linjc16/ctgov huggingface dataset:
Neural Development of Deductive Reasoning

Study Overview
=================
Brief Summary
-----------------
Children's understanding of linear-order (e.g., Dan is taller than Lisa, Lisa is taller than Jess) and set-inclusion (i.e., All tulips are flowers, All flowers are plants) relationships is critical for the acquisition of deductive reasoning, that is, the ability to reach logically valid conclusions from given premises. Behavioral and neuroimaging studies in adults suggest processing differences between these relations: While arguments that involve linear-orders may be preferentially associated with spatial processing, arguments that involve set-inclusions may be preferentially associated with verbal processing. In this study, we use functional magnetic resonance imaging to investigate how and when these processing differences appear in children from 8 to 14.

Official Title
-----------------
Neural Development of Deductive Reasoning: an fMRI Study of Relational and Categorical Reasoning in Children

Conditions
-----------------
Healthy Volunteers

Intervention / Treatment
-----------------
* Other: fMRI scanning


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Right-handed Affiliated to the French social security Whose parents gave informed consent Exclusion Criteria: Neurological disorders Psychiatric disorders Birth complications requiring admission into neonatal intensive care unit Medication affecting central nervous system processing Significant hearing impairment Uncorrected visual impairment Non-native English speaker Contraindications for MRI

Ages Eligible for Study
-----------------
Minimum Age: 8 Years
Maximum Age: 14 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Basic Science
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Brain activity during reasoning<br> | Other: fMRI scanning<br>* All participants are scanned while evaluating linear-order and set-inclusion reasoning problems<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Identification of brain regions engaged in linear-order and set-inclusion reasoning | Brain activity measured using fMRI | 30 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Degree of overlap between brain regions involved in linear-order and set-inclusion reasoning | Degree of overlap in brain activity measured using fMRI | 30 days | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
fMRI, reasoning, development
Early Feasibility Study to Assess Safety and Device Performance of AcoustiCare™

Study Overview
=================
Brief Summary
-----------------
AcoustiCareTM is a non-invasive clinical tool used for the detection of intracardiac pressures using heart sounds in patients with heart failure.

Official Title
-----------------
Early Feasibility Study to Assess Safety and Device Performance of AcoustiCare™

Conditions
-----------------
Heart Failure，Congestive

Intervention / Treatment
-----------------
* Device: AcoustiCare


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Male or female subjects between the ages of 18 - 80 years Willing and able to sign informed consent form Normal subjects without a history of heart disease who are recruited from the surrounding community Subjects with heart failure undergoing treatment in a hospital setting Exclusion Criteria: Hemodynamic instability (Systolic BP>180 or <90 and Diastolic BP>90 and <60) Acute coronary syndrome Prior heart transplant recipients Subjects who are pacemaker dependent Severe obesity (body mass index > 40 kg/m2) Subjects who are pregnant

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Other
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: AcoustiCare<br>Single Arm | Device: AcoustiCare<br>* Electronic stethoscope<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of Adverse Events | The safety of the Acousticare device will be assessed by reviewing adverse events in all patients enrolled in the study | Subjects will be assessed for adverse events through study completion, an average of 1 day |
Association Between Vitamin D Deficiency and Preeclampsia: A Case Control Study

Study Overview
=================
Brief Summary
-----------------
To find out if lower levels of vitamin D is more prevalent in preeclamptic women

Conditions
-----------------
Pre-Eclampsia

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Parity: primigravida. Age: 18 - 35 years. Singleton pregnancy. Gestational age: 36-40 weeks. No past history of any medical disorder and with no other medical complications during pregnancy Exclusion Criteria: Women with preexisting medical conditions like rheumatoid arthritis, thyroid, hepatic or renal failure, metabolic bone disease, diabetes mellitus, malabsorption and lupus. History of intake of medications influencing bone, vitamin D or calcium metabolism e.g. antiepileptic, theophylline, antitubercular drugs in the last 6 months. Women with multiple pregnancy. Women with congenital fetal malformation. Women with known thrombophilia

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 35 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| preeclamptic group<br>Blood pressure: greater than or equal to 140 mmHg systolic or greater than or equal to 90 mmHg diastolic on two occasions at least 4 hours apart after 20 weeks of gestation (Roberts et al., 2013). Proteinuria: protein/creatinine ratio greater than or equal to 0.3 In the absence of proteinuria, a new-onset hypertension with new onset of the following: thrombocytopenia: platelet count less than 100.000/microliter renal insufficiency: serum creatinine greater than 1.1 mg/dl impaired liver function: elevated concentration of liver transaminases pulmonary edema cerebral or visual symptoms Severe right upper quadrant or epigastric pain unresponsive to medication. | |
| non preeclamptic group<br>All are normotensive with blood pressure <140/90 with no proteinuria. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| vitamin D level in preeclamptic and non preeclamptic women |  | six months |
Study of Improving Gait Parameters When Using a Cane in Light Touch Condition in Elderly People With and Without Walking Difficulties

