Role of Depression in Blood Pressure Control. Study

Study Overview
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Brief Summary
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Our study aims to evaluate the role of depression in blood pressure control in ambulatory hypertensive patients.

Detailed Description
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Research Problem: Hypertension is a multifactorial disease that affects approximately one quarter of the adult population. It is a major risk factor for stroke and cardiovascular disease. Environmental and psychosocial factors play an important role in hypertension onset and control. The prevalence of depression among hypertensive patients is 26, 8% and its presence is associated with increased risk of cardiovascular-related morbi-mortality. Our study aims to evaluate the role of depression in blood pressure control in ambulatory hypertensive patients. Investigative process: This study is a cross-sectional, multicentric and descriptive study. the investigators intend to include three hundred and two patients. After obtaining their consent, a 24 hour ambulatory blood pressure monitor will be used to evaluate blood pressure control. Depression was assessed by the 9-item-Patient Health Questionnaire (PHQ-9) in Tunisian dialect. Clinical, socio-environmental, psychosocial and therapeutic and prognosis data will be collected from medical records.

Official Title
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Role of Depression in Blood Pressure Control. A Cross-sectional Multicentric Study

Conditions
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Hypertension, Depression

Intervention / Treatment
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* Diagnostic Test: Blood Pressure Monitoring, Ambulatory


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients consulting for high blood pressure Patients older than 18 years. Patients able to give informed consent. Non inclusion Criteria : Patients followed for depression under treatment. Hospitalized patients Exclusion Criteria: a white coat hypertension

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 100 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Ambulatory patients<br>Patient with a high blood pressure during regular visit will undertake an ambulatory blood pressure monitoring. Before wearing the device , they will be asked to answer to the questionnaire and the investigators will gather their demographic,clinical characteristics and dietary habits data. Ethical considerations will be undertaken and respected. | Diagnostic Test: Blood Pressure Monitoring, Ambulatory<br>* To monitor the blood pressure during 24 hours.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| prevalence of depression in uncontrolled hypertensive patients. | The prevalence of depression evaluated by PHQ9 in Tunisian dialect in hypertensive patients with abnormal ambulatory 24 hours blood pressure monitoring | on inclusion | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Patient Health Questionnaire, Blood Pressure Monitoring, Ambulatory, hypertension, depression