Antibiotic Prophylaxis in Adult Heart Transplantation: a French National Survey

Study Overview
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Brief Summary
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The study focuses on the antibiotic prophylaxis use in adult heart transplantation in France.

Detailed Description
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In adult heart transplantation, clinical situations differ between patients (elective, emergency, redux surgery, ventricular assisting device or extracorporeal live saving). At investigator's knowledge, there is not recommendations in France about antibiotic prophylaxis in adult heart transplantation. So, investigators aimed to study the antibiotic prophylaxis use in adult heart transplantation in France. Investigators conduct a French national survey about antibiotic prophylaxis used in adult heart transplantation center. Clinical situations such as elective, emergency, redux surgery, ventricular assisting device or extracorporeal live saving are investigated. Study was performed after Institutional approval was obtained from the local Ethics Committee (Comite de Protection des Personnes Nord Ouest III). An electronic survey was sent to all French adult heart transplantation centers (22) on march 1st, 2015. Reminders were planned on week 2 and 4 after initial sending. On june 2015, nonresponding centers were contacted by phone. Data were collected by a single investigator.

Official Title
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Antibiotic Prophylaxis in Adult Heart Transplantation: a French National Survey

Conditions
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Antibiotic Prophylaxis, Adult Heart Transplantation

Intervention / Treatment
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* Procedure: Antibiotic prophylaxis in adult heart transplantation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All French centers performing adult heart transplantation in 2015 Exclusion Criteria: not responding center no adult heart transplantation

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| French Adult Heart Transplantation Center<br>All center performing adult heart transplantation in France in 2015. | Procedure: Antibiotic prophylaxis in adult heart transplantation<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Class of antibiotic used as prophylaxis in adult heart transplantation |  | one year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Class of antibiotic used as prophylaxis in adult heart transplantation in regard to clinical situation | elective, emergency, redux surgery, ventricular assisting device or extracorporeal live saving | one year | 
| Fungal prophylaxis in adult heart transplantation |  | one year | 
| Other prophylactic measures (isolation, specific room, family visits) used in adult heart transplantation |  | one year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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antibiotic prophylaxis heart transplantation