linjc16/ctgov huggingface dataset:
Evaluation of Relationship Between Hypersexuality and Psychostimulant Among Men Who Have Sex With Men

Study Overview
=================
Brief Summary
-----------------
Survey of fifty new psychoactive substances consumers in a context of MTM sexual intercourse. Evaluation using an hetero-assessment questionnaire about the link between hypersexual disorder and the use of synthetic cathinone. Evaluation on psychoactive drug addiction, the induced or pre-existing sexual practices and the medico-psycho-social consequences of those practices.

Official Title
-----------------
Evaluation of Relationship Between Hypersexuality and Psychostimulant Among Men Who Have Sex With Men

Conditions
-----------------
Psychoactive Substances Consumers

Intervention / Treatment
-----------------
* Other: G-STAT questionnaire


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients ≥ 18 years Male homosexual and / or bisexual who come to the CSAPA at the Croix-Rousse Hospital, Lyon France following the use of psychostimulants products in sexual contexts Patients who have received clear information and not opposed to participate in the study Patients affiliated to a social security scheme or similar Patients not undergoing a measure of legal protection Exclusion Criteria: Opposition to participation in the study Patients < 18 years Pregnant women or breastfeeding Deprived of individual liberty

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
Male

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients who use psychostimulants products in sexual contexts<br>Patients who come to the CSAPA at the Croix-Rousse Hospital, Lyon France following the use of psychostimulants products in sexual contexts.These patients come for an addictologique support. The patients will answer to the G-STAT questionnaire. | Other: G-STAT questionnaire<br>* Patients will have a consultation with an addiction specialist physician. During the consultation, the physician ask the patient about these sexual practice and the use of psychostimulants. The patient will answer to the G-STAT questionnaire. This questionnaire allows the physician to perform an initial assessment of the patient's sexual addiction. The entire consultation takes place in the usual practice of consultations for this addiction.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| G-STAT questionnaire | Determine whether there are elements sexual addiction or if its elements are induced by the specific use of psychostimulants. The determination will be made using the interrogation conducted during the CSAPA consultation and G-STAT questionnaire. | Day 0 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
addiction, hypersexuality, psychostimulants
Inhibition Control of Children and Adolescents With ADHD

Study Overview
=================
Brief Summary
-----------------
The objectives of this study are to investigate: the effect of methylphenidate on attention; the relations between methylphenidate and inhibition control and working memory; the relations between inhibition control and verbal attention and working memory; the effect of methylphenidate on the changes of neuropsychological functioning and blood pressure.

Detailed Description
-----------------
Attention deficit hyperactivity disorder (ADHD), characterized by inattention, hyperactivity and impulsivity, is an early onset, highly heritable, clinically heterogeneous, long-term impairing disorder with tremendous impact on individuals, families, and societies. It affects 5-10% of school-aged children worldwide (7.5% in Taiwan). Methylphenidate, a stimulant, is effective in treating these patients. Studies in Taiwan show no effect of methylphenidate on blood pressure. There are evidences show that the change of blood pressure was associated with inhibition of impulsive behaviors. Stop Signal Task(SST) is used to assess the improve of inhibition control after methylphenidate response. By using repeated outcome measurements, we anticipate that this study will evaluate the improvement of neuropsychological performances after medication and determinie the association between medication response and neuropsychological functions and vital signs in a Taiwanese sample.

Official Title
-----------------
Inhibition Control of Children and Adolescents With Attention-Deficit/Hyperactivity Disorder

Conditions
-----------------
Attention Deficit Hyperactivity Disorder

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: The inclusion criteria for the subjects are (1)that subjects have a clinical diagnosis of ADHD defined by the DSM-IV which was made by a full-time board-certificated child psychiatrist; (2)their ages range from 10 to 18 when we conduct the study; (3)their IQ greater than 80; and (4)they are under treatment of methylphenidate. Exclusion Criteria: The subjects will be excluded from the study if they currently meet criteria or have a history of the following condition as defined by DSM-IV: Schizophrenia, Schizoaffective Disorder, Organic Psychosis, or Pervasive Developmental Disorder.

Ages Eligible for Study
-----------------
Minimum Age: 10 Years
Maximum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
Effects of Maternal Body Composition on Offspring Brain Structure and Function

Study Overview
=================
Brief Summary
-----------------
The specific aim of this study is to use MRI methods to evaluate and compare brain structure and function in two groups of full-term neonates at two-weeks of age: those born of obese mothers and those born to normal weight mothers.

