Randomized Controlled Trial of Treating Migraine With Acupuncture

Study Overview
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Brief Summary
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The purpose of the study is to testify whether acupuncture is effective for migraine, and provide evidence for the hypothesis thatAcupuncture effect is based on meridians, and gathering of meridian Qi is the key point.

Detailed Description
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The purpose of the study is to testify whether acupuncture is effective for migraine, through treating migraine patients for a month, using different acupoints according to literatures of treating migraine with acupuncture, and try to provide clinical evidence for the hypothesis thatAcupuncture effect is based on meridians, and gathering of meridian Qi is the key point.

Official Title
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Randomized Controlled Trial of Treating Migraine With Acupuncture

Conditions
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Migraine

Intervention / Treatment
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* Other: acupuncture


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age of a subject is older than 18 and is younger than 65.(The subject is younger than 50 when he was ill for the first time.) Consistent with the diagnostic criteria of Premonitory Migraine and Non- Premonitory Migraine. Attacks of migraine are equal to or more than 2 times in the last three months. With more than one year history of migraine Informed consent is signed by a subject or his lineal relation. Exclusion Criteria: With serious protopathy or disease of cardiovascular, liver, renal,gastrointestinal, hematological systems and so on. Psychotic，patients with allergic constitution or easily getting infected or bleeding. Patients have used drugs for preventing migraine in the last four weeks. Pregnant women or women in lactation.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: group 1<br>specific acupoints of Shaoyang meridians | Other: acupuncture<br>* Subjects are treated five days a week continuously, and for four weeks.They are treated 30min every time.<br>* Other names: electro-acupuncture;|
| Experimental: Group 2<br>Non-specific acupoints of Shaoyang meridians | Other: acupuncture<br>* Subjects are treated five days a week continuously, and for four weeks.They are treated 30min every time.<br>* Other names: electro-acupuncture;|
| Experimental: group 3<br>Acupoints of other meridians | Other: acupuncture<br>* Subjects are treated five days a week continuously, and for four weeks.They are treated 30min every time.<br>* Other names: electro-acupuncture;|
| Sham Comparator: group 4<br>Non-acupoints | Other: acupuncture<br>* Subjects are treated five days a week continuously, and for four weeks.They are treated 30min every time.<br>* Other names: electro-acupuncture;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| number of days with migraine |  | 4 weeks | 
| frequency of migraine attacks |  | 4 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Migraine-Specific Quality-of-Life Questionnaire |  | a month | 
| Transcranial Doppler Sonography |  | a month | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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migraine, acupuncture, efficacy, safety, meridian, acupoint