Antenatal Ultrasound Diagnosis of Periventricular Pseudocysts and Postnatal Outcome

Study Overview
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Brief Summary
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The present study aims to improve the information given to the parents during the screening of periventricular pseudocysts in the Pluridisciplinary Center of Prenatal Diagnosis, with retrospective cases screened during the last 5 years in university hospital of Bordeaux.

Detailed Description
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Antenatal ultrasound screening for periventricular pseudocysts is steadily increasing, enabled in part by technological advances in ultrasound equipment. Most of studies dealing with periventricular pseudocysts and subsequent neurodevelopment are based on neonatal screening, mostly performed in neonatal units. Current data in the literature on the postnatal outcome of children screened antenatally are scarce; there are only 5 cohort studies with small numbers on the subject. The present study aims to improve the information given to the parents during the screening of periventricular pseudocysts in the Pluridisciplinary Center of Prenatal Diagnosis, with retrospective cases screened during the last 5 years in university hospital of Bordeaux.

Official Title
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Antenatal Ultrasound Diagnosis of Periventricular Pseudocysts and Postnatal Outcome

Conditions
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Periventricular Pseudocysts

Intervention / Treatment
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* Other: questionnaire


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adult patient diagnosed with a periventricular cyst during a prenatal ultrasound at Bordeaux University Hospital between January 1, 2016 and December 31, 2020. Patient affiliated with or benefiting from a social security plan. Oral informed consent. Exclusion Criteria: Subarachnoid cyst Blake's pouch cyst Choroid plexus cyst Periventricular leukomalacia Poor understanding of French Patient under legal protection.

Ages Eligible for Study
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Minimum Age: 0 Years
Maximum Age: 5 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Intervention Model: Single Group Assignment
Interventional Model Description: questionnaire on postnatal development
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: questionnaire<br>Questionnaire on postnatal development | Other: questionnaire<br>* questionnaire on postnatal development<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| postnatal child development | composite criterion as follows: Delayed acquisition is defined according to the standards of the Pediatric Society: age of sitting > 8 months, age of walking > 18 months, ability or not to associate 3 words at age 3. The use of a medical profession concerns follow-up by a speech therapist, a psychomotrician or a physiotherapist. It is not necessarily a periodic follow-up but a minimum of 2 consultations after the assessment consultation. The scoring defines 2 groups, children with 0 points considered with a normal post-natal development children with 1 point or more considered with a post-natal development disorder. | Baseline | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| mother's medical history | mother's medical history | Baseline | 
| medical history of the child | medical history of the child | Baseline | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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periventricular pseudocysts, postnatal development