Prospective Registration Study of Robtic Laparoscopy Versus Laparoscopy Assisted Colon Cancer Surgery

Study Overview
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Brief Summary
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The purpose of this study is to compare the clinical data of patients with colon cancer who received robotic or laparoscopic surgery, and to compare the short-term and long-term effects of robotic surgery in the treatment of colon cancer. To verify the safety and effectiveness of the corresponding surgical methods, and provide better guidance for the following clinical practice.

Official Title
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Prospective Registration Study of Robtic Laparoscopy Versus Laparoscopy Assisted Colon Cancer Surgery

Conditions
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Da Vinci Robot, Colon Cancer, Surgery

Intervention / Treatment
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* Procedure: Da Vinci Robotic Surgery


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age: 18-80 years old, male or female; Colon cancer (ascending colon, transverse colon, descending colon, sigmoid colon) is diagnosed by histology or cytology; The clinical stage is T1-4aN0-2M0; 4 No multiple distant metastases; 5. ECOG score 0-2; 6. Heart, lung, liver, and kidney functions can tolerate surgery; 7. Patients and their families can understand and are willing to participate in this clinical study, and sign an informed consent. Exclusion Criteria: Past history of malignant colorectal tumors or recent diagnosis combined with other malignant tumors; Patients with intestinal obstruction, intestinal perforation, intestinal bleeding, etc. who need emergency surgery; Neighboring organs need to be combined with organ resection; New adjuvant therapy before surgery; ASA grade ≥ grade IV and/or ECOG physical status score> 2 points; Those who have severe liver and kidney function, cardiopulmonary function, blood coagulation dysfunction, or combined with serious underlying diseases that cannot tolerate surgery; Have a history of severe mental illness; Pregnant or lactating women; Patients with other clinical and laboratory conditions considered by the investigator should not participate in the trial.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Da Vinci Robotic Surgery Group<br>Da Vinci Robotic Surgery Group | Procedure: Da Vinci Robotic Surgery<br>* Da Vinci Robotic Surgery<br>|
| Laparoscopy-assisted surgery group<br>Laparoscopy-assisted surgery group | Procedure: Da Vinci Robotic Surgery<br>* Da Vinci Robotic Surgery<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of lymph nodes harvested | Number of lymph nodes harvested | During the operation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Operation time | Operation time | During the operation | 
| Length of surgical incision | Length of surgical incision | During the operation | 
| Intraoperative blood loss | Intraoperative blood loss | During the operation | 
| Intraoperative concversion rate | Intraoperative concversion rate | During the operation | 
| Postoperative recovery | first exhaust, defecation time, restoring liquid diet, hospitalization days, etc. | During the postoperative hospital stay | 
| 3-year disease-free survival | 3-year disease-free survival | 3 years after surgery | 
| 5-year overall survival | 5-year overall survival | 5 years after surgery |