Intervention to Support Participation in Regular Exercise in the Elderly (INSPIRE)

Study Overview
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Brief Summary
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The investigators will conduct a 1-year prospective and randomized study to evaluate the initial efficacy of positive affect vs. an educational control to motivate physical activity in older adults with high burdens of chronic disease.

Detailed Description
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Older adults with multiple chronic diseases are at high risk for both disability and adverse clinical events, outcomes that can be improved with physical activity, but there have been no trials to establish physical activity recommendations or clinical guidelines for this vulnerable population. A recent randomized controlled trial conducted by Dr. Peterson established the efficacy of inducing positive affect-a feeling of happiness and well-being-in motivating physical activity in older adults with cardiovascular disease. This new randomized controlled trial will pilot test the a new PAIRE (Positive Affect Induction for Regular Exercise) intervention that is specific to older adults with multiple high-risk chronic illnesses versus an educational control group. This work is innovative because it will translate the benefits of a proven intervention focused on positive affect to increase physical activity in older adults with multiple high-risk chronic illnesses, one that is tailored to the clinical and psychosocial challenges of this particularly vulnerable population. This work is significant because an effective intervention promoting physical activity will improve outcomes for older adults with multiple high-risk chronic diseases, and currently one does not exist.

Official Title
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Intervention to Support Participation in Regular Exercise in the Elderly (INSPIRE)

Conditions
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Chronic Illnesses

Intervention / Treatment
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* Behavioral: Physical activity plus positive affect
* Behavioral: Physical activity plus education


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Charlson Index greater or equal to 3 Exclusion Criteria: Cognitive impairment Inability to walk < 12 month anticipated survival enrollment in other behavioral programs lack of medical approval to participate substance/alcohol dependence or participation in a substance abuse treatment program within 12 months major psychiatric illness.

Ages Eligible for Study
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Minimum Age: 60 Years
Maximum Age: 110 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Physical activity plus positive affect<br>Subjects will be randomized to a physical activity goal and the positive affect component | Behavioral: Physical activity plus positive affect<br>* Subjects will be randomized to a physical activity goal and will receive the positive affect component.<br>Behavioral: Physical activity plus education<br>* Subjects will be randomized to a physical activity goal and will receive the educational component.<br>|
| Active Comparator: Physical activity plus education<br>Subjects will be randomized to a physical activity goal and education | Behavioral: Physical activity plus education<br>* Subjects will be randomized to a physical activity goal and will receive the educational component.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Kilocalories/week assessed by Objective measure of activity with accelerometry | FitBit | baseline to 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Kilocalories/week assessed by Subjective measure of activity by self-report |  | baseline to 12 months | 
| Function/disability assessed by objective and subjective reports of functional ability |  | baseline to 12 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Physical activity, positive affect, older adults, aging