Joint Thoracic Oncology Research Unit of LYon: Lung cancerS DatabaSE (ULYSSE)

Study Overview
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Brief Summary
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Prospective longitudinal cohort associated to blood collection, pathological samples collection, and radiological and pathological imaging collection.

Official Title
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Prospective Longitudinal Cohort Associated to Blood Collection, Pathological Samples Collection, and Radiological and Pathological Imaging Collection

Conditions
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Lung Cancer

Intervention / Treatment
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* Other: Quality of life questionnaire
* Biological: Blood sample
* Other: Quality of life questionnaire
* Other: Quality of life questionnaire
* Other: Quality of life questionnaire


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patient treated for a thoracic cancer in the Lyon University Hospital: non-small cell lung cancer, small cell lung cancer, mesothelioma… Diagnosis can be done: By cytology or pathologic assessment Or by multidisciplinary team meeting decision: Irradiation without morpho-metabolic sampling Treatment without sampling based on non-invasive molecular data Exclusion Criteria: - Refusal to participate For optional blood sampling : < 30 kg for blood collection No blood sampling schedule for care

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Intervention Model: Single Group Assignment
Interventional Model Description: One questionnaire between diagnostic annoucement and first line treatement One 6 months later One before second line treatment One 6 months later after second line treatment Optionnal Veinous Blood Sample (28 mL) between the diagnostic annoucement and the first line of treatment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Cohort of Adults with lung cancer<br>Patients newly diagnosed with lung cancer. | Other: Quality of life questionnaire<br>* One questionnaire between diagnostic annoucement and first line treatement<br>Biological: Blood sample<br>* One optional veinous blood sampling (24 ML) between the first diagnostic annoucement and before the first treatment for lung cancer<br>Other: Quality of life questionnaire<br>* One questionnaire 6 months later after first line treatment<br>Other: Quality of life questionnaire<br>* One questionnaire before second line treatment<br>Other: Quality of life questionnaire<br>* One questionnaire 6 months later after second line treatment<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of participants registered in the lung cancer database | cohort open to recruitment during 10 years with 10 years of patients follow-up | 20 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Data collection, lung cancer