linjc16/ctgov huggingface dataset:
Micro-expression Reading Skill Training in Medical Students

Study Overview
=================
Brief Summary
-----------------
This study was undertaken to investigate the effectiveness of the Micro Expression Training Tool (METT) and the Subtle Expression Training Tool (SETT) to help improve the non-verbal communication skills of medical students.

Detailed Description
-----------------
Teaching and assessing communication skills is an important component of medical school curricula, and it is not easy for medical students to develop non-verbal communication skills without adequate training. This study was undertaken to investigate the effectiveness of the Micro Expression Training Tool (METT) and the Subtle Expression Training Tool (SETT) to help improve the non-verbal communication skills of medical students.

Official Title
-----------------
Effects of Micro- and Subtle-expression Reading Skill Training in Medical Students

Conditions
-----------------
Communication

Intervention / Treatment
-----------------
* Other: Micro Expression Training Tool


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Year 1 and 2 medical students, PNUSOM Exclusion Criteria: incomplete survey response

Ages Eligible for Study
-----------------
Minimum Age: 25 Years
Maximum Age: 35 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: training group<br>41 training students were pre-tested before education with Micro Expression Training Tool (METT) and Subtle Expression Training Tool (SETT) at baseline and then, took second METT and SETT tests after a 1-hour class about interpreting micro and subtle expressions. | Other: Micro Expression Training Tool<br>* The Micro Expression Training Tool (METT) and the Subtle Expression Training Tool (SETT) to help improve the non-verbal communication skills<br>|
| No Intervention: control group<br>41 control students were pre-tested before education with METT and SETT at baseline and then, took the second tests without attend the training class. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Expression Training Tool score | difference of Micro and Subtle Expression Training Tool score between pre-test and post-test | through study completion, 1 year |
Connection, Navigation, Engagement in Care and Treatment for Opioid Use Disorder

Study Overview
=================
Brief Summary
-----------------
The overarching goal of the study is to develop, pilot, and evaluate an intervention that aims to retain patients who initiate buprenorphine at Denver Health in ongoing treatment for opioid use disorder.

Detailed Description
-----------------
Initiating patients identified with opioid use disorder in hospital settings onto buprenorphine is a relatively new strategy to prevent overdose. While the literature is beginning to amass showing the effectiveness of this strategy for initiating people into treatment, a dearth of data to describe how well people are maintained in treatment remains. The current research project aims to 1) develop an intervention to enhance engagement and retention in treatment for individuals with opioid use disorder who initiate buprenorphine at Denver Health and 2) assess acceptability, feasibility, and initial efficacy of an intervention to enhance engagement and retention in treatment for individuals with opioid disorder compared to usual care.

Official Title
-----------------
Linkage Navigation to Enhance Initiation and Engagement in Treatment for Opioid Use Disorder to Prevent Overdose

Conditions
-----------------
Opioid-use Disorder

Intervention / Treatment
-----------------
* Behavioral: Case management


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 18 years and older inducted onto buprenorphine at Denver Health successfully completed an intake visit at Denver Health's Outpatient Behavioral Health Services clinic. Exclusion Criteria: unable to provide informed consent unable to provide detailed contact information previously enrolled in the current study pregnant women will be excluded given that they are a priority treatment population and receive special services

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 99 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Intervention<br>dedicated case management | Behavioral: Case management<br>* dedicated case management to address social support needs<br>|
| No Intervention: Usual care<br>usual care | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Retention in treatment at 90 days | Defined by proportion of participants retained in care at 90 days, as measured by the total number of intakes where patient has continued to be engaged in medication assisted treatment at 90 days from start of treatment divided by the total number of intakes where patients linked to follow up dosing or prescription, for each arm. | 90 days from treatment initiation |
Florida Center for Brain Tumor Research

Study Overview
=================
Brief Summary
-----------------
The purpose of this research study is to collect and store brain tumor tissue samples for future research. The samples will become part of the University of Florida Brain Tumor Tissue Bank/Florida Center for Brain Tumor Research. The goal is to find improved treatments and cures for brain tumors.

