linjc16/ctgov huggingface dataset:
Prevalence of Gummy Smile and Its Causes Among the Egyptian Population.

Study Overview
=================
Brief Summary
-----------------
prevalence of gummy smile among the Egyptian population

Detailed Description
-----------------
prevalence of gummy smile among Egyptian population in patients attending the kasr el aini hospital

Official Title
-----------------
Prevalence of Gummy Smile: Cross-Sectional Study on A Sample of Egyptian Patients

Conditions
-----------------
Gummy Smile

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients attending El kasr el Aini hospital at the department of periodontology. patients whose above 18 years old of both genders patients consulting the outpatient clinic provide informed consent Exclusion Criteria: less than 18 years old patients having problems opening their mouth or undergoing inter maxillary fixation where oral examination will not be possible patients diagnosed with psychiatric problems or intoxicated with alcohol or drugs patients with gingival hyperplasia patients with extracted maxillary anterior teeth

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| prevalence of gummy smile | To detect the prevalence of gummy smile among Egyptian population | through study completion, an average of 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| determining associated risk factors and classifying them onto further sub analytical groups | all the causes prevalence within the sample will be calculated | through study completion, an average of 1 year |
Algorithms in a Simulated Difficult Intubation Scenario

Study Overview
=================
Brief Summary
-----------------
This is a non-human study, conducted in a simulation environment, with simulator manikins, and volunteers from anaesthesia. Trainees in their first 2 years of anaesthetics training will be randomised to a control group, a group following the Difficult Airway Society UK's Guidelines and the Australian Difficult Airway management algorithm. A simulated difficult airway will be created during the induction of anaesthesia. The investigators will examine adherence to guidelines, which would have been provided to participants before the experiment, as well as compare their performance with the guidelines.

Official Title
-----------------
A Comparison of the Difficult Airway Society (UK) and Australian Patient Safety Foundation Crisis Algorithms for Difficult Intubation in a Simulated Difficult Intubation Scenario

Conditions
-----------------
Airway Management

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Anaesthetists in first 2 years of training Exclusion Criteria: Those who decline invitation to participate
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Control,<br>Control | |
| DAS: Difficult Airway Society, UK<br>DAS difficult airway algorithm | |
| Australian<br>Australian difficult airway algorithm | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Time to safe oxygenation for manikin |  | Variable |
Self Management Programme on the Sustained Attention and Sleep Quality of the Nurses

Study Overview
=================
Brief Summary
-----------------
The aim of this study is to examine the effect of the nurse-supported self-management program on the sustained attention and sleep quality of night shift nurses. The self-management program consists of training and incentives for night shift nurses to gain healthy eating habits and improve their sleep health.

Official Title
-----------------
The Effect of Nurse-Supported Self Management Programme on the Sustained Attention and Sleep Quality of the Nurses Working at Night Shift

Conditions
-----------------
Sleep Quality, Attention, Nurses

Intervention / Treatment
-----------------
* Behavioral: Nurse-Supported Self Management Programme


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Nurses working in shifts Those between the ages of 18-65 Those who agree to participate in the study. Exclusion Criteria: Pregnant and having suspicion of pregnancy Having vision and hearing problems Having diagnosed sleep disorder Having a chronic disease that will prevent participation in the study Having a diagnosed mental health problem

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Experimental Group<br>Experimental Group | Behavioral: Nurse-Supported Self Management Programme<br>* Training and incentives to improve nutrition habits and sleep health.<br>|
| No Intervention: Control Group<br>Control Group | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Sustained Attention | Psychomotor Vigilance Test | First Month | 
| Sleep Quality | Pittsburgh Sleep Quality Index (PSQI) | First Month | 
| Sleepiness | Epworth Sleepiness Scale | First Month |
Three Year Follow up of a Randomised Controlled Trial (RCT) of an Intervention for Tobacco Dependence Among Those With a Psychotic Illness

Study Overview
=================
Brief Summary
-----------------
This is a three year follow up of a previous study where researchers at UNSW and UNewc asked smokers with serious mental health problems to participate in a 12-month study, to assess whether intervention could assist people experiencing mental illness reduce their tobacco smoking.

