Self Medication With Oral Morphine After Total Knee Arthroplasty.

Study Overview
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Brief Summary
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The study aims to compare two post operative pain management strategy's, traditional nurse dispensed pain control versus patient self medication. The investigators aim to establish if patients who self medicate have differing pain levels than those who take nurse dispensed oral morphine.

Official Title
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Self Medication With Oral Morphine After Total Knee Arthroplasty. A Randomised Controlled Trial Comparing Self Medication With Standard Nurse Dispensing. Is There a Difference in Morphine Consumption, Pain, Patient Satisfaction or Safety?

Conditions
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Arthroplasty, Knee Replacement, Pain Control

Intervention / Treatment
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* Behavioral: Nurse dispensed oral morphine.
* Behavioral: Patient self medication of oral morphine.


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients requiring total knee replacement surgery willing to provide written, informed consent. Exclusion Criteria: Unable to safely self medicate. Allergy to morphine. Unable to provide consent. Contraindication to the standardised anaesthetic or standard postoperative care. Not consenting to an element of the standardised anaesthetic. Pre-operative use of strong opiates e.g. Oramorph, MST, Oxynorm.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Nurse dispensed oral morphine solution.<br> | Behavioral: Nurse dispensed oral morphine.<br>* Nurse will dispense oral morphine on request from the patient.<br>|
| Active Comparator: Self medicated oral morphine solution.<br> | Behavioral: Patient self medication of oral morphine.<br>* Patients will self medicate their oral morphine pain control solution following surgery.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To establish if patients who self medicate with oral morphine have differing pain levels than those who take nurse dispensed oral morphine. |  | one year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To identify if patients who self medicate with oral morphine take a significantly different amount of morphine compared with those who take nurse dispensed oral morphine. |  | one year | 
| To compare whether patients who self medicate with oral morphine have a significantly altered level of side effects compared with those who take nurse dispensed oral morphine. |  | one year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Knee replacement, Pain control, Self medication