linjc16/ctgov huggingface dataset:
Influence of Pain Sensitivity on Lumbar Surgery Outcomes

Study Overview
=================
Brief Summary
-----------------
Pain sensitivity would be associated with surgical outcomes after lumbar spine surgery.

Official Title
-----------------
Influence of Pain Sensitivity on Surgical Outcomes After Lumbar Spine Surgery in Patients With Lumbar Spinal Stenosis

Conditions
-----------------
Lumbar Spinal Stenosis

Intervention / Treatment
-----------------
* Procedure: Surgery for lumbar spinal stenosis


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients aged 40-80 years lumbar spinal stenosis diagnosis and scheduled spine surgery at a tertiary-care teaching institution between June 2012 and April 2013 Exclusion Criteria: a history of major psychiatric disorders (schizophrenia, major depression) or peripheral vascular disease any concurrent serious medical condition that would cause disability or decreased general health status such as sepsis or cancer.

Ages Eligible for Study
-----------------
Minimum Age: 40 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Low pain sensitivity group<br>total Pain Sensitivity Questionnaire score <6.5 | Procedure: Surgery for lumbar spinal stenosis<br>* decompression with or without fusion for lumbar spinal stenosis<br>|
| High pain sensitivity group<br>total pain sensitivity questionnaire score ≥ 6.5 | Procedure: Surgery for lumbar spinal stenosis<br>* decompression with or without fusion for lumbar spinal stenosis<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Oswestry Disability Index |  | up to 12 months after operation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual Analog Pain Scale for back pain |  | up to 12 months after operation | 
| Visual Analog Pain Scale for leg pain |  | up to 12 months after operation | 
| Short-Form 36 | measurement of general health status | up to 12 months after operation |
Nutritional Status Of Under-Six Children: Epidemiology Study (NUTRI-STAT)

Study Overview
=================
Brief Summary
-----------------
This study permit to evaluate the characteristics of children in third year of preschool, during a year, in 16 schools in Thionville (north-eastern France) by the way of the annual medical visit.The aim of the study is to describe the nutritional status of children under-six years of age: underweight, overweight, and obesity considering the sex. .

Detailed Description
-----------------
For several decades the eating behavior has been changing. That note is obviously more true for children, with the arrival of new recipes, not really healthier for all. This study permit to evaluate the characteristics of children in third year of preschool, during a year, in 16 schools in Thionville (north-eastern France) by the way of the annual medical visit. The aim of the research is to estimate the healthy weight corresponding with a height considering the gender.

Conditions
-----------------
Children Behavior About Nutrition

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: third year of preschool in Thionville information of the legal responsibles Exclusion Criteria: opposition of the legal responsible for gathering data

Ages Eligible for Study
-----------------
Minimum Age: 4 Years
Maximum Age: 6 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Female children<br>Female children in third year of preschool in Thionville (north-eastern France) | |
| Male children<br>Male children in third year of preschool in Thionville (north-eastern France) | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Body mass index of children |  | 1 year |
Management and Outcome of Fever in Children in Europe

Study Overview
=================
Brief Summary
-----------------
This is an observational study assessing the management and outcome of children presenting to Emergency Departments (ED) with fever across Europe.

Detailed Description
-----------------
This is an observational study assessing the management and outcome of children presenting to Emergency Departments (ED) with fever across Europe. This study will use large departmental datasets to collect information on at least 50,000 febrile episodes . This study will use large-scale, pseudo-anonymized departmental data, and will not involve consented patient recruitment; nor will it use patient samples. Data included in MOFICHE will be based on that collected as part of routine clinical care. Antibiotic prescription, hospitalisation and number/type of investigations, re-attendance at ED within 5 days of the first hospital presentation will be recorded.

Official Title
-----------------
Personalised Risk Assessment in Febrile Illness to Optimise Real-life Management Across the European Union (PERFORM)

Conditions
-----------------
Antibiotic Prescription

Intervention / Treatment
-----------------
* Other: antibiotic prescription


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: aged 0- 18 years visiting the emergency care. fever measured at ED or history of (measured) fever less than 3 consecutive days prior to presentation at emergency department Exclusion Criteria: -

Ages Eligible for Study
-----------------
Maximum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: antibiotic prescription|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Antibiotic prescription | number of antibiotic prescriptions | one year | 
| hospitalization | number of children requiring admission to hospital | one year | 
| Number of investigations | number of investigations | one year | 
| Number of children re-attending within 5 days of the first hospital presentation. | Number of re-attendance | one year |
Optimized Referral of Knee Patients to the Orthopedic Outpatient Clinic

Study Overview
=================
Brief Summary
-----------------
The purpose of the study is to evaluate an algorithm to screen patients with suspected knee osteoarthritis referred to an orthopedic outpatient clinic by using radiographs and patient-reported symptoms. It will be investigated whether the algorithm is able to identify which patients that are deemed relevant to undergo an orthopedic assessment. This will be evaluated by estimating the sensitivity of the new algorithm compared to with the traditional clinical assessment of the patients.

Detailed Description
-----------------
Further description is provided as eligibility criteria and outcome measures.

