Case Volume and Adenoma Rate During Screening Colonoscopy

Study Overview
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Brief Summary
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Screening colonoscopy has been established as the most effective means of colorectal cancer prevention. This is based on the fact that colonoscopy detects and removes colonic polyps (adenomas) which are known to progress to cancer if left untreated. The present study examines the question whether case volume (i.e., the number of colonoscopies performed per year) correlates with colonoscopy quality, i.e., adenoma detection rate.

Detailed Description
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21 private practice gastroenterologist endoscopists from Berlin performed a prospective quality assessment study including at least 10.000 screening colonoscopies. After informed consent, patients data are included (age, sex, family history, colonoscopy performance parameters and findings, therapy performed, histology of biopsies and/or polypectomies, complications (immediate and late) and patient acceptance. The latter was retrieved by patient questionnaires returned after a minimum of 2 weeks. Data were centrally collected in an anonymized way Primary outcome parameter: Correlation of adenoma detection rate with case volume and other confounding factors (e.g., withdrawal time) Secondary outcome parameters: Complications and method of assessment (immediate recording versus later questionnaire enquiry) Quality of bowel preparation in relation to outcome Patient acceptance in relation to procedural factors (e.g., sedation) Quality of pathology reports and histologic outcome of polypectomy Later follow-up (after 5-10 years) of the preventive effect of colonoscopy is planned and has been part of the protocol and patient consent form.

Official Title
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Case Volume and Adenoma Detection Rates During Screening Colonoscopy

Conditions
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Colorectal Cancer

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: all persons willing and able to undergo screening colonoscopy over the age of 55 years Exclusion Criteria: any condition not compatible with the definition of screening colonoscopy

Ages Eligible for Study
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Minimum Age: 55 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| 1<br>Observational study on consecutive persons over the age of 55 years presenting for screening colonoscopy | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Correlation of adenoma detection rate with case volume of endoscopists |  | 18 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Patient acceptance in relation to procedural factors (e.g. sedation) |  | 18 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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colorectal cancer, prevention, colonoscopy, screening, quality assessment, colorectal cancer prevention