Predictive Factors for Failure or Success of Endoscopic Treatment of Superficial Colorectal Tumors

Study Overview
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Brief Summary
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To evaluate the long-term complete remission rate (> 12 months) after endoscopic treatment of early neoplastic colorectal lesions.

Detailed Description
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Intra-mucous colorectal neoplasia lesions (or even with minimal mucosal infiltration), formerly treated surgically, are increasingly treated endoscopically. The IPC as a center for interventional endoscopy has been taking care of these lesions for several years. Resection techniques have diversified since the 2000s (polypectomy, monobloc or piecemeal mucosectomy, submucosal dissection ... etc) and the endoscopy team has developed its various techniques within the institute ; Practice has evolved and has not been studied or evaluated in recent years. The purpose of this study is to evaluate practices and to compare results with the literature, and to identify predictive factors for the failure or success of endoscopic treatment of these early neoplastic lesions.

Official Title
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Predictive Factors for Failure or Success of Endoscopic Treatment of Superficial Colorectal Tumors

Conditions
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Superficial Colorectal Tumors

Intervention / Treatment
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* Other: Evaluation of the long-term complete remission rate (> 12 months)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patient having undergone endoscopic resection of a colorectal lesion stage 4 or 5 of the modified Vienna classification during the last 5 years at the institute. Exclusion Criteria: Adenomas with low grade dysplasia Endoscopic control not available

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| endoscopic resection of a colorectal lesion<br>Patient having undergone endoscopic resection of a colorectal lesion stage 4 or 5 of the modified Vienna classification during the last 5 years at the institute. | Other: Evaluation of the long-term complete remission rate (> 12 months)<br>* Evaluation of the long-term complete remission rate (> 12 months)<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Complete long-term remission (> 12 months) | Evaluation of the long-term complete remission rate (> 12 months) | 13 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Absence of residual lesion on early control (3 to 6 months) | Medium-term response rate (3 to 6 months) | 3 to 6 months | 
| Rates of medium and long-term recurrence | Recurrence rate in the medium and long term | 13 months | 
| Management of medium and long-term recurrence | Management of recurrence (endoscopic revision or surgery) | 13 months | 
| Morbidity and mortality rates | Morbidity and mortality rate of endoscopic resection | 13 months | 
| Lymph node or visceral metastatic evolution rate | Rate of pejorative lymph node or metastatic evolution (especially for lesions with microinfiltration of the submucosa) | 13 months | 
| Endoscopic description and anatomopathological results | Endoscopic and / or anatomopathological predictive factors of success (complete long-term remission) | 1 day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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endoscopic resection, colorectal adenomas, Colorectal adenocarcinomas