Visual Outcome of Vitrectomy After Refractive Surgery

Study Overview
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Brief Summary
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Results of retinal detachment surgery may be affected in cases with history of previous intraocular surgery.

Detailed Description
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Pars-plana vitrectomy for management of retinal detachment has favorable visual outcome with early intervention and development of small gauge instruments, cases with previous refractive surgery may be affected by other factors that may change the final visual outcome. In this study, we aim to analyze the effect of refractive surgeries on the final visual outcome after vitrectomy for the management of retinal detachment.

Official Title
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Visual Outcome of Small Gauge Pars-plana Vitrectomy for Retinal Detachment With Previous Refractive Surgery

Conditions
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Retinal Detachment, Refractive Errors

Intervention / Treatment
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* Procedure: Vitrectomy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: cases diagnosed with primary retinal detachment and prepared for pars-plana vitrectomy. cases with previous history for refractive surgery were enrolled in refractive surgery group. Exclusion Criteria: cases with corneal diseases or trauma that may affect the final visual outcome. cases with other retinal diseases that may affect the final visual outcome as age related macular degenerations and diabetic eye disease.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Vitrectomy group with previous refractive surgery<br>Cases with primary retinal detachment that are prepared for pars-plana vitrectomy with previous history of refractive surgery. | Procedure: Vitrectomy<br>* Small gauge pars-plana vitrectomy for management of retinal detachment.<br>* Other names: Pars-plana vitrectomy;|
| Active Comparator: Vitrectomy group with no previous intraocular surgery<br>Subjects with primary retinal detachment that are prepared for pars-plana vitrectomy with no previous history of intraocular surgery. | Procedure: Vitrectomy<br>* Small gauge pars-plana vitrectomy for management of retinal detachment.<br>* Other names: Pars-plana vitrectomy;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual acuity | Changes in visual acuity from baseline and at the 6th month of follow-up measured by snellen chart and converted to logMAR units for statistical analysis. | Baseline and 6 months after surgery. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Corneal endothelial cells count | Changes in corneal endothelial cells counts measured by specular microscopy in cells/millimeters2 units. | Baseline and 6 months after surgery. |