linjc16/ctgov huggingface dataset:
Use of Medicinal Plants and Other Alternative and Complementary Medicines by Patients With Cancer in Reunion Island

Study Overview
=================
Brief Summary
-----------------
Exploratory, observational and cross-sectional study with the aim of describing the use of plants for medicinal purposes (and other Complementary and Alternative Medicine) and identifying the determinants of this use. The methodology envisaged is mixed with an exploratory design combining qualitative (interviews) and quantitative techniques (questionnaires). To knowledge of investigators, no study has been carried out in Reunion Island on the use of plants and other alternative and complementary medicines among cancer patients.

Official Title
-----------------
Evaluation of the Use of Medicinal Plants and Other Alternative and Complementary Medicines by Patients With Cancer in Reunion Island

Conditions
-----------------
Cancer

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Living in Reunion Island Suffering from cancer (solid tumors, hematological malignancies) Able to answer a questionnaire Patient who does not oppose to the research Exclusion Criteria: Person of legal age under guardianship or under legal protection Persons who do not understand French or Reunionese Creole

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Qualitative group<br>Interview about the use of Complementary and Alternative Medecine | |
| Quantitative group<br>Questionnaire about the use of Complementary and Alternative Medecine | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Use of herbal medicine | Proportion of patients using herbal medicine (from the patient's perspective) among cancer patients. | Day 1 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Barriers of dialogue between patient and practionner | Interviews between patient and interviewer will help to extract the barriers limiting patient/practitioner dialogue on Complementary and Alternative Medicine use from patient and practitioner perspectives | Day 1 | 
| Need for Information on Complementary and Alternative Medicine | Interviews between patient and interviewer will help to find out expectations about the need for information on Complementary and Alternative Medicine use from the patient's perspective and from the practitioner's perspective | Day 1 | 
| Improving questionnaire after the practionners' focus group | A practionners' focus group will be organised after the interviews to review the feedbacks and opinions on the questionnaire to improve the questionnaire for the quantitative part of the study | Day 1 |
Local Intraoperative Analgesic Injection Versus Single Injection Interscalene Nerve Block in Patients Undergoing TSA

Study Overview
=================
Brief Summary
-----------------
A non-blinded randomized controlled trial, in which participants undergoing primary reverse or total shoulder arthroplasty are randomly assigned to one of two treatment groups.

Official Title
-----------------
Local Intraoperative Analgesic Injection Versus Single Injection Interscalene Nerve Block in Patients Undergoing Shoulder Arthroplasty (TSA): A Randomized Trial

Conditions
-----------------
Osteoarthritis: Shoulder

Intervention / Treatment
-----------------
* Procedure: Interscalene brachial plexus block
* Procedure: bupivacaine extended-release liposome injection


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 1. All individuals undergoing primary reverse and total shoulder arthroplasty by the shoulder service at Methodist Hospital or Rothman Specialty Hospital. Exclusion Criteria: Psychiatric illness as defined by co-morbid diagnosis of bipolar disorder or schizophrenia Revision arthroplasty, arthroplasty for fracture Unable/unwilling to consent for enrollment Unable to complete postoperative pain survey Known adverse drug reaction or allergy to the medications used Chronic pain syndromes (including reflex sympathetic dystrophy, fibromyalgia, chronic diffuse musculoskeletal pain) Patients taking long acting narcotic pain medications (including extended release narcotic pain medications and methadone). Patients under the age of 18 years Patients with history of hepatic disease Pregnant women or women who are breastfeeding

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: interscalene brachial plexus block<br>Direct interscalene nerve block injection via brachial plexus | Procedure: Interscalene brachial plexus block<br> <br> |
| Active Comparator: Bupivacaine extended-release liposome injection<br>Infiltration of local anesthetic/analgesic, Bupivacaine extended-release liposome injection (Exparel) + Diluted in 40cc of Saline into the capsule, subscapularis, deltoid, pectoralis major and subcutaneous tissues. | Procedure: bupivacaine extended-release liposome injection<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Morphine and Morphine Equivalent consumption |  | 24 hours following surgery |
Oral Dydrogesterone in the Management of Preterm Labor

Study Overview
=================
Brief Summary
-----------------
This study evaluates the addition of oral dydrogesterone to standard treatment in the treatment of preterm labor. Half of participants will receive oral dydrogesterone and standard treatment, while the other half will receive oral placebo and standard treatment.

