UW WELL-FIT Exercise Program for Cancer Patients

Study Overview
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Brief Summary
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The purpose of this project is to help to manage the many cancer treatment side effects through cardiovascular and resistance exercise, and education with the goal of using program outcomes to contribute to current research.

Detailed Description
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This study is a single group pre-test post-test design.There are 4 optional measures that will be presented to participants from which they can choose to participate or not. These are presented with check boxes in the consent form. After completion of the University of Waterloo (UW) WELL-FIT program, participants will be given an option to continue with an exercise program; they will be offered the Graduate Program. Following consent of Graduate Program, repeated measures would be taken annually. At the time of consent, they will have the option to have their data used in research. At any point in their involvement of the exercise based programs, they can indicate they no longer want to participate in the program or the data collection. Their medical care or participation in the UW WELL-FIT program will not be affected. Procedures UW WELL-FIT advertisement for Grand River Regional Cancer Centre UW WELL-FIT brochure Referral Form Participants initial consultation and assessment Obtain consent for UW WELL-FIT Obtain Participant Information Completion of FACIT-F survey Metabolism & Body Composition - Information sheet for optional measures Physical Activity Survey- Godin Questionnaire Provide 3-Day food diary and Nutritional Assessment Fitness assessment, exercise programming and data entry: Submaximal cardiovascular cycle ergometer or treadmill graded exercise test Muscular strength using force transducer Body composition: Height, weight and waist girth Bioelectrical Impedance Analysis (BIA) Dual Energy X-ray Absorption (Optional) Range of motion using a goniometer Blood sampling (Optional) Design Individualized exercise program UW WELL-FIT - Commencement of participant in 12 week exercise program (2 x 60 minute classes) Post assessment (repeated pre-test assessments) Pre and post data are entered into database Summary and Feedback Report Graduate Program: participant selects to attend UW WELL-FIT Graduate Program Participants have annual reassessments in the Graduate Program

Official Title
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UW WELL-FIT Exercise Program for Cancer Patients

Conditions
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Cancer

Intervention / Treatment
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* Behavioral: Exercise


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: previously diagnosed with cancer and will currently be receiving some form of treatment (chemotherapy, radiation therapy or hormonal therapy) Exclusion Criteria: Physical / health factors that prohibit exercise or lack of medical clearance from physician
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Cardiovascular and strength training exercise<br>24 sessions ( 12 weeks) exercise | Behavioral: Exercise<br>* Cardiovascular and resistance exercise training<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Maximal Exercise Test | Pre and post maximum workload using an electronic cycle ergometer in Watts | 24 sessions (12 weeks) | 
| Upper and Lower Limb Strength | pre and post strength in upper and lower limb muscles using a linear differential variable transducer (LVDT) measured in Newton.meters | 24 sessions (12 weeks) | 
| Body Mass Index | Pre and post body mass index (kg/m2) | 24 sessions (12 weeks) | 
| Percent Body Fat | Pre and Post percent body fat (units: %) | 24 sessions (12 weeks) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Glucose | measurement of blood glucose in mM | 24 sessions (12 weeks) | 
| Lipids | measurement of total cholesterol, low density lipoprotein,high density lipoprotein ( millimole per liter (mM/L) | 24 sessions (12 weeks) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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body composition, exercise, metabolism, nutrition