Effect of Exercise on Vitamin d in Obese

Study Overview
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Brief Summary
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The aim of the current study was to investigate the effect of exercise-induced lipolysis on vitamin D status in obese children. Two types of exercises that have different effects on lipolysis were used. Lipolysis was assessed via monitoring the level of plasma level of the free fatty acids and glycerol. Vitamin D was assessed through 25 (OH)D plasma levels.

Detailed Description
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vitamin D status was monitored through 25 (OH)D levels, and the lipolysis status via the plasma level of the free fatty acids and glycerol immediately after the exercise. All subjects who participated in the study were under supervision for controlling the fat contents and vitamin D in their food for one week prior to the exercise. the subjects fasted eight hours before the exercise. All the exercises were performed between 9 am and 11 am.

Official Title
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Effect of Exercise-induced Lipolysis on Vitamin D Status in Obese Children

Conditions
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Obesity, Vitamin D Deficiency

Intervention / Treatment
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* Other: Endurance exercise
* Other: Resistance exersises.


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Body mass index percentile equal to or greater than the 95th percentile All did not receive strength or balance training or involvement in competitive sports emphasizing muscular strength. All participants had balance deficiency and mobile flat foot. 25(OH) D was ranged from 10-20ng/ml Exclusion Criteria: Injury to the lower limb required medical care. Deformity of or surgery in the lower limb. Visual impairment, or neuromuscular disorders. Engagement in obesity treatment programs, three months prior to the study. Epileptic fits Thyroid medications Autoimmune disease Take calcium or vitamin d3 supplements, medications for osteoporosis

Ages Eligible for Study
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Minimum Age: 7 Years
Maximum Age: 10 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: 40 obese children who suffered from vitamin d deficiency were randomly assigned into three groups. group I (15 children) received endurance exercises and group II (15 children) received endurance exercises preceded by resistance exercises which have a stronger lipolytic effect. group III (10 children) acted as a control group.
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: endurance exercise<br>This group received endurance exercises only. | Other: Endurance exercise<br>* Treadmill training at moderate intensity.<br>|
| Experimental: resistance exersise plus endurance exersise<br>This group received resistance exercises followed by endurance exercises. | Other: Endurance exercise<br>* Treadmill training at moderate intensity.<br>Other: Resistance exersises.<br>* Resistance exercises using the 10 repetition maximum.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Free fatty acids | Plasma level of the free fatty acids immediatlly after the exercise. | After 60 min of training | 
| Glycerol | Plasma level of glycerol immediatlly after the exercise. | After 60 min of training | 
| Vitamin D | Plasma level of 25 (OH) D immediatlly after the exercise. | After 60 min of training |