Adaptation in Lower Extremity After 3 Running Days, With a Group Trained by Eccentric Overload

Study Overview
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Brief Summary
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This study evaluates the changes in muscles and tendons in the lower limb after an intervention of fatigue during 3 consecutive days between trained or not healthy subjects. One of the 2 groups received training by eccentric overload previously.

Detailed Description
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Changes in muscle and tendon tissues, due to exercise, could determine in the future the possibility of an injury. Understand the changes in the mechanical tissues is a key tool for prevention. The evaluation of the thickness and area in tendons, the existence of new vessels within the tendon, muscle pennation angle or thermography are tools that have been widely used to detect these changes. Running is one of the activities that can cause more muscle-tendon injuries, specially overuse injuries. However, the eccentric exercise suggest to make some adaptations in different tissues that may be beneficial to prevent damage after exercise.

Official Title
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Differences in Muscle (Vastus Laterals and Gastrocnemius Medialis) and Tendon Adaptation (Patellar and Achilles) in Lower Extremity After 3 Running Days With a Group Trained by Eccentric Overload, Measured by Ultrasound and Thermography

Conditions
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Sports Injuries

Intervention / Treatment
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* Other: Control
* Other: Eccentric Overload


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Healthy subjects that performs any sport usually Subjects that never have made eccentric training will be included. Subjects must be willing to perform the procedure Sign informed consent Exclusion Criteria: Subjects enrolled with lower limb pathology in last 6 months Subjects that don´t complete all the procedure will be excluded.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Screening
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Eccentric<br>6 Weeks Training with eccentric Overload (Squat with Yoyo Technology) 3 Consecutive Days Running 1 hour at 80% of Maximus Heart Rate | Other: Control<br>* 3 Consecutive Days Running at 80% Maximus Heart Rate<br>Other: Eccentric Overload<br>* Training with Eccentric Overload (Squat in Yoyo Technology) during 6 Weeks 3 Consecutive Days Running at 80% Maximus Heart Rate<br>|
| Active Comparator: Control<br>3 Consecutive Days Running 1 hour at 80% of Maximus Heart Rate | Other: Control<br>* 3 Consecutive Days Running at 80% Maximus Heart Rate<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Composite Measure with Ultrasound in Tendons and Muscles | Ultrasound in Patellar and Achilles Tendon, to measure area, thickness and new blood vessels with Doppler. Ultrasound in Vastus Lateralis and Gastrocnemius Medialis to measure pennation angle | Change from Baseline in tendon structure, an expected average of 3 days of running | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Temperature changes in Patellar and Achilles Tendon as assessed by thermography | Thermography in Patellar and Achilles Tendon in order to measure changes in temperature os these areas of interest | Change from Baseline in tendon structure after 3 days of running. Just immediately and 10 minutes after intervention | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Tendon, Eccentric, Running, Muscle, Ultrasound, Thermography