linjc16/ctgov huggingface dataset:
The Role of Audiovisual Biofeedback on Image Quality During 4D Anatomic and Functional Imaging

Study Overview
=================
Brief Summary
-----------------
This study will investigate whether audiovisual biofeedback, in which visual and audio cues are used to regulate the patient's breathing, can increase the image quality of 4D CT and 4D PET scans.

Official Title
-----------------
Investigating the Role of Audiovisual Biofeedback on Image Quality During 4D Anatomic and Functional Imaging

Conditions
-----------------
Lung Cancer

Intervention / Treatment
-----------------
* Device: Real time position management system
* Device: LS PET/CT
* Drug: 18-FDG


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Required for inclusion in this study are: Informed consent Diagnosis of AJCC Stage I-III lung cancer of any histology to be treated using radiotherapy at Stanford Cancer Center Age 18 or greater Painfree in supine position Karnofsky performance status 50 or greater The inclusion of educationally disadvantaged, decisionally impaired or homeless people are allowed if informed consent, in the opinion of the consenting investigator (study PI, co-PI or research nurse), is obtained. Exclusion Criteria: No Pregnant women Stanford employees Stanford students Prisoners will be eligible for the study.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Device: Real time position management system|Device to monitor respiration by using optical monitoring of a marker block placed on the abdomen of the patient.|
|Device: LS PET/CT|PET/CT scanner for acquiring CT and PET images (3D and 4D)|
|Drug: 18-FDG|15mCi|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Measure the difference in number of artifacts on 4D CT scans using audiovisual biofeedback in comparison to Free breathing. | The first, third, fifth seventh and ninth patients accrued to the protocol will have their free breathing studies performed first. The second, fourth, sixth, eighth and tenth patients accrued to the protocol will have their audiovisual (a/v) biofeedback studies performed first. | Day one |
Arterial Tone Influence on Cardiac Output Measured by PRAM

Study Overview
=================
Brief Summary
-----------------
This study evaluates the role of arterial tone in the accuracy of cardiac output (CO) measurement by Pressure Recording Analytical Method (PRAM). Patients receiving noradrenaline who need for clinical reason to change the noradrenaline dose will be enrolled. We use echocardiography as reference method of CO measurement.

Detailed Description
-----------------
Pressure Recording Analytical Method (PRAM) is an arterial pulse contour analysis method for CO measurement. As it is an uncalibrated method, one possible reason for its inaccuracy is rapid changes in arterial tone.

Official Title
-----------------
Influence of Arterial Tone Changes on Cardiac Output Measurement by Pressure Recording Analytical Method

Conditions
-----------------
Cardiac Output, Critically Ill

Intervention / Treatment
-----------------
* Device: MostCare


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: invasive blood pressure monitoring on site need to start or change the dose of noradrenaline infusion for clinical reason Exclusion Criteria: age <18 arrhythmia severe valvular insufficiency pregnancy low quality arterial signal

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Device: MostCare|CO measurement using echocardiography and PRAM before and after noradrenaline dose change due to clinical reason|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes of cardiac output after variation of noradrenaline dose: ECO versus PRAM | Agreement between echocardiography and PRAM in CO measurement during arterial tone changes induced by different dose of noradrenaline | Before and 30 minutes after noradrenaline dose variation |
The CUSA Clarity Bone Tip Study

Study Overview
=================
Brief Summary
-----------------
The aim of the Study is to investigate the clinical performance and surgeon preferences of the CUSA Clarity Bone Tip during skull base surgery with removal of bony, and other cranial calcified tissue.

