Passive Leg Raise During Cardiopulmonary Resuscitation

Study Overview
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Brief Summary
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during cardiopulmonary resuscitation, an important element of the procedure is to achieve optimal organ perfusion. For this purpose, high quality chest compressions is one of the basic elements of the procedure. however, similarly as in the case of hypovolemic shock, elevation of the lower limbs may be helpful. The study is a randomized cross-over study and includes the effect of lower limb elevation on hemodynamic parameters in healthy participants.

Official Title
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Impact of Passive Leg Raise on Hemodynamic Effect: A Randomized Crossover Experimental Study

Conditions
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Leg Elevation, Hemodynamic Instability, Cardiopulmonary Resuscitation

Intervention / Treatment
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* Procedure: Hemodynamics parameters


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: healthy participants voluntary informed consent Exclusion Criteria: hip injury during the six months preceding the examination back pain kidney damage

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: None Elevation<br>Participant placed on a flat surface. Study participant connected to the measuring hemodynamic parameters device | Procedure: Hemodynamics parameters<br>* real-time evaluation of cardiac output parameters using the ICON device<br>|
| Experimental: Elevation angle of 20 degrees<br>Participant placed on a flat surface, lower limbs raised and supported at an angle of 20 degrees. Study participant connected to the measuring hemodynamic parameters device | Procedure: Hemodynamics parameters<br>* real-time evaluation of cardiac output parameters using the ICON device<br>|
| Experimental: Elevation angle of 30 degrees<br>Participant placed on a flat surface, lower limbs raised and supported at an angle of 30 degrees. Study participant connected to the measuring hemodynamic parameters device | Procedure: Hemodynamics parameters<br>* real-time evaluation of cardiac output parameters using the ICON device<br>|
| Experimental: Elevation angle of 45 degrees<br>Participant placed on a flat surface, lower limbs raised and supported at an angle of 45 degrees. Study participant connected to the measuring hemodynamic parameters device | Procedure: Hemodynamics parameters<br>* real-time evaluation of cardiac output parameters using the ICON device<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cardiac output - CO | the volume of blood that the heart pumps into blood vessels in one minute. It is the product of the frequency of heart contractions (HR) and stroke volume (SV). The parameter is measured using ICON device | during procedure | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Stroke Volume - SV | the amount of blood pressed through one of the heart chambers into the appropriate arterial reservoir during a single heart contraction. The parameter is measured using ICON device | during procedure | 
| thoracic fluid content - TFC | It is an indicator of total fluid volume, both intracellular and extracellular. The parameter is measured using ICON device | during procedure | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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cardiopulmonary resuscitation, hemodynamic, medical simulation, leg elevation