The Effects of Sleep Deprivation on Physiological and Perceptual Responses During Exercise

Study Overview
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Brief Summary
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Sleep deprivation has been found to impact exercise performance. The effects of both partial (several hours) and full (24+ hours) sleep deprivation on exercise performance has shown effects on rating of perceived exertion, rate of oxygen consumption, respiratory exchange ratio, and heart rate. A common practice with athletes is to perform regular physiological testing (submaximal and maximal) in order to assess their fitness and to determine training intensities. However, the effects of sleep deprivation on those same physiological test results has not been investigated Therefore, the purpose of this study is to investigate the effects of partial sleep deprivation on physiological test results.

Official Title
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The Effects of Partial Sleep Restriction on Physiological and Perceptual Responses During Submaximal and Maximal Exercise in Trained Runners

Conditions
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Sleep Deprivation

Intervention / Treatment
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* Other: Sleep deprivation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Injury-free, trained, male runners Exclusion Criteria: Female, untrained, injured

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Sleep deprivation<br>Two hours of sleep deprivation (Six hours of sleep) | Other: Sleep deprivation<br>* Participants wake after six hours so that they are deprived of 2 hours of sleep<br>|
| No Intervention: No intervention<br>No sleep deprivation (Eight hours of sleep) | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Oxygen uptake | Change from baseline in oxygen uptake measured breath-by-breath using an online gas analyzer during submaximal and maximal incremental exercise | From baseline to completion, up to 31 days | 
| Respiratory exchange ratio | Change from baseline in respiratory exchange ratio measured breath-by-breath using an online gas analyzer during submaximal and maximal incremental exercise | From baseline to completion, up to 31 days | 
| Breathing frequency | Change from baseline in breathing frequency measured breath-by-breath using an online gas analyzer during submaximal and maximal incremental exercise | From baseline to completion, up to 31 days | 
| Minute ventilation | Change from baseline in minute ventilation measured breath-by-breath using an online gas analyzer during submaximal and maximal incremental exercise | From baseline to completion, up to 31 days | 
| Blood lactate concentration | Change from baseline in blood lactate concentration measured using capillary puncture during submaximal and maximal incremental exercise | From baseline to completion, up to 31 days | 
| Rating of perceived exertion | Change from baseline in ratings of perceived exertion measured using a 15-point (6-20) scale during submaximal and maximal incremental exercise | From baseline to completion, up to 31 days | 
| Heart rate | Change from baseline in heart rate measured using a heart rate monitor during submaximal and maximal incremental exercise | From baseline to completion, up to 31 days |