Antigravity Treadmill Training on Gait Characteristics and Balance

Study Overview
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Brief Summary
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Severe burn injuries are associated with hypermetabolic responses and increased catabolism. These generalized changes lead to a vast loss of muscle mass and cause reduced muscle strength and endurance, limited walking ability, and reduced functional mobility Recently, the antigravity treadmill or lower body positive pressure (LBPP) technology has been developed as a unique system of maintaining a participant's body weight all through treadmill training and developing low-load treadmill walking using a unique treadmill system that allows gaining the benefits of low-load treadmill walking without interrupting with locomotion dynamics

Detailed Description
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Objective: This single-blind randomized controlled trial aimed to examine the effects of antigravity treadmill training on gait characteristics and balance in healed adult burned patients. Methods: Fifty-five adult burn patients were chosen to participate in this study, their ages ranged from 18 to 35 years. They were randomly allocated to Alter G (ALG) (n=22), and control (Cont) (n=23) groups. The control group received a traditional physical therapy program (TPTP), three times per week. In contrast, the experimental group received antigravity treadmill training (30 minutes,3 times/week, speed 0.1 m/sec, 75% body weight) in addition to the traditional physical therapy program given to the control group. All study participants followed the instructions recommended for the exercise performed (three days per week) in terms of intensity, type, and duration to limit any difference between groups, as well as instructions about not exercising the rest of the week. During the study period, both groups received standard medical care. outcome measures: gait characteristics and postural stability indices were measured at the baseline (pre) and end of 12 weeks of intervention (post). The Statistical Package for the Social Sciences (SPSS) software was used for statistical analysis. The Shapiro-Wilk test was used to determine the normality of the data. The paired t-test was used to test within-group comparisons of mean changes in muscle strength, gait characteristics, and postural stability indices. The unpaired t-test was used to compare between groups. P<0.05 was chosen as the level of significance.

Official Title
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Effect of Antigravity Treadmill (Alter G) Training on Gait Characteristics and Balance After Healed Adult Burns: A Randomized Controlled Trial

Conditions
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Burns

Intervention / Treatment
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* Device: Antigravity treadmill
* Other: Traditional physical therapy program


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients with circumferential lower limb deep second to third-degree thermal injury Burns extending from the lower trunk to the foot were considered The total body surface area (TBSA) ranges from 35 to 50% All patients completed the same physical therapy program during hospitalization peroid Exclusion Criteria: Lower limb prosthesis Severe musculoskeletal disorders Serious cardiovascular insult Participation in an outside physical training program Fracture Medication that negatively impacts the study's results Brain injury Vestibular disorders Visual disorders History of epilepsy

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 35 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Group 1 (ALG+TPTP)<br>Patients received Antigravity treadmill training + Traditional physical therapy program | Device: Antigravity treadmill<br>* Alter G training for 30-minute, 3 times/week, 75% body weight<br>* Other names: Traditional physical therapy program;Other: Traditional physical therapy program<br>* applied 3 times/week for 12 weeks<br>|
| Active Comparator: Group 2 (TPTP)<br>Patients received a Traditional physical therapy program | Other: Traditional physical therapy program<br>* applied 3 times/week for 12 weeks<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Gait characteristics | Stride length (cm) | at baseline and after 12 weeks | 
| Change in Gait characteristics | Step length (cm) | At baseline and after 12 weeks | 
| Change in Gait characteristics | Velocity (cm/sec) | At baseline and after 12 weeks | 
| Change in Gait characteristics | Cadence (step/mint) | At baseline and after 12 weeks | 
| Change in Gait characteristics | Double support time (sec) | At baseline and after 12 weeks | 
| Change in Postural stability indices | Medio-lateral Stability Index (MLI) | At baseline and after 12 weeks | 
| Change in Postural stability indices | Antero-posterior Stability Index (API) | At baseline and after 12 weeks | 
| Change in Postural stability indices | Overall Stability Index (OSI) | At baseline and after 12 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Burn, Gait, Balance, Antigravity treadmill