A Clinical Observation on Neuropsychology and Electrophysiology in Headache Patinets With Myofascial Trigger Points

Study Overview
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Brief Summary
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To study the clinical characteristics of headache patients with pericranial myofascial trigger points(MTrPs),and to explore the possible pathogenesis of MTrPs,investigators hope to find the possible electrical biomarkers for clinical diagnosis and treatment, and to improve the effect of headache treatment.

Detailed Description
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A series of neuropsychological test scale including Mini-mental State Examination(MMSE),Hamilton Anxiety Rating Scale(HAMA) and Hamilton Depression Rating Scale (HMAD) were evaluated among all patients.The needle pole electromyography (EMG) inspection were practiced on subjects with myofascial trigger points ,for analysing those electrophysiological characteristics.

Official Title
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A Clinical Observation on Neuropsychology and Electrophysiology in Headache Patinets With Myofascial Trigger Points

Conditions
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Myofascial Trigger Points

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Primary headache patients with pericranial myofascial trigger points. Exclusion Criteria: Cranial weeks muscle infection or trauma, medical history, physical examination, laboratory and imaging studies suggest secondary headache patients except cervicalheadache.
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Headache Groub<br>Headache patients with myofascial trigger points. | |
| Healthy Groub<br>No headache or other diseases can cause headaches of healthy people. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Electromyography | The needle pole electromyography (EMG) inspection | 30 minutes | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Hamilton Anxiety Rating Scale(HAMA) | Evaluating Anxiety state: Total score without anxiety symptoms less than 7 ,> 7 points might be anxious, > 14 points must be anxious, > 21 points obvious anxiety, 29 > serious anxiety | 20 minutes | 
| Mini-mental State Examination(MMSE) | Evaluating cognitive State, MMSE boundary between normal and abnormal value related to the degree of education, literacy (not education) group of 17 points or less, primary school (education duration of 6 years or less) group of 20 or less, secondary or above (education duration of > 6 years) group of 24 points or less, the following boundary value for cognitive function defect, above normal. | 20 minutes | 
| Hamilton Depression Rating Scale (HMAD) | Evaluating depression state:Normal score < 8 points, 8   20 points might be depression, 20   35 must have depression, > 35 severe depression. | 20 minutes | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Headache, Neuropsychological tests, Myofascial trigger points, electrophysiology