Strategy for Daily Activity Improvement in Patients With Parkinson's Disease

Study Overview
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Brief Summary
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The symptoms and signs of patients with Parkinson's disease (PD) include bradykinesia, rigidity, tremor and poor sensory integration, which result in mobility disability. Present integrated research project tries to investigate the effects of different physical therapy interventions on daily activities in patients with PD. This integrated research project includes 3 subprojects as follows. The title of Subproject 1 is Three dimensional motion analysis of daily activities with functional insole in Parkinsonian patients. The title of Subproject 2 is Immediate and long-term effects of novel plantar mechanical device on postural control in standing and gait performance in people with Parkinson's disease. The title of Subproject 3 is Upper extremity hand function and coordination during functional movement in patients with Parkinson's disease. This multidisciplinary research project collaborates with Department of Physical Therapy, and Department of Medicine in Tzu Chi University. Furthermore, this integrated study also works with Department of Neurology, Department of Neurosurgery, as well as Department of Rehabilitation in Tzu Chi Hospital to improve the mobility in patients with PD. This is a three-year integrated project, and the common purposes of this project in each are as follows. In the first year, it is to compare the daily functional difference between the healthy and the Parkinsonian patients. In the second year, it is to examine the immediate and short-term effects of different interventions on daily activities in Parkinsonian patients.The third year is for upper extremity functional assessment.

Detailed Description
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In the first year, it is to compare the functional difference of biomechanics and motor control between the healthy and the Parkinsonian patients. In the second year, it is to examine the immediate and short-term effects of functional foot insole and the kinetic training on daily activities in Parkinsonian patients. In the third year, it is to examine the hand tremor during drawing, and the coordination during reaching in Parkinsonian patients.

Official Title
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Three Dimensional Motion Analysis of Daily Activities With Functional Insole in Parkinsonian Patients

Conditions
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Parkinson Disease

Intervention / Treatment
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* Device: foot insole


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Stage II IV of Hoehn and Yahr Staging of Parkinson's Disease and normal subjects, whose age between 40 75. Exclusion Criteria: Brain injury or hemorrhage, including stroke, etc.

Ages Eligible for Study
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Minimum Age: 40 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: To compare between experimental and control groups.
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Intervention<br>different interventions including foot insole or kinetic training | Device: foot insole<br>* arch support and toe extension<br>* Other names: spiral drawing;|
| No Intervention: control<br>No intervention | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Ambulation | gait cycle | 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Foot pressure | center of pressure | 1 year | 
| Spiral drawing | Figure plot | 1 year | 
| Coordination | Reaching movement | 1 year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Parkinson disease, Quality of life, Physical therapy, tremor, coordination, gait analysis