Validation of COVILUS Score in Patients Suspected of COVID-19 Infection in the Emergency Room

Study Overview
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Brief Summary
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Covid-19 (English acronym meaning coronavirus disease 2019) is an emerging infectious disease caused by a strain of coronavirus called SARS-CoV-2. The current pandemic has resulted in a significant number of admissions in the emergency room (ER) due to suspicion of COVID-19 infection. Use of lung ultrasound is standard practice to diagnose acute respiratory failure in ER. Recently, typical lung ultrasonographic characteristics of COVID-19 disease has been described. The investigators demonstrated that the association of 4 signs in pulmonary ultrasound associated with a clinical sign (COVILUS score) could predict the occurrence of a positive RT-PCR in patients suspected of COVID-19 infection admitted to the emergency room. The investigators are going to conduct a new study to validate this COVILUS score in this type of patient. The main objective will be to validate the diagnostic performance of lung ultrasound in patients admitted to the emergency room with suspected COVID19 infection.

Official Title
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Validation of COVILUS Score in Patients Suspected of COVID-19 Infection in the Emergency Room

Conditions
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Covid19, Lung Ultrasound, Respiratory Complication

Intervention / Treatment
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* Diagnostic Test: Covid19 RT-PCR
* Other: lung ultrasound


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients admitted to ER for suspicion of COVID-19 infection who has a SARS-CoV-2 RT-PCR test and for whom the emergency doctor decide to perform a lung ultrasound as part of the BLUE protocol Age> 18 years old Exclusion Criteria: patients < 18 years of age patients under guardianship or curators pregnancy poor echogenicity due to the presence of an acoustic barrier (pneumothorax, subcutaneous emphysema, etc.) patients with a suspected or proven acute lung disease (pneumonitis, acute respiratory distress syndrome (ARDS)) patients with chronic interstitial lung disease patients who will refuse to give their consent.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: Covid19 RT-PCR|patients admitted to ER for suspicion of COVID-19 infection will have a SARS-CoV-2 RT-PCR test|
|Other: lung ultrasound|patients admitted to ER for suspicion of COVID-19 infection who has a SARS-CoV-2 RT-PCR test and for whom the emergency doctor decide to perform a lung ultrasound|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| concordance between Covid19 RT-PCR results and lung ultrasound results |  | one week | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Covid19, lung ultrasound, Respiratory Complication, triage