Application of High Resolution Diffusion-weighted MR Imaging Pulse Sequence in Head and Neck, and Prostate Cancers

Study Overview
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Brief Summary
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Magnetic resonance imaging (MRI) is a diagnostic study that makes pictures of organs of the body using magnetic field and radio frequency pulses that can not be felt. The purpose of this study is to determine if a new MR imaging method can help tumor evaluation in head and neck cancer or prostate cancer. The extra images will be obtained using Diffusion-weighted Magnetic Resonance Imaging which provides image contrast through detection of small restrictions in the movement of water molecules. This study may help us provide additional information about the tumor along with the picture of the organ.

Official Title
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Application of High Resolution Diffusion-weighted MR Imaging Pulse Sequence in Head and Neck, and Prostate Cancers

Conditions
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Head and Neck Cancer, Prostate Cancer

Intervention / Treatment
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* Other: MRI scanner with sequence


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adults aged 18 and over. Men and women without regard to ethnic background. Patients/Subjects able to give informed consent Patients/Subjects whose weight does not exceed 275 lbs. Patient with a known or suspected head and neck cancer or prostate cancer scheduled for an MRI scan as part of their routine care --OR-- Volunteer with no history of the disease in that category. Exclusion Criteria: Patients who are unwilling or unable to undergo MRI including patients with contra-indications to MRI such as the presence of cardiac pacemakers or non-compatible intracranial vascular clips.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Pts having an MRI<br>This is a technology assessment protocol. The study is designed to assess the utility of the technology using a limited number of participants. | Other: MRI scanner with sequence<br>* The intervention for the patients is the additional 10 minutes in the MRI scanner with sequence. The intervention for the volunteers is the scan, which will take a total of 30 minutes. The volunteers will have two more additional studies at 1-2 week intervals. Both the patients and volunteers will also need to fill out a questionnaire.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| feasibility of high resolution diffusion-weighted imaging | using a new DWI pulse sequence from the manufacturer (General Electric Medical Systems (Milwaukee, WI)) for the assessment of head and neck cancer cancer and prostate cancer. | 2 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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MRI, MR imaging Pulse Sequence, High Resolution Diffusion-weighted, Questionnaire, 12-033