Prevalence of COVID-19 Infection Among HCW in a French University Hospital

Study Overview
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Brief Summary
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The objective of this study is to determine the prevalence of SARS-Cov2 infection among health care workers exposed of Lille University Hospital, to describe its evolution during the epidemic taking into account the influence of occupational and environmental exposure determinants.

Official Title
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Prevalence of SARS-Cov2 Infection Among HCW in Lille University Hospital

Conditions
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Sars-CoV2

Intervention / Treatment
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* Other: self-administered questionnaire
* Diagnostic Test: SARS-Cov2 testing


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: - Health Care workers with or without symptoms suggestive of a COVID-19 infection Exclusion Criteria: HCW working off-site at the CHU de Lille HCW on sick leave. HCW outside the Lille University Hospital temporarily coming as reinforcements in the context of the epidemic.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| High-risk<br>staff working in a unit specifically for patients infected or suspected of being infected with SARS-Cov2 | Other: self-administered questionnaire<br>* Every weeks during 2 months, clinical and occupational questionnaire are performed among a cohort of HCW exposed to covid occupational exposure<br>* Other names: a specifically designed self-administered questionnaire;Diagnostic Test: SARS-Cov2 testing<br>* Every weeks during 2 month, SARS-Cov2 RT-PCR, serological testing are performed among a cohort of HCW exposed to covid occupational exposure<br>|
| Medium- risk<br>staff working in a unit that can accommodate patients infected or suspected of being infected with SARS-Cov2, i.e., all care services that do not fall into the high-risk group. | Other: self-administered questionnaire<br>* Every weeks during 2 months, clinical and occupational questionnaire are performed among a cohort of HCW exposed to covid occupational exposure<br>* Other names: a specifically designed self-administered questionnaire;Diagnostic Test: SARS-Cov2 testing<br>* Every weeks during 2 month, SARS-Cov2 RT-PCR, serological testing are performed among a cohort of HCW exposed to covid occupational exposure<br>|
| Low-risk<br>off-patient staff | Other: self-administered questionnaire<br>* Every weeks during 2 months, clinical and occupational questionnaire are performed among a cohort of HCW exposed to covid occupational exposure<br>* Other names: a specifically designed self-administered questionnaire;Diagnostic Test: SARS-Cov2 testing<br>* Every weeks during 2 month, SARS-Cov2 RT-PCR, serological testing are performed among a cohort of HCW exposed to covid occupational exposure<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the prevalence of SARS- Cov2 infection Health Care Worker with or without symptoms suggestive of a COVID-19 infection |  | at 2 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the prevalence of SARS- Cov2 infection Health Care Worker with or without symptoms suggestive of a COVID-19 infection |  | once week during 2 months | 
| Occupational exposures associated with the SARS-Cov2 infection |  | once week during 2 months | 
| Environmental exposures associated with the SARS-Cov2 infection |  | once week during 2 months | 
| immunologic status of health Care Worker |  | once week during 2 months | 
| inflammatory biomarkers status of Health Care Worker |  | once week during 2 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Prevalence, Health Care Workers, occupational exposure, environmental exposure, serological testing, RT-PCR