linjc16/ctgov huggingface dataset:
Views of Nurses on Alarm Fatigue in ICUs

Study Overview
=================
Brief Summary
-----------------
This study focused on determining the views of nurses on alarm fatigue and its reduction in adult intensive care units.

Detailed Description
-----------------
Backround: Physiological monitoring of critically ill patients in ICU is a complex nursing task, and nurses are key professionals managing multiple monitoring devices. Aim: The aim of this study is to determine the views of nurses on alarm fatigue and its prevention in adult intensive care units. Study Design: In the study, the minimum sample size was calculated as 67 for a population size of 106 and a 95% confidence interval, taking into account the alarm fatigue standard deviation (σ=6.82) found in the Turkish validity study of the Nurses' Alarm Fatigue Scale (t=1.96; d=1) . Considering that there may be losses, 74 nurses will be included in the study by taking 10% more. In the qualitative phase of the research, intensive care nurses who agreed to be interviewed during the collection of quantitative data will be included. Method: In this study, parallel data type will be used in convergent parallel mixed design. The quantitative phase of the study is a descriptive study to determine alarm fatigue levels in nurses working in adult intensive care units. In the qualitative phase of the research; A case study will be conducted at the same time in order to examine the findings revealed with quantitative data in more depth and to determine the views of nurses on reducing alarm fatigue. Individual in-depth interviews will be held in a suitable room using the Semi-Structured Interview Form created by the researchers with those who agree to participate in the qualitative study.

Official Title
-----------------
Nurses' Views on Alarm Fatigue and Its Reduction in Adult Intensive Care Units: Convergent Parallel Design

Conditions
-----------------
Nurse's Role

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 18 years and older Who volunteered to participate in the research Working in adult intensive care units Exclusion Criteria: Under the age of 18 Not working in adult intensive care unit

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Nurses' Alarm Fatigue Scale | The scale consists of 9 items and the score range is between 0-36. High scores indicate the effects of alarm fatigue on nurses' performance. Each item in the questionnaire is scored between 0 and 4. | 30 May 2022 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Alarm fatigue, Intensive care, Nursing, Mixed method
COPD Rehabilitation in Primary and Secondary Health Care

Study Overview
=================
Brief Summary
-----------------
Pulmonary rehabilitation of COPD patients are implemented in a non-randomized manner in two settings: primary and secondary health care. The effect on quality of life and hospitalizations will be evaluated

Official Title
-----------------
Comparison of Pulmonary Rehabilitation of Patients With Chronic Obstructive Pulmonary Disease in Primary and Secondary Health Care

Conditions
-----------------
Chronic Obstructive Pulmonary Disease

Intervention / Treatment
-----------------
* Procedure: pulmonary rehabilitation programme


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: COPD patients Exclusion Criteria: severe concomitant chronic disease

Ages Eligible for Study
-----------------
Minimum Age: 0 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: pulmonary rehabilitation programme|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
COPD, rehabilitation, health services research
High Agreement Between the Danish Ventral Hernia Database and Hospital Files in Region Zealand

Study Overview
=================
Brief Summary
-----------------
Is there agreement between data in the Danish Ventral Hernia Database and patient files

Official Title
-----------------
High Agreement Between the Danish Ventral Hernia Database and Hospital Files in Region Zealand

Conditions
-----------------
Data Agreement Between a Database and Hospital Files After a Ventral Hernia Repair

Intervention / Treatment
-----------------
* Procedure: Ventral hernia repair


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: All ventral hernia repairs

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 120 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| patients with a ventral hernia repair<br>All patients with a ventral hernia repair performed in Region Zealand and registered in The Danish Ventral Hernia Database during October 1st 2010 to October 1st 2011 | Procedure: Ventral hernia repair<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Data agreement | Compare information registered in The Danish Ventral Hernia Database with information obtained from patient files | 1 year |
Anal Motor Function in Fecal Incontinence

Study Overview
=================
Brief Summary
-----------------
Traditionnal measurment of anorectal function is perfomed with manometric device using 2 to 3 pressure sensors. The investigators aim to evaluate the usefulness of high resolution manometry to measure anorectal motility

Detailed Description
-----------------
Measurment of anorectal function is traditionnaly made using manometric device composed of perfused or ballon catheters. This allows the recording of anorectal pressure on 2-3 sites. Recently, high resolution manometryu devices using > 36 pressure channels have been developped. The investigators therefore aim to evaluate the usefullness of the high resolution manometry in patient with fecal incontinence in terms of feasability and diagnosis accuracy

Official Title
-----------------
Measure of Ano-rectal Motility in Fecal Incontinence

Conditions
-----------------
Fecal Incontinence

Intervention / Treatment
-----------------
* Device: High resolution manometry


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patient with fecal incontinence (group fecal incontinence subject without significant medical or surgical hisotry (group healthy controls) Exclusion Criteria: pregnacy unable to speack/understand French language not affilitated to the French healthcare system history of anorectal disease (for the group of healthy controls) including fecal incontinence, or protocologic surgery constipation diarrhea

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Fecal incontience<br>Patient with fecal incotinence who will be explored using high resoltuion manometry | Device: High resolution manometry<br>* Anorectal High resoltion manometry using electronic sensors<br>|
| Healthy controls<br>Healthy volunteers who will be explored using high resoltuion manometry | Device: High resolution manometry<br>* Anorectal High resoltion manometry using electronic sensors<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Anal squeezing pressure | measurement of anal squeezing pressure (mmhg) | Day 1 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| anal tone pressure | measurement of anal tone pressure (mmhg) | day 1 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Fecal incontinence, ano-rectal manometry
Prevalence of Gastroesophageal Reflux Disease in Peritoneal Dialysis and Hemodialysis Patients

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to determine the prevalence of GERD among chronic kidney disease with peritoneal dialysis and hemodialysis in Korea.

