Prevalence of Iodine Deficiency in Remote Communities of Haiti

Study Overview
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Brief Summary
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Haiti is one of the few remaining countries that is at risk of iodine deficiency disorders. In the 2018 survey, iodized salt was found in <20% of households and iodine excretion from non-pregnant and pregnant women suggested inadequate intakes, with those in remote inland settings most at risk. The Haiti Salt Program (HSP) was established in 2006 at the University of Notre Dame, US (UND). Using a self-sustaining business model that protects the livelihoods of all who work within it, the HSP has a goal of supplying fortified salt to combat IDD and lymphatic filariasis. HSP purchases salt from local small producers for processing in a local factory equipped with robust, standardized and controlled facilities that iodizes the salt under correct conditions, ready for fair resale to the consumer. The salt is currently distributed in the West Department, though a country-wide roll-out is envisaged. This initiative has the potential to accelerate optimization of population iodine intake across Haiti and through IDD prevention, positively contributing to the development of the country. Data on iodine status and intake of native iodine-rich foods, iodized salt and other iodine-fortified foods e.g., bouillon cubes in Haiti, are sparse, particularly from rural and remote locations. An update on the situation in such remote areas in Haiti is trequired, to inform and leverage the development and implementation of iodized salt policy in the region. The specific objective of this study is to assess the iodine status of two representative population subgroups, namely school-age children and women of reproductive age, in a remote region of the Central Plateau of Haiti. We hypothesize that the mUIC will indicate population iodine insufficiency in both of these population groups.

Official Title
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Assessing the Prevalence of Iodine Deficiency in Remote Communities of the Central Plateau, Haiti: a Cross-sectional Study (ARCH)

Conditions
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Iodine Deficiency

Intervention / Treatment
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* Other: No intervention


Participation Criteria
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Eligibility Criteria
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We will recruit school age children (male and female, aged 9-13 years) and women of reproductive age (aged 18-44 years). The inclusion criteria for all subjects will be: residence within the study area for ≥12 months; general good health as assessed by no reported treatment for chronic disease; no known history of goiter or other thyroid disease; no exposure to iodine containing contrast agent or medication within the last year; Women of reproductive age should not currently be pregnant or be breastfeeding, assessed by asking the women.

Ages Eligible for Study
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Minimum Age: 9 Years
Maximum Age: 44 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| School age children aged 9-13 years<br> | Other: No intervention<br>* No intervention<br>|
| Women of reproductive age aged 18-44 years<br> | Other: No intervention<br>* No intervention<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Urinary iodine concentration | iodine measured in a spot sample of urine | through study completion, estimated 2 to 3 months |