the Related Factors of Bariatric Surgery on Lipidemia

Study Overview
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Brief Summary
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Obesity and related metabolic diseases have become a chronic disease that is a threat to human health. Bariatric surgery can effectively and long-term reduce excess body weight and relieve related metabolic diseases, including type 2 diabetes. Laparoscopic gastric bypass surgery and laparoscopic sleeve gastrectomy are commonly used in bariatric surgery. Laparoscopic sleeve gastrectomy due to simple operation, good weight loss, and metabolic disease control effect, which is more widely used. However, there are several studies that show an increased chance of gastroesophageal reflux disease after laparoscopic sleeve gastrectomy. Long-term gastroesophageal reflux may lead to Barrett's esophagus or esophageal cancer. Nowadays, the cause of gastroesophageal reflux disease after sleeve gastrectomy is not clear and precautionary measures are not precise. In this study, prospective randomized controlled trials were conducted to explore the possible change of lipidemia after bariatric surgery and to explore ways to prevent bariatric surgery after bariatric surgery.

Official Title
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The Impact of Bariatric Surgery on Estimated Lipidemia in Chinese Obesity Patients: a Retrospective Cohort Study

Conditions
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Bariatric Surgery, Lipidemia

Intervention / Treatment
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* Procedure: sleeve gastrectomy
* Procedure: gastric bypass


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: -For the choice of surgical approach, numerous studies have shown that BMI ≧ 45, the general choice of gastric bypass surgery, BMI <45, you can choose sleeve gastrectomy. The remission rate for T2DM, sleeve gastrectomy has a good result for young patients with shorter duration. In the investigator's country, the BMI less than 45 is majorities. Exclusion Criteria: -BMI<27.5

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Lipidemia<br> | Procedure: sleeve gastrectomy<br>* sleeve gastrectomy.<br>Procedure: gastric bypass<br>* gastric bypass<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| preoperative of choleaterol | choleaterol in ml/dl | Preoperate | 
| Postoperative of choleaterol at 3 months | choleaterol in ml/dl | 3 months | 
| Postoperative of choleaterol at 6 months | choleaterol in ml/dl | 6 months | 
| Postoperative of choleaterol at 1 year | choleaterol in ml/dl | 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Preoperative of triglyceride | triglyceride in ml/dl | Preoperative | 
| Postoperative of triglyceride at 3 months | triglyceride in ml/dl | 3 months | 
| Postoperative of triglyceride at 6 months | triglyceride in ml/dl | 6 months | 
| Postoperative of triglyceride at 1 year | triglyceride in ml/dl | 1 year |