Postoperative Changes in Head and Neck Cancer Patients Undergoing Surgery

Study Overview
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Brief Summary
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The aim of this study is to evaluate the postoperative changes after a major surgery in head and neck cancer patients. Each participant will be evaluated three times: (1) One day before surgery; (2) one month postoperative and (3) three months postoperative. Assessments included blood pressure, anthropometric measurements, physical measurements and questionnaires on quality of life, nutritional status and cancer symptoms.

Official Title
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Postoperative Changes in Head and Neck Cancer Patients Undergoing Surgery

Conditions
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Head and Neck Cancer

Intervention / Treatment
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* Behavioral: Observational group


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Diagnosis of head and neck cancer patients planned for an elective major surgery More than 18 years of age Able to read, write and understand French Exclusion Criteria: - Neurological or orthopedic impairments not suitable for testing

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: Observational group|nan|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in functional exercise capacity | Functional exercise capacity is measured by a 6-minute walk test | Assessments one day before surgery, 1 and 3 months postoperative | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in muscle fatigability | Muscle fatigability is measured using a Cybex dynamometer | Assessments one day before surgery, 1 and 3 months postoperative | 
| Change in flexibility | Flexibility is measured by Toe touch test | Assessments one day before surgery, 1 and 3 months postoperative | 
| Change in flexibility | Flexibility is measured by sit and reach test | Assessments one day before surgery, 1 and 3 months postoperative | 
| Change in upper body strength and endurance | Upper body strength and endurance are measured by the 30-second arm curl test | Assessments one day before surgery, 1 and 3 months postoperative | 
| Change in hand grip strength | Hand grip strength test is performed using a Jamar® dynamometer | Assessments one day before surgery, 1 and 3 months postoperative | 
| Change in health-related quality of life | Health-related quality of life is evaluated with the version 4 of the University of Washington head and neck cancer questionnaire | Assessments one day before surgery, 1 and 3 months postoperative | 
| Change in common symptom batteries in cancer patients | Common symptom batteries is measured by the Edmonton Symptom Assessment System (revised version) questionnaire | Assessments one day before surgery, 1 and 3 months postoperative | 
| Change in nutritional status | Nutritional status is measured with the Short Nutritional Assessment Questionnaire | Assessments one day before surgery, 1 and 3 months postoperative | 
| Change in blood pressure | Resting blood pressure is measured using the M6 Comfort automatic blood pressure monitor | Assessments one day before surgery, 1 and 3 months postoperative | 
| Change in weight | Weight (kg) is measured by using a bioelectrical impedance analysis | Assessments one day before surgery, 1 and 3 months postoperative | 
| Change in fat body mass | Fat body mass (%) is measured by using a bioelectrical impedance analysis | Assessments one day before surgery, 1 and 3 months postoperative | 
| Change in waist circumference | Waist circumference is measured with a non-elastic tape measure | Assessments one day before surgery, 1 and 3 months postoperative |