linjc16/ctgov huggingface dataset:
A Comparison of Recall Rates Between Conventional 2d Mammography and 2d Plus 3d (Tomosynthesis) Mammography in a Screening Population

Study Overview
=================
Brief Summary
-----------------
The primary aim of this study is to measure, document and compare recall rates of two-dimensional plus three dimensional (2D plus 3D) (Tomosynthesis) mammography to that of 2D mammography in a screening population. This study will compare recall rates for both non-cancer and cancer cases.

Official Title
-----------------
A Comparison of Recall Rates Between Conventional 2d Mammography and 2d Plus 3d (Tomosynthesis) Mammography in a Screening Population

Conditions
-----------------
Breast Cancer

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Subject is female of any race and ethnicity The subject is asymptomatic and presents for routine screening mammography and chooses to have a combination 2D + 3D mammogram as her standard of care. Exclusion Criteria: Patient chooses standard 2D mammography over a combination 2D + 3D mammogram

Ages Eligible for Study
-----------------
Minimum Age: 30 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| screening<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Recall Rate | measure, document and compare recall rates of two-dimensional plus three dimensional (2D plus 3D) (Tomosynthesis) mammography to that of 2D mammography in a screening population | up to 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cancer detection Rate |  | up to 1 year | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
breast cancer screening, tomosynthesis, FFDM
DPBRN Longitudinal Study of Repaired or Replaced Dental Restorations

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to assess the quality and expected lifespan of fillings recorded in the DPBRN Reasons for replacement and repair of dental restorations study, and the factors affecting how long the fillings last.

Detailed Description
-----------------
The study is an observational follow-up of previously placed dental restorations (fillings)and is conducted during routing dental care visits.

Official Title
-----------------
Longitudinal Study of Repaired or Replaced Dental Restorations

Conditions
-----------------
Dental Caries

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: participant in the DPBRN Reasons for replacement or repair of dental restorations study

Ages Eligible for Study
-----------------
Minimum Age: 6 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Dental caries assessment<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Dental Caries, Assessment, dental materials
Evaluation of Diprospan Injection to the Knee on Rehabilitation of Patients After TKR of the Contralateral Knee

Study Overview
=================
Brief Summary
-----------------
This study is performed to assess the influence of intraarticular injection of 2ml Diprospan (wich contains 4mg Betamethasone sodium phosphate and 10mg Betamethasone dipropionate) into osteoarthritic knee in patients who undergo a total knee replacement of their contralateral knee. The study population will include 50 patients with bilateral knee osteoarthritis, admitted for their first knee replacement surgery. Only patients with older than 50 years with primary osteoarthritis will be included. The patients will be randomized into 2 groups. Intervention group will receive an injection of 2ml Diprospan diluted in 10 ml Bupivocaine. The control group will receive an injection of 10ml of Bupivocaine. All patients will be followed after 6 weeks and three functional rehabilitation and pain scores will be assessed (VAS pain score, Timed Up and Go Score and Functional Ambulatory Category Scale).

Official Title
-----------------
Evaluation of the Efficacy of Diprospan Injection to the Knee on Rehabilitation of Patients With Bilateral Knee Osteoarthritis After TKR of the Contralateral Knee.

Conditions
-----------------
Osteoarthritis

Intervention / Treatment
-----------------
* Drug: Betamethasone
* Drug: Bupivocaine


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age older than 50 Bilateral primary knee osteoarthritis Undergoing knee arthroplasty Exclusion Criteria: Active infection Allergy to medication compounds Pregnancy

Ages Eligible for Study
-----------------
Minimum Age: 50 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 1<br> | Drug: Betamethasone<br>* Intraarticular injection of 2ml Diprospan (wich contains 4mg Betamethasone sodium phosphate and 10mg Betamethasone dipropionate)<br>|
| Active Comparator: 2<br> | Drug: Bupivocaine<br>* Intraarticular injection of 10ml of Bupivocaine<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual analogue pain score |  | 6 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Timed Up and Go Score |  | 6 weeks | 
| Functional Ambulatory Category Scale |  | 6 weeks | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Osteoarthritis, Knee arthroplasty, Steroid injection, Rehabilitation
LSA4 Protocol for the Treatment of Advanced Pediatric and Adolescent Non-Hodgkins Lymphoma

