Light-induced Effects on Dental Implant Stability

Study Overview
=================
Brief Summary
-----------------
Until now, limited research has observed the stability of photo functionalized sandblasted acid-etched (SLA) titanium implants. The study includes a sample size of sixty otherwise healthy patients with implant replacement, comparing nonirradiated, irradiated UVA and UVC titanium implants. It was an interventional study with a sample size divided into three groups using simple randomization. Patients with nonirradiated dental implants make the control group A with UVA and UVC dental implants forming groups B and C, respectively. Before functional loading, implant stability was measured on days zero and eight weeks. SPSS 26.0 is used for data analysis. The data for implant stability quotient (ISQ) levels and osseointegration speed index (OSI) were presented as mean ± SD for each group. The effect of UVA and UVC on ISQ2 compared with the baseline ISQ was done by applying multiple simple regression analysis models, whereas the distinction between UVA and UVC was made through a t-test. p ≤ 0.05 was kept statistically significant. The implants irradiated with UVA significantly affected ISQ levels compared to other groups.

Official Title
-----------------
Ultraviolet A and Ultraviolet C Light-induced Effects on Dental Implant Stability

Conditions
-----------------
Missing Teeth

Intervention / Treatment
-----------------
* Procedure: photofunctionalization


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: systemically healthy patients with age > 20 with at least one tooth or more missing Exclusion Criteria: -

Ages Eligible for Study
-----------------
Minimum Age: 21 Years
Maximum Age: 60 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: Non irradiated implants (group A)<br> | |
| Active Comparator: UVA irradiated group (group B)<br> | Procedure: photofunctionalization<br>* UVA and UVC photofunctionalization of dental implants<br>|
| Active Comparator: UVC irradiated group (group C)<br> | Procedure: photofunctionalization<br>* UVA and UVC photofunctionalization of dental implants<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| ISQ measurement through Ostelltm Mentor device | The Ostelltm device was initially calibrated using a test peg called the ISQ. A smart peg was used for assessment. The smart peg tightened with 5 Ncm torque is then mounted on implant fixture and the transducer connected perpendicular to the implant . The measuring probe is brought closer to the smart peg without touching it. A beeping sound displays the reading on the monitor. Two successive readings are taken mesiodistally along the jaw and buccolingually perpendicular to the jaw .The RFA measurements taken twice during implant treatment are recorded. All the ISQ values were recorded from one to hundred and a mean was taken. | eight months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
dental implants