Resting State Electroencephalogram for Psychotic Disorders

Study Overview
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Brief Summary
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Electroencephalography (EEG) has been proposed as a neurophysiological biomarker to delineate psychotic disorders. Meanwhile, the increased appetite, which might related to self-control process, has been an increasing concern for the management of psychotic disorders. In this cross-section study, investigators collect the resting state EEG data, self-control related scale, eating behaviour questionnaire and psychotic syndrome related assessement and try to find the connection between those measurers, in order to provide novel understanding on the mechanism of psychotic diseases.

Official Title
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Self-control, Appetite and Psychotic Diagnose: a Resting State EEG Cross Section Study

Conditions
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Schizophrenia, Bipolar Disorder, Depression

Intervention / Treatment
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* Other: No intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Diagnosed with schizophrenia or bipolar disorder or MDD in accordance with DMS-5 Informed Consent Exclusion Criteria: Diagnosed with other mental disease in accordance with DSM-5 Comorbid with other severe physiological disease Drug or alcohol abuse Pregnant or lactating

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 40 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Schizophrenia patients<br>patients who diagnosed with schizophrenia in accordance with DSM-5 criteria | Other: No intervention<br>* No intervention<br>|
| Bipolar disorder patients<br>patients who diagnosed with bipolar disorder in accordance with DSM-5 criteria | Other: No intervention<br>* No intervention<br>|
| Depression patients<br>patients who diagnosed with major depression disorder in accordance with DSM-5 criteria | Other: No intervention<br>* No intervention<br>|
| Health control<br>health participants who have not diagnosed with any psychological or psychiatric disease. | Other: No intervention<br>* No intervention<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| resting state EEG | resting state electroencephalography | baseline | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Three factor eating questionnaire | min value 21, max value 84. The higher scores mean more unhealthy eating behavior. | baseline | 
| Barratt Impulsivity Scale | min score 26, max score 104. The higher score means more impulsive. | baseline | 
| Self-Control Scale | min score 36, max score 180. The higher score means less self control. | baseline | 
| The positive and negative syndrome scale | min score 30, max score 210. The higher score means more severe symptoms. | baseline | 
| Hamilton anxiety rating scale | min score 14, max score 56. The higher score means more severe anxiety symptom | baseline | 
| Hamilton depression rating scale | min score 17, max score 68. The higher score means more severe depressive symptom | baseline | 
| Young manic rating scale | min score 0, max score 60, the higher score means more severe manic syndrome. | baseline | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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electroencephalography, Eating behavior, self control