In-Hospital Hyperglycemia: Effects of Treatment on Glycemic Control and Clinical Outcome

Study Overview
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Brief Summary
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To improve glycemic control of inpatients admitted to the internal medicine wards, the researchers generated a protocol based on intensive insulin treatment for use in all inpatients with hyperglycemia. The researchers hypothesize that intensive insulin treatment will improve the glycemic control and the outcome of hospitalized patients. Study Information: All patients with a history of diabetes admitted to the internal medicine ward were enrolled in the study. At baseline, demographic and clinical information were obtained, including information necessary to determine the severity of the illness. Venous capillary blood glucose levels were checked 4 times a day by glucometer. During the pre-intervention period, patients were treated according to the common practice in the hospital without any intervention. The study team collected the baseline data on the glycemic control and treatment of patients admitted with hyperglycemia. During the intervention period, the study team visited the ward daily and guided the medical staff as to the use of the treatment protocol. During the post-intervention period, the study team collected the data without active intervention in the implementation of the protocol. Data was collected on the mode of treatment and glycemic control of all hyperglycemic patients throughout the study. The incidence of hypoglycemia, complications (myocardial infarction, stroke, infections), mortality, transfer to intensive care unit (ICU), length of hospitalization, and disposition at discharge were noted.

Official Title
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In-Hospital Hyperglycemia: Effects of Treatment on Glycemic Control and Clinical Outcome

Conditions
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Diabetes, Hyperglycemia

Intervention / Treatment
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* Behavioral: Implementation of a protocol for treatment of hyperglycemia


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All patients admitted to the internal medicine ward with hyperglycemia Exclusion Criteria: Patients admitted due to hypoglycemia, hyperosmolar state, and ketoacidosis
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: Implementation of a protocol for treatment of hyperglycemia|nan|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mean blood glucose during hospitalization |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Hypoglycemic events |  |  | 
| Length of in-hospital stay |  |  | 
| Infections |  |  | 
| Complications (myocardial infarction, stroke) |  |  | 
| Disposition at discharge (home, nursing home) |  |  | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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diabetes, hyperglycemia, hospital, medicine ward