Extended Application of Intraoperative Parathyroid Scores System(IPSS) in Thyroidectomy

Study Overview
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Brief Summary
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after established the Intraoperative Parathyroid Scores System (IPSS) for thyroidectomy we further extented the clinical value of Intraoperative Parathyroid Scores System in Treatment decisions of calcium treatment time and improve recognition skills of parathyroid in Clinicians

Detailed Description
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IPSS includes transplantation Parathyroid Scores and in situ Parathyroid Scores, the investigators will establish the Intraoperative Parathyroid Scores System by parathyroid size and Blood supply, and recording IPSS, according to certain rules. We expand IPSS, including the description of the location of parathyroid after postoperative.Parathyroid hormone and calcium were test in d0, d1, d14, d60 post operation. The correlation between Intraoperative Parathyroid Scores and PTH calcium were calculated, and ROC curve and logistic regression were tested for the prediction value.and after that we further evaluate the relationship Between IPSS and calcium supplement time.and Whether IPSS enhance ability of parathyroid recognition for clinical doctors.

Official Title
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Extended Application of Intraoperative Parathyroid Scores System(IPSS) in Thyroidectomy

Conditions
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Intraoperative Parathyroid Scores System

Intervention / Treatment
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* Behavioral: with IPSS


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: postoperative pathology confirmed as thyroid papillary carcinoma; for the first time to undergo thyroid surgery, no history of neck surgery and external radiotherapy; preoperative serum calcium, parathyroid hormone levels were normal; intraoperative and postoperative clinical data integrity, standardized follow-up patients; parathyroid is a tumor violation. Exclusion Criteria: serious underlying disease; age greater than 60 years of age or combined with arteriosclerotic disease; patients with postoperative loss; patients with parathyroid disease.

Ages Eligible for Study
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Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| with IPSS record/IPSS<br>the surgoen use the IPSS in all thyroidectomy | Behavioral: with IPSS<br>* all patient in one group use IPSS to record the parathyroid status. the other group operation as ordinary. record the parathyroid status in verbal description<br>|
| Traditionaldescription Group/TD<br>the surgoen without the IPSS，use Traditional description | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Differences of parathyroid records between IPSS and TD | The percentage of recorded integrity of the parathyroid gland and the number of recognizable parathyroids were compared between the two groups. | 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The effect of IPSS on the level of parathyroid recognition of surgeons | Comparison of the number of parathyroid gland found in the pathology and the number of postoperative hypoparathyroidism between the two groups | 1 year | 
| differences of the number of parathyroid glands found in the pathology betwen IPSS and TD | differences of the number of parathyroid glands found in the pathology betwen IPSS and TD | 1 year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Intraoperative Parathyroid Scores System, total thyroidectomy, thyroid cancer, hypoparathyroidism, prediction