Therapeutic Serious Game and Rehabilitation of Stroke Patient

Study Overview
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Brief Summary
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The growing field of new technologies offers new perspectives for neurorehabilitation. Serious games are a promising solution in the rehabilitation of cognitive impairments, and they may be useful in the rehabilitation of unilateral spatial neglect. The investigators developed a rehabilitation program for visual exploration training with a serious game and investigated its efficiency. Six patients with unilateral spatial neglect after a right hemispheric stroke were recruited. Three patients assigned to the experimental group received both serious game training and conventional rehabilitation, and three assigned to the control group received only conventional rehabilitation. The investigators compared the two groups after rehabilitation.

Official Title
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Development of a Therapeutic Serious Game in the Rehabilitation of Stroke Patient

Conditions
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Stroke, Unilateral Spatial Neglect

Intervention / Treatment
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* Behavioral: Serious game rehabilitation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Unilateral spatial neglect syndrome Right cerebral lesion Exclusion Criteria: Epilepsia General mental deterioration Psychiatric disorder No prior history of neurological disease

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Experimental group<br> | Behavioral: Serious game rehabilitation<br>* Three patients received therapeutic serious game rehabilitation in addition to conventional rehabilitation. The serious game was proposed to be played three times per week for four weeks, for a total of 12 sessions, with 15 min per session (= 45 minutes per week).<br>|
| No Intervention: Control group<br> | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bells test | 35 bells are spatially distributed among distractors on sheet of paper (15 on the left side, 5 on the center and 15 on the right side). Subjects have to cancel as many bells as possible. The number of omissions on the left and on the right side is recorded. | up to 4 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bisection of lines | 2 lines of 200 millimeters are presented on a sheet of paper. Subjects have to mark the middle of the lines. The deviation from the objective middle is measured in millimeter. | up to 4 weeks | 
| Ogden scene copying | Copying of the 'Ogden scene' required participants to copy a scene that consisted of 2 trees, a fence and a house (shown from left to right side of the page). Each stroke in the scene to be copied was counted as a point; each omitted stroke was scored as one error, and each distorted or misplaced stroke was scored as one-half of an error (/4). | up to 4 weeks | 
| Reading task | A text of 116 words is presented with 61 words on the left side and 55 on the right side. Subjects have to read this text. Number of omissions on the left and on the right side is recorded. | up to 4 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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serious game, stroke, unilateral spatial neglect, rehabilitation