Evaluation of OxxyneaGS in Acute Glycemic Regulation on Light Hyperglycemic Subjects

Study Overview
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Brief Summary
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This study aims to evaluate and select the best combination of polyphenol and white kidney bean ingredients in the acute glycemic modulation after a complete meal by measuring blood glucose and insulin.

Official Title
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OxxyneaGS: Single Blinded Randomized Study

Conditions
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Hyperglycemia, Postprandial

Intervention / Treatment
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* Dietary Supplement: Verum T1
* Dietary Supplement: Verum T2
* Dietary Supplement: Verum T3
* Dietary Supplement: Verum T4
* Dietary Supplement: Verum T5
* Dietary Supplement: Verum T6
* Dietary Supplement: Verum T7
* Dietary Supplement: Verum T8
* Dietary Supplement: Verum T9
* Dietary Supplement: Verum T10
* Dietary Supplement: Verum T11
* Dietary Supplement: Verum T12
* Dietary Supplement: Verum T13
* Dietary Supplement: Verum T14
* Dietary Supplement: Verum T15
* Dietary Supplement: Verum T16
* Dietary Supplement: Verum T17


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Glycemia: 100-125mg/dL Both sexes Overweight BMI range (27-32) Age: 20-50 years old Exclusion Criteria: Metabolic/Chronical disease Menopausal women Being pregnant, breastfeeding or wanting to have a baby Former obese with a history of yoyo effect Have been involved in a weight loss program in the past 12 months or subjected to weight reduction surgery Having started or quit smoking, having a high alcohol consumption Have in the past been in a long-term antibiotherapy (1 month or more) and/or a regular antibiotherapy in the past 12 months Allergy to olive, artichoke, black currant, grapefruit, grape, white kidney bean, olive, pomegranate.

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
-----------------

Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Placebo Comparator: Verum T1<br> | Dietary Supplement: Verum T1<br>* Verum T1 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T2<br>* Verum T2 is a 11500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T3<br>* Verum T3 is a 11500AAIU/g white kidney bean extract. Daily dosage is 565 mg in 3 capsules<br>Dietary Supplement: Verum T4<br>* Verum T4 is a 17500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T5<br>* Verum T5 is a 17500AAIU/g white kidney bean extract. Daily dosage is 371 mg in 3 capsules<br>Dietary Supplement: Verum T6<br>* Verum T6 is a 34200AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T7<br>* Verum T4 is a 34200AAIU/g white kidney bean extract. Daily dosage is 512 mg in 3 capsules<br>Dietary Supplement: Verum T8<br>* Verum T8 is a 34200AAIU/g white kidney bean extract. Daily dosage is 190 mg in 3 capsules.<br>Dietary Supplement: Verum T9<br>* Verum T9 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T10<br>* Verum T10 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 500 mg in 3 capsules<br>Dietary Supplement: Verum T11<br>* Verum T11 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 900 mg in 3 capsules<br>Dietary Supplement: Verum T12<br>* Verum T12 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 600 mg in 3 capsules<br>Dietary Supplement: Verum T13<br>* Verum T13 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T14<br>* Verum T14 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 900 mg in 3 capsules.<br>Dietary Supplement: Verum T15<br>* Verum T15 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, Zinc, and, black currant leaf extracts. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T16<br>* Verum T16 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, and Zinc. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T17<br>* Verum T17 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>|
| Experimental: Verum T2<br> | Dietary Supplement: Verum T1<br>* Verum T1 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T2<br>* Verum T2 is a 11500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T3<br>* Verum T3 is a 11500AAIU/g white kidney bean extract. Daily dosage is 565 mg in 3 capsules<br>Dietary Supplement: Verum T4<br>* Verum T4 is a 17500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T5<br>* Verum T5 is a 17500AAIU/g white kidney bean extract. Daily dosage is 371 mg in 3 capsules<br>Dietary Supplement: Verum T6<br>* Verum T6 is a 34200AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T7<br>* Verum T4 is a 34200AAIU/g white kidney bean extract. Daily dosage is 512 mg in 3 capsules<br>Dietary Supplement: Verum T8<br>* Verum T8 is a 34200AAIU/g white kidney bean extract. Daily dosage is 190 mg in 3 capsules.