The Effect of Virtual Reality Exercises on Patients With Post-SARS-CoV-2 Syndrome

Study Overview
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Brief Summary
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The aim of this study is to investigate the effectiveness of virtual reality exercises on pain, cardiopulmonary capacity, mood and quality of life in patients with post-COVID syndrome.

Detailed Description
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This study, which will be conducted in Sivas Cumhuriyet University, Physical Medicine and Rehabilitation Clinic, was diagnosed with COVID-19 from an oropharyngeal or nasopharyngeal swab sample more than 90 days ago with polymerase chain reaction, whose symptoms have continued since the diagnosis of COVID-19, and inpatient treatment. 63 adult female and male post-COVID syndrome patients who did not develop pneumonia or organ failure findings will be included. Those who have had acute myocardial infarction in the last 6 months, have cardiovascular system disease such as uncontrolled hypertension, arrhythmia, aneurysm, cardiac failure, have undergone fracture or orthopedic surgery in the last 3 months, have a known chronic respiratory system disease, cause widespread pain such as fibromyalgia syndrome Those who have a disease or cannot be mobilized independently will not be included in the study. The sample size was determined as d=0.80 α=0.05 p=0.80410 n=54 using the G*Power 3.1.9.4 program. Considering the 15% drop-out risk, 63 patients were planned to be included. Demographic data of all participants, including age, gender, height, weight and body mass index, and the time elapsed since the diagnosis of COVID-19 will be recorded. In addition, participants' pain intensity, functional capacity, general health status, mood, and fatigue levels will be evaluated.

Official Title
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The Effect of Virtual Reality Exercises on Pain, Cardiopulmonary Functional Capacity and Quality of Life in Patients With Post-COVID Syndrome

Conditions
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Covid19

Intervention / Treatment
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* Other: Virtual Realty Exercises
* Other: Aerobic exercises
* Other: conventional exercises


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: diagnosed with COVID-19 by polymerase chain reaction from an oropharyngeal or nasopharyngeal swab sample more than 90 days ago, whose symptoms have continued since the diagnosis of COVID-19 Exclusion Criteria: have been hospitalized due to COVID-19, have developed pneumonia or organ failure findings. have had an acute myocardial infarction in the last 6 months, have cardiovascular system disease such as uncontrolled hypertension, arrhythmia, aneurysm, cardiac failure, have undergone fracture or orthopedic surgery in the last 3 months, have a known chronic respiratory system disease, have widespread pain such as fibromyalgia syndrome

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Virtual Realty<br>Participants will play a motion-controlled video game with Microsoft XBox One Kinect for 30 minutes, three days a week, for 8 weeks and lower and upper extremity stretching, strengthening and endurance exercises | Other: Virtual Realty Exercises<br>* motion-controlled video game<br>Other: conventional exercises<br>* stretching, strengthening and endurance exercises<br>|
| Active Comparator: Conventional<br>Participants will do aerobic exercises for 30 minutes, three days a week, for 8 weeks and lower and upper extremity stretching, strengthening and endurance | Other: Aerobic exercises<br>* cycling activity<br>Other: conventional exercises<br>* stretching, strengthening and endurance exercises<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| visual Analogue Scale |  | 8th week | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| hospital anxiety and depression scale-Depression |  | 0th and 8th week | 
| hospital anxiety and depression scale-Anxiety |  | 0th and 8th week | 
| Fatigue severity scale |  | 0th and 8th week | 
| Short Form-12 |  | 0th and 8th week | 
| 6 minutes walking test |  | 0th and 8th week |