Infantile Hemangioma With Minimal or Arrested Growth : Epidemiology, Clinical Characteristics and Evolution

Study Overview
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Brief Summary
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Infantile hemangioma (IH) is the most common vascular tumor of infancy, characterized by its clinical history. Absent at birth or present under the form of a premonitory mark, they display a rapid proliferative phase starting in the first weeks of life. Then, after a plateau phase, they slowly involute. However, a subtype of IH named abortive, minimal or arrested growth, reticular or telangiectatic hemangioma differs from typical IH because it doesn't have a proliferative component, or only a minimal one. This subtype of hemangioma has been recently described and data are lacking regarding its proportion among infantile hemangioma and its differences with classic infantile hemangioma. The aim of this study is to estimate the proportion of abortive hemangioma among infantile hemangioma. Also, the investigators aim to compare the clinical characteristics of classic infantile hemangiomas and abortive hemangiomas. Lastly, investigators wished to study the evolution of abortive hemangioma.

Official Title
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Comparing Epidemiological and Clinical Characteristics of Infantile Hemangioma With Minimal or Arrested Growth (IH-MAG) and Classic Infantile Hemangioma : a Retrospective Study

Conditions
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Hemangioma, Capillary

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Children between 0 and 18 years old Followed in the dermatology department of CHRU de Nancy between January 2014 and December 2020 Presenting with one or more infantile hemangioma Exclusion Criteria: - Those whoes guardian does not want his data to be collected in this study

Ages Eligible for Study
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Minimum Age: 1 Day
Maximum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Infantile hemangioma with minimal or arrested growth<br>Epidemiological and clinical characteristics of infantile hemangioma with minimal or arrested growth. | |
| Classic infantile hemangioma<br>Epidemiological and clinical characteristics of classic infantile hemangioma. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Proportion of abortive hemangioma among infantile hemangioma | Proportion of abortive hemangioma among infantile hemangioma | baseline | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To compare the epidemiological characteristics between infantile hemangioma and abortive hemangioma : sex | Compare sex predominance between infantile hemangioma and abortive hemangioma | baseline | 
| To compare the epidemiological characteristics between infantile hemangiomas and abortive hemangiomas : prematurity | Compare prematurity rates between infantile hemangiomas and abortive hemangiomas | baseline | 
| To compare the epidemiological characteristics between infantile hemangiomas and abortive hemangiomas : birthweight | Compare birthweight between infantile hemangiomas and abortive hemangiomas | baseline | 
| To compare the clinical characteristics between infantile hemangiomas and abortive hemangiomas : localization | Compare localization between infantile hemangiomas and abortive hemangiomas | baseline | 
| To compare the clinical characteristics between infantile hemangiomas and abortive hemangiomas : treatment | le hemangiomas and abortive hemangiomaCompare treatment between infanti | baseline | 
| To compare the clinical characteristics between infantile hemangiomas and abortive hemangiomas : complications | Compare complications between infantile hemangiomas and abortive hemangioma | baseline | 
| To compare the clinical characteristics between infantile hemangiomas and abortive hemangiomas : size | Compare size (focal, extended or segmental) between infantile hemangiomas and abortive hemangioma | baseline | 
| To study the evolution of abortive hemangioma : erythematous macule | Evaluation of the fading of erythematous macule between the stage of maximal proliferation and the last follow-up | through study completion, an average of 4 years | 
| To study the evolution of abortive hemangioma : papules of proliferation | Evaluation of the regression of the papules of proliferation between the stage of maximal proliferation and the last follow-up | through study completion, an average of 4 years | 
| To study the evolution of abortive hemangioma : telangiectasias | Evaluation of the fading of telangiectasias between the stage of maximal proliferation and the last follow-up | through study completion, an average of 4 years | 
| To study the evolution of abortive hemangioma : halo of vasoconstriction | Evaluation of the fading of the vasoconstricted halo between the stage of maximal proliferation and the last follow-up | through study completion, an average of 4 years | 
| To study the evolution of abortive hemangioma : areas of vasoconstriction | Evaluation of the fading of vasoconstricted areas between the stage of maximal proliferation and the last follow-up | through study completion, an average of 4 years | 
| To study the evolution of abortive hemangioma : dilated veins | Evaluation of the fading of dilated veins between the stage of maximal proliferation and the last follow-up | through study completion, an average of 4 years |