Cardiovascular Risk Factors in an Ambulatory Urban Patient Population

Study Overview
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Brief Summary
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According to WHO estimations, cardiovascular diseases (CVDs) are the number one cause of death globally. More people die annually from CVDs than from any other cause. An estimated 17.5 million people died from CVDs in 2005, representing 30% of all global deaths. Of these deaths, an estimated 7.6 million were due to coronary heart disease and 5.7 million were due to stroke. Over 80% of CVD deaths take place in low- and middle-income countries and occur almost equally in men and women. In Paraguay, prevalence of classic risk factors, as well as new ones, like the metabolic syndrome are not completely known. Government health policies in industrialized countries are focusing on programs to modify cardiovascular risk factors. In developing countries, prevention of coronary heart disease and stroke through modification of cardiovascular risk factors are not playing a large role at the moment. The aim of this study is to define the effects of changes in lifestyle on cardiovascular risk factors, when added to optimized standard pharmacological therapy for arterial hypertension, diabetes mellitus and hyperlipidemia, in an ambulatory urban patient population.

Official Title
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Estimation of Prevalence and Assessment of the Effects of Modification of Cardiovascular Risk Factors in an Ambulatory Urban Patient Population

Conditions
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Cardiovascular Risk Factors, Metabolic Syndrome, Lifestyle Modification, Coronary Artery Disease, Stroke

Intervention / Treatment
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* Behavioral: Dietary and nutritional modification
* Behavioral: Stop smoking
* Behavioral: Regular physical activities
* Behavioral: Weight reduction to normal ranges
* Behavioral: Regular intake of polyphenols, esp. from Ilex paraguayensis


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: all ambulatory patients, with age 18 years or older Exclusion Criteria: no exclusion criteria provided, particularly for the first, epidemiological part of the study

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| asuriesgo<br>unselected outpatient population | Behavioral: Dietary and nutritional modification<br> <br> Behavioral: Stop smoking<br> <br> Behavioral: Regular physical activities<br> <br> Behavioral: Weight reduction to normal ranges<br> <br> Behavioral: Regular intake of polyphenols, esp. from Ilex paraguayensis<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| cardiovascular mortality |  | one year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| mortality, other causes |  | one year | 
| acute myocardial infarction |  | one year | 
| stroke |  | one year | 
| acute coronary syndrome |  | one year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Diet, Exercise, Smoking, Stress, Polyphenols