Clinical Practice Guideline for Neonatal Extravasation Injury

Study Overview
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Brief Summary
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This study is aimed to evaluate the effectiveness of an evidence-based clinical practice guideline in the prevention and management of neonatal extravasation injury, and to examine the change in nurses' knowledge of and adherence to the guideline.

Detailed Description
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A study with controlled before-and-after design was conducted. The clinical practice guideline was developed and a multifaceted educational program was delivered for nurses. Neonatal outcomes were collected at baseline and after completion of the intervention. The changes in nurses' level of knowledge and adherence to the guideline were also measured.

Official Title
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Clinical Practice Guideline on the Prevention and Management of Neonatal Extravasation Injury

Conditions
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Extravasation Injury

Intervention / Treatment
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* Other: Clinical practice guideline for prevention and management of extravasation injury


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Neonates who were admitted for intravenous medication or infusion therapy, and Neonates whose parents were equal to or over 18 years old and able to communicate in Chinese or English. Exclusion Criteria: Neonates who were born with congenital dermatological problems such as ichthyosis and epidermolysis bullosa.

Ages Eligible for Study
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Maximum Age: 1 Year

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Sequential Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Clinical practice guideline (CPG) group<br>Implementation of an evidence-based clinical practice guideline and delivery of an educational programme | Other: Clinical practice guideline for prevention and management of extravasation injury<br>* Implementation of an evidence-based clinical practice guideline and delivery of an educational programme for nurses<br>|
| No Intervention: Usual care group<br>Usual care | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in rate of peripheral intravenous extravasation | The number of the incidents divided by the total number of catheter days and multiplied by 1,000 | Change from Baseline rate at one month | 
| Change in rate of extravasation from a central line | The number of the incidents divided by the total number of catheter days and multiplied by 1,000 | Change from Baseline rate at one month | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in nurses' level of knowledge | The Neonatal Extravasation Knowledge Test | Change from Baseline Knowledge level at six months | 
| Change in nurses' adherence to clinical practice guidelines | A 27-item audit tool | Change from Baseline Adherence level at six months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Intravenous nursing, Newborn infant, Neonatal intensive care units, Evidence-based professional practice