The Impact of Anterior Abdominal Wall Tissue Oxygenation During Pneumoperitoneum of Regional Anesthesia Methods

Study Overview
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Brief Summary
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During laparoscopic surgery, the abdomen is inflated with carbon dioxide for abdominal imaging and increased intraabdominal pressure affects intraabdominal structures and abdominal wall.

Detailed Description
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The investigators aimed to investigate the effects of regional anesthesia methods administered during laparoscopic cholecystectomy on abdominal wall oxygenation and postoperative pain scores.

Official Title
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Investigation the Effect of Regional Anesthesia Methods Anterior Abdominal Wall Tissue Oxygenation on Laparoscopic Cholecystectomy

Conditions
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Laparoscopy, Abdominal Wall, Regional Anesthesia

Intervention / Treatment
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* Device: regional oxymetry probe
* Procedure: Quadratus Lumborum block
* Procedure: Thoracic Epidural block


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients who were in the American Society of Anesthesiologists (ASA) I-III class Underwent laparoscopic cholecystectomy Exclusion Criteria: Previous surgeon surgeon Local anesthetic allergy, Bleeding is a diathesis disorder Mental impairment, Allergic to the drugs used, Patients who are not reluctant to participate in the study, Presence of infection in the block area, Patients whose body mass index is over 30

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: prospective,randomized
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Group A<br>The regional oxymetry probe will be placed in the abdominal region of the umbilicus in the middle clavicular line before the disease operation begins. | Device: regional oxymetry probe<br>* The regional oxymetry probe will be placed in the abdominal region of the umbilicus in the middle clavicular line before the disease operation begins.<br>* Other names: abdominal wall tissue oxygenation;|
| Active Comparator: Group E<br>Thoracic Epidural block +The regional oxymetry probe will be placed in the abdominal region of the umbilicus in the middle clavicular line before the disease operation begins. | Device: regional oxymetry probe<br>* The regional oxymetry probe will be placed in the abdominal region of the umbilicus in the middle clavicular line before the disease operation begins.<br>* Other names: abdominal wall tissue oxygenation;Procedure: Thoracic Epidural block<br>* Thoracic Epidural block with 20 ml %0.25 bupivacaine+The regional oxymetry probe will be placed in the abdominal region of the umbilicus in the middle clavicular line before the disease operation begins.<br>|
| Active Comparator: Group Q<br>Ultrasound guided unilateral anterior Quadratus Lumborum block +The regional oxymetry probe will be placed in the abdominal region of the umbilicus in the middle clavicular line before the disease operation begins. | Device: regional oxymetry probe<br>* The regional oxymetry probe will be placed in the abdominal region of the umbilicus in the middle clavicular line before the disease operation begins.<br>* Other names: abdominal wall tissue oxygenation;Procedure: Quadratus Lumborum block<br>* Ultrasound guided unilateral anterior Quadratus Lumborum block with 20 ml %0.25 bupivacaine+The regional oxymetry probe will be placed in the abdominal region of the umbilicus in the middle clavicular line before the disease operation begins.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| rso2 | The regional oxymetry probe will be placed in the abdominal region of the umbilicus in the middle clavicular line | peroperative 2 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual Analog Scale | Visual Analog Scale was used for pain.Pain intensity was measured using 0-10 cm visual analogue scale (VAS). (0=no pain, 10=intolerable pain) | Postoperative 24 hours | 
| tramadol consumption | tramadol consumption with PCA (patient-controlled analgesia ) device | Postoperative 24 hours | 
| additional analgesic use | additional analgesic use (paracetamol and NSAİD) | Postoperative 24 hours |