Acceptance & Commitment Therapy for Psychotic Inpatients

Study Overview
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Brief Summary
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The overarching aim of the research project is to investigate whether Acceptance & Commitment Therapy (ACT) is an efficacious psychotherapeutic method of treatment for inpatients suffering from acute psychosis. The method will be applied in two ways. Firstly, as an individual treatment for patients. Secondly, as an integrated part of the daily work on an inpatient ward, administered by nurses and assistant nurses trained in the method.

Official Title
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Acceptance & Commitment Therapy for Psychotic Inpatients

Conditions
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Acute Psychosis

Intervention / Treatment
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* Behavioral: Acceptance & Commitment Therapy
* Behavioral: Attention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Admitted to a specified psychiatric inpatient ward during the time-period of the study; psychotic spectrum diagnosis as specified in patient charts; assessed by contact person on the ward as having delusions or hallucinations. Exclusion Criteria: Cognitive difficulties to an extent where informed consent cannot be given.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Acceptance & Commitment Therapy<br>A variant of cognitive behavior therapy focused on acceptance and valued living in the presence of distressing symptoms. | Behavioral: Acceptance & Commitment Therapy<br>* A variant of cognitive behavior therapy focused on acceptance and valued living in the presence of distressing symptoms.<br>|
| Active Comparator: Attention<br>Supportive conversation at a frequency and length corresponding to the experimental condition. | Behavioral: Attention<br>* Supportive conversation at a frequency and length corresponding to the experimental condition.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rehospitalization | Whether or not, and if so for how many days, a patient has ben readmitted to inpatient care during the follow-up period. | 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bull's Eye Values Inventory | Quality of life instrument to be administered before treatment, after treatment, and at 3, 6 and 12 month follow-up. | 12 months | 
| EQ-5D | Health related quality of life instrument to be administered before treatment, after treatment, and at 3, 6 and 12 month follow-up. | 12 months | 
| Clinical Global Impression Scale | Symptom severity instrument to be administered before treatment, after treatment, and at 3, 6 and 12 month follow-up. | 12 months | 
| Acceptance & Action Questionnaire | Psychological flexibility instrument to be administered before treatment, after treatment, and at 3, 6 and 12 month follow-up. | 12 months | 
| Psychotic Symptom Rating Scales | Symptom severity instrument to be administered before treatment, after treatment, and at 3, 6 and 12 month follow-up. | 12 months | 
| Checklist of Unit Behaviors | Measure for degree of activity on the ward. | During inpatient care. | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Acceptance and commitment therapy, Cognitive behavior therapy