Radiofrequency Neurotomy In Relieving Chronic Knee Pain

Study Overview
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Brief Summary
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Osteoarthritis (OA) affects aged above 45 years. RF has been used for several painful conditions. There have been a few attempts to use RF current for the treatment of painful conditions of joints of the extremities. It was also used for the treatment of painful conditions of the hip joint.

Detailed Description
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Osteoarthritis (OA) is commonest chronic arthritis affecting patients usually aged above 45 years. OA decreased health-related quality of life and increased economic costs. Radiofrequency (RF), was used for the treatment of chronic pain unresponsive to conservative therapies. RF has been used for several painful conditions. There have been a few attempts to use RF current for the treatment of painful conditions of joints of the extremities. It was also used for the treatment of painful conditions of the hip joint.

Official Title
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Fluoroscopic Guided Radiofrequency of Genicular Nerves for Pain Alleviation in Chronic Knee Osteoarthritis : A Single-blind Randomized Controlled Trial.

Conditions
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Osteo Arthritis Knee, Pain, Chronic

Intervention / Treatment
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* Procedure: radiofrequency
* Drug: Paracetamol (conventional)
* Drug: Ketorolac Tromethamine (conventional)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: chronic arthritis according to the American College of Rheumatology criteria diagnosed radiologically patients in stage 3 and 4, according to the Kellgren-Lawrence classification Exclusion Criteria: other causes of pain such as radiculopathy, neurological disorders, or intermittent claudication. patients receive intraarticular steroid or hyaluronic acids during previous three months. patients did previous knee surgery. Patients with general contraindication to the application of invasive intervention such as hemorrhage, coagulation disorder, systemic infection or local infection. patients with other connective tissue disease affecting the knee. And 6-psychiatric disorders.

Ages Eligible for Study
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Minimum Age: 30 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: radiofrequency group<br>radiofrequency was done in the three genicular nerves upper medial and upper lateral and lower medial | Procedure: radiofrequency<br>* radiofrequency done in the three genicular nerves upper medial and upper lateral and lower medial<br>|
| Active Comparator: conventional group<br>the patients received conventional paracetamol and non steroidal antiinflammatory | Drug: Paracetamol (conventional)<br> <br> Drug: Ketorolac Tromethamine (conventional)<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| pain assessment by VAS scale | assessing pain by VAS scale | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| patient satisfaction by Likert scale | Likert scale to assess patients satisfaction | 6 months | 
| patient disability by Western Ontario McMaster Universities OA index | Western Ontario McMaster Universities OA index to assess disability | 6 months |