linjc16/ctgov huggingface dataset:
Level of Lacrimal Passage Obstruction

Study Overview
=================
Brief Summary
-----------------
Detect anatomical level of acquired lacrimal passage obstructions among patients with epiphora. They were evaluated and divided into four groups Punctal, Canalicular, Nasolacrimal duct and Mixed groups according to level of obstruction

Detailed Description
-----------------
In a 3 years period adult patients with obstructive epiphora were evaluated clinically by Probing /irrigation of lacrimal passages to detect anatomical level of obstruction. The main site of obstruction was the common canaliculus where 2/3 of patients had canalicular problems. The second common site of obstruction is nasolacrimal duct followed by the puncti.

Official Title
-----------------
Symptomatic Acquired Lacrimal Passage Obstruction: Clinical Evaluation of the Level of Obstruction in Adult Patients of Upper Egypt

Conditions
-----------------
Lacrimal Apparatus Diseases

Intervention / Treatment
-----------------
* Diagnostic Test: Probing /irrigation of lacrimal passages


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Watering of the eye Acquired lacrimal obstructions Adult patients with Exclusion Criteria: No previous lacrimal surgery Congenital lacrimal obstructions

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Epiphora<br>Adult patients suffering from watering of the eye included in the study to detect level of obstruction | Diagnostic Test: Probing /irrigation of lacrimal passages<br>* Probing of the lacrimal passage was done using #00 Bowman's lacrimal probe which can reveal any narrowing (resistance) or obstruction (soft stop) of the canaliculi during its advancement from punctum towards the lacrimal sac.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Level of obstruction of lacrimal system | The level was detected either Punctal, Canalicular, Nasolacrimal duct or Mixed | 3 years |
Occupational Balance, Fear and Agoraphobia

Study Overview
=================
Brief Summary
-----------------
This study was planned to investigate occupational balance, fear of Covid-19 and agoraphobia in adults during the Covid-19 pandemic.

Detailed Description
-----------------
During the Covid-19 pandemic, the occupational balance of individuals change and the sedentary activities preferences, that pose a risk for health, increase.The outbreak also produced effects such as fear of sickness and death in addition to changing daily life and work routines, occupational balance and social participation. This study was planned to investigate occupational balance, fear of Covid-19 and agoraphobia in adults during the Covid-19 pandemic.

Official Title
-----------------
Evaluation of Occupational Balance, Fear and Agoraphobia in Adults

Conditions
-----------------
Covid19

Intervention / Treatment
-----------------
* Other: this study is not an intervention study


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: between 19-65 years of age Exclusion Criteria: <19 years and >65 years old

Ages Eligible for Study
-----------------
Minimum Age: 19 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: this study is not an intervention study|this study is not an intervention study|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Occupational Balance Questionnaire | The Occupational Balance Questionnaire (OBQ) is a scale that measures self-rated OB in different dimensions. 11 item in the scale is scored on a 4-point scale from 'strongly disagree' to 'strongly agree'. The total score is obtained by summing the individual items and ranges from 0 to 33, with higher scores indicating higher OB. | 3 months |
Persistent Pain to Impair Daily Activities Following Thoracic Surgery

Study Overview
=================
Brief Summary
-----------------
Can pain impairment of daily activities be shown to be procedure specific, and thus used as an alternative to pain scoring.

Official Title
-----------------
Persistent Pain to Impair Daily Activities Following Thoracic Surgery

Conditions
-----------------
Pain

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age < 18 years old Elective lung cancer surgery (VATS) Exclusion Criteria: Non-Danish residence

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Thoracic surgery<br>Lung cancer patients | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain impairment | We measure persistent pain impairment in patient > 12 months folowing surgery | >12 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
daily activities
The Association Between Different Monocyte Subsets and Coronary Collateral Development

Study Overview
=================
Brief Summary
-----------------
Collateral growth and coronary angiogenesis are chronic adaptations to myocardial ischemia. Collateralization helps to restore blood flow and as a result salvages myocardium in severely ischemic myocardial regions. Thus, good collateral development in patients with severe coronary artery disease (CAD) improves ventricular function and prognosis (1-3). However, coronary collateral development is different among patients even with similar degrees of coronary artery stenosis. Several factors, such as diabetes mellitus (4) and duration of myocardial ischemic symptoms (5) have been reported to effect coronary collateral development. At the cellular level, inflammatory cells, especially monocytes have an important role in collateralization. In a series of experimental studies with animals, it has been shown that monocytes are important elements for development of collateral vessels (6-7). In a recent study, it has been demonstrated that increased circulating monocyte count is related to good collateral development in patients with stable coronary artery disease (8). Monocytes in human blood are heterogeneous and can be classified into two subsets according to the presence or absence of the FcγRIII receptor CD16 (9): CD14++CD16- monocytes characterized by high level expression of the CD14 cell surface receptor but no expression of CD16 receptor, and CD14+CD16+ monocytes characterized by the co-expression of CD16 receptor with either high or low level expression of the CD14 receptor. These subsets differ in function and response to several cytokines. Our aim in this study was to find out any possible relationship between the levels of circulating monocyte subsets and coronary collateral development.

