Risk Factors for Endometrial Cancer in Black Women

Study Overview
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Brief Summary
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RATIONALE: Learning about the risk factors for endometrial cancer in black women may help the study of endometrial cancer in the future. PURPOSE: This clinical trial is studying risk factors for endometrial cancer in black women.

Detailed Description
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OBJECTIVES: Establish and evaluate procedures for conducting a hospital-based case-control study of risk factors for endometrial cancer in black women. OUTLINE: This is a multicenter study. Participants complete questionnaires about lifestyle factors and their usual diet and measure their waist and hips. Saliva or buccal specimens are collected for future research. PROJECTED ACCRUAL: A total of 30 cases and 30 controls will be accrued for this study.

Official Title
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Endometrial Cancer in Black Women

Conditions
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Endometrial Cancer

Intervention / Treatment
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* Other: questionnaire administration
* Other: study of socioeconomic and demographic variables
* Procedure: evaluation of cancer risk factors


Participation Criteria
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Eligibility Criteria
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DISEASE CHARACTERISTICS: Cases Diagnosed with endometrial cancer within the past year Self-identified as being black, African-American, black Hispanic, African, or Afro-Caribbean Healthy controls Self-identified as being black, African-American, black Hispanic, African, or Afro-Caribbean No history of endometrial or other cancer (except non-melanoma skin cancer) No prior hysterectomy PATIENT CHARACTERISTICS: Speak English No medical condition that would make it difficult to complete the interview PRIOR CONCURRENT THERAPY: See Disease Characteristics

Ages Eligible for Study
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Minimum Age: 21 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| case<br>Participants complete questionnaires about lifestyle factors and their usual diet and measure their waist and hips. Saliva or buccal specimens are collected for future research. | Other: questionnaire administration<br> <br> Other: study of socioeconomic and demographic variables<br> <br> Procedure: evaluation of cancer risk factors<br> <br> |
| control<br>Participants complete questionnaires about lifestyle factors and their usual diet and measure their waist and hips. Saliva or buccal specimens are collected for future research. | Other: questionnaire administration<br> <br> Other: study of socioeconomic and demographic variables<br> <br> Procedure: evaluation of cancer risk factors<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number and percentage of potential cases and controls approached who are found to be eligible for the study and reasons for being ineligible (including language) |  | 2 years | 
| Number and percentage of cases and controls approached who sign informed consent |  | 2 years | 
| Number and percentage of cases and controls who complete each part of the study (main questionnaire, diet questionnaire, saliva/buccal specimen) |  | 2 years | 
| Proportion of questions with missing data |  | 2 years | 
| Interviewer's evaluation of interview quality and respondent cooperation |  | 2 years | 
| Number and percentage of cases who are willing to have tumor specimens used for future research |  | 2 years | 
| Characteristics of cases and controls (demographics, main risk factors, and use of health care and screening) |  | 2 years | 
| Proportion of participants who rate the study positively on each measure in the post-interview assessment and respondents' suggested changes to the study |  | 2 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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endometrial cancer, risk factors, questionnaire, 07-093