Evaluation of Short-term Effects of Tourniquet Use in Different Ways During Total Knee Arthroplasty

Study Overview
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Brief Summary
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To study the short-term effects of tourniquet use in different ways in total knee arthroplasty,60 patients were randomly divided into 2 groups (30 cases/group): group A using the tourniquet throughout the operation, and group B using the tourniquet starting from the implantation of prosthesis to the completion of the operation. Operation time, total measured blood loss, intraoperative transfusion volume, and complication were recorded. Hemoglobin level was recorded preoperatively and in postoperative 1, 3, 7 and 14 days, and the limb circumference, pain score, and knee joint range of motion were also recorded preoperatively and in postoperative 3,7 and 14 days.Investigators want to observe the difference between the two groups. Hypothesis was made that patients in group B may feel better after operation for short time use of tourniquet.

Detailed Description
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Objective: To study the short-term effects of tourniquet use in different ways in total knee arthroplasty. Methods: 60 patients were randomly divided into 2 groups (30 cases/group): group A using the tourniquet throughout the operation, and group B using the tourniquet starting from the implantation of prosthesis to the completion of the operation. Operation time, total measured blood loss, intraoperative transfusion volume, and complication were recorded. Hemoglobin level was recorded preoperatively and in postoperative 1, 3, 7 and 14 days, and the limb circumference, pain score, and knee joint range of motion were also recorded preoperatively and in postoperative 3,7 and 14 days.

Official Title
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Evaluation of Short-term Effects of Tourniquet Use in Different Ways During Total Knee Arthroplasty: a Randomized Controlled Trial

Conditions
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Osteoarthritis

Intervention / Treatment
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* Procedure: short time tourniquet


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients eligible for the study included those who underwent initial unilateral TKA for osteoarthritis or rheumatoid arthritis. Exclusion Criteria: Patients with diabetes, hemorrhagic disease, Hb < 100 g/L, peripheral neurovascular disease, malignant tumors, history of vascular thrombosis, or history of infection in the lower limb were excluded
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| short time tourniquet<br>60 patients were randomly divided into 2 groups (30 cases/group): group A using the tourniquet throughout the operation, and group B using the tourniquet starting from the implantation of prosthesis to the completion of the operation(short time). | Procedure: short time tourniquet<br>* short time tourniquet: the tourniquet starting from the implantation of prosthesis to the completion of the operation.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the limb circumference at 10 cm above the knee at postoperative day 1,3,7 and 14 |  | 14 days after the surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Limb swelling, Limb circumference, Tourniquet, Total knee arthroplasty, Blood loss