Functional and Morphological Results of Rhegmatogenous Retinal Detachment Treated With Vitrectomy

Study Overview
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Brief Summary
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To examine morphological and functional results after pars plana vitrectomy (PPV) with SF6 gas tamponade due to macula-on and macula-off rhegmatogenous retinal detachment (RRD) during six months of the follow-up.

Detailed Description
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Background: To examine morphological and functional results after pars plana vitrectomy (PPV) with SF6 gas tamponade due to macula-on and macula-off rhegmatogenous retinal detachment (RRD) during six months of the follow-up. Methods: The study included 62 eyes that underwent successful PPV with SF6 tamponade with macula-on (34 eyes) and macula-off (28 eyes) RRD preoperatively. The best-corrected visual acuity (BCVA), Amsler test, M-charts, optical coherence tomography (OCT) and microperimetry were performed at 1, 3 and 6 months postoperatively.

Official Title
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Functional and Morphological Results of macula-on and Macula-off Rhegmatogenous Retinal Detachment Treated With Pars Plana Vitrectomy and Sulfur Hexafluoride Gas Tamponade

Conditions
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Retinal Detachment, Vitrectomy

Intervention / Treatment
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* Diagnostic Test: Microperimetry
* Diagnostic Test: M-charts


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: The diagnosed macula-on and macula-off rhegmatogenous retinal detachment. Exclusion Criteria: history of uveitis, diabetic retinopathy, previous vitreoretinal surgery, glaucoma or eye trauma, retinal detachment combined with macular hole or proliferative vitreoretinopathy
Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Group of 62 eyes<br>Group of 62 eyes with rhegmatogenous retinal detachment who underwent successful vitrectomy with SF6 tamponade | Diagnostic Test: Microperimetry<br>* Microperimetry is a procedure to assess retinal sensitivity while fundus is directly examined; it enables exact correlation between macular pathology and corresponding functional abnormality.<br>Diagnostic Test: M-charts<br>* The M-chart (Inami Co., Tokyo, Japan) is a diagnostic tool developed by Matsumoto to quantify the degree of metamorphopsia in patients with macular diseases.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The best-corrected visual acuity (BCVA) | Acuity is a measure of visual performance. The eye exam seeks to find the prescription that will provide the best corrected visual performance achievable. | 1 to 6 months | 
| Amsler test | The standard Amsler test performs with black lines on the white background. The Amsler grid has been used so far for the qualitative assessment of the metamorphopsia since 1947. | 1 to 6 months | 
| M-charts | The M-charts consist of 19 dashed lines with increasing distance between points in the range of 0.2 ° to 2.0 ° viewing angle. Matsumoto developed M-charts for quantitative metamorphopsia evaluation in macula diseases in 1990. M-charts provide more information than Amsler chart in regard to the horizontal and vertical lines. | 1 to 6 months | 
| Central retinal thickness | Quantitative thickness measurements derived from the fast macular scan algorithm report retinal thickness at several locations including the center point, central subfield, and 4 inner and 4 outer zones of the macula. | 1 to 6 months | 
| Microperimetry | Microperimetry is a procedure to assess retinal sensitivity while fundus is directly examined; it enables exact correlation between macular pathology and corresponding functional abnormality. | 1 to 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Rhegmatogenous retinal detachment, Vitrectomy, Metamorphopsia, M-charts, Microperimetry