linjc16/ctgov huggingface dataset:
Non-invasive Detection of Anastomotic Leakage

Study Overview
=================
Brief Summary
-----------------
Esophagectomy or pancreaticoduodenectomy is the standard surgical approach for patients with malignant tumors of the esophagus or pancreatic head. These procedures are associated with high morbidity rates, which are strongly correlated with the occurrence of anastomotic leakage. Current diagnostic methods, including clinical, biochemical and radiological techniques are frequently inconclusive. Delay in diagnosis leads to delay in treatment, which ratifies the need for development of novel and accurate non-invasive diagnostic tests for detection of anastomotic leakage. Urinary volatile organic compounds reflect the metabolic status of an individual, which is associated with a systemic immunological response. The aim of this study was to determine the diagnostic accuracy of urinary volatile organic compounds to detect anastomotic leakage after esophagectomy or pancreaticoduodenectomy in an early phase.

Official Title
-----------------
Non-invasive Detection of Anastomotic Leakage Following Esophageal and Pancreatic Surgery by Urinary Analysis

Conditions
-----------------
Anastomotic Leak

Intervention / Treatment
-----------------
* Diagnostic Test: Urinary volatile organic compound analysis


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients were aged 18-90 years American Society of Anesthesiologists (ASA) physical status of 3 or lower All participants were capable to understand the study information and signed written informed consent Exclusion Criteria: None

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 90 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Esophageal anastomotic leakage<br> | Diagnostic Test: Urinary volatile organic compound analysis<br> <br> |
| Esophageal uncomplicated controls<br> | Diagnostic Test: Urinary volatile organic compound analysis<br> <br> |
| Pancreatic anastomotic leakage<br> | Diagnostic Test: Urinary volatile organic compound analysis<br> <br> |
| Pancreatic uncomplicated controls<br> | Diagnostic Test: Urinary volatile organic compound analysis<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Anastomotic leakage |  | Postoperatively (30-days) | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Pancreatic cancer, Esophageal cancer, volatile organic compounds, Field asymmetric ion mobility spectrometry
A Pre-Operative Screening Questionnaire (AMS-Q) for Ambulatory Orthopedic Surgery Patients

Study Overview
=================
Brief Summary
-----------------
We are studying whether providing patients undergoing day surgery the opportunity to have their medical history reviewed by an hospital internist before surgery leads to better results after surgery. These doctors are internal medicine specialists who are experienced in assessing patients going to surgery, making sure they are fine-tuned before their operation. We believe this will ensure the safest and best surgical outcomes. The study involves the patient filling out a 3 page questionnaire for review by the internist prior to surgery. Additionally, patients will receive a follow-up phone call one week after surgery asking about the experience at the hospital and a questionnaire in the mail three months later to see if the patient had any medical problems after leaving the hospital.

Conditions
-----------------
Ambulatory Surgery

Intervention / Treatment
-----------------
* Procedure: Pre-surgical screening


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: All patients having ambulatory surgery performed by one of our participating surgeons during the study period. Exclusion Criteria: Patients who speak neither English nor Spanish. Patients who have had any surgery in the previous 6 months.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Design Details

Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: Pre-surgical screening|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
out patient surgery, quality improvement
Reading Subtitles Skills in the Elementary School

Study Overview
=================
Brief Summary
-----------------
Theme: The reading of fixed texts in school are widely known, however it is not known how they read texts furniture and what skills are required for this type of reading. Objective: To evaluate the skills of reading film subtitles in students of 2nd and 4th grade of elementary school of a Public School. Method: Review the level and skills of reading movies subtitles (RMS), through the recounting of a section of film watched, alone, mute and legend, for 60 students (30 2nd grade and 30 of the 4th grade) matched for age and gender.

Detailed Description
-----------------
The purpose of this study was to compare the reading film subtitles skills in students aged 2nd and 4th grade of elementary school (EF) from a public school, and relate the performance of literacy in school with reading film subtitles. Proceedings: The study included 30 students from 2nd and 30 from 4th grade of a public school at Sao Paulo. The participants' ages ranged from 7 years and 8 months to 9 years and 3 months in the 2nd grade, and 9 years and 9 months to 11 years and one month in the 4th grade. The groups were matched for the genre. Inclusion criteria: sign a consent to search, be literate, do not have any sensory changes, and never repeated a grade. Each subject, individually, was rated about the level of literacy and reading through the protocol of school literacy; and about reading film subtitles skills.Each subject recounted what he understood and responded to five inferential questions about the movie.The recount was analyzed and scored on a specific protocol based on Castillo (1999).Students could score in four levels: decoding, literal comprehension, comprehension independent and critical reading.

