Bio Impedance Electrical Analysis to Predict Outcome After Cardiac Surgery

Study Overview
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Brief Summary
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Phase angle determined by bioelectrical impedance analysis is a strong prognostic factor in several medical areas as clinical nutrition, nephrology, infectious disease, oncology. Inflammation, frailty status and fluid overload can lead to a phase angle decreased. Some studies support its use for risk stratification in intensive care unit and other in preoperative for cardiac surgery. The investigators would like to evaluate its relevance for risk stratification at intensive care unit admission in the context of postoperative cardiac surgery with cardiopulmonary bypass.

Official Title
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Bio Impedance Electrical Analysis to Predict Outcome After Cardiac Surgery

Conditions
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Post Operative Care After Cardiac Surgery With Cardio Pulmonary Bypass

Intervention / Treatment
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* Diagnostic Test: Bioelectrical impedance analysis


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age higher than 18 Cardiac surgery with cardiopulmonary bypass Bioelectrical impedance analysis the day of the admission in intensive care unit Exclusion Criteria: Left ventricular assist device Limitations des thérapeutiques actives en place pour le patient Patient opposition to the use of his health data Invalid bioelectrical impedance analysis Advanced directives to withhold or withdraw life-sustaining treatment

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| BiPOCS group<br>All patients of our centers admitted for postoperative care after cardiac surgery with cardiopulmonary bypass and receiving a bioelectrical impedance analysis at the admission. | Diagnostic Test: Bioelectrical impedance analysis<br>* Segmental multi-frequency bioelectrical impedance analysis are carried out at all patient admitted to our ICU for postoperative care after cardiac surgery with cardiopulmonary bypass. Our objective is to evaluate the relevance of phase angle to predict mortality or a prolonged hospital length of stay. Phase angle is evaluated at ICU admission and will be compared to well-known prognostic scores computed in preoperative (EuroSCORE II) and at day one after surgery (SOFA, CASUS and SAPS II).<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Area under the receiver operating characteristic curve to predict a composite criterion including in-hospital mortality or prolonged hospital length of stay. | The phase angle's area under the receptor operative curve to predict a composite criteria evaluated at hospital discharge and combining: In hospital mortality Prolonged hospital length of stay, defined by an in hospital length of stay greater than the 75th percentile of length of stay in the study population | at 6 months after the cardiac surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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phase angle, cardiac surgery, cardiopulmonary bypass, risk stratification, outcomes