linjc16/ctgov huggingface dataset:
Sugars-sweetened Beverages and Exercise on Glycaemic Response and Subjective Appetite in Children

Study Overview
=================
Brief Summary
-----------------
The purpose of the study is to understand the role chocolate milk compared to a fruit drink, with and without exercise, on glycaemic regulation and subjective appetite in children. The investigators hypothesize that chocolate milk in combination with exercise will have the greatest effect attenuating glycaemic response. Blood glucose will be measured by finger prick following drink consumption (0 min) and exercise or sitting (15 min), and at 65 minutes. Subjective appetite will be measured at 0, 20, 35, 50 and 65 minutes.

Official Title
-----------------
The Role of Chocolate Milk and Fruit Drink on Subjective Appetite and Glycaemic Response With or Without Exercise in Normal Weight 9-14 Year Old Boys

Conditions
-----------------
Glycemic Control, Subjective Appetite

Intervention / Treatment
-----------------
* Dietary Supplement: Chocolate Milk
* Dietary Supplement: Fruit Drink
* Behavioral: Exercise


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Healthy, boy, born at full term and normal birth weight Exclusion Criteria: Girls, have significant learning, behavioral, or emotional difficulties

Ages Eligible for Study
-----------------
Minimum Age: 9 Years
Maximum Age: 14 Years

Sexes Eligible for Study
-----------------
Male

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Chocolate Milk Beverage<br>Chocolate milk beverage and sitting quietly | Dietary Supplement: Chocolate Milk<br> <br> |
| Experimental: Chocolate Milk Beverage and Exercise<br>Chocolate milk beverage and exercising | Dietary Supplement: Chocolate Milk<br> <br> Behavioral: Exercise<br> <br> |
| Experimental: Fruit Drink Beverage<br>Fruit drink beverage and sitting quietly | Dietary Supplement: Fruit Drink<br> <br> |
| Experimental: Fruit Drink Beverage and Exercise<br>Fruit drink beverage and exercising | Dietary Supplement: Fruit Drink<br> <br> Behavioral: Exercise<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Blood Glucose (mmol/L) | Blood Glucose (mmol/L) determined by fingerprick glucometer reading | at baseline (0), 20 and 65 minutes | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Subjective Appetite (mm) | Subjective appetite (in mm) determined by visual analogue scale will be determined at 0, 20, 35, 50 and 65 minutes. | 0 - 65 mins |
Usability of a Breathing-CBT Platform (CBT = Cognitive Behavioural Therapy)

Study Overview
=================
Brief Summary
-----------------
The study will examine the usability of a breathing platform in the home environment. It will be a randomized, open-label crossover study of 10 participants who will complete the CBT and breathing components in their home, prior to sleeping. Usability will be measured by scores assigned by participants. Qualitative feedback and compliance information will also be collected.

Official Title
-----------------
Breathing and CBT Platform Usability Take-home Study

Conditions
-----------------
Breathing, Mouth

Intervention / Treatment
-----------------
* Device: Therapy
* Other: No device


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Participants are willing to give written, informed consent Participants are healthy adults Participants are able to comprehend and speak English Participants are at least 18 years of age Exclusion Criteria: Participants who are/may be pregnant or lactating Participant that have a pre-existing lung disease/ condition that would predispose them to pneumothorax (for example: COPD, lung cancer; fibrosis of the lungs; recent (< 2years) case of pneumonia or lung infection; lung injury) Participants who are unsuitable for the inclusion at the discretion of the investigator

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Control with no device<br>Breathing performed with no device | Other: No device<br>* Breathing platform without device<br>|
| Experimental: Therapy - device assisted breathing<br>Breathing performed with device | Device: Therapy<br>* Device-assisted breathing for relaxation<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Ease of use | Participants will complete a questionnaire rating how easy it was to use and sleep with the device providing assistance to their breathing patterns | 8 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Compliance | Frequency of use, as assessed by a short questionnaire asking how often patients used the device | 8 days |
Test-retest Stability of MR-parameters. A Neuroimaging Pilot-study in Healthy Volunteers

