Using of Injectable Platelet Rich Fibrin on Filling the Gap of Immediate Dental Implant

Study Overview
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Brief Summary
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The effect of using of i-PRF (injectable platelet rich fibrin) on filling the gap of immediate dental implant in the esthetic zone

Detailed Description
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Grouping the samples: (sixteen patients was recruited from the outpatient clinic of Oral Medicine, Periodontology, Diagnosis and Radiology Department, Faculty of Dentistry, Ain Shams University). The sixteen patients assigned to group 1 or group 2 will be randomly allocated using flip of a coin into one of the 2 treatment modalities. Primary objective: Radiograhic evaluation of the effect of i-PRF on filling the buccal gap distance between the immediately placed dental implant and the surrounding bone. Secondary objective: Esthetic evaluation of the effect of i-PRF on the soft tissue around immediately placed dental implant.

Official Title
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The Effect of Using of Injectable Platelet Rich Fibrin on Filling the Gap of Immediate Dental Implant in the Esthetic Zone

Conditions
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Bone Loss

Intervention / Treatment
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* Other: injectable platelet rich fibrin


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Healthy adult patient. Age from 20-50 years old Patients must be free of any systemic disease which could influence the surgical procedure. Tooth involved in the esthetic zone. Sufficient hard and soft tissue volume in vertical and buccolingual 6. Natural teeth adjacent to the involved tooth were required to be free from infection. Controlled oral hygiene. Indication for tooth extraction included; Endodontic failures Untreatable caries> Non- restorable teeth Vertical root fracture Remaining roots The decision to proceed with the implant placement was made after tooth extraction and probing of the extraction socket which revealed: The presence of intact facial bone. Compliance with all requirements in the study and signing the informed consent. Exclusion Criteria: Patient had surgeries in the same site during the last 6 months prior to the surgery. Severe vertical bone loss (socket type lll or type lV). Presence of acute dento-alveolar infection or periodontal affected of involved tooth. Pregnant and lactating females. Smokers.

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Group I (study group)8 patients undergo flapless single immediate implant placement surgery with filling the gap distance with i-PRF& bone graft Group II (control group) 8 patients undergo flapless single immediate implant placement surgery with filling the gap distance with bone graft
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: injectable platelet rich fibrin group<br>8 patients undergo flapless single immediate implant placement surgery with filling the gap distance with i-PRF& bone graft | Other: injectable platelet rich fibrin<br>* biologic activator<br>|
| No Intervention: no injectable platelet rich fibrin group<br>8 patients undergo flapless single immediate implant placement surgery with filling the gap distance with bone graft | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Radiograhic evaluation of the effect of i-PRF on filling the buccal gap distance between the immediately placed dental implant and the surrounding bone. | density, vertical and horizontal assessment of labial plate | 6 months follow up | 
| Radiographic analysis | vertical assessment of labial plate | 6 months follow up | 
| Radiographic analysis | density of labial plate | 6 months follow up | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Esthetic evaluation of the effect of i-PRF on the soft tissue around immediately placed dental implant | pink esthetic score | 6 months follow up |