Study on Ventilation Distribution With Electrical Impedance Tomography for Paediatric Respiratory Failure

Study Overview
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Brief Summary
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Electrical impedance tomography (EIT) is a non-invasive, bedside monitoring technique that provides continuous, real-time information about the regional distribution of the ventilation. There are very few data in children admitted to the PICU (pediatric intensive care unit) and the aim of the study is to describe the distribution of the ventilation in children with acute respiratory failure and to study the impact of the interventions in the PICU (change in ventilatory settings, change in position, suction, respiratory kinesiotherapy,…)

Detailed Description
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Children with acute respiratory failure admitted to the PICU (pediatric intensive care unit)

Official Title
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Study on Ventilation Distribution With Electrical Impedance Tomography for Paediatric Respiratory Failure: Impact of Intervention

Conditions
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Acute Respiratory Failure

Intervention / Treatment
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* Procedure: Electrical impedance tomography


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Groupe A children < 18 years Admitted to the PICU with acute respiratory failure Monitoring with EIT non opposition of parents or legal representative Groupe B children < 18 years With general anesthesia and mechanical ventilation Monitoring with EIT non opposition of parents or legal representative Exclusion Criteria: Monitor not available contra indication to the use of thoracic belt Intraoperative period with use of electrocautery Child not affiliated to a social security system and under protective measures legal

Ages Eligible for Study
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Minimum Age: 0 Years
Maximum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Group A<br>group A: Patient < 18 years old admitted to a continuous monitoring unit - resuscitation for acute respiratory failure regardless of the ventilation modality and benefiting from TIE monitoring | Procedure: Electrical impedance tomography<br>* All change in ventilator settings (mode, tidal volume or inspiratory pressure, Peep, recruitment…)<br>|
| Group B (reference)<br>Group B (reference): Patient under general anesthesia with mechanical ventilation without respiratory pathology. | Procedure: Electrical impedance tomography<br>* All change in ventilator settings (mode, tidal volume or inspiratory pressure, Peep, recruitment…)<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Distribution of Ventilation | Distribution of ventilation as determined by changes in impedence in region of interest | up to 48 hours | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Electrical impedance tomography, Children, Pediatric intensive care unit