Effect of Electroacupuncture at Different Acupoints on Bladder Function After Spinal Cord Injury

Study Overview
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Brief Summary
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Neurogenic bladder after spinal cord injury can be divided into detrusor hyperreflexia and detrusor non reflexia. Acupuncture is recognized as a safe and effective treatment. The most commonly used acupoints are Guanyuan, Zhongji and Sanyinjiao. The purpose of this study is to clarify the therapeutic effects of different acupoints on different types of bladder. Main process: routine urodynamic examination was performed first, and then electroacupuncture was given to Guanyuan, Zhongji and Sanyinjiao points respectively, and urodynamic examination was performed again to observe the effect of Electroacupuncture on urodynamic parameters in real time.

Official Title
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Urodynamic Analysis of the Effect of Electroacupuncture at Different Acupoints on Bladder Function After Spinal Cord Injury

Conditions
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Neurogenic Bladder

Intervention / Treatment
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* Other: electroacupuncture


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients diagnosed with traumatic suprasacral SCI. the period of the spinal shock has passed. patients with voiding dysfunction after SCI. patients had stable condition, and suitable for treatment. agreed to engage in our study and sign the informed consent. Exclusion Criteria: Patients with severe primary diseases such as heart, liver, kidney, hematopoietic system, endocrine system and psychosis. dysuria caused by non spinal cord injury, such as prostatic hypertrophy, urethral obstruction, operation. Patients who have already taken cystostomy and sacral electrode implantation. Patients with urinary tract infection. Autonomic hyperreflexes were obvious. Unable to cooperate with the healer.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: sanyinjiao group<br>Perpendicular insertion about 0.8-1.2cun at bilateral sanyinjiao(SP6) acupoint.Then,bilateral SP6 were connected with Electronic Acupuncture Treatment Instrument (KWD-808-I,Yingdi, China). The frequency of the pulse was 20 Hz with a pulse duration of 200 us.Intensity of stimulus was depending on patient's tolerance. | Other: electroacupuncture<br>* electroacupuncture at Sanyinjiao (SP6)<br>|
| Active Comparator: guanyuan group<br>Perpendicular insertion about 0.8-1.2cun at bilateral Guanyuan(CV4), Zhongji (CV3) acupoints.Then,the two acupoints were connected with Electronic Acupuncture Treatment Instrument (KWD-808-I,Yingdi, China). The frequency of the pulse was 20 Hz with a pulse duration of 200 us.Intensity of stimulus was depending on patient's tolerance. | Other: electroacupuncture<br>* electroacupuncture at Sanyinjiao (SP6)<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Perianal surface electromyography | Perianal surface electromyography | Procedure (While doing acupuncture ) | 
| detrusor overactivity (DO) | detrusor overactivity in milliliter,one of the urodynamic parameters | Procedure (While doing acupuncture ) | 
| bladder compliance (BC) | bladder compliance in ml/cmH2O,one of the urodynamic parameters | Procedure (While doing acupuncture ) | 
| maximum cystometric capacity (MCC) | maximum cystometric capacity in milliliter,one of the urodynamic parameters | Procedure (While doing acupuncture ) | 
| maximum urinary flow rate (Qmax) | maximum urinary flow rate in milliliter/second,one of the urodynamic parameters | Procedure (While doing acupuncture ) | 
| maximum detrusor pressure | maximum detrusor pressure at filling stage and voiding stage | Procedure (While doing acupuncture ) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Electroacupuncture, Neurogenic Bladder, Spinal Cord Injury