linjc16/ctgov huggingface dataset:
Usefulness of Chromoendoscopy in Diagnosing Microscopic Colitis

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to determine whether chromoendoscopy using Indigo-Carmine dye spray is useful in diagnosing microscopic colitis among patients undergoing colonoscopy due to chronic watery diarrhea.

Detailed Description
-----------------
Microscopic colitis is a common disease found in 10% to 20% of cases having chronic watery diarrhea. Obvious endoscopically identifiable changes of the mucosal surface are usually absent, thus diagnosing microscopic colitis relies on multiple biopsy sampling from all segments of the colon. Chromoendoscopy using indigo-carmine dye spray might, however, unravel mucosal changes in microscopic colitis (Suzuki 2011). The aim of this study is to investigate if chromoendoscopy using Indigo-Carmine 0.2-0.5% in patients with chronic watery diarrhea is useful in diagnosing microscopic colitis.

Official Title
-----------------
Prospective Study on the Usefulness of Chromoendoscopy in Detecting Microscopic Colitis in Patients Undergoing Colonoscopy Due to Chronic Watery Diarrhoea

Conditions
-----------------
Chronic Diarrhoea, Lymphocytic Colitis, Collagenous Colitis

Intervention / Treatment
-----------------
* Procedure: Colonoscopy with Indigo-Carmine Chromoendoscopy


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with chronic non-bloody diarrhea for at least one month Exclusion Criteria: Patients who decline to participate Unable to give informed consent

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Chromoendoscopy<br> | Procedure: Colonoscopy with Indigo-Carmine Chromoendoscopy<br>* Colonoscopy with chromoendoscopy using 0.2-0.5% Indigo-Carmine solution sprayed in five areas of the large intestine: Cecum, ascending colon, transverse colon, descending colon and rectum. Pictures are taken before and after dye-spraying and biopsies are collected from all segments of the large intestine and rectum.<br>* Other names: Indigo-Carmine;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Detection of microscopic colitis using chromoendoscopy | To investigate the usefullness of chromoendoscopy in diagnosing microscopic colitis using 0.2-0.5% Indigo-Carmine dye spray. The golden standard is the results of histological examination of biopsies from the colo-rectal mucosa. | 12 month | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Microscopic colitis, Intestinal Diseases, Inflammatory Bowel Diseases
Using Near Infra-red Spectroscopy to Measure Tissue Perfusion in Patients Receiving Coronary Artery Bypass Graft Surgery

Study Overview
=================
Brief Summary
-----------------
Near infra-red spectroscopy (NIRS) was used to measure the tissue perfusion of the cerebral cortex with two noninvasive adhesive patches in recent years. This study is designed to compare the regional tissue perfusion of different body areas in patients receiving coronary artery bypass surgery under general anesthesia. The NIRS data will also be used to compare with other routine physiological monitors in the surgery.

Detailed Description
-----------------
Study Design: Prospective observational study Target Number of Participants: To recruit 50 patients into this study. Patient Selection: Patients scheduled for elective coronary artery bypass surgery. The American Society of Anesthesiologists physical status classification system(ASA) Class I III Age ≧20 y/o, ≦75 y/o Exclusion Criteria: ASA Class IV Current skin lesion over the sites where the NIRS patches are designed to be attached. Patients received cardiopulmonary bypass during the surgery. Patients with previous history of allergy to the NIRS patches. Study Method: After the induction of anesthesia, four NIRS patches are attached to the patients on the following sites: Biceps brachii muscle area Gastrocnemius muscle area Posterior side of neck central part of the forehead The four non-invasive NIRS patches are only to measure the tissue oxygen saturation and have no other physiological effects on the participants. The data will be collected every 5 minutes until the surgery is completed. The data from other routine monitors used during the surgery (including hear rate, blood pressure, and mixed venous saturation) will also be used to compare with the data from NIRS.

Official Title
-----------------
Using Non-invasive Near Infra-red Spectroscopy to Measure the Regional Tissue Perfusion in Patients Receiving Off-pump Coronary Artery Bypass Graft Surgery

Conditions
-----------------
Coronary Artery Disease

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age ≧20 years old, ≦75 years old Patients scheduled for elective coronary artery bypass surgery ASA Class I III Exclusion Criteria: Patients scheduled for cardiopulmonary bypass Allergy for NIRS

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Percentage of tissue oxygen saturation (StO2) | The measured tissue oxygen saturation is shown in the form of percentage (0 100%). | every 5 minute, from the induction of anesthesia to the end of the surgery, estimated duration: 4 hours | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
near infra-red spectroscopy, coronary artery bypass grafting
Efficacy and Safety of Levocetirizine Versus Loratadine for the Treatment of Perennial Allergic Rhinitis

Study Overview
=================
Brief Summary
-----------------
Efficacy and Safety of Levocetirizine Versus Loratadine for the Treatment of Perennial Allergic Rhinitis.

