Treatment of Primary Type I Pterygia With Argon Laser

Study Overview
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Brief Summary
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Introduction: Pterygium is a wing shape degenerative and hyperplastic growth of the bulbar conjunctiva extending onto the cornea, most commonly on the nasal side. Management of pterygium can be medical, surgical or combined. Alternative treatments as photocoagulation of blood vessels of the pterygium, have been described, especially in recurrent pterygia. Objectives: To determine whether Argon laser treatment reduces the symptoms and pterygium size in primary type I pterygia patients when compared with medical treatment. Subjects and Methods: Prospective, comparative and interventional study. Patients with type I pterygia in both eyes were included. The eyes were randomly divided to receive either Argon laser treatment or only topical medical treatment

Detailed Description
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Pterygium is a wing shape degenerative and hyperplastic growth of the bulbar conjunctiva extending onto the cornea, most commonly on the nasal side. Management of pterygium can be medical, surgical or combined. Alternative treatments as photocoagulation of blood vessels of the pterygium, have been described, especially in recurrent pterygia. To determine whether Argon laser treatment reduces the symptoms and pterygium size in primary type I pterygia patients when compared with medical treatment. Subjects and Methods: Prospective, comparative and interventional study. Patients with type I pterygia in both eyes were included. The eyes were randomly divided to receive either Argon laser treatment or only topical medical treatment

Official Title
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Treatment of Primary Type I Pterygia With Argon Laser

Conditions
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Pterygium

Intervention / Treatment
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* Other: Sham
* Procedure: Argon Laser Treatment


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients who had had symmetric type I pterygia in both eyes Assessments for the 6 month follow-up period after argon laser treatment Exclusion Criteria: Patients with diabetes Mellitus, collagenopathies, previous ocular surgeries, and pregnant patients

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Sham Comparator: Sham of Argon Laser Treatment<br>Slit lamp light exposure | Other: Sham<br>* This group will not receive argon laser medical treatment; instead, they will be only exposed to the slit lamp light.<br>|
| Experimental: Argon Laser Treatment<br>Argon Laser Treatment | Procedure: Argon Laser Treatment<br>* This group will receive argon laser medical treatment to the body and head of pterygium<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pterygia measurements | Measurements were performed according to Welch et al. modified technique as following: the distance in millimeters from the limbus to the apex of the lesion on the cornea (horizontal length) was performed using the slit-lamp beam (BQ 900, Haag-Streit, Koeniz, Switzerland). A standard magnification of 16 was used and the variable aperture was focused from the limbus to the apex. | 1 year |