Prognostic Value of the Selvester QRS Score for Perioperative Myocardial Injury Following Non-cardiac Surgery

Study Overview
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Brief Summary
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The purpose of this study to determine the prognostic value of the Selvester QRS score for perioperative myocardial injury following elective non-cardiac surgery.

Detailed Description
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This study was designed as an investigator-directed, non-commercial, observational, prospective, national, single-center study. The effect of preoperative complex ECG changes on the formation of cardiac damage will be studied. The data of the people participating in the study will be kept entirely confidential. After being informed about the study, all patients giving written informed consent will undergo preoperative evaluation. An ECG and cardiac troponin analysis will be performed to the patients who meet the eligibility. After the surgery will be completed control cardiac troponin and extensive physical examination will be performed.

Official Title
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Prognostic Value of the Selvester QRS Score for Perioperative Myocardial Injury Following Non-cardiac Surgery

Conditions
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Cardiac Ischemia, Cardiac Arrhythmia, Perioperative Injury, Perioperative Complication

Intervention / Treatment
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* Diagnostic Test: Selvester QRS Score with Preoperative ECG


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients who undergoing elective non-cardiac surgery in the operating room ≥18 years old Interpretable preoperative ECG of the patient Preoperative negative high sensitive Cardiac Troponin T ASA I-III class Patients who give the informed consent Exclusion Criteria: A history of myocardial infarction, coronary artery disease, PCI and revascularization A history of chronic renal disease, cerebrovascular incident, stroke ASA class IV Patients who do not give the informed consent Patients who undergoing emergency surgery Patients whose preoperative ECG is not interpretable Minor procedures to be performed outside or inside the operating room

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 90 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Perioperative Myocardial Injury Occured<br>Patients with troponin elevation from the preoperative basal level do not meet the criteria for myocardial infarction according to the fourth universal myocardial infarction guideline, do not describe active anginal complaints, and underwent surgery in the operating room. | Diagnostic Test: Selvester QRS Score with Preoperative ECG<br>* Selvester QRS score will be calculated with the preoperative ECG of the patients.<br>|
| Perioperative Myocardial Injury Not Occured<br>Patients without troponin elevation from the preoperative basal level, do not describe active anginal complaints, and underwent surgery in the operating room. | Diagnostic Test: Selvester QRS Score with Preoperative ECG<br>* Selvester QRS score will be calculated with the preoperative ECG of the patients.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The prediction of perioperative cardiac injury with preoperative Selvester ECG Score | Selvester ECG score is a validated technique for predicting myocardial scar and injury level in patients who undergone PCI. It is aimed to predict and demonstrate perioperative myocardial damage using this algorithm. | Change from Baseline cardiac troponin levels at postoperative 1st hour in PACU | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The prediction of preoperative high-sensitivity troponin and ECG abnormalities on arrhythmia susceptibility. | The prediction of preoperative high-sensitivity troponin and ECG abnormalities on arrhythmia susceptibility by monitoring the cardiac rhythm | Arrhythmia surveillance during peroperative and postoperative 1st hour in PACU | 
| Effect of preoperative cardiac assessment on postoperative cardiac adverse event | Effect of preoperative cardiac assessment on postoperative cardiac adverse event | Cardiac adverse event surveillance during peroperative and postoperative 24 hours | 
| Determination of postoperative intensive care hospitalizations for cardiac reasons | Determination of the reasons of the postoperative intensive care unit hospitalizations for cardiac reasons. | postoperative intensive care hospitalizations for cardiac reasons until postoperative 24 hours | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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myocardial injury, Perioperative injury