Postoperative Analgesia Using Ganglion Impar Block After Anal Surgery

Study Overview
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Brief Summary
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The aim of this study is to evaluate the ganglion Impar block in the prevention of postoperative pain after anal surgery.

Detailed Description
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Postoperative analgesia using ganglion Impar block after anal surgery Introduction Ganglion Impar block may be used for treatment of chronic perineal pain (1) Aim The aim of this study is to evaluate the ganglion Impar block in the prevention of postoperative pain after anal surgery. Patients and Methods After approval of local ethical committee and patient consent, this double blinded randomized study will be done on 60 patients undergoing hemorrhoidectomy surgery in Alexandria University hospital. After standard general anesthesia with Propofol 1-2mg/kg LMA for airway management and maintenance with Isoflurane 1%. The patient will be randomized into two groups. Bupivacaine group; Ganglion Impar will be blocked using G25 Quinqe spinal needle using Bupivacaine 0.5% 10ml. Saline group; Ganglion Impar will be blocked using G25 Quinqe spinal needle using Normal Saline 10ml Postoperative VAS will be measured each 1 for the first 6 hours then at 9 and 12 hours postoperative. First request of pain medications will be measured. Results Results will be collected in tables and graphs. Appropriate statistical analysis will be done. Discussion Results of the study will be discussed compared to other studies.

Official Title
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Postoperative Analgesia Using Ganglion Impar Block After Anal Surgery

Conditions
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Postoperative Pain

Intervention / Treatment
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* Procedure: Ganglion impar block with Bupivacaine.
* Procedure: Ganglion impar block with normal saline


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients undergoing hemorrhoidectomy surgery in Alexandria University hospital. Exclusion Criteria: Coagulation effects Allergy to Bupivacaine Previous anal surgery Patient refusal

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: After approval of local ethical committee and patient consent, this double blinded randomized study will be done on 60 patients undergoing hemorrhoidectomy surgery in Alexandria University hospital. After standard general anesthesia with Propofol 1-2mg/kg LMA for airway management and maintenance with Isoflurane 1%. The patient will be randomized into two groups. Bupivacaine group; Ganglion Impar will be blocked using G25 Quinqe spinal needle using Bupivacaine 0.5% 10ml. Saline group; Ganglion Impar will be blocked using G25 Quinqe spinal needle using Normal Saline 10ml
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Ganglion impar block with Bupivacaine.<br>Bupivacaine group; Ganglion Impar will be blocked using G25 Quinqe spinal needle using Bupivacaine 0.5% 10ml. Patient will have hemorrhoidectomy. | Procedure: Ganglion impar block with Bupivacaine.<br>* Bupivacaine group; Ganglion Impar will be blocked using G25 Quinqe spinal needle using Bupivacaine 0.5% 10ml. Postoperative VAS will be measured each 1 for the first 6 hours then at 9 and 12 hours postoperative.<br>|
| Placebo Comparator: Ganglion impar block with Saline<br>Saline group; Ganglion Impar will be blocked using G25 Quinqe spinal needle using Normal Saline 10ml Patient will have hemorrhoidectomy. | Procedure: Ganglion impar block with normal saline<br>* Saline group; Ganglion Impar will be blocked using G25 Quinqe spinal needle using Normal Saline 10ml Postoperative VAS will be measured each 1 for the first 6 hours then at 9 and 12 hours postoperative.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative pain | VAS sore 0-10 | 24 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| First request of pain medications will be measured. | Time in hours | 24 hours |