Improvement of the Etiological Diagnosis of the Pericarditis

Study Overview
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Brief Summary
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Pericardial syndrome includes pericardites acute pericardial effusion and cardiac tamponade, recurrent pericarditis squeezing chronic pericarditis. The etiologies are very numerous and can be classified as infectious, neoplastic, metabolic or systemic, toxic causes. Diagnosis is difficult, and 80% of etiologies remain classified idiopathic. In their laboratory to improve the diagnosis of this syndrome investigators have developed a strategy of systematic prescription of biological tests by kit. This prescription by 'kit' strategy proved its interest by comparison with an intuitive requirement of biological. In this study investigators want to improve the diagnostic causative of pericarditis by implementing a new diagnostic strategy. This new strategy includes (i) samples additional less invasive for the patient, the swab pharyngeal and nasal, (ii) the addition of at the outset of more effective diagnostic techniques: specific Polymerase Chain Reaction (PCR)

Official Title
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Improvement of the Etiological Diagnosis of the Pericarditis

Conditions
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Infective Pericarditis

Intervention / Treatment
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* Biological: Nasal swab


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patient prescribed with a pericarditis kit for etiological diagnosis of a pericardial syndrome. Adult patient (= or > 18 years old) Patient who freely signed the informed consent form. Patient affiliated to a health insurance regime Exclusion Criteria: Minor patient ( age <18 years) Pregnant, parturient or breastfeeding woman Adult patient incapable or unable to consent Patient deprived of liberty under judgment Person living in a health or social specialised structure Person in vital emergency situation

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Infective Pericarditis<br>In patient prescribed with a pericardite kit for an etiological diagnosis of a pericardial syndrome, an additional nasal swab will be performed in order to perform a specific diagnosis with PCR technique. | Biological: Nasal swab<br>* Nasal swab will be performed in addition to the routine diagnosis visit in order to determine the diagnosis of infective pericardite with a more specific technique: PCR<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Percentage of pericarditis whose etiological diagnosis has been established. |  | 1 day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Identification of the detected emerging pathogens among infectious causesof pericarditis |  | 1 day | 
| Prevalence of the emerging pathogens: assessement of the percentage of emerging pathogens among the studied population |  | 1 day |