linjc16/ctgov huggingface dataset:
Study of Demographic and Dietary Profile in Patients With Ulcerative Colitis in Upper Egypt

Study Overview
=================
Brief Summary
-----------------
Diet is known to play role in the complex etiology of UC.Patient with UC tend to adapt unguided dietary habits without the guidance of a dietician or physician (Dejong,M.J 2019).so identification of nutritional gaps is needed to facilitate the development of evidence-based dietary guideline and subsequently give correct dietary advice to UC patients(Haskkey,N et al 2017).

Official Title
-----------------
Study of Demographic and Dietary Profile in Patients With Ulcerative Colitis in Upper Egypt

Conditions
-----------------
Diet in Ulcerative Colitis Patients

Intervention / Treatment
-----------------
* Dietary Supplement: Diet


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients with ulcerative colitis diagnosed by clinical Endoscopic and histopathological methods Exclusion Criteria: - Patients with any co morbidity ( HTN,DM,Primary sclerosing cholangitis, as those patients need some restrictions of diet which may affect the prognosis of the disease)
Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Ulcerative patients<br> | Dietary Supplement: Diet<br>* Group of diet types<br>|
| Non ulcerative patients<br> | Dietary Supplement: Diet<br>* Group of diet types<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Study of demographic and dietary profile in patients with ulcerative colitis in upper Egypt | Study of demographic and dietary profile in patients with ulcerative colitis in upper Egypt | A year |
PROgastrine COlon DEpistage

Study Overview
=================
Brief Summary
-----------------
Dosage of progastrin in asymptomatic person participating in colon cancer screening

Detailed Description
-----------------
For anyone who will participate in colon screening at the Princess Grace Hospital of Monaco and who has signed the informed consent document. A blood test will be performed in addition to the screening test to assess the rate of progastrin.

Official Title
-----------------
Dosage of Progastrin in Asymptomatic Person Participating in Colon Cancer Screening

Conditions
-----------------
Colon Cancer Screening, Healthy Person

Intervention / Treatment
-----------------
* Diagnostic Test: progastrin


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: participant in colon cancer screening signing informed consent Exclusion Criteria: any major medical, psychiatric or addictive illness that would affect the informed consent process The consent of a representative is not allowed in this study

Ages Eligible for Study
-----------------
Minimum Age: 50 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Interventional Model Description: Interventional Research, at Risk and Minimal Constraints, Category 2
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: progastrin<br>anyone who will participate in colon screening at the Princess Grace Hospital in Monaco and who has signed the informed consent document | Diagnostic Test: progastrin<br>* PROCODE is an interventional study of category 2 (non-medicinal product), with a minimal risks and restrictions, involving only one blood drawn at the screening of colon cancer.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| progastrin rate | measuring the rate of progastrin in the blood | from 15 days to 2 months (until results are obtained) | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
progastrin, screening, bio-marker, healthy person, early stage
Prospective Evaluation of Idiopathic Pancreatitis: Role of Endoscopic Ultrasonography

Study Overview
=================
Brief Summary
-----------------
The purpose of the study is to determine the best evaluation for patients with idiopathic (unexplained) pancreatitis.

Detailed Description
-----------------
The study evaluates the role of endoscopic ultrasonography, given that the minimally invasive procedures can diagnosis gallbladder disease as well as pancreatitis abnormalities.

Official Title
-----------------
Prospective Evaluation of Idiopathic Pancreatitis: Role of Endoscopic Ultrasonography

Conditions
-----------------
Gallbladder Disease, Pancreatitis

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: All patients referred to the principal investigator for unexplained pancreatitis will be enrolled. Exclusion Criteria: There are no gender nor racial exclusion.

Ages Eligible for Study
-----------------
Minimum Age: 19 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluation of current clinical practice for patients with idiopathic pancreatitis |  | 3 hours | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Endoscopic Ultrasonography, Pancreatitis, EUS
Effect of Probiotic on Constipation

Study Overview
=================
Brief Summary
-----------------
Constipation is a prevalent intestinal disorder. Lactobacillus casei strain Shirota (LcS) shows potential effect on alleviating constipation. This study evaluated the impact of fermented milk containing LcS on stool consistency and frequency. The stool short chain fatty acid and gut microbiota were also assessed.

