Health Related Quality of Life in Children With Food Allergy: Comparison to Controls and Other Chronic Diseases

Study Overview
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Brief Summary
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The number of studies concerning health related quality of life (HRQL) in children with food allergy is very limited. Only one study to date has compared HRQL of a group of children with food allergy to data published on general population and other chronic diseases. This study concluded to lowest HRQL scores in food allergic children compared to type 1 diabetes mellitus with important impact on scores concerning social activities.

Detailed Description
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Primary aim: To compare generic HRQL score in children with food allergy with other chronic diseases and with healthy chidren in an homogeneous socio-cultural context. Secondary aims : To compare generic and specific HRQL scores in children with food allergy Identifify in chidren with food allergy, clinical factrors assocated with lowest scores in order to improve our management. Methods Generic HRQL questionnaire (CHQ-87) will be distributed : after hospital consultation for patients in schools for healthy children A specific HRQL questionnaire (FAQLQ-CF or TF) and the  Food Allergy Independent Measure  will also distributed to chidren with food allergy.

Official Title
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Health Related Quality of Life in Children With Food Allergy: Comparison to Healthy Children and Children With Other Chronic Diseases

Conditions
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Children With Food Allergy

Intervention / Treatment
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* Other: filling questionnary to quality of life


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age between 8-18 year old IgE mediated food allergy diagnosed by a pediatric allergologist with following criteria: Convincing history of allergic reaction with positive prick-test and specific IgE Or Open food challenge associated with positive prick-test and specific IgE Signed informed consent of the two parents Signed informed consent of the child Health insurance recipient Exclusion Criteria: Association with another medical or psychiatric chronic disease (excepted for controlled asthma) Partially or not controlled asthma during last year No signed consent

Ages Eligible for Study
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Minimum Age: 8 Years
Maximum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Allocation: Non-Randomized
Intervention Model: Factorial Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: children with food allergy<br>Chidren aged 8-18 year with food allergy | Other: filling questionnary to quality of life<br>* filling questionnary to quality of life<br>|
| Active Comparator: children with chronic diseases<br> | Other: filling questionnary to quality of life<br>* filling questionnary to quality of life<br>|
| Active Comparator: witnesses<br>Inclusion criteria Age between 8-18 year old Children attending schools of Nice City Signed informed consent of the two parents Signed informed consent of the child Health insurance recipient Non inclusion criteria Association with another medical or psychiatric chronic disease No signed consent | Other: filling questionnary to quality of life<br>* filling questionnary to quality of life<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| comparison of12 scores of the generic health-related quality of life questionnaire CHQ-CF 87 between children with food allergy and healthy children scores. | 12 scores concerning the 12 following dimensions: physical functioning role functioning emotional role functioning behavior role functioning physical bodily pain general behavior mental health self-esteem general health change in health family activities family cohesion Comparison between children with food allergy and healthy children scores. | Once at inclusion | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| comparaison beetween all questionnary | Comparison of the CHQ-CF 87 scores between children with food allergy and chidren with other chronic diseases. Comparison of the CHQ-CF 87 scores with the FAQLQ-CF (or -TF) score (global and 4 dimensions) and with the FAIM score. Comparison of the FAQLQ-CF (or-TF) (global and 4 dimensions) with clinical characteristics of the children with food allergy | once at inclusion | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Health related quality of life, food allergy, children, chronic diseases