Digestive Tract Reconstruction After Gastrectomy of Gastric Cancer With Type 2 Diabetes

Study Overview
=================
Brief Summary
-----------------
Different digestive tract reconstruction will affect the blood glucose level of gastric cancer with type 2 diabetes. Subtotal gastrectomy with Billroth II reconstruction and total gastrectomy with Roux-en-Y reconstruction may help to improve glycaemic control which includes fasting blood glucose, postprandial blood glucose, glycosylated hemoglobin, C -peptide and body weight of gastric cancer patients with type 2 diabetes.

Detailed Description
-----------------
Different digestive tract reconstruction will affect the blood glucose level of gastric cancer with type 2 diabetes. Subtotal gastrectomy with Billroth II reconstruction and total gastrectomy with Roux-en-Y reconstruction may help to improve glycaemic control which includes fasting blood glucose, postprandial blood glucose, glycosylated hemoglobin, C -peptide and body weight of gastric cancer patients with type 2 diabetes. The investigators will observed fasting blood glucose, postprandial blood glucose, glycosylated hemoglobin, C -peptide and body weight of the patients preoperation, 14 days postoperation 3 month and 6month postoperation. The investigators will observed the effect of blood glucose to different digestive tract reconstruction after gastrectomy of gastric cancer with type 2 diabetes

Official Title
-----------------
The Effect of Blood Glucose to Different Digestive Tract Reconstruction After Gastrectomy of Gastric Cancer With Type 2 Diabetes

Conditions
-----------------
Gastric Cancer

Intervention / Treatment
-----------------
* Procedure: digestive tract reconstruction


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 18-75 years old,gastric cancer ,can be performed operation with type 2 diabetes,fasting blood glucose > 6.1mmol/L without serious underlying diseases which may affect the metabolism and nutrient uptake without serious underlying diseases which may affect anesthesia and operation can be performed subtotal or total gastrectomy, predicted survival period > 6months no other abdominal operation preoperation consultation informed consent Exclusion Criteria: recurrent,metastasis or die patient requests for quit pregnancy

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Subtotal gastrectomy , BillrothⅠ<br> | Procedure: digestive tract reconstruction<br>* Subtotal gastrectomy with BillrothⅠ or BillrothⅡ, total gastrectomy with jejunal interposition or Roux-en-Y reconstruction<br>* Other names: no other names;|
| Subtotal gastrectomy , BillrothⅡ<br> | Procedure: digestive tract reconstruction<br>* Subtotal gastrectomy with BillrothⅠ or BillrothⅡ, total gastrectomy with jejunal interposition or Roux-en-Y reconstruction<br>* Other names: no other names;|
| total gastrectomy, jejunal interposition<br> | Procedure: digestive tract reconstruction<br>* Subtotal gastrectomy with BillrothⅠ or BillrothⅡ, total gastrectomy with jejunal interposition or Roux-en-Y reconstruction<br>* Other names: no other names;|
| total gastrectomy , Roux-en-Y<br> | Procedure: digestive tract reconstruction<br>* Subtotal gastrectomy with BillrothⅠ or BillrothⅡ, total gastrectomy with jejunal interposition or Roux-en-Y reconstruction<br>* Other names: no other names;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |