LPP , MP and DP:Relation With Mortality and SOFA in Mechanically Ventilated Patients in ER, Ward and ICU

Study Overview
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Brief Summary
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Prospective, observational, longitudinal study, September 2019 to March 2020 of all adult patients who required invasive mechanical ventilation treated at General Hospital of Zone 11 IMSS in Piedras Negras, Coahuila. The investigators aim to assess the relation of lung protective ventilation, mechanical power and driving pressure in mortality and SOFA of mechanically ventilated patients inside and outside ICU at the General Hospital of Zona 11 Piedras Negras, IMSS

Detailed Description
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Prospective, observational, longitudinal study from Sept 2019 to Feb 2020 of all adult patients who required invasive mechanical ventilation treated at General Hospital of Zone 11 IMSS in Piedras Negras Coahuila. Independent variable: Lung protective ventilation, Mechanical power, Driving pressure Dependent variable: Hospital Mortality, Sequential Organic Failure Assessment (SOFA) Also will be registered: Primary diagnosis Compliance with lung protective ventilation Complications associated to mechanical ventilation Quality of attention indicators for MV patients as defined by Semicyuc. Real mortality vs Expected mortality analysis

Official Title
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Relation of Pulmonary Protective Ventilation, Mechanical Power and Driving Pressure With Mortality and SOFA of Mechanically Ventilated Patients in ER, Ward and ICU at General Hospital 11 IMSS Piedras Negras, Coahuila

Conditions
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Mechanical Ventilation Complication, Mechanical Power, Driving Pressure, Lung Protective Ventilation

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients with 18 years or older, with invasive mechanical ventilation Exclusion Criteria: Patients with 17 years or younger

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Correlation of Lung protective ventilation with mortality and SOFA (Sequential Organic Failure Assessment) | Lung Protective Ventilation: Qualitative variable will be defined as YES or NO with the averages of the daily measurements of tidal volume and Pressure plateau. It is defined as Tidal volume (Vc or Vt) <8 ml / kg (ideal weight) and Plateau or plateau pressure (Ppl, Pm) <30cmH2O | Sept 19-Feb 20 | 
| Correlation of mechanical power with mortality and SOFA | Mechanical power: Quantitative variable. calculated using Marinni equation: MP= (0.098)x(Plateau pressure-PEEP)x Respiratory Rate xTidal Volume. Normal range < 13 | Sept 19-Feb 20 | 
| Correlation of driving pressure with mortality and SOFA | Driving Pressure: Quantitative variabel, calculated using: Pplateau pressure-PEEP. nomral range < 13 | Sept 19-Feb 20 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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lung protective ventilation, mechanical power, driving pressure, SOFA