Establishment of Tongue Image Database and Machine Learning Model for Malignant Tumors Diagnosis

Study Overview
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Brief Summary
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The tongue images of malignant tumors and corresponding healthy people will be collected to establish the tongue image database. Deep learning will be carried out by computer and artificial intelligence to construct the early screening, diagnosis, prognosis and prognosis model of various malignant tumors based on tongue image for the diagnosis and treatment of malignant tumors.

Official Title
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A Multi-center Observational Clinical Study Observing the Differences of Tongue Images Between Patients With Malignant Tumors and Healthy People

Conditions
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Malignant Tumor

Intervention / Treatment
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* Other: Tongue images, coating on the tongue and clinical data of patients with malignant tumors and healthy people will be collected.


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 18≤age≤80 Histologically or cytologically confirmed malignant tumor No prior chemotherapy, radiotherapy, biotherapy, immunotherapy or other anti-tumor treatment for malignant tumor Subject volunteers to join the study, Signs informed consent, has good compliance and can cooperate with follow-up Exclusion Criteria: Two or more kinds of malignant tumors at the same time Malignant tumor that has been treated by chemotherapy, radiotherapy, biotherapy, immunotherapy or other anti-tumor therapy Subjects who had other factors that might force them to terminate the research ahead of time, such as the development of other severe disease (including mental disease) that required combined treatment, seriously abnormal laboratory examination value, and family or social factors that might affect the subject safety or experimental data collection, as judged by the researchers

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients with malignant tumors and healthy people<br>Tongue images, coating on the tongue and clinical data of patients with malignant tumors and healthy people will be collected. | Other: Tongue images, coating on the tongue and clinical data of patients with malignant tumors and healthy people will be collected.<br>* Tongue images, coating on the tongue and clinical data of patients with malignant tumors and healthy people will be collected.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The differences of tongue images between patients with malignant tumors and healthy people. |  | 1 year | 
| Overall Survival (OS) |  | 3 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Disease free survival（DFS） |  | 1 year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Malignant tumor, Tongue Image