Collection of Information to Better Understand Young Onset Colorectal Cancer

Study Overview
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Brief Summary
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The purpose of this registry study is to create a database-a collection of information-for better understanding young onset colorectal cancer. Colorectal cancer patients are considered to have young onset colorectal cancer if they are diagnosed with their cancer before the age of 50. Researchers will use the information from this database to learn more about how young onset colorectal cancer may be similar to or different from colorectal cancer that is diagnosed later in life. Researchers will also use information from the database for current and future research on young onset colorectal cancer.

Official Title
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Young Onset Gastrointestinal Cancer Prospective Registry

Conditions
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Colorectal Cancer, Colorectal Carcinoma

Intervention / Treatment
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* Other: Risk Factor Questionnaire


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Participant Inclusion Criteria for database and questionnaire (YOGI) Histological or cytological diagnosis of gastrointestinal cancer 18 - 49 years old at time of consent No Known hereditary CRC or other cancer predisposition syndrome (stool collection cohort only) No history of inflammatory bowel disease (stool collection cohort only) No prior diagnosis of gastrointestinal cancer (stool collection cohort only) Participant Inclusion Criteria for database and questionnaire (Controls) Histological or cytological diagnosis of colorectal adenocarcinoma No previous treatment for CRC (including surgery, chemotherapy, immunotherapy or radiation) Age 50 or older at time of consent No Known hereditary CRC or other cancer predisposition syndrome No history of inflammatory bowel disease No prior diagnosis of CRC

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Young onset Colorectal Cancer Participants<br>(Stool collection on newly diagnosed patients in this cohort) Participants will include patients under the age of 50 who are diagnosed with colorectal adenocarcinoma. | Other: Risk Factor Questionnaire<br>* Participants, both cases and controls, will complete the CYOC risk factor questionnaire, preferably at the time of first visit<br>* Other names: CYOC Risk Factor Questionnaire;|
| Average onset Colorectal Cancer Participants<br>(Stool collection cohort only) 166 colorectal cancer patients 50 year-old or older will serve as controls. Stool collection cohort only. | Other: Risk Factor Questionnaire<br>* Participants, both cases and controls, will complete the CYOC risk factor questionnaire, preferably at the time of first visit<br>* Other names: CYOC Risk Factor Questionnaire;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Establish a prospective database of patients with Young Onset Colorectal Cancer | from diagnosis through survivorship | 1 year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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young onset colorectal cancer, colorectal registry, 20-315, Memorial Sloan Kettering Cancer Center