Infection Among Patients Undergoing Radical Cystectomy.

Study Overview
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Brief Summary
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Investigators plan to perform a review of medical records a single urology department to identify patients with febrile perioperative infection who underwent radical cystectomy and urinary diversion for bladder cancer from January 2014 to July 2017. Investigators plan assess a potential variables to find correlation with infections after surgery. Characteristics, including age, sex, length of hospital stay, body mass index (BMI), diabetes, hypertension, estimated glomerular filtration rate (eGFR), preoperative hydronephrosis, smoking status, neoadjuvant chemotherapy, pathological stage, lymph node involvement, types of urinary diversion, operative method (open/laparoscopic), operative time and receipt of a perioperative blood transfusion (PBT) will be asses as potential risk factor for perioperative infection.

Official Title
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Incidence of and Risk Factors for Perioperative Infection Among Patients Undergoing Radical Cystectomy

Conditions
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Cystostomy Infection

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients who underwent radical cystectomy and urinary diversion for bladder cancer. Exclusion Criteria: documented infection at the time of radical cystectomy concurrent organ resection such as nephrectomy, nephroureterectomy partial cystectomy
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients without documented infection.<br>Patients without infection during 30 day follow-up after radical cystectomy. | |
| Patients with documented infection.<br>Patients with documented any kind of infection (urinary tract infection, blood infection/septic shock, surgical site infection) during 30 day follow-up after radical cystectomy. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of participants with perioperative infection after radical cystectomy. | A review of medical records in a single urology department will be performed to identified all participants with perioperative infection after radical cystectomy. | 30 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Association between perioperative infection after radical cystectomy and patients' age. | Logistic regression analysis. | 30 days | 
| Association between perioperative infection after radical cystectomy and sex. | Logistic regression analysis. | 30 days | 
| Association between perioperative infection after radical cystectomy and length of hospital stay. | Logistic regression analysis. | 30 days | 
| Association between perioperative infection after radical cystectomy and body mass index. | Logistic regression analysis. | 30 days | 
| Association between perioperative infection after radical cystectomy and diabetes. | Logistic regression analysis. | 30 days | 
| Association between perioperative infection after radical cystectomy and hypertension. | Logistic regression analysis. | 30 days | 
| Association between perioperative infection after radical cystectomy and estimated glomerular filtration rate | Logistic regression analysis. | 30 days | 
| Association between perioperative infection after radical cystectomy and preoperative hydronephrosis. | Logistic regression analysis. | 30 days | 
| Association between perioperative infection after radical cystectomy and smoking status. | Logistic regression analysis. | 30 days | 
| Association between perioperative infection after radical cystectomy and neoadjuvant chemotherapy. | Logistic regression analysis. | 30 days | 
| Association between perioperative infection after radical cystectomy and pathological stage. | Logistic regression analysis. | 30 days | 
| Association between perioperative infection after radical cystectomy and lymph node involvement. | Logistic regression analysis. | 30 days | 
| Association between perioperative infection after radical cystectomy and types of urinary diversion. | Logistic regression analysis. | 30 days | 
| Association between perioperative infection after radical cystectomy and operative method (open/laparoscopic). | Logistic regression analysis. | 30 days | 
| Association between perioperative infection after radical cystectomy and operative time. | Logistic regression analysis. | 30 days | 
| Association between perioperative infection after radical cystectomy and receipt of a perioperative blood transfusion. | Logistic regression analysis. | 30 days |