Oocyte Cryopreservation

Study Overview
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Brief Summary
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The purpose of this investigation is to offer the opportunity for young women to cryopreserve (freeze) their oocytes (eggs) for use with IVF at a later point in time.

Official Title
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Oocyte Cryopreservation

Conditions
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Fertility

Intervention / Treatment
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* Procedure: vitrification of oocytes


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: women between the ages of 18 and 42 election to preserve fertility by freezing eggs Exclusion Criteria: women over the age of 43 patient unwilling to sign informed consent

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 42 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: oocyte freezing<br>includes any women who elects to preserve her fertility by vitrifying her unfertilized eggs. | Procedure: vitrification of oocytes<br>* eggs will be preserved via vitrification the day they are retrieved from the participant<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Successful pregnancy | Eggs will be frozen via vitrification for those females electing to preserve their fertility; patients will return following an unspecified time period, when they are ready to use their frozen eggs. At that time, the eggs will be thawed and fertilized (with the sperm source of the participant's choice) to create embryos. This time frame will be unique to each individual; however, the Center has a policy whereby no embryo transfer will be performed beyond the age of fifty (50). | until the patient reaches 50 years of age | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| oocyte survival | the number of eggs that successfully survive the frozen-thawing procedure (vitrification). | up to 50 years of age | 
| fertilization | to calculate the rate for the number of oocytes that are successfully fertilized (via ICSI) following survival of the frozen-thaw procedure. | up to 50 years of age | 
| blastocyst formation | calculates the number of successfully fertilized embryos that grow into blastocysts (day 5 of culture), created from eggs that underwent and survived vitrification. | up to 50 years of age | 
| implantation | to determine the implantation rate of embryos that were created from vitrified oocytes. | up to 50 years of age | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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vitrification, egg freezing, oocyte cryopreservation, female fertility potential, fertility preservation, Fertility preservation, female