Combined Spinal-epidural Versus Spinal Analgesia for Elective Caesarean Section in the Postoperative Period

Study Overview
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Brief Summary
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Combined spinal epidural (CSEA) and single shot spinal anesthesia (SSSA) are both well-established anesthetic methods for caesarean section. CSEA combines the advantages of spinal anesthesia for the surgery, and epidural anesthesia for postoperative pain management. The aim of this randomized trial was to compare analgesia and patient satisfaction with CSEA continuous epidural administration of local anesthetics versus SSSA with oral pain medication in the postoperative period.

Detailed Description
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Combined spinal epidural (CSEA) and single shot spinal anesthesia (SSSA) are both well-established anesthetic methods for caesarean section. CSEA combines the advantages of spinal anesthesia for the surgery, and epidural anesthesia for postoperative pain management. However, it is more time-consuming, and adds potentially risks of both single techniques. The aim of this randomized trial was to compare analgesia and patient satisfaction with CSEA continuous epidural administration of local anesthetics versus SSSA with oral pain medication in the postoperative period.

Official Title
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Combined Spinal-epidural Versus Spinal Analgesia for Elective Caesarean Section in the Postoperative Period

Conditions
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Satisfaction, Pain

Intervention / Treatment
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* Procedure: caesarean section


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: American Society of Anesthesiologists-physical status: I or II elective caesarean section Exclusion Criteria: age under eighteen maternal systemic diseases allergies against the drugs used systemic infection or local infection in the puncture area dysfunctional coagulation coagulation-inhibiting drugs

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| single shot spinal anesthesia<br>single shot spinal anesthesia for caesarean section was executed for anesthesia, oral analgesic medication was applicated for postoperative analgesia. | Procedure: caesarean section<br>* elective caesarean section under regional anesthesia<br>|
| combuned spinal epidural anesthesia<br>combined spinal epidural anesthesia for caesarean section was executed for anesthesia, epidural and oral analgesic medication was applicated for postoperative analgesia. | Procedure: caesarean section<br>* elective caesarean section under regional anesthesia<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| patient's satisfaction | Standardised questionnaire assessing pain, discomfort, anxiety | perioperative | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| additional oral pain medication | Assessment of additionally requested oral pain medication | perioperative | 
| pain score | Standardised questionnaire assessing pain by using the visual analogue scale | perioperative |