Periprosthetic Fracture Registry (PPFx)

Study Overview
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Brief Summary
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This registry supports international data collection and research on PPFx treatments after hip and knee arthroplasty. A registry such as this ultimately aims to provide far-reaching benefits to society including reduced morbidity and mortality, improved patient safety, improved quality of care and medical decision-making, reduced medical spending, and advances in orthopaedic science.

Detailed Description
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To close the gap of missing clinical evidence regarding the treatment of periprosthetic fractures after arthroplasty of the hip or the knee with osteosynthesis. To drive further study hypotheses and to answer unforeseen questions. Main questions to be answered by the registry include (but are not exclusive) the following: Influence of implants on outcome Influence of surgical techniques on outcome Influence of bone grafting on outcome Identification of risk factors for failure Identification of postoperative rehabilitation programs and its possible influence on the outcome Influence of fracture type on outcome To serve as a comparative dataset for future studies with improved implants and techniques

Official Title
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Multicenter Prospective Registry for Periprosthetic Fractures After Hip or Knee Arthroplasty

Conditions
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Periprosthetic Fractures, Periprosthetic Fracture Around Prosthetic Joint Implant

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age ≥18 years Post-operative PPFx after total or hemi hip or total or unicondylar knee arthroplasty (including the acetabulum, femur, patella and proximal tibia) requiring osteosynthesis alone or component revision plus plate/nail osteosynthesis Informed consent obtained, i.e.: Ability of the patient or assigned representative to understand the content of the patient information / Informed Consent Form Signed and dated EC / IRB approved written informed consent Ability to attend post-operative follow up visits Exclusion Criteria: Pregnancy or women planning to conceive within the study period Prisoner

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Classification of the fracture | Classification of the fracture using the UCS and some parts of the AO/OTA fracture classification system. | Pre-operatively (Day -1) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Fracture mechanism | High / low energy trauma, pathological fracture, stem stability | Pre-operatively (Day -1) | 
| Rehabilitation program | weight bearing, bedrest, splint | Up to 12 months | 
| Function of hip or knee | Harris Hip Score or Knee Society score | Up to 12 months | 
| Health related quality of life | PROMIS pain interference and physical activity | Up to 12 months | 
| Fracture healing | by RUSH or RUST score | Up to 12 months | 
| pain visual analog scale (VAS) and pain medication | Using the pain visual analog scale (VAS) and pain medication | Up to 12 months |