Effects of a Transitional Palliative Care Model on Patients With End-stage Renal Failure

Study Overview
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Brief Summary
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Primary aim: To compare the effects of customary care and an interventional Home-based Palliative Renal Program (HBPRP) for ESRF patients To compare the effects of customary care and Home-based Palliative Program (HBPP) for ESRF patients Secondary aim: To explore the lived experiences of patients with ESRF. Hypothesis The transitional renal palliative care model is associated with decreased in unscheduled hospital readmission, reduce length of stay as well as improved quality of life for patients with end-stage renal failure.

Detailed Description
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Objectives Related to the primary aim: Are there differences in healthcare utilization between the ESRF patients in the customary care group and those in the HBPRP group; in the HBPRP group and HBPP group? Are there differences in evaluated health outcomes (functional status, symptom intensity, and satisfaction with care) between the customary care group and the HBPRP group ; in the HBPRP group and HBPP group? Are there differences in perceived health outcomes (quality of life, caregiver burden) between the customary care group and the HBPRP group; in the HBPRP group and HBPP group? Related to the secondary aim: How are the lived experiences compared and contrasted between the customary care group and the HBPRP group; in the HBPRP group and HBPP group?

Official Title
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Effects of a Transitional Palliative Care Model on Patients With ESRF

Conditions
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Palliative Care, Renal Failure, End-stage

Intervention / Treatment
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* Behavioral: Transitional community based palliative care


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patient with chronic kidney disease and diabetic mellitus with Creatinine ≥350 milli mole (uM) or those without diabetic mellitus with Creatinine ≥450 milli mole (uM) who refused renal replacement therapy (RRT); Patient not suitable for long term renal replacement therapy (RRT) after assessment by renal team (e.g. multiple co morbidities, poor functional status and social support) Identified as ESRF patient eligible for palliative care without prior renal replacement therapy Ability to speak Cantonese Living within the hospital service area Ability to be contacted by phone Exclusion Criteria: Discharged to nursing home or other institution Inability to communicate Cognitive impairment, mini mental stage examination (MMSE) < 20 Diagnosed with severe psychiatric disorders such as schizophrenia and bipolar disorder

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Transitional Palliative Care<br>Transitional palliative care include:- telephone follow up for early identification of signs and symptoms home visit for spiritual support | Behavioral: Transitional community based palliative care<br>* transitional palliative care include:- telephone follow up for early identification of signs and symptoms relief of signs and symptoms encountered home visit with spiritual support<br>* Other names: Transitional palliative care;|
| No Intervention: Customary care<br>Customary care receive care :- hospital based medical follow up general nursing assessment and advice | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Healthcare utilization composite - The dates of re-hospitalizations, length of stay, and number of other hospital services used, including clinics and emergency room visits, will be extracted from the hospital administrative systems. |  | for 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluated health outcomes composite (functional status, symptom intensity) - The functional status will be measured by the Palliative Performance Scale (PPS )(appendix 6). | The PPS is a clinical tool commonly used in the local settings. The level of physical performance is rated on a scale of 100 (normal) to 0 (death), measured in 10 % decrement levels. The scale has been validated and the inter-rater reliability between doctors and nurses maintained at .85 with strong kappa values of .97 (Myers J, Gardiner K, Harris K et al., 2010). | 12 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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transitional palliative care, end stage renal failure