Patient Controlled Oral Analgesia for Postoperative Pain Management After Total Knee Replacement

Study Overview
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Brief Summary
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Patient Centered Care (PCC) is an approach that consciously adopts the patient's perspective...about what matters (Gerteis, Edgeman, Levitan, Walker, Stokes, Cleary, Delbanco, 1993). Experiencing pain is the most common concern of patients before surgery - even ahead of whether the surgery would improve their condition (Apfelbaum, 2003). Current standard of practice for post-operative pain management in most acute care hospitals today is intravenous patient controlled analgesia (IV PCA). However, despite the fact that patients prefer IV PCA because it affords them greater control and provides them with better pain relief (Ballantyne, Carr, deFerranti, Suarez, Lau, Chalmers, Angelillo, Mosteller, 1998 ; Rawal, 2001), hospitals routinely take control of pain medications away from patients once they are switched to pain tablets. Patients must then wait, in pain, for their nurse to bring them pain tablets. Patient controlled oral analgesia (PCOA) has been utilitzed in several centers in the US and Germany. Preliminary evidence from the literature seems to indicate that the benefits of PCOA are similar to IV PCA including increased patient satisfaction and better pain control (Striebel, Romer, Kopf, Schwagmeier ,1996; Striebel, Scheitza, Philippi, Behrens, Toussaint, 1998). At the Toronto Western Hospital, University Health Network, we have successfully implemented a PCOA program on two surgical units (Orthopedics/Rheumatology and Spinal). The purpose of this study is to compare usual nurse administered oral analgesia to PCOA with respect to pain, patient satisfaction, and passive range of knee motion in postoperative total knee replacement patients.

Official Title
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Patient Controlled Oral Analgesia (PCOA) for Postoperative Pain Management After Total Knee Replacement-A Pilot Study

Conditions
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Self-Administered Versus Nurse Administered Pain Medication.

Intervention / Treatment
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* Behavioral: Self-administration or nurse administered medication


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: able to read and write English post elective total knee replacement surgery (primary or revision) already on IV PCA age 18-80 able to tolerate oral medication able to physically open a childproof vial independently (including the absence of any significant problems with manual power, dexterity or visual acuity) able and willing to complete Oral PCA flowsheet Exclusion Criteria: history of substance abuse history of sleep apnea episode(s) of confusion, disorientation during this admission episode(s) of respiratory depression during this admission history of major psychiatric disorder pregnancy

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: Self-administration or nurse administered medication|nan|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |