Management of Women With BRCA1/2 Mutation

Study Overview
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Brief Summary
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The aim of this study is to determine general practitionners' role in management of women with BRCA1/2 mutation. This study will be conduct between April 2017 and December 2017 at Montpellier University Hospital on women followed-up in the department of genetics and their general practitionners (GP). Patients and their GP will be called by the investigators and questionnaire will be given to them. Questionnaire includes questions for patients and their GP. The primary endpoint was to determine the rate of GP having sufficient knowledge of the adequate management of patients with BRCA1 / 2 mutation. Adequate knowledge includes : systematic search for a family history of cancer, knowing criteria required to refer women in oncogenetic department, and the ability to respond to patients' questions. Secondary endpoint was to determine women' opinion on their GP : whether or not well managed for their BRCA 1 / 2 mutation.

Detailed Description
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PURPOSE: The aim of this study is to determine general practitionners' role in management of women with BRCA1/2 mutation. METHODS: This study will be conduct between April 2017 and December 2017 at Montpellier University Hospital on women followed-up in the department of genetics and their general practitionners (GP). Patients and their GP will be called by the investigators and questionnaire will be given to them. Questionnaire includes questions for patients and their GP. The primary endpoint was to determine the rate of GP having sufficient knowledge of the adequate management of patients with BRCA1 / 2 mutation. Adequate knowledge includes : systematic search for a family history of cancer, knowing criteria required to refer women in oncogenetic department, and the ability to respond to patients' questions. Secondary endpoint was to determine women' opinion on their GP : whether or not well managed for their BRCA 1 / 2 mutation.

Official Title
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Role of General Practionners in Management of Women With BRCA1/2 Mutation

Conditions
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BRCA1 Mutation, BRCA2 Mutation

Intervention / Treatment
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* Behavioral: Questionnaire given to the two groups


Participation Criteria
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Eligibility Criteria
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Inclusion criteria Aged over 18 Women Living in France Having a medical insurance Exclusion criteria Men Dementia Non frenchspeaker Mental retardation Being the subject of a guardianship or tutelage measure

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients with BRCA ½ mutation<br>Women with BRCA 1 / 2 mutation with or without cancer Age over 18 | Behavioral: Questionnaire given to the two groups<br>* Questionnaire given to the two groups : Patients with BRCA ½ mutation GP<br>|
| GP<br>GP of the patients with BRCA 1 / 2 mutation | Behavioral: Questionnaire given to the two groups<br>* Questionnaire given to the two groups : Patients with BRCA ½ mutation GP<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The rate of GP having sufficient knowledge of the adequate management of patients with BRCA1 / 2 mutation. | Adequate knowledge includes : systematic search for a family history of cancer, knowing criteria required to refer women in oncogenetic department, and the ability to respond to patients' questions | 1 day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Women' opinion on their GP | Women' opinion on their GP : whether or not well managed for their BRCA 1 / 2 mutation. The rate of GP wanting a formation in oncogenetic | 1 day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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BRCA1/2 Mutation, Breast cancer, General practitionner