Evaluating the Impact of Evidence-based Information About PSA Testing on Prostate Cancer Screening Decisions

Study Overview
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Brief Summary
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Patient decision aids are tools that help guide individuals through a healthcare-related decision making process. They help users combine evidence-based information and recommendations by a health care provider with their personal needs, values and preferences. Through this project, Dr. Dobbins and her research team will explore whether the use of patient decision aids with high-quality and user-friendly summaries of research evidence, or summaries of research evidence alone, help to improve the quality of decision making by men facing prostate cancer screening decisions.

Detailed Description
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Guidelines for prostate screening in Canada are based on low-moderate quality evidence of effectiveness and screening is associated with potential harms. Patient Decision Aids (PDAs) are tools that assist users to understand treatment options, risks and benefits to align decisions with values and preferences. The investigators would now like to know whether use of a PDA alongside evidence-based information provided through the McMaster Optimal Aging Portal, or simply access to evidence-based information alone, can help users to make informed decisions about prostate cancer screening in men.

Official Title
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McMaster Choices Study: Evaluating the Impact of Evidence-based Information About PSA Testing on Prostate Cancer Screening Decisions

Conditions
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Prostate Cancer

Intervention / Treatment
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* Other: Evidence-based information
* Other: Patient Decision Aid
* Other: Sham information


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: English speaking men, > 50 years old Exclusion Criteria: History of prostate cancer or PSA test in the last 12 months

Ages Eligible for Study
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Minimum Age: 50 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Screening
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Evidence + PDA<br>Evidence-based information on PSA testing such as blog posts, plain language evidence summaries and web resource ratings (quality-appraised online resources), plus a blog post on PDAs and the relevant decision aid from the Portal database | Other: Evidence-based information<br>* Evidence-based information on PSA testing such as blog posts, plain language evidence summaries and web resource ratings (quality-appraised online resources).<br>Other: Patient Decision Aid<br>* Patient Decision Aid for prostate cancer screening decision<br>|
| Experimental: Evidence only<br>The same evidence-based information as group 1 (Evidence + PDA), but without the PDA to quantify the effect of accessing evidence through the Portal alone | Other: Evidence-based information<br>* Evidence-based information on PSA testing such as blog posts, plain language evidence summaries and web resource ratings (quality-appraised online resources).<br>|
| Sham Comparator: Attention control<br>Information on how to distinguish high from low-quality health information, not specific to cancer screening or PDAs | Other: Sham information<br>* Educational information not specific to PSA testing or cancer screening<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Decisional conflict | Decisional Conflict Scale | Change from baseline to 6-mo | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Decision quality | Decision Quality Worksheet for PSA testing | Change from baseline to 6-mo | 
| Preparation for decision making | Preparation for decision making scale | Change from baseline to 6-mo | 
| Screening behaviour | Congruency between self-reported screening status and stated decision | Change from baseline to 6-mo | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Screening, PSA testing, Patient Decision Aid