Impact of Caregiver Beliefs on Adherence to Antipsychotic Medications in Patients With Schizophrenia

Study Overview
=================
Brief Summary
-----------------
Only one third of patients with schizophrenia are observant to their treatment knowing that the lack of adherence to treatment is one of the most important predictors of relapse. Recent work shows that the erroneous or negative beliefs of patients with schizophrenia regarding antipsychotic treatment are associated with poor compliance. The hypothesis is that negative beliefs about the antipsychotic treatment of caregivers of patients with schizophrenia may be associated with a higher risk of poor compliance compared to caregivers with positive beliefs about treatment. The primary purpose is to explore the correlation between caregiver beliefs about treatment and patient compliance, taking into account the level of caregiver-patient link.

Detailed Description
-----------------
Non-interventional cross-sectional exploratory study with a single visit for patients with schizophrenia and their caregivers, who agreed to participate in the protocol.

Official Title
-----------------
Impact of Caregiver Beliefs on Adherence to Antipsychotic Medications in Patients With Schizophrenia

Conditions
-----------------
DSM-5 Schizophrenia

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patient over 18 years old With a diagnosis of schizophrenia according to DSM-5 criteria Accompanied by his main caregiver, who will be able to complete the questionnaires after having signed the information form. Treated with one or more antipsychotics. Able to complete the questionnaires related to the protocol Having agreed to sign the information form. Exclusion Criteria: Not understanding French, unable to answer questions linguistically Presenting an organic pathology and / or cognitive deterioration likely to hinder a good understanding of the interview Having already participated in the study presenting disorders related to the use of substances of severe intensity (such as acute intoxication, withdrawal syndrome or any state of delirium)

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients and caregivers<br>Patients suffering from schizophrenia accompanied by their caregiver | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Assessment of the correlation between caregiver beliefs about treatment and patient compliance | The caregiver beliefs are evaluated by the Beliefs about Medicines Questionnaire, the patient compliance is evaluated by the investigator with Behaviourally Anchored Rating Scales and by the patient him-self with Morisky Medication Adherence Scale, and the level of caregiver-patient link is evaluated with Involvement Evaluation Questionnaire. | At day 1 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
schizophrenia, beliefs, caregiver