Retained Lens Fragments After Phacoemulsification

Study Overview
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Brief Summary
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The purpose of this study is to investigate postoperative events in patients noted to have retained nuclear fragments in the anterior vitreous during routine phacoemulsification and in those who did not.

Detailed Description
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In this study, we investigate whether presence of retained nuclear fragments in the anterior vitreous noted during uncomplicated cataract surgery is associated with higher incidence of postoperative adverse events. We will be assessing events including cystoid macular edema, iritis, elevated intraocular pressure, and retinal detachment.

Official Title
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Postoperative Events in Patients With and Without Retained Nuclear Fragments in the Anterior Vitreous After Routine Phacoemulsification

Conditions
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Cataract

Intervention / Treatment
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* Procedure: Phacoemulsification


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Routine cataract surgery with phacoemulsification Exclusion Criteria: Pre-existing macular edema Active uveitis Intraocular exclusion surgeries Significant ocular trauma Evidence of phacodonesis or zonular weakness .

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Cataract Phacoemulsification<br>Subjects will be recruited serially from eligible candidates on the basis of presentation for cataract evaluation and subsequent cataract surgery with phacoemulsification. | Procedure: Phacoemulsification<br>* Subjects will be recruited serially from eligible candidates on the basis of presentation for cataract evaluation and subsequent cataract surgery with phacoemulsification.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Macular edema | Proportion of eyes with clinical macular edema and subclinical macular edemas measured by OCT at 1 month postoperatively | 1 month postoperatively | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Intraocular inflammation | Proportion of eyes with persistent anterior chamber inflammation requiring medical treatment at 1 month postoperatively | 1 month postoperativley | 
| Elevated intraocular pressure | Proportion of eyes with intraocular pressure increase requiring medical or surgery treatment at 1 month postoperatively | 1 month postoperatively | 
| Macular Edema | Proportion of eyes with clinical macular edema and subclinical macular edemas measured by OCT at 1 week postoperatively | 1 week postoperatively | 
| Intraocular Inflammation | Proportion of eyes with persistent anterior chamber inflammation requiring medical treatment at 1 week postoperatively | 1 week postoperatively | 
| Elevated Intraocular Pressure | Proportion of eyes with intraocular pressure increase requiring medical or surgery treatment at 1 week postoperatively | 1 week postoperatively | 
| Macular Edema | Proportion of eyes with clinical macular edema and subclinical macular edemas measured by OCT at 3 months postoperatively | 3 months postoperatively | 
| Intraocular Inflammation | Proportion of eyes with persistent anterior chamber inflammation requiring medical treatment at 3 months postoperatively | 3 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Retained nuclear lens fragments, Phacoemulsification, Cataract Surgery