Complex Decongestive Applications in Patients With Lipedema

Study Overview
=================
Brief Summary
-----------------
Lipedema is a rare condition which almost exclusively affects women. The disease is characterized with bilateral, symmetric abnormal accumulation of subcutaneous fat and is often mistaken for simple obesity. In most patients, the hips, buttocks, thighs, knees, and lower legs are affected. Upper extremity involvement has been reported to be present in 80% patients. The hands and feet are never affected. The accumulation of subcutaneous fat and edema results in tenderness, sensitivity to touch and pressure and also pain. Patients also tend to bruise easily even after a minimal trauma. It has been reported that the complaint of pain increases with aging.There is no known cure for lipedema. However, conservative treatment with physiotherapy, manual lymph drainage and compression, also known as complex decongestive physiotherapy is used worldwide as a standard treatment regimen . The aim of this study is to investigate the effect of complex decongestive applications on lower extremity limb circumference and volume in patients with lipedema.

Detailed Description
-----------------
All participants included in the study were included in a treatment protocol consisting of complex decongestive physiotherapy Each patient received; 45 minutes of manual lymph drainage on both lower extremities, Moisturisation of the lower extremities, Bandage application Alongside this routine, the patients were advised to exercise (walk) regularly every day. This treatment routine was continued until the patients were discharged from the clinic.

Official Title
-----------------
The Effect of Complex Decongestive Applications on Lower Extremity Limb Volume in Patients With Lipedema

Conditions
-----------------
Lipedema

Intervention / Treatment
-----------------
* Other: Manual Lymph Drainage
* Other: Bandaging


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Being willing to participate in the study Being 18-65 years old Having a diagnosis of lower extremity lipedema Exclusion Criteria: - Having edematous disease in the lower extremity such as lymphedema or chronic venous insufficiency

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Complex Decongestive physiotherapy<br>All participants included in the study were included in a treatment protocol consisting of Complex Decongestive physiotherapy. | Other: Manual Lymph Drainage<br>* Manual lymph drainage is an effective therapeutic method used in the conservative treatment of lipedema. The application was performed on both lower extremities for 45 minutes.<br>Other: Bandaging<br>* Multilayered compression bandaging techniques have an assisting role in the further reduction of the volume of the limb and enhance the continuous pump mechanism via the active involvement of muscle pumps. All patients received bandages following Manual lymph drainage application.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Limb Volume | In measurement of limb volume, the perometer was used. The device measures limb volume via infrared light and it has been reported to be a quick and reliable method. The device has a square frame which is used to surround the perimeter of the limb. The limb interrupts the emitted infrared beams that would normally be sensed by the light-sensing diodes in the two planes. Thus two perpendicular diameter measurements of the limb for the measured segment are provided. The device estimates the opposite two sides based on an elliptical cross-section. | Change from Baseline limb volume at 6 weeks | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Lipedema, Manual lymph drainage, Complex Decongestive Physiotherapy