Arabin Pessary in Singleton Pregnancy

Study Overview
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Brief Summary
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This was a retrospective study sharing the experience of women high risk for spontaneous preterm birth managed by Arabin pessary.

Detailed Description
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The study recruitment was from 1st January 2013 until 31st December 2019. Inclusion criteria were previous mid-trimester miscarriage and/or preterm birth, previous cervical surgery or short cervical length on routine ultrasound. The primary outcome measure was birth before 34 weeks gestation.

Official Title
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Arabin Pessary Use in Women at High Risk for Preterm Birth: 7 Years' Experience in a Single Tertiary Centre

Conditions
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Previous Mid Trimester Miscarriage, Previous Preterm Birth, Previous Cervical Surgery, Short Cervix on Ultrasound

Intervention / Treatment
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* Device: Arabin pessary


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: all women high risk for spontaneous preterm birth Exclusion Criteria: had Arabin insertion elsewhere delivered elsewhere incomplete record

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Device: Arabin pessary|Arabin pessary was inserted intravaginally electively in women with cervical insufficiency (history based) or as emergency in those with short cervix on ultrasound.|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Birth at or more than 34 weeks | Gestation of birth in percentage that occurred at or more than 34 weeks gestation | From insertion of the Arabin pessary until birth of the foetus | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Type of labour | Type of labour whether spontaneous or induced | From insertion of the Arabin pessary until birth of the foetus | 
| Mode of delivery | Mode of delivery whether vaginal or caesarean section | From onset of labour until birth of the foetus | 
| Median birth weight | Median neonatal birth weight in gram | At birth | 
| Admission into neonatal intensive care unit | The need to admit the neonate to neonatal care intensive care unit at birth | At birth until discharged from the hospital | 
| Mean cervical length | The mean cervical length at insertion of the Arabin pessary | At insertion of the Arabin pessary | 
| Subsequent management | The management of the patients after insertion of the Arabin pessary | From insertion of Arabin pessary until birth of the foetus | 
| Combination with progestogen therapy | Addition of progestogen therapy either vaginally or parenterally | from insertion of Arabin pessary until birth of the foetus | 
| Complications | Antenatal complications such as diabetes, hypertension and rupture of membranes | From insertion of Arabin pessary until birth of the foetus | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Arabin pessary, spontaneous preterm birth