Retrospective Analysis of Performance and Treatment Data Collected for Genius SleddFlux Filter, Ultraflux AV 600 S Filter & Genius 90 Concentrates in Haemodialysis Patients

Study Overview
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Brief Summary
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Retrospective analysis of performance and treatment data collected for Genius SleddFlux Filter, Ultraflux AV 600 S Filter & Genius 90 Concentrates in acute haemodialysis, haemodynamically instable patients and chronic haemodialysis patients to analyse performance and treatment data from patients treated with the investigational device to evaluate the filter characteristics for aHD (Acute haemodialysis) patients to evaluate the improvement of kidney function for aHD patients

Official Title
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Retrospective Analysis of Performance and Treatment Data Collected for Genius SleddFlux Filter, Ultraflux AV 600 S Filter & Genius 90 Concentrates in Acute Haemodialysis, Haemodynamically Instable Patients and Chronic Haemodialysis Patients

Conditions
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Renal Failure, End Stage Renal Disease, Acute Renal Failure

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All patients with an indication for the extracorporeal blood treatment suffering from renal insufficiency who received all treatments, between January 2019 and December 2019, with the investigational devices have to be included in the study in chronological order. For aHD patients: availability of at least 3 of the 5 primary variables (daily urea, creatinine, potassium, ultrafiltration and effluent volume) for 50 % of the documented treatments. For cHD patients: availability of the ultrafiltration values for all treatments and at least one value for urea and creatinine per week Exclusion Criteria: Simultaneous use of another filter/adsorber for another form of therapy

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| aHD: Acute haemodialysis patients<br> | |
| cHD: Chronic haemodialysis patients<br> | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Daily values for urea, Unit: mg/dl or mmol/L | Acute haemodialysis patients | During the intervention | 
| Daily values for creatinine, Unit: mg/dl or mmol/ or µmol/L | Acute haemodialysis patients | During the intervention | 
| Daily values for potassium, Unit: mg/dl or mmol/ or µmol/L | Acute haemodialysis patients | During the intervention | 
| Ultrafiltration volume (UF) and Effluent volume (per treatment) | Acute haemodialysis patients | During the intervention | 
| Values for urea and creatinine (measured according to the clinical practice of the site) | Chronic haemodialysis patients | During the intervention | 
| Planned and delivered UF-volume (per treatment) | Chronic haemodialysis patients | During the intervention | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Hemodialysis, Genius system, Slow extended daily dialysis