Fall Prevention in Elderly: Mechanisms and Strategies

Study Overview
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Brief Summary
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In communities with over 100,000 residents, to investigate the incidence and mechanisms of fall in elderly, and strategies of fall prevention.

Official Title
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STrategies and mechAnisms of Community-Based falL Prevention in Elderly

Conditions
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Elderly

Intervention / Treatment
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* Behavioral: Exercise


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: community dwelling adults without medical conditions to impair walking ability Exclusion Criteria: cognitively or physically unable to cooperate with the examiner to finish the test

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Allocation: Non-Randomized
Intervention Model: Factorial Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Elderly without fall history<br>Elderly people in the community who have no fall history | Behavioral: Exercise<br>* Elderly people with or without fall history receive exercise to improve balance. Exercise interevention will be given 6 months in 2020. Outcomes (incidence of fall and biological tests) between two arms will be compared.<br>|
| Other: Elderly with fall history<br>Elderly people in the community who have fall history | Behavioral: Exercise<br>* Elderly people with or without fall history receive exercise to improve balance. Exercise interevention will be given 6 months in 2020. Outcomes (incidence of fall and biological tests) between two arms will be compared.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of fall | Incidence of fall each year | From date of recruitment until the end of the study, assessed up to 42 months (reported once per year) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Kinematics test | During balance tests, assessing kinematics by using inertia sensors. | From date of recruitment until the end of the study, assessed up to 42 months | 
| Kinetics test | During balance tests, assessing kinetics by using sEMG (high-density surface EMG). | From date of recruitment until the end of the study, assessed up to 42 months | 
| EEG test | During balance tests, assessing brain mechanisms by using electroencephalogram (EEG). | From date of recruitment until the end of the study, assessed up to 42 months | 
| fNIRS test | During balance tests, assessing brain mechanisms by using functional near-infrared spectroscopy (fNIRS). | From date of recruitment until the end of the study, assessed up to 42 months | 
| MRI assessments | Using functional magnetic resonance imaging to assess brain mechanisms during foot movements. | From date of recruitment until the end of the study, assessed up to 42 months |