<br>Dietary Supplement: Verum T9<br>* Verum T9 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T10<br>* Verum T10 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 500 mg in 3 capsules<br>Dietary Supplement: Verum T11<br>* Verum T11 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 900 mg in 3 capsules<br>Dietary Supplement: Verum T12<br>* Verum T12 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 600 mg in 3 capsules<br>Dietary Supplement: Verum T13<br>* Verum T13 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T14<br>* Verum T14 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 900 mg in 3 capsules.<br>Dietary Supplement: Verum T15<br>* Verum T15 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, Zinc, and, black currant leaf extracts. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T16<br>* Verum T16 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, and Zinc. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T17<br>* Verum T17 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>|
| Experimental: Verum T3<br> | Dietary Supplement: Verum T1<br>* Verum T1 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T2<br>* Verum T2 is a 11500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T3<br>* Verum T3 is a 11500AAIU/g white kidney bean extract. Daily dosage is 565 mg in 3 capsules<br>Dietary Supplement: Verum T4<br>* Verum T4 is a 17500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T5<br>* Verum T5 is a 17500AAIU/g white kidney bean extract. Daily dosage is 371 mg in 3 capsules<br>Dietary Supplement: Verum T6<br>* Verum T6 is a 34200AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T7<br>* Verum T4 is a 34200AAIU/g white kidney bean extract. Daily dosage is 512 mg in 3 capsules<br>Dietary Supplement: Verum T8<br>* Verum T8 is a 34200AAIU/g white kidney bean extract. Daily dosage is 190 mg in 3 capsules.<br>Dietary Supplement: Verum T9<br>* Verum T9 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T10<br>* Verum T10 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 500 mg in 3 capsules<br>Dietary Supplement: Verum T11<br>* Verum T11 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 900 mg in 3 capsules<br>Dietary Supplement: Verum T12<br>* Verum T12 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 600 mg in 3 capsules<br>Dietary Supplement: Verum T13<br>* Verum T13 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T14<br>* Verum T14 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 900 mg in 3 capsules.<br>Dietary Supplement: Verum T15<br>* Verum T15 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, Zinc, and, black currant leaf extracts. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T16<br>* Verum T16 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, and Zinc. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T17<br>* Verum T17 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>|
| Experimental: Verum T4<br> | Dietary Supplement: Verum T1<br>* Verum T1 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T2<br>* Verum T2 is a 11500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T3<br>* Verum T3 is a 11500AAIU/g white kidney bean extract. Daily dosage is 565 mg in 3 capsules<br>Dietary Supplement: Verum T4<br>* Verum T4 is a 17500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T5<br>* Verum T5 is a 17500AAIU/g white kidney bean extract. Daily dosage is 371 mg in 3 capsules<br>Dietary Supplement: Verum T6<br>* Verum T6 is a 34200AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T7<br>* Verum T4 is a 34200AAIU/g white kidney bean extract. Daily dosage is 512 mg in 3 capsules<br>Dietary Supplement: Verum T8<br>* Verum T8 is a 34200AAIU/g white kidney bean extract. Daily dosage is 190 mg in 3 capsules.<br>Dietary Supplement: Verum T9<br>* Verum T9 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T10<br>* Verum T10 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 500 mg in 3 capsules<br>Dietary Supplement: Verum T11<br>* Verum T11 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 900 mg in 3 capsules<br>Dietary Supplement: Verum T12<br>* Verum T12 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 600 mg in 3 capsules<br>Dietary Supplement: Verum T13<br>* Verum T13 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T14<br>* Verum T14 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 900 mg in 3 capsules.<br>Dietary Supplement: Verum T15<br>* Verum T15 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, Zinc, and, black currant leaf extracts. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T16<br>* Verum T16 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, and Zinc. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T17<br>* Verum T17 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>|
