Studying the Impact of a Medication Use Evaluation by the Community Pharmacist

Study Overview
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Brief Summary
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In this intervention study, 75 Belgian community pharmacies each recruit 12 patients for an intermediate medication review. For each patient, the identified drug-related problems and subsequent interventions are registered using the PharmDisc classification. In a subset of Dutch speaking patients, a pretest-posttest single group design is used to measure the impact of this review on patient related outcomes using questionnaires. The primary outcome is the medication related quality of life, measured via the living with medicines questionnaire. Other patient reported outcomes include adherence, self-management, patient satisfaction, fall incidents and use of emergency healthcare services. Medication records are also collected to objectively measure adherence before and after the intervention.

Official Title
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Studying the Impact of a Medication Use Evaluation by the Community Pharmacist

Conditions
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Aging

Intervention / Treatment
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* Behavioral: Medication review
* Behavioral: Additional data collection: questionnaires


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients should be 70 years or older Use five or more drugs on a regular basis (prescription or non-prescription drugs) Live in the ambulatory setting Obtain his medication from this pharmacy on a regular basis Exclusion Criteria: -

Ages Eligible for Study
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Minimum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Parallel group intervention study. In a subset of 140 patients, a pre-post study design is used.
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Intervention group: Frenchspeaking patients<br>Intervention: Medication review | Behavioral: Medication review<br>* The intervention consists of a medicines use review provided by community pharmacists in Belgium. A medicines use review is a medication review type 2a in which both a patient interview and dispensing data are used as information sources to identify drug-related problems with a specific focus on the medicines use of the patient.<br>* Other names: Intermediate medication review;|
| Experimental: Intervention group: Dutchspeaking patients<br>Intervention: Medication review Intervention: Dutchspeaking patients are also invited to participate to Additional data collection: questionnaires | Behavioral: Medication review<br>* The intervention consists of a medicines use review provided by community pharmacists in Belgium. A medicines use review is a medication review type 2a in which both a patient interview and dispensing data are used as information sources to identify drug-related problems with a specific focus on the medicines use of the patient.<br>* Other names: Intermediate medication review;Behavioral: Additional data collection: questionnaires<br>* Pre-post study design. At three timepoints, data is collected: before the medication review (T-1week) during the review (Tweek 3) after the review (Tweek12) The questionnaire provide data for the outcomes: medication related quality of life, adherence questionnaire, service satisfaction, use of emergency health services, self-management<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Drug-related problems & interventions | Using the validated PharmDisc classification tool | One timeframe: during the medication review | 
| Change in medication related quality of life | using the Living with medicines questionnaire | Three timepoints: Before the review, during review (week 3), after the review (week 12) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in adherence | using dispensing data | 9 months before and after the intervention | 
| Change in adherence | using the PROMAS questionnaire | Two timepoints: Before the review, after the review (week 12) | 
| Change in self-management | using the PAM questionnaire | Two timepoints: Before the review, after the review (week 12) | 
| Change in use of emergency healthcare services & fall incidents | using own questions | Two timepoints: Before the review, after the review (week 12) | 
| Satisfaction with the new service | Using the PSPSQ2 questionnaire | One timepoint: during the review (week 3) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Aging, Drug-related problems, Medication review, Community pharmacist, Medication use