Effects of Hydrolyzed Collagen and Vitamin C on Explosive Performance

Study Overview
=================
Brief Summary
-----------------
Determine whether supplementation with a combined dose of 20 g of hydrolyzed collagen and 50 mg vitamin C, along with a power training exercise program, increases rate of force development (RFD) and performance in athletes

Official Title
-----------------
Effects of Hydrolyzed Collagen and Vitamin C on Explosive Performance

Conditions
-----------------
Collagen Synthesis, Rate of Force (RFD) Development

Intervention / Treatment
-----------------
* Dietary Supplement: Collagen and Vitamin C powder mix nutritional intervention
* Other: Maltodextrin placebo powder
* Other: Maximum power training exercise


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Healthy male athletes between 18-30 years of age Currently participating in sport <3 musculoskeletal injuries in the past year No health or dietary restriction that would be affected by the supplementation protocol Exclusion Criteria: History of more than 3 musculoskeletal injuries within the past 12 months Health, dietary restriction or diet that would be affected by the supplementation protocol Willing to eat similar dietary pattern the day before baseline testing and each exercise testing/intervention day

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 30 Years

Sexes Eligible for Study
-----------------
Male

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Hydrolyzed collagen and Vitamin C powder mix<br>20 g hydrolyzed collagen + 50 mg vitamin C (ascorbic acid) pre-packed powder diluted in 250 ml (8 oz) of water | Dietary Supplement: Collagen and Vitamin C powder mix nutritional intervention<br>* 20 g collagen + 50 mg vitamin C daily, 60 min prior to exercise<br>Other: Maximum power training exercise<br>* Explosive/power-based exercise training program 3 times/week at home consisting of drop jumps, box jumps, weighted jump squats loaded in a progressive manner weekly for 3 weeks. At baseline and at the end of each of the 3 weeks, measures of explosive performance are assessed in the lab (maximal isometric squat, counter-movement jump and squat jump)<br>|
| Placebo Comparator: Maltodextrin powder<br>20 g maltodextrin pre-packed powder diluted in 250 ml (8 oz) of water | Other: Maltodextrin placebo powder<br>* 20 g maltodextrin placebo daily, 60 min prior to exercise<br>Other: Maximum power training exercise<br>* Explosive/power-based exercise training program 3 times/week at home consisting of drop jumps, box jumps, weighted jump squats loaded in a progressive manner weekly for 3 weeks. At baseline and at the end of each of the 3 weeks, measures of explosive performance are assessed in the lab (maximal isometric squat, counter-movement jump and squat jump)<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Maximal rate of force development (RFD) of isometric squat (MIS) | Force (N) over time (msec) for the maximum slope of the first 20% of the movement | % change from baseline to week 1, week 2 and week 3 | 
| Counter-movement jump (CMJ) rate of force development (RFD) | CMJ jump performance N/s/kg | % change from baseline to week 1, week 2 and week 3 | 
| Squat jump height rate of force development (RFD) | Squat jump height performance RFD/kg | % change from baseline to week 1, week 2 and week 3 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
exercise, performance, athletes