Official Title
-----------------
A Study Evaluating the Efficacy and Safety of 5 mg Levocetirizine Oral Tablets, Once Daily Versus 10 mg Loratadine Oral Tablets, Once Daily for the Treatment of Perennial Allergic Rhinitis.

Conditions
-----------------
Rhinitis, Allergic, Perennial

Intervention / Treatment
-----------------
* Drug: levocetirizine dihydrochloride


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Male ore female, 16 to 60 years old (inclusive) two-year history of allergic rhinitis due to house dust mite Exclusion Criteria: An ear, nose or throat (ENT) infection asthma requiring daily drug therapy other than ß2 inhaled agonists taken prn atopic dermatitis or urticaria requiring an antihistamine or corticosteroid treatment an associated ENT disease use of decongestants nasal or ocular topical treatment desensitivation

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 60 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: levocetirizine dihydrochloride|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Total 5 Symptom Score (T5SS) rated by the investigator |  | 2 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Investigators global efficacy evaluation at the end of treatment; subject's rating of T5SS and individual symptoms (over the last 24 hours) over first week and the total 2 weeks treatment period; the Symptoms Score Reducing Index (SSRI). |  | 2 weeks | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
levocetirizine dihydrochloride, Xyzal tablets
Valsalva Maneuver and Control in Reducing Pain During Spinal Injection

Study Overview
=================
Brief Summary
-----------------
The study aimed to compare the effectiveness of Valsalva maneuver as non pharmacological approach and control in reducing pain during spinal injection.

Detailed Description
-----------------
This was an experimental study on 70 subjects with 35 subjects treated with Valsalva maneuver and 35 subjects treated as control from January to April 2019. Research subjects were female who underwent brachytherapy for the first time with spinal anesthesia. The effectiveness in reducing pain was assessed by using Visual Analogue Scale (VAS) and patient movement during the surgery.

Official Title
-----------------
Comparison of Valsalva Maneuver and Control in Reducing Pain During Spinal Injection

Conditions
-----------------
Brachytherapy

Intervention / Treatment
-----------------
* Other: Valsalva maneuver
* Other: Control


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients underwent elective surgery using spinal anesthesia patients who have not undergone spinal anesthesia before Physical status ASA I or II Signing informed consent Exclusion Criteria: have a spinal anesthesia history contraindicated for spinal anesthesia subjects who cannot do Valsalva to 30mmHg pressure for 20 seconds have a allergic history to local anesthetics or opioid drugs

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Valsalva Maneuver<br>Patient will do valsalva maneuver for 20 seconds | Other: Valsalva maneuver<br>* pressure during Valsalva maneuver was measure using sphygmomanometer<br>|
| Placebo Comparator: control<br>Patient will do nothing | Other: Control<br>* patient was not given any intervention<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain measurement during injection with VAS score | Pain degree was measured with VAS score [0 equals to no pain whereas 10 equals to the maximum pain] | 30 seconds | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Patient movement | Investigator observes patient movement during the first spinal injection | 30 seconds | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
valsalva maneuver, control, pain, spinal injection
The Epidemiology of TST Change in Korea

Study Overview
=================
Brief Summary
-----------------
TST will be analyzed in young general population in Korea. Young adults undertake TST as CDC recommendation. Participants with chest radiograph showing active TB lesion are excluded from this study.

Detailed Description
-----------------
Enroll criteria A term of whole military conscripts per year in one Reserve Force Battalion Military conscripts gather from all around area in Korea randomly Each participant undertake a chest X-ray (CXR) and blood tests including human immunodeficiency virus (HIV) at the start of initiatory training. Exclusion Criteria Chest X-ray suggesting active TB HIV positive in serology Design After giving informed consent, all participants receive one-step TST following standard procedures. The largest transverse diameter of induration is measured 48-72hr after injection. The investigator and these trained nurses were blinded to the status of their demographic characteristics.

Official Title
-----------------
The Trend of Tuberculin Skin Test in Korea

Conditions
-----------------
Tuberculosis, Latent Tuberculosis

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Military Conscripts age 18-29 years old Exclusion Criteria: Chest X-ray suggests active TB Positive HIV in serology

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 29 Years

Sexes Eligible for Study
-----------------
Male

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Military Conscripts<br>A term of whole military conscripts per year in one Reserve Force Battalion. Military conscripts gather from all around area in Korea randomly | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| TST positivity TST rate | Investigators measure induration size of tuberculin skin test 48 after tuberculin injection. | Two days after tuberculin injection | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| BCG scar rates |  | The day of tuberculin injection |
The TransEnterix European Patient Registry

Study Overview
=================
Brief Summary
-----------------
An open label observational registry trial in which participating centers enroll subjects who had or will have a laparoscopically assisted surgery using the Senhance Surgical System.

