Creation of a Monocentric Cohort of Patients Treated for Acne at the Nantes University Hospital

Study Overview
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Brief Summary
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With 24 million results associated with Google's searchon keywords severe acne, Pr Dreno's team understand better thatthis disease, which affects many French people, is a real concern of Public Health and not a forced evil of the adolescent period, which will eventually resolve itself. Acne does not affect the vital prognosis, but its psychosocial impact is major and should not be underestimated. Paradoxically, despite the high prevalence of acne, few quality epidemiological studies have been published. Physicians are often helpless when faced with patients' questions. They often need a lot of explanations, especially on the factors aggravating this dermatosis, which greatly affects their quality of life. This cohort, the first of its kind in France, will determine the predictive factors of therapeutic response, endogenous and environmental factors impacting on the severity of acne assess the quality of life and psychological impact of acne patients, determine the patient's course of care and the associated costs. Pr Dreno's team will also build up a bio collection (bacteriological samples).

Detailed Description
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All patients going for the first time in specialized consultation acne at Nantes University Hospital , and who meet the inclusion criteria will be included in the COPACNE cohort. Inclusion will take place at the first consultation, after information and agreement of the patient and, if applicable, his or her legal representatives. The frequency of each patient's follow-up visits will be determined on a case-by-case basis according to the patient's medical needs (generally, the interval between 2 visits is between 1 and 4 months).

Official Title
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Creation of a Monocentric Cohort of Patients Treated for Acne at the Nantes University Hospital: the COPACNE Cohort.

Conditions
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Acne

Intervention / Treatment
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* Other: acne


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patient with acne Patient (or parents/guardians for minors) who are not opposed to participating in the cohort. Subjects affiliated to an appropriate health insurance Exclusion Criteria: Dermatosis of the face other than acne Refusal to participate by the minor or parent/guardian Adults under a legal protection regime (guardianship, trusteeship, judicial safeguard)
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: acne|Patient with acne|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Measure of Acne stage | composite criteria. the scale is GEA for Global Evaluation Acne Scale with 0 no acne to 5 severe acne | 2 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| assessing patients' quality of life | composite criteria. CADI score is calculated by summing the score of each question resulting in a possible maximum of 15 and a minimum of 0. The higher the score, the more the quality of life is impaired. | 2 years | 
| cost of acne illness | reimbursement data relating to hospitalizations and care in town recorded by the Health Insurance in the SNIIRAM database. | 2 years | 
| Bacteriological sample to find Propionibacterium acnes, Hormonal check-up on blood sample | Correlation between bacterial and blood samples and the efficacity of the treatment | 2 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Acne, Cohort, prospective, risk factors