linjc16/ctgov huggingface dataset:
A Prospective Study of Axillary Hair Loss in Patients Treated With the miraDry System

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to evaluate hair reduction in the underarms in patients treated with the miraDry System.

Detailed Description
-----------------
This study is designed to quantify the amount of hair reduction in patients treated with the miraDry System in the axilla. Hair counts will be assessed before and after treatments including at follow up visits.

Official Title
-----------------
A Prospective Study of Axillary Hair Loss in Patients Treated With the miraDry System

Conditions
-----------------
Underarm Hair

Intervention / Treatment
-----------------
* Device: miraDry Treatment


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 18 years of age Visible underarm hair (prefer light colored hair; blonde, red, gray) Exclusion Criteria: Secondary Axillary Hyperhidrosis Prior surgery and/or Botox Injections in axillae Pacemaker or requires supplemental oxygen Pregnant

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Single Group miraDry Treatment<br>This is a single group study where each enrolled subject will receive active miraDry treatment in each axilla. | Device: miraDry Treatment<br>* Application of electromagnetic energy to heat the lower dermis.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Patients with successful hair reduction | Percentage of patients that show a >=30% reduction in underarm hair at the 3 month visit compared to baseline. | 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Patients with successful hair reduction | Percentage of patients that achieve a >=30% reduction in underarm hair at the 12 month visit compared to baseline | 12 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Underarm Odor, Underarm Hair, Underarm Hair Reduction, Axillary Hair, Axillary Hair Reduction, Axillary Odor
Influence of Head Positioning on the Movement of the Endotracheal Tube

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to evaluate and measure the movement of the endotracheal tube depending on the type and the amount of movement of the head of the patient intubated using a flexible fiberoptic.

Detailed Description
-----------------
We performed a maximal head-neck movement trial on 50 adult patients, American Society of Anaesthesiologists 1 or 2. Patients with body mass index N35 kg · m-2, height b150 cm, airway malformations, pulmonary diseases, difficulties in neck flexion or extension, previous ENT surgery or radiotherapy, gastroesophageal reflux, or dental instability were excluded from the study. We measured the change in distance between the ETT tip and the carina, using a fiberscope through the ETT.

Official Title
-----------------
Influence of Head Positioning on the Movement of the Endotracheal Tube

Conditions
-----------------
Other Conditions That May Be A Focus of Clinical Attention

Intervention / Treatment
-----------------
* Procedure: Head movement


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients older than 16 years ASA 1-2 Elective surgery Exclusion Criteria: Pathological changes of the trachea. Less than BMI 35 kg/m2. Patients with rheumatoid arthritis or other limitation to cervical mobility. Emergency surgery. Individuals measuring less than 150 cm.

Ages Eligible for Study
-----------------
Minimum Age: 16 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: head movement<br>head movement in extension, flexion, right and left rotation | Procedure: Head movement<br>* Head movement in extension, flexion, right and left rotation<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Displacement of the endotracheal tube. | Tube movement related to movement of the head | 24 hours | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Airway, Endotracheal intubation, selective intubation
Effect of Whey and Albumin Protein on Plasma Levels of Amino Acids

Study Overview
=================
Brief Summary
-----------------
The purpose of this study will allow us to examine how quickly and to what extent plasma amino acids levels rise after ingesting a single dose of either whey or albumin protein. The investigators anticipate that the amino acids from albumin concentrate protein will rise as quickly and to the same extent as amino acids from whey protein. These findings will help us to understand the biological availability of these proteins and efficacy of the supplement so that consumers may be presented with nutritional options.

Official Title
-----------------
Effect of Whey and Albumin Protein on Plasma Levels of Amino Acids

Conditions
-----------------
Healthy Men and Women

Intervention / Treatment
-----------------
* Dietary Supplement: Whey Milk Protein
* Dietary Supplement: Bovine Albumin Concentrate


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: normal Healthy volunteers free of serious illness/disease such as hypertension, kidney or liver disease Exclusion Criteria: taking dietary protein or amino acid supplements

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Whey Milk Protein<br> | Dietary Supplement: Whey Milk Protein<br>* 20 grams of Whey Milk Protein<br>|
| Experimental: Bovine Albumin Concentrate<br> | Dietary Supplement: Bovine Albumin Concentrate<br>* 20 grams of Bovine Albumin Concentrate<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Amino acid concentration |  | 210 minutes |
Effect of Materials for Subcuticular Suture (Quill vs. Monocryl) on Complications After Liver Resection

Study Overview
=================
Brief Summary
-----------------
This study investigates the effect of materials used in subcuticular suture on patients' outcomes after surgery. The prevention of surgical site wound infection is important to decrease the length of hospital stay and the post-operative risk of incisional hernia, especially in patients undergoing open hepatectomy (surgical removal of the liver). The purpose of this study is to compare the impact of the use of Quill versus Monocryl for subcuticular suture on patients' outcomes after surgery.

