linjc16/ctgov huggingface dataset:
Quality of Life in Schizophrenic Patients

Study Overview
=================
Brief Summary
-----------------
This is a non-interventional study evaluating quality of life in schizophrenic patients treated with atypical antipsychotics, in the ambulatory setting. This is a 9-month, observational, multicentric prospective study.

Official Title
-----------------
QUALITY: A Non-interventional Study Evaluating Quality Of Life in Schizophrenic Patients Treated With Atypical Antipsychotics, in the Ambulatory Setting. A 9-month, Observational, Multicentric Prospective Study.

Conditions
-----------------
Schizophrenia

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients diagnosed with Schizophrenia treated with atypical antipsychotics (ambulatory patients).

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change from baseline of QOL assessed by the SWN-K after 9 months of treatment with AAPs. |  | 9 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Schizophrenia, atypical antipsychotic, quality of life, ambulatory setting
Scoring Model for Predicting Outcome in Patients With Cardiogenic Shock

Study Overview
=================
Brief Summary
-----------------
This study aims to develop a predictive model for the outcomes of patients with cardiogenic shock

Detailed Description
-----------------
This retrospective observational study will enroll patients with cardiogenic shock admitted to the cardiac care unit. Patient characteristics, clinical events during hospitalization, and laboratory examination findings will be collected and analyzed to determine factors associated with mortality. A nomogram will be developed accordingly and will undergo both internal and external validation.

Official Title
-----------------
Scoring Model for Predicting Outcome in Patients With Cardiogenic Shock: From Emergency Room to Intensive Care Unit

Conditions
-----------------
Cardiogenic Shock

Intervention / Treatment
-----------------
* Other: no intervention, this is an observational study


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with cardiogenic shock Admitted to the cardiac care unit (CCU) Exclusion Criteria: Non-cardiogenic shock in origin Post open heart surgery

Ages Eligible for Study
-----------------
Minimum Age: 20 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: no intervention, this is an observational study|no intervention, this is an observational study|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mortality | In-hospital mortality | through study completion, an average of 1 year | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
outcome, cardiogenic shock, epidemiography
Determination of New Biomarkers of Septic Arthritis by Surface-Enhanced Laser Desorption/Ionization Time-Of-Flight (SELDI-TOF)

Study Overview
=================
Brief Summary
-----------------
Septic arthritis is a frequent, potentially disabling and/or life-threatening disease. To diagnose a septic arthritis is a complex procedure, first because of numerous differential diagnoses (such as crystal arthritis), second because of poor sensitivity of initial gram staining (for example after untimely antibiotic therapy). This protocol will use SELDI-TOF as a tool to analyse joint fluid of patients with various acute, polymorphonuclear-rich arthritis, as to determine specific and sensitive new biomarkers of a septic origin. Such biomarkers will allow rapid diagnosis of septic arthritis in the first hours of admission.

Official Title
-----------------
Caractérisation de Nouveaux Biomarqueurs de l'Arthrite Septique Par Technique SELDI-TOF

Conditions
-----------------
Acute Arthritis

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: acute arthritis (onset not more than 7 days ago) joint fluid leukocyte count : more than 2000/mm3, more than 50% polymorphonuclear Exclusion Criteria: none (apart from unability to accept inclusion)

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| septic arthritis<br> | |
| crystal arthritis<br> | |
| rheumatismal disease<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
acute arthritis, bacteria, crystal arthritis, proteomic, SELDI-TOF
The Effect of Medication Reminder Technology on Medication Adherence and Hypertension Outcomes

Study Overview
=================
Brief Summary
-----------------
This study to evaluates how a med reminder affects the patient's ability to take medications as prescribed

Official Title
-----------------
The Effect of Medication Reminder Technology on Medication Adherence and Hypertension

Conditions
-----------------
Medication Adherence, Blood Pressure

Intervention / Treatment
-----------------
* Device: Medication reminder


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: poor medication adherence high blood pressure Exclusion Criteria: -

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Health Services Research
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: medication reminder<br>medication reminder | Device: Medication reminder<br>* Medication reminder<br>|
| Placebo Comparator: Placebo<br>Placebo | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| self-reported medication adherence using the Morisky 8-Item Medication Adherence Scale(MMAS-8) tool |  | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| systolic blood pressure in mmHg using a valid automated device |  | 6 months |
Differentiation of Progression From Treatment Effects in High-Grade Gliomas: A Clinical Trial With Multimodality MR Imaging

Study Overview
=================
Brief Summary
-----------------
To evaluate the efficacy of multi-modality magnetic resonance quantitative parameters in evaluating the treatment effects of high-grade gliomas, and to provide new biomarkers for the establishment of new diagnostic criteria for the identification of true and pseudoprogression of high-grade gliomas.

