Lifestyle Redesign For Schizophrenia

Study Overview
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Brief Summary
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This study aimed to investigate the effects of lifestyle redesign program plus treatment as usual versus treatment as usual on cognition, psychiatric symptoms, quality of life, and occupational engagement for schizophrenia.

Official Title
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The Impact of Lifestyle Redesign Program in Schizophrenia

Conditions
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Schizophrenia, Rehabilitation

Intervention / Treatment
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* Behavioral: lifestyle redesign program


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: diagnosis of schizophrenia, based on the ICD-10 diagnostic criteria for research (World Health Organization, 1992) age from 20 to 65 attending day care center regularly for at least 1 month and taking stable dose of medication Exclusion Criteria: comorbid other mental disorder (e.g. depression, anxiety, ADHD...etc.) comorbid mental retardation lacking the reading and writing skills

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: LRP group<br>The participants in LRP group receive lifestyle redesign program plus treatment as usual. The LRP intervention consisted of one 90-minute session each week for 10 weeks | Behavioral: lifestyle redesign program<br>* In this group, it starts with health education, the participants then change their opinions and experience health activities, and it ends with discussion and sharing their experience.<br>|
| No Intervention: TAU group<br>The participants in TAU group received usual treatment at the same time as LRP group. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change scores of Brief Psychiatric Symptom Rating Scale (BSRS) | The Chinese version of BSRS with 50 items is administered to measure psychiatric symptoms. BSRS items were evaluated on a five-point Likert scale from 0 (not present) to 4 (extremely severe). The total score ranged from 0 to 200, with higher scores reflecting more severe of psychiatric symptoms. | 3 times: 1 to 2 weeks before intervention, 1 to 5 days after intervention and at 1 month after intervention | 
| Change scores of Occupational Self Assessment (OSA) | The OSA with 29 items is administered to measure occupational engagement. | 3 times: 1 to 2 weeks before intervention, 1 to 5 days after intervention and at 1 month after intervention | 
| Change scores of Schizophrenia Quality of Life Scale Revision 4 (SQLS-R4) | The Chinese version of Schizophrenia Quality of Life Scale Revision 4 (SQLS-R4) was administered to measure subjective quality of life. The total scores ranged from 33-165, with higher scores indicating comparatively lower quality of life. | 3 times: 1 to 2 weeks before intervention, 1 to 5 days after intervention and at 1 month after intervention | 
| Change scores of Montreal Cognitive Assessment (MoCA) | The Chinese version of MoCA was administered to measure cognition, with higher scores indicating better cognition. | 3 times: 1 to 2 weeks before intervention, 1 to 5 days after intervention and at 1 month after intervention |