Dual Energy X-ray Absorptiometry (DXA) Comparison Hip Resurfacing Versus Total Hip Arthroplasty (THA)

Study Overview
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Brief Summary
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This study compares the change (loss) of bone mineral density (BMD) that occurs in the proximal femur after hip resurfacing and total hip replacement.

Detailed Description
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This study compares the change (loss) of bone mineral density (BMD) that occurs in the proximal femur after hip resurfacing and total hip replacement. The goal is to evaluate the bone loss in the proximal femur resulting from hip resurfacing surgery and to compare this to the bone loss in the proximal femur resulting from total hip arthroplasty.

Official Title
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A Dual Energy X-Ray Absorptiometry Comparison Of Periprosthetic Bone Loss Between Patients Undergoing Hip Resurfacing Surgery And Total Hip Arthroplasty

Conditions
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Osteoarthritis, Hip

Intervention / Treatment
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* Device: Hip Resurfacing
* Device: Total Hip Arthroplasty


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age of at least 20 years Osteoarthritis Elective Total Hip Arthroplasty / Resurfacing Signed Informed Consent Exclusion Criteria: Osteoporosis Revisions Femoral dysplasia Trochanteric osteotomy Inflammatory arthritis Breast-feeding, pregnancy, or women of child-bearing potential without documentation of a negative pregnancy test and not utilizing contraception Patients with a history of having taken or currently taking PTH, fluoride therapy or strontium ranelate or patients taking other chronic medications that in the Investigator's opinion are known to affect bone mineral density in a substantial way Patients with severe medical condition(s) that in the view of the Investigator prohibits participation in the study Use of any other investigational agent in the last 30 days

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Hip Resurfacing<br> | Device: Hip Resurfacing<br> <br> |
| Total Hip Arthroplasty<br> | Device: Total Hip Arthroplasty<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bone Mineral Density | To evaluate the bone loss in the proximal femur resulting from hip resurfacing surgery and to compare this to the bone loss in the proximal femur resulting from total hip arthroplasty. | Baseline, 6 weeks, 6 months, 1, 2, 3, 4, and 5 years post-operative | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Harris Hip Score | Hip functional outcomes will be assessed using the Harris Hip Score | Pre-operative, 6 weeks, 6 months, 1, 2, 3, 4, and 5 years post-operative | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Total Hip Replacement, Hip Resurfacing, Femoral Remodeling, Bone Loss, Bone Mineral Density, BMD, DXA, DEXA, THA