Cognitive Skills Training for Homeless Youth

Study Overview
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Brief Summary
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Many young people who are homeless have cognitive deficits which impede their ability to secure and maintain employment. This study looks to see if targeting cognitive deficits can improve cognition and vocational outcome.

Detailed Description
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The aim of this research is to conduct a controlled study of cognitive remediation, to provide feasibility data on adapting an established empirically-based cognitive intervention for homeless youth to help them attain vocational goals. The ultimate purpose is that youth will improve in cognitive functioning and have better functional outcomes including jobs to sustain independent living. The results of this study will inform a larger trial on the efficacy of cognitive remediation in homeless youth to improve cognition and vocational outcomes. Hypotheses are that, compared to those in an active control group receiving computerized work-skills training, individuals who receive cognitive remediation will show greater cognitive benefits on proximal measures of neurocognition and evidence better vocational outcome as defined by greater number of hours worked. This study will address the service gap in the use of integrated psychosocial interventions for homeless populations as the first investigation of cognitive remediation in homeless youth.

Official Title
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Cognitive Skills Training to Improve Vocational Outcome in Homeless Youth

Conditions
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Substance Abuse, Affective Disorders, Anxiety Disorders, Attention Deficit Disorder

Intervention / Treatment
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* Behavioral: Cognitive Remediation
* Behavioral: Computer Skills Training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: have a current Diagnostic and Statistical Manual (DSM-IV) Axis I diagnosis residing at Covenant House New York Rights of Passage Program psychiatrically stable for at least 21 days English speaking Exclusion Criteria: mental retardation (<70 Intelligence Quotient; IQ) on premorbid intelligence estimate) risk for suicide or violence unremitted substance dependence within the past 6 weeks

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 22 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Computer skills training<br>26 sessions conducted 2-3 times a week to train in computer skills related to the workforce. | Behavioral: Computer Skills Training<br>* Participants utilize an interactive software program that delivers tutorials, lessons, and practice sessions to develop computer skills for office based employment. During the learning activities, the clinician offers coaching and assistance in setting up computerized training exercises as needed.<br>|
| Experimental: Cognitive Remediation<br>26 sessions conducted 2-3 times a week of cognitive remediation | Behavioral: Cognitive Remediation<br>* Neuropsychological Educational Approach to Remediation (NEAR) is an evidence based, manualized cognitive remediation program that targets cognitive deficits (eg memory, processing speed, executive functioning, working memory and attention) with the intent of improving daily functioning.NEAR is conducted in a small group setting, allowing for supportive social interaction while participants work at their own computer station on engaging computerized activities that are selected to address their unique profile of cognitive deficits. Then, as a group they discuss how their respective cognitive activities will help them achieve their vocational goals.<br>* Other names: NEAR;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Global Cognition Score | A Global Cognition Score will be derived from the average z scores in five domains of cognitive functioning: working memory, verbal memory, processing speed, executive functioning, and attention. | Baseline, 13, 26 sessions | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Vocational outcome | The vocational outcome will be total number of hours worked. Hours worked per week (range of 0 to 40) will be summed from the time of session 1 of cognitive remediation/active control to the time of one month followup. | Baseline, 13, 26 sessions |