BFR Training on a Bike to Augment RC Strength, Leg Strength, and VO2 Peak

Study Overview
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Brief Summary
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This study will investigate if subjects who bike at 40% of heart rate reserve (HRR) with blood flow restriction (BFR) applied to bilateral thighs for 10 minutes (at 80% limb occlusion pressure) will experience greater gains in 10 rep max for dominant lower extremity leg press, greater gains in rotator cuff strength (hand held dynamometer testing for supraspinatus and external rotators) and greater gains in VO2 peak.

Detailed Description
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This study will randomize healthy adult subjects to one of two groups: a BFR biking group that performs 10 min of cycling at 40% heart rate reserve (HRR) with bilateral occlusion applied to the proximal thighs (80% LOP) or to a non-biking BFR group perform 10 min of cycling at 40% HRR. After each cycling session subjects will perform 3x15 of the scaption exercise and 3x15 sidelying external rotation with their dominant upper extremity. They will initially start training the shoulder at 30% of 1RM (estimated from an equation formula) for the first 2 weeks followed by increasing training load by 1lbs each exercise every 2 weeks. The training program will last 6 weeks (3x week for 6 weeks, total of 18 sessions). Pretest and posttests will include: VO2 peak testing on a cycle using Cosmed metabolic cart, hand held dynamometry to measure strength of the supraspinatus and external rotators of the shoulder using traditional manual muscle test positions, and on a separate day 10RM testing on a leg press for the dominant lower extremity.

Official Title
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Can BFR Training on a Bike Augment RC Strength, Leg Strength, and VO2 Peak

Conditions
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Can BFR Cycling Augment Strength and VO2peak

Intervention / Treatment
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* Other: BFR cycling
* Other: Cycling without BFR


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: healthy adults (18 yrs of age and older) - Exclusion Criteria: no current musculoskeletal symptoms/injuries; no prior lower extremity or shoulder/upper extremity surgery (dominant) during the prior year; no contraindications to BFR training -

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: BFR cycling<br>This group will perform cycling with BFR applied bilaterally at 80% LOP for 10 min and cycling at 40% HRR. Next they will perform 3x15 of the scaption and sidelying external rotation exercises. These will initially be performed at 30% 1RM; every 2 weeks load increased by 1lbs. | Other: BFR cycling<br>* Cycling with BFR followed by shoulder exercises<br>|
| Active Comparator: Cycling without BFR<br>This group will perform cycling and the same shoulder exercises using the same training parameters; however, BFR will not be applied. | Other: Cycling without BFR<br>* Cycling without BFR followed by shoulder exercises<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| VO2peak | Pretest/posttest measures of VO2peak performance on the bicycle using Cosmed Metabolic Cart | 6 weeks | 
| Shoulder Strength | Using a Hand Held Dynamometer; shoulder strength will be measured pretest/posttest for teh supraspinatus and the shoulder external rotators (dominant UE) | 6 weeks | 
| 10 RM unilateral leg press for the dominant lower extremity | Test 10 RM strength on the leg press for the dominant LE/ pretest/posttest | 6 weeks |