Therapeutic Exercise and Education in Pain Neurophysiology to Improve Pain Intensity in Women With Endometriosis. Clinical Trial.

Study Overview
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Brief Summary
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The objective of this study will be to evaluate treatment using ET exercise and pain education in women with endometriosis to improve pain intensity.

Detailed Description
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A study will be carried out whose objective is to improve the intensity of pain in women with endometriosis through a program of therapeutic exercise and education in the neurophysiology of pain. Also as secondary variables will be observed: kinesiophobia, catastrophism and impression of global improvement with treatment.

Official Title
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Therapeutic Exercise and Education in Pain Neurophysiology to Improve Pain Intensity in Women With Endometriosis. Clinical Trial.

Conditions
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Endometriosis

Intervention / Treatment
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* Other: Therapeutic exercise AND pain neurophysiology education
* Other: Sham


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Women of reproductive age between 18 and 45 years. Women with a medical diagnosis of endometriosis. Women with visual analog scale (EVA) between 4 and 10 (moderate-severe pain) during the last 3 months in the suprapubic area, abdomen or perineum both continuously and intermittently. Exclusion Criteria: Women who must have surgery during the study. Women who have undergone abdominal or pelvic surgery or who have given birth (vaginal or cesarean) in the last 6 months. Women who are pregnant or planning a pregnancy. Women with uncorrected pacemakers or coagulopathies, severe comorbid disorder, cancer (in the last 5 years or at present), severe mental disorders, or neuropathies affecting the nerves of the pelvis or lower extremities. Physiotherapy treatments or treatments related to pathology or study areas 15 days prior to the beginning of the study. Variations in medication in the 3 months prior to the start of the study.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Through a randomization program, participants will be assigned to the treatment group or the control group.
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Therapeutic Exercise AND Pain Neurophysiology Education<br>Therapeutic exercise: Therapeutic exercise is the systematic and planned execution of posture movements and physical activities to correct or prevent alterations, improve or enhance physical functioning, prevent risk factors for solid and optimize overall health status. Pain Neurophysiology Education: Education in pain neurophysiology consists in describing to the patient the neurobiology and neurophysiology of his nervous system pain to improve the processing of it and diminish the threatening meaning of pain. | Other: Therapeutic exercise AND pain neurophysiology education<br>* A program of therapeutic exercise and education in the neurophysiology of pain will be applied to the participants of the experimental group and talks on healthy habits to the placebo group participants.<br>|
| Sham Comparator: Sham Comparator<br>Talks about healthy habits | Other: Sham<br>* Talk about healthy habits<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes in pain perception assessed using a 100mm Visual Analogue Scale (VAS) | The scale will be administered by one of the researchers. Minimum value 0. Maximum value 100. Higher score = Higher level of pain. Lowe and lower scores mean a better result. | Baseline, Up to 1 month, Up to 3 months, Up yo 6 months. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes in Kinesiofobia assessed using the Tampa Scale of Kinesiofobia (TSK) | The scale will be administered by one of the researchers. Minimum value 11. Maximum value 44. Higher score = Higher level of kinesiophobia. Lower and lower scores mean better results. | Baseline, Up to 1 month, Up to 3 months, Up to 6 months. | 
| Changes in Catastrophism assesed using the Pain Catastrophism Scale (PCS) | The scale will be administered by one of the researchers. Minimum value 0. Maximum value 52. Higher score = Higher level of catastrophism. Lower and lower scores mean better results. | Baseline, Up to 1 month, Up to 3 months, Up to 6 months. | 
| Impression of the overall improvement obtained with the treatment ussing the Global rating of changes scale (GROC) | The scale will be administered by one of the researchers. Minimum value -7. Maximum value 7. Higher score = Increased improvement with treatment. Lower scores = 45 / 5.000 Resultados de traducción Resultado de traducción worsening of the patient with treatment. | Up to 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Pain, Quality of life, Chronic pelvic pain, therapeutic exercise, pain neurophysiology, physiotherapy