linjc16/ctgov huggingface dataset:
Hip Protector for Prevention of Hip Fracture

Study Overview
=================
Brief Summary
-----------------
This study aims to evaluate the efficacy of the investigators PSU hip protector for prevention of fracture in elderly.The eligible patients include those with previous diagnosed as unilateral hip fracture. They will be randomized into 2 groups;psu hip protector and no protector. The patients will be instructed to wear the protector fulltime.The inceidence of hip fracture will be compared between both group at the end of 1 year.

Official Title
-----------------
PSU Hip Protector for Prevention of Hip Fracture From Falling

Conditions
-----------------
Hip Fracture

Intervention / Treatment
-----------------
* Device: PSU hip protector


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with previous diagnosed as unilateral hip fracture Exclusion Criteria: Poor communicative ability Cannot independently ambulate Local skin problem at trocahnteric area

Ages Eligible for Study
-----------------
Minimum Age: 50 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: No hip protector<br>no hip protector | Device: PSU hip protector<br>* hip protetor<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| incidence of new hip fracture |  | 6 months, 1 ,2 and 3 yrs | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| SF 36 |  | 6 months, 1 ,2 and 3 yrs | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
hip fracture, back support
Intra-observer and Inter-observer Variability With Dynamic Contour Tonometry.

Study Overview
=================
Brief Summary
-----------------
The aim of the protocol is to document intra-observer and inter-observer variability with dynamic contour tonometry, and will also test the theory that pulse amplitude, as measured by dynamic contour tonometry, is correlated with the difference in systolic and diastolic blood pressures.

Official Title
-----------------
Intra-observer and Inter-observer Variability With Dynamic Contour Tonometry.

Conditions
-----------------
Intraocular Pressure

Intervention / Treatment
-----------------
* Device: Dynamic contour tonometry


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Normal, healthy eyes Minimal to moderate refractive error Willingness to participate in the study Exclusion Criteria: Diagnosis of any type of glaucoma Any prior ocular surgery Any prior ocular trauma Any known anterior segment pathology

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Observation<br>Variability will be assessed between each examiner. | Device: Dynamic contour tonometry<br>* Observe variability of measurements by dynamic contour tonometry<br>* Other names: DCT;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The variability of intraocular pressure measurements using dynamic contour tonometry |  | Same day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Observe how pulse amplitude, as measured by dynamic contour tonometry, correlates with the difference in systolic and diastolic blood pressures |  | Same day | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
dynamic contour tonometry, variability, pulse amplitude, Ocular pulse amplitude
Chemotherapy Efficacy and Follow-up Study of Hepatitis B Virus Infection and Reactivation in Children With Leukemia

Study Overview
=================
Brief Summary
-----------------
Children with clinically diagnosed leukemia may experience occult HBV infection after chemotherapy immunosuppressive therapy, which may affect the normal course of leukemia treatment. However, this is not caused by clinically relevant diagnosis and treatment measures but exists in vivo.

Detailed Description
-----------------
The clinical diagnosis of children with leukemia may be due to the influence of leukemia disease on the immune cells of the children and the damage to the immune system due to immunosuppressive therapy in children. Therefore, the risk of contracting hepatitis B virus is relatively high, and some children are In the treatment of immunosuppressive chemotherapy (later), the reactivation of occult HBV infection has an impact on the normal course of leukemia treatment. However, this is not a clinically relevant diagnosis and treatment measure. It is necessary to avoid unnecessary conflicts between clinical doctors and patients as much as possible.

Official Title
-----------------
Chemotherapy Efficacy and Follow-up Study of Hepatitis B Virus Infection and Reactivation in Children With Leukemia

Conditions
-----------------
Reactivation of Hepatitis B Virus

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: The clinical diagnosis of children with leukemia received systemic chemotherapy. Exclusion Criteria: Children with non-leukemia and children without appropriate treatment.

Ages Eligible for Study
-----------------
Minimum Age: 1 Year
Maximum Age: 16 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| HBV-DNA positive | Positive HBV nucleic acid test | 1-year | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Leukemia, occult hepatitis B virus infection
Ventricular Electrical Synchronization by Stimulating Left and Right Bundle Branches Area in Pacing-indicated Patients

Study Overview
=================
Brief Summary
-----------------
This is a prospective, single-site, non-randomized, acute feasibility clinical study. The purpose of this study is to explore the electrocardiogram (ECG) characteristics of simultaneous stimulation of right and left bundle branches area.

Detailed Description
-----------------
Many pacemaker patients have cardiac conduction system disease and thus need ventricular pacing. Traditional ventricular pacing causes ventricular dyssynchrony that in turn causes cardiac contraction dysfunction. CRT pacing provides better ventricular synchronization, but not the optimal, especially in patients with narrow QRS. CRT non-response rate is at 30%. His bundle pacing utilizes naturel His bundle-Purkinjie system to provide optimal physiological pacing. But many pacing-indicated patients have abnormal His bundle-Purkinje system, thus His bundle pacing cannot provide optimal pacing in patients with abnormal cardiac conduction system. Moreover, the pacing threshold is high during His bundle pacing. More recently, left bundle branch pacing is proposed. However, LBBP will generate right bundle branch block pattern, another kind of weak ventricular synchronization. Thus, the investigators propose to excite the left and right bundle branches area simultaneously to normalize ventricular synchronization. The purpose of this study is to explore the electrocardiogram (ECG) characteristics of simultaneous stimulation of right and left bundle branches area.

