linjc16/ctgov huggingface dataset:
Early Identification of Suspected Deep Tissue Injury (sDTI)

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to further clarify existing research on the early identification and documentation of suspected deep tissue injury (sDTI). Basic principles of physiology along with prior research suggests that sDTI has quantifiable amounts of heat (or lack thereof) relative to surrounding tissue that will exhibit characteristic thermal signatures (temperature). These signatures will be measured and quantitatively recorded using long-wave infrared thermography (LWIT) to not only identify sDTI, but to also learn more about their pathophysiological evolution. Additionally, the LWIT physiological data will be cross-compared to the gold standard of visual assessment and other current standards of wound evaluation.

Official Title
-----------------
Early Identification of Suspected Deep Tissue Injury (sDTI) Utilizing Long-Wave Thermographic Imaging (LWIT)

Conditions
-----------------
Pressure Ulcer, Bed Sore

Intervention / Treatment
-----------------
* Other: No Intervention


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 18 years of age or older Can tolerate position changes ≥ 10 minutes Non-pregnant Exclusion Criteria: Therapies/treatments cannot be safely suspended to for an imaging session Non-English speaking

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Tissue w/ Thermographic Anomaly<br>Visibly undamaged tissue with anomaly identified by the thermographic image No intervention Standard of care | Other: No Intervention<br>* Standard of Care Only<br>|
| Tissue w/o Thermographic Anomaly<br>Visibly undamaged tissue with no anomaly identified by the thermographic image No intervention Standard of care | Other: No Intervention<br>* Standard of Care Only<br>|
| Tissue w/ Visible Anomaly<br>Visibly damaged tissue No intervention Standard of care | Other: No Intervention<br>* Standard of Care Only<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of anatomical areas with intact skin and a thermographic anomaly that progress to a stageable pressure ulcer | Sensitivity and specificity of a thermographic anomaly that progresses to a stageable pressure ulcer | Up to 25 days | 
| Number of anatomical areas with intact skin and a thermographic anomaly that do not progress to a stageable pressure ulcer | Sensitivity and specificity of a thermographic anomaly that does not progress to a stageable pressure ulcer | Up to 25 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Temperature change associated with anatomical areas after a stageable pressure ulcer occurs |  | Up to 25 days |
Electronic Alert for Acute Kidney Injury in Geriatric Wards

Study Overview
=================
Brief Summary
-----------------
Operating acute kidney injury electronic alert in geriatric wards; Acute authenticity evaluation of acute kidney injury electronic alert; To explore the clinical value of electronic alert for acute kidney injury prevention and treatment in geriatric wards.

Official Title
-----------------
Study on the Application Value of Electronic Alert for Acute Kidney Injury in Geriatric Wards

Conditions
-----------------
Acute Kidney Injury

Intervention / Treatment
-----------------
* Other: electronic alert


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age over 65 years old Diagnose of acute kidney injury by e-alert Exclusion Criteria: Baseline serum creatinine > 4mg/dL Stage-5 chronic kidney disease or maintenance hemodialysis Kidney transplantation Amputation

Ages Eligible for Study
-----------------
Minimum Age: 65 Years
Maximum Age: 100 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Alert group<br> | Other: electronic alert<br>* The e-alert system was developed by the divisions of Nephrology and Information Management of Guangdong Provincial People's Hospital (Patent Application 201610001950.5). The alert system made a diagnosis of acute kidney injury according to Kidney Disease: Improving Global Outcomes criteria. Then, the doctor receives an alert of acute kidney injury.<br>|
| No Intervention: Control group<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Diagnosis rate of acute kidney injury (Rate of missed diagnosis); |  | 1 year | 
| Rate of dialysis |  | 1 year | 
| Rate of death |  | 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rate of nephrology consultation |  | 1 year | 
| Rate of nephrology follow-up |  | 1 year | 
| Renal function after 90 days of acute kidney injury |  | 1 year | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Acute kidney injury, Alert, Geriatric wards
Epidemiology of Diabetes Interventions and Complications (EDIC)

