Percutaneous Aponeurotomy in the Treatment of Dupuytren's Disease

Study Overview
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Brief Summary
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The efficiency of percutaneous aponeurotomy in the treatment of Dupuytrens disease is well known. However, the duration of the clinical improvement after aponeurotomy is not well known. This study aims primarily at measuring the incidence rate of local relapse of Dupuytrens-induced finger flessum, within two years following treatment by percutaneous aponeurotomy in Dupuytrens.

Conditions
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Dupuytren Disease

Intervention / Treatment
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* Procedure: Percutaneous aponeurotomy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patient suffers from Dupuytren disease Patient has at least one finger with at least 20° flessum on the metacarpophalangeal joint and/or on the proximal interphalangeal joint Patient has chosen to benefit from local treatment Exclusion Criteria: Pregnancy Breastfeeding No social insurance

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Percutaneous aponeurotomy<br>Treatment of Dupuytrens-induced finger flessum using percutaneous aponeurotomy | Procedure: Percutaneous aponeurotomy<br>* The finger(s) with limited extension due to Dupuytrens disease and for which the patient desires treatment, will be treated by fine-needle percutaneous aponeurotomy under local anesthesia (outpatient procedure). This procedure is already routinely used in clinical practice ; our study aims at better describing the time-sustainability of its benefits.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Frequency of local relapse at 24 months | the statistical unit is the finger treated by aponeurotomy (we expect an average of 2 fingers treated for one patient included). Local relapse is defined as the recurrence of a finger flessum superior by 20° to the articular range initially obtained after aponeurotomy | 24 months after treatment by aponeurotomy | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Primary success rate of aponeurotomy | the statistical unit is the finger treated by aponeurotomy (we expect an average of 2 fingers treated for one patient included). Complete success is defined as a finger flessum inferior to 5° | 3 months after treatment | 
| Frequency of local relapse at 12 months |  | 12 months after treatment by aponeurotomy | 
| Frequency of local relapse at 36 months |  | 36 months after treatment by aponeurotomy | 
| Frequency of local relapse at 48 months |  | 48 months after treatment by aponeurotomy | 
| Frequency of local relapse at 60 months |  | 60 months after treatment by aponeurotomy |