GRAFted Patients' anxieTY Report

Study Overview
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Brief Summary
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Autograft is a technique requiring several weeks of hospitalization in a protected environment and can be a source of anxiety of different natures for patients. In this study, level of anxiety will be reported weekly throughout hospitalizations for autologous transplant, to detect the most stressful period.

Detailed Description
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Autograft is one of hematological malignancies treatment, such as lymphoma and myeloma. This technique requires several weeks of hospitalization in a protected environment and can be a source of anxiety of different natures for patients. According to the medical and scientific report of the Biomedicine Agency in 2016, 3 043 patients were involved in an autologous transplant, which represents a significant number of patients potentially exposed to these types of anxiety. That is why it will be interesting in this study to report weekly the level of anxiety throughout their hospitalization for the autologous transplant, to detect the most stressful period. A validated questionnaire will be used: the HAD (Hospital Anxiety and Depression) scale of anxiety and depression.

Official Title
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GRAFted Patients' anxieTY Report (GRAFTY)

Conditions
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Autologous Transplant Indication

Intervention / Treatment
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* Other: HAD (Hospital Anxiety and Depression) scale


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Autograft indication according to the Multidisciplinary Concertation Meeting Exclusion Criteria: Incapacity to complete surveys

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Autografted patients<br>Patients hospitalized in the hematological department of the Institute will complete the first day of conditioning and then weekly HAD (Hospital Anxiety and Depression) scale. | Other: HAD (Hospital Anxiety and Depression) scale<br>* HAD (Hospital Anxiety and Depression) scale will be completed and reported by patients the first day of conditioning and then weekly from day 0 corresponding to the autograft, until their last day in the hematological department.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Anxiety and depression measure | The aim of this study is to measure patients anxiety and depression, using the HAD : Hospital Anxiety and Depression scale. Scores of the HAD scale can be defined as: By adding the points of the answers: 1, 3, 5, 7, 9, 11, 13: we obtain the Total A which corresponds to the measure of the anxiety, then: 7 or less: absence of symptomatology; 8 to 10: doubtful symptomatology; 11 and above: certain symptomatology. By adding the points of the answers: 2, 4, 6, 8, 10, 12, 14: we obtain the Total B which corresponds to the measure of the depression, then: 7 or less: absence of symptomatology; 8 to 10: doubtful symptomatology; 11 and above: certain symptomatology. The minimal score is 0 and the maximal total score is 42. | 30 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Autograft, Anxiety, Protected environment