The Effect of a Citrus Extract on Exercise Performance in Moderately Trained Athletes

Study Overview
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Brief Summary
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In this study, the effect of citrus extract on exercise performance will be investigated. The study consists of three groups: one group will receive a high dose citrus extract, one group will receive a low dose citrus extract and the last group will receive a placebo. After four and eight weeks the effects on performance are measured through a Wingate cycling test. It is expected that exercise performance will increase in the citrus extract groups, compared to the placebo group.

Official Title
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Establishing the Effect of Long-term Citrus Extract Supplementation on Exercise-specific Performance in Moderately Trained Athletes

Conditions
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Exercise Performance

Intervention / Treatment
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* Dietary Supplement: citrus extract
* Other: placebo


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: healthy idividuals Participants are amateur or (semi-) professional athletes in resistance or interval sports (engage in >4 hours of intense physical activity per week). Exclusion Criteria: Use of creatine supplements and/or anabolic steroids. Allergy to test product/placebo Allergy to citrus fruits BMI lower than 18 or higher than 30 Recent muscle injury in less than one month before the start of the study. Cardiovascular complications Use of medication that may interfere with the study results Administration of investigational drugs or participation in any scientific intervention study which may interfere with this study (to be decided by the principle investigator), in the 180 days prior to the study. Abuse of products; alcohol (> 20 alcoholic units per week) and drugs.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 35 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: high dose citrus extract<br>this group will receive a high dose (500mg/day) of the citrus extract for 8 weeks | Dietary Supplement: citrus extract<br>* Participants will receive either a low or high dose citrus extract<br>|
| Experimental: low dose citrus extract<br>this group will receive a low dose (400mg/day) of the citrus extract for 8 weeks | Dietary Supplement: citrus extract<br>* Participants will receive either a low or high dose citrus extract<br>|
| Placebo Comparator: placebo<br>this group will receive a placebo (500mg maltodextrin per day) for 8 weeks | Other: placebo<br>* participants will receive 500mg of maltodextrin<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| peak force output Wingate | Peak force output in Watts during a high intensity repeated sprint cycling exercise | 8 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| jumping height | jumping height in cm measured during a vertical jump exercise | 8 weeks | 
| peak force output Handgrip | Peak force output in Watts during a handgrip strength test | 8 weeks | 
| force output Jump | force output in W measured during a vertical jump exercise | 8 weeks | 
| anaerobic capacity | total amount of power (W) generated in the first 30 seconds of the the triple Wingate cycle test | 8 weeks | 
| running time | running time in minutes and seconds measured over 1600m | 8 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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performance, polyphenols, nutrition, sports