linjc16/ctgov huggingface dataset:
Endometrial Injury and Single Embryo Transfer

Study Overview
=================
Brief Summary
-----------------
Endometrial injury increases clinical pregnancy rate in normoresponder patients undergoing long agonist protocol intracytoplasmic sperm injection cycles with single embryo transfer.

Detailed Description
-----------------
Endometrial injury means endometrial biopsy on day 3 of menstrual cycle following down regulation in an IVF patient.

Official Title
-----------------
Endometrial Injury May Increase the Clinical Pregnancy Rate in Normoresponders Underwent Long Agonist Protocol Intracytoplasmic Sperm Injection Cycles With Single Embryo Transfer

Conditions
-----------------
Primary Infertility

Intervention / Treatment
-----------------
* Device: Endometrial injury


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: woman age under 35 years history of primary infertility normoresponder (antral follicle count 5-10 in one ovary in early follicular phase having grade I or II embryos for transfer agree to undergo endometrial biopsy during the COH cycle. All patients were stimulated with luteal phase long protocol. Exclusion Criteria: endocrinopathies (including diabetes mellitus, hyperprolactinemia, Cushing's disease, and congenital adrenal hyperplasia), any systemic disease, collagen disorder, hypercholesterolemia, sickle cell anemia, and a history of neoplasm; -high risk for or history of OHSS using any concurrent medication (e.g., insulin-sensitizing drugs, and GnRH antagonists) patients who did not proceed to follicle retrieval severe male infertility requiring TESA/TESA mullerian tract anomalies a history of endometrial instrumentation or surgery within a month of the study not agree to undergo endometrial biopsy during the COH cycle.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 35 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Endometrial injury<br>The patients in this group will be subjected to endometrial injury procedure in preceding IVF cycle. | Device: Endometrial injury<br>* Endometrial injury with Endometrial Suction Curette (pipelle) will be performed.<br>|
| No Intervention: No endometrial injury<br>The patients in this group will not be subjected to endometrial injury procedure in presiding IVF cycle. The patients will be stimulated with standard IVF protocol. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Clinical Pregnancy Rate |  | up to 6 months | 
| Clinical Pregnancy Rate |  | 4 months |
Collective Accuryn Physiologic Signals and Signatures

Study Overview
=================
Brief Summary
-----------------
The CAPSS Study is a retrospective and prospective, multi-center, single-arm post-market data collection study with an FDA cleared device. Physiologic data measurements will be collected from enrolled subjects using electronic health records and data streams via the Accuryn Monitoring System. Analysis of these data has the potential to be able to acutely guide resuscitation and monitor trends for emerging critical conditions.

Detailed Description
-----------------
The primary objective of the CAPSS Study is to track and analyze changes in physiologic data streams to identify clinical signatures that may enable earlier diagnosis of, and effective intervention in, critical conditions.

Official Title
-----------------
Collective Accuryn Physiologic Signals and Signatures: A Retrospective and Prospective Analysis (CAPSS Study)

Conditions
-----------------
Critical Illness, Acute Kidney Injury, Sepsis, Septic Shock, Abdominal Compartment Syndrome

Intervention / Treatment
-----------------
* Device: Accuryn Monitoring System


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Received Accuryn Monitoring System during hospital stay. Diagnosed with or developed one or more of the targeted conditions while connected to the Accuryn Monitoring System. Exclusion Criteria: 1. In the opinion of the investigator, the patient is unsuitable for the study.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Accuryn Monitoring System<br>Observational only (no intervention). Study Cohort is patients using the Accuryn Monitoring System as a standard-of-care digital urimeter, during their standard course of treatment. | Device: Accuryn Monitoring System<br>* The Accuryn Monitoring System is a novel Foley catheter and monitoring device capable of detecting physiologic changes in vital signs via sensors within the catheter system. These data are captured non-invasively, continuously, and at a high frequency.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Physiologic Changes | Track and analyze changes in physiologic data streams captured using the Accuryn Monitoring System to identify clinical signatures that may enable earlier diagnosis and effective intervention of critical conditions. Potential examples include AKI, sepsis/septic shock, ACS, and optimization of fluid resuscitation. | 30 days |
The Effects of Cognitive Functioning on Gait Rehabilitation

Study Overview
=================
Brief Summary
-----------------
The present study is designed to investigate whether the behavioral and cognitive functioning might predict the outcome of the rehabilitation of gait related abilities in orthopedic patients submitted to elective surgery (total hip arthroplasty). The evaluation of gait related abilities will be performed with specific physiatric tests, while cognitive functioning will be studied by means of an extended neuropsychological battery.

