Multisensory Training in PD

Study Overview
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Brief Summary
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People with Parkinson's disease (PD) were characterized by many motor symptoms, including rigidity, postural instability, bradykinesia, and resting tremor. These motor symptoms might cause gait dysfunction. Gait dysfunction represented a common sign of PD, including reduced gait velocity, reduced stride length, reduced arm swing, and increased gait variability. Poor postural control in people with PD might result to increase gait variability and then increase fall risk. Previous studies reported that proprioceptive-vestibular multisensory training improved postural stability in people with PD. However, no literature investigated the effects of proprioceptive-vestibular multisensory training on gait variability. Therefore, the purpose of this study is to examine the effect of proprioceptive-vestibular multisensory training on gait variability in people with PD.

Official Title
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Effect of Multisensory Training on Gait Variability in People With Parkinson's Disease

Conditions
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Parkinson Disease

Intervention / Treatment
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* Other: Multisensory training
* Other: Conventional training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Idiopathic PD Hoehn and Yahr stage I to III Age 60 80 y/o Mini-Mental State Examination (MMSE) ≥24 Ability to ambulate independently (with or without walking aid) Exclusion Criteria: Affecting the peripheral vestibular system Medical condition that substantially influenced their gait and balance performance People had joined any rehabilitation past 1 month

Ages Eligible for Study
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Minimum Age: 50 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Multisensory training group<br>The intervention is a 50-minute session and 2-sessions/week, totaling 6 weeks | Other: Multisensory training<br>* Multisensory training included marching on the foam with visual deprivation and treadmill training with visual deprivation<br>|
| Active Comparator: Conventional training group.<br>The intervention is a 50-minute session and 2-sessions/week, totaling 6 weeks | Other: Conventional training<br>* Conventional training included strengthening, balance training and gait training<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Gait variability | Using GAITRite system to measure coefficient of variation | Change from baseline at 6 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Gait performance | Using the GAITRite system to evaluate saptiotemporal parameters | Change from baseline at 6 weeks | 
| Sensory organization test | Using NeuroCom Smart Balance Master | Change from baseline at 6 weeks | 
| Timed up and go test | To evaluate functional mobility | Change from baseline at 6 weeks | 
| Dynamic Gait Index | To evaluate functional mobility | Change from baseline at 6 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Multisensory training, Gait variability