Beijing Friendship Hospital Metabolic Surgery Database

Study Overview
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Brief Summary
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Metabolic surgery, as a recognition treatment option for patients with clinical morbid obesity, is gaining increasing appreciation. In addition to substantial weight loss, emerging studies have highlighted that metabolic surgery can substantially ameliorate obesity-related metabolic diseases, including but not limited to type 2 diabetes mellitus (T2DM), hypertension, dyslipidemia, obstructive sleep apnea-hypopnea syndrome (OSAHS) and polycystic ovary syndrome (PCOS)in severely obese patients. However, further investigations with larger sample size and longer observation time still needed to clarity the efficacy and safety of metabolic surgery in Chinese patients with obesity and encouraging future research in this field.

Official Title
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Beijing Friendship Hospital Metabolic Surgery Clinical Database

Conditions
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Metabolic Surgery

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: be able to receive metabolic surgery (LSG or LRYGB) Exclusion Criteria: can not be able to understand and willing to participate in this registry with signature
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the excess weight loss effect of metabolic surgery after 1year | Percent excess weight loss (%EWL), %EWL=[(initial weight)-(post-op weight)]/[(initial weight)-(ideal weight)] (in which ideal weight is defined by the weight corresponding to a BMI of 25 kg/m2) | 1 year after surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the adverse events rate of metabolic surgery | show the surgical safety by 30 days follow-up according to guideline（such as: bleeding, leak, obstruction, re-operation for complication） | 30 days after surgery | 
| the excess weight loss effect of metabolic surgery with long-time follow-ups | Percent excess weight loss (%EWL), %EWL=[(initial weight)-(post-op weight)]/[(initial weight)-(ideal weight)] (in which ideal weight is defined by the weight corresponding to a BMI of 25 kg/m2) | 3 years | 
| the excess weight loss effect of metabolic surgery with long-time follow-ups | Percent excess weight loss (%EWL), %EWL=[(initial weight)-(post-op weight)]/[(initial weight)-(ideal weight)] (in which ideal weight is defined by the weight corresponding to a BMI of 25 kg/m2) | 5 years | 
| the excess weight loss effect of metabolic surgery with long-time follow-ups | Percent excess weight loss (%EWL), %EWL=[(initial weight)-(post-op weight)]/[(initial weight)-(ideal weight)] (in which ideal weight is defined by the weight corresponding to a BMI of 25 kg/m2) | 10 years | 
| the glycemic control effect of metabolic surgery with long-time follow-ups | the decrease of HbA1c, glucose level, C-peptide and insulin levels | 3 years | 
| the glycemic control effect of metabolic surgery with long-time follow-ups | the decrease of HbA1c, glucose level, C-peptide and insulin levels | 5 years | 
| the glycemic control effect of metabolic surgery with long-time follow-ups | the decrease of HbA1c, glucose level, C-peptide and insulin levels | 10 years | 
| the glycemic control effect of metabolic surgery after 1 year | the decrease of HbA1c, glucose level, C-peptide and insulin levels | 1 year after surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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metabolic surgery, metabolic disease