Balance After Knee Arthroplasty

Study Overview
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Brief Summary
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Evaluation of patients before and after knee arthroplasty regarding balance, function and quality of life. Comparison of total and unicompartmental knee arthroplasty. Comparison of the primary outcome parameter and selected secondary outcome parameters to healthy controls.

Official Title
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Assessment of Balance, Function and Quality of Life in Patients Before and After Knee Replacement

Conditions
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Postural Balance, Knee Arthroplasty, Quality of Life

Intervention / Treatment
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* Procedure: Knee Arthroplasty


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Primary gonarthrosis planned TKA or UKA adequate cognitive and lingual competence informed consent Exclusion Criteria: TKA or UKA revision Surgery after trauma Rheumatic disease Neurologic disease previous arthroplasty of the lower extremity (<9 months) cardiovascular disease restricted weight bearing of the lower extremity after surgery

Ages Eligible for Study
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Minimum Age: 55 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Total Knee Arthroplasty (TKA)<br>Patients intended to undergo surgery for total knee arthroplasty | Procedure: Knee Arthroplasty<br>* Comparison of TKA, UKA and healthy controls in relation to balance, function and QOL<br>|
| Active Comparator: Unicompartmental Knee Arthroplasty (UKA)<br>Patients intended to undergo surgery for unicompartmental knee arthroplasty | Procedure: Knee Arthroplasty<br>* Comparison of TKA, UKA and healthy controls in relation to balance, function and QOL<br>|
| No Intervention: Healthy Control<br> | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Center of pressure track (COPT) | Posturographic Parameter | Before surgery | 
| Center of pressure track (COPT) | Posturographic Parameter | Day 3-7 after surgery | 
| Center of pressure track (COPT) | Posturographic Parameter | 3 months after surgery | 
| Center of pressure track (COPT) | Posturographic Parameter | 1 year after surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Functional reach test |  | Before surgery; day 3-7 after surgery; 3 months and 1 year after surgery | 
| Timed up and go - test |  | Before surgery; day 3-7 after surgery; 3 months and 1 year after surgery | 
| Knee Injury and Osteoarthritis Outcome Score | Scale: Points, Minimum: 0, Maximum: 100, higher score means better outcome | Before surgery; day 3-7 after surgery; 3 months and 1 year after surgery | 
| EQ-5D - Score | Scale: Points, Minimum: 1, Maximum: <0, higher score means better outcome | Before surgery; 1 year after surgery | 
| 10 m Walking test |  | Before surgery; day 3-7 after surgery; 3 months and 1 year after surgery | 
| WOMAC Score | Scale: Points, Minimum: 0, Maximum: 240, higher score means worse outcome | Before surgery; 1 year after surgery, higher score means better outcome | 
| Forgotten Joint Score | Scale: Points, Minimum: 0, Maximum: 100, higher score means better outcome | Before surgery; 1 year after surgery | 
| Oxford Knee Score | Scale: Points, Minimum: 12, Maximum: 60, higher score means worse outcome | Before surgery; 1 year after surgery | 
| Knee Society Score | Scale: Points, Minimum: 0, Maximum: 100, higher score means better outcome | Before surgery; 1 year after surgery | 
| The University of California at Los Angeles Activity Score | Scale: Points, Minimum: 1, Maximum: 10, higher score means better outcome | Before surgery; 1 year after surgery | 
| Area of Sway | Posturographic Parameter | Before surgery; day 3-7 after surgery; 3 months and 1 year after surgery | 
| Frequency of Sway | Posturographic Parameter | Before surgery; day 3-7 after surgery; 3 months and 1 year after surgery | 
| Harmony Index | Posturographic Parameter | Before surgery; day 3-7 after surgery; 3 months and 1 year after surgery | 
| Stability energy | Posturographic Parameter | Before surgery; day 3-7 after surgery; 3 months and 1 year after surgery | 
| Movement control | Posturographic Parameter | Before surgery; day 3-7 after surgery; 3 months and 1 year after surgery | 
| Feedback (visual, somatosensoric, vestibular) | Posturographic Parameter | Before surgery; day 3-7 after surgery; 3 months and 1 year after surgery | 
| Weight Distribution Index | Posturographic Parameter | Before surgery; day 3-7 after surgery; 3 months and 1 year after surgery | 
| Fulfillment of Tests | Posturographic Parameter | Before surgery; day 3-7 after surgery; 3 months and 1 year after surgery |