LUS in Acute Heart Failure Therapeutic Adaptation

Study Overview
=================
Brief Summary
-----------------
Evaluate lung ultrasound aspect according to diuretics dosage evolution in patients hospitalized for acute heart failure.

Detailed Description
-----------------
EPPICA is an observational and prospective cohort study. The study goal is to evaluate LUS aspect evolution according to diuretics dosage in patients hospitalized for acute heart failure.

Official Title
-----------------
Interest of Lung Ultrasound (LUS) in Therapeutic Adaptation of Patients Hospitalized in Medical Department for Acute Heart Failure (AHF).

Conditions
-----------------
Acute Heart Failure, Pulmonary Congestion

Intervention / Treatment
-----------------
* Other: Lung ultrasound


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Acute heart failure diagnosed by a senior physician in the medical department, with a confirmation of a second senior physician. Hospitalised in the medical department. No objection from the patient of his trusted person. Exclusion Criteria: Administrative supervision or deprived of their liberty Pulmonary conditions distracting lung ultrasound (pneumonectomy, pulmonary fibrosis) Chronically dialysed

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients with acute heart failure<br>Patients hospitalized for acute heart failure in medical department. | Other: Lung ultrasound<br>* We will perform daily a lung ultrasound to evaluate pulmonary congestion by counting B-lines.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Lung ultrasound aspect according to diuretics dosage evolution. | B-lines number on LUS | LUS will be performed daily during the whole hospitalisation length (on average 7 days). | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Lung ultrasound aspect according to clinical signs of acute heart failure (crackling auscultation or lower limbs edema) | B-lines number on LUS | LUS and clinical examination will be performed daily during the whole hospitalisation length (on average 7 days). | 
| Lung ultrasound aspect according to acute kidney injury (based on plasmatic creatinine levels). | B-lines number on LUS | LUS will be performed daily during the whole hospitalisation length (on average 7 days). Plasmatic creatinine measure will be performed at least weekly. | 
| Lung ultrasound aspect according to early prognosis (re-hospitalisation or mortality within 30 days after discharge) | B-lines number on LUS | LUS will be performed daily during the whole hospitalisation length (on average 7 days). Patient will be called 30 days after discharge. | 
| Feasibility of daily LUS in medical department. | Number of LUS performed compared to number of hospitalisation days. | LUS will be performed daily during the whole hospitalisation length (on average 7 days). | 
| Interest of LUS compared to clinical examination at discharge. | B-lines at discharge compared to clinical signs of acute heart failure. | LUS and clinical examination will be performed daily during the whole hospitalisation length (on average 7 days). | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Lung Ultrasound, Diuretics, Medical department