Conditions
-----------------
Coronary Artery Disease, Coronary Ischemia

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: > 95% stenosis of at least one major coronary artery in their first coronary angiogram Exclusion Criteria: previous percutaneous or surgical revascularization history evidence of ongoing infection and inflammation known malignancy and chronic kidney disease (serum creatinine > 1.5 mg/dl diabetic patients

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Good-poor collateral<br>Patients who had good and poor collaterals formed 2 groups | |
| Good collateral, Poor collateral<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Coronary collateral development, monocyte subsets, collateralization
A Survey on the Under-treatment of hypercholeSterolemia (EPHESUS Trial)

Study Overview
=================
Brief Summary
-----------------
In this study, within the secondary prevention group patients ( diabetes mellitus, coronary artery disease, peripheral artery disease, who have had events atherosclerotic cerebrovascular ) , statin use requirement , patients compliance and reaching target LDL-cholesterol levels (according to European guidelines ) will be evaluated.

Detailed Description
-----------------
In the majority of patients treated with lipid lowering agents are not under control in accordance with the lipids manual. In this study, within the secondary prevention group patients ( diabetes mellitus, coronary artery disease, peripheral artery disease, who have had events atherosclerotic cerebrovascular ) , statin use requirement , patients compliance and reaching target LDL-cholesterol levels (according to European guidelines ) will be evaluated. The investigators' aim is to determine the role of education and knowledge in reaching target LDL cholesterol levels in these patients. İn addition , the investigators want to emphasize in high-risk patients who are receiving or not receiving cholesterol-lowering treatment what is their target values , (LDL < 100 mg / dL and high -risk patients with LDL < 70 mg / dL in very high-risk patients ) and to determine what is the rate of patients and to the importance of reaching their target cholesterol levels. İn addition ,to evaluate the patients habits of the using statin dose .After screening , physician treatment decisions and reasons will be documented.

Official Title
-----------------
Evaluation of Perceptions, Knowledge and Compliance With tHE Guidelines for Secondary Prevention in Real Life Practice: A Survey on the Under-treatment of hypercholeSterolemia (EPHESUS Trial)

Conditions
-----------------
Hyperlipidemias

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with coronary artery disease (acute coronary syndromes, post- myocardial infarction patients, who have a history of percutaneous coronary intervention , history of coronary artery by-pass graft ) Patients with carotid artery lesions or peripheral artery disease , Type 2 diabetes mellitus patients Exclusion Criteria: acute coronary syndrome in last 1 month pregnancy or the first 6 months postpartum ICU patients or emergency patients...etc.(other than polyclinic)

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The number of patients with secondary prevention group receiving appropriate lipid lowering therapy |  | 2 months |
Pre-hospital Tourniquet in Extremity Injury

Study Overview
=================
Brief Summary
-----------------
2.1. Objective: • Primary Objective: To compare outcomes of patients with extremity injuries presenting with or without pre-hospital tourniquet placement. 2.2. Study Outcome Measures Primary Outcome: Incidence of arrival in shock (SBP <90) Secondary Outcomes: Demographics, comorbidities, mechanism of injury, cause of injury, diagnosis codes, procedure codes, Injury Severity Scale, Abbreviated Injury Scale, operative management vs. non-operative management, radiologic findings, pathologic findings, tourniquet effectiveness (as determined both subjectively by trauma surgeon and objectively by presence vs. absence of pulse below level of tourniquet application), total number of units of blood products transfused within first 24 hrs, total number of units of blood products for index admission, type of blood products or other fluid given, hospital length of stay, ICU length of stay, ventilator days, infectious complications, other complications, discharge disposition, 24 hr mortality, overall mortality.

Detailed Description
-----------------
This is a prospective, observational study. All patients who present to the participating ED's who meet inclusion/exclusion criteria will be identified by the treating trauma surgeons. Data collected will include basic patient demographics, data regarding the patient's injuries, data regarding tourniquet use, and data regarding outcomes. Please see the attached data collection tool for specifics (Appendix 12.1). Data will be collected prospectively in an observational manner using the data collection tool. Data collected on individual collection sheets will be de-identified. We plan to complete the data collection and analysis by 01\01\2021.

Official Title
-----------------
Prospective Observational Multi-center Analysis of Pre-hospital Tourniquet in Extremity Injury

Conditions
-----------------
Extremity Injury

Intervention / Treatment
-----------------
* Other: pre-hospital tourniquet placement


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: ≥ 18 y/o Patients with extremity injuries With a tourniquet in place OR Who the treating physician deems could have benefited from tourniquet placement Exclusion Criteria: Children Prisoners Pregnant women Patients with non-traumatic bleeding requiring tourniquet use

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: pre-hospital tourniquet placement|patients with extremity injuries presenting with or without pre-hospital tourniquet placement.|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of arrival in shock | (Systolic Blood Pressure <90 mmHg (Millimeter of mercury)) | First 24 hours . |
Molecular Assessment of Lymph Nodes in Patients With Resected (Stage I to IIIA) Non-small Cell Lung Cancer

Study Overview
=================
Brief Summary
-----------------
This is a prospective study of surgically resected samples and lymph nodes of lung cancer patients. For histopathologically positive lymph nodes from a complete resection, the investigators would like to analyse tumor tissue by allelotyping and comparing these results with those observed in the primary lung tumor to establish a cartography of molecular alteration in resected lung cancer. For non histopathologically positive lymph nodes, the investigators would like to research the presence (or not) of micrometastasis by allele-specific PCR (polymerase chain reaction).

