Neuromed- Integrated Health Life Platform and Biobank

Study Overview
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Brief Summary
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This project aims to create a digital platform for personal, clinical, diagnostic and environmental data collection, management and analysis of patients with cardiovascular and neurological disease or cancer admitted to the Neuromed Group clinics, associated with a biobanks of biological fluids and human tissues and a biotechnological platform for omics analysis, to encourage personalized, preventative and predictive care.

Detailed Description
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There is a need for a change of vision in health care that could become a key innovation point for digital medicine in the future, a sort of Copernican revolution: the starting point is no longer the disease, but the patient around whom pathologies and risk factors rotate, not as distinct and uniquely defined entities, but as communicating and interconnected possibilities that define their form only in relation to the individual, his genome, his personality, his habits of life and the environment in which he lives. From these interactions, a personalized, dynamic, integrated, and continuous diagnostic and therapeutic pathway is created that accompanies the person not only in the stage of the disease but also in the previous and subsequent phases, becoming a way of life oriented towards the health of the person rather than a way to cure a disease. An Integrated Health Life Platform enables you to develop an interactive healthcare health model among all actors who manage the health of the person, healthcare professionals in the area, and hospitals, caregivers, and community through the integration of remote monitoring of data with A virtual community. The platform is thought not as a pure aggregation of data, but as a digital hub centered on the patient, with his (clinical and personal) data, but also the environment in which he lives, his behaviors, accessibility to services and The relationships that come to them and from them. The platform aims to effectively integrate self management, personalization of the path, and co-production of health, demonstrating that these three key dimensions of care are mutually reinforcing.

Official Title
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Neuromed- Integrated Health Life Platform and Biobank

Conditions
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Cardiovascular Diseases, Neuro-Degenerative Disease, Cancer, Pregnancy

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Men and women Older than 18 years Cardiovascular disease neurodegenerative disease Cancer Pregnancy Exclusion Criteria: Inability to understand and to want Refusal to sign the informed consent

Ages Eligible for Study
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Minimum Age: 19 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Biological sample bank | A repository of biological samples, Neurobiobank, from patients who will join the project, will be organised at the biotechnology park of Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Neuromed of Pozzilli under the responsibility of the experienced staff at the Department of Epidemiology and Prevention. | baseline | 
| Integrated health-life big data platform | Analytical tools will be developped for integrating structured and unstructured patients data sets and derive actionable information from their observed interrelationships. | baseline | 
| omics analysis | Measure of genomic, epigenetic and proteomic fingerprint of recruited patients | baseline | 
| Four P (4P) medicine | Identification of patterns within the health data that correlate with disease or wellness and create personalised pathway of prevention and care. | Baseline | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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biobank, chronic disease, omics, big data, 4 P medicine