Five-year Mortality Rate in People With Diabetic Foot Ulcer

Study Overview
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Brief Summary
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As the global mortality rate decreases for diabetics patients, further explorations and datas are needed about the specific population of diabetics patients suffering a Diabetic Foot Ulcer (DFU). This study investigates the 5 years mortality rate in patients with a diabetic foot ulcer occurring in 2010.

Detailed Description
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Diabetic foot ulcer (DFU) is an economic burden for many countries around the world. It also induces a dramatic decrease in physical, emotional, and social functioning for patients. Oftenly associated with advanced micro and macrovascular complications, high morbidity and a greater risk of premature death (mainly by Ischemic Heart Disease) occure. Only few studies explored DFU patients' long term survival: the few datas coming from cohorts in the 2000's reported mortality rates around 45% at five years after DFU's diagnosis. But life expectancy in diabetics patients imporved during last decade. So the main objective of our study is to evaluate the diabetics patients' 5 years mortality rate, in whom DFU was diagnosed in 2010. Moreover, our secondary objective is to identify the mortality's predictive factors in 2010.

Official Title
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Five-year Mortality Rate in People With Diabetic Foot Ulcer

Conditions
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Diabetes Mellitus, Diabetic Foot, Diabetes Complications

Intervention / Treatment
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* Biological: blood samples
* Other: Clinical exam and DFU medical cares


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: type 1 or 2 diabetes consultation for new diabetic foot ulcer during the year 2010 Exclusion Criteria: None

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Diabetic patients with DFU<br>Diabetic patients with DFU diagnosed in 2010 | Biological: blood samples<br>* Blood samples drawn during hospitalisations when needed<br>Other: Clinical exam and DFU medical cares<br>* Clinical exam and DFU's medical cares at each visit (planned evry 1 to 3 months), during all the 5 years follow up, or until death.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mortality rate 5 years after DFU diagnosis | Five years after DFU diagnosis, patients are called by phone to enquire their health. If patients are dead, family tell us. If no family is available, the City Hall is called to check the death list. | 5 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Risks factors correlated to mortality rate among DFU patients diagnosed in 2010 | All relevants staisticals associations between mortality rate and DFU diagnosed in 2010 | 5 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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diabetes mellitus, diabetic foot, mortality rate, diabetes complications