Promoting Altruism to Enhance Vaccine Acceptance

Study Overview
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Brief Summary
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Subjects enrolled in this study are eligible for the seasonal influenza vaccine. The purpose of this research study is to figure out if increasing individuals' awareness of the benefits of herd immunity, specifically to the local pediatric oncology community, can improve vaccination uptake rates.

Detailed Description
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The purpose of this study is to identify associations with influenza vaccine hesitancy, including parental demographics and altruism score, in families with healthy children attending two pediatric practices. Also, in the cohort of families with baseline vaccine hesitancy, to assess the effectiveness of a pilot educational intervention focusing on the development of herd immunity for pediatric oncology patients by measuring: The change in vaccine hesitancy scores pre- and post-intervention. The rate of influenza vaccine uptake compared to historic controls from previous influenza seasons. Another aim is to explore the relationship between baseline influenza vaccine hesitancy rates and baseline altruism scores. Effectiveness of this intervention is dependent on parental altruism levels; therefore, the study team also seeks to determine if there is an association between parental altruism and vaccine hesitancy for their children. This is a single-arm prospective cohort study. The study will enroll legal guardians of children who are influenza vaccine-eligible to measure their vaccine hesitancy scores, altruism scores, and the impact of an educational intervention focused on herd immunity on the guardians' vaccine hesitancy score.

Official Title
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Cohort Study to Determine the Effect of an Educational Intervention Focusing on Herd Immunity to Enhance Vaccination Uptake Rates

Conditions
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Vaccine Refusal

Intervention / Treatment
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* Behavioral: educational intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All legal guardians of children aged 6 months and up who are influenza vaccine-eligible and present to the pediatric clinic. Exclusion Criteria: Legal guardians of children who are not influenza vaccine-eligible including children less than 6 months of age, children on immunosuppressive medications, and children with underlying medical conditions resulting in an immunocompromised state.
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Vaccine Hesitant<br>Subjects who consent to this study and deemed vaccine hesitant, they will receive an educational intervention. | Behavioral: educational intervention<br>* If the guardian screens positive for vaccine hesitancy (i.e., vaccine hesitancy score average > 3), they will be given the informational handout along with a brief script.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Vaccine Hesitancy Scores Pre- and Post-Intervention. | 8-item Vaccine Hesitancy Scale. Subjects identified as vaccine-hesitant based on a Vaccine Hesitancy Score >/= 3. Score range is 1-5 and > or = 3 is considered vaccine hesitant. | baseline | 
| Pre-Intervention Vaccine Hesitancy Score | 8-item Vaccine Hesitancy Scale. Subjects identified as vaccine-hesitant based on a Vaccine Hesitancy Score >/= 3. Score range is 1-5 and > or = 3 is considered vaccine hesitant. | baseline | 
| Post-Intervention Vaccine Hesitancy Score | 8-item Vaccine Hesitancy Scale. Subjects identified as vaccine-hesitant based on a Vaccine Hesitancy Score >/= 3. Score range is 1-5 and > or = 3 is considered vaccine hesitant. | baseline | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rate of Influenza Vaccine Uptake | The subject's child's electronic health record will be accessed to document whether that patient received the seasonal influenza vaccine during the baseline visit. | baseline | 
| Pre-Intervention Altruism Scale | Scale ranges from 20-100 with a higher score denoting higher altruism. | baseline | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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altruism, vaccine acceptance, flu vaccine