Effects of Femoral vs Saphenous Nerve Blocks on Function After ACL Repair

Study Overview
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Brief Summary
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The primary objective of the study is to compare motor strength in knee extension between two groups of patients. One group receiving a proximal thigh block of the femoral nerve, and one receiving a distal thigh block of the saphenous nerve. The secondary objective is to compare the pain relief and functional outcomes in these two groups.

Official Title
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Effects of Femoral Versus Saphenous Nerve Blocks on Knee Extensor Strength, Pain, and Patient-Perceived Physical Function Following ACL Reconstruction

Conditions
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Anterior Cruciate Ligament

Intervention / Treatment
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* Procedure: nerve block


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 18-65 Upcoming ACL reconstruction using patellar tendon autograft scheduled at Hershey Medical Center or the Hershey Outpatient Surgical Center (HOSC) Exclusion Criteria: Documented neuropathy Skeletally immature Previous knee surgery Inability to provide informed consent ACL reconstruction with other tendon repairs

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: proximal nerve block<br>The anesthesiologist will administer a proximal nerve block if specified in the randomization envelope. | Procedure: nerve block<br>* A nerve block performed as per standard of care: femoral nerve blocks, and saphenous nerve blocks performed more distally (within 10cm superior to the adductor tubercle).<br>|
| Active Comparator: distal nerve block<br>The anesthesiologist will administer a distal nerve block if specified in the randomization envelope. | Procedure: nerve block<br>* A nerve block performed as per standard of care: femoral nerve blocks, and saphenous nerve blocks performed more distally (within 10cm superior to the adductor tubercle).<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| strength of knee extensors | Extensor testing will be conducted in both legs using a hand held dynamometer. | change from baseline preoperatively at 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| pain level and functional outcomes | Medical record will be reviewed for type and amount of in hospital post operative medication and levels, then assessed by PROMIS survey at follow up appointments. | change from in hospital post-operative period at 12 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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nerve blocks in Anterior cruciate ligament surgery