Influence of Brief Supportive Psychotherapy on Major Adverse Cardiovascular Events, Neutrophil-lymphocytes Ratio and Psychological Symptoms in Acute Coronary Syndrome in Intensive Cardiac Care Unit

Study Overview
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Brief Summary
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There was no MACE in both groups, but there was stroke-major adverse vascular event lower in brief supportive psychotherapy group. There was neutrophil-lymphocytes ratio change better in brief supportive psychotherapy group and significantly in acute coronary syndrome patients without chronic heart failure or coronary arterial disease, also there was psychological symptom (depression) change better in brief supportive psychotherapy and significantly in acute coronary syndrome patients with chronic heart failure or coronary arterial disease.

Official Title
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Influence of Brief Supportive Psychotherapy on Major Adverse Cardiovascular Events, Neutrophil-lymphocytes Ratio and Psychological Symptoms in Acute Coronary Syndrome Patients in Intensive Cardiac Care Unit

Conditions
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Acute Coronary Syndrome, Brief Supportive Psychotherapy, Intensive Cardiac Care Unit

Intervention / Treatment
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* Other: Intervention group


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: acute coronary syndrome 》 18 years old have got pharmacological treatment in cardiology standard with or without anxiolytic drug and had got or had not yet got PCI be able to communicate and ready to have interview, fill the questioners and psychotherapy Exclusion Criteria: stroke cardiogenic shock at admission time psychosis reject to involve in study

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Two groups Acute coronary syndrome group who got brief psychotherapy in five session in 5 days.. 30 minutes in 1 session Acute coronary syndrome group who did not get brief supportive psychotherapy as control Double opened RCT
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Influence on brief supportive psychotherapy<br>Intervention group | Other: Intervention group<br>* Brief supportive psychotherapy<br>* Other names: Control group;|
| Active Comparator: Influence of brief supportive psychotherapy<br>Control group | Other: Intervention group<br>* Brief supportive psychotherapy<br>* Other names: Control group;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Major adverse cardiovascular events | Fatal arrhytmia, recurrent myocardial infarction, cardiogenic shock, death | 5 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Neutrophil-lymphocytes ratio | Pre-post measure | 5 days | 
| Psychological symptoms (Hospital anxiety depression scale) | Pre-post measure | 5 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Brief supportive psychotherapy, acute coronary syndrome, major adverse cardiovascular events, neutrophil-lymphocytes ratio, psychological symptoms