Demographics and Clinical Characteristics of Paediatric Intraocular Inflammation in Singapore

Study Overview
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Brief Summary
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Data on demographics, etiology, clinical features, diagnosis, secondary complications, treatment and outcomes of intraocular inflammation in children aged 16 years and below that presented to uveitis clinic in Singapore National Eye Centre (SNEC) from January 1989 to January 2017, will be retrieved and analyzed from the uveitis database retrospectively. The results will be compared with other published studies on different study populations.

Detailed Description
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Data on demographics, etiology, clinical features, secondary complications, treatment and outcomes of intraocular inflammation in children aged 16 years and below that presented to uveitis clinic in Singapore National Eye Centre (SNEC) from January 1989 to January 2017, will be retrieved from the uveitis database retrospectively. Data on demographics, etiology, clinical features, diagnosis, secondary complications, treatment and outcomes will be analyzed using statistical software. The results will be compared with other published studies on different study populations. The results of this study will lead to an improved clinical practice with better treatment selections and an optimised monitoring protocol for follow up care for our paediatric patients with intraocular inflammation. This will lead to better clinical outcomes and prevention of serious sight threatening complications.

Official Title
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Demographics and Clinical Characteristics of Paediatric Intraocular Inflammation in Singapore

Conditions
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Intraocular Inflammation in Children

Intervention / Treatment
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* Other: No intervention. A retrospective case review


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Children aged 16 years and below Clinical diagnosis of intraocular inflammation Exclusion Criteria: •Children with ocular conditions other than intraocular inflammation.

Ages Eligible for Study
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Minimum Age: 1 Day
Maximum Age: 16 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Children with intraocular inflammation<br>All children diagnosed with intraocular inflammation at Singapore National Eye center from from January 1989 to January 2017. | Other: No intervention. A retrospective case review<br>* No intervention. A retrospective case review on demographics, etiology, clinical features, diagnosis, secondary complications, treatment and outcomes of intraocular inflammation in children aged 16 years and below that presented to uveitis clinic in Singapore National Eye Centre from January 1989 to January 2017.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Demographics and clinical characteristics of pediatric intraocular inflammation | percentage of ethnic distribution, percentage of age distribution, percentage of etiology, percentage of clinical features, percentage of diagnosis, percentage of secondary complications, percentage of treatment, percentage of outcomes | January 1989 to January 2017 |