Pakistan Flocculent Health Outcome Study

Study Overview
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Brief Summary
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This study is designed to evaluate the effect of different methods of drinking water treatment on the occurrence of diarrhea among children living in squatter settlements in Karachi, Pakistan, and the marginal benefit of adding handwashing to water treatment. 260 households will receive a new product which combines flocculation with chlorination to produce clearer, less chemically contaminated drinking water. 260 households will receive dilute sodium hypochlorite, i.e. bleach to treat their water. 260 households will receive soap and encouraged to wash their hands regularly. 260 households will receive both soap and the combination flocculation/chlorination water treatment. 260 households will continue their standard water treatment and handwashing practices. The households will be visited each week for 9 months, and the episodes of diarrhea from each child in the household recorded. The rate of diarrhea between the groups will be compared. At the end of 9 months, households who were part of the standard habits and practice group will receive a water storage vessel and disinfectant.

Official Title
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Pakistan Flocculent Health Outcome Study

Conditions
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Diarrhea

Intervention / Treatment
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* Other: handwashing
* Other: flocculent-disinfectant for water treatment
* Other: water treatment with sodium hypochlorite


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: households in study neighborhoods contain a child < 5 years old have access to water for handwashing Exclusion Criteria: participated in handwashing or drinking water treatment programs with HOPE previously
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Handwashing<br>participants received weekly, in-home handwashing promotion and soap as needed | Other: handwashing<br>* participants received weekly in-home handwashing promotion and soap as needed<br>|
| Experimental: handwashing and water treatment<br> | Other: handwashing<br>* participants received weekly in-home handwashing promotion and soap as needed<br>Other: flocculent-disinfectant for water treatment<br>* participants received a supply of flocculent-disinfectant product for water treatment and instruction in how to use it<br>|
| Experimental: Water treatment with sodium hypochlorite<br> | Other: water treatment with sodium hypochlorite<br>* participants received a supply of dilute sodium hypochlorite and instruction to treat drinking water with it<br>|
| Experimental: Water treatment with flocculent-disinfectant<br>participants received a supply of flocculent-disinfectant product and instruction to use it to treat drinking water | Other: flocculent-disinfectant for water treatment<br>* participants received a supply of flocculent-disinfectant product for water treatment and instruction in how to use it<br>|
| No Intervention: Control<br> | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| diarrhea longitudinal prevalence |  |  | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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diarrhea longitudinal prevalence, diarrhea, handwashing, point-of-use water treatment