Musical Biofeedback for Sensorimotor Control Capacity of Hands

Study Overview
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Brief Summary
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In the proposed study, the investigators assumed that music support treatment, a multisensory-based framework for ameliorating brain plasticity, combined with low-amplitude vibration stimulation can prime motor system and change in motor performance for the patient with a peripheral injury or the loss of a limb. The specific aim of this study is to develop a Multisensory Biofeedback with Musical Interface system, with the aim of improving the sensorimotor impairment of patients' hands.The expected outcomes of this research are to clarify the effects of application Multisensory Biofeedback with Musical Interface on motor and hand function for patients with hand injuries.

Official Title
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Multisensory Biofeedback With Musical Interface for Sensorimotor Control Capacity of Hands

Conditions
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Hand Injuries

Intervention / Treatment
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* Other: regular hand therapy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: tendon and bone injury in hand, wrist, and forearm; peripheral nerve injury in upper extremity; replantation; a combination of nerve and tendon or vascular injury; the protective sensation of the hand is absent or impaired Exclusion Criteria: patients with deficits in cognition, perception or language comprehension, as well as severe pain and swelling in the upper limbs

Ages Eligible for Study
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Minimum Age: 20 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Multisensory-based music treatment<br>Using a multisensory-based music treatment synchronizing with vibrotactile stimulation on the finger pulps during the protection phase (week 0-4) for hand injury patients. | Other: regular hand therapy<br>* edema control, scar management, stretching regimen, tendon gliding exercise, blocking exercise, muscle strengthening protocols<br>|
| Active Comparator: Traditional sensory reeducation intervention<br>Using constant and moving tactile stimulation on the finger pulps during the protection phase (week 0-4) for hand injury patients. | Other: regular hand therapy<br>* edema control, scar management, stretching regimen, tendon gliding exercise, blocking exercise, muscle strengthening protocols<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in the result of pinch-holding-up-activity test |  | 8 weeks, 12 weeks and 24 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Chang in the result of two-point discrimination (S2PD) test |  | 4 weeks, 8 weeks, 12 weeks and 24 weeks | 
| Chang in the result of Semmes-Weinstein monofilament (SWM) test |  | 4 weeks, 8 weeks, 12 weeks and 24 weeks | 
| Chang in the result of active range of motion test |  | 4 weeks, 8 weeks, 12 weeks and 24 weeks | 
| Change in the result of Purdue pegboard test |  | 8 weeks, 12 weeks and 24 weeks | 
| Change in the result of Minnesota manual dexterity test |  | 8 weeks, 12 weeks and 24 weeks | 
| Change in the result of Manual ability measurement |  | 4 weeks, 8 weeks, 12 weeks and 24 weeks | 
| Change in the result of Near-Infrared Spectroscopy |  | 4 weeks and 12 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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musical biofeedback, auditory, vibrotactile stimulation