PDMS Outcome After Intensive Care, Organdysfunction and Monitoring

Study Overview
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Brief Summary
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The objective of the explorative registry study is to investigate outcome parameters in the routine treatment of patients who are monitored after heart surgery for either short or long-term treatment in the intensive care unit for close monitoring of blood pressure.

Detailed Description
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The close monitoring of patients after cardiac surgery is regarded as standard. However, little is currently known about the influence on patient-related outcome parameters. Recently it has already been shown that intraoperative variability of blood pressure during heart surgery has a postoperative effect on 30-day mortality. The aim of this retrospective study is to investigate the effects of different hemodynamic measurements and management after cardiac surgery on patient-specific outcome parameters.

Official Title
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Patient Data Management System Monitored Outcome After Intensive Care, Organdysfunction and Monitoring

Conditions
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Pleural Effusion, Blood Pressure

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: In-patients of the Charité Universitätsmedizin Berlin at least 18 years old female or male sex cardiosurgical intervention (OPS 5.35 and 5.36) between 01/06 and 12/13. post-operative monitoring of anesthesiological intensive care unit Exclusion Criteria: previous cardiosurgical interventions during the same hospital stay. incomplete documentation

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 100 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Cardiac surgery patients<br>Patients undergoing cardiac surgery at Charité Campus Mitte | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Blood pressure in range | Percentage of RR (Blood Pressure) measurements taken by each patient in the target range as a percentage of the total number of measurements taken by that patient. | Intensive Care stay, an average of 10 days | 
| Blood pressure over range | Percentage of RR measurements of each patient above the target range in relation to the total of all measurements taken by that patient. | Intensive Care stay, an average of 10 days | 
| Blood pressure below range | Percentage of RR measurements taken by each patient below the target range in relation to the total number of measurements taken by that patient. | Intensive Care stay, an average of 10 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Hospital stay | Length of hospital stay | an average of 13 days | 
| ICU stay | Intensive care unit length of stay | an average of 5 days | 
| ICU readmission | Amount of hospital readmissions | an average of 30 days | 
| Renal insufficiency - 1 | Incidence of renal insufficiency | intensive care unit stay, an average of 5 days | 
| Renal insufficiency - 2 | dialysis duration | intensive care unit stay, an average of 5 days | 
| Renal insufficiency - 3 | Urine production | intensive care unit stay, an average of 5 days | 
| Stroke | incidence of strokes | hospital length of stay, an average of 13 days | 
| Drainage loss | Amount of postoperative drainage loss | intensive care unit stay, an average of 5 days | 
| transfusions | number of transfusions needed | hospital length of stay, an average of 13 days | 
| mortality rate-1 | mortality rate after 90 days | 90 days | 
| mortality rate-2 | mortality rate after 180 days | 180 days | 
| Pulse Contour Cardiac Output | data received from Pulse Contour Cardiac Output analyses | intensive care unit stay, an average of 5 days | 
| mortality rate-3 | mortality rate after 5 years | 5 years | 
| mortality rate-4 | mortality rate after 1 year | 1 year | 
| Central venous pressure | central venous pressure on intensive care unit | intensive care unit stay, an average of 5 days | 
| Pleural effusion | In-hospital incidence of pleural effusions postoperatively | hospital length of stay, an average of 13 days | 
| Case cost | Case cost in Euro | hospital length of stay, an average of 13 days |