An Analysis Into the Cause and Preventional Method of Thromboembolic Disease in Gynecological Surgery

Study Overview
=================
Brief Summary
-----------------
The aim of this cross-sectional study is to describe the specific situations of thromboembolic disease in gynecological surgery and identify the risk factors of it.

Detailed Description
-----------------
The electronic medical data of 54 patients who undergo operations to treat gynecological diseases but develop thromboembolic disease will be analyzed retrospectively in this study. The location, symptom and other situations of embolism will be described and multiple linear analyse will be employed to identify the risk factors of it.

Official Title
-----------------
An Analysis Into the Cause and Preventional Method of Thromboembolic Disease in Gynecological Surgery

Conditions
-----------------
Thromboembolic Disease, Gynecological Surgery

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Volunteer to participate in the study with informed consent; Females aged 20-80 who are confirmed with some gynecological diseases and are treated with surgery but embolism happens unfortunately. Exclusion Criteria: Pregnancy, lactation, postmenopause, or planned pregnancy within two years; Patients with blood diseases prone to thrombosis and those with a history of thrombus were excluded; History of hyperparathyroidism, infectious diseases (tuberculosis, AIDS), autoimmune diseases, or digestive system diseases (malabsorption, crohn disease and dysentery); Other diseases or heavy injuries that will interfere with the results; Simultaneous participation in another clinical study with investigational medicinal product(s) or researcher thinks the subjects are not suitable for this trial.

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Thromboembolic Disease<br>the patients who undergo gynecological operations but develop thromboembolic disease | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the percentage of different symptoms of thromboembolic disease(%) | different patients will have various symptoms of embolism like dyspnea, chest pain, hemoptysis and syncope. And we plan to describe the distribution of it. | 10 months after the operation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the location of embolism | embolism can occur in different parts like the brain, limb, pulmonary and coronary systems. We plan to summarize the location of embolism. | 10 months after the operation | 
| the risk factors of thromboembolic disease | Performing multiple linear regression analysis with statistical product and service solutions(SPSS) 17.0, we plan to identify the risk factors which can increase the possibility of thromboembolic disease from possible factors like hypertension, diabetes, etc. | 10 months after the operation |