Impact of Adolescent Vaccine Reminder Notices Sent Via Preferred Method of Communication on HPV Vaccination

Study Overview
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Brief Summary
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Vaccine uptake in the United States is lower in rural areas, especially for HPV vaccine. Reminder/recall has been identified as an effective strategy to increase vaccination rates. This study will assess the impact by rurality of vaccine reminder notices sent via the parent's preferred method of communication on HPV vaccination among 12 year-old patients in a regional healthcare system.

Official Title
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Understanding and Addressing the Disparity in Vaccination Coverage Among U.S. Adolescents Living in Rural Versus Urban Areas

Conditions
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Papillomavirus Vaccines

Intervention / Treatment
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* Behavioral: Reminder Sent Via Preferred Method of Communication
* Behavioral: Reminder Sent Via Mailed Letter


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Marshfield Clinic Health System patient aged 12 years with at least one preventive visit or two evaluation & management visits with a Marshfield Clinic Health System provider in the last 36 months Due for at least one adolescent vaccine (HPV, MenACWY, Tdap) Exclusion Criteria: Primary care provider is not affiliated with Marshfield Clinic Health System Opted out of Marshfield Clinic Health System vaccine reminder notifications Missing or invalid contact information Deceased

Ages Eligible for Study
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Minimum Age: 12 Years
Maximum Age: 12 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Enhanced Reminder<br> | Behavioral: Reminder Sent Via Preferred Method of Communication<br>* Parents of 12 year-old patients due for ≥1 adolescent vaccine will receive a vaccine reminder notice every other month via their preferred method of communication (text message, email, mailed letter) until the adolescent receives all recommended vaccines, opts out of reminders, or turns 13.<br>|
| Other: Standard of Care<br> | Behavioral: Reminder Sent Via Mailed Letter<br>* Parents of 12 year-old patients due for ≥1 adolescent vaccine will receive a mailed vaccine reminder letter every other month until the adolescent receives all recommended vaccines, opts out of reminders, or turns 13.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of patients that received 1 dose of HPV vaccine during follow-up based on electronic health data | Receipt of 1 dose of HPV vaccine within 90 days of receipt of reminder (yes/no) will be assessed using vaccination data available from the Marshfield Clinic Health System electronic health record, which includes vaccinations administered outside of MCHS through data exchanges with the Wisconsin Immunization Registry. Specifically patients will be classified as having received 1 dose of HPV vaccine if they have record of receipt of HPV vaccine with a vaccination date during the 90-day follow-up period. | 90 days |