Laparoscopic Eradication of Deep Endometriosis With Nerve-sparing Rectosigmoid Segmental Resection (RSRES_NERVSP)

Study Overview
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Brief Summary
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This is a single-center, retrospective case-control study. All consecutive women who underwent classic and nerve-sparing segmental rectosigmoid resection between January 2005 and June 2022 will be included. In the majority of cases classic segmental rectosigmoid resection was done between January 2005 and December 2010. Nerve-sparing segmental rectosigmoid resection has been increasingly employed since January 2011 until now. Preoperative (anamnestic, physical objective, and ultrasonographic data), surgical and postoperative data of the patients included in this study will be analyzed. In particular, postoperative data will be obtained by analyzing reports of follow-up visits, which are routinely done at our institution at 1, 6, 12 months and then every year following the surgical procedures.

Official Title
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Laparoscopic Eradication of Deep Endometriosis With Nerve-sparing Rectosigmoid Segmental Resection: a Comparative Retrospective Analysis (RSRES_NERVSP)

Conditions
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Endometriosis

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: consecutive women who underwent classic and nerve-sparing segmental rectosigmoid resection between January 2005 and June 2022 age more than 18 years. Exclusion Criteria: diagnosis of other/concomitant preoperative and/or postoperative medical or surgical conditions altering pelvic organ function (i.e. multiple sclerosis, irritable bowel syndrome); age <18 years.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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Female

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of patients having intraoperative complications | Number of patients having intraoperative complications evaluated by surgical data stored in the hospital medical electronic register | During the surgical procedures | 
| Number of patients having short-term postoperative complications | Number of patients having short-term postoperative complications evaluated by clinical data stored in the hospital medical electronic register at the follow-up visits | 3 months after the surgical procedures | 
| Number of patients having middle-term postoperative complications | Number of patients having short-term postoperative complications evaluated by clinical data stored in the hospital medical electronic register at the follow-up visits | 6 months after the surgical procedures | 
| Number of patients having long-term postoperative complications | Number of patients having short-term postoperative complications evaluated by clinical data stored in the hospital medical electronic register at the follow-up visits | 12 months after the surgical procedures | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Intraoperative blood loss (ml) | Intraoperative blood loss (ml) evaluated by surgical data stored in the hospital medical electronic register | During the surgical procedures | 
| Number of patients having an intraoperative laparotomic conversion | Intraoperative blood loss (ml) evaluated by surgical data stored in the hospital medical electronic register | During the surgical procedures | 
| Operative time (min) | Operative time (min) evaluated by surgical data stored in the hospital medical electronic register | During the surgical procedures | 
| Number of patients undergoing a concomitant additional surgical procedure | Number of patients undergoing a concomitant additional surgical procedure evaluated by surgical data stored in the hospital medical electronic register | During the surgical procedures |