linjc16/ctgov huggingface dataset:
Adapting Web-based Instruction to Baseline Knowledge of Physicians-in-training

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to compare an adaptive Web-based learning system to a non-adaptive system for teaching physicians-in-training about ambulatory medicine.

Detailed Description
-----------------
Not all Web-based instruction is equally effective at facilitating learning. Adaptation to characteristics of individual learners may enhance Web-based learning by emulating a face-to-face teacher's response to a learner's needs. Learner baseline knowledge level is one variable to which Web-based instruction may adapt. We will enhance Web-based instructional modules used in the Internal Medicine resident continuity clinics so that they adapt to learner baseline knowledge. We will then compare the adaptive Web-based format to the standard format. We hypothesize that the adaptive format will have higher learning efficiency, and that achievement will be similar for the two groups. We also hypothesize that residents will prefer the adaptive format and find it to be more motivating than the standard format.

Official Title
-----------------
Adapting Web-based Instruction to Learner Baseline Knowledge: A Randomized Controlled Trial

Conditions
-----------------
Medical Training, Medical Education, Internship and Residency

Intervention / Treatment
-----------------
* Behavioral: knowledge-adaptive Web-based instruction


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Internal medicine residents (Mayo-Rochester campus)

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: knowledge-adaptive Web-based instruction|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Knowledge |  |  | 
| Learning efficiency |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Format preference |  |  | 
| Time to complete module |  |  | 
| Motivation |  |  |
Transoral Versus Transbuccal Placement of Bicortical Screws During Orthognathic Surgery

Study Overview
=================
Brief Summary
-----------------
Bicortical screws have been widely used for mandibular osteosynthesis during orthognathic surgery.Transoral placement of bicortical screws is a rigid fixation method in orthognathic surgery, which is less often used. The aim of this study was to compare postoperative outcome of transoral versus transbuccal bicortical screw placement during orthognathic surgery. This study comprises an academic, retrospective, monocentric study in which the charts of orthognathic patients operated between January 2010 and December 2012 were retrospectively reviewed. Postoperative complications were registered. Demographic, dental and surgical parameters are examined as potential risk factors for the occurence of postoperative complications.

Conditions
-----------------
Prognathism, Retrognathia, Jaw Abnormalities

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients of all ages patients of all genders patients who had undergone a bimaxillary osteotomy, a bilateral sagittal split ramus osteotomy (BSSO), a BSSO with a chin osteotomy or a trimaxillary osteotomy Exclusion Criteria: patients where cement had been used at the osteotomy sites patients who had undergone a multisegmented mandibular osteotomy patients who had undergone an osteosynthesis with plates patients where the postoperative orthopantomogram was unavailable patients where data regarding the type of screw placement was unavailable
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| transoral group<br>orthognathic patients that were treated with a transoral surgical approach | |
| transbuccal group<br>orthognathic patients that were treated with a transbuccal surgical approach | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative complications (rate of screw removal and/or infection) |  | within 4 weeks postoperative | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The value of demographic, dental and surgical parameters as potential risk factors for the occurence of postoperative complications |  | within 4 weeks postoperative | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
transoral approach, transbuccal approach, postoperative complications
Ultrasound Guidance for Intravenous Cannulation in Emergency Department Patients.

Study Overview
=================
Brief Summary
-----------------
A randomized trial of the use of ultrasound by emergency physicians in the placement of intravenous catheters in emergency patients who are found to have difficult intravenous access (defined as two failed attempts by nursing staff).

Official Title
-----------------
Ultrasound-Guided Peripheral Intravenous Cannulation in Emergency Department Patients With Difficult IV Access: a Randomized Trial.

Conditions
-----------------
Difficult IV Access

Intervention / Treatment
-----------------
* Device: ultrasound


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients requiring an IV in the emergency department and who have two failed attempts by nursing staff Exclusion Criteria: emergent need for IV access

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Ultrasound<br>use of ultrasound | Device: ultrasound<br> <br> |
| No Intervention: no ultrasound<br>no ultrasound | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of IV Attempts |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Time to placement of IV catheter |  |  | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
ultrasound, iv access, Patients with difficult iv access in emergency departments.
Investigation of the Duration of Low-intensity Focused Ultrasound

Study Overview
=================
Brief Summary
-----------------
This project examines the effects of various durations of noninvasive neuromodulation on muscle contractions. The investigators believe this study will help to better understand noninvasive brain stimulation techniques that may have the potential to aid in addiction, pain, and mental health issues. Participants undergo structural imaging, a functional Magnetic Resonance Image (fMRI) and computed tomography (CT). These images are used to align the low-intensity focused ultrasound (LIFU) and transcranial magnetic stimulation (TMS) devices to temporarily change brain activity. Electromyography (EMG) will be used to record muscle contractions of the hand.

