Smoking Cessation in Substance Abuse Treatment Patients: A Feasibility Study

Study Overview
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Brief Summary
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The purpose of this study is to compare the effects of self-help materials for smoking cessation and self-help materials for smoking cessation plus prize-based contingency management (CM), in which prize incentives are available for breath and saliva samples that indicate smoking abstinence, in substance abuse treatment patients who want to quit smoking.

Detailed Description
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The specific aims of this study are: (1) to examine the efficacy of self-help materials compared to self-help materials plus prize contingency management (CM) for smoking abstinence in substance abuse treatment patients and (2) examine the effects of smoking abstinence on substance use and substance treatment retention. To address these specific aims, cigarette smokers entering treatment for alcohol, cocaine or heroin abuse or dependence, who report daily smoking (at least one cigarette per day) for the past year, and who meet other inclusion and exclusion criteria, are randomly assigned to receive self-help materials or self-help materials plus CM. Individuals in the CM group have the opportunity to win prizes, worth on average $1, $20, or $100, when they meet smoking abstinence criteria (CO < 8ppm and salivary cotinine < 10ng/mL). Participants meet with research staff 4 times/week during Weeks 1-4, 2 times/week during Weeks 5-8 and 1 time/week during Weeks 9-12. Follow-up interviews are scheduled 1, 3 and 6 months following the smoking quit date.

Official Title
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Smoking Cessation in Substance Abuse Treatment Patients: A Feasibility Study

Conditions
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Nicotine Dependence

Intervention / Treatment
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* Behavioral: Contingency Management


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: meets diagnostic criteria for alcohol, cocaine or heroin abuse or dependence self-report daily smoking for at least the past year CO > 8ppm interested in quitting smoking while in treatment, minimum age 18 years old willing to provide names, addresses and phone numbers of individuals to assist in locating the patient for follow-up evaluations English speaking Exclusion Criteria: current use of NRT current use of bupropion serious, uncontrolled psychiatric illness (e.g., acute schizophrenia, suicide risk) dementia (Mini-mental status score of <23) currently participating in another CM study at the clinic in recovery for pathological gambling

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: Contingency Management|nan|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Percent negative CO readings |  |  | 
| Percent negative cotinine readings |  |  | 
| Longest period of continuous abstinence |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Self-reported frequency and severity of smoking |  |  | 
| Objective substance use |  |  | 
| Self-reported substance use |  |  | 
| Treatment retention |  |  | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Nicotine Dependence, Contingency Management