Utilization of High Frequency Ultrasound to Diagnose Chronic Exertional Compartment Syndrome

Study Overview
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Brief Summary
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The purpose of this study is to investigate high frequency ultrasound as a future modality for the diagnosis of chronic exertional compartment syndrome (CECS). The results of the ultrasound will help determine if there are any significant radiologic findings or patterns seen in patients with CECS.

Detailed Description
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The purpose of this study is to investigate high frequency ultrasound as a future modality for the diagnosis of chronic exertional compartment syndrome (CECS). The results of the ultrasound will help determine if there are any significant radiologic findings or patterns seen in patients with CECS. Evaluation of ultrasonographic findings will be dependent on tissue density as measured by hypoechoic versus hyperechoic signal as well as muscle compartment thickness at its largest dimension. A specific aim for this study would be to facilitate future research in order to eliminate the need for painful and invasive diagnostic techniques for CECS.

Official Title
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The Utilization of High Frequency Ultrasound to Diagnose Chronic Exertional Compartment Syndrome: A Pilot Study

Conditions
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Chronic Exertional Compartment Syndrome

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Male or female ages 13 and over Patients with any combination of the following symptoms who would otherwise be evaluated for CECS: Symptoms of leg pain worsened with activity and relieved by rest Pain that is generalized in the anterior or lateral compartments of lower leg Numbness or tingling in the distribution of the superficial peroneal nerve Sensation of slap foot or anterior/lateral compartment weakness Able to exercise for CPT testing: Patients will be asked to go through a standardized warm up on a treadmill with increasing speed and incline settings until symptoms are achieved. They will maintain exercise for a minimum of five minutes or to patient tolerance. Exclusion Criteria: Known vascular disease Neurogenic or radicular symptoms

Ages Eligible for Study
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Minimum Age: 13 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Compartment Pressure Testing<br>Patients who present with symptoms of CECS will be consented and tested per protocol with compartment pressure testing. Concurrently, patients will undergo a high frequency ultrasound to observe any patterns in structure to assist future research in noninvasively diagnosing CECS. Evaluation of ultrasonographic findings will be dependent on tissue density as measured by hypoechoic versus hyperechoic signal as well as muscle compartment thickness at its largest dimension. | |
| Control<br>Control subjects will undergo exercise protocol and ultrasound, but will not have compartment pressure testing completed. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Ultrasound to predict/diagnose CECS | Determine if there are significant radiologic patterns arising on ultrasound imaging to help further future research predict or diagnose CECS using non-invasive methods.Specific aim is to investigate high frequency ultrasound as a future modality for the diagnosis of CECS. The results of the ultrasound will help determine if there are any significant radiologic findings or patterns seen in patients with CECS | 2 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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CECS