Factors Influencing Nocturnal Symptoms After Refractive Surgery.

Study Overview
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Brief Summary
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By comparing the parameters of the two groups of patients with glare at night after refractive surgery and those without glare at night, the influence of preoperative related parameters on postoperative glare was analyzed.

Official Title
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Effects of Different Pupil Size Under Light and Dark Conditions on Nighttime Symptoms After Refractive Surgery.

Conditions
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Refractive Surgery, Visual Quality

Intervention / Treatment
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* Procedure: refractive surgery


Participation Criteria
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Eligibility Criteria
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Inclusion criteria： Age ≥18 years old； Stable diopter (diopter change less than 0.5D in the past 2 years); Best corrected distance visual acuity (CDVA) of 1.0 or better； Anterior chamber depth (ACD) ≥2.8 mm; Corneal endothelial cell density (ECD) ≥ 2 000 cells/mm. Exclusion criteria: History of ocular trauma or surgery; Suspected keratoconus; Previous history of other ocular diseases such as corneal inflammation or edema, glaucoma, uveitis, retinal detachment, macular degeneration, cataract, amblyopia, etc.; History of severe dry eye； Patients with systemic diseases, such as hyperthyroidism or autoimmune diseases; or severe mental disorders, such as anxiety and depression.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| glare group.<br>Patients subjectively complained about glare and Binoptometer examination showed poor visual quality in dark environments, and they were classified as the glare group. | Procedure: refractive surgery<br>* refractive surgery<br>|
| non-glare group<br>The patients did not complain of glare and the Binoptometer examination showed good visual quality in a dark environment, and they were classified as the non-glare group. | Procedure: refractive surgery<br>* refractive surgery<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes of diopter under bright and dark pupils. | Use OPDScan Ⅲ to measure the parameters of both eyes | Preoperative | 
| Changes of diopter under bright and dark pupils. | Use OPDScan Ⅲ to measure the parameters of both eyes. | Day 7 | 
| Changes of diopter under bright and dark pupils. | Use OPDScan Ⅲ to measure the parameters of both eyes. | Month 1 | 
| Changes of diopter under bright and dark pupils. | Use OPDScan Ⅲ to measure the parameters of both eyes. | Month 3 | 
| Changes of diopter under bright and dark pupils. | Use OPDScan Ⅲ to measure the parameters of both eyes. | Month 6 | 
| objective visual quality. | Measurement of objective visual quality using Binopotometer. | Day 7 | 
| objective visual quality. | Measurement of objective visual quality using Binopotometer and NIDEK Automatic computerized optometry instrument（ARK-1s). | Month 1 | 
| objective visual quality. | Measurement of objective visual quality using Binopotometer. | Month 3 | 
| objective visual quality. | Measurement of objective visual quality using Binopotometer. | Month 6 | 
| subjective visual quality | Using visual quality questionnaire to evaluate patients' subjective visual quality. | Day 7 | 
| subjective visual quality | Using visual quality questionnaire to evaluate patients' subjective visual quality. | Month 1 | 
| subjective visual quality | Using visual quality questionnaire to evaluate patients' subjective visual quality. | Month 3 | 
| subjective visual quality | Using visual quality questionnaire to evaluate patients' subjective visual quality. | Month 6 | 
| ICL Vault | Measuring ICL vault with Pentacam | Day 7 | 
| ICL Vault | Measuring ICL vault with Pentacam | Month 1 | 
| ICL Vault | Measuring ICL vault with Pentacam | Month 3 | 
| ICL Vault | Measuring ICL vault with Pentacam | Month 6 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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refractive surgery, glare, pupil, visual quality, Aberrations