Changes of Intra Abdominal Pressure During Surgeries in Prone Position as a Marker of Renal Damage

Study Overview
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Brief Summary
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Background: Patients undergoing surgical operations in prone position do not have a measure of intra abdominal pressure as a standard procedure. Many of them could have elevated values of this parameter and could be exposed to possible renal damage due to a stiffening of the abdominal muscles while being positioned prone. Purpose of study: Intraoperative intrabdominal pressure measurement and evaluation of correlation with possible postsurgical complications. Methodology: Electronic device able to measure intra abdominal pressure is connected between a Foley catheter and a urinary collecting bag. During the procedure, values of the intra abdominal pressure are displayed on a monitor next to anaesthetic machine in real time. The numbers representing the pressure in mmHG are assessed and recorded. Discussion: Possible correlation between intra abdominal hypertension and postsurgical complications in patients operated in prone position could be a foundation to further clinical trials and presurgical assessment of intraabdominal pressure.

Official Title
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Intraoperative Abdominal Pressure Measurement in Patients Undergoing Spine Surgeries in Prone Position as a Marker of Renal Damage

Conditions
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Intraabdominal Hypertension, Prone Postion, Spine Surgery

Intervention / Treatment
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* Device: Intra abdominal pressure measurement


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Consent to participate in the study Patients qualified for surgical stabilization of the spine in prone position Exclusion Criteria: No consent to participate in the study or inability to obtain consent The inability to insert a urinary catheter No indication for urinary catheter Patients undergoing palliative treatment Patients with advanced liver and kidney disease

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients for spine surgery in prone position<br> | Device: Intra abdominal pressure measurement<br>* Device: Biometrix - Intraabdominal pressure monitoring set Intraabdominal pressure monitoring with the intended set in values of milimeters of mercury (mmHg) in real time.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Increase in intra abdominal pressure during surgery. | Change in intra abdominal pressure during surgery in prone position. | Intraoperative | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Correlation of increased abdominal pressure with renal dysfunction assessed by creatinine. | Assessment of renal function in labolatory tests: creatinine change (mg/dl). | From start to eight hours after the surgery. | 
| Correlation of increased abdominal pressure with renal dysfunction assessed by urea. | Assessment of renal function in labolatory tests: urea change (mg/dl). | From start of surgery to eight hours after the surgery. | 
| Correlation of increased abdominal pressure with renal dysfunction assessed by potassium. | Assessment of renal function in labolatory tests: potassium change (mg/dl). | From start of surgery to eight hours after the surgery. | 
| Correlation of increased abdominal pressure with mioglobin. | Assessment in labolatory tests: mioglobin change (mg/dl). | From start of surgery to eight hours after the surgery. |