Performance Evaluation of a 3D PSIR Sequence in MRI at 1.5T

Study Overview
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Brief Summary
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Inclusion visit (D0): verification of inclusion and non-inclusion criteria information and collection of consent standard imaging protocol prescribed as part of the usual treatment: sagittal T1 and T2 slices after injection of contrast product (Gadolinium), o 3D STIR sequence. 3D PSIR sequence at the level of the cervical cord for the duration of the additional sequence is 10 minutes, for a total examination time of 45 minutes (instead of 35 minutes).

Official Title
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Performance Evaluation of a 3D PSIR Sequence in MRI at 1.5T in the Detection and Characterization of Spinal Cord Injuries in Patients With Multiple Sclerosis

Conditions
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Multiple Sclerosis

Intervention / Treatment
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* Device: MRI 1.5 tesla


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patient over 18 years old To benefit from a medullary exploration planned by MRI 1.5T as part of a first evaluation or a re-evaluation of inflammatory involvement of the nevrax Express consent to participate in the study Affiliate or beneficiary of a social security scheme Exclusion Criteria: Patient benefiting from a legal protection measure Pregnant, parturient or breastfeeding woman Absolute or relative contraindication to MRI

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Device: MRI 1.5 tesla|standard imaging protocol prescribed as part of the usual treatment: sagittal T1 and T2 slices after injection of contrast product (Gadolinium), o 3D STIR sequence. 3D PSIR sequence at the level of the cervical cord for the duration of the additional sequence is 10 minutes, for a total examination time of 45 minutes (instead of 35 minutes)|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Estimate the number of spinal cord injuries detected with the set of standard sequences (T1, T2 and STIR) that are not detected with the 3D PSIR sequence |  | 1 DAY | 
| Estimate the number of active lesions taking the contrast after injection of gadolinium, with the 3D PSIR sequence which is not detected in the set of standard sequences (T1, T2 and STIR) |  | 1 day | 
| Compare the diagnostic confidence expressed by the radiologist for the detection of spinal cord injuries with the 3D PSIR sequence compared to the set of standard sequences (T1, T2 and STIR) |  | 1 DAY | 
| Describe the quality of the images in terms of artifacts for each of the sequences used (T1, T2, STIR and PSIR) |  | 1 DAY | 
| Measure the signal-to-noise ratio of each of the sequences used (T1, T2, STIR and PSIR) |  | 1 DAY | 
| Measure the inter-observer agreement on the number of lesions detected with the 3D PSIR sequence |  | 1 DAY | 
| Measure the intra-observer agreement on the number of lesions detected with the 3D PSIR sequence |  | 1 DAY |