The Minnesota Manual Dexterity Test As A Measure Of Hand Function in Multiple Sclerosis

Study Overview
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Brief Summary
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The aim of the study is to report the results of manual dexterity using the Minnesota Manual Dexterity Test in people with Multiple Sclerosis.

Detailed Description
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Upper limb can be affected even in early stage in people with Multiple Sclerosis (pwMS). Manual dexterity is important to maintain upper limb function and 9-Hole Peg Test (9HPT) is used as gold standard to assess dexterity in pwMS. There are no studies evaluating manual dexterity with the Minnesota Manual Dexterity Test (MMDT) in pwMS. This study aims to: reporting the results of manual dexterity using the Minnesota Manual Dexterity Test and comparing the test results with healthy volunteers, examining the relationship between MMDT and 9HPT, ABILHAND, grip strength, pinch strength, fatigue.

Official Title
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Upper Limb Assessment in Multiple Sclerosis: The Minnesota Manual Dexterity Test As A Measure Of Hand Function

Conditions
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Multiple Sclerosis

Intervention / Treatment
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* Other: Test Group
* Other: Control Grup


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: (1) age 18-65; (2) definitive diagnosis of MS according to McDonald criteria; (3) ability to read and write in Turkish. Exclusion Criteria: (1) acute attacks of MS (within 3 months); (2) cognitive impairment (Mini Mental test result 24 points and below); (3) having spasticity (3 and above according to Modified Ashworth Scale) (4) any chronic disease other than MS; (5) being addicted to alcohol or drugs,

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Test Group<br>people with multiple sclerosis | Other: Test Group<br>* Individuals who meet the inclusion criteria will be evaluated for manual dexterity, performance, muscle strength and fatigue, respectively, on a predetermined day.<br>|
| Control Group<br>healthy volunteers | Other: Control Grup<br>* Individuals who meet the inclusion criteria will be evaluated for manual dexterity, performance, muscle strength and fatigue, respectively, on a predetermined day.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Minnesota Manual Dexterity Test | to assess manual dexterity, higher scores mean a worse outcome. | baseline (on the predetermined assessment day) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 9-Hole Peg Test | to assess manual dexterity. higher scores mean a worse outcome. | baseline (on the predetermined assessment day) | 
| ABILHAND | to assess for performance of activity. score range 0-46 point, higher scores mean a better outcome. | baseline (on the predetermined assessment day) | 
| grip strength | using hand dynamometer. higher scores mean a better outcome. | baseline (on the predetermined assessment day) | 
| pinch strength | using pinchmeter. higher scores mean a better outcome. | baseline (on the predetermined assessment day) | 
| Fatigue Severity Scale | to assess fatigue. score range 0-7 point, higher scores mean a worse outcome. | baseline (on the predetermined assessment day) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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multiple sclerosis, upper limb, manual dexterity, assessment, minnesota manual dexterity test