Analysis of Joint Sounds in the Diagnosis of Knee Disorders

Study Overview
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Brief Summary
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Clinical-noninvasive recording of sounds from the knees through a brief loaded range of motion. Description in phase 1 analytic but descriptive as well in phase 2. No samples other than a sound recording. The device is known microphone attached to the skin of the knee with elastic material. Sound recorded and analyzed on a lap top computer with Adobe software.

Detailed Description
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There is a need for a less expensive and more universally available screening device for the knee, and other joint pathology. The equipment used for ultrasound is much less expensive and cumbersome than that of an x-ray or magnetic resonance imaging. The equipment we will use for the analysis of sound produced by the body itself is an order of magnitude less expensive than ultrasound; such as a laptop computer with currently available software and an inexpensive transducer. Analysis of sound has proved useful in Pulmonology and Cardiology. We believe sound analysis will provide a useful yet inexpensive tool for primary care physicians as well as musculoskeletal specialists. Phase 1: Establish the normal sound patterns emanating from the uninjured knee; we will look for the influence of age, height and weight. Phase 2: To record and analyze the preoperative sound patterns from the knees with pathology, known by MRI and arthroscopy, then compare them with the normal sounds from Phase 1.

Official Title
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Analysis of Joint Sounds in the Diagnosis of Knee Disorders

Conditions
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Arthritis of Knee, Normal Knee, Knee Arthroscopy

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Phase I Healthy Individuals. No neurological problems. No knee complaints. No previous Surgery or Knee injuries. Phase II Patients undergoing knee arthroscopy who have pre-op MRI. The inclusion will be based on age group, 20 years of age, 40 and 60. Exclusion Criteria: Neurologic Disease Previous serious injury (Fracture or dislocation). Previous Ligament reconstruction. Major non-subtitle problems with their knees. (This would create overwhelming noises).

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Analysis of Joint Sounds in the Diagnosis of Knee Disorders | Phase 1: Analysis will be carried out on the recording from apparently normal knees, sounds are amplification, wave form and filtering. Effects of age, height and weight. Phase 2: analysis of sound will br carried out by a researcher blinded to the MRI and arthroscopic pathology, Then, comparison of the abnormal sounds to the pathology found on the MRI and Arthroscopy to look for correlations. | 1 -2 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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MRI, Knee, Healthy, arthroscopy, amplification, sounds, pre-operative, analyzing