Sensory Feedback for Touch and Proprioception With Prosthetic Limbs

Study Overview
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Brief Summary
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Upper limb amputation is a devastating injury that leaves many thousands of typically young and active individuals in the US to rely on artificial arms and hands to help restore their lost function. The investigators research is focused on helping these individuals to feel where their prosthetic limbs are moving without having to look at them by developing devices and approaches to provide sensory feedback of limb movement through the nerves that once served the missing limb.

Detailed Description
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In the investigators research the investigators seek to understand the organization and (function/operation) of sensory neural systems in order to develop methods for restoring function to injured populations. One of the primary focus areas of the investigators research is working to integrate physiologically relevant sensory feedback with prosthetic limbs. To this end the investigators employ a variety of approaches that interweave disciplines such as electrophysiology, psychophysics, biomedical engineering and cognition. The investigators research team is composed of an interconnected and communicative network of clinicians, engineers, and scientists. This helps us to provide pathways from basic science discoveries that can be used to address clinical needs with transition directly to patient care.

Official Title
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Sensory Feedback Tactor Systems for Implementation of Physiologically Relevant Cutaneous Touch and Proprioception With Prosthetic Limbs

Conditions
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Prosthetic

Intervention / Treatment
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* Device: Tactor array
* Device: Bypass Tactor


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Amputee criteria: Must be over 18 years of age Must be upper extremity amputee who has undergone targeted sensory reinnervation. Able Bodied participants: Must be over 18 years of age

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Upper Extremity Amputee<br>Robust custom tactor to facilitate embodiment and proprioception | Device: Tactor array<br> <br> |
| Able Bodied<br>Bypass tactor | Device: Bypass Tactor<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Embodiment of the Prosthetic limb | Visual loading for fine motor tasks,questionnaires, and residual limb temperature will be assessed after 10 months of in home every day use of a custom robust tactor array for sensory feedback. | Ten months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Investigate the perceptions of limb movement | Test how closely both targeted reinnervation amputees and able bodied study participants are able to interpret limb movement using the kinesthetic perceptual illusion and physiologically relevant kinesthetic feedback. | 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Upper limb Amputee, Targeted Muscle Reinnervation, Prosthetic