Relationship Between Muscle Strength and Quality of Life in ICU Survivors

Study Overview
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Brief Summary
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The aim is to study the impact of muscle strength measured in ICU and after ICU discharge on health-related quality of life measured after hospital discharge.

Official Title
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Relationship Between Grip and Quadriceps Strength on Quality of Life in ICU Survivors

Conditions
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Critical Illness, Muscle Strength, Quadriceps Strength, Grip Strength, Quality of Life

Intervention / Treatment
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* Diagnostic Test: handgrip strength
* Diagnostic Test: quadriceps strength


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: critically ill patients with an ICU stay of at least 7 days collaborative Exclusion Criteria: non collaborative, confusion, coma limb paresis or plegia patient refusal

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: handgrip strength|measure of handgrip strength using Jamar Dynamometer and a standardized protocol, strength expressed in kg|
|Diagnostic Test: quadriceps strength|maximal isometric quadriceps strength measured using a handheld dynamometer and a standardized protocol, strength expressed in Newton|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| health-related quality of life | assessed using the Sarcopenia Quality of Life (SARQOL) questionnaire short form: 8 questions with qualitative responses | 1 month after ICU discharge | 
| health-related quality of life | assessed using the Sarcopenia Quality of Life (SARQOL) questionnaire short form: 8 questions with qualitative responses | 3 months after ICU discharge | 
| health-related quality of life | assessed using the Sarcopenia Quality of Life (SARQOL) questionnaire short form: 8 questions with qualitative responses | 6 months after ICU discharge | 
| health-related quality of life | assessed using the EuroQOL 5 dimensions (EQ-5D) questionnaire: a first part assess the 5 dimensions of health state (each dimension is scored from 1 to 3, 3 indicating extreme problems). A second part is visual analog scale ranging from 0 (the worst health you can imagine) to 100 (the best health you can imagine) | 1 month after ICU discharge | 
| health-related quality of life | assessed using the EuroQOL 5 dimensions (EQ-5D) questionnaire: a first part assess the 5 dimensions of health state (each dimension is scored from 1 to 3, 3 indicating extreme problems). A second part is visual analog scale ranging from 0 (the worst health you can imagine) to 100 (the best health you can imagine) | 3 months after ICU discharge | 
| health-related quality of life | assessed using the EuroQOL 5 dimensions (EQ-5D) questionnaire: a first part assess the 5 dimensions of health state (each dimension is scored from 1 to 3, 3 indicating extreme problems). A second part is visual analog scale ranging from 0 (the worst health you can imagine) to 100 (the best health you can imagine) | 6 months after ICU discharge |