linjc16/ctgov huggingface dataset:
Comparison of Acupuncture and Fluoxetine on Quality of Life in Menopausal Women

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to comparison the effect of acupuncture and Fluoxetine on improvement quality of life among menopausal women.

Detailed Description
-----------------
This clinical trial is designed in two arm include acupuncture and fluoxetine group to evaluate the effect of these intervention on improvement quality of life among menopausal women.

Official Title
-----------------
Comparison of the Effects of Acupuncture and Fluoxetine on Quality of Life in Menopausal Women

Conditions
-----------------
Hot Flash, Quality of Life

Intervention / Treatment
-----------------
* Procedure: acupuncture
* Drug: fluoxetine


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Last menstrual cycle 12 months ago natural menopause 4 episodes of hot flash daily follicle stimulating hormone (FSH)= 30-110 IU/L , E2<18pg/ml thyroid-stimulating hormone(TSH)= 0.4-4/0 IU/ml No using of herbal agent for treatment of hot flash having score in Beck depression Inventory<10 No existence of any medical problems and using drugs Exclusion Criteria: Not completing all acupuncture sessions Not completing fluoxetine admission Withdraw the study
Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Acupuncture<br>12 sessions of acupuncture / 3 sessions weekly/ 20 minutes each session | Procedure: acupuncture<br>* 12 sessions acupuncture during 12 weeks (3 sessions weekly), each session lasting 20 minutes<br>* Other names: Manual acupuncture;|
| Active Comparator: fluoxetine<br>10 mg daily | Drug: fluoxetine<br>* 10 mg/ daily<br>* Other names: flouxetine;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Quality of life in menopausal women | Quality of life using MENQOL questionnaire | 3 months after start sampling | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Quality of life, Hot flash, Acupuncture, Fluoxetine
Diagnostic Evaluation of the Tear Film

Study Overview
=================
Brief Summary
-----------------
The objectives of this study are to assess for a difference between normal and dry eye subjects in tear film quality using a diagnostic interferometry device and to determine whether there are associations between tear film quality and dry eye symptoms and signs.

Official Title
-----------------
Analysis of the Tear Film Lipid Layer

Conditions
-----------------
Dry Eye Syndromes

Intervention / Treatment
-----------------
* Device: Tear Film Analyzer


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Adults 18 year of age or older Willing and able to comply with study exam procedure Exclusion Criteria: Eyelid abnormality or ocular surface condition affecting ability to visualize tear film Women who are pregnant or nursing Any of the following conditions within specified timeframe prior to study participation: Instillation of eye drops Contact lens wear Use of oil-based facial cosmetics Swimming in chlorinated pool Eye examination procedures that may affect the tear film Participation in another ophthalmic clinical trial

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| 1: Normal<br>Subjects without dry eye symptoms based on questionnaire. | Device: Tear Film Analyzer<br>* tear film images<br>* Other names: ocular surface interferometry;|
| 2: Dry Eye<br>Subjects with dry eye symptoms based on questionnaire. | Device: Tear Film Analyzer<br>* tear film images<br>* Other names: ocular surface interferometry;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Tear film analysis of lipid layer quality |  | upon enrollment | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Dry Eye Symptoms |  | upon enrollment | 
| Tear Film Break-Up Time |  | upon enrollment | 
| Corneal and Conjunctival Staining |  | upon enrollment | 
| Meibomian Gland Assessment |  | upon enrollment | 
| Schirmer Test |  | upon enrollment |
Preoperative Staging of Endometriosis With MRI

Study Overview
=================
Brief Summary
-----------------
The purpose of the study is to evaluate the value of MRI in preoperative stratification of endometriosis patients needing surgical approach by gynaecologists only or multidisciplinary approach by gynaecologists, urologists or/and abdominal surgeons.

Detailed Description
-----------------
The purpose of the study is to evaluate the value of MRI in preoperative stratification of endometriosis patients needing either a surgical approach by gynaecologists only or multidisciplinary approach by gynaecologists, urologists or/and abdominal surgeons.

