Periodontal Impact of Eating Disorders (the PERIOED Study)

Study Overview
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Brief Summary
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This study evaluated the periodontal status of patients suffering from eating disorders (anorexia nervosa and bulimia nervosa). The work hypothesis is that eating disorder patients have a higher risk for periodontal diseases than non-eating disorder subjects.

Detailed Description
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Eating disorders have been associated with poor oral health. However, the relationship between eating disorders and periodontal diseases is less-established. Participants will be periodontally assessed using a full-mouth clinical evaluation.

Official Title
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Periodontal Impact of Eating Disorders (the PERIOED Study)

Conditions
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Periodontal Diseases, Eating Disorder, Anorexia Nervosa, Bulimia Nervosa

Intervention / Treatment
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* Other: diagnostic


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: In and out eating disorder patients Subject with a diagnosis of anorexia nervosa or bulimia nervosa for at least 5 years Subject affiliated to the French social insurance Exclusion Criteria: Subject who do not speak French Subject who is not able to read and/or understand the information form Subject who take anti-inflammatory medications or antibiotics at dental examination Subject who has received any dental treatment that could interfere with the periodontal status 3 month before the clinical examination (scaling and root planning, orthodontic treatment ongoing) Subject who has less than 10 teeth

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Anorexia Nervosa<br>interview and periodontal full-mouth examination | Other: diagnostic<br>* full-mouth periodontal examination<br>|
| Bulimia Nervosa<br>interview and periodontal full-mouth examination | Other: diagnostic<br>* full-mouth periodontal examination<br>|
| Control<br>interview and periodontal full-mouth examination | Other: diagnostic<br>* full-mouth periodontal examination<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Clinical Attachment Loss (CAL) | Periodontal probing depth and gingival recession are measured in millimeters using a manual periodontal probe (HuFriedy PCP UNC 15 probe, Chicago, IL, USA). At the clinical examination day, CAL is calculated as periodontal probing depth (mm) + gingival recession (mm) at 6 sites per tooth. | at examination day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| gingival inflammation | Gingival inflammation is measured by bleeding on probing score (%) at 6 sites per tooth. | at examination day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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periodontitis