Assesment of New Devices for the Diagnostic Evaluation of Diaphragmatic Dysfunction

Study Overview
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Brief Summary
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this study aim to evaluate wether new, non-invasive and non-contact devices such as Structured Light Plethysmography (SLP) and Sonar would be able to accurately detect and quantify diaphragm dysfunction (mono-or-bilateral) by assessing the asymmetric chest wall motion generated during spontaneous breathing as compared with a classic, standard and invasive technique.

Detailed Description
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The measurements of chest and abdominal wall movements during quiet tidal breathing will be performed simultaneously using SLP and Sonar devices. Subjects will be asked to sit down on a chair with their neck in a neutral position and their back as straight as possible. The SLP and the Sonar will be lined up to project the grid of light and the ultrasonic wave sonar over the participant's chest and abdomen. Data will be collected during 5 minutes of tidal breathing. The same procedure will be repeated while having the patient lying down in supine position on the same chair for 5 additional minutes. During both sessions (sitting and supine), patients will be asked to perform a gentle inspiratory capacity (IC) maneuver to better appreciate the thoraco-abdominal asymmetry and distortion.

Official Title
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Assesment of New Devices for the Diagnostic Evaluation of Diaphragmatic Dysfunction

Conditions
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Diaphragmatic Paralysis, Healthy Volunteers

Intervention / Treatment
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* Device: Sonar
* Device: Structured light plethysmography (SLP)


Participation Criteria
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Eligibility Criteria
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FOR HEALTHY VOLUNTEERS Inclusion Criteria: no respiratory disease no neurologic disease no thoracic deformation Exclusion criteria respiratory disease neurologic disease thoracic deformation FOR PATIENTS Inclusion Criteria: patients with a suspicion of diaphragmatic dysfunction Exclusion Criteria: pregnant women contraindications to standard procedure requiring transdiaphragmatic measurement

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients<br>Patients with a suspicion of diaphragmatic dysfunction | Device: Sonar<br>* Measurements of chest wall and abdominal wall movement will be performed while subjects are breathing quietly<br>Device: Structured light plethysmography (SLP)<br>* Measurements of chest wall and abdominal wall movement will be performed while subjects are breathing quietly<br>|
| Healthy volunteers<br>Subjects without any medical condition | Device: Sonar<br>* Measurements of chest wall and abdominal wall movement will be performed while subjects are breathing quietly<br>Device: Structured light plethysmography (SLP)<br>* Measurements of chest wall and abdominal wall movement will be performed while subjects are breathing quietly<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| amplitude of displacement of thoraco-abdominal compartments | asymmetry of displacement of thoraco-abdominal compartments during tidal breathing and respiratory manoeuvres | 10 minutes | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| displacement speed of thoraco-abdominal compartments | asynchrony of displacement of thoraco-abdominal compartments during tidal breathing and respiratory manoeuvres measurement | 10 minutes | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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structured light plethysmography, sonar, transdiaphragmatic pressure