linjc16/ctgov huggingface dataset:
Long-term Effect of Online Mental Health Literacy Training

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to assess the effectiveness over time of an online mental health in sport module in improving mental health literacy, stigma, and help-seeking behaviors in a sample of Brock student-athletes. Student-athletes will be assigned to one of two conditions, mental health module or the waitlist condition. The mental health module will consist of completing the Supporting Student-Athletes Mental Wellness online module for the student-athlete by the National Collegiate Athletics Association (NCAA). Participants will complete surveys at pre-intervention, post-intervention, 3-months and 6-month time points.

Official Title
-----------------
Investigating the Long-term Effect of Online Mental Health Literacy Training in Intercollegiate Sport

Conditions
-----------------
Mental Health Literacy, Waitlist

Intervention / Treatment
-----------------
* Other: Supporting Student-Athletes Mental Wellness


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: student-athletes Exclusion Criteria: non student-athletes
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Health Services Research
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Intervention<br>Receives the supporting student-athlete mental wellness module | Other: Supporting Student-Athletes Mental Wellness<br>* The module addresses: 1) managing your own mental wellness; 2) signs and symptoms of mental health problems; 3) role of student-athletes in creating a positive team environment that is supportive of mental health care seeking; 4) the role of a student-athlete in helping teammates; 5) how to identify emergency and non-emergency mental health situations.<br>|
| No Intervention: Waitlist<br>Receives no intervention | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Multicomponent Mental Health Literacy Measure | Multicomponent Mental Health Literacy Measure | 72 hours pre-intervention, 72 hours post-intervention, 3-months post, 6-months post | 
| Change in Self-Stigma | Self Stigma of Seeking Help Survey | 72 hours pre-intervention, 72 hours post-intervention, 3-months post, 6-months post | 
| Change in Help seeking intentions | General Help-Seeking Questionnaire | 72 hours pre-intervention, 72 hours post-intervention, 3-months post, 6-months post |
Detection of Brain Metastasis by MRI in Metastatic Colorectal Cancer Patients

Study Overview
=================
Brief Summary
-----------------
The aim of this study is to prospectively determine the incidence of brain metastases in metastatic colorectal cancer patients using systematic annual screening by MRI.

Official Title
-----------------
Dépistage Des métastases cérébrales Par IRM Chez Les Patients Avec un adénocarcinome Colorectal métastatique

Conditions
-----------------
Metastatic Colon Cancer

Intervention / Treatment
-----------------
* Device: Magnetic resonance imaging


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with histologically proven colorectal adenocarcinoma Metastases from colorectal cancer diagnosed since less than 6 months Indication of an oncologic treatment Exclusion Criteria: Patient with contraindication for MRI Diagnosis of cancer other than colorectal cancer in the last three years, except in situ cancers, basal-cell skin cancer or squamous-cell skin cancer, and other cancer with low risk of brain dissemination according to the investigator Pregnant or breastfeeding women, women of childbearing potential without effective contraception

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Screening
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Magnetic resonance imaging<br>Annual MRI during 3 years | Device: Magnetic resonance imaging<br>* Annually magnetic resonance imaging<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prospectively determine the incidence of brain metastases in metastatic colorectal cancer patients with annual MRI. | Diagnostic of brain metastases on annual MRI | 3 years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Brain metastasis, Magnetic resonance imaging
Delayed Positioning in Cesarean Section

Study Overview
=================
Brief Summary
-----------------
Maternal hypotension is a common problem during cesarian section under spinal anesthesia. The possible explanation for this is combined aortocaval compression by gravid uterus in parturient in addition to reduced systemic vascular resistance by spinal anesthesia. The investigators evaluated if the incidence of hypotension would be decreased by delayed supine positioning, by maintaining lateral position for 6 min after spinal injection, in patients undergoing elective cesarean section.

Conditions
-----------------
Hypotension

Intervention / Treatment
-----------------
* Other: lateral positioning


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: singleton parturients undergoing elective cesarean section gestational age over 37 weeks Exclusion Criteria: pregnancy with hypotension expecting fetal depression

Ages Eligible for Study
-----------------
Minimum Age: 28 Years
Maximum Age: 44 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: standard<br>parturients were placed back to the supine position immediately after spinal injection following standard protocol of spinal anesthesia | |
| Experimental: lateral<br>the lateral position was maintained for 6 min after spinal injection before patients were turned to the supine position | Other: lateral positioning<br>* the lateral position was maintained for 6 min after spinal injection before patients were turned to the supine position<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| hypotension | hypotension incidence after intrathecal injection until baby delivery. Monitoring about for 20 minutes | after intrathecal injection until delivery (for 20 minutes) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| sensory block level | highest sensory block level after intrathecal injection | during cesarean section |
The Effects of Age and Gender on the Advantage of Sniffing Position for Laryngoscopic View

Study Overview
=================
Brief Summary
-----------------
The sniffing position has been regarded as a standard position for direct laryngoscopic view. This study evaluated the effects of the age and gender on the advantage of the sniffing position compared with simple head extension for laryngeal view during direct laryngoscopy.

