Comparison to Early Detect of the Sepsis

Study Overview
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Brief Summary
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The aim of the study was to identify co-variates associated with 30-day mortality in septic patients admitted to the emergency department in order to improve morbidity & mortality as a sequence of sepsis in Assiut & Suez Canal Universities by comparing both scores by utilizing parameters that are readily available .

Detailed Description
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There are a relatively large number of conditions where urgent intervention is required in order to secure the best outcome for the patient. Examples include sepsis, myocardial infarction (MI). Clinical diagnosis of some of these conditions is not always straightforward, but a common theme is that many present with deranged physiology and vital signs. Implementation of an early warning score on arrival at hospital has helped to identify seriously ill patients . There is a high mortality rate associated with severe infection at all ages Sepsis occurs when life-threatening organ dysfunction is associated with infection. What is a national early warning score (NEWS)? The following six simple physiological parameters are included in the scoring system: respiratory rate, oxygen saturation, temperature; the normal human body temperature range is typically stated as 36.5-37 °C( ), systolic blood pressure, pulse rate & level of consciousness. What is a sepsis patient evaluation in the emergency department (SPEED)? The following simple clinical, physiological and laboratory parameters are included in the scoring system : hypotension (systolic pressure <90 mmHg) hypothermia (body temperature <36.0°C) , hypoxemia (pulse oximetry <90%), low hematocrit (hematocrit <0.38), Acidosis (blood PH < 7.35), elevated blood lactate >2.4 mmol/L & source of infection as pneumonia.

Official Title
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Comparison of National Early Warning Score (NEWS) & Sepsis Patient Evaluation in the Emergency Department (SPEED) for The Early Identification of Sepsis in the Emergency Department

Conditions
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Sepsis Scores

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age of 18 - 80 years. Patients of both genders. Exclusion Criteria: Patient refusal . Accepts Healthy Volunteers . Aged below 18 years

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mortality . | Mortality during the 30 day follow-up. | 30 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Hospital admission . | Admission to hospital from the Emergency Department. | Day 0 | 
| ICU/HDU admission . | Admission to the Intensive Care Unit or High Dependency Unit from the Emergency Department . | Day 0 | 
| Readmission in the ED . | Re-visits to the ED after the index-visit . | Hour 72, Day 30 |