Gingivitis Treated With Chlorhexidine 0.12% Mouthwash in Young Adults

Study Overview
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Brief Summary
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The aim of this study will evaluate the effectiveness of 0.12% chlorhexidine solution as an anti-inflammatory agent and reducing the presence of biofilm in young adults.

Detailed Description
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Thirty patients with gingivitis ages 18 to 30 year with a probing depth of at most 3 mm and at least 20 teeth will be selected and evaluate at baseline and after 4 weeks.

Official Title
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Gingivitis Treated With Chlorhexidine 0.12% Mouthwash in Young Adults

Conditions
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Age Problem

Intervention / Treatment
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* Procedure: 0.12% chlorhexidine


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Presence of gingivitis Probing depth (PD) with maximum 3 mm Minimum of 20 teeth Age between 18 and 30 years old Exclusion Criteria: Patients with periodontal disease (PD ≥ 4mm with clinical attachment loss) Diabetes Osteoporosis Pregnant or lactating females Smokers Users of immune suppressive medication Phenytoin or cyclosporine Calcium channel blockers Antibiotics Nonsteroidal anti-inflammatory drugs HIV+ or AIDS

Ages Eligible for Study
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Minimum Age: 30 Days
Maximum Age: 30 Days

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Thirty patients with gingivitis ages18 to 30 year with a probing depth of at most 3 mm and at least 20 teeth will select and evaluate at baseline and after 4 weeks. The periodontal clinical parameters will verify: plaque index (PI), gingival index (GI) and Simplified Oral Hygiene Index (OHIS). After evaluation of the clinical parameters, the patients will randomly allocated into two groups of 15 individuals to rinse with antimicrobials twice a day for a period of four weeks. Group A, received 0.12% chlorhexidine antimicrobian in a vial previously identified as solution 1 and group B, received saline solution identified as solution 2.
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Solution 1<br>0.12% chlorhexidine | Procedure: 0.12% chlorhexidine<br>* the patients were randomly allocated into two groups of 15 individuals to rinse with antimicrobials twice a day for a period of four weeks. Group A, received 0.12% chlorhexidine antimicrobian in a vial previously identified as solution 1 and group B, received saline solution identified as solution 2.<br>* Other names: Saline Solution;|
| Placebo Comparator: Solution 2<br>Saline solution | Procedure: 0.12% chlorhexidine<br>* the patients were randomly allocated into two groups of 15 individuals to rinse with antimicrobials twice a day for a period of four weeks. Group A, received 0.12% chlorhexidine antimicrobian in a vial previously identified as solution 1 and group B, received saline solution identified as solution 2.<br>* Other names: Saline Solution;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Plaque Index | Check the biofilm as Ainano & Bay 1975 index, Higher levels means worse. | 30 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Gingival Index | Check the biofilm as Ainano & Bay 1975 index, Higher levels means worse. | 30 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Gingivitis, Periodontal treatment