Retrospective Study of Keloid Disorder

Study Overview
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Brief Summary
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Purpose of this retrospective study is to review and analyze the information and data that has been already been generated during the course of routine practice of medicine by the investigators from 2007 up until Sept 1, 2016 from keloid patients who have sought medical care or medical advice for their keloid disorder.

Detailed Description
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To retrospectively review and analyze clinical data that has already been collected from keloid patients including photographs taken of keloid lesions during routine practice of medicine by the investigators 1) To better understand natural history of keloid disorder (KD), 2)To determine the ethnic incidence and prevalence of keloid, 3) To determine the rate of familial keloids, 4) To determine response to different treatment modalities, 5) To determine risk factors for development and worsening of keloid lesions.

Official Title
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Retrospective Study of Keloid Disorder

Conditions
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Keloid

Intervention / Treatment
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* Procedure: History of prior Surgery
* Radiation: History of Radiation Therapy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All patients must have at least one keloid lesion. Availability of photographic documentation of keloid lesion(s). Exclusion Criteria: Lack of photographic documentation of keloid lesion(s) Lack of demographic data
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients with Ear Keloids<br>Records of Patients with Ear Keloids will be reviewed. Data and photographs will be analysed. | Procedure: History of prior Surgery<br>* History of prior Surgery will be reviewed<br>* Other names: Surgery;Radiation: History of Radiation Therapy<br>* History of prior radiation therapy will be reviewed<br>* Other names: Radiation Therapy;|
| Patients with Neck Keloids<br>Records of Patients with Neck area Keloids will be reviewed. Data and photographs will be analysed. | Procedure: History of prior Surgery<br>* History of prior Surgery will be reviewed<br>* Other names: Surgery;Radiation: History of Radiation Therapy<br>* History of prior radiation therapy will be reviewed<br>* Other names: Radiation Therapy;|
| Patients with Scalp Keloids<br>Records of Patients with Scalp Keloids will be reviewed. Data and photographs will be analysed. | Procedure: History of prior Surgery<br>* History of prior Surgery will be reviewed<br>* Other names: Surgery;Radiation: History of Radiation Therapy<br>* History of prior radiation therapy will be reviewed<br>* Other names: Radiation Therapy;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rate of development of massive, semi-massive and large Keloids | Keloid Recurrence after surgery is a real-world outcome, one that takes time to develop. Study will intend to explore the long term rate of keloid recurrence after surgery. This rate will be reported as percentage of patients who undergo surgery and end up with developing a massive, semi-massive or large recurrent keloid | 1-5 years after surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rate of poor aesthetic outcome after ear surgery | Surgical intervention often results in loss of ear tissue and poor aesthetic outcome. Although fully expected, the actual rates of this outcome is unknown. Study intends to report the actual rate of disfigurement and poor aesthetic outcome after ear surgery for removal of keloid lesions. | 1-5 years after surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Keloid