Normal Polysomnography Values in Healthy Children and Adolescents in China

Study Overview
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Brief Summary
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The study is designed to investigate normal polysomnographic respiratory values of Chinese healthy children and adolescents. By collecting the polysomnography (PSG) data and parameters of respiratory and sleep architecture，we hope to characterize normal polysomnography values in Chinese children and adolescents and to establish respiratory reference values for pediatric polysomnography which based on Chinese children's data.

Detailed Description
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We plan to recruit 200 healthy, normal children and adolescents in this study, age ranging from 3 to 15 years. All of them will be invited to undergo an overnight polysomnography for at least 7h in Beijing Children's Sleep Center, meanwhile the parameters about sleep including EEG, electromyography, electrooculography, ECG, pulse oximetry arterial oxygen saturation (SpO2), chest wall and abdomen motion, oral and nasal airflow, and end-tidal PCO2 (PETCO2) will be recorded. Based on the data we hope to give recommendation of normal PSG parameters of Chinese kids, and on this basis,to develop the diagnosis creteria for obstructive sleep apnea syndrome which will be more suitable for Chinese children conditions.

Official Title
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Research to Characterize Normal Polysomnography Values in Healthy Children and Adolescents in China

Conditions
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Sleep Apnea

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 1.3 to 14-year-old children 2.from the community of China 3.healty children Exclusion Criteria: children with nocturnal snoring, continuous mouth breathing, difficulty breathing and apnea when sleep. children with craniofacial abnormalities, such as Down's syndrome, Crouzon syndrome, achondroplasia, mandibular hypoplasia and facial mandibularetc hypoplasia. children with history of upper respiratory tract infection nearly two weeks. children with adenoids, tonsils, throat, glottis, trachea, lungs and history of thoracic surgery. children with nose-sinusitis, allergic rhinitis, asthma, acut or purulent tonsillitis acute phase. children with any medical or surgicaldiseases. children who have to use use sedation to maintain sleep. parents or child not understand the study or do not agree to take part in.

Ages Eligible for Study
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Minimum Age: 3 Years
Maximum Age: 14 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Preschool group<br>3-6 years old | |
| school age group<br>7-12 years old | |
| Adolescence group<br>13-15 years old | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| obstructive apneas per hour of sleep |  | 7 hours of sleep | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| minimum oxygen desaturation of sleep |  | 7 hours of sleep | 
| central apneas per hour of sleep |  | 7 hours of sleep | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Children, Polysomnography, sleep, obstructive sleep apnea;, Chinese