Supervised Perturbation Training Results in Changes in Balance and Falling in Patients With Multiple Sclerosis

Study Overview
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Brief Summary
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Physical exercise can prevent falls, certain types of exercise may be more effective. Perturbation-based balance training is a novel intervention involving repeated postural perturbations aiming to improve control of rapid balance reactions. The purpose of this study was to estimate the effect of perturbation- based balance training on falls and balance in daily life.Thirty patients with multiple sclerosis (PwMS) will assess with regard to dynamic balance, walking and falling. Patients randomly will allocate to a personalized (PRG) or traditional (TRG) rehabilitation group.

Detailed Description
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Thirty patients with multiple sclerosis (PwMS) will assess with regard to dynamic balance, walking and falling. Patients randomly will allocate to a personalized (PRG) or traditional (TRG) rehabilitation group.

Official Title
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Supervised Perturbation Training Results in Changes in Balance and Falling in Patients With Multiple Sclerosis

Conditions
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Multiple Sclerosis

Intervention / Treatment
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* Procedure: perturbation training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: An age older than 18 years Stable phase of the disease without relapses or worsening in the last three months Referring fear of falling or a history of falls (at least one fall in the last year). Individuals with a high level of balance. Exclusion Criteria: Psychiatric disorders Blurred vision Severe cognitive impairment Severely impaired upright postural control or limited participation in a rehabilitation program Cardiovascular and respiratory disorders.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: training group<br>perturbation balance training | Procedure: perturbation training<br>* exercises for body stability in different positions (bridge, sitting, quadrupedal, half- kneeling, kneeling, standing, monopodalic) performed with visual biofeedback; transfers training performed in front of a mirror; ambulation training with courses drawn on the ground in a straight line and with more complex tracks with visual controlin particular using the protocols seated balance/strength training, standing bal- ance/weight-bearing training, mobility training and closed-chain training;<br>|
| Active Comparator: control group<br>traditional physical therapy that including strengthening and stretching | Procedure: perturbation training<br>* exercises for body stability in different positions (bridge, sitting, quadrupedal, half- kneeling, kneeling, standing, monopodalic) performed with visual biofeedback; transfers training performed in front of a mirror; ambulation training with courses drawn on the ground in a straight line and with more complex tracks with visual controlin particular using the protocols seated balance/strength training, standing bal- ance/weight-bearing training, mobility training and closed-chain training;<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| dynamic balance | the effects of perturbation dynamic balance training assessed with four square step test >15 seconds = increased risk of falls | 6 week | 
| walking | the effects of perturbation dynamic balance training assessed with 10 meter walking test | 6 week | 
| walking | the effects of perturbation dynamic balance training assessed with time up and go test(TUG).A score of 30 seconds or more suggests that the person may be prone to falls | 6 week | 
| falling | the effects of perturbation dynamic balance training assessed with Falling Efficacy Scale(FES). The FES is a 10-item test. On a scale from 1 to 10, with 1 being very confident and 10 being not confident at all. | 6 week | 
| fear of falling | The short FES-I is a 7-item self-report questionnaire for measuring perceived self-efficacy to avoid a fall in various situations | 6 week | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Rehabilitation, Multiple sclerosis, Tailored interventions