Epidemiology of Severe Peroperative Bleeding During Scheduled Surgery

Study Overview
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Brief Summary
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Peroperative bleeding has been studied in specific populations exposed to bleeding (i.e. cardiac surgery, orthopedic surgery). Epidemiology of peroperative bleeding and transfusion remain poorly studied in the whole cohort of patients scheduled for surgery remain unknown. The investigators conducted a prospective study in order to examine the incidence, and risk factors associated with peroperative bleeding and transfusion.

Detailed Description
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This was a prospective observational including all consecutive patients scheduled for surgery during a 3 month period. Exclusion criteria were : emergency, cardiac surgery, and pediatric surgery. Patients received an oral information and informed consent was search for all of them. Throughout the study period (3 months) data were prospectively recorded by members of a specific research team not involved in the care of patients. Preoperative, peroperative and immediate postoperative data (post anesthesia care unit) were collected. Unanticipated bleeding was defined as either transfusion above the pre ordered packed red blood cells or hemoglobin concentration < 8 g/dL.

Official Title
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Epidemiology of Peroperative Bleeding and Transfusion During Scheduled Surgery.

Conditions
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Surgery, Blood Loss

Intervention / Treatment
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* Other: Control
* Other: Unanticipated bleeding


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patient scheduled for non cardiac and non emergency surgery Exclusion Criteria: Cardiac surgery Emergency surgery

Ages Eligible for Study
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Minimum Age: 16 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| control<br>Patients with either transfusion with pre ordered packed red blood cells or hemoglobin concentration > 8 g/dL. | Other: Control<br>* Control patients were defined as either transfusion using only pre ordered packed red blood cells or peroperative hemoglobin concentration >8 g/dL.<br>|
| unanticipated bleeding<br>Unanticipated bleeding was defined as either transfusion above the pre ordered packed red blood cells or hemoglobin concentration < 8 g/dL. | Other: Unanticipated bleeding<br>* Unanticipated bleeding was defined as either transfusion above the pre ordered packed red blood cells or peroperative hemoglobin concentration < 8 g/dL.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Unanticipated Bleeding | From arrival in operating room until the patients leave post anesthesia care unit | one day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Transfusions | transfusion pattern in the whole cohort | one day | 
| Preoperative Anemia | proportion of patients with preoperative anemia | one day | 
| Lowest Hemoglobin | lowest peroperative hemoglobin concentration | one day |