Official Title
-----------------
Ventricular Electrical Synchronization by Stimulating Left and Right Bundle Branches Area in Pacing-indicated Patients

Conditions
-----------------
Cardiac Pacing, Pacing Therapy, Pacemaker

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Aged from 18 to 80 years old Subjects who are willing to provide Informed Consent Subjects who have pacing indications or indications for CRT, and will receive pacemaker or CRT therapy Exclusion Criteria: Subjects who have contra-indications for pacing therapy or CRT CRT up-graded subjects Ventricular hypertrophy Subjects who have medical conditions that would limit study participation Subjects who are pregnant or have a plan for pregnancy during the study Subjects who are not willing to provide Informed Consent

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| QRS duration | The primary endpoint is QRS duration during bundle branches area pacing | During implant |
Community-Based Environmental Health Intervention

Study Overview
=================
Brief Summary
-----------------
This community-based project, called the Together for Agricultural Safety project, was developed to help farmworkers reduce their exposure to dangerous agricultural chemicals (such as pesticides) through education and social marketing. The project is a partnership of university researchers and the Farmworkers Association of Florida. After collecting extensive data from farmworkers, health providers and farm owners about primary means of pesticide exposure we are collaboratively developing an intervention that will reduce pesticide exposure by educating workers and owners about: the need to have adequate washing facilities; to wash hands frequently; to obey reentry intervals; to change work clothes after work to prevent child exposure and more.

Official Title
-----------------
Community-Based Environmental Health Intervention

Conditions
-----------------
Poisoning

Intervention / Treatment
-----------------
* Behavioral: Behavior modification through social marketing


Participation Criteria
=================
Eligibility Criteria
-----------------
Must be an agricultural worker in the fernery or nursery industries in Central Florida.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: Behavior modification through social marketing|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Pesticide, Farmworker, Occupational health
Diagnostic Performance of Coronary Calcification Detection on CT Scan

Study Overview
=================
Brief Summary
-----------------
thoracic pain is one of the most frequent reasons for consulting the emergency room. Chest pain can be a sign of different pathologies with a wide range of severity, from life-threatening aortic dissection or myocardial infarction to chest pain during an anxiety attack. Efficient triage of patients is therefore a crucial issue for emergency physicians in order not to ignore an acute coronary event requiring early and specific management. The investigators seek to evaluate whether a diagnostic strategy based on a thoracic CT scan to rule out coronary calcifications and a single troponin assay can exclude an acute coronary event with sufficient accuracy compared to usual management.

Official Title
-----------------
Diagnostic Performance of Coronary Calcification Detection on CT Scan

Conditions
-----------------
Acute Coronary Syndrome

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion criteria: Adult patient (≥18 years old) Patient admitted to the emergency room of the Nouvel Hôpital Civil in Strasbourg between 06/01/2021 and 12/31/2021 and presenting with typical chest pain <30min or atypical symptoms but non-eliminable cardiac origin. Patient with an initial assessment within the norms (ECG not modified, first troponin negative) and having performed a chest CT scan Patient who has not expressed his opposition to the reuse of his data for scientific research purposes. Exclusion criteria: - Patient who has expressed his opposition to the retrospective reuse of his data for scientific research purposes

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Ability of scan CT to detect coronary calcifications in patients presenting with thoracic pain to the emergency department | Presence on the scanner of calcifications 30 minutes after onset of pain | 30 minutes after onset of pain | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Thoracic pain, Acute coronary event, CT scan, Thoracic scan, Coronary calcifications, Acute Coronary Syndrome
Non-invasive Brain Stimulation for Auditory Verbal Hallucinations in Schizophrenia

Study Overview
=================
Brief Summary
-----------------
The current study investigates the basic principles that underlie the efficacy of transcranial direct current stimulation for chronic auditory verbal hallucinations in schizophrenia in a multimodal design.

