Pilates Physical Activity in Sickle Cell Disease

Study Overview
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Brief Summary
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Sickle cell anemia (SCA) is a life-threatening hereditary hemoglobinopathy characterized by hemoglobin (Hb) polymerization that affects many people worldwide.Reduced physical capacity is common in people with SCA. Pilates is a form of physical activity that recently used in clinicial practice

Detailed Description
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SCA patients (40 patients) with ages more than 18 years will join randomly the pilates group (20 patients) or control non exercised group (20 patients). Pilates will be trained 30 minutes (before it there will be warm up period and after it there will be cooldown period , each will be 5 minutes). the pilates will be repeated five sessions per the week for 3 months

Official Title
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Quality of Life Response to Pilates Physical Activity in Sickle Cell Disease

Conditions
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Sickle Cell Disease

Intervention / Treatment
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* Behavioral: Pilates training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: sedentary sickle disease patients from both both sexes in medical stable condition Exclusion Criteria: cardiac complaints, pregnant women, patients who smoke or drink alchols

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 55 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Pilates group<br>this pilates group (20 patients) will be trained 30 minutes of pilates (before it there will be warm up period and after it there will be cooldown period , each will be 5 minutes). the pilates will be repeated five sessions per the week for 3 months | Behavioral: Pilates training<br>* the pilates group (20 patients) will be trained 30 minutes of pilates exercise (before it there will be warm up period and after it there will be cooldown period , each will be 5 minutes). the pilates will be repeated five sessions per the week for 3 months<br>|
| No Intervention: control group<br>The patients will not receive training (20 patients) | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pittsburgh Sleep Quality Index | it assess sleep quality | It will be measured after 12 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| six minutes walking distance | it will assess physical capacity | It will be measured after 12 weeks | 
| quadriceps strength | it will assess the muscular strength of dominant quadriceps | It will be measured after 12 weeks | 
| hand grip strength | it will assess the muscular strength of dominant hand grip | It will be measured after 12 weeks | 
| physical component summary of short-form-36 questionnaire | it will assess physical health | It will be measured after 12 weeks | 
| mental component summary of short-form-36 questionnaire | it will assess mental health | It will be measured after 12 weeks | 
| beck depression inventory | it is a questionnaire assessing depression | It will be measured after 12 weeks |