Animal Allergy in Korean Veterinary Researcher

Study Overview
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Brief Summary
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The investigators will evaluate sensitization to animal allergens and allergic symptom during contacting animal allergens in Korean veterinary researchers who attend their annual conference. The investigators will compare sensitization to animal allergen and other clinical and occupational factors between subjects who suffer from allergic symptom during contacting animal and those who do not.

Detailed Description
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The investigators will visit annual conference of Korean veterinary researchers. After informed consent, Korean veterinary researchers who attend their conference and agree to enrollment into this study will be asked to respond to questionnaires regarding their gender, age, underlying allergic diseases, family history of allergic diseases, occupation and it's duration, contact animal and contact duration. Subjects will also be requested to report allergic symptom, causal animal and situation of contact including veterinary service, animal experiment, pet ownership, and ingestion if subjects suffer from allergic symptom when subjects contact animal. Then, subjects will also be asked to undergo skin prick test for animal allergens including chicken feather and ten mammal epithelia as well as cow's milk, and hen's egg, four fish flesh and seven animal meats. subjects will be divided into two group, subjects who suffer from allergic symptom during contacting animal and those who do not. Between two groups, sensitization to animal allergens as well as other demographic and occupational factors including gender, age, underlying allergic diseases, family history of allergic diseases, occupation and it's duration, contact animal and contact duration will be compared.

Official Title
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Sensitization to Animal Allergens and Allergic Symptoms During Exposure to Animal Allergens in Korean Veterinary Researcher

Conditions
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Rhinitis, Allergic, Asthma, Dermatitis, Atopic, Urticaria

Intervention / Treatment
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* Other: Animal allergy +
* Other: Animal allergy -


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Veterinary researchers attending their annual conference Exclusion Criteria: Veterinary researchers who receive medication including antihistamine (H1 and H2 blocker), systemic glucocorticosteroid which can effect on the result of skin prick test Veterinary researchers who do not want to participate in this study

Ages Eligible for Study
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Minimum Age: 19 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Subjects with animal allergy<br>Subjects who suffer from allergic symptom during contact with animal | Other: Animal allergy +<br>* Allergic symptom occurs when subject contact animal<br>|
| Subjects without animal allergy<br>Subjects who do not suffer from allergic symptom during contact with animal | Other: Animal allergy -<br>* Allergic symptom does not occur when subject contact animal<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Skin reactivity to animal allergen in skin prick test | Mean diameter of wheal for animal allergen in skin prick test | on the day of survey (day 1) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Underlying allergic disease | Underlying allergic disease including allergic rhinitis, asthma, atopic dermatitis, urticaria, food and drug allergy | on the day of survey (day 1) | 
| Family history of allergic disease | Family history of allergic disease including allergic rhinitis, asthma, atopic dermatitis, urticaria, food and drug allergy | on the day of survey (day 1) | 
| Occupation | Type of occupation including veterinary service and veterinary experiment | on the day of survey (day 1) | 
| Duration of occupation | Duration of occupation (year) | on the day of survey (day 1) | 
| Contact animal | Kinds of animals that subjects contact | on the day of survey (day 1) | 
| Contact time | Duration of animal contact (hour/day) | on the day of survey (day 1) | 
| Causal animal | Animal that provokes allergic symptom when subject contact it | on the day of survey (day 1) | 
| Contact situation | Situation including veterinary service, veterinary research, ingestion and pet ownership in which subject contact animal that provokes allergic symptom | on the day of survey (day 1) | 
| Allergic symptom during contacting animal | Allergic symptom including itchy eyes, nose and skin, rhinorrhea, sneezing, nasal congestion, postnasal drip, dyspnea, wheezing, cough, sputum, chest pain or discomfort, urticaria, rash, and angioedema when subject contact animal | on the day of survey (day 1) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Allergen, Veterinary, Allergy, Animals