Official Title
-----------------
Investigation of the Duration of Low-intensity Focused Ultrasound

Conditions
-----------------
Development of LIFU for Clinical Purposes

Intervention / Treatment
-----------------
* Device: Low-Intensity Focused Ultrasound


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Above criteria and must understand and speak English. Exclusion Criteria: Contraindications to MRI, CT, or TMS Claustrophobia Pacemaker, aneurysm clips, neurostimulators, cochlear implants, metal in eyes, steel worker, or other implants. Pregnancy Active medical disorder or treatment with potential CNS effects History of neurologic disorder History of head injury resulting in loss of consciousness for >10 minutes History of alcohol or drug dependence

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Basic Science
Intervention Model: Single Group Assignment
Interventional Model Description: Multi-visit study, testing various LIFU durations
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Duration Trials<br>Six different durations (three intermittent and three continuous) of LIFU application will be tested across six study sessions. Response recorded using TMS and EMG. | Device: Low-Intensity Focused Ultrasound<br>* LIFU application using various durations, responses of neuromodulation recorded using TMS and EMG.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Waveforms | Changes in waveform peak will be observed per each variable application of LIFU | Outcomes assessed throughout participation - an average of 3 weeks. | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
low-intensity focused ultrasound, transcranial magnetic stimulation
Use of Otoscope as a Non-Invasive Tool for Diagnosis of Pilomatricoma

Study Overview
=================
Brief Summary
-----------------
Stanford University Dermatology Clinics and Lucile Packard Children's Hospital are evaluating the use of the otoscope for the diagnosis of skin lesions. We are particularly looking for children and/or adults with nodules, cysts, tumors, or pilomatricomas. The study will take 15-30 minutes and we will use light to examine and take a picture of your skin lesion. There is no monetary compensation for participating in the study.

Detailed Description
-----------------
Pilomatricoma is a benign tumor that presents as a 3-30mm firm, solitary, deep dermal or subcutaneous tumor on the head, neck, or upper extremities. The clinical diagnosis is often made by the firm, sometimes rock hard texture of the skin. The diagnosis can be confirmed by a skin biopsy and/or excision of the lesion. We have recently noted that pilomatricomas appear as a black mass in the skin when the lesion is transilluminated by placing the light of a fiberoptic otoscope adjacent to the skin lesion. We would like to confirm our impression by a prospective study using transillumination to examine subcutaneous tumors in the skin. Pilomatricoma is also known as a benign calcifying or calcified epithelioma, pilomatrixoma, or a calcifying epithelioma of Malherbe.

Official Title
-----------------
Use of Otoscope as a Non-Invasive Tool for Diagnosis of Pilomatricoma

Conditions
-----------------
Pilomatrixoma

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria:- Potential participants will be any patient that is seen at Stanford Dermatology or LPCH that has a cyst, nodule, vesicle, tumor, or possible pilomatricoma Exclusion Criteria:- Inability of subject or subject's guardian to understand informed consent form.
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
Effect of Community Social Mobilization for the Prevention of HIV in Young South African Women

Study Overview
=================
Brief Summary
-----------------
The overall purpose is to assess whether a community social mobilization (CSM) program focused on young men ages 18-35 years of age changes gender norms in the community. The secondary purpose is to determine if there is a combined effect of CSM and HPTN 068 (Conditional Cash Transfers) on HIV and HSV-2 incidence. The goal of the mobilization activities is to engage young men around the issues of gender norms, intimate partner violence and HIV risk and to encourage them to take action to protect young women and reduce HIV risk in their communities.

Official Title
-----------------
Effect of Community Social Mobilization for the Prevention of HIV in Young South African Women

Conditions
-----------------
Gender Relations

Intervention / Treatment
-----------------
* Behavioral: Community Social Mobilization program


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Quantitative Work Men and women ages 18-35 years Have lived in study area continuously for the past 12 months Able and willing to provide informed consent Qualitative Work Men and women ages 18-99 years A community member, CAT member or community mobilizer Able and willing to provide informed consent

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 99 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Community Social Mobilization Program<br>A manualized intervention developed with Sonke Gender Justice Network using a workshop intervention manual and a community mobilization toolkit will be used. | Behavioral: Community Social Mobilization program<br> <br> |
| No Intervention: Control Arm<br>The Control Arm does not receive the Community Mobilization Intervention | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes in Gender Equitable Mens Scale (GEMS) |  | Baseline and 24 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The number of unprotected sex acts |  | Baseline and 24 months | 
| Concurrency | The investigators will measure concurrency by assessing the date of first and last sex and whether a relationship is ongoing among the last 3 partners in the last 12 months. | Baseline and 24 months | 
| Experience of perpetration of Intimate partner violence (IPV) |  | Baseline and 24 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Community Mobilization, HIV, Intimate Partner Violence, Gender Norms
International Registry of Thrombotic APS Patients Treated With Direct Oral Anticoagulants

Study Overview
=================
Brief Summary
-----------------
This registry, currently being established will ensure consistency of data collection and provide safety information in non high-risk APS patients currently on DOACs.

