Diagnostic Study of Lateral Ligament Complex Injury of Ankle

Study Overview
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Brief Summary
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Comparative Study on Accuracy of Different Diagnostic Methods of Lateral Collateral Ligament Injury of Ankle

Detailed Description
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Background: The lateral ligament complex of ankle joint consisting of the anterior talofibular ligament (ATFL), the calcaneofibular ligament (CFL), and the posterior talofibular ligament (PTFL), is often injured by an ankle sprain. Improper diagnosis and treatment of lateral ligament complex injury are not only prone to recurrent sprain, pain, swelling and other symptoms, but also can lead to chronic lateral ankle instability, and osteoarthritis, which could seriously affect the joint motor function. Method and objective: This study is a prospective diagnostic test. By comparing the sensitivity and specificity of stress X-ray, B-ultrasound, Computed tomography (CT), and Magnetic resonance imaging (MRI), and analyzing the imaging manifestations and characteristics of different diagnostic methods of lateral chronic ankle instability, We aim to propose the criteria of the imaging diagnosis of lateral ankle ligament injury.

Official Title
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Comparative Study on Accuracy of Different Diagnostic Methods of Lateral Ligament Complex Injury of Ankle

Conditions
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Chronic Instability of Ankle Joint, Lateral Ligament Complex Injury of Ankle

Intervention / Treatment
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* Diagnostic Test: Stress radiography,Anterior drawer test,Stress ultrasound,Computed tomography, Magnetic resonance imaging,Arthroscopy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Chronic lateral ankle ligament injury due to ankle sprain in patients over 16 years of age. Exclusion Criteria: Acute and subacute injury of the lateral ligament complex of the ankle joint (less than 3 months), malalignment of ankle (more than 5 degrees), osteoarthritis (stage IV).

Ages Eligible for Study
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Minimum Age: 16 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| stable<br>The anterior drawer test and/or talar tilt test are negative and the ankle joint is stable. | Diagnostic Test: Stress radiography,Anterior drawer test,Stress ultrasound,Computed tomography, Magnetic resonance imaging,Arthroscopy<br>* All patients suspected chronic ankle instability, will perform an anterior drawer test, stress ultrasound, computed tomography, magnetic resonance imaging of ankle. Patients with chronic ankle instability will be recommended to perform an arthroscopic repair if non-operative treatment failed.<br>|
| slightly instable<br>The anterior drawer test and/or talar tilt test are slightly positive and the ankle joint is partially instable. | Diagnostic Test: Stress radiography,Anterior drawer test,Stress ultrasound,Computed tomography, Magnetic resonance imaging,Arthroscopy<br>* All patients suspected chronic ankle instability, will perform an anterior drawer test, stress ultrasound, computed tomography, magnetic resonance imaging of ankle. Patients with chronic ankle instability will be recommended to perform an arthroscopic repair if non-operative treatment failed.<br>|
| obviously instable<br>The anterior drawer test and/or talar tilt test is significantly positive, with significantly instable. The ankle joint is completely instable and can featured with dimple sign. | Diagnostic Test: Stress radiography,Anterior drawer test,Stress ultrasound,Computed tomography, Magnetic resonance imaging,Arthroscopy<br>* All patients suspected chronic ankle instability, will perform an anterior drawer test, stress ultrasound, computed tomography, magnetic resonance imaging of ankle. Patients with chronic ankle instability will be recommended to perform an arthroscopic repair if non-operative treatment failed.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| anterior talar translation and talar tilt | Assess the instability through stress X ray of the ankle | before operation | 
| length of ATFL and CFL in relax and stress position | Assess the instability through Ultrasound of the ankle | before operation | 
| Morphology of ATFL and CFL | Assess the ATFL and CFL through MRI of the ankle | before operation | 
| status of ATFL and CFL | evaluation of ATFL and CFL during operation | during operation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| avulsion fracture | avulsion fracture found by X ray, Ultrasound, CT or MRI | before operation | 
| osteophyte | osteophyte found by X ray, Ultrasound, CT or MRI | before operation | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Lateral Ligament complex, Ankle, Diagnostic Methods, Chronic Lateral Instability of Ankle