COVID-19 SARS-CoV-2 Antibody Testing Study

Study Overview
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Brief Summary
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SATS is a single site feasibility study to assess the practical and psychological feasibility of using rapid COVID antibody testing of blood obtained from fingertip pin-pricks.

Detailed Description
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SATS is a feasibility study conducted at a single site - King's College London and South London and Maudsley staff working at the Institute of Psychiatry, Psychology and Neuroscience (IoPPN) at Denmark Hill, London, England. The practical and psychological feasibility of using rapid COVID antibody testing of blood obtained from fingertip pin-pricks will be assessed.

Official Title
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COVID-19 SARS-CoV-2 Antibody Testing Study

Conditions
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Healthy

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: King's College Staff member Aged 18 years or over Able to freely give informed consent Exclusion Criteria: The participant may not enter the study if ANY of the following apply: known to have an infectious disease including a current SARS-CoV-2 infection. Any significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the research study, or may influence the result of the research study, or the participant's ability to participate in the research study. Examples of disorders or diseases which would be excluded include: Medically diagnosed bleeding disorder; Medically diagnosed platelet disorder; Anticoagulant medication.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Adult KCL IoPPN Staff<br>Freely consenting Adult KCL Staff attending King's College London, IoPPN, Denmark Hill site will all have an antibody test on finger prick blood. The antibody test will give a rapid result for the presence of IgG or IgM antibodies to COVID-19 | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Acceptability of performing antibody testing procedures involving a capillary blood sample collected via finger-prick | o Acceptability would be represented by the number of participants who consent to and complete the antibody testing procedure. | 1 Year | 
| Test validity of the antibody tests that are performed | the number of completed tests that are valid with a positive/negative IgG/IgM result and confirmed with a positive control line compared with invalid test results as confirmed with a negative control result. | 1 Year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| o Representativeness of participants psychological and behavioural reaction to the testing procedure, their test results, and their willingness to be re-tested. | Assessed by psychometric testing using visual analogue scales | 1 Year | 
| o Representativeness of participants sampled | This would be assessed using demographic data collected from participant | 1 Year |