A Study on the Prospective Cohort Library of COVID-19 in Southeran

Study Overview
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Brief Summary
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This is a multi-centre population-based follow-up study for all 504 patients with laboratory-confirmed COVID-19. This study establishes a standardized and structured clinical database to provide complete and multidimensional clinical diagnosis and treatment data of novel coronavirus pneumonia, which also support future epidemiological, infectious disease study and patients' prognosis, by collecting clinical data and the related data of patients with novel coronavirus pneumonia in Southern Zhejiang province.

Detailed Description
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The follow-up information will be collected in one-month, three-month, six-month and one-year after discharge. Information about symptoms, radiographic and laboratory findings, lung function, SF-36 QUESTIONNAIRE, antibody of COVID19，result of RT-PCR Test and suvival information will be collected through all time frames.

Official Title
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A Study on the Prospective Cohort Library of Novel Coronavirus Pneumonia in Southeran

Conditions
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Follow-up, COVID-19, Infectious Diseases, Respiratory

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All patients with laboratory-confirmed COVID-19 in Wenzhou Exclusion Criteria: Suspected cases of COVID-19
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 36-Item Short Form Survey Instrument (SF-36) | sum score of SF 36 form in each time frame | one month, three month, six month and one year after discharge, minimum score | 
| the value of FEV1 by lung function test |  | one month, three month, six month and one year after discharge | 
| the ratio of FEV1 to FVC by lung function test |  | one month, three month, six month and one year after discharge | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the predicted value of FEV1 by lung function test |  | one month, three month, six month and one year after discharge | 
| the predicted ratio of FEV1 to FVC by lung function test |  | one month, three month, six month and one year after discharge | 
| Lymphocyte value | laboratory result | one month, three month, six month and one year after discharge | 
| Neutrophil value | laboratory result | one month, three month, six month and one year after discharge | 
| DDI value | laboratory result | one month, three month, six month and one year after discharge | 
| the proportion of applying ACEIs/ARBs medication | collect the number of applying ACEIs/ARBs medication and calculate the proportion | from the date of hospital admission to the day of hospital discharge | 
| number of clinical symptoms after hospital discharge | clinical symptoms | one month, three month, six month and one year after discharge | 
| number of cases returning to positive result in RT-PCR test |  | one month, three month, six month and one year after discharge | 
| Number of positive outcome of IgG for antibody of COVID-19 |  | one month, three month, six month and one year after discharge |