AnovaOS Network Powered Patient Registry

Study Overview
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Brief Summary
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The objective of this study is the development, implementation and management of a registry of patient data that captures clinically meaningful, real-world, data on the diagnosis, nature, course of infection, treatment(s) and outcomes in patients with complex disease globally.

Detailed Description
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The AnovaOS™ Network Powered Patient Registry may be used to inform the development and conduct of clinical trials and observational studies designed to better understand, prevent, diagnose, treat, ameliorate or cure disease. The AnovaOS™ Network Powered Patient Registry may additionally be used to expedite identification and recruitment of participants for clinical trials of promising therapeutics and observational studies.

Official Title
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AnovaOS Network Powered Patient Registry

Conditions
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Congenital Malformations, Deformations and Chromosomal Abnormalities (Q00-Q99), Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified, Injury, Poisoning and Certain Other Consequences of External Causes, Endocrine, Nutritional and Metabolic Diseases (E00-E89), External Causes of Morbidity and Mortality, Factors Influencing Health Status and Contact With Health Services, Infectious Disease, Neoplasms, Diseases of the Blood and Blood-Forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89), Mental and Behavioural Disorders, Diseases of the Nervous System, Diseases of the Eye and Adnexa, Diseases of the Ear and Mastoid Process, Diseases of the Circulatory System, Diseases of the Respiratory System, Diseases of the Digestive System, Diseases of the Skin and Subcutaneous Tissue, Diseases of the Musculoskeletal System and Connective Tissue, Diseases of the Genitourinary System, Pregnancy, Childbirth and the Puerperium, Certain Conditions Originating in the Perinatal Period

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 18 years old or older; Confirmed positive diagnosis of disease, condition or disorder. This will be self-reported or reported by the patient's provider, advocacy group or other patient representative; Laboratory or other independent means of confirmation is not required but may be confirmed in clinical trials; Able to understand and willing to sign the informed consent document; or whose legal representative has given consent to participate in the research per state and Federal requirements; Willing and able to complete the registry questions or have the instrument(s) completed by an informed proxy; Anticipated additional follow up with the registry once per year. Exclusion Criteria: Subjects who do not meet the inclusion criteria for the study; Subjects who are unable to understand the protocol or unable to provide legally effective informed consent

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Assess Natural history | Assessing natural history, including estimating the magnitude of a problem; determining the underlying incidence or prevalence rate of a condition; examining trends of disease over time; assessing service delivery and identifying groups at high risk; and describing and estimating survival; | 5 years | 
| Assess Clinical, Cost and/or Comparative Effectiveness | Determining clinical effectiveness, cost effectiveness, or comparative effectiveness of a test or a treatment; | 5 years | 
| Assess Safety | Measuring and monitoring safety and harm associated with the use of specific products and treatments, including conducting comparative evaluation of safety and effectiveness; | 5 years | 
| Measuring and/or Improving Quality of Care | Measuring or improving quality of care, including conducting programs to measure and/or improve the practice of medicine and/or public health. | 5 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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infectious disease, cancer/oncology, neurology, immunology, cardiology