School-based Physical Activity Intervention for Obesity Among Adolescents With Intellectual Disability in Hong Kong

Study Overview
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Brief Summary
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Considering that children with intellectual disability (ID) might be more vulnerable to obesity than their counterparts in the general population. This study aimed to develop and evaluate the effectiveness of an adapted physical activity (APA) program in reducing weight among adolescents with ID. The hypothesis of the study was the APA program would be able to decrease obesity among adolescents with ID.

Detailed Description
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Background: Children with intellectual disability (ID) might be more vulnerable to obesity than their counterparts in the general population. This study aimed to evaluate the effectiveness of an adapted physical activity (APA) program in reducing weight among adolescents with ID. Methods: A 9-month randomized controlled trial of a school-based APA program was conducted in adolescents with ID and overweight/obesity in Hong Kong. The intervention group received the APA program which consisted of endurance and strength-building exercises at a frequency of two sessions per week, while the control group received routine PE classes as usual. Data on obesity-related variables were collected before the intervention, at the midpoint of the intervention and after the intervention. Linear mixed-effect models were used to examine the intervention effects.

Official Title
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School-based Physical Activity Intervention for Obesity Among Adolescents With Intellectual Disability in Hong Kong

Conditions
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Obesity

Intervention / Treatment
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* Other: Adapted physical activity


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: aged between 12 and 18 years overweight and obesity mild or moderate intellectual disability Exclusion Criteria: physical disability medical predispositions towards obesity (genetic syndrome or drug treatment) contraindications (e.g. asthma, heart disease) having participated in other exercise programs in the past 6 months.

Ages Eligible for Study
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Minimum Age: 12 Years
Maximum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: intervention group<br>Participants in the intervention group participated in the APA intervention consisting of simple and fun endurance and strength-building exercise at a frequency of two sessions per week. | Other: Adapted physical activity<br>* This PA program was modified from an adapted physical activity (APA) program that designed for obesity management among adolescents with intellectual disability (ID). The aim of the APA program was to promote PA and health for people in special needs. In this study, the APA program was carefully designed based on a comprehensive pre-intervention assessment of each adolescent with ID, so that can be able to address their individual needs in learning and adaption. The APA program comprised three stages of APA training at school and each stage consisted of simple and fun endurance and strength-building exercise, at a frequency of two sessions per week, and lasting for about three months.<br>|
| No Intervention: control group<br>Participants in the control group received no intervention in the study time period. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| BMI Change | The primary outcome variable was change in BMI (weight (kg) / height2 (m)) that was further calculated from the height and weight measured at school in the morning time. Height was measured to the nearest 0.1 cm using a stadiometer and weight was measured to the nearest 0.1 kg on a TANITA digital scale (TBF-410) with the subject wearing lightweight clothing and no shoes. | Change from baseline at 4 months and 9 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| BMIz Change | The BMIz was converted from the BMI values using WHO 2007 reference standards. A z-score of 0 is equal to the mean and is considered normal. Lower numbers indicate values lower than the mean and higher numbers indicate values higher than the mean. Higher values denote a higher BMI. | Change from baseline at 4 months and 9 months | 
| Weight Change | Weight was measured to the nearest 0.1 kg on a calibrated TANITA digital scale (TBF-410) with the subject wearing lightweight clothing and no shoes. | Change from baseline at 4 months and 9 months | 
| Percent Body Fat Change | Percent body fat was measured with the TANITA digital scale (TBF-410) using foot-to-foot bioelectrical impedance analysis. | Change from baseline at 4 months and 9 months | 
| Waist Circumference Change | Waist circumference (cm) was measured with a flexible meter ribbon accurate to 0.1 cm at the midway between the lowest rib margin and the top of the iliac crest at the end of gentle expiration | Change from baseline at 4 months and 9 months | 
| Waist-to-height Ratio Change | Waist-to-height ratio was calculated by dividing the waist circumference by the height. | Change from baseline at 4 months and 9 months | 
| Cardiorespiratory Fitness Change | Cardiorespiratory fitness was assessed using the 9-minute run/walk test. The test measured how far a person can cover a flat surface 25 meters in length over a 9-minute period. | Change from baseline at 4 months and 9 months | 
| Muscular Strength and Endurance Change | The muscular strength and endurance were measured by handgrip strength and sit-ups. The handgrip strength was measured using a dynamometer (Takei, TKK5001, GRIP-A digital dynamometer). The sit-ups measured the total number of correctly completed sit-ups performed in 30 seconds. | Change from baseline at 4 months and 9 months | 
| Flexibility Change | Flexibility was measured by the sit-and-reach test. | Change from baseline at 4 months and 9 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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adolescents, intellectual disability, overweight, obesity, physical activity, intervention