Study Inflammation During a 100 Miles

Study Overview
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Brief Summary
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To study per and post effort variations of inflammatory biological markers during a 100 miles

Official Title
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Per Effort Study of Inflammation During a 100 Miles

Conditions
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Inflammatory Response

Intervention / Treatment
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* Other: Blood sample


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: adults (age>18years) completion of an ultra endurance race (50 miles) during the 2 years before Exclusion Criteria: female age<18years

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Blood sample|Blood sample to study per and post effort evolution markers of systemic inflammation|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Variation per and post effort of interleukin 1 plasma level | Plasma level of per and post effort of interleukin 1 will be measured | Change measures : departure, 25, 49, 72, 100, 126, 144, 164 kilometers (arrival) then at day 1, day 2 and day 7 after the completion of the race | 
| Variation per and post effort of interleukin 6 plasma level | Plasma level of per and post effort of interleukin 6 will be measured | Change measures : departure, 25, 49, 72, 100, 126, 144, 164 kilometers (arrival) then at day 1, day 2 and day 7 after the completion of the race | 
| Variation of per and post effort of protein C reactive | Plasma level of per and post effort of protein C reactive will be measured | Change measures : departure, 25, 49, 72, 100, 126, 144, 164 kilometers (arrival) then at day 1, day 2 and day 7 after the completion of the race | 
| Variation per and post effort of interleukin Tumor Necrosis Factor alpha | Plasma level of per and post effort of tumor necrosis alpha will be measured | Change measures : departure, 25, 49, 72, 100, 126, 144, 164 kilometers (arrival) then at day 1, day 2 and day 7 after the completion of the race | 
| Variation per and post effort of interleukin 4 plasma level | Plasma level of per and post effort of interleukin 4 will be measured | Change measures : departure, 25, 49, 72, 100, 126, 144, 164 kilometers (arrival) then at day 1, day 2 and day 7 after the completion of the race | 
| Variation per and post effort of interleukin 10 plasma level | Plasma level of per and post effort of interleukin 10 will be measured | Change measures : departure, 25, 49, 72, 100, 126, 144, 164 kilometers (arrival) then at day 1, day 2 and day 7 after the completion of the race | 
| Variation per and post effort of interleukin 13 plasma level | Plasma level of per and post effort of interleukin 13 will be measured | Change measures : departure, 25, 49, 72, 100, 126, 144, 164 kilometers (arrival) then at day 1, day 2 and day 7 after the completion of the race | 
| Variation per and post effort of interleukin tumor growth factor beta plasma level | Plasma level of per and post effort of tumor growth factor beta | Change measures : departure, 25, 49, 72, 100, 126, 144, 164 kilometers (arrival) then at day 1, day 2 and day 7 after the completion of the race | 
| Variation per and post effort of lipids plasma level | Plasma level of per and post effort of lipids | Change measures : departure, 25, 49, 72, 100, 126, 144, 164 kilometers (arrival) then at day 1, day 2 and day 7 after the completion of the race | 
| Variation per and post effort of lipoproteins plasma level | Plasma level of per and post effort of lipoproteins | Change measures : departure, 25, 49, 72, 100, 126, 144, 164 kilometers (arrival) then at day 1, day 2 and day 7 after the completion of the race | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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sport exercise, ultra endurance