Influence of Olfaction Essential Oils on the Consumption of Benzodiazepine Receptor Agonists & Z-Drugs (BZRAs) Prescribed as  if Needed  in Psychiatric Outpatients (HECBA-PSY).

Study Overview
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Brief Summary
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The goal of this interventional study is to test the use of olfactory Essential Oils through a nasal stick as one of the non-medicinal strategies to propose to the patient to reduce the consumption of medication in a population of stabilized patients with psychiatric disorder. The main objective is to evaluate whether the olfaction of a mixture of essential oils can reduce the intake of BZRAs, prescribed if needed. The investigators want to compare the number of medications prescribed on if needed basis before and after the introduction of Essential Oils. A period prior to inclusion is used to assess the participant's frequency of BZRA use. Then, participants will received Essential Oils through a nasal stick during 4 weeks. During this period, the patient completes weekly anxiety and sleep scales and at the final visit, weekly and monthly anxiety and sleep scales.

Detailed Description
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It is a common in psychiatry for a physician to prescribe a patient, regardless of pathology, a treatment to be taken punctually in case of anxiety, nervousness, irritability or difficulty falling asleep. This if needed treatment can be add to the patient's usual treatment or constitute his only drug treatment. Most of the time, the if needed medication prescribed is a BZRA, which exposes the patient to the risk of creating dependency and drug abuse if the doses are multiplied. In this context, it seems interesting to us to test the use of olfactory Essential Oils through a nasal stick as one of the non-medicinal strategies to propose to the patient to reduce the consumption of medication. A two-week period prior to inclusion is used to assess the patient's frequency of BZRA use. During the pre-inclusion visit, the investigators explain the study protocol, the patient gives consent, and they are given a diary to record their BZRA use. (one of the inclusion criteria is more than 3 and less than 21). At the second visit, the patient fills out the anxiety and sleep questionnaire, the investigators perform an allergy test, and they receive an aromastick. At following visits, the patient completes weekly anxiety and sleep scales and at the final visit, weekly and monthly anxiety and sleep scales.

Official Title
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Influence of Olfaction Essential Oils on the Consumption of Benzodiazepine Receptor Agonists & Z-Drugs (BZRAs) Prescribed as  if Needed  in Psychiatric Outpatients (HECBA-PSY).

Conditions
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Psychiatric Disorder, Benzodiazepine Withdrawal

Intervention / Treatment
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* Drug: Essences and Essential Oils


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adult without legal protection measures Ambulatory followed up Stabilised main psychiatric pathology Patient having had recourse between 3 and 21 times a week in the previous 14 days to a benzodiazepine or related treatment, for anxiolytic or hypnotic purposes, prescribed if necessary (on request) Patient who understand French both orally and in writing Patient who do not have an identified organic cause for their disorder Patient who be affiliated to a social security scheme Patient who have given their free and informed consent and signed the consent form Exclusion Criteria: Patients with asthma or unstable epilepsy Pregnancy or breastfeeding EO allergies Patients having already a regular consumption of EO for the study indication Patients under guardianship or under reinforced guardianship

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Essential Oils<br> | Drug: Essences and Essential Oils<br>* Participants will received Essential Oils through a nasal stick during 4 weeks.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of medications prescribed | Compare the number of medications prescribed on if needed basis before and after the introduction of essential oils. | 4 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Anxiety level | STAI (State Trait Anxiety Inventory) scale | 4 weeks | 
| Sleep level | Pittsburgh Sleep Quality Index (PSQI) scale | 4 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Olfaction, Anxiety, Insomnia, Essential Oil, Psychiatry