High Level Mobility Training in Ambulatory Patients With Acquired Non-progressive Central Neurological Injury

Study Overview
=================
Brief Summary
-----------------
Brain injuries are a significant cause of loss of movement. It has been shown that physical therapy can help patients to regain movements. The purpose of this study is to see if it is possible to perform a new exercise program that will help patients regain movement. This new exercise program will involve practicing walking, stairs, jumping and running. Participation in this study will involve physical therapy 1 to 2 times a week for 12 visits over 6 to 8 weeks.

Official Title
-----------------
High Level Mobility Training in Ambulatory Patients With Acquired Non-progressive Central Neurological Injury

Conditions
-----------------
Neurological Injury

Intervention / Treatment
-----------------
* Other: Simple Skill Group
* Other: Complex Skill Group


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Referred to physical therapy with an Acquired Non-Progressive Central Neurological Injury (traumatic brain injury, stroke, brain tumor, spinal cord injury) for 3 months or more capacity to consent ability to read and write English at the sixth grade level able to walk twenty meter without physical assistance or an assistive device, however they can use a brace. self-selected gait speed of 0.6 m/s or greater when performing 10 meter walk test. Exclusion Criteria: Adults subjects diagnosed with a progressive central or peripheral neurological disorder or an acute non progressive central neurological disorder (less than 3 months) Subjects who require physical assistance or an assistive device to walk twenty meters or demonstrate self-selected gait speed less than 0.6 m/s Subjects who are already able to run independently in the community Participants who are unable to complete the 12 physical therapy visits at prescribed skill level as established by protocol Participants who reports >4/10 on NPRS with lower extremity weight bearing.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 99 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Standard of care<br> | Other: Simple Skill Group<br>* will practice the following skills as needed: bed mobility, transfer, walking, and stairs.<br>|
| Active Comparator: Simple Skill Group<br> | Other: Complex Skill Group<br>* The program will consist of interventions at the impairments level with an emphasis on core strengthening, functional lower extremity strengthening, balance and endurance training, and at the skill acquisition level. Participants will learn pre-running skills (walking, stairs with handrail, walking backward, walking over obstacles, walking on toes, stairs without handrail, bounding), running skills (force generation in vertical plane: hopping, alternate hopping, running in place in gravity minimized position and against gravity; force generation in horizontal plane: bounding, alternate bounding, open chain movement for swing phase, running) and post running skills (running forward, backward, sideways, skipping, hopping).<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Recruitment Feasibility | measured by the number of individuals who consent to participate. | 2 Years | 
| Training feasibility | Measured by the number of sessions attended by each participant. | 2 Years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
non-progressive central neurological injury