Application of LARS Ligament in Bone Prosthesis Replacement

Study Overview
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Brief Summary
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This is a single-center, prospective, real-world observational study designed to enroll all patients eligible for enrollment. Basic data, treatment methods, postoperative complications and limb function were collected. The differences in postoperative complications, postoperative limb function and so on between patients who underwent LARS ligament implantation and bone prosthesis replacement (ligament group) and patients who underwent bone prosthesis replacement (control group) were compared.

Detailed Description
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This is a single-center prospective real-world observational study of 100 eligible patients with bone tumors who are scheduled to undergo LARS ligament implantation and/or bone prosthesis replacement in Henan Cancer Hospital in the next 10 years. Basic data, treatment methods, postoperative complications and limb function were collected. The differences in postoperative complications, postoperative limb function and so on between patients who underwent LARS ligament implantation and bone prosthesis replacement (ligament group) and patients who underwent bone prosthesis replacement (control group) were compared.

Official Title
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A Prospective, Real-world, Single-center, Cohort Study of LARS Ligaments in Bone Tumors

Conditions
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Malignant Tumor

Intervention / Treatment
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* Other: LARS ligament and bone prosthesis replacement was performed


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Men and women of all ages are welcome. Pathologically confirmed in our hospital as a subtype of malignant tumor. He received LARS ligament and bone prosthesis replacement at our hospital. Exclusion Criteria: Not Applicable.
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| LARS ligament and bone prosthesis replacement was performed<br>To report the postoperative complications and limb function of patients who underwent LARS ligament and bone prosthesis replacement in Henan Cancer Hospital. | Other: LARS ligament and bone prosthesis replacement was performed<br>* To report the postoperative complications and limb function of patients who underwent LARS ligament and bone prosthesis replacement in Henan Cancer Hospital.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative complications | Complications of patients undergoing LARS ligament and bone prosthesis replacement. | From surgery to 24 months after surgery | 
| Limb function | Limb function was assessed using the Musculoskeletal Oncology Society (MSTS) scoring scale for seven items, namely movement, pain, stability, deformity, strength, functional activity, and emotional receptiveness. The highest possible score is 35, with 5 points allocated to each project. | Patients were enrolled until 24 months after surgery |