Sensorimotor Training Versus Resistance Training in Patients With Knee Osteoarthritis

Study Overview
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Brief Summary
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People with knee osteoarthritis (OA) have functional instability and defective neuromuscular function, it was recently suggested that sensorimotor exercises may be important and needed to improve the effectiveness of training programs for these patients. This study objective was to compare the effectiveness of a supervised resistance muscular training (RT) versus sensorimotor training (SMT) for patients with Knee OA, on decrease of pain and functional improvement.

Official Title
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Efficacy of a Sensorimotor Training in Patients With Knee Osteoarthritis: a Randomized Clinical Trial

Conditions
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Knee Osteoarthritis

Intervention / Treatment
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* Other: Sensorimotor training (SMT)
* Other: Resistance training (RT)
* Other: Control group (CG)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients diagnosed with tibiofemoral osteoarthritis; Both genders; Age> 50 years <75 years; Completion of clinical and radiological criteria of the American College of Rheumatology (ACR) criteria for knee OA; No physical activity in the previous 3 months; Education level from the 4th grade of primary school. Exclusion Criteria: uncontrolled hypertension; decompensated diabetes mellitus; uncontrolled thyroid diseases; cardiorespiratory disease (ischemia, arrhythmia, chest pain, or exercise-induced bronchospasm), liver abnormalities; Patients with grade IV functional limitation that needed devices to walk(Kellgren-Lawrence radiographic classification); Patients in a period of sick leave by the INSS or any other related factor; Other rheumatic diseases.

Ages Eligible for Study
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Minimum Age: 50 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: sensorimotor training (SMT)<br> | Other: Sensorimotor training (SMT)<br>* The group realized 16 weeks of sensorimotor training, twice a week, with duration of 30 minutes each session. The intervention included agility and coordination exercises, perturbation training and stretching exercises. Also, the participants received orientation about the knee osteoarthritis.<br>* Other names: Agility/perturbation training; proprioceptive training; neuromuscular training;|
| Active Comparator: Resistance training (RT)<br> | Other: Resistance training (RT)<br>* The group realized 16 weeks of resistance training for the quadriceps and hamstring muscles, twice a week, with duration of 30 minutes each session. The intervention included strength leg raises, simple quadriceps and hamstring strengthening with cuff weights realized in 3 sets of ten repetition maximum(10RM) for each muscle group. The group also realized stretching exercises for lower limbs and received orientation about the knee osteoarthritis.<br>|
| Sham Comparator: Control group (CG)<br> | Other: Control group (CG)<br>* Patients in this group also received information about knee osteoarthritis and realized the same warm-up and cool-down intervention realized in the interventional groups. During 16 weeks they went to the ambulatory twice a week to perform 5 minutes of stationary bicycle and 5 minutes of stretching exercises for lower limbs.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual analogue scale of pain (VAS) |  | 16 weeks | 
| Get Up and Go Test |  | 16 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) |  | 16 weeks | 
| electromyographic analysis of quadriceps muscle (EMG) |  | 16 weeks | 
| isometric quadriceps strength |  | 16 weeks | 
| Medical Outcomes Study Short Form (SF-36) | Generic, patient-report measure designed to assess health-related quality of life, comprises 36 items divided into 8 subscales. Physical Functioning Role Limitations due to Physical Problems General Health Perceptions Vitality Social Functioning Role Limitations due to Emotional Problems General Mental Health Health Transition | 16 weeks | 
| Berg Balance Test |  | 16 weeks | 
| Tinetti Test |  | 16 weeks | 
| activities of daily living scale (ADLS) |  | 16 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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knee osteoarthritis, exercise therapy, resistance training, proprioception