Study Overview
=================
Brief Summary
-----------------
The Diabetes Control and Complications Trial (DCCT,1983-1993) compared intensive therapy aimed at near-normal glycemia versus conventional therapy with no specific glucose targets in 1441 subjects with type 1 diabetes (T1DM) over a mean follow-up of 6.5 years. Intensive therapy reduced the risks of retinopathy, nephropathy, and neuropathy by 35-76%. The level of glycemia was the primary determinant of complications. We also described the adverse effects of intensive therapy; assessed its effects on cardiovascular disease (CVD) risk factors, neurocognition and quality of life; and projected the lifetime health-economic impact. After the primary DCCT results were reported in 1993, intensive therapy aiming for a HbA1c <7% was adopted world-wide as standard-of-care for T1DM. The Epidemiology of Diabetes Interventions and Complications (EDIC, 1994-present) is the observational follow-up study of the DCCT cohort. Micro- and cardio-vascular complications and a wide range of established and putative risk factors, including genetic and epigenetic factors, have been measured with standardized methods, carefully documented and events adjudicated. EDIC has notably shown that the early beneficial effects of intensive versus conventional therapy on complications persisted for  15 years despite the convergence of HbA1c levels in the two groups during EDIC, a novel concept termed metabolic memory. Prior intensive therapy was also shown to reduce substantially the risk of CVD events and mortality. The overarching goals for the current cycle (2022-2027) are to study the occurrence and identify potentially modifiable risk factors of the more advanced microvascular and cardiovascular complications and physical and cognitive dysfunction that are occurring with increasing diabetes duration and age. With increasing longevity, the increased adiposity that has affected patients with T1DM, including EDIC participants, has potential adverse consequences. Thus, the impact of diabetes duration, aging and adiposity on morbidities and their underlying risk factors will be studied. The results will guide treatment priorities as T1DM patients age.

Official Title
-----------------
Epidemiology of Diabetes Interventions and Complications (EDIC)

Conditions
-----------------
Type 1 Diabetes Mellitus

Participation Criteria
=================
Eligibility Criteria
-----------------
Participants originally enrolled in the Diabetes Control and Complications Trial (DCCT) (N01-DK-6-2204-A).

Ages Eligible for Study
-----------------
Minimum Age: 19 Years
Maximum Age: 45 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
The Gaps-in-Noise Test: Gap Detection Thresholds in Normal-Hearing Young Adults

Study Overview
=================
Brief Summary
-----------------
The aim of this study was to establish parameters for the Gaps-in-Noise test in normal-hearing young adults. One hundred subjects (50 males and 50 females) received an audiological evaluation to rule out hearing loss and auditory processing disorder. The Gaps-in-Noise test was then conducted on all subjects. The mean gap detection threshold was 4.19 msec. A psychometric function by gap duration was constructed, revealing that the percentage of correct responses was less than or equal to 5% for a gap duration of 2 msec, 10-30% for a gap duration of 3 msec, 60-70% for a gap duration of 4 msec, and over 96% for gap durations of 5 msec or longer. The results suggest that the data obtained can be applied as reference values for future testing. In the subjects evaluated, the Gaps-in-Noise test proved to be consistent with low variability.

Official Title
-----------------
The Gaps-in-Noise Test: Gap Detection Thresholds in Normal-Hearing Young Adults

Conditions
-----------------
Auditory Perception, Psychoacoustics

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Subject inclusion criteria were: all of the subjects have to have auditory thresholds lower than 20 dB HL at all of the frequencies evaluated (octave frequencies between 0.25 to 8 kHz), bilaterally; type A tympanometric curves with presented ipsilateral and contralateral acoustic reflexes; 95% or higher correct responses for each ear in the dichotic digit test. Subject inclusion criteria also included negative histories for audiologic, otologic, head trauma, and neurologic involvement. Exclusion Criteria: Hearing loss; Auditory processing disorder; Histories of audiologic, otologic, head trauma, and neurologic involvement.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 31 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| 1<br>Normal-hearing adults between 18 and 31 years of age. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| gap detection test |  | half hour | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
GIN test, gap detection, temporal resolution, auditory perception, psychoacoustics
Prepulse Inhibition of Startle in Cocaine Dependence - 7

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to assess the effects of chronic cocaine use on the acoustic startle response and on gating of this response in humans.

