G-CREDIT (Gangnam-Cohort for Risk Evaluation of Diabetes and Impaired Glucose Tolerance)

Study Overview
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Brief Summary
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The prevalence of type 2 diabetes has consistently increased and type 2 diabetes can cause many types of vascular complications. Diabetes develops due to glucose intolerance. Early detection and intervention in the stage of glucose intolerance makes it afford to prevent overt diabetes and its complications. This study was designed to make a cohort of korean patients with glucose intolerance to construct a long term database about clinical characteristics of these patients.

Conditions
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Type 2 Diabetes, Impaired Glucose Intolerance

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients older than 20 years old who has visited Gangnam severance hospital since January 2007. Patients with either diabetes or impaired glucose tolerance Patients with at least 6 months of follow-up period Exclusion Criteria: 1. Patients with gestational diabetes, any active stage of cancer and severe disability

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 100 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Diabetes and Impaired glucose Tolerance (G-CREDIT)<br>Patients with either type 2 diabetes or impaired glucose tolerance who are older than 20 years old and have attended Gangnam Severance hospital for regular follow up. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Life style assessment - Past medical history - Smoking, alcohol history - Sleep, exercise, daily activity check - Diet - Reproductive status (Women only) - Socioeconomic status | Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications | an expected average of 12 weeks | 
| Past medical history | Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications | an expected average of 12 weeks | 
| Smoking, alcohol history | Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications | an expected average of 12 weeks | 
| Sleep, exercise, daily activity check | Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications | an expected average of 12 weeks | 
| Diet | Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications | an expected average of 12 weeks | 
| Reproductive status (Women only) | Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications | an expected average of 12 weeks | 
| Socioeconomic status | Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications | an expected average of 12 weeks | 
| Anthropometric measurements : Height, weight, waist circumference, pulse rate, blood pressure | Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications | an expected average of 12 weeks | 
| SMA, TG, HDL, LDLM apoA, apoB | Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications | an expected average of 12 weeks | 
| PC2hrs, HbA1C, Insulin, C-peptide (AC, PC2hr), hs-CRP | Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications | an expected average of 12 weeks | 
| Urine protein, albumin, creatinine | Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications | an expected average of 12 weeks | 
| EKG, Neurometer, Chest PA, Abdominal sonography | Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications | an expected average of 12 weeks | 
| Fundus photography, fat computed tomography | Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications | an expected average of 12 weeks | 
| HOMA-IR, HOMA-β | Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications | an expected average of 12 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Diabetes, DM complication