Effects of Exercise in the Functional Capacity, Central Artery and Rigidity Ankle Brachial Index

Study Overview
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Brief Summary
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The Peripheral Arterial Disease prevalence is around 3-10 % of the world population. Exercise plays an important role in treating these patients.

Detailed Description
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Objective: To investigate the effects of training Combined Aerobic - Strength versus aerobic functional capacity, ankle brachial index (ABI ) and central arterial stiffness in patients with peripheral arterial disease

Official Title
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Effects of Combined Force Training Aerobic Versus Aerobic in the Functional Capacity, Central Artery and Rigidity Ankle Brachial Index in Patients With Peripheral Artery Disease

Conditions
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Peripheral Arterial Disease

Intervention / Treatment
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* Other: Device: treadmill
* Other: Device: treadmill Train_Comb_aerobic


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Diagnosis of DAP and CI . Stage I or II of Fontaine . intermittent claudication symptoms for at least 3 months with ankle brachial index (ABI ) at rest ≤ 0.90 in 1 or 2 legs. Exclusion Criteria: Ischemia criticism in one of the lower limbs. moderate or severe ulcers on one of the lower limbs.Orthopedic issues that prevent pratical of the exercises or conducting evaluations . Participation in other studies with rehabilitation. decompensated hypertension . decompensated diabetes . Cardiovascular events less than three months . severe lung disease .

Ages Eligible for Study
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Minimum Age: 40 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Device: treadmill<br>Aerobic training on a treadmill continuously with speed and wave periodization. Frequency twice per week ( 2x ) for twelve weeks | Other: Device: treadmill<br>* Aerobic training on a treadmill continuously with speed and wave periodization. Frequency twice per week ( 2x ) for twelve weeks. Device: treadmill.<br>|
| Active Comparator: Device: treadmill Train_Comb_aerobic<br>strength training with free weights, followed by active recovery on a treadmill with fixed intervals of 60 to 120 seconds between each workforce of series. | Other: Device: treadmill Train_Comb_aerobic<br>* Device: treadmill Train_Comb_aerobic. strength training with free weights, followed by active recovery on a treadmill with fixed intervals of 60 to 120 seconds between each workforce of series. Device: treadmill Train_Comb_aerobic<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cardiopulmonary test - 6 minute walk test | evaluation of functional capacity | 48 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pulse wave velocity |  | 48 months | 
| One maximum repetition test |  | 48 months | 
| ankle brachial index |  | 48 months | 
| Edinburgh Claudication Questionnaire |  | 48 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Peripheral Arterial Disease, exercise