Surgical Outcome of Dorsolumbar Intradural Extramedullary Spinal Cord Tumors

Study Overview
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Brief Summary
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Primary spinal cord tumors constitute 2-4% of all central nervous system neoplasms; they are classfied as extradural, intradural extramedullary (IDEM: 65%), and intramedullary The most commonly seen IDEM tumors are schwannomas, neurofibromas, and meningiomas. [1] The less frequently encountered IDEM tumors include ependymomas, lipomas, hemangiomas, metastatic deposits, paragangliomas, nerve sheath myxomas, and vascular tumors.[2] Spinal cord tumors can cause different signs and symptoms, especially as tumors grow. The tumors may affect spinal cord or the nerve roots, blood vessels or bones of spine. Signs and symptoms may include: Pain at the site of the tumor due to tumor growth Back pain, often radiating to other parts of body Feeling less sensitive to pain, heat and cold Loss of bowel or bladder function Difficulty walking, muscle weakness . MRI is the investigation of choice,however other investigation such CT or X ray are important to ensure stability of the vertebral column and the optimal management is gross total excision for symptomatic lesions.[3,4] Over the years, there has been no significant change in the clinical symptoms and pathology of IDEM tumors. However, there have been dramatic improvements in the diagnosis and treatment with the advances of radiological and surgical techniques. Despite advances in operative techniques and neuroimaging, the morbidity associated with the resection of IDEM tumors continues to be significant [5,6]. Here, we examined the surgical outcomes of 20 patients with IDEM spinal cord tumors operated in Neurosurgery department at Sohag university Hospital

Official Title
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Surgical Outcome of Dorsolumbar Intradural Extramedullary Spinal Cord Tumors

Conditions
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Spinal Cord Tumor

Intervention / Treatment
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* Procedure: surgical excision


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients with intradural extramedullary lesion in dorsolumber region Exclusion Criteria: previous history of spinal surgery unfit medical patients multiple level affection associated cervical lesion unstable segment

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: spinal cord tumors group<br> | Procedure: surgical excision<br>* posterior midline approach and total excision for spinal cord tumors<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| american spinal injury association scale | grading of impairment for motor and sensory functions grade A for complete sensory and motor loss grade E for normal motor and sensory | 6 months | 
| visual analogue pain scale | pain scale from zero to ten depend on severity of pain, | 6 months |