Postoperative Pain Endodontic Retreatment

Study Overview
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Brief Summary
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To compare the incidence of post-operative pain after single-visit versus two-visit non-surgical endodontic retreatment.

Detailed Description
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Post treatment failure could be treated by two options including orthograde retreatment and apical surgery . In a previous study, orthograde retreatments presented a success rate of 81 % classified as healed and 93 % as no symptoms and fully functional. In a systematic review, it has also been concluded that endodontic surgery offers more favorable initial success but orthograde retreatment yields to a better long-term outcome . Although early results of single-visit treatments are contradictory ; Completing the treatment in a single appointment reduces the treatment time and cost, decreases micro leakage risk and avoids recontamination of root canals between appointments in multiple-visit treatments . Again, reviewing the literature concerning primary treatment showed that, no significant differences were observed in healing of periapical radiolucency between teeth treated in single-visit and those treated in two-visits. Even, after using calcium hydroxide for four weeks . The presence of a positive bacterial culture at the time of filling did not influence the outcome of treatment . Thorough online search revealed that, few studies are found concerning post- operative pain after single visit retreatment . The present study is designed to compare the effects of single-visit and two-visit root canal treatments on postoperative pain in retreatment cases. The primary outcome measure of this study is proposed to be whether single-visit root canal retreatment influenced the occurrence of postoperative pain as compared to two-visit treatment.

Official Title
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Incidence Postoperative Pain After Single Visit Versus Two Visit Nonsurgical Endodontic Retreatment

Conditions
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Endodontically Treated Teeth

Intervention / Treatment
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* Other: Non-surgical endodontic retreatment in single visit


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Clinically asymptomatic. Previously treated teeth in need of retreatment due to leakage and/or improper filling. No periapical radiolucency. No percussion pains. Age 20 - 45. Premolar teeth. Male & female. Exclusion Criteria: Complicating compromised patient. Tenderness to percussion and acute apical abscess. Presence of an associated sinus tract. Presence of swelling in adjacent soft tissue. Teeth with periodontal pathologies or mobility. Teeth representing root fracture. Pregnant women. If analgesics or antibiotics have been administrated by the patient during the past 24 hours.

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: group 1 Non-surgical endodontic retreatment in single visit<br>Single visit treatments have gained more popularity. Completing the treatment in a single appointment has many advantages including reduction in treatment time and cost, lower risk of micro leakage and recontamination of root canals between appointments | Other: Non-surgical endodontic retreatment in single visit<br>* Full medical and dental history using a schematic dental chart, will be obtained from all patients treated during this study.<br>* Other names: Non-surgical endodontic retreatment in Two-visit;|
| Active Comparator: group 2 Non-surgical endodontic retreatment in Two-visit<br>Two-visit endodontic treatment with intra-canal medication was traditionally found to be effective in decreasing the number of flare-up in all retreatment cases and in reducing postoperative pain of previously symptomatic teeth | Other: Non-surgical endodontic retreatment in single visit<br>* Full medical and dental history using a schematic dental chart, will be obtained from all patients treated during this study.<br>* Other names: Non-surgical endodontic retreatment in Two-visit;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence and intensity of postoperative | Evaluate incidence and intensity of postoperative pain at 6,12,24, 48hours , and one week using numerical visual scale (NRS) after each visit endodontic retreatment | At one week after each visit | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of analgesic tablets | Number of analgesic tablets taken by the patient after endodontic retreatment | baseline |