linjc16/ctgov huggingface dataset:
Virtual Management of Rheumatoid Arthritis

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to optimize the care of patients with RA seen in virtual consultation.

Detailed Description
-----------------
This study will be organized in two consecutive steps: A first descriptive step that will consist of a retrospective analysis of virtual consultation records of patients with RA during the pandemic and lockdown period in order to analyze on which criteria the patients were assessed and followed during this period. The second step will consist in evaluating the interest of the systematic use in virtual consultation of a patient reported outcome (PRO), the RAID (Rheumatoid Arthritis Impact of Disease) questionnaire; and analyze how its results influence the rheumatologist decision-making.

Official Title
-----------------
Evaluation of Rheumatoid Arthritis at the Time of Telemedicine

Conditions
-----------------
Rheumatoid Arthritis

Intervention / Treatment
-----------------
* Other: Rheumatoid Arthritis Impact of Disease questionnaire


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with rheumatoid arthritis fulfilling the 2010 ACR/EULAR classification criteria Follow-up in the rheumatology department of Cochin Hospital Affiliated with a social security scheme Non-opposition to participating in the study Patients with a valid email address (registration to the virtual consultation system) Exclusion Criteria: Opposition to participate to this research Inability to understand or speak French Patient under tutor or curator ship patients under medical state help
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients with rheumatoid arthritis<br>Patients seen in virtual consultation | Other: Rheumatoid Arthritis Impact of Disease questionnaire<br>* Rheumatoid Arthritis Impact of Disease questionnaire<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rate of face to face consultation, hospitalization and therapeutic modifications | The primary outcome will be the rate of face to face consultation, hospitalization and therapeutic modifications decided by the rheumatologist during the virtual consultation | Inclusion | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Rheumatoid arthritis, Virtual consultation, Telemedicine, Patient reported outcome
Left Ventricular and Endothelial Function in Preeclampsia

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is (1) to examine whether the left ventricular function is impaired in women with preeclampsia relative to healthy pregnant controls, (2) to examine whether the endothelial function is impaired in women with preeclampsia relative to healthy pregnant controls, and (3) to examine whether there is a post partum impairment in left ventricular and endothelial function.

Official Title
-----------------
Left Ventricular and Endothelial Function in Preeclampsia, a Case Control Study

Conditions
-----------------
Preeclampsia

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: >18 years of age Case: Clinical diagnosis of preeclampsia, Control: Systolic BP <140 mmHg and diastolic BP <90 mmHg Exclusion Criteria: Known hypertension or other cardiovascular disease Diabetes/gestational diabetes Multiple gestation

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 40 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| preeclampsia<br>women with preeclampsia | |
| controls<br>healthy pregnant women | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Left Ventricular Function |  | 3 months | 
| Endothelial Function |  | 3 months |
Local Versus General Anaesthesia in Stapled Hemorrhoidectomy

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to determine whether local or general anaesthesia in stapled hemorrhoidectomy leads to a shorter operation time with a better patient comfort.

Detailed Description
-----------------
Hemorrhoids are a frequent disease with the need of surgical intervention in 10-20% of the patients. The stapled hemorrhoidectomy according to Longo under general anesthesia (or spinal) is considered standard of care [1]. Cohort studies show that a pudendal bloc with local anesthesia is safe and efficient [2-4]. The majority of procedures are actually performed in private clinics or in an ambulatory setting underlining the importance of economic issues such as procedure time (anesthesia and operation time) and hospital stay. We hypothesize that stapled hemorrhoidectomy under local anaesthesia shortens anaesthesia time and hospital stay and reduces costs with no disadvantages regarding pain, satisfaction and complication rate.

Official Title
-----------------
Local vs General Anaesthesia in Stapled Hemorrhoidectomy: A Multicentric Controlled Randomized Trial

Conditions
-----------------
Hemorrhoids

Intervention / Treatment
-----------------
* Procedure: Local anesthesia (pudendal block)
* Procedure: general anesthesia (spinal and general)


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Hemorrhoids grade III suitable for elective stapled hemorrhoidectomy Exclusion Criteria: Age < 18 years No informed consent Emergency situation Contraindication to either anaesthesia method Patients not speaking french or german. Additional anal pathology (fissure, tumour).

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 90 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: A: general<br>general anesthesia: spinal and general | Procedure: general anesthesia (spinal and general)<br>* general according to guidelines<br>* Other names: general;|
| Experimental: B: pudendal<br>local anesthesia: pudendal block | Procedure: Local anesthesia (pudendal block)<br>* local anesthesia as indicated<br>* Other names: local;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
anesthesia, Longo, mucosectomy, hemorrhoids
A Clinical Study Comparing Superior Capsule Reconstruction Using Different Graft for Irreparable Rotator Cuff Tear

Study Overview
=================
Brief Summary
-----------------
Biomechanical and clinical success of the superior capsule reconstruction (SCR) using fascia lata (FL) grafts has been reported in treating irreparable rotator cuff tear. Human dermal (HD) allograft has been used successfully for SCRs; however, the clinical comparative study between FL and HD have not been reported.

