Incidence of Poorly Controlled Diabetes in Surgical Population

Study Overview
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Brief Summary
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Our study aims to determine the incidence of undiagnosed and poorly controlled diabetes among surgical patients in Singapore using preoperative HbA1c as a screening tool.

Detailed Description
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The study aims to determine the incidence of undiagnosed and poorly controlled diabetes among surgical patients in Singapore using preoperative HbA1c as a screening tool. The investigators aim to follow up on the incidence of perioperative complications in this cohort. In the longer term, the investigators hope to evaluate the role of a preoperative diabetic screening and intervention program as an opportunistic teachable moment for surgical patients. This may help to achieve greater control of the disease burden in Singapore. Specific aims: Specific Aim 1: To establish the incidence of undiagnosed diabetes/prediabetes among surgical patients in Singapore, based on HbA1c level ≥ 6.1% prior to surgery Specific Aim 2: To establish the incidence of poorly-controlled diabetes among surgical patients in Singapore, based on HbA1c level ≥ 8% prior to surgery Specific Aim 3: To identify and characterize any association between preoperative HbA1c level and postoperative outcomes

Official Title
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Incidence of Undiagnosed and Poorly Controlled Diabetes Mellitus Among Surgical Patients and Its Association With Perioperative Outcomes: a Single-centre Prospective Cohort Study

Conditions
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Diabetes Mellitus

Intervention / Treatment
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* Other: HbA1C


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age >21 years old able to give informed consent Scheduled to have preoperative blood taken during clinic visit Exclusion Criteria: Age < 21 years old unable to given informed consent Not required to have routine preoperative blood tests taken

Ages Eligible for Study
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Minimum Age: 21 Years
Maximum Age: 99 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Cohort<br>We propose a prospective, observational single-centre pilot study in the PAC (SGH), on participants aged 21 years and above. A HbA1c test will be added to their routine preoperative blood tests. The incidence of newly-diagnosed DM/pre-diabetes (HbA1c ≥6.1%) and poorly controlled DM (HbA1c ≥ 8%), demographic details and presence of significant comorbidities will be analysed. | Other: HbA1C<br>* To take additional blood test of HbA1C once patient consented to the study<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Diabetes incidence | To determine the incidence of undiagnosed and poorly controlled diabetes among surgical patients in Singapore | 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Association of HbA1C levels with post operative complications | To identify and characterize any association between preoperative HbA1c level and postoperative complications, including morbidity and mortality. | 12 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Incidence of Diabetes Mellitus, HbA1C