Interval Versus Continuous Training in Healthy Adults

Study Overview
=================
Brief Summary
-----------------
Aerobic exercise produces increases in cardiorespiratory fitness (CF), which constitute a protective factor for cardiovascular disease and all-cause mortality. Therefore, aerobic exercise is a key strategy to promoting cardiovascular. There is some evidence that aerobic high intensity interval training may lead to greater increases in CF compared with continuous moderate-intensity training. The main objective of this study is to examine the effects of an aerobic high intensity training program versus a continuous moderate intensity training program on CF in men 18 to 44 years.

Detailed Description
-----------------
Forty-four individuals will be randomly assigned to one of two aerobic training programs on a treadmill. Both groups will performed three times a week for eight-weeks (on alternate days). Half will run 40 minutes of continuous exercise at an intensity between 65-75% of maximum heart rate, and the remaining 22 will complete 21.5 minutes of interval exercise at an intensity between 90-95% of maximum heart rate, with recoveries between 50-55 % of maximum heart rate. After each session both groups will complete eight strength exercises mainly including large muscle groups for two sets and 8-12 repetitions at an intensity equivalent to 60-70% of one repetition maximum (controlled by perceived effort). Rest between sets will be kept between 60 and 90 seconds. All participants will be evaluated at the start and completion of the intervention for their maximal oxygen consumption, blood pressure, waist circumference, BMI, body composition, and steps per week.

Official Title
-----------------
Effects of a High-intensity Interval Training Program Compared to a Moderate Intensity Program in Adults 18-44 Years

Conditions
-----------------
Healthy Volunteers

Intervention / Treatment
-----------------
* Behavioral: Aerobic interval training
* Behavioral: Continuous training


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Perform aerobic exercise maximum 3 sessions per week Exclusion Criteria: Currently participating in an aerobic high intensity training program Smoker History of cardiovascular disease History of coronary heart disease Arrhythmias Heart failure/insufficiency Hypertension Diabetes Under medical treatment with anticoagulants, beta-blockers, calcium antagonists, bronchodilators, and/or steroids Psychological, neuromotor and/or osteo-muscular conditions that may affect participation in an exercise program.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 44 Years

Sexes Eligible for Study
-----------------
Male

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Aerobic interval training<br>Interval exercise at an intensity between 90-95% of maximum heart rate (15x30 s), with recoveries at an equivalent speed to 50-55 % of maximal oxygen consumption at baseline (14x60 s). 24 training sessions, 3x weekly (on alternate days). | Behavioral: Aerobic interval training<br> <br> |
| Active Comparator: Continuous training<br>40 minutes of continuous exercise at an intensity between 65-75% of maximum heart rate. 24 training sessions, 3x weekly (on alternate days). | Behavioral: Continuous training<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in maximal oxygen uptake |  | Baseline and 8-weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in systolic blood pressure |  | Baseline and 8-weeks | 
| Change in diastolic blood pressure |  | Baseline and 8-weeks | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Aerobic Exercise, Oxygen Consumption, Blood Pressure