Analysis of the Parameters Obtained on Stabilometric Platform in Patients With PD

Study Overview
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Brief Summary
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Objective: To analyze different parameters in patients with Parkinson's Disease (PD) obtained through the use of a stabilometric platform and compare them with those of a control population. To interpret the data in order to find some postural instability indicators that can become useful to build a rehabilitation strategy for balance disorders in PD.

Detailed Description
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Background: Posture and balance are the foundation on wich upright stance and walking are executed. Postural instability is the impairment in balance that compromises the ability to maintain or change posture such as standing and walking. It is considered to be one of the cardinal features of PD. In such patients it is present even at diagnosis and worsens with disease progression. It correlates with falls representing a major source of disability and reduced QoL in PD. In this course, the study of balance is important to identify patients who can benefit from specific rehabilitative treatment. Objective: To analyze different parameters in patients with PD obtained through the use of a stabilometric platform and compare them with those of a control population. To interpret the data in order to find some postural instability indicators that can become useful to build a rehabilitation strategy for balance disorders in PD.

Official Title
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Analysis of the Parameters Obtained on Stabilometric Platform in Patients With Parkinson's Disease: a Basis for a Rehabilitation Perspective

Conditions
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Parkinson's Disease, Disturbance; Balance, Labyrinth, Other Falls

Intervention / Treatment
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* Other: Stabilometric platform


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: PD according to Gelb et al., in Hoehn-Yahr stage 3, with the ability to walk without any assistance, who had fallen in the last year at least 2 times, with mini-mental state examination score ≥26. Healthy volunteers Exclusion Criteria: atypical parkinsonism patients with cerebro-vascular disorders or other neurological conditions including cognitive impairment. patients with relevant comorbidity or vestibular/visual dysfunctions limiting locomotion or balance.

Ages Eligible for Study
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Minimum Age: 58 Years
Maximum Age: 74 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| 30 patients with PD<br>30 patients (12 M, 18 F, mean age 66,8 ± 8,7) with PD in stage 3 of H&Y will undergo training of balance using a stabilometric platform | Other: Stabilometric platform<br>* Stabilometric platform is a device used for assessment and training of balance basing on ground reaction force evaluation in static conditions.<br>|
| 12 healthy volunteers<br>12 healthy volunteers (3 M, 9 F, mean age 66,5 ± 6,0) served as controls will undergo training of balance using a stabilometric platform | Other: Stabilometric platform<br>* Stabilometric platform is a device used for assessment and training of balance basing on ground reaction force evaluation in static conditions.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Trunk sway | With respect to the average centre of gravity the Standard Deviation of trunk sway (total, in Antero-Posterior and in Medio-Lateral direction) were calculated. In this way it was possible to obtain a statokinesigram, that is the layout of a line connecting the successive positions of the center of pressure during the recording, and the area of the ellipse containing 90% of the sampled positions of the center of pressure. These measurements were obtained with open eyes (OE), and while the patient performing a cognitive task (counting). | One week | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| BBS | Berg Balance Scale | One week | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Stabilometric Platform, Postural instability