Improving Mother Milk Feeding Benefits in Neonatal Intensive Care Units

Study Overview
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Brief Summary
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Twenty-seven hospitals in China will participate in the study, which aims to increase breastfeeding rate in the neonatal intensive care unit (NICU) and reduce the clinical complications in very low birth weight infants and extremely low birth weight infants.

Detailed Description
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Breast milk reduces the risk of serious prematurity related morbidities. Quality improvement is an effective means of increasing breast milk feeding.Twenty-seven hospitals in China will participate in the study, which aims to increase breastfeeding rate in the NICU and reduce the clinical complications in very low birth weight infants and extremely low birth weight infants. This study compared the clinical data of very low birth weight infants and extremely low birth weight infants in three phases：Before-intervention phase，Intervention phase and Sustainability phase. During the Intervention phase and Sustainability phase multiple intervention bundles of quality improvement were implemented.The investigators will compare breast milk feeding rate and neonatal outcomes in different phases.

Official Title
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Improving Mother Milk Feeding Benefits in Neonatal Intensive Care Units Using the Evidence-based Practice for Quality Improvement

Conditions
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Quality Improvement, Breast Milk

Intervention / Treatment
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* Behavioral: Quality improvement of breast milk feeding


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: premature Infants (Birth weight<1500g) Exclusion Criteria: mother with sever illness or communicable disease

Ages Eligible for Study
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Maximum Age: 120 Days

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: Before-intervention phase<br>All the very low birth weight (VLBW) and extremely low birth weight (ELBW) infants who were admitted from January 2017 to December 2017 to the NICUs of different hospitals. | |
| Experimental: Intervention phase<br>All the VLBW and ELBW infants who were admitted from January 2018 to December 2018 to the NICUs.During this phase,multiple intervention bundles of quality improvement will be implemented. | Behavioral: Quality improvement of breast milk feeding<br>* During the Intervention phase and Sustainability phase ,The NICUs will receive training of multiple evidence based quality improvement methods.<br>|
| Experimental: Sustainability intervention phase<br>All the VLBW and ELBW infants who were admitted from January 2019 to December 2019to the NICUs.In the Sustainability intervention phase,multiple intervention bundles of quality improvement will be continuous implemented. | Behavioral: Quality improvement of breast milk feeding<br>* During the Intervention phase and Sustainability phase ,The NICUs will receive training of multiple evidence based quality improvement methods.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| mother own milk feeding rates |  | three years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| NICU costs | costs during hospitalization in NICU | three years | 
| the incidence of necrotizing enterocolitis (NEC) | the incidence of necrotizing enterocolitis | three years | 
| the incidence of sepsis |  | three years | 
| Reduce the incidence of enteral feed intolerance |  | three years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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quality improvement, breast milk