Mayo Clinic IBD Biobank

Study Overview
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Brief Summary
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Researchers are collecting and storing blood, stool, and urine samples and medical information to better understand Inflammatory Bowel Disease (IBD) to improve disease outcome.

Detailed Description
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Subjects will be sent a letter detailing the proposed biobank and soliciting enrollment. Following the informed consent process, subjects will provide a blood sample (50 ml), urine sample (50 ml), and stool. The blood and urine samples will either be collected at the one of the Mayo Clinic outpatient laboratories or by a mail-out kit. Subjects will be asked to complete a questionnaire and 24-hour food recall questionnaire (completed online).

Official Title
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Mayo Clinic IBD Biobank

Conditions
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Inflammatory Bowel Diseases

Intervention / Treatment
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* Procedure: Blood Draw
* Procedure: Urine Collection
* Procedure: Stool Collection


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients diagnosed with inflammatory bowel disease (IBD) who are between the ages of 18 and 85 at time of study enrollment. The diagnosis of IBD will be based on the standard IBD criteria including biochemical and colonoscopy screening. Women with inflammatory bowel disease of childbearing potential and pregnant women will be offered enrollment because there is no risk to an unborn child in this investigation. Patients between the ages of 18 and 85 without history of IBD or colon cancer. Exclusion Criteria: Patients with known liver disease. Patients unable to provide informed consent. Prisoners and institutionalized individuals. Patients with a history of colorectal cancer.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Control Group<br>Subjects without inflammatory bowel disease (IBD) will have samples collected of blood, urine and stool | Procedure: Blood Draw<br>* 50 ml will be collected<br>Procedure: Urine Collection<br>* 50 ml will be collected<br>Procedure: Stool Collection<br>* Three 25 ml tubes will be collected<br>|
| Inflammatory bowel disease (IBD)<br>Subjects with known inflammatory bowel disease will have samples collected of blood, urine and stool | Procedure: Blood Draw<br>* 50 ml will be collected<br>Procedure: Urine Collection<br>* 50 ml will be collected<br>Procedure: Stool Collection<br>* Three 25 ml tubes will be collected<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Study Participants | Total number of participants in the study | 50 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Urine Collection | Total number of urine samples collected | 50 years | 
| Blood Collection | Total number of blood samples collected | 50 years | 
| Stool Collection | Total number of stool samples collected | 50 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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IBD, Ulcerative colitis, Crohn's