linjc16/ctgov huggingface dataset:
Detection of Helicobacter Pylori Infection by High Resolution Endoscopy

Study Overview
=================
Brief Summary
-----------------
Although endoscopic findings of H. pylori have been reported in the literature, there is still some debate over whether H. pylori-related gastritis can be diagnosed via endoscopic features alone. Most studies concluded that it is not possible to diagnose H. pylori-related gastritis on the basis of endoscopic findings. However, the resolution power of endoscopy has greatly improved in recent years and the exact examination of gastric mucosa was possible.

Detailed Description
-----------------
Our study aimed to achieve the following: (1) describe the H. pylori-related mucosal pattern in the gastric corpus using high-definition endoscopy; (2) evaluate the diagnostic accuracy for H. pylori detection; (3) find the optimal biopsy site for rapid urease test (RUT); (4) validate the inter- and intraobserver agreement in the assessment of endoscopic patterns.

Official Title
-----------------
Detection of Helicobacter Pylori Infection by Non-magnifying High Resolution Endoscopy is Possible Within the Gastric Corpus

Conditions
-----------------
Helicobacter-associated Gastritis

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients who underwent upper endoscopy Exclusion Criteria: Age < 20 or > 70 Severe systemic disease or advanced chronic liver disease Medication history of NSAID, PPI, H2 blockers or antibiotics History of H. pylori eradication therapy History of gastric surgery Recent history of upper GI bleeding Gastric or duodenal ulcer (including old scar change) during endoscopy Anemia (Hemoglobin level < 10mg/dL) Pangastritis

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| H. pylori gastritis<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Diagnosis accuracy for predicting of Helicobacter pylori infection status |  | 1 day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Assessment of the clinicopathologic factors related to correct diagnosis |  | 7 days |
How Well do the Current Cesarean Deliveries Adhere to the Published ERAS Guidelines?

Study Overview
=================
Brief Summary
-----------------
Local guidelines for the postoperative care of women who have undergone cesarean delivery at the HUS/Women's hospital are based recommendations by the ERAS society. This study will take a prospective sample of 500 parturients who have gone through a cesarean delivery and their care will be verified against the local check-list for cesarean delivery.

Detailed Description
-----------------
The study will produce a snapshot of the current state of treatment in the third largest delivery hospital in Europe. The study will include cesarean deliveries in all urgency categories. The data will be collected prospectively by enrolling parturients in consecutive order from the study start date. The data will be collected in the form of a paper check list that is to be filled up by the nursing staff and doctors who are taking care of the parturient through her stay at the hospital.

Official Title
-----------------
Early Recovery After Surgery for Patients Undergoing Cesarean Delivery; Adherence to the Institutional Guideline

Conditions
-----------------
Cesarean Section Complications

Intervention / Treatment
-----------------
* Procedure: cesarean delivery


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Eligible for ERAS protocol cesarean delivery Cesarean delivery for any indication Any anesthesia method Any urgency category Exclusion Criteria: Age under 18 years

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 55 Years

Sexes Eligible for Study
-----------------
Female

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Cesarean delivery<br>Any urgency any reason | Procedure: cesarean delivery<br>* Cesarean delivery under any form of anesthesia for any reason and for any indication<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Level of adherence to the ERAS guidelines after elective or emergency cesarean delivery | To which extent does the postoperative treatment of the parturients meet the ERAS criteria | 3 days post surgery |
The Role of VitD in Rehabilitation of Idiopathic Adolescent Scoliosis

Study Overview
=================
Brief Summary
-----------------
The purpose of this current prospective study is to determine the role of vitamin D in the development and restoration of spinal deformities in adolescence.

Detailed Description
-----------------
The investigator will record the medical history of each patient and information such as age, body size (weight, height) and body mass index (BMI = kg / m ^ 2). Girls will also be given the time of appearance of menstruation, a factor that needs to be evaluated because the growth of the skeleton continues three years after its appearance. Patients will be subjected to Adam's Test, x-ray's and as well as lateral bending radiographs.In the first contact with each patient, will be evaluated bone density measured by DEXA as well as haematological testing including PTH, alkaline phosphatase (ALP), calcium (Ca), phosphorus( P ), Calcitonin and, of course, vitamin D (total and metabolite 25 (OH) D). Each patient's follow-up will be completed in two years by a clinical examination every six months and a clinical, laboratory and radiological examination per year. Patients will be divided into two groups. In a group with patients with normal 25 (OH) D and in a second group with patients with low levels of 25 (OH) D. Members of the second group will receive substitution treatment with an appropriate formulation. The results will be collected and evaluated using statistical programme.

Official Title
-----------------
The Role of VitD in Rehabilitation of Idiopathic Adolescent Scoliosis

Conditions
-----------------
Scoliosis; Adolescence

Intervention / Treatment
-----------------
* Drug: Alphacalcidol


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Idiopathic Adolescent Scoliosis Risser sign <3-4 Exclusion Criteria: Neuromuscular diseases metabolic disease Liver, lung, thyroid and parathyroid gland disorders.

