Active Induction of Labor in Pregnancies Complicated With Oligohydramnios at Term

Study Overview
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Brief Summary
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The purpose of this study is to evaluate the risk of cesarean delivery in pregnancies complicated with isolated oligohydramnios managed by induction of labor. This prospective case-control study was conducted in Hamıdıye Sisli Etfal Teaching and Research Hospital between January 2013 and June 2014. 159 women with isolated oligohydramnios and 165 women with postdate pregnancies who met the inclusion criteria underwent induction of labor with dinoprostone or oxytocin. The rate and the indications of C/S deliveries were compared between two groups.

Detailed Description
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The study was designed as a prospective study. The rates of cesarean section and maternal/fetal outcomes had been compared between pregnancies complicated with isolated oligohydramnios at term and postdate pregnancies. All patients with isolated oligohydramnios were term (37-40 weeks' gestation according to accurate last menstrual period and first trimester sonographic examination). Oligohydramnios was defined as an amniotic fluid index < 5 cm. The control group consisted of prolonged pregnancies in the absence of spontaneous labor and oligohydramnios. Prolonged pregnancy is diagnosed if 41 gestational weeks are completed according to accurate date of last menstrual period and first trimester ultrasound. All patients who accepted to join the study gave informed consent. All patients had a complete physical and obstetrical examination. Vital signs were recorded at regular intervals. The primary outcome measure was defined as cesarean section rates in pregnancies complicated with isolated oligohydramnios managed by induction of labor.

Official Title
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Management of Active Induction of Labor in Pregnancies Complicated With Oligohydramnios at Term; the Mode of Delivery and the Neonatal Outcomes

Conditions
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Oligohydramnios

Intervention / Treatment
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* Other: normal delivery tracking


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: term isolated oligohydramnios postdate pregnancies vertex presentation singleton pregnancies primigravid and multigravid women Exclusion Criteria: women with presence of any chronic disease maternal condition complicating the pregnancy

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 44 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| term isolated oligohydramnios<br>Labor Monitoring and normal delivery tracking | Other: normal delivery tracking<br>* normal delivery tracking<br>|
| prolonged pregnancies<br>Labor Monitoring and normal delivery tracking | Other: normal delivery tracking<br>* normal delivery tracking<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cesarean rates in pregnancies complicated with isolated oligohydramnios |  | up to 18 month | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Fetal distress rates |  | up to 18 month | 
| Number of patients (fetus) with 5-min Apgar score < 7 |  | up to 18 month | 
| Number of patients with meconium stained amniotic fluid |  | up to 18 month | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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induction, cesarean delivery