Pulmonary Rehabilitation for Idiopathic Pulmonary Fibrosis

Study Overview
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Brief Summary
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The purpose of this study is to determine the effects of Pulmonary Rehabilitation (PR) on shortness of breath, exercise capacity, symptom control, mental health, cognitive function, and quality of life in patients with Idiopathic Pulmonary Fibrosis (IPF). Pulmonary rehabilitation has already been shown to benefit patients with other chronic respiratory diseases, such as chronic obstructive pulmonary disease (COPD). We believe that pulmonary rehabilitation will benefit patients with IPF as well.

Detailed Description
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The goals of this project are to assess the effect of PR on a number of important outcomes in patients with IPF. Once enrolled in the study, subjects will complete a battery of questionnaires and tests that assess symptoms, quality of life, cognition, and mental health, and then subjects will complete a six week outpatient PR program (at National Jewish Medical and Research Center or other PR programs). Subjects will complete the same battery of questionnaires and tests immediately after completion of the PR program and again six months later.

Official Title
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Pulmonary Rehabilitation for Idiopathic Pulmonary Fibrosis

Conditions
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Idiopathic Pulmonary Fibrosis

Intervention / Treatment
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* Other: Pulmonary rehabilitation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 40 years or older Diagnosis of IPF according to American Thoracic Society criteria Exclusion criteria: Patients who have completed a PR program within the last two years Patients with unstable medical conditions that would make PR unsafe

Ages Eligible for Study
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Minimum Age: 40 Years
Maximum Age: 90 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 1<br> | Other: Pulmonary rehabilitation<br>* Pulmonary rehabilitation is a multi-disciplinary program that includes exercise training, disease education, psychosocial education (e.g., stress management, coping with chronic illness) and nutrition education.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Exercise capacity |  | 6 weeks and again at 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cognition |  | 6 weeks and again at 6 months | 
| Quality of life |  | 6 weeks and again at 6 months | 
| Fatigue |  | 6 weeks and again at 6 months | 
| Anxiety |  | 6 weeks and again at 6 months | 
| Depression |  | 6 weeks and again at 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Dyspnea, Pulmonary fibrosis, Pulmonary rehabilitation, Quality of life