| Experimental: Verum T5<br> | Dietary Supplement: Verum T1<br>* Verum T1 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T2<br>* Verum T2 is a 11500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T3<br>* Verum T3 is a 11500AAIU/g white kidney bean extract. Daily dosage is 565 mg in 3 capsules<br>Dietary Supplement: Verum T4<br>* Verum T4 is a 17500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T5<br>* Verum T5 is a 17500AAIU/g white kidney bean extract. Daily dosage is 371 mg in 3 capsules<br>Dietary Supplement: Verum T6<br>* Verum T6 is a 34200AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T7<br>* Verum T4 is a 34200AAIU/g white kidney bean extract. Daily dosage is 512 mg in 3 capsules<br>Dietary Supplement: Verum T8<br>* Verum T8 is a 34200AAIU/g white kidney bean extract. Daily dosage is 190 mg in 3 capsules.<br>Dietary Supplement: Verum T9<br>* Verum T9 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T10<br>* Verum T10 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 500 mg in 3 capsules<br>Dietary Supplement: Verum T11<br>* Verum T11 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 900 mg in 3 capsules<br>Dietary Supplement: Verum T12<br>* Verum T12 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 600 mg in 3 capsules<br>Dietary Supplement: Verum T13<br>* Verum T13 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T14<br>* Verum T14 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 900 mg in 3 capsules.<br>Dietary Supplement: Verum T15<br>* Verum T15 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, Zinc, and, black currant leaf extracts. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T16<br>* Verum T16 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, and Zinc. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T17<br>* Verum T17 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>|
| Experimental: Verum T6<br> | Dietary Supplement: Verum T1<br>* Verum T1 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T2<br>* Verum T2 is a 11500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T3<br>* Verum T3 is a 11500AAIU/g white kidney bean extract. Daily dosage is 565 mg in 3 capsules<br>Dietary Supplement: Verum T4<br>* Verum T4 is a 17500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T5<br>* Verum T5 is a 17500AAIU/g white kidney bean extract. Daily dosage is 371 mg in 3 capsules<br>Dietary Supplement: Verum T6<br>* Verum T6 is a 34200AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T7<br>* Verum T4 is a 34200AAIU/g white kidney bean extract. Daily dosage is 512 mg in 3 capsules<br>Dietary Supplement: Verum T8<br>* Verum T8 is a 34200AAIU/g white kidney bean extract. Daily dosage is 190 mg in 3 capsules.<br>Dietary Supplement: Verum T9<br>* Verum T9 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T10<br>* Verum T10 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 500 mg in 3 capsules<br>Dietary Supplement: Verum T11<br>* Verum T11 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 900 mg in 3 capsules<br>Dietary Supplement: Verum T12<br>* Verum T12 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 600 mg in 3 capsules<br>Dietary Supplement: Verum T13<br>* Verum T13 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T14<br>* Verum T14 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 900 mg in 3 capsules.<br>Dietary Supplement: Verum T15<br>* Verum T15 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, Zinc, and, black currant leaf extracts. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T16<br>* Verum T16 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, and Zinc. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T17<br>* Verum T17 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>|
| Experimental: Verum T7<br> | Dietary Supplement: Verum T1<br>* Verum T1 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T2<br>* Verum T2 is a 11500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T3<br>* Verum T3 is a 11500AAIU/g white kidney bean extract. Daily dosage is 565 mg in 3 capsules<br>Dietary Supplement: Verum T4<br>* Verum T4 is a 17500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T5<br>* Verum T5 is a 17500AAIU/g white kidney bean extract. Daily dosage is 371 mg in 3 capsules<br>Dietary Supplement: Verum T6<br>* Verum T6 is a 34200AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T7<br>* Verum T4 is a 34200AAIU/g white kidney bean extract. Daily dosage is 512 mg in 3 capsules<br>Dietary Supplement: Verum T8<br>* Verum T8 is a 34200AAIU/g white kidney bean extract. Daily dosage is 190 mg in 3 capsules.<br>Dietary Supplement: Verum T9<br>* Verum T9 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T10<br>* Verum T10 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 500 mg in 3 capsules<br>Dietary Supplement: Verum T11<br>* Verum T11 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 900 mg in 3 capsules<br>Dietary Supplement: Verum T12<br>* Verum T12 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 600 mg in 3 capsules<br>Dietary Supplement: Verum T13<br>* Verum T13 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T14<br>* Verum T14 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 900 mg in 3 capsules.<br>Dietary Supplement: Verum T15<br>* Verum T15 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, Zinc, and, black currant leaf extracts. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T16<br>* Verum T16 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, and Zinc. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T17<br>* Verum T17 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>|
