Effects of Continuous Venous Dialysis and Hemodialysis on Fluid Dynamics by Bioreactance Method

Study Overview
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Brief Summary
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Dialysis methods applied at the bedside and dialysis methods applied in hemodialysis unit are widely applied in patients with renal insufficiency. Especially hemodynamically affected patients are less affected by hemodynamics as a result of using dialysis methods. It is a completely non-invasive method by bioreactance method and it can be done to measure the intra-body fluid status with the help of the glued probes. The aim of this study is to investigate the effects of continuous venous dialysis and hemodialysis on the fluid dynamics applied at the bedside with bioreactance method. In this way, the patient can develop more comfortable hemodynamic changes. Patients in the Surgery, Reanimation and Postoperative Intensive Care Unit with more than 24 hours of hospitalization and bedside dialysis or hemodialysis will be included in the study. Before the dialysis, body fluid measurements will be made with bioreactance, and after dialysis in patients receiving hemodialysis, and in dialysis patients 6, 12, 24 and 36 hours.

Detailed Description
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Dialysis methods applied at the bedside and dialysis methods applied in hemodialysis unit are widely applied in patients with renal insufficiency. Especially hemodynamically affected patients are less affected by hemodynamics as a result of using dialysis methods. Dialysis in the hemodialysis unit is a method used in intensive care patients and is preferred especially in patients with stable hemodynamics. In dialysis methods, changes occur frequently in the body fluids of the patient. It is a completely non-invasive method by bioreactance method and it can be done to measure the intra-body fluid status with the help of the glued probes. The aim of this study is to investigate the effects of continuous venous dialysis and hemodialysis on the fluid dynamics applied at the bedside with bioreactance method. As a result of measurements with buioreactans method, fluid balance in patients will be understood more easily. In this way, the patient can develop more comfortable hemodynamic changes. Patients in the Surgery, Reanimation and Postoperative Intensive Care Unit with more than 24 hours of hospitalization and bedside dialysis or hemodialysis will be included in the study. Before the dialysis, body fluid measurements will be made with bioreactance, and after dialysis in patients receiving hemodialysis, and in dialysis patients 6, 12, 24 and 36 hours.

Official Title
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Investigation of the Effects of Continuous Venous Dialysis and Hemodialysis on Fluid Dynamics by Bioreactance Method

Conditions
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Renal Dialysis

Intervention / Treatment
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* Device: bioreactans tool


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients required dialysis therapy Exclusion Criteria: under 18 years old confirmed or undiagnosed brain death

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 90 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| continous veno-venous hemodialysis<br>to measure the fluid changes by using bioreactance method in continous veno-venous hemodialysis group | Device: bioreactans tool<br>* It is a completely non-invasive method by bioreactance method and it can be done to measure the intra-body fluid status with the help of the probes.<br>|
| hemodialysis<br>to measure the fluid changes by using bioreactance method in hemodialysis group | Device: bioreactans tool<br>* It is a completely non-invasive method by bioreactance method and it can be done to measure the intra-body fluid status with the help of the probes.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| change in thoracic fluid content | change in thoracic fluid content | before and after hemodialysis therapy, before bedside continous venovenous dialysis therapy and 6,12,24 and 36. hours | 
| change in Cardiac Output | change in Cardiac Output | before and after hemodialysis therapy, before bedside continous venovenous dialysis therapy and 6,12,24 and 36. hours | 
| change in Cardiac Index | change in Cardiac Index | before and after hemodialysis therapy, before bedside continous venovenous dialysis therapy and 6,12,24 and 36. hours | 
| change in stroke volum | change in stroke volum | before and after hemodialysis therapy, before bedside continous venovenous dialysis therapy and 6,12,24 and 36. hours |