Northeastern Taiwan Community Medicine Research Cohort

Study Overview
=================
Brief Summary
-----------------
The cohort study on disease prevention and health promotion in the northeastern region of Taiwan is a trial dedicated to large-scale generational research in northeastern Taiwan beginning in the August of 2013. The program aims to develop a comprehensive and integrated approach to disease prevention and community health. The researcher's cohort organizes healthcare outreaches for participants over the age of 20 residing in 64 administrative areas in Keelung city and new Taipei city. The researcher's sessions include a comprehensive health examination, health-related questionnaires, and disease awareness seminars. Biological samples, questionnaire information, and medical data obtained from researcher's participants are stored in researcher's core laboratory. Depersonalized data and samples are shared with partnering trials approved by the Chang Gung Memorial Hospital Institutional review board. The investigators are currently partnered with 18 clinical trials spanning across multiple disciplines such as urology, hepatology, metabolism, physical therapy, and psychology.

Detailed Description
-----------------
The cohort study on disease prevention and health promotion in the northeastern region of Taiwan is a trial dedicated to large-scale generational research in northeastern Taiwan beginning in the August of 2013. The program aims to develop a comprehensive and integrated approach to disease prevention and community health. The researcher's cohort organizes healthcare outreaches for participants over the age in Keelung city and new Taipei city. The researcher's sessions include a comprehensive health examination, health-related questionnaires and disease awareness seminars. Biological samples, questionnaire information, and medical data obtained from the researcher's participants are stored in the researcher's core laboratory. Depersonalized data and samples are shared with partnering trials approved by the Chang Gung Memorial Hospital Institutional review board. The investigators are currently partnered with 18 clinical trials spanning across multiple disciplines such as urology, hepatology, metabolism, physical therapy, and psychology. The investigators are also a member of the national Establish Multi-omics Database of Smart Healthcare for Obesity Therapeutics involving  joint project and the national Remote Medical Monitoring System-Linking Healthcare Industrial Ecosystem-Taiwanese Novel Disease Monitoring Solution initiative. Introduction: This research is conducted in the form of community health care activities. Through regular community health household activities, community residents' awareness of health is improved, and various pathogenic factors are analyzed to strengthen health education, improve living habits, reduce risk factors, and promote the health of community residents. Project purpose: In order to promote community fitness, The investigators will conduct long-term community medicine generation research. This research consists of a series of collaborative projects such as chronic kidney disease, chronic liver disease, metabolic syndrome, depression, dementia, obesity, exercise rehabilitation, etc. In community health care activities, collect biological samples such as blood, urine, feces, etc., as well as questionnaire data. This project will link participants relevant health data to establish a database for the generation of Keelung Chang Gung community medicine research. These data will be provided for analysis of co-operative plans related to generations of research and long-term tracking of participants health.

Official Title
-----------------
A Cohort Study on Disease Prevention and Health Promotion in Northeastern Region of Taiwan

Conditions
-----------------
Cohort Study

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Residing in Keelung city and new Taipei city. Mobile health and mental health Participating in healthcare outreaches Exclusion Criteria: Under 20 years old Participant without judgment Participant has HIV

Ages Eligible for Study
-----------------
Minimum Age: 20 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Participants residing in urban areas<br>Urban residents enjoy convenient transportation, have access to abundant medical resources, have more job opportunities, and are on average younger but are also exposed to more air pollution. | |
| Participants residing in rural areas<br>Rural residents have less access to transportation, medical resources, and job prospects comparatively and are comparatively older. However, Rural residents are exposed to less pollution in general. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Participant died during the observation period. | Investigators keep in touch with participants and invite them to participate in healthcare outreaches every year. | From 2013 Augus to Feb 2021 | 
| Dementia | The AD8 dementia screening interview is used to detect the early signs of dementia. Using the items in the form to check whether participants have similar symptoms, so as to detect and treat them as soon as possible. | From 2013 Augus to Feb 2021 | 
| Chronic Kidney Disease | Chronic kidney disease is a type of kidney disease in which there is gradual loss of kidney function over a period of months to years. | From 2013 Augus to Feb 2021 | 
| Liver cancer | Participant suffers from liver cancer | From 2013 Augus to Feb 2021 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
NTCMRC, Maintenance Project, Health Care Activities