Laser Puncture and Program of Lifestyle Modification in Lupus Females

Study Overview
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Brief Summary
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Serum lipid profile was significantly dysregulated in female systemic lupus erythematosus (SLE) patients

Detailed Description
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the research will recruit 64 female systemic lupus erythematosus (SLE) obese patients to divide them to two study groups equally. the study groups will receive, for 12 weeks, energy expenditure program (Pilates exercise, managed 5 times per week, combined with low calorie diet for).One group only will receive an additional laser puncture (with 3-time per-week design). The following points will be directly contacted by laser, for two minutes: GB34&28, ST25&36&40, SP6, and CV4&9&12.

Official Title
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Laser Puncture and Program of Lifestyle Modification in Lupus Females: Lipid Profile Response

Conditions
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Systemic Lupus Erythematosus

Intervention / Treatment
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* Behavioral: laser puncture, energy expenditure programming, and low-calories recommended diet programming
* Behavioral: energy expenditure programming and low-calories recommended diet programming


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: obese female participants Lupus females Exclusion Criteria: pregnant lupus female lactating lupus females neurologic or articular disorders another autoimmune conditions

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: group A<br>This 32-patient research group will receive, for 12 weeks, energy expenditure program (Pilates exercise, managed 5 times per week, combined with low calorie diet for).This research group will receive an additional laser puncture (with 3-time per-week design). The following points will be directly contacted by laser, for two minutes: GB34&28, ST25&36&40, SP6, and CV4&9&12. | Behavioral: laser puncture, energy expenditure programming, and low-calories recommended diet programming<br>* This research group will receive, for 12 weeks, energy expenditure program (Pilates exercise, managed 5 times per week) combined with low calorie diet .This research group will receive an additional laser puncture (with 3-time per-week design). The following points will be directly contacted by laser, for two minutes: GB34&28, ST25&36&40, SP6, and CV4&9&12.<br>|
| Active Comparator: Group B<br>This 32-patient research group will receive, for 12 weeks, energy expenditure program (Pilates exercise, managed 5 times per week, combined with low calorie diet ). | Behavioral: energy expenditure programming and low-calories recommended diet programming<br>* This research group will receive, for 12 weeks, energy expenditure program (Pilates exercise, managed 5 times per week) combined with low calorie diet.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| triglycerides | a lipid component will be measured in blood of females | 12 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| high density lipoprotein | a lipid component will be measured in blood of females | 12 weeks | 
| cholesterol | a lipid component will be measured in blood of females | 12 weeks | 
| low density lipoprotein | a lipid component will be measured in blood of females | 12 weeks |