linjc16/ctgov huggingface dataset:
Prognostic Value of the 6-minute Stepper Test in Non-small Cell Lung Cancer Surgery

Study Overview
=================
Brief Summary
-----------------
The objective of this study is to evaluate the performances of the Six-Minute Stepper Test (6MST) and Sit To Stand test (STST) to predict post-operative complications after minimally invasive lung cancer resection.

Official Title
-----------------
Prognostic Value of the 6-minute Stepper Test in Non-small Cell Lung Cancer Surgery

Conditions
-----------------
Lung Neoplasm Malignant, Resectable Lung Non-Small Cell Carcinoma

Intervention / Treatment
-----------------
* Diagnostic Test: Six minutes stepper test (6MST)
* Diagnostic Test: Sit to stand test (STST)


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age >18 Non-small cell lung cancer stage I to II, justifying major resection by VATS or RATS (segmentectomy, lobectomy, pneumonectomy), with or without histological confirmation Exclusion Criteria: Partial or total amputation localized to the lower limb; Weight greater than 100 kg; Orthopedic, vascular or neurological disorders leading to the incapacity of realize the 6MST; Patient under tutorship or curatorship; Pregnant woman. Surgery canceled

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: Six minutes stepper test (6MST)|The 6MST is done using a stepper (Stepper essential, Decathlon(TM), France), with a walking height of 20 cm, placed in front of a wall or parallel bars, so patients can hold on if necessary. Patients are instructed to make the maximum number of steps possible in 6 minutes, and are given a time check at one minute intervals.|
|Diagnostic Test: Sit to stand test (STST)|The STST is done using a chair measuring 47 cm in height. The patient are instructed to sit in the chair and then to do the maximum number of lifts possible from the chair, in 1 minute, with arms folded and without leaning against the chair.|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| occurrence of a post-operative complication grade ≥ 2 on the Clavien-Dindo scale within three months after surgery |  | 90 days | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
lung resection, low technology, six minutes stepper test, sit to stand test, physiotherapy, lung surgery, post-operative complications
COVID-19 Tests: Nasopharyngeal Swab vs Saliva Collected With Salivette® Cortisol for Viral RNA Sampling for RT-qPCR

Study Overview
=================
Brief Summary
-----------------
The main objective of the tests is to establish saliva collection with Salivette® Cortisol.

Official Title
-----------------
COVID-19 Tests: a Systematic Comparison of Viral RNA Test Sample Taking for RT-qPCR, in This Case With a Nasopharyngeal Swab or Saliva Collected With Salivette® Cortisol, to Diagnose SARS-CoV-2 Virus Infection

Conditions
-----------------
Covid-19

Intervention / Treatment
-----------------
* Diagnostic Test: Sampling of SARS-CoV-2 RNA from nasopharyngeal swab specimen or saliva collected via Salivette Cortisol


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Informed consent form signed and dated before any samples have been taken. Suspected or confirmed SARS-CoV-2 infection by PCR within the past five days. Male and/or female patients aged 18 years and over.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Interventional Model Description: Comparison of SARS-CoV-2-RNA detectability in Swab and Salivette samples.
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Overall (Swab/Saliva)<br> | Diagnostic Test: Sampling of SARS-CoV-2 RNA from nasopharyngeal swab specimen or saliva collected via Salivette Cortisol<br>* Kylt® for detection/confirmation of SARS-CoV-2 cobas® SARS-CoV-2 (PCR) test TaqPath™ COVID-19 CE-IVD RT-PCR kit<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of Participants Testing Positive or Negative for SARS-CoV-2 Virus From Swab and Saliva Samples - Processed in Mexico | Number of participants testing positive or negative for SARS-CoV-2 virus from sample collected via swab versus saliva sample collected from Salivette® Cortisol, which samples were processed in Mexico. | At baseline (the test day), up to one day. | 
| Percentage of Participants Testing True Positive or True Negative for SARS-CoV-2 Virus From Swab and Saliva Samples - Processed in Germany | Percentage of participants testing true positive or true negative for SARS-CoV-2 virus from Swab and Saliva samples being processed in Germany was reported. The swab sample was used as the reference. Among participants who were tested positive from swab samples, those who were tested positive from saliva samples were classified as true positive. Among participants tested negative from swab samples, those who were tested negative from saliva samples were then classified as true negative. | At baseline (the test day), up to one day. |
Cognitive Correlates of Substance Abuse, Part 2 - 16

Study Overview
=================
Brief Summary
-----------------
Part II: Examine cognitive performance of stimulant abusers (methamphetamine and cocaine) during recovery by assessing their cognitive function at monthly intervals.

