Studying a New Piece of Equipment That Can Help Plan Radiation Therapy of the Spine

Study Overview
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Brief Summary
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Participants will receive an MRI with a custom-built MRI coil for each participant. The purpose is to find out whether this custom-built MRI coil can help doctors see the different parts of the spine as well as or better than they can with standard CT myelograms.

Official Title
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Assessment of a Custom-Built MRI Coil for Spine Radiotherapy Treatment Planning

Conditions
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Thoracic Cancer, Spine Cancer, Thoracic Diseases, Spine Disease, Thoracic Neoplasms, Spine Metastases

Intervention / Treatment
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* Diagnostic Test: MRI with custom MRI spine coil


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: >/= 18 years of age at the time of treatment Able to give informed consent Consented for spine stereotactic radiation therapy No contraindications for CT myelograms which include: Allergy to CT contrast Use of phenothiazines Platelet count < 60,000 K/mcl INR > 1.5 VEGF inhibitor use in the past 2 weeks prior to myelogram NSAID use in the past 5 days prior to myelogram Renal disease Creatinine > 1.2 mg/dL No contraindications for MRI scans which include: Newly placed glucose monitors Tattoos (Tattoos for radiation therapy are allowed) Presence of a cardiac pacemaker Presence of an implanted cardioverter defibrillator Breast tissue expander Aneurysm clip Any other implanted metallic (BB, bullet, shrapnel, IUD, metallic stent or filter, spinal cord simulator etc.) or electronic device which is considered MR unsafe Severe claustrophobia or inability to lie flat for the duration of the study, etc. Exclusion Criteria: Presence of surgical spine hardware at the region of interest Presence of cervical spine lesions History of claustrophobia

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Thoracic, lumbar and sacral spine lesions<br>Participants will have thoracic, lumbar and sacral spine lesions | Diagnostic Test: MRI with custom MRI spine coil<br>* Participants will undergo MRI with custom MRI spine coil<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Difference of calculated doses to the cauda equine and spinal cord based upon MRI coil vs CT myelogram used to define each structure | The calculated doses to the cauda equine and spinal cord will be compared and evaluated for significant difference based upon the imaging modality (MRI coil vs CT myelogram) used to define each structure, with all other target and avoidance volumes being equal in the same patient. | 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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MRI Coil, Thoracic lesions, Lumbar lesions, Sacral spine lesions, spine radiotherapy, Memorial Sloan Kettering Cancer Center, 19-476