Assessment of Correlation Between Changes of Shear Wave Elastography and Surface Electromyogram of the Masseter

Study Overview
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Brief Summary
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Diagnoses and follow up of muscles diseases lack imaging. Severity assessment of masticatory dysfunction and follow up of treatment effectiveness is currently based only on clinical features. Supersonic ShearWave Imaging® is a new, non-invasive, non-irradiating and dynamic imaging technique that uses ultrasound and allows shear wave elastic modulus in a muscle in order to study its viscoelastic properties. In this study, the investigators study the correlation between changes of shear wave elastography modulus and surface electromyogram features of the masseters between rest and maximal voluntary contraction.

Official Title
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Assessment of Correlation Between Changes of Shear Wave Elastography and Surface Electromyogram of the Masseter, in Rest and Maximal Voluntary Contraction

Conditions
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Masseter Muscle Spasm

Intervention / Treatment
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* Device: Ultrasound exam by Supersonic Shear Imaging® technique
* Device: EMG examination by electromyograph Keypoint system


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: People with social security. People aged 20 to 40 years, of both sexes. People that gave and signed consent to participate in the study. Exclusion Criteria: Any concomitant muscle disease (myopathy, myositis…) Botulinum toxin injections in the masseter in the last 3 months preceding the study. Any treatment that induces muscular effect (baclofen, benzodiazepine) Bruxism or any masticatory apparatus disease Any surgery of the masticatory apparatus

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 40 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Experimental group<br>ultrasound exam by Supersonic Shear Imaging® technique EMG examination by electromyograph Keypoint system. | Device: Ultrasound exam by Supersonic Shear Imaging® technique<br>* Each of the two observers performs twice ultrasound examination and measures of the masseter thickness and its elastic modulus, at rest and maximal voluntary contraction.<br>Device: EMG examination by electromyograph Keypoint system<br>* Experimented neurologist performs EMG examination.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Elastic modulus using Supersonic Shear Imaging® technique on superficial and deep masseter parts at rest and maximal voluntary contraction. |  | Day 1 (inclusion day) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Thickness of the whole masseter mesured by Supersonic Shear Imaging® technique |  | Day 1 (inclusion day) | 
| Thickness of the masseter superficial part mesured by Supersonic Shear Imaging® technique |  | Day 1 (inclusion day) | 
| Thickness of the masseter deep part mesured by Supersonic Shear Imaging® technique |  | Day 1 (inclusion day) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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shear wave elastography, surface electromyogram, masseter