Outcome of Elderly Patients With Appendicitis

Study Overview
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Brief Summary
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This study aims to evaluate factors that predict 30-day complications after the surgical treatment of appendicitis in elderly patients.

Detailed Description
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Appendicitis in elderly patients is more challenging due to delayed presentation and higher comorbidities, which is associated with increased postoperative morbidity and mortality. In this study, we aim to investigate the factors that predict 30-day complications after the surgical treatment of appendicitis in elderly patients. Records of patients who underwent appendectomy for appendicitis will be extracted. The primary outcome is 30-day postoperative complications. Independent variables examined include demographics, comorbidities, preoperative laboratory values, pathological findings, and surgical features. Both univariate and multivariate regression will be performed to identify factors associated with postoperative complications.

Official Title
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Factors Associated With Postoperative Complications After the Surgical Treatment of Appendicitis in Elderly Patients

Conditions
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Appendicitis Acute

Intervention / Treatment
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* Procedure: Appendectomy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients aged 65 years and older Patients undergoing appendectomy for acute appendicitis (pathologically confirmed) Patients having complete records of clinical data and postoperative follow-up records Exclusion Criteria: Patients younger than 65 years Patients undergoing an appendectomy as part of another major operation or those with appendiceal malignancy Patients who are treated nonoperatively for acute appendicitis

Ages Eligible for Study
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Minimum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients without complications<br>Patients with uneventful recovery | Procedure: Appendectomy<br>* Surgical treatment for appendicitis<br>|
| Patients with complications<br>Patients experiencing complications within 30 days postoperatively | Procedure: Appendectomy<br>* Surgical treatment for appendicitis<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 30-day postoperative complication rate | The primary clinical outcome of interest is 30-day postoperative complications. The Clavien-Dindo classification will be used to grade postoperative outcomes and complications | 30 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| In-hospital mortality rate | In-hospital mortality is defined as death occurring during the hospital stay after the surgical procedure | 30 days | 
| 30-day readmission rate | 30-day readmission is defined as unplanned readmission to the hospital within 30 days of discharge. | 30 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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appendicitis, geriatrics