Study Overview
=================
Brief Summary
-----------------
Aim: To study the stability of brain MR-scanning parameters (blood-flow, microstructure, volume, metabolism) over 1 week in health volunteers. Hypothesis: MR-scanning parameters are stable over 1 week in healthy volunteers

Official Title
-----------------
Test-retest Stability of MR-parameters. A Neuroimaging Pilot-study in Healthy Volunteer

Conditions
-----------------
Magnetic Resonance

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: age 18-65 oral and written consent Exclusion Criteria: intracranial disease previous intracranial surgery magnetic implant or magnetic foreign body claustrophobia

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| healthy volunteers<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| cortical volume/thickness |  |  |
N-Acetyl Cysteine After Cervical Cerclage

Study Overview
=================
Brief Summary
-----------------
The aim of the study is to evaluate the effect of N-acetyl cysteine (NAC) on pregnancy outcome in women undergoing cervical cerclage for cervical insufficiency.

Detailed Description
-----------------
A randomized controlled clinical trial to be carried out in a university-affiliated tertiary center.Participating women will be randomized into two groups: Group A will be given an oral daily dose of 0.6 g of NAC in effervescent form; group B, serving as controls, will not receive NAC.The two groups will then be compared according to pregnancy outcome.

Official Title
-----------------
Effect of Oral N-Acetyl Cysteine on Pregnancy Outcome After Cervical Cerclage: a Randomized Controlled Trial

Conditions
-----------------
Cervical Cerclage

Intervention / Treatment
-----------------
* Drug: N-Acetyl Cysteine
* Drug: Placebo


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: women with history suggestive of cervical insufficiency together with ultrasound findings suggestive of cervical insufficiency undergoing elective cervical cerclage between the 11th and 12th gestational week. singelton viable fetus Exclusion Criteria: women tested positive for bacterial vaginosis women currently with threatened abortion (vaginal bleeding or uterinecramps) age older than 35 years or younger than 20 years unwillingness to participate irregular and/or uncertain menstrual dates rupture of membranes previous cesarean delivery possible risks for preterm birth in the current or previous pregnancy such as twin pregnancy, IUFD, malpresentation, known fetal anomaly, progesterone or heparin treatment during the current pregnancy, hypertension, and/or seizure disorders. women with contra indications for cervical cerclage or anesthesia.

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 35 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: 1<br>N-Acetyl Cysteine | Drug: N-Acetyl Cysteine<br>* oral daily dose of 0.6 g of N-acetyl cysteine in effervescent form<br>* Other names: placebo;|
| Placebo Comparator: 2<br>placebo | Drug: Placebo<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Gestational age at delivery |  | 3-6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Take home babies, neonatal morbidity |  | 3-6 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
N-acetyl cysteine (NAC), Cervical cerclage, cervical cerclage for cervical insufficiency
Detection of LADA in a Hospital in the Mexican Southeast

Study Overview
=================
Brief Summary
-----------------
Patients with Latent Autoimmune Diabetes in Adults (LADA) show autoantibodies that indicate an autoimmune pathogenesis. Glutamic acid decarboxylase autoantibodies (GADA) are most prevalent islet autoantibodies in European patients with LADA. In this sense, it is considered that it is sufficient to determine GADA to identify subjects with LADA from patients with T2D for research purposes. Therefore, the aim was to investigated the presence of GADA in serum of subjects with T2D and its relationship with clinical criteria, metabolic control, drug treatment, and diabetes complications to identify possible patients with LADA in a hospital in southeastern Mexico is worthwhile. The sample was recruited at the Diabetes Clinic of the Regional Hospital of High Specialty Dr. Gustavo A. Rovirosa Pérez, in the period from January 2020 to May 2021. The diagnosis was based in accordance with World Health Organization (WHO, 1999) criteria. Inclusion criteria: 1) patients previously diagnosed with T2D, 2) absence of insulin requirement for at least 6 months after diagnosis, 3) > 30 and < 50 years old at diabetes diagnosis, 4) BMI < 40 kg/m2, 5) subjects who agreed to participate in the study and signed the informed consent before the interview. Serum GADA and other biochemical concentrations were determined by an enzymatic immunoassay method (Human Anti-Glutamic Acid Decarboxylase ELISA Kit; MyBioSource).

