Preoperative Laboratory Parameters and Scorings Systems on Postoperative Pulmonary Complications in Thoracic Surgery

Study Overview
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Brief Summary
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Postoperative pulmonary complications (PPC) emerge as a major risk that determines the morbidity and mortality of patients after surgery. PPCs affect the length of hospital stay and increase health costs. Because of this reason, it is important to predict PPCs before surgery. There are many studies on scoring systems that can be effective in predicting PPCs. The most frequently used ones are the Assess Respiratory Risk in Surgical Patients in Catalonia (ARISCAT) risk index, the Nutritional Risk Score (NRS), and the American Society of Anesthesiologist (ASA) score. ARISCAT risk index is mostly evaluated in operations performed other than thoracic surgery. Since the thoracic wall, mediastinum or lungs are directly intervened in thoracic surgery operations, the expected PPCs in these patients may be different from those expected in other surgical groups. Therefore, the ARISCAT risk index may be insufficient to evaluate PPCs in thoracic surgery.

Official Title
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Evaluation of the Effects of Preoperative Neutrophil/Lymphocyte Ratio, Albumin Level, and Various Risk Scorings on Postoperative Pulmonary Complications in Thoracic Surgery. Prospective Observational Study

Conditions
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Perioperative/Postoperative Complications

Intervention / Treatment
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* Procedure: Laboratory parameters and Scoring systems


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients who will undergo elective thoracotomy or video assisted thoracic surgery with general anesthesia BMI < 35 kg/m2 Age 18 - 75 years old Expected operative time more than 60 minutes Exclusion Criteria: History of lung surgery Advanced lung-heart disease Having a previous COVID-19 pneumonia

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: Laboratory parameters and Scoring systems|Neutrophil/ Lymphocite ratio, albumin level and scoring systems has been evaluated.|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Distribution of patients who developed one or more postoperative pulmonary complications according to preoperative neutrophil/lymphocyte ratio, albumin value, ARISCAT risk index, nutritional risk score, and ASA physical status. | Effectiveness of the ARISCAT risk scoring index [ Time Frame: postoperative first 30 days ] to investigate the effectiveness of the ARISCAT risk scoring index in predicting the development of PPC in patients undergoing thoracic surgery. Correlation between ASA physical status (1-3) and PPC [ Time Frame: postoperative first 30 days ] Correlation between NRS ( nutritional risk score) score (0-3) and PPC [ Time Frame: postoperative first 30 days ] Correlation between preoperative albumin values (gram / dl) and PPC [ Time Frame: postoperative first 30 days ] Correlation between preoperative neutrophil/lymphocyte ratio and PPC [ Time Frame: postoperative first 30 days ] | Time to preoperative visit and through study completion, an average of three months. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Distribution of patients who developed one or more postoperative pulmonary complications according to age, gender, BMI and preoperative SpO2 level. | Correlation between age (years) and PPC [ Time Frame: postoperative first 30 days Correlation between gender(male or female) and PPC [ Time Frame: postoperative first 30 days ] Correlation between BMI (kg/m^2) and PPC [ Time Frame: postoperative first 30 days ] Correlation between Preoperative Sp02(>96%, 91%-95%, <90%) and PPC [ Time Frame: postoperative first 30 days ] | Time to preoperative visit and up to 30 days. |