Ultrasound Guided Rhomboid Intercostal and Subserratus Plane Block in Breast Cancer Surgeries

Study Overview
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Brief Summary
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Postoperative analgesia after breast cancer surgery is a challenge for anesthesiologists due to the complex innervation of the breast. Interfascial plane blocks of the chest are gaining widespread popularity with the introduction of ultrasonography into the regional anesthesia practice. We aimed to investigate the efficacy of Rhomboid intercostal and subserratus plane block (RISS) for postoperative analgesia in patients undergoing breast cancer surgery.

Detailed Description
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This prospective randomized controlled trial will be carried out on female patients who scheduled for breast cancer surgery. Our hypotesis is that this new interfascial plane block technique will able to provide postoperative analgesia in breast cancer surgery.

Official Title
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Ultrasound Guided Rhomboid Intercostal and Subserratus Plane Block in Breast Cancer Surgeries

Conditions
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Breast Cancer Surgery, Postoperative Analgesia

Intervention / Treatment
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* Drug: Rhomboid Intercostal and Subserratus Plane Block with local anesthetic


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Female patients aged 18-85 years and ASA physiological score I-III who undergone breast cancer surgery Exclusion Criteria: Patients refused to participate. Patients with known or suspected allergy to the used medication. Patients with psychiatric-neurological disorders that may affect pain perception, Patients regularly taking antipsychotics and antidepressants. Patients with potential risk of coagulopathy. Uncooperative patients.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Prospective study
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Group Rhomboid Intercostal and Subserratus Plane Block<br>In addition to routine standard perioperative and postoperative analgesic protocol participants will recieve Rhomboid Intercostal and Subserratus Plane Block under ultrasound guidence at the end of the surgery. | Drug: Rhomboid Intercostal and Subserratus Plane Block with local anesthetic<br>* Local anesthetic will be injected in the tissue planes between the rhomboid and the intercostal muscles and the serratus anterior and external intercostal muscles with ultrasound guidence.<br>* Other names: 40 mL of bupivacaine/lidocaine mixture;|
| No Intervention: Control Group<br>Routine standard perioperative and postoperative analgesic protocol will be given. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative opiod consumption | Opioid consumptions for both group will be recorded. | The first 24 hours postoperatively | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative pain scores | Postoperative pain will be assessed using a Numeric Rating Scale (NRS) ranging from 0 (no pain) to 10 (worst imaginable pain).The NRS will be recorded in postoperative unit and in ward at first hour and at 2th, 6th, 12th and 24 th hour. | The first 24 hours postoperatively | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Rhomboid intercostal and subserratus plane block