Steroid Injection for the Treatment of Greater Trochanteric Pain Syndrome

Study Overview
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Brief Summary
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The objective of this study is to conduct a randomized, single-blinded placebo controlled trial comparing two modalities for the treatment of pain and mobility associated with trochanteric bursitis: (1) injection of glucocorticosteroid and local anesthetic, (2) injection of local anesthetic. We hope to determine whether steroid injections provide a statistically significant improvement in pain symptoms and hip mobility in subjects with trochanteric bursitis, as compared to an injection of local anesthetic. Our null hypothesis is that no statistically significant difference exists between the two treatment modalities.

Detailed Description
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Trochanteric bursitis is an inflammation of the bursal sac overlying the greater trochanter of the femur. The etiology of this disease is unknown, but it is clinically characterized by chronic aching pain over the lateral aspect of the hip, which can be exacerbated by certain movements such as external rotation and abduction (2). In order to objectively determine the level of pain and mobility associated with trochanteric bursitis, some orthopaedic surgeons use scoring systems (a qualitative and quantitative scoring test) to assess patients (4). In our practice, trochanteric bursitis has been treated by injection of glucocorticosteroids (steroids) combined with local anesthetic at the site of the greater trochanter (1). Additionally, it has been found that increasing steroid dosage provides a greater level of relief (3). Although steroids are usually an effective treatment, no studies to date have compared steroid injections for relief of trochanteric bursitis pain and mobility versus a placebo injection or local anesthetic injection alone.

Official Title
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Steroid Injection for the Treatment of Greater Trochanteric Pain Syndrome: A Randomized Controlled Trial

Conditions
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Bursitis

Intervention / Treatment
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* Drug: Depomedrol injection
* Drug: Lidocaine, Marcaine


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adult patients with tenderness at the greater trochanter Exclusion Criteria: Subjects < 17 years of age Subjects with previous surgery to the greater trochanter Subjects allergic to Lidocaine, Marcaine, or Depomedrol

Ages Eligible for Study
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Minimum Age: 17 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 1<br>1cc Depomedrol, 4 cc 1% Lidocaine, 4 cc 0.25% Marcaine | Drug: Depomedrol injection<br>* 1 cc of Depomedrol 80<br>|
| Placebo Comparator: 2<br>4 cc 1% Lidocaine, 4 cc 0.25% Marcaine | Drug: Lidocaine, Marcaine<br>* 4 cc of each local anesthetic<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| WOMAC hip score |  | 2 weeks, 6 weeks, 3 months |