Evaluate the Predictive Impact of the MEESSI Score

Study Overview
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Brief Summary
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Our primary purpose is to assess MEESSI score in predicting mortality and readmission of patients managed for acute heart failure (AHF) in Emergency Department. European Society of Cardiology recommend risk stratification for patients with AHF.

Detailed Description
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Improved risk stratification of acute heart failure (AHF) in the emergency department (ED) may help physicians' decisions regarding patient admission or early discharge disposition. The MEESSI-AHF (Multiple Estimation of risk based on the Emergency department Spanish Score In patients with AHF) score was developed to predict 30-day mortality in patients presenting with AHF EDs in Spain. Whether it performs well in other countries is unknown. The MEESSI-AHF risk model includes 13 variables readily available on arrival to Emergency Department. The 40% of patients classified as LOW RISK (30-day mortality: <2%) should be considered as potential candidates to be early discharged from Emergency Department without admission after adequate response to initial treatment. The 10% of patients classified as VERY HIGH RISK (30-day mortality: >2%) may clearly benefit from hospital admission. Objective: To externally validate the MEESSI-AHF score in another country.

Official Title
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Evaluate the Predictive Impact of the Meessi MEESSI Score for the Risk Stratification of Patients Admitted for Acute Heart Failure in Emergency Department

Conditions
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Emergencies, Heart Diseases

Intervention / Treatment
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* Diagnostic Test: MEESSI score


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Major patient Patient admitted to emergencies with final diagnosis of AHF according to the opinion of two emergency experts after consulting the data from the clinical examination, cardiac echocardiography, and BNP level. Subject who accept to participate in the research Exclusion Criteria: Patient who refuse to participate in the study Patient with coronary syndrome with ST segment elevation Other causes of dyspnea Impossibility of giving the patient informed information Pregnant woman

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 95 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: MEESSI score|The score aimed to predict the AHF patient's future in the month following management for ED|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| MEESSI score | predict the AHF patient's future in the month following management in ED with The MEESSI (Multiple Estimation of risk based on the Emergency department Spanish Score In patients with AHF).The MEESSI-AHF risk model includes 13 variables readily available on arrival to Emergency Department. The 40% of patients classified as LOW RISK (30-day mortality: <2%) should be considered as potential candidates to be early discharged from Emergency Department without admission after adequate response to initial treatment. The 10% of patients classified as VERY HIGH RISK (30-day mortality: >2%) may clearly benefit from hospital admission. | 30 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Re-admission rate [ Time Frame: 30 days ] | 30-day re-admission rate compared between the 4 risk categories defined by the MEESSI score | 30 days | 
| Mortality rate [ Time Frame: 30 days ] | Mortality rate at 30 days compared between the 4 risk categories defined by the MEESSI score | 30 days | 
| Sensitivity [ Time Frame: 30 days ] | Sensitivity, specificity and ROC curve of the MEESSI score in relation to the composite criterion according to the 4 risk categories | 30 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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MEESSI score, ACUTE HEART FAILURE