Surgical Approach in Liver Hemangiomas

Study Overview
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Brief Summary
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Operations performed for liver hemangioma between January 2017 and December 2018 will be retrospectively analyzed.

Detailed Description
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Operations performed for liver hemangioma at Ankara University Hospitals will be retrospectively analyzed. Patient and disease characteristics including demographics, laboratory tests, imaging studies, type of surgical approach and outcomes including postoperative laboratory tests, record of complications, duration of hospital stay will be reviewed. Complications were classified according to Clavien-Dindo classification. The patients were informed about the surgeries in advance and their informed consents about surgeries and data collection for scientific purposes were obtained. Datafile will be anonymized before analysis and original file will be destroyed. Outcomes such as complications, hospital stay, blood transfusion and mortality will be compared between groups created according to type of surgery, lesion size, preoperative laboratory values and demographic features. Variables for prediction of better outcomes are expected to be discovered.

Official Title
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Surgical Approach in Liver Hemangiomas With Special Emphasis on Lesion Diameter and Type of Surgery

Conditions
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Hemangioma Liver

Intervention / Treatment
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* Procedure: Liver resection or enucleation for liver hemangioma


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients underwent surgery for liver hemangioma Exclusion Criteria: Cases lacking of more than 20% of critical data

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: Liver resection or enucleation for liver hemangioma|Operations in which the hemangioma is selectively removed from the liver parenchyma border are named enucleation, and the operations in which the hemangioma is removed anatomically or non-anatomically with some liver parenchyma surrounding it are named liver resection|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Complications | Complications after surgery for hemangioma will be collected from records and and will be classified according to 'The Clavien-Dindo Classification of Surgical Complications'. The classification grades are ranging between Grade 1(better) which indicates minor deviation from normal postoperative course and Grade 5 (worst) which means death as a complication. | Complications reported within 3 months after surgery will be evaluated within 15 days after completion of data collection | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Hospital stay | Length of hospital stay postoperatively | Hospital stay starting with operation and ends with discharge will be compared within 15 days after completion of data collection | 
| Transfusion | Rate of erythrocyte transfusion | Erythrocyte transfusion during surgery will be analyzed within 15 days after completion of data collection | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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hemangioma, liver resection, enucleation