EFFECTIVENESS OF GRADED MOTOR IMAGERY TO PREVENT CRPS IN PATIENTS WITH DISTAL RADIUS FRACTURE AFTER SURGERY

Study Overview
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Brief Summary
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The study would like show that patients who follow a protocol with GMI are less probability to develop CRPS

Detailed Description
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Distal radius fractures (DRF) has a high frequency in adults. Studies show that the upper limb is frequently affected by CRPS, especially if is preceded by a fracture. Recent studies suggest that changes in cortical structures can contribute to the onset of CRPS. GMI is a approved and efficacy method in CRPS rehabilitation, because it trains modified cortical areas throught 3 stadies: left-right discrimination, visual motor imagery and mirror therapy. Literature shows that there are any studies about GMI efficacy on prevention CRPS in DRF after surgery. This study would like to demostrate that, appling GMI in the early stages of rehabilitation plus standard rehabilitation protocol of DRF after surgery, CRPS cases are reducted.

Official Title
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EFFECTIVENESS OF GRADED MOTOR IMAGERY TO PREVENT CRPS IN PATIENTS WITH DISTAL RADIUS FRACTURE AFTER SURGERY: A RANDOMIZED CONTROLLED TRIAL

Conditions
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Wrist Fracture, CRPS (Complex Regional Pain Syndromes), Distal Radius Fracture, Surgery

Intervention / Treatment
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* Other: GMI protocol
* Other: Standard Rehabilitation Protocol


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients with distal radius fracture after surgery 18 to 75 years old Male and female Exclusion Criteria: uncompliants patients patients with neurological disorders or cognitive impairment patients with TFCC injury or both ulna and radius fractures patients with visually impairment patients who don't speak or understand oral and written italian language

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: A group<br>In this group patients follow standard treatment after radius fracture plus GMI procol | Other: GMI protocol<br>* This group follow GMI program split in 3 step: left/right descrimination visual motor imagery mirror therapy Patients perform this exercises 3 times every day and they have checks in therapy al least twice a week.<br>Other: Standard Rehabilitation Protocol<br>* This group follow standard rehabilitation protocol, with active and passive motion of upper limb structure, including hand, wrist, elbow, shoulder. Patients perform this exercises 3 times every day and they have checks in therapy al least twice a week.<br>|
| Active Comparator: B group<br>In this group patients follow standard treatment after radius fracture | Other: Standard Rehabilitation Protocol<br>* This group follow standard rehabilitation protocol, with active and passive motion of upper limb structure, including hand, wrist, elbow, shoulder. Patients perform this exercises 3 times every day and they have checks in therapy al least twice a week.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Range Of Motion | Change in active and passive range of motion about hand and wrist | Baseline and 8 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Patient-rated wrist/hand evaluation (prwhe) | Decrease in difficulty of doing activities of daily living and decrease pain | Baseline and 8 weeks | 
| Jamar hand dynamometer | Improve strength | Baseline and 8 weeks | 
| McGill pain questionnaire | Decrease pain | Baseline and 8 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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GMI, CRPS, Distal radius fracture