Official Title
-----------------
Clinical Performance Investigation of the CUSA Clarity Bone Tip for Cranial Skull Base Bone Removal Procedures

Conditions
-----------------
Cranial Skull Base Bone Removal

Intervention / Treatment
-----------------
* Device: CUSABT


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Subject is at least 18 years of age Subject requires a cranial skull base procedure involving removal of bone with ultrasonic aspirator Subject is an appropriate candidate to receive use of the CUSA Clarity Bone Tip product during cranial skull base bone removal surgery, per the study surgeon Subject signed the IRB/EC-approved informed consent form demonstrating that the subject is willing and able to participate in this clinical study and to comply with all study procedures Exclusion Criteria: Subject is currently pregnant or plans to become pregnant prior to the study index surgery Subject has any significant medical condition that in the opinion of the investigator will interfere with protocol evaluation and participation Subject's surgical plan includes utilizing CUSA Clarity Bone Tip for bone removal anywhere besides the cranial skull base in an open craniotomy (e.g. transsphenoidal approach or spinal procedures). Subject is a prisoner or member of a different vulnerable population that should not be included in the study per the investigator or ethics committee. Intra-operative exclusion criteria : Surgeon does not utilize CUSA Clarity Bone Tip for cranial skull base bone removal during surgery or utilizes CUSA Clarity Bone Tip anywhere else besides the cranial skull base

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| CUSABT<br>Subject receives use of the CUSA Clarity Bone Tip product during cranial skull base bone removal surgery | Device: CUSABT<br>* Subject receives use of the CUSA Clarity Bone Tip product during cranial skull base bone removal surgery<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Effectiveness of bone removal to access lesion per surgeon assessment: Multifactorial 5-point Likert scale | Multifactorial 5-point Likert scale (1 (worst) to 5 (best)) | Surgery time |
Yoga Therapy for Adolescents With Juvenile Idiopathic Arthritis

Study Overview
=================
Brief Summary
-----------------
The purpose of the study is to better understand the effects of a yoga program on adolescents with juvenile idiopathic arthritis (JIA). The investigators want to learn whether or not a yoga therapy based program will decrease pain and improve quality of life in patients with JIA. This is an 8-week program with home program of online videos.

Detailed Description
-----------------
This is an 8-week program consisting of weekly yoga therapy classes in a public studio. The classes are led by a pediatric occupational therapist who is also a certified internationally accredited yoga therapist (C-IAYT). The initial and final sessions will include an Rheumatologist MD evaluation including a physician global assessment and joint damage assessment (JADI) and visual assessment (VAS). A Visual Analog Pain Scale will and Peds Quality of Life Questionnaire-Arthritis Module 4.0 will be administered. Each yoga class is 75 minutes to include a set-sequence of postures including breathing exercises and final corpse pose (final relaxation).

Official Title
-----------------
Yoga Therapy for Adolescents With Juvenile Idiopathic Arthritis

Conditions
-----------------
Adolescent Juvenile Idiopathic Arthritis, Yoga Therapy

Intervention / Treatment
-----------------
* Behavioral: yoga


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Adolescents with formal diagnosis of JIA, speak and understand English, can get on/off floor independently. Exclusion Criteria: Dependent on assistive device for ambulation; does not understand English, does not have a diagnosis of JIA.

Ages Eligible for Study
-----------------
Minimum Age: 14 Years
Maximum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Yoga therapy intervention<br>Participants will participate in weekly yoga therapy sessions and have the opportunity to use the home video online. | Behavioral: yoga<br>* 75 minute weekly group yoga classes for 8 weeks. Home program online.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Peds QL-Arthritis Module 4.0 | Measures perceived quality of life for adolescents with arthritis | 8 weeks | 
| Visual Analog Pain Scale | Visual marker of perceived pain | 8 weeks | 
| Visual Assessment | Physician visual assessment | 8 weeks | 
| Joint Damage Assessment (JADI) | assessment of joints | 8 weeks | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
yoga therapy, JIA, quality of life, pain management
Correlation of Volumetric Brain Analysis With Development at 18 Months

Study Overview
=================
Brief Summary
-----------------
The study will correlate the volumes of the brain obtained from magnetic resonance imaging (MRI) scans done at term gestation for infants born prematurely who weighed less than 1000 grams at birth with their corresponding development at 18 months corrected age.

