Using Multimedia Approaches to Communicate Probabilities in Patient Decision Aids for Low-Literacy Populations: Randomized Trial

Study Overview
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Brief Summary
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The goal of this research study is to compare how people who are 45-75 years old respond to 3 different versions of a program about screening tests for colorectal cancer. Researchers want to use this study as part of a long-term project to learn the best ways to communicate health information to patients.

Detailed Description
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If you agree to take part in this study, you will be randomly assigned (as in a roll of dice) to 1 of 3 study groups. Neither you nor the study staff will be able to choose which group you will be in: If you are in Group 1, you will read a booklet about colorectal cancer screening tests. While reading the booklet, you will also listen to an audio CD that will narrate the booklet. If you are in Group 2, you will watch a video with non-moving images about colorectal cancer screening tests on an iPad. If you are in Group 3, you will watch a video with animated images about colorectal cancer screening tests on an iPad. You will complete questionnaires before and after viewing the program that will contain questions about: Your age and what language you speak Your math and reading comprehension Your knowledge of colorectal cancer and colorectal cancer screening Your thoughts about colorectal cancer screening Your opinions about this study, and How well you understand the booklet/video you view as part of this study It will take about 1 hour to complete all the questionnaires. In total, the study will take about 1 ½ to 2 hours to complete. After you have completed the questionnaires, your participation in the study will be over. This is an investigational study. Up to 201 people will take part in this multicenter study. Up to 67 will be enrolled at MD Anderson.

Official Title
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Using Multimedia Approaches to Communicate Probabilities in Patient Decision Aids for Low-Literacy Populations: Randomized Trial

Conditions
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Colorectal Cancer

Intervention / Treatment
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* Behavioral: Booklet
* Behavioral: Audio CD
* Behavioral: Video with Non-Moving Images
* Behavioral: Video with Animated Images
* Behavioral: Questionnaires


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Men and women 45 to 75 years of age. Participant must speak English. Exclusion Criteria: 1) Self-reported diagnosis of colon cancer.

Ages Eligible for Study
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Minimum Age: 45 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Colorectal Cancer Screening Booklet + Audio CD<br>Participants read the booklet about colorectal cancer screening tests, and listen to an audio CD that will narrate the booklet. Questionnaire completion before and after viewing the program. | Behavioral: Booklet<br>* Participants read a booklet about colorectal cancer screening tests.<br>* Other names: Pamphlet;Behavioral: Audio CD<br>* Participants listen to an audio CD that will narrate the colorectal cancer screening tests booklet.<br>Behavioral: Questionnaires<br>* Questionnaire completion before and after viewing the program.<br>* Other names: Surveys;|
| Video with Non-Moving Images on iPad<br>Participants watch a video with non-moving images about colorectal cancer screening tests on an iPad. Questionnaire completion before and after viewing the program. | Behavioral: Video with Non-Moving Images<br>* Participants watch a video with non-moving images about colorectal cancer screening tests on an iPad.<br>Behavioral: Questionnaires<br>* Questionnaire completion before and after viewing the program.<br>* Other names: Surveys;|
| Video with Animated Images on iPad<br>Participants watch a video with animated images about colorectal cancer screening tests on an iPad. Questionnaire completion before and after viewing the program. | Behavioral: Video with Animated Images<br>* Participants watch a video with animated images about colorectal cancer screening tests on an iPad.<br>Behavioral: Questionnaires<br>* Questionnaire completion before and after viewing the program.<br>* Other names: Surveys;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Gist and Verbatim Knowledge for a Colorectal Cancer Screening Program | The fixed effects analysis of variance (ANOVA) will utilize a factorial design with two factors: content presentation type (standard, animated, interactive) and numeracy status (high and low based on US population scores). Main dependent measures are gist and verbatim knowledge. Gist and verbatim knowledge scores (0-100) looked at separately as well as combined. | 1 day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Colorectal Cancer, Colorectal cancer screening, Multimedia, Booklet, Pamphlet, Audio CD, Video with animated images, Video with non-moving images, Questionnaires, Surveys