Efficacy of Antimicrobial Coating Suture Coated Vicryl Plus Compared With Vicryl in Reduced Surgical Site Infection of Dental Implant Surgeries: A Uni-Blind Randomized Clinical Trial Study

Study Overview
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Brief Summary
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Patients randomly aligned in 2 groups.Vicryl plus sutures were used in group 1 for closing subperiostal flaps after dental implant surgeries and vicryl sutures were used in group 2.

Detailed Description
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Patients were divided randomly based on computer randomization list in two groups: In group1, vicryl plus 4-0 (Vicryl Plus Ethicon,Johnson & Johnson Company, Sommerville, NJ) suture was used to close surgical site and Vicryl 4-0 (Vicryl Ethicon,Johnson & Johnson Company, Sommerville, NJ) in group II. All dental implants were placed through creating subperiosteal flaps. In each group, fresh socket placed dental implants were documented. Patients were visited in 1, 2, 3 and 4 weeks after dental implant surgeries. Postoperative infection was defined as local erythematous change in the sutured wound with purulent discharge or localized abscess formation on surgical site. If wound dehiscence occurred, it was documented. Patients were blind about what suture was used.

Official Title
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Vicryl Plus and Vicryl Sutures in Reduce of Infection in Dental Implant Surgery

Conditions
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Infection, Surgical Site

Intervention / Treatment
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* Drug: Vicryl plus


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Need 3 dental implants at the posterior of the mandible Exclusion Criteria: Diabetic patients smoker poor oral hygiene

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: In group1, vicryl plus suture was used to close flaps. In group2,vicryl was used to close flaps
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Vicryl plus<br>In this group, vicryl plus(Triclosan coated) sutures were used to close flaps | Drug: Vicryl plus<br>* Using vicryl sutures which coated with triclosan (antibiotic)<br>|
| No Intervention: vicryl<br>In this group, vicryl sutures were used to close flaps | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The prevalence of post-operative infection | The number of participants who had local erythematous change in the sutured wound with purulent discharge or localized abscess formation on surgical site. | In one month | 
| The prevalence of post-operative dehiscence | The number of participants who had relatively or completely open wound | In one month | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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sutures, Surgical Wound Infection, Polyglactin 910