linjc16/ctgov huggingface dataset:
Analysis of Balance in the Aging Process

Study Overview
=================
Brief Summary
-----------------
Introduction: While growing older, it is possible to notice a decrease in the functional and physiological reserves in the organism which impairs the the abilities in the elderly in doing some tasks. A simple balance becomes a challenge. Objective: To evaluate the functional balance in the aging process. Methods: The group was formed by 48 people from 10 to 85 years old. The evaluation instruments are the Berg Balance Scale (BBS), the Performance Oriented Mobility Assessment (POMA), the Unipodal Support Test, the Functional Reach Test and the Romberg's Test.

Detailed Description
-----------------
48 individuals of both sexes and aged between 10 and 85 years were chosen. These individuals were divided according to age, into four groups (each group containing 12 individuals, 6 men and 6 women): Group I (G1): 10 - 18, Group II (G2): 20 - 35; Group III (G3): 45 - 60, Group IV (G4): 65 - 85. The instruments used for assessment of the balance were: (1) Berg Scale - consists of 14 items with common activities of daily life, with progressive degree of difficulty (2) Assessment of Gait and Balance for Performance Oriented (POMA), consists of a protocol that evaluates the static and dynamic balance, with operations similar to the activities of daily living, (3) Test Support Unipodal; (4) adapted Functional Reach Test, which assesses the stability in the standing position, (5) Test and Romberg Romberg's test Romberg-Barré or sensitized conducted in stable and unstable soil, and all positions were first with open eyes and then with closed eyes. The duration of each exposure was 30 seconds, with different positioning of the feet.

Official Title
-----------------
Analysis of Balance in the Aging Process

Conditions
-----------------
Aging

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Absence of the basic pathology that interferes directly in the balance Exclusion Criteria: Neurological changes Cognitive impairment Orthopedic injury Use of orthoses for lower limb Obesity Exercise frequently (more than twice a week) The bearer of any commitment to stay in their standing position

Ages Eligible for Study
-----------------
Minimum Age: 10 Years
Maximum Age: 85 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Group I<br>(G1): 10 - 18 years old | |
| Group II<br>(G2): 20 - 35 years old | |
| Group III<br>(G3): 45 - 60 years old | |
| Group IV<br>(G4): 65 - 85 years old | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Aging, Postural Balance
Hysteroscopic Evaluation of Cesarean Scar Defect

Study Overview
=================
Brief Summary
-----------------
The aim of this study is to identify hysteroscopic findings of cesarean scar defect in women underwent at least one prior cesarean section and its relation to any of the different un explained gynecological presentations.

Official Title
-----------------
Hysteroscopic Evaluation of Cesarean Scar Defect Features & Its Correlation With Women Complaints

Conditions
-----------------
Cesarean Scar Defect

Intervention / Treatment
-----------------
* Procedure: Diagnostic hysteroscopic examination


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age between 18 and 35 years. Had at least one prior cesarean section Exclusion Criteria: History of uterine surgery that could change the cavity anatomy. Uterine Abnormalities as submucous fibroid, endometrial or endocervical Polyps. Recent intra-uterine contraceptive device (IUCD) in place. Known history of endometriosis

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 35 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: Diagnostic hysteroscopic examination|The hysteroscopic criteria of the cesarean scar defect will be observed with comment on different niche features|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| cesarean section scar defect shapes | different shapes of CS defect and its relation to post menstrual spotting | at least six months after CS |
Outcome of Small Pupil Phacotrabeculectomy in Persons With Glaucoma and Cataract

Study Overview
=================
Brief Summary
-----------------
Small pupils are not uncommon in situations requiring surgical intervention for glaucoma and cataract. Inadequate binocular view during combined trabeculaectomy and glaucoma surgery needs to be overcome by additional iris manupulations to dilate the pupils which increase the liklihood of inflammation, inraocular pressure rise after surgery and enhnced liklihood of failure of glaucoma surgery. The proposed trial is an observational study to analyse post operative outcome of eyes undrgoing trabeculectomy and phacoemulsification with intraocular lens implantation with small pupils in persons with glaucoma coexisting with cataract.

Detailed Description
-----------------
Small pupils are not uncommon in situations requiring surgical intervention for glaucoma and cataract. Inadequate binocular view during combined trabeculaectomy and glaucoma surgery needs to be overcome by additional iris manupulations to dilate the pupils which increase the liklihood of inflammation, inraocular pressure rise after surgery and enhnced liklihood of failure of glaucoma surgery. The proposed trial is an observational study to analyse post operative outcome of eyes undrgoing trabeculectomy and phacoemulsification with intraocular lens implantation with small pupils in persons with glaucoma coexisting with cataract

Conditions
-----------------
Glaucoma, Cataract

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Individuals with visually significant cataracts and medically uncontrolled primary open angle, angle clsoure, exfolaitive glaucoma Exclusion Criteria: Complicated catracts and secondary glaucoma

Ages Eligible for Study
-----------------
Minimum Age: 40 Years
Maximum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
glaucoma, catarat, small pupils
Abortions at Strasbourg University Hospitals

Study Overview
=================
Brief Summary
-----------------
The number of abortions in France and Strasbourg has been stable for several years. In 2017, 1847 were performed in the Gynecology-Obstetrics Department for 6146 deliveries (23% of all pregnancies). It therefore seems important to evaluate the professional practices, but also the experiences of the patients.

