Bright Light Therapy for Depression Symptoms in Adults With Cystic Fibrosis (CF) and COPD

Study Overview
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Brief Summary
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This is a project that will determine whether the use of daily bright light therapy has an effect on depressive symptoms experienced by adult inpatients with CF and COPD. The purpose of this project is to apply a daily 30-minute BLT intervention to hospitalized adult CF and COPD patients in order to decrease symptoms of depression as measured by depression inventory scoring.

Detailed Description
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This project will occur on a 29-bed pulmonary step-down unit at a 1,600-bed academic medical center. This unit commonly treats patients with CF, COPD, and other pulmonary complications. The unit's patient care staff will be educated on the bright light lamps in order to prevent interruptions and to encourage compliance.

Official Title
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Effect of Bright Light Therapy on Depression Symptoms in Adult Inpatients With Cystic Fibrosis (CF) and Chronic Obstructive Pulmonary Disease (COPD)

Conditions
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Cystic Fibrosis, Depressive Symptoms, Chronic Obstructive Pulmonary Disease

Intervention / Treatment
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* Device: Bright Light Therapy (BLT) Lamp


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Diagnosed with cystic fibrosis or chronic obstructive pulmonary disease (COPD) Adult age 18 or older Admitted to the pulmonary step-down and transplant unit Score greater than zero on pre-intervention Beck's Depression Inventory-II (BDI-II) Exclusion Criteria: Pre-existing ophthalmological conditions or photosensitivity Migraines Receiving high dose steroids for transplant rejection (due to mood altering qualities), Antibiotics that increase light sensitivity Diagnosed with bipolar disorder (light therapy may trigger mania) Admissions anticipated to span less than 48 hours Children are being excluded due to the fact that only adult CF and COPD subjects are admitted to University of Pittsburgh Medical Center (UPMC) Presbyterian hospital

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Intervention Model: Single Group Assignment
Interventional Model Description: This is a non-randomized, single group, pre- and post-intervention project.
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Bright Light Therapy (BLT)<br>The intervention will consist of daily BLT sessions lasting 30 minutes at approximately 10AM (since many CF and COPD patients may not awaken until this time) starting on the day of admission through discharge for a goal of seven consecutive days. The intervention will use a 10,000-lux light box placed approximately 16-24 inches from the patient's face. | Device: Bright Light Therapy (BLT) Lamp<br>* With its built in automatic timer shut-off function, the bedside registered nurse (RN) would not need to return to the room to turn off this lamp after 30 minutes because the lamp will automatically shut off on its own.<br>* Other names: Verilux HappyLight Luxe - UV-Free LED Therapy Lamp by Verilux;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Pre- and Post-intervention Beck's Depression Inventory II Scores (BDI-II) | Change between pre-intervention and post-intervention self-reported answer totals to the 21 scored items on BDI-II (minimum score obtainable=0 (absent symptoms); maximum score obtainable=63 (most severe symptoms). | First at time of admission, second at end of 7 day goal or upon discharge. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of Days Until Completion of Daily Bright Light Therapy (BLT) | The RN will sign a daily log indicating what time therapy was initiated and if therapy was refused. These logs will be collected from patient doors at the end of each week by the principal investigator (PI) in order to measure compliance with completion of therapy on a daily basis. | Daily for duration of intervention period (goal/maximum of 7 days). | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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cystic fibrosis, depression, bright light therapy, adult, copd