linjc16/ctgov huggingface dataset:
Comparison of Three Laryngoscope Blades for Orotracheal Intubation in the Operating Room

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to determinate if there is a difference in performance provided by three laryngoscope blades: plastic single use, metallic single use and metallic reusable blades.

Detailed Description
-----------------
Primary outcome: success of intubation at the first attempt Secondary outcomes: quality of laryngeal exposition (Cormack and Lehanne modify grade), duration to success intubation, Intubation difficult Scale and result of intubation procedure

Official Title
-----------------
Comparison of Performance of Three Laryngoscope Blades: Plastic Single Use, Metallic Single Use and Metallic Reusable Blades.

Conditions
-----------------
Intubation

Intervention / Treatment
-----------------
* Device: metallic single use blade
* Device: plastic single use blade
* Device: metallic reusable blade


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patient age over 18 who need general anesthesia with orothracheal intubation Exclusion Criteria: patient age under 18 or major assist presence of upper airway malformation or abnormality cervical or facial trauma previous difficult intubation known no use of curare Body Mass Index over 30kg/m2 if crush induction use

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 1<br>metallic single use blade | Device: metallic single use blade<br>* metallic single use blade<br>|
| Experimental: 2<br>plastic single use blade | Device: plastic single use blade<br>* plastic single use blade<br>|
| Active Comparator: 3<br>metallic reusable blade | Device: metallic reusable blade<br>* metallic reusable blade<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| success of intubation at the first attempt |  | immediately | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| quality of laryngeal exposition (Cormack and Lehanne modify grade) |  | immediately | 
| duration to success intubation |  | immediately | 
| Intubation difficult Scale |  | Immediately | 
| result of intubation procedure |  | immediately | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
anesthesiology, randomized, laryngoscope, intubation, laryngeal exposition, laryngoscope blades, plastic single use blade, metallic single use blade, metallic reusable blade, success to intubation at first attempt, Cormack and lehanne modify grade
Preparing for Kidney Transplant by Attaining a Healthy Weight

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to determine if an assigned physical fitness program will result in weight loss to prepare patients for kidney transplant.

Detailed Description
-----------------
The goal of this study is to prepare subjects for kidney transplant. Patients who are in need of a kidney transplant but are unable to be place on the wait list due to weight will be enrolled in a six month workout program. The workout program will consist of counseling from a registered dietician, personal training from certified trainers and constant health monitoring.

Official Title
-----------------
Preparing for Kidney Transplant by Attaining a Healthy Weight

Conditions
-----------------
Kidney Transplant

Intervention / Treatment
-----------------
* Other: Exercise
* Dietary Supplement: Diet Plan


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Adult patients over 18 years of age and older but less than 65 All patients who are currently listed as inactive on the University of Chicago kidney transplant wait list Those with a body mass index of 40-44 Those with access to the Internet Have transportation to the fitness center (Formula Fitness Center at Union Station location) Exclusion Criteria: Those patients who are listed inactive on the wait-list due to co-morbid conditions other than obesity Those who are unwilling to attend fitness center appointments Those who do not have adequate transportation to the fitness center Those who do not have access to the Internet Those who are not comfortable navigating and using the Internet

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Treatment<br>Subjects receive a diet plan and exercise regimen. | Other: Exercise<br>* 6 months worth of exercise regimen<br>Dietary Supplement: Diet Plan<br>* Each subject will receive a personalized diet plan from nutritionist.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Weight Loss | The difference in starting weight and ending weight six months after beginning exercise program will be measured. | 6 months |
Automatic Classification of Colorectal Polyps Using Probe-based Endomicroscopy With Artificial Intelligence

Study Overview
=================
Brief Summary
-----------------
Probe-based confocal laser endomicroscopy (pCLE) is an endoscopic technique that enables real-time histological evaluation of gastrointestinal mucosa during ongoing endoscopy examination. It can predict the classification of Colorectal Polyps accurately. However this requires much experience, which limits the application of pCLE. The investigators designed a computer program using deep neural networks to differentiate hyperplastic from neoplastic polyps automatically in pCLE examination.

