Upper Limb Ergometer on Pulmonary Function Among Patients With Spinal Cord Injury.

Study Overview
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Brief Summary
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Randomized Control Trial, To determine the effects of arm ergometer exercise on pulmonary function of Spinal Cord Injury.

Detailed Description
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The spinal cord is a tubular structure contained nervous tissue. This acts as a transmission channel of nerve signals within the brain and spinal cord. It contains grey and white matter. The grey matter consists of cell bodies of different sensory and motor neurons and white matter consists of oriented spinal tracts. By 2007, a prospective observational study had been conducted after a disaster occurred in Pakistan which was the most cataclysmic natural disaster in country's history as a result 73000 people were lost their lives and 126000 were harmed. There was no Spinal Cord Injury (SCI) registry existed in the country but according to different estimates 650-750 had been effected of SCI. In United States SCI incidence mainly due to higher percentage of violence-related SCIs (18%)which is higher compared to the western Europe (8%) Australia (2%). In Pakistan the most common traumatic cause of SCI was falling from different cause followed by road traffic accident (RAT) (25.2%) and functional aerobic impairment (FAI) (8.4%). The way that SCI is associated with fantastic expenses and human sufferings , yet careful statistics of SCI are not accessible in dominant of developing countries including Pakistan. Total lung capacities become abnormal in chronic spinal cord injury patients. Changes in chest wall compliance and decreased respiratory muscle strength leads to abnormal changes in overall lung capacities.

Official Title
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Effects of Upper Limb Ergometer on Pulmonary Function Among Patients With Spinal Cord Injury.

Conditions
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Spinal Cord Injuries

Intervention / Treatment
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* Other: Conventional Treatment
* Other: Upper Limb ergometer training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: SCI at level of upper and lower thoracic spine Exclusion Criteria: Cardiovascular diseases Active inflammation or infection going in body Malignancies Those Individuals with have psychiatric disorders Any other neurological condition related to brain (stroke, parkinson's etc) Pressure ulcers (grade 3 and grade 4)

Ages Eligible for Study
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Minimum Age: 25 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Conventional Treatment<br>Conventional Treatment: Deep breathing, Assisted coughing, Sustained stretching, Splinting, Bracing and Functional mobility | Other: Conventional Treatment<br>* Conventional Treatment: Deep breathing: 10-15 reps, twice a day (BD) Assisted coughing 10-15 reps, BD range of motion (ROM)+ stretching 10 reps, BD Tilt table standing<br>|
| Experimental: Upper Limb ergometer training<br>Conventional Treatment + Upper Limb (UL) ergo-meter exercise | Other: Upper Limb ergometer training<br>* Conventional Treatment + upper limb (UL) ergometry exercise UL ergometry exercise 15 to 20 mints , 2 times ,five days per week for 6 weeks.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Forced vital Capacity (FVC) | Changes from the Baseline, the digital spirometer is used in clinical setting to analyze Forced vital Capacity in Liters | 6 Week | 
| Forced Expiratory Volume in 1 second (FEV1) | Changes from the Baseline, the digital spirometer is used in clinical setting to analyze Forced Expiratory Volume in 1 second FEV1 in Liters | 6 Week | 
| Peak Expiratory Flow (PEF) | Changes from the Baseline, the digital spirometer is used in clinical setting to analyze peak expiratory flow PEF in Liter/second. | 6 Week | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Pulmonary Function, Spinal Cord Injury, Spirometry, Ergometer