Postoperative Cognitive Dysfunction in Heart Surgery

Study Overview
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Brief Summary
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To determine the rate of Postoperative Cognitive Dysfunction (POCD) in the early and late postoperative periods by comparing the preop and postop period mini mental status tests in participants undergoing open heart surgery, and to compare the results of the investgators clinic with the world literature.

Detailed Description
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Postoperative delirium (POD) and Cognitive Dysfunction (POCD) are changes in mental status, especially in the geriatric surgery population.Unlike other forms of delirium, POD results in early full recovery.Postoperative Cognitive Dysfunction (POCD) is more difficult to define and implies temporal consciousness impairment associated with surgery. While the diagnosis of delirium requires the detection of symptoms, the diagnosis of POCD requires preoperative neuropsychological testing and determining how much reduction will mean cognitive dysfunction. Postoperative delirium management is complex and requires multiple strategies. Methods of treating and preventing POCD are still uncertain.It is known that POCD is most commonly seen in patients undergoing open heart surgery.In this study, the investigators aim is to evaluate whether there is any change in cognitive status in the postoperative period compared to the preoperative period of participants who will undergo open heart surgery due to valve pathology or coronary stenosis.

Official Title
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Postoperative Cognitive Dysfunction in Participants Undergoing Open Heart Surgery

Conditions
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Postoperative Cognitive Dysfunction

Intervention / Treatment
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* Other: Preoperative cognitive functions of participants undergoing open heart surgery
* Other: Postoperative cognitive functions of particiants undergoing open heart surgery


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 18-75 age American Society of Anesthesiologists (ASA) II-III Exclusion Criteria: >75 age <18 age Patients who died within 48 hours after the operation

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Preoperative cognitive status of participants undergoing open heart surgery<br>Detection of postoperative cognitive impairment is difficult and it starts with testing in the preoperative period. In this study, it was aimed to determine postoperative cognitive impairment by comparing cognitive functions by using Minimental status test in the preoperative period in participants scheduled for open heart surgery for one year. It was planned to compare the obtained data in terms of participants undergoing valve and coronary bypass surgery, age, gender, diabetes, kidney disease, chronic obstructive pulmonary disease (COPD), surgical characteristics, bypass time, and crossclamping time. | Other: Preoperative cognitive functions of participants undergoing open heart surgery<br>* Surgery times and cross-clamping times of the participants who will undergo open heart surgery were recorded.<br>|
| Postoperative cognitive status of participants undergoing open heart surgery<br>Detection of postoperative cognitive impairment is difficult and it starts with testing in the preoperative period. In this study, it was aimed to determine the postoperative cognitive impairment by comparing it with the cognitive functions in the preoperative period using the Minimental status test in the postoperative period in participants scheduled for open heart surgery for a year. It was planned to compare the obtained data in terms of participants undergoing valve and coronary bypass surgery, age, gender, diabetes, kidney disease, chronic obstructive pulmonary disease (COPD), surgical characteristics, bypass time, and crossclamping time. | Other: Postoperative cognitive functions of particiants undergoing open heart surgery<br>* Changes in mini mental test scores were recorded in the postoperative period.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluation of postoperative cognitive functions in participants undergoing open heart surgery. | The aim is to understand whether there is a loss of cognitive functions in the postoperative period, according to the preoperative periods, by testing the participants with open heart surgery on the 3rd day, 7th day, and 2nd month after the surgery. | 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Comparison with the literature. | Comparison of the results in the investigators clinic with the literature. | 1 year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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COGNITIVE DYSFUNCTİON, HEART SURGERY, POSTOPERATIVE DELIRIUM