Tajik Migrant Health Education Study

Study Overview
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Brief Summary
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This study will test the efficacy of a peer-education prevention intervention to reduce risky drug, alcohol, and sexual behaviors among male Tajik labor migrants who inject drugs (MWID) while working in Moscow. The peer educator intervention will be compared to a health education control intervention. Each intervention consists of 5 weekly 2-hour small group sessions. Follow-up assessments will be conducted at 3, 6, 9, and 12 months after the intervention. It is hypothesized that, compared to MWID who receive the health education control intervention, those who receive the peer educator intervention will have a greater reduction in the frequency of risk behaviors. Similar effects are expected for network members of intervention participants.

Detailed Description
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The investigators will recruit male Tajik migrants who inject drugs from 12 different sites in Moscow, including bazaars and other work sites. In both study arms, the recruited men (index participants) will be required to recruit two eligible MWID peers for interviews prior to being interviewed themselves. Participants will be randomly assigned to either the peer educator intervention program or the health education intervention program. After peer-recruited network members are enrolled and interviewed, the index participant will participate in the peer educator training or the control group activities. All participants and recruited network members will then be followed and re-interviewed at 3-month intervals for one year to assess changes in risky drug, alcohol, and sexual behaviors due to intervention participation and through diffusion to network members. The investigators will also collect data from voluntary HIV and HCV testing conducted at 6 months (HCV only) and at 12 months (HIV and HCV) post-intervention.

Official Title
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MASLIHAT Intervention for Tajik Male Migrants Who Inject Drugs

Conditions
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Hepatitis C, HIV Infections, Risky Health Behavior, Risk Reduction Behavior

Intervention / Treatment
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* Behavioral: MASLIHAT
* Behavioral: TANSIHAT


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: adult Tajik man injected drugs in past 30 days living and working as migrant laborer in Moscow Exclusion Criteria: does not intend to stay in Moscow for the next 12 months

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: cluster-randomized parallel groups
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: MASLIHAT peer education<br>A peer educator prevention intervention program consisting of five weekly 2-hour small group sessions. | Behavioral: MASLIHAT<br>* peer educator intervention<br>|
| Sham Comparator: TANSIHAT health education<br>A health education program consisting of five weekly 2-hour sessions small group sessions. | Behavioral: TANSIHAT<br>* health education intervention<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| syringe sharing | frequency of injecting with a previously used syringe | 3 months | 
| sex without condom | frequency of vaginal or anal sex without a condom in the past 3 months | 3 months | 
| alcohol use | Number of days drinking alcohol in past month | 30 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| HIV infection | incident HIV infection | 12 months | 
| hepatitis C infection | incident HCV infection | 12 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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injection drug use, migrant workers, risk behavior