Effects of Massage Versus Rest on Hormones

Study Overview
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Brief Summary
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This study will investigate the effects of 15 minutes of massage compared to 15 minutes of quiet rest on physiological variables. Specifically, the investigators will measure the effects on levels of the social hormone oxytocin, and on other physiological variables that interact with oxytocin or that may be influenced by massage (including ACTH, Beta-endorphin, and IL-1alpha). The investigators will also investigate whether, in the case of hormones changes, these influence social decision making.

Detailed Description
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Interested participants will have the experiment explained both verbally and in writing, and asked to give their informed consent in writing. After consent, the participants will be led to a private room for their first 30ml blood draw by a qualified phlebotomist. Participants will then have a second 30ml blood draw.

Official Title
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Investigating the Effects of Massage vs. Rest on Oxytocin, ACTH, and B-endorphins

Conditions
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Massage, Rest

Intervention / Treatment
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* Procedure: Massage or Rest


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Anyone English speaking and over the age of 18. Exclusion Criteria: Minors and anyone who has used illicit drugs or alcohol in the last 24 hours.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Masking: Single


Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: Massage or Rest|Participants either received 15 minutes of moderate pressure Swedish massage on the upper back, or rested quietly sitting in a chair for 15 minutes.|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Oxytocin | Participants receive a blood draw at baseline and immediately following 15 minutes of massage or rest and oxytocin will be measured from this sample. | Within 5 minutes following experimental manipulation of either 15 minutes massage or rest. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Adrenocorticotrophic hormone (ACTH) | Participants will receive a blood draw at baseline and immediately following 15 minutes of massage or rest, and ACTH will be measured in these blood samples. | Within 5 minutes following experimental manipulation of either 15 minutes massage or rest. | 
| Beta-endorphin | Participants will receive a blood draw at baseline and immediately following 15 minutes of massage or rest, and B-endorphin will be measured from these samples. | Within 5 minutes following experimental manipulation of either 15 minutes massage or rest. | 
| Interleukin-1alpha (IL-1a) | Participants will receive a blood draw at baseline and immediately following 15 minutes of massage or rest, and IL-1a will be measured from these samples. | Within 5 minutes following experimental manipulation of either 15 minutes massage or rest. | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Massage, Rest