Depression Online Assessment and Therapy

Study Overview
=================
Brief Summary
-----------------
One Aim of the current study is to better understand why some patients suffering from depression do not seek professional help by doctors but in the internet. Furthermore patients with depression will receive Online Therapy for depression. Aim of this part of the study is to investigate whether quality of life changes accordingly to improvement of symptoms after online therapy.

Detailed Description
-----------------
German speaking patients can register online. There will be no side visits. After screening: patients which meet inclusion criteria and no exclusion criteria can take part in online therapy for depression. After 12 weeks 2nd online survey. After this survey patients can use the program the following 6 months (follow-up) After 6 months 3rd and last online-survey. According to the aims of the study cross-sectional as well as longitudinal data will be obtained and analysed

Official Title
-----------------
Online Assessment for Therapy Expectation and Quality of Life and Online Therapy of Depression

Conditions
-----------------
Depression

Intervention / Treatment
-----------------
* Other: Mail support
* Other: no mail support


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: German language depression at least slight according BDI (Beck depression inventory) and at least 2 weeks Exclusion Criteria: severe depression according BDI suicidal ideation alcohol or drug dependency history of psychotic symptoms history of bipolar disorder or previous mania current in-patient care or semi-residential treatment

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Screening
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: no mail support<br>no mail support during follow-up | Other: no mail support<br>* follow-up without mail support<br>|
| Other: mail support<br> | Other: Mail support<br>* between post treatment and follow up two groups: one with unspecific mail support every 2 weeks one without<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change of Quality of life | WHOQol brev - WHO quality of life questionnaire short form | at screening, post treatment (3 months) and follow-up (6 months after post) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| change of Sleep quality | Questionnaire PSQI - Pittsburgh sleep quality index | screening, post treatment (3 months), follow-up(6 months after post) | 
| change of severity of depression | patients receive mail support or not during follow up. Questionnaire: BDI - Beck Depression Inventory | 3 time points screening, + 3 months + 6 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
depression, online therapy, cognitive behavioural therapy, quality of life, alexithymia, therapy expectation and satisfaction