Detailed Description
-----------------
Between 2001 and 2003, the School of Public Health and Community Medicine at the University of New South Wales carried out a large study with the Centre for Mental Health Studies at the University of Newcastle. The project asked people with serious mental health problems, who also smoked cigarettes, to participate in a 12-month study, which involved completing several questionnaires/other assessments over that time with a member of the research team. Around half of the participants in this study also received treatment for their smoking from the research team. This treatment involved weekly therapy with one member of the research team, and covered the relationship between smoking and mental illness, teaching people to cope with desires to smoke, how to recognise and avoid high risk situations for smoking, and how to plan alternative ways of coping with those situations where smoking usually occurred. In addition, nicotine patches were also available to assist people who made the decision to reduce their smoking. This study hoped to learn whether this new treatment could assist people experiencing mental illness reduce their tobacco smoking. After three years, previous participants were invited to participate in another follow-up assessment to check-in with their current situation, their mental health and levels of smoking.

Official Title
-----------------
Three Year Follow up of a Randomised Controlled Trial of an Intervention for Tobacco Dependence Among Those With a Psychotic Illness

Conditions
-----------------
Psychotic Disorder, Behavior, Addictive

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Previous participants from the original study

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 67 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
Tranexamic Acid in Major Vascular Surgery

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to determine whether tranexamic acid is effective in reducing intraoperative blood loss and necessity for haemotransfusion in patients undergoing open abdominal aortic aneurysm repair

Official Title
-----------------
Tranexamic Acid in Major Vascular Surgery. A Randomized Placebo-controlled Trial.

Conditions
-----------------
Blood Loss, Surgical

Intervention / Treatment
-----------------
* Drug: tranexamic acid diluted in 100 ml of saline solution (loading dose)
* Drug: tranexamic acid undiluted (continous infusion)
* Drug: Placebo


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age > 50 Able to give written informed consent Undergoing open abdominal aortic aneurysm repair Exclusion Criteria: Patients participating in a pharmaceutical clinical trial in the last 3 months Urgent/emergent surgery Allergy/intolerance to tranexamic acid History of seizures Acute Venous or Arterial Thrombosis Fibrinolytic conditions due to consumption coagulopathy Disseminated intravascular coagulation Haematuria Visual disturbances

Ages Eligible for Study
-----------------
Minimum Age: 50 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Tranexamic Acid<br>A 500 mg loading dose of tranexamic acid diluted in 100 ml of saline solution will be slowly administered intravenously to patients 20 minutes before surgery, followed by a continuos infusion of 250 mg/h of tranexamic acid from surgical incision until skin closure. | Drug: tranexamic acid diluted in 100 ml of saline solution (loading dose)<br> <br> Drug: tranexamic acid undiluted (continous infusion)<br> <br> |
| Placebo Comparator: Placebo<br>Saline | Drug: Placebo<br>* Saline<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Blood loss (milliliters) |  | intraoperative (from skin incision to skin closure) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of packed blood red cells transfused |  | hospital stay (an average of one week) | 
| Occurrence of thromboembolic events (of any nature) |  | 28-days and one year after surgery | 
| Mortality |  | 28-days and one year after surgery |
Mortality Score in Elderly Patients With Colon Cancer

Study Overview
=================
Brief Summary
-----------------
CR-POSSUM is one of the most used surgical scores to predict mortality after colorectal surgery. Its main drawback is the requirement of intraoperative variables, whose collection is time-consuming and prevents from obtaining a purely preoperative risk assessment. The primary aim of the study is to develop a new surgical score using preoperative parameters to predict 30-day mortality after colon cancer surgery in the elderly population. The secondary objective is to analyze its efficacy compared to CR-POSSUM.

