Effectiveness Trial of the French Blues Indicated Depression Prevention Program

Study Overview
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Brief Summary
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The purpose of this pilot study is to test the effectiveness of French adaptation of the Blues program, a school-based indicated depression prevention intervention. The program will be delivered by the endogenous psycho-social staff of 3 Montreal secondary schools to adolescents with sub-clinical depressive symptoms and compared to a no-intervention (Informational Brochure only) control condition, designed to represent the usual intervention in these schools.

Official Title
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Pilot Effectiveness Trial of the French Blues Indicated Depression Prevention Program

Conditions
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Depression

Intervention / Treatment
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* Behavioral: Blues program


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Elevated depressive symptoms (score of 20 or above on the Center for Epidemiological Studies - Depression screening questionnaire) Exclusion Criteria: Current major depression diagnosis Current active suicidal behaviors Being in a special school curriculum for academic or behavioral problems

Ages Eligible for Study
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Minimum Age: 14 Years
Maximum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Blues program<br>Participants will attend 6 weekly 1-hour sessions of group cognitive-behavioral therapy administered by school staff, and will do home practice between sessions and after the program individually using a web site (called the Blues App) | Behavioral: Blues program<br>* Participants will attend 6 weekly 1-hour sessions of group cognitive-behavioral therapy administered by school staff, and will do home practice between sessions and after the program individually using a web site (called the Blues App)<br>|
| No Intervention: Control<br>Participants will receive a brochure describing the nature, causes, and consequences of depression, as well as available prevention/treatment options | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of participants who develop a major depressive episode as measured using the SCID diagnostic interview (posttest, 6 month follow-up) |  | 6 months | 
| Change in depressive symptoms as measured using continuous SCID scores (baseline, posttest, 6-month follow-up) |  | 6 months | 
| Change in depressive symptoms as measured using the CES-D questionnaire (baseline, posttest, 6-month follow-up) |  | 6 months | 
| Change in depressive symptoms as measured using the PHQ-9 questionnaire (baseline, posttest, 6-month follow-up) |  | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in social adjustment as measured using Évaluation sociale de Soi chez les jeunes adultes questionnaire (Michaud et al., 2006) (baseline, posttest, 6-month follow-up) |  | 6 months | 
| Change in anxiety symptoms as measured using the SCAS questionnaire (baseline, posttest, 6-month follow-up) |  | 6 months | 
| Change in parent-child relationship as measured using a scale from the MASPAQ questionnaire (Leblanc, 1996) (baseline, posttest, 6-month follow-up) |  | 6 months | 
| Change in affective school engagement as measured using a subscale of the school engagement questionnaire (Archambault et al., 2009) (baseline, posttest, 6-month follow-up) |  | 6 months | 
| Change in substance use as measured using a scale from the MASPAQ questionnaire (Leblanc, 1996) (baseline, posttest, 6-month follow-up) |  | 6 months | 
| Change in delinquent behaviors as measured using a scale from the MASPAQ questionnaire (Leblanc, 1996) (baseline, posttest, 6-month follow-up) |  | 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Depression, Prevention, Adolescents, School, Effectiveness