Creation of an Ecological Tool Assessing Episodic Memory in Geriatrics

Study Overview
=================
Brief Summary
-----------------
In this study the participants can be recruited via scheduled consultation and external institutions (associations, senior club..). Neuropsychological assessment will be realize to determine presence or absence of neurodegenerative disease. Study test is ecological MAI. This test are assigned in two groups (with or without neurocognitive disorders).

Detailed Description
-----------------
In this study the participants can be recruited via scheduled consultation and external institutions (associations, senior club..). Neuropsychological assessment will be realize to determine presence or absence of neurodegenerative disease. Study test is ecological MAI. Participation will be 30 minutes for patients see in case of routine care and 2h30 for those accompanying the patients and participants recruited in external institutions. Participants are assigned in two groups. Group 1 : with neurocognitive disorders Group 2 : without neurocognitive disorders Benefits : For participants without neurodegenerative disorder, study enables to take control early if anomaly will be detected. The study permit to have cognitive assessment. Risk : It's possible that participants feel tired. No constraints for participants seen during scheduled consultation.

Official Title
-----------------
Creation of an Ecological Tool Assessing Episodic Memory in Geriatrics: an Adaptation of the Memory Test With Self-Initiated Items (MAI)

Conditions
-----------------
Memory Disorders, Neurocognitive Disorders

Intervention / Treatment
-----------------
* Diagnostic Test: ecological MAI test


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Male or female ≥ 70 ans Person have good locomotion, move independently Personne agree to participate Groupe 1 : 17≤MMSE≤24 (GRECO) Diagnosis of neurodegenerative diseases (major neurocognitive disorders: Alzheimer, mixed dementia, lobar frontotemporal degeneration, vascular dementia). Groupe 2 : MMSE ≥ à 25 (GRECO) Without neurodegenerative disease Exclusion Criteria: Person with legal protective measures Person deprived of liberty Mental retardation or MMSE≤ 16 Understanding verbal disorders Visual major disturbances Person with disease causing increased fatigue Person with psychiatric pathology excepted anxiety disorder or depression with mild episodes. Person not covered by French national health insurance

Ages Eligible for Study
-----------------
Minimum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Other
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Interventional, prospective, Study case-control
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Groupe 1 : with neurocognitive disorders<br>with neurocognitive disorders | Diagnostic Test: ecological MAI test<br>* Neuropsychological assessment will be realize to determine presence or absence of neurodegenerative disease. Study test is ecological MAI.<br>|
| Other: Groupe 2 : without neurocognitive disorders<br>without neurocognitive disorders | Diagnostic Test: ecological MAI test<br>* Neuropsychological assessment will be realize to determine presence or absence of neurodegenerative disease. Study test is ecological MAI.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To compare performance obtaining to overall score remind ecological MAI between older persons with neurocognitive disorders (groupe 1) and older persons without neurocognitive disorders (groupe 2). | Overall score remind ecological MAI test (0 to 12) in two groups. | day 1 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To compare between case and control the various dimensions of episodic memory: temporal component, space component and association component. | Spatial component is defined by localisation score. Score (0 to 12) | day 1 | 
| To compare between case and control the various dimensions of episodic memory: temporal component, space component and association component. | Temporal component is defined by temporal dimension. Score (0 to 12) | day 1 | 
| To compare between case and control the various dimensions of episodic memory: temporal component, space component and association component. | Association component is defined by binding score. Score (0 to 12) | day 1 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
GERIATRICS