Effect of Cranberry Extract on the Urinary System

Study Overview
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Brief Summary
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In this study, we will try to emphasize the effects of using cranberry tablets, which is an alternative to antibiotic therapy, during uncomplicated urinary tract infections (only urinary tract, bladder and kidney infections did not).

Detailed Description
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This study was Istanbul Kartal Dr. Lütfi Kırdar Training and Research Hospital Emergency Medicine Clinic and Kırklareli Training and Research Hospital Emergency Service and Internal Medicine Polyclinic. Our study; includes patients who applied to the Emergency Department and Internal Medicine outpatient clinic with the complaint of dysuria and had normal WBC, CRP, urea, and creatinine values in their analysis, and leukocyturia was found in the urine test. Two options were offered in the treatment to these patients. Vaccinium Macrocarpon Aiton preparation or fosfomycin was given for seven days. The patients were asked whether their complaints had decreased according to the Lykert-Type verbal scale at the time of admission and on the first, third, and seventh days. When the treatment was finished, leukocytes were checked in the urinalysis. This outcome was compared between the 2 treatment options. We also noted whether nausea.

Official Title
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Effects of Use of Cranberry Extract Instead of Antibiotics During Uncomplicated Urinary Tract Infection

Conditions
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Urinary Tract Disease, Cystitis, Antibiotic Reaction

Intervention / Treatment
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* Drug: Fosfomycin
* Dietary Supplement: Cranberry


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Older than 18 who have urinary tract inflammation who haven't kidney dissease previous Exclusion Criteria: Younger than 18 Who have kidney inflammation Pregnant patients Who have blood test abnormal (WBC, Ure, Creatin, CRP high level)

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| using fosfomycin<br>The patients in this group; have been prescribed fosfomycin for 7 days (3 doses, two days apart). | Drug: Fosfomycin<br>* In this group with urinary tract inflammation; Fosfomycin was prescribed for 7 days (3 doses, 2 days apart). There are 80 patients in total.<br>* Other names: monurol;|
| using cranberry extract<br>The patients in this group; took 7 days (1 tablet each day) of cranberry tablets. | Dietary Supplement: Cranberry<br>* In this group with urinary tract inflammation; 7 days (used every day) cranberry tablet was given. There are 80 patients in total.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Treatment time | After 7 days of treatment, the 2 treatment options were compared with each other. | 7 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Urinary Tract Disease, Cranberry extract, Antibiotic, Cystitis