Official Title
-----------------
The Mechanism of Non-invasive Brain Stimulation for Therapy of Chronic Auditory Verbal Hallucinations in Schizophrenia

Conditions
-----------------
Auditory Verbal Hallucinations, Schizophrenia

Intervention / Treatment
-----------------
* Device: tDCS


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: diagnosis of schizophrenia chronic auditory verbal hallucinations right-handed Exclusion Criteria: drug abuse other than nicotine severe cognitive deficits severe medical conditions severe neurological disorders severe microangiopathy history of electroconvulsive therapy pregnancy or lactation

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: verum tDCS<br>left-hemispheric tDCS: anode placed midway between F3 and FP1, cathode placed midway between T3 and P3 | Device: tDCS<br>* active vs. sham tDCS left hemisphere<br>* Other names: device: neuroConn tDCS PLUS device;|
| Sham Comparator: sham tDCS<br>left-hemispheric sham tDCS: anode placed midway between F3 and FP1, cathode placed midway between T3 and P3 | Device: tDCS<br>* active vs. sham tDCS left hemisphere<br>* Other names: device: neuroConn tDCS PLUS device;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change of Auditory Hallucination Rating Scale score | Auditory Hallucination Rating Scale score will be assessed at baseline; changes thereof at 3 days after intervention and 3 months after intervention are primary outcome measures | baseline; 3 days after intervention; 3 months after intervention | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Positive And Negative Syndrome Scale | Positive And Negative Syndrome Scale score will be assessed at baseline; changes thereof at 3 days after intervention and 3 months after intervention are secondary outcome measures | baseline; 3 days after intervention; 3 months after intervention |
A Product Performance Evaluation of a Novel Contact Lens for Daily Disposable Use

Study Overview
=================
Brief Summary
-----------------
Evaluation of the clinical performance of a novel Bausch & Lomb daily disposable contact lens when compared to the currently marketed Bausch & Lomb SofLens® daily disposable contact lenses and the currently marketed Johnson and Johnson 1-Day Acuvue Moist contact lenses when worn by adapted soft contact lens wearers on a daily disposable basis.

Conditions
-----------------
Myopia

Intervention / Treatment
-----------------
* Device: Novel Bausch & Lomb daily disposable contact lenses
* Device: Bausch & Lomb SofLens daily disposable contact lenses.
* Device: Johnson and Johnson 1-Day Acuvue Moist contact lenses


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Subjects with VA correctable to 0.3 logMAR (driving vision) or better in each eye. Subjects must have clear central corneas and be free of any anterior segment disorders. Subjects must be myopic and require lens correction in both eyes. Exclusion Criteria: Subjects with any systemic disease affecting ocular health. Subjects using any systemic or topical medications that will, in the Investigator's opinion, affect ocular physiology or lens performance. Subjects wearing monovision, multifocal or toric contact lenses. Subjects with grade 2 or greater slit lamp findings.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Novel Bausch & Lomb Contact Lens<br>Novel Bausch & Lomb daily disposable contact lenses | Device: Novel Bausch & Lomb daily disposable contact lenses<br>* Lenses to be worn and replaced daily for 2 weeks.<br>|
| Active Comparator: SofLens<br>Bausch & Lomb SofLens daily disposable contact lenses | Device: Bausch & Lomb SofLens daily disposable contact lenses.<br>* Lenses to be worn and replaced daily for 2 weeks.<br>|
| Active Comparator: Acuvue<br>Johnson and Johnson 1-Day Acuvue Moist contact lenses | Device: Johnson and Johnson 1-Day Acuvue Moist contact lenses<br>* Lenses to be worn and replaced daily for 2 weeks.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Percentage of Participants With Favorable Responses for the Initial Lens Performance Survey | The initial lens performance survey was administered at the Screening/Dispensing Visit. Scores were captured on a scale from 0 to 100, with 100 being the most favorable score. Favorable responses were defined as scores of 80 or greater. | At dispensing |
The Effect of Virtual Reality Glasses Used During Burn Dressing in Children on Pain, Anxiety and Fear

Study Overview
=================
Brief Summary
-----------------
This work; It was planned as a randomized controlled study to determine the effect of watching cartoons with virtual reality glasses during burn dressing of children aged 5-10 years who applied to the Training and Research Hospital Burn Unit Polyclinic on the feeling of pain, anxiety and fear in children.

Detailed Description
-----------------
The study will be applied to children in the 5-10 group who will undergo burn dressing. During the dressing, children will be watched cartoons with virtual reality glasses and pain, anxiety and fear will be looked at before and after the dressing. The children in the control group will be given routine applications of the clinic.

Official Title
-----------------
The Effect of Virtual Reality Glasses Used During Burn Dressing in Children on Pain, Anxiety and Fear

Conditions
-----------------
Randomized

Intervention / Treatment
-----------------
* Other: Experimental group


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: The child and family agree to participate in the research, The child does not have a disease that causes chronic pain, The child is between the ages of 5-10, 1st and 2nd degree burns of less than 10% of the body surface area of the child, Local burn, no facial burn The child has no mental or neurological disability Failure to intervene in the child with general anesthesia The child has no eye problems Exclusion Criteria: Child and family refusal to participate in the study 3rd and 4th degree burns of more than 10% of the body surface area of the child, The child is less than 5 years old and over 10 years old The child has a mental or neurological disability Intervention of the child with general anesthesia The child has an eye problem

Ages Eligible for Study
-----------------
Minimum Age: 5 Years
Maximum Age: 10 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Experimental group|Experimental group: 26 control group group: 26|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| pain, anxiety, fear scores, | We will evaluate the pain, anxiety, fear score with the Wong Baker Pain Scale before and after dressing in the trial and control group.reality glasses compared to the control group. | July 2022-October 2022 |