Inter-Hospital Transfer to a Vascular Neurology Unit After Telethrombolysis

Study Overview
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Brief Summary
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Early thrombolysis is essential in treating ischemic strokes. The time window for thrombolysis is limited to 4,5 hours after symptoms onset. In the French region of Franche Comté, in order to reduce the thrombolytic delay, a telemedicine network was developed between the neurovascular reference unit (NVU) localised in the University Hospital of Besançon and the peripheral hospital centres. Patients may then be transported to the NVU immediately after the thrombolysis initiation. The aim of our study was to assess the relevance of a systematic medicalization of transfer to the NVU of patients with stroke who were telethrombolyzed before. It was a retrospective, monocentric and observational study conducted over 24 months, in Franche-Comte (France).

Detailed Description
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Stroke is a major health problem with increasing incidence. It represents the leading cause of disability and the third cause of death in France. There are two main types of stroke: ischemic (80%) or hemorrhagic (20%). Early thrombolysis is essential in treating ischemic strokes. The time window for thrombolysis is limited to 4,5 hours after symptoms onset. In the French region of Franche Comté, in order to reduce the thrombolytic delay, a telemedicine network was developed between the neurovascular reference unit (NVU) localised in the University Hospital of Besançon and the peripheral hospital centres. Patients may then be transported to the NVU immediately after the thrombolysis initiation. The aim of our study was to assess the relevance of a systematic medicalization of transfer to the NVU of patients with stroke who were telethrombolyzed before. It was a retrospective, monocentric and observational study conducted over 24 months, in Franche-Comte (France). Evaluation of neurological status was made with the Glasgow score (GCS) and National Institute of Health Stroke Score (NIHSS). The respiratory (SpO2; needs O2) and hemodynamic status (arterial blood pressure, heart rate) were assessed as well as the need for medical resuscitation at different times of the transport (thrombolysis, transfer, arrival at the Regional University Hospital Centre).

Official Title
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Inter-Hospital Transfer to a Vascular Neurology Unit After Telethrombolysis in France Comté

Conditions
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Ischemic Stroke

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patient with ischaemic stroke Emergency department admission between 01/01/2012 and 12/31/2013 Telemedicine stroke consult Thrombolysis therapy Patient transfered to NVU after thrombolysis initiation Transfer staffed by a qualified physician Exclusion Criteria: Transfer non staffed by a qualified physician

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Patient neurological status assessed by NIHSS score during transfer to NVU |  | one day | 
| Patient neurological status assessed by Glasgow score during transfer to NVU |  | one day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Patient respiratory status assessed by oxygen saturation |  | one day | 
| Patient hemodynamic status assessed by systolic and diastolic pressure |  | one day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Telemedecine, Thrombolysis