Factors Influencing the Risk of Surgical Site Infections and Wound Complications in Operatively Treated Ankle Fractures in the Elderly

Study Overview
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Brief Summary
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This study is to analyse risk factors for wound complications or surgical site infections and to analyse whether risk factors for wound complications or surgical site infections are also factors for other complications. Based on the data from this study it will be investigated whether a risk score can be build up to predict individual risk for a complication after surgery.

Official Title
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Factors Influencing the Risk of Surgical Site Infections and Wound Complications in Operatively Treated Ankle Fractures in the Elderly - a Case Control Study

Conditions
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Ankle Fractures

Intervention / Treatment
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* Other: Data collection from routine medical records


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients ≥ 50 years with ankle fractures surgically treated at the University Hospital Basel Sufficient Follow up at the University Hospital Basel in order to judge wound healing complications over a 4 weeks period and fracture related infection over a 3 months period Exclusion Criteria: Existence of a documented dissent. Distal tibia fractures and Pilon fractures Followed up at another institution or with no follow up at our institution for any other reason

Ages Eligible for Study
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Minimum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| case cohort<br>Patients with a surgical site infection or a wound complication after surgical treatment of an ankle fracture. The time horizon for wound complication was set to maximally 4 weeks after surgery. | Other: Data collection from routine medical records<br>* Data collection from routine medical records for criteria for fracture related infections (FRI) and for wound complications. Data collection from routine medical records for risk factors.<br>|
| control cohort<br>Patients without a surgical site infection or a wound complication (normal wound-healing and suture or staple removal) after surgical treatment of an ankle fracture. | Other: Data collection from routine medical records<br>* Data collection from routine medical records for criteria for fracture related infections (FRI) and for wound complications. Data collection from routine medical records for risk factors.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| association between single risk factors and outcome (wound healing complication, surgical site infection) | In a first step analyses of the association between single risk factors and outcomes will be made. Odds ratios will be reported together with confidence intervals and p-values. In a second step it will be analyzed whether risk factors can be combined into a risk score using Tibshirani's Lasso. | at Baseline | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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surgical site infections, wound complications, operatively treated ankle fractures, delayed wound healing