Preoperative Antiseptic in Newborn Circumcision Comparison of Povidone Iodine and Hypochlorous Acid Used

Study Overview
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Brief Summary
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Comparison of Povidone iodine and Hypochlorous acid used as a Preoperative Antiseptic in Newborn Circumcision abstract Aim: Circumcision is one of the most common surgical procedures in all age groups. Before the circumcision procedure, asepsis is provided with a surface disinfectant. Various methods can be used for this process. Povidone iodine, which has been used for years during the transition from traditional circumcision methods to surgical circumcision methods; tissue damage, allergic reactions and increase in pain level. For this reason, the investigators aimed to compare it with Hypochlorous acid (Crystalin), which is a less toxic and more physiological antiseptic solution. Material and Method: Newborns to be circumcised randomly were divided into two groups as Hypochlorosis group and Povidone iodine group. At the beginning of the circumcision procedure, a culture was taken in the form of a prepucial swab 1 minute after the cleaning of the local area and the inner surface of the prepuce. Then circumcision was performed. Culture results and complications were compared.

Detailed Description
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It is aimed to compare two solutions used for cleaning the operation area in newborn circumcision.It was conducted to compare the antibacterial activity of povidone iodine and hypochlorous.

Official Title
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Comparison of Povidone Iodine and Hypochlorous Acid Used as a Preoperative Antiseptic in Neonatal Circumcision

Conditions
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Newborn; Infection, Disinfection, Circumcision

Intervention / Treatment
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* Drug: hypochlorous acid


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: male newborn, Exclusion Criteria: hipospadias, epispadias, urinary infectious

Ages Eligible for Study
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Minimum Age: 1 Day
Maximum Age: 1 Month

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Allocation: Randomized
Intervention Model: Sequential Assignment
Interventional Model Description: Two models:Newborns to be circumcised randomly were divided into two groups as Hypochlorosis group and Povidone iodine group.
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Hypochlorosis<br>Hypochlorosis was used as an antiseptic for the patients | Drug: hypochlorous acid<br>* Randomize<br>* Other names: povidone iodine;|
| Active Comparator: Povidone iodine<br>Povidone iodine was used as an antiseptic for the patients | Drug: hypochlorous acid<br>* Randomize<br>* Other names: povidone iodine;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The effect of both drugs on wound healing will be investigated. | there is wound healing;1,no wound healing:0 | one month | 
| The effect of both drugs on antibacterial effects will be investigated | there is bacterial growth:1, there is no bacterial growth:0 | one week | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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circumcision,, wound, antibacterial