Continuous And Pulsed Ultrasound Treatments On Carpal Tunnel Syndrome

Study Overview
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Brief Summary
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The aim of this placebo-controlled study was to evaluate the effects of pulsed and continuous ultrasound treatments combined with splint therapy on patients with mild and moderate idiopathic carpal tunnel syndrome

Detailed Description
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The study included 36 carpal tunnel syndrome patients who were randomly divided into 3 groups.The first group received 0 W/cm2 placebo ultrasound treatment. second group received 1.0 W/cm2 continuous ultrasound treatment and the third group received 1.0 W/cm2 1:4 pulsed ultrasound treatment 5 days a week for a total of 15 sessions. All patients were also treated with night splints during the treatment. Pretreatment and posttreatment Visual Analogue Scale scores, Symptom Severity Scale scores, Functional Status Scale scores, median nerve motor conduction velocity. and distal latency and sensory conduction velocity of median nerve in the 2nd finger and palm were compared.

Official Title
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The Placebo-Controlled Continuous And Pulsed Ultrasound Treatments on Carpal Tunnel Syndrome : A Randomised Trial

Conditions
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Carpal Tunnel Syndrome

Intervention / Treatment
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* Device: ultrasound
* Device: pulsed ultrasound
* Device: placebo ultrasound


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Mild or moderate idiopathic carpal tunnel syndrome (without thenar atrophy or spontaneous activity on electrophysiological examination of the abductor pollicis brevis (APB) muscle) Exclusion Criteria: Secondary entrapment neuropathies Cervical radiculopathy Systemic diseases with increased risk of the carpal tunnel syndrome Gained surgical relief of the syndrome Treated with ultrasound for the syndrome A history of steroid injections into the carpal tunnel and of physical therapy within the last 3 months Patients with either thenar atrophy or spontaneous activity (fibrillation potentials and positive sharp waves) on electrophysiological examination
Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: ultrasound<br>ultrasound : a frequency of 1 megahertz and with an intensity of 1 W/cm2 | Device: ultrasound<br>* a frequency of 1 megahertz and with an intensity of 1 W/cm2, 5 days a week for a total of 15 sessions<br>|
| Experimental: pulsed ultrasound<br>pulsed ultrasound : a frequency of 1 megahertz and with an intensity of 1 W/cm2 and a pulsed mode duty cycle of 1:4 | Device: pulsed ultrasound<br>* a frequency of 1 megahertz and with an intensity of 1 W/cm2 and a pulsed mode duty cycle of 1:4, 5 days a week for a total of 15 sessions<br>|
| Placebo Comparator: placebo ultrasound<br>placebo ultrasound : same ultrasound device as described above seemed to be working but without delivering any output | Device: placebo ultrasound<br>* same ultrasound device as described above seemed to be working but without delivering any output, 5 days a week for a total of 15 sessions<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change From Baseline in Symptom Severity With Symptom Severity Scale | Post treatment comparison of Symptom Severity Scale between three groups minimum score is 11, maximum score is 55. The clinic of patient worses when the score increases. | three weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change From Baseline in Pain With Visual Analogue Scale | Post treatment comparison of Visual Analogue Scale between three groups min score is 0, maximum score is 10. The clinic of patient worses when the score increases. | Three weeks | 
| Change From Baseline in Functional Status With Functional Status Scale | Post treatment comparison of Functional Status Scale between three groups min score is 8, maximum score is 40. The clinic of patient worses when the score increases. | Three weeks | 
| Changes From Baseline Nervus Medianus Motor Conduction Velocity | Post treatment comparison of Median motor nerve conduction velocity between three groups | Three weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Carpal tunnel syndrome,ultrasound,pulsed ultrasound