Post-exercise Food Intake Regulation in a Hot Environment

Study Overview
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Brief Summary
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The potential of physical activity and other non-medicinal methods for the care and prevention of metabolic and cardiovascular disorders has been insufficiently used. There is a potential influence of environmental heat in energetic balance regulation. However, the existing knowledge is insufficient to optimize physical activity programs based on the impact of exercise on energy intake regulation in hot climates. The aim of the present study is to define the major physiological determinants of short-term food intake regulation in young active and healthy men, when exposed to different levels of metabolic activity and environmental temperatures. We will thus explore the biological mechanisms related to post-exercise relative energy intake. Post-rest and post-exercise energetic compensation will be analysed in these different environmental conditions, with a special focus on the effect of the birth weight. This study should open interesting ways to define adequate nutritional and exercising programs in hot environments.

Official Title
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Post-exercise Food Intake Regulation in a Hot Environment

Conditions
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Healthy and Physically Active Young Men

Intervention / Treatment
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* Behavioral: Rest
* Behavioral: Exercise


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: healthy and physically active men aged 18-30 years Exclusion Criteria: any physical or medical problem liable to limit the subjects' ability to perform the exercise testing in safe conditions, ear troubles

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 30 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Hot environment<br>Subjects will perform the intervention in a hot environment (33°C) | Behavioral: Rest<br> <br> Behavioral: Exercise<br> <br> |
| Sham Comparator: Neutral environment<br>Subjects will perform the intervention in a neutral environment (22°C) | Behavioral: Rest<br> <br> Behavioral: Exercise<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Relative post-exercise and post-rest energy intake |  | 11 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Appetite hormones | insulin, CCK, leptin, ghrelin, pancreatic peptide | 13 months | 
| Heart rate variability |  | 11 months | 
| Tympanic temperature |  | 11 months | 
| Peak exercise capacity |  | 11 months | 
| Appetite visual analogic scale |  | 11 months | 
| metabolic markers | glucose, lipid profile, cortisol | 13 months | 
| vascular biomarkers | usCRP, inflammatory markers, hemorheological markers | 13 months | 
| comfort visual scale |  | 11 months |