Safety of Preoperative Carbohydrate Loading in Diabetic Patients

Study Overview
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Brief Summary
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The purpose of this study is to investigate the safety of preoperative carbohydrate loading in diabetic patients undergoing general anesthesia

Official Title
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Safety of Preoperative Carbohydrate Loading in Diabetic Patients Undergoing General Anesthesia

Conditions
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Carbohydrate Intolerance, Diabetes Mellitus Type 2

Intervention / Treatment
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* Dietary Supplement: noNPO


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Elective surgery Type 2 diabetes mellitus on oral hypoglycemic agents American Society of Anesthesiologists physical status 2 or 3 Ages 18 or more Approve to participate Exclusion Criteria: Ambulatory surgery BMI >35 History of gastric or esophagus surgery History of GERD, dyspepesia or Anticipated difficult intubation (previous III or more Cormack and Lehane's grade, Mallamgrade, Mallampati scpati scoreore III or moreIII or more, propro/retro/retrognathism, gnathism, thyromental distance<6.5cm, thyromental distance<6.5cm, limited mouth openinglimited mouth opening)

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patient who received carbohydrate loading<br>Patients with diabetes mellitus type 2 who are planned to receive a carbohydrate beverage (400 ml (12.8% carbohydrates, 50 kcal/100 ml; Nucare NONPO Ⓡ , Daesang Wellife, Korea) before the operation and up to 2 hours before the induction of anesthesia outside this clinical study setting | Dietary Supplement: noNPO<br>* Patients with diabetes mellitus type 2 who are planned to receive a carbohydrate beverage (400 ml (12.8% carbohydrates, 50 kcal/100 ml; Nucare NONPO Ⓡ , Daesang Wellife, Korea) before the operation and up to 2 hours before the induction of anesthesia outside this clinical study setting will be asked to be enrolled into the study. Before induction of general anesthesia, all patients were evaluated the gastric volume under ultrasonography.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of gastric ultrasonography score as low risk (grade 0 or 1) | Ultrasound assessment of gastric volume by gastroscopic examination. | 30 minutes after intubation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Gastric volume |  | 30 minutes after intubation | 
| Blood sugar test |  | 30 minutes after intubation and 30 minutes after extubation | 
| The incidence of insulin bolus injection |  | during operation | 
| The incidence of insulin bolus injection |  | up to 30 minutes after extubation | 
| Satisfaction scale of patients |  | up to 30 minutes after extubation | 
| The incidence of nausea and vomiting |  | up to 30 minutes after extubation | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Carbohydrate Intolerance, Diabetes Mellitus, Diabetes Mellitus, Type 2, Carbohydrate loading