Vitamin D and Sleep Disorders in Pregnancy

Study Overview
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Brief Summary
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Lack of sleep and poor sleep quality in pregnant women are associated with maternal depression and cognitive-sensual irregularities. These irregularities were reported worsening women's life quality and even increasing suicide ideation. It is also associated with obstetrical complications such as fetal growth deficiency, preterm birth, prolonged labor, preeclampsia and increased abdominal delivery frequency.Vitamin D also may affect the sleep indirectly through the cases with nonspecific pains. It was reported that vitamin D levels are correlated with sleep disorders such as obstructive sleep apnea and restless legs syndrome. The primary purpose of this study is to examine sleep disorders and vitamin D levels in pregnant women, and also, secondarily, vitamin D - anxiety and sleep disorders - anxiety relations were assessed.

Official Title
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Do Low Vitramin D Levels Increase the Frequency of Sleep Disorders and Anxiety in the 2nd and 3rd Trimester?

Conditions
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Sleep Disorder, Pregnancy Related, Vitamin D Deficiency

Intervention / Treatment
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* Behavioral: Behavioral scales were used


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: singletone pregnant women second and third trimester pregnant women Exclusion Criteria: psychiatric disorder sleep disorder

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Pregnant women between 18-45 years old, being in second and third trimester of a singleton pregnancy<br> | Behavioral: Behavioral scales were used<br>* Women's Health Initiative Sleeplessness Scale (WHISS) and State Anxiety Scale (SAS), were applied.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Health Initiative Sleeplessness Scale (WHISS) | Women's Health Initiative Sleeplessness Scale (WHISS) was used to assess the sleep status of pregnant women. In this scale consisting of five questions, first four questions focus on the period of time when sleeplessness started, status of not being able to continue the sleep and waking up early in the morning, while the last one focusses to determine the sleep quality. Scores of the scale range between 0 - 20. A score equal and above 10 means a sleeplessness problem. An increase in score means intensifying the sleeplessness symptoms. | Through study completion, an average of 1 year | 
| State Anxiety Scale (SAS) | In anxiety screening of pregnant women, State Anxiety Scale (SAS) was used. Scores of the scale including twenty questions range between min. 20 and max. 80. Higher scores mean higher anxiety. | Through study completion, an average of 1 year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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anxiety, Pregnancy,, Sleep Wake Disorders, Vitamin D