External Oblique Intercostal Plane Block vs. Transversus Abdominis Plane Block for Laparoscopic Cholecystectomy

Study Overview
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Brief Summary
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The laparoscopic approach has become the gold standard for many abdominal surgical procedures, including cholecystectomy. Compared to laparotomy, laparoscopy allows smaller incisions, reduces perioperative stress response, reduces postoperative pain, and results in shorter recovery time. However, anaesthesia concerns in patients undergoing laparoscopic surgery are different from patients undergoing open abdominal surgery. The aim of this study is to investigate the effect of the external oblique intercostal block, which is a new block, on postoperative pain score and opioid consumption.

Official Title
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Ultrasound Guided External Oblique Intercostal Plane Block vs. Transversus Abdominis Plane Block for Laparoscopic Cholecystectomy: Prospective Randomized Study

Conditions
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Analgesia

Intervention / Treatment
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* Other: ultrasound guided external oblique intercostal plane block
* Other: Subcostal Transversus Abdominis Plan Block Group


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: American Society of Anesthesiologist's physiologic state I-III patients Laparoscopic cholecystectomy Exclusion Criteria: Chronic pain bleeding disorders renal or hepatic insufficiency patients on chronic non-steroidal anti-inflammatory medications emergency cases

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: External oblique intercostal plane block<br>Ultrasound-guided External oblique intercostal plane block before surgery | Other: ultrasound guided external oblique intercostal plane block<br>* ultrasound guided external oblique intercostal plane block 20 ml local anesthetic each side<br>|
| Active Comparator: Subcostal Transversus Abdominis Plan Block Group<br>Ultrasound-guided Subcostal Transversus Abdominis Plan Block Group | Other: Subcostal Transversus Abdominis Plan Block Group<br>* ultrasound guided Subcostal Transversus Abdominis Plan Block Group 20 ml local anesthetic each side<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative opioid consumption | First 24 hours total fentanyl consumption with patient controlled analgesia | first 24 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual analog pain score | Post operative pain will be evaluated with a Visual Analogue Scale (VAS) score of 0-10 (0= no pain and 10= worst imaginable pain) | postextubation 0-24 hours |