Purse String Suture for the Closure of Large Thyroidectomy Resulted in Better Cosmetics

Study Overview
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Brief Summary
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Thyroidectomy for large thyroid tumor poses a problem of cosmetics, especially in terms of wide post-operative scar and prominent neck wrinkles. In this manuscript, we performed purse-string suture for the first time for the closure of skin defect after thyroidectomy of large thyroid tumors which resulted in better cosmetics as compared to the conventional suturing method.

Detailed Description
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Increasing demand for better cosmetics following thyroidectomy for large thyroid tumor of > 6 cm diameter created a necessity to find an alternative to the conventional technique (CT), which could be addressed by purse string technique (PST). A non-randomized controlled trial was conducted to new thyroid tumor patients at Cipto Mangunkusumo Hospital (RSCM) from October 2013 until December 2014. Thirty patients grouped into two intervention arms of thyroidectomy with PST and CT were assessed for post-operative scar outcomes.

Official Title
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Purse String Suture for the Closure of Large Thyroidectomy Resulted in Better Cosmetics

Conditions
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Thyroidectomy

Intervention / Treatment
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* Procedure: Purse string technique
* Procedure: Conventional technique


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: New cases of thyroid tumor in Doctor Cipto Mangunkusumo General Hospital Tumor diameter > 6 cm Exclusion Criteria: Previous surgery in the anterior neck area Local involvement of lymph nodes requiring nodes dissection
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Non-randomized controlled study
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Purse String Technique<br>Thyroidectomy closure is performed using purse string technique. | Procedure: Purse string technique<br>* Thyroidectomy closure is performed using purse string suturing technique.<br>* Other names: PST;|
| Active Comparator: Conventional technique<br>Thyroidectomy closure is performed using conventional technique. | Procedure: Conventional technique<br>* Thyroidectomy closure is performed using conventional suturing technique.<br>* Other names: CT;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Length of scar | Length of scar in milimeter | 8 to 12 weeks following thyroidectomy | 
| Width of scar | Width of scar in milimeter | 8 to 12 weeks following thyroidectomy | 
| Wrinkle | Presence of wrinkle | 8 to 12 weeks following thyroidectomy | 
| Patient's satisfaction | Patient's satisfaction assessed using Likert scale of 1 to 10 | 8 to 12 weeks following thyroidectomy | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Duration of surgery | Duration of surgery in minutes | During surgery | 
| Bleeding | Volume of bleeding during surgery in cc | During surgery | 
| Post operative hospital stay | Post operative hospital stay | 1 week following thyroidectomy | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Large thyroid, purse string suture, thyroidectomy