Efficacy Study of Rectus Sheath Block to Control Postoperative Pain

Study Overview
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Brief Summary
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The aim of this study is to evaluate the effect of the ultrasound guided rectus sheath block (RSB) on both intraoperative sevoflurane consumption and postoperative analgesia.

Detailed Description
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Prospective, randomized study.Forty patients with American Society of Anaesthesiologists (ASA) I-II physical status, aged 3-15 years.Patients are randomly allocated into two groups and are administered general anesthesia and before the beginning of surgery ultrasound guided RSB with 0.2 ml.kg-1, 0.25% of levobupivacaine and thirty minutes before the surgery the loading dose of morphine of 0.1 mg.kg-1 intravenously are received in group RSB and group M, respectively. Patient controlled analgesia (PCA) device with 0.01 mg.kg-1 bolus dose of morphine and 30 minutes lockout interval is set up postoperatively in both groups.

Official Title
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The Effect of Ultrasound Guided Rectus Sheath Block on Postoperative Analgesia After Laparotomy With Transverse Incision in Children

Conditions
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Pain, Postoperative

Intervention / Treatment
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* Procedure: ultrasound guided rectus sheath block
* Drug: Morphine


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: ASA physical status I-II 3-15 years of age children Abdominal surgery including liver, gall bladder, spleen, small intestine, cecum, colon, rectum, intra-abdominal masses, umbilical, paraumbilical, and inguinal hernia with transverse incision Exclusion Criteria: ASA physical status III and above Parents who did not consider to participate in the study Having systemic (septicemia, bacteremia) or local infection, bleeding and shock, predisposition for bleeding and anticoagulant therapy given, central nervous system disease, allergy to local anesthetics, severe respiratory, hepatic, and renal failure

Ages Eligible for Study
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Minimum Age: 3 Years
Maximum Age: 15 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: ultrasound guided rectus sheath block<br>Ultrasound guided rectus sheath block | Procedure: ultrasound guided rectus sheath block<br>* the application of rectus sheath block with ultrasound guidance<br>* Other names: US guided rectus sheath block;|
| Active Comparator: iv morphine<br>0.1 mg.kg-1 loading dose of morphine by intravenous route in intraoperative period | Drug: Morphine<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain Scores on the FLACC scale | FLACC scale has been used to measure postoperative pain level in children | Twenty-four hours | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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laparotomy, levobupivacaine, patient controlled analgesia