Development and Evaluation of Web-Based Fertility-Related Decision Support for Young Female Cancer Patients

Study Overview
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Brief Summary
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This study aims to develop a patient-centered, user-center, interactive web-based decision aid to support the young women with cancer in making an informed fertility-related decision and further evaluate its efficacy.

Detailed Description
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This study uses mixed-method and involves 2 stages. As following the IPDAS recommendation for developing decision aids, the first sample of 25 young woman survivors with breast, hematology or ovarian cancer, and oncologist, fertility specialists or nurses will be interviewed to assess the fertility-related decision needs from and. The decision aid is then developed further process of evidence synthesis and multidisciplinary external review. After the draft being evaluated for its validity via Think-aloud cognitive interview method, field testing via one-group quasi-experimental design on 90 young women with newly diagnosed breast, hematology or ovarian cancer will be applied to test its outcomes of decision quality, emotional health and fertility concerns.

Official Title
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Development and Evaluation of Web-Based Fertility-Related Decision Support for Young Female Cancer Patients

Conditions
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Infertility, Female, Female Infertility

Intervention / Treatment
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* Behavioral: web-based decision aid


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age between 20 to 44 Have been diagnosed with breast, hematology or ovarian cancer, and will conduct cancer treatment, such as chemotherapy, hormonal or radiation. Willing to take questionnaire via computer and tablet. Ability to answer the questionnaire with functional emotion and cognition. Ability to read newspaper. Had been consulted and advised by Doctor on the ability of fertility, but have not decided to give birth to a baby. Exclusion Criteria: Age below 20 or above 45. Had been diagnosed with stage 4 cancer. Do not require chemotherapy, hormonal or radiation therapy. Not able to read newspaper or do not access the internet.

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 44 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Cancer and Fertility Decision making<br>Cancer and Fertility Decision aid | Behavioral: web-based decision aid<br>* The decision aid is then developed further process of evidence synthesis and multidisciplinary external review.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Decision conflict,decision regret,fertility knowledge,reproductive concerns after cancer,quality of life | Decisional scale | 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Infertility, young female cancer patients, decision aids, fertility concerns