Official Title
-----------------
Reading Subtitles Skills in the Elementary School

Conditions
-----------------
Reading Comprehension

Intervention / Treatment
-----------------
* Other: Assessment of reading skills


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: sign a consent to search be literate do not have any sensory changes and never repeated a grade

Ages Eligible for Study
-----------------
Minimum Age: 7 Years
Maximum Age: 9 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| 2nd Grade<br>students of 2nd grade | Other: Assessment of reading skills<br> <br> |
| 4th Grade<br>students of 4th Grade | Other: Assessment of reading skills<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
Retrospective Survey of Bone Fracture in Patients With Arimidex 1mg

Study Overview
=================
Brief Summary
-----------------
The retrospective survey is to investigate the incidence of bone fracture in post-menopausal breast cancer patients with Arimidex 1mg, who were previously registered for the clinical experience investigation.

Official Title
-----------------
Retrospective Survey of Bone Fracture in Post-Menopausal Breast Cancer Patients With Arimidex 1 mg as Adjuvant Therapy

Conditions
-----------------
Breast Cancer

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Post-menopausal breast cancer patients treated with Arimidex 1mg at the time of previously conducted clinical experience investigation. Exclusion Criteria: -
Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bone fracture incidence |  | Time since starting Arimidex | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Survival |  | Time since starting Arimidex | 
| Bone density measurement |  | Time since starting Arimidex | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Breast cancer, post-menopausal women, Arimidex, bone fracture
Skin Tone Preferences and Their Influence on Skin Care Behaviors

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to classify participants by actual skin tone and skin tone preference and identify whether an association exists between these skin tone preferences and knowledge of skin care recommendations, attitudes towards healthy skin care, or skin care behaviors.

Detailed Description
-----------------
This study seeks to examine if there is a difference between ideal and actual skin tone among minority populations. In addition, we hope to assess whether various demographic factors as well as disparity between ideal and actual skin tone effect skin protective behaviors (i.e. sun screen use, dermatologist appointments, skin self-exams) or skin destructive behaviors (i.e. outdoor tanning, tanning salon use, use of skin lightening products) in minority populations.

Official Title
-----------------
Skin Tone Preferences and Their Influence on Skin Care Behaviors

Conditions
-----------------
Dermatology/Skin - Other

Intervention / Treatment
-----------------
* Other: Survey


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Subjects age 18 years old or older Self-identified members of a minority (African, Asian, Hispanic/Latino, American Indian, Alaskan native, etc.) population Subjects who are capable of completing an online, English survey Exclusion Criteria: Subjects age 17 years old or younger Subjects not self-identified members of a minority (African, Asian, Hispanic/Latino, American Indian, Alaskan native, etc.) population Subjects who are incapable of completing an online, English survey

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Survey|Participants will complete a survey online|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Frequency of skin tone differences between ideal and actual | The frequency at which research participants indicate ideal skin tone differences versus actual will be assessed in the questionnaire. The unit of measure will be a numerical value, number of participants. | 6 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
skin care, skin tone, tanning, skin tone preference
Assessment of Siemens' GoBrain and DotBrain Software

Study Overview
=================
Brief Summary
-----------------
Our main approach in this research is to collect MR data using both a Routine and Fast brain protocol on the 3 Tesla Siemens Skyra scanner using a 20-Channel Head/Neck Coil to determine if the Fast protocol can collect data in less time without compromising patient care.

Official Title
-----------------
Assessment of Siemens' GoBrain and DotBrain Software

Conditions
-----------------
Headache

Intervention / Treatment
-----------------
* Other: MRI Imaging


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients referred for MRI with History of Headaches Exclusion Criteria: Patient does not meet MRI safety criteria Patient has known Brain Pathology

Ages Eligible for Study
-----------------
Minimum Age: 7 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Headache Patients<br>Patients Referred for MRI with History of Headaches | Other: MRI Imaging<br> <br> |
| Motion prone patients<br>Patients without the ability to remain still for the entire protocol | Other: MRI Imaging<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Assessment of Siemens' GoBrain and DotBrain Software |  | 1 year |
Augmentation of Maxillary Horizontal And Vertical Bone Deficiency Using Mineralized Plasmatic Matrix

Study Overview
=================
Brief Summary
-----------------
A new technique of grafting introduce called Mineralized plasmatic matrix. This technique can be used in grafting in anterior zone giving a good results and bone substitution occur using allograft or xenograft. The bone graft have a good consistency when it mixed with plasma give easy application, strength and stability of the graft. Also plasma rich with CGF (Cellular growth factors).

