Implant-supported Fixed Dental Prostheses (FDPs) With Cantilever Extension

Study Overview
=================
Brief Summary
-----------------
To report the clinical and radiographic outcomes of implant-supported fixed dental prostheses with full-ceramic cantilever extensions (FDPCs) after a function time ≥ 12 months.

Detailed Description
-----------------
Patients with full ceramic FDPCs in anterior and posterior areas will be clinically and radiographically re-evaluated. Mesial and distal radiographic marginal bone levels (mBLs) from baseline (i.e. delivery of FDPC) to the follow-up examination were calculated and compared between implant surfaces adjacent to and distant from the cantilever extension. Implant survival rate (%), pocket probing depth (PPD), presence/ absence of bleeding on probing (BoP) and presence/absence of mechanical/technical and biological complications were recorded.

Official Title
-----------------
Clinical and Radiographic Outcomes of Implant-supported Full-ceramic Partial Fixed Dental Prostheses With Cantilever Extension: A Proof of Principle Study With a Follow-up of at Least 1 Year

Conditions
-----------------
Dental Implant Failed, Prosthesis Failure, Peri-Implantitis

Intervention / Treatment
-----------------
* Procedure: Implant-supported fixed dental prostheses with cantilever extension


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients aged ≥18 years Written informed consent Patients with systemic health or controlled medical conditions Patients with healthy or treated periodontal conditions Patients enrolled in regular supportive periodontal therapy (SPT) Patients without clinical signs of bruxism and/or oral parafunctions 2 osseointegrated dental implants in the canine or posterior areas of maxilla and mandible following transmucosal placement and healing of 3-6 months Tissue level solid-screw implants with a sand-blasted and acid- etched (SLA) surface with an endosseous diameter of 3.3, 4.1 or 4.8 mm, a length of 8, 10 or 12 mm, a shoulder diameter of 4.8 mm and a supracrestal machined neck with a height of 1.8 or 2.8 mm (Straumann® Dental Implant System, Institut Straumann AG, Basel, Switzerland) Full-ceramic Utilization of prefabricated titanium abutments Cemented (3M™ ESPE Ketac™ Cem, Seefeld, Germany) or screw-retained fixed dental prostheses with a mesial or distal cantilever extension (FDPCs) Cantilever extension corresponding to 1 premolar unit (i.e., 6-7 mm) Absence of occlusal contacts or guidance on the cantilever extension at baseline Opposing dentition consisting of natural teeth or fixed or removable prosthetic restorations Availability of a periapical radiograph at baseline (i.e. FDPC delivery) Availability of PPD measurements (mm) taken at baseline at 4 sites/implant with a graduated Michigan periodontal probe (Deppeler SA, Rolle, Switzerland) Availability of BoP measurements (%) (Lang et al., 1986) taken at baseline at 4 sites/implant with a graduated Michigan periodontal probe (Deppeler SA, Rolle, Switzerland). Exclusion Criteria: Untreated or active periodontal diseases Immediate implant placement (i.e., Type I implant placement according to Hämmerle et al., 2004) FDPCs in the aesthetic zone (i.e., replacement of maxillary or mandibular incisors) FDPCs supported by hollow-screw and hollow-cylinder implants

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 99 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients with oral implants supporting full ceramic fixed dental prostheses<br> | Procedure: Implant-supported fixed dental prostheses with cantilever extension<br>* Healthy patients in need of replacement of missing teeth with dental implants supporting partial fixed dental prostheses with cantilever extensions<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Implant survival rate | Percentage of dental implants present at follow-up visit | 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Peri-implant marginal bone level changes |  | 12 months | 
| Number of technical complications |  | 12 months | 
| Number of mechanical complications |  | 12 months | 
| Number of Biological complications |  | 12 months |