Speech Analysis as a Diagnostic Tool for Mild Traumatic Brain Injury

Study Overview
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Brief Summary
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The waveform assessment of an athlete's speech production has a high probability of showing abnormalities after brain injury (concussions) which could be used not only for diagnosis of the concussion, but for recovery of the brain. The aim of this study is to investigate this possibility using the Cobweb automated application system for acoustic processing.

Detailed Description
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Concussions affect cognitive and fine muscle motor control, and these changes will be reflected in the acoustic characteristics of the vowels being produced. The methods to identify and analyze the acoustics of vowels will greatly extend the detailed understanding of vowels produced after a concussion. The identification of the changes in formant frequencies, pitch, and duration will provide the means to use these parameters as an automated diagnostic tool. The waveform assessment of the athlete's speech production has a high probability of showing brain abnormalities immediately after a suspected or diagnosed concussion at the venue of the athletic sport. The aim of this study assessment is to investigate this possibility using the Cobweb system and greatly enhance the ability to diagnose a concussion in a timely manner to remove the athlete from practice or play.

Official Title
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Utilization of Speech Analysis as a Diagnostic Tool to Objectively Evaluate Early Signs of Mild Traumatic Brain Injury: A Pilot Study

Conditions
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Concussion

Intervention / Treatment
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* Other: Voice recording


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All patients diagnosed or suspected of having a sports concussion seen in a clinical setting Ages 6 -21 Exclusion Criteria: Patients who have physical injuries to their lips, tongue or oral cavity will be excluded until they have healed. Patients with hearing or speech abnormalities who cannot consistently produce the stimulus materials. Non-native speakers who cannot read the materials or produce the stimuli consistently. Patients who cannot read the materials or produce the stimuli consistently due to their age.

Ages Eligible for Study
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Minimum Age: 6 Years
Maximum Age: 21 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Voice recording<br>Subjects voices were recorded as they spoke specific words | Other: Voice recording<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in formant frequencies | 1. Changes in formant frequencies F0,F1,F2,F3 in patients following concussion to recovery time. | 2 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes in duration of speech production | Changes in duration of speech production in patients following concussion to recovery time . | 2 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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concussion, athlete, speech analysis