German Cardiac Arrest Registry

Study Overview
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Brief Summary
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In Germany, 70.000 to 100.000 patients suffer from out-of-hospital cardiac arrest (OHCA) every year. More than half of these are due to cardiac causes. Despite the medical progress over the last decades, rates of survival with good neurological outcome remain low. For many below-mentioned issues, no adequate evidence from randomized trials is available. Therefore, a systematic and standardized recording of the pre-clinical, clinical and post-clinical treatment course and of the clinical outcomes of OHCA patients is essential to improve patient care. Aim of the German Cardiac Arrest Registry (G-CAR) is to achieve a better understanding of the disease entity, leading to an optimized treatment of OHCA patients. The recorded data include information on demographic and psychosocial aspects, course of the disease, clinical, laboratory and other examinations as well as treatment modalities in patients with OHCA due to a cardiac cause.

Official Title
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German Cardiac Arrest Registry

Conditions
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Out-of-hospital Cardiac Arrest

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients with out-of-hospital cardiac arrest with assumed cardiovascular cause Exclusion Criteria: rejection of register participation by patient or legal representative

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| In hospital mortality |  | until discharge, an average of 2 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Length of ICU stay |  | until discharge, an average of 2 weeks | 
| Length of hospital stay |  | until discharge, an average of 2 weeks | 
| Mortality |  | Day 30 | 
| Mortality |  | Month 6 | 
| European Quality of Life 5 Dimensions 5 Level Version (EQ-5D) | five levels in each dimension are worded as (1) 'not /no problems', (2) 'slight problems', (3) 'moderate problems', (4) 'severe problems', and (5) 'unable to' | Month 6 | 
| Post Traumatic Stress Syndrome | PTSS-14 | Month 6 | 
| Reintegration | Reintegration to Normal Living Index | Month 6 | 
| Hospital Anxiety and Depression Scale (HADS) | score 0-21; higher value show more severe depression | Month 6 | 
| Mini Montreal Cognitive Assessment (MoCA) | score 0-15; 11 or higher is normal, 10 or less indicate cognitive dysfunction | Month 6 | 
| Mini Montreal Cognitive Assessment (MoCA) | score 0-15; 11 or higher is normal, 10 or less indicate cognitive dysfunction | Month 12 | 
| Mortality |  | Month 12 | 
| European Quality of Life 5 Dimensions 5 Level Version (EQ-5D) | five levels in each dimension are worded as (1) 'not /no problems', (2) 'slight problems', (3) 'moderate problems', (4) 'severe problems', and (5) 'unable to' | Month 12 | 
| Post Traumatic Stress Syndrome (PTSS-14) | scor 14-98; higher value indicate more post traumatic stress | Month 12 | 
| Reintegration | Reintegration to Normal Living Index | Month 12 | 
| Hospital Anxiety and Depression Scale (HADS) | score 0-21; higher value indicate more severe depression | Month 12 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Out-of-hospital Cardiac Arrest, OHCA, resuscitation, cardiac arrest center, acute care medicine, intensive care, post-resuscitation care