Lumbar Intervertebral Motion in Asymptomatic Male Participants

Study Overview
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Brief Summary
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The investigators aim to analyze the physiological segmental motion of the lumbar spine during flexion and extension cinematographic recordings of asymptomatic individuals.

Detailed Description
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In this study the investigators aim to define the lumbar spines' physiological motion by analyzing sequence of initiation of motion and sequence of maximum contribution in segmental translation and rotation of each vertebra L1, L2, L3, L4, L5 and S1 by using flexion and extension cinematographic recordings in asymptomatic male participants. Participants will undergo two cinematographic recordings with an interval of two weeks. Segmental translation and rotation of each segment will be plotted against total range of motion of the lumbar spine for each individual participant. With these graphs the investigators can analyze if there are specific physiological motion patterns during flexion and extension of the lumbar spine. In the future, the investigators hope to compare these physiological motion patterns to potential abnormal motion patterns in patients suffering from lumbar spinal pathology or after lumbar spine surgery to gain knowledge about complaints and, for example, adjacent level disease.

Official Title
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Analysis of Lumbar Intervertebral Motion During Flexion and Extension Cinematographic Recordings in Asymptomatic Male Participants.

Conditions
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Lumbar Intervertebral Motion

Intervention / Treatment
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* Radiation: Cinematographic recording


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Male Age between 18 and 25 years old. BMI under 25 Participants have to be able to perform flexion and extension over a full range of motion without complaints of pain. Participants have no medical history of spinal problems based on anamneses and zero ODI-, and VAS-score. Kellgrens' classification on cinematographic recordings is zero or one. Informed consent has been signed. Ability to read and understand Dutch. Exclusion Criteria: Medical history of visiting general practitioners, allied health professionals or specialists for spinal problems. Former spine surgery. Radiographs of abdomen, pelvis, hips, lumbar spine or sacral spine in last year. Degenerative abnormalities of the lumbar spine. Active spinal infection. Immature bone. Lumbar tumor processes. Former lumbar radiotherapy. Congenital lumbar spine abnormalities, for example spina bifida. Planning pregnancy for the coming year.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 25 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Intervention Model: Single Group Assignment
Interventional Model Description: Fundamental research with 11 male participants in one study arm, all performingflexion and extension of the lumbar spine during cinematographic recordings twice.
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Cinematographic recording<br>Cinematographic recordings of the asymptomatic participants during flexion and extension of the lumbar spine.Cinematographic recordings will be performed twice with an interval of two weeks. | Radiation: Cinematographic recording<br>* Cinematographic recording during flexion and extension of the lumbar spine.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Lumbar segmental rotation | Analyzing sequence of initiation of motion and sequence of segmental contribution in rotation of each vertebra L1, L2, L3, L4, L5 and S1 by using flexion and extension cinematographic recordings in asymptomatic male participants. | 30 minutes | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Lumbar segmental translation | Analyzing intervertebral horizontal and vertical translation of each vertebra L1, L2, L3, L4, L5 and S1 by using flexion and extension cinematographic recordings in asymptomatic male participants. If mean intra-class correlation coefficient is higher than 0.60, sequence of initiation of motion and sequence of segmental contribution of intervertebral horizontal and vertical translation will be analyzed. | 30 minutes | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Lumbar intervertebral motion, Flexion, Extension, Cinematographic recording, Segmental rotations, Segmental translation, lumbar spine, asymptomatic participants