Official Title
-----------------
Automatic Classification of Colorectal Polyps Using Probe-based Endomicroscopy With Artificial Intelligence

Conditions
-----------------
Probe-based Confocal Laser Endomicroscopy, Artificial Intelligence, Colorectal Polyps

Intervention / Treatment
-----------------
* Other: AI presentation


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: aged between 18 and 80; agree to give written informed consent. Exclusion Criteria: Patients under conditions unsuitable for performing CLE including coagulopathy , impaired renal or hepatic function, pregnancy or breastfeeding, and known allergy to fluorescein sodium; Inability to provide informed consent

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: AI visible group<br> | Other: AI presentation<br>* Automatic diagnosis information of AI is visible to endoscopist<br>|
| No Intervention: AI invisible group<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The accuracy of classifying colorectal Polyps using Probe-based endomicroscopy with deep neural networks | The primary outcome is to test the diagnostic accuracy, sensitivity, specificity, PPV, NPV of the Artificial Intelligence for diagnosing Colorectal Polyps on real-time pCLE examination. | 4 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Contrast the diagnosis efficiency of Artificial Intelligence with endoscopists | The secondary outcome is to compare the diagnosis efficiency (including diagnostic accuracy, sensitivity, specificity, PPV, NPV for diagnosing Colorectal Polyps on real-time pCLE examination) between Artificial Intelligence and endoscopists. | 3 month |
SENSIMED Triggerfish in Closed Eyes

Study Overview
=================
Brief Summary
-----------------
This study investigates the effect of eye opening/closure on the quality of IOP (intraocular pressure) related patterns recorded with SENSIMED Triggerfish. Each subject receives 2 24-hour recording sessions, one with the recorded eye open and the other with the eye closed,using an ophthalmic patch.

Official Title
-----------------
A Prospective, Open Label Study to Assess the 24-hour Intraocular Pressure Pattern Recorded With SENSIMED Triggerfish® in Healthy Subjects With Closed Eye

Conditions
-----------------
Glaucoma

Intervention / Treatment
-----------------
* Device: SENSIMED Triggerfish


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Healthy subject without previous ophthalmic medical history (except from indication for glasses) Aged ≥18 years, of either sex Have given written informed consent, prior to any investigational procedures Exclusion Criteria: Patients with allergy to corneal anesthetic Patients with contraindications for silicone contact lens wear Patients not able to understand the character and individual consequences of the investigation Participation in other clinical research within the last 4 weeks

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 100 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: SENSIMED Triggerfish<br> | Device: SENSIMED Triggerfish<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The difference between start and end TF (SENSIMED Triggerfish) in a closed eye as compared to the difference between start to end TF in an open eye | TF will be installed on subjects' eyes for 24 hours in two sessions. In one session the eye will remain open (except during sleep) while in the other session the eye will be closed using an ophthalmic patch throughout the 24 hours. For both sessions, the initial TF output value in millivolt equivalent will be subtracted from the final output value to yield the difference from start to end. The difference obtained in the session with closed eye will be divided by that of the session with open eye (ratio). | 24 hours |
Brain Functions in Patients Before and After Bariatric Surgery

Study Overview
=================
Brief Summary
-----------------
The project will specifically focus on the examination of the influence of substantial weight loss due to bariatric surgery on brain functions. Our hypothesis is that substantial weight loss after Bariatric Surgery (BS) is also accompanied by changes in the balance of reward and inhibitory networks in diabetic subjects. Therefore the investigators will conduct a functional magnetic resonance imaging (fMRI) study investigating functional measures.

Conditions
-----------------
Adiposity

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: bariatric surgery in the past or in the future diabetes (at least before surgery) Exclusion Criteria: fMRI contraindications claustrophobia

Ages Eligible for Study
-----------------
Minimum Age: 25 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| pre bariatric surgery<br> | |
| post bariatric surgery<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Differential brain functions | brain functions will be measured by blood oxygen level dependent effects | at least 6 months after bariatric surgery (experimental group) |
Clinical Evaluation of a Wearable Technology for the Diagnosis of Sleep Apnoea

Study Overview
=================
Brief Summary
-----------------
This trial will aim to test a new wearable device for the diagnosis of Sleep Apnoea.

Detailed Description
-----------------
This clinical trial will test a new wearable device for the diagnosis of Sleep Apnoea against Multi-channel polygraphy and Polysomnography.

Official Title
-----------------
Evaluación clínica de Una tecnología Ambulatoria Para diagnóstico Del sueño

Conditions
-----------------
Obstructive Sleep Apnea

Intervention / Treatment
-----------------
* Diagnostic Test: Novel Wearable device


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients who have been referred to a sleep clinic due to suspicion of sleep apnoea. patients between the age of 18 yo and 80 yo Exclusion Criteria: who are not fluent in Spanish, or who have special communication needs. Known allergy to the adhesive dressing. patients with physical or mental impairments who would not be able to use the new technology on their own. patients with very loose/saggy skin in the neck area which would unavoidably result on AcuPebble swinging if moving the neck. patients with pacemakers or who have any type of implanted electronic device

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| PSG and novel wearable device<br>75 patients will wear polysomnography at the same time as the Novel wearable device | Diagnostic Test: Novel Wearable device<br>* patient will wear novel wearable device overnight along with normal standard of care<br>|
| PG and novel wearable device<br>75 patients will wear polygraphy at the same time as the novel wearable device | Diagnostic Test: Novel Wearable device<br>* patient will wear novel wearable device overnight along with normal standard of care<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Sensitivities and Specificity for diagnosis of sleep apnoea studies with novel wearable device | The study aims to compare the diagnosis result of the novel wearable device against standard of care | 6 months |
The Efficacy, Tolerability and Safety of Donepezil (Aricept) in Parkinson's Disease Patients With Dementia

Study Overview
=================
Brief Summary
-----------------
A randomised, double-blind, 3-arm parallel group study comparing Aricept® with placebo.

