Rotational Narrow Strip Versus Full Conjunctival Graft in Pterygium Excision

Study Overview
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Brief Summary
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To compare the efficacy of rotational narrow strip conjunctival graft to full conjunctival graft in primary pterygium excision. Risk analysis of factors that may affects the recurrence rate.

Detailed Description
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Pterygium is a raised, wing-shaped growth of fibrovascular tissue that extends horizontally from the bulbar conjunctiva, crossing the limbus, and onto the cornea. It is a common ocular surface disease in Malaysia. Pterygium can cause chronic ocular irritation, redness, tearing, visual impairment and poor cosmesis. Treatment of symptomatic pterygium remains surgical. Surgery should achieve low recurrence rate and acceptable cosmesis. Various surgical techniques had been described with variable success. In this study, we compared the efficacy of Rotational Narrow Strip Conjunctival Graft with the conventional full conjunctival graft in pterygium excision. Patient will be follow up for a year after pterygium surgery. Outcome will be recurrence rate between the two groups at one year. Risk analysis of certain factors that affects the recurrence rate will be discussed.

Official Title
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Rotational Narrow Strip Versus Full Conjunctival Graft in Pterygium Excision

Conditions
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Pterygium

Intervention / Treatment
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* Procedure: Rotational Narrow Strip Conjunctival Graft
* Procedure: Full Conjunctival Graft


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Significant and symptomatic primary pterygium clinically requiring excision Willingness to participate in research project and to attend research time Exclusion Criteria: Age < 21 years Glaucoma in the study eye Other concurrent ocular surface pathology Infection of the ocular surface Poor general health

Ages Eligible for Study
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Minimum Age: 21 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Rotational Narrow Strip Graft<br>Technique of surgery | Procedure: Rotational Narrow Strip Conjunctival Graft<br>* Surgical technique<br>|
| Active Comparator: Full Graft<br>Surgical technique | Procedure: Full Conjunctival Graft<br>* Surgical technique<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Recurrence Rate of Pterygium operated with Rotational Narrow Strip Conjunctival Graft and Full Conjunctival Graft Excision |  | 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Analysis of risk factors associated with recurrence of pterygium |  | 1 year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Pterygium