Chronic Effects of Tendon Vibrations on the Neuromechanical Muscular Properties.

Study Overview
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Brief Summary
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It is a randomized, controlled clinical trial, in healthy volunteers. They are in two groups : the test one will perform the vibration training (1h of Vibrasens 3 times a week, 24 sessions) whereas the control group will not be training. The primary outcome is the maximal voluntary strength.

Detailed Description
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These last 10 years, a new idea born: vibrations could have potential effects on muscular reconditioning. Researchers have previously demonstrated the effects on plantar ankle flexion, with the increase of the strength, on healthy volunteers. Nowadays physicians would like to demonstrate the effects on another muscular group: ankle's dorsal flexors. 24 sessions are programmed on 8 weeks. Moreover, the last results showed a modification of the nervous capacities of the cortical voluntary activation. Transcranial Magnetic Stimulation (TMS) is a great tool to explore the neuromuscular function, at the cortical stage. The use of this tool will allow the characterization the effects of the vibration training on the cortical activation state.

Official Title
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Chronic Effects of Tendon Vibrations on the Neuromechanical Muscular Properties : Pilot Study, Interventional, Prospective, Longitudinal.

Conditions
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Healthy

Intervention / Treatment
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* Device: Vibrasens
* Other: Usual activities


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Between 18 and 50 years old Both gender Occasional sportsman (<4h/week) Affiliated to a social security scheme Having freely given their written consent Exclusion Criteria: Taking neuro-active substances able to modify cortico-spinal excitability from Day 10 to the end of the study Contraindication to magnetic field application Previous pathologies susceptible to modify the process of the tests (particularly stakeholders presenting knee or ankle pathologies) Participation during the same time in another interventional experimentation

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Vibrasens : Test group<br>Training programme: vibration training 3/week from Day 1 to Day 60 + Usual activities from day 60 to Day 75. | Device: Vibrasens<br>* Transcutaneous vibrations are used. This device allows vibrations from 25 to 150 Hz with an amplitude of 1 mm. In our study the frequency used is 50 Hz.<br>|
| Active Comparator: Control group<br>Control: Usual activities from day 1 to Day 75. | Other: Usual activities<br>* The patients will perform their usual activities, to allow the comparison with a vibration programme. They will not have a specific training.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Increase of maximal voluntary strength in dorsal flexion of the ankle | Determine if a training of 24 sessions of tendon vibrations of dorsal flexors' ankles programmed on 8 weeks allows the increase of the maximal voluntary strength in ankles' dorsal flexion, compared to a control group, with no vibration. | 8 weeks |