Official Title
-----------------
Oral Dydrogesterone as Adjunctive Therapy in the Management of Preterm Labor: A Randomized, Double Blinded, Placebo-controlled Trial

Conditions
-----------------
Preterm Labor

Intervention / Treatment
-----------------
* Drug: Dydrogesterone
* Drug: placebo


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: singleton pregnancy with gestational age 24-33 weeks 6 days preterm labor received treatment with tocolysis and corticosteroids Exclusion Criteria: conditions that need immediate delivery such as fetal distress, chorioamnionitis have medical complications such as heart disease, seizure fetal anomalies cervical dilatation more than 5 cm allergy to dydrogesterone

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Dydrogesterone<br>dydrogesterone 10 mg by mouth every 8 hours until delivery | Drug: Dydrogesterone<br>* dydrogesterone capsule<br>|
| Placebo Comparator: Placebo<br>placebo by mouth every 8 hours until delivery | Drug: placebo<br>* placebo capsule<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| latency period | time from preterm labor to delivery | 13 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| preterm delivery less than 34 weeks | percentage of delivery less than 34 weeks | 10 weeks | 
| preterm delivery less than 37 weeks | percentage of delivery less than 37 weeks | 13 weeks | 
| neonatal complications | percentage of newborn with RDS, IVH, NEC, death | 13 weeks | 
| side effects | percentage of side effects such as headache, nausea/vomiting | 13 weeks | 
| compliance | percentage of complete drug use | 13 weeks | 
| satisfaction | percentage of good satisfaction | 13 weeks | 
| Time to the recurrence of uterine contractions | Time to the recurrence of uterine contractions | 13 weeks |
Using Focus Group to Explore Cultural Acceptability of Contraception

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to learn what women of childbearing age think of Long Acting Reversible Contraception. A variety of myths regarding LARCs have been described in the literature. This study is designed to asses women's cultural belief's regarding LARCs. Investigators are looking to collect information from women in general, rather than solely who are seeking contraception. Investigators will be recruiting women ages 18-45 years from seven family health centers affiliated with UPMC. Participants will be asked to a attend a 60-90 minutes focus group session. During the session the facilitator will try to engage participants in a discussion about contraception in general. They will also be asked to complete a short demographic survey of 8-12 questions. Data from focus groups will be assessed for recurring themes which will be used to create a cultural survey instrument that will be used in the second phase of the study.

Detailed Description
-----------------
Following approval by the University of Pittsburgh institutional review board (IRB), female participants between 18 and 45 years of age seeking care for contraception or other women's health services were recruited from seven Family Health Centers (FHCs) partnered with the Department of Family Medicine. The participants agreed to participate in one 2 hour facilitated focus group session (recorded for later transcription) to discuss their perceptions about contraception. Recordings were transcribed and de-identified. The resulting texts were coded by a team. Concepts and themes that arose from the coding were analyzed to inform the development of a survey on the topic of perspectives on contraception. Qualitative analysis of the transcripts and coding was carried out and results were shared in pubic fora.

Official Title
-----------------
Using Focus Group to Explore Cultural Acceptability of Long Acting Contraception in a Diverse, Urban Population.

Conditions
-----------------
Contraception

Intervention / Treatment
-----------------
* Behavioral: Focus Group


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Female Age 18-45 years Not pregnant Exclusion Criteria: Pregnancy Male

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: Focus Group|We had recruited 64 women and completed 7 focus group sessions|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Level of acceptance of contraception among diverse women | Level of acceptance: 1-Totally not accepted 2-May accept 3-Neither accept/not accept 4-Accept with preservation 5-Totally accept | Three months |
Pseudophakic Accommodation

Study Overview
=================
Brief Summary
-----------------
Purpose: The aim of this study was to compare the effect of ciliary body training as proposed by manufacturers of accommodating IOLs and patient motivation on the pseudoaccommodative ability with a standard intraocular lens (SA60AT). Setting: Department of Ophthalmology, Medical University of Vienna. Methods: This randomized, controlled, examiner-masked study comprised 80 eyes of 40 patients that underwent standard cataract surgery. Patients were randomly assigned to a motivated or non-motivated (control) group. In the motivated group, subjects were told to take part in a special protocol to improve their near-reading ability after cataract surgery and were instructed not to use near adds for at least 3 months. Follow-up examinations included best-corrected distance visual acuity (VA), distance-corrected near VA, best-corrected near VA, defocus curve and reading speed, as well as pilocarpine-, cyclopentolate- and nearpoint-induced IOL shift assessed with partial coherence interferometry.

Conditions
-----------------
Cataract

Intervention / Treatment
-----------------
* Behavioral: motivation


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients suffering from age-related cataract who are enrolled for cataract surgery. Age 50 to 75 years < 1 D of corneal astigmatism, estimated postoperative VA of 20/30 or better and IOL power between 16 and 27 dpt Exclusion Criteria: Patients with complications during cataract surgery or during the postoperative period, significant other ophthalmic diseases such as glaucoma, diabetic retinopathy, etc., or ophthalmic surgery other than cataract surgery

Ages Eligible for Study
-----------------
Minimum Age: 50 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: 1<br>motivated | Behavioral: motivation<br> <br> |
| No Intervention: 2<br>control | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| visual acuity (best-corrected distance VA, distance-corrected near VA, best-corrected near VA) |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| IOL shift (pilocarpine-, cyclopentolate- and nearpoint-induced) assessed with partial coherence interferometry |  |  | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
pseudophakic accommodation
Atlantis Symbicort

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to determine whether Symbicort compared with Advair, will be more effective in controlling asthma in adults and adolescents.