Study Overview
=================
Brief Summary
-----------------
This project aims to study the effect of haptic sensory information delivered at the hand using a cane in light touch or light support condition on postural stability and spatial and temporal gait parameters of elderly subjects with and without walking difficulties

Conditions
-----------------
Disorders of Balance

Intervention / Treatment
-----------------
* Other: postural task
* Other: walk task


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: presence of gait disturbance or balance disorders defined by a geriatric assessment and / or a walking speed test Exclusion Criteria: presence of acute problems or central or peripheral neurological severe sequelae occurrence of a recent fracture of the lower limbs or spinal fracture cognitive disorders presence of comorbidities: blindness, heart or severe respiratory failure, disabling osteoarthritis of the hands or legs, severe malnutrition, muscle atrophy, untreated orthostatic hypotension patients using a cane to a mechanical support

Ages Eligible for Study
-----------------
Minimum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Supportive Care
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: elderly people with walking difficulties<br>subjects with proven gait disturbance and balance will be recruited from a walking speed test and a standardized geriatric assessment by a geriatrician | Other: postural task<br> <br> Other: walk task<br> <br> |
| Active Comparator: elderly people without walking difficulties<br>subjects with no gait disturbance and balance disorders will be recruited from a walking speed test and a standardized geriatric assessment, once the subjects with gait disturbance and balance disorders have been recruited in order to make a match on the age criterion | Other: postural task<br> <br> Other: walk task<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| number of use of the cane |  | 12 mois |
Mechanically Optimizing Cardiac Preload in Heart Failure Patients

Study Overview
=================
Brief Summary
-----------------
The purpose of the current study is to determine if partial balloon occlusion of the inferior vena cava can optimize cardiac pre-load and subsequently pulmonary pressures and cardiac output as a novel method to unload pulmonary edema and other symptoms of decompensated congestive heart failure. All products in this study are FDA approved and adhere to the specifications of the intended use.

Official Title
-----------------
Mechanically Optimizing Cardiac Preload Using Partial Inferior Vena Cava Occlusion to Reduce Pulmonary Pressures in Heart Failure Patients in Heart Failure Patients

Conditions
-----------------
Heart Failure

Intervention / Treatment
-----------------
* Diagnostic Test: Partial IVC occlusion


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Subjects scheduled to undergo a right heart catheterization at Saint Thomas Hospital. New York Heart Association (NYHA) II or III. Subjects must be last least 18 years of age. A left ventricular ejection fraction >= 20%. Pulmonary artery occlusion pressure, or pulmonary wedge pressure >20 mmHg. Exclusion Criteria: Subjects without sinus rhythm. Evidence of right heart failure. Patients with primary pulmonary hypertension Pulmonary wedge pressure <15mmHg. Significant lung disease, such as prior diagnosis of COPD. Resting or dynamic outflow tract gradient Patients with left bundle branch block

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| HF patients<br>Decompensated heart failure patients undergoing right heart catheterization. | Diagnostic Test: Partial IVC occlusion<br>* Partial balloon occlusion of the inferior vena cava.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in pulmonary arterial pressures | Change in the measured mean pulmonary arterial pressure | During partial balloon occlusion | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in cardiac output | Change in cardiac output measured in liters per minute | During partial balloon occlusion | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
pulmonary edema, preload
Allergy and Ashthma in Children Who Were Fed Supplemented Infant Formula

Study Overview
=================
Brief Summary
-----------------
Allergy and Asthma study of children (3 - 7 Years of age) who participated in randomized trials of supplemented infant formula during infancy conducted by The Retina Foundation of the Southwest .

Official Title
-----------------
Allergy and Asthma in Children Who Were Fed Supplemented Infant Formula (3-7 Years of Age)

Conditions
-----------------
Allergy and Asthma

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Children who participated in randomized trials of supplemented infant formula conducted by The Retina Foundation of the Southwest during infancy Exclusion Criteria: -

Ages Eligible for Study
-----------------
Minimum Age: 3 Years
Maximum Age: 7 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prevalence of asthma and allergy related diagnosis in medical records for ages 3 - 7 years |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prevalence of Serious Adverse Events in medical records |  |  | 
| Long-term growth |  |  |
Effects of Physical Activity on Quality of Life Among Female Undergraduate Students

Study Overview
=================
Brief Summary
-----------------
The main objective of the study is to determine the effects of physical activity on quality of life among female undergraduate students

Official Title
-----------------
Effects of Physical Activity on Quality of Life Among Female Undergraduate Students

