Injection Rate and Erector Spinae Plane Block

Study Overview
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Brief Summary
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To evaluate the effect of injection rate on the block sensory level in the ESP block.

Detailed Description
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Many women experience severe acute postoperative pain after breast cancer surgery. Regional techniques are frequently used as a part of multimodal analgesia in breast surgery. Ultrasound-guided erector spinae plane (ESP) block is a preferred method to reduce the postoperative opioid requirement for postoperative pain management. In this study, we aimed to evaluate the effect of injection rate on the block sensory level in the ESP block.

Official Title
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Effect of Injection Rate on the Block Sensory Level in the Erector Spine Plane Block

Conditions
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Postoperative Pain, Breast Surgery

Intervention / Treatment
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* Procedure: Standard group
* Procedure: Long group


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: aged between eighteen and sixty-five ASA I-III undergo elective breast cancer surgery Exclusion Criteria: under 18 years of age or over 65 years of age ASA IV and above declined to give written informed consent contraindications of peripheral blocks or local anesthetic infiltration history of allergy against local anesthetics chronic pain history history of hepatic, neuromuscular, cardiac and/or renal failure infection at the injection site

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Standard group<br>standard injection rate will be applied | Procedure: Standard group<br>* Ultrasound-guided ESP block with 20 mL %0.375 bupivacaine will be administered at a standard injection rate.<br>|
| Active Comparator: Long group<br>long injection rate will be applied | Procedure: Long group<br>* Ultrasound-guided ESP block with 20 mL %0.375 bupivacaine will be administered at a long injection rate.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Block sensory level | Number (average) of dermatomes with sensory block with pinprick and cold methods after the ESP block | 12 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative tramadol consumption | Postoperative tramadol consumption will be recorded at 24 hours | 24 hours | 
| Assesment of postoperative analgesia | Post operative pain scores will be assessed using a numerical rating scala (NRS) (from 0=no pain, to10= worst pain imaginable). | 24 hours | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Erector spinae plane (ESP) block, Postoperative Pain, Breast Surgery