The Efficacy of Robot-Assisted Intelligent Rehabilitation Treatment in Patients With AUD

Study Overview
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Brief Summary
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We aimed to test the efficacy of robot-assisted intelligent rehabilitation treatment in patients with alcohol use disorders with a randomized controlled trial. Specifically, the objective of this trial is to determine whether the robot-assisted intelligent rehabilitation treatment plus treatment as usual has greater efficacy than traditional therapy in the treatment of alcohol use disorders.

Detailed Description
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Based on artificial intelligence technology, face recognition technology, and virtual reality technology to develop an available Robot-assisted rehabilitation intelligent system. Then, using this intelligent system as a new way of Psychotherapy to provide treatment for patients with alcohol use disorders, and compare with traditional treatment to verify the efficacy and safety of the Robot-assisted rehabilitation intelligent system in Chinese patients with alcohol use disorders.

Official Title
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A Randomized Controlled Trial Protocol Testing the Efficacy of Robot-Assisted Intelligent Rehabilitation Treatment in Patients With Alcohol Use Disorders

Conditions
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Alcohol Use Disorder

Intervention / Treatment
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* Device: robot-assisted rehabilitation intelligent treatment
* Other: treatment as usual


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Between the ages of 18-55; Meeting DSM-5 criteria for alcohol use disorders; Withdrawing alcohol for less than 12 months; Ability to use computers; Signing informed consent; Exclusion Criteria: Having comorbidities of other neuropsychiatric diseases; Diseases that affect cognitive function, such as a history of head trauma, cerebrovascular disease, epilepsy, etc. With a family history of mental illness Not familiar with computer operation, unable to complete assessment and treatment.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 55 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: robot-assisted rehabilitation intelligent treatment<br>Both groups will receive treatment as usual(TAU) provided by the clinical team, including medication, exercise, and psychotherapy. Robot-assisted intelligent rehabilitation treatment will be delivered to participants in the testing group through an addiction prevention and relapse intervention intelligent system. | Device: robot-assisted rehabilitation intelligent treatment<br>* Participants assigned to this condition were offered 10 individual sessions of robot-assisted rehabilitation treatment, delivered by the Robot-assisted rehabilitation intelligent system. The system contains 10 core cognitive-behavioral therapy (CBT) skill topics (such as functional analysis, coping skills training, reviewing practice exercises, and explaining CBT concepts). A robot therapist demonstrates the target CBT skills and assigns homework to participants. The treatment framework is semi-structured through human-computer interaction. The forms of interaction include inquiries, statements, recommendations summaries, and knowledge assessments.<br>Other: treatment as usual<br>* Both groups will receive treatment as usual, including medication, exercise, and psychological education.<br>|
| Other: treatment as usual<br>Participants in the treatment-as-usual group were offered standard treatment at the mental health hospitals, which consisted of group and/or individual therapy, as determined by the clinical team. | Other: treatment as usual<br>* Both groups will receive treatment as usual, including medication, exercise, and psychological education.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Desire for alcohol | The primary outcome is patients' desire for alcohol,measured by Visual Analogue Scale(VAS). | 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change Readiness and Treatment Eagerness | The secondary outcome includes participants' Change Readiness and Treatment Eagerness, measured by the Stages of Change Readiness and Treatment Eagerness Scale(SOCRATES). | 3 months | 
| Impulsiveness | The secondary outcome includes participants' level of impulsiveness, measured by the Barratt Impulsiveness Scale(Barratt). | 3 months | 
| Anxiety | The secondary outcome includes the participants' level of anxiety, measured by generalized Anxiety Disorder-7(GAD-7). | 3 months | 
| Depression | The secondary outcome includes the participants' level of depression, measured by Patient Health Questionnaire-9(PHQ-9). | 3 months | 
| Perception of stress | The secondary outcome includes participants' perception of stress, measured by the Perceived Stress Scale(PSS). | 3 months | 
| Sleep Quality | The secondary outcome includes participants' sleep quality, measured by Pittsburgh Sleep Quality Index(PSQI). | 3 months | 
| coping style | The secondary outcome includes participants' coping style, measured by Simplified Coping Style Questionnaire(SCSQ). | 3 months | 
| use of alcohol | The secondary outcome includes participants' use of alcohol. | 3 months |