Comparison of Early Phase Infections Risk Between Midline and Piccline Caheters: MIDLINE AND PICCLINE CATHETERS

Study Overview
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Brief Summary
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A long-term venous access is frequently required in patient management. Currently, it is ensured by using the long peripheral intravenous catheters (Midline) or peripheral inserted central catheters (PICC line). Either is inserted into a peripheral vein of the upper arm and extends to the distal axillary vein. If the indications for the two catheters can sometimes be debated, the Midline catheter seems to be more and more used. The complications related to the use of PICC lines have been well described in literature, whereas the comparison of the two catheter-related complications has been less analysed. The aim of this study is to compare the incidences of catheter-related bloodstream infections linked to PICCs and Midlines.

Detailed Description
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This single-center observational study will record and compare Midline and PICC line catheter-related bloodstream infections in the first 30 days after placement, catheter-related bloodstream infections being defined as clinical signs associated with a positive catheter culture (bacterial culture finding more than 103 CFU/mL) without any other infectious entry points. Catheter indications, insertion conditions, incidence of haemorrhagic and thrombotic complications during the first 30 days will be analyzed.

Official Title
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Comparison of Early Phase Infections Risk Between Midline and Piccline Caheters: MIDLINE AND PICCLINE CATHETERS

Conditions
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Catheter-related Bloodstream Infection

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Major ≥ 18 years old opposition formulated Exclusion Criteria: Refusal of participation Patients under legal protection (guardianship, curatorship, etc.)

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| PICCline group<br>Patients needing a vascular approach using PICCline catheters | |
| Midline group<br>Patients needing a vascular approach using Midline catheters | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Compared rate of catheter-related bloodstream infections in the first 30 days in Midline and PICCline group. Catheter-related bloodstream infections are defined as clinical signs with a positive catheter culture without any other infectious entry points. | catheter-related bloodstream infections being defined as clinical signs (fever, swelling, pain) associated with a positive catheter culture (bacterial culture finding more than 103 CFU/mL) without any other infectious entry points. the number of infections recorded will be compared between the group of patients having a Midline and the group of patients having a PICCline | first 30 days after placement | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| catheter placement time will be evaluated in days | catheter placement time will be evaluted by measuring the time between catheter placement and removal in days | first 30 days after placement | 
| rate of no infection complications like obstruction, accidental removal, thrombosis, hemorrhagic complications | The number of mechanical compliaction (obstruction, accidental removal, etc.), haemorrhagic and thrombotic complications recorded will be compared between the group of patients having a Midline and the group of patients having a PICCline | first 30 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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venous access, Midline, PICC line, catheter-related bloodstream infections