Laparoscopic Colectomies In Management of Colonic Cancers

Study Overview
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Brief Summary
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The aim of this study is to compare the Surgical outcomes after laparoscopic intracorporeal versus extracorporeal anastomosis for right and left hemicolectomies in management of colonic cancers .

Detailed Description
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This is clinical trial ,Interventional quasi experiment study to evaluate the surgical outcomes between intracorporeal versus extracorporeal anastomosis in laparoscopic right and left hemicolectomies including post operative pain, hospital stay, leakage from anastomosis, early recurrence, hernias patient satisfaction operative time and more surgical outcomes. In Egyptian hospitals. Source of data the investigators follow up and medical reports and more . surgical procedures This trial including two groups of patients with right and left cancer colon undergoing Laparoscopic colectomy. First group (A) will be operated as intracorporeal anastomosis while the second group (B) will be operated as extracorporeal anastomosis. Sample size more than 50 person Statistical analysis plan Statistical Package for the Social Sciences (SPSS) program

Official Title
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Surgical Outcomes After Laparoscopic Intracorporeal Versus Extracorporeal Anastomosis for Right and Left Hemicolectomies In Management of Colonic Cancers

Conditions
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Laparoscopic Colectomy, Cancer Colon, Intracorporeal Anastomosis

Intervention / Treatment
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* Procedure: laparoscopic intracorporeal versus extracorporeal anastomosis for right and left hemicolectomies


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients had to present histologically confirmed cancer( right and left) colon. All grades of cancer will be included. Cancer at cecum ,appendix, ascending colon, hepatic flexure or at splenic flexure , descending colon and sigmoid colon. Exclusion Criteria: Locally advanced disease with invasion of adjacent important organs. Acute bowel obstruction or perforation from cancer. Pregnant ladies. Rectal cancer and transverse colon cancer.

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 90 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: right and left hemicolectomies in colonic cancers
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: laparoscopic intracorporeal anastomosis for right and left hemicolectomies<br>Surgical outcomes after laparoscopic intracorporeal versus for right and left hemicolectomies in management of colonic cancers | Procedure: laparoscopic intracorporeal versus extracorporeal anastomosis for right and left hemicolectomies<br>* laparoscopic intracorporeal versus extracorporeal anastomosis for right and left hemicolectomies in management of colonic cancers<br>|
| Active Comparator: laparoscopic extracorporeal anastomosis for right and left hemicolectomies<br>Surgical outcomes after laparoscopic extracorporeal anastomosis for right and left hemicolectomies in management of colonic cancers | Procedure: laparoscopic intracorporeal versus extracorporeal anastomosis for right and left hemicolectomies<br>* laparoscopic intracorporeal versus extracorporeal anastomosis for right and left hemicolectomies in management of colonic cancers<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| intraoperative time of surgery | intraoperative time of surgery by minutes | intraoperative time of surgery | 
| post operative hospital stay | post operative hospital stay by days | up to 1 year | 
| Post operative leakage | Post operative leakage of anastomosis by follow up ultrasound, Abdominal Xray erect & wound infection | 1 year | 
| early recurrence of the cancer | early recurrence of the cancer by CT scan | 6 months after surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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intracorporeal, extracorporeal, laparoscopic, anastomosis, hemicolectomies, , colonic cance