linjc16/ctgov huggingface dataset:
Memory for Health Research Findings

Study Overview
=================
Brief Summary
-----------------
This experiment tests young (ages 18-35) and older adult (ages 60-80) participants. Participants will watch a brief video, will complete a memory task, and will complete measures about their beliefs.

Detailed Description
-----------------
Participants (360 young adults and 360 older adults) will complete a baseline beliefs measure and will then be randomly assigned to one of two study conditions. They will watch a 2.5-min video that presents research findings related to their health. Their memory for the video will be tested, and participants will also complete a demographic questionnaire and another survey about their beliefs. Participation will last 15-20 minutes.

Official Title
-----------------
Memory for Health Research Findings

Conditions
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Healthy Aging

Intervention / Treatment
-----------------
* Behavioral: Video type


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 18 to 35 years old or 60 to 80 years old Fluent English speakers Exclusion Criteria: -

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Factorial Assignment
Interventional Model Description: Participants from two age groups (young vs. older adults) will be compared for two experimental conditions. Although age group cannot be randomly assigned, the comparison between groups makes the design factorial.
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: First health video<br>This video presents health information for one study condition. | Behavioral: Video type<br>* One of two videos presenting health research findings (each 2.5 minutes in length) will be shown to a participant.<br>|
| Active Comparator: Second health video<br>This video presents health information for one study condition. | Behavioral: Video type<br>* One of two videos presenting health research findings (each 2.5 minutes in length) will be shown to a participant.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Health Beliefs | A survey about the participant's beliefs | 3 minutes |
Vascular and Neurologic Exploration of Small Nervous Fiber by Sudoscanner and QST

Study Overview
=================
Brief Summary
-----------------
Erythromelalgy (EM) is a vascular syndrome very rare affecting the feet. This disease evolve by crisis when the feet extremities become red hot and painful. There are several types of EM but this study concern the adult primitive form. For a long time, the physiopathology was not described but now we know that there is a vascular form, with microcirculatory dysfunction and a neurologic form with small fibers neuropathy. The diagnostic of neurologic form is based on clinical evaluation (DN4 questionnaire, UENS scale...) and an electromyography. Thermotest, a medical device which measure the thermic sensitivity is used to quantify neuropathy. More recently Sudoscan, a device measuring cutaneous impedance to chloride ions detect small nervous fiber in diabetic patients with good correlation with Thermotest. The purpose of this study is to analyze the vascular side and the neurologic side on patients consulting for Erythromelalgy.

Official Title
-----------------
Vascular and Neurologic Exploration of Small Nervous Fiber by Sudoscanner

Conditions
-----------------
Erythermalgia

Intervention / Treatment
-----------------
* Other: impedance measurement and pain evaluation


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Pain with burn feeling at hands and feet extremities Crisis activated by the heat Age > 18 years old Exclusion Criteria: Patients who had burn in extremities

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Other
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: erythermalgia patient<br>patient will be measured chlorine ions impedance with the SUDOSCAN and evaluation on pain du to temperature with the THERMOTEST | Other: impedance measurement and pain evaluation<br>* Measurement of chlorine ions impedance by SUDOSCAN and pain due to temperature evaluation with THERMOTEST<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Assessment of Chlorine ion production change | patient will be measured the impedance of chlorinates ions by Sudoscan | Day1 | 
| Assessment of Temperature changing sensitivity | Patients will be measured their sensitivity to temperature changing using the Thermotest | Day1 |
Interest of the Manual Exploration as a Supplement to the Coelioscopy in the Evaluation of the Resectability of Peritoneal Carcinosis

Study Overview
=================
Brief Summary
-----------------
This is a Multicenter prospective diagnostic study.

Conditions
-----------------
Ovarian Cancer With Peritoneal Carcinosis

Intervention / Treatment
-----------------
* Procedure: GelPort
* Procedure: laparotomy


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Over 18 years of age Patient Woman presenting a peritoneal carcinosis presumed ovarian origin Coelioscopy (1st intent or recurrence) planned or performed in the last 4 weeks for laparotomy. The peritoneal cancer index of Sugarbaker must be available. WHO 0 - 2 Membership in a social security system Patient having given her written consent Exclusion Criteria: Male Contraindication in the coelioscopy Any associated medical or psychological condition which could compromise the capacity of the patient to participate in the study Patient deprived of freedom, under guardianship or guardianship

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: manual exploration by GelPort<br>manual exploration in supplement of coelioscopy before laparotomy | Procedure: GelPort<br>* Manual exploration of the peritoneal carcinosis by the system GelPort ® with calculation of peritoneal cancer index for evaluation of the resectability<br>Procedure: laparotomy<br>* laparotomy will be performed if indication confirmed by manual exploration<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| evaluate the number of patients with or without laparotomy after evaluation of the resectability by coelioscopy and coelioscopy more manual exploration |  | 1 month after inclusion | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of patients with complications (eventrations, infections, pains) after manual exploration |  | 1 month after inclusion | 
| Number of patients with parietal metastases |  | 1 month after inclusion | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
ovarian cancer, peritoneal carcinosis, manual exploration, surgery, GelPort
Phosphodiesterase Inhibitors, Pentoxifylline, as Adjunctive Therapy in Patients With Ulcerative Colitis.

