Dismantling Exposure, Relaxation, and Rescripting Therapy

Study Overview
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Brief Summary
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The purpose of this case series dismantling study is to extend previous findings regarding the efficacy of a brief treatment for chronic post-trauma nightmares by examining the dose effect and mechanism of change. Exposure, relaxation, and rescripting therapy (ERRT) is a promising psychological intervention developed to target trauma-related nightmares and sleep disturbances. ERRT has exhibited strong support in reducing the frequency and intensity of nightmares, as well as improving overall sleep quality in both civilian and veteran samples. In addition, significant decreases in PTSD and depression symptoms have been reported following treatment (Davis et al., 2011; Davis & Wright, 2007; Long et al., 2011; Swanson, Favorite, Horin, & Arnedt, 2009). ERRT is currently an evidence-level B suggested treatment (Cranston, Davis, Rhudy, & Favorite, 2011). Despite this evidence, the mechanism of change for ERRT remains unclear. We propose to conduct a set of case series in order to examine the possible mechanisms: psycho-education, dose response for exposure, and no exposure components of the treatment. Each part of the treatment is theorized to contribute to the improved treatment outcome and it is hypothesized that participants will benefit no matter what group they are in. All participants will receive 5 to 6 treatment sessions, conducted once per week for about 90 minutes, of a modified version of ERRT.

Official Title
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Exposure, Relaxation, Rescripting Therapy (ERRT) Dismantling

Conditions
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Frequent Trauma-related Nightmares

Intervention / Treatment
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* Behavioral: Exposure, Relaxation, and Rescripting Therapy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 18 years of age or older at the time of the intake, experienced a traumatic event, as defined by the Diagnostic and Statistical Manual (DSM-5), have approximately one nightmare each week for the past month be able to read and speak English. Exclusion Criteria: age of 17 or younger acute or apparent psychosis unmedicated bipolar disorder intellectual disability active suicidality, recent parasuicidal behaviors untreated substance use disorder in past 6 months

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: ERRT - Enhanced Exposure<br>Exposure, Relaxation, and Rescripting Therapy, 5 sessions, with enhanced exposure techniques | Behavioral: Exposure, Relaxation, and Rescripting Therapy<br>* Brief cognitive behavioral treatment targeting trauma-related nightmares and sleep problems<br>* Other names: ERRT;|
| Active Comparator: ERRT - Sleep and Relaxation<br>Exposure, Relaxation, and Rescripting Therapy protocol, 5 sessions, focused on sleep and relaxation | Behavioral: Exposure, Relaxation, and Rescripting Therapy<br>* Brief cognitive behavioral treatment targeting trauma-related nightmares and sleep problems<br>* Other names: ERRT;|
| Active Comparator: ERRT-Rescription<br>Exposure, Relaxation, and Rescripting Therapy, 5 sessions, with rescription but no exposure | Behavioral: Exposure, Relaxation, and Rescripting Therapy<br>* Brief cognitive behavioral treatment targeting trauma-related nightmares and sleep problems<br>* Other names: ERRT;|
| Active Comparator: ERRT-Sleep<br>Exposure, Relaxation, and Rescripting Therapy, 5 sessions, with enhanced sleep techniques | Behavioral: Exposure, Relaxation, and Rescripting Therapy<br>* Brief cognitive behavioral treatment targeting trauma-related nightmares and sleep problems<br>* Other names: ERRT;|
| Active Comparator: ERRT - Consensus Manual<br>Consensus Protocol, 6 sessions, includes components of ERRT and other nightmare protocols. | Behavioral: Exposure, Relaxation, and Rescripting Therapy<br>* Brief cognitive behavioral treatment targeting trauma-related nightmares and sleep problems<br>* Other names: ERRT;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Nightmare Frequency Past Week | This fill-in-the-blank variable assesses the number of nights the individual experienced nightmares in the past week (range = 0 - 7 nights). Higher values indicate more nights with nightmares (worse outcome). | up to 6 months followup | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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ERRT, Nightmares, Sleep, Trauma, PTSD