Detailed Description
-----------------
The mission of the Florida Center for Brain Tumor Research is to discover cures for brain tumors and develop innovative brain tumor treatment modalities by providing a central repository for brain tumor biopsies and clinical information from individuals throughout the state of Florida, improving brain tumor biomedical research programs within the state of Florida, facilitating funding opportunities, fostering collaboration with brain tumor research organizations and other institutions, and fostering improved technology transfer of brain tumor research findings into clinical trials and widespread public use. The Florida Center for Brain Tumor Research will collect and store left-over tissue that is not needed for medical care or diagnosis in a tissue bank in the Evelyn F. and William L. McKnight Brain Institute at the University of Florida. Tissue, medical information, cerebrospinal fluid, blood and answers to Quality of Life questionnaires will be stored and made available to researchers. Although developed for Florida, tumor tissue from all other states would be accepted.

Official Title
-----------------
Establishment of a UF Brain Tumor Tissue Bank: Florida Center for Brain Tumor Research

Conditions
-----------------
Brain Tumors

Intervention / Treatment
-----------------
* Procedure: Tissue Bank


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Children and adults scheduled to undergo brain surgery to remove tumor tissue.
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Tissue Bank<br>Collection of clinical data and tumor tissue removed during brain surgeries for future research. | Procedure: Tissue Bank<br>* Collection of clinical data and tumor tissue.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Collect and maintain clinical data and tumor tissue removed during brain surgeries. |  | 10 Years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Brain Neoplasms, Central Nervous System Diseases, Central Nervous System Neoplasms, Brain Diseases, Nervous System Neoplasms
Studying DNA in Samples From Younger Patients With Down Syndrome and Acute Myeloid Leukemia Treated on COG-AAML0431 Clinical Trial

Study Overview
=================
Brief Summary
-----------------
RATIONALE: Studying samples of blood, tissue, and bone marrow from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This research trial studies DNA samples from patients with Down syndrome and acute myeloid leukemia treated on COG-AAML0431 clinical trial.

Detailed Description
-----------------
OBJECTIVES: To identify new genetic abnormalities associated with acute myeloid leukemia (AML) in patients with Down syndrome through whole-genome sequencing. OUTLINE: This is a multicenter study. Extracted DNA and RNA from cryopreserved specimens are analyzed for genomic sequencing, gene mutation, and microarray analysis.

Official Title
-----------------
Whole Exon Sequencing of Down Syndrome Acute Myeloid Leukemia

Conditions
-----------------
Leukemia

Intervention / Treatment
-----------------
* Genetic: gene mapping
* Genetic: microarray analysis
* Genetic: mutation analysis
* Genetic: nucleic acid sequencing
* Other: laboratory biomarker analysis


Participation Criteria
=================
Eligibility Criteria
-----------------
DISEASE CHARACTERISTICS: Down syndrome children diagnosed with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS) Clinical samples from patients enrolled on the Children's Oncology Group (COG) AAML0431 phase III clinical trial, and from the Children's Hospital of Michigan Cell Bank Diagnostic blast samples and matched remission samples PATIENT CHARACTERISTICS: Not specified PRIOR CONCURRENT THERAPY: Not specified

Ages Eligible for Study
-----------------
Maximum Age: 3 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Genetic: gene mapping|nan|
|Genetic: microarray analysis|nan|
|Genetic: mutation analysis|nan|
|Genetic: nucleic acid sequencing|nan|
|Other: laboratory biomarker analysis|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Identification of unique mutations through whole-genome sequencing |  |  | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
childhood myelodysplastic syndromes, childhood acute myeloid leukemia/other myeloid malignancies, childhood acute megakaryocytic leukemia (M7)
The Influence of Different Factors on Workers' Disability Due to Low Back Pain

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to determine, in Spanish workers, the influence of different factors (personal, psychological, work related and clinical) on the risk of being on sick leave during the 18 months after baseline assessment, and on the duration of that sick leave.

