Genetic Information and Dietary Intake Behaviour

Study Overview
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Brief Summary
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This study's primary objective is to determine if providing individuals with personal genetic information impacts dietary intake behaviour. Specifically, the investigators will be examining whether providing dietary advice based on genes that affect the metabolism of or sensitivity to caffeine, vitamin C, sugar and sodium will impact the intake of these dietary components. The study hypothesis is that providing dietary advice based on genetics will impact dietary behaviour to a greater extent than general dietary recommendations.

Official Title
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Genetic Information and Dietary Intake Behaviour

Conditions
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Healthy

Intervention / Treatment
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* Other: Dietary advice with genetic information
* Other: General dietary recommendations


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 20-35 year old participants from the Toronto Nutrigenomics and Health Study Exclusion Criteria: pregnancy or nursing vitamin C supplement users caffeine intake < 100 mg/day total sugars intake < 10% energy sodium intake < 1500 mg/day

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 35 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Dietary advice with genetic information<br>This group will receive dietary advice for caffeine, vitamin C, sugar and sodium based on genetic information. | Other: Dietary advice with genetic information<br>* This group will receive dietary advice for caffeine, vitamin C, sugar and sodium based on genes that affect the metabolism of or sensitivity to caffeine, vitamin C, sugar and sodium.<br>|
| Active Comparator: General dietary recommendations<br>This group will receive general dietary recommendations for caffeine, vitamin C, sugar and sodium from recognized health institutions (caffeine: Health Canada; sugar: the World Health Organization; vitamin C and sodium: the Institute of Medicine). | Other: General dietary recommendations<br>* This group will receive general dietary recommendations from recognized health organizations for caffeine, vitamin C, sugar and sodium, with no genetic information.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change from Baseline in Dietary Intake at 3 months | We will assess dietary intakes of caffeine (mg), vitamin C (mg), sugar (g and % energy) and sodium (mg) using Food Frequency Questionnaires (FFQ). An FFQ will be administered at baseline to determine dietary habits before dietary advice is given to either group (control or intervention). A second FFQ will be administered 3 months after the dietary advice is given, to examine if any changes were made to dietary intake in the short-term. | 3 months | 
| Change from Baseline in Dietary Intake at 12 months | A third FFQ will be administered 12 months after the dietary advice is given, to examine if any long-term dietary changes were made in intakes of caffeine (mg), vitamin C (mg), sugar (g and % energy) and sodium (mg). | 12 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Nutrigenomics, Diet, Nutrition