Ten Years Follow up of Peri-implant Surgery

Study Overview
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Brief Summary
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To report 10-years follow up of patients following the surgical treatment of peri-implantitis and to identify possible risk indicators for the progression of disease during supportive peri-implant therapy.

Detailed Description
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The data for this retrospective clinical evaluation were collected from the files and radiographs of consecutive patients who had received surgical treatment of peri-implantitis between 2007 and 2009 and thereafter enrolled in supportive peri-implant treatment (SPT) . Between 2007 and 2009, 41 patients with at least 1 implant with peri-implantitis that underwent peri-implant surgery were enrolled in a supportive peri-implant therapy. At the 2-years follow up, two groups could be identified, one responding group (17 patients) who did not present any implants with peri-implantitis and a no-responding Group (22 patients), presenting still peri-implantitis. Following the 2-years control visit, 17 patients of the responding group exited the supporting peri-implant therapy at the specialist clinic. They continued the routine controls at their referral clinics while the 22 patients of the no-responding group, continued the scheduled supportive peri-implant therapy (SPT) given at the specialist clinic.

Official Title
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10 Years Follow-up of Patients With Residual Pockets Following the Surgical Treatment of Peri-implantitis

Conditions
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Peri-Implantitis

Intervention / Treatment
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* Other: Descriptive study


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: - All patients treated with peri-implantitis surgery between 2007 and 2009 using an anti-infective protocol. Exclusion Criteria: Patients treated with peri-implantitis surgery between 2007 and 2009 using a regenerative protocol at one single implants with peri-implantitis.
Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Descriptive study|Evaluation of routine treatment|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number patients with persisting peri-implantitis following peri-implant surgery | The total number of patients with persisting peri-implantitis will be calculated. Any subject presenting at least one implants with a pathological pocket will be regarded as positive for the disease . The presence or absence of peri-implantitis will be assessed by using a periodontal probe around the mucosa of the implants. The definition of a pathological pocket around an implant is a pocket of 5 millimeters or more deep with concomitants bleeding after the use of the probe. | 10 years | 
| Percentage of subjects with persisting peri-implantitis | The percentage of patients with persisting peri-implantitis following peri-implantitis surgery will be calculated among all the patients that were treated. For definition of peri-implantitis see description at outcome 1. | 10 years | 
| Number of implant with persisting peri-implantitis | The number of implants with persisting clinical signs of peri-implantitis will be calculated. Any implant presenting a pathological pockets around its surface will be regarded as positive for the disease. For definition of peri-implantitis see description at outcome 1 | 10 years | 
| Percentage of implants wih persisting peri-implantitis | The percentage of implants with persisting peri-implantitis after surgery will be calculated among all the implants that were surgically treated. For definition of peri-implantitis see description at outcome 1 | 10 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Assessement of risk factors related to the persistence of peri-implantitis | A univariate logistic regression to assess the correlations between each independent variable and the binary outcome presence or absence of peri-implantitis at treated implants will be used. Then, a multivariable regression analysis will be use including the independent variables from the univariate analysis that reach a statistical significance after adjusting for gender and age. | 10 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Peri-Implantitis surgery, Treatment outcome, Risk factors