Sarcopenia And Balance In Postmenopausal Osteoporosis

Study Overview
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Brief Summary
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The study was performed on 53 postmenopausal osteoporosis patients who presented to our osteoporosis outpatient clinic. Following written informed consent, patients were evaluated for sarcopenia according to the sarcopenia algorithm proposed by the European Working Group on Sarcopenia in Older People (EWGSOP). Algorithm parameters were walking speed, muscle strength and muscle mass measurements. We used Timed Up and Go Test (TUG) for evaluation of walking speed, Jamar Hand Dynamometer for muscle strength assessment, and calf circumference for muscle mass measurement. Balances of the patients were evaluated with Berg Balance Scale (BBS) and functional skills were evaluated with the Timed Up and Go Test (TUG). Other clinical parameters (age, body mass index (BMI), 25OHvitD level, menopause age, fall within the last year, fracture history, history of fracture in mother) were questioned.

Detailed Description
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The study was performed on 53 postmenopausal osteoporosis patients who presented to our osteoporosis outpatient clinic. Following written informed consent, patients were evaluated for sarcopenia according to the sarcopenia algorithm proposed by the European Working Group on Sarcopenia in Older People (EWGSOP). Algorithm parameters were walking speed, muscle strength and muscle mass measurements. We used Timed Up and Go Test (TUG) for evaluation of walking speed, Jamar Hand Dynamometer for muscle strength assessment, and calf circumference for muscle mass measurement. Balances of the patients were evaluated with Berg Balance Scale (BBS) and functional skills were evaluated with the Timed Up and Go Test (TUG). Other clinical parameters (age, body mass index (BMI), 25OHvitD level, menopause age, fall within the last year, fracture history, history of fracture in mother) were questioned. SPSS 22.0 program will be used for statistical evaluation and correlation analysis will be done.

Official Title
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Sarcopenia And Balance In Postmenopausal Osteoporosis

Conditions
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Osteoporosis, Postmenopausal, Balance; Distorted, Sarcopenia

Intervention / Treatment
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* Diagnostic Test: Berg Balance Scale
* Diagnostic Test: Timed Up and Go Test
* Diagnostic Test: Jamar hand dynamometer
* Diagnostic Test: Calf circumference


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Having postmenopausal osteoporosis No other disease that can cause balance disorder Volunteer participation in the study Exclusion Criteria: To have a disease that will cause balance disorder, Having understanding problem to prevent communication with the patient, The lack of motor function to the balance device.

Ages Eligible for Study
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Minimum Age: 50 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: postmenopausal osteoporosis<br>Postmenopausal osteoporotic patients evaluated for sarcopenia and balance disorders | Diagnostic Test: Berg Balance Scale<br>* Berg Balance Scale performed for balance disorder<br>Diagnostic Test: Timed Up and Go Test<br>* Timed Up and Go Test for walking speed<br>Diagnostic Test: Jamar hand dynamometer<br>* Jamar hand dynamometer for grip strength which correlates with muscle strength of patient<br>Diagnostic Test: Calf circumference<br>* Calf circumference for muscle mass evaluation. Calf circumference is an anthropometric measurement which correlates with muscle mass.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| sarcopenia in postmenopausal osteoporotic patients | sarcopenia evaluated according to EWGSOP algorithm which includes walking speed, muscle strength and muscle mass measures | 6 months | 
| balance disorder in postmenopausal osteoporotic patients | balance evaluated by Berg Balance Scale ( 0-56 scored scale , bigger score indicates better balance, scores under 41 indicates bigger risk of falling ) | 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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osteoporosis, sarcopenia, balance disorder