Ethnic Microaggressions and Smoking Behaviors Among Latinx Adults

Study Overview
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Brief Summary
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The purpose of this study is to examine whether microaggressions relate to multimodal facets of smoking behavior, subjective withdrawal, and urge/craving. Additionally, the second aim is to examine whether smoking deprivation moderates the relation between microaggressions and multiple facets of smoking behavior, subjective withdrawal, and urge/craving.

Detailed Description
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This proposal will employ a novel multi-modal approach to evaluate the role of microaggressions in relation to smoking lapse and topography among a sample of Latinx smokers. Adult Latinx daily smokers will attend two counterbalanced experimental sessions - (1) smoking deprivation (16 hours of smoking abstinence) and (2) smoking as usual - during which microaggressions during the relapse analog task will be assessed.

Official Title
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Latinx Smokers: Evaluating Ethnic Microaggressions on Smoking Behavior and Relapse

Conditions
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Smoking, Discrimination, Racial

Intervention / Treatment
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* Behavioral: Microaggression Recall and Relapse Analogue Task


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Being 18 years of age or older Current regular (daily) cigarette smoking for >= 1 year Current smoking >= 5 cig/day and biochemically confirmed via carbon monoxide (CO) analysis Being self-identified as Hispanic or Latino Able to provide written, informed consent Endorsement of at least one microaggression experience over the past 6-months Exclusion Criteria: Endorsement of current psychotic symptoms Active suicidality Currently pregnant

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Smoking Deprivation<br>16 hours of smoking abstinence prior to experimental visit. | Behavioral: Microaggression Recall and Relapse Analogue Task<br>* Participants will engage in a microaggression recall task followed by the McKee Experimental Relapse Analogue Task<br>|
| Experimental: Smoking as Usual<br>Smoking as usual prior to experimental visit. | Behavioral: Microaggression Recall and Relapse Analogue Task<br>* Participants will engage in a microaggression recall task followed by the McKee Experimental Relapse Analogue Task<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Smoking Behaviors | Smoking behaviors will be operationally defined as smoking topography (e.g., puff behavior) measured via the Clinical Research Support System (CReSS; Plowshare Technologies, Borgwaldt KC, Inc., Virginia). | During the Smoking as Usual Visit and Smoking Deprivation Visit (Visits are randomly ordered, counterbalanced separated by  14 days) | 
| Subjective Withdrawal | The 8-item Minnesota Withdrawal Scale will be used to assesses withdrawal severity. Each of the items are rated on a Likert-type scale ranging from 0 to 4. Items are summed to produce a total score with higher scores indicative of worse outcomes (possible range 0-32). | During the Smoking as Usual Visit and Smoking Deprivation Visit (Visits are randomly ordered, counterbalanced separated by  14 days) | 
| Urge/Craving | Smoking urge/craving will be measured with the 10-item Questionnaire of Smoking Urges-Brief (QSU-B). Each of the items are rated on a Likert-type scale ranging from 1 to 7. Items are summed to create two subscale scores and a total score with higher scores indicative of worse outcomes (possible range 7-70). | During the Smoking as Usual Visit and Smoking Deprivation Visit (Visits are randomly ordered, counterbalanced separated by  14 days) | 
| Smoking Lapse Behaviors | Smoking Lapse Behaviors will be measured during the Relapse Analogue Task (RAT), during which participants are able to delay smoking for a small financial reward. For this task, Smoking Lapse Behaviors are conceptualized as two variables: (a) minutes in time of smoking delay (possible range -50 to +50) and (b) number of cigarettes smoked | During the Smoking as Usual Visit and Smoking Deprivation Visit (Visits are randomly ordered, counterbalanced separated by  14 days) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Smoking, Hispanic, Latinx