Aromatherapy Massage for Itching Management in Liver Diseases

Study Overview
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Brief Summary
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The aim of this study is to determine the effect of aromatherapy massage on itching, comfort, skin pH level and skin moisture in individuals with liver disease. Research Hypotheses: H1: Aromatherapy massage has an effect on the level of itching in individuals with itchy liver disease. H2: Aromatherapy massage has an effect on the general comfort level in individuals with itchy liver disease, H3: Aromatherapy massage has an effect on skin pH level in individuals with itchy liver disease. H4: Aromatherapy massage has an effect on skin moisture in individuals with itchy liver disease.

Official Title
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The Effect of Aromatherapy Massage on Itching, Comfort, Skin pH Level, and Skin Moisture in Liver Diseases: Randomised Controlled Trial

Conditions
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Aromatherapy, Massage, Liver Diseases, Itching, pH Level, Skin Moisture

Intervention / Treatment
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* Other: aromatherapy massage (diluted tea tree oil)
* Other: aromatherapy massage (sweet almond oil)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients who volunteered to participate in the study, with a diagnosis of chronic liver disease (liver cirrhosis (primary biliary cirrhosis, alcoholic, cardiac, post-necrotic, cryptogenic cirrhosis, Wilson's Cirrhosis, hemochromatosis), chronic viral hepatitis), had no cognitive impairment, were not included in the pre-application, could answer questions, itch score of above 3 (with Visual Analogue Scale). Exclusion Criteria: patients are taking antipruritic treatment, have itchy skin disease before, ulcer, eczema, etc. in the area to be applied patients with dermatological problems, any swelling or signs of inflammation in the area ---to be treated, neuropathy or loss of sensation in the area to be treated patients with allergic to tea tree oil, perfume, or cosmetics, diagnosed with cancer

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: aromatherapy<br>In addition to routine medical treatment, massage with diluted tea tree oil was applied to the individuals in this group. | Other: aromatherapy massage (diluted tea tree oil)<br>* massage with diluted tea tree oil was applied<br>|
| Placebo Comparator: placebo<br>Individuals in this group were provided massage with sweet almond oil in addition to routine medical treatment. | Other: aromatherapy massage (sweet almond oil)<br>* massage with sweet almond oil was applied<br>|
| No Intervention: control<br>Individuals in this group received only routine medical treatment. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Itching | Itching was assessed with the 5D Itch Scale. The total score of the scale ranges from 5 to 25, with 5 points indicating the absence of itching and 25 points indicating the highest severity of itching. | Day 1 | 
| Itching | Itching was assessed with the 5D Itch Scale. The total score of the scale ranges from 5 to 25, with 5 points indicating the absence of itching and 25 points indicating the highest severity of itching. | Day 14 | 
| comfort | Comfort assessed with the General Comfort Scale. The score to be obtained from the scale varies between 48 and 192. 48 points indicating the low comfort level and 192 points indicating the high comfort level. | Day 1 | 
| comfort | Comfort assessed with the General Comfort Scale.The score to be obtained from the scale varies between 48 and 192. 48 points indicating the low comfort level and 192 points indicating the high comfort level. | Day 2 | 
| comfort | Comfort assessed with the General Comfort Scale. The score to be obtained from the scale varies between 48 and 192. 48 points indicating the low comfort level and 192 points indicating the high comfort level. | Day 14 | 
| skin pH level | For pH level measurement, the F-74 G model skin pH measuring device manufactured by HORIBA Scientific and ISFET (Ion Sensitive Field Effect Transistor) 0040-10D model pH electrode produced by HORIBA Scientific were used. | Day 1 | 
| skin pH level | For pH level measurement, the F-74 G model skin pH measuring device manufactured by HORIBA Scientific and ISFET (Ion Sensitive Field Effect Transistor) 0040-10D model pH electrode produced by HORIBA Scientific were used. | Day 2 | 
| skin pH level | For pH level measurement, the F-74 G model skin pH measuring device manufactured by HORIBA Scientific and ISFET (Ion Sensitive Field Effect Transistor) 0040-10D model pH electrode produced by HORIBA Scientific were used. | Day 14 | 
| skin moisture level | DMM brand skin moisture measuring device was used to measure skin moisture level. | Day 1 | 
| skin moisture level | DMM brand skin moisture measuring device was used to measure skin moisture level. | Day 2 | 
| skin moisture level | DMM brand skin moisture measuring device was used to measure skin moisture level. | Day 14 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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aromatherapy, massage, liver Diseases, itching