linjc16/ctgov huggingface dataset:
Preoperative Anxiety in Pediatric Reconstructive Burn Patients: The Role of Virtual Reality Hypnosis

Study Overview
=================
Brief Summary
-----------------
Children with burns often require repeated reconstructive surgeries. These children tend to develop high levels of anxiety before coming to the operating room. Preoperative sedation, while somewhat effective in relieving this anxiety, has a number of side effects. The researchers hypothesized that preoperative anxiety could be effectively reduced by the utilization of a device which induces a relaxing hypnotic state through emmersion in a virtual reality environment.

Detailed Description
-----------------
The virtual reality environment is created by a Virtual Reality Hypnosis (VRH) device. The patient wears a headset which contains video and audio display. A twenty minute program is viewed, which guides the patient into a relaxed state via soothing audio and video input.

Official Title
-----------------
Preoperative Anxiety in Pediatric Reconstructive Burn Patients: The Role of Virtual Reality Hypnosis

Conditions
-----------------
Anxiety

Intervention / Treatment
-----------------
* Device: Virtual Reality Hypnosis
* Device: Placebo


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Child presenting for reconstructive burn surgery Exclusion Criteria: Visual or auditory difficulties

Ages Eligible for Study
-----------------
Minimum Age: 14 Years
Maximum Age: 21 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: v<br>Use of VRH headset | Device: Virtual Reality Hypnosis<br>* Use of virtual reality headset to induce hypnotic state<br>|
| Placebo Comparator: c<br> | Device: Placebo<br>* no use of device<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| anxiety reduction |  | preoperatively | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
preoperative anxiety, burn reconstruction
Kidney Biomarkers of Acute Kidney Injury in Patients With Knee Arthroplasty

Study Overview
=================
Brief Summary
-----------------
Sensitive renal markers have been studied abundantly in connection with open heart, liver and transplantation surgery; however in major orthopaedic surgery their use is anecdotal. The aim of the present study is to evaluate use of sensitive renal markers, NGAL (Neutrophil gelatinase associated lipocalin ), KIM-1 (Kidney injury molecule- 1), LFABP (liver-type fatty acid-binding protein), and IL-18 (interleukin -18), in patients coming for elective TKA (total knee arthroplasty) as a pilot study before large study concerning acute kidney injury in orthopaedic surgery.

Detailed Description
-----------------
Acute renal deterioration is a serious adverse event in elective surgery. Serum creatinine based diagnostics of acute kidney injury may delay diagnosis and produce false negative results since serum creatinine is affected by diet, muscle mass, used hydration therapy. In recent times new markers have been developed and tested in order to find sensitive, fast and reliable marker of renal deterioration.

Official Title
-----------------
Kidney Biomarkers of Acute Kidney Injury in Patients With Knee Arthroplasty- a Pilot Study

Conditions
-----------------
Arthroplasty, Replacement, Knee, Acute Kidney Injury

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: informed consent allergy to NSAIDs Exclusion Criteria: no informed consent

Ages Eligible for Study
-----------------
Minimum Age: 50 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients for elective TKA<br>patients with normal or near normal plasma creatinine who come for elective total knee arthroplasty | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Renal function | S-creatinine, Cystatin C, estimated GFR | time zero hours to 48 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Concentraton of sensitive renal markers | U-NGAL, P-NGAL, U-KIM-1, U-IL-18 | time zero hours to 24 hours | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
total knee arthroplasty, Kidney function, Renal markers
Fluoroscopically-guided Epidural Block in the Midthoracic Region: A Comparison of Anterioposterior Versus Oblique View Approach

Study Overview
=================
Brief Summary
-----------------
A comparison of anterioposterior versus oblique view approach method for fluoroscopically-guided epidural block in the midthoracic region. The investigators evaluate differences on total radiation time and technical feasibility between anterioposterior and oblique view approach method.

Conditions
-----------------
Low Back Pain Requiring Epidural Injection

Intervention / Treatment
-----------------
* Procedure: oblique view approach


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Adult patients who were scheduled for the transforaminal epidural injection in midthoracic region (T5-T7) Exclusion Criteria: Local anesthetic allergy, coagulopathy

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: AP group<br>oblique view approach during transforaminal epidural block | Procedure: oblique view approach<br> <br> |
| Active Comparator: OB group<br>oblique view approach during transforaminal epidural block | Procedure: oblique view approach<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Total radiation exposure time | Total radiation exposure time during whole epidural procedure. | immediately ≤1 sec after the confirmation of successful epidural injection | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The number of the needle readjustments | The number of the needle readjustments for successful epidural injection | immediately ≤1 sec after the confirmation of successful epidural injection |
Effect of Depressin Screening and Care Program at Community Health Center

Study Overview
=================
Brief Summary
-----------------
Depression affect between 5% and 10% of older adults seen in the primary care setting.Late-life depression is often chronic or recurrent and is associated with substantial suffering, functional impairment, and diminished health-related quality of life.Depressed, older primary care patients are frequent users of general medical services and may have poor adherence to medical treatments.They are also at increased risk of death from suicide and medical illnesses. The aim of this study is to examine whether depression screening and health care practitioner feedback are increased depression treatment rate. Depression screening is provided 60 or more who visited community health care center with a 15-item Geriatric Depression Scale.GDS scores of 10 or more were classified depression positive. Intervention group participants received twice remind calls from primary care nurse.

