Infant & Toddler Short Gut Feeding Outcomes Study

Study Overview
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Brief Summary
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The purpose of this study is to better understand why children with short gut develop feeding problems.

Detailed Description
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We seek to identify characteristics of our patients' histories that are associated with feeding problems in the context of availability of early prophylactic occupational therapy. We plan to review our most recent four years' experience in children with short gut syndrome with onset in early infancy who initially required home parenteral nutrition to identify risk factors or clusters of risk factors associated with food aversion.

Official Title
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Infant & Toddler Short Gut Feeding Outcomes Study

Conditions
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Short Bowel Syndrome, Intestinal Failure, Home Parenteral Nutrition

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients seen in home-TPN clinic since July of 2008 with: Intestinal failure Short gut Onset < 3 months of age Received home parenteral nutrition following initial hospital discharge Less than 7 years of age at time of study Must have at least 1 parent/legal guradian willing to participate in the study Exclusion Criteria: Not seen in home TPN clinic Short gut with onset >3 months No parents/legal guradians willing to participate in the study

Ages Eligible for Study
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Minimum Age: 3 Months
Maximum Age: 6 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Short bowel syndrome<br>Patients followed in a clinic for short bowel syndrome | |
| Healthy controls<br>Patients seen in a general pediatric clinic without chronic or acute diseases | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Retrospective data | Data will be reviewed starting at the patient's birth. We will only be looking at patients who have been seen in the clinic since July 1, 2008; some of these will have medical records going back as early as 2006. We will continue to collect future data for up to 1 year from the beginning of data collection. | up to 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Validated Questionnaires | Validated questionnaires (where available) will be administered prospectively to grade current feeding competence for age, assess developmental status, assess food preferences and score parental stress. Only the food preference questionnaire will be administered to the healthy control group. | 2 hours | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Short Gut, Short Bowel Syndrome, Intestinal Failure, Home parenteral nutrition, Feeding Behavior, Enteral Nutrition, Parent-Child Relations, Parenteral Nutrition, Digestive System Diseases