Effect of Home Exercise Activity on Cortisol and Depression in COPD During the Pandemic COVID

Study Overview
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Brief Summary
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exercise activity during the COVID pandemic is appreciated to be conducted in home especially for chronic chest diseases as chronic obstructive pulmonary disease (COPD) to reduce the chance of viral contamination during the COVID-19 pandemic.

Detailed Description
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40 COPD men will be divided to exercise group (20 patients) and control group (20 patients): the exercise group will receive a exercise session contains a fifty minutes exercise training at home with moderate intensity on the available training devices as bicycle or treadmill in addition to 30 minutes of exercising of upper and lower limb, the session will be repeated three times per week for eight weeks. The control group will not be trained

Official Title
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Effect of Home Exercise Activity on Cortisol and Depression in COPD Patients During the Pandemic COVID-19

Conditions
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Chronic Obstructive Pulmonary Disease

Intervention / Treatment
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* Behavioral: exercise group
* Other: control group


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: stable COPD patients patients who will have a training device as bicycle or treadmill in home Exclusion Criteria: diabetic patients renal patients. liver diseases

Ages Eligible for Study
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Minimum Age: 50 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Exercised group<br>the exercise group (20 patients) will receive a exercise session contains a fifty minutes exercise training at home with moderate intensity on the available training devices as bicycle or treadmill in addition to 30 minutes of exercising of upper and lower limb, the session will be repeated three times per week for eight weeks. | Behavioral: exercise group<br>* the exercise group (20 patients) will receive a exercise session contains a fifty minutes exercise training at home with moderate intensity on the available training devices as bicycle or treadmill in addition to 30 minutes of exercising of upper and lower limb, the session will be repeated three times per week for eight weeks.<br>|
| Other: control group<br>The control group will not be trained | Other: control group<br>* the control group will not be trained<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| cortisol | it will be measured in plasma | It will be measured after eight weeks of training | 
| hospital anxiety and depression scale | this a questionnaire that will assess anxiety and depression in COPD patients | It will be measured after eight weeks of training | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| pulmonary function test | it will be a measurement for lung volume and capacities | It will be measured after eight weeks of training | 
| Interleukin-8 | It is an inflammatory marker in plasma | It will be measured after eight weeks of training | 
| body mass index | it will measure body mass changes | It will be measured after eight weeks of training | 
| six minute walking test | it assess functional capacity | It will be measured after eight weeks of training | 
| St. George's respiratory questionnaire | It assess the effect of COPD on general quality of life | It will be measured after eight weeks of training |