Ultrasound-guided Continuous Proximal Adductor Canal vs Continuous Femoral Nerve Block for Postoperative Pain Control and Rehabilitation Following Total Knee Arthroplasty

Study Overview
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Brief Summary
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The purpose of the study is to compare continuous femoral nerve block with continuous proximal adductor canal block for postoperative pain control and rehabilitation.

Detailed Description
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Patients meeting the criteria: American Society of Anesthesiologists (ASA) class I and II, that are scheduled for elective total knee arthroplasty, will be recruited into the study. Subjects will be randomized into 2 groups: those who will receive a continuous proximal adductor canal block (ACB) and those who will receive a continuous femoral nerve block (FNB).

Official Title
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Ultrasound-guided Continuous Proximal Adductor Canal Versus Continuous Femoral Nerve Block for Postoperative Pain Control and Rehabilitation Following Total Knee Arthroplasty

Conditions
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Total Knee Arthroplasty

Intervention / Treatment
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* Procedure: Continuous proximal adductor canal block
* Procedure: Continuous femoral nerve block


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients with an American Society of Anesthesiologists Physical Status Classification System (ASA) score of 1 or 2 that are healthy without systemic disease or have mild systemic disease, respectively. The patient will need to be able to have decision-making capacity and ability to consent for the study. Exclusion Criteria: Patients with an American Society of Anesthesiologists Physical Status Classification System (ASA) score greater than 2. Patients unable to have decision-making capacity and ability to consent for the study.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: adductor canal block (ACB)<br>Subjects randomized to this groups receive a continuous proximal adductor canal block (ACB) during surgery. | Procedure: Continuous proximal adductor canal block<br>* Subjects will be randomized into 2 groups: those who will receive a continuous proximal adductor canal block (ACB) and those who will receive a continuous femoral nerve block (FNB).<br>* Other names: ACB;|
| Active Comparator: femoral nerve block (FNB)<br>Subjects randomized to this groups receive a continuous femoral nerve block (FNB) during surgery. | Procedure: Continuous femoral nerve block<br>* Subjects will be randomized into 2 groups: those who will receive a continuous proximal adductor canal block (ACB) and those who will receive a continuous femoral nerve block (FNB).<br>* Other names: FNB;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Motor effects | Subjects' change in motor effects will be assessed as maximum voluntary isometric contraction (MVIC) in the quadriceps muscle. | 24 hours (postoperatively) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain score | Subjects' pain will be assessed using a numerical pain score, where 10 is the greatest amount of pain. | On average between 6 and 8 hours postoperatively | 
| Pain score | Subjects' pain will be assessed using a numerical pain score, where 10 is the greatest amount of pain. | 24 hours (postoperatively) | 
| Opioid consumption | Subjects' pain will be assessed by tracking opioid consumption postoperatively. | On average between 6 and 8 hours postoperatively | 
| Opioid consumption | Subjects' pain will be assessed by tracking opioid consumption postoperatively. | 24 hours (postoperatively) | 
| Motor effects | Subjects' change in motor effects will be assessed as maximum voluntary isometric contraction (MVIC) in the quadriceps muscle. | On average between 6 and 8 hours postoperatively | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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continuous femoral nerve block (FNB), a continuous proximal adductor canal block (ACB)