Evaluation of the Effect of the Dietary Supplement X34 on Skin Radiance of Healthy Volunteers With Dull Complexion

Study Overview
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Brief Summary
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The main objective of this trial is to evaluate the effect of the daily dose of X34 dietary supplement on skin radiance (clinical assessment) for 8 weeks.

Official Title
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Evaluation of the Effect of the Dietary Supplement X34 on Skin Radiance of Healthy Volunteers With Dull Complexion

Conditions
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Healthy Volunteers

Intervention / Treatment
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* Dietary Supplement: X34


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Female volunteers: Age: 40-70 years Who have a dull complexion evaluated by clinical scoring Phototype II to IV (annex 5) Non-smoking or smoking less than 5 cigarettes per day Did not change her eating habits, within one month before the start of the study and agreeing not change during the study With no history of facial skin care (peeling, mask…) 15 days before the beginning of the study and agreeing not to perform during the study Volunteers accepting not changing their local treatment on face Who agree to avoid UV exposure (sun or tanning booth) during the study Who have a fixed address and are entitled to Social Security or a similar National Insurance scheme Who sign a written informed consent Exclusion Criteria: Pregnant, nursing, or intending to become pregnant in the course of the study With a history of allergy or hypersensitivity to the products or one of their components Having use oral nutritional supplements and/or vitamin supplementation less than one month before and/or refusing not consuming nutritional supplement during the study Having used cosmetics and/or topical preparations containing ingredients claiming efficacy on skin radiance less than 15 days before and/or during the study With a dermatosis, systemic disease or treatment susceptible to interfere with the evolution of the parameters of the study or with taking the nutritional supplement Participation in another clinical trial evaluating skin radiance during the last month before the study Participation in another clinical trial or volunteers being in the exclusion phase of such a trial, thus being unable to participate in any other one Who have forfeited their freedom by judiciary decision or are deemed legally incompetent Having perceived more than 4500 € as indemnification fees for participation in clinical trials during the preceding 12 months (including participation in this clinical trial) Unable to comply with the protocol constraints Who cannot be contacted by phone rapidly

Ages Eligible for Study
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Minimum Age: 40 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: X34<br>Arm supplemented with X34 | Dietary Supplement: X34<br>* Dietary supplement named X34<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Skin radiance: clinical scoring |  | At 0 week and 8 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Subject self-assessments | Subjects will evaluate the radiance of their complexion by self-assessment. | At 0 week and 8 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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antioxidant, skin radiance, skin elasticity, skin firmness, skin hydration