Detailed Description
-----------------
The objective of this study is to assess the effects of chronic cocaine use on the acoustic startle response and on gating of this response in humans.

Official Title
-----------------
Prepulse Inhibition of Startle in Cocaine Dependence (Human)

Conditions
-----------------
Cocaine-Related Disorders, Substance-Related Disorders

Intervention / Treatment
-----------------
* Drug: Amantadine


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Cocaine dependence. Male. Right handed. Negative urine for cocaine Exclusion Criteria: Positive urine for cocaine. History of head trauma. Significant medical disease.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 60 Years

Sexes Eligible for Study
-----------------
Male

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Masking: Double


Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: Amantadine|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Percent prepulse inhibition |  |  | 
| Cocaine assessment |  |  | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
cocaine dependence
Ultrasound B Mode Imaging and Elastography

Study Overview
=================
Brief Summary
-----------------
A Pilot Study on Ultrasound B mode Imaging and Elastography during administration of Xiaflex (collagenase clostridium histolyticum) for Dupuytren's contracture.

Detailed Description
-----------------
Ultrasound analysis will be obtained on patient that receives Xiaflex as standard of care for Dupuytren's contracture

Official Title
-----------------
Ultrasound B Mode Imaging and Elastography During Administration of Xiaflex (Collagenase Clostridium Histolyticum) for Dupuytren's Contracture: A Pilot Study (The UBIEX-DC Study)

Conditions
-----------------
Dupuytren's Contractures

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Normal Hand or Hand Dupuytren's contracture Exclusion Criteria: Previous treatment of Dupuytren's cord

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 99 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Normals, Dupuytren's subjects with and without treatment<br>Ultrasound analysis of patient receiving treatment for Dupuytren's | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Ultrasound B mode Imaging and Elastography | A Pilot Study: Ultrasound B mode Imaging and Elastography during administration of Xiaflex | 30 day trial |
Perceived Barriers to Exercise in Individuals Living With Spinal Cord Injury

Study Overview
=================
Brief Summary
-----------------
Purpose: This project is designed to identify what the key barriers to participating in exercise are for the general population of people living with spinal cord injury (SCI) in the United States (US).

Detailed Description
-----------------
Purpose: This project is designed to identify what the key barriers to participating in exercise are for the general population of people living with spinal cord injury (SCI) in the United States (US). Background: A previous study of 681 people living with SCI demonstrated that the majority of participants thought that exercise was important (97%), but that only 57% actually had access to exercise (K.D. Anderson. 2004. Targeting recovery: Priorities of the spinal cord injured population. J. Neurotrauma. 21:1371-1383). The next step in continuing that research is to determine in more detail what the perceived barriers to exercise are so that they can be addressed in multiple settings (research design of exercise protocols, community access and awareness, clinical effectiveness, etc.). Methods: Internet-based survey of people with spinal cord injuries (SCI). Expected Results: It is expected that the perceived barriers will fall under 3 main categories (internal, resources, and structural). However, there may be other barriers we are unaware of, for example, societal or cultural factors or other factors completely unforeseen. Relevance to Rehabilitation: The findings of this project will provide valuable information needed to design strategies aimed at improving participation in exercise by people living with SCI. SCI results in several secondary health conditions over time, which can likely be positively impacted by exercise.

Official Title
-----------------
Perceived Barriers to Exercise in Individuals Living With Spinal Cord Injury.

