Efficacy of a Resources Activation Treatment on Tic-symptoms

Study Overview
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Brief Summary
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The main purpose of this study is to evaluate the efficacy of a resources activation based treatment programme in children and adolescents aged 8 to 18 years with tic disorders.

Detailed Description
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The main purpose of this study is to evaluate the efficacy of an intervention aimed at the activation of resources for children and adolescents with tic disorders. The activation of resources treatment programme was developed at Department of Child and Adolescent Psychiatry and Psychotherapy at the University of Cologne and is currently evaluated in different studies.

Official Title
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Within Subject Design on the Efficacy of a Resources Activation Treatment Programme in Children and Adolescents With Tics

Conditions
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Tic-Disorder

Intervention / Treatment
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* Behavioral: Resources activation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 8-18 years Diagnosis of chronic motor or vocal Tic (F95.1) or Tourette-Syndrome (F95.2) YGTSS total score F95.2>13, F95.1>9 Tics are the main problems IQ>80 If medication, then has been stable for at least one months in medicated patients No change in medication treatment is planned Ability to participate in weekly outpatient treatment Acceptance of randomization Exclusion Criteria: Diagnosis of Autism Spectrum Disorder or Psychosis Parallel continuous psychotherapy of tics or comorbid

Ages Eligible for Study
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Minimum Age: 8 Years
Maximum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Resources activation<br>At first patients get informed about Tics in general. Through different exercises existing resources and skills are activated and strengthened. Feeling of self-esteem and self-respect are strengthened. Also the emotional awareness is strengthened. Relaxation methods are also introduced. | Behavioral: Resources activation<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Symptom Checklist for Tic-Symptoms (FBB-TIC), parent rating | The FBB-TIC is used to assess Tic-Symptoms according to DSM-IV and ICD-10 rated by parents | Baseline (T0), after 8 weeks (T1), 16weeks (T2), 24weeks (T3) | 
| Change in self-esteem (Harter-Scale-SBB)(self rating) | The Harter-Scale is used to assess self-esteem | T0, after 8 weeks (T1), 24weeks (T3) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Symptom Checklist for Tic-Symptoms (FBB-/SBB-TIC), Teacher-/self-rating | The SBB-TIC is used to assess Tic-Symptoms according to DSM-IV and ICD-10 rated by parents | Baseline (T0), after 8 weeks (T1), 16 weeks (T2), 24weeks (T3) | 
| Change in Symptom Checklist for Tic-Symptoms, clinical rating | The Checklist is used to assess Tic-Symptoms according to DSM-IV and ICD-10 rated by clinicians | Baseline (T0), after 8 weeks (T1), 16weeks (T2), 24weeks (T3) | 
| Change of comorbid ADHD Symptoms (FBB/SBB-ADHD), parent, teacher and self-rating | The Symptom Checklist for Attention Deficit/Hyperactivity Disorder (FBB-/SBB-ADHS) assess all symptom criteria according to DSM IV and ICD-10. | T0, after 8 weeks (T1), 24 weeks (T3) | 
| Change of comorbid OCD Symptoms (ZWIK-E), parent-rating | The ZWIK assess OCD criteria. | T0, after 8 weeks (T1), 24weeks (T3) | 
| Change of comorbid Symptoms (CBCL/TRF/YSR), parent-/teacher-/self-rating | The CBCL, TRF and YSR assess a variation of different criteria. | T0, after 8 weeks (T1), 24weeks (T3) | 
| Change in Tic-Symptoms (YGTSS-TIC), overall score | The YGTSS is used to assess Tic-Symptoms in a semi structured interview with parents and patients | Baseline (T0), after 8 weeks (T1),16weeks (T2), 24weeks (T3) | 
| Change in Tic-Symptoms (observation) | Tic symptoms are observed through video tapes and are rated through clinicians | Between T1 and T3 up to 16 weeks, during each session/week | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Tic-Disorder, Tourette-Disorder, Resources activation