Super Chinese Nephrotic Syndrome Registration System (SUCCESS)

Study Overview
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Brief Summary
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The investigators are registering all nephrotic syndrome (NS) patients regardless of the primary causes and developing a NS database in China. Patients will be followed-up and both baseline and follow-up information will be recorded in the registration system. The treatment response, longitudinal changes of renal function, renal survival, patient survival, infection events and acute kidney injury etc, will be analyzed using the NS database.

Detailed Description
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The investigators are registering all NS patients regardless of the primary causes in China. Patients' demographic characteristics (including age, gender, height, weight, BMI, smoking, drinking, and education), clinical characteristics (including systolic blood pressure, diastolic blood pressure, primary cause of NS, and lab measurements of serum, urine), pathological characteristics, treatment and treatment response, complications and outcomes. Patients will be followed up, the demographic, clinical characteristics, treatment, lab tests of blood and urine and complications of patients will be collected and recorded at each visit. The investigators also record the outcome at each visit, such as treatment response, longitudinal changes of renal function, hospitalization, occurrence of infection or cardiovascular events etc. The outcomes will be analyzed using the NS database.

Official Title
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Super Chinese Nephrotic Syndrome Registration System (SUCCESS)

Conditions
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Nephrotic Syndrome

Intervention / Treatment
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* Other: No intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Nephrotic syndrome patients regardless of the primary causes Exclusion Criteria: No

Ages Eligible for Study
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Minimum Age: 14 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Nephrotic syndrome patients<br>Patients diagnosis as nephrotic syndrome (NS) | Other: No intervention<br>* Registration of all NS patients in the First Affiliated Hospital of Sun Yat-sen University and other hospitals which have signed the contract in China.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The patient survival in NS patients |  | 10 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Renal survival in NS patients | Renal survival including end stage renal disease, dialysis, renal transplantation | 10 years | 
| Longitudinal changes of renal function of NS patients |  | 10 years | 
| Treatment response of NS patients |  | 10 years | 
| Infection rate of NS patients |  | 10 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Nephrotic syndrome, Treatment response, Renal function