The Impact of ERAS Program in Cardiac Surgery on Patient Prognosis

Study Overview
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Brief Summary
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The aim of the study is to develop, verify and optimize the ERAS protocol for cardiac surgery.

Detailed Description
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The aim of the study is to develop, verify and optimize the ERAS protocol for cardiac surgery, thereby improving the overall prognosis of cardiac surgery patients, reducing the incidence of complications, and shortening the length of hospital stay.

Official Title
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The Impact of ERAS Program in Cardiac Surgery on Patient Prognosis

Conditions
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ERAS

Intervention / Treatment
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* Other: Nutrition
* Other: Control Blood Glucose
* Drug: Fasting
* Behavioral: Smoking and Alcohol
* Other: Control Anemia
* Other: Blood Transfusion
* Other: GDFT
* Other: Remove the tracheal tube
* Behavioral: Eating and Drinking
* Other: Prevent Thrombosis


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: ASA II/III BMI 16.5-31 kg/㎡ Elective cardiac surgery under CPB Volunteer to participate and sign informed consent Exclusion Criteria: Redo cardiac surgery Patients who do not cooperate or cannot communicate Abusers of alcohol, drugs or narcotics Pregnant or Breastfeeding

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: ERAS<br> | Other: Nutrition<br>* Correct the patient's low nutritional status before surgery.<br>Other: Control Blood Glucose<br>* Control the patient's blood glucose before surgery, fasting blood glucose level ≤ 8mmol/L or HbA1c ≤ 7%.<br>Drug: Fasting<br>* Take 10% glucose water 6ml/kg 2 to 4 hours before operation (except for diabetes).<br>Behavioral: Smoking and Alcohol<br>* Quit smoking and alcohol before surgery<br>Other: Control Anemia<br>* Correct anemia before surgery<br>Other: Blood Transfusion<br>* Use strict blood transfusion indications and blood protection strategy during surgery.<br>Other: GDFT<br>* Use goal-directed fluid therapy during surgery.<br>Other: Remove the tracheal tube<br>* Remove the tracheal tube as soon as possible after surgery.<br>Behavioral: Eating and Drinking<br>* Eat and drink as soon as possible after extubation after surgery.<br>Other: Prevent Thrombosis<br>* Actively prevent thrombosis after surgery.<br>|
| No Intervention: Control<br> | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Length of hospital stay |  | Within 1 month after surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Duration of mechanical ventilation after surgery |  | Within 1 week after surgery | 
| Length of ICU stay |  | Within 1 month after surgery | 
| Mortality |  | Within 1 month after surgery | 
| Overall hospitalization costs |  | Within 3 months after surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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ERAS, Cardiac surgery