Effect of Superficial Cervical Plexus Block on the Postoperative Quality of Recovery

Study Overview
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Brief Summary
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Pain and discomfort after anterior cervical spine surgery is difficult to quantify and quoted as moderate in severity, often needing oral opioid analgesics. In addition, these patients are more prone for postoperative respiratory complication due to airway edema secondary to surgical retraction or wound hematoma. Opioid analgesics provide good pain control but postoperative nausea and vomiting and respiratory depression are undesirable in these patients who are at risk for postoperative wound hematoma and airway edema The use of multimodal analgesia is rapidly becoming the 'standard of care' for preventing pain after ambulatory procedures at most surgery centers throughout the world . The purpose of this study is to determine whether superficial cervical plexus block will improve the postoperative quality of recovery as measured by Quality of Recovery 40 questionnaire (QoR-40) in patients undergoing elective anterior cervical discectomy and fusion.

Detailed Description
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Anterior cervical discectomy and fusion is increasingly being done as a day surgery or short stay surgery. Postoperative pain is the leading cause of unplanned hospital admissions following day surgery, a major source of dissatisfaction and often impairs the quality of recovery. Opioid analgesics alone are not always effective and may also worsen the postoperative nausea and vomiting and in turn the postoperative recovery. This study is designed to find out if an injection of freezing on the side of neck around the nerves (superficial cervical plexus block) improves the quality of recovery from anesthesia and surgery by reducing the pain, analgesic consumption after anterior cervical spine surgery. Primary Outcome Measure The primary outcome measure is the global QoR-40 aggregate score at 24 hours after surgery. Secondary Outcome Measures Postoperative pain scores (first 24 hours) Total analgesic consumption (first 24 hours) Time for first opioid administration Postop Nausea and vomiting (first 24 hours) Post operative sedation (first 24 hours)

Official Title
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Effect of Superficial Cervical Plexus Block on the Postoperative Quality of Recovery After Anterior Cervical Discectomy and Fusion

Conditions
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Cervical Disc Prolapse

Intervention / Treatment
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* Other: Superficial cervical plexus block for experimental group


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: all adult patients aged 18-80 years with ASA class I - III undergoing anterior cervical disc surgery in supine position Exclusion Criteria: In patients who are allergic to local anesthetics ASA- IV patients Lack of informed consent Pregnant patient

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: superficial cervical plexus block<br>superficial cervical plexus block for experimental group | Other: Superficial cervical plexus block for experimental group<br>* 15 ml of 0.25% Bupivacaine will be given for superficial cervical plexus block<br>|
| No Intervention: No Block<br>no superficial cervical plexus block for the no intervention group | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The primary outcome measure is the global QoR-40 aggregate score after ACDF surgery. |  | 24 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| post operative pain score assessment |  | 24 hours | 
| Post operative analgesic consumption |  | 24 hours | 
| time for the first dose of opioid consumption |  | 24 hrs | 
| post operative nausea and vomiting |  | 24 hrs | 
| post operative sedation score |  | 24 hrs | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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superficial cervical plexus block, quality of recovery