The Diagnostic Value of Acupoint Sensitization Based on Stable Angina Pectoris

Study Overview
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Brief Summary
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Investigators adopt cross-sectional study design to carry out the exemplary research in the aspects of disease diagnosis.This study is designed to confirm the hypothesis acupoint sensitization is associated with a severity of angina pectoris, which may contribute to the diagnosis of stable angina pectoris. After the eligible participants recruited in group, the coronary artery lesions will be evaluated through coronary angiography and the Canadian Cardiovascular Society(CCS) angina pectoris classification will also be evaluated at the same time. The degree of acupoint sensitization will be tested by the electronic Von Frey instrument by one professional acupuncturist with total 12 acupoints, including Shenmen,Yinxi, Shaohao,Jiquan,Neiguan, Ximen, Quze, Shanzhong, Juque, Jueyinyu, Xinyu, Duyu. Analysis were conducted to explore relationships between the degree of acupoint sensitization, the degree of coronary artery stenosis and CCS angina pectoris classification. Diagnostic value will be further analyzed in the final step.

Official Title
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The Diagnostic Value of Acupoint Sensitization Based on Stable Angina Pectoris

Conditions
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Stable Angina Pectoris, Acupoint Sensitization, Correlation Analysis, Diagnostic Value

Intervention / Treatment
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* Combination Product: Coronary angiography,Canadian Cardiovascular Society angina pectoris classification for the severity of angina and electronic Von Frey instrument for testing the degree of acupoint sensitization


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients meet the diagnostic criteria of ACC/AHA angina pectoris of coronary heart disease The frequency of angina attacks were greater or equal to twice a week over the previous 3 months Patients agree to do coronary angiography examination and sign the informed consent. Exclusion Criteria: People with mental disabilities and intelligent obstacle Patients who can't accomplish the detection of acupoint sensitization Patients with allergic condition, especially the contrast media Patients with acute myocardial infarction, unstable angina, during arrhythmia and serious diseases which can affect the blood supply of myocardial Patients with skin or peripheral nerve paresthesia, pain or the detect area of skin ulcerate Pregnant or lactating women Patients who undergoing other clinical trials

Ages Eligible for Study
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Minimum Age: 35 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Combination Product: Coronary angiography,Canadian Cardiovascular Society angina pectoris classification for the severity of angina and electronic Von Frey instrument for testing the degree of acupoint sensitization|All the interventions were tested for only once|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The degree of acupoint sensitization | The value will be obtained through the electronic Von Frey instrument | About 1 hour | 
| The degree of coronary artery stenosis | Data will be obtained through coronary angiography | About 2 hours | 
| Canadian Cardiovascular Society angina pectoris classification |  | About 1 hours | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Stable Angina Pectoris, Acupoint sensitization, Correlation analysis, Diagnostic value