The Influence of the Nutritional Status of Women Between 30 and 45 Years of Age on the Condition of the Skin and Body Composition

Study Overview
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Brief Summary
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Goal is to investigate the differences in skin condition and body composition among women with different dietary habits aged 30-45 years. Study will be focused onto sub-groups of female subjects following omnivorous, vegetarian or vegan diet.

Detailed Description
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Investigators will investigate differences among female subjects aged 30-45 years following one of the following diet for at least 3 years: vegan vegetarian omnivorous Study will focus into the differences in dermal protein density and dermal thickness, skin hydration and trans-epidermal water loss. Study will focus also into body composition, specifically into % of body fat and % of lean body weight.

Official Title
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The Influence of the Nutritional Status of Women Between 30 and 45 Years of Age on the Condition of the Skin and Body Composition

Conditions
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Skin Condition, Body Composition

Intervention / Treatment
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* Other: dietary habit


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: women aged 30-45 years vegan or vegetarian or omnivorous diet for at least 3 years, body mass index (BMI) between 18.5 and 25. Exclusion Criteria: smoking or have smoked in the past (quit less than 3 years ago), pregnancy or breastfeeding, pre-menopause medications that increase skin dryness (e.g. retinoids), visiting solariums, visiting of the fitness center more than 3 times a week, regular consumption of protein supplements (including food supplements with collagen), chronic and acute skin diseases, chronic and acute diseases of the gastrointestinal tract (e.g. celiac disease), lactose intolerance, various diets (e.g. health, slimming), damaged skin in the test area (inner forearm), hyperhidrosis or increased sweating, diseases that cause a chronically damaged skin barrier (e.g. atopic dermatitis, ichthyosis), cancer diseases, pacemaker.

Ages Eligible for Study
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Minimum Age: 30 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Vegans<br>In this group women aged 30-45 years that follow vegan diet for at least 3 years will be included. | Other: dietary habit<br>* As it is observational study, women that follow three different dietary patterns will be inlcuded .<br>|
| Vegetarians<br>In this group women aged 30-45 years that follow vegetarian (lacto-ovo/lacto/ovo) diet for at least 3 years will be included. | Other: dietary habit<br>* As it is observational study, women that follow three different dietary patterns will be inlcuded .<br>|
| Omnivores<br>In this group women aged 30-45 years that follow omnivorous diet for at least 3 years will be included. | Other: dietary habit<br>* As it is observational study, women that follow three different dietary patterns will be inlcuded .<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Dermal density | It will be measured on forearm using ultrasonography as score 0-100. | baseline | 
| Dermal thickness | It will be measured on forearm using ultrasonography in micrometeres. | baseline | 
| Skin hydration | It will be measured on forearm using Cortex DermaLab flat hydration probe in microsiemens. | baseline | 
| Skin elasticity | It will be measured on forearm using Cortex DermaLab elasticity probe in MPa. | baseline | 
| Trans epidermal water loss | It will be measured on forearm using Cortex DermaLab open-chamberTEWL probe. | baseline | 
| % of lean body weight | It will be measured using Multiscan is a spectroscopy (BIS). | baseline | 
| % of body fat | It will be measured using Multiscan is a spectroscopy (BIS). | baseline |