Cognitive Behavioural Therapy for Obesity

Study Overview
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Brief Summary
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The purpose of this study is to evaluate the effectiveness of a cognitive behavioural treatment (CBT) designed to help obese patients lose weight and to maintain their weight losses over time. It is hypothesized that CBT will result in greater sustained weight loss.

Detailed Description
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The primary aim of the present study is to improve the maintenance of weight loss, and hence the physical, psychological and social well-being, of obese patients who have sought weight loss treatment. To do so, it will implement a cognitive-behavioural treatment (CBT) with motivational enhancement strategies specifically designed to target weight maintenance. It is hypothesized that the maintenance-oriented CBT approach will result in sustained weight loss, as well as improved physical, psychological and social well-being.

Official Title
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A Maintenance-Oriented Cognitive Behavioural Therapy in the Treatment of Obesity

Conditions
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Obesity

Intervention / Treatment
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* Behavioral: cognitive behavioural therapy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: The participants will be recruited from among patients referred to the Metabolism and Obesity Service of Royal Prince Alfred Hospital. The inclusion criteria include: 18-65 years of age and a body mass index (BMI: kg/m2) between 30-45. Exclusion Criteria: psychiatric conditions (i.e., current psychosis, severe depression, mental retardation, and drug or alcohol abuse) or physical conditions (i.e., significant hepatic or renal dysfunction and significant cardiovascular disease such as heart failure, stroke and transient ischaemic attacks) that would preclude full participation in the study; current treatment for obesity; current treatments known to affect eating or weight (e.g., medications); pregnancy.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: 1<br>20 weekly sessions of CBT integrated with motivational enhancement strategies | Behavioral: cognitive behavioural therapy<br>* 20 weekly sessions of CBT integrated with motivational enhancement strategies<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Weight |  | baseline, post-treatment, one-year follow-up | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| obesity-specific quality of life, mood disturbance, eating disturbance, cognitive disturbance |  | baseline, post-treatment, one-year follow-up | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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obesity, CBT, motivational enhancement therapy, weight loss maintenance