Effect of Critical Patients Mobilization on Respiratory and Peripheral Muscle Strength and Functional Capacity.

Study Overview
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Brief Summary
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To analyze changes on respiratory muscle strength, peripheral and functional capacity of critically ill patients with clinical and surgical etiology, breathing spontaneously and bedridden, within 48 hours of admission to the intensive care unit (ICU) and if there are correlations among these variables. This is an observational study. Respiratory muscle strength will be assessed through the maximum inspiratory pressure (MIP) and maximal expiratory pressure (MEP) and peripheral muscle strength, by the Medical Research Council score (MRC) and hand grip test and functional capacity through the Functional Independence Measure (FIM) and Physical Function ICU Test Score (PFIT-s) in the period between 24h and 48h of hospitalization in the adult ICU. For descriptive purposes, the sample will be stratified according to clinical and surgical characteristics. Correlations will be determined using the Pearson test, with significance level of p <0.05.

Official Title
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Effect of Spontaneously Breathing Critical Patients Mobilization on Respiratory and Peripheral Muscle Strength and Functional Capacity.

Conditions
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Intensive Care Unit Syndrome, Muscle Weakness

Intervention / Treatment
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* Procedure: Early ambulation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Breathing spontaneously Length of stay in ICU greater than 24 hours Adherence to study Exclusion Criteria: Patients with poor prognosis or palliation; Preexisting neuromuscular diseases; Immobility or restriction to bed prior to admission; Nonunions and amputations; Osteomioarticular, cognitive or neurological impairment; Non-cooperation; Specific contraindications to the application of evaluation methods; Hemodynamic or respiratory instability within 48 hours of ICU admission preventing evaluation muscle strength and functional capacity.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Mobilization<br> | Procedure: Early ambulation<br>* Procedure to accelerate the ability of a patient to walk or move about by reducing the time to ambulation. It is characterized by a shorter period of hospitalization or recumbency than is normally practiced.<br>* Other names: Early mobilization;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Respiratory muscle strength | Respiratory muscle strength will be assessed through the maximum inspiratory pressure (MIP) and maximal expiratory pressure (MEP). | 48 hours | 
| Peripheral muscle strength | The peripheral muscle strength will be assessed through the Medical Research Council score (MRC) and hand grip test. | 48 hours | 
| Functional capacity | The functional capacity will be assessed through the Functional Independence Measure (FIM) and Physical Function ICU Test Score (PFIT-s). | 48 hours |