Two Different Surgical Techniques for the Treatment of Multiple Gingival Recessions With Porcine Collagen Matrix

Study Overview
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Brief Summary
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The gold standard for gingival recession treatment is the coronal repositioning of the flap associated with the subepithelial connective tissue graft. The porcine collagen matrix (PCR) has been used as a substitute for subepithelial connective tissue graft in periodontal plastic surgery and has achieved similar results. The PCR use has the advantage of avoiding possible pre and postoperative complications , as well as overcome the limitations presented by autograft . The different surgical techniques used for root coverage seek predictability and success . For this, besides the type of incision placements flap and graft are the most important because the healing benefits and outcome . The aim of this study is to compare two surgical techniques for root coverage and evaluate which one provides better clinical outcomes and less morbidity . 20 adults , nonsmoking patients , showing multiple bilateral gingival recessions , class I or II Miller located in canine, first and second premolars are selected. Both techniques use the PCR as a graft . However, in one Quadrant partial flap will be held together with relaxing incisions through an intrasulcular incision, PCR will be positioned 1 mm apical to the cementoenamel junction (CEJ) and the flap will be positioned 1 mm coronal CEJ. In the opposite quadrant periosteal envelope that does not use relaxing incisions, avoiding any scars, will be performed with the PCR. The clinical parameters (gingival recession height and width, keratinized tissue thickness and width) will be evaluated 2 weeks after basic periodontal therapy and after 6 and 12 months to surgical procedures..

Official Title
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Clinical Comparison Between Two Surgical Techniques for the Treatment of Multiple Gingival Recessions With Porcine Collagen Matrix

Conditions
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Gingival Recession, Xenograft Model, Gingival Recession, Generalized

Intervention / Treatment
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* Procedure: tunnel technique for Root coverage with Porcine collagen Matrix
* Procedure: extended fla technique for Root coverage with Porcine collagen Matrix


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: -bilateral multiple gingival recession type Miller class I or II with at least one tooth with 3 mm of gingival recession height Exclusion Criteria: diabetics pregnant women chronic use of medication periodontitis smokers

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Single Group Assignment
Interventional Model Description: Split Mouth clinical trial, comparing two different techniques. One side, the tunnel technique will be performed and on the other side, extended flap will be performed. Both surgical techniques will use Porcine Collagen Matrix.
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Test Group (tunnel technique)<br>It Will be performed root coverage of multiple recessions using porcine collagen matrix with a tunnel Technique | Procedure: tunnel technique for Root coverage with Porcine collagen Matrix<br>* Tunnel technique for root coverage for multiple gingival recessions, using porcine collagen matrix<br>* Other names: mucograft matrix;|
| Placebo Comparator: Control Group (extended flap technique)<br>It Will be performed root coverage of multiple recessions using porcine collagen matrix with a extended flap technique | Procedure: extended fla technique for Root coverage with Porcine collagen Matrix<br>* Extended flap technique for root coverage for multiple gingival recessions, using porcine collagen matrix<br>* Other names: mucograft matrix;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Root coverage (milimeters) | Root Coverage is measured by the difference between Gingival Recession Hight at baseline and 12 months | baseline, 6 and 12 motnhs | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Keratinized tissue (milimeters) | Keratinized tissue is measured by its width and thickness. | baseline, 6 and 12 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Gingival recession, porcine collagen matrix, multiple gingival recessions, tunnel technique