linjc16/ctgov huggingface dataset:
Quality of Cardiopulmonary Resuscitation Pre- and Intra Hospital

Study Overview
=================
Brief Summary
-----------------
The survival after intrahospital cardiac arrest has been reported to 15%. In Norway this varies between 16 and 23%.). Many factors are associated with survival after cardiac arrest, both intra- and prehospital. Recent studies have not included information about individual patient factors and the outcome after cardiopulmonary resuscitation (CPR). In the current hospital, we are able to record patient specific information related to a cardiac arrest/CPR situation, and thereby be able to assess patient-related factors associated with both detection, treatment and outcome of CPR.

Detailed Description
-----------------
Several factors have been associated with survival, e.g. to monitor hands-off time(Odds ratio, OR, for 2.48, 95% KI 1.11-5.56, p=.03), monthly assessment of all cardiac arrest cases (OR 6.9, 95% KI 1.41-33.92), and includin av local coordinator for CPR (OR 2.93, 95% KI 1.08-7.94, p=.03), as well as depth of compressions. Nevertheless, information about cardiac arrests and CPR have not been assessed in relation to patient specific information. In the current hospital, we are able to record the CPR sequence, and see this in relation to other patient- and case- specific information such as initial cardiac rythm, time to first compression, hands-off time, quality of CPR, and factors affecting the treatment and outcome. The hospital has 71 registered defibrillators used in CPR. The current study will both gather retrospective data- not seen in relation to patient specific information, and prospective data related to specific patients.

Official Title
-----------------
Quality of Cardiopulmonary Resuscitation Pre- and Intra Hospital

Conditions
-----------------
Cardiac Death, Cardiac Arrest, Cardiac Arrhythmia, Cardiac Disease

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: cardiac arrest (all reasons) a defibrillator has been used over 18 years cardiopulmonary resuscitation has been conducted Exclusion Criteria: N/A

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mortality | Patient dead or alive | up to 30 days | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Cardiopulmonary resuscitation, Defibrillation, Ventilation, Quality, Mortality, Morbidity
Longitudinal Assessment of Bariatric Surgery

Study Overview
=================
Brief Summary
-----------------
The goal of the LABS-1 study is to assess the short-term safety of bariatric surgery.

Detailed Description
-----------------
The primary objectives of this study are to assess the safety of bariatric surgery by estimating the prevalence of short term adverse outcomes in a multicenter cohort of patients undergoing bariatric surgical procedures and to determine the associations between short term adverse outcomes after bariatric surgery and both clinical/demographic patient characteristics and features of operative/perioperative care Funds are not available to pay for the surgery for patients, only to address research questions.

Official Title
-----------------
Longitudinal Assessment of Bariatric Surgery (LABS-1)

Conditions
-----------------
Morbid Obesity

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: All patients age 18 years or older, eligible and undergoing bariatric surgery performed by a LABS-certified surgeon. Exclusion Criteria: Patients who do not provide informed consent

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
obesity, bariatric surgery, 30-day mortality
Cross-sectional Study to Assess Prevalence and Burden of CKD-associated Pruritus in Haemodialysis Patients

Study Overview
=================
Brief Summary
-----------------
Vifor International Inc. is seeking real-world evidence (RWE) to better understand the epidemiology, patient characteristics, and management of CKD-aP in the real-world clinical setting.

Detailed Description
-----------------
This is a non-interventional, cross-sectional, multicentre, and multinational (European) study. The non-interventional study (NIS) design allows the observation of patients in large haemodialysis (HD) centres reflecting routine clinical practice. All decisions on therapeutic or diagnostic procedures, treatments, management of the disease, or resource utilisation will be at the full discretion of the treating physician without interference by the sponsor or study protocol. All treatment decisions will follow the real-life treatment behaviour. The CENSUS-EU represents a cross-sectional study design of a representative selection of patients undergoing HD at 113 large dialysis centres across 7 countries in Europe. Prot. v.2.0, 9 May 2023

Official Title
-----------------
RELIEF CENSUS-EU: Cross-sectional Study to Assess Prevalence and Burden of CKD-associated Pruritus in Haemodialysis Patients

Conditions
-----------------
Chronic Kidney Disease-associated Pruritus

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Male or female adult patients with CKD (≥18 years) receiving HD for at least 3 months prior to signing informed consent Signed informed consent Able and willing to fill in questionnaires Exclusion Criteria: Patients performing HD at home or both home and centre

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Haemodialysis Patients<br>Only one data collection timepoint per patient is planned. Eligible and consenting patients will be asked to complete several PROs and one questionnaire, and their respective medical charts will be assessed retrospectively | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prevalence of CKD-aP in HD patients | Percentage (%) | A 7-month study timeline | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The prevalence of CKD-aP by severity | none, mild, moderate, and severe | A 7-month study timeline | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
CKD, CKD-AP, CKD associated pruritus
LCD Solution Versus Calcipotriol Cream in the Treatment of Moderate Plaque Psoriasis

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to compare the safety and effectiveness of a new topical LCD solution and a commercially available calcipotriol (Vitamin D) cream in reducing the symptoms of plaque psoriasis and improving the quality of life in adults.

