Comparison of Amniotic Fluid Index Between Before and After Maternal Position Change in Upright and Left Lateral Decubitus Position

Study Overview
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Brief Summary
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Comparison of amniotic fluid index between before and after maternal position change in Upright and left lateral decubitus maternal position

Detailed Description
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Amniotic fluid has many important roles in fetal development such as the development of the digestive tract and respiratory system. The quantity of amniotic fluid can be measured by ultrasonography, measuring the deepest pocket in 4 quadrants of uterus then summarize as one value known as amniotic fluid index(AFI). The AFI has the normal range between 5-25 cm. The low AFI (< 5 cm) is associated with abnormal fetal heart rate, and the abnormal AFI does affect to the treatment during the antepartum and intrapartum phase. However , there is the study shown that when compared to the single deepest pocket (SDP) , AFI could detect the oligohydramnios more which might led to the unnecessary labor induction or operative delivery without the significant change of perinatal outcome. To increase the accuracy of AFI, we theorize that maternal position change might affect the amniotic fluid position which would increase the visual of the amniotic fluid as well.

Official Title
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Randomized Controlled Trial of Amniotic Fluid Index Compared Between After Upright and Left Lateral Decubitus Maternal Position Change

Conditions
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Pregnancy Related

Intervention / Treatment
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* Diagnostic Test: Amniotic fluid index


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Pregnant women age 20-34 years whose gestational age was confirmed by ultrasonography before 24 weeks of gestation Exclusion Criteria: Pregnant women with multifetal pregnancy Pregnant women who have underlying disease Pregnant women who have the history of premature rupture of amniotic membrane Pregnant women who have amniotic fluid index below 5 cm (oligohydramnios) Pregnant women who have amniotic fluid index more than 25 cm (polyhydramnios) Pregnant women whose her baby has the fetal anomaly

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 34 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Allocation: Randomized
Intervention Model: Factorial Assignment
Interventional Model Description: Factorial 2-by-2 open labeled randomised controlled trial
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Upright maternal position change<br>The participant will be measured by ultrasonograhy for amniotic fluid index in supine position before maternal position change, then she will do the upright position for 5 minute. After 5 minute of upright position , she will lie down in supine position and she will be measured by ultrasonograhy for amniotic fluid index after upright position. | Diagnostic Test: Amniotic fluid index<br>* Ultrasonography of the amniotic fluid level in each 4 quadrants of uterus then summerize as one value to measure the quantity of amniotic fluid index<br>* Other names: AFI;|
| Experimental: Left lateral decubitus maternal position change<br>the participant will be measured by ultrasonograhy for amniotic fluid index in supine position before maternal position change, then she will do the left lateral decubitus position for 5 minutes. After 5 minutes of left lateral decubitus position , she will lie down in supine position and she will be measured by ultrasonograhy for amniotic fluid index after left lateral decubitus position. | Diagnostic Test: Amniotic fluid index<br>* Ultrasonography of the amniotic fluid level in each 4 quadrants of uterus then summerize as one value to measure the quantity of amniotic fluid index<br>* Other names: AFI;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Amniotic fluid index change after maternal position change | Amniotic fluid index before and after maternal position change | 15 minutes | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Amniotic fluid index