Detailed Description
-----------------
Part II: Examine cognitive performance of stimulant abusers (methamphetamine and cocaine) during recovery by assessing their cognitive function at monthly intervals.

Official Title
-----------------
Cognitive Correlates of Substance Abuse, Part 2

Conditions
-----------------
Amphetamine-Related Disorders

Participation Criteria
=================
Eligibility Criteria
-----------------
Please contact site for information Inclusion Criteria: M/F. Meet DSM-IV criteria for stimulant dependence. Agree to conditions of the study and sign informed consent.
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
A Trial to Compare the Outcome of Localised Varicosity Compression for 24 Hours and 5 Days After Foam Sclerotherapy to Truncal Varices

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to compare the results of foam treatment of varicose veins (foam sclerotherapy) in patients who wear compression bandages for 24 hours or 5 days after treatment.

Official Title
-----------------
A Randomised Controlled Trial to Compare the Outcome of Localised Varicosity Compression for 24 Hours and 5 Days After Foam Sclerotherapy to Truncal Varices

Conditions
-----------------
Varicose Veins

Intervention / Treatment
-----------------
* Device: Compression bandaging


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Proven truncal venous incompetence (of >1 second duration) on venous duplex scanning. (Great saphenous vein (GSV), small saphenous vein (SSV), anterior accessory thigh vein (AATV) or other major tributary). Agreed preference for foam sclerotherapy treatment. Signed consent form agreeing to be part of the trial. Exclusion Criteria: Total deep venous reflux. Known allergy to liquid sclerosant. Pregnancy or breast feeding. Arterial disease.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: 24 hours compression bandaging<br> | Device: Compression bandaging<br>* Cotton wool padding will then be placed over the treated vein and secured in place by crepe bandaging. An above-knee TED stocking will be applied on top of this.<br>|
| Active Comparator: 5 days compression bandaging<br> | Device: Compression bandaging<br>* Cotton wool padding will then be placed over the treated vein and secured in place by crepe bandaging. An above-knee TED stocking will be applied on top of this.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Aberdeen Varicose Vein Score from time of treatment to 2 and 6 weeks after treatment |  | 2 and 6 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Burford pain score from time of treatment to 2 and 6 weeks after treatment |  | 2 and 6 weeks | 
| Change in SF-36 score from time of treatment to 6 weeks after treatment. |  | 6 weeks | 
| Target vein occlusion rate on duplex imaging at 6 weeks |  | 6 weeks | 
| Number and type of complications seen |  | 6 weeks | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
varicose veins, foam sclerotherapy, compression bandaging, duration
Impact of a Checklist on the Rate of Late Cancellation in Ambulatory Surgery

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to evaluate the impact of a check list on the rate of late cancellation, i.e. the day before or the day of the ambulatory surgery.

Detailed Description
-----------------
The checklist is administered to the patients by phone between 7 and 3 days before the surgery. Each item of the checklist is associated with a decisional algorithm that allows take care for patients in case of any problem.

