At Home Brain Stimulation Studies of Memory and Memory Awareness

Study Overview
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Brief Summary
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The main goal of this research is to determine the role of several brain regions in memory processes and cognitive functions. Participants will be remotely supervised via video chat while self-administering tDCS, a form of non-invasive brain stimulation. Before participating in the experiment, participants will be properly trained on use of the remote tDCS device and screened for eligibility. While using the tDCS device, participants will be engaging in tasks that assess different aspects of memory and executive functioning. By using remotely supervised tDCS while participants are completing these cognitive tasks, we will be able to make causal claims about the role of the targeted brain regions in different cognitive processes.

Official Title
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At Home Brain Stimulation Studies of Memory and Memory Awareness

Conditions
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Healthy

Intervention / Treatment
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* Device: remotely supervised transcranial direct current stimulation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: between the ages of 18-35 normal or corrected to normal vision fluent in English and speaking English since age 5 right handed Exclusion Criteria: chronic skin disease or medical skin condition unhealed wound or open skin on the scalp, face, neck, or forehead metal or electrode implants (e.g., cochlear implants, pacemakers, metal plates, rods, or screws in their head; for complete detail, see the screening form) seizures or a family history of seizures, or are taking medications with a lowered seizure threshold pregnant or lactating any neurologic or psychiatric diseases certain hair styles (dreadlocks, cornrows, etc) or hair coverings (e.g., wigs, hajibs, etc that will not be removed; note that a request can be made for an experimenter of a specific gender)

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 35 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: DLPFC stimulation<br>F3-SO montage or OLE optimized with 2 mA stimulation for up to 30 min during memory and metamemory task. | Device: remotely supervised transcranial direct current stimulation<br>* Low levels of electrical current are applied across the scalp to induce small changes in brain activity. This is done using remote supervision.<br>|
| Sham Comparator: Sham tDCS<br>F3-SO montage or OLE optimized with sham stimulation for up to 30 min during memory and metamemory task. | Device: remotely supervised transcranial direct current stimulation<br>* Low levels of electrical current are applied across the scalp to induce small changes in brain activity. This is done using remote supervision.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Memory performance | % Correct on the Memory Task | through study completion, an average of 4 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Memory Confidence | Average % Confidence on the Memory Task | through study completion, an average of 4 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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transcranial direct current stimulation, memory, metacognition, brain