Validation Study of Posturology Platforms for Evaluating Postural Control of Hemiparetic and Neuro-muscular Patients

Study Overview
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Brief Summary
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The instrumental evaluation of standing postural control by posturographic analysis supplements the clinical evaluation and, as such, is recommended by the French National Authority for Health (HAS 2007). The quantitative data obtained after a standardized postural examination appear relevant for the longitudinal follow-up of neuromuscular patients and hemiparetic patients. Neuro muscular (NM) diseases are progressive, these instrumental evaluations can highlight a deterioration or stabilization of postural control possibly not observable with the scores on clinical scales. The K-Force Plates, recently developed appear to be an interesting alternative to the stabilometry platforms currently used. Static and dynamic conditions in upright position are tested. Moreover, posturologic, kinematics data and clinical scores are correlated to increase understanding of strategies during postural control tasks in patients with stroke and in patients with NM disorders.

Detailed Description
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To date, no clinical validation study of these K-Force Plates force platforms has been proposed. The investigator hypothesize that the data obtained by the Plates are comparable to the measurements made by the reference tool, the AMTI platforms during a static and dynamic posturographic examination in MNM, hemiparetic and healthy subjects. The strategies of the patients (stroke and NM) during the dynamic task are also explored with kinematic analysis in correlation with data from force platforms and clinical scores.

Official Title
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Validation Study of Posturology Platforms and Exploratory Study for Evaluating Postural Control of Hemiparetic and Neuro-muscular Patients

Conditions
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Hemiparesis, Neuromuscular Diseases, Charcot-Marie-Tooth Disease

Intervention / Treatment
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* Other: Posturological examination on KPlates and AMTI platforms
* Other: Berg Balance Scale (BBS)


Participation Criteria
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Eligibility Criteria
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Eligible couples must present all the following criteria : Signing of the informed consent form Men and women aged from 18 Single stroke hemiparetic patient, or patient with neuro-muscular disease, or healthy subject free of neurological disorder and other disease Patient able to stand alone at least 30 seconds without technical assistance (multiple repetitions) To be included, patient should not present any of the following criteria : Bilateral brain injury, cerebellar syndrome Other disease or defect that may interfere with the study such as visual, vestibular or other related uncontrolled medical condition Major cognitive impairment that does not allow evaluation Pregnant women, breastfeeding Non affiliated to a social security scheme

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Neuromuscular disease (MNM) subjects (Charcot Marie Tooth disease, CMT)<br> | Other: Posturological examination on KPlates and AMTI platforms<br>* By an unique evaluator<br>Other: Berg Balance Scale (BBS)<br>* Falls and fera of falling, motor and sensory impairments<br>|
| Hemiparetic subjects<br> | Other: Posturological examination on KPlates and AMTI platforms<br>* By an unique evaluator<br>Other: Berg Balance Scale (BBS)<br>* Falls and fera of falling, motor and sensory impairments<br>|
| Healthy subjects<br> | Other: Posturological examination on KPlates and AMTI platforms<br>* By an unique evaluator<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluate the concurrent validity of K-Force Plates (K-Invent) force platforms in comparison with reference platforms (AMTI) for posturological examination in static and dynamic conditions of MNM subjects (CMT), hemiparetic subjects and healthy subjects. | Intraclass correlation coefficient (ICC) of the mean velocity of the pressure center (CP) with the both platforms during the posturological examination. The average of 3 tests carried out will be taken | Day 0 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluate convergent validity with the reference scale for the assessment of equilibrium disorders | Berg's equilibrium rating scale (0-56) ( score at 0: worse outcome) | Day 0 | 
| Compare the posturology and kinematics between stroke and healthy subjects and between NM and healthy subjects | Explore the relations between the posturology, kinematics and clinical parameters in stroke population and in NM population. | Day 0 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Neuromuscular Diseases, Charcot-Marie-Tooth Disease, Hemiparesis