Study Overview
=================
Brief Summary
-----------------
Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disease characterized by diffused inflammation of the colon and rectum mucosa; however, the exact underlying mechanisms of UC remain poorly understood. Also, it is associated with high risk of colon cancer, so there is a continuous need for introducing new therapies that decrease progression, and hence better outcomes

Official Title
-----------------
Phosphodiesterase Inhibitors, Pentoxifylline, as Adjunctive Therapy in Patients With Ulcerative Colitis.

Conditions
-----------------
Inflammatory Bowel Diseases

Intervention / Treatment
-----------------
* Drug: Pentoxifylline 400 MG


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age ≥ 18 years Both males and females will be included Negative pregnancy test and effective contraception. Exclusion Criteria: Breastfeeding Significant liver and kidney function abnormalities Colorectal cancer patients Patients with severe UC Patients taking rectal or systemic steroids Patients taking immunosuppressives or biological therapies Addiction to alcohol and / or drugs

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: Control Group<br>Mesalamine group, who will receive 1 g mesalamine three times daily for 6 months. | |
| Active Comparator: Pentoxifylline group<br>The pentoxifylline group will receive 1 g mesalamine three times daily plus pentoxifylline 400 mg two times daily for 6 months. | Drug: Pentoxifylline 400 MG<br>* Pentoxifylline (PTX) is a methyl-xanthine derivative that possesses antioxidant and anti-inflammatory characteristics<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| changes in Mayo Score Index. | The Mayo Score for ulcerative colitis disease activity assesses disease severity and can be used to monitor patients during therapy. This scale uses four parameters to calculate the patient scores from 0-12. The parameters assessed are rectal bleeding, stool frequency, endoscopic findings, and physician assessment. Higher scores mean poor progression. Lower scores mean good progression | 6 months |
Non-invasive Nerve Stimulation and Cognitive Training to Improve Cognitive Performance in Healthy Older Adults

Study Overview
=================
Brief Summary
-----------------
We need better tools to both enhance brain health and improve cognitive performance in healthy brain aging so that it can be delayed, reduced, or even reversed. The present proposal is designed to evaluate the pairing of cognitive training with a non-invasive neurostimulation technology that has shown promise in both increasing neuroplasticity and in enhancing cognitive performance, transcutaneous vagal nerve stimulation (tVNS).

Official Title
-----------------
Non-invasive Nerve Stimulation and Cognitive Training to Improve Cognitive Performance in Healthy Older Adults

Conditions
-----------------
Aging

Intervention / Treatment
-----------------
* Device: Transcutaneous vagal nerve stimulation (tVNS)
* Behavioral: cognitive training


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Healthy individuals willing to commit to study requirements Exclusion Criteria: Neurological disorders to include traumatic brain injury. Evidence of dementia . Major psychiatric illness Unstable and chronic medical conditions. MRI contraindications (e.g., pregnancy, claustrophobia, metal implants that are contraindicated for MRI). Physical impairment precluding motor response or lying still or walking Hearing or vision deficits that will not allow for completion of assessments

Ages Eligible for Study
-----------------
Minimum Age: 65 Years
Maximum Age: 90 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: tVNS group<br>Participants will undergo cognitive training with tVNS | Device: Transcutaneous vagal nerve stimulation (tVNS)<br>* a non-invasive and safe technique that transiently enhances brain GABA and noradrenaline levels.<br>Behavioral: cognitive training<br>* A program of regular mental activities purported to maintain or improve one's cognitive abilities.<br>|
| Sham Comparator: Sham group<br>Participants will undergo cognitive training with earlobe sham | Behavioral: cognitive training<br>* A program of regular mental activities purported to maintain or improve one's cognitive abilities.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in working memory and processing speed contributors | The Posit Science BrainHQ | Baseline to 2 weeks |
Illinois WISEWOMAN Project

Study Overview
=================
Brief Summary
-----------------
To provide low-income, under- or uninsured 40- to 64-year-old women with the knowledge, skills, and opportunities to improve diet, physical activity, and other lifestyle behaviors to prevent, delay and control cardiovascular and other chronic diseases.

Official Title
-----------------
Illinois WISEWOMAN Project

Conditions
-----------------
CVD Risk

Intervention / Treatment
-----------------
* Behavioral: Women's health


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: NBCCEDP Exclusion Criteria: -

Ages Eligible for Study
-----------------
Minimum Age: 40 Years
Maximum Age: 64 Years

Sexes Eligible for Study
-----------------
Female

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: Women's health|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
Retinal Redetachment After Silicone Oil Removal : a Risk Factor Analysis

Study Overview
=================
Brief Summary
-----------------
To report the rate of retinal redetachment after silicone oil removal (SOR) following rhegmatogenous retinal detachment (RRD) surgery and to determine potential risk factors

Official Title
-----------------
Retinal Redetachment After Silicone Oil Removal : a Risk Factor Analysis

