Understanding Public Attitudes Towards the COVID-19 Vaccination

Study Overview
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Brief Summary
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The objective of this study is to better understand public attitudes towards coronavirus disease 2019 (COVID-19) vaccination. This understanding will inform the development of community engagement strategies to be used in future interventions and studies aimed at addressing factors that impact the disproportionate burden of COVID-19 in under-served and vulnerable communities.

Detailed Description
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The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly instigated a global pandemic. As of this writing, there are more than 33 million documented cases of infection in the United States (US). Furthermore, in the US, COVID-19 has disrupted the economy, overwhelmed the healthcare system, led to widespread school cancellations, and caused more than 595,000 deaths since March 2020. The availability of three highly effective vaccines against COVID-19 within a year of the start of the pandemic is an extraordinary achievement and cause for great optimism. However, a significant proportion of adults in the U.S. have not accepted vaccination against COVID-19. Efforts are needed to identify effective messages and communication strategies to overcome COVID-19 vaccine hesitancy. To address this need, the investigators plan to conduct two rapid surveys among Massachusetts residents, to assess attitudes towards COVID-19 vaccination.

Official Title
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Together Researching Understanding, Solidarity, and Trust Around COVID - TRUST Study

Conditions
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Covid19, Vaccination

Intervention / Treatment
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* Behavioral: Communication about the COVID-19 vaccination from the Massachusetts Department of Public Health


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Massachusetts resident Adult (age 18 and over) English or Spanish speaking Exclusion Criteria: • Non-English or Spanish speaking

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Message 1<br>Participants will be randomized to receive version #1 of 2 different versions of a message from the Massachusetts Department of Public Health regarding the COVID-19 vaccination. | Behavioral: Communication about the COVID-19 vaccination from the Massachusetts Department of Public Health<br>* Participants will be randomized to receive one of two different versions of messages from the Massachusetts Department of Public Health. The message that participants in each experimental group receive will vary slightly and systematically. Specific content and wording of these messages were developed to address and mitigate concerns about the Covid-19 vaccination.<br>|
| Experimental: Message 2<br>Participants will be randomized to receive version #2 of 2 different versions of a message from the Massachusetts Department of Public Health regarding the COVID-19 vaccination. | Behavioral: Communication about the COVID-19 vaccination from the Massachusetts Department of Public Health<br>* Participants will be randomized to receive one of two different versions of messages from the Massachusetts Department of Public Health. The message that participants in each experimental group receive will vary slightly and systematically. Specific content and wording of these messages were developed to address and mitigate concerns about the Covid-19 vaccination.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Intent to be vaccinated against Covid-19 among unvaccinated participants | The survey includes a question that assesses participants' willingness to be vaccinated against Covid-19 if they are unvaccinated. Responses include Yes, No, or Not Sure to being vaccinated against Covid-19. | Through survey completion, an average of 12 minutes |