Immediate Implant Placement in the Molar Regions

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to look at the bonehealing when a molar has been extracted and immediately replaced by an implant leaving some defects around the implant. The defects are being treated in three different with the hypothesis that the three ways of treatment result in equal bonehealing.

Detailed Description
-----------------
This study is a randomized clinically controlled study with three group of each thirty patients, where the bonehealing after immediate implantplacement in molarregions is being investigated. Totally 90 patients are going to get a molar tooth extracted and immediately replaced with an implant (Brånemark System, Wide Platform). The molar tooth should be in such a condition that is has to be extracted. Extracting a molar leaves a defect which cannot completely be filled out by an implant. The 90 patients are therefore randomised into 3 groups according to how the perimarginal bonedefects around the placed implants are being treated: 1. Bonechips 2. Membrane 3. Bonechips+Membrane. The bonehealing of the defects around the implants are then compared the groups in between. The amount of newly formed bone is being estimated too by digital radiography and subtractionradiography. Furthermore the prognosis for immediate placed implants in molar regions in relation to the method of defectreconstruction one year after crown delivery is also being investigated. All the investigations are conducted with the Ho-hypothesis that there is no difference in the bonehealing the three groups in between.

Official Title
-----------------
Immediate Implant Placement in the Molar Regions

Conditions
-----------------
Periodontitis, Dental Caries, Periapical Periodontitis

Intervention / Treatment
-----------------
* Procedure: Use of a membrane to cover bonedefects around implant
* Device: Use of bonechips to fill up defects around implant
* Procedure: Use of membrane and bonechips to manage defects


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: A molar tooth which has to be extracted Healthy persons with only mild systemic disease with no functional limitation Exclusion Criteria: Pregnant Any disease that is influencing the turnover of bone or oral mucosa

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: Use of a membrane to cover bonedefects around implant|nan|
|Device: Use of bonechips to fill up defects around implant|nan|
|Procedure: Use of membrane and bonechips to manage defects|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Digitial radiography of the implants at placement, 3 month, 6 month, at abutmentoperation, at crownplacement, 3 month after crownplacement and 6 month after crownplacement. |  | see above | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Implant, Immediate placement, Molar tooth