Chronic and Acute Effects of Resistance Exercise on Older Subjects' Blood Pressure

Study Overview
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Brief Summary
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The study aimed to evaluate the chronic and acute effects of high-intensity resistance training on blood pressure and its hemodynamic and neural determinators in healthy normotensive older subjects.

Detailed Description
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To investigate the chronic and acute effects of resistance training on blood pressure and its hemodynamic and neural determinators in elderly, 24 healthy normotensive older subjects were randomly divided into 2 groups: trained and control. The trained group was submitted a progressive high-intensity resistance training. Before and after 16 weeks, as well as, before and after the one training session, blood pressure (clinic and ambulatory), cardiac output (CO2 rebreathing), and autonomic modulation (spectral analysis of heart rate and blood pressure variabilities) were measured

Official Title
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Chronic and Acute Effects of Resistance Exercise on Older Subjects' Blood Pressure

Conditions
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Blood Pressure

Intervention / Treatment
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* Behavioral: Resistance training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 60 to 80 years Normotensives Nonactive Exclusion Criteria: Cardiovascular disease Cardiovascular medication Orthopedic problems

Ages Eligible for Study
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Minimum Age: 60 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Resistance training<br>Progressive high intensity resistance training performed twice a week for 16 weeks, and achieving in 7 exercises for the main muscles, the protocol of 4 sets of 6RM and 2 of 4RM. | Behavioral: Resistance training<br>* Progressive high intensity resistance training performed twice a week for 16 weeks, and achieving in 7 exercises for the main muscles, the protocol of 4 sets of 6RM and 2 of 4RM.<br>* Other names: strength training, weight training;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| blood pressure | Blood pressure was measured by auscultatory, oscillometric and photoplethysmographic device | 16 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| cardiovascular hemodynamics | cardiac output (CO2 rebreathing technique) | 16 weeks | 
| cardiovascular autonomic modulation | Spectral analysis of heart rate and blood pressure variabillity | 16 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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resistance training, blood pressure, hemodynamics, autonomic, Elderly Subjects