A Study to Explore Prognoses of the Patients With N2 Non-small Cell Lung Cancer

Study Overview
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Brief Summary
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The trial was designed to compare the effectiveness of radical resections of lung cancer plus adjuvant chemotherapies and perioperative chemotherapies in the patients with N2 non-small cell lung cancer

Detailed Description
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The trial is a multi-centre real-world non-interventional observational study. The Chinese patients with N2 non-small cell lung cancer enrolled from 2014 to 2017 who received radical resections of lung cancer and adjuvant chemotherapies will be included in the study and the study data on patient demographic/tumor biological characteristics and clinical treatment will be collected to evaluate compare effectiveness of radical resection of lung cancer plus adjuvant chemotherapies and perioperative chemotherapies after surgeries.

Official Title
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A Multi-centre Real-world Non-interventional Observational Study to Compare Prognoses of the Chinese Patients With N2 Non-small Cell Lung Cancer Who Received Adjuvant Chemotherapies and Perioperative Chemotherapies After Surgeries

Conditions
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Non-small Cell Lung Cancer

Intervention / Treatment
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* Procedure: Surgeries


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients with radical resection of lung cancer enrolled from 2014 to 2019; Pathologically diagnosed patients with non-small cell lung cancer; Patients with age > 18 years old; Patients who did not receive chest surgeries before hospitalization; Patients with N2 lymph nodes (+) after surgeries; Patients who received lymphadenectomy for one group or more groups of lymph nodes; Exclusion Criteria: Patients with second primary tumors or multiple primary tumors;

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Surgeries+adjuvant chemotherapies<br>Patients who received radical resection of lung cancer + adjuvant chemotherapies | Procedure: Surgeries<br>* Surgeries plus adjuvant chemotherapies or perioperative chemotherapies<br>* Other names: Adjuvant chemotherapies or perioperative chemotherapies;|
| Perioperative chemotherapies<br>Patients who received perioperative chemotherapies | Procedure: Surgeries<br>* Surgeries plus adjuvant chemotherapies or perioperative chemotherapies<br>* Other names: Adjuvant chemotherapies or perioperative chemotherapies;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Overall survival | Overall survival | 2014 - 2017 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Disease-free survival | Disease-free survival | 2014 - 2017 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Chinese, real-world evidences, NSCLC, surgeries