| Experimental: Verum T8<br> | Dietary Supplement: Verum T1<br>* Verum T1 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T2<br>* Verum T2 is a 11500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T3<br>* Verum T3 is a 11500AAIU/g white kidney bean extract. Daily dosage is 565 mg in 3 capsules<br>Dietary Supplement: Verum T4<br>* Verum T4 is a 17500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T5<br>* Verum T5 is a 17500AAIU/g white kidney bean extract. Daily dosage is 371 mg in 3 capsules<br>Dietary Supplement: Verum T6<br>* Verum T6 is a 34200AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T7<br>* Verum T4 is a 34200AAIU/g white kidney bean extract. Daily dosage is 512 mg in 3 capsules<br>Dietary Supplement: Verum T8<br>* Verum T8 is a 34200AAIU/g white kidney bean extract. Daily dosage is 190 mg in 3 capsules.<br>Dietary Supplement: Verum T9<br>* Verum T9 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T10<br>* Verum T10 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 500 mg in 3 capsules<br>Dietary Supplement: Verum T11<br>* Verum T11 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 900 mg in 3 capsules<br>Dietary Supplement: Verum T12<br>* Verum T12 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 600 mg in 3 capsules<br>Dietary Supplement: Verum T13<br>* Verum T13 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T14<br>* Verum T14 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 900 mg in 3 capsules.<br>Dietary Supplement: Verum T15<br>* Verum T15 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, Zinc, and, black currant leaf extracts. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T16<br>* Verum T16 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, and Zinc. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T17<br>* Verum T17 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>|
| Experimental: Verum T9<br> | Dietary Supplement: Verum T1<br>* Verum T1 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T2<br>* Verum T2 is a 11500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T3<br>* Verum T3 is a 11500AAIU/g white kidney bean extract. Daily dosage is 565 mg in 3 capsules<br>Dietary Supplement: Verum T4<br>* Verum T4 is a 17500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T5<br>* Verum T5 is a 17500AAIU/g white kidney bean extract. Daily dosage is 371 mg in 3 capsules<br>Dietary Supplement: Verum T6<br>* Verum T6 is a 34200AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T7<br>* Verum T4 is a 34200AAIU/g white kidney bean extract. Daily dosage is 512 mg in 3 capsules<br>Dietary Supplement: Verum T8<br>* Verum T8 is a 34200AAIU/g white kidney bean extract. Daily dosage is 190 mg in 3 capsules.<br>Dietary Supplement: Verum T9<br>* Verum T9 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T10<br>* Verum T10 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 500 mg in 3 capsules<br>Dietary Supplement: Verum T11<br>* Verum T11 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 900 mg in 3 capsules<br>Dietary Supplement: Verum T12<br>* Verum T12 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 600 mg in 3 capsules<br>Dietary Supplement: Verum T13<br>* Verum T13 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T14<br>* Verum T14 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 900 mg in 3 capsules.<br>Dietary Supplement: Verum T15<br>* Verum T15 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, Zinc, and, black currant leaf extracts. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T16<br>* Verum T16 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, and Zinc. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T17<br>* Verum T17 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>|
| Experimental: Verum T10<br> | Dietary Supplement: Verum T1<br>* Verum T1 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T2<br>* Verum T2 is a 11500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T3<br>* Verum T3 is a 11500AAIU/g white kidney bean extract. Daily dosage is 565 mg in 3 capsules<br>Dietary Supplement: Verum T4<br>* Verum T4 is a 17500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T5<br>* Verum T5 is a 17500AAIU/g white kidney bean extract. Daily dosage is 371 mg in 3 capsules<br>Dietary Supplement: Verum T6<br>* Verum T6 is a 34200AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T7<br>* Verum T4 is a 34200AAIU/g white kidney bean extract. Daily dosage is 512 mg in 3 capsules<br>Dietary Supplement: Verum T8<br>* Verum T8 is a 34200AAIU/g white kidney bean extract. Daily dosage is 190 mg in 3 capsules.