An Iliopsoas Plane Block After Total Hip Arthroplasty

Study Overview
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Brief Summary
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Nielsen et al. reported that when iliopsoas plane block was performed on healthy volunteers, the injection solution in Hip MRI was confined to the myofascial compartment, which was known to include all sensory branches of the femoral nerve that control the hip joint. The maximal muscle strength of knee extension did not decrease before and after Iliopsoas plane block in Volunteer. Since there is no clinical study conducted on patients after the volunteer study, the investigators intend to evaluate the analgesic and motor preserving effects of the iliopsoas plane block in a group of patients undergoing total hip arthroplasty.

Official Title
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An Iliopsoas Plane Block for Pain Management After Total Hip Arthroplasty: a Randomized Controlled Trial

Conditions
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Total Hip Arthroplasty

Intervention / Treatment
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* Procedure: iliopsoas plane block group
* Procedure: sham block group


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients 19 years of age or older who are expected to undergo unilateral hip arthroplasty ASA PS 1-3 Exclusion Criteria: Revision total hip arthroplasty Allergy to drugs used in the study Patients with moderate or more hepatic impairment (AST/ALT is more than 2.5 times the upper limit of normal) Estimated glomerular filtration rate < 30 mL/min/1.73m2 Opioid dependence Prolongation of PT and aPTT more than twice the upper limit of normal Pre-existing neurological or anatomical disorders of the lower extremities Serious psychiatric disorders

Ages Eligible for Study
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Minimum Age: 19 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Parallel assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: liopsoas plane block group<br>Arm Description: a iliopsoas plane block before surgery | Procedure: iliopsoas plane block group<br>* Ultrasound-guided iliopsoas plane block with 0.75% ropivacaine 10 ml and epinephrine 0.05 ml (1:200,000) 10 ml<br>|
| Sham Comparator: sham block group<br>sham block before surgery | Procedure: sham block group<br>* Ultrasound-guided iliopsoas plane block with normal saline 10 ml<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Numeric rating scale pain score at rest | Pain intensity at rest will be evaluated by an 11-point numeric rating scale (NRS: 0 = no pain, 10 = worst imaginable pain) 1, 6, 24, and 48 hours after the surgery. | up to 48 hours after the surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Numeric rating scale pain score at movement | Pain intensity during 45-degree passive flexion of the hip with the ipsilateral knee flexed naturally will be evaluated by an 11-point numeric rating scale (NRS: 0 = no pain, 10 = worst imaginable pain) 1, 6, 24, and 48 hours after the surgery. | up to 48 hours postoperatively | 
| Postoperative opioid consumption | morphine equivalent dose | postoperative 24, 48hours |