Music to Reduce Use of Smoking in Patients With Schizophrenia

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to explore the impact of self-selected music listening which targets disrupting the reward process maintaining smoking and additionally attenuating the reward processing deficits associated with schizophrenia. Five participants with schizophrenia/schizoaffective disorder who smoke/nicotine will participate in an individual session of self-selected music listening for a half an hour.

Official Title
-----------------
Music to Reduce Use of Smoking in Patients With Schizophrenia

Conditions
-----------------
Schizophrenia, Nicotine Dependence, Smoking, Tobacco

Intervention / Treatment
-----------------
* Behavioral: Music session


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: clinician verification diagnosis of Schizophrenia or Schizoaffective Disorder smoked at least 10 cigarettes per day for the past month score of 4 or more on the Fagerstrom Test for Nicotine Dependence73 psychiatric stability (e.g., no psychiatric hospitalizations within the last year, no expectation for medication change during study participation, no active suicidal ideation, no symptoms that interfere with ability to participate in study activities) the capacity to participate in the informed consent process Exclusion Criteria: being medically unstable (e.g., medical condition that requires frequent medical appointments or hospitalizations and interferes with ability to participate in study activities) report active substance abuse or testing positive drug or alcohol use taking bupropion, varenicline, nicotine replacement products and/or involved in any other smoking cessation treatment participating in any treatment or activity that includes music as a focus having a seizure disorder, other neurological illnesses, or a family history of seizures

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Supportive Care
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Schizophrenia Patients<br>Clinician verification diagnosis of Schizophrenia or Schizoaffective Disorder | Behavioral: Music session<br>* Participants will be asked to refrain from smoking from 24 hours before the music listening session as confirmed by breath carbon monoxide level <6 ppm on the day of the session. They will be contacted by phone or in person at the clinic as a reminder prior.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Snaith-Hamilton Pleasure Scale (SHAPS) | Measures Pleasure Pre Music Session | 1 Day | 
| Snaith-Hamilton Pleasure Scale (SHAPS) Post Music Session | Measures Pleasure Post Music Session | 1 Day | 
| Pleasure Rating Scale (PRS) | Measures Pleasure Pre Music Session | 1 Day | 
| Pleasure Rating Scale (PRS) Post Music Session | Measures Pleasure Post Music Session | 1 Day | 
| Questionnaire of Smoking Urges-Brief (QSU-B) | Measures Cravings Pre Music Session | 1 Day | 
| Questionnaire of Smoking Urges-Brief (QSU-B) Post Music Session | Measures Cravings Post Music Session | 1 Day | 
| Minnesota Nicotine Withdrawal Scale (MNWS) | Measures Withdrawal Pre Music Session and Post Music Session | 1 Day | 
| Minnesota Nicotine Withdrawal Scale (MNWS) Post Music Session | Measures Withdrawal Post Music Session | 1 Day | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Schizophrenia