<br>Dietary Supplement: Verum T9<br>* Verum T9 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T10<br>* Verum T10 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 500 mg in 3 capsules<br>Dietary Supplement: Verum T11<br>* Verum T11 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 900 mg in 3 capsules<br>Dietary Supplement: Verum T12<br>* Verum T12 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 600 mg in 3 capsules<br>Dietary Supplement: Verum T13<br>* Verum T13 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T14<br>* Verum T14 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 900 mg in 3 capsules.<br>Dietary Supplement: Verum T15<br>* Verum T15 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, Zinc, and, black currant leaf extracts. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T16<br>* Verum T16 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, and Zinc. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T17<br>* Verum T17 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>|
| Experimental: Verum T11<br> | Dietary Supplement: Verum T1<br>* Verum T1 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T2<br>* Verum T2 is a 11500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T3<br>* Verum T3 is a 11500AAIU/g white kidney bean extract. Daily dosage is 565 mg in 3 capsules<br>Dietary Supplement: Verum T4<br>* Verum T4 is a 17500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T5<br>* Verum T5 is a 17500AAIU/g white kidney bean extract. Daily dosage is 371 mg in 3 capsules<br>Dietary Supplement: Verum T6<br>* Verum T6 is a 34200AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T7<br>* Verum T4 is a 34200AAIU/g white kidney bean extract. Daily dosage is 512 mg in 3 capsules<br>Dietary Supplement: Verum T8<br>* Verum T8 is a 34200AAIU/g white kidney bean extract. Daily dosage is 190 mg in 3 capsules.<br>Dietary Supplement: Verum T9<br>* Verum T9 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T10<br>* Verum T10 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 500 mg in 3 capsules<br>Dietary Supplement: Verum T11<br>* Verum T11 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 900 mg in 3 capsules<br>Dietary Supplement: Verum T12<br>* Verum T12 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 600 mg in 3 capsules<br>Dietary Supplement: Verum T13<br>* Verum T13 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T14<br>* Verum T14 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 900 mg in 3 capsules.<br>Dietary Supplement: Verum T15<br>* Verum T15 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, Zinc, and, black currant leaf extracts. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T16<br>* Verum T16 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, and Zinc. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T17<br>* Verum T17 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>|
| Experimental: Verum T12<br> | Dietary Supplement: Verum T1<br>* Verum T1 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T2<br>* Verum T2 is a 11500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T3<br>* Verum T3 is a 11500AAIU/g white kidney bean extract. Daily dosage is 565 mg in 3 capsules<br>Dietary Supplement: Verum T4<br>* Verum T4 is a 17500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T5<br>* Verum T5 is a 17500AAIU/g white kidney bean extract. Daily dosage is 371 mg in 3 capsules<br>Dietary Supplement: Verum T6<br>* Verum T6 is a 34200AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T7<br>* Verum T4 is a 34200AAIU/g white kidney bean extract. Daily dosage is 512 mg in 3 capsules<br>Dietary Supplement: Verum T8<br>* Verum T8 is a 34200AAIU/g white kidney bean extract. Daily dosage is 190 mg in 3 capsules.<br>Dietary Supplement: Verum T9<br>* Verum T9 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T10<br>* Verum T10 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 500 mg in 3 capsules<br>Dietary Supplement: Verum T11<br>* Verum T11 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 900 mg in 3 capsules<br>Dietary Supplement: Verum T12<br>* Verum T12 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 600 mg in 3 capsules<br>Dietary Supplement: Verum T13<br>* Verum T13 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T14<br>* Verum T14 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 900 mg in 3 capsules.<br>Dietary Supplement: Verum T15<br>* Verum T15 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, Zinc, and, black currant leaf extracts. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T16<br>* Verum T16 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, and Zinc. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T17<br>* Verum T17 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>|
