Effects of Pre-Exercise Nutrition Strategies on Body Temperature and Thermoregulatory Responses

Study Overview
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Brief Summary
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Carbohydrate ingestion, in particular fructose, has been shown in a handful of previous studies to elicit a thermic effect and increase core body temperature after ingestion. Carbohydrate foods and supplements are commonly consumed prior to endurance running competition, including situations where an athlete's ability to dissipate body heat is compromised. Thus, there is some potential for pre-exercise carbohydrate ingestion to have a deleterious effect on body heat regulation in hot and humid environments. Thus, this projects aims to study the effects of pre-exercise carbohydrate ingestion on core body temperature, perceived thermal stress, and perceived exertion during high-intensity running.

Official Title
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Effects of Pre-Exercise Nutrition Strategies on Body Temperature and Thermoregulatory Responses

Conditions
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Impaired Thermoregulation

Intervention / Treatment
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* Other: Carbohydrate Beverage
* Other: Placebo Beverage


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Be currently running ≥20 miles per week Have a projected 5-km maximal effort running time between 16:00-23:00 minutes Exclusion Criteria: Any gastrointestinal disorders that cause swallowing problems or frequent nausea/vomiting

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Carbohydrate Beverage<br> | Other: Carbohydrate Beverage<br>* 750 ml of a 13.5% carbohydrate (sucrose) beverage<br>|
| Placebo Comparator: Placebo Beverage<br> | Other: Placebo Beverage<br>* 750 ml of an artificially-sweetened beverage<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Core Body Temperature | Core body temperature will be measured with a ingestible pill thermometer. Readings will be taken during a 60 minute rest period and at 1-km intervals during a 5-km run. | 80 minutes (60, 50, 40, 30, 20, and 10 min pre-run and at 1-km intervals during a 20 min 5-km run) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Thermal Sensation Scale | The Thermal Sensation Scale is a 0-8 numerical rating scale with descriptors of unbearably cold at 0, neutral at 4, and unbearably hot at 8. These ratings will be collected during a 60 minute rest period and at 1-km intervals during a 5-km run. | 80 minutes (60, 50, 40, 30, 20, and 10 min pre-run and at 1-km intervals during a 20 min 5-km run) | 
| Feeling Scale | The Feeling Scale is a bipolar numerical rating scale ranging from -5 to +5, with descriptors of very bad at -5, neutral at 0, and very good at +5. These ratings will be collected during a 60 minute rest period and at 1-km intervals during a 5-km run. | 80 minutes (60, 50, 40, 30, 20, and 10 min pre-run and at 1-km intervals during a 20 min 5-km run) | 
| Rating of Perceived Exertion | These ratings will be collected during a 60 minute rest period and at 1-km intervals during a 5-km run. | 80 minutes (60, 50, 40, 30, 20, and 10 min pre-run and at 1-km intervals during a 20 min 5-km run) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Exercise