Frequency of Fibromyalgia in Behcet Disease

Study Overview
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Brief Summary
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In various studies, the incidence of fibromyalgia in Behçet's patients is widely distributed. It was aimed to investigate the frequency and severity of fibromyalgia in Behcet disease in province Bursa.

Detailed Description
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There are few studies in the literature investigating the frequency of fibromyalgia in Behçet's disease. In various studies, the incidence of fibromyalgia in Behçet's disease was 5.7% -37.1%, which is widely distributed. There are no studies in literature comparing disease severity and pain thresholds at trigger points in fibromyalgia with and without Behcet's disease. In this study, it was aimed to investigate the frequency of fibromyalgia in Behcet's disease according to the criteria defined by the American Colloge of Rheuatology in 2010 and updated in 2013. It was also aimed to compare the severity of disease in fibromyalgia with and without Behcet's disease.

Official Title
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Frequency of Fibromyalgia in Behcet Disease in Province Bursa

Conditions
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Fibromyalgia, Behcet Syndrome

Intervention / Treatment
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* Diagnostic Test: group 1:Patients diagnosed with Behcet disease
* Diagnostic Test: group 2: Patient diagnosed with fibromyalgia without Behcet disease


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients diagnosed with Behcet disease according to international study group criteria Patients diagnosed with fibromyalgia according to classification criteria that were defined by the American Collage of Rheumatology in 2010 and updated in 2013 Patients older than 18 Patients younger than 75 Exclusion Criteria: Participants which were previously diagnosed with diabetes mellitus Participants which were previously diagnosed with chronic renal failure Pregnant women

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| 1<br>group Behcet | Diagnostic Test: group 1:Patients diagnosed with Behcet disease<br>* Frequency and severity of fibromyalgia will be investigated in patient diagnosed with Behcet disease<br>|
| 2<br>group fibromyalgia | Diagnostic Test: group 2: Patient diagnosed with fibromyalgia without Behcet disease<br>* Severity of fibromyalgia will be investigated in patient diagnosed with fibromyalgia<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| fibromyalgia 2013 criteria | Fibromyalgia 2013 criteria were derived from the 10-item symptom score from the Symptom Impact Questionnaire (SIQR) symptoms and the 28-area pain location inventory (PLI). If the patients PLI score is above 17 (range 0-28) and an SIQR symptom score is above 21 (range 0-50), the participant will be diagnosed with fibromyalgia | Six months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Fibromyalgia impact questionnaire | The fibromyalgia impact questionnaire (FIQ) has 21 individual questions . All questions are based on an 11-point numeric rating scale of 0 to 10, with 10 being 'worst'. In the FIQ, all questions are framed in the context of the past 7 days. The total maximal score of the FIQ is 100. | Six days | 
| Pain thresholds | Pain thresholds will be recorded by applying pressure to the 28 sensitive points until the participants demonstrate pain. Manual algometry device will be used to measure the pain threshold. | Six months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Fibromyalgia, Behcet Disease, Trigger points