SWOG-9245 Collecting and Storing Tissue Samples From Patients With Relapsed or Recurrent Non-Hodgkin Lymphoma After Treatment on a Southwest Oncology Group Clinical Trial

Study Overview
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Brief Summary
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RATIONALE: Collecting and storing samples of tissue from patients with non-Hodgkin lymphoma to study in the laboratory may help the study of cancer in the future. PURPOSE: This laboratory study is collecting and storing tissue samples from patients with relapsed or recurrent non-Hodgkin lymphoma after treatment on a Southwest Oncology Group (SWOG) clinical trial.

Detailed Description
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OBJECTIVES: Acquire fresh snap-frozen lymphoma tissue from patients with relapsed or recurrent non-Hodgkin lymphoma after treatment on a Southwest Oncology Group (SWOG) clinical trial. Establish a standard set of procedures for routine acquisition, banking, and study of lymphoma tissues within the SWOG. Use repository tissue to establish clinical correlations via presently activated phenotyping studies and future projected molecular studies assessing specimen DNA and RNA status. Examine the biology of therapy failure in relationship to changes in pretreatment and post-treatment immunophenotypic data. OUTLINE: This is a multicenter study. Tissues collected at biopsy are snap-frozen and archived for future molecular and genetic studies. PROJECTED ACCRUAL: Not specified

Official Title
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Central Lymphoma Repository Tissue Procurement Protocol for Relapse or Recurrent Disease

Conditions
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Lymphoma

Intervention / Treatment
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* Other: cryopreservation


Participation Criteria
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Eligibility Criteria
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DISEASE CHARACTERISTICS: Diagnosis of relapsed or recurrent non-Hodgkin lymphoma (NHL) Previously registered on 1 of the following SWOG clinical trials for previously untreated NHL: SWOG-8410 SWOG-8503 SWOG-8508 SWOG-8516 SWOG-8736 SWOG-8809 SWOG-8907 SWOG-8954 SWOG-9125 SWOG-9240 SWOG-9320 SWOG-9349 SWOG-9432 SWOG-9501 SWOG-9703 SWOG-S9704 SWOG-9800 Tissue samples of relapsed or recurrent disease available PATIENT CHARACTERISTICS: Not specified PRIOR CONCURRENT THERAPY: See Disease Characteristics

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: cryopreservation|nan|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Acquisition of snap-frozen lymphoma tissues |  | July 2011 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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recurrent grade 3 follicular lymphoma, recurrent adult diffuse small cleaved cell lymphoma, recurrent adult diffuse mixed cell lymphoma, recurrent adult diffuse large cell lymphoma, recurrent adult immunoblastic large cell lymphoma, recurrent adult lymphoblastic lymphoma, recurrent adult Burkitt lymphoma, recurrent adult grade III lymphomatoid granulomatosis, recurrent grade 1 follicular lymphoma, recurrent grade 2 follicular lymphoma, recurrent mantle cell lymphoma, recurrent marginal zone lymphoma, recurrent small lymphocytic lymphoma, extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue, nodal marginal zone B-cell lymphoma, splenic marginal zone lymphoma, Waldenström macroglobulinemia, adult nasal type extranodal NK/T-cell lymphoma, recurrent childhood grade III lymphomatoid granulomatosis, recurrent childhood large cell lymphoma, recurrent childhood lymphoblastic lymphoma, recurrent childhood small noncleaved cell lymphoma, childhood diffuse large cell lymphoma, childhood immunoblastic large cell lymphoma, childhood Burkitt lymphoma, childhood nasal type extranodal NK/T-cell lymphoma