Evaluation of Energy Expenditure, Body Composition and Recovery Rates in Children With Severe Acute Malnutrition

Study Overview
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Brief Summary
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This project is being conducted with an aim to find out energy expenditure, body composition and recovery rates in children with severe acute malnutrition (SAM) receiving community-based nutritional rehabilitation therapy

Detailed Description
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Objectives To assess energy expenditure and body composition by stable isotope techniques in children with Severe Acute Malnutrition To evaluate the potential usefulness of body composition assessment as a predictor of outcome in children with SAM, based on stable isotope technique and multi-frequency bioelectrical impedance analysis (BIA) Inclusion criteria Parents of children of age 6 months to 3 years Resident of study area Exclusion criteria Children with congenital malformations Chronic debilitating illnesses Refusal by parents to enroll in study

Official Title
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Evaluation of Energy Expenditure, Body Composition and Recovery Rates in Children With Severe Acute Malnutrition (SAM) Receiving Community-based Nutritional Rehabilitation Therapy

Conditions
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Children, Malnutrition

Intervention / Treatment
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* Behavioral: Nutrition education
* Dietary Supplement: RUTF


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Parents of children of age 6 months to 3 years Resident of study area Exclusion Criteria: Children with congenital malformations Chronic debilitating illnesses Refusal by parents to enroll in study

Ages Eligible for Study
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Minimum Age: 6 Months
Maximum Age: 3 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Group 1<br>Parent/care givers of children with severe malnutrition in enrolled in this group will be given nutrition education using the principles of infant and young child feeding (IYCF) and dietary diversification | Behavioral: Nutrition education<br>* Parent/care givers of children with severe malnutrition in enrolled in this group will be given nutrition education using the principles of infant and young child feeding (IYCF) and dietary diversification<br>|
| Active Comparator: Group 2<br>Ready to use therapeutic food (RUTF / PlumpyNut)will be provided to parent/care givers of children with severe malnutrition in enrolled in this group | Dietary Supplement: RUTF<br>* Ready to use therapeutic food (RUTF / PlumpyNut) will be provided to the parent/care givers of children with severe malnutrition in enrolled in this group<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Body composition |  | 12 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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SAM, RUTF, BIA, D2O, Children with severe malnutrition