Official Title
-----------------
Differentiation of Progression From Treatment Effects in High-Grade Gliomas: A Prospective Multicenter Clinical Trial With Multimodality MR Imaging

Conditions
-----------------
Glioma

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with high-grade gliomas confirmed by pathology and have not been treated with concurrent chemoradiotherapy; Written informed consent is obtained. Exclusion Criteria: Patients not suitable for enhanced MRI scanning of patients; Patients who have not finished follow-up concurrent chemoradiotherapy or MR scanning.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Ktrans | The volume transfer constant in dynamic contrast-enhanced MR Imaging | baseline | 
| Ktrans | The volume transfer constant in dynamic contrast-enhanced MR Imaging | 3 months | 
| Ktrans | The volume transfer constant in dynamic contrast-enhanced MR Imaging | 10 months |
BASET Scoring: A Novel Simple Biometric Score and Potential Tool for Diagnosis and Grading of Obstructive Sleep Apnea Syndrome (OSAS) Patients

Study Overview
=================
Brief Summary
-----------------
this study aims to assess the validity of BASET scoring as a new potential tool for diagnosis and grading the severity of OSAS patients and as screening of the risk factors of OSAS.

Detailed Description
-----------------
The study will be conducted on one hundred twenty-six patients attending to sleep disorders breathing Unit, Chest Department at Mansoura University Hospital confirmed by polysomnography

Official Title
-----------------
BASET Scoring: A Novel Simple Biometric Score and Potential Tool for Diagnosis and Grading of Obstructive Sleep Apnea Syndrome Patients

Conditions
-----------------
Obstructive Sleep Apnea

Intervention / Treatment
-----------------
* Diagnostic Test: BASET score


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: All adult patients after having full night polysomnography. Exclusion Criteria: Pregnant patients
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: obstructive sleep apnea patients<br>Group I : consist of sixty-three patients having OSA. Group II : consist of sixty-three non-OSA patients. | Diagnostic Test: BASET score<br>* The patients were divided into two groups. Group I (study group): consist of sixty-three patients having OSA. Group II (control group): consist of eighty-one non-OSA patients<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| assess the performance of BASET score for diagnosis of OSAS | assess the performance of BASET score for diagnosis OSAS Region is neither concave nor dark red will take score (0). Region which is dark red but not concave will take score (1). Region which is concave but not dark red will take score (2). Region which is dark red and concave will take score (3). | up to 2 weeks. | 
| grading of the severity of OSAS patients. | grading of the severity of OSAS patients. Region is neither concave nor dark red will take score (0). Region which is dark red but not concave will take score (1). Region which is concave but not dark red will take score (2). Region which is dark red and concave will take score (3). | up to one week |
Lidocaine Spray Plus Oral Celecoxib for Pain Control During Hysterosalpingography

Study Overview
=================
Brief Summary
-----------------
our aims to investigate the effectiveness of10% Lidocaine Spray plus oral celecoxib for Pain Control During Hysterosalpingography

Detailed Description
-----------------
hysterosalpingography can cause pain and discomfort in several ways: Use of the tenaculum to grasp the cervix and straighten the uterus for proper insertion; trans-cervical actions including measuring uterine depth, inserting the cannula; and injection of the dye

Official Title
-----------------
Lidocaine Spray Plus Oral Celecoxib for Pain Control During Hysterosalpingography: a Randomized Controlled Trial

Conditions
-----------------
IUCD Complication

Intervention / Treatment
-----------------
* Drug: celecoxib plus lidocaine
* Drug: Celecoxib
* Drug: lidocaine


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: any patient came for Hysterosalpingography Exclusion Criteria: any patient has contraindication to Hysterosalpingography

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: randomized controlled trial
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Celecoxib plus lidocaine<br>Celecoxib 200 mg (Celebrex® 200, Pﬁzer,USA) administered orally 2 h before the procedure +10% lidocaine spray 4 puffs during the procedure | Drug: celecoxib plus lidocaine<br>* Celecoxib 200 mg (Celebrex® 200, Pﬁzer,USA) administered orally 2 h before the procedure +10% lidocaine spray 4 puffs during the procedure<br>* Other names: experimental;|
| Active Comparator: Celecoxib<br>Celecoxib 200 mg (Celebrex® 200, Pﬁzer,USA) administered orally 2 h before the procedure +Sterile water 4 puffs during the procedure | Drug: Celecoxib<br>* Celecoxib 200 mg (Celebrex® 200, Pﬁzer,USA) administered orally 2 h before the procedure +Sterile water 4 puffs during the procedure<br>* Other names: Active Comparator;|
| Active Comparator: lidocaine<br>placebo to celecoxib administered orally 2 h before the procedure +10% lidocaine spray 4 puffs during the procedure | Drug: lidocaine<br>* placebo to celecoxib administered orally 2 h before the procedure +10% lidocaine spray 4 puffs during the procedure<br>* Other names: Active Comparato;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mean pain score during the procedure | Assessment of pain using visual analog scale 0-10, 0 = minimum and 10 = maximum scores | 10 minuets |
Correlation Between Clinical and Electrophysiological Phenotypes in a Population of Patients With Neuropathy Charcot-Marie-Tooth Disease Type 1A

Study Overview
=================
Brief Summary
-----------------
This exploratory cross-sectional study proposes, firstly, to objectify in a population of Charcot-Marie-Tooth disease type 1A (CMT 1A)if there is a correlation between the recording of electrical parameters and upper limb muscle strength of the thigh and in a second step, to seek a relationship between the measured parameters.