Detailed Description
-----------------
PRIMARY OBJECTIVE: I. To investigate the impact of materials for subcuticular suture (Quill versus [vs.] Monocryl) on complications after liver resection. OUTLINE: Patients' medical records are reviewed retrospectively.

Official Title
-----------------
Effect of Materials for Subcuticular Suture (Quill® vs. Monocryl®) on Complications After Liver Resection

Conditions
-----------------
Liver and Intrahepatic Bile Duct Neoplasm

Intervention / Treatment
-----------------
* Other: Electronic Health Record Review


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients >= 18 years of age undergoing liver resection at MD Anderson Cancer Center from June 1, 2020 through January 31, 2021 Exclusion Criteria: Patients who have a history of previous abdominal surgery will be excluded Pregnant women will not be included in this chart review

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Observational (medical record review)<br>Patients' medical records are reviewed retrospectively. | Other: Electronic Health Record Review<br>* Medical records are reviewed<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of complications after liver resection | The impact of materials for subcuticular suture (Quill versus Monocryl) on complications after liver resection will be evaluated. | 1 year |
Sensory Integration (Processing) Disorder Among Children With Behavioral Insomnia and Children With Feeding Disorder

Study Overview
=================
Brief Summary
-----------------
Behavioral insomnia of childhood is a prevalent condition, affecting 10-30% of children 6-36 months of age. If left untreated, bedtime problems and night wakings can negatively impact the daytime functioning and behavior of the child, as well as the entire family. Feeding difficulties are common in pediatric practice and encompass a spectrum ranging from children with physiological difficulties in ingesting food, through picky eaters to full fledged infantile feeding disorders. We have recently shown that feeding and eating difficulties are more prevalent among children with behavioral insomnia of childhood and that sleep problems are more frequent in children with feeding disorders. We hypotesize that SPD is a common etiology for both sleep and feeding disorders and that children with sleep or feeding disorder have increased rate of Sensory intergration disorder (SID) compared with healthy controls.

Official Title
-----------------
Sensory Integration (Processing) Disorder Among Children With Behavioral Insomnia and Children With Feeding Disorder

Conditions
-----------------
SID, Feeding Disorder, SPD

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: children 7-36 months of age with behavioral insomnia of childhood based on the International Classification of Sleep Disorders (ICSD) criteria . children 7-36 months of age with feeding disorders based on Chatoor criteria. children 7-36 months of age who attend well-care clinics in the metropolitan of Tel Aviv for routine periodic medical examination. Exclusion Criteria: Children with Chronic medical conditions. Congenital abnormalities. Significant developmental delay.

Ages Eligible for Study
-----------------
Minimum Age: 7 Months
Maximum Age: 36 Months

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Sleep Disorders<br>7-36 months old children with behavioral insomnia of childhood based on the International Classification of Sleep Disorders (ICSD) criteria will be recruited from the Pediatric Sleep Center at Dana Children's hospital | |
| Control<br>7-36 months old chidren of age who attend well-care clinics in the metropolitan of Tel Aviv for routine periodic medical examination. | |
| Feeding disorder<br>7-36 monthsold children with feeding disorders based on Chatoor criteria will be recruited from the clinic of feeding disorders at Dana Children's Hospital. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluation of sleep disorders using Brief Infant Sleep Questionnaire (BISQ) and feeding disorders using the Behavioral Pediatrics Feeding Assessment. |  | Imidietly after the questionnaire filled by the parent. |
Montelukast Post-marketing Comparative Study With Theophyline Added to Inhaled Corticosteroid (0476-396)

Study Overview
=================
Brief Summary
-----------------
A clinical study explores the safety and efficacy of montelukast and to compare the safety and efficacy of montelukast with those of theophylline in pediatric bronchial asthma patients when they are used in conjunction with inhaled steroids.

Official Title
-----------------
A Randomized Open-Label Comparative Study of Montelukast Versus Theophylline Added to Inhaled Corticosteroid in Pediatric Patients With Bronchial Asthma

Conditions
-----------------
Asthma

Intervention / Treatment
-----------------
* Drug: montelukast
* Drug: Theophylline


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Pediatric Bronchial Asthma Patients Aged 6 To 14 Years (At The Beginning Of The Treatment Period) The Severity Must Be Mild, Moderate Or Severe, Persistent Bronchial Asthma The Patient Must Have Symptoms That Can Be Used As Efficacy Variables (Such As Repeated Coughing And Mild Or Moderate Asthma Attacks) During The Observation Period, And Must Be Using Inhaled Steroids Exclusion Criteria: Patient Using Anti-Asthma Treatment Or Therapy Including corticosteroids Or Oral Anti-Allergic Drugs Patient With Complications That Will Impair The Judgment Of Efficacy Of This Drug Patient With Convulsive Disorders Such As Epilepsy Or Such A History Patient With Liver Disease, Renal Impairment, Heart Disease Or Such Other Complication

Ages Eligible for Study
-----------------
Minimum Age: 6 Years
Maximum Age: 14 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 1<br> | Drug: montelukast<br>* montelukast 5 mg QD 4-weeks.<br>* Other names: MK0476;|
| Active Comparator: 2<br> | Drug: Theophylline<br>* Theophylline 100 to 200 mg BID 4-weeks.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Improvement of AM PEF over first 2 Weeks |  | Over first 2 Weeks |
Standardized Long Term Follow-up of Patients After Endovascular Embolization of a Brain Aneurysm

Study Overview
=================
Brief Summary
-----------------
The time-frame and the follow-up elements after embolization of brain aneurysm are not standardized. Therefore, few reliable follow-up data are available for these patients. This study aims at collecting standardized long term data for these patients, in order to assess the occurence of aneurysm recanalization and particularly those requiring another intervention on the aneurysm.

