Alcohol and Tobacco Consumption in Patients With Head and Neck or Lung Cancer

Study Overview
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Brief Summary
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This is an multicenter study for preventive and therapeutic strategies for patients with head and neck cancer

Detailed Description
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Continuing the chronic intoxication by either tobacco or alcohol after the initial diagnosis of a first lung or head and neck cancer significantly improves the risk of experiencing a second cancer, and largely affects the long term survival. Addiction intervention programs should be personalized according to the patient's profile, with the aim to develop more sustained intervention and monitoring in patients identified at higher risk of not spontaneously stopping harmful substance use. As of today, the trajectories of smoking and drinking habits and the risk factors for persisting smoking or drinking habits have been insufficiently explored among patients with a first lung or head and neck cancer. The ALTAK study aims to depict the rate of tobacco smokers 12 months after the initial diagnosis of a first lung or head and neck cancer. The secondary objectives of the study are: to depict the rate of alcohol users 12 months after the initial diagnosis of a H&N cancer to depict the rate of tobacco smokers at cancer diagnosis to depict the rate of alcohol users at cancer diagnosis to determine the social, motivational, psychiatric, tobacco-related, alcohol-related, and cannabis-related features associated with stopping tobacco in the year following the diagnosis of a first TARC. to determine the social, psychiatric, tobacco-related, alcohol-related, and cannabis-related features associated with stopping alcohol drinking in the year following the diagnosis of a first H&N cancer

Official Title
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Prevalence and Risk Factors for Persistent Tobacco or Alcohol Use Over the First Year of a First Lung or Head and Neck Cancer

Conditions
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Head and Neck Cancer, Lung Cancer

Intervention / Treatment
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* Behavioral: physician assessment


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: first head and neck or lung cancer first support age ≥ 18 patient covered by health insurance signed informed consent Exclusion Criteria: prior lung or head and neck cancer History of another cancer <5 years, not evolutive and untreated at baseline (carcinoma of the cervix, or basal cell carcinoma of the skin properly treated are allowed). The presence of a second discovery tumor location at the same time as the lung or head and neck cancer, is not a criteria for non-inclusion mesothelioma and oesophageal cancer unable to undergo trail medical follow up (geographical, social and psychological reasons) pregnant or nursing women patient under guardianship

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| head and neck or lung cancer<br>patient with a first head and neck cancer or first lung cancer | Behavioral: physician assessment<br>* Socio-economic conditions and general features: educational level, professional status... Assessment of current and past use of tobacco: current smoking status reported by the patient; in lifelong non-smokers: previous history of passive smoking reported by the patient; breath carbon monoxide level; in past smokers: age of first cigarette, total reported duration of active smoking, breath carbon monoxide level... in current smokers: age of first tobacco use, total reported duration of active smoking; Fagerström Nicotine Dependence Test... Assessment of the current and past uses of alcohol: previous-year assessment using the CAGE questionnaire and the AUDIT Test; average weekly alcohol consumption over the last 12 months... Assessment of current use of cannabis using the Cannabis Abuse Screening Test Psychiatric assessment using the MINI 5.0<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| tobacco consumption | reported tobacco smoking | at 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| tobacco smoking | frequency tobacco consumption | at baseline, 3 and 6 months | 
| alcohol drinking | frequency of alcohol consumption | at baseline, 3, 6 and 12 months | 
| progression free survival | median time between date of inclusion and date of first progression | at 12 months | 
| overall survival | median time between date of inclusion and date of death | at 12 months | 
| sociodemographic, cancer-related, tobacco-related, alcohol-related, and psychiatric characteristics |  | at baseline | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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lung cancer, head and neck cancer, tobacco use disorder, alcoholism