Official Title
-----------------
A Clinical Study Comparing Superior Capsule Reconstruction Using Fascia Lata Allograft With Human Dermal Allograft for Irreparable Rotator Cuff Tear

Conditions
-----------------
Rotator Cuff Tears

Intervention / Treatment
-----------------
* Procedure: fascia lata allograft
* Procedure: human dermal allograft


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with irreparable rotator cuff tears Underwent superior capsule reconstruction using fascia lata allograft with human dermal allograft At least two years follow-up Exclusion Criteria: reparable rotator cuff tears underwent partial repair or reverse total shoulder arthroplasty
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Fascia lata group<br> | Procedure: fascia lata allograft<br>* underwent superior capsule reconstruction using fascia lata allograft<br>|
| Experimental: Dermal allograft group<br> | Procedure: human dermal allograft<br>* underwent superior capsule reconstruction using human dermal allograft<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| American Shoulder and Elbow Surgeons (ASES) score | A patient-reported outcome measurement | 2 year postoperatively | 
| Acromiohumeral distance (AHD) | measured in X-ray | 1 year postoperatively | 
| Retear rate | Measured in MRI | 1 year postoperatively | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Irreparable Rotator Cuff Tears, Superior Capsular Reconstruction, Fascia lata allograft, human dermal allograft
The Chest Physiotherapy and Breathing Exercises Management of Patients Following Open Heart Surgery: a National Survey of Practice in Turkey.

Study Overview
=================
Brief Summary
-----------------
Chest physiotherapy and breathing exercises are an important non-pharmacological treatment modality in order to prevent and minimize postoperative respiratory complications in patients undergoing open heart surgery. Different respiratory techniques are used after cardiac surgery, but there is no opinion about which technique or exercise is effective. The purpose of this study, practical application of chest physiotherapy to patients who have had open heart surgery in Turkey and to identify methods of breathing exercises.

Detailed Description
-----------------
In this study, cardiovascular surgery in Turkey to employees or physiotherapist who worked in intensive care units was planned as e-mail or by reaching to answer the survey questions via telephone. The universe of study in Turkey cardiovascular surgery physiotherapists are all actively working or have worked in intensive care.

Official Title
-----------------
The Chest Physiotherapy and Breathing Exercises Management of Patients Following Open Heart Surgery: a National Survey of Practice in Turkey.

Conditions
-----------------
Chest Physiotherapy

Intervention / Treatment
-----------------
* Other: Physiotherapists working in intensive care


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: To worked or still working in cardiovascular surgery intensive care units To answer the survey questions Exclusion Criteria: To Working or worked in cardiovascular surgery intensive care unit and but not answering questionnaire questions

Ages Eligible for Study
-----------------
Minimum Age: 25 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Physiotherapists working in intensive care|Physiotherapists working in intensive care will be reached by mail or telephone. Physiotherapists will be asked to complete the prepared questionnaire.|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Delivery of surveys | Questionnaire questions will be sent to physiotherapists via mail or telephone | 1 month | 
| Evaluation of survey results | Statistical evaluation and interpretation of survey results | 4 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
open cardiac surgery, breathing exercises, chest physiotherapy
The Real World Study of Apatinib for Gastric Cancer Treatment in Henan Province

Study Overview
=================
Brief Summary
-----------------
The investigators conduct the real world study to explore the efficacy and safety of Apatinib in gastric cancer .

Official Title
-----------------
The Real World Study of Apatinib for Gastric Cancer Treatment in Henan Province

Conditions
-----------------
Gastric Cancer

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Male or female patients . Confirmed by Pathology or histology of Gastric cancer. Patients should be voluntary to the trial and provide with signed informed consent. The researchers believe patients can benefit from the study. Exclusion Criteria: Patients with a known history of allergic reactions and/or hypersensitivity attributed to apatinib or its accessories. Pregnant or lactating women. Patients with Apatinib contraindications. Patients of doctors considered unsuitable for the trial.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Progress free survival |  | 1 year | 
| Disease-free surviva |  | 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| overall survival |  | 3 year | 
| Objective Response Rate |  | 1 year | 
| Disease Control Rate |  | 1 year |
Evaluation of Power Doppler US Technique for the Diagnosis of Spondylarthropathy

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to evaluate the interest of enthesis sonography for the diagnosis of spondylarthritis, in patients with uncertain diagnosis consulting for clinical symptoms suggestive of spondylarthritis

