High vs Normal Protein Diets, Resistance Exercise, Lean Mass and Strength Gains

Study Overview
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Brief Summary
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This study evaluates the effect of different types of diets (high and normal protein) on lean and fat mass, and strength in postmenopausal women practitioners of resistance exercise. Two groups will be created: high protein (1.2 protein g/body mass/day) and normal protein (0.8 protein g/body mass/day). The same training will be performed for both groups.

Detailed Description
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Both groups will undergo the same training protocol, differing only on the protein content of the diet. The dietary assessment will be made through the 24-hour food recall, being conducted at the beginning, middle and end of the intervention. Resistance exercises for upper and lower limbs will be performed, at 70% of one repetition maximum. SPPB, tug, 6-minutes and 400 meters will be performed.

Official Title
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Effect of Normal and High Protein Diets in Lean Mass, Adiposity, and Strength in Postmenopausal Women Practitioners of Resistance Exercise

Conditions
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Sarcopenia

Intervention / Treatment
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* Other: High protein
* Other: Normal protein
* Other: Training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Women in the postmenopausal period (menopausal for at least one year, confirmed by laboratory diagnostic tests menopause - LH and high FSH and estradiol decreased); Healthy; Who agree to participate and sign the consent term. Exclusion Criteria: The one who does not provide the necessary information for the development of the study; Present orthopedic limitations; Patients with previously diagnosed and treatment of diseases such as type II diabetes mellitus, hypertension and cardiovascular disease.
Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: High protein diet (HP)<br>Diet with 1.2 protein g/kg body mass/day for postmenopausal women practitioners of resistance exercise. The physical strength training will be performed equally by both groups | Other: High protein<br>* To observe the effect of a high protein (HP) diet over muscle mass, fat mass, and strength changes, focusing in differences between the NP and HP groups.<br>Other: Training<br>* The physical strength training will be performed equally by both groups, containing exercises for upper and lower limbs and aiming for hypertrophy.<br>|
| Placebo Comparator: Normal protein diet (NP)<br>Diet with 0.8 protein g/kg body mass/day for postmenopausal women practitioners of resistance exercise. The physical strength training will be performed equally by both groups | Other: Normal protein<br>* To observe the effect of a normal protein (NP) diet over muscle mass, fat mass, and strength changes<br>Other: Training<br>* The physical strength training will be performed equally by both groups, containing exercises for upper and lower limbs and aiming for hypertrophy.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes in the lean mass of postmenopausal women practicing strength exercise |  | Before and immediately after the intervention (initial moment and 10 weeks after start of the intervention) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes in the fat mass of postmenopausal women practicing strength exercise |  | Before and immediately after the intervention (initial moment and 10 weeks after start of the intervention) | 
| Changes on strength of postmenopausal women practicing strength exercise |  | Before and immediately after the intervention (initial moment and 10 weeks after start of the intervention) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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lean mass, postmenopausal, protein