To Evaluate the Visual Performance After Bilateral Implantation of Multifocal Intraocular Lenses

Study Overview
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Brief Summary
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To evaluate the visual performance after bilateral implantation of multifocal intraocular lenses.

Detailed Description
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This study evaluates the visual performance after bilateral implantation of multifocal intraocular lenses (IOL). This prospective study is performed at the department of Ophthalmology, Goethe University, Frankfurt, Germany. Patients who received bilateral implantation of a multifocal intraocular lens pre-enrollment were included consecutively. Exclusion criteria were previous ocular surgeries excluding cataract surgery and refractive lens exchange, regular corneal astigmatism of >1.5 diopter, and ocular pathologies or corneal abnormalities. At 3 months postoperative examination included manifest refraction; monocular and binocular uncorrected (UCVA) and distance-corrected (DCVA) visual acuity in at far, intermediate at near distance (logMAR); slit-lamp examination. 3 months postoperatively defocus testing, binocular contrast sensitivity (CS) under photopic and mesopic conditions, and a questionnaire on subjective quality of vision, optical phenomena, and spectacle independence were performed.

Official Title
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Visual Performance of Multifocal Intraocular Lenses Following Removal of the Crystalline Lens

Conditions
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Visual Acuity

Intervention / Treatment
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* Procedure: Femtosecond-laser-assisted lens exchange


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: bilateral cataract surgery or refractive lens exchange with the implantation a multifocal intraocular lens a regular corneal astigmatism < 1.5 D measured with Pentacam (Oculus, Wetzlar, Germany) Exclusion Criteria: other previous ocular surgeries ocular pathologies corneal abnormalities endothelial cell count below 2000/mm²
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: Femtosecond-laser-assisted lens exchange|Bilateral implantation of multifocal intraocular lens (MIOL) following femtosecond-laser-assisted lens exchange|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Best corrected visual acuity at intermediate distance | Monocular and binocular corrected visual acuity at intermediate distance measured in logMAR 3 month after lens surgery | Measured 3 month after lens surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Best corrected visual acuity at far distance | Monocular and binocular best corrected visual acuity at far distance measured in logMAR 3 month after lens surgery | Measured 3 month after lens surgery | 
| Best corrected visual acuity at near distance | Monocular and binocular best corrected visual acuity at near distance measured in logMAR 3 month after lens surgery | Measured 3 month after lens surgery | 
| Uncorrected visual acuity at far distance | Monocular and binocular uncorrected visual acuity at far distance measured in logMAR 3 month after lens surgery | Measured 3 month after lens surgery | 
| Uncorrected visual acuity at intermediate distance | Monocular and binocular uncorrected visual acuity at intermediate distance measured in logMAR 3 month after lens surgery | Measured 3 month after lens surgery | 
| Uncorrected visual acuity at near distance | Monocular and binocular uncorrected visual acuity at near distance measured in logMAR 3 month after lens surgery | Measured 3 month after lens surgery | 
| Binocular contrast sensitivity (CS) under photopic, mesopic, and mesopic with glare lighting conditions | Binocular contrast sensitivity (CS) was measured under photopic, mesopic (0.167 cd/m²), and mesopic with glare lighting conditions by means of the Frankfurt-Freiburg Contrast and Acuity Test System (FF-CATS) | Measured 3 month after lens surgery | 
| Defocus curve testing | Defocus curve (monocular and binocular) was tested from -5.0 D to +2.0 D in 0.5 D steps under photopic lighting conditions (ETDRS). | Measured 3 month after lens surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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visual outcomes, multifocal intraocular lens, patient satisfaction, spectacle independence