Effects of Pulmonary Rehabilitation on Walking Speed in Patients With COPD or ILD Patients

Study Overview
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Brief Summary
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The aim of this study is to evaluate the effects of a three-week inpatient pulmonary rehabilitation (PR) program on the walking speed in patients with chronic obstructive (COPD) or interstitial lung disease (ILD).

Detailed Description
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At most german traffic light crossings, a walking speed of 1,2m/sec is required to cross the road in time. Patients who are unable to cross the road at this speed, expose themselves to an increased level of stress and possibly the risk of accidents. Thus, they are discouraged from participating in an active social life. An UK study (Nolan et al., Thorax 2018) showed that only 10.7% of the 926 patients with moderate COPD attained a walking speed of 1.2m/sec. As PR plays a key role in the management of chronic lung diseases in order to improve patients´ exercise capacity, the aim of this study was to evaluate the PR effects on the Walking Speed in patients with COPD or ILD. The investigators hypothesize that PR improves the ability to cross the road in the appropriate time.

Official Title
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Effects of a Three-week Inpatient Pulmonary Rehabilitation Program on Walking Speed in Patients With Chronic Obstructive Pulmonary Disease (COPD) or Interstitial Lung Diseases (ILD)

Conditions
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Pulmonary Disease, Chronic Obstructive, Lung Diseases, Interstitial

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Participation in a pulmonary Rehabilitation program (Schön Klinik BGL) Indication: COPD or ILD COPD; FEV1 <50% ILD: FVC <70% written informed consent Exclusion Criteria: non compliance

Ages Eligible for Study
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Minimum Age: 40 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| change of maximum walking speed | assessed during a walk of 11m | Day 1 and Day 21 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change of usual walking Speed | assessed during a walk of 11m by using the individual daily life Walking Speed. | Day 1 and Day 21 | 
| Change in balance | measured by the Leonardo platform | Day 1 and Day 21 | 
| Change in walking speed during a field walk test | measured by the time needed to cross a traffic light (distance: 11m) | Day 1 and Day 21 | 
| Change in tension symptoms during a field walk test | intensity of perceived tension symptoms experienced when crossing a traffic light (VAS scale, ranging from 0 to 10) | Day 1 and Day 21 | 
| Change of exercise capacity | measured by the sit-to-stand test, test duration: 1 minute | Day 1 and Day 21 | 
| Change in maximum leg strength | measured by the microfet, knee Extension | Day 1 and Day 21 | 
| Change in anxiety and Depression symptoms | Anxiety/Depression measured by Hospital Anxiety and Depression Scale (HADS) - a screening questionnaire including seven questions each about Depression and Anxiety; each part ranging from 0 to 21; higher scores indicate higher presence of the respective state | Day 1 and Day 21 | 
| Change of frailty (FFP) | measured by Fried Frailty Phenotype (FFP), including five constructs (weight loss, exhaustion, physical activity, gait speed and weakness); range 0-5, higher scores reflect increased Frailty: A score of 0 is considered as robust, a score of 1-2 is considered as pre-frail, a score lower than 2 reflects Frailty | Day 1 and Day 21 | 
| Change in Quality of life: Chronic Respiratory Disease Questionnaire (CRQ) | assessed by the Chronic Respiratory Disease Questionnaire (CRQ)- a 20-item self-report questionnaire; score 1-7; higher scores indicate a better health-related quality of life | Day 1 and Day 21 | 
| Change in illness perception | assessed by the Illness perception Questionnaire, revised (IPQ-R) - 18 items, score 1-5; higher scores indicate a worse illness perception, except of item 7,9,10,11,12. | Day 1 and Day 21 | 
| Change in COPD-related fears on disease-specific disability | assessed by the German COPD Angst Fragebogen (CAF) - a 20-item self-report questionnaire, rated on a Lickert-scale (score 0-4); highest maximum score: 80 points; higher scores indicate higher anxiety levels. | Day 1 and Day 21 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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walking speed, dyspnoe, stress, anxiety, traffic light