Conditions
-----------------
Laryngeal View

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: • Patients who are scheduled for elective surgery under general anesthesia Exclusion Criteria: • Patients with anatomical defects of the face, neck, or upper airway

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 90 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the percentage of glottic opening |  | during laryngoscopy |
Studies of Neuroendocrine and Energy Metabolism in Patients With Eating Disorders

Study Overview
=================
Brief Summary
-----------------
This study aims to investigate neuroendocrine, autonomic functioning, and energy metabolism in patients with eating disorder and their relationships with psychopathology of eating disorders (eating patterns, depression, and personality) in these patients.

Detailed Description
-----------------
The study subjects include female patients with DSM-IV diagnosis of AN (n = 30), BN (n = 60) and age-controled normal subjects (n = 30). They will receive a clinical interview and are asked to complete several self-administered questionnaires which included eating-related questionnaires, general psychological functioning scales and personality scales. After overnight fast, each subject undergoes a blood sample collection for neuroendocrine examination, body composition examination using BIA method, basal metabolic rate measurement by indirect calorimetry, and ECG in the morning between 0800 and 0900. Clinical patients would be asked to repeat filling the self-rating scales, weight and body fat measurement, as well as blood drawing again 2 months after treatment.

Official Title
-----------------
Studies of Neuroendocrine and Energy Metabolism in Patients With Eating Disorders

Conditions
-----------------
Anorexia Nervosa, Bulimia Nervosa

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Subjects who fulfilled DSM-IV diagnosis of anorexia nervosa or bulimia nervosa Normal controls Exclusion Criteria: Any major psychiatric disorders Use of psychoactive medications Drug and alcohol abuse Medical problems (cardiovascular condition and endocrine disorders)
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| 1<br> | |
| 2<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
eating disorders, ghrelin, leptin, BIA
Safety and Efficacy Evaluation of TPN in Preterm Neonates in NICU of Cairo University Children Hospital

Study Overview
=================
Brief Summary
-----------------
The aim of this work is evaluation of electrolytes and minerals homeostasis and occurrence of complications among preterm babies receiving total parenteral nutrition, and admitted to the neonatal intensive care units of Cairo University Children hospitals.

Official Title
-----------------
Safety and Efficacy Evaluation of TPN in Preterm Neonates in NICU of Cairo University Children Hospital

Conditions
-----------------
TPN in Preterm

Intervention / Treatment
-----------------
* Dietary Supplement: TPN


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: - All preterm infants with gestational age < 34 weeks, Receiving total parenteral nutrition. Normal serum magnesium. Exclusion Criteria: Any full-term neonates Any patient with TORCH infection, chromosomal, metabolic disorders or surgical abnormality of the hepatobiliary system

Ages Eligible for Study
-----------------
Minimum Age: 1 Day
Maximum Age: 1 Month

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Dietary Supplement: TPN|Total parenteral nutrition|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| electrolyte and mineral disturbance associated with TPN in preterm receiving it | NA, K, MG, P, CA. | 14 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| prevalence of cholestasis and sepsis in preterm receiving TPN | clinical and laboratory examination | 14 days |
Metabolic Equivalent of Task (MET) in the Preoperative Assessment in Aortic Surgery

Study Overview
=================
Brief Summary
-----------------
Reliable prediction of the preoperative risk is of crucial importance for patients undergoing vascular operations. The assessment of the metabolic equivalent of task (MET) is an easy clinical evaluation of the functional capacity of an individual. A MET is defined as the resting metabolic rate, that is the amount of the consumed oxygen at rest. According to the MET concept a patient would be considered as fit for surgery when the stairs of two flights can be climbed and the housework can be fully managed by oneself. Hypothesis: Patients with a functional capacity over 4 MET (fit for surgery) have less perioperative complications with the focus on cardiac pathology than patients with less than 4 MET during aortic operations. Patients and Method: Retrospective analysis of a single center unit of 296 patients undergoing open or endovascular aortic repair.

Official Title
-----------------
Metabolic Equivalent of Task (MET) in the Preoperative Assessment in Aortic Surgery

Conditions
-----------------
Aortic Diseases

Intervention / Treatment
-----------------
* Diagnostic Test: MET


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Data of all patients after open and endovascular aortic repair of the descending aorta from May 2009 till March 2016 Exclusion Criteria: Data of all patients with isolated operations on the ascending aorta or aortic arch

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 90 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| > 4 MET<br>Patients with functional capacity over 4 MET | Diagnostic Test: MET<br>* Testing of the metabolic equivalent of task before aortic procedure<br>|
| < 4 MET<br>Patients with functional capacity under 4 MET | Diagnostic Test: MET<br>* Testing of the metabolic equivalent of task before aortic procedure<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Survival | Mean survival during the whole follow up period of both groups, patients with less and more than 4 MET | up to ten years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Perioperative complications | Complications include perioperative myocardial infarction and stroke, re-operation during first admission (divided in greater and smaller re-operations) | up to 30 days postoperatively | 
| Coronary artery bypass grafting, percutaneous coronary intervention/Stenting | Interventions including revascularisation or other kind of heart surgery or treatment because of cardiac pathology | up to ten years |
Evaluate Different Extended-release (ER) Tablets/Capsules of AZD1305

Study Overview
=================
Brief Summary
-----------------
To study the properties of different tablets/capsules of AZD1305 in healthy male volunteers.

