Body Weight-Based Interval Training in Sedentary Overweight and Obese Adults

Study Overview
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Brief Summary
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Body-weight based interval training (IT) performed 3 times per week will lead to reductions in abdominal adiposity and reduce overall body fat percentage in overweight and obese sedentary adults more effectively than moderate intensity continuous training (MICT). Body-weight interval training will improve exercise capacity (peak VO2) in overweight/obese adults.

Detailed Description
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Participants will be randomly assigned to one of the two home-based exercise groups. The MICT group is the standard care group and will be instructed to walk for 30 minutes, 5 days per week at a moderate intensity. The goal is to accumulate 150 minutes of continuous aerobic exercise each week. Participants will be instructed on the use of the Rating of Perceived Exertion (RPE) scale during baseline testing and will be instructed to reach an RPE of 12-16. A heart rate monitor will be worn to monitor exercise intensity. Heart rate should reach  70% of maximal heart rate. The IT group will perform 5 body-weight exercises in three progressive phases. During the first 2 weeks the circuit will be completed twice, 30 second intervals, 90 seconds of rest. The exercises will be performed on 3 days of the week with at least one day of rest between exercise days (ideally Monday, Wednesday, Friday). The number of repetitions will increase to a maximum of 4 while the interval and rest periods increase to a maximum of 45 seconds each. The total time spent performing intervals by week 8 will be 15 minutes. A 2 minute warm up and 3 minute cool down will be performed, such as jumping jacks or simply walking. A heart rate monitor will be used to measure exercise intensity. Heart rate should reach approximately 90% of heart rate max during the intervals. Participants will be instructed on the use of the Rating of Perceived Exertion scale during baseline testing and will be instructed to reach an RPE of ≥17 during the high intensity intervals.

Official Title
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The Effect of Interval Training Using Body Weight on Body Composition in Sedentary Overweight and Obese Adults

Conditions
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Body Weight Changes, Overweight and Obesity, Physical Activity

Intervention / Treatment
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* Behavioral: Interval Training
* Behavioral: Standard of Care


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adults 18-65 years of age Willing and able to provide informed consent Sedentary, overweight and obese adults (<90 minutes of moderate intensity exercise) BMI 25≤35 Able to safely begin an exercise program Have a smartphone, and willing and able to download and use the Fitbit app Exclusion Criteria: Unable to provide informed consent. Known cardiovascular disease, or uncontrolled hypertension, Diagnosed type 1 or 2 diabetes Women who are pregnant or plan to become pregnant in the next 3-4 months Orthopedic injury/limitation or any other contraindications to exercise. Medications that cause weight gain (steroids, HIV-related medications, etc.), or glucose lowering medications

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Standard Walking<br>This arm is prescribed standard of care exercise prescription; 30 minutes of moderate intensity walking, 5 days/week. | Behavioral: Standard of Care<br>* Walking prescribed to meet current exercise guidelines; 150 minutes per week.<br>|
| Experimental: Interval Training<br>This arm is prescribed body-weight based interval training 3 days per week with progressive increase in exercise intervals and sets. | Behavioral: Interval Training<br>* Interval training is prescribed 3 days per week using 5 body weight exercises in a progressive fashion.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Body fat percent | DEXA derived body fat % | 12 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Weight | Weight in kilograms | 12 weeks | 
| Change in peak VO2 | Peak VO2 in ml/kg/min | 12 weeks | 
| Visceral adipose tissue area | cm^2 | 12 weeks | 
| Thigh adipose tissue area | cm^2 | 12 weeks |