Effect of Duration and Follicle Diameter During Oocyte Pick up on Embryological Parameters

Study Overview
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Brief Summary
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Investigators aim to investigate if the time spent for smaller follicles worth to deal with. The difference between follicle groups are recorded for embryological parameters. Results will be analysed for yielding transfer embryo and pregnancy rates between groups.

Detailed Description
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There are papers about follicle dimensions and volumes studying their effect on embryologic parameters. But most of these studies are far from practical approach and are not easily applicable, such as 3D volumetric measurement is not feasible for most of the clinics. Also one of the points important for us it to evaluate the duration of the procedure and the possible positive effect of shortening the duration for better results. Investigators plan to measure the follicles just before puncture and arrange two groups. Group 1,follicles with diameter of 17 mm and more, and group 2 follicles between14-17 mm. Maturation, fertilization, cleavage characteristics are recorded. The source of chosen transfer embryo and crio-preserved embryos per cycle is also point of interest.

Official Title
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Does Follicle Diameter and Total Duration Spent for Oocyte Pick up Has Any Effect on Embryological Parameters and Clinical Pregnancy Rates

Conditions
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Follicle Size, Embryologic Parameters, Duration

Intervention / Treatment
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* Procedure: follicle diameter and duration of procedure


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 20-40 year old women Exclusion Criteria: History of recurrent implantation failure (RIF) Known chromosomal abnormality Severe male factor and azospermia

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 40 Years

Sexes Eligible for Study
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Female

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| group 1<br>follicles with a diameter of 17 mm and more | Procedure: follicle diameter and duration of procedure<br>* to investigate if smaller follicles thrive embryos as the bigger follicles<br>* Other names: success rates;|
| group 2<br>follicles with a diameter of 14 mm to 17 mm | Procedure: follicle diameter and duration of procedure<br>* to investigate if smaller follicles thrive embryos as the bigger follicles<br>* Other names: success rates;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| transfer embryo | comparing groups as the source of transfer embryo | 5 to 7 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| clinical pregnancy | comparing groups as the source of implanted embryo | 3 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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follicle, dimension, IVF, embryological parameters, duration