Tongue Depressor-related Ischemia-Reperfusion Injury in Tongue

Study Overview
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Brief Summary
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This study aimed to detect tongue edema associated with the pressure exerted by a rigid direct laryngoscope by measuring the tongue area using USG in patients undergoing suspension laryngoscopy (SL) procedures.

Detailed Description
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Suspension laryngoscopy (SL) is a surgical procedure for both diagnostic and therapeutic purposes. In this procedure, a rigid direct laryngoscope is inserted orally, and the tongue and the base of the tongue are compressed.The tongue is an ideal organ for evaluation with ultrasonography. This study aimed to detect the occurrence of tongue edema through ultrasonography examination due to the rigid direct laryngoscope in SL procedures.

Official Title
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Is it Possible That Direct Rigid Laryngoscope-related Ischemia-Reperfusion Injury Occurs in the Tongue During Suspension Laryngoscopy as Detected by Ultrasonography: A Prospective Controlled Study

Conditions
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Side Effect, Ischemia Reperfusion Injury, Edema, Tongue Enlarged

Intervention / Treatment
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* Diagnostic Test: Ultrasonography imaging


Participation Criteria
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Eligibility Criteria
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Study group Inclusion Criteria: Patients aged 20 years or older Patients who undergo suspension laryngoscope procedure Exclusion Criteria: refusal to participate age of <20 years history of syndromal craniofacial abnormalities occurrence of tongue masses history of craniofacial surgery history of burns, trauma or radiotherapy involving the head and neck region neurologic disorders and patients with obstructive sleep apnea syndrome (OSAS) active inflammation in the head and neck region cervical rigidity limiting neck flexion and head extension Control group Inclusion Criteria: Patients aged 20 years or older Patients who did not need suspension laryngoscopy and any head and neck procedures

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Study<br>The first group is the study group. Patients aged 20 years or older and were to undergo suspension laryngoscopy procedure were eligible for inclusion in this group. Tongue areas were measured twice by submental USG. The first measurements (TA1) were done immediately after endotracheal intubation before introducing the rigid direct laryngoscope, whereas the second measurements (TA2) were done after the SL procedure and after removing the rigid direct laryngoscope just before extubation.The difference between TA2 and TA1 (i.e., TA2-TA1) were used to define the occurrence of tongue edema as study group. | Diagnostic Test: Ultrasonography imaging<br>* This study aimed to evaluate the tongue areas and compare the tongue areas before the implementation of rigid direct laryngoscope and after the rigid direct laryngoscope.<br>|
| Control<br>The second group was the control group, which included patients who did not need SL and any head and neck procedures.The tongue areas of these patients were measured twice by submental USG as in the study group. The TA1 measurements were done immediately after endotracheal intubation, whereas the TA2 measurements were done at the end of the surgical procedure just before extubation. The difference between TA2 and TA1 (i.e., TA2-TA1) were used to define the occurrence of tongue edema as study group. | Diagnostic Test: Ultrasonography imaging<br>* This study aimed to evaluate the tongue areas and compare the tongue areas before the implementation of rigid direct laryngoscope and after the rigid direct laryngoscope.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rate of change in tongue area. | This study aimed to measure the change in tongue areas before and after the implementation of rigid direct laryngoscope by using ultrasonography imaging. | 2018-2019 (6 months) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rate of formation in tongue edema. | This study aimed to measure the formation of tongue edema due to the rigid direct laryngoscope by using ultrasonography imaging. | 2018 (6 months) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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tongue, ischemia-reperfusion injury, side effect, edema, suspension laryngoscopy