ICU Nutrition Study Bern

Study Overview
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Brief Summary
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Nutritional treatment has become an essential component of the management of critically ill, due to better knowledge about positive impact of nutritional support. Malnutrition among ICU patients is associated with increased morbidity, mortality, length of stay (LOS) and therefore higher costs.Several studies however suggest, that early implementation of nutritional support is associated with improved clinical outcome, shorter LOS, and decreased infection rates. One of the objectives of this study is to determine if an nutrition protocol can improve the delivery of enteral tube feeding in the ICU.

Official Title
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Implementation of an Evidence-based Nutritional Management Protocol in Critically Ill Patients:Does Clinical Outcome Improve?

Conditions
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Critical Illness, Starvation, Enteral Nutrition

Intervention / Treatment
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* Other: Data Collection
* Other: Nutritional management protocol


Participation Criteria
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Eligibility Criteria
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Exclusion Criteria: <18 years of age stay less than 72 hours on ICU die within 72h after admission patients admitted for palliative care

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Observation<br>Observation | Other: Data Collection<br>* Collection of patient data before implementation of a nutritional management protocol<br>|
| Active Comparator: Nutritional management protocol<br>Collection of patient data after implementation of a nutritional management protocol | Other: Nutritional management protocol<br>* Collection of patient data after implementation of a nutritional management protocol<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Energy delivered (%of caloric target) before and after introducing the nutritional management protocol. |  | During ICU stay | 
| Protein delivered (% of caloric target) before and after introducing the nutritional management protocol |  | During ICU stay | 
| Start of enteral feeding after ICU admission |  | During ICU stay | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| ICU mortality |  | During ICU stay | 
| Hospital mortality |  | During hospital stay | 
| length of ICU stay |  | During ICU stay | 
| length of hospital stay |  | During hospital stay | 
| use of antibiotics (days) |  | During ICU stay | 
| rate of accurately defined infections |  | During ICU stay | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Critical care, Intensive care unit, Early enteral nutrition, Nutritional management protocol