Comparative Effects of Aerobic Exercises, Resistance Training and Combined Training on Heart Failure Patients

Study Overview
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Brief Summary
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To compare the effectiveness of aerobic training and resistance training and combined training on heart failure patients.

Official Title
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Comparative Effects of Aerobic Exercises, Resistance Training and Combined Training on Heart Failure Patients

Conditions
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Heart Failure

Intervention / Treatment
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* Other: Aerobic exercises
* Other: Resistance exercises
* Other: Combined training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Heart failure patients with ejection fraction greater than 35% Exclusion Criteria: Patients with unstable angina Patients who had severe pain in the lower limbs Patients with Blood pressure greater than 190/120mmHg were excluded Patients who had positive contraindication for cardiac rehabilitation were not admitted in this study

Ages Eligible for Study
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Minimum Age: 35 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Aerobic exercises<br>Treadmill and Cycle ergometer | Other: Aerobic exercises<br>* For Week 1 and 2 : Treadmill 3-5days/weeks Intensity: 50-70 vo2 peak Or HRR 60-80% Duration of 10-20 minutes For Week 3 and 4; Cycle ergometer 3-5days/weeks Intensity: 50-70 vo2 peak Or HRR 60-80% Duration of 30-40 minutes<br>|
| Experimental: Resistance exercises<br>unilateral leg press, Bilateral leg press, unilateral arm curls | Other: Resistance exercises<br>* For Week 1 and 2; 2 x 10 rep (unilateral leg press) 4x 12 reps (Bilateral leg press 1 x 8 rep ( unilateral arm curls For Week 3 and 4; 1 x 10 reps Shoulder press 1 x15 rep Bilateral knee extension 1 x 10 reps Bilateral arm curls<br>|
| Experimental: Combined training<br>Treadmill and Cycle ergometer along with resistive Training | Other: Combined training<br>* For Week 1 and 2; Aerobic exercise on Treadmill along with dumbbell to perform upper limb exercises (biceps curls, side curls extensions, upright row, back fly) and used Thera band to perform lower limb exercises for 10-20 minutes For Week 3 and 4; Aerobic exercise on Treadmill along with dumbbell and Thera band to perform upper limb and lower limb exercises for 30-40 minutes<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Hospital Anxiety and Depression Scale | Hospital Anxiety and Depression Scale (HADS) is a 14-item scale with seven items each for anxiety and depression subscales. Scoring for each item ranges from zero to three. A subscale score >8 denotes anxiety or depression. Changes from the Baseline will be measured. | 4th week | 
| Minnesota living with heart failure questionnaire | Minnesota living with heart failure questionnaire (MLHFQ) is a self-administered, 21-item disease-specific instrument for patients with heart failure. MLHFQ is an instrument which has been widely used to assess quality of life among heart failure patients. Each item is scored in a 6-point Likert Scale (0 to 5), thus the total score could range from 0 to 105, with higher scores indicating more significant impairment in health-related quality of life. The MLHFQ has two domains; physical domain (eight items, score range from 0 to 40) and emotional domain (five items, score range from 0 to 25). Changes from the Baseline will be measured | 4th week | 
| 6 Min walk test (Distance in meters) | Changes from the baseline, 6 Min Walk Distance (6 MWD) was used to measure Functional capacity. It is a sub maximal exercise test which can aid in assessing functional capacity of patients with cardiopulmonary diseases, in this test we find out the maximum distance in meters which an individual covers in 6 min without any support. | 4th Week | 
| Peak VO2 with formula | A generalized equation can be used to determined Peak rate of oxygen consumption (peak VO2). The generalized equation can be used to accurately estimate mean peak VO2 from mean 6 MWD, among groups of patients with diverse diseases without the need for cardiopulmonary exercise testing. The equation is: Mean peak VO2(ml/kg/mins) = 4.948 + 0.023*Mean 6 MWD (meter) Changes From the Baseline will be measured. | 4th Week | 
| Heart Rate/Pulse Rate | Changes from baseline, Pulse rate was measured per minute through pulse oximeter. Crossly it was measure by Chest belt (Polar Heart Rate monitors). Changes from the Baseline will be measure. | 4th Week | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Aerobic Exercises, Resistance Training, Combined Training