Nutritional Supplements for Exercise Recovery

Study Overview
=================
Brief Summary
-----------------
This study will examine the effects of nutritional supplement on post-exercise muscle soreness as well as recovery of muscle strength and function.

Official Title
-----------------
Evaluation of Nutritional Supplements for Exercise Recovery

Conditions
-----------------
Post-exercise Muscle Soreness

Intervention / Treatment
-----------------
* Dietary Supplement: Supplement
* Other: Placebo


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Ability to consume supplement Willing to adhere to the study intervention regimen Willing to abstain from analgesics for duration of the study Agreement to adhere to Lifestyle Considerations Exclusion Criteria: Current use of NSAIDs Use of other nutritional or herbal supplements (e.g., protein powders, tart cherry juice, BCAAs, Vitamin D, probiotics, etc.) that have been shown to effect primary or secondary outcomes Presence of chronic diseases, including, but not limited to, cancer, HIV, hepatitis, cardiovascular, metabolic, and orthopedic conditions Weight > 350 pounds Pregnancy or lactation Known food allergies or sensitivities or dietary restrictions Habitual consumption of > 2 alcoholic drinks per day Febrile illness or antibiotic use within 1 month prior to baseline testing Treatment with another investigational drug or other intervention within 1 month Current smoker or tobacco use within 1 month Any condition(s) or diagnosis, both physical or psychological, that, in the opinion of the principal investigator or study physician, precludes participation and/or ability to consent Any other factor that, in the opinion of the principal investigator or study physician, would cause harm or increased risk to the participant or close contacts, or preclude the participant's full adherence with or completion of the study

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Placebo Comparator: Placebo<br>taste, color, and calorie-matched to supplement | Other: Placebo<br>* color, taste, and calorie-matched placebo<br>|
| Experimental: Supplement<br>Proprietary protein and fruit extract blend | Dietary Supplement: Supplement<br>* dietary supplement contain protein from milk and fruit extract<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| post-exercise muscle soreness | VAS score | 7 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| post-exercise muscle strength | countermovement jump performance | 7 days | 
| post-exercise muscle function | repetitive countermovement jumps | 7 days | 
| satiety | VAS scores | 4-5 hours | 
| sleep quality | sleep metrics, Fitbit | 15 days |