Promoting In-Home Activities at a Memory & Aging Clinic

Study Overview
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Brief Summary
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The objective of the proposed study, Promoting In-Home Activities at a Memory & Aging Clinic (Pro-Home MeC), is to assess and improve the feasibility of a physical activity (PA) intervention and the measurement of cognitive outcomes in a memory clinic setting for inactive older adults with mild cognitive impairment (MCI) or mild dementia and to examine how and improve the feasibility and acceptability of the procedures.

Official Title
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Promoting In-Home Activities at a Memory & Aging Clinic (Pro-Home MeC)

Conditions
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MCI, Mild Dementia

Intervention / Treatment
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* Behavioral: Gentle Moves


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 50+ Fluent in English Diagnosed with MCI or mild dementia Physically inactive (< 150 min/wk of planned PA) Able to sit in a chair independently for 15+ minutes Exclusion Criteria: Have significant mental or physical disabilities that lead to inability to perform PA safely (e.g., major stroke) Severe uncompensated hearing or visual loss Having insufficient decisional capacity to consent to participate in research. Lack of safety awareness Unwilling to be assigned to Pro-Home MeC or control group Currently participating in PA intervention research

Ages Eligible for Study
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Minimum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Gentle Moves<br>Three-month physical activity intervention. | Behavioral: Gentle Moves<br>* A safe physical activity program which consists of a brief motivational enhancement and three movements to be performed in a seated position; and two movements in the standing position. The intervention will be delivered by a research coach.<br>|
| No Intervention: Usual Care<br>Usual care provided by neuropsychologist. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Program Feasibility | • Program feasibility measured by program adherence (e.g., self-reported program activities in the past 24 hours, yes/no). | 3 months | 
| Program Acceptability | • Program acceptability measured by patient's perception of the program difficulty. (Too hard, a little too hard, just right, a little too easy, much easy) | 3 months | 
| Feasibility of NIH Toolbox Cognition Battery | Feasibility of NIH Toolbox Cognition Battery measured by administration time. | 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| NIH Toolbox Cognition Battery scores | NIH Toolbox Cognition Battery Fluid Cognition scores (range 59 - 140, higher score means better cognition) | 3 months |