MAGNETIC RESONANCE IMAGING in Superficial Soft Tissue Masses

Study Overview
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Brief Summary
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This study responds to these raise up questions: Can we use Diffusion Weighted MR complemented with numerical ADC values & in association with routine MRI in the discrimination between different malignant and benign superficial soft tissue masses.

Detailed Description
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In the clinical practice, there is a large number & variety of superficial soft tissue masses. The differentiation of such masses represents a major obstacle for the surgeons. Benign &malignant neoplasms as well as non-neoplastic swellings may have similar clinical presentation. The differentiation between malignant & benign superficial soft tissue neoplasms is required for appropriate therapeutic planning and decisions. Masses can be characterized in terms of their size, number, component &vascularity using US and Doppler US. However, US is operator dependent & may display a number of artifacts that can result in misinterpretation. So MRI is superior in the assessment of such soft tissue masses due its brilliant soft tissue discrimination. Some features that will help distinguish malignant from benign lesions are evident on MRI examination such as signal characteristics,enhancement pattern,margin,lobulation,necrosis, haemorrhage,internal septation,peritumoral edema and extension through the deep fascia .However very forcful tumors may show benign behavior & appear similar to benign masses , Thus further histopathology is required for accurate diagnosis. Diffusion weighted MRI visualizes the random microscopic motion of molecules. Diffusion-weighted imaging (DWI) is the technique which allows measurement of the Brownian motion of water in the tissue microenvironment depending on the organization of the tissue, integrity of cell membranes, and tortuosity of extracellular space. Apparent Diffusion Coefficient (ADC) is a numerical parameter which is calculated from DWI. Previously, DWI technique was used with great success in the central nervous system (CNS), in the differentiation between benign and malignant tumors in addition to its great value in early diagnosis of recent strokes. Nowadays, DWI was used in the differentiation between malignant and benign soft tissue masses. Malignant tumors have abundant cellularity than benign tumors hence they have more restricted diffusion. The addition of quantitative ADC values plays a fundamental role in more accurate diagnosis of malignant superficial soft tissue neoplasms.

Official Title
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Role of MAGNETIC RESONANCE IMAGING in Characterization of Superficial Soft Tissue Masses

Conditions
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Soft Tissue Masses

Intervention / Treatment
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* Device: MAGNETIC RESONANCE IMAGING


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients with superficial soft tissue masses clinically patients underwent us detection of superficial soft tissue masses uncharactized superficial soft tissue mass by other modalities Exclusion Criteria: MRI claustrophobia recurrent cases patients under treatment
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Device: MAGNETIC RESONANCE IMAGING|s a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes of the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio waves to generate images of the organs in the body. MRI does not involve X-rays or the use of ionizing radiation, which distinguishes it from CT and PET scans. MRI is a medical application of nuclear magnetic resonance (NMR) which can also be used for imaging in other NMR applications, such as NMR spectroscopy.|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| benign and malignant masses | The discrimination between benign and malignant superficial soft tissue mass by Non invasive available technique | from october 2021 to october2022 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Type of malignant superficial soft tissue masses | Differentiation type of malignant superficial soft tissue masses | From October 2021 to October 2022 |