The Effectiveness of Walking in Patients With Systemic Lupus Erythematosus

Study Overview
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Brief Summary
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Expected Results: Finding from this evidence-based study ought to clarify the effectiveness of walking intervention for patients with SLE, and provide reference for future nursing strategies to improve disease adaptability.

Detailed Description
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Background and purpose: Walking exercise may be grateful in strengthening the cardiopulmonary function, regulating the joint flexbility, relieving the pain and the disturbance of sleep, all of which can further improve the quality of life among the patients with chronic diseases. Nevertheless, the information regarding the effect of walking exercise amongst systemic lupus erythematosus (SLE) subjects is still obscure. This study aimed to the influence of quality of life and sleep after the implementation of walking exercise among such groups. uses the Psychometric evaluation of the Chinese version of the Pittsburgh Sleep QualityIndex、Systemic Lupus Erythematosus-Specific Quality of Life Questionnaire and Systemic Lupus Disease Activity of Lupus Erythematosus Disease Activity Score and Taiwanese Depression Questionnaire to evaluate the effectiveness of the intervention of walking exercise on Systemic lupus erythematosus. Methods: Through the quasi-experimental study design, the investigators intend to recruit the SLE patients from a hospital in Taiwan between 2021-2022. The main intervention is composed of home walking, which contained walking guidance and telephone consultation. After that, the investigators apply the structured questionnaires and existing data to collect performance indicators, covering the Chinese version of Pittsburgh Sleep QualityIndex, Systemic Lupus Erythematosus-Specific Quality of Life Questionnaire, Systemic Lupus Disease Activity of Lupus Erythematosus Disease Activity Score, and Taiwanese Depression Questionnaire. The effects of walking exercise is determined by The generalized estimation equations(GEE) .

Official Title
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Buddhist Dalin Tzuchi General Hospital

Conditions
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Systemic Lupus Erythematosus

Intervention / Treatment
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* Behavioral: walking
* Other: Routine care


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients with fulfilled the American College of Rheumatology 1997 criteria for SLE Exclusion Criteria: .patients with cardiovascular disease limited motion, such as bed-ridden, femur head necrosis were pregnant, or had a depressive disorder,

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 64 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: The experiment group is composed of home walking, which contained walking guidance and telephone consultation, the control group without any intervention.
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: The Effectiveness of Walking on Sleep ,Depression and Quality of Life on intervention<br>experimental group: intervention home-style walking exercises performed 12 weeks of 30 minutes walking exercise 2-3 times per week assess on at baseline and 12 weeks | Behavioral: walking<br>* walking for 12 weeks at home<br>|
| Experimental: No intervention group reaction<br>control group: no intervention Routine care and follow-up assess on at baseline and 12 weeks | Other: Routine care<br>* Routine care<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| healthy quality of life Questionnaire | The investigators will assess the Lupus Quality of Life(LupusQoL), from 0 (worst HRQOL) to 100 (best HRQOL) | up to half a year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| score system of depression | The investigators will assess Taiwanese Depression Questionnaire (TDQ) The 18-item TDQ had a sensitivity of 0.89 and a specificity of 0.92 at a cutoff score of 19. | up to half a year | 
| quality of sleep | The investigators will assess Chinese version of Pittsburgh Sleep Quality Index (CPSQI) The CPSQI consists of 19 items that are used to generate seven component scores. A global CPSQI score > 5 indicates that patients suffer from sleep disturbance. | up to half a year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Quality of Life, Quality of Sleep, Walking