WEakness and Atrophy: isoKinetic With Surface Electromyography Assessment in ACL Surgery

Study Overview
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Brief Summary
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An assessment of the effect of surgical anterior cruciate ligament (ACL) on thigh muscles is critical to the improvement of knee rehabilitation and preservation. However, if a large number of studies had rated surgical technics, giving high results level for ACL reconstruction (ACLR), muscle recovery is still conditioning functional success. Furthermore there is no consensus about criteria in return to sport. The aim of this exploratory study is to quantify the mechanisms of neuromuscular adaptation of muscle thigh after ACL surgery.

Detailed Description
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The aim of this study is to assess the qualitative and quantitative variations of the strength, work and fatigue of the thigh muscles after ACL surgery. The reference is the preoperative assessment (V1), the variation is measured on V2 (measurements at 3 months) and V3 (measures at 9 months). Each patient is his own control. In addition, a control group of healthy subjects is used to determine level of significance of each parameter.

Official Title
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Motor Unit Recruitment Study With Fatigue Testing: 9 Months Following up After Anterior Cruciate Ligament Surgery.

Conditions
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Anterior Cruciate Ligament Injury, Muscle Weakness

Intervention / Treatment
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* Other: isokinetic assessment


Participation Criteria
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Eligibility Criteria
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Inclusion criteria: ACLR group : men or woman 18 to 45 years old No injuries sequels on contralateral limb No contraindication to magnetic resonance imaging Control group : men or woman 18 to 45 years old No limb injuries sequels No contraindication to magnetic resonance imaging Exclusion criteria: age less than 18 years limb injuries sequels contraindication to magnetic resonance imaging

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Allocation: Non-Randomized
Intervention Model: Factorial Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: ACLR Group<br>experimental: ACL surgery Intervention: isokinetic assessment | Other: isokinetic assessment<br>* muscle torque assessement<br>|
| Other: Control group<br>other Intervention: isokinetic assessment | Other: isokinetic assessment<br>* muscle torque assessement<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| muscle torque | Newton.meter (N.m) | Change is being assessed between preoperative assessment (V1), measurement at 3 months (V2), measures at 9 months (V3) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| muscle work | Joule (J) | Change is being assessed between preoperative assessment (V1), measurement at 3 months (V2) and measures at 9 months (V3) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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MRI, knee muscle, strength, fatigue, ACL