Detailed Description
-----------------
Patients suffering from CMT 1A neuropathy will be invited to go through a series of tests such as: Electromyography Isokinetic test Podiatric assessment Functional evaluations: Hand dexterity, limbs muscles strength Quality of life assessment with questionnaires

Official Title
-----------------
Correlation Between Clinical and Electrophysiological Phenotypes in a Population of Patients With Neuropathy Charcot-Marie-Tooth Disease Type 1A

Conditions
-----------------
Charcot-Marie-Tooth Type 1A Neuropathy

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients older than 18 years Diagnosis of Charcot Marie Tooth disease, type 1A confirmed by molecular biology (duplication 17.p11.2) Listening and written French Agreement after written information, clear and honest about the purpose of the study, the nature of the tests and their possible side effects or bothersome. Strength of the quadriceps superior to 2/5 MMT MRC Exclusion Criteria: Presence of other neurological comorbidity Presence of coronary artery disease unstabilized Peripheral neuropathy of other causes: diabetes, monoclonal gammopathy, malignancy, solid cancer, systemic autoimmune disease (lupus, Sjögren's disease, Wegener sarcoidosis ...), infectious disease (viral hepatitis, HIV ...), drugs known to be responsible for iatrogenic neuropathy. Gait trouble of other origin Patients unable to give their consent. Intellectual deficit that does not allow to comply with tests

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| axonal loss |  | at day 1 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Muscle strength |  | at day 1 | 
| Functional scores |  | at day 1 | 
| Hand testing |  | at day 1 | 
| spatial and temporal parameters of walking |  | at day 1 | 
| Barometric stabilometric podo-static scores |  | at day 1 | 
| Quality of life |  | at day 1 | 
| Fatigue |  | at day 1 | 
| Depression |  | at day 1 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Walking, Charcot-Marie-Tooth disease type 1A neuropathy, Isokinetic, Electromyography
Effect of Cholesterol Level on Postoperative Acute Kidney Injury of Non-cardiac Surgeries

Study Overview
=================
Brief Summary
-----------------
Preoperative serum cholesterol level may influence occurrence of postoperative acute kidney injury of cardiac surgeries. However, the effect of Preoperative serum cholesterol level for non cardiac surgery remains unknown. This study aimed to explore the effect in non-cardiac surgical population.

Official Title
-----------------
Effect of Cholesterol Level on Postoperative Acute Kidney Injury of Non-cardiac Surgeries

Conditions
-----------------
Acute Kidney Injury

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: adults elective non-cardiac surgery Exclusion Criteria: cardiac surgeries kidney surgeries obstetric surgeries local infiltration anesthesia perioperative data missing

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| post-operative acute kidney injury within 30 days in the hospital | It was defined by patient's postoperative serum creatine increase no less than 26.5 μmol/l within 48 hours, or 1.5 times from baseline within the 7 days after surgery or initializing blood dialysis. | 30 days postoperatively in hospital |
Abdominal Pain Management and Point-of-care Ultrasound in the Emergency Department

Study Overview
=================
Brief Summary
-----------------
Background: Abdominal pain is one of the most common reasons for admission to the emergency department (ED). This study aimed to investigate the effect of point-of-care ultrasound (POCUS) performed during the initial evaluation phase of patients who presented to the ED with abdominal pain on diagnostic processes, length of stay (LOS) in ED, and hospitalization and healthcare costs. Methodology: This prospective, randomized, controlled, parallel group study was conducted with patients who presented to the Sakarya Education Research Hospital ED with abdominal pain from October 2019 to March 2020. Patients were divided randomly into two groups: control group where standard diagnostic strategies were applied and the POCUS group where POCUS was performed together with standard diagnostic strategies. All data were analyzed using IBM SPSS 21.

Official Title
-----------------
Abdominal Pain Management and Point-of-care Ultrasound in the Emergency Department: a Randomized, Prospective, Controlled Study

Conditions
-----------------
Abdominal Pain

Intervention / Treatment
-----------------
* Diagnostic Test: point-of-care ultrasound


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: age >18 years Patients who presented to the ED with abdominal pain Nontraumatic patients Exclusion Criteria: permanent mental disability, age <18 years, abdominal trauma within the last 24 hours, pregnancy, morbid obesity, repeated admissions, referral from an external center to the ED, missing patient information.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: a randomized, prospective, controlled study
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: point-of-care ultrasound group<br> | Diagnostic Test: point-of-care ultrasound<br>* point-of-care ultrasound<br>|
| No Intervention: Control group<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| to measure the effect of POCUS on the Length of stay in emergency department |  | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| to measure the effect of POCUS on the average cost of patients, the rate of change in the preliminary diagnosis of the physician, and hospitalization and discharge rate |  | 1 months after discharge or hospitalisation | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Abdominal pain, Cost, Emergency department, Length of stay, point-of-care ultrasound