Effects of High-intensity Interval Aerobic Training on Balance, Walking Capacity, and Quality of Life in Patients With Sub-acute Stroke

Study Overview
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Brief Summary
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Hemiplegia is one of the most common sequelae of stroke. Stroke is the leading cause of disability in adults all around the world. Stroke survivors can suffer several neurological impairments and deficits which have an important impact on patient's quality of life and which increase the costs for health and social services. After stroke, impairments in ADLs and functional status, deterioration in health related quality of life can be seen. The purpose of this study is to Determine the effect of Aerobic exercise training on Balance, Walking capacity and quality of life in sub-acute stroke.

Official Title
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Effects of High-intensity Interval Aerobic Training on Balance, Walking Capacity, and Quality of Life in Patients With Sub-acute Stroke

Conditions
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Stroke, Ischemic, Cerebrovascular Accident

Intervention / Treatment
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* Other: High intensity Interval Training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 18 to 75 years of age. Ischemic Stroke that occurred in the recent 3 months. Who can walk independently or by using assistive device. Have a minimum Chedoke McMaster Stroke Assessment (CMSA) leg impairment score of 3 but less than 7. Exclusion Criteria: Patients were excluded from the study if they have a stroke that occurs more than 3 months. Hemorrhagic Stroke. If resting blood pressure more than 160/100 even after taking medications Have by-pass surgery in recent 3 months. Other musculoskeletal problems which restrict the patient's ability to do aerobic activity.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Conventional Rehabilitation<br>Based on the functional capacity of each participant, customized Aerobic exercise plan was designed by the on-site physiotherapist. | Other: High intensity Interval Training<br>* All the participants underwent 5 weeks of High intensity interval training.<br>|
| Experimental: Combined Training (conventional rehabilitation plus high-intensity interval training):<br>The patients received 40 minutes of High intensity interval treadmill training in addition to their normal conventional rehabilitation. | Other: High intensity Interval Training<br>* All the participants underwent 5 weeks of High intensity interval training.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 6 Minute walk Test | To determine the cardiorespiratory fitness of individual after sub-acute stroke. | 5 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Berg Balance test and rating scale | The scale is used to determine the Balance and stability of patient. Total score of the scale is 56. A score of < 45 indicates individuals may be at greater risk of falling. | 5 weeks | 
| Stroke Impact scale | The scale is used to measure the impairment and quality of life after stroke. The scale consists of 8 domains. In this study, only 4 domains related to hand function ,strength, mobility and Activity of daily living were used.The maximum score is 140. | 5 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Cerebrovascular accident, Treadmill Training, High-intensity interval training, Walking capacity.