Transcutaneous Pulsed Radiofrequency in Migraine

Study Overview
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Brief Summary
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The aim of the investigator is to compare the efficacy of greater occipital nerve block and transcutaneous pulsed radiofrequency treatment in migraine.

Detailed Description
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Migraine is the second most common primary headache. Greater occipital nerve (GON) block is an effective method in the treatment of migraine. Transcutaneous pulsed radiofrequency (RF) therapy is used in the treatment of pain. However, its use in headaches is not widespread yet. Investigator aimed to compare the efficacy of transcutaneous pulsed radiofrequency therapy applied through the GON trace and GON block therapy. A 60-patient study was designed. GON block was planned for 30 patients and transcutaneous pulsed RF was planned for 30 patients. The block will be applied once at the level of C2 vertebra with ultrasound.Transcutaneous pulsed RF will be applied twice, once a week, for 8 minutes.All patients will have pre-treatment migraine disability assessment score (MIDAS) scores filled. A headache diary will be provided to all patients. Frequency and severity of pain will be followed for 1 month. Pain intensity will be evaluated on the visual analog scale (VAS). Investigator aimed to evaluate the efficacy of transcutaneous pulsed RF therapy, which is a noninvasive method, in migraine.

Official Title
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Comparison of Transcutaneous Pulsed Radiofrequency Therapy and Greater Occipital Nerve Block Efficiency in Migraine Headache

Conditions
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Migraine Disorders

Intervention / Treatment
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* Drug: Bupivacaine Hydrochloride
* Other: Transcutaneous pulsed radiofrequency qurrent


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Chronic Migraine Exclusion Criteria: Other headaches will not accompany (tension-type headache, cluster...) Pregnancy

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: GON block group<br>30 patients who underwent greater occipital nerve block | Drug: Bupivacaine Hydrochloride<br>* 2.5 cc bupivacain injection will be administered by approaching the greater occipital nerve under ultrasound guidance.<br>|
| Active Comparator: Transcutaneous pulsed RF group<br>30 patients who underwent greater occipital nerve pulsed radiofrequency | Other: Transcutaneous pulsed radiofrequency qurrent<br>* Pulsed radiofrequency current will be applied through transcutaneous pads adhered over the greater occipital nerve trace on the nape.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The Migraine Disability Assessment Test | The MIDAS questionnaire is an important part of a package of educational, investigative, and therapeutic measures, and could play a major role in improving the care of patients with migraine and other types of headache. | Baseline | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual analog scale (VAS) | It is a scale that measures the severity of pain. Scored between ''0: no pain'' and ''10: worst pain'' . | Baseline, Week 4 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Transcutaneous pulsed radiofrequency, pulsed radiofrequency treatment, headache, GON block