Effect of Avocado Honey (Apis Mellifera) on Anthropometric and Biochemical Parameters in Healthy Subjects: A Pilot Study

Study Overview
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Brief Summary
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Thirteen healthy subjects (5 males; 8 females) ages 25-50 years, with BMI (body mass index): <25 kg/m2 completed the study. The participants were selected randomly, either the control group (n= 7) or honey group (n= 6). Subjects of honey group consumed 25 g of honey each day for 4 weeks.

Detailed Description
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18 healthy participants (body mass index [BMI] <25 kg/m2) between 25-50 years of age were recruited, of which 13 subjects (male [n=5]) and female [n=8]) completed the study. The participants were allocated randomly either control group (n= 7) or honey group (n= 6). Subjects of honey group consumed 25 g of honey each day for 4 weeks. Participants of both groups did not undergo a special diet regimen, drug therapy, or change in their lifestyle, such as physical exercise, during the period of study. A 3- day food record including two weekdays and one weekend day was used to assess the habitual food intake of the participants prior to initiation of the trial and repeated each week of intervention. Also, dietary intake was calculated using the database Food Processor® (Version. 10.3.0.), including nutritional information of Mexican foods when they weren't on the list.

Official Title
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Effect of Avocado Honey (Apis Mellifera) on Anthropometric and Biochemical Parameters in Healthy Subjects: A Pilot Study

Conditions
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Healthy Subjects

Intervention / Treatment
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* Dietary Supplement: The consumption of avocado honey was analyzed


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Male Female Ages 25-50 years, BMI (body mass index): under 25 kg per m2. Exclusion Criteria: Not smoker Not have an allergy to honey Not pregnant, Not been previously diagnosed any disease resulting in metabolic disorders Not chronically use medications known to affect metabolism Not participate in greater than 3 hours of structured exercise per week. Female participants that used some kind of contraceptives

Ages Eligible for Study
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Minimum Age: 25 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: Control group 1<br> | |
| No Intervention: Control group 2<br> | |
| No Intervention: Control group 3<br> | |
| No Intervention: Control group 4<br> | |
| No Intervention: Control group 5<br> | |
| No Intervention: Control group 6<br> | |
| No Intervention: Control group 7<br> | |
| Experimental: Honey group 1<br> | Dietary Supplement: The consumption of avocado honey was analyzed<br>* The subjects of honey group consumed 25 g of honey each day for 4 weeks.<br>|
| Experimental: Honey group 2<br> | Dietary Supplement: The consumption of avocado honey was analyzed<br>* The subjects of honey group consumed 25 g of honey each day for 4 weeks.<br>|
| Experimental: Honey group 3<br> | Dietary Supplement: The consumption of avocado honey was analyzed<br>* The subjects of honey group consumed 25 g of honey each day for 4 weeks.<br>|
| Experimental: Honey group 4<br> | Dietary Supplement: The consumption of avocado honey was analyzed<br>* The subjects of honey group consumed 25 g of honey each day for 4 weeks.<br>|
| Experimental: Honey group 5<br> | Dietary Supplement: The consumption of avocado honey was analyzed<br>* The subjects of honey group consumed 25 g of honey each day for 4 weeks.<br>|
| Experimental: Honey group 6<br> | Dietary Supplement: The consumption of avocado honey was analyzed<br>* The subjects of honey group consumed 25 g of honey each day for 4 weeks.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Subject numbers that experienced a change of glucose level (mg/dL) post-intake of 25 g/day of honey |  | From the start of treatment (baseline) until 4 weeks | 
| Subject numbers that experienced change of triglycerides levels (mg/dL) post-intake of 25 g/day honey |  | From the start of treatment (baseline) until 4 weeks | 
| Subject numbers that experienced change of total cholesterol levels (mg/dL) post-intake of 25 g/day honey |  | From the start of treatment (baseline) until 4 weeks | 
| Subject numbers that experienced change of HDL-cholesterol levels (mg/dL) post-intake of 25 g/day honey |  | From the start of treatment (baseline) until 4 weeks | 
| Subject numbers that experienced change of LDL-cholesterol levels (mg/dL) post-intake of 25 g/day honey |  | From the start of treatment (baseline) until 4 weeks | 
| Subject numbers that experienced change of body weight (kg) post-intake of 25 g/day honey. |  | Frame: from the start of treatment (baseline) until 4 weeks | 
| Subject numbers that experienced change of body fat (%) post-intake of 25 g/day honey |  | From the start of treatment (baseline) until 4 weeks | 
| Subject numbers that experienced change of waist circumference (cm) post-intake of 25 g/day honey |  | From the start of treatment (baseline) until 4 weeks | 
| Subject numbers that experienced change of hip circumference (cm) post-intake of 25 g/day honey |  | From the start of treatment (baseline) until 4 weeks | 
| Subject numbers that experienced change of waist-hip ratio post-intake of 25 g/day honey |  | From the start of treatment (baseline) until 4 weeks | 
| Subject numbers that experienced change of BMI (weight (kg)/height (m)2) post-intake of 25 g/day honey |  | From the start of treatment (baseline) until 4 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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avocado honey, anthropometric parameters, biochemical parameters, natural sweetener