Validation of a French Version of the Confusion Assessment Method (CAM)

Study Overview
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Brief Summary
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To validate the French version of the CAM, a multicenter diagnostic study will be conducted. The principle of this study is identical to the study of Inouye which initially validated the CAM in 1990. This is to verify the diagnostic properties of the CAM (French version) compared to the gold standard represented by the confused state of psychiatric diagnosis using the DSM. A representative sample of geriatric patients for whom a delirium is suspected, will be recruited in the various participating centers, patients will undergo two consecutive visits: A visit by a geriatrician, during which the confused state of the patient will be evaluated using the French version of the CAM. A visit by a psychiatrist during which the diagnosis of confusional state will be evaluated using the gold standard criteria of the DSM IV. These two evaluations will be conducted on the same day and blinded from each other. The order of these two procedures will be balanced within each center. This process will allow the calculation of diagnostic parameters of the CAM French version (validation competitive): sensitivity, specificity, positive and negative predictive values .

Official Title
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Validation of a French Version of the Confusion Assessment Method (CAM): a Diagnostic Tool for Acute Confusion Among the Elderly

Conditions
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Confusion, Delirium

Intervention / Treatment
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* Other: Psychiatric evaluation
* Other: Geriatric evaluation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: A family member of the patient, or his/her trusted person must have given his/her informed and signed consent The patient must be insured or beneficiary of a health insurance plan Hospitalization in geriatric short stay OR patient consulting at a geriatric assessment center / memory clinic OR geriatric day hospitalization Patients for whom a state of confusion is suspected during the pre-inclusion visit run-in based on the following criteria: Presence of a cognitive function disorder as defined by a score greater than or equal to 3 on the Short Portable Mental Status Questionnaire (SPMSQ) (Pfeiffer E, 1975) AND / OR Presence of a mood disorder and / or behavior disorder (regardless of duration) according to the patient's family or caregivers Presence of a caregiver who can answer questionnaires concerning activities of everyday life Exclusion Criteria: The patient is participating in another study The patient is in an exclusion period determined by a previous study The patient's family or trusted-person refuses to sign the consent The patient does not understand french Severe aphasia Stay is < = 3 days

Ages Eligible for Study
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Minimum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Study population<br>See inclusion and exclusion criteria. Intervention: Psychiatric evaluation Intervention: Geriatric evaluation A potential intervention order effect will be taken into account by balancing in each center the number of evaluations beginning with the geriatric assessment and those starting with the psychiatric assessment. | Other: Psychiatric evaluation<br>* This evaluation is carried out in several stages: Assessment of cognitive functioning; Interview with a relative; Interview with caregivers; Evaluation of the presence of delirium according to DSM-IV criteria; Evaluation of the presence of anxiety, depressive syndrome, dementia or other DSM IV; Reports of adverse events. A potential intervention order effect will be taken into account by balancing in each center the number of evaluations beginning with the geriatric assessment and those starting with the psychiatric assessment.<br>Other: Geriatric evaluation<br>* This evaluation includes a brief interview with a caregiver, diverse scorings (CAM, Delirium Index, Mini Geriatric Depression Scale, Modified Early Warning Score, Clinical Global Impression sclae, Algo Plus), and adverse event reporting. CAM scoring is carried out by a trained geriatrician and a trained nurse and/or a psychologist. A potential intervention order effect will be taken into account by balancing in each center the number of evaluations beginning with the geriatric assessment and those starting with the psychiatric assessment.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| CAM French Version: diagnostic properties | Sensitivity, specificity, positive predictive value, negative predictive value | Day 0 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Reliability and quality of the french version of the CAM | Parameters of reliability and quality of the tool: Inter-rater Agreement (measured by a coefficient of correlation) between two evaluators: geriatrician and a nurse or psychologist Internal consistency of the questionnaire assessed by calculating Cronbach's alpha Time required for assessment Acceptability by clinicians Tolerance of patients | Day 0 | 
| Feasibility of scoring with the French version of the Delirium Index |  | day 0 | 
| Diagnostic properties of alternative algorithms constructed from items of CAM (French version) |  | day 0 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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French language validation, The Confusion Assessment Method (CAM)