Detecting the Changes of Swallowing Function in Tongue Cancer Patients Receiving Mandibular-lip Split or Pull-through Resection Surgeries

Study Overview
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Brief Summary
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The evidence of swallowing changes in tongue cancer patients receiving mandibular-lip split or pull-through resection surgeries is still limited. This study aimed to investigated the swallowing changes in these patients by using the videofluoroscopy (VFSS) and high resolution impedance manometry (HRIM).

Detailed Description
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Objective: to investigated the swallowing changes in these patients receiving mandibular-lip split or pull-through resection surgeries by using the videofluoroscopy (VFSS) and high resolution impedance manometry (HRIM). Methods: 1. patients are fulfilled elective mandibular-lip split or pull-through resection surgeries; 2. they all received VFSS and HRIM exmination before surgery. 3. they were randomized into two groups (mandibular-lip split surgery or pull-through resection surgeries). 4. after receiving the surgery, the patients were followed the swallowing function at postoperative 1, 3, and 6 months. Anticipating results: the swallowing function at pull-through resection surgery has faster recovery than mandibular lip split methods.

Official Title
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Using High Resolution Impedance Manometry (HRIM) Combined With Videofluoroscopic Swallow Study (VFSS) to Investigate the Changes of Swallowing Function in Tongue Cancer Patients Receiving Mandibular-lip Split or Pull-through Resection Surgeries

Conditions
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Swallowing Function

Intervention / Treatment
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* Procedure: pull through group
* Procedure: mandibular-lip split group


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients elective received tongue cancer surgery and suitable to receive mandibular-lip split or pull-through resection surgeries Exclusion Criteria: 1. patients had major underlying disease, ex: heart, brain, lung, liver disease 2. coagulopathy 3.pregnancy 4. the patients could not have good compliance

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: pull through group<br>the patients receiving the pull though method during the tongue cancer surgery | Procedure: pull through group<br>* pull through method<br>|
| Placebo Comparator: mandibular-lip split group<br>the patients receiving the traditional mandibular lip split method during the tongue cancer surgery | Procedure: mandibular-lip split group<br>* traditional mandibular-lip split method<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| pharyngeal pressure | the contraction of pharyngeal muscle | 15 minutes during the examination postoperative 1 month |