The Protocol of Enhanced Recovery After Surgery in Colorectal Surgery

Study Overview
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Brief Summary
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The purpose of this study is to determine whether ERAS is safe and can decrease surgical stress, increase functional recovery and reduce complication rate in colorectal surgery.

Detailed Description
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The key factors that keep a patient in hospital after uncomplicated major colorectal surgery include the need for parenteral analgesia(persistent pain), intravenous fluids (persistent gut dysfunction), and bed rest (persistent lack of mobility). These factors often overlap and interact to delay return of function. Obviously, postoperative complications will also prolong the time until recovery and ultimately length of stay. A clinical pathway, called Enhanced Recovery After Surgery(ERAS), to accelerate recovery after colonic resection based on a multimodal programme with optimal pain relief, stress reduction with regional anaesthesia, early enteral nutrition and early mobilisation has demonstrated improvements in physical performance, pulmonary function, body composition and a marked reduction of length of stay. Comparison(s): A total of 500 cases colorectal surgery were randomized to receive ERAS protocol or the traditional protocol, such as mechanical bowl preparation, intravenous fluids until bowl movement recovery and bed rest.

Official Title
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The Protocol of Enhanced Recovery After Surgery in Colorectal Surgery

Conditions
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Colorectal Surgery

Intervention / Treatment
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* Procedure: enhanced recovery after surgery (ERAS) protocol
* Procedure: control


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Colorectal surgery patients Age 20～80 Without comorbidities which will influence prognosis, such as paralysis, spine cataface, or cardiac infarction Exclusion Criteria: Emergency Combined other organ resection Age > 80 Comorbidities which will influence prognosis, such as paralysis, spine cataface, or cardiac infarction

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: A<br>received enhanced recovery after surgery (ERAS) protocol in colorectal surgery | Procedure: enhanced recovery after surgery (ERAS) protocol<br>* An integrated protocol aims to allow patients to recover more quickly from major surgery, avoid medium-term sequelae of conventional postoperative care (e.g. decline in nutritional status and fatigue) and reduce health care costs by reducing hospital stay<br>|
| No Intervention: B<br>normal recovery protocol in colorectal surgery | Procedure: control<br>* normal recovery protocol as usually<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| safety of the ERAS protocol and whether it can decrease surgical stress, increase functional recovery and reduce complication rate in colorectal surgery |  | perioperation and until 30 days after surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Enhanced Recovery After Surgery Protocol(ERAS), Colorectal Surgery