Study Overview
=================
Brief Summary
-----------------
Non-Hodgin's lymphoma is curable in 76% of patients. In nonlymphoblastic lymphmas, cancer may return on average 3 months from beginning treatment and for lymphoblastic lymphomas, 6 months. To aggressively treat this cancer this study uses effective drugs in three parts: Induction ends on day 19 Consolidation ends on day 38 or 42 Maintenance may include up to 6 cycles

Official Title
-----------------
LSA4 Protocol for the Treatment of Advanced Pediatric and Adolescent Non-Hodgkins Lymphoma

Conditions
-----------------
Non-Hodgkin's Lymphoma

Intervention / Treatment
-----------------
* Drug: LSA4, Cyclophosphamide, Methotrexate, Daunomycin, L-asparaginase, BCNU


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Non-Hodgkin's Lymphoma stages III, IV, IVA with T cell lymphomas, any primary site irrespective of LDH level large cell lymphomas, any primary site irrespective of LDH level B cell lymphomas, any primary site with initial LDH of less than 500 Exclusion Criteria: B cell lymphomas, any primary site with initial LDH of less than 500 and initial CNS or bone involvement

Ages Eligible for Study
-----------------
Maximum Age: 21 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 1 - LSA4<br> | Drug: LSA4, Cyclophosphamide, Methotrexate, Daunomycin, L-asparaginase, BCNU<br>* LSA4 intervention includes three phases: induction, consolidation and maintenance<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Complete Remission | The number of patients who achieved a complete remission as a result of treatment | 330 Days |
Effect of Sugammadex for Reversal of Rocuronium-induced Neuromuscular Block on Perioperative Management of Awake Craniotomy

Study Overview
=================
Brief Summary
-----------------
Effect of sugammadex for reversal of rocuronium-induced neuromuscular block on Perioperative Management of awake Craniotomy

Official Title
-----------------
Effect of Sugammadex for Reversal of Rocuronium-induced Neuromuscular Block on Perioperative Management of Awake Craniotomy

Conditions
-----------------
Brain Tumors

Intervention / Treatment
-----------------
* Drug: sugammadex


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age: 18-45 years old body mass index (BMI)≥ 18.5-23.9 kg/m2, ASA grade I  II. Exclusion Criteria: Suffering from a mental illness or preoperative communication disorder, patients with claustrophobia, breathing, circulation, neuromuscular system and kidney, and other important viscera function disorder, pregnant or lactating women, a history of malignant hyperthermia, the history of drug allergy in the process of general anesthesia and recent may not used to the interaction between rocuronium, vecuronium bromide reacts drugs (such as aminoglycoside antibiotics, Anticonvulsant, magnesium).

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Sugammadex Group<br>rocuronium-induced general anesthesia，use of sugammadex antagonism | Drug: sugammadex<br>* The use of sugammadex<br>* Other names: Org 25969;|
| No Intervention: Control Group<br>general anesthesia without rocuronium | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| awake time | The time between asleep and awake | 10-30 minutes | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
sugammadex、awake craniotomy
Chronic Kidney Disease and Cardiovascular Disease Risk Assessment

Study Overview
=================
Brief Summary
-----------------
This study will investigate chronic kidney disease (CKD) and cardiovascular disease (CVD) risk factors in a sample population of Hispanics/Latinos and Caucasians in Yakima county that are rural dwelling. This investigation is intended to provide information on the impact rural geographical location and social determinants of health (SDOH) have on CKD and CVD risk factors.