Official Title
-----------------
A Survey of Best Practices of Abortions at Strasbourg University Hospitals

Conditions
-----------------
First-trimester Pregnancy

Intervention / Treatment
-----------------
* Procedure: Evaluation of the procedure of abortion


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion criteria: Patient in the first trimester of pregnancy wishing an abortion Age: greater than or equal to 18 years. Patient affiliated to a social security system Exclusion criteria: Patient after the first trimester pregnancy Patient benefiting from a legal protection measure Bad understanding of French.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Request for abortion<br>Patient in first trimester of pregnancy in request for abortion | Procedure: Evaluation of the procedure of abortion<br>* Observational study using questionnaires<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluate the investigator's professional practices regarding abortion, particularly in relation to the recommendations for clinical practice of the National College of French Obstetricians Gynecologists (CNGOF) published in 2016. | The patients will complete a questionnaire | 6 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluation of the sociological, economic and psychological factors motivating the request for abortion | The patients will complete a questionnaire | 6 weeks | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
First-trimester pregnancy, Abortions
Nectin-4 Specific LMW PET Probe Imaging in Urothelial Carcinoma

Study Overview
=================
Brief Summary
-----------------
To evaluate the ability of [68Ga]N188 to detect nectin-4 overexpression in patients with urothelial carcinoma, especially in patients with recurrent or advanced bladder cancer.

Official Title
-----------------
Nectin-4 Specific LMW PET Probe Imaging in Urothelial Carcinoma

Conditions
-----------------
Urothelial Carcinoma

Intervention / Treatment
-----------------
* Drug: 18F-FDG


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 18-75 years old, male or female; Heart function is normal; Normal heart function; Estimated survival ≥12 weeks; Good follow-up compliance; presence of at least one measurable target lesion according to RECIST1.1 criteria; Women of childbearing age (15-49 years) must have a negative pregnancy test within 7 days before starting the test; Fertile men and women must agree to use effective contraception to prevent pregnancy during the study period and for 3 months after the test; Patients recommended by clinicians to undergo PET/CT examination for tumor diagnostic staging; The subject patients could fully understand and voluntarily participate in the experiment, and signed the informed consent. Exclusion Criteria: Serious abnormality of liver, kidney and blood; Pregnant patients; Pregnant and lactation women; 3) unable to lie flat for half an hour; 4) Refuse to join the clinical investigator; 5) Suffering from claustrophobia or other mental diseases; 6) Other conditions that researchers deem unsuitable for participating in the experiment.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 68Ga-N188<br>Imaging cohort All study participants will be allocated to this arm (single-arm study). Study participants will undergo 68Ga-N188 PET/CT scan. | Drug: 18F-FDG<br>* All study participants will undergo one 18F-FDG PET/CT scan.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Standardized uptake value（SUV） | SUV is a semi-quantitative analysis index to describe the radioactive uptake of lesions, which has certain reference value for differentiating benign and malignant lesions。 The uptake of the tracer （68Ga-N188） in urothelial carcinoma tumor lesions by measuring SUV on PET/CT. | 2 years |
TROMS (Trainee Reported Outcome Measurement): the New Era of Surgical Evaluation

Study Overview
=================
Brief Summary
-----------------
TROMS (trainee reported outcome assessment): assessment of surgical training of residents in general surgery

Official Title
-----------------
TROMS (Trainee Reported Outcome Measurement): the New Era of Surgical Evaluation

Conditions
-----------------
Surgical Procedure, Unspecified

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion criteria: All surgical residents in the department of general and digestive surgery Exclusion criteria: Not applicable
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Assessment of surgical skills achieved by residents | Surgical performance will be evaluated in a random assigned operation by mentors using an specific OPRS (Operative Performance Rating System) | 5 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Trainee reported outcomes measurements | Using a specific scale, we aim to measure the satisfaction perceived by our surgical residents concerning their training | 5 years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
TROMS, PROMS, surgical assessment, learning curve, OSATS, MIR
Buprenorphine Detoxification - BBDVI - 19

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to examine the long-term efficacy of alternate-day dosing schedules in promoting treatment compliance in the absence of confounding behavioral contingencies.