Official Title
-----------------
OPtimeret Kirurgisk Visitation af Knæartrose Patienter (OPKVIK)

Conditions
-----------------
Osteoarthritis, Knee

Intervention / Treatment
-----------------
* Other: Orthopedic assessment in the outpatient clinic


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: All patients with a new referral to the orthopedic outpatient clinic with suspected knee osteoarthritis. Exclusion Criteria: Cognitive or language problems that precludes the filling in of the questionnaires Unwillingness to answer the questionnaires Patients with rheumatoid arthritis, neurological diseases or cancer

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patient referred to orthopedic clinic<br>Orthopedic assessment in the outpatient clinic as well as a new algorithm (using patient-reported symptoms and radiographic evaluation) will be applied | Other: Orthopedic assessment in the outpatient clinic<br>* Orthopedic assessment based on clinic evaluation, patient symptoms and radiographic evaluation<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Relevant or Not relevant for orthopedic assessment | Results from the algorithm as well as radiographs and the clinic examination | Through study completion, an average of 1 day (at the initial visit in the orthopedic outpatient clinic) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Knee Injury an Osteoarhtritis Outcome Score (KOOS) | Patient reported symptoms, stiffness, pain, activities of daily living (ADL), function in sport and recreation and knee related quality of life | At baseline | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Referral and Consultation, Orthopedics
FINGER; Finland-Germany Myocardial Infarction Study

Study Overview
=================
Brief Summary
-----------------
The purpose of this observational study is to find characteristics and risk stratification methods for identification of subjects who have increased risk of death, especially sudden cardiac death, after acute myocardial infarction.

Official Title
-----------------
Finnish-German Prospective, Observational Follow-up Study on Risk Assessment of Mortality After Myocardial Infarction

Conditions
-----------------
Acute Myocardial Infarction

Intervention / Treatment
-----------------
* Other: No intervention


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Diagnosis of acute myocardial infarction Consent to the study
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Acute Myocardial Infarction patients<br> | Other: No intervention<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| All cause mortality |  | 10years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Sudden cardiac death |  | 10 years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Death, sudden, All cause mortality
Adapting a Model for Veterans on a Psychiatric Inpatient Unit

Study Overview
=================
Brief Summary
-----------------
This randomized controlled study tests an adapted critical time intervention model for veterans discharged from a psychiatric inpatient unit. It is hypothesized that veterans on the inpatient unit who are assigned to such a community-based team will have shorter lengths of inpatient stay and better mental health. There have been few developments of community-based models of care in the post-deinstitutionalization era of short inpatient stays and the results of the study may inform how inpatient stays can be further reduced.

Official Title
-----------------
Adapting a Critical Time Intervention Model for Veterans on a Psychiatric Inpatient Unit

Conditions
-----------------
Conditions: Serious Mental Illness

Intervention / Treatment
-----------------
* Behavioral: Adapted critical time intervention team


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Admitted to the psychiatric inpatient unit for at least 4 days Willing to participate in community-based treatment Exclusion Criteria: Actively suicidal or homicidal Dementia Drug or alcohol detoxification Physician emergency certificate

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Adapted critical time intervention team<br>Community-based team will help facilitate early inpatient discharge and re-entry into the community. | Behavioral: Adapted critical time intervention team<br> <br> |
| No Intervention: Regular inpatient care<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Length of inpatient stay |  | 1 month follow-up | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mental health functioning |  | 1 month follow up |
Comparison of Telavancin and Vancomycin for Hospital-acquired Pneumonia Due to Methicillin-resistant Staphylococcus Aureus

Study Overview
=================
Brief Summary
-----------------
Study 0019 (NCT00124020) compares the safety and effectiveness of an investigational drug, telavancin, with vancomycin for the treatment of hospital-acquired pneumonia.

Official Title
-----------------
A Phase 3, Randomized, Double-Blind, Parallel-Group, Multinational Trial of Intravenous Telavancin Versus Vancomycin for Treatment of Hospital-Acquired Pneumonia With a Focus on Patients With Infections Due to Methicillin-Resistant Staphylococcus Aureus

Conditions
-----------------
Bacterial Pneumonia

Intervention / Treatment
-----------------
* Drug: Telavancin
* Drug: Vancomycin


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Clinical signs and symptoms consistent with pneumonia acquired after at least 48 hours of continuous stay in an inpatient acute or chronic care facility or acquired within 7 days after being discharged from a hospitalization of greater than or equal to 3 days duration. Exclusion Criteria: Received more than 24 hours of potentially effective systemic (IV, IM or PO) antibiotic therapy for Gram-positive pneumonia immediately prior to randomization.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Telavancin<br> | Drug: Telavancin<br>* Telavancin 10 mg/kg/day IV for up to 21 days<br>* Other names: VIBATIV;|
| Active Comparator: Vancomycin<br> | Drug: Vancomycin<br>* Vancomycin 1 Gm administered every 12 hrs IV for up to 21 days<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Clinical Response | Clinical Response: Categorical (Cured, Failed or Indeterminate) Failure - at least one of the following: Persistence or progression of signs and symptoms of pneumonia that still require antibiotic therapy Termination of study med due to lack of efficacy Death on or after Day 3 attributable to primary infection Cure: Signs and symptoms of pneumonia improved to the point that no further antibiotics for pneumonia were required, and baseline radiographic findings improved or did not progress. Indeterminate: Inability to determine outcome | 7-14 days following end of antibiotic treatment |
Pregnancy Outcomes With a GnRH Antagonist Protocol Versus GnRH-Agonist Protocol in ICSI Cycles

Study Overview
=================
Brief Summary
-----------------
Cycles with GnRH agonist and GnRH antagonist were compared and main outcome measures were the number of oocytes retrieved, injected and fertilized, embryos transferred, and clinical pregnancy and miscarriage rates, were analized.