Detailed Description
-----------------
Yakima County has a large hispanic farmworker population. The peak work times are between May and September. There is a growing body of research that shows the risk of agricultural workers in work environments with extreme heat. The purpose of this pilot study is to look at incidence of non-diagnosed chronic kidney disease within Yakima County to inform future studies to examine other factors and unique bio-markers that may help in the early diagnosis of heat related injuries in agricultural workers.

Official Title
-----------------
Chronic Kidney Disease and Cardiovascular Disease Risk Assessment in Yakima County

Conditions
-----------------
Chronic Kidney Diseases, Diabetes Mellitus, Hypertension

Intervention / Treatment
-----------------
* Diagnostic Test: Hemoglobin A1C
* Diagnostic Test: Urinalysis
* Diagnostic Test: Whole blood creatinine level


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Between the ages of 18 and 75 Exclusion Criteria: Active malignancy Currently pregnant End stage renal disease requiring dialysis Current active treatment for diabetes mellitus Current care by a nephrologist for chronic kidney disease

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: Hemoglobin A1C|Finger stick hemoglobin A1C|
|Diagnostic Test: Urinalysis|Urinalysis by dip stick looking for urine protein level|
|Diagnostic Test: Whole blood creatinine level|Finger stick looking for serum creatinine as an estimate of renal function|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of undiagnosed chronic kidney disease in farmworkers in Yakima County, WA | Finger stick and urinalysis will be done at the time of screening | At the time of screening | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of undiagnosed diabetes mellitus in farmworkers in Yakima County, WA | Finger stick will be done at the time of screening | At the time of screening | 
| Incidence of undiagnosed hypertension in farmworkers in Yakima, County, WA | Measurement of blood pressure | At the time of screening |
Intelligent Sports Injury Prevention and Training System

Study Overview
=================
Brief Summary
-----------------
Sports injuries are a very important issue for baseball players. Previous studies have found that the incidence of sports injuries faced by baseball players is continuously increasing. Sports injury rates in professional baseball, high school baseball, and college baseball players were as high as 3.6, 4.6, and 5.8 per 1,000 players, respectively. The main cause of many pitching injuries is attributed to a large number of repetitive pitches. To avoid sports injuries, it is necessary to know how to assess the risk of injury caused by repetitive pitching. Throwing is a fairly complex action that requires the coordination of the entire body. It is critical to investigate the biomechanical changes of players in order to effectively analyze such complex movements.

Official Title
-----------------
SportSense 6D Fusion - Application of Multi-sensor Fusion Environment in Movement, Training and Injury Prevention in Bat and Arm Swing Sports-Intelligent Sports Injury Prevention and Training System

Conditions
-----------------
Sport Injury

Intervention / Treatment
-----------------
* Other: Lower extremity and core muscle training


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Healthy baseball pitchers Age between 18 55 years old Exclusion Criteria: Surgery history in pitching arm Musculoskeletal disease Neuromuscular disease

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 55 Years

Sexes Eligible for Study
-----------------
Male

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Baseball pitcher training<br> | Other: Lower extremity and core muscle training<br>* Lower extremity training: single leg balance training Core muscle training: pelvic control training<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Countermovement jump (CMJ) | Test CMJ before and after training | 6 weeks |
Impact of Preoperative Hypocaloric Hyperproteinic Lipid Restricting Diet on Bariatric Surgery

Study Overview
=================
Brief Summary
-----------------
Obesity is one of the greatest pandemics of the 21st century with 30 million new cases each year. In France each year, 60,000 bariatric surgery procedures are performed. Many preoperative diets have been proposed in the literature with some studies giving positive results. But these diets are often strict and can have adverse effects on metabolism. Very few studies have described the PSMF diet. The hypothesis would be that this diet is associated with a reduction in liver volume with a reduction in steatosis.

