Activity Levels in Bone Marrow Transplant Patients

Study Overview
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Brief Summary
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Participants in this study will be receiving a bone marrow transplant. This study is designed to evaluate correlations between activity levels and length of stay, quality of life, and hand grip strength.

Detailed Description
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Participants in this study will be receiving a bone marrow transplant. Participants will be given actigraphs to wear around their waists starting 3 weeks prior to bone marrow transplants until they are discharged from the hospital. Participants will be asked to complete quality of life questionnaires and hand grip tests at three separate time points during their hospitalizations. All data gathered from these activities will be compared with patients' activity levels gathered from the actigraphs both before and during the hospitalization. This study is designed to determine the relationship between activity levels and length of stay, quality of life, and hand grip strength.

Official Title
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Activity Levels in Bone Marrow Transplant Patients

Conditions
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Bone Marrow Transplant

Intervention / Treatment
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* Device: Actigraph
* Other: Grip strength test


Participation Criteria
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Eligibility Criteria
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Patients who will be receiving a bone marrow transplant are eligible for this study

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 99 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Device: Actigraph|Actigraphs are non-invasive, wearable devices that measure activity levels using an accelerometer|
|Other: Grip strength test|The purpose of this test is to measure the maximum isometric strength of the hand and forearm muscles|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To determine the correlation between activity levels and length of stay in hospital | Participants will be given actigraphs to wear around their waists starting 3 weeks prior to bone marrow transplants until they are discharged from the hospital. Activity prior to and during hospitalization will be correlated with length of stay. | From study intitiation for up to 5 years | 
| To determine the correlation between activity levels and quality of life | Participants will be given actigraphs to wear around their waists starting 3 weeks prior to bone marrow transplants until they are discharged from the hospital. They will be provided with quality of life questionnaires at three time points during hospitalization. Activity prior to and during hospitalization will be correlated with quality of life | From study intitiation for up to 5 years | 
| To determine the correlation between activity levels and hand grip strength | Participants will be given actigraphs to wear around their waists starting 3 weeks prior to bone marrow transplants until they are discharged from the hospital. Hand grip strength will be measured at three time points during hospitalization. Activity prior to and during hospitalization will be correlated with hand grip strength. | From study intitiation for up to 5 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To determine barriers to activity for patients recovering from bone marrow transplantation and design an intervention to increase activity levels in patients post-transplantation | Barriers to physical activity will be determined using a validated questionnaire at three time points during hospitalization. | From study intitiation for up to 5 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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leukemia, multiple myeloma, myelodysplastic syndrome, stem cell transplant