Penetrating Abdominal Injuries From the Battle of Mosul

Study Overview
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Brief Summary
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The battle of Mosul was characterized by the use of improvised explosive devices, human shields and suicide bombers in an urban setting. It is unclear whether this type of warfare cause more extensive abdominal injuries to civilians than combatants. All patients admitted with penetrating abdominal injury subjected to an exploratory laparotomy at Emergency Hospital, Erbil, between October 17, 2016 and July 16, 2017 will be included. Differences in demographics, injury mechanism, time since injury, clinical status on arrival, intraoperative findings, postoperative complications and outcome will be studied.

Detailed Description
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Study Rationale The battle of Mosul was characterized by the use of improvised explosive devices, human shields and suicide bombers in an urban setting. It is unclear whether this type of warfare cause more extensive abdominal injuries to civilians than combatants. Understanding of the correlation between the severity of abdominal injuries, type of warfare and population affected is of importance when planning for surgical care in a conflict setting. Aim To assess whether civilians obtain more extensive abdominal injuries than combatants in an urban battle characterized by the use of indiscriminate weapons. Study Design An observational retrospective cohort study with longitudinal data collection. All patients admitted with penetrating abdominal injury subjected to an exploratory laparotomy at Emergency Hospital, Erbil, between October 17, 2016 and July 16, 2017 will be included. Differences in demographics, injury mechanism, time since injury, clinical status on arrival, intraoperative findings, postoperative complications and outcome will be analysed. Primary Objective Differences in injury mechanism, organs injured, surgical treatment given, postoperative complications and outcome between civilians and combatants. Secondary Objectives Differences in surgical treatment given, postoperative complications and outcome between patients with prior surgical treatment of their injury and patients without prior surgical treatment. Differences in surgical treatment given, postoperative complications and outcome between patients who receive surgical treatment less than 24 hours from injury and patients who receive surgical treatment more than 24 hours from injury will be analysed. Statistical methods Differences between groups will be analysed using t-test and regression models.

Official Title
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Exploratory Laparotomy Following Penetrating Abdominal Injuries From the Battle of Mosul: a Cohort Study From a Referral Hospital in Erbil, Kurdistan Region in Iraq

Conditions
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Penetrating Abdominal Trauma, War Injury

Intervention / Treatment
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* Procedure: Exploratory laparotomy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria (all must be fulfilled): Penetrating abdominal injury Subjected to an exploratory laparotomy at Emergency Hospital, Erbil, Iraq Between October 17, 2016 and July 16, 2017 Exclusion Criteria (all must be fulfilled): Patients who received treatment several times will only be counted as one patient Between October 17, 2016 and July 16, 2017
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Combatants<br>Men 16-50 years old or combatants by own admission. | Procedure: Exploratory laparotomy<br>* Findings and procedures done at exploratory laparotomy<br>|
| Civilians<br>Children <16 years, all women and men ≥50 years. | Procedure: Exploratory laparotomy<br>* Findings and procedures done at exploratory laparotomy<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Differences in injury mechanism, organs injured, surgical treatment given, postoperative complications and outcome between civilians and combatants. |  | an average of 3 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Differences in surgical treatment given, postoperative complications and outcome between patients with prior surgical treatment of their injury and patients without prior surgical treatment. |  | an average of 3 weeks | 
| Differences in surgical treatment given, postoperative complications and outcome between patients who receive surgical treatment less than 24 hours from injury and patients who receive surgical treatment more than 24 hours from injury will be analysed. |  | an average of 3 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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War injury, Penetrating abdominal trauma, Exploratory laparotomy, Improvised explosive device, Mosul