Effect of Lighting Supplementation on Daytime Cognition

Study Overview
=================
Brief Summary
-----------------
The aim of the study is to examine the efficacy of supplementing sub-optimal ambient room lighting with a task lamp on working memory and procedural learning.

Official Title
-----------------
The Effect of Lighting Supplementation on Cognitive Task Performance During the Day

Conditions
-----------------
Non-visual Effects of Light

Intervention / Treatment
-----------------
* Device: Visible light


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Aged between 18-30 years; Healthy (no medical, psychiatric or sleep disorders; Non-smoking for at least 6 months; Body Mass Index of >18 or <30 kg/m2; Able to maintain 7-hour consistent sleep schedule during the study Able to refrain from caffeine, alcohol, medication and supplements during the study Exclusion Criteria: History of alcohol or substance abuse; positive result on drugs of abuse urine toxicology; Current or past history of sleep disorders, including but not limited to obstructive sleep apnea, narcolepsy, insomnia, or any significant sleep complaint Psychiatric disorder, or first degree relative with a psychiatric disorder Recent acute or chronic medical disorder Use of drugs or medication (birth control OK) likely to affect sleep, alertness or light sensitivity, as determined by the investigators Visual disorder, including but not limited to color blindness, or family history of glaucoma Pregnancy or lactation Shift work (> 2 nights / week in the last 3 months and not during the study) Transmeridian travel (2 or more time zones) in the past 3 months Any other reason as determine by the Principal Investigator

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 30 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Crossover Assignment
Interventional Model Description: Randomized crossover
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Ambient light<br>Fluorescent ambient lighting | Device: Visible light<br>* Ambient room lighting will be supplemented with additional light from a task lamp.<br>|
| Experimental: Ambient light plus task lamp<br>Fluorescent ambient lighting plus task lamp | Device: Visible light<br>* Ambient room lighting will be supplemented with additional light from a task lamp.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Working memory | Percent correct responses on a 2-minute mental arithmetic task | 8 hour light exposure | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Procedural learning | Percent change in the number of correct sequences on the Motor Sequence Task | 8 hour light exposure | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Light, Cognition, Alertness, Learning