Accuracy of Open-source Software in Semi-automatic 3-Dimensional Reconstruction of the Mandible

Study Overview
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Brief Summary
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Concomitant to the evolution of CBCT devices, several post-processing software packages were developed for producing 3D-printed models of anatomical structures. In the last few years, several open-source software used as an alternative to commercial software for 3D reconstruction of anatomical structures such as the mandible. However, no sufficient evidence validating the accuracy of this open-source software.

Detailed Description
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3D rendering of craniomaxillofacial structures is based on the segmentation process. Semi-automatic segmentation has been pointed out as the technique of choice since it combines the high efficiency and repeatability of the automatic methods with the experience of an operator. Although the creation of 3D models is very important, it is still not a common procedure, since commercial software often requires higher electronic computer power and is licensed by its manufacturer, increasing the financial costs. In the last few years, several open-source software can be obtained for free such as ITK-Snap and 3D Slicer, which could provide more economical options for clinicians or researchers in patient management. However, no sufficient evidence validating the accuracy of this open-source software in detecting the volumetric and morphological characteristics of craniomaxillofacial structures.

Official Title
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Accuracy of Open-source Software in Semi-automatic 3-Dimensional Reconstruction of the Mandible: A Validity and Reliability Study

Conditions
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Segmentation; Bone

Intervention / Treatment
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* Device: Semiautomatic segmentation of open-source software


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Good quality CBCT scans. Field of view (FOV) including the whole mandibular bone. Absence of artifacts, dental implants, craniofacial deformities, and temporomandibular disorders. Exclusion Criteria: Low-quality CBCT scans. FOV not including the whole mandibular bone. Presence of artifacts, dental implants, craniofacial deformities, and temporomandibular disorders.
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| CBCT Dicom files of patients<br>CBCT Dicom files of patients will be used for measurements of mandibular bone volume by open-source software. | Device: Semiautomatic segmentation of open-source software<br>* Semiautomatic segmentation of open-source software is accurate as of the manual segmentation of commercial software.<br>* Other names: 3D Slicer software;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Validity and reliability of CBCT open-source software (ITK-Snap and 3D Slicer) semiautomatic segmentation in Volumetric measurement of mandibular bone. | The volume calculation function tool of the dedicated CBCT open-source software (ITK-Snap and 3D Slicer) will be used to measure the mandibular bone volume. | 1 year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Open source software, Segmentation, Mandible