Efficacy Study of Acupuncture to Relieve Symptoms of Chronic Prostatitis

Study Overview
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Brief Summary
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Limited evidence suggests that acupuncture may help relieve symptoms of chronic prostatitis/chronic pelvic pain syndrome. This study evaluated if acupuncture twice weekly for 10 weeks would help ameliorate symptoms of CP/CPPS.

Detailed Description
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Various studies have reported that this acupuncture able to relieve symptoms of chronic prostatitis (CP)/ chronic pelvic pain syndrome (CPPS). However, controversy exists on the efficacy of this technique due to poor experimental designs and lack of placebo controls in these experiment. This study is the first randomised controlled study which will evaluate if acupuncture for 10 weeks will help improve symptoms of CP/CPPS

Official Title
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A Double Blind, Sham Controlled Trial Evaluating the Efficacy of Acupuncture in Relieving Symptoms of Chronic Prostatitis/ Chronic Pelvic Pain Syndrome

Conditions
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Prostatitis

Intervention / Treatment
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* Procedure: Acupuncture


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Symptoms of discomfort or pain in the pelvic region for at least a three (3) months period within the last six (6) months. Moderate overall score on the NIH-CPSI (overall score more than 15 out of a potential of 0-43 points) Diagnosed as having CPPS Category III Participant is willing to undergo 10 weeks of acupuncture treatment Exclusion Criteria: History of prostate, bladder or urethral cancer. Inflammatory bowel disease (such as Crohn's disease or ulcerative colitis, but not irritable bowel syndrome). Undergone pelvic radiation or systemic chemotherapy, intravesical chemotherapy or intravesical BCG. Treated for unilateral orchialgia without pelvic symptoms. Active urethral stricture. Undergone TURP, TUIP, TUIBN, TUMT, TUNA, balloon dilation of the prostate, open prostatectomy or any other prostate surgery or treatment such as cryotherapy or thermal therapy. Neurological impairment or psychiatric disorder preventing his understanding of consent and his ability to comply with the protocol. Liver disease. Diagnosed as acute or chronic bacterial prostatitis. History of urinary tract infection positive uropathogen for the past year. Taking medications which could affect the lower urinary tract function History of type 1 or 2 diabetes. Treated/currently undergoing treatment with acupuncture for any other illness including prostatitis for the past 6 months. Refusal to be needled or any form of bleeding disorder.

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: Acupuncture|nan|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Six point drop in NIH-CPSI total Score |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Individual domains of the NIH-CPSI |  |  | 
| Patient reported Global Response Assessment |  |  | 
| International Prostate Symptom Score |  |  | 
| International Index of Erectile Function |  |  | 
| Brief Pain Inventory- Short Form |  |  | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Prostatitis