The Effect of the Sexual Abstinence Period on the Production of Reactive Oxygen Species in Patients Who Planned to Take Part in Intrauterine Insemination

Study Overview
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Brief Summary
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To determine the ideal sexual abstinence time for producing high quality sperm

Conditions
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Oxidative Stress

Intervention / Treatment
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* Behavioral: sexual abstinence


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients who had made an application to Gazi University Obstetrics and Gynecology clinic for infertility and planned to have IUI (intrauterine insemination) Exclusion Criteria: Erectile dysfunction- improper semen collection
Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: sexual abstinence period group I<br>The subjects participated in the study are divided into three groups according to the male partners sexual abstinence period during the day of sperm preparation for intrauterine insemination. Group I male partners have sexual abstinence period of 2 days or less. | Behavioral: sexual abstinence<br>* The subjects participated in the study are divided into three groups according to the male partners sexual abstinence period during the day of sperm preparation for intrauterine insemination.<br>|
| Active Comparator: sexual abstinence period group II<br>The subjects participated in the study are divided into three groups according to the male partners sexual abstinence period during the day of sperm preparation for intrauterine insemination. Group II male partners have sexual abstinence period of 2 to 4 days. | Behavioral: sexual abstinence<br>* The subjects participated in the study are divided into three groups according to the male partners sexual abstinence period during the day of sperm preparation for intrauterine insemination.<br>|
| Active Comparator: sexual abstinence period group III<br>The subjects participated in the study are divided into three groups according to the male partners sexual abstinence period during the day of sperm preparation for intrauterine insemination. Group II male partners have sexual abstinence period of more than 4 days | Behavioral: sexual abstinence<br>* The subjects participated in the study are divided into three groups according to the male partners sexual abstinence period during the day of sperm preparation for intrauterine insemination.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Effect of sexual abstinence period on oxidative stress status of seminal plasma collected for homologous artificial insemination | The study population is grouped according to the husbands sexual abstinence period before the time of sperm collection for homologous artificial insemination as 0-2 days vs 2-4 days vs 4-6 days | 0-2 days vs 2-4 days vs 4-6 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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sperm, oxidative stress, sexual abstinence