Clinical Performance of Two Cad-cam Fabricated Ceramic Restoration in Teeth Affected With MIH

Study Overview
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Brief Summary
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This study will be performed to evaluate the clinical performance (Plaque accumulation, fracture of (restoration or tooth), postoperative sensitivity, secondary caries, marginal fit and discoloration) of two CAD/CAM fabricated ceramic restorations (zirconia-reinforced lithium silicate glass ceramic and hybrid ceramic) with different preparation designs (modified occlusal veneer and endocrown) for rehabilitation of permanent first molars affected with different severity level of molar incisor hypomineralisation (MIH), evaluated at different time periods

Detailed Description
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Clinical evaluation of all restorations will be performed according to: - Modified United States Public Health Service (USPHS) Ryge Criteria, at base line (1 week), 3, 6 and 12 months after cementation.

Official Title
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Clinical Performance of Two CAD/CAM Fabricated Ceramic Restorations With Different Preparation Designs for Rehabilitation Of Permanent First Molars Affected With Molar Incisor Hypomineralisation (MIH): Clinical Randomized Trial

Conditions
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Molar Incisor Hypomineralization

Intervention / Treatment
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* Procedure: occlusal veneer restorations
* Procedure: endocrown restorations


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria:- Patient from 8 to 13 years permanent first molar tooth affected with different severity levels of MIH Ability to physically and psychologically tolerate conventional restorative procedures. Exclusion Criteria:. Patients have active periodontal diseases. Patient with poor oral hygiene and motivation. Patient with psychiatric problems or unrealistic expectations

Ages Eligible for Study
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Minimum Age: 8 Years
Maximum Age: 13 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Randomized controlled trial (RCT)
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: OV group<br>Patients will receive occlusal veneer restorations | Procedure: occlusal veneer restorations<br>* occlusal veneer preparation with circumferential chamfer finish line and proximal slot  proposed modified occlusal veneer design for rehabilitation of moderate level of permanent first molars. OrPatients will receive endocrown restorations for rehabilitation of sever level of permanent first molars<br>|
| Experimental: EN group<br>Patients will receive endocrown restorations | Procedure: endocrown restorations<br>* endocrown restorations<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| retention | Clinical evaluation of all restorations will be performed according to: - Modified United States Public Health Service (USPHS) Ryge Criteria,at12 month after cementation | 1 year | 
| marginal integrity | Clinical evaluation of all restorations will be performed according to: - Modified United States Public Health Service (USPHS) Ryge Criteria, at 6 months after cementation | 6 months | 
| colour stability | Clinical evaluation of all restorations will be performed according to: - Modified United States Public Health Service (USPHS) Ryge Criteria, at 12 months after cementation | 12 months | 
| Elimination of sensitivity | Clinical evaluation of all restorations will be performed according to: - Modified United States Public Health Service (USPHS) Ryge Criteria, at 3, months after cementation | 3 months |