Randomized Controlled and Prospective Trial of a Cohort of People Who Made a Suicide Attempt

Study Overview
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Brief Summary
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The prevention of recurrent suicidal about people who have made a suicide attempt is a major strand in the prevention of suicide. It is estimated that 10-15 % of people who made a suicide attempt die by suicide. Recidivism rate of suicide increases even faster than the subject is close to the index suicide attempt. A one month recurrence rate is 5 %, 12-25 % at one year. Most people who made a suicide attempt receive ambulatory monitoring. On this population, there is a low adherence to care. The main objective of the study is to test the effectiveness of a prevention program of recurrent suicidal acts for people who made a suicide attempt. The secondary objectives of this study are the assessment of adherence to care; the identification of sub - populations benefiting most from this program; the evaluation of the possible generalization level of the program (eligibles persons rate) and its feasibility level.

Detailed Description
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This is a randomized, controlled and prospective trial comparing an experimental group (usual treatment + interventions) to a control group (usual treatment only). All participants are evaluated after one year of monitoring. The search duration is 2 years (one inclusion year and one year of follow-up). It is planned to include 330 patients, 165 patients in each group. The program (experimental group) includes three interventions: A series of three telephone calls ( the second week , one month and three months after discharge from hospital ) A systematic telephone contact with the referring physician A telephone helpline for people who made a suicide attempt and referring physicians.

Official Title
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Effectiveness of Telephone Contact and Professional Coordination for Preventing Recurrent Suicidal Acts

Conditions
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Suicide, Attempted

Intervention / Treatment
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* Other: Usual treatment and Prevention program
* Other: Usual Treatment


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adults ≥ 18 years. Patients admitted to the emergency department for a suicide attempt. Patients referred to outpatient care. Patients who have given their written consent. Exclusion Criteria: Patients not affiliated to social security. Patients do not have the faculties needed to be evaluated (cognitive or delusional disorder). Patients hospitalized for longer than 72 hours. Patients can not be recalled by phone (no phone, homeless, incarcerated) Patients who do not speak French.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Interventional group<br>Usual treatment + prevention program of recurrent suicidal acts | Other: Usual treatment and Prevention program<br>* Prevention program of recurrent suicidal acts includes three interventions: A series of three telephone calls ( the second week , one month and three months after discharge from hospital ) A systematic telephone contact with the referring physician A telephone helpline for people who made a suicide attempt and referring physicians.<br>* Other names: Prevention program;|
| Active Comparator: Control group<br>Usual treatment | Other: Usual Treatment<br>* Usual Treatment<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| suicidal act frequency | The primary endpoint is the occurrence of a suicidal act (occurrence or not). The suicidal act includes suicide and suicide attempt. | 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| suicide attempts frequency | Number of occurrence of suicide attempts. | 12 months | 
| Adherence to health care | Adherence to health care: Defined by: The Initialization of outpatient care proposed by the suicidology's team at the initial interview or during telephone contacts. The number of consultations within 3 months after the first appointment with the referring doctor. | 12 months | 
| Number of eligibles persons | Number of eligibles persons: Number of people (among all people admitted to the emergency department fo a suicide attempt) meeting the criteria of selection. | 12 months | 
| Number of participants responding to telephone calls | Number of participants responding to telephone calls: We consider the failure to call after three unsuccessful telephone calls to three different days. | 12 months | 
| Number of people lost sight of | Number of people lost sight of: A person is considered lost sight if no information can be obtained after contact with the person himself, a third (nearest designated), a doctor (general practitioner and / or psychiatrist) and the nearest emergency department. | 12 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Suicide, Attempted, prevention suicidal act, telephone contact, professional coordination