Official Title
-----------------
Standardized Long Term Follow-up of Patients After Endovascular Embolization of a Brain

Conditions
-----------------
Aneurysm

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: curative embolization of a brain aneurysm age >18 years old Exclusion Criteria: none

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| long term evaluation of aneurysm occlusion | Roy classification | 5 years after embolization |
Thromboelastography, Platelet Function and Platelet Recovery in Haemato-oncologic Patients With Thrombocytopenia

Study Overview
=================
Brief Summary
-----------------
This is a prospective observational clinical study to characterise abnormalities of thromboelastography (TEG) parameters in patients with chemotherapy-induced thrombocytopenia. The investigators are also studying the relationship between Multiplate analysis and bleeding in these patients and the effect of platelet transfusions on thrombopoietin level and percent reticulated platelets. The investigators' hypothesis is that changes in TEG-parameters reflect the patients tendency to bleed.

Detailed Description
-----------------
Thrombocytopenic patients are followed with blood samples (thromboelastography, Multiplate, haematology) daily, Monday to Friday for up to 30 days. In addition bleeding evaluation is done daily ,using a standardized questionnaire. The questionnaire is filled out after interview of the patient, and som times next of kin and nurses. Nurse journals and medical journals are also used to fill in the questionnaires. For thromboelastography (TEG) we are looking at which parameters are abnormal, and if there is other factors than platelet count that influence the results. We will also compare TEG from days with and without bleeding, to see if they differ. For Multiplate we are doing a pilot study to see whether this analysis can be of any use at all in this group of patients. We are looking into which factors that influence the Multiplate result, and if we can see a difference in the results if the patient is bleeding. For reticulated platelets and thrombopoietin we are studying the levels related to platelet transfusions.

Official Title
-----------------
Monitoring of Thromboelastography, Platelet Function and Platelet Recovery in Haemato-oncologic Patients With Thrombocytopenia

Conditions
-----------------
Bone Marrow Diseases, Lymphoma

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients are eligible for this study if: They have a haemato-oncologic disease They have, or are expected to have, thrombocytopenia They are expected to need at least one platelet transfusion They are aged 18 years or over They consent to participate Exclusion Criteria: Patients are not eligible for this study if: They have a known congenital clotting disorder They need anticoagulants regularly in the study period They have immune thrombocytopenic purpura

Ages Eligible for Study
-----------------
Minimum Age: 16 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Hematooncology patients<br>No intervention | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| MA | To characterise changes in the TEG-parameter MA in patients with chemotherapy-induced thrombocytopenia | 1 year |
The Edmonton Symptom Assessment System (ESAS) as a Screening Tool for Depression in Cancer Pain Patients

Study Overview
=================
Brief Summary
-----------------
Compare Thai versions of the Edmonton Symptom Assessment System (ESAS) and the Hospiral Anxiety and Depression Scale (HADS) with Diagnostic and Statistical Manual (DSM-5), as a screening tool for depression in cancer pain patients

Official Title
-----------------
The Edmonton Symptom Assessment System (ESAS) as a Screening Tool for Depression in Cancer Pain Patients

Conditions
-----------------
Screening Tool for Depresion in Cancer Pain Patients

Intervention / Treatment
-----------------
* Other: Thai version of the Edmontom Symptom Assessment System (ESAS)


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Cancer patients who follow up as out patient at pain clinic, Siriraj hospital Age older than 18 years old Fluently read, write and speak in Thai language No cognitive impairment Exclusion Criteria: Unstable clinical presentation Severe pain or pain numerical rating scale more than 7 Severe associated symptoms such as nausea, vomiting The patient who do not know their diagnosis

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Cancer pain patients<br> | Other: Thai version of the Edmontom Symptom Assessment System (ESAS)<br>* Screening and diagnostic questionaire for depression<br>* Other names: Thai version of the Diagnostic and Statistical Manual (DSM-5);|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Reliability and validity of Thai version of ESAS | Cut-off point, sensitivity, specificity, positive predictive value and negative predictive value of Thai version of ESAS | 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Correlation of Thai version of ESAS, HADS and DSM-5 | Pearson correlation, Sperman rank correlation | 1 year | 
| Internal consistency of Thai version of ESAS and HADS | Cronbach's alpha | 1 year |