Age-related Normative Values for the Octopus 900 Perimeter

Study Overview
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Brief Summary
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The purpose of this study is to determine normal values of the visual field (VF), corrected for age- and reaction time (RT) using the Octopus 900 perimeter and semi-automated kinetic perimetry (SKP).

Official Title
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Normal Values for the Full Visual Field, Corrected for Age- and Reaction Time, Using Semi-automated Kinetic Testing on the Octopus 900 Perimeter

Conditions
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Healthy

Intervention / Treatment
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* Device: Octopus 900 perimeter (Haag Streit AG, Koeniz, Switzerland)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: maximum spherical ametropia ± 6 Diopters (D) maximum cylindrical ametropia ± 2 D distant visual acuity ≥ 1.0 logMAR [20/20] for subjects up to 60 years, ≥ 0.8 logMAR [20/25] for subjects from 61-70 years, ≥ 0.63 logMAR [20/30] for subjects older than 70 years isocoria, pupil diameter > 3mm intraocular pressure (air pulse tonometer) ≤ 21mmHg normal anterior segments ocular fundus: normal appearance of the cup to disc ratio (CDR) ≤ 0.5, interocular difference of CDR < 0.3 normal macular region, vessels, and peripheral retinal examination (with undilated pupils). Exclusion Criteria: amblyopia strabismus ocular motility disorder diseases of the retina glaucoma, glaucoma suspect macular degeneration IOP > 21 mmHg abnormal color vision test (ISPP - Ishihara and Standard Pseudoisochromatic Plates = SPP) history or findings of other neuro-ophthalmological disease relevant opacities of the central refractive media (cornea, lens, vitreous body) use of miotic drugs intraocular surgery (except uncomplicated cataract surgery, more than three months previous to testing) kerato-refractive surgery (LASIK) drugs influencing reaction time drugs indicating severe general diseases (anti-diabetic pharmaceuticals and anti-hypertensive medication were allowed for subjects older than 70 years) mental diseases (for example psychosis) pregnancy, nursing acute infections heavy smoking (>10 cigarettes /day) alcohol abuse diabetic retinopathy coronary heart disease stroke migraine Raynaud's syndrome suspected lack of compliance

Ages Eligible for Study
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Minimum Age: 11 Years
Maximum Age: 79 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: one arm<br>observational study, no cohort, single group of different ages | Device: Octopus 900 perimeter (Haag Streit AG, Koeniz, Switzerland)<br>* We used the following six combinations of Goldmann8,1 stimulus size, stimulus luminance and angular velocity: V4e (64mm², 103', 320cd/m²) at 5°/s, III4e (4mm², 25.7', 320cd/m²) at 5°/s, I4e (0.25mm², 6.45', 320cd/m²) at 2°/s (for the assessment of the blind spot), I3e (0.25mm², 6.45', 100cd/m²) at 5°/s, I2e (0.25mm², 6.45', 32cd/m²) at 3°/s, I1e (0.25mm², 6.45', 10cd/m²) at 3°/s, I1a (0.25mm², 6.45', 4cd/m²) at 2°/s . The peripheral five isopters, consisting of 24 vectors (every 15° meridian), were presented in random order, while the innermost isopter (I1a) consisted of 12 vectors (every 30° meridian)<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Measurement of the full Visual Field using semi-automated kinetic perimetry. | additional a subgroup of 14 participants were tested at 3 separate sessions within 4 weeks. | one day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Norm values, semi-automated kinetic perimetry, isopters, mathematical model, luminance, test-retest reliability, deviation, age dependance, different age groups, Healthy subjects