Detailed Description
-----------------
Patients suffering from anterior maxillary vertical and horizontal bone loss will be treated using a xeno-graft mixed with the same patient plasma that extracted from his own blood during the operation this graft will be stabilized by collagen membrane and surgical tags. Patients will be follow up for 6 months to measure amount of bone loss of the xeno-graft during this period post operative using C.B.C.T

Official Title
-----------------
Augmentation of Maxillary Horizontal And Vertical Bone Deficiency Using Mineralized Plasmatic Matrix

Conditions
-----------------
Alveolar Ridge Abnormality of Maxilla

Intervention / Treatment
-----------------
* Procedure: Augmentation


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age: from 20 to 40 years old no history of previous grafting. no History of previous implant placement Medically Free e.g no debilitating diseases Exclusion Criteria: Smoker patients. Alcoholic patients Pregnant. Drug Abusers. Hypertensive , Diabetic, having Problems or disease in Kidney and/or liver. Thyroid Disease. Problem in Vit.D absorption or in calcitonin hormone secretion. History of blood transfusion or donating blood less than 4 months. Patient under Corticosteroid therapy. Neurologicaly unstable patients. History of radiotherapy or chemo-therapy. Patient undergo Spect C.T Scan less than 4 Months .

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 40 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: augmentation by xenograft<br>xenograft mixed with plasma extracted from blood | Procedure: Augmentation<br>* combination product<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| amount of bone loss | amount of bone loss after xenograft by CBCT | change from baseline at 6 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Mineralized plasmatic matrix, sticky bone, plasma, autogeous fibrin glue
Prognosis and Treatment of COPD in Primary Care-use of Biomarkers

Study Overview
=================
Brief Summary
-----------------
This is an observational study in primary care aiming to validate biomarkers for chronic obstructive pulmonary disease (COPD).

Official Title
-----------------
Prognosis and Treatment of COPD in Primary Care-use of Biomarkers

Conditions
-----------------
Chronic Obstructive Pulmonary Disease (COPD)

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 40 years old or more, diagnosis of COPD in primary care Exclusion Criteria: Major psychiatric illness, inability to visit primary care doctor, inability to understand danish language,

Ages Eligible for Study
-----------------
Minimum Age: 40 Years
Maximum Age: 100 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Hospitalization |  | December 1, 2015 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Chronic obstructive Pulmonary Disease, COPD
Study of Diquafosol Tetrasodium Ophthalmic Solution in Subjects With Dry Eye Disease

Study Overview
=================
Brief Summary
-----------------
The purpose of this trial is to assess the effectiveness and safety of 2% diquafosol tetrasodium ophthalmic solution versus placebo following 6 weeks of treatment in subjects with mild to moderate dry eye disease.

Official Title
-----------------
A Multi-Center, Parallel Group, Double-Masked, Randomized, Placebo-Controlled Study of Multiple Ocular Instillations of Diquafosol Tetrasodium Ophthalmic Solution, 2% in Subjects With Dry Eye Disease

Conditions
-----------------
Dry Eye Disease

Intervention / Treatment
-----------------
* Drug: diquafosol tetrasodium ophthalmic solution, 2%


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: best corrected visual acuity in both eyes of at least +0.7 six-month documented history of dry eye disease as least mild severity in 1 of the 5 dry eye symptoms corneal fluorescein staining of greater than or equal to 3 and less than or equal to 6 (out of 15) Exclusion Criteria: permanent conjunctival goblet cell loss or scarring conditions ongoing contact lens wear current topical ophthalmic medication use

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: diquafosol tetrasodium ophthalmic solution, 2%|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in dry eye testing measures |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in dry eye testing measures and symptoms |  |  |
Prefrontal Cortex and Abstract Thinking

Study Overview
=================
Brief Summary
-----------------
The capacity of concept formation is not well understood, even if a link is supposed with the functioning of the frontal lobes. Our aim is to better understand the cognitive mechanisms underlying this function and to try to correlate the performance with atrophy of the frontal lobe in neurodegenerative diseases involving this region (frontotemporal lobar degeneration and progressive supranuclear palsy).

Official Title
-----------------
Neuropsychological and Anatomical Study of Concept Formation in Frontal Patients

Conditions
-----------------
Abstract Thinking, Concept Formation

Intervention / Treatment
-----------------
* Behavioral: Neuropsychological examination
* Other: MRI


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: informed consent signed MMSE> 20 No contra indication to MRI Exclusion Criteria: MMSE<20

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| PSP (Progressive supranuclear palsy)<br> | Behavioral: Neuropsychological examination<br>* Examination including especially concept formation<br>Other: MRI<br>* MRI performed in T1-weighted three dimensional sequence<br>|
| FTD (Frontotemporal lobar degenerative)<br> | Behavioral: Neuropsychological examination<br>* Examination including especially concept formation<br>Other: MRI<br>* MRI performed in T1-weighted three dimensional sequence<br>|
| Alzheimer's disease<br> | Behavioral: Neuropsychological examination<br>* Examination including especially concept formation<br>Other: MRI<br>* MRI performed in T1-weighted three dimensional sequence<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
prefrontal cortex