Perception of Cure Among Patients With Metastatic Cancer

Study Overview
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Brief Summary
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This study collects information about perception of cure among patients with cancer that has spread to other places in the body (metastatic). This study aims to determine patients' perception (knowledge) before starting immunotherapy and if differences exist in understanding of treatment to stimulate or restore the ability of the body's immune (defense) system to fight infection and disease (immunotherapy) based on social and economic factors or on race/ethnicity.

Detailed Description
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PRIMARY OBJECTIVE: I. To assess the proportion of patients with metastatic cancer who anticipate cure before starting immunotherapy. SECONDARY OBJECTIVES: I. To determine if expectations of cure are associated with quality of life and distress. II. To determine if patients' perceptions differ by gender, age, and ethnicity. OUTLINE: Patients complete surveys over 30 minutes about sociodemographic information and perception of immunotherapy, over 10 minutes about expectations of cure, over 10 minutes about anxiety, over 10 minutes about depression, and over 30 minutes about physical well-being. Patients' medical records are reviewed.

Official Title
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The Perception of Cure Among Patients With Metastatic Cancer

Conditions
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Hematopoietic and Lymphoid Cell Neoplasm, Metastatic Malignant Solid Neoplasm

Intervention / Treatment
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* Other: Electronic Medical Record
* Other: Survey Administration


Participation Criteria
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Eligibility Criteria
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Eligibility Criteria: Patients must be aged 18 and over Patients sufficiently fluent in English Patients must have a cytologically or pathologically verified diagnosis of cancer Patients must have measurable metastatic disease Patients must be initiating immunotherapy Patients must be undergoing evaluation and treatment at City of Hope Cancer Center

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Observational (survey, medical records review)<br>Patients complete surveys over 30 minutes about sociodemographic information and perception of immunotherapy, over 10 minutes about expectations of cure, over 10 minutes about anxiety, over 10 minutes about depression, and over 30 minutes about physical well-being. Patients' medical records are reviewed. | Other: Electronic Medical Record<br>* Medical records are reviewed<br>* Other names: EMR (electronic medical record);Other: Survey Administration<br>* Complete surveys<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Percentage of patients | Will assess the percentage of patients who anticipate cure before starting immunotherapy, scoring a '1' on the Perception of cure tool, and anticipate >75% chance for a cure. | Up to 2 years | 
| Patient Reported Outcomes Measurement Information System (PROMIS) | Descriptive analyses (e.g. frequency statistics) will be used to characterize the sample and to look at the association between Patient Reported Outcomes Measurement Information System (PROMIS) tool score with perception of cure score. | Up to 2 years | 
| Functional Assessment of Cancer Therapy-General (FACT-G) | Descriptive analyses (e.g. frequency statistics) will be used to characterize the sample and to look at the association between Functional Assessment of Cancer Therapy-General (FACT-G) overall score with perception of cure score. | Up to 2 years | 
| Perceptions of cure | Chi-square analyses will be used to examine perceptions of cure by sociodemographic characteristics: gender (male and female), age (< 60 and > 60), and ethnicity (white non-Hispanic, Hispanic, and other). | Up to 2 years |