Laparoscopic Surgery for Severe Recto-vaginal Endometriosis

Study Overview
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Brief Summary
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To determine the quality of life following the radical excision of recto-vaginal endometriosis.

Detailed Description
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Patients undergoing surgery for severe endometriosis with bowel involvement were asked to complete pre-operative and post operative questionnaires at 2, 6 and 12 months, then 5, 10, 15, 20 and 25 years post operatively. Quality of life measured using the EHP-30 and EQ-5D questionnaires. Bowel symptoms were measured using GIQLI. Dysmenorrhoea, dyspareunia, dyschezia and chronic pain were measured using a visual analogue scale.

Official Title
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Laparoscopic Surgery for Severe Recto-vaginal Endometriosis: A Prospective Cohort Study

Conditions
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Endometriosis Rectovaginal Septum

Intervention / Treatment
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* Procedure: Surgery for severe endometriosis


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All women undergoing planned surgery for severe endometriosis with bowel involvement. Exclusion Criteria: Patients who declined to complete questionnaires for whatever reason and/or have their anonymous data analysed.
Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Surgery for severe endometriosis<br>Consecutive patients undergoing excisional surgery for severe endometriosis with bowel involvement | Procedure: Surgery for severe endometriosis<br>* Consecutive patients undergoing excisional surgery for severe endometriosis with bowel involvement<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Quality of life measured using the Endometriosis Health Profile 30 (EHP-30) and EuroQol-5 dimension (EQ-5D) questionnaires. | Recruitment is continuous | 1 year post operative | 
| Bowel symptoms measured using the Gastro-intestinal Quality of Life Index (GIQLI). | Recruitment is continuous | 1 year post operative | 
| Dysmenorrhoea measured using a visual analogue scale (VAS). | Recruitment is continuous | 1 year post operative | 
| Dyspareunia measured using a visual analogue scale (VAS). | Recruitment is continuous | 1 year post operative | 
| Dyschezia measured using a visual analogue scale (VAS). | Recruitment is continuous | 1 year post operative | 
| Chronic pain measured using a visual analogue scale (VAS). | Recruitment is continuous | 1 year post operative | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Quality of life measured using the EHP-30 and EQ-5D questionnaires. |  | 2 months, 6 months, 5 years, 10 years, 15 years, 20 years, 25 years follow up post operative | 
| Bowel symptoms were measured using GIQLI. |  | 2 months, 6 months, 5 years, 10 years, 15 years, 20 years, 25 years follow up post operative | 
| Dysmenorrhoea measured using a visual analogue scale. |  | 2 months, 6 months, 5 years, 10 years, 15 years, 20 years, 25 years follow up post operative | 
| Dyspareunia measured using a visual analogue scale. |  | 2 months, 6 months, 5 years, 10 years, 15 years, 20 years, 25 years follow up post operative | 
| Dyschezia measured using a visual analogue scale. |  | 2 months, 6 months, 5 years, 10 years, 15 years, 20 years, 25 years follow up post operative | 
| Chronic pain measured using a visual analogue scale. |  | 2 months, 6 months, 5 years, 10 years, 15 years, 20 years, 25 years follow up post operative |