Merits of Continuous Paravertebral Block in the Management of Renal/Adrenal Surgery by Laparotomy

Study Overview
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Brief Summary
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The paravertebral block is an alternative in the analgesia epidural the major interest of which lives in the catheterisation of the paravertébral space allowing to assure/insure an one-sided continuous analgesia. The main objective of the study is to bring to light the superiority of the continuous paravertébral block, as a supplement to analgesia, in the care of the renal and\or adrenal surgery by laparotomy at the adult in terms of consumption of morphine, with regard to the classic analgesia classic. The main assessment criterion is the consumption of morphine within first 24 postoperative hours at the patients benefiting from a paravertébral continuous block besides the classic systematic analgesia.

Official Title
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Consideration of the Merits of Continuous Paravertebral Block in the Management of Renal and/or Adrenal Surgery by Laparotomy in Adults

Conditions
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Indication for Renal and/or Adrenal Surgery

Intervention / Treatment
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* Procedure: Continuous Paravertebral block


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age > 18 years Patient scheduled for renal and/or adrenal surgery American Society of Anesthesiologists score ASA I, II, III Written informed consent given by the patient Exclusion Criteria: Contraindication in the loco-regional anesthesia in the products of local anesthetic Surgery as a matter of urgency Pregnancy Congestive Cardiac insufficiency Severe hepatic Incapacity Disturbs of the coagulation Age < 18 years ASA IV Patient already participating in a study or deadline 3-month-old subordinate since the end of a previous study Under guardianship Patient Psychiatric pathology or limitation of the intellectual abilities making difficult the understanding of the subjective questions.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Continuous Paravertebral block<br>Continuous Paravertebral block | Procedure: Continuous Paravertebral block<br>* The paravertébral block is a peripheral block which gets an one-sided continuous analgesia by infiltration of the spinal nerves which appear from the intervertebral foramen. Its realization consists of a draining in 2-3 cm of the thorny apophyses ( T6-T8). During the perception of the osseous contact (cross-functional process of the vertebra), the needle is redirected in cephalic direction until a loss of resistance corresponding to the passage of the upper costo-cross-functional ligament that is in the entrance to the paravertébral space. A catheter is then inserted into the paravertébral space.<br>|
| Placebo Comparator: Placebo<br>Placebo | Procedure: Continuous Paravertebral block<br>* The paravertébral block is a peripheral block which gets an one-sided continuous analgesia by infiltration of the spinal nerves which appear from the intervertebral foramen. Its realization consists of a draining in 2-3 cm of the thorny apophyses ( T6-T8). During the perception of the osseous contact (cross-functional process of the vertebra), the needle is redirected in cephalic direction until a loss of resistance corresponding to the passage of the upper costo-cross-functional ligament that is in the entrance to the paravertébral space. A catheter is then inserted into the paravertébral space.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| morphine consumption during the first 24 hours |  | 24 hours | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Paravertebral block, loco regional anesthesia, renal surgery, PCA morphine