A Comprehensive Approach to Secondary HIV Prevention and Care Among Positives

Study Overview
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Brief Summary
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The goal of this study is to conduct an HIV prevention intervention to train HIV seropositive drug users to be peer health educators.

Detailed Description
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The primary objective of this funded research is to conduct an HIV prevention intervention to train HIV seropositive drug users to be peer health educators to: (1) recruit their high risk social network members for voluntary HIV counseling and testing (VCT) at the research clinic, (2) promote risk reduction among social network members, and (3) promote engagement in HIV care by encouraging HIV seropositive network members to schedule and keep HIV primary care appointments. There will be four types of participants in the Full Trial: 1) Index, 2) Testing Network 3) Longitudinal Network and 4) HIV positive network participants. This longitudinal study includes baseline, 6-months, and 12-month assessments

Official Title
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A Comprehensive Approach to Secondary HIV Prevention and Care Among Positives

Conditions
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HIV

Intervention / Treatment
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* Behavioral: Prevention & Testing
* Behavioral: Prevention & Testing Control


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Index 18 years old or older documentation of HIV positive status report one of following risk behaviors in past 90 days: sharing injection equipment, use of crack cocaine, or unprotected vaginal or anal sex Testing network 18 or older provided testing coupon provided by an index participant Longitudinal network participant- tested HIV negative at the Lighthouse via redeeming a testing coupon reported interacting with index who gave the coupon at least weekly report one of following risk behaviors in the prior 90 days: sharing injection equipment, use of crack cocaine, or unprotected vaginal or anal sex Positive Networks HIV positive report one of following risk behaviors in the prior 90 days: sharing injection equipment, use of crack cocaine, or unprotected vaginal or anal sex Exclusion Criteria: Index- already enrolled in the study as a Network participant Testing network- already enrolled in the study as a Network participant Longitudinal network- a) already enrolled in the study as a Network participant b) already enrolled in the study as a Index participant Positive network- a) already enrolled in the study as a Network participant b) already enrolled in the study as a Index participant

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Prevention & Testing Control<br>The comparison condition is focused on basic HIV risk reduction , safety and preventing drug overdose. | Behavioral: Prevention & Testing Control<br>* 7 group sessions<br>|
| Experimental: Prevention & Testing Intervention<br>The intervention condition is training on peer outreach skills which includes talking to HIV positive social network members about HIV care, medication adherence and HIV risk reduction. | Behavioral: Prevention & Testing<br>* 6 group sessions, 1 individual session, and 1 dyad session<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| change in HIV medication adherence |  | 6 month | 
| change in frequency in attending HIV medical appointments |  | 6 month | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| change in sharing injection equipment |  | 6 month | 
| change in condom use |  | 6 month | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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HIV, drug use