Ages Eligible for Study
-----------------
Minimum Age: 10 Years
Maximum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Alphacalscidol<br>0,5mg tablet by mouth, one each day for one year | Drug: Alphacalcidol<br>* Alphacalcidol 0,5mg tablet<br>|
| No Intervention: No treatment<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 25(OH)D | Measurement of the major metabolite of vitamin D | 48 weeks | 
| X - rays | Cobb angle measurement | 48 weeks | 
| Dexa | BMD and Z - score measurement | 48 weeks | 
| BMD (weight in kilograms, height in meters) | weight and height will be combined to report BMI in kg/m^2 | 48 weeks |
Coronary Artery Study in Pediatric Heart Transplantation

Study Overview
=================
Brief Summary
-----------------
Transplant coronary artery disease (TCAD) is a significant cause of morbidity and mortality in pediatric heart transplantation (PHT). Understanding the pathophysiology and early detection along with attempted medical management are crucial in preventing advancement of the disease and retransplantation or mortality. Coronary angiogram, although routinely used is insensitive to detect early TCAD. Measurement of fractional flow reserve (FFR), coronary flow reserve (CFR) and index of microvascular resistance (IMR) using a doppler pressure and flow intracoronary wire may be more sensitive in evaluating the integrity of coronary vasculature and thus detect pre clinical TCAD. To the best of the investigators knowledge, measurement of these parameters has not been previously reported in PHT.

Conditions
-----------------
Transplant Coronary Artery Disease

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: less than 21 years and above 7 years of age Exclusion Criteria: clinically significant coronary artery disease on angiography and inability to undergo IVUS

Ages Eligible for Study
-----------------
Minimum Age: 7 Years
Maximum Age: 21 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| pediatric heart transplant recipients<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Clinical coronary artery disease |  | 1 year |
Comparative Ultrasonic Study of Post Operative Diaphragmatic Dysfunction in Abdominal and Head and Neck Surgery

Study Overview
=================
Brief Summary
-----------------
Diaphragmatic dysfunction (DD) is one of the main risk factors for post operative respiratory distress syndrome. Ultrasonography is a diagnosis tool for DD but few studies have been published. The aim of this prospective study is to compare the achievement of diaphragmatic function depending on the type of surgery (abdominal and head and neck surgery).

Official Title
-----------------
Comparative Ultrasonic Study of Post Operative Diaphragmatic Dysfunction in Abdominal and Head and Neck Surgery

Conditions
-----------------
Diaphragmatic Dysfunction

Intervention / Treatment
-----------------
* Procedure: Diaphragmatic amplitude measurement


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age>18 years Upper abdominal or head and neck surgery written consent Exclusion Criteria: Age <18 years Pregnancy History of neuropathy or myopathy, History of diaphragm paralysis, thoracic surgery, pneumothorax, pneumomediastinum

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Abdominal laparoscopic surgery (C group)<br> | Procedure: Diaphragmatic amplitude measurement<br>* Diaphragmatic amplitude is measured by M Mode ultrasonography the day before and after surgery<br>|
| Experimental: Abdominal surgery by laparotomy (L group)<br> | Procedure: Diaphragmatic amplitude measurement<br>* Diaphragmatic amplitude is measured by M Mode ultrasonography the day before and after surgery<br>|
| Experimental: Head and neck surgery (O group)<br> | Procedure: Diaphragmatic amplitude measurement<br>* Diaphragmatic amplitude is measured by M Mode ultrasonography the day before and after surgery<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Comparison of diaphragmatic amplitude measured by M-Mode ultrasonography performed the day before and the day after surgery in 3 groups: laparoscopic abdominal surgery, abdominal surgery by laparotomy and head and neck surgery. |  | two months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| All cause morbidity |  | within the first 28 days after surgery | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
diaphragmatic dysfunction, ultrasonography, respiratory distress, abdominal surgery, gender, biometric, body mass index, ASA score, smoking status, history of respiratory disease, Age
Treating Onychomychosis

Study Overview
=================
Brief Summary
-----------------
A study to treat 4 toes at a time to eliminate Onychomycosis

Conditions
-----------------
Onychomycosis

Intervention / Treatment
-----------------
* Device: Noveon laser


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 18 years or older positive onychomycosis negative pregnancy Exclusion Criteria: peripheral neuropathy

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 64 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Device: Noveon laser|Two wavelenghts of light|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Complete or near complete disappearance of toenail fungus |  | 360 days |
Effects of Eccentric Training for Shoulder Abductors in Subjects With Shoulder Impingement Syndrome

Study Overview
=================
Brief Summary
-----------------
The aim of the study was to evaluate the effect of eccentric strength training for shoulder abductors on force steadiness in subjects with subacromial impingement syndrome (SIS).

Detailed Description
-----------------
Although it is known that shoulder abduction in subjects with subacromial impingement syndrome (SIS) presents alterations in several parameters, as for example, in scapular and glenohumeral kinematics, the strengthening of the shoulder abductors as an intervention strategy is controversial in literature. Strength training has been shown to be effective in reducing the fluctuations in force and had a positive effect on isometric steadiness in old adults and in healthy young subjects during bed rest. However, there are no studies that evaluated the effects of strength training on the force steadiness in subjects with SIS.