Official Title
-----------------
Impact of Preoperative Hypocaloric Hyperproteinic Lipid Restricting Diet on Bariatric Surgery

Conditions
-----------------
Obesity, Abdominal

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion criteria: Adult patient (≥18 years old) Man and woman Patient operated on at the HUS between 2010 and 2021 for bariatric surgery Patient not objecting to the reuse of their data for scientific research purposes. Exclusion criteria: - Patient who has expressed his opposition to the reuse of his data for scientific research purposes.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| liver volume measurement in cm |  | Files analysed retrospectively from Ocober 01, 2010 to December 31, 2021 will be examined | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Obesity, Abdominal, Preoperative diets, PSMF diet
Antidepressant Drug Exposure and Risk of Suicide Attempt Resulting in Medical Intervention in US Adults

Study Overview
=================
Brief Summary
-----------------
The primary objective of the study is to estimate the incidence of suicide attempts resulting in a medical encounter or hospitalization in seven propensity matched cohorts of subjects: patients treated with duloxetine for depression, patients treated with one of three other antidepressants or antidepressant classes (venlafaxine, SSRIs, or TCAs) for depression, patients treated with multiple antidepressants for depression (either concurrently or consecutively), depressed patients with no pharmacologic treatment, and a non-depressed general population sample.

Official Title
-----------------
A Propensity-Matched Retrospective Cohort Study of Antidepressant Drug Exposure and Risk of Suicide Attempt in Adults From a Large U.S. Managed Care Population

Conditions
-----------------
Depression, Suicide

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age 18 years or older at index date Have at least 6 months of continuous enrollment data prior to index date. Have complete medical, facility, and pharmacy records (the latter of which will include complete quantity and days supplied information). Exclusion Criteria: None

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| 1<br>Duloxetine | |
| 2<br>Venlafaxine | |
| 3<br>SSRI | |
| 4<br>TCA | |
| 5<br>Multiple Antidepressants | |
| 6<br>Depressed (not antidepressant treated) | |
| 7<br>General population | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of suicide attempt resulting in medical encounter or hospitalization. |  | Endpoint | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Relative risk of suicide attempt resulting in medical encounters or hospitalization |  | Endpoint |
Behavioral and Pharmacological Treatment for Insomnia

Study Overview
=================
Brief Summary
-----------------
This study will evaluate the long- and short-term effects of cognitive-behavior therapy (CBT), alone and in combination with zolpidem (Ambien®), for chronic insomnia.

Detailed Description
-----------------
Insomnia is a prevalent health concern which is often associated with functional impairments, reduced quality of life, and increased health-care costs. The proposed study may provide useful information about optimal models for integrating behavioral and pharmacological therapies for the clinical management of insomnia. Participants are randomly assigned to CBT or CBT plus medication. After the 6-week acute treatment phase, participants enter into a 6-month extended treatment phase. Of those treated with CBT alone initially, responders are randomized to extended CBT or no treatment. Of those receiving the combined CBT plus medication approach initially, responders are randomized to an extended treatment consisting of either CBT plus medication (used on an as needed schedule) or CBT alone (plus medication tapering). Outcome is evaluated across measures of sleep, clinical ratings, and several indices of daytime functioning. The measures are administered at baseline, at the end of the acute and extended treatment phases, and at 6, 12, and 24-month follow-up.

Official Title
-----------------
Behavioral and Pharmacological Treatment for Insomnia

Conditions
-----------------
Sleep Initiation and Maintenance Disorders

Intervention / Treatment
-----------------
* Behavioral: Cognitive-behavior therapy
* Drug: zolpidem


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion criteria: Subjective complaint of difficulties initiating or maintaining sleep, accompanied by marked distress or daytime impairments due to insomnia Sleep difficulties present 3 nights or more per week and lasting for more than 6 months Exclusion criteria: Major medical or psychiatric problems

Ages Eligible for Study
-----------------
Minimum Age: 30 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: Cognitive-behavior therapy|nan|
|Drug: zolpidem|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Insomnia, Sleep Disorders, Sleep Deprivation