Vibration Induced Reflex Responses and Estimation of TVR

Study Overview
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Brief Summary
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The aim of this study is to estimate tonic vibration latency and whole body vibration reflex latency

Detailed Description
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This study was included 17 patients with spastic spinal cord lesions and 23 healthy control. Soleus T-reflex, soleus H-reflex, soleus tonic vibration reflex (TVR), and reflex muscle response induced by whole body vibration was evaluated this study. To obtain the H-reflex response, the tibial nerve in the popliteal region was stimulated by using a stimulator (FE155 Stimulator HC ADInstrument, Oxford UK) with 1 ms-pulse current. The records was taken with the Ag / AgCl electrodes (Kendall ®Coviden, self-adhesive electrodes) placed on skin according to the SENIAM protocol. To obtain T-reflex response, an electronic reflex hammer (Elcon 100-150 Germany) was used. After H-reflex and T reflex records at rest, to obtain Tonic vibration reflex, local vibration was applied to the Achilles tendon at 50, 85, 140, 185, 235 and 265 Hz. To obtain the reflex response induced by Whole body vibration, vibration was applied at 35, 37, 39, 41, 43 and 45 Hz. Tibial nerve stimulation was performed again to determine Hmax during whole body vibration and local vibration.H-reflex records was taken while the subject is sitting on a chair. The data was recorded with the PowerLab data acquisition device (ADInstrument Oxford UK). For Whole-body vibration, PowerPlate Pro5 (London UK) was used.

Official Title
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Vibration-induced Reflex Responses and Estimation of Tonic Vibration Latency

Conditions
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Muscle, Physiology

Intervention / Treatment
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* Device: vibrator


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria spinal cord injury patients: Spastic spinal cord lesion Patients between the ages of 20 and 45 Exclusion Criteria for spinal cord injury patients Accompanying trauma Lower extremity fracture Lower extremity peripheral nerve lesions Head trauma Autonomic dysreflexia Heterotopic ossification Lesions in calf skin Excessive spasticity (Ashwort4) / Contracture (knee, hip, footbath) Peripheral nerve-vascular diseases / muscle diseases Pressure ulcer (> Grade 2) Inclusion criteria for Control Ages 20 and 45 old years Both sex Healthy volunteers Exclusion Criteria for Control Pregnant women

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Vibrator<br>Local or Whole body vibration was applied at six different frequencies to Healthy control and spastic spinal cord injury. For local vibration, vibration frequencies were 50, 85, 140, 185, 235 and 265 Hz . For whole body vibration, vibration frequencies were 35, 37, 39, 41, 43 and 45 Hz | Device: vibrator<br>* Local or whole body vibration was applied at six different frequencies<br>* Other names: cyclic mechanical loading;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Presynaptic inhibition level | Change in Hmax amplitude during vibration | 1 day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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vibration, muscle spindle, H reflex, tonic vibration reflex