Comparison of Bi-level Erector Spine Plane Block and Combined Pectoral I-II Block in Breast Surgery

Study Overview
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Brief Summary
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In this study, we compared ultrasound-guided modified pectoral nerve (PECS) block and bi level erector spinae plane (ESP) block on postoperative analgesic effect in breast surgery.

Detailed Description
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After being informed about the study and potential risks, written consent was obtained from all patients. Patients who meet eligibility requirements will be randomized in a 1:1 ratio to bi- level erector spinae plane block and modified pectoral block.

Official Title
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Comparison of Postoperative Efficacy of Ultrasound-guided Bi-level Erector Spine Plane Block and Combined Pectoral I-II Block in Breast Cancer Surgery

Conditions
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Postoperative Pain, Analgesia

Intervention / Treatment
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* Other: Ultrasound guided bi-level erector spinae plane block
* Other: Ultrasound guided modified pectoral nerve block


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: American Society of Anesthesiologists Classification (ASA) I-II patients 18-70 aged patients patients who scheuled elective breast cancer surgery Exclusion Criteria: American Society of Anesthesiologists Classification (ASA) III-IV patients patients with coagulopathy patients with infection at the injection site

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Bi-level erector spinae plane block<br>Bi-level ultrasound (US)-guided Erector spinae plane block (ESP) with 30 ml 0.25% bupivacaine at the T2 andT4 vertebral level will performe preoperatively to all patients in the ESP group. | Other: Ultrasound guided bi-level erector spinae plane block<br>* Bi-level ultrasound (US)-guided Erector spinae plane block (ESP) with 30 ml 0.25% bupivacaine at the T2 andT4 vertebral level will performe preoperatively to all patients in the ESP group.<br>|
| Experimental: Modified pectoral nerve block<br>Ultrasound (US)-guided modified pectoral nerve block (PECs) with 30 ml 0.25% bupivacaine will performe preoperatively to all patients in the PECs group. | Other: Ultrasound guided modified pectoral nerve block<br>* Ultrasound (US)-guided modified pectoral nerve block (PECs) with 30 ml 0.25% bupivacaine will performe preoperatively to all patients in the PECs group.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Morphin consumption | Patients in both groups will provide with intravenous patient-controlled analgesia device containing morphine for postoperative analgesia. | during postoperative 24 hour | 
| numerical rating scale (NRS) | A numerical rating scale (NRS) requires the patient to rate their pain on a defined scale. For example, 0-10 where 0 is no pain and 10 is the worst pain imaginable | during postoperative 24 hour | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Regional anaesthesia, Erector spinae plane block, PECs blocks, Breast cancer surgery