Validation of Kaihani Score for Gambling Addiction

Study Overview
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Brief Summary
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The Kaihani Score is a blood based means of assessing molecules believed to be associated with gambling addiction. The current clinical trial will assess the Kaihani Score in 3 groups: Group 1: 10 patients with no personal or family problems with gambling as assessed by the PG-YBOCS (obsessions-compulsions scale Yale-Brown (Y-BOCS), adapted for pathological gambling) (PG-YBOCS). Group 2: 10 patients with moderate gambling addiction as assessed by the PG-YBOCS (obsessions-compulsions scale Yale-Brown (Y-BOCS), adapted for pathological gambling) (PG-YBOCS). Group 3: 10 patients with severe gambling addiction as assessed by the PG-YBOCS (obsessions-compulsions scale Yale-Brown (Y-BOCS), adapted for pathological gambling) (PG-YBOCS). The goal of the study is to confirm preliminary efficacy of the Kaihani Score as a blood based means of assessing gambling propensity.

Official Title
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Diagnostic Ability of Plasma Based Neuromodulatory Cytokine Production (Kaihani Score) in Gambling Addiction

Conditions
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Gambling Addiction

Intervention / Treatment
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* Diagnostic Test: Kaihani Score


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients with a diagnosis of pathological gambling (DSM IV criteria) First-time consultants. Without psychotropic treatment or treatment with a stable and unchanged for over a month. Exclusion Criteria: Pregnant women and patients with hearing disorders Epilepsy (untreated or poorly balanced) Focal brain injury, whatever its origin (vascular, traumatic, tumor or infectious) History of head trauma with loss of consciousness, Administration of drugs or substances lowering the seizure threshold Sleep deprivation, jet lag, or drug withdrawal. Participants with a problem of uncorrected visual acuity. Other current addiction.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Control<br>10 patients with no personal or family problems with gambling as assessed by the PG-YBOCS (obsessions-compulsions scale Yale-Brown (Y-BOCS), adapted for pathological gambling) (PG-YBOCS). | Diagnostic Test: Kaihani Score<br>* Assessment of neuromodulatory chemicals in peripheral blood plasma samples.<br>|
| Moderate Gamblers<br>10 patients with moderate gambling addiction as assessed by the PG-YBOCS (obsessions-compulsions scale Yale-Brown (Y-BOCS), adapted for pathological gambling) (PG-YBOCS). | Diagnostic Test: Kaihani Score<br>* Assessment of neuromodulatory chemicals in peripheral blood plasma samples.<br>|
| Severe Gamblers<br>10 patients with severe gambling addiction as assessed by the PG-YBOCS (obsessions-compulsions scale Yale-Brown (Y-BOCS), adapted for pathological gambling) (PG-YBOCS). | Diagnostic Test: Kaihani Score<br>* Assessment of neuromodulatory chemicals in peripheral blood plasma samples.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Assessment of Kaihani Score | Kaihani Score will be compared between non-gamblers, moderate gamblers, and severe gamblers. | 1 Week | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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addiction, BDNF