Exergaming in People With Major Neurocognitive Disorder

Study Overview
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Brief Summary
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This randomized controlled trial explores the efficacy of an 8-week standing exergaming program in people with major neurocognitive disorder (MNCD) residing in long-term care facilities.

Detailed Description
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This randomized controlled trial explores the efficacy of an 8-week standing exergaming program in people with major neurocognitive disorder (MNCD) residing in long-term care facilities. Fifty inpatients with mild to moderate MNCD will be randomly assigned to three times weekly for eight weeks 15 min of exergaming versus watching preferred music videos. The Montréal Cognitive Assessment (MoCA), Short Physical Performance Battery (SPPB), Neuropsychiatric Inventory (NPI), Cornell Scale for Depression in Dementia (CSDD), Dementia Quality of Life (DQoL), Katz activities of daily living (ADL) and Instrumental ADL (IADL) are measured at baseline and post intervention.

Official Title
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The Efficacy of Exergaming in People With Major Neurocognitive Disorder Residing in Long-term Care Facilities: A Randomized Controlled Trial

Conditions
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Randomised Controlled Trial, Major Neurocognitive Disorder, Long-term Care Facility, Physical Activity, Cognitive Impairment

Intervention / Treatment
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* Device: Exergame device


Participation Criteria
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Eligibility Criteria
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Inclusion criteria included: a Diagnostic and Statistical Manual of Mental Disorders (DSM) 5 diagnosis of MNCD (American Psychiatric Association, 2013) aged 65 years or older a score of minimum 10 on the Mini-Mental State Examination (MMSE) residing at least two weeks in the care facility at the time of inclusion being physically capable of doing standing exercises (whether or not with extra support). Possible causes of MNCD were vascular dementia, Alzheimer's disease, mixed dementia, Parkinson's disease or Lewy body disease. Exclusion criteria consisted of: any unstable cardiovascular or other health condition which according to the American College of Sports Medicine Standards might lead to unsafe participation a score lower than 10 on the MMSE a planned transfer to another setting within the following two months.

Ages Eligible for Study
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Minimum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Sequential Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Intervention<br>Dividat senso exergame device | Device: Exergame device<br>* motor-cognitive training<br>* Other names: Dividat senso;|
| Active Comparator: Control<br>Listening to music | Device: Exergame device<br>* motor-cognitive training<br>* Other names: Dividat senso;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| MoCA | Montréal Cognitive Assessment | 2 years | 
| SPPB | Short Physical Performance Battery | 2 years | 
| NPI | Neuropsychiatric Inventory | 2 years | 
| CSDD | Cornell Scale for Depression in Dementia | 2 years | 
| DQOL | Dementia Quality of Life | 2 years | 
| (I)ADL | Activities of daily living | 2 years |