Evaluation of Factors That Cause Secondary Brain Damage on Mortality and Morbidity in Patients Undergoing Emergency Surgery Due to Head Trauma.

Study Overview
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Brief Summary
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Traumatic brain injury is combination damage that occurs as a result of a chain reaction of various metabolic events that develop after primary damage caused by trauma. Pathological events such as lactic acidosis, electrolyte imbalance, increased inflammation that occur during traumatic brain injury leads to poor prognosis in patients. The retrospective study was conducted to investigate the effect of factors that may cause secondary damage, especially electrolyte imbalance and blood glucose levels, on mortality and morbidity in patients undergoing emergency surgery due to head trauma.

Official Title
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Evaluation of Factors That Cause Secondary Brain Damage on Mortality and Morbidity in Patients Undergoing Emergency Surgery Due to Head Trauma.

Conditions
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Brain Injuries

Intervention / Treatment
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* Other: factors evaluation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients who admitted to Bursa Uludag University hospital between 2013 and 2018 patients diagnosed with traumatic brain injury and operated within the first 24 hours after admission Exclusion Criteria: pediatric patients patients that operated after 24 hour of admission

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Healthy Group<br>Patients who had been treated and recovered physically and gained cognitive functions completely. | Other: factors evaluation<br>* They investigated mortality and morbidity in patients who underwent emergency operation within 24 hours after traumatic brain injury.<br>|
| Sequel Group<br>Patients who could not gain their physical and cognitive functions. | Other: factors evaluation<br>* They investigated mortality and morbidity in patients who underwent emergency operation within 24 hours after traumatic brain injury.<br>|
| Exitus Group<br>Patients who did not respond to the treatments and lost their lives within 28 days of admission. | Other: factors evaluation<br>* They investigated mortality and morbidity in patients who underwent emergency operation within 24 hours after traumatic brain injury.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| mortality and morbidity in patients who underwent emergency operation within 24 hours after traumatic brain injury | It seems that secondary damage caused by metabolic events like eletrolyte imbalance in patients with head trauma should always keep in mind. If they encounter these situations, they should treat the patient and do replacements immediately. | 5 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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secondary brain damage, electrolyte imbalance, head trauma