Development and Validation of Models to Predict Postoperative Complications for Patients With Cardiac Surgery

Study Overview
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Brief Summary
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Patients undergoing cardiac surgery is routinely performed in clinical scenarios, highly postoperative morbidities and long-term mortality should be modified. A simple risk prediction model incorporating risk factors can help guide clinical decision making, patient counseling and treatment planning.

Detailed Description
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Patients undergoing cardiac surgery is routinely performed in clinical scenarios, highly postoperative morbidities and long-term mortality should be modified.A nomogram is a pictorial representation of a scoring model that possesses a simple user interface and shows favorable predictive performance. By integrating a patient's diverse determinant variables, a nomogram can provide a personalized probability for quantitative predictions of the incidence of an outcome of interest.Therefore, we conducted a retrospective study to assess the incidence, risk factors and outcomes associated with major complications patients undergoing cardiac surgery.

Official Title
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Development and Validation of Models to Predict Postoperative Complications for Patients With Cardiac Surgery

Conditions
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Surgery--Complications

Intervention / Treatment
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* Other: Patients diagnosed with postoperative complications
* Other: Patients without postoperative complications


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age more than 18 years Undergoing Cardiovascular surgery Exclusion Criteria: Missing primary outcomes or variables

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients with postoperative complications<br>Patients with postoperative complications | Other: Patients diagnosed with postoperative complications<br>* Patients diagnosed with postoperative complications (Acute kidney injury, Chronic Kidney disease, Infection, Delirium, MACCE, Myocardial infarction, Postoperative pulmonary complications, major bleeding, ECMO, IABP....)<br>|
| Patients without postoperative complications<br>Patients without postoperative complications | Other: Patients without postoperative complications<br>* Patients without postoperative complications<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| postoperative complications: acute kidney injury | Diagnosed acute kidney injury (KDIGO) | 30 dyas | 
| postoperative complications: Chronic Kidney disease | Diagnosed Chronic Kidney disease | 30 days, as follow up | 
| postoperative complications: Infection | Diagnosed infection | 30 days | 
| postoperative complications: delirium | Diagnosed delirium (CAM,CAM-ICU) | 30 days | 
| postoperative complications: MACCE | Diagnosed MACCE | 30 days, as follow up | 
| postoperative complications: major bleeding | Diagnosed major bleeding | 30 days | 
| postoperative complications: postoperative pulmonary complications | Diagnosed postoperative pulmonary complications | 30 days | 
| postoperative complications: ECMO | patients with ECMO | 30 days | 
| postoperative complications: IABP | patients with IABP | 30 days | 
| Ventilation time | Number of hours the patient with mechanical ventilation | Through study completion, an average of 7 days | 
| Length of ICU stay | Number of days the patient stays in the intensive care unit | Through study completion, an average of 30 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Total hospital costs | Total cost of the stay in the hospitalization (USD) | Through study completion, an average of 30 days | 
| ICU costs | Total cost of the stay in the intensive care unit (USD) | Through study completion, an average of 30 days | 
| Length of hospital stay | Number of days the patient stays in the hospital | Through study completion, an average of 30 days | 
| Length of postoperative hospital stay | Number of days the patient stays in the hospital after surgery | Through study completion, an average of 30 days |