Evaluation of Architectural Changes in Mandibular Bone Pattern After Functional Treatment by Fractal Dimension Analysis

Study Overview
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Brief Summary
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In this study it was aimed to examine the changes in mandibular bone after functional treatment by using fractal dimension (FD) and cortical thickness (CT) analysis.

Detailed Description
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In this study it was aimed to examine the changes in mandibular bone after functional treatment by using fractal dimension (FD) and cortical thickness (CT) analysis. The study will perform on 42 mandibular retrognathia cases. The treatment group (T), comprised of 30 cases treated with functional appliance for one year in puberty. The control group (C) consists of 12 patients who had insufficient oral hygiene; didn't take any orthodontic treatment for one year. FD and CT analysis will evaluate for both sides. FD measurements will perform on processus condylar, antigonial notch, and ramus regions in the panoramic radiographs. Paired t-test will apply to analyze all between groups (before (T1) and after treatment (T2), before (C1) and after (C2) control). Also, independent t-test wişll use to determine whether there was any difference between the treatment group (∆T=T2-T1) and the control group (∆C=C2-C1).

Official Title
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Evaluation of Architectural Changes in Mandibular Bone Pattern After Functional Treatment by Fractal Dimension Analysis

Conditions
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Orthopedic Disorder

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Males and females were matched. Treatment period of the treatment group was 1 year. Observation period of the control group was also 1 year. All groups had Class II malocclusion (ANB ≥ 5) with the retrognathic mandible in the period of puberty and had no systemic problem and impacted teeth. Monoblock and twin-block appliances were applied to the treatment group. Patients in the control group had insufficient oral hygiene and after oral-care was provided, they were taken into treatment. Exclusion Criteriteria: 1. Radiographic images that do not have sufficient diagnostic quality

Ages Eligible for Study
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Minimum Age: 11 Years
Maximum Age: 13 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Group 1. The treatment group (T)<br>The treatment group comprised of 30 cases treated with functional appliance for one year in puberty. | |
| Group 2. The control group (C)<br>The control group consists of 12 patients who had insufficient oral hygiene; didn't take any orthodontic treatment for one year. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The effect of functional treatment on the cortical structure of the mandible will be investigated by measuring cortical thickness. | the effects of functional treatment with cortical thickness to cortical bone structure | for one months from the beginning of the study | 
| Thanks to fractal dimension analysis, the effect of functional treatment on the trabecular bone structure of the mandible will be examined. | the effects of functional treatment with fractal analysis to trabecular bone structure | for one week from the beginning of the study | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Functional orthodontic appliances, fractal dimension, panoramic radiographs, orthodontics