Antibacterial Effect of New Herbal Paste Used as an Intracanal Medication

Study Overview
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Brief Summary
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studying the antibacterial effect of Cosuts paste as an intracanal medication against Enterococcus faecalis that present in necrotic primary teeth

Detailed Description
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The children were randomly divided into two groups (I, II) Group I (N=12): using Costus-based paste as an intracanal medicament. Group II (N= 12): Calcium hydroxide iodoform paste (Metapex) as an intracanal medicament. Procedure: Access opening was started. then a swab was taken from the distal root canal with a dry paper point and transferred to a sterile test tube. The canals were filled with an intracanal medication according to the patient group. In group I, the canals was filled with a previously prepared Costus-based paste for one week, and In Group II, the canals were filled with Meta paste for one week. After 1 week, the paste was washed away from the canals then another swab was taken from the distal canal by a dry paper point as done before preoperatively. The 2 swabs were transferred within 2 hours to the lab for bacterial culture and detection of enterococcus faecalis count.

Official Title
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Antibacterial Effect of New Herbal Paste Used as an Intracanal Medication in Necrotic Primary Molars, a Randomized Control Trial

Conditions
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Infection Primary

Intervention / Treatment
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* Drug: herbal intracanal medication paste
* Drug: Meta paste


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients with clinically and radiologically diagnosed infected primary teeth in their mandibular arch. Teeth should be deeply carious, with a history of spontaneous pain and carious exposures with necrotic pulp was also be selected radiographic evidence of adequate alveolar bone support, and absence of internal or external resorption. tooth must be restorable. Exclusion Criteria: vital tooth Non restorable teeth

Ages Eligible for Study
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Minimum Age: 4 Years
Maximum Age: 10 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: randomized control trial
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Costus paste<br>Costus paste used as an intracanal medication for decreasing the number of enterococcus faecalis present in the necrotic root of the primary molar | Drug: herbal intracanal medication paste<br>* study the effect of costus herbal paste on enterococcus faecalis bacteria<br>* Other names: herbal paste;|
| Active Comparator: metapaste<br>metapaste used as an intracanal medication for decreasing the number of enterococcus faecalis present in the necrotic root of the primary molar | Drug: Meta paste<br>* compare the effect of Costus paste with meta paste in reducing the number of enterococcus faecalis<br>* Other names: control paste;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bacterial count | Colony forming unit | 1 weak | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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infected primary molars, metapaste, herbal paste