Effect of Exercise on Risk-factors of Elderly Women

Study Overview
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Brief Summary
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The purpose of this study is to determine whether exercise training may impact relevant risk factors and health costs of community living women older 65 years.

Detailed Description
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The human aging process is associated with a significant increase of risk factors (i.e. osteoporosis, coronary heard disease, diabetes) and a decline in neuromuscular function impacting independence of the subject. Osteoporosis, diabetes type II and arteriosclerosis are diseases known to correlate with age. Participating in regular sport activities elicits numerous favorable effects that contribute to healthy aging. Unfortunately all existing studies which focus on specific diseases or conditions favour dedicated exercise regimes. However, the complex risk factor scenario of older adults requires multi-purpose exercise programs with impact on all relevant risks. Furthermore so far no exercise study longitudinally determines the effect of an ambulatory exercise program on health cost considering the specific health policy framework of Germany. We hypothesize that regular exercise significantly impact relevant osteoporosis, cardiovascular diseases and diabetes risk factors in elderly subjects significantly reduces health costs in elderly community living women

Official Title
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Effects of Exercise on Multiple Risk Factors and Health Costs in Community Living Elderly Women. The Senior Fitness and Prevention Study (SEFIP)

Conditions
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Atrophy

Intervention / Treatment
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* Behavioral: physical exercise, wellness


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Community living Caucasian woman ≥ 65 years; live expectation > 2 years Exclusion Criteria: secondary osteoporosis CVD-events including stroke Participation in other studies Medication with impact on bone during the last 2 years: bisphosphonates parathormone strontium HRT, anabolic steroids calcitonin natriumflourides active Vit-D-metabolites cortisone > 5 mg/d medication with impact on falls low physical performance (<50 Watt during ergometry) excessive alcohol-intake

Ages Eligible for Study
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Minimum Age: 65 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: physical exercise, wellness|nan|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| health costs after 18 months |  | baseline 18 month control | 
| falls after 18 months |  | daily records, analysis after 18 months | 
| Bone parameters after 6, 12 and 18 months |  | baseline, 6, 12, 18 month-control | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Functional status after 6, 12, and 18 months |  |  | 
| CHD- and diabetes-risk-factors (bodyfat, blood lipids, glucose, blood pressure) after 6, 12 and 18 months |  |  | 
| Quality of live after 12 and 18 months |  |  | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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exercise, intervention, elderly woman, risk factors, health costs, Osteoporosis, cardiovascular diseases, diabetes, Higher Age