Detailed Description
-----------------
Patients aged 80 and older undergoing surgery for colon cancer from 2011 to 2017 in an Italian hospital were retrospectively selected. MECC score [Mortality in Elderly patients with Colon Cancer] was calculated summing up the scores relating to: arterial saturation of O2, Systolic Blood Pressure, Heart Rate, WBCs, Albumin, Creatinine. Once CR-POSSUM was calculated, the two scores were compared.

Official Title
-----------------
Score for the Prediction of Mortality Risk After Surgery for Colon Cancer in a Case Series of Elderly Patients

Conditions
-----------------
Mortality, Surgery, Colon Cancer

Intervention / Treatment
-----------------
* Procedure: Colon Surgery


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients aged 80 and above having elective and emergency colonic resection for colon cancer via open, laparoscopic and converted approaches Exclusion Criteria: Surgical resections for rectal cancer and surgical procedures for non-neoplastic colon pathologies

Ages Eligible for Study
-----------------
Minimum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: Colon Surgery|Right, left colon surgery, transverse colon surgery, multiple colon surgery in open and minimally invasive surgert|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| New surgical score using preoperative parameters to predict 30-day mortality after colon cancer surgery in the elderly population | MEC Score (arterial saturation of O2, Systolic Blood Pressure, Heart Rate, WBCs, Albumin, Creatinine) for the evaluation of the risk of in-hospital mortality occurred during hospitalization up to 30 days | Up to 30 days after surgery | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
colon cancer, surgery, mortality, elderly, scoring system
Effects of Inspiratory Muscle Training on Dyspnea in Subjects With Chronic Obstructive Pulmonary Disease

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to determinate whether inspiratory muscle training (IMT) associated with a conventional respiratory rehabilitation program is more effective than a conventional respiratory rehabilitation program alone,on Dyspnea in chronic obstructive pulmonary disease (COPD) subjects with a normal maximum inspiratory pressure (IP > 60 cmH2O).

Detailed Description
-----------------
Dyspnea is the main complaint of patients with COPD. Dyspnea is explained largely by the distension, objectified by measuring inspiratory capacity (IC), which places the diaphragm at a disadvantage to be effective, which raises the sensation of dyspnea. Currently, inspiratory muscles training is recommended by the French-language Society of Pneumology, in case of an objective reduction of the strength of these muscles (corresponding to maximum inspiratory pressure <60 cm H20).

Official Title
-----------------
Effects of Inspiratory Muscle Training Combined With a Pulmonary Rehabilitation Program Versus a Program of Pulmonary Rehabilitation Alone on Dyspnea: a Randomized Trial

Conditions
-----------------
Chronic Obstructive Pulmonary Disease

Intervention / Treatment
-----------------
* Other: Inspiratory muscle training


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patient with COPD Hospitalized in the pulmonary rehabilitation unit in the hospital of Morlaix, with a 3 weeks pulmonary rehabilitation course Exclusion Criteria: Pneumonectomy, Lobectomy less than 6 months Cardio-pulmonary anomaly Max inspiratory pressure < 60 cm H2O

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: standard<br>conventional respiratory rehabilitation | |
| Experimental: IMT<br>Inspiratory muscle training and conventional respiratory rehabilitation | Other: Inspiratory muscle training<br>* Inspiratory muscle training<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Dyspnea measure | Measure of changes in Mutidimentionnal Dyspnea Profile result questionnaire | 21 days | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Inspiratory muscle training, COPD, Conventional respiratory rehabilitation, Dyspnea scale
Anesthesia for Ambulatory Pediatric Surgery in Sub-Saharan Africa (SSA)

Study Overview
=================
Brief Summary
-----------------
Long surgical wait-times and limited hospital capacity are common obstacles to surgical care in many countries in sub-Saharan Africa (SSA). Ambulatory surgery might offer a solution to these problems. The aim is to study the introduction of ambulatory surgery in a pediatric hospital in SSA. This is a cross-sectional descriptive study which took place over 6 months. It includes all the patients assigned to ambulatory surgery in the Pediatric University Hospital in Ouagadougou, Burkina Faso.

