This Study Performed to Develop a New Technique for Measuring the Intra Abdominal Pressure

Study Overview
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Brief Summary
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The purpose of this study is to evaluate the changes of intraocular pressure due to the increase of intra abdominal pressure.

Detailed Description
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In this prospective study, 40 patients undergoing elective surgery were included. Patients were divided into four groups of 10 patients. The control group (Group C) was not subjected to laparoscopic intervention. Laparoscopic surgery was respectively performed with an intra-abdominal pressure of 9, 12 and 15 mmHg in Groups L (low), M (medium), and H (high pressure). Intraocular pressure was measured binocularly in each patient at three different time (before, during and end of surgery) using a contact tonometer.

Official Title
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The Increase of Intra-abdominal Pressure Can Affect Intra-ocular Pressure.

Conditions
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Abdominal Compartment Syndrome

Intervention / Treatment
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* Other: Intraocular pressure measurement with 9 mmHg insufflation
* Other: Intraocular pressure measurement with 12 mmHg insufflation
* Other: Intraocular pressure measurement with 15 mmHg insufflation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Body mass index (BMI) of 30 kg/m2 or less American Society of Anesthesiologists (ASA) status I-II Exclusion Criteria: Pre-existing eye disease, Cardiovascular or neuromuscular disease, Difficult intubation, The use of any antihypertensive agents.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 55 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: Group C<br>The control group (Group C) was not subjected to laparoscopic intervention | |
| Experimental: Group L<br>Intraocular pressure measurement with 9 mmHg insufflation | Other: Intraocular pressure measurement with 9 mmHg insufflation<br>* Comparison of intraocular pressure levels at different abdominal pressure<br>|
| Experimental: Group M<br>Intraocular pressure measurement with 12 mmHg insufflation | Other: Intraocular pressure measurement with 12 mmHg insufflation<br>* Comparison of intraocular pressure levels at different abdominal pressure<br>|
| Experimental: Group H<br>Intraocular pressure measurement with 15 mmHg insufflation | Other: Intraocular pressure measurement with 15 mmHg insufflation<br>* Comparison of intraocular pressure levels at different abdominal pressure<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| intra-abdominal pressure | Changes in intraabdominal pressure | 1 day after the surgery. | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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laparoscopy,, Intra-abdominal pressure,, intraocular pressure,, abdominal hypertension,, critical care