Transverse Abdominis Plane Block in Laparoscopic Ventral Hernia Repair

Study Overview
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Brief Summary
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The current study aims to determine if transverse abdominis plane block using local anesthetic agents (bupivacaine 0.25% + Ropivacaine 0.20%) decreases the post operative pain and helps in early mobilization or discharge from hospital in patients undergoing laparoscopic ventral hernia repair.

Detailed Description
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Patients meeting inclusion criteria would be randomised after admission. Those patients in experimental arm shall receive the TAP block under USG guidance while those in control arm do not receive any block. Surgery shall be proceeded in the usual manner in all the patients and assessment for pain starts in the immediate post operative or recovery room after the patient is completely conscious. The total amount of analgesic required by the patient is measured. Pain assessment is done using the visual analog scale (VAS) at regular intervals until follow up review.

Official Title
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Randomized Clinical Trial: Transverse Abdominis Plane Block Versus no Block in Laparoscopic Ventral Hernia Repair

Conditions
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Ventral Hernia

Intervention / Treatment
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* Procedure: Laparoscopic ventral hernia repair with TAP block
* Procedure: Laparoscopic ventral hernia repair without TAP block


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All patients undergoing laparoscopic ventral hernia repair during the study period Exclusion Criteria: Age <15 or greater than 75 years ASA > 3 Obstructed , recurrent or strangulated hernia Lap assisted open hernia repair Patients undergoing component separation Parastomal hernia, spigelian hernia, lumbar hernia Patients with Chronic kidney disease, bronchial asthma Patients allergic to bupivacaine or NSAIDs Not willing to participate

Ages Eligible for Study
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Minimum Age: 15 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Prospective double blinded balanced allocation, randomized clinical trial
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: TAP block<br>Patients undergoing laparoscopic ventral hernia repair with TAP block with 0.2% ropivacaine under ultrasound guidance | Procedure: Laparoscopic ventral hernia repair with TAP block<br>* Transverse abdominis plane block is given under ultrasound guidance during laparoscopic ventral hernia surgery<br>* Other names: Bupivacaine 0.25% and Ropivacaine 0.2% subcutaneous injection;|
| Active Comparator: No TAP block<br>Patients undergoing laparoscopic ventral hernia repair without TAP block | Procedure: Laparoscopic ventral hernia repair without TAP block<br>* No block administered during Laparoscopic ventral hernia surgery<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Post operative cumulative analgesic requirement | The amount of analgesic required by the patient during hospital stay | 24 hours after surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Post-operative hospital stay | The time taken to get discharged from the hospital | 7 days from primary surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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TAP block, laparoscopic IPOM, post operative pain