Observational Study Evaluating the Use of Intellivent® for Patients With Respiratory Distress Syndrome

Study Overview
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Brief Summary
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Rational: Intellivent is a ventilation mode completely automated which controls ventilation and oxygenation parameters. Safety and performance of IntelliVent has still been demonstrated in post operative heart surgery for patient with a controlled ventilation on short period (2 to 4 hours). This feasibility study evaluate the use of Intellivent for Intensive care unit patients from intubation to coming off. Primary objective : Compare parameters which have been selected by automated mod (Intellivent) to those selected by clinical practitioner in a conventional mode Secondary objectives: Record oxygenation , gaseous interchange and ventilation parameters. Record complications, number of manual adjustments and prognostic signs. Methodology: Patients in the intensive care unit who need invasive ventilation. They will be included after a detailed information (information note). Oxygenation and ventilation parameters will be recorded 2 times by day from intubation to coming off. The investigator in charge will determine daily at the bedside of the patient the adjustments he should make in a conventional mode. These adjustments will be compared to the IntelliVent automated adjustments. Experimental study, observational, prospective, comparative, opened, monocentric in an intensive care unit. Number of patients: 100

Official Title
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Etude Clinique Observationnelle, Prospective, Ouverte, Monocentrique Sur l'Utilisation d'un Mode Ventilatoire entièrement automatisé Chez Les Patients de réanimation de l'Intubation Jusqu'au Sevrage.

Conditions
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Respiratory Distress Syndrome

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patient which needs an invasive ventilation Intubation < 24 hours Age ≥ 18 years Exclusion Criteria: Patient which has withdrawal standard in line with the unit coming off procedure (all criteria must be present) temperature ≤ 38,5°C No pressor drug No sedation, Motor response to order, Cough during bronchoaspiration %VM ≤ 130%, FiO2 ≤ 50%, PEEP ≤ 5 cmH2O, Pinsp ≤ 25 cmH2O. Patient with non invasive ventilation . Dysfunctions of the ventilatory command (ex Cheyne-Stokes). Broncho pleural fistula. Brain dead status. Pregnant woman. Adult under guardianship. Person deprived of liberty

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| oxygenation , gaseous interchange and ventilation parameters | Record oxygenation , gaseous interchange and ventilation parameters | Participants are followed until they no longer need ventilation up to 10 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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ventilation, automated