linjc16/ctgov huggingface dataset:
Evaluation of Analgesia by PENG Block Versus Intra-Articular Infiltration in Prosthetic Hip Surgery (API)

Study Overview
=================
Brief Summary
-----------------
The main objective of this study is to compare the effectiveness of the ultrasound-guided PENG block technique compared to intra-articular infiltration on morphine consumption during hip prosthetic surgery via the anterior minimally invasive approach under general anesthesia.

Official Title
-----------------
Evaluation of Analgesia by PENG Block Versus Intra-Articular Infiltration in Prosthetic Hip Surgery

Conditions
-----------------
Hip Prosthesis, Analgesia, PENG Block

Intervention / Treatment
-----------------
* Procedure: Prosthetic hip surgery


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patient, male or female, over 18 years old. Patient scheduled for anterior hip prosthesis. Affiliated patient or beneficiary of a social security scheme. Patient having been informed and having signed a free and informed consent. Exclusion Criteria: Patient with a contraindication to local anesthesia. Patient with a high level of dependence, defined by level 1 or 2 of the Iso-Ressources Group (GIR). Patient participating in another clinical study. Protected patient: adult under guardianship, curatorship or other legal protection, deprived of freedom by judicial or administrative decision. Pregnant, breastfeeding or parturient woman. Patient hospitalized without consent.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Patients with PENG block<br> | Procedure: Prosthetic hip surgery<br>* Total hip prosthesis performed by an anterior approach with intra-articular infiltration of an anesthetic product intraoperatively. OR - Total hip prosthesis performed by an anterior approach with infiltration of the same anesthetic product by ultrasound-guided PENG block intraoperatively.<br>|
| Active Comparator: Patients with intra-articular infiltration<br> | Procedure: Prosthetic hip surgery<br>* Total hip prosthesis performed by an anterior approach with intra-articular infiltration of an anesthetic product intraoperatively. OR - Total hip prosthesis performed by an anterior approach with infiltration of the same anesthetic product by ultrasound-guided PENG block intraoperatively.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Total amount of morphine (mg) | total amount of morphine administered intraoperatively, in milligrams. | 45 days |
Hepatitis C: Grading and Staging by MR

Study Overview
=================
Brief Summary
-----------------
To compare MR imaging findings with biopsy for grading and staging early hepatitis C.

Official Title
-----------------
Hepatitis C: Grading and Staging by MR

Conditions
-----------------
Hepatitis

Participation Criteria
=================
Eligibility Criteria
-----------------
Referral only

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Hepatitis C
Predictive Value of the DD4 Questionnaire on Depressive Relapse After Hospitalization.

Study Overview
=================
Brief Summary
-----------------
This is a prospective, longitudinal, single-center observational study of data from the medical records of patients hospitalized after a characterized depressive episode and reviewed three months after hospital discharge, as part of a normally scheduled evaluation.

Detailed Description
-----------------
Patients in the study were hospitalized following a characterized depressive episode. The study is based on a review of these patients' medical records and data from the three-month assessment. No additional assessments are planned.

Official Title
-----------------
Predictive Value of the DD4 Questionnaire on Depressive Relapse After Hospitalization.

Conditions
-----------------
Depressive Episode

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patient 18 years of age or older, having been informed of the research Patient hospitalized at the Auzon Clinic for a characterized depressive episodé (isolated episode or recurrent depressive disorder) Discharged from hospitalization Considered in remission (total or partial) and with a MADRS score < 20 Exclusion Criteria: Patient hospitalized for < 15 days Patient with bipolar depression Patient with a psychotic disorder Patient using narcotics with a moderate to severe severity Patient previously included in this study Patient under court protection, guardianship or curatorship Patient unablé to respond correctly to a depression self-assessment questionnaire

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Depressive episode relapse | Relapse within three months of hospitalization | Month 3 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Psychic symptoms of depression | The Ducher DD4 scale is presented in the form of four modules that assess the same questionnaire in different ways. The questionnaire consists of 15 items evaluating the psychic symptoms of depression (somatic criteria were not retained in order to allow the use of this instrument in patients with an associated physical pathology. | Month 3 | 
| Evaluation of depressive symptomology | Measured with the Montgomery and Asberg (MADRS) scale | Month 3 |
Open-label Study to Investigate Systemic Exposure in Adult and Pediatric Atopic Dermatitis Patients Treated 8.5 Days With Pimecrolimus Cream 1% Under Occlusion

Study Overview
=================
Brief Summary
-----------------
This study will access the degree to which pimecrolimus is absorbed from pimecrolimus cream 1% into the blood when applied repeatedly under occlusion (i.e. areas treated wrapped in a plastic film) over 8 days in patients with moderate to severe atopic eczema.

