Bowel Preparation for Repeat Colonoscopy After Preparation Failure (RepeatPrep Study)

Study Overview
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Brief Summary
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This trial will evaluate the efficacy in colon cleansing of a nurse-led educational telephone intervention 24-48 hours before a colonoscopy, in selected participants with a previous inadequate bowel preparation.

Official Title
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Nurse-led Educational Telephone Intervention for Bowel Preparation for Repeat Colonoscopy After Preparation Failure (RepeatPrep Study)

Conditions
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Bowel Preparation for Colonoscopy

Intervention / Treatment
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* Behavioral: Educational telephone intervention
* Behavioral: Standard education for colonoscopy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Consecutive patients with a colonoscopy with inadequate bowel preparation, for any indication and where the endoscopist considers that the colonoscopy should be repeated to optimize the visualization with a better bowel preparation. Participants must have been properly informed and they have to sign the inform consent. Exclusion Criteria: Hospitalized patients Unwillingness to participate in the study Inability to follow instructions: cognitive impairment or language barrier Inability to use a telephone or not owning a telephone Active inflammatory bowel disease Severe renal impairment Pregnancy of breast feeding

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Educational telephone intervention<br>This group will receive a nurse-led educational telephone intervention for bowel preparation 24-48 before the colonoscopy | Behavioral: Educational telephone intervention<br>* Subjects will receive a nurse-led educational telephone intervention for bowel preparation 24-48 hours before the colonoscopy<br>|
| Active Comparator: Standard education for colonoscopy<br>The control group will receive standard education for bowel preparation at the time of colonoscopy scheduling | Behavioral: Standard education for colonoscopy<br>* Standard education for bowel preparation at the time of colonoscopy scheduling<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Adequate bowel cleansing for colonoscopy | The efficacy of bowel preparation will be rated by blinded endoscopists using the Boston Bowel Preparation Scale (BBPS). Adequate bowel cleansing will be defined as a BBPS of 2 or more points in every segment of the colon and inadequate bowel cleansing will be defined by at least one of the colon segments with less than 2 points. | At the moment of colonoscopy | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Overall adenoma detection rate, as defined by the ratio of patients with at least one adenoma in the overall colon | The ratio of patients with at least one adenoma in the overall colon | At the moment of colonoscopy | 
| Adenoma detection rate in the right colon | Ratio of patients with at least one adenoma in the right colon (proximal to the splenic flexure) | At the moment of colonoscopy | 
| Overall serrated lesion detection rate | Ratio of patients with at least one serrated lesion in the overall colon | At the moment of colonoscopy | 
| Serrated lesion detection rate in the right colon | Ratio of patients with at least one serrated lesion in the right colon (proximal to the splenic flexure) | At the moment of colonoscopy | 
| Complete colonoscopy rate | Ratio of successful complete colonoscopies (cecal intubation or in case of previous surgery, ileocolic anastomosis) | At the moment of colonoscopy | 
| Boston Bowel Preparation Scale | Application of the Boston Bowel Preparation Scale to evaluate colonoscopy bowel cleansing | At the moment of colonoscopy | 
| Barcelona Bowel Preparation Scale | Application of the Barcelona Bowel Preparation Scale to evaluate colonoscopy bowel cleansing | At the momento of colonoscopy | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Colonoscopy, Educational intervention