Official Title
-----------------
Detection of Latent Autoimmune Diabetes in Adults, Clinical and Metabolic Profile in Patients Treated at the Diabetes Clinic in a Hospital in the Mexican Southeast.

Conditions
-----------------
Latent Autoimmune Diabetes

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients previously diagnosed with T2D, absence of insulin requirement for at least 6 months after diagnosis, > 30 and < 50 years old at diabetes diagnosis, BMI < 40 kg/m2, subjects who agreed to participate in the study and signed the informed consent before the interview. Exclusion Criteria: • patients with other types of diabetes, and subjects who did not agree to participate.

Ages Eligible for Study
-----------------
Minimum Age: 30 Years
Maximum Age: 50 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| GADA in serum of subjects with T2D | Serum GADA concentrations were determined by an enzymatic immunoassay method in subjects with T2D | May 2021 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
LADA, GADA, Mexican population
The Rise in Robotic Atypical Segmentectomies

Study Overview
=================
Brief Summary
-----------------
This study investigates the increased rate of robotic atypical segmentectomies. Segmentectomy refers to removing a section of a lobe of the lung. Reviewing patients' data retrospectively may help researchers determine whether robotic surgery has led to an increase in atypical segmentectomy.

Detailed Description
-----------------
PRIMARY OBJECTIVES: I. To evaluate the rate of increase in robotic segmentectomies performed at our institution per year. II. To evaluate the rate of typical and atypical segmentectomies performed at our institution per year. III. To characterize the differences in robotic versus other types of resections such as open and VATS (video-assisted thoracic surgery). OUTLINE: Patients' medical records are reviewed retrospectively.

Official Title
-----------------
The Rise in Robotic Atypical Segmentectomies: A Large Cancer Center Experience

Conditions
-----------------
Lung Carcinoma

Intervention / Treatment
-----------------
* Other: Electronic Health Record Review


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients who underwent a lung resection from 2004 to 2019
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Observational (medical record review)<br>Patients' medical records are reviewed retrospectively. | Other: Electronic Health Record Review<br>* Review of medical records<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rate of change in robotic segmentectomies |  | Up to 2 years | 
| Rate of typical and atypical segmentectomies |  | Up to 2 years | 
| Differences in robotic versus other types of resections such as open and video-assisted thoracic surgery |  | Up to 2 years |
Comparison of Educational Services and Outcomes for Patients Treated for Childhood Cancer

Study Overview
=================
Brief Summary
-----------------
The purpose of the study is to evaluate some educational outcomes of children treated for childhood cancer.

Detailed Description
-----------------
The aim of this telephone survey was to test the efficacy of systemic educational program services in improving school outcomes as compared to hospitals who provide educational liaison services in an ad hoc manner.Data from this study will be used to help secure funding to surther investigate the broader use of educational liaison services.

Official Title
-----------------
Comparison of Educational Services and Outcomes for Patients Treated for Childhood Cancer and Brain Tumor in Facilities With and Without Educational Liaison Services.

Conditions
-----------------
Cancer, Brain Tumor

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: must have had childhood cancer or brain tumor and been diagnosed between 1994-2001 and at least 6 years of age at diagnosis. must have been treated at Golisano Children's Hospital or Children's Hospital of Pittsburgh Exclusion Criteria: less than 6 years of age

Ages Eligible for Study
-----------------
Minimum Age: 6 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
learning, cancer, education, brain tumor, school
Anti-pseudomonas IgY to Prevent Infections in Cystic Fibrosis

Study Overview
=================
Brief Summary
-----------------
Hypothesis: Daily gargling with specific avian antibodies against Pseudomonas aeruginosa will prevent infections with this bacteria in patients with Cystic fibrosis (CF).

