Impact of Long COVID-19 on the Health and Quality of Life of Military Personnel (Active or Retired) and Their Families

Study Overview
=================
Brief Summary
-----------------
Severe and sometimes irreversible sequelae are observed in people who have developed a severe form of COVID-19 (pulmonary, cardiovascular, renal, neurological sequelae among others). More than 10% of individuals who contracted the disease, even in a mild form, still have at least one of the initial symptoms at six months, also known as prolonged symptoms or long COVID syndrome. The most frequently observed symptoms are asthenia, neurological disorders (headache, anosmia, ageusia, etc.), cardio-thoracic disorders, pain, digestive or skin disorders. Very recently, the first results of a British prospective cohort study (PHOSPCovid) indicate that more than half of the COVID-19 survivors who were hospitalised experienced a very severe to moderate deterioration in their mental and/or physical health five months after hospitalisation. Women are particularly affected. Another American study shows that 85% of non-hospitalised COVID-19 patients developed at least 4 neurological symptoms impacting their quality of life. The most common are: brain fog (81%), headaches (68%), numbness or tingling (60%), taste impairment (59%) and loss of smell (55%). These disabling symptoms may persist for weeks or months, deteriorating the quality of life of patients and making it difficult for some to return to a normal life. On the basis of current knowledge concerning the long-term sequelae of SARS-CoV-2 infection, it seems necessary to offer these subjects a specific care pathway and to adapt their living and working conditions beyond their medical care. The present study is aimed at measuring the impact of long COVID on the health and quality of life of the defence community (military personnel and their families).

Official Title
-----------------
Impact of Long COVID-19 on the Health and Quality of Life of Military Personnel (Active or Retired) and Their Families

Conditions
-----------------
COVID-19

Intervention / Treatment
-----------------
* Other: Online questionnaire
* Other: Semi-structured interview


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age ≥ 18 years-old Be affiliated to the French military health insurance Exclusion Criteria: Age < 18 years-old

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| COVID+<br>Participants who have experienced COVID-19 | Other: Online questionnaire<br>* Participants will be asked to complete an online questionnaire about their health and quality of life since the start of the pandemic.<br>Other: Semi-structured interview<br>* 20 participants (10 from each group) will be randomly selected to participate in a semi-structured interview focusing on their perception of their health and quality of life since the start of the pandemic.<br>|
| COVID-<br>Participants who have not experienced COVID-19 | Other: Online questionnaire<br>* Participants will be asked to complete an online questionnaire about their health and quality of life since the start of the pandemic.<br>Other: Semi-structured interview<br>* 20 participants (10 from each group) will be randomly selected to participate in a semi-structured interview focusing on their perception of their health and quality of life since the start of the pandemic.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prevalence of mental health events | Prevalence of mental health events will be calculated in each group, the compared: number of participants who report having experienced a mental health event (e.g. anxiety disorder) divided by the number of participants. | Until the end of the study (12 months) | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
quality of life, long COVID