Zirconia Vs Titanium Implants in Deficient Ridges

Study Overview
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Brief Summary
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The aim of this study is to evaluate clinically and radiographically soft tissue around single-implant crowns and peri-implant bone resorption respectively by using zirconia implants or titanium implants in horizontally deficient partially edentulous ridges.

Detailed Description
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Experimental: Main treatment group Zirconia implants will be placed in a prosthetically guided position in horizontally deficient ridges in main treatment group. Active Comparator: Control group Titanium implants will be placed in a prosthetically guided position in horizontally deficient ridges in control group.

Official Title
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Zirconia Vs Titanium Implants in Horizontally Deficient Ridges - A Clinical and Radiographic Outcome-Based Study

Conditions
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Alveolar Bone Loss, Periodontitis

Intervention / Treatment
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* Device: Zirconia implant
* Device: Titanium implant


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Based on the classification of alveolar ridge width given by Tolstunov, subjects with partially edentulous (2/3 teeth missing) systemically healthy subjects within the age group of 25-44 years Class III ridges characterized by moderate i.e., 4-6mm of alveolar ridge width will be included. Exclusion Criteria: Medically compromised patients -. Subjects who underwent radiotherapy or chemotherapy and with Habit of smoking, tobacco and alcohol abuse Subjects with active periodontal disease to residual dentition and lack of oral hygiene will be excluded from this study.

Ages Eligible for Study
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Minimum Age: 25 Years
Maximum Age: 44 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Main treatment group<br>Zirconia implants will be placed in a prosthetically guided position in horizontally deficient ridges in main treatment group. | Device: Zirconia implant<br>* Following standard surgical protocol, Zirconia implant will be placed in horizontally deficient ridge.<br>* Other names: Experimental group;|
| Active Comparator: Control group<br>Titanium implants will be placed in a prosthetically guided position in horizontally deficient ridges in control group. | Device: Titanium implant<br>* Following standard surgical protocol, Titanium implant will be placed in horizontally deficient ridge.<br>* Other names: Control group;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluation of the soft tissue around single implant crowns | Pink Esthetic Score (0-2; increasing scores means improvement in clinical outcomes) is used to evaluate the soft tissue around single implant crowns that might change over time at 3 months and 6 months. | Baseline to 6 months | 
| Peri-implant bone resorption | measured in terms of vertical bone levels present mesial and distal to implant which will be measured by comparing CBCT | Baseline to 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Implant survival rate | Implant survival rate before and after prosthetic loading based on Criteria: A) Persistent pain or dysesthesia B) Peri-implant infection with suppuration C) Absence of mobility D) Absence of continuous peri-implant radiolucency, but with peri-implant bone resorption assessed using dichotomous scale. | Baseline to 6 months |