Effects of the Physical Fitness on Serum Klotho Levels in Healthy Population

Study Overview
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Brief Summary
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Exercise program in serum Klotho levels

Detailed Description
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This study aims to analiyze the effects of acute exercise in serum Klotho levels attending physical fitness in healthy population

Official Title
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Effects of the Physical Fitness on Serum Klotho Levels in Healthy Population: Response and Adaptation

Conditions
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Healthy Population

Intervention / Treatment
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* Other: plyometric exercise
* Other: Aerobic exercise


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: healthy people between 20 and 45 years old Exclusion Criteria: acute and chronic disease, people who take medication and supplements, smoker.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Single Group Assignment
Interventional Model Description: Description of the sample
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Plyometric<br>Effects of plyometric acute exercise | Other: plyometric exercise<br>* acute plyometric exercise<br>|
| Experimental: Aerobic<br>Effects of aerobic acute exercise | Other: Aerobic exercise<br>* acute aerobic exercise<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in serum Klotho levels | Change from baseline to acute exercise session | Baseline and one hour | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Cardiorespiratory Fitness VO2max | For this Variable All people Will perform a exercise test on treadmill (Tecnhogym run race 1400HC; Gambettola, Italy), in this way we determinate the VO2max. Through the modifies Balke protocol. The gas Exchange data Will measured breath by breath using open circuit spirometry and specific face mask for Fitmate, Cosmed; Vmax 29C, Sensormedics machine. | Baseline | 
| Change in Body Composition | The age in years; height in centimeters (tallimeter Ano Sayol SL, Barcelona, Spain); weight in kilograms (Inbody 720, Microcaya) and we can derive from this data the variable of Body Mass Index (BMI) calculated as weight (kg)/height (m2). | Baseline | 
| Change in Body Composition, Body muscle mass Index | For determinate this variable of the body composition will be use a Dual Densitometry X-Ray (DXA) (Hologic QDR Discovery, Bedford, MA, USA) | Baseline | 
| Change in Body Composition, % of Fat Mass | For determinate this variable of the body composition will be use a Dual Densitometry X-Ray (DXA) (Hologic QDR Discovery, Bedford, MA, USA) | Baseline | 
| Change in Body Composition, Total Muscle Mass | For determinate this variable of the body composition will be use a Dual Densitometry X-Ray (DXA) (Hologic QDR Discovery, Bedford, MA, USA) | Baseline | 
| Change in Body Composition, Visceral Fat Index. | For determinate this variable of the body composition will be use a Dual Densitometry X-Ray (DXA) (Hologic QDR Discovery, Bedford, MA, USA). This value is really important to determine a cardiovascular risk. | Baseline | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Klotho, Exercise, Physical Fitness