Protein Consumption in Critically Ill Patients

Study Overview
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Brief Summary
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A retrospective study of protein intake and needs as well as outcomes in critically ill adult patients. Data will be collected for up to 7 days of ICU stay.

Detailed Description
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This retrospective study of critically ill adults receiving enteral nutrition will assess the ability to meet estimated protein and energy needs via enteral nutrition.

Official Title
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Protein Consumption in Critically Ill Patients: A Retrospective Study

Conditions
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Critical Illness, Dietary Modification

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adult patients (age ≥18 years) Admitted to the ICU Administered at least one dose of enteral formula Exclusion Criteria: Receiving exclusive oral or exclusive parenteral nutrition

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Daily protein intake (from Parenteral Nutrition, Enteral Nutrition, oral diet, and medication) |  | Daily up to 7 days of ICU stay | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Enteral formula utilized (Standard, High protein, Very high protein) |  | Daily up to 7 days of ICU stay | 
| Daily caloric intake (from Parenteral Nutrition, Enteral Nutrition, oral diet, and medication) |  | Daily up to 7 days of ICU stay | 
| Estimated caloric needs (Kcal/day) |  | Daily up to 7 days of ICU stay | 
| Method for estimating caloric needs (descriptive name of scale) calorie needs met. |  | Daily up to 7 days of ICU stay | 
| Percentage of daily caloric needs met (%) calorie needs met. |  | Daily up to 7 days of ICU stay | 
| Estimated protein needs (grams protein/day) |  | Daily up to 7 days of ICU stay | 
| Method for estimating protein needs (descriptive name of scale) |  | Daily up to 7 days of ICU stay | 
| Percentage of daily protein needs met (%) |  | Daily up to 7 days of ICU stay | 
| Laboratory values (Blood Urea Nitrogen) |  | Daily up to 7 days of ICU stay | 
| Laboratory values (Creatinine) |  | Daily up to 7 days of ICU stay | 
| Laboratory values (Aspartate aminotransferase) |  | Daily up to 7 days of ICU stay | 
| Laboratory values (Alanine transaminase) |  | Daily up to 7 days of ICU stay | 
| Laboratory values (Glucose) |  | Daily up to 7 days of ICU stay | 
| Laboratory values (Ammonia) |  | Daily up to 7 days of ICU stay | 
| Gastrointestinal side effects observed in enterally fed patients in the ICU |  | Daily up to 7 days of ICU stay | 
| Insulin use |  | Daily dose up to 7 days of ICU stay | 
| Health Outcomes (Renal failure, Seizures, Encephalopathy, Hyperglycemia, Hypoglycemia) |  | Daily up to 7 days of ICU stay | 
| Utilization of renal replacement therapy (Yes/No) |  | Daily up to 7 days of ICU stay | 
| Utilization of medications to manage hepatic encephalopathy (lactulose) (Yes/No) |  | Daily up to 7 days of ICU stay | 
| Neurocognitive status (Glasgow Coma Scale) |  | Daily up to 7 days of ICU stay | 
| Presence of delirium (Yes/No) |  | Daily up to 7 days of ICU stay | 
| ICU Length of Stay |  | Up to 90 Days | 
| Hospital Length of Stay |  | Up to 90 Days | 
| Ventilator days |  | Up to 90 Days | 
| Antibiotic therapy days |  | Up to 90 Days | 
| 30 day readmission |  | Incidence up to 30 days post discharge | 
| Death during hospitalization (Yes/No) |  | Through study completion, assessed an estimated 36 months | 
| Destination for discharge (home, another acute care hospital, Long Term Acute Care, rehabilitation center, nursing home) | Destination of Discharge will be assessed via chart review. | Through study completion, assessed an estimated 36 months | 
| Discharge against medical advice (Yes/No) |  | Through study completion, assessed an estimated 36 months |