Effect of the Transmuscular Quadratus Lumborum Block on Duration of Stay in Recovery

Study Overview
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Brief Summary
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The study will review data collected in 5 previously completed randomised controlled trials with a new primary outcome: to assess whether administration of the transmuscular quadratus lumborum block has an impact on the time an individual patient stays in the postanaesthesia care unit and how much opioid is consumed during this specified time.

Official Title
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Effect of the Transmuscular Quadratus Lumborum Block on Duration of Stay in Recovery: a Single-centre, Retrospective, Observational Study Based on Five Selected Randomised Controlled Trials

Conditions
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Anesthesia, Local

Intervention / Treatment
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* Drug: Ropivacaine injection


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: - Elective Surgery Exclusion Criteria: Inability to cooperate Allergy to local anaesthetics or opioids Inability to understand Danish Regular intake of opioids Local infection at site of injection

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Hemicolectomy, Active treatment<br>2x30mL 0.375% Ropivacaine administered by way of transmuscular quadratus lumborum block | Drug: Ropivacaine injection<br>* Transmuscular quadratus lumborum block - active<br>* Other names: Transmuscular quadratus lumborum block;|
| Hemicolectomy, Placebo treatment<br>2x30mL isotonic saline administered by way of transmuscular quadratus lumborum block | |
| Nephrectomy, Active treatment<br>2x30mL 0.375% Ropivacaine administered by way of transmuscular quadratus lumborum block | Drug: Ropivacaine injection<br>* Transmuscular quadratus lumborum block - active<br>* Other names: Transmuscular quadratus lumborum block;|
| Nephrectomy, Placebo treatment<br>2x30mL isotonic saline administered by way of transmuscular quadratus lumborum block | |
| Percutaneous nephrolithotomy, Active treatment<br>1x30mL 0.75% Ropivacaine administered by way of transmuscular quadratus lumborum block | Drug: Ropivacaine injection<br>* Transmuscular quadratus lumborum block - active<br>* Other names: Transmuscular quadratus lumborum block;|
| Percutaneous nephrolithotomy, Placebo treatment<br>1x30mL isotonic saline administered by way of transmuscular quadratus lumborum block | |
| Hysterectomy, Active treatment<br>2x30mL 0.375% Ropivacaine administered by way of transmuscular quadratus lumborum block | Drug: Ropivacaine injection<br>* Transmuscular quadratus lumborum block - active<br>* Other names: Transmuscular quadratus lumborum block;|
| Hysterectomy, Placebo treatment<br>2x30mL isotonic saline administered by way of transmuscular quadratus lumborum block | |
| Elective Caesarean section, Active treatment<br>2x30mL 0.375% Ropivacaine administered by way of transmuscular quadratus lumborum block | Drug: Ropivacaine injection<br>* Transmuscular quadratus lumborum block - active<br>* Other names: Transmuscular quadratus lumborum block;|
| Elective Caesarean section, Placebo treatment<br>2x30mL isotonic saline administered by way of transmuscular quadratus lumborum block | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Duration of recovery | Minutes from arrival in PACU to completed recovery (arrival until ready for departure) | 0-300 minutes | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Total time spent in recovery | Minutes from arrival in PACU to actual departure time (arrival until actual departure) | 0-300 minutes | 
| Duration of stay at PACU after completed recovery | Minutes from completed recovery to actual departure from PACU | 0-300 minutes | 
| Total opioid consumption in PACU | Total amount of opioid administered, converted to Oral Morphine Equivalents | 0-300 minutes | 
| Highest pain score in PACU | Highest reported Numeric Rating Scale of pain during stay in recovery | 0-300 minutes |