Official Title
-----------------
Volumetric Brain Analysis in the Premature Brain: Correlation With Future Development

Conditions
-----------------
Child Development

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: All premature infants born < 1000 grams who had MRI scans of the brain at term gestation Exclusion Criteria: Any known genetic or chromosomal abnormalities

Ages Eligible for Study
-----------------
Minimum Age: 18 Months
Maximum Age: 2 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
Efficacy of Lidocaine Gel in Reducing Foley Catheter Discomfort in Surgical Patients

Study Overview
=================
Brief Summary
-----------------
This study will evaluate whether lidocaine gel for urinary catheter insertion would decrease pain and discomfort associate with Foley catheters upon awakening from general anesthesia in the post anesthesia care unit. As a secondary objective, the study will evaluate bacterial colony counts from urine obtained from the surgical patients after insertion of the Foley catheter prior to prophylactic antimicrobial administration.

Official Title
-----------------
Exploring the Potential Efficacy of Lidocaine Gel in Reducing Discomfort in Patients Undergoing Surgical Procedures Requiring Foley Catheter Placement

Conditions
-----------------
Urinary Catheter Discomfort in Surgical Patients

Intervention / Treatment
-----------------
* Drug: Lidocaine gel
* Drug: standard gel


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Males requiring catheterization for surgical procedures scheduled for less than 4 hours. Exclusion Criteria: Females, patients with preexisting urological conditions, and infections

Ages Eligible for Study
-----------------
Minimum Age: 19 Years
Maximum Age: 100 Years

Sexes Eligible for Study
-----------------
Male

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Placebo Comparator: Standard Gel<br>Standard gel not containing local anesthetic used to insert urinary catheters. | Drug: standard gel<br>* Standard gel that is used to insert a urinary catheter that does not contain local anesthetic<br>|
| Experimental: Lidocaine Gel<br>lidocaine containing gel uses to insert urinary catheters | Drug: Lidocaine gel<br>* Gel used for insertion of urinary catheter containing local anesthetic to determine if patients have less discomfort postoperatively when this is used<br>* Other names: Urojet;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Decrease postoperative urinary catheter related discomfort | Subject and objective pain scale | Within 1 hour of emergence from general anesthetic | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| decreased incidence of bacteriuria | Urine culture and colony counts | immediate post catheter insertion and at 2 hour time point | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
urinary catheter discomfort
Access to Kidney Transplant of Obese Patients Beginning Dialysis

Study Overview
=================
Brief Summary
-----------------
Obesity is in constant increase all over the world and affects 35% of the global population according to the World Health Organisation. It is associated with other cardiovascular risk factors (particularly hypertension and diabetes) and with high morbi-mortality. It is also responsible for an increase of the risk of developing chronic kidney diseases (CKD). In fact, obese patients represent 25% of the dialysis population and Picardy is one of the most affected areas. However, their access to kidney transplant is still restricted and the reasons are not completely understood.

Official Title
-----------------
Access to Kidney Transplant of Obese Patients Beginning Dialysis

Conditions
-----------------
Kidney Transplant Access, Obese Patients, Dialysis, Comorbidities

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age over 18 years old. Patients with BMI≥30 kg/m2 (for study population) and 25≤BMI≤30 kg/m2(for control population) one month after dialysis initiation. Patients agree with their data collection. Exclusion Criteria: Patients with bariatric surgery history. Patients needed dialysis for graft dysfunction. Data loss.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| patients with BMI≥30 kg/m2<br> | |
| patients with 25≤BMI≤30 kg/m2<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| variation of pre-transplant status two years after the obese patients' dialysis initiation between both groups |  | two years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Kidney transplant access, obese patients, dialysis, comorbidities
Molecular Genetic and Pathological Studies of Anal Tumors

Study Overview
=================
Brief Summary
-----------------
Study the Genetics of Anal Cancer

Detailed Description
-----------------
To determine the status of previously identified anal cancer molecular markers and any correlations with outcome as well as to discover new molecular biomarkers through correlating molecular data with clinical outcome. Study of tissue samples and cells from biopsies of your lesion and blood sample. We hope to learn the role genes and proteins may play in the development of anal cancer. Experiments will be performed using this tissue and blood, include analysis of DNA, analysis of RNA expression levels, analysis of protein levels of important gene products, and development of tissue culture cell lines.

