MeFirst: A Tailored Intervention to HPV Vaccine Decision Making

Study Overview
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Brief Summary
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This study will test whether a tailored, online educational intervention increases HPV vaccine uptake and intent among female college students.

Detailed Description
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MeFirst is the first web-based, online, educational tool designed to promote Human Papillomavirus (HPV) vaccine awareness and understanding in an effort to improve HPV vaccine intent and uptake among female university students. HPV is the most common sexually transmitted infection and causes genital warts and cancer. The HPV vaccine has been recommended for girls ages 11-26 since 2006, yet vaccination rates remain low. Tailored online interventions may be more effective tools to promote behavior change among college students than traditional static interventions. The proposed study is a randomized controlled trial testing the efficacy of the MeFirst tool vs. standard static educational material on increasing HPV vaccination intent and uptake among female university students aged 18-26.

Official Title
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MeFirst: A Tailored Intervention to HPV Vaccine Decision Making

Conditions
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Human Papillomavirus-Related Carcinoma

Intervention / Treatment
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* Behavioral: MeFirst Tailored Intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: enrolled at the University of Michigan Exclusion Criteria: receipt of any doses of HPV vaccine

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 26 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: Centers for Disease Control and Prevention (CDC) Fact Sheet<br>Participants will receive the CDC Fact sheet about HPV vaccination while they are taking the survey. | |
| Experimental: MeFirst Intervention<br>Participants will receive a tailored website regarding their own individualized risk for HPV and information about HPV Vaccination while they are taking the survey as opposed to receiving the CDC fact sheet. This tailored website is generated based on answers provided by each subject in the baseline survey. | Behavioral: MeFirst Tailored Intervention<br>* Participants will be lead through MeFirst, an interactive web-based tool that is tailored to their responses during the survey. This tool provides information regarding HPV Vaccination.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Determine the effect of the MeFirst tool, a tailored, online HPV vaccination decision-making guide, on HPV vaccination intention and/or uptake. | Intention will be assessed on a five-point scale immediately after and at 3 and 12 months. Uptake will be assessed by yes/no/don't know response to the statement, I have received at least 1 dose of the HPV vaccine at 3 and 12 months. | Immediately post intervention, 3 months and 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Determine the effect of the MeFirst tool on HPV-related knowledge. | Comparing 5 or 10-point scales measuring participants' HPV-related knowledge (HPV, HPV vaccination, and cervical cancer) immediately post-intervention and at 3 months and 12 months. | Immediately post intervention, 3 months and 12 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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tailored intervention, college aged students, HPV