Impact of Time Intervals of Preparation on Quality and Tolerance of the Bowel Preparation

Study Overview
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Brief Summary
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The purpose of this study is to determine optimal time intervals for preparation before colonoscopy using different formulas.

Detailed Description
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Different formulas are used for bowel preparation before colonoscopy. Present guidelines are based on conventional polyethylene glycol. Their validity for other preparations were not evaluated. Relationship between length of preparation, interval to colonoscopy and bowel preparation quality, tolerance are assessed.

Official Title
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Impact of Time Intervals on Quality and Tolerance of the Bowel Preparation

Conditions
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Colonoscopy, Bowel Preparation

Intervention / Treatment
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* Procedure: Colonoscopy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: - subjects referred to diagnostic or therapeutic colonoscopy. Exclusion Criteria: ileus known or suspected bowel obstruction active bowel inflammation pregnancy any presence of serious medical conditions ( esp. cardiac, renal, liver diseases) history of prior colonic or rectal surgery inability to obtain valid data from

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 99 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Fortrans pulv. sol<br>Polyethylene glycol solution. Used 4 l before colonoscopy. Bowel preparation interval: QD/BID or one day. | Procedure: Colonoscopy<br>* The quality of bowel preparation, which is checked during colonoscopy<br>|
| Active Comparator: Picoprep pulv. sol.<br>Natrium picosulfate/ magnesium citrate solution. Used 2 l before colonoscopy. bowel preparation interval: QD/BID or one day. | Procedure: Colonoscopy<br>* The quality of bowel preparation, which is checked during colonoscopy<br>|
| Active Comparator: Moviprep pulv. sol.<br>Polyethylene glycol + ascorbic acid solution. Used 2 l before colonoscopy. Bowel preparation interval: QD/BID or one day. | Procedure: Colonoscopy<br>* The quality of bowel preparation, which is checked during colonoscopy<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Quality of bowel preparation according to time intervals of bowel preparation | The length of bowel preparation and interval to colonoscopy for bowel preparation quality Aronchick score excellent and good | One day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Tolerance of bowel preparation according to time intervals of bowel preparation |  | One day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Colonoscopy, Picosulfate sodium, Polyethylene glycol, Magnesium citrate, Ascorbic acid, SPMC (solution picosulfate + magnesium citrate), PEGA (Polyethylene glycol + ascorbic acid)