The Observation About the Effects of Internal Carotid Artery Stenosis on Fundus Vessels and the Changes of Fundus Vessels After Interventional Therapy

Study Overview
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Brief Summary
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The investigators plan to collect 30 participants with internal carotid artery stenosis to observed the relationship between the degree of internal carotid artery stenosis and fundus vessels （and blood flow）density before operation, and compared with participants without internal carotid artery stenosis.The fundus blood flow density will be observed after intervention operation in order to see whether the operation is effective to improve the density of fundus vessels and blood flow or not.

Official Title
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The Observation About the Effects of Internal Carotid Artery Stenosis on Fundus Vessels and the Changes of Fundus Vessels After Interventional Therapy

Conditions
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Internal Carotid Artery Stenosis

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients who have been diagnosed with carotid artery stenosis and need surgery; Patients whose vision won't get worse soon; Patients have not had any eye surgeries; Patients with complete profile. Exclusion Criteria: Patients with severe systemic disease; Patients with poor dioptric stroma; Patients with nystagmus; Patients with incomplete profile.

Ages Eligible for Study
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Minimum Age: 45 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The differences of perfusion density in the Forum of the optical coherence tomography angiography（OCTA ）of Zeiss Company | The perfusion density differences between the fundus vessels（both the macula area and the optic disc area） on the carotid artery stenosis side and the not-significant narrowing side，or the perfusion density differences between the fundus vessels（both the macula area and the optic disc area） on the carotid artery stenosis side and the side with carotid artery stenosis of different degrees. | 2022-01-31 | 
| The differences of perfusion density in the Forum of the optical coherence tomography angiography（OCTA ）of Zeiss Company | The perfusion density differences between the fundus vessels on the carotid artery stenosis side and the same side after interventional surgery. | 2022-02-14 | 
| The differences of vessel density in the Forum of the optical coherence tomography angiography（OCTA ）of Zeiss Company | The vessel density differences between the fundus vessels（both the macula area and the optic disc area） on the carotid artery stenosis side and the not-significant narrowing side，or the vessel density differences between the fundus vessels（both the macula area and the optic disc area） on the carotid artery stenosis side and the side with carotid artery stenosis of different degrees. | 2022-01-31 | 
| The differences of vessel density in the Forum of the optical coherence tomography angiography（OCTA ）of Zeiss Company | The vessel density differences between the fundus vessels on the carotid artery stenosis side and the same side after interventional surgery. | 2022-02-14 | 
| The perimeter and area of the fovea avascular zone（FAZ）in the Forum of the optical coherence tomography angiography（OCTA ）of Zeiss Company | The differences between the perimeter and area of the fovea avascular zone（FAZ） of the carotid artery stenosis side before and after interventional surgery. | 2022-02-14 |