Official Title
-----------------
Effect of Fermented Milk Containing Lactobacillus Casei Strain Shirota on Chinese People With Constipation

Conditions
-----------------
Constipation

Intervention / Treatment
-----------------
* Dietary Supplement: Lactobacillus casei strain Shirota


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: meet ROME Ⅲ criteria for functional constipation normal body mass index between 18.5 and 29.9 Exclusion Criteria: had a serious disease; used systemic antibiotics or antimycotics medication and antidiarrheal or laxative medication in the 30 days prior to the study; allergic to milk protein; constipated because of organic or neurological lesions; participated in any other studies within 2 months prior to this study.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: LcS intervention<br>Patients with constipation received dietary supplement with Lactobacaiilus casei strain Shirota. | Dietary Supplement: Lactobacillus casei strain Shirota<br>* a bottle of 100 mililiter probiotic dairy beverage containing 10^8 CFU Lactobacillus casei strain Shirota every day after lunch.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| change of stool consistency |  | change from baseline stool consistency at four-week intervention | 
| change of defecation frequency |  | change from baseline defecation frequency at four-week intervention | 
| change of constipation-related symptom scores |  | change from baseline constipation-related symptom scores at four-week intervention | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes in stool short chain fatty acid content |  | change from baseline stool short chain fatty acid content at four-week intervention | 
| Changes in gut microbiota |  | change from baseline gut microbiota at four-week intervention |
The Effectiveness of Vancomycin in Comarison With Cefazolin in Prevention of SSI After Craniotomy

Study Overview
=================
Brief Summary
-----------------
Surgical-site infection is the most commonly reported nosocomial infection in patients undergoing surgery and 3rd most nosocomial infection in hospitalized patients. The SSI is associated with increases of length of hospitalization for 6 days and increases the hospital's cost by $ 300. Because of these, prevention of SSI with appropriate antibiotic is essential.

Official Title
-----------------
The Effectiveness of Vancomycin in Comarison With Cefazolin in Prevention of SSI After Craniotomy

Conditions
-----------------
Elective Craniotomy-candidated Patients

Intervention / Treatment
-----------------
* Drug: Vancomycin
* Drug: Cefazolin


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: age 18 years and above elective surgical patients No pre-surgery infection Do not use antibiotics before surgery Insensitivity to beta-lactam antibiotics Exclusion Criteria: cranioplasty Failure to follow the patient The patient's unwillingness to continue participating in the research project Death of the patient

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: 1st group, receiving vancomycin<br>The 1st group receives vancomycin an hour before craniotomy | Drug: Vancomycin<br>* The 1st group receives vancomycin an hour before craniotomy<br>|
| Active Comparator: 2nd group, receiving cefazolin<br>The 2nd group receives cefazolin an hour before craniotomy | Drug: Cefazolin<br>* The 2nd group receives cefazolin an hour before craniotomy<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| infection rate | compare of infection rate in 2 groups | Until 90 days after admission | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| length of hospitalization | compare the length of hospitalization in 2 groups | Until 90 days after admission | 
| raise of ESR & CRP | compare the raise of ESR & CRP in 2 groups | Until 90 days after admission | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
SSI, elective Craniotomy, Vancomycin, Cefazolin, Antibiotic
Intervention to Reduce Falls Incidence

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to determine the effectiveness of a multifactorial intervention program to prevent falls among the elderly as compared to a brief intervention.

Detailed Description
-----------------
The objective of this research is to verify if a simple multifactorial intervention program that is applicable in PC settings is more effective to decrease fall incidence than a brief advice for community-living people aged 70 or older.

Official Title
-----------------
EFFECTIVENESS OF A MULTIFACTORIAL INTERVENTION PROGRAM TO REDUCE FALLS INCIDENCE AMONG COMMUNITY-LIVING ELDERLY PEOPLE

Conditions
-----------------
Patient Fall

Intervention / Treatment
-----------------
* Device: multifactorial


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients residing in the community Exclusion Criteria: to be institutionalized Immobilized or bedridden Present a terminal disease or severe psychiatric illness Have contraindications to physical exercise

Ages Eligible for Study
-----------------
Minimum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Multifactorial intervention<br>Multifactorial intervention to prevent falls | Device: multifactorial<br>* individual advice, information leaflet, physical exercise workshop and home visits<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| fall incidence rate |  |  | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Falls, Prevention, Elderly
Study Medication Adherence and Its Determinants in Chronic Disease Through the Example of Methotrexate in Chronic Inflammatory Rheumatism

Study Overview
=================
Brief Summary
-----------------
The aim of this study is 1) To describe the level and determinants of methotrexate adherence in patients with chronic inflammatory rheumatism (rheumatoid arthritis, spondyloarthritis and psoriatic arthritis) in the department of rheumatology in the Nîmes University Hospital

Conditions
-----------------
Rheumatic Diseases

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: treated by methotrexate patients with chronic inflammatory rheumatism (rheumatoid arthritis, spondyloarthritis and psoriatic arthritis) Exclusion Criteria: methotrexate for other diseases

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Medication Adherence Measure= Morisky scale |  | day 0 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Chronic inflammatory rheumatism
Study of Biomarker From Blood and Tissue of Head and Neck Carcinoma