Detailed Description
-----------------
Anti-pseudomonas IgY is prepared from eggs of hens that have been vaccinated with Pseudomonas aeruginosa. The hens farm is under veterinary control according to Swedish rules. The drug is prepared with a water dilution method according to GMP standards (approved by Swedish MPA). Patients with CF who are intermittently but not chronically infected with P. aeruginosa get a short course of antibiotics to eradicate the bacteria. Thereafter they start to gargle with a solution of anti-pseudomonas IgY every night to prevent a new infection. Preliminary results have shown that it takes a significantly longer time to get a new infection and that the patients get fewer infections than control patients. In addition, results tentatively indicate that: patients have not got any new opportunistic bacteria or fungi (B. Cepacia, S. Maltophilia, A. Xylosoxidans, atypical Mycobacteria, Aspergillus Fumigatus); that use of antibiotics is greatly diminished; that the lung functions and nutritional conditions are maintained.

Official Title
-----------------
Post Marketing Study of Anti-pseudomonas IgY in Prevention of Recurrence of Pseudomonas Aeruginosa Infections Infections in Cystic Fibrosis (CF) Patients

Conditions
-----------------
Cystic Fibrosis, Infection, Pseudomonas Aeruginosa

Intervention / Treatment
-----------------
* Drug: Anti-pseudomonas IgY gargle


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Clinical diagnosis of cystic fibrosis Colonized with Pseudomonas aeruginosa informed consent Exclusion Criteria: Egg allergy
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Anti-pseudomonas IgY gargle<br>Intervention: Gargles with anti-pseudomonas IgY every night | Drug: Anti-pseudomonas IgY gargle<br>* Gargle (solution), > 5FKU, every night after toothbrushing, life-long<br>* Other names: Yolk antiboidies;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Sputum culture positive for Pseudomonas aeruginosa |  | Prospective | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pulmonary function |  | Prospective | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Cystic fibrosis, Prevention, Infection, Pseudomonas aeruginosa, Gargle
Pain Management in Internal Medicine Department

Study Overview
=================
Brief Summary
-----------------
The assessment of pain management in Internal medicine department.

Detailed Description
-----------------
The experimental procedure - A Literature review of the management of pain in internal departmnet and after that defining and identifying gaps between the pain management practice recommendations in the literatureareas to that of the departmnet. Determining the educational processes for the medical team, in initiation treatment for pain and pain assessment. As well, obtain quality indicators to monitor pain management. Assessment of attitudes, knowledge and tools for pain management team before the educational process and afterwards. In patients with mild pain or above, a combination of quantitative and qualitative tools will assess the pain and its treatment along the hospitalization in the Internal medicine ward.

Official Title
-----------------
Pain Management in Internal Medicine Department

Conditions
-----------------
Pain

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: All patient with mild pain and above Exclusion Criteria: None

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| pain reduction | Reviewing the pain scale (VAS or other) of a patient with mild pain during the hospitalization | during hospitalization (days)-up to7 days |
HEart Surgery In Atrial Fibrillation and Supraventicular Tachycardia

Study Overview
=================
Brief Summary
-----------------
Atrial fibrillation is the most common cardiac arrhythmia, the incidence of which increases drastically with age. As more and more elderly patients undergo heart surgery, the proportion of patients in this population will increase. Atrial fibrillation has been shown to be a poor prognostic factor in several surgical situations. The aim of our study was to assess long-term mortality among patients with preoperative AF under various cardiac surgery settings, with a particular emphasis on the strategy of coronary revascularization.

Official Title
-----------------
HEart Surgery In Atrial Fibrillation and Supraventicular Tachycardia

Conditions
-----------------
Atrial Fibrillation

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Referred for heart surgery, preoperative atrial fibrillation Exclusion Criteria: age<18 years old

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Death from any cause | Through polish national health fund we are able to determine patient status (dead or alive) | 2008-2020 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
atrial fibrillation, heart surgery, cabg, valve surgery, preoperative, mortality, grafts