Bone Microarchitecture in Women Practicing Golf

Study Overview
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Brief Summary
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After the age of 50, one in three women and one in eight men will experience at least one fragility fracture during the rest of their lives. It is currently recognized that physical activity has an osteogenic actions, especially when it includes the impact transmitted to the skeleton. In this context, the investigators propose a study to determine whether the regular practice of golf could be particularly beneficial for the skeleton, not only in the lower limbs, due to repeated impacts to the ground when it requires sustained walking, but also the upper limbs due to the impacts transmitted by the club at the time of striking the ball, as has been amply demonstrated with racquet sports.

Detailed Description
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Each patient will have 1 blood samples and 1 measure of bone by 3D micro-tomography (3D CT Scan).These examinations and sampling will take place on 1 day.

Official Title
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Is Golf a Sport Suited to the Female Skeleton After 60 Years? Pilot Study Evaluating the Microarchitecture 3D Carriers and Noncarriers Bones

Conditions
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Bone Microarchitecture

Intervention / Treatment
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* Other: 3D CT scan


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Golfers: Regular playing golf for over 2 years at 8 to 12 hours per week recruited into golf clubs. Walkers: regular practice of walking for over 2 years at 8 to 12 hours per week recruited into the walking clubs. Sedentary: no intensive physical activity (<2 hours / week), recruited in clubs seniors. Exclusion Criteria: concomitant bone disease , Hip prosthesis the dominant side Endocrinopathy hypercalcemia, vitamin D deficiency, hypo- or hyper calciuria Active smoking (more than 5 cigarettes / day), chronic alcoholism, Treatments received in the previous six months and resounding on bone metabolism such growth promoters, all osteoporosis, corticosteroids.

Ages Eligible for Study
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Minimum Age: 60 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Subject practicing golf and accept bone measure<br>Each patient will have 1 blood sample and 1 measure of bone by 3D micro-tomography | Other: 3D CT scan<br>* Measure of bone micro-architecture by 3D micro-tomography<br>|
| Subject practicing foot walk and accept bone measure<br>Each patient will have 1 blood sample and 1 measure of bone by 3D micro-tomography | Other: 3D CT scan<br>* Measure of bone micro-architecture by 3D micro-tomography<br>|
| Subject sedentary and accept bone measure<br>Each patient will have 1 blood sample and 1 measure of bone by 3D micro-tomography | Other: 3D CT scan<br>* Measure of bone micro-architecture by 3D micro-tomography<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bone volume / tissue volume | Measure of Bone volume / tissue volume by the 3D CT scan | day 1 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Bone microarchitecture, Playing golf, Walkers