Ridge Preservation In Mandibular Molars Using Mixture Of ABB And Autogenous Particulate VS Sticky Bone

Study Overview
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Brief Summary
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Histological Measurement Comparing the density of the new bone formed during socket preservation technique using a Mixture of Anorganic Bovine Bone(ABB) And Autogenous Particulate vs a Mixture of Injectable Platelets Rich Fibers, ABB And Autogenous Particulates (sticky bone). radiographical measurements of the amount of bone dimensions changes in socket preservation technique in 6-month period using a Mixture Of Anorganic Bovine Bone(ABB) And Autogenous Particulate vs a Mixture Of Injectable Platelets Rich Fibers, ABB And Autogenous Particulates (sticky bone)

Official Title
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Alveolar Ridge Preservation In Mandibular Molars Using Mixture Of Anorganic Bovine Bone(ABB) And Autogenous Particulate VS Mixture Of Injectable Platelets Rich Fibrin, ABB And Autogenous Particulates (Sticky Bone).

Conditions
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Alveolar Bone Loss, Bone Graft Failure, Alveolar Bone Resorption

Intervention / Treatment
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* Procedure: ABB And Autogenous Particulate
* Procedure: PRF, ABB & Autogenous Particulate


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adult patients with hopeless mandibular molars indicated for extraction and implant placement in two stages that indicate socket preservation. Both sexes. No intraoral soft and hard tissue pathology. No systemic condition that contraindicate implant placement. Exclusion Criteria: Presence of fenestrations or dehiscence of the residual bony Walls after extraction. Heavy smokers more than 20 cigarettes per day .(24) Patients with systemic disease that may affect normal healing. Psychiatric problems Disorders to implant are related to history of radiation therapy to the head and neck neoplasia, or bone augmentation to implant site. Patients that refuse to be called back for implant placement post extraction. Patients that have exceeded bone resorption surrounding the tooth prior to extraction and require guided bone regeneration.

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: PRF , ABB & Autogenous Particulate<br>Platelets rich fibrin + anorganic bovine bone + autogenous particulate graft | Procedure: PRF, ABB & Autogenous Particulate<br>* adding an injectable platelets rich fibrin to a Mixture of autogenous bone graft aquired at the time of surgery with a 50:50 ration of anorganic bovine bone and filling the socket<br>|
| Active Comparator: ABB And Autogenous Particulate<br>anorganic bovine bone +autogenous particulate graft | Procedure: ABB And Autogenous Particulate<br>* Mixing the autogenous bone graft aquired at the time of surgery with a 50:50 ration of anorganic bovine bone and filling the socket<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| histomorphometrical bone quality | histological bone quality measured from a core sample taken from the grafted site | 6 month | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| marginal bone loss | alveolar margin bone loss measured be CBCT | 6 month |