Virtual Reality in COPD Exacerbation

Study Overview
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Brief Summary
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In addition to conventional pulmonary rehabilitation, virtual reality will be applied during the hospitalization period of individuals hospitalized for COPD exacerbation. It is aimed to get more efficiency from the interventions in this short time.

Detailed Description
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Subjects with COPD exacerbation will be divided two groups. Group-1 will exercise with a bicycle ergometer until fatigue in addition to pulmonary rehabilitation. Group-2 will do the same exercises. Subjects in Group-2 will use virtual reality simulation, which is designed as cycling in the forest while cycling. Treatment will continue until discharge. CAT score, mMRC dyspnea score, hospital anxiety and depression score and London chest daily living activity score will be examined before and after treatment.

Official Title
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Virtual Reality in Chronic Obstructive Pulmonary Disease: Randomized Contolled Trial

Conditions
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COPD Exacerbation, Pulmonary Rehabilitation

Intervention / Treatment
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* Device: virtual reality
* Other: conventional pulmonary rehabilitation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Individuals who are in COPD exacerbation period, FEV1 <70%, GOLD 2-3 spirometric stage, Hodkinson mental test score > 6 and who want to participate in the study voluntarily will be included in the study. Exclusion Criteria: If there is respiratory disease considered more significant than COPD (bronchiectasis, lung cancer requiring active therapy, or asthma), Heart failure New York Heart Association (NYHA) stage 3-4, Significant hemoptysis, surgical or non-surgical lung volume in the past 6 months Individuals with reduction procedures, Lung transplantation or pneumonectomy surgery in the last 6 months, pulmonary embolism or pulmonary edema, acute myocardial infarction, acute heart failure, vertigo, epilepsy and visual impairment will be excluded from the study.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Virtual reality<br>Virtual reality while cycling with ergometer in addition to conventional pulmonary rehabilitation. virtual reality designed as cylcling in the forest. | Device: virtual reality<br>* virtual reality designed as cycling in the forest<br>|
| Experimental: Conventional pulmonary rehabilitation<br>Deep diafragmatic breathing exercise, chest expansion exercies, pursed lip exhalation, coughing and huffing, upper limp exercies with deep breathing exercise, standing up-right position, cycling with ergometer. | Other: conventional pulmonary rehabilitation<br>* pulmonary rehabilitation<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 1 minute sit and stand test | performance | 5 minutes | 
| Chronic Obstructive Pulmonary Disease Assessment Test | The test assessts COPD symptoms, higher scores mean bad stiation | 3-7 days | 
| London chest activity of daily living | The test assessts dyspnea that occurs during daily living activities. The total score can range from 0 to 75 points, with higher values translating to greater limitation in activities of daily living. | 3-7 days | 
| Hospital anxiety and depression scale | The test has 2 subparameter as anxiety and depression. Each question in the test contains 4 options expressing frequency on a scale 0 to 3. Higher scores mean bad stiation for each parameter. | 3-7 days | 
| Modified Medical Research Council | The test has 5 options thas describe dyspnea. Higher scores mean higher dyspnea. | 3-7 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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COPD, pulmonary rehabilitation, virtual reality