Detailed Description
-----------------
Genetic: It is a prospective study during two years with three years for follow-up. No control group is recruited.

Official Title
-----------------
Research of Molecular Markers for Diagnosis and/or Prognosis in Lymph Node Metastasis of Resected Non-small Cell Lung Cancer

Conditions
-----------------
Lung Cancer

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with resectable non-small cell lung cancer (stage I to IIIA), with a complete resection of the tumor and paired lymph nodes. Informed consent is required. Exclusion Criteria: Another cancer Chemotherapy before surgical treatment
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Lung cancer patients, non-small cell lung cancer, molecular marker, lymph node completed resected, Lung cancer samples and paired lymph node resected
Biomagnetic Characterization of Gastric Dysrhythmias:Study 2

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to use the Squid magnetometer (Superconducting QUantum Interference Device) to help diagnose electrical and mechanical abnormalities of the stomach and intestines.

Detailed Description
-----------------
The Squid magnetometer is a non-invasive investigational device that measures the electrical activity in the smooth muscle of the intestines. Volunteers with normal bowel activity, those with gastric problems, and diabetics with gastric problems will be studied under the SQuid to determine normal and abnormal activity. Diabetics with an abnormal gastric emptying study will be asked to participate.

Official Title
-----------------
Biomagnetic Characterization of Gastric Dysrhythmias:Study 2

Conditions
-----------------
Ischemia

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Normal volunteers, those with stomach problems, and Diabetics with abnormal gastric emptying study Exclusion Criteria: Diabetics with a normal gastric emptying study Participants with claustrophobia

Ages Eligible for Study
-----------------
Minimum Age: 14 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| poor blood flow<br>Group with partial ischemia to the small intestine | |
| Good blood flow<br>Group with normal blood flow, given different conditions to effect electrical currents in normal smooth muscle | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| to observe a difference in the magnetic activity between the normal and diseased smooth muscle of the stomach and intestines. |  | 2010 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| to specifically study the electrical activity of diabetics with an abnormal gastric emptying. |  | 2010 | 
| Measurement of mesenteric ischemia |  | 2010 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Blood supply, Mesentery
Transoral Removal of Specimen During Laparoscopic Gastric Resection

Study Overview
=================
Brief Summary
-----------------
Investigators aimed to present the patients who underwent laparoscopic gastrectomy with transoral specimen extraction.

Detailed Description
-----------------
Minimally invasive surgical procedures such as NOSE (Natural orifice spesmen extraction) and NOTES (Natural orifice translumenal endoscopic surgery) are gradually increasing. The transoral way is probably the least used for NOSE.

Official Title
-----------------
Transoral Removal of Specimen During Laparoscopic Gastric Resection

Conditions
-----------------
Gastric Disease, Bariatric Surgery Candidate

Intervention / Treatment
-----------------
* Procedure: transoral specimen extraction


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: laparoscopic gastric resection Patients aged 18-70 years Exclusion Criteria: other transorally removed organs (appendix, gallbladder, surrenal)

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: transoral specimen extraction|transoral specimen extraction during laparoscopic gastric resection|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Transoral Specimen Extraction During Laparoscopic Gastric Resection | laparoscopic gastric resections due to sleeve gastrectomy or pyloric obstruction will be observed after transoral removal. | 2 years |
Genetic Determinants of the Response to Salbutamol Among Asthma Patients

Study Overview
=================
Brief Summary
-----------------
The response to salbutamol varies greatly among individuals. Data from previous studies indicate that some of the variability is accounted for by genetic polymorphisms in the gene encoding for the adrenoceptor subtype β2. The current study was designed to evaluate variability in the response to salbutamol among recently diagnosed patients who have not been treated by β2 agonists or corticosteroids. Lung function tests will be performed prior to and following a single dose administration of salbutamol through inhalation. Additional pharmacodynamic indices will be monitored including pulse and blood pressure. Three samples of plasma will be drawn for the evaluation of salbutamol plasma concentration.

Official Title
-----------------
Evaluation of Genetic Factors That May Account for Variability in the Response to Salbutamol Among Patients Suffering From Asthma

Conditions
-----------------
Asthma

Intervention / Treatment
-----------------
* Drug: Albuterol


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 18 years and older Recently diagnosed as asthmatic Exclusion Criteria: Current treatment by β2 agonist Current treatment by corticosteroids Acute asthma attack

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: Albuterol|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in lung function tests after salbutamol inhalation |  |  | 
| Change in blood pressure and pulse after salbutamol inhalation |  |  | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Albuterol, β2 Adrenergic receptor, Polymorphism