Adhesion of Connective Tissue Around Laser-treated Abutments for Dental Implants - Clinical Trial in Humans

Study Overview
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Brief Summary
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This study aims to demonstrate the histological differences in the connective tissue surrounding laser-treated abutments and untreated abutments in humans. Working hypothesis: There are differences in the adhesion of collagen fibres around implant abutments with laser-produced microgrooves and standard abutments.

Detailed Description
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All patients will receive both abutment systems. The assignment of the abutments to each of the implants will be made randomly using SPSS 15.0 (SPSS Inc., Chicago, Il, United States) software.

Official Title
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Histological Differences in the Adhesion of Connective Tissue Around Laser-treated Abutments and Standard Abutments for Dental Implants - Clinical Trial in Humans

Conditions
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Periimplantitis

Intervention / Treatment
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* Procedure: Dental implant placement with a final prosthetic abutment


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patient must have partial edentulism of at least 2 teeth patients that have scheduled treatment for the placement of at least 2 implants patients with favourable attached gingiva patients without systemic diseases that would prevent the emplacement of implants patient must accept participation in the study by signing an informed consent form Exclusion Criteria: smokers of 1 or more cigarettes per day patients who suffer from any known condition that could be an absolute or relative contraindication to dental implant placement patients requiring any additional surgical technique for bone or gum graft in order to insert the dental implant patients who refuse to be included in the study or do not sign the informed consent form

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: LaserLok abutment<br>Laser microtexturing dental implant abutment | Procedure: Dental implant placement with a final prosthetic abutment<br> <br> |
| Active Comparator: 3inOne abutment<br>Standard dental implant abutment | Procedure: Dental implant placement with a final prosthetic abutment<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Connective tissue adhesion | At 90 days after the first operation, a second surgical procedure will be scheduled. A cilindrical scalpel of a diameter 2 mm greater than the abutment is used to make the incision and the abutment unscrewed together with the gingival insertion surrounding it for histological study. The attachment of connective tissue to the abutments will be determined by microscopic observation. It will be a binary variable: attachment IS present (YES-A); attachment IS NOT present (NO-A). | 3 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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LaserLok, connective tissue, adhesion