Effect of Salba & Flax on Postprandial Glycemia and Subjective Satiety

Study Overview
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Brief Summary
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The purpose of this study is to determine whether drinks containing Salvia hispanica L (Salba) or Flax lower postprandial blood glucose levels and improve appetite in healthy individuals.

Detailed Description
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Dietary fibre has been implicated in improving many risk factors associated with Type 2 Diabetes and Cardiovascular Disease (CVD). However, on average, Norther Americans consume less than half of the recommended amount set by health agencies. It has been proposed that the health benefits of dietary fibre may be attritbuted to rheological characteristics such as viscosity. Salvia hispanica L (Salba) and Flax are nutritionally similar. The primary objective of this research trial is to study the effects of Salba and Flax on postprandial glycemia and appetite in healthy individuals.

Official Title
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The Effect of Salba (Salvia Hispanica L) Versus Flax on Postprandial Blood Glucose Response and Subjective Appetite in Healthy Individuals

Conditions
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Hyperglycemia, Postprandial

Intervention / Treatment
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* Dietary Supplement: Salba
* Dietary Supplement: Flax
* Dietary Supplement: Control


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: BMI less than 35 kg/m^2 Exclusion Criteria: known history of liver or kidney disease, diabetes, hypertension, stroke, or myocardial infarctions, thyroid disease, gastrointestinal disease, or AIDS subjects using medications or Natural Health Products

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Salba<br>50g glucose 25g ground Salba (Salba Corporation Ltd, Buenos Aires, Argentina) 200ml water | Dietary Supplement: Salba<br> <br> * Other names: Salvia hispanica L;|
| Experimental: Flax<br>50g glucose 31g ground Flax (Bob's Red Mill Natural Raw Whole Flaxseed) 200ml water | Dietary Supplement: Flax<br> <br> |
| Placebo Comparator: Control<br>50g glucose 200ml water | Dietary Supplement: Control<br> <br> * Other names: Glucose;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Postprandial Blood Glucose | At each visit, postprandial blood glucose will be measured via capillary blood samples, at 15, 30, 45, 60, 90, and 120 minutes after intake of test meals | 2 Hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Subjective Satiety | At each visit, subjective satiety (how hungry/full you feel) will be measured via questionnaires, at 15, 30, 45, 60, 90, and 120 minutes after intake of test meals | 2 Hours | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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postprandial glycemia, subjective appetite, Salba, Flax