Study of Standard Maintenance Method of Intravenous Port and Post-operation Pain Analysis

Study Overview
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Brief Summary
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Investigators deconstructed the port that removed from patients and identified there were structural weakness, old blood clot and fibrin deposits. Investigators consider the problem may be exist in maintenance. After thoroughly examination the maintenance protocol, Investigators identified the problem and try to remodel the maintenance protocol. The Goal of this study was to testify the clinical value of standard maintenance protocol.

Detailed Description
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A secure and easily feasible vascular access is crucial for oncology patients because of the therapeutic need. Although intravenous port has been utilized for 3 decades, catheter-related complication still remain and had to deal with. According to investigators clinical experience, investigators summarized a standard algorithm as a recommendation for intravenous sport implantation. The complication before and after standard algorithm was 20 % and 3.5 %, respectively. However, catheter related infection and malfunction still could not be avoided. If patient was identified with these 2 complications, re-intervention is needed and cancer-related therapy has to be postpone. Investigators deconstructed the port that removed from patients and identified there were structural weakness, old blood clot and fibrin deposits. Investigators consider the problem may be exist in maintenance. After thoroughly examination the maintenance protocol, investigators identified the problem and try to remodel the maintenance protocol. The Goal of this study was to testify the clinical value of standard maintenance protocol.

Official Title
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Study of Standard Maintenance Method of Intravenous Port and Post-operation Pain Analysis

Conditions
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Cancer

Intervention / Treatment
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* Other: normal saline
* Other: normal saline+heparin


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Volunteer with new Port-A inserted Exclusion Criteria: No

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Cancer patients in need of chemotherapy Newly accepted Port-A Implant port maintenance:Catheter irrigation with 20 ml N/S,10 ml N/S sealing tube
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: experimental group<br>use Normal saline | Other: normal saline<br>* experimental group use normal saline sealing tube<br>|
| Active Comparator: comparator group<br>use Heparin | Other: normal saline+heparin<br>* normal saline+heparin(Currently, Regular used in hospital)<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Port- A Catheter complication | In the case of catheter-related complications, a complete biochemical and blood test will be performed on the patient. Will be tested for possible clotting factors, inflammatory index including CRP; procalcitonin; CBC / DC; PT / aPTT /Protein C/ protein S | 1 year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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intravenous port, port maintenancem