Detailed Description
-----------------
Spondylarthritis (SPA) are the second most frequent inflammatory rheumatic disorders and, because it starts early in life and has a chronic progressive course, the impact of this disease on health resources and patient's life quality can be important. Because the characteritic signs of SPA, like radiological evidence of sacro-iliitis, appear late in time, the lag time between the onset first signs of SPA for the patient and the confirmed diagnosis can be very long (up to 8 years). Previous studies proved that patients who are affected by SPA are showing abnormal vascularization of peripheral enthesis more frequently than patients affected by other rheumatic diseases. Ultrasonography in B mode combined with power Doppler (PDUS) is a non invasive and highly sensitive toll which can detect enthesitis and abnormal vsacularization even for the patients who are not showing yet the evidence of SPA's symptomatology. Using PDUS as a early diagnosis tool could lead to the improvement of diagnostic procedures and therapeutic management of SpA and reduce the cost of diagnosis for patient and health insurances.

Official Title
-----------------
Evaluation of Power Doppler US Technique for the Diagnosis of Spondylarthropathy in Patients With Uncertain Diagnosis Consulting for Clinical Symptoms Suggestive of Spondylarthropathy

Conditions
-----------------
Spondylarthropathy, Ankylosing Spondyloarthitis, Spondyloarthritis

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients < 50 years old, consulting for spinal inflammatory symptoms > 3 months duration patients consulting for arthritis or tenderness joints > 3 months duration patients < 50 years old consulting for enthesitis or dactylitis > 3 months duration patients with uveitis and HLA-B27 positivity relatives of SpA patients consulting for symptoms suggestive of SpA Exclusion Criteria: patient with confirmed diagnosis of rheumatic disease (included SpA) patient protected by law (patient <18 years old, pregnant woman) patient who can't atempt the RMI patient who will have difficulties to complete the two years of follow-up

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
National Cancer Institute Food Study

Study Overview
=================
Brief Summary
-----------------
Information about Americans food choices and opinions helps researchers and law makers to develop policies and programs to promote health. For this reason, it is important to be able to collect good quality information about how people think about food. This project will compare different ways of collecting information about food from adults.

Detailed Description
-----------------
Objectives: -To compare different ways of collecting information about food choices and opinions from adults. Eligibility: Individuals between the ages of 20 and 70, recruited from a database of volunteers who wish to participate in research studies. Volunteers must have high-speed Internet access. Individuals who have previously been involved in a research study will be excluded. Design: -Participants will come to a research study center for three consecutive meals (approximately 45 minutes per meal). On the following day, participants will return to the study center for an interview about their food choices and opinions (approximately 45 minutes).

Official Title
-----------------
National Cancer Institute (NCI) Food Study

Conditions
-----------------
Validation Study, Diet Surveys, Nutritional Assessment, Epidemiology, Methodologic Study

Participation Criteria
=================
Eligibility Criteria
-----------------
Eligibility Criteria Individuals between the ages of 20 and 70, recruited from a database of volunteers who wish to participate in research studies. Volunteers must have high-speed Internet access. Individuals who have previously been involved in a research study will be excluded. Subjects will be accrued from a variety of racial and ethnic groups and of varying educational achievement, though these characteristics will not be used to assess eligibility. All subjects will provide informed consent.

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Healthy volunteers<br>Healthy volunteers | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Agreement of truth and reported dietary intake | Measured exact intake of foods will be compared to reported intake by the participant. Two different reporting systems will be compared with truth. | 2 days | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Dietary Assessment Methods, Measurement of Diet, 24-Hour Diet Recall, Validation, Feeding Study
Assessment of the Immunization Levels Against Sars-Cov2 Virus in Subjects Who Have Received EU-approved COVID-19 Vaccines

Study Overview
=================
Brief Summary
-----------------
Patients who voluntarily visit vaccination centers in Greece against COVID-19 are recruited and their immunization levels against Sars-Cov2 are assesed by measurement of the levels of serum antibodies against Sars-cov-2 before vaccination and in time intervals up to 6-9 months post-vaccination (indicatively 0-1-3-6-9 months post-vaccination).

Official Title
-----------------
Assessment of the Immunization Levels Against Sars-Cov2 Virus in Subjects Who Have Received European Union (EU) -Approved COVID-19 Vaccines

Conditions
-----------------
SARS-CoV2 Infection, Vaccine Reaction

Intervention / Treatment
-----------------
* Biological: Approved vaccines against Sars-Cov2


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Subjects who voluntarily receive COVID-19 vaccination Exclusion Criteria: Patients who do not complete their vaccination Patients who do not provide info on their health status
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| VAC<br>Vaccinated subject against Sars-Cov2 | Biological: Approved vaccines against Sars-Cov2<br>* Subjects who voluntarily are vaccinated against Sars-Cov-2 with any of the approved vaccines by EU<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Antibody titer against Sars-Cov2 |  | 0-9 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
sars-cov2, vaccine, age