Impact of Respiratory Rehabilitation on Quality of Life in Patients With Hyperventilation Syndrome

Study Overview
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Brief Summary
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The hyperventilation syndrome is a quite frequent pathology, affecting up to 10% of the general population and 40% of the asthmatic population. Its physiopathology is still badly known and even if it is a benign affection, its associated comorbidities and symptomatology greatly decrease the patients' quality of life. Yet, no medicinal treatments have been proved useful, but prescribers noticed improvements after physiotherapy. Given that the physiotherapy impact on hyperventilation syndrome is not well described in the literature, this study aims to scientifically ascertain physiotherapy benefits on quality of life and symptomatology in hyperventilation syndrome-suffering patients.

Official Title
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Impact of Respiratory Rehabilitation on Quality of Life, Measures by the SF-36 Score, in Patients With Hyperventilation Syndrome: Crossover, Prospective and Randomized Study

Conditions
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Hyperventilation Syndrome

Intervention / Treatment
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* Other: Respiratory rehabilitation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Positive hyperventilation syndrome diagnosis Having a social security insurance Being at least 18 years old Having given their written consent Exclusion Criteria: Being put under guardianship or curatorship Having seen a physiotherapist for a respiratory rehabilitation in the last three months Suffering from a chronic and degenerative pathology (chronic obstructive pulmonary disease, Parkinson's disease, idiopathic fibrosis, …) Not being able to receive the respiratory rehabilitation from our care providers Already having received a rehabilitation for hyperventilation syndrome Not speaking French or not being unable to complete the questionnaires

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Crossover Assignment
Interventional Model Description: Patients will be divided into two groups: Group 1 (Control Group) will not immediately receive respiratory rehabilitation but between the 2nd and 4th months postdiagnosis. Group 2 (Intervention Group) will immediately receive rehabilitation between the diagnosis and the 2nd month postdiagnosis.
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Control group<br>Group 1 (Control Group) will not immediately receive respiratory rehabilitation but between the 2nd and 4th months postdiagnosis. | Other: Respiratory rehabilitation<br>* Respiratory rehabilitation includes education, hypoventilation exercises, diaphragmatic breathing exercises, relaxation, retraining, others.<br>|
| Other: Intervention group<br>Group 2 (Intervention Group) will immediately receive rehabilitation between the diagnosis and the 2nd month postdiagnosis. | Other: Respiratory rehabilitation<br>* Respiratory rehabilitation includes education, hypoventilation exercises, diaphragmatic breathing exercises, relaxation, retraining, others.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of respiratory rehabilitation on Quality of life | Quality of life will be evaluated with the SF-36 score | Day 0 | 
| Incidence of respiratory rehabilitation on Quality of life | Quality of life will be evaluated with the SF-36 score | Month 2 | 
| Incidence of respiratory rehabilitation on Quality of life | Quality of life will be evaluated with the SF-36 score | Month 4 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in symptomatology | Change in symptomatology will be evaluated on the Nijmegen questionnaire | Day 0 | 
| Change in symptomatology | Change in symptomatology will be evaluated on the Nijmegen questionnaire | Month 2 | 
| Change in symptomatology | Change in symptomatology will be evaluated on the Nijmegen questionnaire | Month 4 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Hyperventilation syndrome, Respiratory rehabilitation, Quality of Life