A Prospective Registry For Patients With Non-Tuberculous Mycobacterial (NTM) Pulmonary Disease in Korea.

Study Overview
=================
Brief Summary
-----------------
The incidence and prevalence of pulmonary disease due to Non-tuberculous mycobacteria (NTM) is increasing worldwide, and this trend has been confirmed in Korea. Treatment of NTM pulmonary disease is difficult and usually requires more than two years of long-term treatment, and the antibiotic regimens used in treatment vary. Therefore, it is difficult to track the natural history of patients with NTM pulmonary disease, to evaluate the treatment outcome, and to understand the effect of specific medicines on the outcome. Establishing a prospective registry of patients with NTM pulmonary disease is expected to accurately evaluate the progress, treatment modality, and treatment outcome of NTM pulmonary disease.

Official Title
-----------------
A Prospective Registry For Patients With Non-Tuberculous Mycobacterial (NTM) Pulmonary Disease in Korea.

Conditions
-----------------
Pulmonary Disease, Pulmonary Infection, Non-Tuberculous Mycobacterial Pneumonia

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Clinical diagnosis of NTM pulmonary disease. The causative agent of NTM pulmonary disease includes: M. avium complex, or M. abscessus subspecies abscessus, or M. abscessus subspecies massiliense, or M. kansasii. Patients who starts new treatment (those who have previous history of treatment are eligible) Exclusion Criteria Patients who have been treated for more than 4 weeks. The causative agent of NTM pulmonary disease is none of M. avium complex, M. abscessus subspecies abscessus, M. abscessus subspecies massiliense, or M. kansasii.

Ages Eligible for Study
-----------------
Minimum Age: 20 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Treatment success rate | Analysis of treatment success rate according to species of NTM lung disease patients in Korea | Through study completion, at 1 year after treatment start at enrollment | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Comparison of the efficacy among different regimens for the treatment of certain species of NTM | Comparison of the outcomes measured by culture conversion among different regimens for the treatment of certain species of NTM | Through study completion, at 1 year after treatment start at enrollment | 
| Number of participants with changing culture results during treatment | Number of participants with changing culture results during treatment | Through study completion, at 1 year after treatment start at enrollment | 
| Number of participants with treatment-related adverse events | Number of participants with treatment-related adverse events specifically described in the protocol | Through study completion, at 1 year after treatment start at enrollment | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
NTM, Registry, Pulmonary infection