Effect of Washing With Clove Extract on Inflammation and Infection Place Logging Shaldon Needle

Study Overview
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Brief Summary
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This randomized clinical trial will conducted involving 60 patients under hemodialysis and hospitalized to Imam Reza and Montasareyeh hospitals of Mashhad in 2016. Patients were assigned to experimental and control groups of 30 people, randomly (double block). In the both intervention and control group, first will be washed the Catheter with Betadine, but in intervention group, after 2 minutes will be used of the clove extract with 2 ml of scrub for 15 seconds. The incidence and severity of inflammation as well as infection of vascular access will be assessed in patients on hemodialysis for each patient before starting the process over a period of 2 weeks is equivalent to 6 sessions of hemodialysis.

Detailed Description
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This study is a randomized clinical trial that will conducted on 60 patients under hemodialysis and hospitalized to Imam Reza and Montasareyeh hospitals of Mashhad in 2016. Patients were assigned to experimental and control groups of 30 people, randomly (double block). In the both intervention and control group, first will be washed the shaldon catheter with Betadine, but in intervention group, after 2 minutes will be used of the clove extract with 2 ml of scrub for 15 seconds. The incidence and severity of inflammation as well as infection of vascular access will be assessed in patients on hemodialysis for each patient before starting the process over a period of 2 weeks is equivalent to 6 sessions of hemodialysis.

Official Title
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Effect of Washing With Clove Extract on Inflammation and Infection Place Logging Shaldon Needle

Conditions
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Renal Failure

Intervention / Treatment
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* Other: clove extract
* Other: Betadine


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: age between 18-80 Exclusion Criteria: lack of cooperation patient to participate in the post test

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: inflammation<br>The effect of washing with betadine and clove extract on incidence of inflammation place logging shaldon catheter in the hemodialysis patients | Other: clove extract<br>* in intervention group, first will be washed the Catheter with Betadine after 2 minutes will be used of the clove extract with 2 ml of scrub for 15 seconds. The incidence of inflammation of vascular access will be assessed in patients on hemodialysis for each patient before starting the process over a period of 2 weeks is equivalent to 6 sessions of hemodialysis.<br>Other: Betadine<br>* in control group, will be washed the Catheter with Betadine<br>|
| Experimental: infection<br>The effect of washing with betadine and clove extract on incidence of infection place logging shaldon catheter in the hemodialysis patients | Other: clove extract<br>* in intervention group, first will be washed the Catheter with Betadine after 2 minutes will be used of the clove extract with 2 ml of scrub for 15 seconds. The incidence of inflammation of vascular access will be assessed in patients on hemodialysis for each patient before starting the process over a period of 2 weeks is equivalent to 6 sessions of hemodialysis.<br>Other: Betadine<br>* in control group, will be washed the Catheter with Betadine<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| inflammation severity questionnaire | effects of washing with clove extract on inflammation place logging shaldon needles in the hemodialysis patients that will be measured with inflammation severity questionnaire. | 6 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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inflammation, infection