Histologic Evaluation of Bone Formation After Alveolar Augmentation by Sandwich Osteotomy Procedure for Dental Implants Insertion

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to evaluate histologic bone remodeling after interpositional bone graft (sandwich osteotomy technique) using xenograft to fill the gap of the bone after moving and fixation it in the proper place.

Detailed Description
-----------------
Dental implant use for partially edentolous jaw is a predictable procedure with high success rate. However, implantation procedure requires sufficient bone support both vertically and horizontally, and sometimes there is bone defect that requires bone augmentation prior to dental implant insertion. There are some bone augmentation techniques known and used for this purposes, including: guided bone regeneration (GBR), distraction osteogenesis, split osteotomy, onlay bone graft, and interpositional bone graft. One of the techniques is the interpositional bone graft using sandwich osteotomy technique, in which a cut is made in the bone (one horizontal and two vertical) separating a mobile bone portion which is fixed (using bone plate) in its new ideal position. The gap between the moved bone and the remaining bone is filled with xenograft (bio-oss). There is no documentation in the literature about histological evaluation of the bone after this well known clinical procedure. Four months after the bone augmentation procedure - the fixating plate is moved out and dental implants inserted. The first bur of the implantation (the smallest in the diameter) will be a trephine from which a histologic slide will be taken for check. The continuous dental implants insertion is the normal protocol for dental implantation (widening the recipient hole with bur, and insertion of the implant), followed by rehabilitation by prosthodontics.

Official Title
-----------------
Sandwich Osteotomy Histologic Evaluation

Conditions
-----------------
Dental Implants

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: age > 18 years partially edentulous patients insufficient bone height (recipient site) interested in fixed dental rehabilitation using dental implants Exclusion Criteria: smoking unbalanced diabetes

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| partially edentulous patients<br>Adult (post growth period) patients who are interested in fixed dental rehabilitation (non- removable denture) by dental implants. Partially edentulous patients with insufficient bone height for dental implant insertion. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Histologic slide evaluation of the bone on the dental implantation time |  | implantation day (four months post bone augmentation) | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
fixed dental rehabilitation, insufficient bone height, Partially edentulous patients, Patients interested in fixed non removable dental rehabilitation by dental implants., The recipient bone with insufficient bone height for dental implant insertion., Adult patients, edentulous