Postoperative Course Following Wisdom Tooth Surgery

Study Overview
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Brief Summary
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The purpose of this study is to determine how quality of life changes after surgical removal of wisdom teeth

Detailed Description
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A significant percentage of patients are subjected to surgical removal of 3. molars every year. The surgical mucosal and osseous procedure may lead to postoperative discomfort including pain, for the patient. Information with respect to how patients regard the impact of this surgical treatment on oral health including pain and swelling is of great interest. More precise information about the postoperative course following this surgery will be beneficial in improving clinical treatment procedures with respect to alleviating the patients' postoperative period.

Official Title
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Postoperative Course and Quality of Life Following Surgical Removal of the Mandibular 3. Molar

Conditions
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Pain, Postoperative

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients of either sex of Caucasian origin, between the age of 18 and 45, who are candidates for surgical removal of one mandibular 3. molar Exclusion Criteria: Chronic drug treatment (except birth control medication) with analgesics, anti-inflammatory treatment (both steroidal (SAIDs) and non-steroidal anti-inflammatory drugs (NSAIDs)) apart from standard postoperative analgesic treatment administered by the operator. The necessity for anti-microbial drugs. Pregnant or lactating women. Patients with diabetes. Patients who due to age or communication skills are considered unable to complete patient forms. Professional evaluation suggests an alteration of the planned surgical area or treatment form. Surgery exceeding 45 minutes, from time of first incision to completed suturing. Known or assumed intolerance or hypersensibility to ibuprofen (standard postoperative analgesic treatment). Known or assumed intolerance or hypersensibility to the standard local anaesthetic Xylocain-adrenalin (lidocaine-adrenalin). Consumption of alcohol in the period from 2 days before or until the end of the primary observation period (postoperative days 0-7.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Females<br>Norwegian females Caucasian origin, between the age of 18 and 45, who are candidates for surgical removal of one mandibular 3. molar. | |
| Males<br>Norwegian males of Caucasian origin, between the age of 18 and 45, who are candidates for surgical removal of one mandibular 3. molar | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Oral Health Impact Profile (OHIP-14) | Measure functional status of the oral cavity | 7 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain Intensity (0-10 Numerical Rating Scale) | Subjective measure pain intensity | 7 days | 
| Norwegian McGill Pain Questionnaire (NMPQ) | Measure quantitative and qualitative pain characteristics | 7 days | 
| Norwegian Translated Short-Form McGill Pain Questionnaire (NTSF-MPQ) | Measure qualitative and quantitative pain characetristics | 7 days | 
| Subjective Swelling Assessment (0-10 Numerical rating Scale) | Subjective assessment of postoperative swelling | 7 Days | 
| Corahs Dental Anxiety Scale (CDAS) | Assessment of preoperative anxiety | 1 day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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third molar, quality of life, postoperative swelling, postoperative pain, Surgical Procedures, Operative, Postoperative Period