Evaluation of the Attitude of Pre Menopausal Women With Breast Cancer Faced With the Risk of Fertility Loss Caused by Chemotherapy

Study Overview
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Brief Summary
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To evaluate the attitude of pre menopausal women with breast cancer faced with the risk of loss of fertility caused by chemotherapy using EORTC's Fertility Questionnaire.

Detailed Description
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To characterize the attitude of pre menopausal patients with breast cancer regarding the risks of infertility based on the following variables: Age at diagnosis Number of children Will of having children Marital status Scholarity Period of time from the diagnosis Time of the last menstruation period Chemotherapy administration Clinical staging at the diagnosis Pathological evaluation Documentation of the cancer therapy

Official Title
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Evaluation of the Attitude of Pre Menopausal Women With Breast Cancer Faced With the Risk

Conditions
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Breast Cancer, Fertility

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Women with age ≥ 18 and ≤ 40 Indication of (neo) adjuvant chemotherapy Prior chemotherapy treatment Patients with menstrual periods in the last 6 months In use of contraceptive methods Without breast cancer recurrence Capacity to read and understand the informed consent Exclusion Criteria: Patients which received or with indication of definitive ovarian suppression (surgery and/or radiotherapy), except temporary pharmacological ovarian suppression Patients whom initiated chemotherapy treatment before entering the study Altered state of mind, dementia, or any other psychiatry problem that can interfere in the comprehension or interpretation of the informed consent. Previous diagnosis of infertility

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 40 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Pre menopausal women with breast cancer<br>Pre menopausal women with breast cancer prior treatment in face of infertility evoked by chemotherapy | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To analyze the number of pre-menopausal patients diagnosed with breast cancer that did not agree in receiving chemotherapy due to the risk of infertility |  | Baseline and 1 year after after the first interview | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Infertility risk for breast cancer patients after accepting chemotherapy |  | Baseline and 1 year after the first interview | 
| Minimal percentage of cure necessary for patients accept the chemotherapy treatment |  | Baseline and 1 year after the first interview | 
| Age when diagnosed |  | Baseline and 1 year after the first interview | 
| Number of children |  | Baseline and 1 year after the first interview | 
| Desire to have kids |  | Baseline and 1 year after the first interview | 
| Marital status |  | Baseline | 
| Scholarity |  | Baseline | 
| Period of time since the diagnosis |  | Baseline | 
| Chemotherapy scheme administration |  | Baseline and 1 year after the first interview | 
| Period of time from the last menstruation period |  | Baseline and 1 year after the first interview | 
| Description of quality of life of patients with the EORTC QLQ-BR23 |  | Baseline and 1 year after the first interview | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Breast cancer, Fertility