Conditions
-----------------
Quality of Life

Intervention / Treatment
-----------------
* Behavioral: Light Physical Activity
* Behavioral: Moderate Physical Activity
* Behavioral: Vigourous Physical Activity


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: -moderate level of academic stress measured on academic stress scale Exclusion Criteria: students with diagnosed psychological disorders systematic diseases

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 25 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Light Physical Activity (LPA)<br>The guidelines from Rapid Assessment of Physical Activity (RAPA) participants were asked to perform Leisure Walk for 35 minutes | Behavioral: Light Physical Activity<br>* The guidelines from Rapid Assessment of Physical Activity (RAPA) participants were asked to perform Leisure Walk for 35 minutes<br>|
| Active Comparator: Moderate Physical Activity (MPA)<br>The guidelines from Rapid Assessment of Physical Activity (RAPA) participants were asked to perform Brisk Walk for 30 minutes | Behavioral: Moderate Physical Activity<br>* The guidelines from Rapid Assessment of Physical Activity (RAPA) participants were asked to perform Brisk Walk for 30 minutes<br>|
| Active Comparator: Vigorous Physical activity (VPA)<br>The guidelines from Rapid Assessment of Physical Activity (RAPA) participants were asked to perform jogging for 15 minutes | Behavioral: Vigourous Physical Activity<br>* The guidelines from Rapid Assessment of Physical Activity (RAPA) participants were asked to perform jogging for 15 minutes<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Quality of Life (QOL), | The short form (SF-36) was used to observe Quality of Life (QOL), Minimum score is 0 and maximum is 100. maximum score indicate high quality of life. | A change from baseline to six weeks of intervention will be observed |
Photorefractive Keratectomy and Corneal Cross-linking in Keratoconus

Study Overview
=================
Brief Summary
-----------------
Evaluation of the safety and efficacy of surface ablation followed by Collagen Cross-linking in patients with keratoconus

Conditions
-----------------
Keratoconus

Intervention / Treatment
-----------------
* Procedure: Simultaneous Photorefractive Keratectomy and Collagen Cross-linking in patients with keratoconus


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: contact lens intolerance corneal thickness > 450 micrometers Keratometry < 56 diopters Astigmatism < 6 diopters Exclusion Criteria: corneal thickness < 450 micrometers Keratometry > 56 diopters Astigmatism > 6 diopters

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Refractive surgery<br>Patients with keratoconus treated with simultaneous photorefractive keratectomy and Corneal collagen cross-linking. | Procedure: Simultaneous Photorefractive Keratectomy and Collagen Cross-linking in patients with keratoconus<br>* Photorefractive Keratectomy followed by Collagen Cross-linking in patients with keratoconus in the same surgical setting<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The change of visual acuity following Photorefractive Keratectomy and Corneal Collagen Cross-linking in patients with Keratoconus | The change of visual acuity from baseline in patients suffering from keratoconus following treatment with Photorefractive Keratectomy and Corneal Collagen Cross-linking. | 6 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Keratoconus, Ectasia, Corneal Cross-linking
Outcome of Longterm Antithrombotic Therapy in Acute Coronary Syndrome Patients

Study Overview
=================
Brief Summary
-----------------
This observational study will based on the Register of Information and Knowledge About Swedish Heart Intensive Care Admissions (RIKS-HIA) and the Swedish Coronary Angiography and Angioplasty Registry (SCAAR) which since 2009 are merged into The Swedish Web-system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies (SWEDEHEART). The aim of this study is to investigate the impact of different antithrombotic treatment options (treatment duration, type of treatment and combination of treatments) in Acute Coronary Syndrome (ACS) patients on outcomes such as recurrent ischemic events and mortality.

Official Title
-----------------
A Retrospective Epidemiological Study to Investigate Outcome and Mortality With Longterm Antithrombotic Therapy in Acute Coronary Syndrome Patients

Conditions
-----------------
Acute Coronary Syndrome, Myocardial Infarction

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patient with an event of ACS under the study period Patient found in the National Registry of Drug Prescriptions and treated or not treated with antithrombotic drug/s (acetylsalicylic acid and/or either clopidogrel/ticlopidine/prasugrel and/or warfarin) Exclusion Criteria: Patients will not be excluded from the database if they fulfill inclusion criteria.
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| dual antiplatelet treatment 12 months after ACS event<br> | |
| dual antiplatelet treatment 6 months after ACS event<br> | |
| dual antiplatelet treatment 3 months after ACS event<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| number of patients with adverse events in patient groups with different antithrombotic treatment strategies | adverse events such as: mortality, re-infarction, revascularization, ischemic- and non-ischemic stroke and bleeding | up to 5 years and 6 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
clopidogrel, aspirin, percutaneous coronary intervention, coronary stenting, antiplatelet