Cogmed for Working Memory After TBI

Study Overview
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Brief Summary
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This study will examine a cognitive rehabilitation protocol targeted at working memory deficits for adults and children with Traumatic Brain Injury (TBI). In this randomized clinical trial, the efficacy of Cogmed, a cognitive rehabilitation protocol designed to improve working memory, will be examined in children with TBI. Neuropsychological and daily life functioning will be measured. Participants will be children (N=20) and adults (N=20) with a documented history of TBI. Participants will be randomized to a treatment group or a wait list control group. The Experimental Group will receive the Cogmed working memory training program 30-40 minutes per day, 5 days a week for 5 weeks for a total training time of approximately 15 hours. The Control Group will be a wait list control group that will cross over into treatment after the follow-up assessment. All subjects will undergo repeat assessments following completion of the working memory training protocol after the 7th week and again at 13 weeks to document changes in working memory performance.

Official Title
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Applying Cogmed to Improve Working Memory Abilities After Traumatic Brain Injury

Conditions
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Traumatic Brain Injury

Intervention / Treatment
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* Behavioral: Cogmed


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: History of Traumatic Brain Injury Exclusion Criteria: Diagnosis of other neurological conditions

Ages Eligible for Study
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Minimum Age: 9 Years
Maximum Age: 59 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Cogmed<br>Cogmed is a cognitive rehabilitation protocol designed to improve working memory. The Cogmed sessions are on a computer at home for 30-40 min per day, 5 days per week for 5 weeks. | Behavioral: Cogmed<br> <br> |
| No Intervention: Wait list<br> | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in scores on standardized tests of working memory | Measured via standardized neuropsychological tests (i.e. paper and pencil testing) | Three points in time: Baseline assessment, Week 7 and Week 13 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in scores on self report measures of emotional functioning, assessed via questionnaire |  | Three points in time: Baseline assessment, Week 7 and Week 13 | 
| Change in scores on self report measures of memory functioning, assessed via questionniare |  | Three points in time: Baseline assessment, Week 7 and Week 13 | 
| Change in scores on self report measures of quality of life, assessed via questionnaire |  | Three points in time: Baseline assessment, Week 7 and Week 13 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Working Memory