Continuous Quantified EEG in NeuroIntensive Care

Study Overview
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Brief Summary
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To evaluate the ability of NICU staff to interpret, before and after a training period, symmetry, sedation level, seizures activities and artefact on continuous cEEG/qEEG tracings.

Detailed Description
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Using a web based tool, the clinicians of the two study centers will review 24 hours of recording (raw EEG data + derived qEEG variables). The intensivists will evaluate: symmetry, sedation level, seizures activities and artefact on continuous cEEG/qEEG tracings. The same tracings will be blindly reviewed by a certified neurophysiologist (using the app). The neurophysiologist evaluation will be considered as reference. The results of the evaluation will be compared (intensivists vs. neurophysiologist) in order to understand if the intensivists are able to adequately identify the pathological findings. The study period will be: before a formal training after a formal training by neurophysiologist in order to understand if the training is able to improve the intensivists performance.

Official Title
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Utility of Continuous Electroencephalogram and Derived Variables in NeuroIntensive Care

Conditions
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Coma, Traumatic Brain Injury, Subarachnoid Hemorrhage, Ischemic Stroke

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Intensivists wil evaluate daily qEEG recordings of: Patients in coma after a traumatic/vascular event Admitted to neurointensive care and Recorded with continuous EEG for clinical reasons Exclusion Criteria: No EEG recording > 24 hours

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 100 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| qEEG patients<br>All the patients with continuous EEG (>24 hours) in teh two study units | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluate the intensivist's performance in reading qEEG | % of the correct evaluation of qEEG tracings by intensivists vs. neurophysiologist analyzing these domains: symmetry, sedation level, seizures activities and artefact on continuous cEEG/qEEG tracings. The result will be expressed as % of correct answer for each evaluated domain. | 2 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Improvement after the training | Comparison of the correct answers of the intensivist before and after a period of training. The domains evaluated on qEEG are: symmetry, sedation level, seizures activities and artefact on continuous cEEG/qEEG tracings. The result will be expressed as difference in % before and after the training | 12 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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continuous EEG