Factors Influencing the 3-Year Recurrence of Liver Carcinoma After Surgery

Study Overview
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Brief Summary
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Objective: To study the factors that influence the 3- year recurrence of liver carcinoma after surgery To study the related factors affecting recurrence of liver carcinoma after surgery

Detailed Description
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Liver carcinoma including 80% Hepatocellular carcinoma (HCC) and 20% Cholangiocarcinoma (CCA) becomes the leading causes of death in East and South-East Asia. Though hepatectomy is the treatment of choice for early stage cancer, the recurrence has been reported as 30%, 62% and 79% in 1st, 3rd and 5th year respectively. Chulabhorn hospital, a cancer institute established in 2011, has been performing a 3-years retrospective study on the influencing factors and its correlation to liver carcinoma after surgery.

Official Title
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Factors Influencing the 3-Year Recurrence of Liver Carcinoma After Surgery

Conditions
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Liver Cancer, Recurrence

Intervention / Treatment
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* Other: Recurrence Rate of HCC after surgery
* Other: Recurrence Rate of CCA after surgery


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All patients underwent liver resection for Hepatiocellular carcinoma and Cholangiocarcinoma respectively including having pathology results between February 2010 to December 2013. Data was received from Cholabhron Hospital's patient database. Exclusion Criteria: All patients having no pathology results were not included. All patients having no show for follow up recording were excluded.
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| recurrence rate of HCC after surgery<br>There were 33 for Hepatocellular carcinoma between February 2010 to December 2013. All patients were staged according to the tumor-node metastasis (TNM) system and appraised by the hospital tumor board conference. After surgery, an attending physician followed up patients by tumor marker and imaging as standard treatment as well as diagnosed its recurrence. In addition, all recurrence cases had standard treatments till the end of life. The survival was classified as the dates between the operation and the death. | Other: Recurrence Rate of HCC after surgery<br>* Recurrence Rate of HCC after surgery<br>|
| recurrence rate of CCA after surgery<br>There were 34 patients underwent liver resection for Cholangiocarcinoma between February 2010 to December 2013. All patients were staged according to the tumor-node metastasis (TNM) system and appraised by the hospital tumor board conference. After surgery, an attending physician followed up patients by tumor marker and imaging as standard treatment as well as diagnosed its recurrence. In addition, all recurrence cases had standard treatments till the end of life. The survival was classified as the dates between the operation and the death. | Other: Recurrence Rate of CCA after surgery<br>* Recurrence Rate of CCA after surgery<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Recurrence rate of Liver Carcinoma after surgery |  | 3 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Hepatocellular carcinoma, Cholangiocarcinoma, Recurrence