The Effect of Physical Training and the Omega 3 Consumption on Attention Deficit Hyperactivity Disorder in Children

Study Overview
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Brief Summary
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The attention deficit hyperactivity disorder (ADHD) usually occurs in preschool and may cause disabilities through whole life.

Detailed Description
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The attention deficit hyperactivity disorder (ADHD) usually occurs in preschool and may cause disabilities through whole life. The treatment of this disease is expensive and difficult. Moreover, physical exercise and omegas consumption may improve the cognitive functions and behavior, so it could be an interesting strategy to improve this disorder. The aim of the present study is to verify the effects of multiple components physical training and the consumption of omega 3 on behavior, cognitive functions and the serum levels of BDNF and IGF-1 in ADHD children. Thus, 68 ADHD children, between seven and fourteen years old will be selected. The volunteers will be randomly divided into four groups: Physical Training Group (PTG), Omega Group (OG), Omega and Physical Training Group (OPTG) and Control Group (CG). The protocol of the experiment will last three months in which the OPTG will make physical training and receive fish oil capsules, and the PTG will make only the physical training and receive a placebo of fish oil. The others groups will be oriented not to make any type of physical training, but the OG will receive fish oil capsule, and the CG will receive a placebo of fish oil. Behavioral and cognitive functions evaluations and blood analysis will be made at the beginning and at the end of the protocol.

Official Title
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The Effect of Physical Training and the Omega 3 Consumption on Attention Deficit

Conditions
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Attention Deficit Hyperactivity Disorder

Intervention / Treatment
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* Dietary Supplement: Omega 3
* Other: Physical Training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Children with ADHD: male, between seven and fourteen years old, sedentary, studing in a regular school. Exclusion Criteria: Taking psychoactive medications, taking omega supplement.

Ages Eligible for Study
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Minimum Age: 7 Years
Maximum Age: 14 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Physical Training<br>The training group will make physical exercise for three months (three times a week). | Dietary Supplement: Omega 3<br>* Capsules of omega 3, 1000mg / capsules. Administered 3 times a day.<br>|
| Other: Sedentary<br>The sedentary group will be oriented not to make any type of physical training for three months. | Dietary Supplement: Omega 3<br>* Capsules of omega 3, 1000mg / capsules. Administered 3 times a day.<br>|
| Placebo Comparator: Placebo<br>The omega 3 group will receive 2g per day of mineral oil during 90 days treatment | Other: Physical Training<br> <br> |
| Experimental: Omega 3<br>The omega 3 group will receive 2g per day of fish oil during 90 days treatment | Other: Physical Training<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Conners Scale | Scores on the Conners scale. Scores above 60 indicate ADHD. Minimum 0 and a maximum of 126. | 3 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Physical Training, ADHD-Attention deficit hyperactivity disorder, Omega 3