Subjective Outcomes After ACL Reconstruction With BQT Autograft

Study Overview
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Brief Summary
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The purpose of the study is to compare short-term patient reported outcome measures (PROM) of Bone-Quadriceps-Tendon (BQT) autograft with Semitendinosus-Gracilis (STG) and Bone-Patellar-Tendon-Bone (BPTB) autografts following Anterior Cruciate Ligament Reconstruction (ACLR). The PROM used are Knee Injury and Osteoarthrithis Outcome Score (KOOS) and Tegner. Difference in change in KOOS, KOOS subscales and Tegner from preoperative baseline to one-year follow-up and absolute KOOS, KOOS subscales and Tegner at one-year follow-up were evaluated. All of which were BQT compared to STG and BPTB, respectively. The primary outcome is change in KOOS from preoperative baselinge to one-year follow-up. Other outcomes are secondary. The hypothesis was that patients receiving the BQT autograft show similar results in KOOS, KOOS subscales and Tegner as patients receiving STG or BPTB autografts.

Official Title
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Subjective Outcomes After ACL Reconstruction With BQT Autograft

Conditions
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ACL Injury, Knee Injuries

Intervention / Treatment
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* Procedure: Graft type at ACLR


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: - Exclusion Criteria: Revision ACL Surgery Multiligament surgery Nonresponders in PROM at preoperative baseline or one-year follow-up
Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| BQT<br>Patients treated with the Bone Quadriceps Tendon (BQT) autograft | Procedure: Graft type at ACLR<br>* The choice of graft at primary ACL Reconstruction<br>|
| STG<br>Patients treated with the Semitendinosus-Gracilis (STG) autograft | Procedure: Graft type at ACLR<br>* The choice of graft at primary ACL Reconstruction<br>|
| BPTB<br>Patients treated with the Bone-Patellar Tendon-Bone (BPTB) autograft | Procedure: Graft type at ACLR<br>* The choice of graft at primary ACL Reconstruction<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Knee Injury and Osteoarthritis Outcome Score from preoperative baseline to one-year follow-up | BQT compared to STG and BPTB, respectively | 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Knee Injury and Osteoarthritis Outcome Score subscale Pain from preoperative baseline to one-year follow-up | BQT compared to STG and BPTB, respectively | 1 year | 
| Change in Knee Injury and Osteoarthritis Outcome Score subscale Symptoms from preoperative baseline to one-year follow-up | BQT compared to STG and BPTB, respectively | 1 year | 
| Change in Knee Injury and Osteoarthritis Outcome Score subscale Activities of Daily Living (ADL) from preoperative baseline to one-year follow-up | BQT compared to STG and BPTB, respectively | 1 year | 
| Change in Knee Injury and Osteoarthritis Outcome Score subscale Sports/Recreation from preoperative baseline to one-year follow-up | BQT compared to STG and BPTB, respectively | 1 year | 
| Change in Knee Injury and Osteoarthritis Outcome Score subscale Quality of Life (QoL) from preoperative baseline to one-year follow-up | BQT compared to STG and BPTB, respectively | 1 year | 
| Change in Tegner activity score from preoperative baseline to one-year follow-up | BQT compared to STG and BPTB, respectively | 1 year | 
| Absolute results of Knee Injury and Osteoarthritis Outcome Score subscale Pain at one-year follow-up | BQT compared to STG and BPTB, respectively | 1 year | 
| Absolute results of Knee Injury and Osteoarthritis Outcome Score subscale Symptoms at one-year follow-up | BQT compared to STG and BPTB, respectively | 1 year | 
| Absolute results of Knee Injury and Osteoarthritis Outcome Score subscale Activities of Daily Living (ADL) at one-year follow-up | BQT compared to STG and BPTB, respectively | 1 year | 
| Absolute results of Knee Injury and Osteoarthritis Outcome Score subscale Sports/Recreation at one-year follow-up | BQT compared to STG and BPTB, respectively | 1 year | 
| Absolute results of Knee Injury and Osteoarthritis Outcome Score subscale Quality of Life (QoL) at one-year follow-up | BQT compared to STG and BPTB, respectively | 1 year | 
| Absolute results of Tegner activity score at one-year follow-up | BQT compared to STG and BPTB, respectively | 1 year |