Official Title
-----------------
A Randomized, Single-Blind, Active Control, 18-Week Study to Evaluate the Safety and Efficacy of A New Twice-Daily, Topically Applied LCD Solution vs. Calcipotriol Cream for the Treatment of Adult Subjects With Moderate Plaque Psoriasis

Conditions
-----------------
Chronic Plaque Psoriasis

Intervention / Treatment
-----------------
* Drug: LCD
* Drug: calcipotriol


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 18 years of age or older able and willing to provide written informed consent diagnosed with chronic plaque psoriasis 3% to 15% body surface area involved in good general health Exclusion Criteria: other current treatments for psoriasis renal or liver dysfunction pregnant or nursing

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 1<br>LCD Solution: 2 applications / day | Drug: LCD<br>* 2 applications / day for 12 weeks<br>|
| Active Comparator: 2<br>Calcipotriol cream: 2 applications / day | Drug: calcipotriol<br>* 2 applications / day for 12 weeks<br>* Other names: Dovonex Cream (50 mcg/g 0.005%);|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Difference in percent reduction in Psoriasis Area and Severity Index (PASI) Scores between treatment arms |  | 12 weeks of treatment | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes in PLASI, PEASI, Physician Global Assessment (PGA), Pruritus, and Dermatology Life Quality Index (DLQI) Scores between treatment arms |  | Week 12 and Week 18 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
psoriasis
Gingival Clefts and Orthodontic Movement

Study Overview
=================
Brief Summary
-----------------
Clefts or invaginations of the gingival tissue are a frequent finding during orthodontic space closure after extraction of a tooth. They occur in about 35% of the cases. Increased risk of developing a gingival cleft is given in the mandibular arch. A gingival invagination impairs aesthetics, orthodontic treatment and periodontal health. The aim of this prospective split-mouth designed observer blinded study is to evaluate possible differences between tooth movement in recent or in healed extraction sockets on incidence of gingival clefts. We hypothesize, that similar to the results originated from an animal study immediate movement in extraction sockets reduces incidence of gingival clefts during orthodontic space closure.

Official Title
-----------------
A Prospective Split-mouth Designed Study on the Incidence of Gingival Clefts During Orthodontic Space Closure Into Recent or Healed Extraction Sockets.

Conditions
-----------------
Gingival Clefts, Extraction Socket, Orthodontic Movement

Intervention / Treatment
-----------------
* Other: time point of tooth extraction


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: extraction of both molars or premolars in the upper or lower jaw and orthodontic space closure Exclusion Criteria: periodontal status not allowing orthodontic treatment

Ages Eligible for Study
-----------------
Minimum Age: 10 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: early or late tooth extraction<br> | Other: time point of tooth extraction<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| incidence of gingival clefts |  | up to 6 months |
Pre-anesthetic Evaluation and Cost Reduction

Study Overview
=================
Brief Summary
-----------------
Study conducted in large Brazilian hospital, with the main objective of evaluating the impact of pre-anesthetic in reducing costs related to the preoperative preparation of patients admitted to undergo surgery or diagnostic procedures under anesthesia.

Detailed Description
-----------------
The pre-anesthetic evaluation is essential in the care of surgical patients. Among its benefits stands the reduction of costs related to preoperative preparation. However, most studies evaluating costs was performed in hospitals abroad, whose reality does not always apply to our environment. The aim of this study is to compare the costs of preoperative evaluation performed by the surgeon (conventional tillage), with the cost of preparation performed by the anesthesiologist (pre-anesthetic evaluation). Two hundred patients scheduled for surgical or diagnostic procedures under anesthesia form included in the study. After admission patients were assessed by physician anesthesiologists. In Form 1 (conventional tillage), it was noted tests or specialist consultations made in the preoperative period. In Form 2 (pre-anesthetic evaluation) was noted comorbidities, physical examination and complementary examinations given in accordance with the guidelines adopted by the Anesthesiology Department of the institution. Form data were compared with a data form 2. Besides the costs, we compared the number of tests considered unnecessary and disagreements in the classification of physical status according to the American Society Anesthesiology (ASA).

