Hemodynamic Effects During Land vs Water Exercise for Older Adults With Orthostatic Hypotension

Study Overview
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Brief Summary
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The purpose of the study is to understand how blood pressure, heart rate, and symptoms of low blood pressure (such as dizziness or nausea) are affected by positional changes and exercise when on land or in the water for people who tend to experience orthostatic hypotension.

Official Title
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Hemodynamic Effects During Land vs Water Exercise for Older Adults With Orthostatic Hypotension

Conditions
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Orthostatic Hypotension

Intervention / Treatment
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* Behavioral: Water exercise
* Behavioral: Land exercise


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Self-report of dizziness upon standing (from sit or supine position) or known diagnosis of orthostatic hypotension Able to stand independently for 3-5 consecutive minutes Able to walk independently (with or without an assistive devise) Medically stable for last month Score of 3 or greater on Mini-Cog (standardized outcome measure to detect dementia) Full coronavirus vaccination Exclusion Criteria: Diagnosis of dementia Contraindication for pool exercise (such as infected open wounds, fecal incontinence, diarrhea.)

Ages Eligible for Study
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Minimum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Water condition<br>Participants blood pressure, heart rate and self-reported symptoms (such as dizziness) will be collected multiple times during sitting, standing and walking conditions when in a pool. | Behavioral: Water exercise<br>* Participants will be asked to sit and stand multiple times (before, immediately after, and 2 hours after a 15-minute walking session). The walking session will consist of 3 minutes of walking at a light intensity followed by 9 min of walking at a moderate intensity and a 3-minute cool down walking at a light intensity. This walking session will occur in a pool.<br>|
| Active Comparator: Land condition<br>Participants blood pressure, heart rate and self-reported symptoms (such as dizziness) will be collected multiple times during sitting, standing, and walking conditions when on land. | Behavioral: Land exercise<br>* Participants will be asked to sit and stand multiple times (before, immediately after, and 2 hours after a 15-minute walking session). The walking session will consist of 3 minutes of walking at a light intensity followed by 9 min of walking at a moderate intensity and a 3-minute cool down walking at a light intensity. This walking session will occur on land.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Systolic blood pressure (mmHg) | Blood pressure will be taken with an automated blood pressure device | <1 minute upon standing | 
| Diastolic blood pressure (mmHg) | Blood pressure will be taken with an automated blood pressure device | <1 minute upon standing | 
| Self-reported orthostatic hypotension symptoms | A self-reported instrument assessing symptoms from low blood pressure experienced upon standing or after prolonged upright activities. Possible scores range from 0 (no symptoms) to 10 (worse possible symptoms) | 2 minutes |