Evaluation of Perioperative Celecoxib for Hip Arthroscopy

Study Overview
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Brief Summary
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Celecoxib is commonly used for perioperative pain control for certain orthopaedic procedures. It has been shown to be successful in assisting in pain control for knee arthroscopy. It has not previously been studied in hip arthroscopy. This is a double blinded randomized controlled trial to determine the efficacy of celecoxib in perioperative pain control for hip arthroscopy.

Detailed Description
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This study examines the efficacy of perioperative dose of celecoxib in pain management after hip arthroscopy. Perioperative administration of celecoxib has been shown to improve pain control after knee arthroscopy, but this has not yet been studied in the hip. In this study, patients are randomized to receive either 400mg celecoxib or placebo 1 hour prior to undergoing hip arthroscopy surgery. Postoperatively, patients are monitored for pain on the VAS scale, narcotic use, and meeting discharge criteria. The study will enroll 100 patients. Patients are approached for informed consent on the day of surgery. Pain scores, narcotic use, and time to discharge in the celecoxib group are compared to the placebo group.

Official Title
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Evaluation of Perioperative Celecoxib for Hip Arthroscopy

Conditions
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Hip Labral Tears

Intervention / Treatment
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* Drug: Celecoxib
* Drug: placebo


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All patients who are undergoing a hip arthroscopy procedure at Northwestern Memorial Hospital with Dr. Michael Terry. Exclusion Criteria: Pregnant women and any patient under the age of 18 years.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 89 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Intervention<br>Received 400mg celecoxib prior to surgery | Drug: Celecoxib<br>* Received 400mg celecoxib prior to surgery<br>|
| Placebo Comparator: Placebo<br>Received placebo pill prior to surgery | Drug: placebo<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual Analog Score for Pain (VAS) in the Immediate Post Operative Period | The pain VAS is a uni dimensional measure of pain intensity. It is a continuous scale comprised of a 0-10 pain rating. A score of 0 indicates no pain while a score of 10 would indicate extreme pain. | Pre operative on day of surgery, immediately following OR close, 1 hr post operatively, 2 hrs post operatively | 
| Total Narcotic Consumption in the Post Anesthesia Care Unit (PACU) | Monitored consumption of narcotic medications following surgery, measured in morphine equivalents | duration of PACU stay,immediate post op period up to a maximum of 4 hours postoperatively | 
| Time to Discharge Following Surgery | Total time to discharge from OR close following surgery, measured in minutes | time from OR to discharge, up to a maximum of 6 hours postoperatively | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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hip arthroscopy