Housing and Health Study

Study Overview
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Brief Summary
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The goal of the project is to examine the impact of providing housing for people living with HIV who are homeless or at imminent risk of homelessness on their HIV disease progression, risks of transmitting HIV, and medical care access and utilization.

Detailed Description
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Evidence is accumulating that homelessness and housing may be important factors that influence human immunodeficiency virus (HIV) sex and drug risk behaviors. Despite this apparent connection, few studies have investigated whether homelessness or unstable housing, compared with stable and adequate housing, is linked with HIV risk behaviors, and whether change in housing status is associated with change in risk behaviors. The Housing and Health Study is a multi-site, multi-agency research collaboration. This project is a unique collaboration between federal agencies (the Department of Housing and Urban Development and the Centers for Disease Control and Prevention), local government agencies, universities, and private not-for-profit organizations. The goal of the project is to examine the impact of providing housing for people living with HIV who are homeless or at imminent risk of homelessness on their disease progression, their risks of transmitting HIV, and medical care access and utilization. A total of 630 people living with HIV from three study sites complete the baseline study sessions. Half the participants (n=315) are randomly assigned to each of the two study groups. Treatment group participants receive Housing and Health Study housing rental assistance, and comparison group participants receive assistance finding housing according to local standard practice. At baseline, 6, 12, and 18 months after baseline, participants complete study questionnaires and provide blood specimens to test for CD4 and viral load. In addition, the cost effectiveness of the study will be investigated by examining the HIV-related costs averted by providing housing to persons at high risk for transmitting HIV.

Official Title
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Housing and Health Study

Conditions
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HIV, AIDS

Intervention / Treatment
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* Behavioral: Housing and Health Study housing rental assistance
* Behavioral: Standard local practice housing assistance


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: HIV seropositive At least 18 years of age English or Spanish speaking Able to provide informed consent Able to participate in data collection protocol Categorized as low income (less than 80% of the Area Median Income) Homeless or at imminent risk of homelessness Able to provide information about identity Exclusion Criteria: -

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Housing and Health Study housing rental assistance<br> | Behavioral: Housing and Health Study housing rental assistance<br> <br> |
| Active Comparator: Standard local practice housing assistance<br> | Behavioral: Standard local practice housing assistance<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| HIV risk behaviors at 6, 12, and 18 months |  |  | 
| Biological measures of HIV-related health status |  |  | 
| Access to HIV/AIDS medical care |  |  | 
| Adherence to HIV/AIDS medical care, including compliance with HIV medication therapies |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cost and cost effectiveness of the intervention |  |  | 
| Proximal outcomes (e.g., increased condom use self-efficacy, social norms) associated with a reduction in HIV risk behaviors |  |  | 
| Social contact, employment outcomes, quality of life, mental health |  |  | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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HIV, AIDS, Homeless, Homelessness, Housing, HIV seropositive, HIV risk behavior