Healthy Adult Male Facial Skin Surface Lipid Pheromone p.o. to Treat Opioid Addiction

Study Overview
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Brief Summary
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Healthy adult human male facial skin surface lipid liquid pheromone given by mouth to opioid addicts cures them without any withdrawal symptoms whatsoever 250mg on chewing gum vehicle by mouth. Elevated mood eventually becomes accommodated after a few weeks. The pheromone contains volatile airborne sub-pheromones which cause aversive behavior (distrust, superstition, suspicion, arrogance, astonishment/stupidity, jealousy). Artificial jealousy can be avoided by patient isolation for 40 days until the pheromone taste wears off the saliva. The pheromone provided is odorless, colorless, and tasteless to the conscious brain.

Detailed Description
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Healthy adult human male facial skin surface lipid liquid pheromone given by mouth to opioid addicts cures them without any withdrawal symptoms whatsoever 250mg on chewing gum vehicle by mouth. Elevated mood eventually becomes accommodated after a few weeks. The pheromone contains volatile aversive sub-pheromones which cause aversive behavior (distrust, superstition, suspicion, arrogance, astonishment/stupidity, jealousy). Artificial jealousy can be avoided by patient isolation for 40 days until the pheromone taste wears off the saliva. The pheromone provided is odorless, colorless, and tasteless to the conscious brain. Pheromone action is insidious. The lifting of the appetite for addictive drugs monkey on the back feeling is gratifying. Ambition returns and ambitions are realized. To mitigate aversive airborne sub-pheromone methyl esters (almost certainly the cause of artificial aversive emotions), we will be trying several attenuation strategies. Staff collecting, storing, and dispensing pheromone (and placebo) will utilize the provided 3M Versaflo supplied air carbon filtered respirator for pharmaceutical applications. Collection from volunteer pheromone donors and administration to tox screened opioid addicts will be in areas ventilated by Dyson carbon-filtered oscillating fans placed to break up plumes of airborne sub-pheromone sufficiently to attenuate aversive emotion. Other lab techniques will also be tried as artificially stimulated emotional and heartfelt complaints are expected, from everybody. Unfortunately, the rapid process of healing opioid addiction will involve the unavoidable creation of potentially problematic emotions. We will try smaller daily doses, reverse Fisher esterification with apple cider vinegar, more vigorous air disturbances, negative air pressure, fume hoods, isolation, etc.

Official Title
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The Nicholson Science Pheromone Trial

Conditions
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Opioid Use, Opioid Intoxication, Opioid Abuse, Episodic, Opioid Addiction, Opioid Abuse, Continuous Use, Opioid-Related Disorders, Paternal Pheromone Deficiency, Opioid Dependence, Opioid Abuse, Opioid-use Disorder

Intervention / Treatment
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* Biological: 250mg healthy adult male facial skin surface lipid liquid pheromone


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Dirty Tox Screen showing recent and continuing opioid drug dependence - Exclusion Criteria: Pregnant people, people who desire to retain their paraphilia -

Ages Eligible for Study
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Minimum Age: 12 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Crossover Assignment
Interventional Model Description: Double-blind, cross-over, placebo-controlled clinical trial in hospital setting overseen by attending physician, χ2 test for categorized data
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Experimental Group<br>250mg p.o. of healthy adult male facial skin surface lipid liquid pheromone on fresh, new, just-purchased, un-chewed Wrigley's Rain #5 sugarless chewing gum vehicle. 15 pieces or divided as tolerated. | Biological: 250mg healthy adult male facial skin surface lipid liquid pheromone<br>* Human Pheromone provided p.o. to tox-screen verified opioid drug addict<br>* Other names: Paternal Facial Pheromone;|
| Placebo Comparator: Placebo Group<br>Placebo identical to Experimental dose with randomly assigned identification numbers on unopened, unsealed key. Placebo and Experimental doses kept together and undifferentiable without the key being opened. Key available for opening 24/7 w/pharmaceuticals tech onsite. Keep pheromone/placebo doses under a fume hood. Wear 3M Versaflo activated charcoal filter supplied air respirator or equivalent to access. | Biological: 250mg healthy adult male facial skin surface lipid liquid pheromone<br>* Human Pheromone provided p.o. to tox-screen verified opioid drug addict<br>* Other names: Paternal Facial Pheromone;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Clean Tox Screen, UDS, urinary drug screen | no drug use since pheromone provided. Urinary Drug Screens are among the most common medical tests in hospitals. Positive or Dirty urinary drug screens are routinely followed up with gas chromatography--mass spectrometry to assure test results. | six weeks, all common opioids clear in six weeks time. Cannabis may take a little longer than six weeks to clear, but we are not really interested in that, are we? | 
| Dirty Tox Screen | Continued heavy drug use comparable to initial Tox Screen testing. Urinary Drug Screens are among the most common medical tests in hospitals. Positive or Dirty urinary drug screens are routinely followed up with gas chromatography--mass spectrometry to assure test results. | six weeks, all common opioids clear in six weeks time. Cannabis may take a little longer than six weeks to clear, but we are not really interested in that, are we? |