The Effect Of An Anesthetic Procedure On Post Operative Pain Management In Carpal Tunnel Release

Study Overview
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Brief Summary
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Carpal Tunnel Syndrome patients undergoing carpal tunnel release surgery performed by the PI will receive intra-operative injections of bupivacaine (Marcaine). Two groups of patients will be randomly selected and will receive either 10cc or 20cc of injection. Their post-operative pain scores and usage of post-operative pain medication will be recorded and analyzed.

Detailed Description
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This randomized control trial will be conducted at the USF Department of Orthopaedics at the USF Health Morsani Center after receiving approval from the USF Institutional Review Board. Patients will be evaluated Carpal Tunnel Syndrome and screened as candidates for Carpal Tunnel Release surgery, following the inclusion and exclusion criteria. The Medical Record Number (MRN) will be used to randomly assign into treatment interventions. Group 1 and group 2 will receive 10cc and 20cc of intra-operative intra-carpal tunnel anesthetic injection, respectively. Postoperatively, patients will be prescribed an opioid pain medication in congruence with current standard medical practice. Patients will be contacted at 24-hours, 48-hours, 72-hours, and at 2-week clinic follow-up by research staff and will be evaluated for pain levels through the LIKERT scale and pain management through use of prescribed and supplemental pain medications. All data will be analyzed through SPSS v25.

Official Title
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The Effect Of An Anesthetic Procedure On Post Operative Pain Management In Carpal Tunnel Release

Conditions
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Pain, Postoperative, Carpal Tunnel Syndrome

Intervention / Treatment
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* Drug: 10cc injection of bupivacaine
* Drug: 20cc injection of bupivacaine


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patient must be undergoing carpal tunnel release surgery performed by PI EMG or Ultrasound diagnosed carpal tunnel syndrome Exclusion Criteria: co-musculoskeletal injuries
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 10cc Patients<br>Intervention: Group 1 will receive 10cc of intra-operative intra-carpal tunnel anesthetic injection (bupivacaine/Marcaine). Postoperatively, patients will also be prescribed an opioid pain medication in congruence with current standard medical practice. Patients will be contacted at 24-hours, 48-hours, 72-hours, and at 2-week clinic follow-up by research staff and evaluated for pain levels through the LIKERT scale. | Drug: 10cc injection of bupivacaine<br>* 10cc intra-operative injection of bupivacaine into the carpal tunnel of the operative hand/wrist<br>* Other names: Bupivacaine (Marcaine);|
| Active Comparator: 20cc Patients<br>Intervention: Group 2 will receive 20cc of intra-operative intra-carpal tunnel anesthetic injection (bupivacaine/Marcaine). Postoperatively, patients will also be prescribed an opioid pain medication in congruence with current standard medical practice. Patients will be contacted at 24-hours, 48-hours, 72-hours, and at 2-week clinic follow-up by research staff and evaluated for pain levels through the LIKERT scale. | Drug: 20cc injection of bupivacaine<br>* 20cc intra-operative injection of bupivacaine into the carpal tunnel of the operative hand/wrist<br>* Other names: Bupivacaine (Marcaine);|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Pain Level in various stages of the post-operative period | The investigator will implement a survey using a LIKERT scale regarding post-operative pain levels. | Changes in pain scores at 24 hours, 48 hours, 72 hours, and 2 weeks post-operatively |