Risk Factors for Community- and Workplace Transmission of COVID-19

Study Overview
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Brief Summary
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The project is an epidemiological observational study based on an electronic questionnaire on risk factors for COVID-19 in the community and healthcare setting.

Detailed Description
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Summary The data collected will identify real-life risk factors for getting the COVID-19 diagnosis. The Oslo University Hospital/University of Oslo web-based solution nettskjema will be used to collect data and consent forms. The impact of knowing the risk factors for COVID-19 is tremendous because it can enable governments to conduct more targeted public health measurements than today to reduce the spread of the virus. Detailed description Research into an ongoing COVID-19 outbreak is difficult because patients are isolated, and supplies of personal protective equipment (PPE) supplies are limited. The risk of transmission to study personal is non-negligible even when PPE is available. A study design based on an electronic questionnaire and consent from delivered from the Oslo University Hospital/University of Oslo, GDPR (General Data Protection Regulation) compliant TSD service has therefore been chosen. The study will be a case-control study based on a combined electronic consent form and questionnaire that the participants will fill in using a smartphone and electronic identification. The groups that will be included are: Hospitalized and non-hospitalized patients/persons with COVID-19 at all stages of the disease and after the disease Hospitalized patients without COVID-19 Healthcare personal or other groups with an increased risk of COVID-19 Healthy volunteers Participants may be followed with repeated questionnaires prospectively. Biological samples Biological samples may hold crucial information about the susceptibility to COVID-19 and for susceptibility to the progression of the disease. It is within the scope of the study to analyze such samples from a limited number of participants which will be asked to provide such samples or hospitalized patients that have surplus material. The material will be analyzed with non-genetic methods most suitable to provide such information.

Official Title
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Risk Factors for Community- and Workplace Transmission of COVID-19

Conditions
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Coronavirus

Intervention / Treatment
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* Behavioral: Observation of behavior and COVID-19 infection will be conducted.


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Norwegian adult Exclusion Criteria: Unable to consent

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Individuals with COVID-19 infection<br>Confirmed by routine laboratory diagnosis. All types of COVID-19 disease from asymptomatic carriers to hospitalized patients can be included. Only subjects >18 years old will be included in the study. | Behavioral: Observation of behavior and COVID-19 infection will be conducted.<br>* No intervention, only prospective observation of behavior will be conducted by a questionnaire.<br>|
| Individuals tested for COVID-19 infection with negative test<br>Confirmed by routine laboratory diagnosis | Behavioral: Observation of behavior and COVID-19 infection will be conducted.<br>* No intervention, only prospective observation of behavior will be conducted by a questionnaire.<br>|
| Healthy individuals<br>Recruitet from the general population | Behavioral: Observation of behavior and COVID-19 infection will be conducted.<br>* No intervention, only prospective observation of behavior will be conducted by a questionnaire.<br>|
| Risk groups for COVID-19 exposure<br>Including, but not limited to healthcare workers. | Behavioral: Observation of behavior and COVID-19 infection will be conducted.<br>* No intervention, only prospective observation of behavior will be conducted by a questionnaire.<br>|
| Patients admitted to hospital<br>Without COVID-19 infection. | Behavioral: Observation of behavior and COVID-19 infection will be conducted.<br>* No intervention, only prospective observation of behavior will be conducted by a questionnaire.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rate of COVID-19 infection | Diagnosed with serology or direct viral detection | 1 year |