Taste Preferences for Nutritive and Non Nutritive Sweeteners Among Children and Adults

Study Overview
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Brief Summary
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The goal of the study is to determine whether there are age-, diet- and genetically-related differences in the perception of sweeteners, both nutritive and non-nutritive.

Detailed Description
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This is an observational 3-day study of children between the ages of 7 and 14 and their mothers. A variety of psychophysical methods determined liking for each of the sweeteners and saliva samples were obtained for genotyping of taste receptor genes. Anthropometric and dietary intake measures were also collected.

Official Title
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Taste Preferences for Nutritive and Non Nutritive Sweeteners Among Children and Adults

Conditions
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Development

Intervention / Treatment
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* Other: sweeteners


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Healthy Exclusion Criteria: Allergies and taking medication that affected taste

Ages Eligible for Study
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Minimum Age: 7 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Age Group-Children<br>Children between ages of 7 and 14 | Other: sweeteners<br>* Participants tasted a variety of nutritive and nonnutritive sweeteners<br>|
| Age Group-Adults<br>Healthy adults who are the parent of the children | Other: sweeteners<br>* Participants tasted a variety of nutritive and nonnutritive sweeteners<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Liking for the taste of sweeteners measured via the 3-point facial hedonic scale. |  | Through study completion, an average of 6 months. | 
| Liking for the taste of sweeteners measured via the 5-point facial hedonic scale |  | Through study completion, an average of 6 months. | 
| Liking for the taste of sweeteners measured via the Monell forced-choice, paired-comparison tracking procedure. |  | Through study completion, an average of 6 months. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Genotyping of taste receptor genes via saliva donation | Genotyping will be completed to measure associations between individual taste receptor genotypes and liking of sweeteners. | Through study completion, an average of 6 months | 
| BMI calculated from body weight and height measures | BMI will be calculated to examine associations between this measure and liking for sweeteners. | Through study completion, an average of 6 months | 
| One day dietary intake collected via the Automated Self-Administered 24-hour dietary recall (ASA24). | Dietary recall will be completed to examine associations between added sugar intake and liking for sweeteners. | Through study completion, an average of 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Sweet Taste, Psychophysics, Genetics, Diet, Age, Nonnutritive Sweetener