Air Pollution and COPD Exacerbation

Study Overview
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Brief Summary
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There is an excess of hospitalization rates for acute exacerbation of COPD in Picardy compared to the national data. A first study realized in Picardy has shown a link between air quality and COPD. Nevertheless, the particles type is unknown and according to it, impact on COPD could be different. The investigator goal is to find a correlation between acute exacerbation of COPD consultation rate and daily ultra thin particles in Haut de France. The investigators will correlate the particles composition with daily acute exacerbation of COPD rate. All COPD patients with a diagnosis of acute exacerbation in emergency room in University Hospital of Amiens-Picardie and Lille, and Clinique de l'Europe between 01/01/2020 and 31/12/2020 will be included. For each patient, home and work address will be collected. The duration of 1 year was chosen to take into account seasonal variations. In parallel, a daily report of the rate of ozone, particles (PM2.5 and PM10), dioxide nitrogen but also odours and pollens will be done by ATMO Haut de France.

Official Title
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Impact of Air Pollution on Chronic Obstructive Pulmonary Disease (COPD) Exacerbation in Haut de France. BePoPi Project.

Conditions
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Chronic Obstructive Pulmonary Disease, Pollution; Exposure

Intervention / Treatment
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* Other: collection of data about each acute exacerbation of COPD


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: COPD patients with a diagnosis of acute exacerbation of COPD in the emergency room of Amiens and Lille centers Adults Patients able to express consent signed written informed consent form covered by national health insurance Exclusion Criteria: patients non covered by national health insurance patients not able to express consent minors

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: collection of data about each acute exacerbation of COPD|COPD is chronic obstructive pulmonary disease. Data collected are need of hospitalisation, final diagnosis, home address, work address and air quality data.|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| daily rate of COPD exacerbation consultation in the emergency room of the 3 centers | daily rate of COPD exacerbation consultation in the emergency room of the 3 centers | every day during 12 months | 
| ultrathin particles quantity in the air | ultrathin particles quantity will be determined by the air of Haut de France by the company ATMO Haut de France. | every day during 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| chemical composition ultrathin particles | chemical composition ultrathin particles will be determined by the air of Haut de France by the company ATMO Haut de France. | every day during 12 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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pollution, Chronic Obstructive Pulmonary Disease, ultrathin particles