Impact of Switching to Non-Menthol Cigarettes Among Smokers

Study Overview
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Brief Summary
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This pilot study will investigate within-person changes in smoking behavior when current adult smokers are systematically switched from smoking menthol cigarettes to non-menthol cigarettes.

Detailed Description
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The goals of this project include evaluating the feasibility of a cigarette switching paradigm to examine how switching adult smokers from menthol to non-menthol cigarettes impacts smoking behavior and satisfaction. Smoking behavior will be measured by self-reported total number of cigarettes and time to first cigarette in the morning, assessed during the period of menthol smoking (week 1) and again after switching to non-menthol cigarettes (weeks 2, 3). Smoking satisfaction will be measured by self-reported ratings of the cigarettes, assessed during the period of menthol smoking (week 1) and again after switching to non-menthol cigarettes (weeks 2, 3).

Official Title
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Impact of Switching to Non-Menthol Cigarettes Among Smokers

Conditions
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Tobacco Use

Intervention / Treatment
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* Other: Cigarette Brand Switching


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 18 or older Able to read English Cigarette smoker Exclusion Criteria: Seeking smoking cessation treatment Serious psychiatric or medical condition Use of other drugs Unable or unwilling to complete study protocol

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Intervention Model: Single Group Assignment
Interventional Model Description: Within-subject design comparing smoking behavior when using menthol vs. non-menthol cigarettes
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Cigarette Brand Switching<br>Adult smokers will be switched from using menthol cigarettes to non-menthol cigarettes | Other: Cigarette Brand Switching<br>* Adult smokers will be switched from smoking menthol cigarettes to non-menthol cigarettes for a period of two weeks<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Total Number of Cigarettes Smoked | Change in self-reported total number of cigarettes smoked per day after switching to non-menthol cigarettes | Menthol smoking (Week 2), Non-menthol smoking (Week 4) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Nicotine Dependence | Self-reported subjective ratings of nicotine dependence after switching to non-menthol cigarettes (measured as change in Wisconsin Inventory of Smoking Dependence Motives (WISDM) total dependence scores). Total range 11-77 with higher scores indicating greater nicotine dependence. | Week 4 (non-menthol) | 
| Quitting Interest | Self-reported subjective motivation/interest in quitting smoking after switching to non-menthol cigarettes. Measured by the item how important is quitting smoking to you? from 1 not at all to 10 extremely. | Week 4 (non-menthol) |