Official Title
-----------------
Pre-anesthetic Evaluation and Cost Reduction Perioperative

Conditions
-----------------
Surgical Procedures, Anesthesia

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients over the age of one year and admitted for surgery or diagnostic procedures under anesthesia patient did not undergo pre-anesthetic evaluation prior to admission to hospital Exclusion Criteria: Emergency surgery Major surgery with hospitalization on a date prior to the operation

Ages Eligible for Study
-----------------
Minimum Age: 1 Year
Maximum Age: 90 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
preoperative period, preoperative care, anesthesia, program evaluation
Effect of Ginseng on Glycemic Control

Study Overview
=================
Brief Summary
-----------------
Ginseng (American ginseng, Asian ginseng, Korean ginseng etc) is expected to show positive hypoglycemic effects, including improvements in glycated blood proteins[HbA1c], fasting glucose, fasting insulin, and the homeostasis model assessment of insulin resistance [HOMA-IR]).

Detailed Description
-----------------
Ginseng has demonstrated to have significant hypoglycemic effect. Its major pharmacological component is considered to be ginsenosides. Several trials have been undertaken in diabetes some of which have demonstrated advantages in glycemic control in both diabetic as well as non diabetic individuals although clinical consistency of results is lacking.The lack of high quality data in this area to support diabetes recommendations represents an urgent call for stronger evidence. A systematic review and meta-analysis of controlled trials remains the Gold Standard of evidence for recommendations and clinical guidelines development. Therefore, investigators will conduct a systematic review and meta-analyses of controlled trials to assess the effect of ginseng on glycemic control.

Official Title
-----------------
Effect of Ginseng on Glycemic Control: A Systematic Review and Meta-analysis of Controlled Trials to Provide Evidence-based Clinical Recommendations

Conditions
-----------------
Impaired Glucose Tolerance, Diabetes

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Dietary trials in humans Randomized treatment allocation 1 month Suitable control Viable endpoint data Exclusion Criteria: Non-human studies Non-randomized treatment allocation <1 month Lack of a suitable control No viable endpoint data
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Glycated hemoglobin (HbA1c) |  | 1month | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Fasting blood glucose |  | 1month | 
| Fasting plasma insulin |  | 1 month | 
| Homeostasis model assessment of insulin resistance (HOMA-IR) |  | 1 month |
The Third Survey of Prescription Pattern of Psychotropic Drugs in China

Study Overview
=================
Brief Summary
-----------------
The investigators aimed to examine the psychotropic prescription pattern in China.

Official Title
-----------------
The Third Survey on China Psychotropic Prescription for Schizophrenia, Depression and Bipolar Disorder

Conditions
-----------------
Prescription

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: aged 18-65, inpatient or outpatient, Patient must be willing and able to give written informed consent,the patient suffers from schizophrenia or depression or bipolar disorder - Exclusion Criteria:aged<18or aged>65 -

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Beijing region<br>include six hospitals | |
| Guangdong Province<br>include 3 hospitals | |
| Jiangsu province<br>include 3 hospitals | |
| Hebei province<br>include 6 hospitals | |
| Hubei Province<br>include 7 hospitals | |
| Shanxi province<br>include 3 hospitals | |
| Jiangxi province<br>include 3 hospitals | |
| Jilin province<br>include 6 hospitals | |
| Sichuan province<br>include 3 hospitals | |
| Shaanxi province<br>include 3 hospitals | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
prescription, schizophrenia, depression, bipolar disorder
Evaluation of the Physiopathological Phenomena and the Haemodynamic and Cerebral Metabolic Effects From Semi-seated Position to Lying Position in Patients With Brain Trauma

Study Overview
=================
Brief Summary
-----------------
Brain trauma is an important burden in traumatologic intensive care. In these patients the treatment is guided by a cluster of multimodal monitoring parameters. Despite this it is difficult to assess the actual physiopathologic status of the brain. Changing the position of these patients (semi-seated to lying position) causes changes in the hémodynamics brain conditions, so in monitoring parameters . The analysis of these changes can givr us valuable clinically informations.

Detailed Description
-----------------
Severe brain trauma (CGS < 8 ) are included. PIC, PA, PVC, EKG, airway pressure, SjO2 and NIRSS are continuously monitored. The patients are in semi seated (30°) position. Once a day they are in supine (0°) for 30 minutes. We record every parameters before and at the end of this supine period. After time domain and frequency domain signal processing, this parameters are compared to deduct clinical relevant conclusions.

Conditions
-----------------
Traumatic Brain Injury

Intervention / Treatment
-----------------
* Other: Change from semi-seated position to supine


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients with a severe head trauma estimated by the Glasgow Coma Scale and by the Glasgow Outcome Scale age > 18 Exclusion Criteria: Other neurological pathology

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Patients + parents<br>Patients with severe head trauma | Other: Change from semi-seated position to supine<br>* from semi-seated position (30°) to lying position<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| ASSESSMENT OF THE CEREBRAL OXYGENATION |  | UP TO 6 MONTHS |