Natural Dentition, Prosthesis and Antagonist Wear 3D Analysis

Study Overview
=================
Brief Summary
-----------------
Wear resistance is one of the most important physical properties of teeth, and wear resistance of zirconia against artificial acrylic, enamel and composite resin denture teeth has not been clearly established. Implant-supported dental restorations present a higher threshold for occlusion perception when compared to natural teeth, which can occlusal overload mechanisms or lead to wear of rehabilitation materials or the antagonist arch. In clinical conditions, however, many other factors influence the complex interaction between dental enamel and opposing substrates: patient-related factors such as dietary habits, dysfunctional occlusion, masticatory forces, and bruxism contribute to accelerated enamel loss of antagonist teeth.

Detailed Description
-----------------
It will be our intention to perform a prospective study and proof-of-concept to assess wear in natural dentition, Full arch implant supported rehabilitation (FAISR) and opposing arches. Wear according to type of rehabilitation and of opposing arch, technical complications, parafunction and number of placed implants will be assessed. Intra-oral digital acquisition will be performed at pre-defined intervals. Changes over time will be assessed through a previously described digital superimposition methodology volumetric changes determined. Patients will be scanned using an intraoral dental scanner (T0) Patients will be recalled at every 4-months (T1), 8-months (T2) and 12-months (T3) visits for re-scanning and from there every 6-months Scanned images will be compared using a metrology software to determine maximum vertical wear of teeth and root mean square wear.

Official Title
-----------------
Natural Dentition, Prosthesis and Antagonist Wear 3D Analysis

Conditions
-----------------
Wear, Tooth, Dental Prosthesis Complication, Wear, Occlusal

Intervention / Treatment
-----------------
* Device: Monolithic Zirconia
* Device: Hybrid-Acrylic
* Behavioral: Dentate Patients


Participation Criteria
=================
Eligibility Criteria
-----------------
Dentate Group : Inclusion criteria fully dentate (with at least 10 teeth ) and do not have any tooth mobility; at least 12months follow up Exclusion criteria - missing more than 4 teeth, extensive caries, bonded orthodontic brackets Edentulous Group: Inclusion Criteria: Maxilla or Mandible Implant full-mouth implant restoration Monolithic ceramic or hybrid-acrylic restoration at least12 months Follow-up Exclusion Criteria: Heavy bruxists Patients that changed the full arch rehabilitation during the study (ex: framework fracture or lab reparation)

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Dentate Patients<br>Patients with natural dentition - maxilla and mandible | Behavioral: Dentate Patients<br>* Dentate Patients with natural dentition or tooth supported crowns<br>|
| Zirconia<br>Patients that have a full-mouth (maxilla or mandible) dental implant supported rehabilitation restored with monolithic zirconia biomaterial | Device: Monolithic Zirconia<br>* Maxillary or/and mandibular screw retained zirconia monolithic prostheses supported by at least 4 implants<br>|
| Hybrid Acrylic<br>Patients that have a full-mouth (maxilla or mandible) dental implant supported rehabilitation restored with acrylic material (hybrid acrylic) | Device: Hybrid-Acrylic<br>* Maxillary or/and mandibular screw retained hybrid prostheses supported by at least 4 implants;<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Wear of teeth and materials of restorations | Measure in different groups occlusal tooth wear from insertion (baseline) to 4, 8 and 12 months post-insertion Scanned images will be compared using a metrology software to determine maximum vertical wear of teeth and root mean square wear. | at least 12 months follow-up | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Wear of different antagonists | Measure occlusal tooth wear of antagonists from insertion (baseline) to 4, 8 and 12 months post-insertion Scanned images will be compared using a metrology software to determine maximum vertical wear of teeth and root mean square wear. | at least 12 months follow-up | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Tooth wear, Full arch Implant, 3D scanner, Prosthesis, Screw retained, Zirconia, Hybrid Acrylic