Detailed Description
-----------------
160 women were equally divided between a GnRH antagonist protocol (Group 1) versus a GnRH agonist protocol (Group 2) in ICSI cycles. The trial was conducted between September 2005 and December 2006. The mean age in both groups was 32 (range 22-40). The main outcome measures were the number of oocytes retrieved, injected and fertilized, embryos transferred, and clinical pregnancy and miscarriage rates.

Official Title
-----------------
Pregnancy Outcomes With a Gonadotropin-Releasing Hormone (GnRH) Antagonist (Cetrorelix) Protocol Versus GnRH-Agonist Protocol in Ovarian Stimulation for ICSI Cycles-a Prospective Study

Conditions
-----------------
Infertility

Intervention / Treatment
-----------------
* Procedure: oocyte retrieval and ICSI procedure


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Infertility couples, absence of endometriosis (confirmed by a previous surgical procedure to investigate infertility), polycystic ovarian syndrome, FSH levels < 12 IU/l, basal levels of estradiol < 20 in the group submitted to the agonist protocol and beginning of stimulation on day 2 in group submitted to antagonist protocol, in the absence of ovarian cysts on the endovaginal ultrasound Exclusion Criteria: use of exogenous LH during stimulation

Ages Eligible for Study
-----------------
Minimum Age: 22 Years
Maximum Age: 40 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: oocyte retrieval and ICSI procedure|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Comparative response to ICSI cycles with GnRH agosnist and cetrotide |  | 16 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Compare number of oocytes retrieved, injected and fertilized, embryos transferred, and clinical pregnancy and miscarriage rates in both groups |  | 16 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
GnRH antagonist, GnRH agonist, ICSI, miscarriage rate, pregnancy outcome
The Role of FDG PET in Radiation Treatment Planning for Head and Neck Cancers

Study Overview
=================
Brief Summary
-----------------
In patients with cancer of the head and neck and rectum, knowing the exact location of the tumor is important for designing the radiation field to ensure delivery of high dose of radiation to the tumor while sparing surrounding normal tissues. A new medical imaging method which is a combination of positron emission tomography (PET) and computed tomography (CT) scan, has shown promise in helping the radiation oncologist in defining the exact location and extent of the tumor in certain cancers such as lung cancers. Therefore the purpose of this study is to determine if these imaging methods can be used in combination with the standard radiation treatment planning procedure to improve the accuracy to targeting your tumor with radiation. In addition the PET-CT scan, similar to the PET scan alone with better resolution, can be used to determine whether the tumor has spread to any part of the body outside of the head and neck sites.

Official Title
-----------------
The Role of FDG PET in Radiation Treatment Planning for Head and Neck Cancers

Conditions
-----------------
Head and Neck Cancer

Intervention / Treatment
-----------------
* Procedure: PET-CT


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria:Patients who are scheduled to receive radiation therapy for head and neck cancer at Stanford. Exclusion Criteria:Non-Stanford patients.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: PET-CT|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
Validation of a Surgical Navigation Algorithm During Knee Replacements in Patients With Knee Osteoarthritis

Study Overview
=================
Brief Summary
-----------------
Ganymed Robotics develops a novel solution of surgical navigation to assist surgeons during knee remplacement surgeries. The aim of this study is to train and validate this novel algorithm.

Detailed Description
-----------------
During knee replacement surgery, per-operative images of the patient's knee will be taken. These images will then be compared with the pre-operative CT-scan of the patient using the novel navigation algorithm. The algorithm will be validated based on its ability to correctly compare both modalities (pre-operative and per-operative images).

Official Title
-----------------
Validation of a Surgical Navigation Algorithm During Knee Replacements in Patients With Knee Osteoarthritis

Conditions
-----------------
Osteoarthritis, Knee

Intervention / Treatment
-----------------
* Other: Images taken during knee replacement surgery


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Adults patients who signed the ICF of the study Patients suffering from knee osteoarthritis requiring a total knee replacement surgery Exclusion Criteria: Patient under the age 18 Patient unable to consent to the study or refusing to participate Patient with history of knee replacement on the knee that will be operated again Patient unable to realize a pre-operative CT-scan Patient not covered by French Health insurance or equivalent.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Images taken during knee replacement surgery|Images taken during knee replacement surgery will be compared to CT-Scan that was performed before surgery|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Validation of navigation algorithm | Comparison between peroperative images and preoperative CT-scan | 12 months |