Development of MRI Protocols and Associated Explorations (EEG, NIRS) in Healthy Volunteers

Study Overview
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Brief Summary
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The main objective of the studies that will be carried out on volunteer patients who have given their consent will be the development and optimization of the sequence parameters or the design of the stimulation paradigms in order to optimize the quality and Relevance of the images realized taking into account anatomical, functional or metabolic parameters. These adjustments will be carried out without interfering with the management of voluntary patients

Detailed Description
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The pathologies that interest us in these refinements concern mainly the chronic (or sequellar) brain disorders which can be degenerative, developmental or vascular. The patients who will be recruited will be known patients of our Service (University Clinic of Neuroradiology and MRI) that we follow during checks. The type of examination that will be applied to them, between MRI, EEG and NIRS, will be specified in the consent form. These examinations will not be invoiced either to the patient or to the social security, and the related costs will be borne by our Federative Research Structure or sometimes, when these explorations are upstream of a defined research protocol and funded, They will be financed under this protocol.

Official Title
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Development of MRI Protocols and Associated Explorations (EEG, NIRS) in Healthy Volunteers

Conditions
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Magnetic Resonance Imaging

Intervention / Treatment
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* Radiation: MRI
* Device: EEG
* Device: NIRS


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: major socially insured persons given their consent. absence of contraindication to the MRI examination Exclusion Criteria: Subjects under the age of 18 pregnant women all other persons referred to in articles L1121-5 to L1121-8 of the CSP

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Interventional Model Description: Methodological development of new MRI approaches
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Development of MRI protocols<br>MRI exam to grade differents interventions for future research | Radiation: MRI<br> <br> |
| Experimental: Development of EEG protocols<br>EEF exam to grade differents interventions for future research | Device: EEG<br> <br> |
| Experimental: Development of NIRS protocols<br>NIRS exam to grade differents interventions for future research | Device: NIRS<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Spatial resolution of new MRI imaging sequences MRI scanning. |  | Two hours |