Conditions
-----------------
Dementia With Parkinson's Disease

Intervention / Treatment
-----------------
* Drug: ARICEPT


Participation Criteria
=================
Eligibility Criteria
-----------------
Patients with an established diagnosis of PD and dementia, who fulfill all of the inclusion criteria and none of the exclusion criteria listed below, will be eligible for enrolment into this study. Best efforts must be made on clinical grounds to exclude patients with DLB and AD. The key inclusion criteria in this respect is the onset of dementia documented to have occurred at least 1 year after the diagnosis of PD.

Ages Eligible for Study
-----------------
Minimum Age: 40 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: ARICEPT|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| PD patients with dementia will be screened up to 4 weeks prior to initiating dose administration. Baseline measurement on efficacy measures will be conducted at baseline, after which the first dose of study medication will be administered. |  |  |
Evaluation of Breastfeeding Success and Self-Efficacy in Mothers Giving Birth Via Vaginal Delivery or Cesarean Section

Study Overview
=================
Brief Summary
-----------------
This cross-sectional observational study was conducted to compare breastfeeding success and breastfeeding self-efficacy levels of mothers who gave birth via vaginal delivery (spontaneous or via epidural analgesia) or cesarean section (under general or spinal anesthesia).

Detailed Description
-----------------
This study was conducted by including women, who gave birth via VD or CS in the gynecology clinics of a training and research hospital and a city hospital and were in the postpartum period (after 24 hours). It compared the breastfeeding self-efficacy and breastfeeding success of mothers who gave birth via CS (under spinal anesthesia or general anesthesia) with those of mothers who gave birth via vaginal delivery (under epidural analgesia or via spontaneous vaginal delivery).

Official Title
-----------------
Evaluation of Breastfeeding Success and Self-Efficacy Using LATCH in Mothers Giving Birth Via Vaginal Delivery or Cesarean Section: Cross-sectional Study

Conditions
-----------------
Breastfeeding

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: being aged >18 years old; being literate; having a baby of weight between 2500-4000 g, with 5th minute APGAR score of ≥7, and without congenital diseases and sucking and swallowing problems; not having a disease that prevents breastfeeding; having a full-term (37-42 weeks) VD or CS, agreeing to participate in the study Exclusion Criteria: a history of psychological or mental health problems any condition in the mother or infant that was a barrier to breastfeeding baby's admission into the neonatal unit baby's separation from the mother for any reason

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Breastfeeding success observing | assessed using the LATCH Breastfeeding Assessment Tool | Postpartum 24 hours | 
| Breastfeeding Self-Efficacy | assessed using the Breastfeeding Self-Efficacy Scale-Short Form (BSES-SF) | Early postpartum period (after 24 hours) | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Breastfeeding Success, breastfeeding Self-Efficacy, vaginal delivery, cesarean section, spinal anesthesia, general anesthesia, epidural anestezi
Score Infectivity During Reoperation on Total Hip or Knee Prosthesis

Study Overview
=================
Brief Summary
-----------------
The hip or knee is a validated treatment of end-stage osteoarthritis, and these interventions commonly make a significant improvement in the quality of life of patients. Infection can occur in 1-5% of cases. Diagnosis is often difficult, but the knowledge of infected or not infected character directly influences the surgical conduct. It is therefore recommended that the positive or negative diagnosis is made in the most reliable way possible, but no single element only allows a low diagnosis. The concomitant use of several clinical, radiological and aggregated into a composite score history could help facilitate this preoperative approach during reoperation on prosthetic joint

Official Title
-----------------
Definition of a Score Infectivity During Reoperation on Total Hip or Knee Prosthesis

Conditions
-----------------
Osteoarthritis

Intervention / Treatment
-----------------
* Other: Retrospective study


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients over 18 years Patients operated in the service in 2014 to care for end-stage hip or knee osteoarthritis by implantation of a total hip or knee prosthesis. Exclusion Criteria: Patients under 18 years

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Retrospective study|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| define a composite score on total Hip or Knee Prosthesis |  | patient's medical data will be collected by health professional for the duration hospital stay, up to 1 year] | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Knee, Knee osteoarthritis, Knee replacement, Hip, Hip osteoarthritis, Hip replacement