PECO Air Purification in Hospital Rooms to Improve Health Outcomes for Pediatric Respiratory Distress

Study Overview
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Brief Summary
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This study will investigate the efficacy of a novel air purification technology, Photo Electrochemical Oxidation (PECO), has on pediatric patients hospitalized for respiratory distress. The study will take place at Mercyhealth Hospital - Rockton Avenue where all 23 pediatric rooms will be outfitted with portable PECO air purifying units. The main outcomes are the length of stay and progression to ICU, which will be compared with historical controls.

Detailed Description
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The goal of this study is to assess whether using PECO to purify air in a hospital can improve health outcomes for pediatric patients with respiratory distress. The results of this study will be used in three primary ways: As evidence to support an installation of PECO in hospital HVAC systems to improve the standard of care for patients with respiratory distress Towards dissemination efforts through publication in a peer-reviewed journal and presentation at national and international conferences For informing healthcare providers and stakeholders There are no plans to repeat this study with other hospital partners

Official Title
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Use of PECO Air Purification in Hospital Rooms to Improve Health Outcomes for Pediatric Respiratory Distress

Conditions
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Asthma, Respiratory Distress Syndrome, Pneumonia

Intervention / Treatment
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* Device: Photo Electrochemical Oxidation (PECO) for Air Purification


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All pediatric patients who are admitted to the Mercyhealth Hospital - Rockton Avenue following the Start Date and have infectious or non-infectious respiratory distress as defined by the following ICD codes will be included in the study: J00-J06: Acute upper respiratory infections J09-J18: Influenza and pneumonia J20-J22: Other acute lower respiratory infections J30-J39: Other diseases of upper respiratory tract J40-J47: Chronic lower respiratory diseases J60-J70: Lung diseases due to external agents J80-J84: Other respiratory diseases principally affecting the interstitium J85-J86: Suppurative and necrotic conditions of the lower respiratory tract J90-J94: Other diseases of the pleura J95-J95: Intraoperative and postprocedural complications and disorders of respiratory system, not elsewhere classified Exclusion Criteria: Any patient admitted to the NICU Patients in the ER only Any patient with non-respiratory conditions Adults

Ages Eligible for Study
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Minimum Age: 1 Year
Maximum Age: 17 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: PECO<br>All pediatric patients admitted for respiratory distress will have the intervention of Photo Electrochemical Oxidation (PECO) for Air Purification. | Device: Photo Electrochemical Oxidation (PECO) for Air Purification<br>* PECO air purifiers from Molekule will be placed in every patient room. Health metrics will be tracked for patients whose diagnosis is respiratory distress.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Length of stay | Total length of hospital stay for patient | 5 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Readmission rate | Rate of readmission within 30 days of discharge | 1 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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asthma, environmental intervention, respiratory distress, pediatric hospitalization, pneumonia, bronchiolitis