Official Title
-----------------
A Two Stage Randomized, Open-Label, Parallel Group, Phase III, Multicenter, 7 Month Study to Assess the Efficacy & Safety of SYMBICORT pMDI Adminstered Either as Fixed or as an Adjustable Regimen Versus a Fixed Regimen of Advair in Subjects 12 Yrs of Age and Older With Asthma.

Conditions
-----------------
Asthma

Intervention / Treatment
-----------------
* Drug: budesonide/formoterol (Symbicort)
* Drug: fluticasone/salmeterol (Advair)


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Diagnosis of asthma Baseline lung function tests as determined by protocol Required and received treatment with inhaled corticosteroids within timeframe and doses specified in protocol Exclusion Criteria: Has required treatment with any non-inhaled corticosteroid within previous 30 days, sensitivity to drugs specified in the protocol, or requires treatment with a beta-blockers Had cancer within previous 5 years or currently has any other significant disease or disorder as judged by the investigator

Ages Eligible for Study
-----------------
Minimum Age: 12 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 1<br>budesonide/formoterol | Drug: budesonide/formoterol (Symbicort)<br> <br> * Other names: Symbicort;|
| Active Comparator: 2<br>fluticasone/salmeterol | Drug: fluticasone/salmeterol (Advair)<br> <br> * Other names: Advair;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Asthma control assessed by asthma exacerbations |  | Continuosly throughout the treatment period | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Efficacy of Symbicort compared with Advair as assessed by use of rescue medication, asthma symptoms, lung function tests, quality of life reports, patient reported asthma control and patient satisfaction of Symbicort. |  | Daily and at 1, 3 and 6 months after start of treatmen | 
| Use of medical resources and medication for the treatment of asthma. |  | Throughout the treatment period | 
| Investigate safety profile of Symbicort compared to Advair |  | 1, 3 and 6 months after start of treatment and 1 week after end of tretment | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Asthma, inhaled cortocisteroids, Symbicort, budesonide/formoterol, Advair, fluticasone/salmeterol
Intervention Toward Truth-Telling and Advanced Directives in the Patient With Advanced or Metastatic Disease

Study Overview
=================
Brief Summary
-----------------
Family usually had a lot of burden to tell the truth to patients. The purpose of this study is to assess the effect of education materials and family conference for advanced cancer patients and family.

Official Title
-----------------
A Longitudinal Study That Assessed the Effectiveness of Intervention Toward

Conditions
-----------------
Advanced Cancer, Metastatic Cancer

Intervention / Treatment
-----------------
* Behavioral: family conference


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: advanced or metastatic cancer patients more than 20 years old clear consciousness and be able to communicate Exclusion Criteria: refuse to know the statement of himself/herself disease

Ages Eligible for Study
-----------------
Minimum Age: 20 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Health Services Research
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 1<br>Family conference + education materials | Behavioral: family conference<br>* family conference<br>|
| No Intervention: 2<br>education materials | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Questionnaires |  | before and 1 week after the intervention |
Validation of the French Version of the Back Belief Questionnaire

Study Overview
=================
Brief Summary
-----------------
The goal of this study is to carry out a transcultural validation of the Back Belief Questionnaire in order to assess its appropriateness for French-speaking populations.

Official Title
-----------------
Validation of the French Version of the Back Belief Questionnaire

Conditions
-----------------
Back Pain Lower Back Chronic

Intervention / Treatment
-----------------
* Other: Questionnaires


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: The patient must have given his/her informed and signed consent The patient must be insured or beneficiary of a health insurance plan The patient has had back pain for at least 3 months Exclusion Criteria: The patient is in an exclusion period determined by a previous study The patient is under judicial protection, under tutorship or curatorship The patient refuses to sign the consent It is impossible to correctly inform the patient The patient is pregnant The patient is breastfeeding

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Chronic back pain patients<br>Patients who have had back pain for at least three months. | Other: Questionnaires<br>* Each patient is asked to fill out several questionnaires: a french version of the BBQ, as well as the FABQ, the TAMPA score, and the Québec questionnaire, the Dallas score, the HAD score and a visual analog scale for pain.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in French BBQ questionnaire score | The change in the BBQ score subsequent to physical therapy will be evaluated. | after physical theraphy (3 months) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in FABQ score | The change in the FABQ questionnaire score following physical therapy will be evaluated. | post physical therapy (3 months) | 
| Change in TAMPA score | The change in the TAMPA score following physical therapy will be evaluated. | post physical therapy (3 months) | 
| Change in Québec questionnaire score | The change in the Québec questionnaire score following physical therapy will be evaluated. | post physical therapy (3 months) | 
| Change in DALLAS questionnaire score | The change in the DALLAS questionnaire score following physical therapy will be evaluated. | post physical therapy (3 months) | 
| Change in HAD questionnaire score | The change in the HAD questionnaire score following physical therapy will be evaluated. | post physical therapy (3 months) |