Official Title
-----------------
Buprenorphine Detoxification - BBDVI

Conditions
-----------------
Opioid-Related Disorders

Intervention / Treatment
-----------------
* Drug: Buprenorphine


Participation Criteria
=================
Eligibility Criteria
-----------------
Please contact site for information.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment


Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: Buprenorphine|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Drug use |  |  | 
| Retention |  |  | 
| Weeks abstinent |  |  | 
| Weeks continuous abstinence |  |  | 
| Overall treatment outcome |  |  | 
| Opioid dependence and psychiatric status |  |  |
Evaluation of Programs of Reeducation for Urinary Incontinence in Woman

Study Overview
=================
Brief Summary
-----------------
The objective of this study is to compare two methods of pelvic floor muscle training: reference method versus CMP ® method ( (Connaissance et Maîtrise de Périnée : Knowledge and Control of Perineum)

Conditions
-----------------
Urinary Incontinence

Intervention / Treatment
-----------------
* Other: Reference method
* Other: CMP ® method


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients more than 18 years old and less than 75 years Patients presenting an urinary incontinence of effort or mixed symptomatic associated with a pelvic statics disorder Patients with a perineale reeducation prescription Patients affiliated to a national insurance scheme or benefiting from such a program Patients having given her written consent form Exclusion Criteria: Nulliparous woman Patients already operated for their incontinence Patients with a prolapse of higher level at the stage II of the classification POP-Q (Pelvic Organ Prolapse Quantification) Pregnant women Patients presenting an associated anal incontinence, Patients presenting a cancellation (section of marrow, syringomyelia for example) or an inversion of perineum control Patients having given birth less than 6 months before the care Patients having benefited from a pelvi-périnéale reeducation in the previous 12 months, Patients presenting psychiatric disease Patients presenting a vaginismus, Patients presenting a contraindication to the practice of the electrostimulation.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Group A<br>Reference method | Other: Reference method<br>* Electrostimulation associated to perineal training<br>|
| Experimental: Group B<br>CMP ® method (Knowledge and Control of Perineum) | Other: CMP ® method<br>* Method based on Knowledge and Control of Perineum<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| USP (Urinary Symptoms Profile) score | Urinary Symptoms Profile score | 38 weeks |
Prevalence of Anterior Open Bite in a Group of Egyptian Children Aged Eight Years and Above

Study Overview
=================
Brief Summary
-----------------
This study aims to determine the prevalence of anterior open bite and its etiological factors in a group of Egyptian children aged 8 years and above. patients who met the eligibility criteria will be given a questionnaire to fill followed by obtaining casts stabilized into occlusion to obtain the vertical and horizontal relationships.

Official Title
-----------------
Prevalence of Anterior Open Bite in a Group of Egyptian Children Aged Eight Years and Above: A Cross Sectional Study

Conditions
-----------------
Anterior Open Bite

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Medically free children aged 8 years and above, both genders and cooperative parents and children Exclusion Criteria: Presence of orthodontic appliance and parents refuse to participate

Ages Eligible for Study
-----------------
Minimum Age: 8 Years
Maximum Age: 14 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Anterior Open bite | Overbite and Overjet measurement by obtaining a cast to determine anterior open bite in millimeters | 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Its different etiological factors | Asking patient/ caregiver through a (Questionnaire) | 1 year |
Effects of Buprenorphine/Naloxone in Treating Opioid Dependent Individuals Who Are Maintained on Methadone

Study Overview
=================
Brief Summary
-----------------
Buprenorphine is a drug that may be helpful in treating opioid dependent individuals who were previously maintained on methadone. The purpose of this study is to determine the effects of different doses of buprenorphine/naloxone in treating opioid dependent individuals who were previously maintained on methadone.

Detailed Description
-----------------
Buprenorphine is a mixed agonist-antagonist opioid that is being developed as a treatment for opioid dependence. Because buprenorphine is a partial mu agonist opioid, under certain conditions it is possible for buprenorphine to precipitate opioid withdrawal in opioid dependent individuals. A person with a high level of physical dependence could experience buprenorphine-related precipitated withdrawal. The purpose of this study is to test the acute effects of different doses of buprenorphine/naloxone in opioid dependent individuals maintained on methadone. The study is designed to provide dosing schedules similar to those that might be initially used in a physician's office.

Official Title
-----------------
Transitioning Patients From Methadone to Buprenorphine/Naloxone for Treating Opioid Dependence

Conditions
-----------------
Opioid-Related Disorders

Intervention / Treatment
-----------------
* Drug: Buprenorphine


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Meets criteria for opioid dependence Exclusion Criteria: Significant medical or psychiatric illness

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 55 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: Buprenorphine|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Physiological effects |  |  | 
| Analog rating scale for drug effects |  |  | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
opioid dependence