Comparison of Sun Protection Factor 30 Persistence Between Inorganic and Organic Sunscreen in Swimmer

Study Overview
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Brief Summary
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Prolonged sunlight exposure in swimming athletes can cause various changes in the skin; among them is sunburn. The use of sunscreen can reduce sunburn effectively. However, various types of physical activity that can trigger sweating, friction, washing with water, or sun exposure after sunscreen use can interfere with its effectiveness in the form of a decreased SPF level. The purpose of this study is to determine and compare the persistence of organic and inorganic sun protection factor 30 (SPF 30) sunscreens after 1.5 hours of swimming.

Official Title
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Comparison of Sun Protection Factor 30 Persistence Between Inorganic and Organic Sunscreen in Swimmer

Conditions
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Sunscreen Persistence

Intervention / Treatment
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* Other: Inorganic sunscreen
* Other: Organic sunscreen


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Female or male swimming athletes aged 18-40 years. Practice swimming at least 3 times a week with a duration of 1.5-2 hours per practice in the morning or afternoon. Willing to be the subject of research by signing the consent. Do not have skin diseases. Do not have a history of allergies to sunscreens. Exclusion Criteria: Existence of skin lesion in the test area. In the treatment of phototherapy. Using drugs with photosensitivity side effects. History of skin malignancy, history of photosensitivity reactions or history of disease affected by UV rays. Exposure to direct sunlight to the test area 24 hours before the study and during the study period. Absence of erythema response 24 hours after the radiation test. Erythema occurs in the entire test area box 24 hours after the radiation test.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 40 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Inorganic sunscreen<br> | Other: Organic sunscreen<br>* Organic sunscreen will be applied evenly to 2 areas on the back of the subject with a 1 cc syringe and gloved finger in an amount of 2 mg / cm2. In the first session, one area will be irradiated 20 minutes after sunscreen application. In the second session, the other area will be irradiated after the subject has swam for 1.5 hours.<br>|
| Experimental: Organic sunscreen<br> | Other: Inorganic sunscreen<br>* Inorganic sunscreen will be applied evenly to 2 areas on the back of the subject with a 1 cc syringe and gloved finger in an amount of 2 mg / cm2. In the first session, one area will be irradiated 20 minutes after sunscreen application. In the second session, the other area will be irradiated after the subject has swam for 1.5 hours.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| SPF change after swimming for 1.5 hours | SPF of inorganic and organic sunscreen were calculated before and after swimming. The difference between SPF before and after swimming will be calculated and compared between the organic and inorganic group. SPF were calculated using minimal erythemal dose (MED) test. The test itself will be conducted in 2 days. Irradiation will be conducted on the first day and minimal erythemal dose result will be collected 24 hours after the irradiation. | 24 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Inorganic sunscreen SPF | SPF resulted from in vivo method, conducted before swimming. SPF were calculated using MED test. The test itself will be conducted in 2 days. Irradiation will be conducted on the first day and MED result will be collected 24 hours after the irradiation. | 24 hours | 
| Organic sunscreen SPF | SPF resulted from in vivo method, conducted before swimming. SPF were calculated using minimal erythemal dose test. The test itself will be conducted in 2 days. Irradiation will be conducted on the first day and minimal erythemal dose result will be collected 24 hours after the irradiation. | 24 hours |