Effect of the High Impact Exercise on Bone Density in Prepuberal Girls

Study Overview
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Brief Summary
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Osteoporosis has become a worldwide concern an a matter of public health as osteoporosis is a major contributing factor associated with insufficiency fracture of the spine, wrist and proximal femur, and as a result, can diminish quality of life as well as increase direct and indirect healthcare costs. The pathophysiology of osteoporosis is based on two main factors; low bone mass and age associated architectural changes within the bone, high impact exercise in childhood can improve the peak bone mass and bone architecture. The evidence suggests that bone adaptation to increased load is optimal in early puberty (Tanner stages I and II) since around 30% of total body adult bone mass is accrued during this period. However, the optimal exercise program for increasing peak bone mineral content is still unclear. Therefore, the aim of this study is to assess if 15 minutes of high-impact exercise three times per week improve areal bone mineral density assessed by DXA of pre pubertal girls after a ten-month regimen compared to low-impact exercise. This information could highly impact the development of public health policies directed to pre pubertal girls.

Official Title
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Effect of the High Impact Exercise on Bone Density in Prepuberal Girls in 12 Private Schools in Bogota - Colombia During 2016 - 2017. Open Label Randomized Controlled Trial

Conditions
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Bone Loss, Age-Related,

Intervention / Treatment
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* Other: High Impact Exercise
* Other: Low Impact Exercise


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Girls between ages 8 to 10 Tanner I Exclusion Criteria: Precocious menarche (within the selected timeframe) Chronic disorders or medications known to affect bone metabolism or musculoskeletal function. Body Mass Index 30 or higher Regular vigorous physical activity (training more than 8 hours per week)

Ages Eligible for Study
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Minimum Age: 8 Years
Maximum Age: 10 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: High Impact Exercise<br>weight bearing exercises, jumps, plyometric exercises | Other: High Impact Exercise<br>* In these workouts, both feet leave the ground at the same time.<br>|
| Sham Comparator: Low Impact Exercise<br>Walking, Strength training, Cycling, Yoga. | Other: Low Impact Exercise<br>* A workout is low-impact if at least one of your feet remains in contact with the ground at all times.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| bone mineral density (BMD) are presented for the total Body total bone mineral density | whole body whole Amount of mineral matter per square centimeter of bones. | 36 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Bone Mineral Density, Isometric Exercise, Bone Growth