Investigation of the Effect of Stair Activity on Lumbal Paravertebral Mechanical Properties in Amputes.

Study Overview
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Brief Summary
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With the onset of prosthesis use following lower extremity amputations,body shows biomechanical changes according to the amputation level and consequently develops adaptation mechanisms both on the healthy and ampute side. Adaptations in the lumbo-pelvic and lower lumbar regions cause asymmetries in the muscle tissue by causing changes in the morphological structure of the muscle, especially in the muscles of the waist, hip and knee and recruitment. The aim of this study is to investigate the effect of stairing up and down activity on the mechanical properties of lumbal paravertebral muscles in TFA and TTA and its relation with lower lumbar region pain.

Official Title
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Investigation of the Effect of Stair Activity on Lumbal Paravertebral Mechanical Properties in Transtibial and Transfemoral Amputes.

Conditions
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Stair up and Down, Amputation, Amputation,Stair up and Down

Intervention / Treatment
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* Other: Group 1
* Other: Group 2


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: to be TTA and TFA No complaints of chronic low back pain before amputation Using prosthesis for at least 6 months Being able to climb up and down stairs No history of falls that will cause injury or pain in the past 6 months Having good prosthesis comfort BMI<28.5 Who can have cognitive functions to understand Arabic language Exclusion Criteria: To be amputated due to congenital and tumor Who can not have cognitive functions to understand Arabic language Having orthopedic or neurological disorders that may cause chronic pain or functional impairment in the lumbar region Ankylosing spondolitis and rheumatoid arthritis patients

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 55 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Group 1<br>Transtibial amputation The patients will be asked to go up and down 9-step stair with the highest speed they can make. | Other: Group 1<br>* The patients will be asked to go up and down 9-step stair with the highest speed they can make.<br>|
| Group 2<br>Transfemoral amputation The patients will be asked to go up and down 9-step stair with the highest speed they can make. | Other: Group 2<br>* The patients will be asked to go up and down 9-step stair with the highest speed they can make.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluation of the mechanical properties of the muscle-1 | Viscoelastic stiffness [N/m] will be measured in MyotonPro 3 (MYO, Tallin, Estonia | Change from Baseline mechanical properties at following staring up and down activity, at 10 minutes after the staring up and down activity | 
| Evaluation of the mechanical properties of the muscle-2 | Oscillation frequency (Hz) will be measured in MyotonPro 3 (MYO, Tallin, Estonia | Change from Baseline mechanical properties at following staring up and down activity, at 10 minutes after the staring up and down activity | 
| Evaluation of the mechanical properties of the muscle-3 | Mechanical stiffness (N/m) will be measured in MyotonPro 3 (MYO, Tallin, Estonia | Change from Baseline mechanical properties at following staring up and down activity, at 10 minutes after the staring up and down activity | 
| Evaluation of the back pain | Pain will be evaluated by using Visual analog scale ranging 0 (no pain)- 10 (worst pain) | Change from Baseline mechanical properties at following staring up and down activity, at 10 minutes after the staring up and down activity | 
| Evaluation of the pressure-pain threshold | The pressure-pain threshold (lbs) will be measured in algometer commander (JTECH MEDICAL, MM036_K, 2016) | Change from Baseline mechanical properties at following staring up and down activity, at 10 minutes after the staring up and down activity |