Study of Influenza Virus Infection in Children Hospitalized in Spain in Two Consecutive Influenza Seasons

Study Overview
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Brief Summary
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This is an epidemiological, retrospective and observational study, by reviewing clinical histories, of children hospitalized for influenza virus infection, their comorbidities and the treatments that have been performed

Detailed Description
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A better knowledge in our environment of the characteristics of the Influenza virus infection in the pediatric age, the clinical aspects, risk factors, the evolutionary and prognostic aspects, of morbidity and the direct medical costs, can allow a better management of the disease and a greater awareness of the importance of vaccination against influenza in the healthy child

Official Title
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Study of Influenza Virus Infection in Children Hospitalized in Spain in Two Consecutive Influenza Seasons. Analysis of Direct Medical Costs

Conditions
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Influenza Virus Infection

Intervention / Treatment
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* Other: Retrospective and observational epidemiological study, by review of clinical histories,


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Boys and girls under 15 years of age. With a clinical diagnosis of influenza virus infection. With infection by influenza virus confirmed microbiologically. Hospitalized more than 24 hours Exclusion Criteria: Age equal to or greater than 15 years. That the clinical diagnosis is not influenza virus infection. Influenza virus not confirmed by microbiological diagnosis. Not hospitalized or hospitalized for less than 24 hours.

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Retrospective and observational epidemiological study, by review of clinical histories,|Retrospective and observational epidemiological study, by review of clinical histories,|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To study the rate of hospitalizations for influenza virus infection in children under 15 years of age in third level hospitals in Spain. | Number of hospitalizations in children under 15 years old due to influenza virus infection | 2014-2016 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Hospitalization rate by age groups (0-6 months, 6 months to 24 months, 2 to 6 years, 6 to 10 years and 10 to 15 years of age |  | 2014-2016 | 
| Demographic characteristics of hospitalizations for influenza in children | Age, sex, weight | 2014-2016 | 
| Complications associated with influenza infection. |  | 2014-2016 | 
| Related morbidity |  | 2014-2016 | 
| Estimation of direct costs | Income costs and prescribed medication. Test costs. Bed and UCIP costs. Costs previous visits (to hospitalization) to the emergency room | 2014-2016 | 
| Epidemiological characteristics of hospitalizations for influenza in children | Presence or absence of seasonal influenza vaccination. | 2014-2016 | 
| Clinical characteristics of hospitalizations for influenza in children | Presence / absence in microbiological analysis of influenza virus. Coinfections. Presence or absence of complications during hospitalization. Variables of clinical evolution. Analytical variables. | 2014-2016 |