Factors Associated With Dermatoporosis

Study Overview
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Brief Summary
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Dermatoporosis is a chronic syndrome of skin insufficiency or fragility. It is characterized by cutaneous atrophy, senile purpura and stellate pseudoscars. Dermatoporosis prevalence is 37% in ≥65 years. The objective was to determine factors associated with this diagnosis in >60 years old patients of the outpatient clinic in the Hospital Central Dr. Ignacio Morones Prieto  San Luis Potosí, México. An observational, cross-sectional, descriptive, and analytical study was performed. Patients >60 years old were selected. A clinical history, clinical examination, and application of a validated diagnostic self-questionnaire were performed.

Detailed Description
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Dermatoporosis is a chronic syndrome of skin insufficiency or fragility. It is characterized by cutaneous atrophy, senile purpura and stellate pseudoscars. Dermatoporosis prevalence is 37% in ≥65 years.The objective was to determine factors associated with this diagnosis in >60 years old patients of the outpatient clinic in the Hospital Central Dr. Ignacio Morones Prieto  San Luis Potosí, México. An observational, cross-sectional, descriptive and analytical study was performed. Through consecutive non-probabilistic sampling, patients > 60 years old were selected, who underwent a clinical history, clinical examination, and the application of a validated diagnostic self-questionnaire. To determine the association of the factors, a multivariate logistic regression analysis, it will be used the PRIMERv6 software with the PERMANOVA package. A p <0.05 was considered significant. The normality of the distribution of the continuous variables was evaluated with the Shapiro Wilk test. The Student's t test was performed on variables that met the homogeneity of variance requirements. In the variables that did not meet this criterion, a non-parametric analysis was performed with the Mann U Whitney test. For the analysis of categorical variables, Fisher's exact test or chi-square test was used. Continuous variables were reported by mean (median) [Q1, Q3] (min - max) and by standard deviations as their distribution corresponds. Nominal categorical variables were expressed as frequencies

Official Title
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Factors Associated With Dermatoporosis

Conditions
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Senile Purpura

Intervention / Treatment
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* Other: Questionnaire about associated factors
* Diagnostic Test: Self questionnaire diagnostic tool
* Other: Physical Examination


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients over 60 years Exclusion Criteria: Patients in whom physical examination cannot be performed due to the use of orthopedic devices such as splints, bandages, etc. Patients with whom interviewer-patient verbal communication is difficult due to some hearing or neurological deficit. Patients with neurological, psychiatric disorders who are unable to provide reliable information. (disorganized, incoherent speech, cognitive deficit)

Ages Eligible for Study
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Minimum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Cases<br>Patients diagnosed with dermatoporosis. A clinical history, physical examination, and application of a previously validated diagnostic self-questionnaire were performed. | Other: Questionnaire about associated factors<br>* Questionnaire about age, prolonged sun exposure, intake of anticoagulants / antiplatelets, intake of oral steroids, chronic kidney disease. Maternal age> 40 years in their last child , time of lactation per pregnancy and cumulative time of lactation. Age of the first pregnancy and age of menopause onset.<br>Diagnostic Test: Self questionnaire diagnostic tool<br>* Self questionnaire of physical characteristics<br>Other: Physical Examination<br>* Physical Examination made by a dermatologist<br>|
| Control<br>Patients not diagnosed with dermatoporosis. A clinical history, physical examination, and application of a previously validated diagnostic self-questionnaire were performed. | Other: Questionnaire about associated factors<br>* Questionnaire about age, prolonged sun exposure, intake of anticoagulants / antiplatelets, intake of oral steroids, chronic kidney disease. Maternal age> 40 years in their last child , time of lactation per pregnancy and cumulative time of lactation. Age of the first pregnancy and age of menopause onset.<br>Diagnostic Test: Self questionnaire diagnostic tool<br>* Self questionnaire of physical characteristics<br>Other: Physical Examination<br>* Physical Examination made by a dermatologist<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Factors associated with Dermatoporosis | Presence of factors related to age, sex, personal history of diseases, chronic oral treatments, gyneco-obstetrics background, chronic photoexposure | At time of enrollment | 
| Diagnostic by self assesment tool | Diagnostic of dermatoporosis made by self assesment tool | At time of enrollment | 
| Physical examination | Presence of pseudoscars (stellate scars) in the physical examination | At time of enrollment | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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purpura, dermatoporosis, senile