Surgical Management of Pseudophakic and Aphakic Retinal Detachment; a Randomized Clinical Trial

Study Overview
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Brief Summary
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To compare the visual and anatomical outcomes and complications of four surgical techniques (1- scleral buckling, 2- primary vitrectomy without encircling band, 3- primary vitrectomy with encircling band, 4- triamcinolone assisted vitrectomy) for management of pseudophakic and aphakic retinal detachment

Conditions
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Pseudophakic Retinal Detachment, Aphakic Retinal Detachment

Intervention / Treatment
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* Procedure: scleral buckling, primary vitrectomy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Cases of pseudophakic and aphakic retinal detachment with PVR grade A or B Exclusion Criteria: PVR grade C History of surgery for RD Signs of diabetic retinopathy, AMD, glaucoma and macular hole History of ocular trauma Giant retinal tear

Ages Eligible for Study
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Minimum Age: 40 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: 1<br>scleral buckling | Procedure: scleral buckling, primary vitrectomy<br>* Four different surgical techniques were performed(one in each arm); 1- scleral buckling, 2- primary vitrectomy without encircling band, 3- primary vitrectomy with encircling band, 4- triamcinolone assisted vitrectomy<br>|
| Active Comparator: 2<br>Primary vitrectomy without encircling band | Procedure: scleral buckling, primary vitrectomy<br>* Four different surgical techniques were performed(one in each arm); 1- scleral buckling, 2- primary vitrectomy without encircling band, 3- primary vitrectomy with encircling band, 4- triamcinolone assisted vitrectomy<br>|
| Active Comparator: 3<br>Primary vitrectomy with encircling band | Procedure: scleral buckling, primary vitrectomy<br>* Four different surgical techniques were performed(one in each arm); 1- scleral buckling, 2- primary vitrectomy without encircling band, 3- primary vitrectomy with encircling band, 4- triamcinolone assisted vitrectomy<br>|
| Active Comparator: 4<br>Triamcinolone assisted vitrectomy | Procedure: scleral buckling, primary vitrectomy<br>* Four different surgical techniques were performed(one in each arm); 1- scleral buckling, 2- primary vitrectomy without encircling band, 3- primary vitrectomy with encircling band, 4- triamcinolone assisted vitrectomy<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Retinal reattachment rate |  |  | 
| Visual acuity |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Proliferative vitreoretinopathy |  |  | 
| Macular Pucker |  |  | 
| Anisometropia |  |  | 
| Choroidal detachment |  |  | 
| Reoperation |  |  | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Pseudophakic retinal detachment,, Aphakic retinal detachment,, Scleral buckling,, Primary vitrectomy,, Proliferative vitreoretinopathy