Study Overview
=================
Brief Summary
-----------------
The aim of the study is to find for one or more serum or tissue markers of molecular biology in head and neck cancer patients used for early diagnosis, predicting prognosis and being sensitive to chemotherapy and radiotherapy

Detailed Description
-----------------
Head and neck malignant tumors, especially nasopharyngeal carcinoma in southern China with the high incidence, its incidence, treatment, prognosis or tumor markers in serum has been a hot research with little progress.In our study, we collect NPC-based collection including the blood samples of laryngeal, hypopharyngeal cancer, separating serum and white blood cells stored in -80 degrees，while tissues are frozen in liquid nitrogen and embedded in paraffin。 Patient treatment and prognosis are combined in order to find for markers of molecular biology used for early diagnosis, predicting prognosis and being sensitive to chemotherapy and radiotherapy.

Official Title
-----------------
Study of Previously Collected Blood and Tissue Samples From Patients With Nasopharyngeal Carcinoma,Laryngeal Carcinoma and Hypopharyngeal Carcinoma

Conditions
-----------------
Laryngeal Neoplasms, Pharyngeal Neoplasms

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: all of nasopharyngeal carcinoma hypopharyngeal carcinoma or laryngeal carcinoma visited at ENT department of NanFang hospital Exclusion Criteria: all of above patients whose anticipated survival duration were less than 6 months

Ages Eligible for Study
-----------------
Minimum Age: 15 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Laryngeal Neoplasms, Pharyngeal Neoplasms
Identifying Cricothyroid Membrane With Ultrasound

Study Overview
=================
Brief Summary
-----------------
Cannot-intubate cannot-ventilate situations in healthy children are uncommon but are often associated with poor outcome. We studied the learning curves of inexperienced trainees for identifying cricothyroid membrane with ultrasound in pediatric patients. After watching an instructional video, 30 trainees performed 5 cricothyroid membrane identification on pediatric patients undergoing general anesthesia. We analysed their learning curves relative to performance time and ultrasound anatomy of cricothyroid membrane and relative structures.

Official Title
-----------------
Learning Curve of Inexperienced Trainees for Identifying Cricothyroid Membrane With Ultrasound in Pediatric Patients

Conditions
-----------------
Ultrasound

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: pediatric patients undergoing general anesthesia Exclusion Criteria: previous history of tracheostomy previous history of operation on neck

Ages Eligible for Study
-----------------
Maximum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Performance time for identifying cricothyroid membrane with ultrasound |  | from immediately after anesthetic induction to end of surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| ultrasound anatomy of cricothyroid membrane | depth from skin surface, thickness, diameter, relative vessels | from immediately after anesthetic induction to end of surgery |
Effect of Dehydroepiandrosterone Administration in Patients With Poor Ovarian Response According to the Bologna Criteria

Study Overview
=================
Brief Summary
-----------------
Women with low ovarian reserve typically respond less well to the drugs used to stimulate the ovary during IVF treatment and produce fewer eggs and, as a result, are less likely to fall pregnant either naturally or after fertility treatment. The ideal stimulation regimen for poor responders is currently unknown. Dehydroepiandrosterone (DHEA) has been reported to improve pregnancy chances for poor responders, and is now utilized by approximately one third of all IVF centers world-wide. However, the current clinical evidence for DHEA on improvement of ovarian response and IVF outcome is insufficient. The validity of the results of the former studies, especially the varied inclusion criteria used to specify poor responders, is a subject of debate. Recently a uniform definition on poor ovarian response, the Bologna criteria, has been proposed by the European Society for Human Reproduction and Embryology(ESHRE). However, no studies have been performed study to evaluate the potential effects of DHEA supplementation according to these standards. The purpose of this study is to assess the impact of DHEA supplementation on IVF outcome of poor ovarian responders that fulfill the Bologna criteria.

Conditions
-----------------
Infertility

Intervention / Treatment
-----------------
* Drug: DHEA


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with poor ovarian response according to the Bologna criteria Exclusion Criteria: women aged > 45 years or baseline follicle stimulating hormone(FSH)levels >40 IU/l.

Ages Eligible for Study
-----------------
Minimum Age: 23 Years
Maximum Age: 45 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| DHEA administration,no treatment<br>The patients of study group received DHEA 25 mg orally,three times a day before the IVF cycle. Except for IVF, the control group of patients did not receive any pre-treatment. | Drug: DHEA<br> <br> * Other names: dehydroepiandrosterone;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| ongoing pregnancy rates |  | 12 weeks after gestation. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Clinical pregnancy rate |  | 28 days after the embryo transfer | 
| the number of retrieved oocytes |  | 36-37 hrs after hCG administration | 
| Fertilization rate |  | on day 1 after oocyte retrieval | 
| Cleavage rate |  | on day 2 or 3 after oocyte retrieval | 
| Implantation rate |  | 28 days after the embryo transfer |