Hormonal Effect of Different Menstrual Phases on Dynamic Balance in Postpubertal Females

Study Overview
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Brief Summary
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High rate of injuries detected during certain periods of menstrual cycle, raised the suggestion of the effecacy of the female sex hormones on soft tissue and neuromuscular control with subsequent deterioration of postural stability and high injury prevalence in post pubertal females so the aim of the present study is to investigate the effect of female sex hormones on postural stability in post pubertal females.

Detailed Description
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Thirty-six post pubertal females will participate in this study. They will be selected from students and graduates of Faculty of Physical Therapy, Deraya University and they will be assigned into one group. Postural stability assessment will be carried out throughout three menstrual cycle phases, early follicular, ovulation and mid luteal phases by Biodex balance system. The timing of menstrual cycle phases will be determined by measuring serum estradiol and progesterone level. The exact time of ovulation will be determined by urine lutenizing hormone ovulatory strip test.

Official Title
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Hormonal Effect Of Different Phases Of Menstrual Cycle On Postural Stability In Postpubertal Females: A Cross Sectional Repeated Measure Design

Conditions
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Menstrual Cycle

Intervention / Treatment
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* Other: no intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All females will be virginal. Their ages will range from 15-25 years. Their body mass index (BMI) will range from 18-27 kg/m2. All females will have regular menstrual cycle within average of 28 days. Exclusion Criteria: Females having menstrual irregularity. Use of oral contraceptives or any hormonal treatment in the previous six months before participate in this study. History of lower extremity injury, surgery or pain during ADL. Females having any vestibular problems , otitis media, labyrinthitis or any inner ear problems that affect balance.

Ages Eligible for Study
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Minimum Age: 16 Years
Maximum Age: 25 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| one group<br> | Other: no intervention<br>* no intervention, not applicable<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| serum estradiol level | used for accurate timing of menstrual cycle phases, follicular and midluteal. | two months | 
| Anetro-posterior stability index | Indicator for dynamic postural stability | two months | 
| Medio-lateral stability index | Indicator for dynamic postural stability | two months | 
| Overall stability index | Indicator for dynamic postural stability | two months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Sex hormones, Postural stability, Menstrual cycle.