Effect of Preoperative Oral Carbohydrates on Quality of Recovery in Laparoscopic Colorectal Surgery Patients

Study Overview
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Brief Summary
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Preoperative midnight NPO is a traditional method for preventing aspiration during general anesthesia. However, recent studies reported that drinking carbohydrate beverage, three hours prior the surgery helps reducing patients starving, uncomfortment, and fatigue without other complication. QOR 40 is developed for evaluating patients' recovery condition regarding physical, psychological, and social aspects. Enhanced Recovery After Surgery(ERAS) is a concept for reducing patients' hospital stay and helping recovery. Studies showed that drinking carbohydrate beverage made better recovery of bowel function and shorter hospital stay in colorectal surgeries. However, the effect of carbohydrate drink for laparoscopic surgery is not yet proved. Therefore, the investigators will show the effect of carbohydrate drinking through this study.

Conditions
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Colorectal Disease

Intervention / Treatment
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* Dietary Supplement: carbohydrate beverage
* Dietary Supplement: NPO(None Per Oral)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients undergoing laparoscopic colorectal surgery, 20 85 year-old patients Exclusion Criteria: diabetes mellitus Inability to consume clear fluids GERD or gastrointestinal obstruction Liver cirrhosis corticosteroid treatment ASA>4 starting surgery five and more hours after drinking carbohydrate beverage pregnancy

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: carbohydrate group<br> | Dietary Supplement: carbohydrate beverage<br>* Carbohydrate group drinks carbohydrate beverage 400ml(9PM MN) the day before the surgery and 200ml three hours before the surgery.<br>|
| Placebo Comparator: NPO(None Per Oral) group<br> | Dietary Supplement: NPO(None Per Oral)<br>* NPO group does not drink any water from the MN before the surgery.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| total score of a survey using Quality of Recovery 40 |  | 1 day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| amount of perioperative water intake | measure with ml | 1 day | 
| amount of perioperative urine output | measure with ml | 1 day | 
| time to bowel function recovery |  | 1 day | 
| hospital stay duration from operation to discharge |  | 1 month | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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carbohydrate, quality of recovery(QOR) 40, enhanced recovery after surgery(ERAS)