The Effects of Regular Eye-training With a Mobile Device on Adult Patients With AMD

Study Overview
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Brief Summary
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Data collection and observation of changes within AMD patients performing visual training on mobile devices

Detailed Description
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In the presented study a training-therapy in patients with dry AMD war evaluated. The main focus was on remote visibility and thus better handling of daily activities. Therapy with high-contrast administration is used for amblyopia in childhood. Furthermore, simulation therapy is used in hemianopsia in the adult age, in which case the lesion is usually not located in the eye. This stimulating therapy for children and adult patients led to the hypothesis that this treatment could also improve AMD's situation. The entire visual procedure also shows the possibility of change even in adult patients. The presented study investigates if regular training with a device that provides a moving grating-stimulus, the Medical Eye Trainer (MET), can improve the subjective perception of visual performance during typical activities of daily living. The aims of the study were not to show improvement of reading vision nor to show changes in the retinal structure.

Official Title
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The Effects of Regular Eye-training With a Mobile Device on Adult Patients With AMD

Conditions
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AMD

Intervention / Treatment
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* Device: Medical-Eye-Trainer (MET)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All eyes had been affected by dry AMD for 3.5 years or more Exclusion Criteria: None

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 105 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Intervention Group<br>Repetitive Training with Medical-Eye-Trainer (MET) | Device: Medical-Eye-Trainer (MET)<br>* In order to provide a high contrast, dynamic visual stimulus to the patients, we developed an app that allowed the patients to regularly train with this stimulus. The app runs on Android (version 4.2 or later). The display of the screen is divided into 4 rows. In each row, a pattern of black and white squares is moving in one direction. The directions in subsequent rows are opposite to each other. Through the movement in the opposite direction a changing pattern is achieved in vertical and horizontal extension, the pattern alternates between continuous beams and a checkered pattern. The speed of the display on the monitor is 2 cm per second. In a comfortable viewing distance (ca. 40 cm), this leads to an angular velocity of approximately 3°/sec.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual Acuity | 6 meter - Decimal | Baseline - 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Subjective Satisfaction | better - no Change - worse | Baseline - 3 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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AMD, Mobile Device, Training