14y Prospective Study on Posterior Zirconia-based 3-unit FDPs

Study Overview
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Brief Summary
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The main objective of the present prospective study is to evaluate the effectiveness of posterior zirconia FDPs after 14 years of function.

Detailed Description
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thirty-seven patients needing to replace either premolars or molars were involved and 48 3-unit zirconia-based FDPs were fabricated. Patients included in the present clinical study met specific inclusion criteria and clinical procedures were standardized. Frameworks with a 9 mm2 cross section of the connectors and 0.6 mm minimum thickness of the retainers were made by means of Computer Aided Design/Computer Assisted Manufacturing. A resin cement was used to lute the restorations. The patients were recalled after 6 and 12 months and then yearly up to a total follow-up of 14 years. The United States Public Health Service criteria were used in order to examine technical and esthetic outcomes. Success and survival rates

Official Title
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Fourteen-year Evaluation of Posterior Zirconia-based Three-unit Fixed Dental Prostheses. A Prospective Clinical Study of All Ceramic Prosthesis

Conditions
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Prosthesis Survival

Intervention / Treatment
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* Other: 2 zirconia FDPs
* Other: 1 zirconia FDP


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: good general health; ASA I or ASA II according to the American Society of Anesthesiologists; good periodontal health; Angle class I occlusal relationship; minimum of 20 teeth; good oral hygiene; no evident signs of occlusal parafunctions and/or temporo-mandibular disorders. Moreover, the abutment teeth had to fulfill the following inclusion criteria: periodontal health (absence of tooth mobility, absence of furcation involvement); proper positioning in the dental arch (tooth axes adequate for a FDP); sufficient occlusal-cervical height of the clinical crown (≥4 mm) for the retention of a FDP; vital or endodontically treated to a clinically sound state; opposing natural teeth or fixed prostheses. Exclusion Criteria:- subjects preferring implant-supported prostheses; high caries activity; occlusal-gingival height of the abutment teeth <4 mm; reduced interocclusal distance or supraerupted opposing teeth; unfavorable crown-to-root ratio; severe wear facets, clenching, bruxism; presence of removable partial dentures; pregnancy or lactation.

Ages Eligible for Study
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Minimum Age: 21 Years
Maximum Age: 68 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| 2 zirconia FDPs<br>11 patients received 2 zirconia fixed dental prostheses | Other: 2 zirconia FDPs<br>* The United States Public Health Service criteria were used in order to examine technical and esthetic outcomes. Success and survival rates of the zirconia FDPs were calculated. The biological examination was performed analyzing both abutments and contralateral teeth.<br>|
| 1 zirconia FDP<br>26 patients received 1 zirconia FDP | Other: 1 zirconia FDP<br>* The United States Public Health Service criteria were used in order to examine technical and esthetic outcomes. Success and survival rates of the zirconia FDPs were calculated. The biological examination was performed analyzing both abutments and contralateral teeth.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Survival and success rate of zirconia FDPs | The 14-year cumulative survival rate of the zirconia FDPs was calculated by means of Kaplan-Meier analysis. | 14 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Technical and aesthetic outcomes | The United States Public Health Service criteria were used in order to examine technical and esthetic outcomes. | 14 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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zirconia, all ceramic prosthesis, prosthodontics, fixed dental prosthesis, prosthetic dentistry, prospective clinical study