Linear Stapler Versus Circular Stapler in Esophagojejunostomy

Study Overview
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Brief Summary
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With the development of stapler devices, various methods of esophagojejunostomy after laparoscopic total gastrectomy were evoluated. Which stapler is more advantageous has not been determined. At present, the most commonly used is linear stapler or Circular stapler in esophagojejunostomy. However, there is still a lack of reliable evidence for the selection of the two staplers. The purpose of this study is to explore the advantages of linear staper versus circular stapler in esophagojejunostomy for patients with gastric cancer who underwent total gastrectomy.

Detailed Description
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With the development of stapler devices, various methods of esophagojejunostomy after laparoscopic total gastrectomy were evoluated. Which stapler is more advantageous has not been determined. At present, the most commonly used is linear stapler or Circular stapler in esophagojejunostomy. However, there is still a lack of reliable evidence for the selection of the two staplers. The purpose of this study is to explore the advantages of linear staper versus circular stapler in esophagojejunostomy for patients with Siewert classification type II and III gastric cancer who underwent total gastrectomy.

Official Title
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Linear Stapler Versus Circular Stapler in Esophagojejunostomy for Patients With Gastric Cancer Underwent Laparoscopic Total Gastrectomy

Conditions
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Postoperative Complications, Operative Time, Hospital Costs

Intervention / Treatment
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* Device: Linear stapler
* Device: Circular stapler


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Histologically confirmed adenocarcinoma of the stomach, T1-T4 stages. Eastern Cooperative Oncology Group performance status of 0 or 1. Adequate organ function. Exclusion Criteria: Patients had distant metastasis. oesophageal invasion of more than 3 cm. Borrmann type 4 or large (more than 8 cm) type 3 carcinoma. Previous chemotherapy or radiation therapy for any other malignancies.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 90 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Linear stapler group<br>Linear stapler is adopted in esophagojejunostomy. | Device: Linear stapler<br>* Linear stapler is adopted in esophagojejunostomy<br>|
| Active Comparator: Circular stapler group<br>Circular stapler is adopted in esophagojejunostomy. | Device: Circular stapler<br>* Circular stapler is adopted in esophagojejunostomy<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Surgical complication | All surgical complication after laparoscopic total gastrectomy | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Operation duration | operation time | 1 day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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laparoscopy, total gastrectomy, esophagojejunostomy, linear stapler, circular stapler