The Effect of Family History on Insomnia During Sobriety in Alcoholics

Study Overview
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Brief Summary
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The investigators intend to assess the following: the efficacy of CBTi in treating insomnia during recovery, does a family history of alcoholism moderate the insomnia symptoms, does an improvement in insomnia lead to a decrease in impulsivity.

Detailed Description
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The primary goals of this pilot study are the following: a) to assess for the difference in improvement insomnia, after 8 weeks of treatment with recommended CBTi, in Veterans with alcohol dependence during early recovery, The secondary goals include the following: to assess for any change in the alcohol consumption indices between the groups after 8 weeks of CBTi, to assess for change in psychiatric symptoms of mood and anxiety across the groups, to assess for differences in insomnia in subjects, with and without a first degree family history of alcohol dependence, to evaluate for any change in impulsivity-related measure with insomnia treatment.

Official Title
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The Effect of Family History on Insomnia During Sobriety in Alcoholics

Conditions
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Insomnia

Intervention / Treatment
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* Behavioral: Cognitive Behavioral Therapy for Insomnia (CBT-I)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Presence of insomnia currently DSM IV diagnosis of alcohol dependence within the past year Not in acute alcohol withdrawal and within a year of sobriety from alcoholism Patients with moderate-severe sleep apnea compliant on their PAP device Can speak, understand and print in English. Is capable of giving written informed consent. Exclusion Criteria: Dependence on psychoactive substance (excluding alcohol, nicotine and cannabis) in the past 12 months, or evidence of chronic opiate use. Unstable/serious psychiatric condition e.g. schizophrenia, bipolar disorder. Unstable or serious medical/neurologic illness Severe cognitive impairment Untreated moderate - severe obstructive sleep apnea

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: CBT-I<br>Cognitive Behavioral Therapy for Insomnia | Behavioral: Cognitive Behavioral Therapy for Insomnia (CBT-I)<br>* Behavioral management of insomnia<br>|
| No Intervention: Monitor Only (M.O.)<br> | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Insomnia Severity Index total score | There will be post-treatment follow up at 3 months and 6 months. | 8 weeks. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Time Line Follow Back measure | There will be post-study follow-up at 3 months and 6 months also. | 8 weeks. |