Gingival Depigmentation by Diode Laser

Study Overview
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Brief Summary
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Physiologic gingival pigmentation(PGP) is the most common type of gingival pigmentation and cosmetic concern particularly in gummy smile patients. Laser therapy is an effective and noninvasive treatment option. The aim of this study was to evaluate the efficacy of diod laser on the treatment of PGP in patients.

Detailed Description
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Preoperative and postoperative photographic and clinical observations about the gingival melanin pigmentation were made according to Dummett-Gupta Oral Pigmentation Index scoring criteria given by Dummett C.O. in 1964 The investigators classified pigmented gingiva in patients as: Mild:Pink to slightly brown Moderate:Deep brown or black Severe:Mixed in color Score in each tooth was taken including one full inter dental papilla. Observations were made in natural light. The assessment of the scoring of the pigmentation index were done by all the three examiners, and the agreed upon score was assigned to prevent individual variations. The investigators compared the intensity of pigmentation in each patient in recall sessions after 1month and 3mounth postoperative.

Official Title
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Efficacy of810 nm Diode Laser on Gingival Pigmentation

Conditions
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Laser-induced Hypopigmentation

Intervention / Treatment
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* Device: 810 Diode Laser


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 19 adult patients who had been referred to oral medicine department of Shahid Beheshti dental school with the chief complaint of melanin pigmentation were selected for inclusion in this study. Exclusion Criteria: Hyperpigmentation that was associated with systemic disease or drug administration,disease that could compromise wound healing (uncontrolled diabetes, autoimmune disease) Pregnancy or lactation Evidence of relationship between hyperpigmentation and malignancy History of previous treatment of hyperpigmentation Smoking Periodontal problems

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 810 Diode Laser<br>810 nm Diode Laser, contact, continuous wave,320micron, | Device: 810 Diode Laser<br>* The 810-nm diode laser has energy and wavelength characteristics that specially target the soft tissues. It has an affinity for hemoglobin and melanin, so it is an excellent soft tissue laser and is applicated for cutting and coagulating gingival tissue.Today,sparse studies have been published assessing physiologic gingival pigmentation using diode laser,therefore the aim of this study was to evaluate the effect of diode laser on the treatment of gingival pigmentation in adult patients.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| improvement of gingival pigmentation | standard digital photographs were taken preoperative,1 month after laser therapy. | 1 month | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| changes in pigmentation based on standard digital photographs and index of Dummett et al. | standard digital photographs were taken 3 months postoperative. | 3month |