Exercise and Activity Guidance in Older Adults With Diabetes

Study Overview
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Brief Summary
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The purpose of the project is to better understand how exercise and education will help mobility and health in older adults with diabetes. The investigators are trying to learn what type of exercises and classes are needed to help older adults stay active. This knowledge will eventually prove useful in helping patients and doctors understand what is needed to keep older adults with Type 2 diabetes as healthy as possible.

Detailed Description
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Information and health screening: Interested persons are screened for eligibility and undergo a directed medical history and examination, echocardiogram (if not done within one year), limited ABI test, and maximal treadmill test with oxygen kinetics. Measure fitness level at the beginning of the exercise training, at 10 and 20 weeks: DEXA scan, body fat analysis, strength and balance measurements, and blood tests. Train for 10 weeks in a supervised small group format. Classes meet three times a week for an hour. Participants are randomly assigned to: 1) Flexibility and toning exercises + health education, or 2) Functional circuit training + home activities + tailored physical activity guidance. 4. Follow-up phone calls for an additional 10 weeks.

Official Title
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Aerobic Performance,Mobility Limitations and Exercise in Older Adults With Diabetes

Conditions
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Type 2 Diabetes

Intervention / Treatment
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* Behavioral: Functional circuit training with lifestyle behavior


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: History of type 2 diabetes on medications Age 60 or older Able to attend local class 3 times per week for 10 weeks Exclusion Criteria: Ejection fraction <40% Symptomatic obstructive valvular disease (primarily aortic stenosis) Atrial fibrillation with poor rate control (particularly during exercise), or high grade AV block Substantial dementia (Folstein Mini Mental State Examination <24 out of 30) Blood tests suggesting severe renal (Cr>3.0) or hepatic (transaminases>4x normal) disease Alcohol intake >3 oz/day Hemiplegia or lower limb amputation Participating in regular exercise 2 or more hours per week. Significant orthopedic or musculoskeletal condition that limits weight bearing Acute medical conditions, such as acute flare-up of joint condition or infection Normal FBS in those with equivocal diabetes history (< 130)

Ages Eligible for Study
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Minimum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: Functional circuit training with lifestyle behavior|nan|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Functional mobility performance |  |  | 
| Physical activity |  |  | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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type 2 diabetes, exercise, activity guidance, health education