Comparison Between Local and Imported Skin Prick Testing Result of Rat and Mouse Allergen Extracts

Study Overview
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Brief Summary
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In respiratory allergy patients, skin prick test results of local rat and mouse allergen extracts are not significant different from imported ones

Detailed Description
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Many researches proposed that rodent deteriorate symptoms in patients with respiratory allergy who sensitized. The test that can identify rodent sensitization will be very useful. The investigators found lots of problems from imported mouse and rat allergen extract, eg. expensive cost and hard to find importing agency in Thailand. Making own local allergen extract will be the good solution for the country. This study aim to compare the results of locally rat and mouse allergen to imported ones.

Official Title
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Comparison Between Local and Imported Skin Prick Testing Result of Rat and Mouse Allergen Extracts in Respiratory Allergy Patients

Conditions
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Allergic Rhinitis Due to Animal Hair and Dander

Intervention / Treatment
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* Diagnostic Test: rat and mouse skin test


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients age 3 to 60 years old who diagnosed with asthma or allergic rhinitis Patient must not take these following medication at least 7 days before doing the skin prick test: antihistamine, oral corticosteroid (more than 20 mg/day of prednisolone), topical steroid that was apply on skin test area. Exclusion Criteria: Pateints who have other chronic underlying disease e.g. obesity, heart disease and liver disease Patient with allergic asthma who is still uncontrollable. Patient with active severe atopic dermatitis Patient who are pregnant or in lactating period Patient or parent deny to join in the study

Ages Eligible for Study
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Minimum Age: 3 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Local rat and mouse skin test<br>All patients receive local skin prick test for mouse and rat. The result were recorded and compared to the imported one. | Diagnostic Test: rat and mouse skin test<br>* Comparison between local and imported skin prick testing result of rat and mouse allergen extracts in respiratory allergy patients<br>|
| Active Comparator: Imported rat and mouse skin test<br>All patients receive imported skin prick test for mouse and rat. The result were recorded and compared to the local one. | Diagnostic Test: rat and mouse skin test<br>* Comparison between local and imported skin prick testing result of rat and mouse allergen extracts in respiratory allergy patients<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Comparison between local and imported skin prick testing result of rat and mouse allergen extracts in respiratory allergy patients | Compare the results of locally rat and mouse allergen to imported ones. | 1 year |