The Investigation of Mechanical Properties in Obesity.

Study Overview
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Brief Summary
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The study will demonstrate the relation between muscle tone and viscoelastic properties with the body mass index.

Detailed Description
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Obesity is an increasingly important health problem. It can be defined as excessive fat accumulation. Obesity is a low-severity systemic inflammatory condition that predisposes to chronic diseases.Obesity is closely related to adipose tissue, it can have direct or indirect effects on physical activity and musculoskeletal system. The systems working with oscillation techniques, subcutaneous tissue thickness may affect the probe stroke of the device and oscillation in the tissue. In previous studies were investigated mechanical properties, and BMI used as exclusion criteria is over 30 kg/meter square or keeping it at certain intervals (18-28 kg /meter square) but this proof is not demonstrated and still lack.This study is planned to determine the relation of mechanical properties (tone, stiffness and elasticity) obtained by myotonometric assessment with body mass index.

Official Title
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The Affect of Obesity to Muscle Tone and Viscoelastic Properties

Conditions
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Body Fat Disorder, Obesity, Muscular Tone, Viscoelasticity

Intervention / Treatment
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* Diagnostic Test: Myotonometric assessment


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Body mass index (range; 18 - 35 kg/meter square) Exclusion Criteria: Had any systemic or metabolic disease, psychological illness, or drug use, Had any disease that may cause muscle disease or muscle atrophy, musculoskeletal surgery for the last 3 months

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: The people will assigned to groups depend on body mass index. The biceps brachii (BB), biceps femoris (BF) tone, and viscoelastic properties (stiffness and elasticity) will be evaluated bilaterally using the ''MyotonPRO'' device.
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Normal<br>Body mass index must to be in range limits (18.5-24.9 kg/meter square) | Diagnostic Test: Myotonometric assessment<br>* MyotonPro device is vertically placed on the muscle, a probe (3 mm diameter) creates constant pre-excitations (0.18 N) and generates short-term (15 ms), low-force (0.4 N) mechanical stimulations.These stimulations induce damped natural oscillations in the tissue and the device records these oscillations using an accelerometer. Muscle tone, elasticity, and stiffness are calculated separately by the device<br>|
| Experimental: Overweight<br>Body mass index must to be in range limits (25-29.9 kg/meter square) | Diagnostic Test: Myotonometric assessment<br>* MyotonPro device is vertically placed on the muscle, a probe (3 mm diameter) creates constant pre-excitations (0.18 N) and generates short-term (15 ms), low-force (0.4 N) mechanical stimulations.These stimulations induce damped natural oscillations in the tissue and the device records these oscillations using an accelerometer. Muscle tone, elasticity, and stiffness are calculated separately by the device<br>|
| Experimental: Obese<br>Body mass index must to be in range limits (30-34.9 kg/meter square) | Diagnostic Test: Myotonometric assessment<br>* MyotonPro device is vertically placed on the muscle, a probe (3 mm diameter) creates constant pre-excitations (0.18 N) and generates short-term (15 ms), low-force (0.4 N) mechanical stimulations.These stimulations induce damped natural oscillations in the tissue and the device records these oscillations using an accelerometer. Muscle tone, elasticity, and stiffness are calculated separately by the device<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Stiffness obtained from myotonometric assessment | Myoton device stimulations create natural oscillations in the tissue and records these oscillations using an accelerometer. Stiffness (N/m) is calculated by device | Baseline | 
| Tone obtained from myotonometric assessment | Myoton device stimulations create natural oscillations in the tissue and records these oscillations using an accelerometer. Tone (Hz) is calculated by device | Baseline | 
| Elasticity obtained from myotonometric assessment | Myoton device stimulations create natural oscillations in the tissue and records these oscillations using an accelerometer. Elasticity (log) is calculated by device. | Baseline | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Body mass index, Tone, Viscoelasticity, Obesity