Depression Prevention Program for Adolescents

Study Overview
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Brief Summary
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This study will compare the effectiveness of two programs designed to prevent depression in adolescents.

Detailed Description
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Major depression is one of the most common psychiatric disorders in adolescents. In many cases, the condition is recurrent and can result in serious psychological impairment. A high number of depressed adolescents never receive treatment; therefore, it is crucial to develop prevention programs for this disorder that are effective and can be easily disseminated. This study will evaluate and compare the effectiveness of cognitive behavior therapy (CBT) and supportive/expressive (S/E) therapy in preventing depressive symptoms in adolescents. This study will last 2 years. Participants will be randomly assigned to receive six sessions of CBT, S/E therapy, or standard depression education over 2 years. The CBT intervention will focus on reducing negative thoughts and increasing engagement in pleasant activities. S/E therapy is designed to allow adolescents to express their negative emotions and talk about recent stressful events in a supportive environment of their peers. Surveys and psychiatric interviews will be completed by all participants and their parents at the beginning and the end of the study. The surveys and interviews will assess depressive symptoms.

Official Title
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Depression Prevention Program for High-Risk Adolescents

Conditions
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Depression

Intervention / Treatment
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* Behavioral: Cognitive behavior therapy (CBT)
* Behavioral: Supportive/expressive (S/E) therapy
* Behavioral: Bibliotherapy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Beck Depression Inventory score higher than 10 Parent or guardian willing to provide informed consent Exclusion Criteria: Diagnosis of depression

Ages Eligible for Study
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Minimum Age: 14 Years
Maximum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 1<br>Participants will receive cognitive behavioral therapy | Behavioral: Cognitive behavior therapy (CBT)<br>* Participants will complete worksheets and group discussion on how to increase positive mood and activity.<br>|
| Active Comparator: 2<br>Participants will receive supportive/expressive therapy | Behavioral: Supportive/expressive (S/E) therapy<br>* Participants will be encouraged to express feelings and emotions without advice giving.<br>|
| Active Comparator: 3<br>Participants will receive bibliotherapy | Behavioral: Bibliotherapy<br>* Participants will be given a book on how to increase their mood.<br>|
| No Intervention: 4<br>Participants in the control condition will receive no treatment | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Depressive symptoms |  | Measured at Year 1 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Adolescent, CBT