Official Title
-----------------
Eccentric Training for Shoulder Abductors Improves Pain, Function and Isokinetic Performance Steadiness in Subjects With Shoulder Impingement Syndrome

Conditions
-----------------
Shoulder Impingement Syndrome

Intervention / Treatment
-----------------
* Device: Isokinetic eccentric training


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: subjects diagnosed with Subacromial impingement syndrome by a physical therapist (the diagnosis was confirmed by an orthopaedic physician). Exclusion Criteria: pregnancy torn rotator cuff or long head biceps tendons ligamentous laxity based on positive Sulcus test or a positive apprehension test previous shoulder or neck surgery hooked acromion systemic illnesses corticosteroid injection 3 months prior to evaluation physical therapy 6 months prior to evaluation

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 60 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Eccentric training<br> | Device: Isokinetic eccentric training<br>* The eccentric training for the shoulder abductors was performed for 6 consecutive weeks, twice a week, on alternate days.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Isokinetic evaluation |  | 2 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire |  | 2 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Subacromial impingement syndrome, Muscle Strength, Resistance Training
Vascular Endothelial Growth Factor Levels in Ectopic Pregnancy

Study Overview
=================
Brief Summary
-----------------
The aim of this study is to determine plasma Vascular Endothelial Growth Factor level and change in patient with ectopic pregnancy who needs to surgical treatment. Patient with ectopic pregnancy diagnosed and treated with medically or surgically will be included in the study. This is an observational study.The plasma Vascular Endothelial Growth Factor level will be measured first day and two day after the diagnosis of ectopic pregnancy.

Detailed Description
-----------------
This study is a prospective, observational, single-center study. Ethical approval was obtained from the Institutional Review Board. This study will be completed with 30 patients with ectopic pregnancy. An intervenous cannula will be centrifuged for 15 minutes at 1000 g within 30 minutes of collection. Aliquots of plasma will be added to eppendorf tubes and stored at -20°C. Plasma Vascular Endothelial Growth Factor levels will be measured using a Human VEGF-A Platinum ELISA kit (bioscience company, Catalog No: 00122, Santa Clara, California, USA). All assays will be performed according to the manufacturer's instructions. The test kit sensitivity is 2.5 pg/ml. Intracycle variability is %4-6, intercycle variability is %8-10.

Official Title
-----------------
Vascular Endothelial Growth Factor Levels in Ectopic Pregnancy

Conditions
-----------------
Complication Following Ectopic Pregnancy

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients who suspected ectopic pregnancy Exclusion Criteria: hemodynamically unstable patient healthy pregnancy (a healthy increase in ß HCG) missed abortion incomplete abortion The patient who need immediate surgical treatment

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 46 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Follow-up or medical treatment.<br>medical treatment | |
| Surgical treatment<br>Surgical treatment | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The primary Outcome Measure of this study is to determine plasma Vascular Endothelial Growth Factor cut-off level in patient with ectopic pregnancy who needs to surgical treatment. |  | 3-4 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
VEGF, ectopic pregnancy.
Cognitive Behavioral Smoking Cessation Intervention for Adults With Chronic Pain

Study Overview
=================
Brief Summary
-----------------
Millions of individuals with chronic pain smoke and our preliminary research suggests that currently available strategies to help people quit smoking may not be effective for individuals with chronic pain. This is important in that smokers with chronic pain have worse pain-related health outcomes compared to nonsmokers with chronic pain. The primary aim of this research project is to develop a smoking cessation intervention for specific use in an outpatient clinical setting for smokers with chronic pain.

Official Title
-----------------
Cognitive Behavioral Smoking Cessation Intervention for Adults With Chronic Pain

Conditions
-----------------
Smoking Cessation

Intervention / Treatment
-----------------
* Behavioral: Cognitive behavioral
* Behavioral: Control


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Chronic pain Age > 18 years Cigarette smoker > 10 per day Exclusion Criteria: Concurrent substance use disorder other than nicotine dependence Concurrent major psychiatric disorder

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Cognitive behavioral<br>Subjects with receive a cognitive behavioral intervention for smoking cessation | Behavioral: Cognitive behavioral<br>* Cognitive behavioral intervention for smoking cessation<br>* Other names: Smoking Cessation;|
| Active Comparator: Control<br>Treatment as usual | Behavioral: Control<br>* Treatment as usual<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The key measurement to be used to assess the effect of the experimental intervention will be the status of cigarette smoking at 6-month follow-up. | The smoking status will be determined by assessing the 7-day point prevalence use of cigarettes which is defined as the use of any cigarettes within the preceding 7 days of the follow-up date at 6-months. | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| A key secondary outcome measure will be self-report pain severity at 6-months following completion of the experimental intervention. |  | 6 month | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Smoking cessation, Nicotine dependence, Chronic pain