USI and/or DO in Women With Cystocele Before and After Cystocele Repair

Study Overview
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Brief Summary
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The changes of lower urinary tract function after cystocele repair are important for perioperative consultation and management. Thus, the aim of this retrospective study was to evaluate the prevalence of urodynamic stress incontinence and/or detrusor overactivity in women with ≥ stage II cystocele and the changes of incontinence function after cystocele repair.

Detailed Description
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Between November 2010 and October 2020, all women with ≥ stage II cystocele who visited the urogynecological department of a medical center for cystocele repair were reviewed. Those women who had complete data of preoperative and postoperative 3-month follow-up urodynamic data were excluded from this study. Urodynamic stress incontinence was diagnosed by the finding of involuntary leakage during filling cystometry or stress urethral pressure profile, associated with increased intra-abdominal pressure, in the absence of a detrusor contraction. Detrusor overactivity was defined as the occurrence of involuntary detrusor contractions during filling cytometry. STATA software was used for statistical analysis. Chi2 test, univariate and multivariable logistic regression tests were used for statistical analysis as appropriate. A p < 0.05 was considered as statistically significant.

Official Title
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Prevalence of Urodynamic Stress Incontinence and/or Detrusor Overactivity in Women With Cystocele and the Changes of Continence Function After Cystocele Repair

Conditions
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Urodynamic Stress Incontinence, Detrusor Overactivity

Intervention / Treatment
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* Procedure: Cystocele repair


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Women with ≥ stage II cystocele Received cystocele repair Complete urodynamic study before and after surgery Exclusion Criteria: Incomplete data Chronic infection Recurrent surgery for cystocele

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Women with cystocele<br>All women with ≥ stage II cystocele who visited the urogynecological department of a medical center for cystocele repair | Procedure: Cystocele repair<br>* Fascial repair for endopelvic fascia and anterior colporrhaphy<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Urodynamic stress incontinence | the finding of involuntary leakage during filling cystometry or stress urethral pressure profile, associated with increased intra-abdominal pressure, in the absence of a detrusor contraction | November 2010 and October 2020 | 
| Detrusor overactivity | the occurrence of involuntary detrusor contractions during filling cytometry | November 2010 and October 2020 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Urodynamic stress incontinence, Detrusor Overactivity, Cystocele