Functional Outcomes of Stay Strong Stay Healthy Program

Study Overview
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Brief Summary
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Strength training can increase muscle mass and strength while improving bone density and reducing risk for osteoporosis and related fractures. Strength training can also lead to reduced risk for diabetes, heart disease, arthritis, depression, and obesity; and improves self-confidence, sleep and vitality. Research demonstrates that strength training is extremely effective in helping aging adults with chronic conditions prevent further onset of disease and, in many instances, actually reverse the disease process. In Stay Strong, Stay Healthy Program elderly subjects perform resistance exercise training (RET) twice every week. Past literature suggests that resistance training improved muscle activity, muscle strength, muscle mass, and bone mineral density and total body composition, and adiponectin, insulin sensitivity, fasting blood-glucose (BG), HbA1c1 (long-term marker of BG), blood pressure (BP), blood triglycerides (TGs) and low density lipoproteins (LDL) in healthy and diabetic subjects. The purpose of this study is to measure the changes in the above discussed variables after 8-weeks of resistance exercises.

Detailed Description
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Participants will perform resistance exercise for 8 weeks and measurements (anthropometric, electromyography, pulse wave velocity, strength test, dual x-ray absorptiometry, blood enzymes/hormones, and sleep, diet, memory surveys) will be performed pre- and post-exercise program.

Official Title
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Functional Outcomes of Stay Strong, Stay Healthy Program

Conditions
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Quality of Life, Aging, Memory Loss, Cardiovascular Diseases

Intervention / Treatment
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* Other: Resistance Exercise


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 60 or above Enrollment in Stay Strong Stay Healthy Program Strength training < 2 hours/week for past 3 months Exclusion Criteria: Not enrolled in Stay Strong Stay Healthy Program Strength training > 2 hours/week for past 3 months Donated more than 463 ml of blood in past 8 weeks Physician discouraged to participate

Ages Eligible for Study
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Minimum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Older adults<br>Participants 60 and above aged (both females and males) will perform one hour of resistance exercise twice weekly for 8 weeks. | Other: Resistance Exercise<br>* Participants 60 and above aged (both females and males) will perform one hour of resistance exercise twice weekly for 8 weeks.<br>* Other names: Strength training;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Muscle electrical activity | Measurement of muscle electrical activity is made using electromyography technique at baseline and after 8 weeks of resistance exercise. | Change in muscle electrical activity in 8 weeks in response to resistance exercise program | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Exert muscle power/strength | Measurement of muscle power/strength is made using hand dynamometer at baseline and after 8 weeks of resistance exercise. | Change in muscle power/strength in 8 weeks in response to resistance exercise program | 
| Muscle mass loss | Changes in the muscle mass is made using dual x-ray absorptiometry technique at baseline and after 8 weeks of resistance exercise. | Change in muscle mass in 8 weeks in response to resistance exercise program | 
| Ability to think or remember | Changes in ability to think or remember is measured by using standard survey (Self Administered Gerocognitive Exam Form -1) at baseline and after 8 weeks of resistance exercise. | Changes in thinking and cognitive abilities in 8 weeks in response to resistance exercise program | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Elderly, Older, Adults, Resistant Exercise, Strength Training, Cognitive function