The Effects of Different Dentin Hypersensitivity Treatment Methods on Quality of Life

Study Overview
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Brief Summary
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The aim of this study was to evaluate the effects of a self etch adhesive resin and two desensitizing agents(Calcium phosphate, 5% glutaraldehyde) in treatment of dentin hypersensitivity on the quality of life of individuals.

Detailed Description
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This in-vivo study was done among 69 participants who reported at least one sensitivite tooth(Schiff Sensitivity Score >1) as a result of the clinical examination. Participants were randomly divided into three treatment groups(n=23): I. Tetracalcium phosphate and dicalcium phosphate containing desensitizer (Teethmate Desensitizer) II. %35 hydroxyethyl methacrylate and %5 glutaraldehyde containing desensitizer (Gluma Desensitizer) III. Self-etch adhesive resin (Hybrid Bond) These materials used in treatment of dentin hypersensitivity in 6 months clinical follow-up and the effects on the quality of life of individuals were evaluated with Dentine Hypersensitivity Experience Questionnaire (DHEQ).

Official Title
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The Effects of Different Dentin Hypersensitivity Treatment Methods on Quality of Life

Conditions
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Dentin Hypersensitivity

Intervention / Treatment
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* Other: Teethmate Desensitizer
* Other: Gluma Desensitizer
* Other: Hybrid Bond


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Not having any systemic disease, 18 years and older, At least one tooth complaining of dentin hypersensitivity (Schiff score> 1), The acceptance of the volunteers participating in the research. Exclusion Criteria: Active periodontal disease, Periodontal surgery for the last 3 months, Use of desensitizing toothpaste or mouthwash in the last 3 months, Long-term use of analgesic and anti-inflammatory drugs, Having a history of allergies, Women during pregnancy or breastfeeding, Parafunctional habits (bruxism, teeth grinding etc.), The presence of caries, pulpitis or restoration in teeth, Tooth tissue loss due to erosion, abrasion and abfraction, Congenital anomalies, Cracked teeth were not included in the study.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Teethmate Desensitizer<br>Tetracalcium phosphate and dicalcium phosphate containing desensitizer | Other: Teethmate Desensitizer<br>* Powder and liquid contained in the material were mixed. It was applied to the buccal surface of the sensitive tooth. then it was washed away from the tooth surface. 1-4 sessions were applied until the sensitivity disappeared.<br>|
| Active Comparator: Gluma Desensitizer<br>%35 hydroxyethyl methacrylate and %5 glutaraldehyde containing desensitizer | Other: Gluma Desensitizer<br>* The material was applied to the buccal surface of the tooth with sensitivity. It was washed with water and removed from the tooth surface. 1-4 sessions were applied until the sensitivity disappeared.<br>|
| Active Comparator: Hybrid Bond<br>Self-etch adhesive resin | Other: Hybrid Bond<br>* It was applied to the buccal surface of the sensitive tooth with an applicator. It was cured with a LED light device. Dentin sensitivity was checked with evaporative air application. The process was repeated until the sensitivity disappeared.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Schiff Cold Air Sensitivity Scale Scores | Average scores based on Schiff cold air sensitivity scale after evaporative air application. The Schiff score ranges from 0 to 3. Minimum value is 0, maximum value is 3. An increase in the score from 0 to 3 indicates an increase in sensitivity. | Before treatment, immediately after treatment, 1 week, 1 month, 3 month and 6 month | 
| Visual Analog Scale(VAS) Scores | Average scores based on Visual Analog Scale(VAS) after applying evaporative air. The VAS score ranges from 0 to 10. The minimum value is 0 and the maximum value is 10. A score of 0 is defined as no pain while a score of 10 is defined as intolerable pain. | Before treatment, immediately after treatment, 1 week, 1 month, 3 month and 6 month | 
| Dentin Hypersensitivity Experience Questionnaire (DHEQ) scores | Data obtained after individuals complete the Dentin Hypersensitivity Experience Questionnaire. The decrease in the measured scores over time indicates that the quality of life has improved. | Change from baseline quality of life at 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Dentin Hypersensitivity, Desensitizing Agent, Adhesive Resin