Socket Preservation Using Autogenous Bone Graft Versus MPM

Study Overview
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Brief Summary
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Studying the comparative effectiveness of socket preservation using autogenous bone graft versus MPM for implant insertion.

Detailed Description
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To assess bone quality, stability of implants placed in fresh extraction sockets of mandibular anterior and premorals augmented by MPM (Mineralized Plasmatic Matrix) versus autogenous bone graft (gold standard), at different follow-up periods (0, 3, 6, 9 months).

Official Title
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Dental Implant Placement in Extraction Socket of Mandibular Anterior and Premolar Areas Treated With Mineralized Plasmatic Matrix Versus Autogenous Bone Graft

Conditions
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Bone Graft; Complications

Intervention / Treatment
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* Other: MPM(Mineralized plasmatic matrix).
* Other: Autogenous Bone Graft


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Medically free patients. Patients with mandibular anterior and premolar hopeless teeth indicated for extraction. Evaluated bone height on X.Ray to be (0-4 mm buccal bone dehiscence). Age between 18 and 40 years. Both sexes. Patients physically able to tolerate surgical and restorative procedures. Good oral hygiene. Highly motivated patients. Exclusion criteria: Smokers. Pregnant or lactating females. Presence of any pathosis in the pre-implant site. Presence of Para functional habits. History of oral radiotherapy. History of prolonged steroids use Psychological disorders.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 40 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Mineralized Plasmatic Matrix<br>MPM(Mineralized plasmatic matrix) insertion in extraction sockets for socket preservation for later implant placement and histomorphometric analysis. | Other: MPM(Mineralized plasmatic matrix).<br>* Preparation of sticky bone graft by addition of growth factors obtained from patient's vebous blood.<br>* Other names: Sticky bone graft.;|
| Active Comparator: Autogenous Bone Graft (Gold Standards).<br>Socket preservation using Autogenous bone graft for later implant placement and histomorphometric analysis. | Other: Autogenous Bone Graft<br>* Socket preservation using autogenous bone graft for preservation of bone width and height for future implant insertion.<br>* Other names: Gold Standards;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Patient Satisfaction regarding function, to be measured using patient questionnaire. |  | 3 Months. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Comparative histomorphometric analysis, to be measured using a digital software called (leica QWin 500) and unit of measurements are to be (Pixels). |  | 3 Months. |