Usual Care Intervention Research Evaluating the Impact of a Personalized Pharmaceutical Plan on the Duration of Opioid Treatment in Non-cancerous Pain

Study Overview
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Brief Summary
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Many treatments with WHO grade III opioids are being introduced in the rheumatology department for non-cancerous pain. The duration of this treatment prescribed at discharge is often uncontrolled and sometimes leads to significant addiction. The team at the local pain center recommends an average duration of 28 days for this type of pain. There is a full-time pharmacy intern in the rheumatology department. The aim of this work is to evaluate the impact of a targeted pharmaceutical interview on the duration of the morphine treatment initiated during hospitalization.

Official Title
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Usual Care Intervention Research Evaluating the Impact of a Personalized Pharmaceutical Plan on the Duration of Opioid Treatment in Non-cancerous Pain

Conditions
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Non-cancerous Pain, Opioid Use

Intervention / Treatment
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* Behavioral: Admission conciliation interview
* Behavioral: Discharge conciliation interview
* Behavioral: Targeted pharmaceutical interview


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age ≥ 18 and < 75 years old when entering the rheumatology department Hospitalization in the rheumatology department Patient with acute non-traumatic musculoskeletal disease Patient not taking grade III opioid treatment Patient affiliated to a social security scheme Patient having read and understood the information letter and signed the consent form Patient present on a day which the pharmacy intern is present Exclusion Criteria: Presence of cancer, fibromyalgia, already diagnosed at inclusion Patient does not understand French Patient with Current or past opioid addiction Person deprived of liberty by administrative or judicial decision

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Patient with targeted pharmaceutical interview<br>Specific information about treatment delivered by pharmacist | Behavioral: Admission conciliation interview<br>* Previous treatment conciliation at hospital admission<br>Behavioral: Discharge conciliation interview<br>* Allocated treatment during hospital stay<br>Behavioral: Targeted pharmaceutical interview<br>* Specific information about treatment delivered by pharmacist<br>|
| Other: Patient without targeted pharmaceutical interview<br>No Specific information about treatment delivered by pharmacist | Behavioral: Admission conciliation interview<br>* Previous treatment conciliation at hospital admission<br>Behavioral: Discharge conciliation interview<br>* Allocated treatment during hospital stay<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Total duration of opioid treatment |  | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rate of patients exceeding 28 days of cumulative duration of treatment |  | 6 months | 
| Rate of patients exceeding 90 days of cumulative duration of treatment |  | 6 months |