The Correlation of Preoperative Measurement Parameter on the Predicting of Visual Outcomes Among Patients With Idiopathic Macular Holes

Study Overview
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Brief Summary
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This study retrospectively analyzed the relationship between the preoperative optical coherence tomography(OCT) and optical coherence tomography angiography(OCTA) software related parameters of patients with idiopathic macular hole, the patient's own clinical data and the best corrected visual acuity (BCVA) for at least one month after surgery.

Detailed Description
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After Pars plana vitrectomy combined with removal of the internal limiting membrane (ILM) and air filling, it can not only promote the closure of the macular hole in patients with idiopathic macular hole, but also improve the visual acuity of the affected eye. There are various studies to predict the visual acuity of patients after surgery recovery, but due to many factors that affect the effect of macular hole surgery, the improvement of visual acuity after retinal surgery varies greatly in different eyes. As a new type of ophthalmology device, OCTA plays an important role in measuring the size of the hole and the changes of retinal capillaries. Therefore, this study intends to calculate patient parameters based on OCT and OCTA equipment. Statistical software was used to analyze the relationship between each parameter and the best corrected visual acuity (BCVA) for at least one month after surgery.

Official Title
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Prospective, Observational,Non-interventional Research of The Correlation of Preoperative Measurement Parameter on the Predicting of Visual Outcomes Among Patients With Idiopathic Macular Holes

Conditions
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Macular Holes

Intervention / Treatment
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* Other: No intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: idiopathic MHs, the MH is closed ,and follow-up for at least 1 month after vitrectomy. Exclusion Criteria: High myopia (≥6 diopters,AL≥26.5mm), increased intraocular pressure (IOP, >21 mm Hg) or glaucoma, severe cataract, severe corneal disease，severe systemic conditions that prevent surgery, and history of ocular trauma, intraocular inflammation, retinal vascular disease, or previous ocular surgery

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: No intervention|No intervention|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Macular hole status | macular hole status (open, flat open or closed) | at 1 month after surgery | 
| MLD of macular hole | Calculation of minimum liner diameter of macular hole with optical coherence tomography angiography | Before surgery | 
| BD of macular hole | Calculation of base diameter of macular hole with optical coherence tomography angiography | Before surgery | 
| Choroidal hypertransmission width of macular hole | Calculation of Choroidal hypertransmission width of macular hole with optical coherence tomography angiography | Before surgery | 
| Horizontal ellipsoid band missing diameter of macular hole | Calculation of Horizontal ellipsoid band missing diameter of macular hole with optical coherence tomography angiography | Before surgery | 
| Baseline best-corrected visual acuity | best-corrected visual acuity were gauged with EDTRS charts,recorded in decimals and was converted to logarithm of the minimum angle of resolution units for statistical analysis | Before surgery | 
| best-corrected visual acuity at 1 month | best-corrected visual acuity were gauged with EDTRS charts,recorded in decimals and was converted to logarithm of the minimum angle of resolution units for statistical analysis | at 1 month after surgery | 
| best-corrected visual acuity at 2 months | best-corrected visual acuity were gauged with EDTRS charts,recorded in decimals and was converted to logarithm of the minimum angle of resolution units for statistical analysis | at 2 months after surgery | 
| best-corrected visual acuity at 3 months | best-corrected visual acuity were gauged with EDTRS charts,recorded in decimals and was converted to logarithm of the minimum angle of resolution units for statistical analysis | at 3 months after surgery | 
| best-corrected visual acuity at 4 months | best-corrected visual acuity were gauged with EDTRS charts,recorded in decimals and was converted to logarithm of the minimum angle of resolution units for statistical analysis | at 4 months after surgery | 
| best-corrected visual acuity at 5 months | best-corrected visual acuity were gauged with EDTRS charts,recorded in decimals and was converted to logarithm of the minimum angle of resolution units for statistical analysis | at 5 months after surgery | 
| best-corrected visual acuity at 6 months | best-corrected visual acuity were gauged with EDTRS charts,recorded in decimals and was converted to logarithm of the minimum angle of resolution units for statistical analysis | at 6 months after surgery | 
| FAZ area of macular hole | Calculation of foveal avascular zone (FAZ) area of macular hole with optical coherence tomography angiography | Before surgery | 
| FAZ area of macular hole at 1 month | Calculation of foveal avascular zone (FAZ) area of macular hole with optical coherence tomography angiography | at 1 month after surgery | 
| FAZ area of macular hole at 2 months | Calculation of foveal avascular zone (FAZ) area of macular hole with optical coherence tomography angiography | at 2 months after surgery | 
| FAZ area of macular hole at 3 months | Calculation of foveal avascular zone (FAZ) area of macular hole with optical coherence tomography angiography | at 3 months after surgery | 
| FAZ area of macular hole at 4 months | Calculation of foveal avascular zone (FAZ) area of macular hole with optical coherence tomography angiography | at 4 months after surgery | 
| FAZ area of macular hole at 5 months | Calculation of foveal avascular zone (FAZ) area of macular hole with optical coherence tomography angiography | at 5 months after surgery | 
| FAZ area of macular hole at 6 months | Calculation of foveal avascular zone (FAZ) area of macular hole with optical coherence tomography angiography | at 6 months after surgery | 
| CRT of macular hole | Calculation of central retinal thickness(CRT) of macular hole with optical coherence tomography angiography | Before surgery | 
| CRT of macular hole at 1 month | Calculation of central retinal thickness(CRT) of macular hole with optical coherence tomography angiography | at 1 month after surgery | 
| CRT of macular hole at 2 months | Calculation of central retinal thickness(CRT) of macular hole with optical coherence tomography angiography | at 2 months after surgery | 
| CRT of macular hole at 3 months | Calculation of central retinal thickness(CRT) of macular hole with optical coherence tomography angiography | at 3 months after surgery | 
| CRT of macular hole at 4 months | Calculation of central retinal thickness(CRT) of macular hole with optical coherence tomography angiography | at 4 months after surgery | 
| CRT of macular hole at 5 months | Calculation of central retinal thickness(CRT) of macular hole with optical coherence tomography angiography | at 5 months after surgery | 
| CRT of macular hole at 6 months | Calculation of central retinal thickness(CRT) of macular hole with optical coherence tomography angiography | at 6 months after surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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idiopathic full thickness macular hole, OCTA, postoperative best corrected visual acuity, vitrectomy