Efficacy and Safety of Zingiber Officinale Roscoe Extract on Body Fat

Study Overview
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Brief Summary
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This study was conducted to investigate the effects of daily supplementation of Zingiber officinale Roscoe extract on body fat.

Detailed Description
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This study was a 12 weeks, randomized, double-blind, placebo-controlled human trial. Forty subjects were randomly divided into Zingiber officinale Roscoe extract 200 mg or placebo group. The investigators measured Body Fat Mass, Percent Body Fat, Fat Free Mass, weight, and body mass index.

Official Title
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A 12-week, Randomized, Double-blind, Placebo-controlled Human Trial to Evaluate the Efficacy and Safety of Zingiber Officinale Roscoe Extract on Body Fat

Conditions
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Obesity

Intervention / Treatment
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* Dietary Supplement: Zingiber officinale Roscoe extract 200 mg
* Dietary Supplement: Placebo


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: age between 19 and 65 years, BMI 25 29.9 kg/m2 subjects giving written informed consent Exclusion Criteria: Significant variation in weight(more 10%) in the past 3 months Cardiovascular disease, e.g. arrhythmia, heart failure, myocardial infarction, and patient with pacemaker History of disease that could interfere with the test products or impede their absorption, such as gastrointestinal disease or gastrointestinal surgery Participation in any other clinical trials within past 2 months Laboratory test, medical or psychological conditions deemed by the investigators to interfere with successful participation in the study Pregnancy or breast feeding etc,.

Ages Eligible for Study
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Minimum Age: 19 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Zingiber officinale Roscoe extract 200 mg<br>2 cap/day, 800 mg/cap for 12 weeks | Dietary Supplement: Zingiber officinale Roscoe extract 200 mg<br>* 2 cap/day, 800 mg/cap for 12 weeks<br>|
| Placebo Comparator: Placebo<br>Placebo for 12 weeks | Dietary Supplement: Placebo<br>* Placebo for 12 weeks<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes of body fat mass | Body fat mass was measured in study baseline and 12 week | Baseline and 12 week | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes of percent body fat | Percent body fat was measured in study baseline and 12 week | Baseline and 12 week | 
| Changes of fat free mass | Fat Free Mass was measured in study baseline and 12 week | Baseline and 12 week | 
| Changes of weight | Weight was measured in study baseline and 12 week | Baseline and 12 week | 
| Changes of body mass index | Body mass index was measured in study baseline and 12 week | Baseline and 12 week |