Clinical Performance of Different Resin Cements

Study Overview
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Brief Summary
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The clinical performance of different resin cements in adhesion of hybrid ceramic inlay and onlay restorations produced with CAD/CAM will be evaluated and compared. After obtaining a signed informed consent form from all the patients, all restorations will be placed by a single clinician. All hyrid ceramic restorations (Cerasmart, GC, Tokyo, Japan) will be produced using the same CAD/CAM CEREC Omnicam (Sirona Dental, Bensheim, Germany) system. 70 restorations will be divided into 2 groups: a self adhesive resin cement (RelyX U200 Automix, 3M ESPE, Seefeld, Germany), and an adhesive cement (G-Cem LinkForce, GC, Tokyo, Japan) which is applied after surface treatment (etch&rinse). All restorative procedures will be conducted according to manufacturers' instructions. Restorations will be scored using modified United States Public Health Service (USPHS) criteria after baseline, 6,12, 18, 24, 36 and 48 months. Descriptive statistics will be performed using Friedman test and Chi-square test.

Official Title
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Clinical Performance of Resin Cements in the Adhesion of CAD/CAM Restorations

Conditions
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Restoration of Posterior Teeth

Intervention / Treatment
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* Other: Self adhesive resin cement
* Other: Resin cement


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Healthy individuals with or without systemic disease Patiens older than 18 years old Good oral health Patients who at least have1 large and deep carious lesion or broken restoration in a vital tooth Patients who agreed to participate in the study after being informed about this study Exclusion Criteria: Patient with periodontal disease Patients with partial dentures Patients with bruxism Patients with malooclusion Non vital or endodontically treated teeth Preparetions under the cemento-enamel junction

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: RelyX U200 Automix Self Adhesive Resin Cement<br>Self Adhesive Resin Cement | Other: Self adhesive resin cement<br>* Self adhesive resin cement<br>* Other names: RelyX U 200;|
| Active Comparator: G-Cem LinkForce Resin Cement<br>Resin Cement system used after surface treatment | Other: Resin cement<br>* Resin Cement system used after surface treatment<br>* Other names: G-Cem LinkForce;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Clinical performance | 18 months- Modified United States Public Health Service | 18 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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CAD/CAM, Inlay, Onlay, Hybrid ceramic, Adhesive resin cement