Xylitol Chewable Tablets Versus Xylitol Chewing Gum in Geriatric Bedridden Patients

Study Overview
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Brief Summary
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This study will be conducted to evaluate the effectiveness of using dissolving Xylitol chewable tablets versus xylitol chewing gum with bedridden geriatric patients in increasing salivary pH and decreasing bacterial count in both saliva and interdental plaque.

Detailed Description
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This study will be conducted to evaluate the value of using dissolving Xylitol chewable tablets versus xylitol chewing gum with bedridden geriatric patients ,as an alternative to tooth brushing and mouth rinsing, in increasing salivary pH and decreasing bacterial count in both saliva and interdental plaque.plaque and salivary sampling will be taken in certain time ,at baseline T0, then after 5minutes T1, then at 15 days T3. Salivary pH will be measured by using pH meter and streptococcus mutans bacterial count will be calculated through culture in mitis salivarius bacitracin

Official Title
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Effect of Dissolving Xylitol Chewable Tablets Versus Xylitol Chewing Gum on Salivary pH and Bacterial Count in Geriatric Bedridden Patients : Randomized Clinical Trial

Conditions
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Saliva Altered, Plaque

Intervention / Treatment
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* Drug: Listerine ready tabs


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age range above 65 years old Bedridden patients Males or females Concious patients Co-operative patients approving to participate in the trial. Subjects who signed informed consent Exclusion Criteria: Individuals had taken antibiotics during the last four weeks or anticipated doing so during the study Subjects who wore removable prosthesis Patients with systemic diseases that have any oral manifestations History of Smoking Allergy to any of chewing gum or tablets ingredients Evidence of tempromandibular joint disorders Presence of intraoral infections Currently using any mouth rinse

Ages Eligible for Study
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Minimum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Geriatric bedridden patients
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Dissolving xylitol chewable tablets<br>Listerine ready tabs 3 times/day | Drug: Listerine ready tabs<br>* Technically, it's a rectangular-shaped, bilayer-compressed tablet that once chewed, creates just enough liquid to swish around your mouth to get a whole-mouth clean feeling.As manufacture claimed the tablet is easy to use just in three simple steps: chew (to activate), swish (to clean), then swallow as unlike mouthwashes which may contain alcohol and other ingredients not intended for ingestion, Listerine Ready Tabs are alcohol-free and safe to swallow which is highly suitable for bedridden patients.<br>* Other names: Listerine chewable tablets;|
| Active Comparator: Xylitol chewing gum<br>Trident original 3 times/day | Drug: Listerine ready tabs<br>* Technically, it's a rectangular-shaped, bilayer-compressed tablet that once chewed, creates just enough liquid to swish around your mouth to get a whole-mouth clean feeling.As manufacture claimed the tablet is easy to use just in three simple steps: chew (to activate), swish (to clean), then swallow as unlike mouthwashes which may contain alcohol and other ingredients not intended for ingestion, Listerine Ready Tabs are alcohol-free and safe to swallow which is highly suitable for bedridden patients.<br>* Other names: Listerine chewable tablets;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Salivary bacterial count | Streptococcus mutans count in saliva | 15 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Interdental plaque Bacterial count | Mesial and distal Interdental plaquns streptococcus mutans count | 15 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Dental Plaque , salivary pH