| Experimental: Verum T13<br> | Dietary Supplement: Verum T1<br>* Verum T1 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T2<br>* Verum T2 is a 11500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T3<br>* Verum T3 is a 11500AAIU/g white kidney bean extract. Daily dosage is 565 mg in 3 capsules<br>Dietary Supplement: Verum T4<br>* Verum T4 is a 17500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T5<br>* Verum T5 is a 17500AAIU/g white kidney bean extract. Daily dosage is 371 mg in 3 capsules<br>Dietary Supplement: Verum T6<br>* Verum T6 is a 34200AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T7<br>* Verum T4 is a 34200AAIU/g white kidney bean extract. Daily dosage is 512 mg in 3 capsules<br>Dietary Supplement: Verum T8<br>* Verum T8 is a 34200AAIU/g white kidney bean extract. Daily dosage is 190 mg in 3 capsules.<br>Dietary Supplement: Verum T9<br>* Verum T9 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T10<br>* Verum T10 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 500 mg in 3 capsules<br>Dietary Supplement: Verum T11<br>* Verum T11 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 900 mg in 3 capsules<br>Dietary Supplement: Verum T12<br>* Verum T12 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 600 mg in 3 capsules<br>Dietary Supplement: Verum T13<br>* Verum T13 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T14<br>* Verum T14 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 900 mg in 3 capsules.<br>Dietary Supplement: Verum T15<br>* Verum T15 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, Zinc, and, black currant leaf extracts. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T16<br>* Verum T16 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, and Zinc. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T17<br>* Verum T17 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>|
| Experimental: Verum T14<br> | Dietary Supplement: Verum T1<br>* Verum T1 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T2<br>* Verum T2 is a 11500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T3<br>* Verum T3 is a 11500AAIU/g white kidney bean extract. Daily dosage is 565 mg in 3 capsules<br>Dietary Supplement: Verum T4<br>* Verum T4 is a 17500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T5<br>* Verum T5 is a 17500AAIU/g white kidney bean extract. Daily dosage is 371 mg in 3 capsules<br>Dietary Supplement: Verum T6<br>* Verum T6 is a 34200AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T7<br>* Verum T4 is a 34200AAIU/g white kidney bean extract. Daily dosage is 512 mg in 3 capsules<br>Dietary Supplement: Verum T8<br>* Verum T8 is a 34200AAIU/g white kidney bean extract. Daily dosage is 190 mg in 3 capsules.<br>Dietary Supplement: Verum T9<br>* Verum T9 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T10<br>* Verum T10 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 500 mg in 3 capsules<br>Dietary Supplement: Verum T11<br>* Verum T11 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 900 mg in 3 capsules<br>Dietary Supplement: Verum T12<br>* Verum T12 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 600 mg in 3 capsules<br>Dietary Supplement: Verum T13<br>* Verum T13 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T14<br>* Verum T14 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 900 mg in 3 capsules.<br>Dietary Supplement: Verum T15<br>* Verum T15 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, Zinc, and, black currant leaf extracts. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T16<br>* Verum T16 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, and Zinc. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T17<br>* Verum T17 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>|
| Experimental: Verum T15<br> | Dietary Supplement: Verum T1<br>* Verum T1 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T2<br>* Verum T2 is a 11500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T3<br>* Verum T3 is a 11500AAIU/g white kidney bean extract. Daily dosage is 565 mg in 3 capsules<br>Dietary Supplement: Verum T4<br>* Verum T4 is a 17500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T5<br>* Verum T5 is a 17500AAIU/g white kidney bean extract. Daily dosage is 371 mg in 3 capsules<br>Dietary Supplement: Verum T6<br>* Verum T6 is a 34200AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T7<br>* Verum T4 is a 34200AAIU/g white kidney bean extract. Daily dosage is 512 mg in 3 capsules<br>Dietary Supplement: Verum T8<br>* Verum T8 is a 34200AAIU/g white kidney bean extract. Daily dosage is 190 mg in 3 capsules.<br>Dietary Supplement: Verum T9<br>* Verum T9 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T10<br>* Verum T10 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 500 mg in 3 capsules<br>Dietary Supplement: Verum T11<br>* Verum T11 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 900 mg in 3 capsules<br>Dietary Supplement: Verum T12<br>* Verum T12 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 600 mg in 3 capsules<br>Dietary Supplement: Verum T13<br>* Verum T13 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T14<br>* Verum T14 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 900 mg in 3 capsules.<br>Dietary Supplement: Verum T15<br>* Verum T15 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, Zinc, and, black currant leaf extracts. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T16<br>* Verum T16 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, and Zinc. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T17<br>* Verum T17 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>|
