Study of a Cohort of Cases of Synovial Sarcoma Treated in the Orthopedic Surgery and Traumatology Department of the Hospital de Sant Pau Between 1983 and 2016

Study Overview
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Brief Summary
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The main objectives of this study are the following: to describe the prognostic factors of survival of synovial sarcoma in patients treated by the orthopedic surgery unit oncologic of the orthopedic surgery and traumatology service of the Hospital de Sant Pau during the years 1983-2016.

Detailed Description
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Another objectives of this Study are: To analyze exhaustively a series of cases of synovial sarcoma (as an example of classic subtype of soft tissue sarcoma) to analyse the complementary tests performed and their evolution over time. To analyse the results of surgical treatment and adjuvant therapies in synovial sarcoma and its evolution over time. To study the prognostic factors dependent on the patient and the applied therapeutics. To establish a results-based treatment and follow-up algorithm for patients diagnosed with synovial sarcoma. To describe the epidemiological characteristics of the group of patients in the study. To evaluate the overall survival and disease-free survival as well as the mortality of the disease. To assess the rate of local recurrence and remote dissemination of synovial sarcomas in the series. To demonstrate the influence of neoadjuvant chemotherapy and radiotherapy in the treatment of the tumor. Conduct a study by age group with respect to the influence on patient survival. To carry out a study by tumor-sized groups with respect to the influence on the survival of the patients. To carry out a chronological study on the influence of the advances in the treatments on the survival of the patients. Compare the results obtained with the published literature.

Official Title
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Observational, Descriptive and Retrospective Study of a Cohort of 90 Consecutive Cases of Synovial Sarcoma Treated in the Orthopedic Surgery Unit of the Orthopedic Surgery and Traumatology Department of the Hospital de Sant Pau Between the Years 1983 and 2016 ( 35 Years)

Conditions
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Soft Tissue Sarcoma Adult

Intervention / Treatment
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* Other: Soft tissue sarcomas in adults


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: The inclusion criteria were: diagnosed cases of synovial sarcoma by the service of pathological anatomy and treated by unit orthopedic surgery oncology, in location of limbs, paravertebral trunk and/or pelvis. We studied the complete medical history of the cases available for the analysis and with a minimum follow-up of 12 months. Exclusion Criteria:

Ages Eligible for Study
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Minimum Age: 10 Years
Maximum Age: 100 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Soft tissue sarcomas in adults|Adult sinovial sarcoma|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of cases of synovial sarcoma |  | Two years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Synovial sarcoma