Long-term Outcome Following Concomitant Surgical Ablation for Atrial Fibrillation at University Hospital Basel: A Retrospective Study

Study Overview
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Brief Summary
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This retrospective single-centre study aims to examine the success rate of concomitant surgical ablation in patients with atrial fibrillation (AF) with an up to eight years follow-up period. Moreover, the focus of this study was to identify variables which predict freedom from AF, such as the type of AF, lesion set performed, energy source used and the patient's characteristics.

Official Title
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Long-term Outcome Following Concomitant Surgical Ablation for Atrial Fibrillation at University Hospital Basel: A Retrospective Study

Conditions
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Atrial Fibrillation, Maze Procedure

Intervention / Treatment
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* Procedure: Surgical Ablation for Atrial Fibrillation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: concomitant surgical ablation for atrial fibrillation performed between January 2011 and January 2017 at University Hospital Basel Exclusion Criteria: stand-alone procedure surgical ablation for atrial flutter
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: Surgical Ablation for Atrial Fibrillation|Surgical ablation in combination with other cardiac procedures through a median sternotomy or thoracotomy. Main procedures were valve surgery (i.e. repair, replacement) and/or coronary artery bypass grafting (CABG). Surgical ablation procedures for atrial fibrillation were divided into three different groups according to Heart Rhythm Society (HRS) expert consensus 2017: (1) Pulmonary vein isolation alone; (2) Pulmonary vein isolation combined with left atrial lesion sets; (3) and biatrial procedure.|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Freedom from AF one year after surgical ablation | one-year success | 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Freedom from atrial fibrillation (AF) and atrial flutter (AFL) after removal from antiarrhythmic drug therapy |  | from surgical ablation until 10th October 2019 | 
| Need of additional arrhythmia interventions | repeat ablation procedures, electrical cardioversion, pacemaker implantation or implantable cardioverter-defibrillator (ICD) implantation | from surgical ablation until 10th October 2019 | 
| Use of oral anticoagulation |  | from surgical ablation until 10th October 2019 | 
| Perioperative morbidity |  | from surgical ablation until 10th October 2019 | 
| Mortality |  | from surgical ablation until 10th October 2019 | 
| Evolution of left atrial size |  | from surgical ablation until 10th October 2019 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Surgical Ablation, Cardiac Surgery