Medical Evaluation of Scanner in Coronary Syndrome

Study Overview
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Brief Summary
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Many recent publications have reported encouraging results on diagnostic cardiac multislice CT performance in 1) coronary artery disease, 2) coronary arterial bypass graft potency and 3) intrastent restenosis. These single center studies were made on a limited number of patients (range, 50-130) and focused mainly on one of the indications mentioned above. Moreover, results were often given after exclusion of low quality examinations. At last, no study has compared the diagnostic performance of the different CT systems '16, 40 and 64) in these populations.

Detailed Description
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These single center studies were made on a limited number of patients (range, 50-130) and focused mainly on one of the indications mentioned above. Moreover, results were often given after exclusion of low quality examinations. At last, no study has compared the diagnostic performance of the different CT systems '16, 40 and 64) in these populations.

Official Title
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Medical and Economic Medical Evaluation of Scan Multislice of Coronary Artery in Exploration of Stable Coronary Syndrome. Comparison With Quantitative Coronarography

Conditions
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Coronary Syndrome

Intervention / Treatment
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* Procedure: multislice coronary scan


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients' ≥18 years, of both sexes Coronary angiography in patients with suspected of known CAD, instable clinical conditions. Clinical status allowing performance of coronary angiography 48 à 72h after CT examination Informed consent signed by patient Exclusion Criteria: Patients in whom clinical status does not allow delayed coronary angiography Irregular heart rate, in particular atrial fibrillation Renal insufficiency (serum creatinine >150 µmol/l Radiology examination with use of iodin agent with 48h before) CT coronary K now intolerance to iodin agents Patients unable to hold breathing < 20 seconds Pregnancy

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 1<br>Scan | Procedure: multislice coronary scan<br>* multislice coronary scan<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Specificity and sensibility of scanner |  | visit 1 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Quality of coronary scanner imaging |  | visit 1 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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stenosis, coronaropathy, stent, bypass surgery, suspect, known