Risk Factors of Complications Regarding Patients Undergoing Brain Tumour Neuro-surgery (Cranioscore).

Study Overview
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Brief Summary
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Patients undergoing a brain tumour neurosurgery with craniotomy may present rare but lifethreatening post-operative complications. There are currently no strong recommendations to help the clinician in an attempt to properly hospitalise these patients after their intervention (Neuro-ICU, ICU,surgical ward). Determining risk factors of post-operative complications could optimise resources. Therefore hospitalisation in Neuro-ICU would be mandatory in only a little number of patients.

Detailed Description
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Retrospective analysis of a prospective database to create a Risk Score. Post-operative neurosurgery complications recording (Hyponatremia < 135mmol/l,Insulin administration, Nausea-Vomiting, Glasgow Coma Score, Inhalation, Post-operative intra-cranial bleeding requiring neurosurgery, Intra-cranial hypertension, Use of osmotherapy, Status epilepticus, Brain death, Death). Collection of datas as Duration of mechanical ventilation, Length of ICU stay, Length of hospital stay. Validation of this score on an independent prospective cohort.

Official Title
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Observational Study of Risk Factors of Neuro-critical Care Complications Regarding Patients Undergoing Brain Tumour Neuro-surgery : a Prospective Validation of the Cranioscore.

Conditions
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Neuro-surgery, Brain Tumor, Post-operative Complications, Neuro-ICU Stay

Intervention / Treatment
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* Other: Collecting pre-operative, per-operative data, neuro-radiological data and post-operative neuro-surgery complications


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients undergoing neuro-surgery for a brain tumor Exclusion Criteria: Neuro-surgical emergency

Ages Eligible for Study
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Minimum Age: 15 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Neurosurgery for brain tumor patients<br>Collecting pre-operative and per-operative data, neuro-radiological data and post-operative complications | Other: Collecting pre-operative, per-operative data, neuro-radiological data and post-operative neuro-surgery complications<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Post-operative complications requiring Neuro-ICU stay ≥ 24 hours after surgery for neurosurgical reason. |  | During ICU stay, average of 24 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Describing post-operative complications in patients undergoing neuro-surgery for brain tumor. | Hyponatremia < 135mmol/l,Insulin administration, Nausea-Vomiting, Glasgow Coma Score, Inhalation, Post-operative intra-cranial bleeding requiring neurosurgery Intra-cranial hypertension, Use of osmotherapy, Status epilepticus, Brain death Death. | During ICU stay, average of 24 hours | 
| Duration of mechanical ventilation |  | Duration of mechinal ventilation, average of 12 hours | 
| Length of ICU stay |  | Duration of ICU stay, average of 24 hours | 
| Length of hospital stay |  | Duration of hospital stay, expected average 5 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Neuro-ICU resources, Neuro-surgery, Post-operative complications