Effects of Red Bull® on the Effects of Training and Haemodynamic Parameters

Study Overview
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Brief Summary
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Background: The consumption of Energy Drinks (EDs) can acutely lead to negative side effects, such as raised blood pressure and impaired endothelial function. Nevertheless, they are sold worldwide and are often consumed before physical activity (PA). In contrast to the blood pressure elevating effect of EDs, PA leads to a reduction of blood pressure. The effect of ED consumption on blood pressure response during and after endurance training is currently unresolved. Methods: A total of 23 participants (eleven men, twelve women) were evaluated in the intervention study with a blinded Cross-Over Design. They consumed on two different days either 355 ml Red Bull (RB) or 355 ml Placebo (Pla) in randomised order. The peripheral (PBP) and central blood pressure (CBP) were measured before, during and after a 30-minute aerobic endurance training, by the Schiller BR-102 plus PWA device.

Detailed Description
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Background: The consumption of Energy Drinks (EDs) can acutely lead to negative side effects, such as raised blood pressure and impaired endothelial function. Nevertheless, they are sold worldwide and are often consumed before physical activity (PA). In contrast to the blood pressure elevating effect of EDs, PA leads to a reduction of blood pressure. The effect of ED consumption on blood pressure response during and after endurance training is currently unresolved. Methods: A total of 23 participants (eleven men, twelve women) were evaluated in the intervention study with a blinded Cross-Over Design. They consumed on two different days either 355 ml Red Bull (RB) or 355 ml Placebo (Pla) in randomised order. The peripheral (PBP) and central blood pressure (CBP) were measured before, during and after a 30-minute aerobic endurance training, by the Schiller BR-102 plus PWA device.

Official Title
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Effects of Red Bull® on the Effects of Moderate Endurance Training Measured by Haemodynamic Parameters

Conditions
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Effects of; Food, Allergic

Intervention / Treatment
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* Dietary Supplement: Red Bull


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: No known cardiovascular diseases such as arterial hypertension and diabetes mellitus. No ophthalmological diseases such as glaucoma or macular degeneration. No regular medication No vasodilator abuse for 24 h before the respective intervention (e.g. smoking, use of stimulants, β-blockers). No pregnancy (anamnestic)

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 40 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Red Bull<br>Drinking of 355 ml Red Bull | Dietary Supplement: Red Bull<br>* Drinking of Red Bull before exercise<br>* Other names: Placebo;|
| Placebo Comparator: Placebo<br>Drinking of 355 ml sweetened water | Dietary Supplement: Red Bull<br>* Drinking of Red Bull before exercise<br>* Other names: Placebo;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Effect on blood pressure | Effect on systolic and diastolic blood pressure | 24 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pulse wave velocity | central pulse wave velocity | 24 hours |