Whole Body Vibration in Chronic Obstructive Pulmonary Disease

Study Overview
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Brief Summary
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The investigators designed the current study with the main objective of determining whether Whole Body Vibration Training (WBVT) alone improves muscular force and/or modifies the functional capacity parameters in severe Chronic Obstructive Pulmonary Disease (COPD) patients referred to a rehabilitation programme.

Official Title
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Effects of Whole Body Vibration Training in Severe Chronic Obstructive Pulmonary Disease Patients

Conditions
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COPD

Intervention / Treatment
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* Device: A vertical vibration platform Fitybe


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: severe COPD defined as a post-bronchodilator forced expiratory volume at one second (FEV1)/ forced vital capacity (FVC) < 0.7 and FEV1 < 50% predicted, stable disease defined as no exacerbation, hospital admission or change in treatment in the previous 3 months. Exclusion Criteria: other significant respiratory disease (bronchiectasis, lung fibrosis, asthma, etc), active smoking, severe cardiovascular, neurological, and/or metabolic pathology that could interfere with the results, total hip, knee or ankle arthroplasty, previous vitreous haemorrhage, severe alcoholism (> 80 g/day) and severe malnutrition (BMI < 19 Kg/m2) to reduce the risk of falling and dropouts.

Ages Eligible for Study
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Minimum Age: 55 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: static work with a vertical vibration platform<br>The training was designed to perform static work of the lower limbs. Patients worked in a squatting position, with 30º of hip flexion and 55º of knee flexion, holding onto the bars of the WBV platform. | Device: A vertical vibration platform Fitybe<br>* They performed 6 series, and each series consisted of four 30-second repetitions with a frequency of 35 Hz and 2 millimeters of amplitude, with 60 seconds of rest between each series.<br>|
| No Intervention: Control group<br>general recommendations about physical activity and lifestyle | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| isokinetic knee flexor and extensor testing muscular force | the change between basal - and 3 months follow up. | basal, 3 months follow up | 
| distance performed in the six minutes walking test (6MWT) | the change between basal - and 3 months follow up. | Basal, 3 months follow up | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| respiratory muscular strength was assessed with maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP) | the change between basal - and 3 months follow up. | Basal, 3 month follow up |