Taiwan Cohort - Chronic ThromboEmbolic Pulmonary Hypertension Registry

Study Overview
=================
Brief Summary
-----------------
The diagnosis of chronic thromboembolic pulmonary hypertension (CTEPH) is difficult for numerous reasons and is related with a poor prognosis. In Taiwan, the incidence of CTEPH and its clinical features are unknown. This study aims at evaluating the prevalence, clinical characteristics, and management of CTEPH in a Taiwanese cohort. Primary objective: - To investigate the geodemographics of CTEPH in Taiwan Secondary objectives: To characterize the demographics and clinical presentation of patients with CTEPH To describe the real-world management and treatment outcome of patients with CTEPH To identify the risk factors of CTEPH To assess the relationship between risk factors/patients' characteristics and clinical outcomes for CTEPH To evaluate the prognosis of CTEPH in Taiwan using survival assessment

Official Title
-----------------
Taiwan Cohort - Chronic ThromboEmbolic Pulmonary Hypertension Registry

Conditions
-----------------
The Geodemographics of CTEPH in Taiwan

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Right heart catheterization (RHC) results that are in line with both of the following haemodynamic levels: Mean pulmonary arterial pressure (mPAP) ≥ 25 mmHg at rest AND Pulmonary arterial wedge pressure (PAWP) ≤ 15 mmHg Confirmation of CTEPH diagnosis by one of the following as recommended by standard guidelines: At least 1 (segmental) perfusion defect(s) in ventilation-perfusion (V/Q) / perfusion scan OR Pulmonary artery obstruction seen by multidetector computed tomography (MDCT) angiography or conventional pulmonary cineangiography. Presence of pulmonary hypertension or evidence of pulmonary thromboembolism after at least 3 months of anticoagulation treatment. Exclusion Criteria: not written informed consent not meet inclusion criteria

Ages Eligible for Study
-----------------
Minimum Age: 20 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To investigate the geodemographics of CTEPH in Taiwan | variables of interest also include (1) patients characteristics, such as demographics and medical history; (2) clinical features and diagnosis records, such as risk factors, comorbidities, CTEPH diagnosis data, concomitant conditions; (3) management of CTEPH, including surgery and medication; and (4) clinical outcome including clinical assessment results, survival status, and clinical worsening related to CTEPH. | recruiting period two years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To characterize the demographics and clinical presentation of patients with CTEPH - To describe the real-world management and treatment outcome of patients with CTEPH - To identify the risk factors of CTEPH - To assess the relationship between risk f | detail information descriptive in protocol | recruiting period two years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Chronic ThromboEmbolic Pulmonary Hypertension