Evaluation of Dental Maturation and Mandibular Bone Morphology in Childhood Rheumatic Diseases

Study Overview
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Brief Summary
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The aim of our study is to examine possible disease-related changes in dental age and mandibular bone morphology in childhood rheumatic diseases.

Detailed Description
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to reveal the changes that can occur in different childhood rheumatic diseases, the treatment process of the disease and the drugs used on the dental age and mandible

Official Title
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Evaluation of Dental Maturation and Mandibular Bone Morphology in Childhood Rheumatic Diseases

Conditions
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Childhood Rheumatic Diseases

Intervention / Treatment
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* Radiation: Panoramic rad.


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients aged 6 to 14 years with childhood rheumatism Patients without bilateral congenital germ deficiency in the lower teeth Patients with seven teeth (except no #8) on the left of the mandibula (No seven teeth on the left of the mandibula, there should be a symmetrical tooth on the right of the mandibula. Exclusion Criteria: Patients with bilateral congenital germ deficiency in lower teeth in intraoral and/or radiographic examinations Patients with asymmetry and magnification errors and where anatomical structures cannot be seen clearly in the panoramic x-ray Patients with a significant number of missing teeth due to trauma or disease, root canal treatment, and pathological tooth structure Patients with a history of other chronic diseases

Ages Eligible for Study
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Minimum Age: 6 Years
Maximum Age: 14 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Screening
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Children diagnosed with childhood rheumatic disease<br> | Radiation: Panoramic rad.<br>* In the study, digital panoramic x-rays of the patients will be evaluated and dental age estimation with Willems method and mandibular bone morphometric measurements will be made.<br>|
| Experimental: Healthy children<br> | Radiation: Panoramic rad.<br>* In the study, digital panoramic x-rays of the patients will be evaluated and dental age estimation with Willems method and mandibular bone morphometric measurements will be made.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Dental Age Estimation | The study group will be comprised of newly diagnosed pediatric patients who applied to Umraniye Training and Research Hospital Division of Pediatric Rheumatology and whose treatment is ongoing, and the control group will be composed of pediatric patients without systemic disease who applied to Marmara University Faculty of Dentistry Department of Pedodontics. In the study, digital panoramic x-rays of the patients will be evaluated and dental age estimation with Willems method will be made. | 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mandibular bone morphometric measurements | The study group will be comprised of newly diagnosed pediatric patients who applied to Umraniye Training and Research Hospital Division of Pediatric Rheumatology and whose treatment is ongoing, and the control group will be composed of pediatric patients without systemic disease who applied to Marmara University Faculty of Dentistry Department of Pedodontics.For mandibular bone morphometric measurements, fractal analysis, that is a mathematical method describing and analyzing complex shapes and structural patterns such as the bone tissue, will be used in order to assess the bone density, using Image J software. A region of interest will be selected from panoramic radiographs. Image processing will be applied to correct for lightning irregularity, and box-counting method will be used to calculate a fractal dimension. | 3 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Childhood rheumatic diseases