Oral Care to Prevent Ventilator-associated Pneumonia

Study Overview
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Brief Summary
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This study was conducted to investigate the effect of oral care given by two different methods on the development of ventilator-associated pneumonia in patients connected to mechanical ventilators.

Detailed Description
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The universe of this research, which was designed as a semi-experimental study, is composed of patients connected to the mechanical ventilator lying in Atatürk University Training and Research Hospital Anesthesia and Reanimation Intensive Care Unit between September 2019 and February 2020. A total of 57 patients, 29 method-1, 28 method-2 groups, met the inclusion criteria of the study. In the data collection phase, 'Patient Identifier Information Form', 'Patient Monitoring Form', 'Oral Assessment Scale' and 'Tracheal Aspirate Culture Result Form' were used. In the evaluation of the data, number and percentage distributions, Kruskal Wallis, Mann Withney-U, Wilcoxon Analysis, Chi-Square test were used.

Official Title
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Investigation of the Effect of Oral Care Given by Two Different Methods in Patients Connected to Mechanical Ventilators on the Development of Ventilator-AssociatedPneumonia

Conditions
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Oral Hygiene, Oral Health, Ventilators, Mechanical

Intervention / Treatment
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* Combination Product: One group received standard oral care.
* Combination Product: It was applied to the other group by aspiration.


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria:• Patients on mechanical ventilator who have been in intensive care for at least 48 hours Male and female patients over the age of 18 Patients without thrombocytopenia, leukopenia and oral stomatitis, aphthae, candiasis, gingivitis Patients whose respiratory support is provided by a mechanical ventilator Patients who are considered to be able to provide mechanical ventilator support for 7 days Patients without any respiratory-related infectious pathogens Obtaining informed consent from the patient if he/she can give consent or from his/her guardian if he/she is unable to give consent. It was determined as patients who did not undergo any intraoral surgical intervention. Exclusion Criteria: patients with pneumonia Patients younger than 18 years -

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 90 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: One group received standard oral care.<br> | Combination Product: One group received standard oral care.<br>* the effect of oral care given by two different methods on the development of ventilator-associated pneumonia in patients connected to mechanical ventilators.<br>Combination Product: It was applied to the other group by aspiration.<br>* the effect of oral care given by two different methods on the development of ventilator-associated pneumonia in patients connected to mechanical ventilators.<br>|
| Placebo Comparator: It was applied to the other group by aspiration.<br> | Combination Product: One group received standard oral care.<br>* the effect of oral care given by two different methods on the development of ventilator-associated pneumonia in patients connected to mechanical ventilators.<br>Combination Product: It was applied to the other group by aspiration.<br>* the effect of oral care given by two different methods on the development of ventilator-associated pneumonia in patients connected to mechanical ventilators.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| oral care application with standard oral care stick | Administered with chlorhexidine gluconate solution. | 1 in 6 hours | 
| Oral care application with a sucking oral care stick | Administered with chlorhexidine gluconate solution. | 1 in 6 hours | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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nursing, Mechanical ventilation, oral care, pneumonia