Registry for the Improvement of Postoperative OutcomeS in Cardiac and Thoracic surgEry

Study Overview
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Brief Summary
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The registry for the improvement of postoperative outcomes in cardiac and thoracic surgery aims to prospectively collect data in order to test the association between various preoperative and per-operative variables ; and several postoperative outcomes such as mortality, shock, redo surgery, sepsis and extracorporeal life-support.

Detailed Description
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Cardiac and thoracic surgery is plagued by severe morbidity and mortality. Understanding and being able to predict postoperative outcomes may allow to better fit peri-operative care of cardio-thoracic patients. RIPOSTE database aims to prospectively collect baseline characteristics and per-operative information in order to test associations with the incidence of postoperative outcomes. Baseline characteristics include: age, EuroSCORE 2 and its components (age, gender, New York Heart Association (NYHA) functional class, angina symptoms, insulin-dependent diabetes mellitus, extracardiac arteriopathy, chronic pulmonary dysfunction, neurological or musculoskeletal dysfunction severely affecting mobility, previous cardiac surgery, renal function with creatinin clearance, active endocarditis, critical preoperative state, left ventricle ejection fraction, recent myocardial infarction, pulmonary artery systolic pressure, procedure urgency and weight of the procedure (coronary artery bypass graft, valve surgery and/or thoracic aorta)) weight, height, preoperative biology and preoperative echocardiography parameters when measured. Peroperative information include: cardiac bypass duration, type of procedure, implanted device, valve size. Postoperative outcomes include: death, postoperative shock, mediastinitis, length of stay in intensive care unit, overall length of stay, blood transfusion.

Official Title
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Registry for the Improvement of Postoperative OutcomeS in Cardiac and Thoracic surgEry

Conditions
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Heart Diseases, Death, Postoperative Complications, Cardiac Complication

Intervention / Treatment
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* Procedure: Cardiothoracic surgery


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: all patients eligible for cardiac or thoracic surgery Exclusion Criteria: non applicable
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: Cardiothoracic surgery|Cardiac or thoracic procedure|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| In-hospital mortality | death occurring in the same hospital where the operation took place before discharge from the hospital | During follow-up, until discharge from hospital, up to 1 year. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative shock | Use of catecholamines (dobutamine, norepinephrine and/or epinephrine) in order to achieve adequate cardiac output (cardiac index > 2.2 l/min/m2), in the first 24 hours after surgery | In the first 24 hours after surgery | 
| Length of stay in the ICU (days) | length of stay in the intensive care unit after cardiac or thoracic surgery | During follow-up, until discharge from the ICU, up to 1 year. | 
| Total length of stay (days) | length of stay in the hospital, including preoperative period | During follow-up, until discharge from the hospital, up to 1 year. | 
| Mediastinitis | Incidence of mediastinitis in the postoperative period | During follow-up, until discharge from the hospital, up to 1 year. | 
| Redo surgery | Redo surgery after primary surgery | During follow-up, until discharge from the hospital, up to 1 year. | 
| Pneumoniae | Hospital-acquired or Ventilator-acquired pneumonia as defined by Center for Disease Control guidelines | During follow-up, until discharge from the hospital, up to 1 year. | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Cardiac surgery, Thoracic surgery