Effect of Low Level Laser Therapy on Root Resorption During Orthodontic Intrusion of Maxillary Incisors

Study Overview
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Brief Summary
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The present study will be directed to evaluate the effect of low-level laser therapy on root resorption during orthodontic intrusion of upper incisors.

Official Title
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Effect of Low Level Laser Therapy on Root Resorption During Orthodontic Intrusion of Maxillary Incisors: A Comparative Clinical Study

Conditions
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Root Resorption of Maxillary Incisors

Intervention / Treatment
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* Device: gallium aluminum arsenide (Ga-Al-As) semiconductor diode laser (SMARTTM PRO, LASOTRONIX, Poland)
* Other: group B


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients with age range between 12-16 years. Overbite > 40% indicated for maxillary intrusion. Mild to moderate crowding of upper incisors. All permanent teeth erupted (excluding 3rd molars). No previous orthodontic treatment. Good oral hygiene with no previous periodontal surgery Exclusion Criteria: Transverse and/or vertical skeletal dysplasia or craniofacial malformation. Retained primary or missing permanent teeth in the maxillary anterior area, and any kind of tooth/root shape anomaly. Patients with root resorption, impacted canines, or dental anomalies. Poor oral hygiene Present or history of periodontal diseases. Systemic diseases or regular use of medications that could interfere with orthodontic tooth movement. History of trauma affecting the maxillary incisors. Endodontically treated upper anterior teeth.

Ages Eligible for Study
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Minimum Age: 12 Years
Maximum Age: 16 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Experimental group<br>Will includes 9 patients who will receive intrusive arche after leveling and alignment assisted with laser with wavelength 635 nm, 6.5J/cm2,The laser will be applied to 4 points of application for each tooth two labial and two palatal started immediately after first intrusive wire then at days 3,7,14 and then every 15 day until achievement of the study objectives | Device: gallium aluminum arsenide (Ga-Al-As) semiconductor diode laser (SMARTTM PRO, LASOTRONIX, Poland)<br>* The laser will be applied to 4 points of application for each tooth two labial and two palatal started immediately after first intrusive wire then at days 3,7,14 and then every 15 day until achievement of the study objectives<br>|
| Active Comparator: Control group<br>Will includes 9 patients who will receive intrusive arches after leveling and alignment without laser application | Other: group B<br>* Will includes 9 patients who will receive intrusive arches after leveling and alignment without laser application<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| linear amount of root resorption | cone beam computed linear measurements | change in linear root resorption at 4 months | 
| volumetric amount of root resorption | cone beam computed volumetric measurements | change in volumetric root resorption at 4 months |