Effect of Standardized Nutrient Management on Clinical Outcomes of Hematopoientic Stem Cell Transportation Patients

Study Overview
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Brief Summary
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To analysis a standardized stepped nutritional treatment process for patients with hematopoietic stem cell transportation, including nutritional risk screening and assessment, standardized nutritional treatment implementation, therapeutic effect follow-up and monitoring, family nutritional treatment follow-up, etc

Detailed Description
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Standardized nutrition therapy for patients with hematopoietic stem cell transportation should follow the principle of sequential treatment of nutrition, which is the preferred scheme with individualized dietary advice or oral nutritional supplement, if their energy intake will not reach 60% of the goal level during the transplanting, then supplementary parenteral nutrition or total parenteral nutrition is needed. The standardized nutrition therapy aims to improve quality of life and long-term survival rate of patients, reduce the complications and social burden of disease.

Official Title
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Effect of Standardized Nutrient Management on Clinical Outcomes of Hematopoientic Stem Cell Transportation Patients--a Cross-sectional Study

Conditions
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Nutrition Related Cancer

Intervention / Treatment
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* Dietary Supplement: dietary advice, oral nutritional supplement, supplementary parenteral nutrition or total parenteral nutrition


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: • Patients treated with HSCT Exclusion Criteria: nothing

Ages Eligible for Study
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Minimum Age: 10 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| test group<br>all the patients treated with HSCT are with nutrition risk, so they will be all included to accept nutrition therapy. | Dietary Supplement: dietary advice, oral nutritional supplement, supplementary parenteral nutrition or total parenteral nutrition<br>* All HSCT(hematopoietic stem cell transplantation) patients should be accepted dietary advice or oral nutritional supplement, if their energy intake will not reach 60% of the goal level during the transplanting, then supplementary parenteral nutrition or total parenteral nutrition.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Improvement of nutritional status | We collect the body composition and grip strength of every HSCTpatients. Body composition include the muscle and fat contents.They are all measured as kilogram. (kg). Specific nutritional guidelines will be provided based on body composition results | 4 months | 
| Improvement of quality of life | We asked each patient to complete the quality of life scale for every HSCTpatient. There are 32 questions in the scale, and each question has 4-7 options. The higher the score, the heavier it is.We will decide whether to give psychological intervention based on the score. | 4 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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HSCT; Nutrtion