Effectiveness of a Case Management Algorithm: ALGOS After a Suicide Attempt

Study Overview
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Brief Summary
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The suicidal behaviors are phenomena eminently multifactorial. It is thus always difficult to define univocal strategies of prevention of suicide repetition, during the emergency stay, i.e. almost in general population. One find 23 clinical trials in this topic in the past 25 years, and 18 are negative. The majority of the positive trials have the concern of being dissociated from an assumption of responsibility of care strictly speaking, to adopt a position méta, nearer to the concept of case management: how to remain in contact with the suicide attempter, without forcing it in this every day life, replacing a possible proposing, but assumption of responsibility resources reliable and quickly accessible in the event of at risk situation? Each one of these studies tests devices which seem more appropriate to such or such characteristic of this population, by retaining only simple criteria like the sex, the number of former suicide attempts, the proposal or not for an assumption of responsibility of care, the observance or not with the plan of care. Thus, it would seem interesting to combine these approaches in an algorithm entitled ALGOS. Main aim: To test the effectiveness of this algorithm of case management, named ALGOS, in reducing the number of death by suicide, in terms of reduction of suicide re-attempts and the number of loss of contact patients in the ALGOS group during 6 months period, compared to a control group of suicide attempters treated as usual (i.e. primarily transmitted to the attending physician). Secondary objectives: To evaluate, according to the method validated by Beecham in 1992, direct medico-economic impact in the year which follows the introduction of algorithm ALGOS. Reduction of the other suicidal behaviors in 6 months (reduction in the full number of suicidal repetitions in each group, evolution of the score of suicidal ideation, etc…). To evaluate the effect of the algorithm, at the 13th month. To study the possible differences within the time in terms of suicidal repetitions in the 2 groups. To propose different profiles of answers according to psychopathology, the number of suicide attempts, suicidal character, the sex,… Methodology: Comparative simple blind prospective multicentric controlled study

Detailed Description
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Evaluations: The subjects will be included in the participating centers following a suicide attempt (SA). After checking of the criteria, information and signature of the study consent, the subjects will be randomized in one of the 2 groups (ALGOS versus Control). A fax of inclusion will be sent to the centralized research team of the Clinical Investigation Center (CIC) of Lille. All the subjects included will be then evaluated at the 6th month and 13th month after the SA, during a phone call. The final evaluation will be carried out in the current of the 13th month, so as to avoid a recontact at the time of the period birthday, too charged affectively at the majority with the patients. This phone call, personal, will be carried out by an trained psychologist. A mail preventing the subject of the call will be addressed approximately 10 days before. During the evaluations at the 6th month and 13th month, the number of suicidal repetitions will be reported, consumption of care since inclusion will be noted, the scale of suicidal ideation of Beck assessed, and a psychopathological evaluation carried out (Mini International Neuropsychiatric Interview DSM IV).

Official Title
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Effectiveness of a Case Management Algorithm After a Suicide Attempt in Terms of Repetition of the Suicidal Behaviors and Medico-economic Impact

Conditions
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Suicide, Attempted

Intervention / Treatment
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* Behavioral: ALGOS algorithm of case management


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Surviving to a suicide attempt (SA) directly leaving the Emergency unit or have been hospitalized less than 7 days Exclusion Criteria: recidivists who made 4 SA and more in the 3 past years

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: ALGOS group<br>Algorithm of case management over the 6 months following the suicidal gesture (systematic telephone contact, postcards and crisis card) | Behavioral: ALGOS algorithm of case management<br>* If the subject survives one 1st SA (first attempter): he leaves the center where he was included with a chart resource (crisis card) which contains addresses of the Web sites of associations of prevention of the suicide, as well as an accessible phone number 24/24h. If the subject is not a first attempter : he will be recontacted on the telephone between the 10th and the 21st day following the SA. If the subject is not contacted or little observing in the plan of care, it will receive a series of postcards then regularly, with 4 recoveries: to 2, 3, 4 and 5 months after the attempt.<br>* Other names: ALGOS Group;|
| No Intervention: Control group<br>Treatment as usual (referral back to the general practitioner) | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of suicide re-attempters | the number of suicide re-attempters 6 months following the attempt index | six months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of deaths per suicide | Number of suicide re-attempts in the 6 months following the attempt index | six months and 13 months | 
| Number of lost to follow up |  | six months and 13 months | 
| Number of suicide re-attempters |  | 13 months | 
| Number of suicide re-attempts | Number of suicide re-attempts in the 6 months following the attempt index | six months and 13 months | 
| Suicidal ideation intensity | The suicidal ideation will be measured by Scale of Suicidal Ideation (A. Beck, M. Kovacs, and A. Weissman, 1979) in the 6 months following the attempt index and in the 13 months. | six months and 13 months | 
| medical cost | Numbers of hospitalisations, numbers of consultations, and drugs consummation during the year following the suicide attempt will be measured to estimate the medical cost | six months and one year | 
| Evaluation of the psychopathological profile | The psychopathological profile will be evaluated by the French version of Mini International Neuropsychiatric Interview (DSM IV) | six months and 13 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Suicide, case management algorithm, suicidal behaviors, prevention of suicide