Official Title
-----------------
Effects of Maternal Body Composition on Offspring Brain Structure and Function

Conditions
-----------------
Brain Function

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: the participant must be enrolled in the Arkansas Children's Nutrition Center (ACNC) Glowing study and be about 2 weeks of age +/- 3days Exclusion Criteria: none specified

Ages Eligible for Study
-----------------
Minimum Age: 11 Days
Maximum Age: 17 Days

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Normal weight- Non Maternal obesity<br>Full-term neonates at 2 weeks of age born to normal weight mothers | |
| Obese- Obese Mothers<br>Full-term neonates at two weeks of age born of obese mothers | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Brain Structure | We will use high resolution volumetric magnetic resonance imaging (MRI) and Diffusion tensor imaging (DTI) to measure the brain structure of 2 week old infants | Age 2 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Brain Function | We will use high resolution Resting state functional magnetic resonance imaging (rsfMRI) to measure the brain function of 2 week old infants | Age 2 weeks |
Effects of Montelukast on Occult Exercise-Induced Bronchospasm in Athletes

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to determine if treatment of exercise-induced Bronchospasm with montelukast will help college athletes train more effectively and thus become more competitive in a non ergogenic manner.

Detailed Description
-----------------
Exercise-Induced Bronchospasm (EIB) affects between 7-30% of highly trained athletes. The first phase of this study is to screen varsity level college athletes for EIB using Eucapnic hyperventilation (EVH). Those athletes who screen positive, will be enrolled in phase two, a randomized double-blinded placebo controlled double crossover study. At enrollment, athletes will undergo a cardiopulmonary stress test (CPST) and induced sputum sampling and will then be prescribed daily montelukast/placebo for a three week period. Athletes will return after three weeks and repeat the EVH, CPST, and induced sputum. They will then have a one week washout period followed by crossover once again to daily montelukast/placebo for another three weeks. After the second three weeks they will once again return for a final EVH, CPST, and induced sputum. The goal of this study is to demonstrate that effectively blunting the EIB response with montelukast, indices of ventilation,exercise tolerance, and perhaps overall physical fitness improve, allowing athletes to train more effectively, in a nonergogenic manner.

Official Title
-----------------
Effects of Montelukast on Occult Exercise-Induced Bronchospasm in Athletes

Conditions
-----------------
Exercise-Induced Bronchospasm

Intervention / Treatment
-----------------
* Drug: Administration of montelukast or placebo


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: College level varsity athlete age 18yr or older healthy. Able to swallow pills No prior history of asthma Exclusion Criteria: Younger than 18yr smoker Prior history of asthma Unable to swallow pills

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 50 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double


Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: Administration of montelukast or placebo|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Effective blunting of the EIB response by Spirometric measurement |  |  | 
| Improvement in indices of ventilation and cardiopulmonary response measured on CPST |  |  | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Exercise-Induced Bronchospasm, Asthma, Cardiopulmonary Stress Test, Eucapnic Voluntary Hyperventilation, Induced sputum
Liver MRI for Colorectal Cancer Liver Metastasis: Comparative Effectiveness Research for the Choice of Contrast Agents

Study Overview
=================
Brief Summary
-----------------
Magnetic resonance imaging (MRI) has been widely used for problem-solving tool in the evaluation of hepatic lesions, and it has been shown to have better sensitivity than CT for detection of colorectal liver metastases, especially for lesions which are smaller than 1 cm. After introduction of a liver-specific hepatobiliary MR contrast agent, gadoxetic acid, gadoxetic acid-enhanced MRI (Gd-EOB-MRI) has been increasingly used for evaluation of liver lesion including CRLM. However, compared to conventional MRI with extracellular contrast agent (ECA-MRI), Gd-EOB-MRI has different pharmacodynamic characteristics, and is more expensive due to higher cost of gadoxetic acid and needs longer scan time to obtain hepatobiliary phase which is generally acquired 15 to 20 minutes after contrast injection. The purpose of this study was to compare the clinical outcome and diagnostic performance of Gd-EOB-MRI and ECA-MRI for evaluation of focal hepatic lesion in newly diagnosed colorectal cancer.

Conditions
-----------------
Colorectal Cancer

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients with surgically proven colorectal adenocarcinoma patients who underwent abdominopelvic CT and liver MRI for initial staging before any treatment no past or concurrent malignancy other than colorectal adenocarcinoma. Exclusion Criteria: precontrast abdominopelvic CT precontrast liver MRI liver MRI using contrast other than extracellular agent or gadoxetic acid the interval between CT and liver MRI was longer than 4 weeks patients who had suspected multiple hepatic metastases (> 10) on CT distant metastasis other than liver and unavailable reference standard of their hepatic lesions with no pathologic confirmation or follow up imaging.

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 90 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| ECA-MRI group<br>ECA-MRI group (patients who underwent conventional MRI using extracellular contrast agent [ECA]) | |
| Gd-EOB-MRI group<br>Gd-EOB-MRI group (patients who underwent gadoxetic acid-enhanced MRI) | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Disease free survival | From date of curative hepatic surgery until the date of first documented tumor recurrence or date of death from disease-related cause | up to 120 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
colorectal cancer, liver, MRI, contrast, gadoxetic acid
Effectiveness of Sugammadex on Muscle Relaxant Reversal in Preterm Neonates

Study Overview
=================
Brief Summary
-----------------
The primary aim of the work is to compare the efficacy of Sugammadex and neostigmine in reversing rocuronium-induced muscle relaxation to reach complete recovery of neuromuscular block (TOF ratio≥ 0.9) in preterm neonates. The secondary aim is to evaluate the safety of using Sugammadex in preterm neonates and to detect any complications that may occur in this age group.

