OSTAP Versus TAP for Postoperative Pain Management in Laparoscopic Cholecystectomy Patients

Study Overview
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Brief Summary
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The aim of the study is to compare the effectiveness and opioid sparing effects of TAP and OSTAP in patients undergoing laparoscopic cholecystectomy.

Detailed Description
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Patients undergoing laparoscopic cholecystectomy were separated into 3 groups. Group 1: Received TAP block Group 2: Received OSTAP Group 3: No Block Standard General Anesthesia was induced and maintained in all patients. At the end of the operation patient controlled analgesia with morphine was applied to all patients. Pain scores were evaluated at 0,2,4,6,12,24 hours postoperatively. Total morphine consumption and pain scores were compared.

Official Title
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The Comparison of Analgesic Sparing Effects of Oblique Subcostal Transversus Abdominis Plane Block (OSTAP) and Transversus Abdominis Plane Block (TAP) in Patients Undergoing Laparoscopic Cholecystectomy

Conditions
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Pain Postoperative

Intervention / Treatment
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* Procedure: TAP
* Procedure: OSTAP


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Scheduled for laparoscopic cholecystectomy ASA status I-II Exclusion Criteria: Local anesthetic allergy Coagulopathy Infection at procedure site

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Group 1: TAP Block<br>TAP Block performed from the petit triangle ( anterior axillary line and iliac crest.) | Procedure: TAP<br>* Classic TAP block performed through the petit triangle (the anterior axillary line and iliac crest)<br>|
| Active Comparator: Group 2: OSTAP Block<br>Modified TAP (OSTAP) block performed from the medial of linea semilunaris applying local anesthetic to the area between xiphoid and anterior iliac crest. | Procedure: OSTAP<br>* Modified TAP (OSTAP) block performed from the medial of linea semilunaris applying local anesthetic to the area between xiphoid and anterior iliac crest.<br>|
| No Intervention: No Block<br>No interventions | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in postoperative pain scores throughout time evaluated by VAS | Pain scores are going to be evaluated via VAS score. The VAS score will be scored between 0-10. 0 points is defined as no pain and 10 points is the most severe pain imaginable by the patient. A higher VAS score reflects a poor pain control. | Pain scores will be recorded for 24 hours postoperatively. The first measure will be taken immediately after surgery (time 0) and then at 2. 4. 6. 12. 24. hours. | 
| Change in opioid Sparing effect measured through morphine amount delivered by a patient controlled analgesia device. | The amount of morphine demand of the patient measured through morphine delivery by the patient controlled analgesia device | The amount of Morphine demanded by the patient will be recorded for 24 hours postoperatively. The first measure will be taken immediately after surgery (time 0) and then at 2. 4. 6. 12. 24. hours. | 
| Amount of total intraoperative remifentanil infusion | The total amount of infused remifentanil throughout the surgery will be recorded from the infusion device. | At the end of surgery. | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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TAP OSTAP Postoperative pain