Effect of Modified Stylet Angulation on the Intubation With GlideScope®

Study Overview
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Brief Summary
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The GlideScope® videolaryngoscope usually visualize glottis better than the conventional laryngoscope. Under the visualization of glottis by GlideScope®, the insertion of endotracheal tube, however, is challenging. The goal of this study was to determine which of two stylet (70° vs 90°) was better, as determined by time to intubation.

Official Title
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Stylet Angulation of Seventy Degrees Reduced Time to Intubation With the GlideScope®: A Prospective Randomized Trial

Conditions
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Cholecystitis, Stomach Cancer

Intervention / Treatment
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* Procedure: Glidescope guided intubation
* Device: GlideScope®


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients requiring endotracheal intubation for general anesthesia Exclusion Criteria: Difficult airway Rapid sequence induction Recent sore throat Fragile teeth Contraindication for videolaryngoscope Head and neck surgery

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: 90 degree<br>The ETT with the 90° angle stylet was bent at a point 8 cm from its distal end. | Procedure: Glidescope guided intubation<br> <br> Device: GlideScope®<br> <br> |
| Experimental: 70 degree<br>The ETT was bent by 70° at a point 6 cm from its distal end and the proximal portion of the ETT was formed as the shape of the GL blade until the point of the handle. | Procedure: Glidescope guided intubation<br> <br> Device: GlideScope®<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Time to Intubation | Time from the insertion of the Glidescope blade to the measurement of end tidal CO2 (>30 mmHg) | Intraoperative intubation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Success Rate of Intubation | The number of patients in which the intubation was successful at the first time. | Intraoperative intubation | 
| Difficulty of Intubation Measured Using Visual Analogue Scale | Difficulty of intubation will be measured using visual analogue scale (0:easiest, 100:most difficult). | Intraoperative intubation | 
| Number of Participants for Whom External Laryngeal Manipulation Was Necessary | External laryngeal manipulation is defined as the compression of neck for the facilitation of laryngeal view. Number of participants for whom external laryngeal manipulation was necessary will be measured. | Intraoperative intubation | 
| Cormack-Lehan Grade | The grade of Cormack-Lehan was assessed as I/II/III/IV (I: Full view of glottis, II: Partial view of glottis, III: Only epiglottis seen, none of glottis seen, IV: Neither glottis nor epiglottis seen). Grade I was considered better outcomes. | Intraoperative intubation | 
| Mallampati Grade | The Mallapati grade was assessed as I/II/III/IV (I: Soft palate, uvula, fauces, pillars visible, II: Soft palate, uvula, fauces visible, III: Soft palate, base of uvula visible, IV: Only hard palate visible). Grade I was considered better outcomes. | Intraoperative anesthetic induction | 
| Thyromental Distance | The thyromental distance was measured. | Intraoperative anesthetic induction | 
| Postoperative Sore Throat Measured Using Visual Analogue Scale | Postoperative sore throat will be measured using visual analogue scale (0:no pain, 100: worst pain imaginable) | at 1, 24 hr postoperatively | 
| Mean Blood Pressure | Mean blood pressure is measured before and 2 min after intubation. | Intraoperative intubation | 
| Heart Rate | Heart rates are measured before and 2 min after intubation. | Intraoperative intubation | 
| Airway Injury | Larynx injury is assessed. | Intraoperative intubation | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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intubation, stylet, videolaryngoscope