The Efficacy of Alcohol After Betadine and Combination of Alcohol and Betadine on Inflammation Vascular Access

Study Overview
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Brief Summary
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The purpose of this study was to compare the efficacy of combination of alcohol and povidone iodine 10% and Alcohol 70% after povidone iodine 10% on inflammation and infection related to vascular access area in hemodialysis patients.

Detailed Description
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These cases were identified from patient that lack of specific diseases; Non-use of antibiotics or immunosuppressive drugs. That the participants will be selected using convenience sampling method and randomly divided into three groups: combination of alcohol and povidone iodine 10%, Alcohol after and control groups. In the Intervention in one group the vascular access site disinfected with Alcohol(group1) and in group 2, Alcohol and povidone iodine 10% was used to separate were disinfected. Then the patient in a month of inflammation and infection of the vascular access will be monitor. Exclusion criteria: inflammation or fistula failure during the study for any reason other than infection. Sample size determination: Through the pilot study. Date: 02.10.2014 till 02.11.2014 Outcome: Washing with both solution affected on reduce the inflammation and infection of the patient. the efficacy of Alcohol after Betadine and combination of alcohol and Betadine on inflammation and infection related to Vascular access hemodialysis patients.

Official Title
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Mashhad University of Medical Sciences

Conditions
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Complication of Hemodialysis

Intervention / Treatment
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* Other: Alcohol and povidone iodine
* Other: combination of alcohol and betadin


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: absence of inflammatory vascular access site three dialysis sessions per week Exclusion Criteria: patient dies patient withdrew from the partnership

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: alcohol and povidone iodine<br>the efficacy of combination of alcohol and povidone iodine on inflammation related to vascular access | Other: Alcohol and povidone iodine<br>* using from Alcohol and povidone iodine for prevention of inflammation<br>|
| Experimental: combination of alcohol and betadin<br>the efficacy of combination of alcohol and povidone iodine on infection related to vascular access | Other: combination of alcohol and betadin<br>* using from combination Alcohol and povidone iodine for prevention of inflammation<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| effected of betadin and alcohol on inflammation and infection of the patient |  | up to one month |