Epidemiological Study of the Covid-19 Presto Test - The COVIDOR Study

Study Overview
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Brief Summary
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The COVIDOR epidemiological study. Our study would be the first at the community level in Orleans Métropole, aiming to determine the link between a positive IgM level on the serological test and a healthy carrier of covid-19 in agents in contact with the public. It would provide epidemiological surveillance of anti-covid-19 immunity in the community

Detailed Description
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The metropolitan area of Orléans Métropole has 6,700 agents divided into 250 different trades and consequently multiple exposures and risks. The global covid-19 pandemic has affected France and the Loiret, the sarscov-2 coronavirus, has infected several thousand people. On May 7, 2020, there were 75 deaths at the CHRO hospital in Orleans, excluding EHPAD. The contamination rate of the population of the Loiret department has been estimated at 5.6% of the population by Public Health France. This rate is very low and does not allow the use of serological screening tests because of too many false positives or false negatives, there should be a prevalence of the disease greater than 60%. The French health authorities do not recommend the use of a screening test at the present time in view of the uncertainties of the results of this test. The Loiret Management Center, the Department and Orléans Métropole have decided to offer a covid-19 serological screening test, the covid-19 presto test, to voluntary territorial agents regardless of their return to work following the national deconfinement on May 11, 2020 This can only be done through an epidemiological surveillance study validated as part of a research protocol.

Official Title
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Epidemiological Study of the Covid-19 Presto Test Among Agents of the Local Authorities of CCTVL, Region Centre Val de Loire and Orleans Métropole. Correlation of IgM Level According to Contact With the Public

Conditions
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Coronavirus Infection

Intervention / Treatment
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* Diagnostic Test: Covid-19 presto test


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All the agents of the 3 local authorities (Loire Valley Region, CCTVL and Orléans Métropole) being voluntary to be tested for the COVID-PRESTO® test COVID-19 IgG / IgM rapid test (whole blood / serum / plasma) - Cassette Volunteer to get tested Exclusion Criteria: Opposition to the participation of the study Covid-19 disease

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| agents in contact with the public<br>patients working with children, policemen, desk office | Diagnostic Test: Covid-19 presto test<br>* Use an auto-test in 15 minutes get the results about covid-19 anticorps<br>* Other names: Covid-19 viro;|
| agents with no contact with the public<br>administrative workers | Diagnostic Test: Covid-19 presto test<br>* Use an auto-test in 15 minutes get the results about covid-19 anticorps<br>* Other names: Covid-19 viro;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Study the prevalence of Covid-19 infection, coronavirus (SARS coronavirus-2) in territorial agents in the 3 structures : CCTVL, Loire Valley Region Centre, Orleans Metropolitan city | Covid-19 attack rate by measuring the frequency of anti-covid-19 IgM in each of the territorial structures | 15 minutes | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Determine if there is a relationship between the profession carried out by the agents of the territorial community of Orleans metropolitan city, the Loire Valley Region, the CCTVL and contamination by covid-19 | Search for a correlation of covid-19 immunity based on the officer's position, if he is in contact with the public. | 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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covid-19, serology, depistage, public health, voluntary agents