Influence of Diet and Lifestyle Factors on the Results of the IVF

Study Overview
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Brief Summary
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The purpose of this study is study the possible relationship between various lifestyle habits of men and women (age, body mass index, diet, exercise, alcohol, tobacco, coffee, etc..) and live birth rate after in vitro fertilization-intracytoplasmatic injection (IVF-ICSI).

Detailed Description
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It is a prospective study of couples with primary or secondary infertility, with indication for IVF. The main objective is to relate different lifestyle factors (age, BMI, physical activity, tobacco consumption, alchol, drugs, work and diet) with reproductive outcomes obtained in terms of total oocytes, M II, fertilization and implantation rates pregnancy and abortion rates and live birth. It also attempts to correlate the different habits of life in men with seminal parameters. For this, both members of the pair separately should answer a validated questionnaire before beginning the therapeutic process.

Official Title
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Pilot Study on the Influence of the Different Components of the Diet and Different Habits (Tobacco, Alcohol, Physical Exercise, Occupation) Results of IVF-ICSI

Conditions
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Lifestyle Factors

Intervention / Treatment
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* Other: Questionnaire


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Couples who want a pregnancy Mediterranean or Caucasian Ethnicity. Infertility to justify treatment with IVF / ICSI-TEI. First cycle of IVF / ICSI. Between 18 and 37 years (inclusive) Presence of one or both ovaries and uterus can withstand embryo implantation and pregnancy. Body mass index (BMI) <40. Absence of pregnancy before starting ovarian stimulation. Having given their written consent. Exclusion Criteria: Clinically important disease. Inclusion in previous cycles of assisted reproduction. Unexplained vaginal bleeding. Any contraindication to become pregnant. Known allergy to preparations of gonadotropins or its excipients. Patients undergoing oocyte donation cycles -

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 37 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Couples with indication for IVF<br>Couples with primary or secondary infertility with indication of IVF | Other: Questionnaire<br>* Questionnaire with 100 questions divided into different groups: general data, work, physical activity, character, hobbies, disease and diet.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Live birth rate |  | One year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pregnancy rate |  | 1 month | 
| Number of mature oocytes |  | Two weeks | 
| Fertilization rate |  | Two weeks | 
| Cancelation rate |  | One month | 
| Total dose | Total dose of gonadotrophins needed to stimulate the follicular growth | One month | 
| Total Sperm count | Total number of spermatozoa in the seminal and number of spermatozoa/ml | Two weeks | 
| Abortion rate |  | 16 weeks | 
| Hyperstimulation rate | Moderate and severe hyperstimulation | One month |