Evolution of Corporeal Composition in the PeriOperative Period

Study Overview
=================
Brief Summary
-----------------
Denutrition and Obesity are risk factors for perioperative surgical complications. In patient with cancer, incidence of denutrition is markedly increased. Surgical resection of cancer induces a high intensity cellular stress response and catabolism reinforcing the risk for perioperative denutrition. In this study, we thought to investigate the change in body composition during the perioperative period using anthropometric measurements and Bioelectrical Impedance Analysis (BIA).

Detailed Description
-----------------
Body composition measurements will be performed before surgical procedure (7 days) and at day 1, day 5, 1 month, 3 months and 6 months after surgery. Others data will be recorded including anthropometric measurements, nutritional intake, occurence of surgical complication, type of surgical procedure, type and stage of cancer, and CT-scan measurements of subcutaneous abdominal fat, visceral fat and peri-renal fat before surgery and at 6 months.

Official Title
-----------------
Perioperative Body Composition Changes in Patients Undergoing Gastrointestinal or Lung Cancer Surgery

Conditions
-----------------
Gastrointestinal Cancer (Esophagus, Gastric, Pancreatic, Hepatic, Colorectal and Anal), Lung Cancer

Intervention / Treatment
-----------------
* Device: Bioelectrical Impedance Analysis


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Gastrointestinal cancer (esophagus, gastric, pancreatic, hepatic, colorectal and anal) Or Lung cancer And planned surgical resection Age > 18 years Exclusion Criteria: Surgical procedure planned < 48 h Pregnancy Presence of a cardiac stimulator

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Device: Bioelectrical Impedance Analysis|Measurements of body composition including fat mass, lean body mass, muscular mass, mineral mass, total body water, intra and extracellular water.|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| body composition | The primary objective is to study the change in body composition (fat mass, lean body mass, muscular mass, mineral mass, total body water, intra and extracellular water) during the perioperative period with respect to short, mid and long term outcome. | 1 month | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| perioperative complications | One of the secondary objective is to investigate the relationship between baseline body composition and the occurrence of surgical complications. | 6 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Gastrointestinal cancer, Lung cancer, Bioelectrical Impedance analysis, Body composition, Perioperative