The Efficacy of Interferential Current Treatment on Knee Osteoarthritis

Study Overview
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Brief Summary
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The effects of different carrier frequencies of interferential current on pain and function in patients with knee arthrosis will be compared

Detailed Description
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60 patients with knee osteoarhthritis will be enrolled in the study. Subjects will be randomized to 3 groups. All patients will receive interferential currents to both their knees, with different carrier frequencies (2, 4 and 8 kilohertz (kHz) respectively). The effect of different types of carrier frequencies on pain, 10 meter walk test will be analysed.

Official Title
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The Efficacy of Interferential Current Treatment on Knee Osteoarthritis: A Randomized Double Blind Study That Compares the Effects of Different Carrier Frequencies

Conditions
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Knee Osteoarthritis

Intervention / Treatment
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* Device: Interferential current


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age between 50-80 years Knee VAS pain scores ≥ 4 Kellgren-Lawrence radiologic scores 2 and 3 Exclusion Criteria: History of knee surgery Inflammatory arthritis Paralysis of lower extremities Serious cardiovascular disease /presence of cardiac pacemaker Severe osteoarhthritis of lower extremity joints other than the knees History of newly diagnosed cancer (ın the last 6 months) Cognitive impairment

Ages Eligible for Study
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Minimum Age: 50 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: IFC Therapy 2 kHz Arm<br>Subjects in this group will receive interferential current to their knees with a carrier frequency of 2 kHz | Device: Interferential current<br>* An electrotherapy current with different carrier frequencies<br>|
| Experimental: IFC Therapy 4 kHz Arm<br>Subjects in this group will receive interferential current to their knees with a carrier frequency of 4 kHz | Device: Interferential current<br>* An electrotherapy current with different carrier frequencies<br>|
| Experimental: IFC Therapy 8 kHz Arm<br>Subjects in this group will receive interferential current to their knees with a carrier frequency of 8 kHz | Device: Interferential current<br>* An electrotherapy current with different carrier frequencies<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in pain scores according to visual analog scale (VAS) | A visual analog scale value between 0-10. 0 meaning lack of pain and 10 meaning the worst pain the patient has experienced. | At baseline, on the 3rd week visit (last day of interference therapy) and on the 7th week visit | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in functional status levels according to Western Ontario and McMaster Universities Arhtiritis Incex (WOMAC) scale | Womac scale is a questionnaire assessing patients' level of pain and functional status. Scores. Scores range from 0 to 96, 0 representing best and 96 representing worst scores. Pain, stiffness and functional limitation subscores are added up to obtain a total WOMAC score. | At baseline, on the 3rd week visit (last day of interference therapy) and on the 7th week visit | 
| Change in pain status levels according to Western Ontario and McMaster Universities Arhtiritis Incex (WOMAC) scale | Womac scale is a questionnaire assessing patients' level of pain and functional status. Scores. Scores range from 0 to 96, 0 representing best and 96 representing worst scores. Pain, stiffness and functional limitation subscores are added up to obtain a total WOMAC score. | At baseline, on the 3rd week visit (last day of interference therapy) and on the 7th week visit | 
| Change in 10 meter walking test score | This test is a measure that is used to assess walking speed in meters per second over 10 meters. It is used to determine functional mobility. | At baseline, on the 3rd week visit (last day of interference therapy) and on the 7th week visit | 
| Change in the number of paracetamol tablets taken in a week | Number of 500 mg tablets taken over one week will be written by subjects. | At baseline, on the 3rd week visit (last day of interference therapy) and on the 7th week visit | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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interferential current, knee osteoarthritis, pain