Predicting Dropout and Outcome From Neuropsychological Functions in SUD Patients

Study Overview
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Brief Summary
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The aim of this project is to gain a more specific understanding of how different cognitive profiles predict residential treatment drop-out, treatment retention and post-treatment outcome in a population with Substance Use Disorder.

Detailed Description
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This project collects the neuropsychological profile of residential SUD patients, in addition to treatment length, exit reason, hospital journal data and post-treatment clinical outcome data. The project aims to identify clinically relevant neurocognitive domains that predict treatment dropout and post-treatment clinical outcome. This will make it possible for future clinicians to focus their effort on neurocognitive functions most relevant for this particular patient group. RESEARCH QUESTIONS: What neurocognitive domain (and sub-domain) are the strongest predictor of treatment drop-out and retention? What neurocognitive domain (and sub-domain) are the strongest predictor of post-treatment clinical outcome variables such as drug use, health and social integration. Will data on treatment length, age, gender, substance abuse history or psychiatric co-morbidity predict outcome independently, or in interaction with, the neuropsychological profile? This longitudinal prospective cohort study aims for a continuous collection of neuropsychological data baseline and post-treatment follow-up data until 2030.

Official Title
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Predicting Early Treatment Termination (Dropout) and Post-treatment Clinical Outcome From Neuropsychological Functions in Abstinent Substance Use Dependent (SUD) Patients

Conditions
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Substance Use Disorder (SUD)

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Substance Use Disorder (SUD) patients. 18 years or older. Qualified to consent to research participation. Able to speak and write in Norwegian. Exclusion Criteria: Not qualified to consent to research participation. Insufficient understanding of Norwegian.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Exit reason | Reason for terminating residential SUD treatment (Treatment completed or Drop-out) | On average 3 months | 
| Treatment retention | Number of days in treatment | On average 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Substance use | DUDIT (Drug Use Disorders Identification Test) | 1 year after neuropsychological assessment | 
| Psychological distress | SCL-10 (Symptom Checklist) | 1 year after neuropsychological assessment | 
| Quality of Life | QoL-5 (Quality of Life) | 1 year after neuropsychological assessment | 
| ADHD symptoms | ASRS (ADHD Self-Report Scale) | 1 year after neuropsychological assessment | 
| Income | Nature of income | 1 year after neuropsychological assessment | 
| Housing | Nature of present accommodation | 1 year after neuropsychological assessment | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Drop-out, Neuropsychology, Cognition, Follow-up