Effect of Yellow Pea Protein and Fibre Added to a High-carb Meal on Glycemic Response and Food Intake

Study Overview
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Brief Summary
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The investigators hypothesized that consuming isolated yellow pea fibre or protein, alone to together, as part of a high-carbohydrate pasta meal, would reduce the blood glucose response to the meal compared to a meal without yellow pea components and reduce food intake at a meal served 2 hours later.

Conditions
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Obesity, Diabetes

Intervention / Treatment
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* Dietary Supplement: Pasta meal with added fractions or control with no fractions


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Non-smoking No metabolic disease BMI 20 - 25 kg/m^2 male age 20-30 Exclusion Criteria: Intolerance to treatments on appetite-modifying medications restrictive eating smoking over or underweight breakfast-skipping

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 30 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Control<br>Pasta meal with added fractions or control with no fractions Pasta meal with no pea fractions | Dietary Supplement: Pasta meal with added fractions or control with no fractions<br> <br> |
| Experimental: 10 g protein<br>Pasta meal with added fractions or control with no fractions 10 g net yellow pea protein added to pasta meal | Dietary Supplement: Pasta meal with added fractions or control with no fractions<br> <br> |
| Experimental: 7 g yellow pea fibre<br>Pasta meal with added fractions or control with no fractions 7 g net yellow pea fibre added to pasta meal | Dietary Supplement: Pasta meal with added fractions or control with no fractions<br> <br> |
| Experimental: Yellow pea fibre & protein<br>Pasta meal with added fractions or control with no fractions 10 g net yellow pea protein plus 7 g net yellow pea fibre added to pasta meal | Dietary Supplement: Pasta meal with added fractions or control with no fractions<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Ad libitum food intake at second pizza meal | Food intake measured via electronic scale in g, then converted to kcal using the caloric density. | 135 mins after completion of treatment, 20 mins to eat pizza meal. | 
| Blood glucose | Blood glucose measured via hand-held glucometer and finger prick. | between 0 and 215 mins, every 15-30 mins | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Subjective appetite | Measured via Visual Analog Scales (VAS) | 0 to 215 minutes | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Food intake, satiety, glycemia, appetite, blood glucose, yellow peas, fibre, protein, mixed meal