Transcutaneous Electrical Acupoint Stimulation(TEAS) for Hypotension After Spinal Anesthesia in Parturients

Study Overview
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Brief Summary
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The purpose of this study is to compare the effect of TEAS on hypotension after spinal anesthesia in patients undergoing cesarean section

Detailed Description
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Patients were randomly assigned to 3 groups, receiving TEAS , non-acupoint stimulation or no-stimulation after spinal anesthesia respectively. 1.4 ml of bupivacaine mixed with 0.2ml of 50% glucose was given for spinal anesthesia under lateral position. Then the patient was switched to supine position and the OR table was tilted to the left for 15 degree. The sensory loss level was assessed. The blood pressure and heart rate every 2min were recorded for 30min after spinal anesthesia. The adverse events and use of ephedrine adverse events were recorded as well.

Official Title
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Effect of Transcutaneous Electrical Acupoint Stimulation(TEAS) on the Incidence of Hypotension After Spinal Anesthesia in Patients Undergoing Cesarean Section: a Prospective, Randomized Controlled Trial

Conditions
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Hypotension

Intervention / Treatment
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* Other: TEAS
* Other: Non-acupoint stimulation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age>18yrs American Society of Anesthesiologists(ASA) status 1-2 Scheduled for elective cesarean under spinal anesthesia Gestational age>38weeks, singleton pregnancy Informed consented Exclusion Criteria: Patients with pre-eclampsia or diabetes Patients with hypertension or cardiac dysfunction Disturbance of communication Placental abruption

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: TEAS Treatment<br>Patients were given 30min of TEAS at PC6 after spinal anesthesia | Other: TEAS<br>* Electric stimulation was given through electrode attached to specific acupoints<br>* Other names: Transcutaneous electrical acupoint stimulation;|
| Sham Comparator: Non-acupoint stimulation<br>Patients were given 30min of electrical stimulation at shoulder after spinal anesthesia | Other: Non-acupoint stimulation<br>* Electric stimulation was given through electrode attached to the shoulder<br>|
| No Intervention: Control<br>No stimulation was given | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of hypotension |  | During 30min after spinal anesthesia | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Average systemic blood pressure(SBP) and diastolic blood pressure(DBP) |  | During 30min after spinal anesthesia | 
| Lowest SBP and DBP |  | During 30min after spinal anesthesia | 
| Dosage of ephedrine |  | During 30min after spinal anesthesia | 
| postoperative nausea and vomiting(PONV) score |  | During 30min after spinal anesthesia | 
| Incidence of dizzy and dyspnea |  | During 30min after spinal anesthesia | 
| Change of concentration of serum adrenaline and noradrenaline |  | Immediately after TEAS | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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hypotension, spinal anesthesia, cesarean