Lung Volume Change Between Noninvasive Positive Pressure Ventilation by Nasal Pillow and High Flow Nasal Cannula

Study Overview
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Brief Summary
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The difference of lung volume change will be monitored by electrical impedance tomography before and after use of noninvasive positive pressure ventilation by nasal pillow and high flow nasal cannula in post-extubation patients.

Detailed Description
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Electrical impedance tomography can effectively monitor the lung volume change in ICU patients who were under mechanical ventilator or noninvasive positive pressure ventilator support. Continuous positive airway pressure (CPAP) support by nasal pillow and high flow nasal cannula can improve inspiratory function in extubated patients . However, the extent of lung volume change or functional residual volume (FRC) change by using these two devices were never surveyed before in extubated patients. The investigators will check end-expiratory lung volume (EELV) ,anterior, medio-anterior, medio-posterior and posterior EELV by electrical impedance tomography after use of these two devices in extubated patients.

Official Title
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The Difference of Lung Volume Change Detected by Electrical Impedance Tomography (EIT) Between Noninvasive Positive-pressure Ventilation (NIPPV) Support by Nasal Pillow and High Flow Nasal Cannula in Post-extubation Patients

Conditions
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Respiratory Failure

Intervention / Treatment
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* Device: Nasal Pillow CPAP


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: >20 y/o Any extubated patients after tolerating spontaneous breathing trial Exclusion Criteria: Presence of tracheostomy Recent facial trauma Active gastro-intestinal bleeding Do-not-intubate status and Planned use of BiPAP after extubation. Patients with unstable spinal lesions or fractures. BMI> 50 Patients with a cardiac pacemaker Burn injury with skin defect

Ages Eligible for Study
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Minimum Age: 20 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Nasal pillow CPAP<br>Nasal pillow CPAP | Device: Nasal Pillow CPAP<br>* Nasal Pillow CPAP in extubated patients<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| • End-expiratory lung volume (EELV) determined by electrical impedance tomography after high flow nasal cannula and nasal pillow CPAP |  | at day 1 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Anterior, medio-anterior, medio-posterior and posterior EELV at each time |  | at day 1 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Electrical impedance tomography, Nasal Pillow Continuous Positive Airway Pressure(CPAP), High Flow Nasal Cannula, extubation