Effect of Extraction Versus Non-extraction Orthodontic Treatment on the Third Molars

Study Overview
=================
Brief Summary
-----------------
What is the effect of extraction orthodontic treatment in comparison to non- extraction treatment on the position, inclination and incidence of impaction of the third molars?

Detailed Description
-----------------
Data regarding the personal information (name, age and gender), chief complaint, medical and dental history will be taken. Medical history questionnaire will be filled by the patient to exclude the presence of any systemic conditions. complete set of orthodontic records will be taken; Pre- operative records including (standardized intra- and extra-oral photographs, primary impression for study model, panoramic & lateral cephalogram). After formulating the best treatment plan for each patient, All patients will be enrolled into one of two groups: Intervention Group (I) : Extraction treatment group. Comparator group (C): Non-extraction group. Following the end of treatment, Post-treatment records including (standardized intra- and extra-oral photographs, primary impression for study model, panoramic & lateral cephalogram) will be taken. Primary outcome: The angulation of the mandibular third molars.Secondary outcomes: space available for the upper and lower third molar. Angulation of the third molar. The vertical position of the third molars. the mineralization status of the third molars

Official Title
-----------------
Effect of Extraction Versus Non-extraction Orthodontic Treatment on the Third Molars: A Non-Randomized Clinical Trial /a Prospective Clinical Trial

Conditions
-----------------
Orthodontic Treatment Via Premolar Extraction

Intervention / Treatment
-----------------
* Procedure: extraction orthodontic treatment plan


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Adolescent males and females (14-18 years) with Bilaterally unerupted developing third molars. Not more than two thirds of the root development of the third molars had taken place. Dental Class I malocclusion cases requiring four premolar extraction with a moderate anchorage requirement. low or increased vertical dimension. Exclusion Criteria: Premolar extraction cases requiring maximum anchorage preparation. Low vertical dimension. patients without dentofacial deformities, severe facial asymmetries, or missing teeth.

Ages Eligible for Study
-----------------
Minimum Age: 14 Years
Maximum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: extraction treatment<br>patients will be referred for extraction of the upper and lower first premolars to relieve the crowding. | Procedure: extraction orthodontic treatment plan<br>* patients will be referred for extraction of the upper and lower first premolars then orthodontic treatment will follow.<br>|
| No Intervention: non-extraction treatment<br>Leveling and alignment of the moderate crowding will be performed through a recall visits of 4 weeks for wire activation. inter-proximal reduction step might be done if needed. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| third molar angulation | The angulation of the mandibular third molars | at the end of orthodontic treatment | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| space available for the upper and lower third molar | space available for the upper and lower third molar | at the end of orthodontic treatment | 
| Angulation of the third molar. | Angulation of the third molar. | at the end of orthodontic treatment | 
| The vertical position of the third molars | The vertical position of the third molars | at the end of orthodontic treatment | 
| the mineralization status of the third molars | the mineralization status of the third molars | at the end of orthodontic treatment | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
third molar impaction, third molar angulation, third molar vertical position