Integrative Cognitive-Affective Therapy for Binge Eating Disorder

Study Overview
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Brief Summary
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The purpose of the study is to test a newly developed individual psychotherapy treatment for binge eating disorder in adults. This treatment is a type of individual psychotherapy called Integrative Cognitive-Affective Therapy (ICAT) that focuses on helping people change their behaviors, feelings, thoughts about themselves, and relationships. This new treatment is being compared to an existing treatment called Cognitive-Behavior Therapy-Guided Self Help (CBTgsh), which focuses on changing behavior patterns through the use of reading and homework assignments along with sessions with a therapist. The primary hypothesis of this investigation is that ICAT will be associated with greater reductions in binge eating at end of treatment and follow-up compared to CBTgsh.

Official Title
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Integrative Cognitive-Affective Therapy for Binge Eating Disorder

Conditions
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Binge Eating Disorder

Intervention / Treatment
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* Behavioral: Integrative Cognitive-Affective Therapy
* Behavioral: CBT-Guided Self Help


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Binge eating disorder (DSM-5) Exclusion Criteria: History of gastric bypass surgery Medical condition acutely affecting eating and/or weight Current medical and/or psychiatric instability (e.g., acute suicidality) Psychosis and/or bipolar disorder Severe cognitive impairment or developmental disability Inability to read English Current substance use disorder Current participation in psychotherapy and/or commercial weight loss program Change in dosage and/or frequency of psychotropic medication in the past 6 weeks Pregnant or breast feeding BMI < 21

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: CBT-Guided Self Help<br>Integrative Cognitive-Affective Therapy CBT-Guided Self Help | Behavioral: CBT-Guided Self Help<br>* CBT-Guided Self Help focuses on changing behavior patterns through the use of reading and homework assignments along with sessions with a therapist.<br>|
| Experimental: Integrative Cognitive-Affective Therapy<br>Integrative Cognitive-Affective Therapy is a psychotherapy treatment for binge eating that focuses on changing behaviors, feelings, thoughts, and relationships | Behavioral: Integrative Cognitive-Affective Therapy<br>* Integrative Cognitive-Affective Therapy is a psychotherapy treatment for binge eating that focuses on changing behaviors, feelings, thoughts, and relationships<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Binge Eating Episode Frequency (Eating Disorder Examination) | Frequency of binge eating as measured by the Eating Disorder Examination | 17 Weeks and 6-month Follow-up | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Global Eating Disorder Symptoms (EDE) | Global Eating Disorder Symptoms as measured by the Eating Disorder Examination | 17 Weeks and 6-month follow-up | 
| Symptoms of Depression (BDI) | Symptoms of Depression as measured by the Beck Depression Inventory | 17 Weeks and 6-month follow-up | 
| Symptoms of Anxiety (STAI) | Symptoms of Anxiety as measured by the State-Trait Anxiety Inventory | 17 Weeks and 6-month Follow-up | 
| Self-Esteem (RSEQ) | Self-esteem as measured by the Rosenberg Self-Esteem Questionnaire | 17 Weeks and 6-month Follow-up | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Binge Eating Disorder, Binge Eating, Eating Disorders, Obesity, Psychotherapy, Cognitive Behavioral Therapy