Safety Study of Subclavian and Internal Jugular Venous Catheterization

Study Overview
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Brief Summary
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There is no randomized controlled trial to compare the rates of complications associated with internal jugular and subclavian venous catheterization. The aim of this study is to compare mechanical, infectious, and thrombotic complications of internal jugular and subclavian venous catheterization. An improved understanding of CVC-related risks might help clinicians to choose one approach over the other in specific clinical settings.

Detailed Description
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Central venous catheterization is often necessary to treat critically ill patients hospitalized in intensive care units (ICUs). However, this procedure may lead to serious and sometimes life-threatening complications, including mechanical, infectious, or thrombotic complications. The choice of insertion site can influence the incidence and type of such complications. The most frequently used sites for CVC insertion are the internal jugular and the subclavian vein. However, in an individual patient, criteria for choosing one approach over the other remain unclear.

Official Title
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A Randomize Controlled Trial to Compare the Complications of Subclavian and Internal Jugular Venous Catheterization in Critically Ill Patients

Conditions
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Time to Insertion, Rates of Complications

Intervention / Treatment
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* Device: Central venous catheter


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: admission to ICU requiring central venous catheterization without contraindications to attempt both jugular and internal jugular access Exclusion Criteria: the presence of a central venous catheter at admission central venous catheterization within 2 weeks prior to admission emergency catheterization for a life-threatening situation major blood coagulation disorders anatomic defect precluding catheterization at either site skin lesions or recent surgery at either site

Ages Eligible for Study
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Minimum Age: 20 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Internal jugular vein<br> | Device: Central venous catheter<br>* Central venous catheter insertion to subclavian vein<br>* Other names: venous access;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Time to completely insertion |  | 1 hour | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| rates of mechanical, infectious, and thrombotic complications |  | 14 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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central venous catheter, complications, internal jugular vein, randomized trial, subclavian vein