Thoracolumbar Burst Fracture Treated With Pedicle Screws: Radiographic Outcomes

Study Overview
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Brief Summary
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The surgical results of thoracolumbar and lumbar burst fracture have been reported to be comparable between patients with and without fusion in a midterm follow-up. There is, however, no report comparing the results of fusion and non-fusion with a long-term follow-up. Therefore, a long term comparative study is still needed to focus on the issues of functional and radiographic outcomes, especially preservation of the motion segment in the long run, to determine whether fusion should be a routine procedure for surgically treated burst fractures of the thoracolumbar and lumbar spines. Therefore, we report herein a long-term comparative study of fusion and non-fusion based on our previous work, with an average 134 months of follow-up.

Official Title
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Thoracolumbar Burst Fracture Treated With Pedicle Screws: Radiographic Analysis of Discs and Vertebral Body Height at Fractured and Adjacent Levels

Conditions
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Burst Fracture

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: neurologically intact spine with a kyphotic angle more than 20o, decreased vertebral body height more than 50% or a canal compromise more than 50%; incomplete neurological deficit with a canal compromise less than 50%; complete neurological deficit; multilevel spinal injury or multiple trauma. Exclusion Criteria: progression of the neurological deficit; a canal compromise still more than 50% in those who showed no improvement of the neurological deficit.

Ages Eligible for Study
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Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| fusion group<br>close reduction with posterior short-segment transpedicular screw fixation with posterior fusion | |
| non-fusion group<br>close reduction with posterior short-segment transpedicular screw fixation without posterior fusion | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Radiologic outcomes | Injured vertebral body height Kyphotic angle Regional segmental motion | postoperative 6 weeks | 
| Radiologic outcomes | Injured vertebral body height Kyphotic angle Regional segmental motion | postoperative 12 weeks | 
| Radiologic outcomes | Injured vertebral body height Kyphotic angle Regional segmental motion | postoperative 6 months | 
| Radiologic outcomes | Injured vertebral body height Kyphotic angle Regional segmental motion | postoperative 12 months | 
| Radiologic outcomes | Injured vertebral body height Kyphotic angle Regional segmental motion | postoperative 24 months | 
| Radiologic outcomes | Injured vertebral body height Kyphotic angle Regional segmental motion | up to postoperative 161 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Functional outcomes | Greenough Low Back Outcome Scale Visual Analogue Scale (VAS) for back pain Neurologic status: Frankel grading system | postoperative 24 months | 
| Functional outcomes | Greenough Low Back Outcome Scale Visual Analogue Scale (VAS) for back pain Neurologic status: Frankel grading system | up to postoperative 161 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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burst fracture, kyphotic angle, surgical outcome