Evaluate the Change in Iron, Vitamin D, and C-Reactive Protein Level (CRP) in a 12 to 24 Week Period

Study Overview
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Brief Summary
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The purpose of this study is to observe changes in iron status and vitamin D status during a 12-24 week supervised training program, specifically males and females between the ages of 30 and 50 years old.

Detailed Description
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Study subjects will be participants in a triathlon training program through the Avera Sports Institute in Sioux Falls, SD. This clinical study will examine changes in iron and vitamin D levels. Blood specimens will be collected at baseline and again after 3 and 6 months of participating in the training program.

Official Title
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Observational Study to Evaluate Changes in Iron, Vit-D, and CRP During a Twelve to Twenty-Four Week Supervised Triathlon Training Program

Conditions
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Anemia, Vitamin D Deficiency

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Males and premenopausal females between the ages of 30 and 50 years old Training through the Avera Sports Institute Triathlon Training Program Agree to keep diet, exercise and all current health habits stable during participation in the study Exclusion Criteria: Women who are pregnant, breastfeeding or planning to become pregnant Has a chronic disease that affects calcium or bone metabolism Has a chronic disease that affects iron metabolism or iron storage Has kidney disease Has any laboratory or biometric value that would indicate an issue for the safety of the study subject Is currently participating in another clinical research study

Ages Eligible for Study
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Minimum Age: 30 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Triathletes<br>Group of individuals who are participating in a triathlon training program at the Avera Sports Institute | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Iron level | Serum iron levels | baseline, 3 months, 6 months | 
| Vitamin D level | Serum Vitamin D 25(OH)D levels | Baseline, 3 months, 6 months | 
| C-Reactive Protein level | Serum C-reactive protein level | Baseline, 3 months, 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Ferritin level | Serum ferritin level | Baseline, 3 months, 6 months | 
| Hemoglobin level | Serum hemoglobin level | Baseline, 3 months, 6 months | 
| Hematocrit | Serum hematocrit level | Baseline, 3 months, 6 months | 
| Total Iron Binding Capacity level | Serum TBC level | Baseline, 3 months, 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Iron deficiency, Vitamin D deficiency, Anemia, Athletes, Triathletes, Triathlon