Strength and Range of Motion in Women Undergoing Surgery for Breast Cancer

Study Overview
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Brief Summary
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RATIONALE: Gathering information about strength and range of motion over time from women undergoing surgery for breast cancer may help doctors learn more about recovery from surgery and on-going care. PURPOSE: This clinical trial is collecting information about strength and range of motion over time from women undergoing surgery for breast cancer.

Detailed Description
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OBJECTIVES: Collect data regarding diagnosis, type of surgery, receipt of adjuvant therapy, age, height, weight, waist circumference, arm strength, grip strength, shoulder range of motion, and physical activity participation from women undergoing surgery for breast cancer. Examine changes in physical activity participation, measures of body composition, shoulder range of motion, grip strength, and arm strength over time in these patients. Determine differences in changes in physical activity and indices of fitness according to type of surgery and adjuvant therapy. Examine relationships between exercise participation, fitness, and body composition over time. Correlate data with an ongoing randomized exercise trial that includes strength and flexibility assessments with no pre-surgery measures. OUTLINE: This is a prospective, cohort study. Patients submit data comprising demographic/medical information, anthropometrics (weight, height, waist circumference), grip strength, bicep strength, shoulder range of motion, and physical activity participation prior to surgery, at each surgical follow-up visit, and at 2 years after surgery.

Official Title
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Breast Clinic Strength and Range of Motion Study

Conditions
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Breast Cancer

Intervention / Treatment
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* Other: physiologic testing


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Diagnosis of breast cancer Stage I-IV disease Planning to undergo surgery at the Comprehensive Cancer Center Breast Clinic at Wake Forest University Baptist Medical Center

Ages Eligible for Study
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Maximum Age: 120 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: physiologic testing|physical testing of range of motion, grip strength etc.|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Collection of data before surgery, at each follow-up visit, and at 2 years after surgery |  | approximately 2 years | 
| Changes in physical activity participation, measures of body composition, shoulder range of motion, grip strength, and arm strength over time |  | approximately 2 years | 
| Differences in changes in physical activity and indices of fitness according to type of surgery and adjuvant therapy |  | approximately 2 years | 
| Relationships between exercise participation, fitness, and body composition over time |  | approximately 2 years | 
| Correlation of data with an ongoing randomized exercise trial that includes strength and flexibility assessments with no pre-surgery measures |  | approximately 2 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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long-term effects secondary to cancer therapy in adults, recurrent breast cancer, stage I breast cancer, stage II breast cancer, stage IIIA breast cancer, stage IIIB breast cancer, stage IIIC breast cancer, stage IV breast cancer