Cone Beam CT (CBCT) Arthrogram of the Ankle in Assessement of Osteochondral or Cartilage Lesions

Study Overview
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Brief Summary
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This study aims to compare weight-bearing Cone Beam CT arthrogram and conventional CT arthrogram in assessement of patients with ankle osteo-chondral or cartilage lesions.

Detailed Description
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Weight-bearing Cone Beam CT (CBCT) arthrogram, a technique with less radiation dose than conventional CT, is hypothesized non-inferior to conventional CT arthrogram to diagnose osteo-chondral (OCL) or cartilage lesions of the ankle.

Official Title
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Weight-Bearing Cone Beam CT Arthrogram of the Ankle: a Lower Radiation Dose Technique to Evaluate Osteo-chondral Lesions or Cartilage Lesions: Is it the Future of the arthroCT?

Conditions
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Cartilage Lesion, Osteochondral Lesion

Intervention / Treatment
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* Procedure: ArthroCT scan
* Procedure: CBCT


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients aged ≥ 18 years; Patients require CT arthrogram of the ankle; Affiliated to a social security schema; Informed consent signed by patients. Exclusion Criteria: Pregnant women; Impossibility of injection of intra-articular contrast product; Hypersensitivity reactions to iodinated contrast agent; Patient refusal; Patient under french AME scheme; Patient under guardianship by tutor or curator.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Conventional CT-arthrogram + CBCT arthrogram<br>Conventional CT-arthrogram + CBCT arthrogram (CBCT in the minutes following the conventional CT arthrogram). Routine care (arthroCT) and CBCT of ankle. | Procedure: ArthroCT scan<br>* Conventional CT arthrogram as routine care<br>Procedure: CBCT<br>* Cone Beam CT scan.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Localisation of the lesions | Localisation of cartilage and osteochondral lesions assessed by CT scan | at baseline | 
| Number of the lesions | Number of cartilage and osteochondral lesions assessed by CT scan | at baseline | 
| Size of the lesions | Size of cartilage and osteochondral lesions assessed by CT scan | at baseline | 
| Unstable displaced lesions | Displaced osteochondral fragment in the joint. | at baseline | 
| Unstable non-displaced lesions | Contrast enhanced fluid from the arthrogram surrounding the osteochondral fragment. | at baseline | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Cartilage Lesion, Ankle, Osteochondral Lesion, Osteochondral Defect, Cone Beam arthrogram, CBCT arthrogram, CT arthrogram, Weight bearing CBCT