Official Title
-----------------
Non-comparative Open-label Study to Investigate the Efficacy, Safety and Systemic Exposure of Pimecrolimus in Adult and Pediatric Patients With Moderate to Severe Atopic Dermatitis Treated Topically for 8.5 Days With Pimecrolimus Cream 1% Under Occlusion

Conditions
-----------------
Atopic Dermatitis

Intervention / Treatment
-----------------
* Drug: Pimecrolimus


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients 2 - 18 years of age Patients with a diagnosis of moderate to severe atopic dermatitis, assessed by a score ≥ 3 at the Investigator's Global Assessment. AD to involve at least 30% of their body surface area as determined by the rule of nine or the Lund and Browder chart. Exclusion Criteria: Erythrodermic patients with Netherton's syndrome Patients with known serious adverse reactions or hypersensitivity to any of the excipients of the study medication Patients with a history of cancer, skin malignancy or lymphoproliferative disorders or of immunocompromise, including a positive HIV (ELISA and Western blot), Hepatitis B surface antigen (HBsAg) or Hepatitis C test result Other protocol-defined inclusion/exclusion criteria may apply

Ages Eligible for Study
-----------------
Minimum Age: 2 Years
Maximum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Pimecrolimus cream 1%<br>Pimecrolimus | Drug: Pimecrolimus<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pimecrolimus blood concentration |  | Days 1, 9, 16 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Efficacy as assessed by the Eczema Area and Severity Index and the Investigators Global Assessment of disease severity. Efficacy outcomes were of an exploratory nature in this study. |  | Days 1, 9, 16 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Atopic dermatitis, AD, pimecrolimus, blood, absorption, systemic
Chairside Time and Bond Failure of Non Custom Versus Custom Base Orthodontic Attachments During Indirect Bonding

Study Overview
=================
Brief Summary
-----------------
compare the chair side time, clinical orthodontic attachment bond failure and accuracy of transfer between non custom attachment base and custom attachment base indirect techniques.

Official Title
-----------------
Chairside Time and Bond Failure of Non Custom Versus Custom Base Orthodontic Attachments During Indirect Bonding: A Randomized Clinical Trial

Conditions
-----------------
Orthodontic Appliance Complication

Intervention / Treatment
-----------------
* Device: non custom base attachment
* Device: custom base attachment


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: - Patients should have Maxillary sound teeth and undergoing fixed orthodontic treatment. Space problems ranging from spacing to mild crowding. Good oral hygiene. Exclusion Criteria: Patients with partially erupted teeth in the maxillary arch . Signs of caries, large restorations fluorosis, hypoplasia or abnormalities of crown morphology. The need of banding. Bad oral hygiene measures.
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: non custom base attachment<br> | Device: non custom base attachment<br>* non custom base attachment<br>|
| Active Comparator: custom base attachment<br> | Device: custom base attachment<br>* custom base attachment<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| chair side time | using stopwatch | an average of 30 minutes | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| immediate bond failure | number of debonded attachments using hand instrument pressure | immediately after bonding |
The Effect of Radiofrequency-treatment on Patients With Facet-joint Pain in Cervical- and Lumbar-columna

Study Overview
=================
Brief Summary
-----------------
There is conflicting evidence on whether radio-frequency neurotomy of the medial branch has a significant effect on pain in patients with chronic unilateral facet joint neck and back pain. We will evaluate radiofrequency treatment on medial-branch of the ramus dorsalis as an effective pain treatment for patients with chronic pain originated from facet-joints in cervical and lumbar columna.

Official Title
-----------------
The Effect of Radiofrequency-treatment on Patients With Facet-joint Pain in Cervical- and Lumbar-columna

Conditions
-----------------
Neck Pain, Low Back Pain

Intervention / Treatment
-----------------
* Procedure: radiofrequency treatment
* Procedure: sham neurotomy


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: one-sided neck and low back chronic pain pain durability of at least 1 year Exclusion Criteria: other somatic or psychiatric disorders pregnancy stated co-morbidity anaesthetics intolerance no effect of diagnostic blockades (one or two)

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: radiofrequency neurotomy<br>Radiofrequency-neurotomy of the medial branch at 80 degr. C for 70 seconds, after diagnostic blocks | Procedure: radiofrequency treatment<br>* Radiofrequency-neurotomy of the medial branch at 80 degr. C needle temperature for 70 seconds, after diagnostic blocks<br>|
| Sham Comparator: sham controls<br>Radiofrequency-neurotomy of the medial branch at 37 degr. C needle temperature for 70 seconds, after diagnostic blocks | Procedure: sham neurotomy<br>* Radiofrequency-neurotomy of the medial branch at 37 degr. C needle temperature for 70 seconds, after diagnostic blocks<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| reduction in self-reported pain intensity | Numerig rating scale 1 to 10 | up to 1 year | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
radiofrequency
Last 3 Months of Life in Home Ventilated Patients

Study Overview
=================
Brief Summary
-----------------
To verify with a specific questionnaire, the families' perceived quality of end-of-life care and of dying in the last 3 months of life of 168 patients (Chronic Obstructive Pulmonary Disease-Amyotrophic Lateral Sclerosis (ALS)-Restrictive disorders-Neuromuscular disease- others) with chronic respiratory failure needing domiciliary mechanical ventilation (MV).