Official Title
-----------------
Study to Identify the Influence of Different Factors on Workers' Disability Due to Low Back Pain

Conditions
-----------------
Low Back Pain

Intervention / Treatment
-----------------
* Behavioral: Set of questionnaires (respondent)


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Subjects who get their checkups at participating health services With a labor contract that won't make it likely that they stop work before the next 18 months, for causes other than their health Who sign the informed consent form Exclusion Criteria: Don't sign the informed consent form Inability to fill our the questionnaires Bedridden Rheumatologic inflammatory disease, cancer or fibromyalgia Suspicion of fibromyalgia Red flags for systemic disease Criteria for surgery Criteria for urgent referral to surgery

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| A<br>Workers from companies and workers' health care organizations who go for their periodic medical checkup. | Behavioral: Set of questionnaires (respondent)<br>* A set of questionnaires to determine risk factors for sick leave due to low back pain.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The influence of different factors on risk of sick leave for low back pain |  | 18 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
low back pain, workers, disability, sick leave
Study 3 Learning Verbs and Pronouns

Study Overview
=================
Brief Summary
-----------------
The goal of this research is to explore abilities to learn word meanings from overheard conversations in children with ASD (and, as a control, typically developing children). Specific Aim 3 (Experiment 3): Determine whether children with ASD can learn verbs and pronouns by overhearing. Most prior work on learning from overheard speech has focused on learning nouns that label objects. This experiment extends this work to study other kinds of words.

Official Title
-----------------
Study 3 Learning Verbs and Pronouns

Conditions
-----------------
Autism Spectrum Disorder

Intervention / Treatment
-----------------
* Behavioral: Addressed Speech
* Behavioral: Overheard Speech


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: children with or without a diagnosis of ASD between 24 to 71 months of age minimum language and nonverbal cognition age of 24 months Exclusion Criteria: native language is not English born premature (< 36 weeks) has uncorrected hearing or vision impairments has developmental disorders or medical conditions other than ASD that affect language or cognition (excepting psychiatric conditions often comorbid with ASD such as ADHD) has a history of photosensitive epileptic seizures

Ages Eligible for Study
-----------------
Minimum Age: 24 Months
Maximum Age: 71 Months

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Basic Science
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Addressed<br>Children participate in an interaction with an experimenter who uses the word to be learned. | Behavioral: Addressed Speech<br>* New words are introduced directly to the child by an experimenter.<br>|
| Experimental: Overheard<br>Children are present in the room while an experimenter uses the word to be learned in an interaction with another experimenter. | Behavioral: Overheard Speech<br>* New words are introduced with the child as a bystander rather directly taught.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Object selection | The first object that children touch after being prompted. | During test phase of the experimental session (e.g., within 5 seconds) |
Dynamic Hyperinflation In Mechanically Ventilated Chronic Obstructive Pulmonary Disease Patients

Study Overview
=================
Brief Summary
-----------------
Chronic obstructive pulmonary disease is a common respiratory condition that is characterized by inflammation of the large and small peripheral airways , the alveoli and adjacent capillary networks. Severe airflow obstruction that imposes a significant load on the respiratory system is a major manifestation of Chronic obstructive pulmonary disease. The reduced expiratory airflow also causes air trapping at the end of expiration , producing alveolar pressure that are higher than atmospheric pressure before the next breath. This condition is intrinsic positive end-expiratory pressure .

