Prevalence of Wound Healing Disturbances in Geriatric Inpatients (WONDER Study)

Study Overview
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Brief Summary
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In geriatric patients, there is a plethora of nutritional and illness-related parameters, resulting in a complex situation which hampers identification of risk factors.In the planned prospective study, the point and period prevalence of wound healing disorders (WHD) is examined at admission and at discharge in a cohort of 517 male and female geriatric patients. As the investigators are also interested to study the occurrence of WHD in patients with malnutrition (and other geriatric phenomena) compared to the prevalence of WHD in patients with a good nutritional Status.

Detailed Description
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The investigators will determine the prevalence of impaired wound healing upon admission to the hospital as well as the incidence of new wound healing disorders during hospital stay with specific focus on malnutrition and other important nutritional parameters in geriatric patients. Therefore the investigators intend to study consecutively admitted patients both at admission and at discharge and monitor them during hospital stay. The investigators will investigate the associations between the individual nutritional status and body composition parameters (such as sarcopenia) and WHD in geriatric patients, taking both medical variables and the frailty syndrome into account.

Official Title
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Prevalence of Wound Healing Disturbances in Geriatric Inpatients With Specific Focus on Malnutrition, Other Nutritional Parameters and the Frailty Syndrome (WONDER Study)

Conditions
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Wound Healing Disorder, Malnutrition

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age ≥ 60 years Informed written consent Normal cognitive status according to Mini-Mental State Examination (MMSE ≥ 24 points) Life expectancy of > 3 months according to treating doctor Proficient in German Exclusion Criteria: Lack or incapacity of informed consent MMSE < 24 Life expectancy < 3 months according to assessment by the attending physician Short term patients (< 3 days of hospital stay) Lack of German language

Ages Eligible for Study
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Minimum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prevalence of wound healing disturbances | Number of wound healing disturbances upon admission to the hospital in General | Baseline | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Nutritional Parameter | Mini Nutritional Assessment - Short Form (questionnaire) | Baseline and up to 3 weeks | 
| Functional Parameter | Timed Up & Go Test | Baseline and up to 3 weeks | 
| Functional Parameter | 4m-walk Test to measure gait speed | Baseline and up to 3 weeks | 
| Functional Parameter | Lung Test to measure respiratory force | Baseline and up to 3 weeks | 
| Strength Parameter | Hand grip strength | Baseline and up to 3 weeks | 
| Strength Parameter | Knee extension strength | Baseline and up to 3 weeks | 
| Frailty | Frailty Status according to Fried criteria | Baseline and up to 3 weeks | 
| Index of quality of life | EQ-5D-5L (questionnaire) to measure quality of life | Baseline and up to 3 weeks, after 3 months and after 6 months | 
| Body composition | Bioelectric impedance analysis | Baseline and up to 3 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Geriatrics, Frailty