The BRAIN App: Building Relationships Using Artificial Intelligence and Nostalgia

Study Overview
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Brief Summary
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This study will involve testing of an Alpha version of an app called Building Relationships using Artificial Intelligence and Nostalgia or BRAIN. The BRAIN App will be the first -ever artificial intelligence infused CST app for PWD. The app has two main goals: (1) to foster positive relationships between the care triad, and (2) to promote QoL while reducing responsive behaviors in PWD. Testing will examine the app's impact on engagement/affect for both PWD and professional Care Partners.

Detailed Description
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A quasi-experimental pretest / posttest design will be used. During a four-week baseline period, researchers will collect data on engagement, quality of life, neuropsychiatric symptoms, and quality of the care-patient relationship. Participants will then use the BRAIN app for four weeks, during which engagement data will be collect. After the intervention period, researchers will collect data again on quality of life, neuropsychiatric symptoms, and quality of the carer-patient relationship.

Official Title
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The BRAIN App: Building Relationships Using Artificial Intelligence and Nostalgia

Conditions
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Dementia, Dementia, Vascular, Alzheimer Disease, Dementia, Mixed

Intervention / Treatment
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* Behavioral: The BRAIN App


Participation Criteria
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Eligibility Criteria
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PWD Inclusion Criteria: diagnosed with dementia (any type) resident in ALF or NH 65+ years old read and speak English exhibit at least one responsive behavior on the NPI-NH or score below maximum score on the DEMQOL PWD Exclusion Criteria: bed-confined completely unable to communicate verbally have serious visual or hearing impairments show signs of rapid decline or over the last six months Staff and Family Member Inclusion Criteria 18+ years old speak and read English Staff and Family Member Exclusion Criteria -n/a

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Interventional Model Description: All participants will receive the intervention
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Treatment<br>BRAIN Intervention | Behavioral: The BRAIN App<br>* The BRAIN App will be the first-ever artificial intelligence enabled cognitive stimulation therapy app, specifically designed for PWD. The goal of the app is to foster positive relationships between the care triad.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Menorah Park Engagement Scale (MPES) | The MPES is an observational scale that measures four types of engagement: Constructive Engagement, Passive Engagement, Distracted Engagement, and Non-Engagement / Apathy The MPES also measures Pleasure, defined as clearly observable smiling or laughing. | Baseline--that is, week 1 thru week 4 | 
| Menorah Park Engagement Scale (MPES) | The MPES is an observational scale that measures four types of engagement: Constructive Engagement, Passive Engagement, Distracted Engagement, and Non-Engagement / Apathy The MPES also measures Pleasure, defined as clearly observable smiling or laughing. | Treatment--that is, week 5 thru week 8 | 
| Engagement for Persons with Dementia Scale (EPWDS) | This scale measures the engagement in 5 domains: affective, visual, verbal, behavioral and social. | Baseline--that is, week 1 thru week 4 | 
| Engagement for Persons with Dementia Scale (EPWDS) | This scale measures the engagement in 5 domains: affective, visual, verbal, behavioral and social. | Treatment--that is, week 5 thru week 8 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Dementia Related Quality of Life (DEMQOL) | The DEMQOL measures quality of life, composed of 28 items. It also has a proxy version | Baseline--that is, week 1 thru week 4 | 
| Dementia Related Quality of Life (DEMQOL) | The DEMQOL measures quality of life, composed of 28 items. It also has a proxy version | Post-Treatment--that is week 5 thru 6 | 
| Neuropsychiatric Inventory--Nursing Home (NPI-NH) | The NPI-NH measures 12 types of neuropsychiatric symptoms, including their severity and frequency. | Baseline--that is, week 1 thru week 4 | 
| Neuropsychiatric Inventory--Nursing Home (NPI-NH) | The NPI-NH measures 12 types of neuropsychiatric symptoms, including their severity and frequency. | Post-Treatment--that is week 5 thru 6 | 
| Quality of Carer-Patient Relationship (QCPR) | This 14-item scale measures warmth and/or absence of conflict or critique on a 5-point scale | Baseline--that is, week 1 thru week 4 | 
| Quality of Carer-Patient Relationship (QCPR) | This 14-item scale measures warmth and/or absence of conflict or critique on a 5-point scale | Post-Treatment--that is week 5 thru 6 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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psychosocial, non-pharmacological