Memory Problems Perceptions Among Patients and Accompaniers During Diagnosis Process :

Study Overview
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Brief Summary
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This study aims to prospectively examine the memory problem perceptions of patients with memory complaints [MCs] and their accompaniers during the diagnostic process.

Detailed Description
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Through the french adaptation of the illness perception questionnaire memory, this study aims to prospectively examine the memory problem perceptions of patients with memory complaints [MCs] and their accompaniers during the diagnostic process. The investigators plan to recruit 125 patients with MCs who come for the first time at the Research and Resources Memory Center in Nancy, France. Participants have to express MCs and must be free of dementia diagnosis at the first visit. Participants also need to be accompanied by an accompanier and both have to be fluent in French. This study has been approved by our local Ethics Committee (Committee for the Protection of Persons) and the French Health Security Agency. After giving their informed consent, patients and accompaniers are followed up throughout the diagnostic process with three visits : at their first visit, at one month after the first visit, and at six months after the diagnosis disclosure.

Official Title
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Study of Memory Problems Perceptions With the French Adaptation of the Illness Perception Questionnaire Memory, Among Patients Who Come for the First Time at a Memory Center Until Diagnosis Disclosure Post-visit

Conditions
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Memory Disorders, Alzheimer Disease

Intervention / Treatment
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* Behavioral: Psychological questionnaires


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: For patients with memory complaints: Age over 18 years Have a memory complaints with a QPC score greater than or equal to 3 Be accompanied by a next of kin Folstein MMSE greater than or equal to 15/30 Have given their written consent after receiving clear and intelligible oral and written information Social security coverage For Accompaniers : Age over 18 years Consent to participate at the study with the patient Have given their written consent after receiving clear and intelligible oral and written information Social security coverage Be in contact with the patient at least 8 hours per week. It could be physical contact or telephone contact. Exclusion Criteria: For patients with memory complaints: Sensory deficit interfering with the completion of the questionnaires Level of French insufficient to complete the questionnaires Legally protected person Diagnosis of neurocognitive disorders already established Treatment for Alzheimer Disease Refusal or inability to obtain written informed consent form from the patient Included in another experimental study at inclusion visit For Accompaniers: Sensory deficit interfering with the completion of the questionnaires Level of French insufficient to complete the questionnaires Refusal or inability to obtain written informed consent form from the accompanier

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Patient with memory disorders<br>psychological questionnaires | Behavioral: Psychological questionnaires<br>* Psychological questionnaires about memory problems perceptions, anxiety, depression, quality of life and coping<br>|
| Experimental: Accompanier<br>psychological questionnaires | Behavioral: Psychological questionnaires<br>* Psychological questionnaires about memory problems perceptions, anxiety, depression, quality of life and coping<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Memory problems perceptions of patients and next of kin during diagnosis process | How patients and accompaniers perceive memory problems at the first visit in a Memory Center to 6 months after the diagnosis disclosure, with the Illness Perception Questionnaire Memory | Baseline and 6 months after diagnosis disclosure | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Psychometric properties of the french adaptation of the Ilness Perceptions Questionnaire - Memory (IPQ-M, Hurt et al. 2010) | Psychometric properties of IPQ-M by a traditional approach and by comparison to another french memory complaint questionnaire | Baseline, 1 month later and 6 months after diagnosis disclosure | 
| Impact of the memory problems perceptions on mood and well-being | Correlation between memory problems perceptions at the IPQ-M, levels of anxiety (STAI-Y), depression (MADRS), quality of life (WHOQOL-BREF) and coping strategies. | Baseline and 6 months after diagnosis disclosure | 
| Differences of memory problems perceptions and coping according to level of cognitive disorder at the Mini-Mental State Examination (MMSE) |  | Baseline and 6 months after diagnosis disclosure |