Acromegaly: Patient And Physician Perspectives

Study Overview
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Brief Summary
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The purpose of the study is to assess the experiences of individuals with acromegaly who are receiving injections as part of their treatment regimen. Another objective of the study is to compare the patients' perception with their doctors' perceptions. The answers are important to help researchers and physicians understand what it is really like to take currently available treatments so that they can make efforts to improve patients' healthcare experiences, reduce treatment burden and, ultimately, improve patient's quality of life.

Official Title
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Acromegaly: Patient And Physician Perspectives

Conditions
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Acromegaly

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age >=18 years-old and <95 years-old Patient self-reported acromegaly diagnosis which will be further confirmed by a knowledge screening based on current medications and doses Currently on injectable Somatostatin analogues (SSA), Sandostatin® LAR or Somatuline® Depot, for >=12 months Have not had a change in dosage of their acromegaly treatment at the time of or since their last office visit Have seen their treating acromegaly physician within the past 12 +/-2 months NOTE: This timeframe allows two additional months for scheduling an appointment with their physician, since most patients should see their acromegaly physician at least once every 12 months Ability to read and understand English Live and receive acromegaly treatments in the US Willing to provide signed informed consent Exclusion Criteria: Previous or current participant in Mycapssa® (octreotide capsules) trial Use of Pegvisomant (Somavert®) monotherapy Use of Pasireotide (Signifor®)

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 94 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients<br>Patients diagnosed with acromegaly and currently taking long-acting somatostatin analogues for treatment. | |
| Physicians<br>Physicians for those treating the patients enrolled in the study. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Assess patient experiences with acromegaly treatments through patient questionnaires. | The primary objective of this study is to assess the experience of patients treated with SSA injections in the United States. Patients will be asked about previous and current acromegaly treatments they have taken from the time of diagnosis to the current day they are completing the survey. | The questionnaire should take no more than 60 minutes per subject. | 
| Assess patient satisfaction with acromegaly treatments. | The primary objective of this study is to assess the treatment satisfaction of patients treated with SSA injections in the United States. Patients will be asked about previous and current acromegaly treatments they have taken from the time of diagnosis to the current day they are completing the survey. | The questionnaire should take no more than 60 minutes per subject. | 
| Assess patients with acromegaly health-related quality of life. | The primary objective of this study is to assess the health-related quality of life for patients treated with SSA injections in the United States. Patients will be asked about their current quality of life and how acromegaly and acromegaly treatments may affect their quality of life from time of diagnosis to time of completing the survey. | The questionnaire should take no more than 60 minutes per subject. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Assess the concordance between patient's and physician's perceptions of acromegaly control (with/without biochemical lab results), | The second objective of this study is to compare patients' perception with those of their physicians in terms of aspects such as acromegaly control, treatment satisfaction, and health-related quality of life (HRQoL). | The questionnaire should take no more than 60 minutes per subject. | 
| Assess the concordance between patient's and physician's perceptions of acromegaly treatment satisfaction. | The second objective of this study is to compare patients' perception with those of their physicians in terms of aspects such as acromegaly treatment satisfaction. | The questionnaire should take no more than 60 minutes per subject. | 
| Assess the concordance between patient's and physician's perceptions of health-related quality of life. | The second objective of this study is to compare patients' perception with those of their physicians in terms of aspects such as health-related quality of life (HRQoL). | The questionnaire should take no more than 60 minutes per subject. |