The Effect of Video and Traditional Laryngoscopy on Hemodynamic Response in Hypertensive and Normotensive Patients

Study Overview
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Brief Summary
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During endotracheal intubation, it is known that la laryngoscopy has significant effects, such as tachycardia and blood pressure increase, which may be harmful, especially in those with cardiovascular disease. Different studies comparing laryngeal stimulation and there resulting hemodynamic response made with various intubation devices are available in the literature. The investigators planned to work with the hypothesis that endotracheal intubation with videolaryngoscopy would have less hemodynamic response traditional (Macintosh) laryngoscopy and the use of videolaryngoscopy would result in wider vision with less laryngeal stimulation.

Detailed Description
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In this study, in a study on endotracheal intubation under general anesthesia, a routine preparation of endotracheal intubation using video laryngoscopy or Macintosh laryngoscopy in adult hypertensive and normotensive patients between 18-75 years old, form will be written and recorded. Patient age, weight, height, sex, operation, co-morbid conditions and vital findings, measurements used in airway evaluation, initial trial success, laryngoscope using number of procedures, intubation tube number will be recorded. Statistical analysis was performed using statistical program to compare the hemodynamic response of hypertensive and normotensive patients using videolaryngoscope or Macintosh laryngoscope

Official Title
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The Effect of Video and Traditional Laryngoscopy on Hemodynamic Response in Hypertensive and Normotensive Patients

Conditions
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Intubation, Anesthesia, Hypertension

Intervention / Treatment
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* Device: Macintosh laryngoscopy
* Device: C-Mac Videolaryngoscope


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age: 18-75 years. Underwent surgery under general anesthesia. Exclusion Criteria: ASA (American Society of Anesthesiologists) IV, V patients Preoperative systolic blood pressure 180 mmHg, diastolic blood pressure a pressure above 110 mmHg. Ejection fraction is less than 40%. Difficult intubation history Mallampati 3,4

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Crossover Assignment
Interventional Model Description: Prospective
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Hypertensive T group<br>Hypertensive T group: Patients participating in the study were randomly assigned hypertensive (preoperative systolic blood pressure <180 mmHg and diastolic blood pressure <100 mmHg) Macintosh laryngoscopy using intubated | Device: Macintosh laryngoscopy<br>* Endotracheal intubation time using the Macintosh laryngoscope<br>|
| Active Comparator: Hypertensive VL group<br>Hypertensive VL group: Patients participating in the study were randomly assigned hypertensive (preoperative systolic blood pressure <180 mmHg and diastolic blood pressure <100 mmHg) C-Mac Videolaryngoscope using intubated | Device: C-Mac Videolaryngoscope<br>* Endotracheal intubation time using the C-Mac Videolaryngoscope<br>|
| Sham Comparator: Non-hypertensive T group<br>Non-hypertensive T group: (Preoperative systolic blood pressure < 140 mmHg and diastolic blood pressure < 100 mmHg) Macintosh laryngoscopy using intubated | Device: Macintosh laryngoscopy<br>* Endotracheal intubation time using the Macintosh laryngoscope<br>|
| Sham Comparator: Non-hypertensive VL group<br>Non-hypertensive VL group: Preoperative systolic blood pressure < 140 mmHg and diastolic blood pressure < 100 mmHg C-Mac Videolaryngoscope using intubated | Device: C-Mac Videolaryngoscope<br>* Endotracheal intubation time using the C-Mac Videolaryngoscope<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Hemodynamic response | Change from baseline noninvasive blood pressure and heart rate | 0-10 minute | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| intubation time | The time elapsed between the passage of the laryngoscopy through the teeth to teeth | 0-120 seconds | 
| Glottic view grade | Using the Cormack Lehane score | During intubation | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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laryngoscopy, videolaryngoscopy, hypertension