Conditions
-----------------
Spinal Cord Injury

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Any person with a spinal cord injury who is at least 18 years of age, lives in the United States of America, and can read English. Exclusion Criteria: People who cannot read English will not be included because the website will be hosted in English and the survey software (phpQuestionnaire 2.2 by Chumpsoft, Inc.) default language is English.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| 1<br>Spinal Cord Injury | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Any person with a spinal cord injury, at least 18 years of age
Physical Activity and Immigrant Health

Study Overview
=================
Brief Summary
-----------------
There is today a growing need for culturally adapted initiatives among immigrants to prevent and treat T2D. Others have failed to increase the level of physical activity in this sedate group. The investigators believe this is due to missing assistance and lack of influence from the Pakistani milieu. To improve this, a culturally adapted physical activity will be established in this project in close cooperation with the Pakistanis themselves. Through this program it is the investigators' goal to increase their physical activity level and prevent lifestyle diseases among Pakistanis in Oslo with a high risk of developing these diseases.

Conditions
-----------------
Physical Activity

Intervention / Treatment
-----------------
* Behavioral: Physical activity (PA) and immigrants


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Pakistani background 25-55 year old Physically inactive Exclusion Criteria: Diabetes heart condition medication that could affect the results

Ages Eligible for Study
-----------------
Minimum Age: 25 Years
Maximum Age: 55 Years

Sexes Eligible for Study
-----------------
Male

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: Physical activity (PA) and immigrants|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Physical activity level |  |  | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Activity Level
Is Transcutaneous Carbon Monoxide Saturation of E-cigarette Users Comparable to That of Smokers?

Study Overview
=================
Brief Summary
-----------------
Suspicions of carbon monoxide poisoning that lead to the treatment of victims are numerous. Measurement of transcutaneous carbon monoxide saturation (SpCO) is a useful diagnostic and triage tool for victims and the toxic threshold is clearly defined for both non-smokers (SpCO> 5%) and smokers ( SpCO> 10%). Currently, the use of e-cigarettes is democratizing. Unfortunately, the threshold for toxic SpCO is not defined for this patient profile. The risk is treating in excess or worse than underestimating carbon monoxide poisoning in e-cigarette users who would be exposed to carbon monoxide exposure.

Official Title
-----------------
Is Transcutaneous Carbon Monoxide Saturation of E-cigarette Users Comparable to That of Smokers?

Conditions
-----------------
Carbon Monoxide Poisoning

Intervention / Treatment
-----------------
* Other: Pulse CO-oximetry


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patient presenting to adult emergency department Age ≥ 18 years Exclusion Criteria: Passive exposure to tobacco Mixed exposure (tobacco / e-cigarette) Patient having objected to the processing of his data

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Pulse CO-oximetry<br>Measuring blood Carbon Monoxide levels with Pulse CO-oximetry (SpCO) Measurements are taken with a noninvasive method by placing a sensor on a patient, usually on the fingertip. | Other: Pulse CO-oximetry<br>* Measuring blood Carbon Monoxide levels with Pulse CO-oximetry (SpCO)<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Blood Carbon Monoxide levels measurements | Measuring blood Carbon Monoxide levels with Pulse CO-oximetry (SpCO) | Baseline | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
carbon monoxide poisoning, e-cigarette user, transcutaneous saturation measurements
Evaluation of Osseo-integration After Placement of Dental Implants With Patients Receiving Radiotherapy for Buccopharyngeal Oncology

Study Overview
=================
Brief Summary
-----------------
Follow up of implants with patients receiving radiotherapy for buccopharyngeal oncology. Implants will be placed 6 weeks before start of the radiotherapy or at least 3 months after the end of the radiotherapy

Official Title
-----------------
Evaluation of Osseo-integration After Placement of Dental Implants With Patients Receiving Radiotherapy for Buccopharyngeal Oncology

Conditions
-----------------
Dental Implants

Intervention / Treatment
-----------------
* Procedure: Evaluation of the success rate of implants


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients receiving radiotherapy (6 weeks later or at least 3 months before) for buccopharyngeal oncology

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Evaluation of implants of patients receiving radiotherapy.<br> | Procedure: Evaluation of the success rate of implants<br>* Evaluation of the success rate of implants<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Recovering and ingrowing of dental implants |  | 4 to 6 months | 
| Success rate of dental implants |  | 4 to 6 months |