Evaluation of the Effect of Corticotomy and Low Level Laser Therapy on Orthodontic Tooth Movement

Study Overview
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Brief Summary
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The aim of the present study was to compare, a standard efficient technique in accelerating OTM as surgical corticotomy as a gold standard versus surgical corticotomy combined with LLLT in an attempt for further acceleration of OTM.

Detailed Description
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The study design was a randomized split mouth design to compare, clinically and radiographically, between the two interventions (Corticotomy and Laser versus Corticotomy only) by assessing the rate of maxillary canine retraction achieved in 4 months. Secondary outcomes were to evaluate 1st maxillary molar anchorage loss, changes in tipping, torque and rotations values of maxillary canine and 1st molar. In addition, the impact of both interventions on root resorption was assessed. The present study was carried on 16 female patients. All patients required maxillary 1st premolar extraction and subsequent maxillary canine retraction.

Official Title
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Evaluation of the Combined Effect of Corticotomy and Low Level Laser Therapy on the Rate of Orthodontic Tooth Movement: Split Mouth Randomized Clinical Trial

Conditions
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Dental Malocclusion

Intervention / Treatment
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* Procedure: Corticotomy and low laser therapy
* Procedure: Corticotomy facilitated Orthodontics


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Post pubertal patients with age more than 17 years. Class I or Class II (Angles' classification) malocclusion cases requiring 1st premolar extraction with moderate anchorage. Exclusion Criteria: Patients having missing permanent canine teeth in maxillary arch. History of trauma or root canal treatment in maxillary canines. History of previous orthodontic treatment. History of hormonal disorder or syndrome.

Ages Eligible for Study
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Minimum Age: 17 Years
Maximum Age: 25 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Corticotomy facilitated orthodontics.<br>Corticotomy is carried out under local anesthesia in right side. | Procedure: Corticotomy and low laser therapy<br>* Corticotomy is carried out under local anesthesia followed by low-intensity laser therapy that is started on the selected experimental side on the same day as placement of the coil spring<br>|
| Experimental: Corticotomy and low level laser therapy<br>Corticotomy is carried out under local anesthesia followed by low-intensity laser therapy that is started on the selected experimental side on the same day as placement of the coil spring | Procedure: Corticotomy facilitated Orthodontics<br>* Corticotomy is carried out under local anesthesia in right side.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rate of canine retraction | Rate of canine retraction using a digital caliper, units of mm, readings extracted from digital models reading each month. | 4 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Root resorption | Root resorption using CBCT in mm after the end of canine retraction period (at the end of 4 months) | after 4 months from start of clinical trial |