Lung Ultrasound Score in Covid 19 Infectious Disease in Critical Care (LUS-COVID19)

Study Overview
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Brief Summary
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It might be necessary with Sars-Cov2 pneumopathy patient to repeat thoracic images, the tomodensitometry ones in particular. This task is difficult and nearly impossible for several reasons: respiratory and hemodynamic unstable patient, prone position and due to the high contagious nature of the disease. The lung ultrasound is an easy tool, fast (between 5 and 10 minutes) and as a limited training. In the context of the Sars-Cov2 epidemic, Buonsenso and al case report depict the first lung ultrasound for a Covid 19 patient. Peng and al in Intensive Care Medicine accentuate the usefulness of this particular technic. In the American Journal of Respiratory and Critical Care Medicine, a study has been published as a point-of-care, in which the doctors reported using the lung ultrasound with intensive and critical care patient. In Critical Care 2016, it has been showed that ultrasound allowed with neat precisions, to predict severe ARDS patient response to the prone position, all-cause. Another researchers team found a good correlation between lung ultrasound, the SOFA, APACHE II, CPIS score, and patient mortality. And a new applicability in the pulmonary recruitment by PEEP titration has been presented. The aim of this study is to evaluate the lung ultrasound in Covid19 ARDS.

Official Title
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Lung Ultrasound Score in Covid 19 Infectious Disease in Critical Care

Conditions
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COVID

Intervention / Treatment
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* Procedure: lung ultrasound (LUS)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Diagnosed Sars-Cov2 patient, with PCR method qualitative or quantitative as usual. Intensive or critical care admission ARDS with PaO2/FiO2 <300 at the admission Ventilatory support or oxygen-therapy Exclusion Criteria: Age < 18 years-old Pregnancy Patient with tutor- or curatorship or in prison

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 95 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients with Covid-19 and admitted in critical care unit<br> | Procedure: lung ultrasound (LUS)<br>* Patients with Covid-19 Disease and admitted in critical care unit will be performed a LUS<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| LUS applicability with COVID 19 | In dorsal position, or in prone position, the two hemithorax will be subdivided in 6 parts, and a score will be attributed with the following criteria : A-Lines (0 point), > 3 B-lines (1 point), B-Lines coalscent (2 points), and pulmonary consolidation (3 points). For the echography we can use a convexe sonde, or a cardiac sonde. | 10 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Radiographic correlation (chest Xray and tomodensitometry) | Comparison between Xray / CT scan exam and LUS | 10 months | 
| LUS Mortality prediction | according to LUS score, ventilatory mode and parameters, medical history and bood analysis results | 10 months | 
| Prediction of Prone position response | comparison of LUS score depending of the position used for performing LUS | 10 months |