Use of Various Laser Systems in Peri-implatit

Study Overview
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Brief Summary
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Objectives: In recent years, a new field of work has been created with the use of laser beam to provide titanium surface decontamination. The aim of this study was to evaluate the effect of various laser systems in smokers and non-smokers with peri-implantitis. Materials and Methods: According to the study protocol, patients, who were diagnosed with peri-implantitis based on the clinical and radiographic evaluations, were divided into six groups: Group 1: smokers undergoing diode laser application; Group 2: smokers undergoing Erbium, chromium: yttrium, scandium, gallium, garnet (Er, Cr:YSGG) laser application; Group 3: smokers undergoing Erbium:yttrium-aluminum-garnet (Er:YAG) laser application; Group 4: non-smokers undergoing diode laser application; Group 5: non-smokers undergoing Er, Cr:YSGG laser application; and Group 6: non-smokers undergoing Er:YAG laser application. Peri-implant sulcus depth (SD), clinical attachment level (CAL), suppuration, modified plaque index (mPI), gingival index (GI), and modified sulcus bleeding index (mSBI) were recorded and peri-implant sulcus fluid (PISF) was collected to evaluate osteocalcin.

Official Title
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Effect of Various Laser Systems in Smokers and Nonsmokers With Peri-implantitis: A Randomized, Prospective, Single-Blind Clinical Trial

Conditions
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Peri-Implantitis

Intervention / Treatment
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* Device: Lasers


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Presence of pocket in probing depth of ≥4 mm in at least one implant No mobility in implant Implants with bridge foot and opposite occlusion Having no systemic disease that may affect the outcome of treatment No systemic use of antibiotics for the last six months Not receiving peri-implantitis treatment for the last three months Individuals at the 30-60 years of age. Exclusion Criteria: Individuals who did not agree to participate in the study Individuals receiving radiation therapy Individuals using alcohol Presence of pregnancy and lactation period Individuals with parafunctional habits such as clenching or bruxism.

Ages Eligible for Study
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Minimum Age: 30 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Diode laser<br> | Device: Lasers<br>* The laser tip was applied as vertical and horizontal scan along the subgingival implant . The procedure was carried out on day zero, seven and 14.<br>|
| Experimental: Er,Cr:YSGG laser<br> | Device: Lasers<br>* The laser tip was applied as vertical and horizontal scan along the subgingival implant . The procedure was carried out on day zero, seven and 14.<br>|
| Experimental: Er:YAG LAser<br> | Device: Lasers<br>* The laser tip was applied as vertical and horizontal scan along the subgingival implant . The procedure was carried out on day zero, seven and 14.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Sulcus depth |  | basaline - six month |