Motivational Interviewing and Guided Opioid Tapering Support to Promote Postoperative Opioid Cessation

Study Overview
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Brief Summary
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The purpose of this study is to evaluate the relative efficacy of enhanced usual care versus motivational interviewing and guided opioid tapering support to promote opioid cessation after total hip or knee replacement surgery.

Official Title
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Randomized Controlled Trial to Evaluate the Relative Efficacy of Motivational Interviewing and Guided Opioid Tapering Support vs. Enhanced Usual Care to Promote Opioid Cessation After Orthopedic Surgery

Conditions
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Opioid Cessation

Intervention / Treatment
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* Behavioral: Motivational Interviewing and Guided Opioid Tapering Support
* Behavioral: Enhanced Usual Care


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Planning to undergo surgery English speaking Ability and willingness to complete questionnaires and assessments Scheduled for total hip, knee, or shoulder replacement Preoperative opioid use and opioid use 14 days after surgery to increase the likelihood of delayed opioid cessation. Not under the care of a current pain management provider Exclusion Criteria: Any conditions causing inability to complete assessments Known pregnancy Elevated suicidality Enrollment in conflicting perioperative trial

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Motivational Interviewing and Guided Opioid Tapering Support<br> | Behavioral: Motivational Interviewing and Guided Opioid Tapering Support<br>* Following surgery, participants will undergo motivational interviewing with a trained member of the study staff. These calls will occur weekly for 6 weeks with a follow-up call at 10 weeks or until the participant completes the protocol.<br>|
| Experimental: Enhanced Usual Care<br> | Behavioral: Enhanced Usual Care<br>* Following surgery, participants will receive phone calls from a trained member of the study staff to discuss various aspects of surgical recovery and medication use. These calls will occur weekly for 6 weeks with a follow-up call at 10 weeks or until the participant completes the protocol.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Time to Opioid Cessation | Time to opioid cessation between the two groups will be analyzed using survival analysis | Through study completion, an average of 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Opioid Misuse | Participant score on the Current Opioid Misuse Measure and prescription information obtained via CURES 2.0 will be used to assess opioid misuse behaviors. | Through study completion, an average of 1 year |