Clinical Outcomes of Resective Surgical Treatment of Peri-Implantitis With or Without Implantoplasty

Study Overview
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Brief Summary
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The aims of the current study are 1) to assess the therapeutic resolution of the peri-implantitis after resective surgical treatment with or without implantoplasty procedure (no further radiographic bone loss, no erythema of the peri-implant mucosa, PD <6mm), and 2) to evaluate the survival rate of the peri-implantitis treated dental implants.

Detailed Description
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The records of patients who underwent resective surgical treatment for peri-implantitis at the University of Michigan Graduate Periodontics clinic will be examined and analyzed. Patients who meet the inclusion/exclusion criteria will be contacted and invited to participate in the study to measure the following in a single visit: bleeding on probing, edema, redness of the peri-implant mucosa, and peri-implant probing pocket depth. Additionally, patients will be asked to complete a survey during their study visit regarding their implant(s) and previous peri-implantitis.

Official Title
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Clinical Outcomes of Resective Surgical Treatment of Peri-Implantitis With or Without Implantoplasty. A Retrospective Study

Conditions
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Peri-Implantitis

Intervention / Treatment
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* Other: Observation


Participation Criteria
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Eligibility Criteria
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Inclusion criteria: The patient is at least 18 years of age, was initially diagnosed with peri-implantitis at ≥1 implant (peri-implant probing depth (PPD) ≥ 6 mm together with bleeding and/or suppuration on probing (BOP/SoP) and bone loss progression over physiological bone remodeling radiologically assessed or marginal bone loss ≥ 3 mm radiologically assessed in case of absence of baseline radiographs), had received treatment for peri-implantitis at least 1 year ago at the Graduate Clinic of Periodontics at University of Michigan, and documentation from ≥ 1 year of clinical and radiological follow- up is available from U of M patients records. Exclusion criteria: Has received or is currently receiving radiotherapy, are currently pregnant, unsure of their pregnancy status, or are lactating (as reported by the patient), has health condition(s) or takes medication(s) that are known to affect soft tissue or bone (e.g., Phenytoin) Received any kind of bone graft during the treatment of the peri-implantitis

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Peri-implantitis<br>Patients who underwent resective surgical treatment for peri-implantitis at the University of Michigan Graduate Periodontics clinic from January 1, 1990 through July 1, 2018 | Other: Observation<br>* Soft tissue implant measurements<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Therapeutic resolution of the peri-implantitis as measured by radiographic bone loss | The implant has no further radiographic bone loss when compared to previous radiographs. | Up to 30 years after the implant was treated for peri-implantitis | 
| Therapeutic resolution of the peri-implantitis as measured by erythema | The implant has no current erythema of the peri-implant mucosa. | Up to 30 years after the implant was treated for peri-implantitis | 
| Therapeutic resolution of the peri-implantitis as measured by probing depths | The implant has probing depths less than or equal to 5 millimeters. | Up to 30 years after the implant was treated for peri-implantitis | 
| Survival rate of the peri-implantitis treated dental implants | Survival rate will be determined by the duration of implant survival (functioning, non-symptomatic implant after peri-implantitis treatment). | Up to 30 years after the implant was treated for peri-implantitis |