The Effects of Mindfulness-Based Stress Reduction on Attention and Pain-related Symptoms in Chronic Pain Patients

Study Overview
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Brief Summary
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The main purpose of this study is to determine the degree to which Mindfulness-Based Stress Reduction, a group-based psychological therapy that includes mindfulness meditation exercises, reduces depression, anxiety, stress, pain intensity, and interference of pain with daily life among adult chronic pain patients. The second purpose is to examine the role of attention in improving psychological and physical health for chronic pain patients.

Official Title
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The Effects of Mindfulness-Based Stress Reduction on Attention and Pain-related Symptoms in Chronic Pain Patients: A Randomized Controlled Trial

Conditions
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Pain

Intervention / Treatment
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* Behavioral: Mindfulness-Based Stress Reduction


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adult chronic pain patients who are proficient in English Capable of interacting with others in a group setting Capable of working with a computer Exclusion Criteria: Alcohol or drug abuse (past history is acceptable as long as their situation has been stable for at least 3 months) Psychiatric psychosis (patients who have a past history of schizophrenia are eligible as long as they are currently stable) Current major depressive disorder Current severe social phobia At immediate risk for suicide Cerebral lesions or tumors (unless medically and cognitively stable) Neurological disease Medically unstable Cognitively unstable Previously participated in a mindfulness meditation program

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Mindfulness-Based Stress Reduction<br> | Behavioral: Mindfulness-Based Stress Reduction<br>* An 8-week structured group program that was developed to improve psychological and physical symptoms associated with pain. It incorporates a variety of mindfulness meditation exercises including mindful yoga, sitting meditation, and body scan to facilitate attention, acceptance, and awareness of one's experiences.<br>* Other names: MBSR;|
| No Intervention: Waitlist Control<br> | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain disability and Attention | Change in pain disability assessed by the Pain Disability Index (PDI). Change in attention assessed by an adapted version of the Change Blindness Task | Baseline, immediately following treatment, and at 3 months follow up | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Depression | Change in depression assessed by the Depression, Anxiety, and Stress Scale 21 (DASS-21) | Baseline, immediately following treatment, and at 3 months follow up | 
| Anxiety | Change in anxiety assessed by the Depression, Anxiety, and Stress Scale 21 (DASS-21) | Baseline, immediately following treatment, and at 3 months follow up | 
| Stress | Change in stress assessed by the Depression, Anxiety, and Stress Scale 21 (DASS-21) | Baseline, immediately following treatment, and at 3 months follow up | 
| Mindfulness | Change in mindfulness assessed by the Five Facet Mindfulness Questionnaire (FFMQ) and Mindful Attention Awareness Scale (MAAS) | Baseline, immediately following treatment, and at 3 months follow up | 
| Acceptance | Change in acceptance assessed by the Chronic Pain Acceptance Questionnaire (CPAQ) | Baseline, immediately following treatment, and at 3 months follow up | 
| Pain Intensity | Change in pain intensity assessed by the Short-form McGill Pain Questionnaire (SF-MPQ-2). | Baseline, immediately following treatment, and at 3 months follow up | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Meditation, Mindfulness, Attention, Chronic Pain, Depression, Anxiety, Stress, Acceptance, Pain intensity, Pain disability