Contemporary Modalities in Treatment of Heart Failure

Study Overview
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Brief Summary
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The Contemporary Modalities In Treatment of Heart Failure Registry (COMMIT-HF) is an observational study on an all-comer systolic heart failure population hospitalized in a highly specialized cardiovascular center. The aim of the study is to assess the clinical characteristics, treatment modalities and prognosis in this population.

Detailed Description
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The Contemporary Modalities In Treatment of Heart Failure Registry (COMMIT-HF) is a single-center observational study that is underway in the 3rd Chair and Department of Cardiology of Silesian Center for Heart Diseases in Zabrze, Poland. Data collection is patient-based (not event-based). The main objective of the COMMIT-HF Registry is to clarify the overall clinical characteristics of systolic heart failure patients, their demographics and clinical profile, current management, in-hospital outcomes and long-term follow-up, with regard to the administered treatment. The study population is formed by all-comer patients hospitalized in cardiology wards and intensive cardiac care units with a diagnosis of systolic heart failure. For the purpose of this study heart failure is defined as a set of symptoms resulting from myocardial systolic function impairment, confirmed in resting transthoracic echocardiography with left ventricular ejection fraction (LVEF) ≤35%. Patients with acute coronary syndromes are excluded from the analysis. Complete patient demographics; medical history, complete hospitalization data (diagnostic and therapeutic) and in-hospital results are collected in an electronic form by the attending physician. The patients are under constant follow-up for all cause mortality and major adverse events.

Official Title
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Contemporary Modalities in Treatment of Heart Failure

Conditions
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Heart Failure

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: symptom based diagnosis of heart failure echocardiographically confirmed impaired left ventricular ejection fraction ≤35%. Exclusion Criteria: acute coronary syndrome on admission ≥ 18 years old

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of participants with reported deaths from any cause |  | From date of inclusion until the date of death from any cause, assessed up to 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of participants with reported heart-failure related rehospitalization |  | From date of inclusion until the date of first event, assessed up to 1 year | 
| Number of participants with reported myocardial infarction |  | From date of inclusion until the date of first event, assessed up to 1 year | 
| Number of participants with reported cerebrovascular insult |  | From date of inclusion until the date of first event, assessed up to 1 year | 
| Number of participants to undergo mechanical circulatory support implantation |  | From date of inclusion until the date implantation, assessed up to 1 year | 
| Number of participants to undergo orthotopic heart transplantation |  | From date of inclusion until the date transplantation, assessed up to 1 year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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heart failure, prognosis, clinical characteristics