Psychosocial Outcomes and Transition Readiness in Uveitis

Study Overview
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Brief Summary
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It is widely acknowledged that the transition from paediatric to adult health services should be a multidimensional and multidisciplinary process that addresses the medical, psychosocial, and educational needs of adolescents and young adults (AYA). Despite this, there is currently a scarcity of research examining the relationships between psychosocial factors (e.g., anxiety, social support) and transition readiness in AYA with uveitis. This study therefore aims to examine the relationships between psychosocial factors and transition readiness in pre-transfer adolescents and post-transfer young adults aged 10-25 years diagnosed with JIA at a single centre. In total, 25 adolescents aged 10-16 years, together with a parent/guardian, will participate at Sheffield Children's Hospital and 10 young adults aged 16-25 years will participate at Sheffield Teaching Hospitals. Participants completed a battery of self-report questionnaire measuring psychosocial factors (anxiety/depression, social support, family functioning, health-related quality of life) and transition readiness (transition knowledge and skills, self-efficacy). Uveitis disease severity was also measured during clinic appointments. A subset of participants will also be asked to take part in a focus group. This study received full ethical approval, and all participants will give their written informed assent or consent before taking part.

Official Title
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Describing Relationships Between Psychosocial Outcomes and Readiness for Transition in Adolescent and Young Adult Patients With Uveitis - a Pilot Study

Conditions
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Uveitis

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Diagnosis of uveitis Uveitis managed by either Sheffield Children's NHS Foundation Trust or Sheffield Teaching Hospitals NHS Foundation Trust Fluent in English Exclusion Criteria: No diagnosis of uveitis Uveitis not managed by either Sheffield Children's NHS Foundation Trust or Sheffield Teaching Hospitals NHS Foundation Trust Not fluent in English

Ages Eligible for Study
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Minimum Age: 10 Years
Maximum Age: 25 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Pre-Transfer Adolescents aged 10-16 years<br> | |
| Post-Transfer Young Adults aged 16-25 years<br> | |
| Parents/Guardians of Pre-Transfer Patients<br> | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Generalised Anxiety | Generalised Anxiety Disorder-7 Questionnaire (Spitzer et al., 2006) | Day 1, when participants complete the study questionnaire | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Depression | Patient Health Questionnaire-9 (Spitzer et al., 1999) | Day 1, when participants complete the study questionnaire | 
| Health-related quality of life | Paediatric Quality of Life Generic Module (Varni et al., 2002) | Day 1, when participants complete the study questionnaire | 
| Social support | Bath Adolescent Pain Questionnaire Social Support Subscale (Eccleston et al., 2005) | Day 1, when participants complete the study questionnaire | 
| Family functioning | Bath Adolescent Pain Questionnaire Family Functioning Subscale (Eccleston et al., 2005) | Day 1, when participants complete the study questionnaire | 
| Prosocial and problem behaviours | Strengths and Difficulties Questionnaire (Goodman, 1997) | Day 1, when participants complete the study questionnaire | 
| Uveitis disease severity | Standardization of uveitis nomenclature (SUN) scores will be used to assess uveitis disease severity. | Day 1, during hospital clinic appointment |