Observe Real-life Allocation of Atypical Antipsychotics in the Acute Inpatient Management of Schizophrenia

Study Overview
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Brief Summary
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The primary objective of this Non- Interventional Study (NIS) is to describe the use of atypical antipsychotics in subjects with Schizophrenia during the hospitalisation due to acute psychotic episode by evaluation of drug, dose and mode of administration of the medication.

Detailed Description
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RECONNECT-S BETA

Official Title
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A Non- Interventional Study to Observe Real Life Usage of Atypical Antipsychotics in the Acute Inpatient Management of Schizophrenia.

Conditions
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Schizophrenia

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Meet the diagnostic criteria for schizophrenia stated in The Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) criteria. Subject is hospitalised due to an acute psychotic episode. Ability of the subject to understand and comply with the requirements of the study, as judged by the investigator. Exclusion Criteria: Current participation in any clinical trial. Previous enrolment in the present NIS (in case of recurrence occurred during the enrolment period).

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Subjects who are hospitalized due to acute psychotic episode.<br>All subjects who are hospitalized due to acute psychotic episode. The subjects should be managed according to normal clinical practice until discharge time. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Use of atypical antipsychotic(s) during hospitalisation. | The data will be collected at one visit at the moment of discharge from the hospital. | Hospitalisation period, an expected average of 3 weeks (variable per patient). | 
| Daily dosage of atypical antipsychotic(s) during hospitalisation. | The data will be collected at one visit at the moment of discharge from the hospital. | Hospitalisation period, an expected average of 3 weeks (variable per patient). | 
| Mode of administration of atypical antipsychotic(s) during hospitalisation. | The data will be collected at one visit at the moment of discharge from the hospital. | Hospitalisation period, an expected average of 3 weeks (variable per patient). | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Percent of patients with atypical antipsychotic as monotherapy. | The data will be collected at one visit at the moment of discharge from the hospital. | Hospitalisation period, an expected average of 3 weeks (variable per patient). | 
| Percent of patients with combinations of antipsychotics. | The data will be collected at one visit at the moment of discharge from the hospital. | Hospitalisation period, an expected average of 3 weeks (variable per patient). | 
| Main criteria of an antipsychotic's selection during hospitalisation expressed as percentage. | The data will be collected at one visit at the moment of discharge from the hospital. | Hospitalisation period, an expected average of 3 weeks (variable per patient). | 
| Use of psychometric scales in day to day practice in therm of evaluation of the disease symptoms and thus efficacy of the treatment. | The data will be collected at one visit at the moment of discharge from the hospital. | Hospitalisation period, an expected average of 3 weeks (variable per patient). | 
| Description of the usage of concomitant psychiatric medication (other than atypical antipsychotic) during the hospitalization. | The data will be collected at one visit at the moment of discharge from the hospital. | Hospitalisation period, an expected average of 3 weeks (variable per patient). | 
| Relationship between medication used during the hospitalization and maintenance therapy recommended upon discharge. | The data will be collected at one visit at the moment of discharge from the hospital. | Hospitalisation period, an expected average of 3 weeks (variable per patient). | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Acute psychotic episode of Schizophrenia