Effect of Connective Tissue Graft Position

Study Overview
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Brief Summary
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Aim: The aim of this study was to compare the root coverage and aesthetic results of CAF+ CTG positioned apical to the CEJ (CAF+CTG-ACEJ) with CAF+CTG positioned on the CEJ (CAF+CTG-CEJ) for treating isolated gingival recession defects. Methods: Thirthy-eight patients with Miller class I and II gingival recessions were enrolled. 19 patients were randomly assigned to the CAF+CTG-ACEJ group or CAF+CTG-CEJ group. Clinical and aesthetical evaluations were made at 6 months.

Official Title
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The Effects of Connective Tissue Graft Position on Clinical and Aesthetical Outcomes of Gingival Recession Treatment. A Controlled Randomized Clinical Trial

Conditions
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Gingival Recession

Intervention / Treatment
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* Procedure: Coronally advanced flap + connective tissue graft


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 19 years of age, Periodontally and systemically healthy, FMPS and FMBS <15%, Presence of Miller Class I/II GR defect (≥3 mm in depth) at the buccal aspect of incisors and canines, Presence of identifiable CEJ (step ≤1 mm at CEJ level and/or presence of a root irregularity/abrasion with identifiable CEJ, was accepted), No previous periodontal surgery. Exclusion Criteria: Smoking, Contraindications for surgery, Presence of recession defects associated with caries, deep abrasion, restoration or pulpal pathology.

Ages Eligible for Study
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Minimum Age: 19 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: CAF+ CTG positioned apical to the CEJ<br>Connective tissue graft covered by a coronally advanced flap which CTG apical of the CEJ level | Procedure: Coronally advanced flap + connective tissue graft<br>* connective tissue graft covered by a coronally advanced flap with connective tissue graft apical of the cementoenamel junction level<br>|
| Other: CAF+CTG positioned on the CEJ<br>Connective tissue graft covered by a coronally advanced flap which CTG on the CEJ level | Procedure: Coronally advanced flap + connective tissue graft<br>* connective tissue graft covered by a coronally advanced flap with connective tissue graft apical of the cementoenamel junction level<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Gingival Recession depth in millimeters | measured from the cemento-enamel junction to the gingival margin | 6 months | 
| keratinized tissue height in millimeters | measured from the mucogingival junction to the gingival margin | 6 months | 
| aesthetic evaluation assesed by visual analog scale |  | 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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connective tissue graft