Intravenous Cannulation In Children During Sevoflurane Induction

Study Overview
=================
Brief Summary
-----------------
The early placement of an intravenous (iv) line in children anesthetized with halothane has been shown safe and acceptable compared with later placement. However, there's not well known with sevoflurane use (2). The aim of the investigator's study is to determine whether one should make iv attempts during the early induction period (at 60seconds) or lately (90 or 120 s) and waiting until the child receives additional sevoflurane inhalation anesthesia

Detailed Description
-----------------
the investigators conducted a prospective randomized study, after obtaining Institutional review board approval, which didn't require written parental consent. Children age 1-12 years, undergoing elective general anesthesia via an inhalation induction were randomized to one of three groups of 30 patients each one, for iv placement, either 60s (group E), 90 or 120 s (group L) following loss of lid reflex. Movement on iv placement and incidence of laryngospasm were determined. Difficulty with iv placement was also recorded. Statistical analysis included contingency testing, ANOVA, and non parametric testing. A P-value <0.05 was considered significant.

Official Title
-----------------
Intravenous Cannulation In Children During Sevoflurane Induction: Which Time is Adequate

Conditions
-----------------
Intravenous Cannulation, Sevoflurane Induction, Child

Intervention / Treatment
-----------------
* Other: Intravenous Cannulation (iv placement)


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: ASA I, II Age from 1 to 12 years old Ambulatory surgery under general anesthesia. Exclusion Criteria: Age <1 year or> 12 years non-ambulatory surgery, contraindication for induction with sevoflurane

Ages Eligible for Study
-----------------
Minimum Age: 1 Year
Maximum Age: 12 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Prospective randomized single blinded parallel group controlled study
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: 60s (group E)<br>Intravenous cannulation was released either 60 s following loss of lid reflex in group E | Other: Intravenous Cannulation (iv placement)<br>* The aim of our study is to determine whether one should make intravenous attempts placement during the early induction period (at 60seconds) or lately (90 or 120 s) and waiting until the child receives additional sevoflurane inhalation anesthesia.<br>|
| Active Comparator: 90 or 120 s (groupe L)<br>Intravenous cannulation was released either 90 or 120 s following loss of lid reflex in group L | Other: Intravenous Cannulation (iv placement)<br>* The aim of our study is to determine whether one should make intravenous attempts placement during the early induction period (at 60seconds) or lately (90 or 120 s) and waiting until the child receives additional sevoflurane inhalation anesthesia.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Movement on iv placement | Number of children who presented movement on iv placement | In the first 5 min after the anesthesic induction with sevoflurane | 
| laryngospasm | The incidence of laryngospasm | Time From Intravenous Cannulation to patient extubation | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Sevoflurane, Intravenous Cannulation, anesthesia, child