Clinical Predictive Factors of Success of Hysteroscopic Endometrial Ablation/Resection

Study Overview
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Brief Summary
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To determine the predictive factors of endometrial ablation failure in the management of uterine bleeding.

Detailed Description
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This is a retrospective cohort study for women who have been treated with Thermal endometrial ablation due to uterine bleeding. The main purpose of this study is to demonstrate the possible risk factors associated with endometrial ablation failure causing patients to need subsequent gynecological procedures or undergoing hysterectomy for definitive treatment. Such efforts are made in order to anticipate the morbidity and mortality associated with patients in such conditions and to effectively stratify those patients to appropriate treatment techniques.

Official Title
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Clinical Predictive Factors of Success of Hysteroscopic Endometrial Ablation/Resection; Retrospective Study at a Tertiary University Hospital

Conditions
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Uterine Bleeding, Treatment Failures, Prognostic Factors

Intervention / Treatment
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* Procedure: Endometrial Ablation
* Procedure: Repeated gynecological procedure


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All patients who had their endometrial ablation at Jordan University Hospital. Exclusion Criteria: Patients whose index ablation or subsequent re-intervention could not be confirmed in detailed operative reports were excluded
Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients who had successful endometrial ablation<br>Patients included in this group experienced abnormal uterine bleeding and underwent endometrial ablation. Successful ablation was defined as not undergoing subsequent gynecological procedures such as hysterectomy for any benign indication, D&C or repeat ablation within 36 months after the endometrial ablation. | Procedure: Endometrial Ablation<br>* Thermal endometrial ablation<br>|
| Patients who had unsuccessful endometrial ablation<br>Patients included in this group experienced abnormal uterine bleeding and underwent endometrial ablation. Unsuccessful ablation was defined as undergoing subsequent gynecological procedures such as hysterectomy for any benign indication, D&C or repeat ablation within 36 months after the endometrial ablation. | Procedure: Endometrial Ablation<br>* Thermal endometrial ablation<br>Procedure: Repeated gynecological procedure<br>* subsequent gynecological procedures such as hysterectomy for any benign indication, D&C or repeat ablation.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Clinical Predictive factors of successful endometrial ablation | the outcome of hysteroscopic endometrial ablation whether it was a failure or a success; failure was defined as persistent of heavy bleeding after the ablation. | from September 2016 through February 2022 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The failure rate of endometrial ablation for uterine bleeding | To find the failure rate of endometrial ablation that is done for uterine bleeding | from September 2016 through February 2022 | 
| Subsequent gynecological procedures after failed ablation | To find the subsequent gynecological procedures that patients with unsuccessful ablation had | from September 2016 through February 2022 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Endometrial Ablation Technique, Uterine Bleeding, Treatment Failures, Prognostic Factors