Nutritional Follow up After Hospital Discharge for Coronavirus Disease-19

Study Overview
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Brief Summary
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Coronavirus infection is responsible for muscle wasting (sarcopenia), especially during prolonged stays in intensive care. Sarcopenia, in its functional aspect also seems major in patients hospitalized for this infection, in non-ICU unit. Weight loss also appears to be significant, despite a prevalence of overweight and obesity in severe forms. Undernutrition in the obese patient is also possible (undernourished obese and sarcopenia obesity). Anosmia and dysgeusia participate in undernutrition by reducing energy intake. The rehabilitation of these patients requires nutritional support (increased protein intake) associated with progressive retraining to physical activity. An early and proactive management procedure within Coronavirus disease-19 units has been implemented in conjunction with the Transversal Nutrition Unit (TNU). This nutritional care must be continued after discharge. Follow-up by teleconsultation or telephone consultation is put in place after the patient's discharge Primary Objective: Evaluation of nutritional status at the time of admission and discharge and home follow-up in outgoing patients from Coronavirus disease-19 Units Secondary objectives: Description of the evolution of food intake, diversity of food and coverage of needs Evaluation of the muscular strength of the wrist (by grip test in hospital) and on the arms and legs after return home (visual analog scale) Evolution of anosmia and dysgeusia (at the time of hospital admission, at the time of hospital discharge and at home) Level of physical training before infection (IPAQ) Description of the general state of health measured by the performance index - world health organization scale Description of nutritional prescriptions Description of the prevention measures and incidence of Inappropriate Refeeding Syndrome (IRS) Care needs assessments

Official Title
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Nutritional Follow up After Hospital Discharge for Coronavirus Disease-19

Conditions
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Covid-19

Intervention / Treatment
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* Other: nutritional intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Covid positive (RT-PCR) Exclusion Criteria: Unable to answer questions by telephone or teleconsultation directly or through a relative, minors under 16 years of age

Ages Eligible for Study
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Minimum Age: 16 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Covid-19 unit outgoing patients<br>nutritional evaluation and intervention | Other: nutritional intervention<br>* nutritional evaluation and intervention and orientation towards adapted care establishment<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| nutritional evaluation | weight | before Covid, at hospital discharge and between 7 and 45 days after discharge | 
| nutritional evaluation | BMI | before Covid, at at the time of hospital admission, at the time of hospital discharge and between 7 and 45 days after discharge | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| muscle strenght | hand grip | at the time of hospital admission and at the time of hospital discharge | 
| food intake | Caloric account | at the time of hospital admission, at the time of hospital discharge | 
| food intake | self evaluation of food intake | between 7 and 45 days after discharge | 
| muscle strenght | self evaluation of muscle strenght | between 7 and 45 days after discharge | 
| biological nutritional status | albuminemia transthyretinemia electrolytes dosage inflammation status | at the time of hospital admission, at the time of hospital discharge | 
| anosmia | anosmia and agueusia evolution | at the time of hospital admission, at the time of hospital discharge and between 7 and 45 days after discharge | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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nutritional status, malnutrition, diet intervention, sarcopenia, muscle strength