| Experimental: Verum T16<br> | Dietary Supplement: Verum T1<br>* Verum T1 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T2<br>* Verum T2 is a 11500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T3<br>* Verum T3 is a 11500AAIU/g white kidney bean extract. Daily dosage is 565 mg in 3 capsules<br>Dietary Supplement: Verum T4<br>* Verum T4 is a 17500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T5<br>* Verum T5 is a 17500AAIU/g white kidney bean extract. Daily dosage is 371 mg in 3 capsules<br>Dietary Supplement: Verum T6<br>* Verum T6 is a 34200AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T7<br>* Verum T4 is a 34200AAIU/g white kidney bean extract. Daily dosage is 512 mg in 3 capsules<br>Dietary Supplement: Verum T8<br>* Verum T8 is a 34200AAIU/g white kidney bean extract. Daily dosage is 190 mg in 3 capsules.<br>Dietary Supplement: Verum T9<br>* Verum T9 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T10<br>* Verum T10 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 500 mg in 3 capsules<br>Dietary Supplement: Verum T11<br>* Verum T11 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 900 mg in 3 capsules<br>Dietary Supplement: Verum T12<br>* Verum T12 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 600 mg in 3 capsules<br>Dietary Supplement: Verum T13<br>* Verum T13 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T14<br>* Verum T14 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 900 mg in 3 capsules.<br>Dietary Supplement: Verum T15<br>* Verum T15 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, Zinc, and, black currant leaf extracts. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T16<br>* Verum T16 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, and Zinc. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T17<br>* Verum T17 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>|
| Placebo Comparator: Verum T17<br> | Dietary Supplement: Verum T1<br>* Verum T1 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T2<br>* Verum T2 is a 11500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T3<br>* Verum T3 is a 11500AAIU/g white kidney bean extract. Daily dosage is 565 mg in 3 capsules<br>Dietary Supplement: Verum T4<br>* Verum T4 is a 17500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T5<br>* Verum T5 is a 17500AAIU/g white kidney bean extract. Daily dosage is 371 mg in 3 capsules<br>Dietary Supplement: Verum T6<br>* Verum T6 is a 34200AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T7<br>* Verum T4 is a 34200AAIU/g white kidney bean extract. Daily dosage is 512 mg in 3 capsules<br>Dietary Supplement: Verum T8<br>* Verum T8 is a 34200AAIU/g white kidney bean extract. Daily dosage is 190 mg in 3 capsules.<br>Dietary Supplement: Verum T9<br>* Verum T9 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 1000 mg in 3 capsules<br>Dietary Supplement: Verum T10<br>* Verum T10 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 500 mg in 3 capsules<br>Dietary Supplement: Verum T11<br>* Verum T11 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 900 mg in 3 capsules<br>Dietary Supplement: Verum T12<br>* Verum T12 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 600 mg in 3 capsules<br>Dietary Supplement: Verum T13<br>* Verum T13 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T14<br>* Verum T14 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 900 mg in 3 capsules.<br>Dietary Supplement: Verum T15<br>* Verum T15 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, Zinc, and, black currant leaf extracts. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T16<br>* Verum T16 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, and Zinc. Daily dosage is 1000 mg in 3 capsules.<br>Dietary Supplement: Verum T17<br>* Verum T17 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Acute change in glycemia in response to a meal, by measuring glucose concentration in the blood at different time points |  | 8 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Lipid profile evolution after a meal |  | 8 hours | 
| Oxxidative stress variation after a meal, measured by oxidized/reduced glutathione (GSH/GSSG) |  | 8 hours | 
| Acute change in insulinemia in response to a meal, by measuring insulin concentration in the blood at different time points |  | 8 hours |