High Flow Nasal Cannula in Comparison to Apneic Oxygenation During Foreign Body Removal by Rigid Bronchoscope

Study Overview
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Brief Summary
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To compare the effect of HFNC with standard apneic oxygenation on patient oxygenation and airway protection during foreign body removal by rigid bronchoscope.

Detailed Description
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This study is a prospective, randomized controlled trial, at Ain Shams University hospitals, Cardiovascular surgery hospital (Thoracic surgery unit), Cairo, Egypt. We will include 64 patients planned for foreign body removal by rigid bronchoscope. All patients will be ASA І with recent FB aspiration in the last 72hrs either by history or documented by radiopaque shadow in chest X ray or CT scan. After achievement of anesthesia and full muscle relaxation ventilation started by open mask technique. Then the patients will be divided into two groups according to the oxygenation technique: Group (A) (32 patients) HFNC (Vapotherm) will be used during the bronchoscopy time flow rate 50 L/min with 100% humidified oxygen and the temperature adjusted to be 38℃ . Group (B) (32 patients) (control group) using the standard apneic oxygenation through the side port of rigid bronchoscope during the procedure

Official Title
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High Flow Nasal Cannula in Comparison to Apneic Oxygenation During Foreign Body Removal by Rigid Bronchoscope

Conditions
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Anesthesia

Intervention / Treatment
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* Device: Vapotherm
* Device: Apneic oxygenation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: We will include 64 patients planned for foreign body removal by rigid bronchoscope. All patients will be ASA І Recent FB aspiration in the last 72hrs either by history or documented by radiopaque shadow in chest X ray or CT scan. Exclusion Criteria: Patients age not more than 40 years old. Body weight less than 40 kg. Critically ill patients. Intubated patients. Inhalation of FB more than 72 hrs.

Ages Eligible for Study
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Minimum Age: 10 Years
Maximum Age: 40 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Group A (High flow nasal cannula group)<br>(Vapotherm) will be used during the bronchoscopy time flow rate 50 L/min with 100% humidified oxygen and the temperature adjusted to be 38℃ | Device: Vapotherm<br>* flow rate 50 L/min with 100% humidified oxygen and the temperature adjusted to be 38℃<br>* Other names: High flow nasal cannula;|
| Active Comparator: Group B (Apeieoc oxygenation group)<br>The standard apneic oxygenation through the side port of rigid bronchoscope during the procedure | Device: Apneic oxygenation<br>* Standard apneic oxygenation through the side port of rigid bronchoscope during the procedure<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Maintain high level of oxygen saturation during the procedure | Monitoring oxygen saturation by pulse oximeter and recording the readings | During the procedure time |