Database for Predicting Clinical Outcomes of Critically Ill Patients

Study Overview
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Brief Summary
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Australian and New Zealand Intensive Care Society (ANZICS) has built a Center of Outcome and Resource Evaluation (CORE) adult patients database (APD) of adult critically ill patients. ANZICS CORE APD has built an international collaboration of ICU database. National Taiwan University Hospital has joined this international collaboration and built the data according to the APD data dictionary with same value domain attributes and data element attributes. We retrospectively collected the data of patients discharged from the March 1, 2019 to June 30, 2022. Data of this database are permitted to study clinical problems and predict the clinical outcomes of these critically ill patients using statistical methods and machine learning techniques.

Detailed Description
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Data of this database are permitted to study the following clinical issues: including delirium, sepsis, acute kidney injury, acute respiratory distress syndrome, disseminated intravascular coagulation, multiple organ injuries, nutrition, survival status, number of days on ventilators, need for renal replacement therapy, length of stays in intensive care unit, length of stay in hospital, and other relevant clinical outcomes. It is also planned to analyze the clinical prognosis of special disease subgroups and establish a prediction model according to the type of patient's disease.

Official Title
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Predicting Clinical Outcomes of Critically Ill Patients in Intensive Care Units With De-identification Database

Conditions
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Critical Illness

Intervention / Treatment
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* Other: Critical Care


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Critically ill patients admitted to intensive care units Exclusion Criteria: patients aged less than 18 years

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Critically ill patients<br> | Other: Critical Care<br>* Critical care in the intensive care units<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 30-day mortality | mortality status at 30 days after admission to intensive care unit | 30 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Length of stay in intensive care unit | number of days in intensive care unite | Time of discharge from intensive care unit, a median of 2-7 days | 
| Delirium | Events of delirium within 48 hours after ICU admission | 48 hours | 
| Acute kidney Injury | Events of acute kidney injury within 48 hours Time Frame: | 48 hours | 
| Length of stay in intensive care unit | Number of days in intensive care unite | Time of discharge from hospital, more than 1 day | 
| Disseminated intravascular coagulation | Events of disseminated intravascular coagulation within 48 hours after ICU admission | 48 hours | 
| Acute respiratory distress syndrome | Events of acute respiratory distress syndrome within 48 hours after ICU admission | 48 hours |