The Influences Of Anterior Capsule Polishing On Anterior Capsular Changes and Intraocular Lenses Stability of Super High Myopic Eyes

Study Overview
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Brief Summary
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A prospective study included 20 patients with super high myopia who underwent bilateral uneventful cataract. 360°anterior capsule polishing was performed with double-ended capsule polisher randomly in one eye, and the opposite unpolished was used as the control. The refractive state and size of anterior opening were measured at postoperative 1 day as the baseline. Then they followed up at 1 month, 3 months and 6 months after surgery to record refractive state, higher-order aberrations, size of anterior opening, tilt and decentration of IOL (intraocular lenses)and PAD(postoperative aqueous depth). The paired t test was used to compare the differences between the two groups, and the same test the postoperative follow-up comparing with the baseline.

Official Title
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The Influences of 360° Anterior Capsule Polishing on Refraction, Anterior Capsular Opening Size and IOL Stability Among Super High Myopia Patients

Conditions
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Myopia, High, With Cataract and Anterior Capsule Polished

Intervention / Treatment
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* Procedure: 360°anterior capsule polishing


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria:cataract patients with super high myopia (axial length >27mm) and difference of binocular was less than 1mm Exclusion Criteria:larger corneal astigmatism need toric intraocular lens; patients with any systemic or ocular diseases that may influence the anterior capsule opening morphologic, such as keratonosus, glaucoma, uveitis, Pseudoexfoliation syndrome, retinitis pigmentosa and diabetes and Myotonic Dystrophy, etc.; patients with ophthalmic surgery and trauma history.

Ages Eligible for Study
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Minimum Age: 50 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: polished group<br>360°anterior capsule polishing was performed with double-ended capsule polisher randomly in one eye | Procedure: 360°anterior capsule polishing<br>* 360°anterior capsule polishing was performed with double-ended capsule polisher<br>|
| Placebo Comparator: unpolished group<br>the opposite unpolished was used as the control | Procedure: 360°anterior capsule polishing<br>* 360°anterior capsule polishing was performed with double-ended capsule polisher<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| refraction | refractive state | Change from postoperative 1 day to 1 months | 
| anterior opening size | area,diameter | Change from postoperative 1 day to 1 months | 
| Stability of IOL | Tilt and Decentration | Change from postoperative 1 months to 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| refraction | refractive state | Change from postoperative 1 month to 3 months | 
| refraction | refractive state | Change from postoperative 3 month to 6 months | 
| anterior opening size | area,diameter | Change from postoperative 1 month to 3 months | 
| anterior opening size | area,diameter | Change from postoperative 3 month to 6 months | 
| Stability of IOL | Tilt and Decentration | Change from postoperative 3 month to 6 months |