Evolution of Two Cohorts of Children (Univentricular and Bi-ventricular Heart) After Strapping of the Pulmonary Artery

Study Overview
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Brief Summary
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Pulmonary artery strapping is a surgical technique aimed at providing a palliative treatment to newborns suffering from congenital heart defects, characterized by an increase in blood flow and pulmonary blood pressure. The intervention consists of placing a band around the pulmonary artery. This band causes an artificial stenosis, therefore inducing a reduction of the pulmonary arterial pressure. It acts as a first step, preparing the ground for a future definitive repair intervention. It is mainly used in the context of septal defects, atrio-ventricular canal defects or uni-ventricular hearts. The complications linked to strapping include, among others, the erosion of the band in the artery lumen, its migration and the obstruction of the pulmonary artery, a pulmonary valvular insufficiency, the obstruction of the coronary artery and an ineffective strapping. The early mortality rate of pulmonary artery strapping after 1980 varies between 1.8% and 13.6%, while strapping readjustment rates oscillate around 20%. It is assumed that the mortality is linked to the nature of the cardial malformation (uni-ventricular or bi-ventricular) rather than the procedure itself. This retrospective study aims to evaluate the intra-hospital and extra-hospital mortality rate of pulmonary artery strapping, as well as the readjustment rate within two groups of patients: those benefiting from an uni-ventricular cardiac reparation and those benefiting from a bi-ventricular cardiac reparation. The aim is to determine the short term mortality rate of the intervention and the incidence of complications within the hospital, within the two groups.

Official Title
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Evolution of Two Cohorts of Children (Univentricular and Bi-ventricular Heart) After Strapping of the Pulmonary Artery

Conditions
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Congenital Heart Malformations

Intervention / Treatment
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* Other: Retrospective data extraction in medical files


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All patients treated with pulmonary artery strapping between 2005 and 2016 at the Queen Fabiola Children Hospital Exclusion Criteria: Outdated indications
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Uni-ventricular reparation<br>All patients treated with pulmonary artery strapping between 2005 and 2016 at the Queen Fabiola Children Hospital. Patients benefiting from an uni-ventricular reparation. | Other: Retrospective data extraction in medical files<br>* Retrospective data extraction in medical files<br>|
| Bi-ventricular reparation<br>All patients treated with pulmonary artery strapping between 2005 and 2016 at the Queen Fabiola Children Hospital. Patients benefiting from an bi-ventricular reparation. | Other: Retrospective data extraction in medical files<br>* Retrospective data extraction in medical files<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Date of birth | Date of birth of the patient | 12 years | 
| Sex | Sex of the patient | 12 years | 
| Weight | Weight of the patient at the time of the intervention | 12 years | 
| Exact diagnosis | Exact diagnosis at the time of the intervention | 12 years | 
| Exact date of intervention | Exact calender date of intervention | 12 years | 
| Total number of interventions | Total number of interventions | 12 years | 
| SpO2 | pre-surgery oxygen saturation | 12 years | 
| Date of death | If applicable, date of death of the patient | 12 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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pulmonary artery strapping