Comparing Cold Biopsy Forceps Versus Cold Snare Biopsy for Colon Polyps

Study Overview
=================
Brief Summary
-----------------
Comparing the efficacy of cold biopsy forceps versus cold snare biopsy for removing colon polyps.

Detailed Description
-----------------
Polyps were randomized to be treated with either CSP or CFP. After the initial polypectomy, additional EMR was performed at the polypectomy site to assess the presence of residual polyp tissue.

Official Title
-----------------
Randomized Controlled Trial Comparing Cold Biopsy Forceps Versus Cold Snare Biopsy for Colon Polyps

Conditions
-----------------
Colon Polyps

Intervention / Treatment
-----------------
* Procedure: Cold Biopsy forceps
* Procedure: Cold snare biopsy


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients older than 40 years old and patients who are receiving colonoscopies and patients who have colon polyps Exclusion Criteria: patients who have not agreed to the study patients with bleeding tendencies

Ages Eligible for Study
-----------------
Minimum Age: 40 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Cold biopsy forceps<br>Cold biopsy forceps for removal of colon polyps | Procedure: Cold Biopsy forceps<br>* removal of polyps using cold biopsy forceps<br>|
| Active Comparator: Cold Snare Biopsy<br>Cold snare biopsy for removal of colon polyps | Procedure: Cold snare biopsy<br>* Removal of colon polyps using cold snare biopsy<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Comparing the complete removal rate of cold biopsy forceps versus cold snare biopsy for removing colon polyps | We will investigate the complete removal rate of colon polyps by using two different methods, cold biopsy forceps or cold snare biopsy. After removal of polyps by one of these two methods, the remnant lesion will be biopsied to study if there are any remnant tissues in order to find out the complete removal rate. | up to 3 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bleeding rate after removal of colon polyps by using cold biopsy forceps or cold snare biopsy | We will investigate bleeding rate after removal of colon polyps by these two methods. Bleeding rate will be the number of patients who showed significant bleeding after the procedure divided by the total number of patients who will receive the procedure. Significant bleeding was determined to be ongoing bleeding for more than 30 seconds after the procedure | participants will be followed up for 1 month | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
cold biopsy forceps, cold snare biopsy