Computer-based Treatment of Dysfunctional Beliefs in Depressive Inpatients

Study Overview
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Brief Summary
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The aim of the present study is to investigate whether confronting depressive patients with their dysfunctional core beliefs via a computer program results in a reduction of the patients' dysfunctional beliefs. Patients will be presented with a virtual agent confronting them with their dysfunctional core beliefs (e.g. You are worthless). Participants will be instructed to contradict these virtual agents (e.g. That's not true, I'm a wonderful person).

Detailed Description
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The aim of the present study is to investigate whether confronting depressive patients with their dysfunctional core beliefs via a computer program results in a reduction of the patients' dysfunctional beliefs. Participants will randomly be assigned to the experimental or control group. In the course of the study, experimental participants will be presented with a virtual agent confronting them with their dysfunctional core beliefs (e.g. You are worthless). Experimental participants will be instructed to contradict these virtual agents (e.g. That's not true, I'm a wonderful person). A group of inpatients (male/female) suffering from depression will participate in the study. The patients will be recruited at the Klinik und Poliklinik für Psychiatrie und Psychotherapie der Universität Regensburg am Bezirksklinikum Regensburg. The study will be divided into five sessions taking place on consecutive days. Furthermore, there will be a follow-up. Session 1: In the course of this session participants will be informed about the experimental procedure and sign an informed consent. Exclusion criteria will be assessed via self-report and by consulting the responsible therapist. Participants will be asked to fill in the German version of the Beck Depression Inventory-II and German version of the Dysfunctional Attitude Scale. The experimenter will explain the concept of dysfunctional core beliefs to the participants and give examples. Participants will be asked to write down three individual core beliefs (e.g. I'm worthless) and to rate how much they believe in each of these three core beliefs (on a scale ranging from 0% to 100%). Furthermore, participants will be asked to write down alternative beliefs for each of the three core beliefs and to rate (on a scale ranging from 0% to 100%) how much they believe in these alternative beliefs. Sessions 2 to 4 (intervention): During these sessions, the experimental participants will be seated in front of a computer. The experimenter will read aloud the participants' core beliefs with the virtual agent on the computer screen moving his lips accordingly. Thus, participants will get the impression of the agent speaking to them. Participants will be instructed to contradict the agent. There will be 10 trials per core belief (30 trials per session, 90 trials in total). At the end of each session, participants will be asked to rate how much they believe in each of their core beliefs as well as in each of their alternative beliefs. Furthermore, they will be asked to rate (on a scale ranging from 0% to 100%) how hard it was for them to contradict the virtual agent. Control subjects will not undergo sessions 2 to 4. Session 5: Participants will fill in the German version of the Beck Depression Inventory-II and the German version of Dysfunctional Attitude Scale and give a conviction rating for each of their three core beliefs and each of their alternative beliefs. Follow-up (after two weeks): Participants will fill in the German version of the Beck Depression Inventory-II and the German version of the Dysfunctional Attitude Scale and give a conviction rating for each of their three core beliefs and each of their alternative beliefs.

Official Title
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Computer-based Treatment of Dysfunctional Beliefs in Depressive Inpatients

Conditions
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Depression

Intervention / Treatment
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* Behavioral: computer-based confrontation with dysfunctional beliefs


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: • diagnosis of a depressive disorder Exclusion Criteria: substantial and imminent suicide risk current psychotic symptoms history of psychotic symptoms current manic episode current diagnosis of alcohol or drug abuse or dependence hearing problems poor eyesight pregnancy

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: confrontation group<br>computer-based confrontation with dysfunctional beliefs | Behavioral: computer-based confrontation with dysfunctional beliefs<br>* Patients will be presented with a virtual agent confronting them with their dysfunctional core beliefs (e.g. You are worthless). Participants will be instructed to contradict these virtual agents (e.g. That's not true, I'm a wonderful person).<br>|
| No Intervention: control group<br>no computer-based confrontation with dysfunctional beliefs | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| change in the score on the Dysfunctional Attitude Scale | change in the score (ranging from 40 to 280 with higher scores indicating more dysfunctional attitudes) on the German version of the Dysfunctional Attitude Scale | at baseline, one day after the end of the intervention, at follow-up (2 weeks after the end of the intervention) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| change in the conviction ratings for the dysfunctional beliefs | Participants will be asked to rate (on a scale ranging from 0% to 100%) how much they belief in their dysfunctional beliefs | at baseline, one day after the end of the intervention, at follow-up (2 weeks after the end of the intervention) | 
| change in the conviction ratings for the alternative beliefs | Participants will be asked to rate (on a scale ranging from 0% to 100%) how much they belief in their alternative beliefs | at baseline, one day after the end of the intervention, at follow-up (2 weeks after the end of the intervention) | 
| change in the score on the Beck Depression Inventory-II | change in the score (ranging from 0 to 63 with higher scores indicating more severe depressive symptoms) on the German version of the Beck Depression Inventory-II | at baseline, one day after the end of the intervention, at follow-up (2 weeks after the end of the intervention) |