Official Title
-----------------
Anesthesia for Ambulatory Pediatric Surgery in Sub-Saharan Africa (SSA): a Pilot Study in Burkina Faso

Conditions
-----------------
Complications

Intervention / Treatment
-----------------
* Procedure: Anesthesia for ambulatory paediatric surgery


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: ASA 1 status elective surgery with low potential for blood loss or severe pain, lasting less than 90 minutes whose parents could be contacted by telephone and who could return to the hospital in less than 1 hour Parents gave consent for the surgical procedure Exclusion Criteria: non operative patients

Ages Eligible for Study
-----------------
Minimum Age: 1 Year
Maximum Age: 15 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: children undergoing ambulatory surgery<br> | Procedure: Anesthesia for ambulatory paediatric surgery<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Failure of ambulatory surgery | number of patients that have been hospitalized (for whom ambulatory have been conversed to hospitalization) | 1day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Morbidity | Number of patients that presented complications of anesthesia or surgery such as nausea, vomiting, drowsiness and fever. | 3 days | 
| Complication after discharge from hospital | number of phone calls from parents of patients after ambulatory discharge | 3 days |
Quality of Life (QOL) Following Parathyroid Surgery

Study Overview
=================
Brief Summary
-----------------
The only established treatment for the complete resolution of hyperparathyroidism is the surgical removal of the affected glands. While proven as a means of resolving hyperparathyroidism, there have been no comprehensive preoperative and postoperative assessments to determine quality of life for patients undergoing minimally invasive vs. traditional parathyroid surgery. Quality of life will be assessed in subjects undergoing minimally invasive procedures and traditional procedures using a clinically validated survey. We will gather data one week preoperatively as well as one week and one year postoperatively then compare the survey results from the two study groups to each other. We will also compare the study groups to a control group consisting of patients undergoing thyroid surgery. Our ultimate goal is to clarify if minimally invasive parathyroid surgery techniques contribute to a higher patient quality of life as compared to traditional techniques.

Official Title
-----------------
Does Quality of Life Improve Following Minimally Invasive Parathyroid Surgery?

Conditions
-----------------
Parathyroidectomy

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: parathyroidectomy Exclusion Criteria: subjects under the age of 18

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
A Russian Prospective Observational Study of Invasive Fungal Infections in Patients With Acute Leukemia and Hematopoietic Stem Cell Transplantation

Study Overview
=================
Brief Summary
-----------------
Estimate the rate of occurrence of Invasive Fungal Infections (IFIs) in patients with acute leukemia for the first 6 months of chemotherapy (that usually correspond to four courses of chemotherapy), and hematopoietic stem cells transplantation.

Detailed Description
-----------------
This multi-center observational study of IFI in high risk hematological patients, the study will investigate the epidemiology of IFI, describe antifungal strategy, proportion of antifungal prophylaxis, empiric therapy, pre-emptive therapy and targeted therapy in at-risk patients.

Official Title
-----------------
A Russian Prospective Observational Study of Invasive Fungal Infections in Patients With Acute Leukemia and Hematopoietic Stem Cell Transplantation

Conditions
-----------------
Invasive Fungal Infections

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Diagnosed with de novo or relapsed AL (AML, ALL)started chemotherapy All newly allogeneic or autologous transplant recipients during the study period

Ages Eligible for Study
-----------------
Minimum Age: 1 Year
Maximum Age: 95 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Acute leukemia patients<br>Patients with de novo or relapsed acute myeloid and lymphoid leukemia | |
| Allo- or auto- transplant recipients<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The Rate of Invasive Fungal Infections | Estimate the rate of IFIs in patients with acute leukemia for the first 6 months of chemotherapy (that usually correspond to four courses of chemotherapy), and hematopoietic stem cells transplantation. | 6 month | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Invasive fungal infection, Acute leukemia (AL), Hematopoietic stem cell transplantation, Antifungal stewardship, Neutropenia, Hematological malignancies