Two Different Blocks for Postoperative Analgesia in Patients Undergoing Unilateral Total Knee Arthroplasty

Study Overview
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Brief Summary
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The frequency of femoral nerve block and adductor canal block for analgesia after TKA(total knee arthroplasty) increases with the use of ultrasonography in regional anesthesia. In this study, we aimed to compare the effects of femoral nerve block and adductor canal block on postoperative analgesia in patients undergoing unilateral knee arthroplasty.

Official Title
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Comparison of the Effects of Femoral Nerve Block and Adductor Canal Block on Postoperative Analgesia in Patients Undergoing Unilateral Total Knee Arthroplasty

Conditions
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Knee Replacement, Total, Pain, Postoperative, Anesthesia, Regional

Intervention / Treatment
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* Drug: Bupivacaine Injection
* Drug: Bupivacaine Injection


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: ASA(American Society of Anesthesiologists) Classification I-II Age: <55 years Unilateral total knee arthroplasty Exclusion Criteria: Does not approve the study Pregnant Emergency ASA III-IV History of local anesthetic allergy Infection in the block area Coagulation disorder Morbid obesity (body mass index> 40 kg / m²) Severe organ failure Previous neurological deficit Psychiatric disease History of chronic pain

Ages Eligible for Study
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Minimum Age: 55 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Femoral group<br> | Drug: Bupivacaine Injection<br>* Femoral nerve block with 20 ml %0.375 bupivacaine<br>|
| Active Comparator: Adductor group<br> | Drug: Bupivacaine Injection<br>* Adductor canal block with 20 ml %0.375 bupivacaine<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Tramadol consumption | Postoperative tramadol consumption with patient controlled analgesia | 24 hours after operation | 
| VAS(visual analogue scale) score (0-10, 0 is no pain, 10 is the most severe pain) | VAS(visual analogue scale) score (0-10, 0 is no pain, 10 is the most severe pain) is less than four is adequate analgesia | 24 hours after operation | 
| Rescue analgesic requirement | If VAS(visual analogue scale) score (0-10, 0 is no pain, 10 is the most severe pain) is is four or more, paracetamol 1000 mg is administered | 24 hours after operation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative nausea and vomiting | Frequency of postoperative nausea and vomiting | 24 hours after operation | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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femoral nerve block, adductor canal block, total knee arthroplasty