Dietary Supplements and Exercise in Aging Adults

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to determine the effects of food supplements and strength training on appetite, the amount of energy used, and body composition.

Conditions
-----------------
Exercise

Intervention / Treatment
-----------------
* Other: Dietary supplements with exercise
* Dietary Supplement: Dietary supplement without exercise


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Adults age 55 and older Body mass index 20 to ≤35 kg/m2 Weight stable (<4kg change within the last 3 months) Constant habitual activity patterns (no deviation > 1x/wk of 30 min/session within last 3 months) Clinically normal blood and urine profiles as determined by our study physician Not taking medications known to influence appetite nor any anti-inflammatory steroid medications No hip replacements Exclusion Criteria: Adults with medical conditions that might place them at risk for participating in the study or interfere with the successful completion of the study protocol will be excluded

Ages Eligible for Study
-----------------
Minimum Age: 55 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 1<br>Solid dietary supplements with exercise | Other: Dietary supplements with exercise<br>* Resistive exercise along with consuming two dietary supplements every day during both 8 week intervention periods, for a total of 16 weeks.<br>|
| Experimental: 2<br>Solid dietary supplements without exercise | Dietary Supplement: Dietary supplement without exercise<br>* Consuming two dietary supplements every day during both 8 week intervention periods, for a total of 16 weeks.<br>|
| Experimental: 3<br>Liquid dietary supplements with exercise | Other: Dietary supplements with exercise<br>* Resistive exercise along with consuming two dietary supplements every day during both 8 week intervention periods, for a total of 16 weeks.<br>|
| Experimental: 4<br>Liquid supplements without exercise | Dietary Supplement: Dietary supplement without exercise<br>* Consuming two dietary supplements every day during both 8 week intervention periods, for a total of 16 weeks.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Appetite questionnaire, urine collection, strength testing, body composition, resting metabolic rate, food records, breath sample, activity assessments, dietary supplements, nightly logs, and resistive exercise. |  | 23 weeks | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
The study is designed to determine the effects of food supplements and strength training.