Use of White Granulated Sugar on Wounds

Study Overview
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Brief Summary
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How effective is sugar in reducing the debriding of sloughy, necrotic or infected exudating wounds compared with standard treatment?

Detailed Description
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Patients for whom all the following apply: Have an exudating wound sizes 5cm2 and 40cm2 A minimum of 25% slough, infected and necrotic tissue No dry necrotic eschar present Ankle Brachial Pressure Index of greater than 0.6 Are over 18 years Independently and willingly consent

Official Title
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A Randomised Controlled Trial to Investigate the Clinical and Cost-effectiveness of White Granulated Sugar Dressing Compared With Standard Treatment in the Management of Exudating Wounds With Parallel Economic Evaluation

Conditions
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Infected Wounds

Intervention / Treatment
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* Other: Granulated Sugar
* Other: Debridement Dressing


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Exudating wound sizes 5cm2 and 40cm2 A minimum of 25% slough, infected and necrotic tissue No dry necrotic eschar Ankle Brachial Pressure Index of greater than 0.6 Age over 18 years Able to independently and willingly consent Exclusion Criteria: Participants in a trial evaluating other therapies for their wound Have previously been in this trial Women who are pregnant Participants not able to tolerate daily dressing change

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Chronic & Acute infected wounds<br>Wound will be cleaned with normal saline or tap water and Granulated sugar will be applied directly to the wound and covered with an absorbent pad and held in place with a bandage and tape. | Other: Granulated Sugar<br>* 30 grams of granulated sugar is used to cover the wound area and this is held in place using a dry dressing pad , bandage and tape.<br>* Other names: Sucrose;Other: Debridement Dressing<br>* 1 Aquacel or Sorbsan dressing will be put over the wound, and held in place with a dry dressing pad, bandage and tape.<br>* Other names: Aquacel or Sorbsan;|
| Active Comparator: Chronic and Acute infected wounds<br>Wound will be cleaned with normal saline or tap water and an appropriate debridement dressing (Aquacel or Sorbsan) is applied to the wound and secured with a bandage and surgical tape. | Other: Granulated Sugar<br>* 30 grams of granulated sugar is used to cover the wound area and this is held in place using a dry dressing pad , bandage and tape.<br>* Other names: Sucrose;Other: Debridement Dressing<br>* 1 Aquacel or Sorbsan dressing will be put over the wound, and held in place with a dry dressing pad, bandage and tape.<br>* Other names: Aquacel or Sorbsan;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Time to debridement of wound | wounds will be photographed at entry into the study there after weekly till end of study at 4 weeks | 4 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Reduction in wound surface area | Wound measurements will be taken at entry into the study then weekly until end of 4 weeks | 4 weeks |