Detailed Description
-----------------
This is a prospective multi-center registry in which sites may also choose to retrospectively enroll subjects meeting the inclusion criteria, but whom have already been treated using the Senhance system. The data collection includes baseline patient characteristics, surgical details, and adverse events. Patient follow-up time point is open to the clinical practice of each center and only adverse events are tracked post discharge.

Official Title
-----------------
The TransEnterix European Patient Registry for Robotic Assisted Laparoscopic Procedures in Urology, Abdominal Surgery, Thoracic and Gynecologic Surgery

Conditions
-----------------
Surgery

Intervention / Treatment
-----------------
* Device: Surgery


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients 18-80 years old Signed the informed consent life expectancy 12 months or more Exclusion Criteria: -

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Senhance Treated<br>All patients enrolled who go on to have a surgery in which the Senhance system is used | Device: Surgery<br>* Patients are approached surgically with the Senhance Surgical System<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Adverse Event | Any untoward sign symptom or disease | Surgery to 30 days post op | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Robotic, Laparoscopic
Effects of Home Visits on Medication Adherence in Children and Youth With HIV

Study Overview
=================
Brief Summary
-----------------
Adherence to complex medication regimens is critical to successful treatment of HIV infection. Unfortunately, adherence to medical regimens with conventional interventions averages 50% in chronic disease. We have observed that adherence barriers that were unrecognized by providers in the clinic setting have been detected during home visits. It is possible that recognition and interventions to resolve adherence barriers observed during home visits may improve adherence. This proposal will test the hypothesis that home-visits which identify previously unrecognized adherence barriers and provide support and education will increase medication adherence among children and youth with HIV infection and improve the patient/health care provider relationship. Specific aims of the study are: 1. Determine the impact of a series of home-visits on adherence to medication regimens for HIV infected youth and children. 1a. Adherence to medical regimens will be assessed before and after the series of home-visits using a self-report questionnaire and Microelectronic Monitoring System (MEMS) or in-home pill count. 1b. For each of these measures a percentage of adherence will be calculated and compared from a baseline to after the final home visit and after the six month follow up period. 2. Assess the changes in patient satisfaction from baseline to after the home-visits using a questionnaire completed by the patient/family. 3. Incorporate a pilot study to assess the changes in the provider's knowledge of the patient's family characteristics and home circumstances relevant to adherence following the home visits.

Conditions
-----------------
HIV Infections

Intervention / Treatment
-----------------
* Behavioral: Counseling in the home


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: HIV positive English speaking Live in Denver metro area Taking >=1 antiretroviral medication

Ages Eligible for Study
-----------------
Minimum Age: 0 Years
Maximum Age: 24 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Educational/Counseling/Training
Intervention Model: Single Group Assignment


Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: Counseling in the home|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
HIV
Home-Based Dual-Task Training for Older Adults

Study Overview
=================
Brief Summary
-----------------
This project is focused on conducting a home-based, thinking while moving exercise intervention for adults 65 years or older, who have mild cognitive impairment, that will integrate several effective training modalities including non-contact cardio-kickboxing, stepping exercise, balance/functional training, and muscle strengthening. Cognitive function, physical function, and dual-task abilities will be assessed over the 12-week intervention and comparisons will be made between participants in the exercise intervention and control participants receiving no intervention.

Official Title
-----------------
Home-Based Dual-Task Training to Improve Function in Older Adults

Conditions
-----------------
Mild Cognitive Impairment

Intervention / Treatment
-----------------
* Behavioral: Dual-Task Exercise Training


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 65 years or older Male or female Screened positive for mild cognitive impairment (Montreal Cognitive Assessment score 23 to 26 points Having no absolute contraindications to non-physician supervised exercise. Exclusion Criteria: Lower-body amputation Non-English language speaker

Ages Eligible for Study
-----------------
Minimum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Dual-Task Training<br> | Behavioral: Dual-Task Exercise Training<br>* Simultaneous cognitive-motor training<br>|
| No Intervention: Control<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Cognitive Function (Interference inhibition and attention) | Change in performance on the Stroop Color-Word Interference Test | baseline, 6 week, 12 weeks | 
| Change in Cognitive Function (Task-switching and attention) | Change in performance on the Trail-Making Test Sections A and B | baseline, 6 week, 12 weeks | 
| Change in Walking Ability, Lower-Body Strength, and Balance | Change in performance on the Short Physical Performance Battery | baseline, 6 weeks, 12 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Dual-Task Performance | Change in the Timed Up and Go Test: Dual Task (single condition, motor condition, and cognitive condition | baseline, 6 week, 12 weeks |