Study of Lipid Profile of Patients With Chronic Coronary Syndromes at Sohag University Hospital

Study Overview
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Brief Summary
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Chronic coronary syndrome (CCS) is a newly described classification devised by the European Society of Cardiology (ESC) 2019 to replace the term Stable Coronary Artery Disease (CAD). The main reason for effecting the change is the term is thought to better describe the disease process and encompass a wider spectrum of clinical, pharmacological, and pathophysiological entities. Using this new term, the disease atherosclerosis manifests as CAD is categorized into Acute Coronary Syndrome (ACS) and CCS. The main focus of introducing the concept of CCS is on the fact that CAD is a continuous phenomenon involving intravascular plaque aggregation and progression which has different evolutionary phases. Dyslipidemia is recognized as a prominent risk factor for cardiovascular (CV) disease. It is characterized by an elevation of serum total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), or triglycerides (TG) and reduced serum high-density lipoprotein cholesterol (HDL-C) concentration . Genetically determined and metabolically induced disturbances in lipid metabolism, as manifested in several types of dyslipidemia, have been shown to be causally related to the development of coronary artery disease (CAD). A diversity of clinical and angiographic studies has been made to evaluate the linkage between plasma lipid-control therapy in the development of recurrent cardiovascular events. Independent predictors of recurrent CVD events or death include age, smoking, hypertension (HTN), dyslipidemia, diabetes mellitus, chronic kidney disease, and the underutilization of medications recommended by current treatment guidelines.

Official Title
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Study of Lipid Profile of Patients With Chronic Coronary Syndromes at Sohag University Hospital

Conditions
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Ischemic Heart Disease, Dyslipidemias

Intervention / Treatment
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* Diagnostic Test: lipid profile test .


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All patients have chronic coronary disease at Sohag University hospital who recieve drugs of anti hyperlipidemia . Exclusion Criteria: Patients with first attack of acute coronary syndrome . Young patients <18 years . Old patients >65 years.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Ischemic heart disease patients .<br>Study of lipid profile of patients with chronic coronary syndromes who recieve drugs of anti hyperlipidemia at the cardiology clinic of sohag university hospital. | Diagnostic Test: lipid profile test .<br>* Assesment of lipid profile of patients (cholesterol level ,TG ,VLDL )<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Dyslipidemia in chronic coronary syndrome | Pattern of dyslipidemia among patients with chronic coronary syndromes at sohag university hospital. | one year |