Neuropathic Pain Database

Study Overview
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Brief Summary
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To establish the infrastructure for a national neuropathic pain database. To determine the longterm outcome of the management of chronic neuropathic pain including pain relief, disability, and quality of life.

Detailed Description
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The database will provide standard information on demographics, diagnosis, treatment interventions and outcome modeled on guidelines from the expert panel on initiatives on Methods, Measurement and Pain Assessment in Clinical Trials (IMMPACT)(Turk et al.,Pain 2003;106:337-345) The IMMPACT panel determined that patients should be evaluated according to six core domains as follows: Pain, physical functioning, emotional functioning, subject rating of global satisfaction with treatment, symptoms and adverse events and subject disposition. The database will allow us to examine outcomes based on single (eg. pregabalin) and multiple (e.g tricyclic antidepressants and gabalin) therapeutic interventions. Standard guidelines for management of neuropathic pain acknowledge that polypharmacy is appropriate when individual first line treatments fail to provide adequate pain relief (Gilron I et al., CMAJ 2006; 175: 265-275; Attal N et al., European Journal of Neurology 2006; 13: 1153-1169)

Official Title
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National Neuropathic Pain Database Study

Conditions
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Neuropathic Pain

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Primarily Neuropathic Pain Able to give informed consent Estimated Life Expectancy of 2 years Exclusion Criteria: Not primarily neuropathic pain Declined participation- too much traveling Declined participation- Unknown Declined participation- Other, specify Considered unreliable- personality disorder Considered unreliable- cognitive impairment Considered unreliable- substance abuse Considered unreliable- Other Language barrier Exceeded quarterly quota Presentation with progressive or recurrent cancer, fibromyalgia, perineal pain of unknown etiology Other, specify
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| 1<br>New patients with a diagnosis of Neuropathic Pain | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To establish the infrastructure for a national Neuropathic Pain Database. | To establish the infrastructure for a National Neuropathic Pain Database, with a composite primary outcome measure in average pain intensity (based on average pain intensity of BPI) and reduction in disability (based on Interference Scale Score of BPI)) | 2 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To determine the longterm outcome of the management of chronic neuropathic pain including pain relief, disability and quality of life. |  | 2 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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neuropathic pain, database, prospective, national