Compensatory Kinematic Movements in Various Directions After Stroke

Study Overview
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Brief Summary
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This is cross-sectional study. By comparing kinematic analysis between stroke and healthy subjects in various directions, this investigation analyzes the compensatory kinematic movement for reaching task in stroke survivors

Detailed Description
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After Institutional Review Board approval, It recruits 2 groups. one group is elderly and another group is stroke survivors. the stroke group that meets the criteria. Another group is age matching of the stroke and not having an orthopedic or neurological disease. Participants of all the groups are assessed for kinematic by motion capture During reaching arm(affected side; stroke group, non-dominant side; healthy group) in 3 directions(medial_45, forward_90 and lateral_135 degrees). Retroreflective markers are placed on 11 anatomical place (3th metacarpal joint, both acromion, elbow lateral and medial epicondyle, lateral and medial styloid process, xyphoid process, sternum, C7, T4). Participants reach to a bell as quickly as possible in three directions. The subject reach to a bell 5 times in each direction and assess clinical evaluation such as Fugl Meyer Assessment, Postural Assessment Scale, Modified Ashworth Scale, shoulder-elbow range of motion and Trunk Instability scale.

Official Title
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Compensatory Kinematic Movement for Reaching Task in Various Directions in After Stroke

Conditions
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Cerebral Stroke, Hemiplegia, Spastic

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: The inclusion criteria used in the randomized controlled trials were as follows: Stroke Subject consisted of the physician's confirmation of chronic hemiplegia onset ≥ 6 months Mini-mental state examination≥25 Biceps ≤2, Triceps≤2 Ability to Sit on a chair alone FMA upper extremity score ≥ 21 points, FMA upper extremity ≤ 66 points Healthy Age of matching the stroke group Absence of neurological disease and orthopedic disease Exclusion Criteria: Stroke Biceps>2, Triceps>2 Flaccid Neglect syndrome Have neurological disease and orthopedic disease Lack of coordination

Ages Eligible for Study
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Minimum Age: 40 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| chronic stroke<br>The subject consisted of the physician's confirmation of chronic hemiplegia onset ≥ 6 months Mini-mental state examination≥25 Biceps ≤2, Triceps≤2 Ability to Sit on a chair alone FMA upper extremity score ≥ 21points, FMA upper extremity score ≤ 66 points The symptom is mild or moderate level (MAS≤2) and can sit alone. The subject reaches to target by affected arm in 3 directions(medial_45, forward_90 and lateral_135 degrees) | |
| Healthy<br>Matching aged people, not having neurological system or orthopedic disease on Upper extremity. The subject reaches to target by non-dominant arm in 3 directions(medial_45, forward_90 and lateral_135 degrees) | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Difference of the components temporal measurements between healthy and stroke | Hand velocity(peak velocity of 3th metacarpal phalangeal joint marker in reaching phase in millimetres per second; mm/s),total movement time in second, reaching time in second, number of movement units. elbow angular acceleration(elbow angular velocity per unit time; rad/sec2) and elbow angular velocity(time rate at which an object rotates, or revolves, about an axis, or at which the angular displacement between two forearm and humerus; rad/s) in reaching 3 directions(medial_45, forward_90 and lateral_135 degrees). Participants reach to a bell as quickly as possible. 3th joint is calculated for quantitative measurements. | 1 time(Baseline) | 
| Difference of the components spatial measurements between healthy and stroke | Trunk dislocation of reaching phase in millimetre; mm), elbow and shoulder angle in reaching in degree. The measurements are detected by 3 directions(medial_45, forward_90 and lateral_135 degrees). Participants reach to a bell as quickly as possible. 3th joint is calculated for quantitative measurements. | 1 time(Baseline) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Relationship between clinical score and kinematic variable in each direction | Related FMA score(dependent) to predictors(independent) in three directions. | 1 time(Baseline) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Chronic stroke, Reaching task, Motion capture