Ultrasound Comparison of the Surface of the Subclavian and the Axillary Vein Versus the Surface of the Subclavian Vein

Study Overview
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Brief Summary
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The main objective of this study is the demonstration of an increase of over 50% of the surface visible on ultrasound (mm2) of the axillary vein and subclavian vein in arm abduction (90 °) and external rotation (90 °) with respect to the surface of the subclavian vein along the arm body.

Detailed Description
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The secondary objective of this study is to investigate the anatomical relationships of these veins with the subclavian artery, the brachial plexus and the pleura, and assess the depth of the vein to the skin. Specifically, the following will be assessed: the depth of the vein (mm) the length of the minor axis (mm) the length of the major axis (mm) artery-vein distance (mm) vein-pleural distance (mm) the distance of the brachial plexus (mm)

Official Title
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Ultrasound Comparison of the Surface of the Subclavian Vein (Arm in Abduction (90°) and External Rotation (90 °)) and the Surface of the Axillary Vein (Arms Along the Body) Versus the Surface of the Subclavian Vein (Arm Along the Body)

Conditions
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Healthy Volunteers

Intervention / Treatment
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* Procedure: Ultrasound measures


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: The volunteer must have given his/her informed and signed consent The volunteer must be insured or beneficiary of a health insurance plan The volunteer is 18 to 50 years old Exclusion Criteria: The volunteer is participating in another study The volunteer is in an exclusion period determined by a previous study The volunteer is under judicial protection, under tutorship or curatorship The volunteer refuses to sign the consent It is impossible to correctly inform the volunteer The volunteer is pregnant, parturient, or breastfeeding The volunteer has a contraindication for the exams in this study Volunteer with a history of trauma or surgery in the axilla or the shoulder girdle Volunteer with a known history of venous thrombosis in the axillary and / or subclavian veins

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 50 healthy volunteers<br>The study population consists of healthy volunteers aged 18 to 50 years and without previous surgery, trauma, or thrombosis of the axilla or the shoulder girdle. | Procedure: Ultrasound measures<br>* Ultrasound will be used to measure the surfaces of the axillary and subclavian veins with the arms in different positions. Our goal is to compare the vein surface area available among different vein-position combinations. Our goal does not include testing specific devices.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| vein surface (mm^2), subclavian vein with arm along side the body |  | baseline (transversal); Day 0 | 
| vein surface (mm^2), subclavian vein with arm in abduction and external rotation |  | baseline (transversal); Day 0 | 
| vein surface (mm^2), axillary vein with arm along side the body |  | baseline (transversal); Day 0 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Vein depth (mm), subclavian vein with arms along side the body |  | baseline (transversal); Day 0 | 
| Length of minor axis (mm), subclavian vein with arms along side the body |  | baseline (transversal); Day 0 | 
| Length of major axis (mm), subclavian vein with arms along side the body |  | baseline (transversal); Day 0 | 
| Artery-vein distance is displayed in the section plane? yes/no | Ultrasound of subclavian vein with arm along side the body. | baseline (transversal); Day 0 | 
| Artery-vein distance (mm) | Ultrasound of subclavian vein with arm along side the body. Artery-vein distance is displayed in the section plane? = yes | baseline (transversal); Day 0 | 
| The vein-pleura distance is displayed in the section plane? yes/no | Ultrasound of subclavian vein with arm along side the body. | baseline (transversal); Day 0 | 
| Vein-pleura distance (mm) | Ultrasound of subclavian vein with arm along side the body. The vein-pleura distance is displayed in the section plane? = yes | baseline (transversal); Day 0 | 
| The distance to the brachial plexus is visualized in the sectional plane? yes/no | Ultrasound of subclavian vein with arm along side the body. | baseline (transversal); Day 0 | 
| Distance to brachial plexus (mm) | Ultrasound of subclavian vein with arm along side the body. The distance of the brachial plexus is visualized in the sectional plane? = yes | baseline (transversal); Day 0 | 
| Vein depth (mm), subclavian vein with arm in abduction and external rotation |  | baseline (transversal); Day 0 | 
| Length of minor axis (mm), subclavian vein with arm in abduction and external rotation |  | baseline (transversal); Day 0 | 
| Length of major axis (mm), subclavian vein with arm in abduction and external rotation |  | baseline (transversal); Day 0 | 
| Vein depth (mm), axillary vein with arm along side the body |  | baseline (transversal); Day 0 | 
| Length of minor axis (mm), axillary vein with arm along side the body |  | baseline (transversal); Day 0 | 
| Length of major axis (mm), axillary vein with arm along side the body |  | baseline (transversal); Day 0 | 
| Artery-vein distance is displayed in the section plane? yes/no | Ultrasound of subclavian vein with arm in abduction and external rotation. | baseline (transversal); Day 0 | 
| Artery-vein distance (mm) | Ultrasound of subclavian vein with arm in abduction and external rotation. Artery-vein distance is displayed in the section plane? = yes | baseline (transversal); Day 0 | 
| The vein-pleura distance is displayed in the section plane? yes/no | Ultrasound of subclavian vein with arm in abduction and external rotation. | baseline (transversal); Day 0 | 
| The distance to the brachial plexus is visualized in the sectional plane? yes/no | Ultrasound of subclavian vein with arm in abduction and external rotation. | baseline (transversal); Day 0 | 
| Vein-pleura distance (mm) | Ultrasound of subclavian vein with arm in abduction and external rotation. The vein-pleura distance is displayed in the section plane? = yes | baseline (transversal); Day 0 | 
| Distance to brachial plexus (mm) | Ultrasound of subclavian vein with arm in abduction and external rotation. The distance of the brachial plexus is visualized in the sectional plane? = yes | baseline (transversal); Day 0 | 
| Artery-vein distance is displayed in the section plane? yes/no | Ultrasound of axillary vein with arm along side the body. | baseline (transversal); Day 0 | 
| Artery-vein distance (mm) | Ultrasound of axillary vein with arm along side the body. Artery-vein distance is displayed in the section plane? = yes | baseline (transversal); Day 0 | 
| The vein-pleura distance is displayed in the section plane? yes/no | Ultrasound of axillary vein with arm along side the body. | baseline (transversal); Day 0 | 
| Vein-pleura distance (mm) | Ultrasound of axillary vein with arm along side the body. The vein-pleura distance is displayed in the section plane? = yes | baseline (transversal); Day 0 | 
| Distance to brachial plexus (mm) | Ultrasound of axillary vein with arm along side the body. The distance of the brachial plexus is visualized in the sectional plane? = yes | baseline (transversal); Day 0 | 
| The distance to the brachial plexus is visualized in the sectional plane? yes/no | Ultrasound of axillary vein with arm along side the body. | baseline (transversal); Day 0 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Axillary vein ultrasound, Subclavian vein ultrasound