Lidocaine Spray for Pain Control in Rib Fractures

Study Overview
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Brief Summary
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In this study, we aimed to compare the analgesic efficacy of lidocaine spray with tramadol hydrochloride and fentanyl citrate in rib fractures.

Detailed Description
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Patients over the age of 18 who came to our emergency department with blunt chest trauma were divided into three groups. Groups was created from patients who were given lidocaine 10% spray (local), i.v. 100 mg of tramadol and i.v. fentanyl 50 mcg. A total of 48 patients, each of whom were 16, were included in the study. Numerical rating scale (NRS) pain scores of the patients at baseline, 15th, 30th and 60th minutes were compared. These scores and the amount of falls at follow-up were analyzed comparatively between the 3 groups.

Official Title
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Comparison of the Analgesic Efficacy of Lidocaine Spray Versus Tramadol and Fentanyl for Pain Control in Rib Fractures: A Prospective, Randomized, Controlled and Open-label Study

Conditions
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Rib Fractures, Analgesia

Intervention / Treatment
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* Drug: Lidocaine topical


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Open conscious Oriented and cooperative Blunt thoracic trauma and rib fracture Numerical rating scale (NRS) was 5 or higher Exclusion Criteria: Patients who refused to participate in the study Detected or suspected pregnancy Known history of allergy or other adverse reaction to the drugs used in the study History of sedative drug use or drug addiction Analgesic use within 6 hours of admission to the emergency department Needed emergency tube thoracostomy or surgical intervention Hemodynamically unstable Open and/or infected wounds in the fracture area

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Interventional Model Description: Pain control in rib fracture
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Lidocaine<br>10% lidocaine spray was applied on the broken rib from a distance of 10 cm, 1-2 puffs. Each puff contains 10 mg of lidocaine. | Drug: Lidocaine topical<br>* Lidocaine spray, which is a quick and easy-to-use topical local anesthetic, will be applied as a puff to the painful area.<br>* Other names: Fentanyl citrate;|
| Active Comparator: Tramadol<br>100 mg of tramadol hydrochloride was placed in 150 cc isotonic saline and given as a 15-minute intravenous infusion. | Drug: Lidocaine topical<br>* Lidocaine spray, which is a quick and easy-to-use topical local anesthetic, will be applied as a puff to the painful area.<br>* Other names: Fentanyl citrate;|
| Active Comparator: Fentanyl<br>50 mcg of fentanyl citrate was given as a 15-minute intravenous infusion in 150 cc isotonic. | Drug: Lidocaine topical<br>* Lidocaine spray, which is a quick and easy-to-use topical local anesthetic, will be applied as a puff to the painful area.<br>* Other names: Fentanyl citrate;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain control | We use Numeric rating scala. | 60th minutes. | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Analgesia, Fentanyl, Lidocaine spray, Rib fracture, Tramadol