Brazilian Registry for Clinical Presentation of Individuals With COVID-19 (SARS-Brazil)

Study Overview
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Brief Summary
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This is a registry-based cohort study of all adult patients (≥18 years) with confirmed or suspected SARS-CoV-2 infection. The main goal is to describe mortality incidence, demographic characteristics, coexisting conditions, treatments, outcomes among SARS-CoV2 infected patients. A secondary goal is to identify biological factors (OMICS - genomic, proteomic and metabolomics characterization) associated with severity conditions for these patients.

Detailed Description
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Registry on characteristics and outcomes of hospitalized and non-hospitalized SARS-CoV2 infected patients in Brazil.

Official Title
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Brazilian COVID-19 Registry for Clinical Presentation of Individuals With COVID-19: a National, Multicentre, Prospective Observational Study (SARS-Brazil)

Conditions
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Covid19, SARS-CoV Infection

Intervention / Treatment
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* Other: Hospital admission
* Other: Non-hospitalization procedures


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adult patients (≥18 years); Confirmed or suspected SARS-CoV2 infection Exclusion Criteria: Patient who expressed opposition to participation in the study

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Hospitalized patients<br>Patient who are suspected or confirmed SARS-CoV2 infection need hospitalization. | Other: Hospital admission<br>* Usual care.<br>|
| Non-hospitalized patients<br>Patient who are suspected or confirmed SARS-CoV2 infection non-hospitalized. | Other: Non-hospitalization procedures<br>* Usual care.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| All-cause mortality | All-cause mortality rates at 60 days | 60 Days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence and course of symptoms of COVID-19 infection | To assess the prevalence and course of symptoms of COVID-19 infection of patients followed during a period of 60 days | 60 Days | 
| Hospitalizations | Rate of patients requiring hospitalization and re-hospitalization (readmission to the hospital occurring within 60 days after admission) | 60 Days | 
| Oxygen supplementation | Rate of patients requiring oxygen therapy | 60 Days | 
| Use of invasive mechanical ventilation | Rate of patients requiring invasive mechanical ventilation | 60 Days | 
| Intensive care unit length of stay | ICU length of stay | 60 Days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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COVID-19, SARS-CoV2 infection, Intensive care unit, Oxygen supplementation, Invasive ventilation, Mortality