Effects of a Time Restricted Eating Protocol on Resistance Training Men

Study Overview
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Brief Summary
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The study sought to investigate the effects of 16/8 time restricted eating (TRE) with windows of 16 hours of fasting and 8 hours of eating on on body composition, muscle strength, and metabolic factors during resistance training in healthy resistance trained males

Detailed Description
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Thirty-four resistance-trained males were randomly assigned to a TRE group or to a control normal pattern group (ND) with a traditional meal pattern. The TRE group consumed 100% of the daily energy needs in an 8-hour time window: from 1PM (post meridiem) to 8:00 PM whilst the ND group consumed 100% of their daily energy needs in 3 meals between 8:00 AM (ante meridiem) and 8:00 PM. During the experimental period, training loads were similar and standardize in the two groups. partecipants were tested before and after 8 weeks of the intervention. Body composition , basal metabolism, performances indexes and blood parameters were measured. After the completition of the first two months of study, subjects were ask to volunteer to continue the intervention for 10 extra months. A total of twenty subjects from, 10 from each group (TRE or ND) continued and completed the second part of the study.

Official Title
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Effects of Time-restricted Eating and Resistance Training on Body Composition, Inflammatory Markers and Cardiometabolic Risk Factors

Conditions
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Fasting, Healthy

Intervention / Treatment
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* Other: Time restricted eating
* Other: Normal Diet


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: continuously engaged in resistance training for at least 5 years at least 3 years experience in split training routines male Exclusion Criteria: adherence to special diets use of nutritional supplements (except a daily multivitamin-mineral and/or protein supplement) use of steroids use of medications

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 40 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: It is a single blind, parallel arms study
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Time restricted eating (TRE) - two month<br>partecipants underwent 2 months of a TRE protocol, during which they consumed 100% of the daily energy needs in an 8-hour time window: from 1:00 PM to 8:00 PM. Body composition, muscle strength and blood parameters were measured before and after the diet intervention. | Other: Time restricted eating<br>* TRE subjects consumed 100 % of their energy needs divided into three meals consumed at 1 p.m., 4 p.m. and 8 p.m., and fasted for the remaining 16 h per 24-h period.<br>|
| Active Comparator: Normal Diet (ND) - two month<br>partecipants underwent 2 months of a regular diet schedule and consumed 100% of the daily energy needs in 3 meals between 8:00 AM and 8:00 PM. Body composition, muscle strength and blood parameters were measured before and after the diet intervention. | Other: Normal Diet<br>* ND group ingested their caloric intake as three meals consumed at 8 a.m., 1 p.m. and 8 p.m.<br>|
| Experimental: Time restricted eating (TRE) - twelve month<br>partecipants underwent 12 months of a TRE protocol, during which they consumed 100% of the daily energy needs in an 8-hour time window: from 1:00 PM to 8:00 PM. Body composition, muscle strength and blood parameters were measured before and after the diet intervention. | Other: Time restricted eating<br>* TRE subjects consumed 100 % of their energy needs divided into three meals consumed at 1 p.m., 4 p.m. and 8 p.m., and fasted for the remaining 16 h per 24-h period.<br>|
| Active Comparator: Normal Diet (ND) - twelve month<br>partecipants underwent 12 months of a regular diet schedule and consumed 100% of the daily energy needs in 3 meals between 8:00 AM and 8:00 PM. Body composition, muscle strength and blood parameters were measured before and after the diet intervention. | Other: Normal Diet<br>* ND group ingested their caloric intake as three meals consumed at 8 a.m., 1 p.m. and 8 p.m.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Fat Mass | fat mass measured dual energy X-ray absorptiometry (DXA) | change from baseline to up to 2 months | 
| Fat Free Mass | fat free mass measured dual energy X-ray absorptiometry (DXA) | change from baseline to up to 2 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Fat Mass | fat mass measured dual energy X-ray absorptiometry (DXA) | change from baseline to up to 12 months | 
| Fat Free Mass | fat free mass measured dual energy X-ray absorptiometry (DXA) | change from baseline to up to 12 months | 
| total cholesterol | total cholesterol as milligram per deciliter | change from baseline to up to 2 months | 
| total cholesterol | total cholesterol as milligram per deciliter | change from baseline to up to 12 months | 
| glucose | glucose as milligram per deciliter | change from baseline to up to 2 months | 
| glucose | glucose as milligram per deciliter | change from baseline to up to 12 months | 
| Leg muscle strength | Leg muscle strength measured via via 1-RM test | change from baseline to up to 2 months | 
| Leg muscle strength | Leg muscle strength measured via via 1-RM test | change from baseline to up to 12 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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fasting, time restricted eating, resistance training, body composition, inflammation