Smallest Significant Value in Osteodensitomery in an Obese Population

Study Overview
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Brief Summary
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The aim of this study is to determined the smallest significant value in osteodensitometry in obese population. The study population will be divided in 3 groups according to their BMI. Bone mineral density will be measured twice in osteodensitometry, then the smallest significant value will be determined. Our hypothesis is that the smallest significant value that we use in an non-obese population can be different in an obese population.

Detailed Description
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The aim of this study is to determined the smallest significant value in osteodensitometry in obese population. There will be at least 120 patient included. The study population will be divided in 3 groups according to their BMI : the first group has a BMI between 30 and 35 kg/cm² ; the second group has a BMI between 35 et 40 kg/cm² ; and the third group has a BMI over 40 kg/cm². Patients will be referred by their doctors (rheumatologist and others) to evaluate their bone mineral density in osteodensitometry at CHU of Reims. Patients will be informed of the aim of the study by the prescriptor of the osteodensitometry. The osteodensitometry will be executed by a nurse. Patients will have to complete a questionnaire about their medical history and their medications. Bone mineral density will be measured twice in osteodensitometry, at the lumbar spine, the hip and the femur. This exam lasts approximately 40 minutes. Then the smallest significant value will be determined by comparing each measure for every patients.

Official Title
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Smallest Significant Value in Osteodensitomery in an Obese Population

Conditions
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Obesity

Intervention / Treatment
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* Other: Bone mineral density


Participation Criteria
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Eligibility Criteria
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Inclusion criteria : Major patients Patients referred to the CHU of Reims to make an osteodensitometric evaluation of their bone mineral density BMI > 30 kg/cm² Patient affiliated to a health insurance plan Patients who have signed informed consent Exclusion criteria : Minor patients Pregnant women Patients protected by the law

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Obese patient<br> | Other: Bone mineral density<br>* Bone mineral density will be measured twice in all included patients.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| osteodensitometry in obese population | smallest significant value in osteodensitometry in obese population | Day 1 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| osteodensitometry in obese population with BMI between 30 and 35 kg/cm² | smallest significant value in osteodensitometry in obese population with BMI between 30 et 35 kg/cm² | Day 1 | 
| osteodensitometry in obese population with BMI between 35 and 40 kg/cm² | smallest significant value in osteodensitometry in obese population with BMI between 35 et 40 kg/cm² | Day 1 | 
| osteodensitometry in obese population with BMI over 40 kg/cm² | Smallest significant value in osteodensitometry in obese population with BMI over 40 kg/cm² | Day 1 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Bone density, Osteoporosis, Osteopenia, Obesity, OSteodensitometry