Identifying Risks of COVID-19 Outbreaks in Work Settings and the Implications for Control Measures

Study Overview
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Brief Summary
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Objectives: To identify core and cross-time workplace hazards and worker's exposure prevention profile towards outbreaks in three non-healthcare work settings; to evaluate effectiveness of a theory-based educational programme on improving attitude to vaccination and virus testing in workplace; to longitudinally compare attitude of willingness to vaccination, testing of SARS-CoV-2 and changes of risk profile toward outbreaks among workers. Design: A 5-year study comprising a randomized controlled trial (RCT) and 3 parallel longitudinal studies with baseline and follow-up repeated measurements. Setting: Non-office, mobile and office work settings. Participants: Part I is a RCT, 294 workers will be randomised to an intervention group (a theory-based education programme) and a control group with measurements repeated at 3rd, 6th and 9th month. Part II is a longitudinal quantitative study (i.e., prospective cohort study) involving 1,495 workers recruited at the baseline and followed up for 2 years. Part III is a longitudinal qualitative study involving 26 management and frontline workers. Part IV is a longitudinal workplace hygiene study involving 6 workplaces enrolled at the baseline and followed up to conduct ventilation investigation. Intervention: Theory-based education intervention to build positive attitude of control measures towards SARS-CoV-2 outbreak. Main outcome measure: Workplace hygiene data (airflow, air volume, etc.); willingness to vaccination and virus tests; actual uptake of SARS-CoV-2 antibody testing. Data analyses: Multivariate regression logistic model and thematically analysed will be performed for quantitative and qualitative analysis. Intention-to-treat analysis will be employed for RCT. Expected results: Large dataset of longitudinal measurement of willingness to vaccination/testing and actual uptake will be documented to inform policy. Educational intervention will be developed to mitigate risks of outbreaks in workplace.

Official Title
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Identifying Risks of Outbreaks in Work Settings and the Implications for Control Measures

Conditions
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Intention to Get SARS-CoV-2 Vaccination, Intention to Get SARS-CoV-2 Antibody Test

Intervention / Treatment
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* Behavioral: Theory of planned behaviours (TPB) based intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: currently being employed in Hong Kong Exclusion Criteria: who have history of physician-diagnosed cancer and sever chronic diseases

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Intervention group will receive theory-based educational intervention using the Theory of Planned Behaviours (TPB) PLUS general health information; Control group will receive only general health information.
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Intervention group<br>This arm will receive TPB intervention to build positive attitudes towards COVID-19 related preventive behaviour (e.g., good compliance with infection control measures, encouraging uptake of testing and vaccination), subjective norms (tackling strategies for perceived social pressure from others or normative beliefs), and improve perceived behavioural control towards risks of outbreaks in workplace. | Behavioral: Theory of planned behaviours (TPB) based intervention<br>* Intervention group will receive TPB-based education program to improve workers' attitude toward SARS-CoV-2 and raise their intention to vaccination and virus testing. The intervention will be implemented at the baseline with measurements repeated at the 3rd month, 6th month and 9th month. The standardized mode of intervention includes face-to-face/online seminar (depends on the COVID-19 situation), message via mobile phone, promotion pamphlet, etc.<br>|
| No Intervention: Control group<br>Control group will receive only general health information. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change of intention to get vaccination of SARS-CoV-2 | A questionnaire will be used to evaluate the intention to get vaccination quantitively. This assessment will be repeated in the 3rd, 6th and 9th month. Change will be assessed among these time points. | 3rd, 6th and 9th month | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change of intention to uptake SARS-CoV-2 antibody test | A questionnaire will be used to evaluate the intention to get rapid antibody test quantitively. This assessment will be repeated in the 3rd, 6th and 9th month. Change will be assessed among these time points. | 3rd, 6th and 9th month | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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workplace hazards, exposure prevention, vaccination, SARS-CoV-2, control measures, willingness, attitude, antibody testing