Improvement of Intentional and Unintentional Non-adherence in the Elderly

Study Overview
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Brief Summary
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The purpose is to study if different factors influence medicine adherence in elderly people. In this study number of generic substitution and use of non-prescription drugs, herbal medicine and dietary supplement is in focus.

Detailed Description
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The purpose of this study is to describe in the elderly: Association between medicine adherence and number of generic substitution Association between medicine adherence and use of non-prescription drugs, herbal medicine and dietary supplements and interaction between 'prescription drugs' and 'non-prescription drugs, herbal medicine and dietary supplements' Intentional and unintentional non-adherence Some of the data in the present study were originally collected as part of a major research project 'Methods for Improving Compliance with Medicine Intake' (MICMI). The study sample of 945 persons was randomly selected into three groups: two intervention groups and one control group. Interventions were pharmaceutical care and an electronic reminder system. All groups were followed for one year. Data in the present study is from the pharmaceutical care group and the control group, and is descriptive.

Official Title
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Improvement of Intentional and Unintentional Non-adherence in the Elderly. Importance of Pharmaceutical Care, Generic Substitution, Non-prescription Drugs, Herbal Medicine and Dietary Supplements

Conditions
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Medication Adherence

Intervention / Treatment
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* Other: Pharmaceutical care


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Aged 65 years or older Living in their own homes Without assistance to medicine administration Living in the Municipality of Aarhus, Denmark Long-term treatment with > 4 prescription drugs Exclusion Criteria:

Ages Eligible for Study
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Minimum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Pharmaceutical care<br> | Other: Pharmaceutical care<br>* Information about medicine, sideeffect, adherence<br>* Other names: Pharmaceutical Services;|
| Control<br> | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Medicine adherence |  | One year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of generic substitution |  | One year | 
| Use of non-prescription drugs, herbal medicine and dietary supplements and frequency of interaction between 'prescription drugs' and 'non-prescription drugs, herbal medicine and dietary supplements' |  | Actually day | 
| Intentional and unintentional non-adherence association with generic substitution and use of non-prescription drugs, herbal medicine and dietary supplements |  | One year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Medicine adherence, Drug substitution, Herb-drug interaction, Herbal medicine, Dietary supplements, Over-the-counter products, On-line prescription records, Personal electronic medicine profile, Intentional non-adherence, Unintentional non-adherence