Effectiveness of Egg Versus Whey Protein Powder During Resistance Training

Study Overview
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Brief Summary
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Consumption of whole eggs has recently been shown to stimulate muscle protein synthesis to a greater degree than consumption of egg whites after a resistance training session. It is theorized that the egg yoke contains bio-active nutrients that enhance the protein provided by egg whites. The study will evaluate the effect of whole egg powder compared to whey protein powder and placebo over 12 weeks of resistance training in men and women who are participating in resistance training programs.

Detailed Description
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Consuming whole eggs after resistance training sessions appears to be more effective for simulating muscle protein synthesis that simply consuming egg whites. The egg yolks might enhance the effect of protein derived from egg whites. The study will compare post-exercise supplementation with about 30 grams of protein derived from whole egg powder versus whey protein powder and placebo (maltodextrin) over a 12-week resistance training program. Resistance-trained men and women (n=120) will be randomized to consume either the whole-egg powder, whey protein powder or maltodextrin after resistance training 6 times per week for 12 weeks. The primary outcome measure is change in lean tissue mass. Secondary measures include change in fat mass, change in arm and leg muscle thickness, change in bench press, squat, and knee extension strength, and change in fasting blood glucose.

Official Title
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Egg Versus Whey Protein as the Optimal Supplement for Fitness-conscious People

Conditions
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Muscle Atrophy

Intervention / Treatment
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* Dietary Supplement: Whole egg powder
* Dietary Supplement: Whey protein powder
* Dietary Supplement: Maltodextrin placebo


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Resistance training experience for at least one year Exclusion Criteria: Having taken any nutritional supplements the past 30 days Currently using anabolic steroids Currently taking corticosteroids Allergies to dairy or egg products Identifying any medical conditions as determined by the Get Active Questionnaire

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 35 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Whole egg powder<br>Dietary supplementation with whole egg powder after resistance training sessions | Dietary Supplement: Whole egg powder<br>* Nutritional supplementation during a 12 week resistance training program<br>|
| Active Comparator: Whey protein powder<br>Dietary supplementation with whey protein powder after resistance training sessions | Dietary Supplement: Whey protein powder<br>* Nutritional supplementation during a 12 week resistance training program<br>|
| Placebo Comparator: Maltodextrin placebo<br>Dietary supplementation with maltodextrin placebo after resistance training sessions | Dietary Supplement: Maltodextrin placebo<br>* Nutritional supplementation during a 12 week resistance training program<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in lean tissue mass | Lean tissue mass measured by DXA | 12 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in fat mass | Fat mass measured by DXA | 12 weeks | 
| Change in biceps muscle thickness | biceps muscle thickness measured by ultrasound | 12 weeks | 
| Change in triceps muscle thickness | triceps muscle thickness measured by ultrasound | 12 weeks | 
| Change in quadriceps muscle thickness | quadriceps muscle thickness measured by ultrasound | 12 weeks | 
| Change in hamstrings muscle thickness | hamstrings muscle thickness measured by ultrasound | 12 weeks | 
| Change in bench press strength | Bench press strength (kg) | 12 weeks | 
| Change in leg squat strength | Leg squat strength (kg) | 12 weeks | 
| Change in knee extension strength | Isokinetic knee extension torque | 12 weeks | 
| Change in fasting glucose | Fasting glucose | 12 weeks |