Examination of Cognitive Function in Patients Treated With Subutex

Study Overview
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Brief Summary
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People who addicted to Heroin and other opiates suffer from a disease with approved genetic basis. It causes to a behavioral response as searching and using those drugs even though they know it causes severe damages as physiological, familiar and legal affairs. The popular treatment's goal is to clean the people from any drug. In a medical and pharmacological point of view there is no sense in this approach for all people. This point of view believes that Buprenorphine (Subutex) is a correct pharmacological treatment. The hypothesis of this research is that people using Buprenorphine have difficulties in gaining weight, in sexual and cognitive function (according to subjects' reports)

Detailed Description
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People who addicted to Heroin and other opiates suffer from a disease with approved genetic basis. It causes to a behavioral response as searching and using those drugs even though they know it causes severe damages as physiological, familiar and legal affairs. The popular treatment's goal is to clean the people from any drug. In a medical and pharmacological point of view there is no sense in this approach for all people. This point of view believes that Buprenorphine (Subutex) is a correct pharmacological treatment. The hypothesis of this research is that people using Buprenorphine have difficulties in gaining weight, in sexual and cognitive function (according to subjects' reports) We examine people who stopped opiates and began Buprenorphine. Every participant in the study will have two visits: the first one before receiving Buprenorphine and the second one after 3 months of receiving Buprenorphine.

Official Title
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Examination of Cognitive Function, Weight, Sexual Function in Patients Receiving Treatment With Subutex at 3 Months Without Using Opiates

Conditions
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Opiate Addiction

Intervention / Treatment
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* Other: Sexual, cognitive functional tests and measurement weight


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: People who suffer from addiction problems (opiates) People who willing to to start Buprenorphine treatment People who willing to cooperate with study tests and questionnaires People aged 18 to 70 Exclusion Criteria: People who suffer from any neurocognitive problems People who suffer from mental illnesses People who are having legal guardian

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Subutex group<br>People who used opiates and willing to start with subutex treatment | Other: Sexual, cognitive functional tests and measurement weight<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| ASI quationarry, neurocognitive computerized tests, MMSE test, Sexual function questionnaire and satisfaction questionnaire |  | In 2 visits during the study | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Opiates, Subutex, Buprenorphine, Patients who addicted to opiates