Movement Pattern in Patients With Hip Dysplasia

Study Overview
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Brief Summary
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The purpose of this study is to examine the movement pattern in patients with hip dysplasia preoperative, six and 12 month after minimally invasive approach for Periacetabular osteotomy (PAO). Secondary to examine the movement pattern in patients compared to healthy controls and historical data.

Detailed Description
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Congenital hip dysplasia is a disease characterised by pathological changes in the hip joint. Hip dysplasia is a normal disease with a prevalence of 4.3% in men and 3.6 in woman. Untreated hip dysplasia is a known cause of developing osteoarthritis early in life and symptoms as pain, hip instability together with a changed gait pattern are normal. Symptomatic hip dysplasia is seen in patients between 15 and 55 years and can be unilateral as well as bilateral. Causes of hip dysplasia are described as genetic, mechanic or hormonal. Today patients with hip dysplasia are offered a hip conserving surgery before the osteoarthritis has developed. In 2003 a minimally invasive approach for periacetabular osteotomy (PAO) was introduced at Aarhus University Hospital. An advantage of minimally invasive approach compared to the classical Bernese periacetabular osteotomy is minimal impact of the soft tissues in the hip region. Hip pain and activity limitations highly affect quality of life and physical function. The gait distance is reduced and patients have to compensate to relieve the pressure on the hip joint. Knowledge about the dynamics of the gait and running pattern in patients with dysplasia is important to understand the consequences of the dysplastic hip joint. Furthermore knowledge about gait compensations is relevant for the clinicians in the management and treatment of patients with hip dysplasia. Today, gait and running compensation is unknown after minimally invasive approach The purpose of this study is, therefore, to examine the movement pattern in patients with hip dysplasia preoperative, six and 12 month after minimally invasive approach for Peri-acetabular osteotomy (PAO). Secondary to examine the movement pattern in patients compared to healthy controls and historical data.

Official Title
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Movement Pattern in Patients With Hip Dysplasia Operated With Minimally Invasive Approach in Peri-acetabular Osteotomy (PAO)

Conditions
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Hip Dysplasia

Intervention / Treatment
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* Procedure: Minimally invasive approach for Periacetabular osteotomy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients diagnosed with hip dysplasia Patients in the age of 18-60 years Patients, who can speak, understand and read Danish Exclusion Criteria: Persons with hip dysplasia secondary to other hip conditions such as Calvé Perthes and epiphysiolysis. Persons who have had alloplastic surgery in the hip, knee or ankle. Persons with diseases that affect the gait pattern. Persons with serious hip, knee, ankle or back pain.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| hip dysplasia<br>Patients with hip dysplasia | Procedure: Minimally invasive approach for Periacetabular osteotomy<br>* A peri-acetabular osteotomy is a surgery performed to correct the dysplastic acetabulum and reduce joint contact pressures and early osteoarthritis.<br>* Other names: PAO (periacetabular osteotomy);|
| Healthy people<br>Enrolled from the patients acquaintance circle | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Hip flexion's muscle moment in stance evaluated in gait, run and jump test | Examined using 3D Movement Capture System | Preoperative (baseline), 6 and 12 month postoperative | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Hip extension angle evaluated in gait, run and jump test | Examined using 3D Movement Capture Systen | Preoperative (baseline), 6 and 12 month postoperative | 
| On-set of the hip muscles evaluated in gait, run and jump test | Examined using skin electromyography (EMG) | Preoperative (baseline), 6 and 12 month postoperative | 
| Function, sports and recreational activities | Evaluated with Hip Dysfunction and Osteoarthritis Outcome Score (HOOS) and The Copenhagen Hip and Groin Outcome Score (HAGOS) | Preoperative (baseline), 6 and 12 month postoperative | 
| Quality of life | Evaluated with Hip Dysfunction and Osteoarthritis Outcome Score (HOOS) and The Copenhagen Hip and Groin Outcome Score (HAGOS) | preoperative (baseline), 6 and 12 month postoperative | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Movement capture system, Movement analysis, Hip dysplasia, Hip pain, Quality of life, Physical function