Efficacy of Intraoperative Surgical Scrubbing in Reducing Bacterial Load After Nail Removal Surgery

Study Overview
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Brief Summary
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The investigators conducted a controlled, prospective randomized study to examine the antiseptic efficacy of intraoperative irrigation methods during nail avulsion surgery.

Detailed Description
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The investigators conducted a controlled, prospective randomized study to examine the antiseptic efficacy of intraoperative scrubbing methods during nail avulsion surgery. The investigators compared intraoperative antiseptic scrubbing using 0.9% saline solution and 0.1% polihexanide. Swab samples were taken from each patient at 5 distinct stages throughout the surgical procedure, and bacterial culture analysis was performed (positive culture rate, total inocula count, reduction of bacterial load, and identification of specific microorganisms).

Official Title
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Efficacy of Intraoperative Surgical Scrubbing in Reducing Bacterial Load After Nail Removal Surgery

Conditions
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Skin Diseases, Nail Diseases, Nails, Ingrown

Intervention / Treatment
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* Drug: Polihexanide


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Older than 18 Onychocryptosis Exclusion Criteria: infection a history of tinea pedis onychomycosis paronychia nail trauma or subungual hematoma nail deformities and disorders peripheral vascular disease or diabetes cardiac disease a history of rheumatic fever recent antibiotic use or current antimicrobial therapy a history of steroid use and recent nail polish use

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Sterile Saline solution<br>The investigators compared intraoperative antiseptic irrigation using 0.9% saline solution and 0.1% polihexanide. | Drug: Polihexanide<br>* The investigators compared intraoperative antiseptic irrigation using 0.9% saline solution and 0.1% polihexanide.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| bacterial count (CFU/cm2) | The percentage of inoculum reduction at the irrigation step was calculated as follows: percentage of inoculum reduction = 100 e (1003 Ii)/Is, where Ii is the bacterial count (CFU/cm2) at the irrigation step and Is is the inoculum (CFU/cm2) at the surgery step. Bacteria were identified using standard laboratory methods. The limit of detection in the nailfold test was 1.33 CFU/cm2. | Participants will be followed until the surgery to heal completely,an expected average of 7 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Skin Diseases [C17.800], Nail Diseases [C17.800.529], Nails, Ingrown [C17.800.529.406]