Conditions
-----------------
Elderly, Depression, Screening

Intervention / Treatment
-----------------
* Other: Reminding call


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 60 or more 10 or more in GDS scor Exclusion Criteria: severe cognitive problem

Ages Eligible for Study
-----------------
Minimum Age: 60 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Screening
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: intervention<br>remiding call | Other: Reminding call<br> <br> |
| No Intervention: Control<br>No intervention | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Reuptake rate |  | 12 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| reduced depressive symptoms | Geriatric Depression Scale Short Form (SGDS) | 12 weeks | 
| changed perceived heath status | Visual Analogue Scale (VAS) | 12 weeks |
Associated Pathologies Following Luxatio Erecta Humeri: A Retrospective Analysis of 31 Cases and Diagnostic Algorithm

Study Overview
=================
Brief Summary
-----------------
The aim of this study was to evaluate the clinical outcome of this rare injury with special emphasis on associated pathologies. Additionally, we aimed to develop an algorithm for the diagnosis of associated pathologies following LEH.

Conditions
-----------------
Shoulder Dislocation

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Included for analysis were all patients over 18 years of age who have been treated for LEH between at our department. Exclusion Criteria: Only injuries of the affected shoulder were taken into account, non-shoulder related pathologies were not addressed. Other types of shoulder dislocation except Luxatio erecta

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Luxation erecta<br>All patients with Inferior shoulder dislocation in fixed abduction, also known as luxatio erecta humeri (LEH) | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Functional clinical outcome | Functional outcome (Range of Motion of the shoulder) | at least 2months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| ASSOCIATED PATHOLOGIES | Number of participants with associated pathologies (for example fractures of the greater tuberosity, injuries of the rotator cuff or nerve palsy, e.g.) that were connected with this rare injury | at least 2 months | 
| Pain | Assessment for pain after operative/conservative therapy with the Visual Analog Score for pain | at least 2 months |
Antigenic and Antibody Detection of Candida

Study Overview
=================
Brief Summary
-----------------
In this study, a multicenter, prospective, synchronous blind, and controlled study was adopted to set the cut-off values of candida specific IgG, IgM, and Mn with the blood culture results as the gold standard, so as to evaluate the diagnostic value of candida specific IgG, IgM, and Mn levels in candida infection. the cut-off values of serum specific IgG, IgM and Mn of candida sinensis infected population in China were established by comparing the positive results of blood culture of 300 healthy people and 100 patients with positive candida sinensis blood culture as the gold standard and using ROC curve (ROC curve). 100 patients with positive tracheal aspiration culture and 100 patients with positive urine culture were enrolled. Serum levels of candida specific IgG, IgM and Mn were detected, and sensitivity, specificity, positive predictive value, negative predictive value and likelihood ratio of candida specific IgG, IgM and Mn in tracheal aspiration and urine were evaluated. 200 high risk patients with candida infection were enrolled, and the aseptic fluid culture and the simultaneous detection of serum specific IgG, IgM and Mn were adopted to explore the diagnostic value of the detection method. positive candida culture in sputum and positive candida culture in tracheal aspirate were taken as the control group to compare the levels of IgG, IgM and Mn in serum of the two groups, and to explore the diagnostic value of different sampling methods for candida pulmonary infection.

Official Title
-----------------
Department of Pulmonary & Critical Care Medicine, Chinese PLA General Hospital

Conditions
-----------------
To Evaluate the Diagnostic Value of Candida Antigen Antibody Detection for Candida Infection

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria:Age: (1) 18-85 years old; (2) Candida positive in aseptic humoral culture - Exclusion Criteria:(1) no informed consent has been signed; (2) patients with severe immune deficiency -

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Blood culture candida positive group<br> | |
| Tracheal aspiration candida culture positive group<br> | |
| Urine candida culture positive group<br> | |
| Other aseptic humoral candida positive group<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Serum specific IgG, IgM and Mn levels in the enrolled population | ELISA was used to detect the samples | 1-2 years |
START - Early Thrombocyte Administration to Patients With Ruptured Abdominal Aortic Aneurism

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to investigate the effect of platelet infusion prior to transfer to a vascular surgical department in patients with a ruptured abdominal aortic aneurism.

