Effects of Oral Ingestion of Drinking Water Using a Tumbler That Emits Far Infrared Rays on Metabolic Profile

Study Overview
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Brief Summary
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The investigators conduct a randomized, double-blind, placebo-controlled study to investigate the effects of oral ingestion of drinking water using a tumbler that emits far infrared rays at room temperature on metabolic profile in adults for 8 weeks.

Detailed Description
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The investigators conduct a randomized, double-blind, placebo-controlled study to investigate the effects of oral ingestion of drinking water using a tumbler that emits far infrared rays at room temperature on metabolic profile in adults for 8 weeks; the safety of the compound are also evaluate. The Investigators examine lipid profile, glucose, liver and renal function at baseline, as well as after 4, 8 weeks of intervention. Thirty adults were administered either 1.8 L of drinking water using a tumbler that emits far infrared rays at room temperature or drinking water using a sham-tumbler each day for 12 weeks.

Official Title
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Effects of Oral Ingestion of Drinking Water Using a Tumbler That Emits Far Infrared Rays at Room Temperature on Metabolic Profile in Adults: a RCT

Conditions
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Metabolic Problems

Intervention / Treatment
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* Dietary Supplement: infrared water group
* Dietary Supplement: sham group


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 19 years and older Exclusion Criteria: aspartate aminotransferase (AST) or alanine aminotransferase (ALT) more than twice the highest reference value serum creatinine ≥ 1.5 mg/dL) uncontrolled diabetes mellitus (a fasting glucose of >160 mg/dL) uncontrolled hypertension (BP > 160/100 mmHg) severe gastrointestinal symptoms alcohol abuser pregnant or lactating women allergic to the ingredient involved cardiocebrovascular diseases or any cancer during the six months prior to study smoker

Ages Eligible for Study
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Minimum Age: 19 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Infrared water group<br>This group takes drinking water using a tumbler that emits far infrared rays at room temperature for 8 weeks. | Dietary Supplement: infrared water group<br>* This group takes 1,8 L of drinking water using a tumbler that emits far infrared rays at room temperature.<br>|
| Sham Comparator: sham group<br>This group takes drinking water using a tumbler at room temperature for 8 weeks. | Dietary Supplement: sham group<br>* This group takes 1,8 L of drinking water using a tumbler at room temperature.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Low density lipoprotein cholesterol (LDL-C) | Change of LDL-C during 8 weeks | Change from baseline level of LDL-C at 8 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| aspartate transaminase (AST) | Change of AST during 8 weeks | Change from baseline level of AST at 8 weeks | 
| creatinine | Change of creatinine during 8 weeks | Change from baseline level of creatinine at 8 weeks | 
| homeostasis model assessment of insulin resistance (HOMA-IR) | Change of HOMA-IR during 8 weeks | Change from baseline level of HOMA-IR at 8 weeks | 
| body weight | Change of body weight during 8 weeks | Change from baseline level at 8 weeks | 
| free fatty acid | Change of free fatty acid during 8 weeks | Change from baseline level at 8 weeks | 
| alanine transaminase (ALT) | Change of ALT during 8 weeks | Change from baseline level of ALT at 8 weeks |