Open Sinus Lift Technique With Simultaneous Implantation Using Platelet Rich Fibrin (PRF) Versus Nano-crystalline Hydroxyapatite

Study Overview
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Brief Summary
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Evaluation of bone quantity in open sinus lift technique with space maintaining using platelet rich fibrin (PRF) as sole augmentation material versus nano crystalline hydroxyapatite with simultaneous placing of implants.

Detailed Description
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Evaluation of bone quantity in open sinus lift technique with simultaneous implantation using platelet rich fibrin (PRF) versus Nano-crystalline Hydroxyapatite as sole grafting material in patients with atrophied posterior maxillary ridge which provides a new modality for treatment of patients with atrophied posterior maxillary ridge with least cost and a much easier way using platelet rich fibrin (PRF) as substitution to bone graft

Official Title
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Evaluation of Bone Quantity in Open Sinus Lift Technique With Simultaneous Implantation Using Platelet Rich Fibrin (PRF) Versus Nano-crystalline Hydroxyapatite as Sole Grafting Material in Patients With Atrophied Posterior Maxillary Ridge

Conditions
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Atrophied Posterior Maxillary Ridge

Intervention / Treatment
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* Procedure: Evaluation of bone quantity in open sinus lift technique with simultaneous implantation ( Nano crystalline hydroxyapatite)
* Procedure: Evaluation of bone quantity in open sinus lift technique with simultaneous implantation (PRF)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All patients should be seeking for implant supported prosthesis in posterior maxilla bilaterally All patients should have atrophied posterior maxillary ridge with the maximum height of the alveolar bone is from 3 mm to 5 mm Exclusion Criteria: Ongoing steroid therapy; Uncontrolled diabetes; Recent cardiovascular diseases; Inflammation of the maxillary sinus; Previous radiant therapy for neoplastic pathologies Patient who have had previous failed sinus augmentation, or exhibited pathological finding or had a history of maxillary sinus disease or operations or whose medical condition might increase surgical risk of the research protocol were excluded.

Ages Eligible for Study
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Minimum Age: 30 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Control group ( Hydroxyappetite)<br>Patients will undergo open sinus lift using nano crystalline hydroxyapatite as augmentation material and placing implants simultaneously then evaluation of bone quantity in open sinus lift technique with simultaneous implantation ( Nano crystalline hydroxyapatite) | Procedure: Evaluation of bone quantity in open sinus lift technique with simultaneous implantation ( Nano crystalline hydroxyapatite)<br>* • The sinus cavity will be augmented with bone graft ( Nano crystalline hydroxyapatite)<br>|
| Experimental: Test group (PRF)<br>Patients will undergo open sinus lift using PRF as sole augmentation material and placing implants simultaneously then Evaluation of bone quantity in open sinus lift technique with simultaneous implantation (PRF) | Procedure: Evaluation of bone quantity in open sinus lift technique with simultaneous implantation (PRF)<br>* platelet rich fibrin (PRF) as sole grafting material in created space (PRF)<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The amount of new bone formation the sinus cavity using CBCT | the amount of new bone formation of PRF in comparison with Nano-crystalline hydroxyappetite in millimeters using cone beam computed tomography (CBCT) | 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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simultaneous implantation, Dental implant, Open sinus Lifting, PRF, platelet rich fibrin (PRF)