Official Title
-----------------
Prospective Evaluation of the Value of Magnetic Resonance Imaging as a One-stop-shop for Preoperative Stratification of Patients With Complexe Endometriosis - Imaging Deep Endometriosis Assessment Versus Laparoscopy.

Conditions
-----------------
Endometriosis

Intervention / Treatment
-----------------
* Other: No intervention


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Women with strong suspicion of deep infiltrating endometriosis, with already planned surgery Exclusion Criteria: Contra-indications for MRI; claustrophobic patients; patients in bad condition; pregnancy
Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Women with endometriosis<br>Women with endometriosis with the intention of surgery - no intervention | Other: No intervention<br>* Evaluation of an imaging technique ic MRI<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Odds of changed surgical approach in deep endometriosis based on preoperative MRI findings. | All endometriosis lesions found on MRI will be checked during laparoscopy in order to determine how the MRI findings might have changed the decision to do a surgical approach by gynaecologists only or multidisciplinary approach by gynaecologists, urologists or/and abdominal surgeons, and this compared to the conventional preoperative imaging approach (double contrast barium enema, intravenous urography and ultrasound. | All the imaging findings will be checked during a laparoscopy the latest 80 weeks after the imaging examinations. | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Endometriosis, Magnetic resonance imaging
Standard Sleeve Pouch Versus Relatively Wide Pouch With Plication

Study Overview
=================
Brief Summary
-----------------
three hundred morbidly obese patients candidate for sleeve gastrectomy will divided into equal two groups, group A : will operated by standard sleeve gastrectomy on bougie 36 without plication of stable line and group B: will operated by sleeve gastrectomy on bougie 42 with plication of stable line. the aim is to test the effect of pilcation on the incidence of leaks and bleeding

Detailed Description
-----------------
three hundred morbidly obese patients candidate for sleeve gastrectomy will divided into equal two groups, group A : will operated by standard sleeve gastrectomy on bougie 36 without plication of stable line and group B: will operated by sleeve gastrectomy on bougie 42 with plication of stable line. the primary outcomes is the incidence of leaks and bleeding which is the main nightmare of sleeve gastrectomy, secondary outcome operative time, weight loss and metabolic effect

Official Title
-----------------
Outcomes of Standard Sleeve Pouch Versus Relatively Wide Pouch With Plication

Conditions
-----------------
Obesity, Morbid

Intervention / Treatment
-----------------
* Procedure: sleeve with plication
* Procedure: sleeve without plication


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: obese patients with BMI more than 40 with or without co-morbidity or more than 35 with co-morbidity patients fit for laparoscopic surgery give approval to share in the study Exclusion Criteria: patients refused to share in the study patients unfit for surgery patients aged less than 18 and older than 60 patient with previous upper abdominal surgery either for obesity or other diseases revisional bariatric procedures

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 60 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: sleeve without plication<br>sleeve gastrectomy on bougie 36 without plication | Procedure: sleeve without plication<br>* sleeve without plication<br>|
| Active Comparator: sleeve with plication<br>sleeve gastrectomy on bougie 42 without plication | Procedure: sleeve with plication<br>* sleeve with plication<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the incidence of postoperative stable line bleeding | early postoperative bleeding from stable line | 2-24 hours | 
| the incidence of stable line leakage | leak from stable line | 1-30 days | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
post sleeve gastrectomy leak, post sleeve gastrectomy
Thin Bronchoscope and Virtual Bronchoscopic Navigation System for Tuberculosis

Study Overview
=================
Brief Summary
-----------------
This study investigates the utility of thin bronchoscope and virtual bronchoscopic navigation system (targeted bronchial washing) for detection of M. tuberculosis and resistant-conferring mutations in patients with pulmonary tuberculosis. Time to appropriate treatment and stain/culture conversion are also evaluated.

Detailed Description
-----------------
Comparisons of detection rate of M. tuberculosis and resistant-conferring mutations between patients who perform CT-guided conventional bronchoscope and patients who perform VBN-guided thin bronchoscope.

