Quality of Life in Patients With Bladder Cancer

Study Overview
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Brief Summary
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The purpose of this study is to learn about the quality of life of people living with bladder cancer. We are interested in learning about how the treatments for bladder cancer affect people. We plan to use the findings from this study to help doctors provide better care and information to patients with bladder cancer.

Official Title
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A Prospective Study of Quality of Life in Patients With Bladder Cancer

Conditions
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Bladder Cancer

Intervention / Treatment
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* Behavioral: Quality Of Life questionnaires


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All patients (male and female) who are diagnosed with bladder cancer Patients must be scheduled for radical cystectomy and urinary diversion are and/or being evaluated for neo-adjuvant chemotherapy prior to a planned cystectomy. Participants must be able to speak English. Participants must be able to provide informed consent. Participants must be 18 years of age or older to enroll. Participant may be eligible for and may receive neoadjuvant or adjuvant chemotherapy. Participant may have had intravesicle chemotherapy or immunotherapy (BCG, Interferon). Exclusion Criteria: Subjects may be excluded from the study based on the following criteria: Follow-up care not obtained at MSKCC. Metastatic disease at diagnosis.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 99 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| 1<br>new patients with bladder cancer and/or are scheduled for radical cystectomy and urinary diversion | Behavioral: Quality Of Life questionnaires<br>* All patients who agree to participate will be interviewed using a baseline idiographic quality of life assessment prior to surgery and at approximately 6, 12, 18 and 24 months postoperatively. All patients will also be asked to respond to a questionnaire including all standard measures (closed-ended, multiple choice items) before surgery and at approximately 3, 6, 12, 18 and 24 months post-surgery.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prospectively characterize the impact of radical cystectomy and different urinary diversions on quality of life of bladder cancer patients. |  | conclusion of study | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Compare various standard and idiographic measures of QOL, to determine their relative contributions in accounting for variance in key outcome criteria and prediction of patient QOL at subsequent assessment points. |  | conclusion of study | 
| Examine how patients react to more in-depth probing of the interview associated with idiographic assessment. |  | conclusion of study | 
| Develop a predictive model of QOL after radical cystectomy & urinary diversion using the data from idiographic and standard QOL measures. This model can ultimately be used in office based practice to guide treatment planning with each patient. |  | conclusion of study | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Quality of Life, Questionnaires, 08-076