Evolution of Pulmonary Ultrasound in Patients Hospitalized for Covid (Coronavirus Disease) 19

Study Overview
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Brief Summary
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Clinical thoracic ultrasound plays an important role in the exploration, diagnosis and follow-up of thoracic pathologies. The COVID (Coronavirus Disease) epidemic is leading to a large influx of patients in the emergency department with respiratory disorders. The rapid diagnosis of respiratory disorders in infected patients is important for further management. Chest ultrasound has already demonstrated its value in the diagnosis of pneumonia in the emergency department with superiority over chest X-ray. However, there is little data on the thoracic ultrasound semiology of viral pneumonia in general and of COVID in particular.

Detailed Description
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Chest ultrasound has already shown its value in the diagnosis of pneumonia in the emergency department with superiority over chest X-ray. However, there is little data on the thoracic ultrasound semiology of viral pneumonia in general and of COVID in particular. Peng reported data from 20 patients and compared them to chest CT. The abnormalities are a thickening of the pleuropneumonia line, an interstitial syndrome with B lines, corresponding to frosted glass opacities, confluent B lines (snowstorm appearance) corresponding to interstitial infiltrate, sub-pleural alveolar opacities corresponding to sub-pleural condensations, more frank alveolar images corresponding to alveolar opacities. A multifocal aspect was associated with involvement of more than 2 lobes. However, the frequency of these abnormalities as well as the sensitivity of the echo are not detailed in this article. Another Italian article describes a clinical case of COVID-19 pneumonia with sub-pleural involvement and irregularity of the pleuro-pulmonary line. Clinical thoracic ultrasound has a major potential interest during the COVID epidemic: available at the patient's bedside, avoiding the need to move around, feasible for the physician during his visit, easy to clean especially if ultraportable devices are used, fast and not exposing the staff any more than the usual clinical examination. In order to determine whether this technique is useful in the management of infected patients or patients suspected of COVID-19 infection with respiratory signs, we propose a descriptive prospective study evaluating the ultrasound semiology of COVID-19 pneumonia and the interest of ultrasound in the evolutionary follow-up of these patients.

Official Title
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Prospective Descriptive Study on the Evolution of Pulmonary Ultrasound in Patients Hospitalized for Covid19

Conditions
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Pneumonia, Viral, COVID-19

Intervention / Treatment
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* Other: No special intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients admitted to hospital with proven COVID-19 infection with respiratory signs warranting a chest CT scan Exclusion Criteria: Patient not agreeing to have his or her data collected for the study Unconscious patient

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 105 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patient hospitalised with COVID-19 infection<br>Patients admitted to hospital with proven COVID-19 infection with respiratory signs warranting a chest CT scan | Other: No special intervention<br>* No special intervention : Ultrasound data will be collected<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Characteristics of pulmonary ultrasound for Covid-19 patients | description of ultrasound abnormalities for Covid-19 patients | Day one | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Characteristics of pulmonary ultrasound for Covid-19 patients | description of ultrasound abnormalities for Covid-19 patients | Day 3 | 
| Characteristics of pulmonary ultrasound for Covid-19 patients | description of ultrasound abnormalities for Covid-19 patients | Day 14 | 
| Charateristics of pulmonary CT-scan for Covid-19 patients | description of CT-scan abnormalities for Covid-19 patients | Day 1 | 
| Charateristics of pulmonary CT-scan for Covid-19 patients | description of CT-scan abnormalities for Covid-19 patients | Day 3 | 
| Charateristics of pulmonary CT-scan for Covid-19 patients | description of CT-scan abnormalities for Covid-19 patients | Day 14 |