Influence of Regular Exercise and Detraining on Metabolic and Emotional Parameters in Diabetic Individuals

Study Overview
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Brief Summary
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This quasi-experimental study aim to evaluate the effect of moderate aerobic exercise on glucose and lipid metabolism as well as the scales of anxiety and depression and levels of salivary cortisol in women with type 2 diabetes.

Detailed Description
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This quasi-experimental study aim to performed a 12-week training program (3 times/week, 60 minutes per session) which consisted of a supervised moderate aerobic exercise previously determined (50% to 70% of maximal Heart Rate) in women with type 2 diabetes.

Official Title
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Influence of Regular Exercise and Detraining on Metabolic and Emotional Parameters in Diabetic and Hypertensive Individuals

Conditions
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Diabetes Mellitus, Type 2

Intervention / Treatment
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* Other: Exercise


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: having normal physical examinations, no participation in regular, moderate or intensive exercise for at least 6 months before the study and not be following a diet Exclusion Criteria: the use of insulin and beta-blocker medications and the functional inability to perform exercise

Ages Eligible for Study
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Minimum Age: 40 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Moderate Exercise<br>Aerobic physical exercise was applied during 3 months, 3x/week on women with type 2 diabetic. The evaluation occurred before and after exercise in the same (and only) group, considering that this is a quasi-experimental study. | Other: Exercise<br>* This is a quasi-experimental study and the same group was evaluated before and after the exercise.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Glucose levels | After practicing the exercise for 3 months, patients were submitted to a new collection of blood for Glucose test. | 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Systolic and Diastolic blood pressure | Change in Systolic and Diastolic blood pressure were evaluated before and after physical exercise, during 3 months. | 3 months | 
| Heart Rate measurement | Change in heart rate was evaluated before, during and after physical exercise, during 3 months. | 3 months | 
| Glycated hemoglobin levels | After practicing the exercise for 3 months, patients were submitted to a new collection of blood for Glycated hemoglobin test. | 3 months | 
| Proteinuria levels | After practicing the exercise for 3 months, patients were submitted to a new collection of blood for proteinuria test. | 3 months | 
| Triglycerides levels | After practicing the exercise for 3 months, patients were submitted to a new collection of blood for triglycerides test. | 3 months | 
| High Density Level (HDL) Cholesterol levels | After practicing the exercise for 3 months, patients were submitted to a new collection of blood for High Density Level Cholesterol test. | 3 months | 
| Low Density Level (LDL) Cholesterol levels | After practicing the exercise for 3 months, patients were submitted to a new collection of blood for Low Density Level Cholesterol test. | 3 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Exercise, Exercise Therapy, Diabetes Mellitus, Type 2