Survival of Endocrowns Made From Different Ceramics

Study Overview
=================
Brief Summary
-----------------
Restoration of endodontically treated teeth requires a means to protect the cusps from the wedging forces of occlusion. When there is extensive loss of tooth structure, cuspal coverage is warranted. Usually this is in the form of indirect restoration. Traditionally, full coverage crowns have been used which would require further removal of sound tooth structure. Recently, adhesive alternatives have been introduced which allow for conservation of tooth structure. Different materials can be used for this purpose. The evidence on the long-term survival of these materials is scarce. This study aims to investigate the short and medium-long term survival rate of these prostheses.

Official Title
-----------------
The Endocrown; a Prospective Randomised Clinical Trial of Three Different Ceramics

Conditions
-----------------
Pulp Disease, Dental, Dental Caries, Dental Leakage

Intervention / Treatment
-----------------
* Device: Dental prosthesis
* Device: Dental crown
* Device: Hybrid ceramic


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Root canal treated molars with significant loss of tooth structure Supra-gingival margins Teeth scheduled for cuspal-covering indirect restorations Exclusion Criteria: Teeth with extensive cracks or fractures Teeth with deep subgingival margins Non-functional teeth (no opposing dentition) Teeth with advanced periodontitis

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Three different ceramic types for restoration of endodontically treated teeth
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Lithium disilicate<br>Lithium disilicate: a type of ceramic material used to make a dental prosthesis that replaces missing tooth structure following root canal treatment. Other names might include: E-max crowns, computer-aided design and computer-aided manufacturing (CAD CAM) crowns | Device: Dental prosthesis<br>* Replacement of missing tooth structure using Lithium disilicate porcelain<br>* Other names: Crowns;|
| Active Comparator: Monolithic zirconia<br>Monolithic zirconia: a type of ceramic material used to make a dental prosthesis that replaces the missing tooth structure following root canal treatment. Other names might include: Zolid crown, Bruxzir, Bretau, CAD CAM crowns | Device: Dental crown<br>* Replacement og missing tooth structure using monolithic zirconia<br>* Other names: Endocrown;|
| Active Comparator: Hybrid ceramic<br>Hybrid ceramic: a type of ceramic material used to make a dental prosthesis that replaces the missing tooth structure following root canal treatment. Other names might include: Enamec, Lava Ultimate, CAD CAM crowns | Device: Hybrid ceramic<br>* Restroration of endodontically treated teeth using hybrid ceramic<br>* Other names: Indirect restoration;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Survival of Dental Prosthesis | The endocrowns (the dental prosthesis studied) were assessed after 24 months. Those that were functional and without any symptoms were considered surviving. | 24 months |