Characteristics and Outcomes of Odontoid Fragility Fractures in Elderly

Study Overview
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Brief Summary
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Usually, cervical spine fractures are not considered as osteoporotic fractures. However, recent studies show that odontoid fractures are the most common fractures of the cervical spine in elderly and may occur in a context of low trauma energy. Thus, the goal of this observationnal study is : to describe the different type of odontoid fracture and to characterize bone status in elderly patient (>65 y) who underwent odontoid fracture in a context of low trauma energy. To describe short and long term outcomes

Detailed Description
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All patients over 65 y admitted for low trauma odontoid fracture will be consecutively included in the study after informed consent. The investigators will record: clinical risk factor of osteoporosis and health habits including accomodation type of fracture and characterization of the odontoid fracture on imaging (standard X ray / MRI / QCT) Bone status : bone mineral density on DXA, lab tests for secondary osteoporosis check-up, previous vertebral fracture on VFA or X ray osteoporosis managment : nutrition, vitamin D, anti-osteoporotic drugs treatment of the fracture : surgical / non surgical adverse event during hospitalization lenght of hospital stay type of discharge Follow-up à 3 and 12 months : dead vs alive ; accomodation ; autonomy ; new fracture

Official Title
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Characteristics and Outcomes of Odontoid Fragility Fractures in Elderly

Conditions
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Odontoid Fracture, Osteoporosis, Surgery

Intervention / Treatment
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* Other: observational


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: all patients over 65 y admitted for low traumat odontoid fracture Exclusion Criteria: patient < 65 y traumatic odontoid fracture

Ages Eligible for Study
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Minimum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: observational|describe bone status and outcome of odontoid fracture|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| bone status at the time of odontoid fracture: bone mineral density, prevalent osteoporotic fracture, vitamin D status | clinical risk factor of osteoporosis, prevalent clinical osteoporotic fracture, bone mineral density measured by DXA, vertebral fracture assessment to detect other vertebral fracture, serum concentration in 25OHvitamin D | from date of inclusion until to 3 weeks after the event. Inclusion will be proposed within 2 weeks after the fracture | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| mortality | mortality after odontoid fracture during hospitalization and at 3 and 12 monts | during hospitalization - 3 and 12 months after inclusion | 
| morbidity | incident osteoporotic fracture, adverse event such as infection, cardiovascular event, neurological event | during hospitalization - 3 and 12 months after inclusion | 
| loss of autonomy | lenght of hospital stay, type of discharge (home, nursing home, rehabilitation bed care, institutionalized accomodation | discharge, 3 and 12 months |