Living Conditions and Breast Cancer

Study Overview
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Brief Summary
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The main objective of this study is to estimate of the link (odds ratio) between the precariousness defined by the score SPICE (2 groups: precarious and insecure) and stage at diagnosis (2 groups: CAS: stages 1 or 2 the good prognosis versus the witnesses: stage 3 or 4 bad prognosis).

Detailed Description
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Our secondary objectives include: To study the link between cancer stage at diagnosis and diverse parameters describing living conditions To construct a new score for social fragility based on new data collected in this study, and to compare this score with the EPICES score To study patient quality of life at study baseline

Official Title
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Living Conditions and Breast Cancer

Conditions
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Breast Neoplasms

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria (for cases): Patient has been correctly informed about the study, and agrees to participate The patient must be insured or beneficiary of a health insurance plan Incident breast cancer cases (diagnosis based on pathology) excluding sarcoma, classifiable as stage III-IV, surgical cases Inclusion Criteria (for controls): Patient has been correctly informed about the study, and agrees to participate The patient must be insured or beneficiary of a health insurance plan Incident breast cancer cases (diagnosis based on pathology) excluding sarcoma, classifiable as stage I-II, surgical cases Exclusion Criteria (for cases and controls): The patient is in an exclusion period determined by a previous study The patient is under judicial protection, under tutorship or curatorship The patient is pregnant, parturient, or breastfeeding The patient is opposed to study participation Women not able to answer a questionnaire due to language barriers or due to vascular or degenerative cerebral dysfunction It is impossible to correctly inform the patient
Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Cases - Stage III-IV breast cancer<br>The women in this group have been diagnosed with stage III-IV incident cancer. | |
| Controls: Stage I-II breast cancer<br>The women in this group have been diagnosed with stage I-II incident cancer. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The odds ratio for having a stage I-II diagnosis versus a stage III-IV diagnosis according to EPICE score category (social fragility versus no social fragility). | The main criterion is the estimation of the link (odds ratio) between the precariousness defined by the score SPICE (2 groups: precarious and insecure) and stage at diagnosis (2 groups: CAS: stages 1 or 2 the good prognosis versus the witnesses: stage 3 or 4 bad prognosis). | Baseline (Day 0; cross-sectional study) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Breast cancer, living conditions, social fragility