Vaso-inotropic Score and ECMO-VA Support in Post-cardiotomy Cardiogenic Shock.

Study Overview
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Brief Summary
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Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a well-established lifesaving treatment for refractory cardiogenic shock, with or without concomitant respiratory failure. VA-ECMO is usually started in presence of refractory low cardiac output syndrome following CPB weaning. Currently, there is no consensus about the best timing for implantation and initiation of VA-ECMO in this setting. Some publications have suggested that VIS score could be used to determine the necessity of VA-ECMO in cardiologic area. It was demonstrated that a VIS score between 20 and 40 may be a cut-off value to discuss the implantation of VA-ECMO. Post cardiotomy shock is a very interesting setting because the timing of cardiogenic shock is known and several bias are more controlled than in medical area. Based on the well-established ability of VIS Score in predicting mortality, we will investigate the role of the VIS Score as a determinant for early VA-ECMO implantation in patients suffering of post-cardiotomy cardiogenic shock.

Official Title
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Vaso-inotropic Score and ECMO-VA Support in Post-cardiotomy Cardiogenic Shock.

Conditions
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EMCO-VA

Intervention / Treatment
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* Other: data collection


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: age over 18 years Cardiac surgery with cardiopulmonary bypass Post cardiotomy cardiogenic shock ECMO-VA implanted in OR Exclusion Criteria: LVAD Heart transplantation Incomplete data in relation to outcomes Cardiac arrest

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| With ECMO-VA<br>postcardiotomy cardiogenic shosck supported by ECMO-VA | Other: data collection<br>* age, gender, body weight, height, personal medical history, ASA score, EuroSCORE2, type of cardiac surgery, the preoperative left ventricular ejection fraction, the duration of CPB, the duration of aortic clamping, the need for intraoperative blood transfusion, norepinephrine, dobutamine, creatinine value, time to extubation (hours), any occurrence of complications during the stay in the ICU or in the hospital, and the LOS in the ICU and hospital<br>|
| Without ECMO-VA<br>Post cardiotomy cardiogenic shock medically treated (inotrope and vasopressor) | Other: data collection<br>* age, gender, body weight, height, personal medical history, ASA score, EuroSCORE2, type of cardiac surgery, the preoperative left ventricular ejection fraction, the duration of CPB, the duration of aortic clamping, the need for intraoperative blood transfusion, norepinephrine, dobutamine, creatinine value, time to extubation (hours), any occurrence of complications during the stay in the ICU or in the hospital, and the LOS in the ICU and hospital<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pourcentage of death |  | Day 30 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 1 - Number of complications | 1- cardiac, neurological, renal, respiratory, red blood transfusion complication | Day 30 | 
| 2 - number of days in intensive care |  | through study completion, up to 15 days | 
| 3 - number of days in hospital |  | through study completion, up to 3 months |