Official Title
-----------------
Impact of a Checklist on the Rate of Late Cancellation in Ambulatory Surgery

Conditions
-----------------
Ambulatory Surgery Programmed

Intervention / Treatment
-----------------
* Other: Checklist


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patient (adult or minor) for which ambulatory surgery is programmed in a multipurpose ASU Surgery under general anesthesia or loco Regional or neuroleptanalgesia3. Patient contacted by phone Patient does not oppose his participation in the study Exclusion Criteria: Patient programmed for endoscopy in ASU non surgical Ambulatory surgery scheduled for orthogenic Ambulatory surgery scheduled for urgency Ambulatory surgery performed under local anesthesia
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Administration of the checklist<br>Patients will be contacted by phone for administration of the checklist | Other: Checklist<br>* he checklist will be administered to the patients by phone between 7 and 3 days before the surgery<br>|
| No Intervention: No contact by phone<br>Patients who will not be contacted by phone | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Decrease in the rate of late cancellation |  | At day 0 (the day of the surgery) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Improvement of the organization of the ambulatory unit |  | At day 0 (the day of the surgery) | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Ambulatory surgery, Checklist, Cancellation
Study of Oral ENMD-2076 Administered to Patients With Ovarian Cancer

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to determine whether oral ENMD-2076 is effective in treatment of patients with platinum resistant ovarian, fallopian, or peritoneal cancer. Additional sites to be added.

Official Title
-----------------
A Phase 2 Study of Oral ENMD-2076 Administered to Patients With Platinum Resistant Ovarian Cancer

Conditions
-----------------
Ovarian Cancer, Fallopian Cancer, Peritoneal Cancer

Intervention / Treatment
-----------------
* Drug: ENMD-2076


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Have histologically documented diagnosis of ovarian, fallopian or peritoneal cancer that is platinum resistant. Have a pre-study echocardiogram or multigated acquisition (MUGA) scan with an actual left ventricular ejection fraction of greater than or equal to the institution lower limit of normal Greater than or equal to 18 years of age Have clinically acceptable laboratory screening results Have an ECOG performance status of 0 or 1 Able to tolerate oral medications Exclusion Criteria: Have uncontrolled hypertension (systolic blood pressure greater than 150mmHg or diastolic blood pressure greater than 100mmHg); require two or more antihypertensive medications to control hypertension (including ACE inhibitors, beta blockers, calcium channel blockers, or diuretics) Have chronic atrial fibrillation or QTc interval corrected for heart rate of greater than 470 msec Have active, acute, or chronic clinically significant infections or bleeding Have persistent 2+ protein by urinalysis or a history of nephrotic syndrome

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: ENMD-2076 treatment<br> | Drug: ENMD-2076<br>* 275 mg (or 250 mg for BSA < 1.65) per day in oral capsules in 28 day continuous cycles<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Progression free survival rate |  | 6 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
ovarian, platinum resistant ovarian cancer
Laryngeal Mask Airway for Adenoidectomies (LMAA)

Study Overview
=================
Brief Summary
-----------------
The current study retrospectively assesses laryngeal mask airway use during pediatric adenoidectomies in terms of patient safety, comfort, complications and surgeon satisfaction levels.

Official Title
-----------------
The Use of Laryngeal Mask Airway for Adenoidectomies: An Experience of 814 Paediatric Patients

Conditions
-----------------
Adenoidectomy Surgery, Flexible-Laryngeal Mask Airway

Intervention / Treatment
-----------------
* Other: Flexible-Laryngeal Mask Airway


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 1-16 years of age ASA I-II Scheduled for elective adenoidectomy under general anesthesia with F-LMA between June 2012 and November 2015. Exclusion Criteria: Emergency Extreme obesity Sign of clinical significant infection.

Ages Eligible for Study
-----------------
Minimum Age: 1 Year
Maximum Age: 16 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Health Services Research
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: F-LMA group<br>LMA were placed to 814 patients for adenoidectomy surgery. Researchers evaluated flexible laryngeal mask airway use during pediatric adenoidectomies in terms of patient safety, comfort, complications and surgeon satisfaction levels. | Other: Flexible-Laryngeal Mask Airway<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The incidence of failed LMA (0=failed, 1=good) |  | 3 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Surgeon satisfaction level (0=bad, 1=same, 2=good) |  | 3 year |
Impact of Bevacizumab on Symptom Burden and Neurological Deficits in Patients With Recurrent Glioblastoma

Study Overview
=================
Brief Summary
-----------------
This retrospective non - interventional patient chart review will be utilizing real world clinical data from patients treated for rGBM at the University Regensburg Medical center either with or without bevacizumab. Only patients will be analyzed who were potentially eligible for bevacizumab treatment. The study is designed to investigate the potential effects of bevacizumab treatment on the functional status, symptom burden, neurological deficits, time to tumor progression and overall survival between cohorts potentially eligible for bevacizumab.

