Text Message Quit Vaping Intervention for Young Adults

Study Overview
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Brief Summary
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This research study, conducted by Truth Initiative, will help us learn how text messaging can help young adults between 18 and 24 years of age quit vaping.

Detailed Description
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The Quit Vaping Study (QVS)'s primary aim is to conduct a fully powered comparative effectiveness trial to evaluate the effectiveness of a quit vaping text message program in promoting abstinence from e-cigarettes among young users aged 18-24. This study is a 2-arm randomized controlled trial conducted among young users aged 18-24 recruited through online channels. Participants will be randomized to a quit vaping text message intervention or to an assessment-only control condition and followed for 7 months to roughly correspond to 6-months post-treatment. The secondary aim is to examine potential mediators of program effectiveness, including treatment engagement and changes in self-efficacy and perceived social support for quitting.

Official Title
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A Randomized Trial of a Text Message Quit Vaping Intervention for Young Adults

Conditions
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Tobacco Cessation

Intervention / Treatment
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* Other: This is Quitting
* Other: Assessment only Control


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 18-24 Past 30-day use of e-cigarettes containing nicotine Interest in quitting e-cigarette use in the next 30 days US residence Exclusion Criteria: Failure to confirm mobile number after initial sign-up

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 24 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Arm 1: Intervention - Text message intervention Arm 2: Control - Assessment only
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: This is Quitting<br>Participants will be enrolled to receive messages from This is Quitting. Users receive one age-appropriate message per day tailored to their enrollment date or quit date, which can be set and reset via text message. Those not ready to quit receive 4 weeks of messages focused on building skills and confidence. Users who set a quit date receive messages for a week preceding it and 8 weeks afterward that include encouragement and support, skill- and self-efficacy building exercises, coping strategies, and information about the risks of vaping, benefits of quitting, and cutting down to quit. Keywords COPE, STRESS, SLIP, and MORE provide on-demand support. | Other: This is Quitting<br>* Text message-based intervention for quit vaping support.<br>|
| Other: Assessment only Control<br>After an initial enrollment message, participants will be contacted periodically to assess e-cigarette use. At the end of the intervention period, they will receive information on how to sign up for This is Quitting if they are interested in the program | Other: Assessment only Control<br>* Assessment only<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of Participants With Self-reported 30-day Point Prevalence Abstinence (ITT) | Number of participant who responded No to the question In the past 30 days, did you vape at all, even a puff of someone else's? Denominator is all randomized participants. | 7 months post enrollment | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of Participants With Self-reported 30-day Point Prevalence Abstinence (Responder Only) | Number of participants with who responded 'No to the question In the past 30 days, did you vape at all, even a puff of someone else's? Denominator is participants with responses only. | 7 month post enrollment | 
| Number of Participants With Self-reported 7-day Point Prevalence Abstinence (ITT) | Number of participants who responded No to the question Have you used any vape, even one puff, in the past 7 days? Denominator is all randomized participants. | 7 months post enrollment | 
| Number of Participants With Self-reported 7-day Point Prevalence Abstinence (Responder Only) | Number of participants who responded No to the question Have you used any vape, even one puff, in the past 7 days? Denominator is those who responded to the question only. | 7 months post enrollment | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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E-cigarette Cessation, Vaping Cessation, Mobile Intervention, Digital Intervention