A Retrospective Analysis of the Adherence to Clinical Practice Guidelines Using the MedicBK Digital Platform in Patients With Hypertension and Atrial Fibrillation

Study Overview
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Brief Summary
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The Clinical Decision Support Systems (CDSS) based on real clinical data and its own algorithms can help to make the right choice. This trial is designed to assess the difference between retrospective electronic medical cards (EMC) therapy prescriptions and MedicBK prescriptions based on key patient characteristics.

Detailed Description
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There is a lot of data from registries about poor adherence to guidelines. It is connected with a problem that patients usually have a lot of comorbidities and physicians need to know сonsequently the huge number of medications and combinations. It is very difficult to decide quickly according to available data from libraries like PubMed. The Clinical Decision Support Systems (CDSS) based on real clinical data and its own Artificial Intelligence algorithms can help to make the right choice. This trial is designed to assess the difference between retrospective electronic medical cards (EMC) therapy prescriptions and MedicBK prescriptions based on key patient characteristics. Two groups of experts (cardiologists with clinical practice for more than 5 years) will be participating in the trial. Using main characteristics from EMC the first group of experts will put this data into MedicBK platform and assess retrospective treatment. The next blinded group of experts will perform prescriptions using MedicBK algorithms based on current guidelines and data from available clinical trials. The main hypothesis is the use Clinical Decision Support Systems (CDSS) better than current clinical practice. This option can help to make the right choice of medical combination based on main patient's clinical characteristics

Official Title
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A Retrospective Analysis of the Adherence to Clinical Practice Guidelines Using the MedicBK Digital Platform in Patients With Hypertension and Atrial Fibrillation (the INTELLECT Trial)

Conditions
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Atrial Fibrillation, Arterial Hypertension

Intervention / Treatment
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* Drug: Retrospective analysis of assigned treatment


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age > 18 years old Patients diagnosed with nonvalvular atrial fibrillation and essential hypertension having indications for therapy according to European guidelines. Exclusion Criteria: Valvular cause of atrial fibrillation GFR less than 30 ml / min Active liver disease Acute coronary syndrome The presence of thyroid diseases as a cause of atrial fibrillation Secondary arterial hypertension

Ages Eligible for Study
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Minimum Age: 19 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Group 1<br>retrospective data on treatment from EMC | Drug: Retrospective analysis of assigned treatment<br>* analysis of treatment assigned by physicians within routine clinical practice<br>|
| Group 2<br>Treatment assignment using medicBC CDSS platform in the same cohort of patients | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Assessment of AF/AH treatment guidelines compliance | Number of electronic medical records not compliant to the AF/AH clinical practice guidelines | 1 MONTH | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Assessment of MedicBK programme | Number of prescriptions from electronic medical records appropriate or inappropriate according to the AF/hypertension clinical practice guidelines in comparison with the treatment's choice of CDSS platform | 1 MONTH | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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atrial fibrillation, arterial hypertension, digital medicine, Clinical Decision Support System