Official Title
-----------------
Impact of Bevacizumab on Symptom Burden and Neurological Deficits in Patients With Recurrent GBM: A Retrospective Patient Chart Review

Conditions
-----------------
Glioblastoma, Angiogenesis

Intervention / Treatment
-----------------
* Other: Observation of neurological deficits


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Diagnosis of recurrent glioblastoma Exclusion Criteria: Severe neurocognitive deficits

Ages Eligible for Study
-----------------
Minimum Age: 18 Years


Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| A<br>Treatment without bevacizumab | Other: Observation of neurological deficits<br>* Observation of neurological deficits<br>|
| B<br>Treatment with bevacizumab | Other: Observation of neurological deficits<br>* Observation of neurological deficits<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Functional outcome | Neurological deficits impacting functional independency | 15 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Glioblastoma, Angiogenesis
Health and Psychological Outcomes of Lifestyle Versus Traditional Physical Activity

Study Overview
=================
Brief Summary
-----------------
This study is a comparison of the traditional prescription versus the lifestyle exercise prescription in sedentary adults over 6 months. Biological and psychological parameters will be assessed over the 6 month study. Biological indicators will be assessed pre and post including body composition, muscular strength, endurance, and flexibility, aerobic fitness, and blood tests. Psychological parameters will be assessed pre, mid, and post including self-efficacy, motivation, need satisfaction, physical self-description, leisure-time exercise, as well as all constructs from the thepry of planned behaviour.

Official Title
-----------------
Health and Psychological Outcomes of Lifestyle Versus Traditional Physical Activity- Study 1

Conditions
-----------------
Sedentary Behaviour, Adherence, Traditional Exercise, Lifestyle Exercise

Intervention / Treatment
-----------------
* Behavioral: traditional vs. lifestyle exercise


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 25-65 years old exercise less than twice per month in the preceeding 6 months physician consent to participate Exclusion Criteria: health problems exercise more than twice per month in the preceeding 6 months

Ages Eligible for Study
-----------------
Minimum Age: 25 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: traditional vs. lifestyle exercise|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
adherence, lifestyle, exercise, pedometer, training
Prehospital Minutes Count During a Stroke.

Study Overview
=================
Brief Summary
-----------------
The ultimate objective is to improve the efficacy of prehospital procedures for patients suffering an acute stroke. Increased precision in prehospital selection and a more efficient transport chain will lead to an even more rapid start of treatment and thus benefit patients. The research project has two parts: one part collecting data from medical reports and one study with qualitative in-depth interviews. The project will gather data from various parts of Norway and from a University hospital in Switzerland for comparison between regions and countries. Data will be retrieved through intrahospital and prehospital medical records from various parts of Norway (Nordland Hospital, Akershus University Hospital and Helgeland Hospital) and from Basel University hospital in Switzerland. Knowledge of factors associated with delays will be compared for regions in the north and south of Norway, as well as abroad. The information obtained will be analysed to identify components in the chain that may be improved as concerns time saving.

Official Title
-----------------
Prehospital Minutes Count During a Stroke. Factors Associated With Prehospital Delays With Data From Various Regions in Norway and One Region in Switzerland

Conditions
-----------------
Stroke, Acute

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: • Final diagnosis of stroke at discharge from hospital Exclusion Criteria: • Hospital admission later than one week from stroke onset

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Nordlandssykehuset HF<br> | |
| Akershus universitetsssykehus<br> | |
| Helgelandssykehuset<br> | |
| Basel University Hospital<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Time delay from ictus to hospital arrival | Delay from first symptoms of stroke until arrival at hospital | Within 4 hours |