Prevalence of Dementia and Delirium in Outpatient Clinics (DESTAN Trial)

Study Overview
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Brief Summary
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The aim of this study is to assess the prevalence and etiologic risk factors of delirium in outpatient geriatric patients and also hospitalized patients.

Detailed Description
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This study aimed to investigate the frequency of delirium and examines the association between delirium and other possible risk factors and prognostic factors (dementia etc.)

Official Title
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Gulhane Training and Research Hospital

Conditions
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Delirium in Old Age, Delirium Superimposed on Dementia, Delirium With Dementia

Intervention / Treatment
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* Diagnostic Test: Confussion assessment method (CAM)
* Diagnostic Test: Dementia diagnosis


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: We included all 65 years older patients who evaluated according to a comprehensive geriatric assessment that is consistently performed during admission to the outpatients' clinic of the hospital. Exclusion Criteria: Exclusion criteria were serious psychiatric disorders such as schizophrenia or major depression.

Ages Eligible for Study
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Minimum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Delirium with dementia<br>Delirium was detected using the short form of the Confusion Assessment Method (CAM) both at admission and daily throughout the hospital stay. Cognitive status was determined using the Mini-Mental State Exam, Clinical Dementia Rating (CDR). Dementia was defined by a CDR score of 1. The primary independent variable was a composite of delirium and dementia diagnosis, and we examined the overlap by categorizing the cases into four groups: no delirium or dementia, dementia alone, delirium alone, and DSD. | Diagnostic Test: Confussion assessment method (CAM)<br>* Participants enrolled in the Delirium group according to the CAM.<br>Diagnostic Test: Dementia diagnosis<br>* Participants enrolled in the Dementia group according to the CDR scores and MMSE scores and DSM4/5 criteria<br>|
| Dementia without Delirium<br>Delirium was detected using the short form of the Confusion Assessment Method (CAM) both at admission and daily throughout the hospital stay. Cognitive status was determined using the Mini-Mental State Exam, Clinical Dementia Rating (CDR). Dementia was defined by a CDR score of 1. The primary independent variable was a composite of delirium and dementia diagnosis, and we examined the overlap by categorizing the cases into four groups: no delirium or dementia, dementia alone, delirium alone, and DSD. | Diagnostic Test: Dementia diagnosis<br>* Participants enrolled in the Dementia group according to the CDR scores and MMSE scores and DSM4/5 criteria<br>|
| Delirium without Dementia<br>Delirium was detected using the short form of the Confusion Assessment Method (CAM) both at admission and daily throughout the hospital stay. Cognitive status was determined using the Mini-Mental State Exam, Clinical Dementia Rating (CDR). Dementia was defined by a CDR score of 1. The primary independent variable was a composite of delirium and dementia diagnosis, and we examined the overlap by categorizing the cases into four groups: no delirium or dementia, dementia alone, delirium alone, and DSD. | Diagnostic Test: Confussion assessment method (CAM)<br>* Participants enrolled in the Delirium group according to the CAM.<br>|
| No dementia, No delirium<br>Delirium was detected using the short form of the Confusion Assessment Method (CAM) both at admission and daily throughout the hospital stay. Cognitive status was determined using the Mini-Mental State Exam, Clinical Dementia Rating (CDR). Dementia was defined by a CDR score of 1. The primary independent variable was a composite of delirium and dementia diagnosis, and we examined the overlap by categorizing the cases into four groups: no delirium or dementia, dementia alone, delirium alone, and DSD. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| frequency of Mortality | 1st year mortality according to the electronic national data base | 1 year fellow-up | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Delirium, Dementia, Mortality, Etiology, Outpatient