Official Title
-----------------
The Effects of Cognitive and Behavioral Functioning on Gait Rehabilitation in Orthopedic Patients Submitted to Total Hip Arthroplasty

Conditions
-----------------
Total Hip Arthroplasty

Intervention / Treatment
-----------------
* Other: Cognitive and physiatric testing


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age comprised between 50 and 80 years Submission to total hip arthroplasty Admission to the local rehabilitation program Signature of the informed consent Exclusion Criteria: Major medical issues (e.g. neurologial or neurodegenerative diseases) Assumption of psychiatric drugs Pregnancy

Ages Eligible for Study
-----------------
Minimum Age: 50 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Screening
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: THA Patients<br>Orthopedic patients submitted to elective surgery (THA - Total Hip Arthroplasty) | Other: Cognitive and physiatric testing<br>* Neuropsychological test battery and physiatric tests<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Relationship between the cognitive functioning and gait rehabilitation | We will measure the patients' cognitive functioning, investigated by means of a extensive neuropsychological and behavioral battery and the outcome of gait rehabilitation, measured at the enrollment, at 7 days after the enrollment and at 15 days after the enrollment. | The first measures will be taken at the enrollment, at 7 days after the enrollment and at 15 days after the enrollment. |
Rapamycin in Combination With Low-Dose Aracytin in Elderly Acute Myeloid Leukemia Patients

Study Overview
=================
Brief Summary
-----------------
These study is designed to evaluate the tolerability and efficacy of sirolimus (rapamycin) in combination with low-dose aracytin in elderly AML.

Detailed Description
-----------------
Evaluate the tolerability and efficacy of sirolimus (rapamycin) in combination with low-dose aracytin

Official Title
-----------------
Rapamycin in Combination With Low-Dose Aracytin in Elderly Acute Myeloid Leukemia Patients. A Study From the Groupe Ouest Est d'étude Des Leucémies Aiguës Myéloïdes (GOELAMS)

Conditions
-----------------
Acute Myeloid Leukemia

Intervention / Treatment
-----------------
* Drug: rapamycin


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age > 60 y. Informed consent de novo or secondary LAM(CML excluded) not elligible for intensive chemotherapy. Previously untreated Exclusion Criteria: Renal impairment (serum creatinin >2N) Hepatic impairment (TGO ou TGP > 5N), une cholestase (Phosphatases Alcalines or gamma-GT > 5N),bilirubin > 3N Blast crisis CML Acute Promyelocytic Leukemia

Ages Eligible for Study
-----------------
Minimum Age: 60 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: rapamycin|sirolimus|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| response rate |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| tolerability |  |  | 
| bioclinical markers of response |  |  | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
AML, Rapamycin, Elderly, Elderly patients not eligible for intensive chemotherapy
Chinese Women and Mammography Screening

Study Overview
=================
Brief Summary
-----------------
This study examined whether a culturally-tailored video has a greater impact on increasing mammography use in Chinese American women and improving barriers to mammography screening compared to a generic, non-tailored video and a printed fact sheet (control group).

Detailed Description
-----------------
This study examined the efficacy of a culturally-tailored video in increasing mammography use among non-adherent Chinese women (vs. a generic video and control fact sheet). A total of 671 Chinese American women from metropolitan Washington, DC and New York city were enrolled to participate in this study. The majority of participants were recruited from on-site community events and some were recruited through public advertisement and referrals. Participants who completed baseline assessment were randomized to one of the three groups: 1) viewing an 18-minute cultural video, 2) viewing an 18-minute generic video, and 3) reading a fact sheet (control group). Participants were interviewed twice after intervention:1) process evaluation 2-4 weeks post intervention regarding participants' feedback on the materials and repeated key measures of knowledge, cultural views, and health beliefs and 2) outcome evaluation six-months post intervention that assesses actual receipt of mammography use.

Official Title
-----------------
Promoting Adherence to Mammography Use in Chinese Women

Conditions
-----------------
Study Chinese Women Who Have Not Adhered to American Cancer Society Mammography Screening Guideline

Intervention / Treatment
-----------------
* Behavioral: Culturally-tailored video


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Chinese American women had not had a mammography in the past 12 months Chinese American women had no personal history of breast cancer Chinese American women had no mammogram scheduled when enrolled Exclusion Criteria: Non-Chinese Women Regular mammography users

Ages Eligible for Study
-----------------
Minimum Age: 40 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Screening
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Culturally-tailored video<br>The culturally-tailored video was designed to focus on Chinese women's cultural health beliefs and align with Chinese customs, norms, and values, which includes two segments: 1) a soap-opera and 2) recommendation from a Chinese female physician. | Behavioral: Culturally-tailored video<br>* A 18 minute DVD made in Chinese language (i.e. Mandarin and Cantonese)<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Receipt of mammography screening |  | six month post intervention |
Chocolate Balloon Angioplasty Registry

Study Overview
=================
Brief Summary
-----------------
To collect data from real-world use with the Chocolate PTA Balloon Catheter to support the effectiveness of the device for use during percutaneous transluminal angioplasty (PTA) procedures.

