Evaluation of Inflammation of the Anterior Segment by Laser Flashmeter in Patients Having Undergone Surgery of the Posterior Segment (Vitrectomy or Preindentation) During the First Postoperative Year. (FLAVIC)

Study Overview
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Brief Summary
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Observational study, monocentric, prospective, descriptive and comparative (eye operated vs fellow eye).

Detailed Description
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After surgery by vitrectomy or preindentation, an anti-inflammatory treatment is conventionally prescribed for a duration of 1 month. However, frequently, during the post-operative control at one month, there may be signs of ocular inflammation or symptoms of discomfort justifying the prolongation of post-operative treatment. A 2012 study evaluated post-operative flare follow-up in 22 vitrectomized patients for retinal detachment, and showed a significantly higher flare 3 months after surgery, compared to the other eye and pre-surgery value. In this study, the investigators wish to study postoperative inflammation in patients operated for posterior segment ocular surgery (vitrectomy or preindentation) measured by laser flashmeter on a follow-up of one year.

Official Title
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Evaluation of Inflammation of the Anterior Segment by Laser Flashmeter in Patients Having Undergone Surgery of the Posterior Segment (Vitrectomy or Preindentation) During the First Postoperative Year. (FLAVIC)

Conditions
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Inflammation Eye

Intervention / Treatment
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* Other: Laser Flare Meter


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Major patient, Operation of vitrectomy or preindentation in the ophthalmology department of Rennes University Hospital for one of the following reasons: Retinal detachment, rhegmatogenous or not Combined surgery Membrane peeling Macular hole Optically targeted vitrectomy (Terson's syndrome, intravitreous haemorrhage) Covered by a health insurance system, Having received information on the protocol and not having expressed opposition to participating in the study Exclusion Criteria: Vitrectomy for endophthalmitis or posterior uveitis, Patient with vitreoretinal proliferation (grade B and C), Pregnant or nursing woman, Major patient subject to legal protection (safeguard of justice, guardianship, guardianship), person deprived of liberty.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Laser Flare Meter|Measurement of the inflammation of the operated eye and the fellow eye before the surgery and at each post-surgery visit: D7, M1, M2, M3, M6, M12|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evolution of the flare value | Evolution of the flare value preoperatively and then to D7, M1, M2, M3, M6, M12 of the operated eye | Changes between baseline (preoperatively) and day 7, month 1, month 2, month 3, month 6, and month 12 measures | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Flare values of the fellow eye and the operated eye | Flare value of the fellow eye and the operated eye at each evaluation time | Difference between flare values of the fellow eye and the operated eye at each evaluation time : baseline (preoperatively), day 7, month 1, month 2, month 3, month 6, and month 12 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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vitrectomy, cryoindentation