Advanced HIV Prevention (PrEP Chicago)

Study Overview
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Brief Summary
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This study will evaluate the feasibility of a network intervention to train individuals to disseminate PrEP information and motivate initial PrEP interest and knowledge of PrEP in their social networks.

Detailed Description
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The specific aims of this study are: To recruit 450 participants in Chicago, Illinois, and to train them as peer change agents (randomized to cross-over groups) to disseminate PrEP information and motivate PrEP interest and knowledge of PrEP in their local networks. To evaluate feasibility of the program over 2 years of participant follow-up through: 1) peer change agent exit survey; 2) peer change agent booster sessions; 3) peer change agent communication with University of Chicago PrEP program social media; 4) referrals into the project and; 5) calls into the PrEP warmline.

Official Title
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Advanced HIV Prevention (PrEP Chicago)

Conditions
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HIV

Intervention / Treatment
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* Behavioral: PrEP Intervention Group
* Other: Control Group


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Lives on the South Side of Chicago, Illinois Born male Has had sex with men in the previous year Is an active Facebook user Does not have plans to leave Chicago Exclusion Criteria: -

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 39 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: PrEP Intervention Group<br>Group training session including HIV Education, PrEP Education, Following the training session Booster phone calls HIv and syphillis testing | Behavioral: PrEP Intervention Group<br> <br> |
| Active Comparator: Control Group<br>Group HIV risk vignettes | Other: Control Group<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Network member call into the PrEPline |  | 2 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| PrEP Attitudes questionnaire | Monitor the change in attitude towards PrEP (1) from baseline measure to 12-months; (2) 12-months to 24-months; and (3) baseline to 24-month. | 2 years | 
| Peer change agent boosters sessions completed |  | 2 years | 
| Number of Facebook posts with respect to PrEP and sexual health |  | 2 years | 
| Number of referrals enrolled into the study |  | 2 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Pre-exposure prophylaxis (PrEP), diffusion of innovation, men who have sex with men, LGBT, African American, Black, HIV, network analysis, network intervention