Detailed Description
-----------------
Participants: 168 patients' relatives presenting five categories of diseases (Chronic Obstructive Pulmonary Disease-Amyothrophic Lateral Sclerosis (ALS)-Restrictive disorders-Neuromuscular disease- others) answered to questionnaire. Interventions: none Measurements and Main Results: 35 questions grouped in 6 specific domains (Control of pain and symptoms (domain 1-D1), awareness of disease (D2), family burden (D3), the process of dying (D4), medical troubles including hospitalizations (D5) and technical problems linked to MV(D6) were asked after the patient's death to a family member by means of a face to face interview. Answers to the binary 35-item questionnaire were distributed into just two clusters per each domain.

Official Title
-----------------
Italian Multicenter Survey on the Last 3 Months of Life in Patients Ventilated at Home

Conditions
-----------------
Respiratory Failure

Intervention / Treatment
-----------------
* Other: survey administration


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion criteria: All patients mechanically ventilated at home who died Exclusion criteria: patients with cancer

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| family burden<br>chronich respiratory failure home ventilated patients | Other: survey administration<br>* application of a family survey on last 3 months of life for their relatives under HMV<br>* Other names: caregiver burden;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| level of family burden |  | 3 months after patient's death | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| influence of diagnosis and modality of ventilation |  | 3 months after patient's death | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
ethics, COPD, end of life, mechanical ventilation, CRF home ventilated patients
The Prediction of Preeclampsia/Toxemia in Twin Pregnancy

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to finout whetere uterinae artery flow , PP13 and endogolin levels in the serum and kongo red in the urine can predict preeclamsia toxemia in twin pregnancies.

Official Title
-----------------
Prospective Longitudenal Study in the Prediction of Preeclampsia/Toxemia in Twin Pregnancy

Conditions
-----------------
Preeclampsia/Toxemia

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: a women with a vaiable twin pregnany Exclusion Criteria: women with thrombophilya women terated with anticoagolant women with vascular disease

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 60 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| twin preganacies<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
preeclampsia, toxemia, twin, pregnancy, pp13, prediction, kongo red
The Acceptability of a Real-time Localization for Patients and Caregivers

Study Overview
=================
Brief Summary
-----------------
Technological innovations are taking over our daily lives, particularly in the health sector. Real-time location systems for healthcare professionals and patients are developing in hospitals. Today few studies have focused on the acceptability of this new technology. The present research, which aims to study the acceptability of a real-time localization systems, reveals a definite utility and acceptability from the patient's point of view, subject to conditions. Indeed, the guarantee of data security and the concrete interest for the patient must be explained. For healthcare professionals working in emergency departments, the usefulness of new technologies in their work is now well established. Nevertheless, the acceptability of a real-time location systems received lukewarm reviews. It depends mainly on reticence linked to the fear of a possible deviation in the use of the data collected.

Detailed Description
-----------------
study the acceptability of a real-time localization of patients and caregivers

Official Title
-----------------
The Acceptability of a Real-time Localization of Patients and Caregivers

Conditions
-----------------
Disease

Intervention / Treatment
-----------------
* Other: Individual interviews


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: For general population : people have been hospitalized at least once For caregivers : works in emergency service Exclusion Criteria: Person with a neurological disease Person under guardianship or curatorship

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| General population<br>general population | Other: Individual interviews<br>* Discussion between the searcher and the participant about representations and acceptability about a potential real time localization system<br>|
| emergency caregivers<br>emergency caregivers | Other: Individual interviews<br>* Discussion between the searcher and the participant about representations and acceptability about a potential real time localization system<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| opinion and representations about a real time localization system | Measure by individual interviews | Days:30 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Acceptability study, new technologies, health sector, real time location system
Child With Anomalous Drainage of IVC to Left Atrium

Study Overview
=================
Brief Summary
-----------------
The purpose is to see if any conclusions can be drawn about the uncommon heart defect: anomalous drainage of the inferior vena cava to the left atrium.

Detailed Description
-----------------
Dr. Kogon would like to do a case-report and review of the literature regarding children with the diagnosis of anomalous drainage of the inferior vena cava to the left atrium. At Children's Healthcare of Atlanta, we have seen a single patient with this diagnosis in 2004 and Dr. Kogon would like to discuss this patient in combination with the others already in the literature to see if any conclusions can be drawn about this uncommon heart defect. Currently there are about 20 cases reported in the literature and Dr. Kogon will be reporting on this one case seen in 2004. The case report of our patient will utilize his medical chart. We hope to provide a brief summary of his clinical presentation, his radiographic evaluation, his operative findings, and his outcome. The only PHI that will be collected will be dates (i.e. date of birth, dates of procedures).

Official Title
-----------------
A Case Report of a Child With Anomalous Drainage of the Inferior Vena Cava to the Left Atrium

Conditions
-----------------
Congenital Disorders

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: single case child with anomalous drainage of the inferior vena cava to the left atrium at Children's Healthcare of Atlanta Exclusion Criteria: -
Sexes Eligible for Study
-----------------
Male

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
pediatric health, children, single case study