Selective Laser Trabeculoplasty After Failed Phacoemulsification With Eximer Laser Trabeculectomy

Study Overview
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Brief Summary
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The aim of this study is to evaluate the efficacy of selective laser trabeculoplasty after a prior failed phacoemulsification and Eximer Laser Trabeculectomy.

Detailed Description
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This study evaluates the efficacy of selective laser trabeculoplasty after a failed combined procedure of phacoemulsification cataract extraction with intraocular lens implantation plus Eximer Laser Trabeculectomy in open angle glaucoma or ocular hypertension. The success of SLT will be determined by the intraocular pressure and number of hypotensive drugs.

Official Title
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Effectiveness of Selective Laser Trabeculoplasty (SLT) After Failed Phacoemulsification Cataract Extraction Combined With Eximer Laser Trabeculectomy (Phaco-ELT) in Open Angle Glaucoma and Ocular Hypertension

Conditions
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Open Angle Glaucoma, Ocular Hypertension, Cataract

Intervention / Treatment
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* Procedure: Selective Laser Trabeculoplasty


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: diagnosis of open angle glaucoma or ocular hypertension and diagnosis of cataract Exclusion Criteria: diagnosis of angle closure glaucoma any optic neuropathy other than glaucoma

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: SLT arm<br>Patient receiving 'Selective Laser Trabeculoplasty' (SLT) due to failed Phacoemulsification Cataract Extraction with Intraocular Lens Implantation combined with Eximer Laser Trabeculectomy (phaco-ELT) in Open Angle Glaucoma and Ocular Hypertension to control intraocular pressure and/or glaucoma progression. | Procedure: Selective Laser Trabeculoplasty<br>* Selective Laser Trabeculoplasty is a laser treatment procedure to enhance trabecular aequous humor outflow and thus decrease intraocular pressure.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Efficacy intraocular pressure | Efficacy as measured by decrease in intraocular pressure from baseline | t0 and t=12 month | 
| Efficacy medication | as measured by decrease in number of used hypotensive medications | t0 and t=12 month | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Efficacy visual acuity | Efficacy as increase in best corrected visual acuity | t0 and t=12 month | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Open angle glaucoma, Ocular hypertension, Cataract, Selective Laser Trabeculoplasty, Eximer Laser Trabeculectomy, Phacoemulsification Cataract Extraction