Colorectal Cancer Prehabilitation in Changi General Hospital

Study Overview
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Brief Summary
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Cancer prehabilitation typically involves multiple pre-op visits. The investigators aim to assess the impact of their novel model, a one-stop service by a small, levelled-up core team on newly diagnosed colorectal cancer patients planned for surgery.

Detailed Description
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Objective Cancer prehabilitation typically involves multiple pre-op visits. The investigators aim to assess the impact of their novel model, a one-stop service by a small, levelled-up core team on newly diagnosed colorectal cancer patients planned for surgery. Design This is a before-after trial in a tertiary public hospital in Singapore, involving all newly diagnosed colorectal cancer patients planned for surgery who are referred to the Cancer Prehabilitation Program. The primary outcome measure is the 6-minute-walk-test. Others include physical, psychological, quality-of-life and post-operative measures, and patient-satisfaction-surveys, taken at baseline, pre-operatively (post-prehabilitation), and 3-months-post-operatively. Keywords: Colorectal; Cancer Prehabilitation; Novel; Model of Care

Official Title
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Colorectal Cancer Prehabilitation in Changi General Hospital

Conditions
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Colorectal Cancer

Intervention / Treatment
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* Other: Colorectal Cancer Prehabilitation Programme


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 1. All newly diagnosed colorectal cancer patients planned for surgery in Changi General Hospital, Singapore Exclusion Criteria: 1. Patients' refusal to participate

Ages Eligible for Study
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Minimum Age: 21 Years
Maximum Age: 99 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Intervention Model: Single Group Assignment
Interventional Model Description: before-after trial
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Colorectal Cancer Prehabilitation Program<br>This is a before-after trial. The same group of participants will have a series of outcome measures taken at baseline, which will then be compared to these same outcome measures when repeated after undergoing prehabilitation and at 3 months' post-operatively | Other: Colorectal Cancer Prehabilitation Programme<br>* Assessment and Interventions involving the Prehabilitative domains of medical optimisation, exercise prescription, nutrition and mental health optimisation<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 6-minute-walk-test | Distance walked in 6 minutes under standardised conditions | Baseline | 
| 6-minute-walk-test | Distance walked in 6 minutes under standardised conditions | Pre-Operatively (after prehabilitation) | 
| 6-minute-walk-test | Distance walked in 6 minutes under standardised conditions | Post-Operatively (3 months) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 30-second-sit-to-stand-test | Number of repetitions of sit-to-stand within 30 seconds | Baseline | 
| 30-second-sit-to-stand-test | Number of repetitions of sit-to-stand within 30 seconds | Pre-Operatively (after prehabilitation) | 
| 30-second-sit-to-stand-test | Number of repetitions of sit-to-stand within 30 seconds | Post-Operatively (3 months) | 
| Hospital Anxiety and Depression Scale | Divided into Anxiety (0-21 points) and Depression scale (0-21 points), the higher the worser | Baseline | 
| Hospital Anxiety and Depression Scale | Divided into Anxiety (0-21 points) and Depression scale (0-21 points), the higher the worser | Pre-Operatively (after prehabilitation) | 
| Hospital Anxiety and Depression Scale | Divided into Anxiety (0-21 points) and Depression scale (0-21 points), the higher the worser | Post-Operatively (3 months) | 
| EuroQol- 5 Dimension | Health Score (visual analogue scale from 0-100), the higher the better | Baseline | 
| EuroQol- 5 Dimension | Health Score (visual analogue scale from 0-100), the higher the better | Post-Operatively (3 months) | 
| Post-Operative Hospital Length of Stay | Post-Operative Hospital Length of Stay | From Date of Admission for Surgery till Date of Discharge, assessed up to 100 weeks | 
| 30-Day Post-Operative Major Complications | 30-Day Post-Operative Major Complications | From Surgery till 30 Days Post-op | 
| 30-Day Post-Operative Readmission Rates | 30-Day Post-Operative Readmission Rates | From Surgery till 30 Days Post-op | 
| 30-Day Post-Operative Mortality | 30-Day Post-Operative Mortality | From Surgery till 30 Days Post-op | 
| Patient Satisfaction Survey | Patient Satisfaction Survey | Pre-Operatively (after prehabilitation) | 
| Patient Satisfaction Survey | Patient Satisfaction Survey | Post-Operatively (3 months) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Model of Care, Colorectal, Cancer Prehabilitation, Novel