Fit in the Aged by Professional Training

Study Overview
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Brief Summary
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This intervention study tests training methods to stabilize or improve functionality in the high risk group of prefrail elderly persons.

Detailed Description
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This study aims at the improvement of muscular function by physical exercise in prefrail elderly persons. Prefrail participants are recruited according to the frailty score of Fried. Taking into account, that vitamin D supplementation reduces falls and improves muscle strength in older people, all participants are supplemented by vitamin D. Two different training methods are tested. After a run-in period of supplementation of vitamin D for two months, participants will be randomized into three different equally sized groups (n=25): Group A will receive power training. Group B will have progressive strength training. Group C will serve as a control group. They will receive a consultation about leading a healthy life with special attention being paid to nutrition and physical activity. The intervention period lasts for 12 weeks. The 60 minutes training sessions will be held two times a week by members of the Institute of Sport Science and Sports of the University of Erlangen-Nuremberg. Follow-up visits are scheduled three and six months after intervention period.

Official Title
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The Effect of Different Training Modalities and Vitamin D Supplementation on Functionality in Prefrail Elderly Persons

Conditions
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Frailty, Sarcopenia

Intervention / Treatment
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* Procedure: Power Training
* Procedure: Strength Training
* Other: Control


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Prefrailty according to the frailty score of Fried Exclusion Criteria: Sarcoidosis Nephrolithiasis Plasmacytoma COPD Inflammatory bowel disease Rheumatoid arthritis History of cancer Instable heart disease Depression (GDS>=6) Dementia (MMSE<=24) BMI>35kg/m² Current attendance of muscle training Medication: immunosuppressive drugs

Ages Eligible for Study
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Minimum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: A<br>Training I | Procedure: Power Training<br>* Power training, Vitamin D substitution<br>|
| Experimental: B<br>Training II | Procedure: Strength Training<br>* Strength training, Vitamin D substitution<br>|
| Active Comparator: C<br>Control | Other: Control<br>* Vitamin D substitution, Lifestyle consultation<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Short physical performance battery |  | 3 months after intervention | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Muscle strength and muscle power |  | 3 months after intervention | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Muscle power, Frailty, Exercise, Vitamin D