Evaluation of the Effectiveness of Resistance Training in Patients With Psoriatic Arthritis

Study Overview
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Brief Summary
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The aim of this study was to assess the effectiveness of resistance training in improving functional capacity, muscle strength, quality of life and disease activity in patients with PSA.

Detailed Description
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The IG patients performed resistance exercises for the following muscles group: upper limbs, lower limbs and trunk. It was used a machine leg extension for the training on the lower limbs. For upper limbs we used a pulley triceps machine and front pull in addition to free weights (dumbbells). In order to perform the exercise program the study followed all the recommendations established by the American College of Sports Medicine (ACSM) (Ratamess et al., 2009). It was carried out two exercises for major muscle groups and one exercise for small muscles. The exercises were divided in 3 sets of 12 repetitions for each muscle group. The intensity of the exercises were 60% of one-maximum repetition (1RM). The exercise program involved pectoral exercises: crucifix and seat supine; biceps: alternated screw; triceps: triceps pulley; back: standing handsaw and pulled ahead; quadriceps: leg extensor and finally gluteo: standing hips extension. Control Group (CG) The control group was kept in a waiting list while continued with the standard pharmacological treatment during all the study. The patients were instructed to maintain their daily activities and to avoid any other non-pharmacological treatment. The exercise program was offered to the control group in the end of the study.

Official Title
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Resistance Training in Patients With Psoriatic Arthritis Improves Function, Disease Activity and Quality of Life

Conditions
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Psoriatic Arthritis

Intervention / Treatment
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* Other: Resistance exercise
* Other: Waiting list for the exercises


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Confirmed diagnosis of psoriatic arthritis, according to the CASPAR criteria Between 18 and 65 years of age, of both genders who agreed and signed the consent form. Patients should be-modifying drugs (DMARDs) on stable doses for at least three months and doses of non-steroidal anti-inflammatory drugs and corticosteroids stable for at least 4 weeks Exclusion Criteria: Patients were excluded: Uncontrolled cardiovascular disease Decompensated diabetes mellitus; diseases Severe psychiatric Fibromyalgia Other medical conditions that most disabling EA History of regular exercise (at least 30 minutes 2 times per week) during the last 6 months Arthroplasties of the hip and / or knee in the last 12 months; AND Any other medical condition that prevents the patient from performing resistance exercises

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Resistance exercise<br>Underwent resistance exercise twice a week, for twelve weeks for the following muscles group: upper limbs, lower limbs and trunk. It was carried out two exercises for major muscle groups and one exercise for small muscles. The exercises were divided in 3 sets of 12 repetitions for each muscle group. The intensity of the exercises were 60% of one-maximum repetition (1RM). The exercise program involved pectoral exercises: crucifix and seat supine; biceps: alternated screw; triceps: triceps pulley; back: standing handsaw and pulled ahead; quadriceps: leg extensor and finally gluteo: standing hips extension. | Other: Resistance exercise<br>* Underwent resistance exercise twice a week, for twelve weeks. The IG patients performed resistance exercises for the following muscles group: upper limbs, lower limbs and trunk. It was carried out two exercises for major muscle groups and one exercise for small muscles. The exercises were divided in 3 sets of 12 repetitions for each muscle group. The intensity of the exercises were 60% of one-maximum repetition (1RM). The exercise program involved pectoral exercises: crucifix and seat supine; biceps: alternated screw; triceps: triceps pulley; back: standing handsaw and pulled ahead; quadriceps: leg extensor and finally gluteo: standing hips extension.<br>|
| Other: Control group<br>Waiting list for the exercises. | Other: Waiting list for the exercises<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in the functional capacity | Evaluated by HAQ-S Health Assessment Questionnaire for the Spondylarthropathies | Baseline, after 45 and 90 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in the quality of life | Evaluated by the SF-36 questionnaire | Baseline, after 45 and 90 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Physical exercise, Psoriatic arthritis, Quality of life