Optimization of Drug Treatment in Hospitalized Elderly (OMAGE)

Study Overview
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Brief Summary
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A randomized trial has been designed to determine if this complex intervention can significantly decrease the risk of unplanned readmissions in this very elderly population, compared with usual care.

Detailed Description
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Drug treatment in elderly is not yet optimal. 20 to 30% of admissions of elderly aged over 80 are related to drug problems, most of them being preventable. To decrease drug related hospitalizations need iatrogenic prevention, compliance improvement, and underuse decrease. A multifaceted intervention has been designed, included three dimensions : 1/ drug optimization 2/ patient and/or caregiver education and 3/ better coordination with home health professionals before discharge. A randomized trial has been designed to determine if this complex intervention can significantly decrease the risk of unplanned readmissions in this very elderly population, compared with usual care.

Official Title
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Impact of Optimization of Drug Treatment of Elderly Admitted in 4 Acute Geriatric Wards : Randomized Trial

Conditions
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Global Medical Assessment of Elderly Frail Patients

Intervention / Treatment
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* Procedure: drug - oriented multifaceted intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients hospitalized as a matter of urgency in unity(unit) of geriatrics acute Patients of more than 70 years old Hospitalization in the Unity(Unit) of Geriatrics foreseen(planned) superior acute in 5 days enlightened assent writing and signed preliminary medical examination Exclusion Criteria: Patients in scheduled(programmed) hospitalization Patient in palliative care Patient whose vital forecast is engaged(opened) in 3 months Patient already include during a previous hospitalization Patient already included in a study concerning the therapeutic care Followed medical impossible (refusal of care, absence of alive regular, patient doctor abroad) not membership to a regime of Social Security or CMU Patient not speaking French

Ages Eligible for Study
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Minimum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 1<br> | Procedure: drug - oriented multifaceted intervention<br>* oriented multifaceted intervention<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rate of unplanned readmissions, including emergency consultations, |  | during the study | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mortality at 6 months, |  | at 6 months | 
| delay before readmission, |  | before readmission | 
| number of drug events related readmissions. |  | readmissions | 
| Data collected at 3 and 6 months |  | at 3 and 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Frail Elderly, Patient Education, Drug optimization, Underuse, Vulnerable, Drug related hospitalization, Medical intervention