Early Intensive Physical Therapy in Subarachnoid Hemorrhage

Study Overview
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Brief Summary
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This study will investigate the safety and feasibility of early intensive physical therapy for patients diagnosed with subarachnoid hemorrhage. Intervention will begin in the neurological Intensive Care Unit (ICU) and continue for 30 days or hospital discharge.

Official Title
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Effects of Early Intensive Physical Therapy for Patients With Subarachnoid Hemorrhage in a Neurological ICU

Conditions
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Subarachnoid Hemorrhage

Intervention / Treatment
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* Other: Physical Therapy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients diagnosed by CT scan or MRI with subarachnoid hemorrhage and admitted to the neurological ICU >48 hours. Exclusion Criteria: Significant language barrier that would limit the ability to participate in the physical therapy program Severe baseline physical or cognitive impairment that would impair their ability to participate in the protocol Patients whose vital signs are outside the accepted starting and stopping criteria outlined below: intracranial pressure ≤ 15 mm Hg Cerebral perfusion pressure >50 or <70 mm Hg Mean arterial pressure ≥ 80 and ≤ 110 Heart rate ≥40 and <140 bpm Pulse oximetry >88%

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Intervention arm<br>Early intensive physical therapy will be the intervention arm. There is not a control group. | Other: Physical Therapy<br>* Early Intensive Physical therapy in the ICU<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Improvement in Physical function in the ICU test (PFit) |  | Every 7 days until hospital discharge or 28 days of study enrollment | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Improvement in Activity Measure for Post-Acute Care (AM-PAC) mobility |  | Every 7 days until hospital discharge or 28 days of study enrollment | 
| Improvement in Timed up and Go (TUG) |  | Every 7 days until hospital discharge or 28 days of study enrollment | 
| Improvement in Postural Assessment Scale for Stroke Patients |  | Every 7 days until hospital discharge or 28 days of study enrollment | 
| Improvement in Medical Research Council (MRC) Muscle Sum Score |  | Every 7 days until hospital discharge or 28 days of study enrollment | 
| Improvement in Hand grip strength |  | Every 7 days until hospital discharge or 28 days of study enrollment | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Physical Therapy, early intervention