Official Title
-----------------
Thin Bronchoscope and Virtual Bronchoscopic Navigation System for Rapid Detection of Mycobacterium Tuberculosis and Resistant-conferring Mutations

Conditions
-----------------
Tuberculosis

Intervention / Treatment
-----------------
* Device: Thin bronchoscope and VBN


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: age of 18 or more persons who are suspected with pulmonary tuberculosis on radiologic examination persons who cannot spit sputum or persons with negative results on sputum AFB smear and TB-PCR or Xpert MTB/RIF assay Exclusion Criteria: persons who do not agree with bronchoscopy (persons who want empirical treatment for TB) persons with contraindications for bronchoscopy bleeding tendency uncontrolled respiratory disease (hypoxemia) uncontrolled cardiovascular disease

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: Conventional arm<br>Perform bronchial washing using conventional methods. CT-guided thick bronchoscope | |
| Active Comparator: Investigational arm<br>Perform bronchial washing using investigational methods. virtual bronchoscopic navigation (VBN)-guided thin bronchoscope (4.0mm of outer diameter) | Device: Thin bronchoscope and VBN<br>* targeted washing at more adjacent TB lesion using thin bronchoscope and virtual bronchoscopic navigation system<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| detection of M. tuberculosis and resistant-conferring mutations | evaulation by sensitivity, specificity, PPV and NPV | 2months after procedure | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| time to appropriate treatment and stain/culture conversion | date of treatment initiation and stain/culture negative conversion | 6months after procedure |
Optimization of EKG Method for Long Term Central Venous Catheter Tip Placement

Study Overview
=================
Brief Summary
-----------------
Intravenous electrocardiographic guidance (IVECG) is a safe, reliable and accurate technique to correctly position the catheter tip. The investigators sought to evaluate the superiority of the P-maximal (P-max) wave compared to the P-submaximal (P-submax) wave in obtaining a more correct, safer and longer lasting device placement, with a lower incidence of complications and secondary misplacement.

Detailed Description
-----------------
This prospective randomized trial was designed to observe the placement of long term iv catheters obtained with the IVECG method. Patients were randomised into 2 groups: in group A the catheter tip was placed in correspondence to the P-max, in group B in correspondence to the P-submax. We followed up the tip position by measuring the variation of its distances from the tracheal carina on multiplanar reconstructions of volumetric CT scans taken within a month (T0) and a year (T1) from the port implant.

Official Title
-----------------
P-max or P-submax? This is the Question! A Prospective Randomized Search of the Most Reliable ECG Landmark for a Long Term Central Venous Catheter.

Conditions
-----------------
Vascular Access Complication

Intervention / Treatment
-----------------
* Device: P-Max
* Device: P-Submax


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: indication to chemo port insertion ability to give informed consent Exclusion Criteria: younger than 18 inability to give consent atrial fibrillation or flutter pace-maker or implantable cardioverter-defibrillator

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: P-Max group<br>Includes cases in which the catheter tip was considered correctly positioned when the Maximal P wave was obtained | Device: P-Max<br>* tip placement in correspondence to the P-Max on the ECG<br>|
| Active Comparator: P-Submax group<br>Includes cases in which the catheter tip was considered correctly positioned when the Submaximal P wave was obtained | Device: P-Submax<br>* tip placement in correspondence to the P-Submax on the ECG<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Distance between tracheal carina and distal end of the catheter |  | up to 10 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
chemo port, intravenous electrocardiographic guidance, P maximal wave, P submaximal wave, catheter tip
The Professional Values and Ethical Sensitivities During the COVID-19 Pandemic

Study Overview
=================
Brief Summary
-----------------
This study was conducted to examine the professional values and ethical sensitivities of senior nursing students in distance education during the COVID-19 pandemic. During the COVID-19 process, senior nursing students continue their education with distance education practices. The sample consisted of 302 senior nursing students.

