Effects Of Combined Cryolipolysis And High Intensity Interval Training On Insulin Resistance And Body Composition In Polycystic Ovarian Patients

Study Overview
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Brief Summary
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this study will be carried to investigate the effect of cryolipolysis and high intensity interval training on insulin resistance and body composition in pco women

Detailed Description
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This study will be carried out on ninety females with polycystic ovarian syndrome (PCOS)l. Their age ranges from 17-28 years, body mass index 25-30 Kg/m2. They experience hyperandrogenism and hyperinsulinemia. PCOS females will be randomly assigned into three equal groups: group (A) consists of 30 women who receive cryolipolysis and group (B) consists of 30 women who receive high intensity interval training and group (C) receive both

Official Title
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Effects Of Combined Cryolipolysis And High Intensity Interval Training On Insulin Resistance And Body Composition In Polycystic Ovarian Patients

Conditions
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Polycystic Ovary Syndrome, Hyperinsulinism

Intervention / Treatment
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* Device: cryolipolysis(3 max cool shaping)
* Device: Treadmill (jkexer focus 8020A)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: women diagnosed with polycystic ovarian syndrome age ranges from 17-28 years body mass index ranges 25-30 Kg/m2 Exclusion Criteria: Diabetic patients. Women with BMI>30 Women having circulatory dysfunction. Women with respiratory or cardiac disease liver disease. Skin disease . Previous abdominal or uterine surgery any medications affecting hormones any physical impairments Physical impairment

Ages Eligible for Study
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Minimum Age: 17 Years
Maximum Age: 28 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: cryolipolysis treadmill cryolipolysis + treadmill
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: cryolipolysis<br>3max cool shaping device is administered 3 times for each patient, one session every 6 weeks, each session is 40 minutes. | Device: cryolipolysis(3 max cool shaping)<br>* cryolioplysis applied over abdomen area<br>|
| Experimental: treadmill<br>aerobic training in form of high intensity interval training, three times per week for 3 weeks by treadmill(jkexer focus 8020A) each session is for 20 minutes. | Device: Treadmill (jkexer focus 8020A)<br>* aerobic training ( high intensity interval training)<br>|
| Active Comparator: treadmill+cryolipolysis<br>aerobic training 3 times per week and cryolipolysis once every 6 weeks | Device: cryolipolysis(3 max cool shaping)<br>* cryolioplysis applied over abdomen area<br>Device: Treadmill (jkexer focus 8020A)<br>* aerobic training ( high intensity interval training)<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| HOMA IR | blood test | 3 months | 
| weight | anthropometric measure measured in kilogram (kg) | up to 3 months | 
| fat percentage | overall body fat percentage measured by body fat analyzer in percentage (%) | up to 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| waist circumference | anthropometric measurement measured in centimeter (cm) | up to 3 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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pco