Effects of Electromagnetic Therapy Versus Laser Therapy on Peripheral Diabetic Neuropathy

Study Overview
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Brief Summary
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This study are to: Evaluate effect of magnetic therapy on peripheral neuropathy in diabetic patients. Evaluate effect of laser therapy on peripheral neuropathy in diabetic patients. Compare effects of magnetic therapy with that of laser therapy on peripheral neuropathy in diabetic patients.

Detailed Description
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Sixty- five male and female diabetic patients with peripheral neuropathy will be selected to participate in this study. They will be equally divided into two groups Group-I: Twenty five patient with diabetic peripheral neuropathy will be exposed to low intensity pulsed magnetic therapy Group-II: Twenty five patients with diabetic peripheral neuropathy will be exposed for 24 treatment sessions of laser therapy Group-III 15 patient received only medical treatment

Official Title
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Effects of Electromagnetic Therapy Versus Laser Therapy on Peripheral Neuropathy in Diabetic Patients

Conditions
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Diabetes

Intervention / Treatment
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* Device: Magnetic therapy
* Device: laser therapy
* Drug: Only medical treatment


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All diabetic patients with peripheral neuropathy will be selected to participate in this study. Their age ranges from 35 to 65 years old. All patients under medical control (optimal blood glucose). such as analgesic medications (e.g. opiates, anti-depressants, anticonvulsants and diabetic drugs to control blood glucose). Exclusion Criteria: Patients have DPN due to other causes than diabetes Ulcers in either foot Lack of blood sugar control Other nervous system impairments Visual problems Unstable medical conditions Pregnancy Metallic implants Alcohol or drug abuse.

Ages Eligible for Study
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Minimum Age: 35 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Magnetic Therapy<br>Twenty five patient were exposed to low intensity pulsed magnetic therapy with a frequency of 200 Hertz and intensity of 50 Gauss for 30 minutes / session for 2 times per week for 3 months . | Device: Magnetic therapy<br>* low intensity pulsed magnetic therapy with a frequency of 200 Hertz and intensity of 50 Gauss . Magnetic device will be applied on each patient from a comfortable supine lying position. After the connection of appliance to electrical supply, the actions of PEMF will be directed and adjusted over lumbar spine, hip regions and calf muscles of both lower limbs.<br>|
| Experimental: Laser Therapy<br>Twenty five patients were treated with 24 sessions of laser therapy at a rate of two sessions / week for three months. Each patient will be exposed to Helium neon infrared laser (850 nano-meter continuous wave mode from a comfortable prone lying position. | Device: laser therapy<br>* laser therapy of Helium neon infrared laser (850 nano-meter) was used in continuous wave mode from a comfortable prone lying position on the whole plantar surface of the foot and the lumbo-sacral area by four points, and two points laterally to the spine.<br>|
| Experimental: Medical therapy<br>Fifteen patients were received only medical treatment . | Drug: Only medical treatment<br>* Fifteen patients with diabetic peripheral neuropathy were treated with antidiabtic drugs and lyrica 150 milligram daily<br>* Other names: Lyrica 150 milligram;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Motor and sensory conduction velocity of the lower limb nerves | it is used for measuring motor and sensory conduction velocity: For this purpose nerve conduction studies (NCSs) will be performed for all patients including evaluation of bilateral peroneal and tibia motor nerves and sural sensory nerves (Asad 2009). Patients with NCV from 33-48m /sec will be recruited in this study (Pericz and Cvetkovic 2006 , and Graak 2009). All measurement will be done at stander room temperature of 25 c. The skin temperature of the leg was maintained at 37ᴄ. (Asad et al 2009). | 30-45 minutes | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Neuropathies laser and magnetic therapy