Urinary Tract Infections in Older Persons Admitted to a Psychogeriatric Ward

Study Overview
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Brief Summary
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Urinary tract infections are one of the most common types of infections in older persons. The general aim of this study is to improve the epidemiological knowledge and develop a better diagnostic algorithm for urinary tract infections in older institutionalized individuals in order to reduce excessive prescribing of antibiotics and prevent antimicrobial resistance.

Official Title
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Optimizing and Validating the Clinical Algorithm for Diagnosing Urinary Tract Infections in Older Persons Admitted to a Psychogeriatric Ward

Conditions
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Urinary Tract Infections

Intervention / Treatment
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* Device: Diagnostic tests
* Device: Diagnostic tests


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Older (65+ years) persons admitted to a gerontopsychiatric ward Exclusion Criteria: Patients not understanding Dutch or not willing to participate (no informed consent)

Ages Eligible for Study
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Minimum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Diagnostic tests<br>For any patient with a suspected urinary tract infection during the course of the study a basic questionnaire will have to be filled out and diagnostic tests (urine sample for culture, dipstick assay for the detection of nitrites and leukocyte- esterase and a POC CRP test) will have to be perform. | Device: Diagnostic tests<br>* C Reactive Protein (CRP) measurement on capillary blood using a point-of-care test to determine C Reactive Protein level in the blood<br>Device: Diagnostic tests<br>* Uricult dipslide: Easy-to-perform bacterial culture test for dectecting urinary tract infections in point of care settings<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Serious infection | To verify if the elderly has a serious infection, the research team will combine test results (dipstick, dipslide and CRP measurement) with signs/symptoms reported in the patient questionnaire. | 2 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Reliability of the uricult dipslide in a population of institutionalized older patients | To verify the reliability of the uricult dipslide, a comparison will be made between the result of a dipslide read after 48h at room temperature, a dipslide incubated for 24h at +/- 35° Celsius and a urine culture test performed in a microbiology lab | 2 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Aged, Psychiatric Hospitals