Official Title
-----------------
The Professional Values and Ethical Sensitivities of Turkish Senior Nursing Students in Distance Education During the COVID-19 Pandemic

Conditions
-----------------
Professional Values, Ethical Sensitivities

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: being over the age of 18 being a fourth level student agreed to participate in the research Exclusion Criteria: being diagnosed with a neuropsychiatric disease

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The first evaluation- Pre-test | the Nurses Professional Values Scale-Revised Score (The total score obtained from the scale varies between 26 and 130. A high score indicates strong adherence to professional values.) | February-2020 | 
| The first evaluation- Pre-test | Modified Moral Sensitivity Questionnaire for Student Nurses Score (The total score obtained from the scale is between 30 and 210. A high score indicates high ethical sensitivity.) | February-2020 | 
| The second evaluation- Post-test | the Nurses Professional Values Scale-Revised Score (The total score obtained from the scale varies between 26 and 130. A high score indicates strong adherence to professional values.) | July-2020 | 
| The second evaluation- Post-test | Modified Moral Sensitivity Questionnaire for Student Nurses Score (The total score obtained from the scale is between 30 and 210. A high score indicates high ethical sensitivity.) | July-2020 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
COVID-19, ethical sensitivity, nursing student, professional value
Propofol Versus Sevoflurane for Induction of GA in Infants

Study Overview
=================
Brief Summary
-----------------
This comparative study aims to investigate the haemodynamic safety profile for induction of general anesthesia in infants 3 months or less guided by electrical cardiometry parameters versus sevoflurane.

Detailed Description
-----------------
This study aims to investigate the hemodynamic effects of both propofol and sevoflurane for induction of anesthesia in infants less than 3 months of age by electrical cardiometry. The investigators hypothesized that propofol will have a safe hemodynamic profile for induction of anesthesia in infants less than 3 months of age as measured by electrical cardiometry in addition to its favorable pharmacokinetic profile of rapid induction and optimal intubation conditions.It is conducted at Abu Al Reesh Children's Hospital, Faculty of Medicine, Cairo University based on an institutional protocol used as a standard of care to induce anesthesia

Official Title
-----------------
The Hemodynamic Effects of Propofol Versus Sevoflurane for Induction of Anesthesia in Healthy Infants as Measured by Electrical Cardiometry: Randomized Controlled Trial

Conditions
-----------------
Induction of General Anesthesia

Intervention / Treatment
-----------------
* Drug: Propofol


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: infants aged 3 months or less scheduled for elective surgery Exclusion Criteria: significant structural congenital heart disease intracranial malformation. preexisting hemodynamic instability. history of seizures, opioids, and/or hypnotic administration. prematurity (defined as gestational age <37 weeks)

Ages Eligible for Study
-----------------
Minimum Age: 1 Day
Maximum Age: 90 Days

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: propofol<br>Propofol at a dose of 2mg/kg will be administered I.V. . | Drug: Propofol<br>* Intravenous induction of general anesthesia in infants 3 months or less.<br>|
| Active Comparator: Sevoflurane<br>Sevoflurane (4%) will be used for inhalational induction. | Drug: Propofol<br>* Intravenous induction of general anesthesia in infants 3 months or less.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| cardiac index | L/min/m2 | 15 minutes | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| MAP | mmHg | 15 minutes |
DNA Typing of HLA-DR/DQ Alleles in Taiwan Chinese With Rheumatic Heart Disease

Study Overview
=================
Brief Summary
-----------------
The current study was designed to determine whether the HLA-DRB1, DQA1, DQB1 alleles are associated with the risk and the pattern of valve damage of RHD.

Conditions
-----------------
Rheumatic Heart Disease

Intervention / Treatment
-----------------
* Procedure: venipuncture to withdraw patient's blood


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 1.Patients with Rheumatic mitral stenosis 2.Chinese Han ethnicity Exclusion Criteria: -

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Allocation: Non-Randomized
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: venipuncture to withdraw patient's blood|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Rheumatic heart disease, HLA, Genetics, Taiwan