OSV-IRM - Volunteer MRI Sequence Optimization

Study Overview
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Brief Summary
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Optimization of magnetic resonance imaging (MRI) protocols on healthy volunteers and voluntary patients. In MRI, a large number of technical parameters (sequence, parameters in sequence, antenna, reconstruction method, etc.) can be changed to optimize the diagnostic quality of the exam. Some optimizations can be performed on participants healthy volunteers, others need to be carried out on images pathological and acquired in voluntary patients.

Detailed Description
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An inclusion visit is planned to verify the criteria for selection, then an imaging visit to perform the MRI examination. The imaging visit can take place at the end of the inclusion visit and until the following 15 days. For healthy volunteers, the visits are organized according to their availability. For patients, on the other hand, participation in the research will depend on the programming of the MRI within the framework care. This is a single-center prospective study carried out at two sites in the Rennes University Hospital.

Official Title
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OSV-IRM - Volunteer MRI Sequence Optimization

Conditions
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MRI

Intervention / Treatment
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* Other: MRI


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Criteria common to all participants: Minor or major subject Affiliated, himself or through his parents if he is a minor, to a a social security scheme Having given their free, informed and written consent, and/or which the free, informed and written consent of the holder(s) parental authority has been obtained for minors Specific criteria for healthy volunteers: o No medical or surgical history related to the anatomical area(s) scanned Specific criteria for voluntary patients: o Indication for an MRI exam as part of its management Exclusion Criteria: - Contraindication to an MRI (pacemaker or pacemaker, neurostimulator, intra-orbital metal body, vascular clip ferromagnetic) Pregnancy Legal protection measure for adults in progress (safeguard of justice, guardianship, curatorship) or subject deprived of liberty

Ages Eligible for Study
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Minimum Age: 6 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Participants<br>Patients and Healthy volunteers included will have an MRI | Other: MRI<br>* MRI<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Quality of MRI signal | The quality of the images, maps or signals collected will be compared to standard acquisitions. This evaluation will be done by statistical comparison of visual qualitative criteria by expert radiologists or on quantitative criteria drawn from analyzes computing data obtained by processing experts images (signal-to-noise ratio, contrast-to-noise ratio, blur level, mutual information, co-location of regions highlighted by different techniques, etc.). | 15 days |