Cognitive Impairments in Children With Epilepsy

Study Overview
=================
Brief Summary
-----------------
Since the proportion of language and attentional difficulties in patients with epilepsy is recognized, both in the literature and in the clinical experience of practitioners, it is appropriate to propose a complete speech-language assessment of oral language and attention.This study investigates these impairments through the taking of specific tests. The general objective of this study is to observe possible oral language and attention disorders in children with epilepsy, by age and etiology of epilepsy. The objective of this work is to study therapeutic apheresis (including plasma exchange and immunoadsorption) among french neuropediatric tertiary centers and to prove that this treatment modality is effective and well tolerated in pediatric neurology diseases.

Official Title
-----------------
Interest of Speech Therapy in Children With Epilepsy: What Impairments of Cognitive Functions?

Conditions
-----------------
Epilepsy Syndrome

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion criteria: The subjects should : Be at least 3 years old and at most 15 years old Be French speaker Be in a regular class Have a diagnosis of epilepsy Exclusion criteria: Subjects schooled in IEM Subjects diagnosed with austim spectrum disorder Subjects with a motor or visual handicap Subjects with psychiatric disorders

Ages Eligible for Study
-----------------
Minimum Age: 3 Years
Maximum Age: 15 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Score in the different tests assessing oral language | Test assessing oral language : Oral naming of images Oral designation of images Morphosyntactic comprehension test Syntactic production test The scores obtained in the various tests are organized into 7 classes: Class 1 = percentiles less than 7 : pathological zone Class 2 = 7 to 20 percentiles : fragile zone / weak zone Class 3 = 21 to 38 percentiles : low standard zone Class 4 = percentiles 39 to 62 : median standard zone / expected average results for age or grade level Class 5 = 63 to 80 percentiles : higher standard zone Classes 6 and 7 = respectively 81 to 93 percentiles and percentiles greater than 93 : zone with results well above the norm for age or grade level. | day 1 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Score in the different tests assessing attention | Tests assessing attention : Visual attention test Auditive attention test The scores obtained in the various tests are organized into 7 classes: Class 1 = percentiles less than 7 : pathological zone Class 2 = 7 to 20 percentiles : fragile zone / weak zone Class 3 = 21 to 38 percentiles : low standard zone Class 4 = percentiles 39 to 62 : median standard zone / expected average results for age or grade level Class 5 = 63 to 80 percentiles : higher standard zone Classes 6 and 7 = respectively 81 to 93 percentiles and percentiles greater than 93 : zone with results well above the norm for age or grade level. | day 1 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Speech therapy, Neurology, Children, Oral language, Attention, Type of epilepsy (focal epilepsy or generalized epilepsy), Etiology of epilepsy (unknown, idiopathic, structural, metabolic, immune, infectious), Epilepsy syndrome