Detailed Description
-----------------
Gastroesophageal reflux disease is a common upper gastrointestinal disorder in chronic kidney disease. But, little is known about the prevalence in dialysis patients. The aims of this study were to determine the prevalence of GERD among chronic kidney disease with peritoneal dialysis and hemodialysis in Korea.

Official Title
-----------------
Prevalence of Gastroesophageal Reflux Disease in Peritoneal Dialysis and Hemodialysis Patients

Conditions
-----------------
Gastroesophageal Reflux Disease

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: peritoneal dialysis and hemodialysis patients Exclusion Criteria: a history of abdominal surgery or with a proton pump inhibitor before 1 month and a eradication of H. pylori were excluded
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| hemodialysis patients<br> | |
| Peritoneal dialysis patients<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| prevalence of GERD among chronic kidney disease with peritoneal dialysis and hemodialysis |  | 2 yrs | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| risk factor for GERD in peritoneal dialysis and hemodialysis patients |  | 2 yrs | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Gastroesophageal Reflux Disease, peritoneal dialysis, hemodialysis
Mind-Body Exercise for COPD: A Pilot Study

Study Overview
=================
Brief Summary
-----------------
This is a pilot randomized controlled trial of feasibility and preliminary effects of a 12 week tai chi intervention vs. usual care in patients with chronic obstructive pulmonary disease

Official Title
-----------------
Tai Chi Exercise in Patients With Chronic Obstructive Pulmonary Disease

Conditions
-----------------
COPD

Intervention / Treatment
-----------------
* Behavioral: Tai Chi exercise


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: physician diagnosis of COPD FEV1<65% of predicted and FEV1/FVC<0.70 ≥45 years old Exclusion Criteria: COPD exacerbation requiring ER visit or hospitalization within past month planned major pulmonary intervention in coming 3 months severe peripheral vascular disease/claudication or other physical condition precluding walk test inability to perform bicycle ergometry severe cognitive dysfunction (MMSE ≤ 24) inability to speak English current participation in a pulmonary rehabilitation or regular practice of tai chi

Ages Eligible for Study
-----------------
Minimum Age: 45 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: Usual Care<br> | |
| Experimental: Tai Chi<br> | Behavioral: Tai Chi exercise<br>* 12-week tai chi exercise class<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Study feasibility |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Quality of life |  |  | 
| Exercise capacity |  |  |
Early Diagnosis of Malignant Transformation of Pigmentary Skin Lesions

Study Overview
=================
Brief Summary
-----------------
Malignant Melanoma is a deadly skin cancer that can be cured if diagnosed early. To date atypical pigmented skin lesions are diagnosed by appearance alone and many moles and lesions are excised unnecessarily and on the other hand malignant lesions are missed and diagnosed too late. In this study a protein conjugated to a florescent dye is spread on a suspicious pigmented lesion, the hypothesis is that this protein binds to malignant cells only and thus with a special camera that picks up the dye we can find pigmented lesions with early malignant transformation.

Official Title
-----------------
Early Diagnosis of Malignant Melanoma Transformation in Pigmentary Skin Lesions

Conditions
-----------------
Malignant Melanoma, Pigmented Nevi, Skin Neoplasm

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: pigmented lesion indicated for surgical excision over 18 years of age Exclusion Criteria: pregnancy

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
Lipid Efficacy/Tolerability Study (0524A-020)

Study Overview
=================
Brief Summary
-----------------
A 28-week clinical trial in patients with primary hypercholesterolemia or mixed hyperlipidemia to study the effects of MK0524A on lipids and tolerability. There will be 9 scheduled clinic visits, and 3 treatment groups. A patient can be randomly assigned to 1 of the 3 treatment groups.

