The Impact of Diet Liberalization on Bowel Preparation for Colonoscopy

Study Overview
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Brief Summary
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This study will evaluate the expansion of dietary options from clear liquids the entire day to a low reside breakfast and lunch for patients prior to undergoing bowel preparation with MoviPrep® and its effect on preparation quality for colonoscopy.

Detailed Description
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This study will evaluate the expansion of dietary options from clear liquids the entire day to a low reside breakfast and lunch for patients prior to undergoing bowel preparation with MoviPrep® and its effect on preparation quality for colonoscopy. MoviPrep® is a commercially available 2 liter bowel purgative for use before colonoscopy in adults 18 years of age or older that is comprised of polyethylene glycol-electrolyte solution (PEG-ELS) plus sodium sulfate, sodium ascorbate, and ascorbic acid.

Official Title
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The Impact of Diet Liberalization on Bowel Preparation for Colonoscopy

Conditions
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Colonic Diseases

Intervention / Treatment
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* Other: Clear liquids
* Other: Low residue breakfast and lunch


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Elective outpatients > 18 yrs undergoing colonoscopy Exclusion Criteria: Unable or unwilling to give informed consent Age < 18 years Pregnant Breast feeding Gastroparesis - established or suspected Pseudo-obstruction - established or suspected Severe constipation (< 1 BM a week) Bowel obstruction Colon resection Chronic nausea or vomiting Known Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency PEG allergy Significant psychiatric illness

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: clear liquids<br>Clear liquids the day of bowel preparation up to 2.5 hrs before colonoscopy | Other: Clear liquids<br>* Clear liquids<br>|
| Active Comparator: low residue diet<br>Low residue breakfast and lunch up to 1pm; clear liquids thereafter up to 2.5 hrs before colonoscopy | Other: Low residue breakfast and lunch<br>* Low residue<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Efficacy - Overall bowel cleansing based on Boston Bowel Preparation Scale score BBPS score of 2-3 for each segment AND total score |  | 1 day (At colonoscopy) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Efficacy - Individual colon segment cleansing Successful cleansing defined as BBPS score of 2 - 3 for a segment |  | 1 day (At colonoscopy) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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colonoscopy