Effect of Inspiratory Muscle Training During PR on Dyspnoea and Exercise Tolerance in COPD Patients

Study Overview
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Brief Summary
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Chronic obstructive pulmonary disease is a respiratory disease that results in progressive airflow limitation and respiratory distress. The benefit of inspiratory muscle training (IMT) combined with a pulmonary rehabilitation programme is uncertain. The investigators aimed to demonstrate that, in patients with obstructive pulmonary disease, IMT performed during a PRP is associated with an improvement of dyspnoea and exercise tolerance.

Detailed Description
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The purpose of this study is to evaluate the effect of the inspiratory muscle training (with incremental load every two weeks in two months) performed during pulmonary rehabilitation on dyspnoea, 6 minutes walk test and quality of life using the St George's respiratory questionnaire (SGRQ) in COPD patients.

Official Title
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Effect of Inspiratory Muscle Training During PR on Dyspnoea and Exercise Tolerance in Chronic Obstructive (COPD)

Conditions
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Chronic Obstructive Pulmonary Disease

Intervention / Treatment
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* Other: Pulmonary rehabilitation+IMT
* Other: Pulmonary rehabilitation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Were COPD diagnosed by pulmonary function testing Clinically stable Abscence of other obstructive diseases Signed written consert Exclusion Criteria: Were previous pneumonectomy or lobectomy in the past 6 months spontaneous risk of pneumothorax or rib fracture Incapacity to follow a standard rehabilitation programme (locomotor deficits, acute cardiac failure and acute exacerbation of COPD at the beginning of the programme) The absence of written informed consent.

Ages Eligible for Study
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Minimum Age: 45 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: IMT goup<br>Inspiratory muscle training + aerobic exercice | Other: Pulmonary rehabilitation+IMT<br>* The experimental group receives inspiratory muscle training and aerobic exercise.<br>|
| Active Comparator: Control group<br>aerobic exercice | Other: Pulmonary rehabilitation<br>* The Active Comparator group received only aerobic exercise.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Dyspnoea | The dyspnoea were measured before and after the 6 minutes walk test | Baseline, After 2 months | 
| Inspiratory muscle strength | The inspiratory muscle strength were measured by maximal inspiratory pressure test | Baseline, After 2 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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COPD, IMT, 6MWT, Dyspoea, SGRQ