The Influence of Different Mood States and Emotions on the Physiologic, Metabolic, and Perceptual Responses to Feeding Before Exercise

Study Overview
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Brief Summary
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Many athletes anecdotally report modifying their nutritional intake before competition in order to avoid gut problems, but no studies have evaluated whether emotional state impacts tolerance to pre-exercise feeding. Therefore, this study will use movie clips (stressful, horror, and funny/amusing) to induce different mood states and emotions, which will be followed by ingestion of food before endurance running on a treadmill. In addition, metabolic and physiologic responses to mood induction will be evaluated.

Official Title
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The Influence of Different Mood States and Emotions on the Physiologic, Metabolic, and Perceptual Responses to Feeding Before Exercise

Conditions
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Other Gastrointestinal Disorders, Cramp, Abdominal

Intervention / Treatment
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* Other: Funny/Amusing Video Clips
* Other: Horror/Scary Video Clips
* Other: Thrilling/Suspenseful Video Clips


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Aged 18 to 55 years Able to run for 30 min at a moderate-to-vigorous intensity without stopping No diagnosis or signs/symptoms of cardiovascular disease (CVD) or metabolic disorders Currently physically active (at least 3 days/week of exercise at a moderate or higher intensity) No visual or hearing impairments interfering with ability to see and hear video clips No allergies to ingredients in Boost drink Exclusion Criteria: Aged <18 or >55 years Unable to run for 30 min at a moderate-to-vigorous intensity without stopping A diagnosis or signs/symptoms of CVD or metabolic disorders Currently physically inactive (< 3 days/week of exercise at a moderate or higher intensity) Visual or hearing impairments interfering with ability to see and hear video clips Allergies to ingredients in Boost drink

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 55 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Funny/Amusing Video Clips<br>Participants will watch 5-7-min video clips that are meant to be funny/amusing | Other: Funny/Amusing Video Clips<br>* Participants watch 5-7 minutes of video clips that are funny/amusing in nature<br>|
| Experimental: Horror/Scary Video Clips<br>Participants will watch 5-7-min video clips that are meant to be scary | Other: Horror/Scary Video Clips<br>* Participants watch 5-7 minutes of video clips that are scary in nature<br>|
| Experimental: Thrilling/Suspenseful Video Clips<br>Participants will watch 5-7-min video clips that are meant to be thrilling/suspenseful | Other: Thrilling/Suspenseful Video Clips<br>* Participants watch 5-7 minutes of video clips that are thrilling/suspenseful in nature<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Total exercise gastrointestinal symptom burden | The severity of several gastrointestinal symptoms will be assessed on a validated 0-10 scale. Ratings will be collected every 5 minutes during a 30-minute treadmill jogging/running test. Scores from every 5-minute collection will be summed to calculate total GI symptom scores. | Total GI symptom burden over a 30-minute jogging/running protocol. | 
| Change in emotion ratings | Anxiety, fear, happiness, amusement, disgust, sadness, and anger on a 0-9 Likert scale. Emotions will be assessed before watching video clips and immediately after watching video clips. | Change in emotion ratings between immediately pre-video and immediately post-video. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change over time in exercise heart rate | Heart rate will be measured with a chest-strap (Polar) monitor. | Heart rate will be measured throughout a 30-minute treadmill jogging/running test. Change over time will be evaluated using mixed ANOVA. | 
| Substrate use | Carbohydrate and fat oxidation rates will be estimated from the volumes of oxygen consumption and carbon dioxide production during exercise | Carbohydrate and fat oxidation rates will be measured during the last 5 min of a 30-minute treadmill jogging/running test. | 
| Feeling Scale | The Feeling Scale is a bipolar numerical rating scale ranging from -5 to +5, with descriptors of very bad at -5, neutral at 0, and very good at +5. | Ratings on the Feeling Scale will be measured at rest before watching video clips and throughout (every 5 min) a subsequent 30-minute treadmill jogging/running test. | 
| Fatigue Scale | The Fatigue Scale is Likert-type scale that ranges from 0 (Not Fatigued at All) to 10 (Total Fatigue). | Ratings on the Fatigue Scale will be measured at rest before watching video clips and throughout (every 5 min) a subsequent 30-minute treadmill jogging/running test. | 
| Heart rate post-video | Heart rate will be measured with a chest-strap (Polar) monitor. | Heart rate will be recorded immediately after videos are viewed. |