PC in Stance and During Functional Mobility Following BIG for PD

Study Overview
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Brief Summary
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LSVT BIG is an intensive, amplitude based rehabilitation program that has been demonstrated to improve one of the hallmark features of Parkinson's disease, specifically bradykinesia. We are interested in knowing the effects of this therapeutic approach on postural control and gait parameters.

Detailed Description
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LSVT BIG is an intensive, amplitude based rehabilitation program that has been demonstrated to improve one of the hallmark features of Parkinson's disease, specifically bradykinesia. Postural instability and gait disturbance is another debilitating feature of Parkinson's disease. While LSVT BIG targets postural correction through exercises which challenge balance, the effect of this intervention on stability margins and functional balance assessments have not been well established in the literature. This study includes outcome measures not previously examined with this intervention and may provide valuable evidence regarding the impact of this intervention on postural control, balance and falls risk. Alternative amplitude programs have also been designed to meet the needs of patients with PD. These programs adjust frequencies for patients and individualize sessions more than LSVT BIG. We are interested in knowing if these alternative frequencies and amplitude approaches are similarly as effective as LSVT BIG in our outcome measures.

Official Title
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Postural Control in Stance and During Functional Mobility Following Management of Parkinson's Disease With LSVT BIG Training

Conditions
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Parkinson Disease

Intervention / Treatment
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* Behavioral: LSVT BIG


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Subjects will be included in the study if they have been diagnosed with idiopathic Parkinson's disease and are English speaking. Exclusion Criteria: Exclusion Criteria: 1) previous completion of LSVT BIG or other formal amplitude program training 2) non-idopathic Parkinsonism 3) any medical condition that would contraindicate exercise (ie. unstable cardiovascular disease) 4) cognitive impairment that limits ability to follow direction or demonstration
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Effect of LSVT BIG therapy on Postural Control and Gait Parameters<br>LSVT BIG is a commonly used protocol to manage functional movement for those with Parkinson's Disease. This study measured postural control and gait parameters following a 4-week course of LSVT BIG therapy. | Behavioral: LSVT BIG<br>* LSVT BIG is a 4-week program that focuses on movement recalibration for people with a diagnosis of Parkinson's disease.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mini Balance Evaluation Systems Test (Mini-BESTest) | A change in reactive, proactive, and sensory contributions to postural control (balance) is assessed. | Pre-Intervention (baseline) and Post-Intervention (week 5) | 
| Fullerton Advanced Balance Scale (FAB) | A change in higher level assessment of postural control is assessed. | Pre-Intervention (baseline) and Post-Intervention (week 5) | 
| Functional and Multidirectional Reach Tests | A change in proactive postural control strategies is assessed. | Pre-Intervention (baseline) and Post-Intervention (week 5) | 
| Center of Pressure measures (digitized walkway) | A change in the limits of stability is assessed. | Pre-Intervention (baseline) and Post-Intervention (week 5) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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postural control, gait