Text Message Vaccine Reminders for Adolescents With Chronic Medical Conditions

Study Overview
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Brief Summary
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There are a growing number of adolescents with chronic medical conditions in the United States. The Advisory Committee on Immunization Practices (ACIP) recommends HPV vaccination and annual influenza vaccination of all adolescents. Pneumococcal polysaccharide vaccination is also recommended for certain high-risk patients. Limited studies suggest that vaccination coverage of this population remains sub-optimal. Text message vaccine reminder/recall has been shown to be effective in increasing uptake of select pediatric and adolescents vaccines, but has yet to be examined among patients with chronic medical conditions who may also face unique barriers to vaccination. This intervention aims to implement and evaluate the use of text message vaccine reminders among urban low-income minority adolescents with chronic medical conditions. This investigator-initiated study is supported in part by a grant from the Pfizer Medical Education Group.

Official Title
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Text Message Vaccine Reminders for Adolescents With Chronic Medical Conditions

Conditions
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Vaccination

Intervention / Treatment
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* Other: educational text message reminders
* Other: conventional text message reminders


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Parent with adolescent aged 11-17 years; adolescent with ≥1 chronic medical condition; adolescent with clinic visit in last 12 months; cell phone number listed in hospital registration system Exclusion Criteria: Parent who: does not speak English or Spanish; is unwilling to receive text message vaccine reminders; anticipates moving from area in coming 12 months

Ages Eligible for Study
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Minimum Age: 11 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: educational text message reminders<br>receipt of education-embedded text message vaccine reminders | Other: educational text message reminders<br> <br> * Other names: education-embedded text message vaccine reminders;|
| Active Comparator: conventional text message reminders<br>receipt of conventional text message vaccine reminders | Other: conventional text message reminders<br> <br> * Other names: conventional text message vaccine reminders;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Percentage of eligible subjects who received HPV1, influenza, and/or pneumococcal vaccine(s) |  | 12 weeks after intervention start | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Percentage of eligible subjects who received HPV1, influenza, and/or pneumococcal vaccine(s) |  | 4 weeks after intervention start | 
| Percentage of eligible subjects who received HPV1, influenza, and/or pneumococcal vaccine(s) |  | 24 weeks after intervention start | 
| Percentage of eligible subjects with missed opportunities for HPV1, influenza, and/or pneumococcal vaccination |  | 4 weeks after intervention start | 
| Percentage of eligible subjects with missed opportunities for HPV1, influenza, and/or pneumococcal vaccination |  | 12 weeks after intervention start | 
| Percentage of eligible subjects with missed opportunities for HPV1, influenza, and/or pneumococcal vaccination |  | 24 weeks after intervention start |