Official Title
-----------------
A Worldwide, Multicenter, Double-Blind, Randomized, Parallel, Placebo-Controlled Study to Evaluate the Lipid-Altering Efficacy, Safety and Tolerability of MK0524A in Patients With Primary Hypercholesterolemia or Mixed Hyperlipidemia

Conditions
-----------------
Primary Hypercholesterolaemia, Mixed Hyperlipidaemia

Intervention / Treatment
-----------------
* Drug: niacin (+) laropiprant
* Drug: ER-niacin


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients 18 to 85 years of age with Primary Hypercholesterolemia or Mixed Hyperlipidemia with LDL-C below 100 mg/dL for high risk patients (patients with Coronary Artery Disease (CHD). Have medical conditions considered to be CHD equivalent). LDL-C below 130 mg/dL for patients with multiple risk factors. LDL-C between 130 and 190 mg/dL for patients with low risk and Triglycerides </= to 350 mg/dL. Exclusion Criteria: A condition which, in the opinion of the investigator, might pose a risk to the patient or interfere with participating in the study, patients < 20% compliance, patients with chronic medical conditions, patients with unstable doses of medications. Pregnant or lactating women, or women intending to become pregnant are excluded. Patient with diabetes mellitus that is poorly controlled, newly diagnosed, has recently experienced repeated hypoglycemia or unstable glycemic control, or is taking new or recently adjusted antidiabetic pharmacotherapy (with the exception of +/- 10 units of insulin). Patients with the following conditions: chronic heart failure, uncontrolled/unstable cardiac arrhythmias, unstable hypertension, active or chronic hepatobiliary or hepatic disease, HIV positive, gout (within 1 year).

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: niacin (+) laropiprant|Duration of Treatment - 24 weeks|
|Drug: ER-niacin|Duration of Treatment - 24 weeks|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Reductions of LDL-C concentrations at 24 weeks and better tolerability |  | at 24 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Elevations in HDL-C concentrations at 24 weeks |  | at 24 weeks |
Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults With Repaired or Palliated Conotruncal Cardiac Defects

Study Overview
=================
Brief Summary
-----------------
OBJECTIVES: I. Identify latent hypoparathyroidism in normocalcemic adult survivors with repaired conotruncal cardiac defects, by evaluating parathyroid gland secretory function after induced hypocalcemia. II. Determine the relationship of parathyroid hormone secretion to microdeletions in the same region of chromosome 22q11 as found in patients with DiGeorge anomaly.

Detailed Description
-----------------
PROTOCOL OUTLINE: Patients are given sodium citrate over a 2 hour infusion on day 1. Blood is drawn at times -30, -15, 0, and every 10 minutes thereafter during the infusion. On day 2, patients are given calcium gluconate over a 2 hour infusion. Blood is drawn at times -30, -15, 0, and every 10 minutes thereafter during the infusion.

Conditions
-----------------
Hypoparathyroidism, Tetralogy of Fallot, Pulmonary Valve Stenosis, Conotruncal Cardiac Defects, Heart Defects, Congenital, Pulmonary Atresia

Intervention / Treatment
-----------------
* Drug: calcium gluconate
* Drug: sodium citrate


Participation Criteria
=================
Eligibility Criteria
-----------------
Diagnostically shown repaired or palliated conotruncal cardiac defects, including tetralogy of Fallot with pulmonary stenosis or pulmonary atresia, truncus arteriosus, or interrupted aortic arch type B

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: calcium gluconate|nan|
|Drug: sodium citrate|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
DiGeorge syndrome, cardiovascular and respiratory diseases, conotruncal cardiac defects, endocrine disorders, genetic diseases and dysmorphic syndromes, hypoparathyroidism, pulmonary valve stenosis, rare disease, tetralogy of Fallot
Assessment of Wall Thickness in Hypertrophic Cardiomyopathy

Study Overview
=================
Brief Summary
-----------------
Assessment of wall thickness in hypertrophic cardiomyopathy (HCM) is of diagnostic and prognostic importance given its known association with sudden cardiac death. However, data regarding comparison of imaging modalities for this key measurement is lacking. This study seeks to compare assessment of maximum wall thickness between clinically indicated echocardiography (with and without contrast) and clinically indicated cardiac magnetic resonance imaging.

Detailed Description
-----------------
Patients receiving clinically indicated echocardiograms and cardiac magnetic resonance imaging at Mayo Clinic will be eligible.

Official Title
-----------------
Assessment of Wall Thickness in Hypertrophic Cardiomyopathy

Conditions
-----------------
Hypertrophic Cardiomyopathy

Intervention / Treatment
-----------------
* Procedure: Noncontrast echocardiography
* Procedure: Contrast Echocardiography
* Procedure: Cardiac magnetic resonance imaging


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Clinically and echocardiographically defined hypertrophic cardiomyopathy. Clinically indicated transthoracic echocardiography as part of the medical evaluation. No contradiction to administration of ultrasonic echocardiography contrast. Planned clinically indicated cardiac magnetic resonance imaging as part of medical evaluation. No contraindication to cardiac magnetic resonance imaging (such as cochlear implants, central nervous system aneurysm clips and other implanted medical devices). Age 18 years and older Exclusion Criteria: 1) Insufficient image quality for determination of maximal wall thickness.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Subjects with HCM<br>All subjects will undergo noncontrast echocardiography, contrast echocardiography and cardiac MRI. | Procedure: Noncontrast echocardiography<br> <br> Procedure: Contrast Echocardiography<br> <br> Procedure: Cardiac magnetic resonance imaging<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Left Ventricular Wall Thickness | All subjects will undergo noncontrast echocardiography, contrast echocardiography and cardiac MRI. | approximately 1 week after enrollment | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Echocardiography, hypertrophic cardiomyopathy, cardiomyopathy, magnetic resonance imaging, contrast