A Retrospective Study on Hospitalized Patients With Community-acquired Pneumonia in China (CAP-China)

Study Overview
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Brief Summary
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The purpose of this study is to evaluate the disease burden of hospitalized patients with CAP and healthcare-associated pneumonia (HCAP) in real life of China .

Detailed Description
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In China, the data about current management of patients hospitalized with CAP in the real-life setting is not available,type of pneumonia, selection of initial antibiotic, time to clinical stability, antibiotic choice anf modification,clinical outcomes and costs remain unclear. In this study, we will collect comprehensive information on CAP and HCAP management patterns to evaluate the disease burden of hospitalized patients with CAP and HCAP in real life of China .to analyze microbiological characteristics,clinical manifestations,antibiotic regimens ,adherences to guidelines and effect on outcome in different groups of patients with CAP (> and = 65 years, different comorbidities ,risk factors) ,to investigate microbiological characteristics,clinical manifestations,antibiotic regimens ,adherences to guidelines and effect on outcome in different groups of disease severity with CAP ,to provide the difference on microbiological characteristics,clinical manifestations,antibiotic regimens ,and outcome between patients with CAP and HCAP ,to understand the current situation of antibiotic regimen ,to evaluate influence of different antibiotic regimens on prognosis.

Official Title
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Management in Real-life of Patients Hospitalized With Community-acquired Pneumonia in China

Conditions
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Community Acquired Pneumonia

Intervention / Treatment
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* Other: other


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients > or = 14 years of age Patient meets the criteria of community acquired pneumonia Patient meets the criteria of healthcare-associated pneumonia Exclusion Criteria: Patients <14 years of age Patient meets the criteria of hospital acquired pneumonia Known active tuberculosis or current treatment for tuberculosis Non-infectious pulmonary diseases HIV positive

Ages Eligible for Study
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Minimum Age: 14 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: other|retrospective cohort study|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| treatment failure at 72h after initiation of antibiotics | treatment failure was defined as a change of antibiotics due to worsening signs or symptoms associated with pneumonia | Time from the first dose use of antibiotics to 72 hours | 
| in-hospital treatment failure due to multiple causes | 1)death in hospital;2)change of antibiotics due to worsening signs or symptoms of infection, 3) recurrence, defined as signs or symptoms of infection after completion of therapy requiring re-initiation of antibiotics | Time from date of admission to discharge up to 1 week | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Duration of intravenous antimicrobial therapy | Time from the first dose of intravenous antibiotics to date of stop of intravenous antibiotics ,participants will be followed for the duration of hospital stay | 2 weeks | 
| Hospital length of stay | Patients will be asked about hospitalization, date, Patients will be asked about hospitalization, date, participants will be asked about the time of admission and discharge | 2 weeks | 
| in-hospital mortality | Time from date of admission to date of discharge,participants will be followed for the duration of hospital stay | 2 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Community Acquired Pneumonia, health care associated pneumonia