Official Title
-----------------
Molecular Genetic and Pathological Studies of Anal Tumors

Conditions
-----------------
Rectal Cancer, Colon Cancer, Colonic Neoplasms, Anal Cancer

Intervention / Treatment
-----------------
* Other: genetic analysis


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria:Inclusion Criteria: Patients with anal tumors Undergoing surgery for elective colon and rectal surgery Exclusion Criteria:No other patients other than adult patients with anal cancer or high risk for anal cancer refered to Stanford will be enrolled to the study. No Children will be included to the study

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: genetic analysis|standard of care|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Genetic analysis of blood sample as well as tissues , will provide us with any possible tumor marker for a better prognostic indicator. |  | Annual assessment. |
Tobacco Cessation Among Smokers Under Alcohol and/or Cannabis Treatment

Study Overview
=================
Brief Summary
-----------------
Aims: To identify the predictors associated with smoking cessation in smokers under treatment for alcohol and/or cannabis treated in drug treatment centers (DTC). Methodology: Mixed methods project with qualitative and quantitative designs (three studies). Study I discussion groups: of clinical professionals of DTC to explore the barriers/facilitators of these smokers in quitting and the interventions carried out. Study II Prospective cohort of smokers in alcohol and/or cannabis treatment that will be followed-up for 12 months. Sample size: difference in incidence (exposed to cessation interventions versus non-exposed = 12 per 100 years), α = 0.05, β = 0.10, losses = 20% (n = 726). Dependent variables: self-reported and verified tobacco consumption abstinence, quit attempts, motivation, and self-efficacy. Independent variables: age, sex, the substance under treatment. Analysis: incidence, relative risk and simple and multiple logistic regression models (odds ratio and confidence interval, CI, 95%) of quitting. Study III discussion groups: with smokers under alcohol and/or cannabis treatment selected according to their typology. Analysis: of thematic content and triangulation qualitative and quantitative results. Expected results: Characterization of variables that influence tobacco cessation, to improve the design of interventions.

Official Title
-----------------
Tobacco Cessation Among Smokers Under Alcohol and/or Cannabis Treatment

Conditions
-----------------
Tobacco Use, Mental Health Disorder, Substance Abuse Drug, Alcohol Abuse, Cannabis Use, Smoking Cessation

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Smokers (at least 1cig./week) Undertreatment for Cannabis and/or Alcohol Abuse for the first time >=18 years-old Under clinical follow-up Informed consent Exclusion Criteria: Severe cognitive impairment 12-month follow-up not guaranteed

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| self-reported and verified tobacco consumption abstinence | self-reported and verified tobacco consumption abstinence by using CO measurement | at twelve months follow-up | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Motivation to quit | self-reported and scored from a Likert scale from 0 to 10 (0= no motivation 10=high motivation) | at twelve months follow-up | 
| Number of cigarettes per day | self-reported | at twelve months follow-up | 
| Stages of Change to quit | Status of the stages of change to quit according to 5 stages proposed by Prochaska and DiClemente | at twelve months follow-up |
Paracetamol Hypothermia Children

Study Overview
=================
Brief Summary
-----------------
Transient Acetaminophen Induced Hypothermia in Pediatrics Population Undergoing General Anesthesia

Official Title
-----------------
Transient Acetaminophen Induced Hypothermia in Pediatrics Population Undergoing General Anesthesia

Conditions
-----------------
Safety Issues

Intervention / Treatment
-----------------
* Drug: Paracetamol


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: - Exclusion Criteria: -

Ages Eligible for Study
-----------------
Minimum Age: 0 Days
Maximum Age: 3 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Temperature comparison<br> | Drug: Paracetamol<br>* Give paracetamol or placebo and compare temperature<br>|
| Active Comparator: No change<br> | Drug: Paracetamol<br>* Give paracetamol or placebo and compare temperature<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Temperature variation |  | 3 months |