Official Title
-----------------
Effectiveness of Sugammadex on Muscle Relaxant Reversal in Preterm Neonates

Conditions
-----------------
Sugammadex

Intervention / Treatment
-----------------
* Drug: Sugammadex
* Drug: Neostigmine


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: preterm neonates scheduled for elective inguinal hernia repair Exclusion Criteria: drug hypersensitivity patient is with any diseases affecting the neuromuscular junction Patients with family history of malignant hyperthermia

Ages Eligible for Study
-----------------
Maximum Age: 28 Days

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: (Group N)<br>patients in this group will receive 0.02 mg/kg atropine with neostigmine 0.05 mg/kg IV. to reverse the action of the neuromuscular blocker given. | Drug: Neostigmine<br>* give 0.02 mg/ kg atropine and 0.05 mg/kg neostigmine IV. as muscle reversal drug in premature infants<br>|
| Experimental: (Group S)<br>the patients will receive Sugammadex 2mg/kg IV. As the reversal agent | Drug: Sugammadex<br>* give 2 mg/ kg as muscle reversal drug in premature infants<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Assessment of reversal | Reversal time which is defined as time in seconds from the start of administration of sugammadex or neostigmine to recovery of TOF ratio to 0.9 | immediately after the surgery | 
| Evaluation of recovery | Time for modified Aldrete score to reach 10 | immediately after the surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| number of patients with Complications | any complication during recovery will be noted | immediately after the surgery | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Sugammadex, preterm neonates
Assessment of a Composite Prognostic Score to Predict Severe Forms of Ischemic Colitis

Study Overview
=================
Brief Summary
-----------------
Our objective is to determine a prognostic score including CT, clinical and biological criteria predicting the serious (death / surgery) or non-serious (medical treatment) evolution of ischemic colitis and therefore possibly modify the therapeutic management (propose surgical treatment for a severe form based on prognostic score).

Official Title
-----------------
Assessment of a Composite Prognostic Score to Predict Severe Forms of Ischemic Colitis of Montpellier

Conditions
-----------------
Ischemic Colitis

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion criteria: Age > or = at 18 years old; Performing an abdomino-pelvic scan injected within 6 hours of the onset of symptoms; Ischemic colitis proven by endoscopy or surgical data. Exclusion criteria: CT scan performed without injection and / or after 6 hours following the onset of symptoms; Unproven ischemic colitis.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Complication rate of ischemic colitis | Severe (surgery and/or death) or non severe form of ischemic colitis (medical treatment) : analysis of radiological, biological and clinical data is performed at the time of acute episode of ischemic colitis when the patient is admitted to the hospital or during the stay of the patient previously present in the hospital for another condition | 1 day | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Ischemic colitis, computed tomography
The Burden of Peripheral Artery Occlusion Disease and Associated Factors in Peritoneal Dialysis Patients

Study Overview
=================
Brief Summary
-----------------
The investigators want to evaluate the burden of peripheral artery occlusion disease in Taiwan peritoneal dialysis (PD) patients by using ankle-brachial pressure index (ABI) and toe-brachial pressure index (TBI). Furthermore, the investigators hope to demonstrate the possible casual factors of peripheral artery occlusion disease (PAOD) in PD patients.

Official Title
-----------------
The Burden of Peripheral Artery Occlusion Disease and Associated Factors in Peritoneal Dialysis Patients

Conditions
-----------------
Peripheral Vascular Diseases

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Receive stable peritoneal dialysis patients for more than 3 months Exclusion Criteria: Active infection, malignancy and recent hospitalization

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 90 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Peritoneal Dialysis
Evaluation of Medical Device

Study Overview
=================
Brief Summary
-----------------
A preliminary study was conducted from 01/26/2015 to 10/26/2015 on 605 patients admitted to MIA with an intravenous and/or a urinary catheter. the investigators analyzed: the demographic characteristics of the patient the final diagnosis the patient's severity and the patient outcome after discharge from MIA the justification of the venous and or a urinary catheter the duration of the prescription of the device Evaluation on admission of the need to maintain an intravenous or urinary catheter. Adjusting the prescription in terms of duration or withdrawal of the device in order to limit their complications (lymphangitis, superficial thrombophlebitis, bacteremia related to health care, urinary tract infection). Hypothesis: Limit the length of stay and reduce the cost of hospitalization.

Official Title
-----------------
Evaluation of Peripheral Intravenous Catheter and Urinary Catheters Present on Admission to the Maladies Infectieuses aiguës Department.

Conditions
-----------------
Acute Infectious Diseases

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patient with an intravenous catheter and/or a urinary catheter. Patient is more than 18 years old. Patient who accepts to have his medical records reviewed for research. Patient with health insurance Exclusion Criteria: Refusal of participation in the study

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| number of patients with intravenous catheter |  | 3 YEARS | 
| number of patients with urinary catheter |  | 3 YEARS |