodesis due to lack of pleura-pleura apposition. Multiple chest tubes are effective in clinical practice, but there was no convinctive evidence that the number of chest tube do effect to the recurrence of pneumothorax, which placed after thoracoscopic wedge resection together with mechanical pleurodesis. This study evaluates the efficacy of single chest tube versus multiple tubes drainage in spontaneous pneumothorax after VATS bullectomy and pleurodesis.After routine procedure the participants will randomized to either placed multiple chest tubes or single chest tube. The recurrence of the two group and other postoperative clinical parameters will be observed.

Official Title
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Comparison of the Efficacy of Single Tube Versus Multiple Tubes Drainage After Bullectomy and Pleurodesis for Primary Spontaneous Pneumothorax

Conditions
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Primary Spontaneous Pneumothorax

Intervention / Treatment
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* Procedure: single chest tube drainage


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Diagnosed by chest radiograph or CT as primary spontaneous pneumothorax Underwent bullectomy and pleurodesis Postoperative indwelling chest tubes Exclusion Criteria: Secondary pneumothorax, traumatic pneumothorax and iatrogenic pneumothorax Previous surgery history People with severe comorbidities

Ages Eligible for Study
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Minimum Age: 16 Years
Maximum Age: 40 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: single chest tube group<br> | Procedure: single chest tube drainage<br>* place single chest tube after surgery of PSP<br>|
| No Intervention: multiple chest tubes group<br> | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| recurrence | Recurrence of pneumothorax during 2 years follow-up | 2 years after operation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| complications | post-operation complications，such as air leakage | 30days after operation | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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number of chest tube, Bullectomy, Pleurodesis, Primary Spontaneous Pneumothorax