Aerosol Generation in Dental Clinics

Study Overview
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Brief Summary
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The study examines 4 different methods to reduce dental bioaerosol spread in orthodontic procedures.

Detailed Description
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We aim to examine 4 different methods to reduce dental aerosol spread during orthodontic procedures. These methods are: 1) high-volume evacuator, 2) high-volume evacuator and saliva ejector 3) Local Exhaust System 4) disinfection with povidone-iodine nasal swabs and chlorhexidine mouthwash.

Official Title
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Mitigating Effect of Bioaerosols During Orthodontic Procedures: A Randomized Controlled Trial

Conditions
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Risk Reduction, Occupational Exposure, Dentist-Patient Transmission

Intervention / Treatment
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* Other: Chlorhexidine mouthwash and Povidone-Iodine
* Device: High volume evacuator
* Device: High volume evactuator and saliva ejector
* Device: Local Exhaust System


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Orthodontic debonding being performed Acceptance to participate in the study and provide required saliva and nasal samples Exclusion Criteria: Refusal to participate Refusal to provide saliva/nasal swab samples Allergy to Chlorhexidine gluconate Allergy to Povidone-Iodine
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Orthodontic debonding<br> | Other: Chlorhexidine mouthwash and Povidone-Iodine<br>* Chlorhexidine mouth rinse which participants use for 20 seconds before procedure. Moreover, Povidone-Iodine nasal swabs are used to disinfect nostrils<br>Device: High volume evacuator<br>* High volume evacuator held by assistant to capture dental spray<br>Device: High volume evactuator and saliva ejector<br>* High volume evacuator and saliva ejector held by assistant to capture dental spray<br>Device: Local Exhaust System<br>* Local exhaust system hovers above patient head to capture dental spray<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Particle concentration measurements across the 4 different types of interventions |  | During procedure | 
| Mass concentration measurements across the 4 different types of interventions |  | During procedure | 
| Bioaerosol measurement from the tracked sources | Sources include patient, operator and assistant saliva and nasal secretions, preprocedural ambient air, dental unit waterline | During procedure | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bacterial contamination on the inside surface of the mask of operators and assistants | Sources include patient, operator and assistant saliva and nasal secretions, preprocedural ambient air, dental unit waterline | During procedure | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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aerosol, bioaerosol, dentistry, orthodontics, saliva, nose