Ultrasound Guided Axillary Versus Jugular Central Venous Catheterization

Study Overview
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Brief Summary
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The main intention of this study is to compare two ultrasound-guided central venous catheterization procedures namely: real-time, ultrasound-guided, in plane axillary vein catheterization and real-time, ultrasound-guided, out of plane jugular vein catheterization in terms of venipuncture, catheterization success, early mechanical complication and catheter-related infection rate in mechanically ventilated patients admitted to the intensive care unit.

Official Title
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Real-time Ultrasound-guided Axillary and Jugular Vein Catheterization: A Prospective Comparison in Mechanically Ventilated Critically Ill Patients. A Randomized Study

Conditions
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Critical Illness

Intervention / Treatment
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* Procedure: Real-time ultrasound-guided central vein catheterization.


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: mechanically ventilated intensive care patients with clinical indications for central venous line placement Exclusion Criteria: trauma and hematoma at the catheterization site major blood coagulation disorders coincided with active bleeding anatomical abnormalities at the catheterization site infection at the catheterization site age less than 18 years lack of patients or closest relatives consent

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Axillary catheterization<br>Real-time ultrasound-guided axillary vein catheterization, in plain technique. | Procedure: Real-time ultrasound-guided central vein catheterization.<br> <br> |
| Experimental: Jugular catheterization<br>Real-time ultrasound-guided jugular vein catheterization, out of plain technique. | Procedure: Real-time ultrasound-guided central vein catheterization.<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Procedure success rate | to define catheterization success rate | 24 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of Catheter colonization | to assess the incidence of catheter colonization after removal | 1 month | 
| Incidence of catheter-related bloodstream infection | to assess the incidence of catheter-related bloodstream infection | 1 month | 
| Procedure complication rate | to assess the early mechanical complication rate | 24 hours | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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ultrasonography, catheterization, central line, mechanical ventilation, intensive care, axillary vein, jugular vein, randomization