Postoperative Delirium in Cardiac Surgery ICU

Study Overview
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Brief Summary
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Postoperative Delirium (POD) is a common complication in patients after cardiac surgery, which is associated with short-term prognosis and long-term quality of life. Due to the lack of specific treatment, prevention is the most effective strategy to reduce delirium. Risk assessment greatly contributes to guide prevention by stratifying the risk of the POD. However, the high-quality risk assessment tools are still sparse, and the combination of risk assessment and stratified prevention has not been applied to the management of delirium after cardiac surgery. In the previous work, we found the predictive value of preoperative cardiac function on POD, and found a critical value. On the basis of previous research, this project will learn from previous studies on risk factors of POD, and deeply explore potential predictors. Furthermore, we will develop and validate POD risk prediction model, and then develop it into a visual evaluation system. In addition, based on the theory of risk management and risk assessment tools, using the concepts and methods of evidence-based medicine, the risk assessment system and stratified management program of POD will be formed and evaluated by expert discussion meetings. It is expected that the risk assessment system and stratified management program constructed by this project could simply and quickly screen high-risk patients and carry out timely intervention, so as to reduce the incidence of POD, improve patients' prognosis and the quality of life after cardiac surgery.

Official Title
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Study on Visual Assessment System and Stratified Management Program for Postoperative Delirium After Cardiac Surgery

Conditions
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Delirium

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Aged above 18 Patients after cardiac surgery Admitted to ICU after surgery Exclusion Criteria: Preoperative delirium or dementia patients Unable to fully participate in delirium testing, including blind, deaf, illiterate or inability to understand Chinese Undergoing surgery procedures do not require admission to SICU Transfer to ICU from wards after surgery

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| cardiac surgery patients in ICU<br> | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of postoperative delirium | Investigators defined patients have delirium if they had at least one positive screening during ICU stay. | up to 5 days postoperatively | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Severity of postoperative delirium | Assess by CAM-ICU-7 if CAM-ICU is positive. Categorized as no delirium: 0-2, mild to moderate delirium: 3-5, and severe delirium: 6-7 | up to 5 days postoperatively | 
| duration of postoperative delirium | Defined as time (in days) from the first positive CAM-ICU until the beginning of two consecutive days of negative CAM-ICU. | up to 5 days postoperatively | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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postoperative delirium, cardiac surgery, Intensive care unit, risk assessment