Official Title
-----------------
Chocolate Balloon Angioplasty Registry

Conditions
-----------------
Peripheral Arterial Disease

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: >18 years of age Lesion successfully crossed with a guide-wire Reference Vessel Diameter (RVD) within the treatment range of the Chocolate PTA Catheter used at the target lesion appropriate for 1:1 dilatation Patient has given consent for their information to be submitted to this registry Exclusion Criteria: Lesion required stenting as the primary treatment approach Life expectancy <12 months Patient is enrolled in another clinical study that may impact the results of this registry

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Above the Knee<br>Patients treated with the Chocolate balloon for a lesion located above the knee | |
| Below the Knee<br>Patients treated with the Chocolate balloon for a lesion located below the knee | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Achievement of Optimal PTA | Percentage of PTA cases in which <30% diameter stenosis without a flow limiting dissection is achieved without the need for bail-out stenting | average of 2 hours |
McKenzie Exercise Vs Harmonic Technique in Chronic Low Back Pain

Study Overview
=================
Brief Summary
-----------------
The purpose of this study was to investigate the effects of HT compared with McK exercise on pain and disability in patients with LBP.

Official Title
-----------------
Prescription of Two Exercise Therapy Protocols for Treating Chronic Low Back Pain

Conditions
-----------------
Low Back Pain

Intervention / Treatment
-----------------
* Behavioral: McKenzie exercise
* Device: Harmonic technique


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Had persistent back pain at least eight weeks or during the last year subjects must suffer from LBP at least three times and each time lasted more than a week. Exclusion Criteria: Had a history of fracture or surgery in the spine, pelvis and lower extremities through last year History of neuromuscular disease The referral and radicular pain in the lower extremities and neurological or sensory disturbance in the lower extremities Urinary incontinence and pain severity higher that 7 based on visual analogue scale (VAS)

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: McKenzie exercise|First to sixth McKenzie exercises were performed for 5 times/week and 10 treatment sessions totally.|
|Device: Harmonic technique|Lower limb suspension exercise was performed for 5 times/week and 10 treatment sessions totally|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Harmonic technique, Low Back Pain, McKenzie exercise, Pain, Disability
Automated Diagnostic Performance of Smartwatch ECG for Arrhythmia Detection Using the PulseAI Neural Network.

Study Overview
=================
Brief Summary
-----------------
The study is to evaluate the performance of the PulseAI neural network technology at interpreting ECG data recorded using a single-lead Smartwatch (Apple Watch).

Detailed Description
-----------------
Under subject consent, subjects will have a 12-lead ECG immediately followed by a smartwatch ECG. The heart rhythm and ECG interval measurements will be compared between the 12-lead ECG and smartwatch ECG. The arrhythmias will include: Atrial Fibrillation/Flutter Tachycardia Bradycardia Premature Atrial Contractions Premature Ventricular Contractions

Official Title
-----------------
Automated Diagnostic Performance of Smartwatch ECG for Arrhythmia Detection Using the PulseAI Neural Network.

Conditions
-----------------
Arrhythmias, Cardiac

Intervention / Treatment
-----------------
* Device: PulseAI ECG Platform


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patient aged 22 or older, able and willing to participate in the study Patient admitted to hospital for ablation, cardioversion, or cardiac electrophysiological exploration. Patient who has read the information note and has given their consent before any procedure related to the study. Exclusion Criteria: Patient with a pacemaker, implantable defibrillator or cardiac resynchronisation therapy device.

Ages Eligible for Study
-----------------
Minimum Age: 22 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Device: PulseAI ECG Platform|Cloud-based AI-enabled ECG analysis platform|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluate the performance of arrhythmia detection. | Evaluate the performance of arrhythmia detection by the PulseAI neural network applied to ECG data collected via the Smartwatch compared to physicians' interpretation of the 12-lead ECG. | 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluate the performance of the Apple Watch ECG interpretation Software compared to the PulseAI software | Evaluate the performance of the Apple Watch ECG interpretation Software compared to the PulseAI neural network | 12 months | 
| Evalaute the performance of QTc interval measurement | Evaluate the performance of QTc interval measurement by the PulseAI neural network applied to the Smartwatch ECG data compared to physicians' measure of the QTc interval from the 12-lead ECG. | 12 months |
Determination of the Role of Microarray for Prognosis and Prediction to Chemotherapy Sensitivity in Patients With Operable, Locally Advanced and Metastatic Oesophageal Cancer

Study Overview
=================
Brief Summary
-----------------
Knowledge of the impact of gene expression profiling could allow optimisation of chemotherapy regimens for individual patients. It could ensure that patients do not receive a particular form of chemotherapy if it is unlikely to benefit them, and in these circumstances an alternative form of chemotherapy that may prove beneficial could be selected. This information will therefore allow chemotherapy to be tailored to the individual tumour. It may help identify those patients with a poorer prognosis who could be selected for further therapy post surgery or a different treatment strategy at the outset.

Official Title
-----------------
Determination of the Role of Microarray for Prognosis and Prediction to Chemotherapy Sensitivity in Patients With Operable, Locally Advanced and Metastatic Oesophageal Cancer

Conditions
-----------------
Oesophageal Cancer

Intervention / Treatment
-----------------
* Procedure: Endoscopy


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Any patient with histologically proven operable ,locally advanced and metastatic oesophageal or gastric carcinoma. Exclusion Criteria: Second malignancy

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: Endoscopy|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To determine whether specific gene expression profiles are associated with response in oesophago-gastric cancer. |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluation of the association of gene expression profiling and progression free survival and overall survival in patients with oesophago-gastric cancer. |  |  |