Improving Evidence-Based Care for Cancer Patients

Study Overview
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Brief Summary
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The purpose of this study is to improve cancer care and the delivery of cancer care. Researchers are interested in studying patient reported information and examining how different factors may impact cancer care.

Official Title
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Improving Evidence-Based Care for Cancer Patients

Conditions
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Head and Neck Cancer, Prostate Cancer, Breast Cancer, Lung Cancer, Gynecologic Cancer, Gastrointestinal Cancer

Intervention / Treatment
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* Other: Survey
* Other: Saliva sample
* Other: Smoking Status questions


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Diagnosed with head/neck, lung, breast, prostate, gastrointestinal or gynecologic cancer 21 years of age or older at time of study registration Must have been referred to MUSC radiation oncology for treatment with curative radiation therapy Must report current smoking defined as self-reporting smoking within the past 30 days using a structured intake questionnaire. Exclusion Criteria: Patients with primary central nervous system malignancies will be excluded. Patients that have other cancer disease types will be excluded due to either significant differences in standard radiation therapy approaches or rarity of disease required radiation. Patients who are currently participating in the Medical University of South Carolina Hollings Cancer Center smoking cessation program Patients who are unable to provide informed consent

Ages Eligible for Study
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Minimum Age: 21 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Arm 1<br>Current smokers with cancer who are planning to get radiation therapy at MUSC. | Other: Survey<br>* Subjects will be asked to complete a survey asking questions about his/her current health, well-being and quality of life.<br>Other: Saliva sample<br>* Subjects will have saliva collected by a member of the study team using a cotton swab.<br>Other: Smoking Status questions<br>* Subjects will be asked to complete an assessment asking questions about his/her current smoking status<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of patients with biochemically confirmed smoking cessation | Biochemical confirmation will be determined by saliva samples | 4 weeks after enrollment | 
| Number of patient who self-report smoking cessation | Self-reported smoking cessation will be documented via smoking assessment questionnaire | 4 weeks after enrollment | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Average weekly smoke exposure | reported cigarettes per day multiplied by the number of days smoked during radiation therapy (RT), summed over a period of time and normalized to yield an average weekly smoke exposure during RT. | up to 62 weeks | 
| Number of patients who participate in smoking cessation | Completing one in-person visit where an individualized smoking cessation treatment plan is developed and implemented. | up to 12 months after completion of RT. | 
| Compliance with smoking cessation | Two binary measure of compliance: - completing at least three in person visits within 6 weeks of starting an individualized cessation treatment plan - completing at least one in-person visit and at least two phone-based communications | up to 12 weeks after completion of RT |