Radial Artery Stenosis Following PiCCO Catheter Implementation

Study Overview
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Brief Summary
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Cardiac output monitoring devices are commonly used in ICU patients. The most precise use direct measurement, which require artery cannulation. The gold standard is Swan-Ganz catheter, but it is a very invasive technique. PiCCO (Pulse index Continuous Cardiac Output) is the alternative way of haemodynamic monitoring. This technology is the easy, less invasive and cost-efficient tool for determining the main hemodynamic parameters of critically ill patients. It is based on two physical principles - transpulmonary thermodilution and pulse contour analysis. Both principles allow the calculation of haemodynamic parameters in critically ill patients. PiCCO method requires peripheral artery cannulation. Cannulation may be followed by artery stenosis. Aims of the study are: to verify the occurrence of radial artery stenosis after 3 days of having a PiCCO cannula in place. whether 5 days cannulation of radial artery with PiCCO catheter is related to more frequent stenosis rate. An additional assessment: 1. to check whether the eventual stenosis is still present after 3, 14 and 30 days after decannulation - assessment depending on patients availability

Detailed Description
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Barbeau test and Doppler - ultrasonography preceded radial artery cannulation. Catheter removal (after 3 or 5 days of cannulation) is followed by Doppler - usg. Usg -Doppler is performed also 3, 14 and 30 days after decannulation - depending on patient being available

Official Title
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Occurrence of Radial Artery Stenosis Following PICCO Catheter Cannulation

Conditions
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Artery Stenosis

Intervention / Treatment
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* Other: 3 days cannulation
* Other: 5 days cannulation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: critically ill patients with haemodynamic monitoring required Exclusion Criteria: Barbeau test type D in radial artery artery inaccessible for cannulation - based on doppler ultrasonography

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 3 days cannulation<br>radial artery cannula removed after 3 days | Other: 3 days cannulation<br>* assessment of artery stenosis after 3 days of artery cannulation<br>|
| Experimental: 5 days cannulation<br>radial artery cannula removed after 5 days | Other: 5 days cannulation<br>* assessment of artery stenosis after 5 days of artery cannulation<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of patients with artery stenosis after radial artery decannulation, confirmed by Doppler ultrasonography | in one group usg, following decannulation will be performed 3 days after cannulation, in the second group - decannulation and usg will be done 5 days after cannulation. | up to 5 days after cannulation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of patients with persistent artery stenosis after radial artery decannulation, confirmed by Doppler ultrasonography | usg will be performed 3, 14 and 30 days after decannulation; depending on patients availability | 3, 14 and 30 days after decannulation | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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artery cannulation, haemodynamic monitoring