Alleviating Effects Against High Intraocular Pressure by Oral Intake of Cordyceps Cicadae Mycelia

Study Overview
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Brief Summary
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This study will investigate the effects of lowering intraocular pressure by oral intake of Cordyceps cicadae mycelia, to provide evidence-based data for high intraocular pressure relief.

Detailed Description
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Study purpose This study investigated the effeicacy of oral Cordyceps cicadae mycelia for the relief of high intraocular pressure. Subjects The total recruitment of subjects is 60 people, aged between 20 to 75 years. Subjects with intraocular pressure more than or equal to 21 mmHg are included, irrespective of whether on us of Taflotan (saflutan). Methods 1. Informed consents will be obtained from subjects first. The subjects with pre-test intraocular pressure over or equal 21 mm Hg are advised to orally take two capsules containing a total of 500 mg of Cordyceps cicadae mycelia. After 90 minutes, the subjects are evaluated for intraocular pressure. The pre-test and and post-intake intraocualr pressure and blood pressure data will be compared by paired t test for significant differences if any.

Official Title
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Alleviating Effects Against High Intraocular Pressure by Oral Intake of Cordyceps Cicadae Mycelia

Conditions
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Supplement

Intervention / Treatment
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* Dietary Supplement: Cordyceps Cicadae Mycelia


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age between 20 and 75 years old, regardless of gender. Pre-test confirmation of high intraocular pressure. Subjects should understand the trial and agree to join the project. Exclusion Criteria: Age under 20 or over 75 years. Use intraocular pressure lowering drugs other than Taflotan (saflutan). Using beta-blockers or diuretics. Being pregnant. Disabled individuals with specific diseases or malfunction, for example tumours at terminal stage, blindness. Loss of self-consciousness and behavioral capacity. Patients with major diseases. Withdrawal criteria All subjects may withdraw at any time without any reason. The act of withdraw does not affect rights for them to seek medical advice or treatments.

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Two groups of subjects are subject to pre-test and post-test intraocular pressure measurements.
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Cordyceps Cicadae Mycelia only<br>Only Cordyceps Cicadae Mycelia will be given. | Dietary Supplement: Cordyceps Cicadae Mycelia<br>* Cordyceps Cicadae Mycelia will be given to test its potential for alleviation of high intraocular pressure.<br>|
| Experimental: Cordyceps Cicadae Mycelia with Taflotan (saflutan)<br>Cordyceps Cicadae Mycelia with Taflotan (saflutan) will be given. | Dietary Supplement: Cordyceps Cicadae Mycelia<br>* Cordyceps Cicadae Mycelia will be given to test its potential for alleviation of high intraocular pressure.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Intraocular pressure | Intraocular pressure of both eyes will be assessed | 0 minutes (before given Cordyceps Cicadae Mycelia) | 
| Intraocular pressure | Intraocular pressure of both eyes will be assessed | 90 minutes after given Cordyceps Cicadae Mycelia | 
| Blood pressure | Both systolic and diastolic blood pressures will be assessed | 0 minutes (before given Cordyceps Cicadae Mycelia) | 
| Blood pressure | Both systolic and diastolic blood pressures will be assessed | 90 minutes after given Cordyceps Cicadae Mycelia |