Conditions
-----------------
Retinal Redetachment After Silicone Oil Removal

Intervention / Treatment
-----------------
* Other: no intervention


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients with successfully repaired rhegmatogenous retinal detachment and subsequent silicone oil removal minimum follow-up period of 6 months after silicone oil removal Exclusion Criteria: Silicone oil tamponade for indications other than rhegmatogenous retinal detachment Retinal redetachment during silicone oil tamponade Prior history of silicone oil tamponade
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| retinal redetachment after silicone oil removal<br> | Other: no intervention<br>* no intervention<br>|
| NO retinal redetachment after silicone oil removal<br> | Other: no intervention<br>* no intervention<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| rate of retinal redetachment after silicone oil removal |  | a minimum period of 6 months after silicone oil removal | 
| pre- and intraoperative risk factors of retinal redetachment after silicone oil removal |  | a minimum period of 6 months after silicone oil removal | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| final retinal reattachment rate |  | a minimum period of 6 months after silicone oil removal | 
| final best corrected visual acuity |  | a minimum period of 6 months after silicone oil removal | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
rhegmatogenous retinal detachment, silicone oil, proliferative vitreoretinopathy
Childhood Obesity Prevention

Study Overview
=================
Brief Summary
-----------------
To develop and evaluate a culturally appropriate childhood obesity prevention program targeting primary care-givers of third grade students. The cognitive-behavioral lifestyle intervention consisted of eight, 90-minute sessions at the elementary schools. Primary outcome: body mass index of third graders and their primary care-givers Primary objective: To engage primary care-givers of third grand children in identifying and creating health promoting culturally appropriate environments for young children.

Detailed Description
-----------------
The sessions include information about energy balance, portion control, appropriate amounts and types of physical activity, physical inactivity, nutrition and self-esteem. The influence of the primary care-giver on the children's physical activity and nutritional behaviors may lead to greater or lesser rates of obesity in childhood and eventually lead to adult obesity. Therefore, the intention of this intervention is to educate primary care-givers so as to effect change (in a positive way) in the children they care for. Assessment on steps taken, BMI, percent body fat, diet, self reported physical activity and diet will be used to evaluate the impact of the sessions.

Official Title
-----------------
Project FAMILIA Giya Marianas: Childhood Obesity Prevention Program

Conditions
-----------------
Childhood Obesity, Diabetes

Intervention / Treatment
-----------------
* Behavioral: Diet, Physical activity, Physical inactivity


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Currently having a third grader attending public school Exclusion Criteria: None
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: Diet, Physical activity, Physical inactivity|Community based participatory research design|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Body Mass Index |  | 3 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| steps |  | 3 years | 
| Percent body fat |  | 3 years | 
| Basal metabolic rate |  | 3 years | 
| Diet information (child and primary care-giver) |  | 3 years | 
| Physical Activity and Inactivity information (child and primary care-giver) |  | 3 years | 
| Self esteem measures |  | 3 years | 
| Knowledge and attitudes |  | 3 years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Obesity, Prevention, Childhood, Children, Primary care-giver
Sonographic and Laboratory Evaluation of the Thyroid Gland in Patients With Systemic Sclerosis

Study Overview
=================
Brief Summary
-----------------
Systemic sclerosis (SSc) is a systemic disease that involves various organs such as the skin, kidneys, gastrointestinal tract and lungs. Dysfunction of the thyroid gland is prevalent in these patients and may be related to thyroid fibrosis or to thyroid autoimmune disease, i.e. hashimoto's thyroiditis. Thyroid nodules are prevalent in the general population, although some reports suggest they might be more frequent in patients with SSc. Hashimoto's thyroiditis, by itself, carries a higher risk for thyroid nodules and thyroid cancer. The aim of the study:To characterize sonographycally the thyroid gland of patients with SSc with and without Hashimoto's disease

Detailed Description
-----------------
The study protocol Fifty patients with SSc according to the current international classification will be included in the study. The patients, followed-up regularly in an out-patient clinic, will be tested for their thyroid function tests as well as the presence of thyroid auto antibodies. Clinical data will be collected from their medical records. Ultrasonographic examination of the thyroid gland will be performed by a single examiner. The gland will be characterized in detail with regards to its size and echotexture and cervical lymph nodes will be detected. The number and size of its nodules will be described as well as their echoic pattern (iso, hyperechoic or hypoechoic) calcifications (micro and macro), and borders status. Large nodules (≥ 1 cm in diameter) or with malignancy- associated characteristics will be aspirated according to current clinical practice. Treatment will be given according to the cytology diagnosis. Thyroid hormone supplementation will be recommended when thyrotropin level >8 mIU/L or according to clinical judgment of the investigators.

Official Title
-----------------
Sonographic Characterization of the Thyroid Gland in Patients With Systemic Sclerosis With and Without Hashimoto Thyroiditis

Conditions
-----------------
Systemic Sclerosis, Hashimoto Thyroiditis, Thyroid Nodules

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Clinical diagnosis of systemic sclerosis Exclusion Criteria: non

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| There are no spesific outcome measures from trail | the measures from trail are equal to vast population | Nnone | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
systemic sclerosis, hashimoto thyroiditis, thyroid nodules