Physiotherapy for Children With Dysfunctional Breathing

Study Overview
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Brief Summary
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Dysfunctional breathing in children primarily affects the ability to participate in sport or exercise but can also stop children doing other activities such as playing musical instruments. Clinical experience has shown that physiotherapy (through the use of breathing retraining and other associated techniques) can stop the symptoms of dysfunctional breathing, allowing children to return to normal activities and reduce or stop inhaled medications. Whilst there is some evidence in adults with this condition to support the use of physiotherapy, there have been no studies carried out in children investigating whether physiotherapy is beneficial for children with dysfunctional breathing. This study therefore aims to investigate the feasibility of a future large scale multicentre clinical trial designed to investigate whether physiotherapy improves outcomes for children with dysfunctional breathing. The improved management of this common but under recognised condition would lead to significant improvements in the quality of life of children coupled with the reduction in potentially harmful medications.

Official Title
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Feasibility Study for a Multi-centre Trial Investigating Whether Physiotherapy Improves Outcomes for Children With Dysfunctional Breathing

Conditions
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Dysfunctional Breathing

Intervention / Treatment
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* Behavioral: Physiotherapy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Aged 8-16 years Clinical diagnosis of dysfunctional breathing Exclusion Criteria: Uncontrolled comorbidities Participant and parents/guardians not fluent in written and spoken English Inability to follow instructions

Ages Eligible for Study
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Minimum Age: 8 Years
Maximum Age: 16 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 1<br>The study contains a single arm. All children participating in the study will receive the primary intervention which is physiotherapy. | Behavioral: Physiotherapy<br>* A course of breathing retraining delivered by a physiotherapist and practiced by the participant at home.<br>* Other names: None - Inhalers and scans are not interventions;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Child and parent proxy report versions of the quality of life questionnaire(PedsQL) | To measure participant and parent proxy report of quality of life in the four domains of physical, emotional, social and school functioning | 24 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Symptom questionnaire (Nijmegen questionnaire) | To measure the type and frequency of symptoms commonly associated with dysfunctional breathing | 24 months | 
| Structured light plethysmography (SLP) scan (Thora-3DI) | To objectively measure breathing pattern and rate without influencing these parameters | 24 months | 
| Reliever inhaler usage recorded using a data logger device | To measure usage of inhaled reliever medication | 24 months |