Effect of Removal of Double Antibiotic Paste on Post Operative Pain

Study Overview
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Brief Summary
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Recruited patients with necrotic pulp after application of double antibiotic paste are assigned to group (XP Endo Finisher file) and group( Passive ultrasonic irrigation) and group (conventional syringe irrigation with side vented needle) to remove intracanal medication and record postoperative pain afterwards.

Detailed Description
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The investigator will recruit patients who are found eligible to the criteria, double antibiotic paste will be inserted inside the canals. After 7 days, patients will be randomly assigned to either removal of intracanal medication using, the XP-Endo Finisher file, passive ultrasonic irrigation (PUI) and conventional syringe irrigation with side vented needle. After the visit, patients will be asked to record post operative pain by Visual Analog Scale)in a given sheet

Official Title
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Influence of Different Methods of Removal of Double Antibiotic Paste as an Intracanal Medication on Post Operative Pain:a Randomized Clinical Trial

Conditions
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Effects of the Elements

Intervention / Treatment
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* Device: double antibiotic paste with XP-endo Finisher file
* Device: double antibiotic paste with Irrisafe Ultrasonic tip
* Device: double antibiotic paste with side vented needle


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Medically free patients. Patient's age between 20-50 years. Both sexes. Necrotic pulp as indicated by thermal or electric pulp testing. No history of previous endodontic treatment of the tooth. Enough crown structure for adequate isolation. Exclusion Criteria: Pregnancy or lactation Medically compromised patients Previous endodontic therapy of the affected tooth. Teeth diagnosed with vital pulp. Teeth with periodontal pocket more than 3mm deep. Teeth with abnormal anatomy or calcified canals. Teeth with caries below the bony level (non-restorable tooth). Immature teeth with open apices.

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: XP-endo Finisher file<br>removal of double antibiotic paste intracanal medication with XP-endo Finisher file | Device: double antibiotic paste with XP-endo Finisher file<br>* XP-endo Finisher files (FKG Dentaire, La Chaux-de-Fonds, Switzerland). file will be used with an endodontic motor X-Smart (Dentsply Sirona, Ballaigues, Switzerland) in removal of double antibiotic paste<br>|
| Experimental: Irrisafe Ultrasonic tip<br>removal of double antibiotic paste intracanal medication with passive ultrasonic irrigation | Device: double antibiotic paste with Irrisafe Ultrasonic tip<br>* passive ultrasonic irrigation (PUI) with an IrriSafe Ultrasonic tips (Acteon,France), which will be driven by an ultrasonic device (Newtron P5, Satelec, Acteongroup, Merignac, France) in removal of double antibiotic paste<br>* Other names: passive ultrasonic irrigation;|
| Active Comparator: side vented needle<br>removal of double antibiotic paste intracanal medication with conventional syringe irrigation | Device: double antibiotic paste with side vented needle<br>* conventional syringe irrigation with side vented needle (prime Dent, India) in removal of double antibiotic paste<br>* Other names: conventional syringe irrigation;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| change in post operative pain (Visual Analogue Scale) | Numerical (0-10) | Intrappointment at 4,24,48,72 and 96 hours |