Effect of Noise Blocking During General Anesthesia on Postoperative Pain

Study Overview
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Brief Summary
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To investigate the effect of noise blocking during general anesthesia on postoperative pain in patients undergoing laparoscopic abdominal surgery. The aim of this study was to determine whether noise blocking can reduce postoperative pain, analgesic use, and its possible effects on intraoperative electrocorticogram.

Official Title
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Effect of Noise Blocking During General Anesthesia on Postoperative Pain in Patients Undergoing Laparoscopic Abdominal Surgery

Conditions
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Postoperative Pain

Intervention / Treatment
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* Device: Wear noise-cancelling earphones


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: ASA Classification ⅰ-ⅲ Patients undergoing elective laparoscopic abdominal surgery under general anesthesia Voluntarily accept PCIA and signed informed consent Exclusion Criteria: Patients with previous severe disease Patients with hearing abnormalities Patients requiring mechanical ventilation or undergoing epidural catheters or other types of regional anesthesia after surgery Patients with chronic preoperative pain and/or long-term analgesic use Patients who could not cooperate with the study for any reason

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Patients were randomly divided into intervention group（noise blocking） and control group（No noise blocking）
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: group 1<br>Intraoperative intervention with noise-canceling earphones was performed to isolate the noise | Device: Wear noise-cancelling earphones<br>* Intervention of wearing noise-canceling earphones after general anesthesia<br>|
| No Intervention: group 2<br>After general anesthesia, the intervention of wearing noise-canceling earphones was not given | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Maximum pain score (NRS score) at 0-24 hours postoperatively | NRS score: Pain was assessed on a scale of 0-10, with 0 being no pain and 10 being most painful | From ending of the surgery to 24 hours postoperatively | 
| Pain score (NRS score) at 0-6 hours postoperatively | NRS score: Pain was assessed on a scale of 0-10, with 0 being no pain and 10 being most painful | From ending of the surgery to 6 hours postoperatively | 
| Pain score (NRS score) at 6-12 hours postoperatively | NRS score: Pain was assessed on a scale of 0-10, with 0 being no pain and 10 being most painful | From 6 hours postoperatively to 12 hours postoperatively | 
| Pain score (NRS score) at 12-24 hours postoperatively | NRS score: Pain was assessed on a scale of 0-10, with 0 being no pain and 10 being most painful | From 12 hours postoperatively to 24 hours postoperatively | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Patient controlled analgesia pump analgesic consumption | Analgesic requirements was assessed by recording the volume of patient controlled analgesia pump | From the time when the surgery was completed until to 24 hours after surgery | 
| Postoperative hyperalgesia after surgery | Postoperative hyperalgesia was measured by the ratio of pressure pain threshold at time when discharged from postanesthesia care unit compare to before surgery | from the 30 minutes before the surgery until to 30 minutes after surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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noise blocking, Postoperative Pain