PRF Pulpotomy Using Different Bioceramic Materials in Permanent Molars

Study Overview
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Brief Summary
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this study aimed to compare the clinical and radiographic outcomes of full pulpotmy after application of Biodentine, or MTA, or Portland cement above PRF membrane In permanent molars with irreversible pulpitis

Official Title
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Outcome of PRF Pulpotomy Using Different Bioceramic Materials in Permanent Molars With Irreversible Pulpitis: A Randomized Controlled Trial

Conditions
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Irreversible Pulpitis

Intervention / Treatment
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* Procedure: portland cement
* Procedure: Mineral trioxide aggregate
* Procedure: Biodentine


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: spontaneous, lingering pain exacerbated by hot and cold , and/or radiating pain Responded to cold and electric pulp testing Exclusion Criteria: pain on palpation, percussion, mobility or swelling peridontall widening Teeth with marginal periodontitis or crestal bone loss resorption calcified canals

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 40 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: permanent molar with symptomatic irreversible pulpitis
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Portland cement<br>pulpotomy with PRF and white Portland cement | Procedure: portland cement<br>* pulpotomy with PRF and white Portland cement<br>|
| Experimental: Mineral trioxide aggregate<br>pulpotomy with PRF and Mineral trioxide aggregate | Procedure: Mineral trioxide aggregate<br>* pulpotomy with PRF and white Mineral trioxide aggregate<br>|
| Experimental: Biodentine<br>pulpotomy with PRF and Biodentine | Procedure: Biodentine<br>* pulpotomy with PRF and Biodentine<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in postoperative pain | persistence , relief , or exacerbation of pain using visual analogue scale for pain score | 24 hours, 48 hours, 1 week, every 3 months for 12 months | 
| Change in swelling | appearance of periapical swelling or facial swelling after the clinical procedures (Binary outcome: Yes/No) | 24 hours, 48 hours, 1 week, every 3 months for 12 months | 
| Change in Mobility | appearance of teeth mobility after the clinical procedures (record of periodontal pocket depth) | 24 hours, 48 hours, 1 week, every 3 months for 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| calcific like bridge | measure of the calcific bridge thickness using CBCT | 12 month | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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PRF, Vital pulp therapy, pulpotomy, bioceramics