Pulse and Constitution of Pregnant Women

Study Overview
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Brief Summary
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The present project plans to detect pregnant pulses using this portable ANS (autonomic nervous system) Watch connected to a laptop. One hundred pregnant women and 100 non-pregnant women will be recruited.

Detailed Description
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ANS(autonomic nervous system) Watch has been developed as to detect pulse waves using a pressure detector. It is used to measured cardiovascular indices, including cardiac output, and vessel stiffness. ANSWatch is developed to apply to the prediction of traditional Chinese medicine (TCM) pulses, such as the wiry pulse. There are 28 types of pulses in TCM. Among them, the slippery pulse is the most commonly seen pulse in pregnant women. The present project plans to detect pregnant pulses using this portable ANSWatch connected to a laptop. One hundred pregnant women and 100 non-pregnant women will be recruited. After taking the indices of the subjects, a neural network is designed to provide the prediction for pregnancy constitution, pregnancy pulse and slippery pulse in pregnant women.

Official Title
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Prediction of Pregnancy Constitutions and Pregnancy Slippery Pulse Using ANSWatch

Conditions
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Pulse Wave, Pregnancy

Intervention / Treatment
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* Diagnostic Test: ANS Watch


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: nonpregnant females and singleton pregnant females aged 20 - 45 years; no estrogen, progesterone, or ovulation inducing medications were in the past six months Exclusion Criteria: active heart disease, liver disease, kidney disease, or thyroid disease; any chronic disease which needs medication smoking, drug abuse, or alcohol abuse; psychiatric disorders or impaired cognitive function; taking Chinese medicine or western medicine in three months; Acute conditions currently, such as gastroenteritis, upper airway infection, acute attach of asthma, etc.

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Pregnant<br>pregnant women | Diagnostic Test: ANS Watch<br>* ANS Watch will be used to record the pulse waves Constitution questionnaire will be used to measure the constitution type<br>* Other names: Constitution questionnaire;|
| Non-pregnant<br>non-pregnant women | Diagnostic Test: ANS Watch<br>* ANS Watch will be used to record the pulse waves Constitution questionnaire will be used to measure the constitution type<br>* Other names: Constitution questionnaire;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pulse waves | indices of the pulse waves measured by ANSWatch (https://www.taiwanscientific.com.tw/%E5%BF%83%E5%BE%8B%E5%A4%A7%E5%B8%ABanswatch). A neural network is designed to provide the prediction for pregnancy pulse. | Day 1 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Constitution | Nine constitutions will be measured using the Nine constitution Questionnaire (in Chinese). This questionnaire defines whether subjects have Yin-deficiency, Yang-deficiency, Qi-deficiency, Phlegm-dampness, Dampness-heat, Special dialesis, Blood-stasis, Qi-depression, and Neuture constitutions. | Day 1 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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pulse, pregnant women