Correction of Anisometropic Amblyopia in Children.

Study Overview
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Brief Summary
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Anisometropic amblyopia among children in school age may affects quality of life and educational progress of children.

Detailed Description
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Correction of anisometropic amblyopia depends on type of refractive error and axial length of the eye. In this study, we will asses the types of anisometropia found in children at school age and investigate possible ways for correction of this type of amblyopia.

Official Title
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Correction of Anisometropic Amblyopia in Children at School Age.

Conditions
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Amblyopia, Anisometropic Amblyopia, Anisometropia and Aniseikonia, Refractive Errors

Intervention / Treatment
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* Diagnostic Test: Axial length measurement in millimeter (mm) by optical biometry device
* Diagnostic Test: Autorefractometer to measure the refractive error in both eyes.


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Anisometropic amblyopia. Children at school age ranged from 4 to 12 years old. Exclusion Criteria: Emmetropia children. Children had undergone any intraocular surgeries. Other types of amblyopia.

Ages Eligible for Study
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Minimum Age: 4 Years
Maximum Age: 12 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Axial myopia<br>children have anisometropia due to axial myopia, axial length will be measured by optical biometry device in millimeter (mm). | Diagnostic Test: Axial length measurement in millimeter (mm) by optical biometry device<br>* Axial length measurement of the anisometropic eye and the fellow one in millimeter (mm) by optical biometry device.<br>Diagnostic Test: Autorefractometer to measure the refractive error in both eyes.<br>* Measurement of the refractive state of both eyes for each subject to asses the refractive error in diopter (D).<br>|
| Refractive myopia<br>children have anisometropia due to refractive myopia, axial length will be measured by optical biometry device in mm. | Diagnostic Test: Axial length measurement in millimeter (mm) by optical biometry device<br>* Axial length measurement of the anisometropic eye and the fellow one in millimeter (mm) by optical biometry device.<br>Diagnostic Test: Autorefractometer to measure the refractive error in both eyes.<br>* Measurement of the refractive state of both eyes for each subject to asses the refractive error in diopter (D).<br>|
| Axial hyperopia<br>children have anisometropia due to axial hyperopia, axial length will be measured by optical biometry device in mm. | Diagnostic Test: Axial length measurement in millimeter (mm) by optical biometry device<br>* Axial length measurement of the anisometropic eye and the fellow one in millimeter (mm) by optical biometry device.<br>Diagnostic Test: Autorefractometer to measure the refractive error in both eyes.<br>* Measurement of the refractive state of both eyes for each subject to asses the refractive error in diopter (D).<br>|
| Refractive hyperopia<br>children have anisometropia due to refractive hyperopia, axial length will be measured by optical biometry device in mm. | Diagnostic Test: Axial length measurement in millimeter (mm) by optical biometry device<br>* Axial length measurement of the anisometropic eye and the fellow one in millimeter (mm) by optical biometry device.<br>Diagnostic Test: Autorefractometer to measure the refractive error in both eyes.<br>* Measurement of the refractive state of both eyes for each subject to asses the refractive error in diopter (D).<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Axial length of both eyes. | Measurement of axial length of both eyes in millimeter (mm). | Immediately after optical biometry test for each eye. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of refractive errors in anisometropic amblyopia | Type of refractive error found in anisometropia measured by autorefractometer in diopter (D). | Immediately after autorefractometer test for each eye. | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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amblyopia, axial refractive error, anisometropia