Official Title
-----------------
Thrombocyte Administration Versus no Thrombocytes to Patients With Ruptured Abdominal Aortic Aneurism Before Transport to Hospital With Vascular Surgical Department

Conditions
-----------------
Ruptured Abdominal Aortic Aneurism

Intervention / Treatment
-----------------
* Procedure: Platelet


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: diagnosed with rAAA either by clinical evaluation or CT or UL Exclusion Criteria: formerly randomized in the study aneurism not ruptured during operation
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: Control treatment<br>Usual transfusion regime to patients with rAAA | |
| Experimental: Thrombocyte<br>Early thrombocyte administration to patients with rAAA | Procedure: Platelet<br>* 2 portions of platelets (one portion = pooled from 4 donors, 350ml) infused when diagnosed with rAAA and vascular surgeon accepts to receive the patient, infused before transportation.<br>* Other names: Platelets;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mortality | Mortality during the first 30days after randomization, and time to death during the 30 days. | 30 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Acute myocardial infarction | Development of AMI during the first 30 days after randomization, and the time to development during the first 30 days. | 30 days | 
| Post operative kidney failure | The need for dialysis during the first 30 days, time to start of dialysis and length. | 30 days | 
| Post operative pulmonary insufficiency | Length of respirator treatment in the ICU during the first 30 days. | 30 days | 
| Length of stay in ICU | Length of stay in ICU | until discharged from ICU | 
| Length of stay in hospital | Until discharged from main surgical department or if transferred to local hospital, when the patient leave local hospital. | until discharged from hospital | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
rAAA, Platelets, TEG, Massive bleeding, Coagulopathy
EHR Embedded Comparative Effectiveness Studies--WWC

Study Overview
=================
Brief Summary
-----------------
Randomize Everyone is a research project to develop new informatics systems and statistical methods for supporting randomization processes in EHR systems to do comparative effectiveness research. Two demonstration projects are being conducted in the Dartmouth Hitchcock Medical Center, designed to evaluate different weight loss interventions and common practices in the treatment of chronic low back pain.

Detailed Description
-----------------
EHR Embedded Comparative Effectiveness Studies-WWC will be held in the Weight and Wellness Clinics at Dartmouth-Hitchcock Medical Center. This study consists of randomizing enrollees to either the dietitian/health coach appointment sequence or the health coach/dietitian appointment sequence.

Official Title
-----------------
Randomize Everyone: Creating Valid Instrumental Variables for Learning Health Care Systems

Conditions
-----------------
Obesity

Intervention / Treatment
-----------------
* Behavioral: Healthy Lifestyles Program
* Behavioral: Obesity Medicine Program


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Adults (>18) able to consent, with sufficient fluency in English; Able to be appropriately treated with either the Healthy Lifestyles Program or Obesity Medicine Program as determined by a WWC provider - Exclusion Criteria: Pregnant women; Prisoners; Children (<18) -

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Healthy Lifestyles Program<br>Usual care in the Healthy Lifestyles Program. | Behavioral: Healthy Lifestyles Program<br>* Regular group visits with a health coach in addition to routine dietician and clinician visits, reviewing successes and challenges from the previous session as well as data collected through self-monitoring<br>|
| Obesity Medicine Program<br>Usual care in the Obesity Medicine program. | Behavioral: Obesity Medicine Program<br>* A tailored approach to obesity care for patients including individual dietician and health coach visits as appropriate.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Factors for patient participation in EHR imbedded study | Patient Survey | Baseline | 
| Receipt of treatment | Patient Survey | 6 months post-enrollment | 
| Satisfaction with Treatment | Patient Survey | 6 months post-enrollment |
Effect of Fish Oil on Markers of the Metabolic Syndrome in Overweight Adolescent Boys

Study Overview
=================
Brief Summary
-----------------
The aim of the study is to investigate if dietary fish oil has a beneficial effect on blood pressure, insulin sensitivity, blood lipid profile, body composition and metabolic rate in healthy, but slightly overweight, teenage boys. We hypothesized that the n-3 long chain polyunsaturated fatty acids from fish oil might have greater effect during growth and development, as intervention trials studying the effect of fish oil on babies have shown greater effects than in adults.

Official Title
-----------------
Effect of n-3 LCPUFAs on Weight Reduction and Metabolic Syndrome.

Conditions
-----------------
Metabolic Syndrome

Intervention / Treatment
-----------------
* Dietary Supplement: Dietary oils (fish, vegetable oil)


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Weight above the 90th percentile for height and age. Exclusion Criteria: Smoking, severe illnesses.

Ages Eligible for Study
-----------------
Minimum Age: 13 Years
Maximum Age: 15 Years

Sexes Eligible for Study
-----------------
Male

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Fish oil<br>Daily dose = 6g fish oil baked into rye bread and wheat rolls. Participants were asked to consume two slices of rye bread and one wheat roll pr day. The fish oil was micro-incapsulated. | Dietary Supplement: Dietary oils (fish, vegetable oil)<br>* 6g pr day.<br>|
| Active Comparator: Vegetable oil (Mix of canola, palm and soy oil)<br>Daily dose = 6g vegetable oil baked into rye bread and wheat rolls. Participants were asked to consume two slices of rye bread and one wheat roll pr day. | Dietary Supplement: Dietary oils (fish, vegetable oil)<br>* 6g pr day.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Markers of the metabolic syndrome. Blood pressure, insulin sensitivity, HDL-cholesterol and triacylglycerol. |  | Intervention period = 16 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Body composition |  | 16 weeks | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Blood pressure, Insulin sensitivity, Blood lipid profile