The Weekend Effect and Its Possible Influence on the Prognosis of Patients With Non-varicose Upper Gastrointestinal Bleeding

Study Overview
=================
Brief Summary
-----------------
The hypothesis is that the mortality of patients with non-varicose upper gastrointestinal bleeding after performing early gastroscopy who are admitted on weekends and night hours is higher than those admitted on weekdays or during daytime hours.

Detailed Description
-----------------
The aim of the study is to evaluate the impact of the schedule (day or night) and the day of admission (working or weekend / night) on the mortality of patients with non-varicose upper gastrointestinal bleeding after performing an early gastroscopy. A retrospective observational study will be carried out in patients admitted to the bleeding unit of the Santa Creu I Sant Pau Hospital, where we observed hospital mortality and 30 days after performing an early gastroscopy, the duration of admission, signs of hemorrhagic activity in a period of less than 12 h. After early gastroscopy and types of endoscopic treatments, data will be collected by reviewing medical records. The number of patients expected to be included in this study is 1320 patients. Patients will be included the day they enter the bleeding unit for an early gastroscopy.

Official Title
-----------------
Observational Study About the Weekend Effect and Its Possible Influence on the Prognosis of Patients With Non-varicose Gastrointestinal Bleeding

Conditions
-----------------
Acute Upper Gastrointestinal Hemorrhage

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion criteria: Patients older than 18 years. Patients admitted to the Bleeding Unit with a diagnosis of upper gastrointestinal bleeding. Patients who have undergone an early endoscopy to determine the source of bleeding. In case of readmissions during the study period, we consider only the admission closest to his death or discharge. Exclusion criteria: Patients diagnosed with gastrointestinal bleeding varicose. Patients who present with gastrointestinal bleeding and did not perform early gastroscopy (during the first 24 hours) Patients admitted for different medical conditions, who developed upper gastrointestinal bleeding during the course of hospital stay.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mortality | In-hospital mortality and at 30 days after early gastroscopy will be assessed through clinical history observation, within the study period | During the years 2017 and 2018 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Entry Duration | The time between admission and discharge | During the years 2017 and 2018 | 
| Signs of bleeding activity in a period of less than 12 h. post gastroscopy early. | It will be evaluated using the Rockall scale | During the years 2017 and 2018 | 
| Type of endoscopic treatments | Hemostasis can be performed by applying different techniques or a combination of them | During the years 2017 and 2018 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Weekend effect, non-varicose upper gastrointestinal bleeding