Official Title
-----------------
Evaluation Of Dynamic Hyperinflation In Mechanically Ventilated Chronic Obstructive Pulmonary Disease Patients

Conditions
-----------------
Pulmonary Disease, Chronic Obstructive

Intervention / Treatment
-----------------
* Device: Mechanical ventilator


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patient with acute exacerbation of Chronic obstructive pulmonary disease and respiratory failure who are intubated and mechanically ventilated. Exclusion Criteria: patient with neuromuscular diseases. patient with pulmonary vascular diseases e.g pulmonary embolism.
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Intrinsic positive end expiratory pressure > 5<br>chronic obstructive pulmonary disease patient with intrinsic positive end expiratory pressure more than5 | Device: Mechanical ventilator<br>* Mechanical ventilation, in the healthcare setting or home, helps patients breathe by assisting the inhalation of oxygen into the lungs and the exhalation of carbon dioxide. Depending on the patient's condition, mechanical ventilation can help support or completely control breathing.<br>|
| Auto positive end expiratory pressure < 5<br>chronic obstructive pulmonary disease patient with intrinsic positive end expiratory pressure less than5 | Device: Mechanical ventilator<br>* Mechanical ventilation, in the healthcare setting or home, helps patients breathe by assisting the inhalation of oxygen into the lungs and the exhalation of carbon dioxide. Depending on the patient's condition, mechanical ventilation can help support or completely control breathing.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The duration of mechanical ventilation |  | 1 month |
Evaluation of Functional and Social Changes After Bariatric Surgery

Study Overview
=================
Brief Summary
-----------------
After bariatric surgery there are big changes in the daily functions, activities and social participation of the patients. This is a prospective study that examine daily performance and daily participation by questionnaires, before and after bariatric surgery.

Official Title
-----------------
Evaluation of Functional and Social Changes After Bariatric Surgery

Conditions
-----------------
Functional and Social Performance

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Overweight patients who are fit for surgery . Exclusion Criteria: Children, Neurological patients, amputations

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The change of participation before and after surgery |  | the patient will answer the questionnaire before and after (3 months, 6 months) surgery. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| sexuality questionnaire |  | the patient will answer the questionnaire before and after (3 months, 6 months) surgery. | 
| activity daily questionnaire |  | the patient will answer the questionnaire before and after (3 months, 6 months) surgery. | 
| range of motion (flexion of knee and thigh in degrees) |  | measure will be taken before and after (3 months, 6 months) surgery. | 
| circumferences mesurement (knee, thigh and waist) in centimeters |  | measure will be taken before and after (3 months, 6 months) surgery. | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
ADL, Bariatric surgery, Daily participation
The Preemptive Analgetic Potency of Low Dose S-Ketamine

Study Overview
=================
Brief Summary
-----------------
The primary hypothesis is improved postoperative analgetic quality using S-Ketamine, particularly in patients suffering from chronic pain.

Detailed Description
-----------------
The investigators are dealing mainly with the finding of the right dosage for the optimal safety and efficacy of S-Ketamine, but also discovering new possible areas of investigation (e.g. anti-depressive effect, anti-neuropathic effect).

Official Title
-----------------
The Opioid Sparing Effect of Minimal Dose S-Ketamine Applied as a Coanalgesic During the Perioperative Period - An Active Placebo-Controlled, Double Blinded, Randomized Clinical Trial (МiniKet)

Conditions
-----------------
Pain

Intervention / Treatment
-----------------
* Drug: S-Ketamine
* Other: Placebo Comparison


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Scheduled for major abdominal surgery Suitable for PCA Cardio-vascular stable Age: 18+ Between 50-120kg BW ASA 1-3 Good Compliance for pain monitoring Exclusion Criteria: Allergy to S-Ketamine Severe liver or kidney dysfunction Severe coronary disease Pregnancy Present or past psychotic disorders Addiction to alcohol or opioids Poor compliance

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Placebo Comparator: Placebo<br>Placebo as saline solution | Other: Placebo Comparison<br>* saline control<br>* Other names: Placebo;|
| Experimental: Low dose<br>S-Ketamine | Drug: S-Ketamine<br>* drug<br>* Other names: Ketanest;|
| Active Comparator: High dose<br> | Drug: S-Ketamine<br>* drug<br>* Other names: Ketanest;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| postoperative opioid consumption |  | 1 year |