Official Title
-----------------
A Phase I, Two-part, Randomised, Open, Single-centre, Crossover Study to Evaluate Different Extended-release Formulations of AZD1305 When Given as Single Oral Doses to Healthy Male Volunteers

Conditions
-----------------
Healthy

Intervention / Treatment
-----------------
* Drug: AZD1305
* Drug: AZD1305


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Healthy male between the age of 20 - 45 Non-smoking Exclusion Criteria: Potassium outside normal reference values ECG findings outside normal range

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 45 Years

Sexes Eligible for Study
-----------------
Male

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Part A: 2x2 crossover<br>4 different AZD1305 ER formulations | Drug: AZD1305<br>* Extended release capsules, oral single doses<br>|
| Experimental: Part B: 3x3 crossover<br>2 different AZD1305 ER formulations and a reference formulation | Drug: AZD1305<br>* Extended release capsules, oral single doses<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pharmacokinetic variables |  | During all dosing visits | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Adverse events, ECG, safety laboratory, vital signs, physical examination |  | During the study | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
AZD1305, pharmacokinetics, Properties of different ER formulations
Dosing of Amicar and Measure of Fibrinolysis by TEG During Cardiac Surgery

Study Overview
=================
Brief Summary
-----------------
This study hopes to determine the optimal antifibrinolytic dosing to decrease bleeding and blood transfusion after cardiac surgery without increasing adverse events

Official Title
-----------------
The Effect of Standard vs Aggressive Dosing Regimens for Epsilon-aminocaproic Acid on a Quantifiable Parameter of Fibrinolysis as Measured by Thromboelastography

Conditions
-----------------
Aortic Disease

Intervention / Treatment
-----------------
* Drug: epsilon-aminocaproic acid (EACA)


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Ability to sign informed consent Elective cardiac surgery patients undergoing primary surgery involving circulatory arrest Exclusion Criteria: Inability to sign informed consent Baseline hypercoagulable condition as defined in medical record Coronary disease with untreated lesions or recent coronary stent placement Severe renal dysfunction (ESRD) as documented in medical record

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 99 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: epsilon-aminocaproic acid (EACA)<br>75mg/kg loading dose with infusion 15mg/kg/hr | Drug: epsilon-aminocaproic acid (EACA)<br> <br> * Other names: Amicar;|
| Experimental: EACA<br>125mg/kg loading dose of EACA followed by an infusion of EACA at 25mg/kg/hr for length of cardiac surgery. | Drug: epsilon-aminocaproic acid (EACA)<br> <br> * Other names: Amicar;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| degree of fibrinolysis as measured by thromboelastography | The primary objective of the study will be to determine if a change in EACA dosing for cardiac surgery cases involving circulatory arrest actually leads to a quantifiable change in the degree of fibrinolysis as measured by TEG. | Length of cardiac surgery | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
dilated ascending aorta
Intraarticular Xylitol Injections for Knee Osteoarthritis

Study Overview
=================
Brief Summary
-----------------
Hypothesis: Intraarticular injections of isotonic Xylitol solution will improve pain in patients with knee osteoarthritis (OA).

Official Title
-----------------
Intraarticular Xylitol Injections for Knee Osteoarthritis

Conditions
-----------------
Knee Osteoarthritis

Intervention / Treatment
-----------------
* Device: Xylitol


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age over 45 Tibiofemoral osteoarthritis OA stage 2-3 on xray Pain VAS > 40mm No NSAIDs for 3 weeks No analgetics for 38 hours Exclusion Criteria: Pain VAS > 80mm Pain VAS in contralateral knee > 40mm Inflammatory arthritis Severe effusion Posttraumatic osteoarthritis Unstable knee Isolated patellofemoral disease Paracetamol hypersensitivity

Ages Eligible for Study
-----------------
Minimum Age: 45 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Xylitol injection<br>Intraarticular injection of Xylitol | Device: Xylitol<br> <br> |
| Placebo Comparator: Control<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain - visual analogue scale |  | 3 months |
Physiological Biomarkers of Cancer Treatment Related Fatigue in Women With Breast Cancer.

Study Overview
=================
Brief Summary
-----------------
Physiological Biomarkers of Cancer Treatment Related Fatigue in Women with Breast Cancer.

Detailed Description
-----------------
As above.

Official Title
-----------------
Physiological Biomarkers of Cancer Treatment Related Fatigue in Women With Breast Cancer.

Conditions
-----------------
Breast, Cancer

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Newly diagnosed early stage breast cancer. Exclusion Criteria: Not specified.
Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Disease Progression |  | 3 years |