Enhancing Social Interaction With an AlterEgo Artificial Agent

Study Overview
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Brief Summary
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The objective of AlterEgo is the creation of an interactive cognitive architecture, implementable in various artificial agents, allowing a continuous interaction with patients suffering from social disorders, by virtue of changes in behavioural (robot-based) as well as morphological (avatar-based) properties of that agent. The project includes research in fundamental and clinical neurosciences, interaction modeling, development of new computer-vision techniques and human-robot interfaces, as well as evaluation of the scenarios with patients before, during, and after training sessions. At the end of the project, the investigators will produce a new avatar-based clinical method able to enhance social interaction of patients. The first challenge of this project is to create an avatar alter ego of a patient. Based on recent work in social robotics and neurosciences, the investigators hypothesize that if patients face artificial agents morphologically and behaviourally similar to them, they will increase their social interaction. The second challenge is to transform the morphology and the behaviour of the similar artificial agent into that of a healthy and different agent. The investigators assume that the smooth and continuous behavioural shift from similar/unhealthy to complementary/healthy social behaviour will lead to a better social rehabilitation. AlterEgo opens the door to a new generation of social artificial agents in service robotics. AlterEgo is an interdisciplinary project at the interaction of Social Motor Neurosciences (UM1), Robotics (EPFL), Complex Systems Dynamics (UOB), Computer Vision (DFKI), and Psychiatry (CHU). This project includes a set of experiments that started in april 2014 and will terminate in september 2016 before undergoing a randomised clinical research.

Official Title
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Enhancing Social Interaction With an AlterEgo Artificial Agent

Conditions
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Schizophrenia

Intervention / Treatment
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* Other: Social Skills training with Avatar therapist


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients suffering from schizophrenia according to the criteria proposed in the DSM-IV-TR Aged between 18 and 60 years old. Exclusion Criteria: History of head trauma History of neurological disorders (epilepsy disease, multiple sclerosis, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, stroke) An actual ECT treatment Substance Abuse and / or current Substance dependence (excluding tobacco and cannabis). Pregnant women, new mothers and nursing mothers People private of their liberty

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Patients with schizophrenia<br>Patients with schizophrenia | Other: Social Skills training with Avatar therapist<br> <br> |
| Placebo Comparator: Healthy volunteers<br>Healthy volunteers | Other: Social Skills training with Avatar therapist<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| number of patient enhancing social intercation | improvement of social interactions (interpersonal relations, items 1 to 7 on Specific Levels Of Functioning, SLOF) | 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| number of patient accepting avatar therapy |  | 3 months | 
| questionnaire for Faisability of avatar therapy |  | 3 months |