Study of the Effect of General Anesthesia on Children's Behavior

Study Overview
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Brief Summary
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This topic speculates that there is an interaction between family environment and anesthetic drug exposure on children's behavior. Different family environments have different response to anesthetic drug exposure. Children living in a specific family environment may be more susceptible to the effects of anesthetic drugs. People who are susceptible to exposure to narcotic drugs. In order to clarify this hypothesis and discover specific family environment factors that interact with anesthetic drug exposure, this project intends to establish a retrospective cohort study, through hierarchical analysis and other means, to clarify the behavioral changes of children in different family environments after exposure to anesthetic drugs. Provide theoretical support for the safe application of clinical children's anesthetics.

Official Title
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A Retrospective Study of the Effect of General Anesthesia on Children's Behavior

Conditions
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Behavior

Intervention / Treatment
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* Other: Achenbach Child Behavior Checklist （CBCL）scale


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Children aged 0-5 who underwent surgery at Shanghai Ninth People's Hospital Current age is less than 18 years old No surgical complications such as acute infectious diseases, systemic diseases Exclusion Criteria: History of neonatal hypoxic ischemic encephalopathy and bilirubin encephalopathy There are genetic diseases or chromosomal diseases, neurological diseases (including epilepsy, congenital diseases), or a history of head trauma, a history of central nervous system infectious diseases, high fever convulsions, congenital heart disease, tumor diseases, and Patients with blood diseases People who have autism, attention deficit hyperactivity disorder, or have received behavioral related treatments and interventions Those who have undergone cardiovascular surgery, neurosurgery, or those with unstable hemodynamics during surgery Those who cannot be contacted, refused to join the group, the questionnaire information does not match the medical records, or the complete medical records cannot be obtained

Ages Eligible for Study
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Minimum Age: 5 Years
Maximum Age: 18 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Control group<br>No general anesthesia between 0-3 years old or 0-5 years old | Other: Achenbach Child Behavior Checklist （CBCL）scale<br>* Use the Achenbach Child Behavior Checklist （CBCL）scale to assess children's behavior<br>|
| Single anesthesia group<br>Only once general anesthesia between 0-3 years old or 0-5 years old | Other: Achenbach Child Behavior Checklist （CBCL）scale<br>* Use the Achenbach Child Behavior Checklist （CBCL）scale to assess children's behavior<br>|
| Multiple anesthesia group<br>More than once general anesthesia between 0-3 years old or 0-5 years old | Other: Achenbach Child Behavior Checklist （CBCL）scale<br>* Use the Achenbach Child Behavior Checklist （CBCL）scale to assess children's behavior<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Achenbach Child Behavior Checklist （CBCL）scale | sorce（0-100），higher scores mean a worse | immediately after the procedure |