Enhanced Recovery After Surgery Protocols in Total Knee Arthroplasty Via Midvastus Approach

Study Overview
=================
Brief Summary
-----------------
The study aimed to investigate the impact of enhanced recovery after surgery (ERAS) protocols on the clinical effect of total knee arthroplasty (TKA) via the midvastus approach

Detailed Description
-----------------
In this study, a randomized controlled study was conducted to further investigate the impact of ERAS protocols in the clinical efficacy of TKA with the midvastus approach. The ERAS protocols were adopted for the ERAS group and consisted of pure juice drinking 2 hours before the surgery, optimization of the preoperative anesthesia plan, phased use of tourniquets, and the use of tranexamic acid as well as a drug cocktail. The operative time, first postoperative walking time, first straight leg elevation time, postoperative hospitalization time, visual analogue scale score (VAS score), New York Hospital of Special Surgery knee score (HSS score), Knee Society Score (KSS score), and knee range of motion were used to assess the clinical effects in the two groups. All the included patients were followed up for 12 months.

Official Title
-----------------
Enhanced Recovery After Surgery Protocols in Total Knee Arthroplasty Via Midvastus Approach

Conditions
-----------------
ERAS, Knee Osteoarthritis

Intervention / Treatment
-----------------
* Procedure: ERAS protocols for TKA


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Unilateral primary knee osteoarthritis Varus, valgus, and flexion contracture deformity of the knee joint < 10° The range of motion of the knee joint was > 80° Body mass index (BMI) < 30 No previous history of knee surgery on the affected side .Agreed to participate in the trial. Exclusion Criteria: Rheumatoid arthritis Extra-knee deformity Simultaneous bilateral knee arthroplasty Severe dysfunction of the liver, kidney, and blood system Severe cardiovascular diseases Gastrointestinal ulcer .Other medical conditions like nausea, vomiting, snoring, and allergy to related analgesic drugs.

Ages Eligible for Study
-----------------
Minimum Age: 56 Years
Maximum Age: 74 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Common protocols for TKA<br>Common protocols for TKA | Procedure: ERAS protocols for TKA<br>* ERAS protocols for TKA<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the postoperative hospitalization time | the postoperative hospitalization time | 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the operative time | the operative time | 2 hours | 
| first postoperative walking time | first postoperative walking time | 1 day | 
| first straight leg elevation time | first straight leg elevation time | 1 day | 
| visual analogue scale score (VAS score) | VAS score (0-10 scores) is for pain: 0 represent no pain, 1-3 represent mild pain, 4-6 represent moderate pain, 7-10 represent severe pain. | 12 months | 
| New York Hospital of Special Surgery knee score (HSS score) | HSS score (0-100 scores) is for knee function: 85-100 represent excellent, 70-84 represent good, 60-69 represent fair, 0-59 represent bad. | 12 months | 
| Knee Society Score (KSS score) | KSS score (0-100 scores) is for knee function: 85-100 represent excellent, 70-84 represent good, 60-69 represent fair, 0-59 represent bad. | 12 months | 
| knee range of motion | knee range of motion | 12 months |