Study of Home-Based Exercise to Alleviate Postpartum Depression

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to evaluate the effectiveness of an aerobic home-based exercise program for the treatment of postpartum depression.

Detailed Description
-----------------
Postpartum depression occurs in 10-16% of women, with depressive symptoms lasting up to one year post delivery. Women affected by depression in the postpartum have been shown to be at higher risk for developing a recurrent depressive disorder. While the direct and indirect costs associated with postpartum depression are unknown, those associated with depression have been found to exceed 43 billion dollars in the United States alone. Moreover, maternal depression can negatively impact the mother-infant relationship and infant development. Despite the high prevalence of postpartum depression, the condition often goes undiagnosed and untreated by primary care providers. Alternative non-medical interventions for treating postpartum depression have not been widely investigated, leaving women and health care providers with few evidence-based options for treatment. If this exercise program is shown to be effective, then this intervention can be an alternate treatment option for alleviating depressed mood for women in the postpartum period. This nonpharmacological approach may be particularly attractive as many women are reluctant to take medication in the postpartum.

Official Title
-----------------
Decreasing Health Care Utilization With Alternative Approaches for the Treatment of Depression: A Randomized Trial of Exercise for Postpartum Depression

Conditions
-----------------
Postpartum Depression

Intervention / Treatment
-----------------
* Behavioral: Moderate-intensity Exercise


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: women 4 to 38 weeks following childbirth score of 10 or more on the Edinburgh Postpartum Depression Scale understand English or French no current alcohol or substance abuse, not currently participating in regular moderate or high intensity exercise (30 minutes, at least 3 times per week) Exclusion Criteria: obstetrical or concomitant diseases which would have precluded participation in an exercise program.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: Moderate-intensity Exercise|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in depressed mood scores immediately following the 3 month intervention and at 3 and 6 months post-treatment, |  |  | 
| as measured by the Edinburgh Postnatal Depression Scale and the Hamilton Rating Scale for Depression. |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes in fatigue levels (measured by the multidimensional fatigue inventory), sleep patterns, anxiety and health status. |  |  | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
exercise, postpartum depression