Reduced Port Laparoscopic Gastrectomy for Gastric Cancer

Study Overview
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Brief Summary
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Reduced port laparoscopic gastrectomy has been adopted in clinical. The safety and outcome of reduced port laparoscopic gastrectomy has not been systematically evaluated. The investigators sought to compare the short and long-term outcome of patients with gastric cancer who underwent reduced port gastrectomy with patients underwent traditional laparoscopic gastrectomy

Detailed Description
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Reduced port laparoscopic gastrectomy has been adopted in clinical. The safety and outcome of reduced port laparoscopic gastrectomy has not been systematically evaluated. The investigators designed a comparative study, which sought to compare the short and long-term outcome of patients with gastric cancer who underwent reduced port gastrectomy with patients underwent traditional laparoscopic gastrectomy. The short-term outcome include surgical complications, postoperative morbidity, postoperative nutrition. The long-term outcome mainly include long-term survival.

Official Title
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Comparison the Short and Long-term Outcome of Patients With Gastric Cancer Who Underwent Reduced Port Laparoscopic Gastrectomy With Patients Underwent Traditional Laparoscopic Gastrectomy

Conditions
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Laparoscopic, Gastrectomy

Intervention / Treatment
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* Procedure: Reduced port laparoscopic gastrectomy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Histologically confirmed adenocarcinoma of the stomach, T1-T4 stages. Eastern Cooperative Oncology Group performance status of 0 or 1. Adequate organ function. Exclusion Criteria: Patients had distant metastasis. oesophageal invasion of more than 3 cm. Borrmann type 4 or large (more than 8 cm) type 3 carcinoma. Previous chemotherapy or radiation therapy for any other malignancies.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 90 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Reduced port laparoscopic gastrectomy<br>The definition of reduced port laparoscopic gastrectomy was 1-3 ports used in laparoscopic gastrectomy for gastric cancer. | Procedure: Reduced port laparoscopic gastrectomy<br>* The ports were reduced in the surgery of intervention arm.<br>|
| No Intervention: Standard laparoscopic gastrectomy<br>5 ports were used in standard laparoscopic gastrectomy | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 5-year survival rate | Longterm survival for patients with gastrectomy after reduced port laparoscopic gastrectomy | 5 years | 
| 3-year survival rate | Survival rate for patients with gastrectomy after reduced port laparoscopic gastrectomy | 3 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative morbidity rate | Postoperative morbidity rate for patients with gastrectomy after reduced port laparoscopic gastrectomy | 6 months | 
| Malnutrition rate | Malnutrition rate for patients with gastrectomy after reduced port | 6 months | 
| Quality of life in PGSAS-45 scale | The quality of life were assessed using PGSAS-45 scale for patients with gastrectomy after reduced port laparoscopic gastrectomy. | 12 months |