Potato Consumption and Energy Balance

Study Overview
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Brief Summary
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A randomized, clinical trial will be performed to assess changes in body weight and fat mass with daily potato consumption versus a calorie-matched snack of almonds.

Detailed Description
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This is a 30-day randomized, controlled trial with 3 arms: 1) non-potato food (almonds), 2) standard white potato French fry, 3) standard white potato French fry with potential glycemia-modulating spice/seasoning mix added. Free-living study participants will be assigned to consume one of the 3 foods (calorie matched) each day for a 30-day period. Body composition (via dual energy x-ray absorptiometry; DXA), and blood chemistry will be assayed at baseline and study completion, along with a sub-sample of subjects participating in a meal-based tolerance tests at study completion.

Official Title
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Potato Consumption and Energy Balance: a Randomized, Controlled, Clinical Trial

Conditions
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Obesity

Intervention / Treatment
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* Other: White potato (french fries)
* Other: White potato (French fries), +seasoning
* Other: Almond


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 18- 50 years old Body mass index (BMI) 20- 35 No dietary restrictions or allergies Weight stable Access to camera through smartphone, computer or tablet Exclusion Criteria: Pregnancy or anticipating pregnancy or lactation Nut or food allergy Diagnosed diabetes (Type 1 or 2) History of weight control surgery (bariatric or liposuction) Consumes >1 serving of potatoes daily before enrollment Weight loss or gain >5% within past 6 months Medical conditions or medications that would prevent the ability to comply with treatment assignment and/or affect energy balance Dependence on others for food procurement or preparation

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: White potato (French fries)<br>Participants will be asked to consume 1 serving of French fries each day for 30 days. | Other: White potato (french fries)<br>* If randomized to this group, participants will be asked to consume 1 serving of French fries ( 300 kcal) each day for 30 days as a part of their usual dietary intake. French fries will be portioned and provided to participants.<br>|
| Experimental: White potato (French fries), +seasoning<br>Participants will be asked to consume 1 serving of French fries with added seasoning each day for 30 days. | Other: White potato (French fries), +seasoning<br>* If randomized to this group, participants will be asked to consume 1 serving of French fries ( 300 kcal) with added potential glycemia modifying seasoning mix each day for 30 days as a part of their usual dietary intake. French fries and seasoning will be portioned and provided to participants.<br>|
| Active Comparator: Almond<br>Participants will be asked to consume 1 serving of almonds (calorie-matched to other arms) day for 30 days. | Other: Almond<br>* If randomized to this group, participants will be asked to consume 1 serving of almonds that is calorically-matched to the French fries ( 300 kcal) serving in the other arms each day for 30 days as a part of their usual dietary intake. Almonds will be portioned and provided to participants.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in fat mass | Determined by dual-energy X-ray absorptiometry. | baseline and study completion (30 days) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in body weight |  | baseline and study completion (30 day) | 
| Change in fasting glucose |  | baseline and study completion (30 day) | 
| Change in fasting insulin |  | baseline and study completion (30 day) | 
| Change in HbA1c |  | baseline and study completion (30 day) | 
| Change in caloric Intake | Dietary recall by 3 day food record. | baseline and study completion (30 days) | 
| Meal Tolerance Test | A subset of subjects from each diet group will participate in a meal-based tolerance test with the study food items. | Study Completion (30 day) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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nutrition intervention, potato consumption, energy balance