Metastatic Breast Carcinoma and Women Sexual Quality of Life

Study Overview
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Brief Summary
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Sexual health is one of the relevant parameters for assesing the quality of life. Improvement sexual and emotional function improves quality of life scores and depression or anxiety in curative phase. The purpose of the study is to assess the quality of sexual life of postmenopausal women with metastatic breast cancer in couples and to establish links with overall quality of life and the quality of the relationship.

Detailed Description
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We use a quantitative methodology to assess quality of female sexual life, quality of life and quality o relationship with validated scientific questionnaires. The sexual and emotional intimacy will be explored by semi structured interview, not mandatory for patients.

Official Title
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Metastatic Breast Carcinoma: Evaluation of Women Sexual Quality of Life

Conditions
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Metastatic Breast Carcinoma

Intervention / Treatment
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* Other: Medical questionnaire


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Women with metastatic breast cancer Age ≥ 50 and < 70 years old Diagnosis of metastatic breast cancer at least 6 months prior to study participation Patient living with a partner Menopausal women (absence of menstruation for 1 year minimum) ECOG performance status ≤ 2 Affiliated to public health system Informed and having expressed her non-opposition Exclusion Criteria: Patient in exclusive palliative care Single or not living in a couple Non-menopausal patient

Ages Eligible for Study
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Minimum Age: 50 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Medical questionnaire|Brief Index of Sexual Functioning for Women questionnaire Quality of life questionnaire (EORTC QLQ-BR23) Partnership questionnaire (partnerschaftsfragebogen; PFB) Short interview about their sexual intimacy|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Quality of sexual life of postmenopausal women with metastatic breast carcinoma living in couples | Quality of sexual life will assessed by BISF-W (Brief index of sexual functioning for women) questionnaire | 1 day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Quality of life | Quality of life will assessed by quality of life breast cancer module questionnaire (QLQ-BR23) (Hinz et al, 2014) | 1 day | 
| Quality of Relationship of the couple | Quality of Relationship of the couple will assessed by partnership questionnaire (PFB). 30 items making up a global scale measuring the Quality of relationship (PFB).Quality of relationship (PFB) score can be obtained with the following equation: PFB = (30 - Quarreling) + Tenderness + Togetherness/communication ( Rossier et al, 2006). | 1 day | 
| Sexual and emotional intimacy | Patients will be interviewed by open-ended questions face to face concerning their Sexual and emotional intimacy. | 1 day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Cancer, Sexuality, Quality of life, Intimacy, BISF-WBrief Index of Sexual Functioning for Women questionnaire, Quality of life questionnaire (EORTC QLQ-BR23):, Partnership questionnaire (partnerschaftsfragebogen; PFB)