Effect of CPAP Treatment on the Elderly With Mild to Moderate Sleep Apnea

Study Overview
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Brief Summary
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Objective: To analyze the impact of CPAP treatment on cognitive, clinical and quality of life domains in patients over 70 years of age with mild-to-moderate OSA Primary Outcome: Epworth scale and QSQ domains Secondary Outcomes: Neurocognitive variables and CPAP adherence

Official Title
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Effect of CPAP Treatment on the Elderly With Mild to Moderate Sleep Apnea

Conditions
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Unrecognized Condition

Intervention / Treatment
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* Other: CPAP


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age equal or greater than 70 years of both sexes Patients with sleep study results with AHI ≥ 15 and < 30 Exclusion Criteria: Alternative diagnoses of other non-respiratory sleep disorders that are also cause of pathological somnolence (eg, sdr restless legs, narcolepsy, etc.) Don't sign informed consent Acute or chronic respiratory insufficiency requiring home oxygen therapy Patients with Obesity Hypoventilation Syndrome Diagnosis of neuro-psychiatric diseases with the exception of anxiety - depression or diagnosis of dementia. Diseases of any origin in the acute phase Heart failure or recent stroke (less than 3 months). Central SAHS (more than 50% of the registry with central apneas or Cheyne-Stokes breathing) Pre-treatment with CPAP Inability to perform the diagnostic study of sleep due to the patient's condition Hipersomniaincapacitante (Epworth≥18) with no known or most likely cause related to SAHS

Ages Eligible for Study
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Minimum Age: 70 Years
Maximum Age: 100 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Randomized clinical trial
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Treatment CPAP<br>A group treated with CPAP | Other: CPAP<br>* This is a randomized study where patients are included consecutively under a randomization order that will be given to the investigators. Patients will continue to be treated with CPAP and other treatment with no CPAP for a duration of 3 months and with intention-to-treat analysis And by protocol.<br>|
| Sham Comparator: group without treatment<br> | Other: CPAP<br>* This is a randomized study where patients are included consecutively under a randomization order that will be given to the investigators. Patients will continue to be treated with CPAP and other treatment with no CPAP for a duration of 3 months and with intention-to-treat analysis And by protocol.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Epworth Sleepiness Scale | Measure of diurnal sleepiness | 3 months | 
| Quebec Sleep Questionnaire domains | Quality of Life measured in sleep apnea patients | 3 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Sleep apnea, Elderly, CPAP