Official Title
-----------------
OBServaToire INternational Des Patients AnTiphospholipidEs traités Par Anticoagulants Oraux Directs

Conditions
-----------------
Antiphospholipid Syndrome, Thrombosis, Anticoagulants Causing Adverse Effects in Therapeutic Use

Intervention / Treatment
-----------------
* Drug: Rivaroxaban


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patient receiving a comprehensive information about the study, and not opposed to participate Age ≥ 18 yo Classification of definite APS according to revised Sapporo-Sydney criteria Direct oral anticoagulant treatment prescribed during at least 6 months or with the possibility of follow-up of at least 6 months Exclusion Criteria: Incomplete revised Sapporo-Sydney criteria No data regarding the recurrent thrombosis Pregnant woman Age < 18 yo
Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: Rivaroxaban|Rivaroxaban 10 mg or 15 mg or 20 mg OD Dabigatran 110 mg or 150 mg BID Apixaban 2.5 mg or 5 mg or 10 mg BID|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rate of Recurrent Thrombosis | Rate of Recurrent Thrombosis either arterial, venous or microvascular confirmed by a relevant exam | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rate of Bleeding | Rate of Bleeding either severe or major or clinically relevant non-major bleeding according to ISTH classification | 6 months | 
| Rate of Non-Criteria Manifestations | Rate of Non-Criteria Manifestations according to Sydney criteria | 6 months | 
| Adherence to treatment | Rate of patients who have a good adherence to oral anticoagulants assessed by the Girerd questionnaire | 6 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
antiphospholipid syndrome, direct oral anticoagulants
Glomerular Filtration Rate (GFR) Reporting on Nephrology Referral Patterns by Internists

Study Overview
=================
Brief Summary
-----------------
The addition of an estimate value of glomerular filtration rate (GFR) per Modification of Diet in Renal Disease [MDRD] (LEVEY) equation is being included and reported on all routine chemistry panels in the experimental group. The control group is only having serum creatinine, the current standard of care, reported on routine chemistry panels.

Detailed Description
-----------------
All patients already referred to or being followed by nephrologists were excluded. Inclusion criteria were all patients in the Internal Medicine clinic at NMCSD who were sent to the lab to obtain routine chemistry panels for follow up by their primary care providers. The primary outcome is increased referral to nephrology in accordance with NKF K/DOQI guidelines if GFR values are reported on routine chemistry panels. Key secondary outcomes are Primary Care Provider knowledge of NKF K/DOQI guidelines, specifically when patients with chronic kidney disease need to be referred to a nephrologist for further evaluation.

Official Title
-----------------
The Effect of MDRD GFR Reporting on Nephrology Referral Patterns by Internists

Conditions
-----------------
Chronic Kidney Disease

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: All patients in the Internal Medicine Clinic at Naval Medical Center, San Diego (NMCSD) who were sent to the lab to obtain follow up by their primary care providers. Exclusion Criteria: All patients referred to or being followed by nephrologists.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
GFR, serum creatinine
Comparison of Combination Antibiotics Eyedrop to Artificial Tear in Hordeolum After Incision and Curettage

Study Overview
=================
Brief Summary
-----------------
To compare the effectiveness of combined antibiotic ophthalmic solution (neomycin sulfate, polymyxin B sulfate and gramicidin) with placebo (artificial tear) in the treatment of hordeolum after incision and curettage

Detailed Description
-----------------
Hordeolum is a common eyelid disease. In case of mass, I&C is required but role of antibiotic after I&C is not clear. It may not need in post drainage period.

Official Title
-----------------
Dose Antibiotic Need in Hordeolum After Incision and Curettage? : A Randomized, Placebo-controlled Trial

Conditions
-----------------
Hordeolum

Intervention / Treatment
-----------------
* Drug: neomycin sulfate, polymyxin B sulfate and gramicidin
* Drug: Artificial tear


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: at least 5-millimeters hordeolum the onset within 7 days Exclusion Criteria: previous incision and curettage of the same site within 1 month or more than 3 times lesions in the adjacent areas suggesting of complications associated with hordeolum such as preseptal cellulitis or blepharitis The patients with immunodeficiency, history of bleeding tendency allergy to aminoglycoside, polymyxin B, gramicidin, xylocaine and povidone iodine

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Placebo Comparator: B<br>Artificial tear containing antibiotic solution base | Drug: Artificial tear<br>* 4 times daily<br>* Other names: Lacoph;|
| Experimental: A<br>combined antibiotic ophthalmic solution (neomycin sulfate, polymyxin B sulfate and gramicidin) | Drug: neomycin sulfate, polymyxin B sulfate and gramicidin<br>* to the effected eye 4 times a day<br>* Other names: Polyoph;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain scale |  | 1,3,7 days after treatment | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mass size and duration of cure |  | 1, 3, 7, 30 days after treatment | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Antibiotics, hordeolum