Laparoscopic Gas Pressure and Postoperative Pain Score

Study Overview
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Brief Summary
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Aim of the study is to determine the effect of different laparoscopic intraoperative intraabdominal gas (CO2) pressures on the extent of postoperative pain scores.

Detailed Description
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In this study investigator planned to randomize patients into three groups ; in the first group abdominal entrance pressure will be 15 mmhg and intraoperative pressure will be 15 mmhg too ; in the second group again entrance pressure will be 15 mmhg , intraoperative pressure will be 12 mmhg ; and in the thirth group both entrance and intraoperative pressures will be 12 mmhg. During operation intraoperative mean pressures will be recorded every 15 minutes , also end tidal CO2 pressures will also assesed by the anesthesiologist. Every participant will take , same standard analgesics ; 2 mg/kg contramal and 1 gr i.v. paracetamol at the end of the operation ; except the ones who has allergy to these analgesics. At postoperative 6 th and 24 th hours patients will be asked to execute the visual analogue score (VAS) form to assess the pain . Only patients with benign gynecologic pathologies will be included in to the study and informed consent forms will be taken from all participants.

Official Title
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Does Laparoscopic Entrance and Intraoperative Intraabdominal Gas Pressure Effect Postoperative Pain Score

Conditions
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Postoperative Pain, Laparoscopy

Intervention / Treatment
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* Procedure: low gas pressure laparoscopy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: benign gynecologic pathologies which requires laparoscopic surgery Exclusion Criteria: patients who has malign gynecologic pathologies
Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: 15 mmhg-15mmhg<br>Abdominal entrance pressure will be set to 15 mmhg , after laparoscopic visualization of abdomen ; maintenance pressure will be set to 15 mmhg. | |
| Other: 15 mmhg-12 mmhg<br>Abdominal entrance pressure will be set to 15 mmhg , after laparoscopic visualization of abdomen ; maintenance pressure will be set to 12 mmhg. Low gas pressure laparoscopy | Procedure: low gas pressure laparoscopy<br>* To apply different CO2 entrance and intraoperative pressures<br>|
| Other: 12 mmhg-12 mmhg<br>Abdominal entrance pressure will be set to 12 mmhg , after laparoscopic visualization of abdomen ; maintenance pressure will be set to 12 mmhg. Low gas pressure laparoscopy | Procedure: low gas pressure laparoscopy<br>* To apply different CO2 entrance and intraoperative pressures<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| postoperative pain scores | Difference between pain scores of participitants according to differing gas pressures applied. | Postoperative 6 th hour | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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postoperative pain, Intraabdominal laparoscopic gas pressure