Multicenter Study on Organ Acquisition Costs in the Post Re-Allocation Era: Liver Transplantation

Study Overview
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Brief Summary
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Organ procurement organizations (OPO) have increased organ recovery efficiency and yield and have also reduced organ acquisition charges. The new liver allocation policy came into effect in February 2020 and aims to increase access to organs for waitlist candidates with the greatest severity of illness. The urgent change was driven by the perception that patients were dying because of arbitrary boundaries and inequitable access. Critics of the new policy have highlighted the potential cost implications particularly at an OPO level. A study of five OPOs throughout the United States highlighted an increase in costs ranging from 43% - 206% despite the same volume of livers transplanted. The main reason for the cost appears to lie in organ handling and transport. This mirrors the findings of Puri and colleagues who acknowledged changes to lung transplantation at Barnes Jewish Hospital in the pre- and post-policy eras and reported a substantial decline in local donors. The new lung system has also resulted in a higher organ discard rate and ultimately higher costs. Such data has generated meaningful discussions regarding optimizing organ allocation polices, however, data from individual transplant centers is lacking in the literature. Changes at a transplant center level relating to recipient costs are likely impacted by the new policy, which could be related to patient travel, accommodation, work up etc.

Official Title
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Multicenter Study on Organ Acquisition Costs in the Post Re-Allocation Era: Liver Transplantation

Conditions
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Liver Transplant

Intervention / Treatment
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* Procedure: Liver Transplantation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 18 years or older Underwent liver transplantation at MDMC between February 4th 2019 - February 4th 2020 and February 5th 2020 - February 5th 2021 Exclusion Criteria: Below 18 years of age Did not undergo liver transplantation

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Liver Transplantation patients<br> | Procedure: Liver Transplantation<br>* Patients who underwent liver transplantation at Methodist Dallas Medical Center<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Liver transplant volume |  | 02/04/2019 - 02/05/2021 | 
| Cost | Costs related to: Transplant volume and organ recovery information Transportation costs, distance traveled, travel time Personnel costs Hospital charges/costs | 02/04/2019 - 02/05/2021 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Organ Procurement and Transplant Network (OPTN), Liver Allocation Policy