Effect of Rehabilitation Programs Based on Eccentric Exercise of Knee Extensor Muscles in Isotonic and Isokinetic Conditions After Anterior Cruciate Ligament Reconstruction

Study Overview
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Brief Summary
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A randomized clinical trial involving 30 individuals submitted to ACL reconstruction will be conducted. Participants will be randomized into: Group I, submitted to a muscular rehabilitation program based on eccentric isokinetic exercise; and Group II, submitted to a muscular rehabilitation program based on eccentric isotonic exercise. Concomitantly with the muscular rehabilitation protocols, individuals will undergo the same physiotherapeutic protocol with analgesia, edema reduction, range of motion, proprioception and functionality goals. Muscle rehabilitation programs based on eccentric isotonic and isokinetic exercise will begin 45 days after ACL reconstruction. The programs will last six weeks, with training frequency of two sessions per week, separated by a minimum interval of 72 hours.

Official Title
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Effect of Rehabilitation Programs Based on Eccentric Exercise of Knee Extensor Muscles in Isotonic and Isokinetic Conditions After Anterior Cruciate Ligament Reconstruction

Conditions
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Anterior Cruciate Ligament Injury

Intervention / Treatment
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* Other: Isokinetic eccentric exercises
* Other: Isotonic eccentric exercises


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Young adults aged between 18 and 40 years; Recreational athletes; Unilateral ACL injury; Presence of total or partial rupture of unilateral ACL within 90 days after injury; Male subjects; Classification of body mass index up to pre-obese (25.0 - 29.9 kg / m2); Not undergoing any strength training program for the lower limbs in the six months prior to the study. Acceptance of individuals in participating in the procedures proposed by the research. Exclusion Criteria: Recidivism in ligament injuries; Associated ligament and / or meniscal lesions; Previous history (<6 months) of musculoskeletal lesions in the thigh; Patellar tendinopathy; Patellofemoral pain syndrome; Respiratory or cardiovascular conditions that limit the performance of exercises; Users of dietary supplements or anabolic steroids

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 40 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Group 1.<br>The participants randomly allocated to this arm will undergo a muscular rehabilitation program based on the isokinetic eccentric exercise for the extensor muscles of the operated knee. The contralateral non-operated lower limb will be used as control, so it will not undergo any muscular rehabilitation program. | Other: Isokinetic eccentric exercises<br>* The individuals of both groups will be submitted to the same physiotherapeutic protocol with objectives of analgesia, reduction of edema, recovery of range of motion, proprioception and functionality. 45 days after ACL reconstruction, subjects randomly allocated to this arm will be submitted to a muscle rehabilitation program based on isokinetic eccentric exercise lasting six weeks, with training frequency of two sessions per week, separated by a minimum interval of 72 hours.<br>|
| Active Comparator: Group 2.<br>The participants randomly allocated to this arm will undergo a muscular rehabilitation program based on the isotonic eccentric exercise for the extensor muscles of the operated knee. The contralateral non-operated lower limb will be used as control, so it will not undergo any muscular rehabilitation program. | Other: Isotonic eccentric exercises<br>* The individuals of both groups will be submitted to the same physiotherapeutic protocol with objectives of analgesia, reduction of edema, recovery of range of motion, proprioception and functionality. 45 days after ACL reconstruction, subjects randomly allocated to this arm will be submitted to a muscle rehabilitation program based on isotonic eccentric exercise lasting six weeks, with training frequency of two sessions per week, separated by a minimum interval of 72 hours.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The femoral quadriceps muscle mass through nuclear magnetic resonance imaging |  | Change from baseline and six weeks after intervention protocol | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Performance of knee extensors through computerized dynamometry |  | Change from baseline and six weeks after intervention protocol | 
| Functionality of the individuals through Lysholm score |  | Change from baseline and six weeks after intervention protocol | 
| Functionality of the individuals through single and triple hop test |  | Change from baseline and six weeks after intervention protocol |