Yoga Improves Aerobic Fitness, Glycemia and Mood State and Reduces Abdominal Obesity

Study Overview
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Brief Summary
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Stretching and flexibility exercise such as yoga and functional resistance exercise are two forms of exercise that are growing in popularity. However, they have not been scientifically tested to demonstrate their ability to improve body composition, fitness, heart and metabolic health, and mood state in overweight/obese women. The investigators hypothesize that during an 11 week intervention, both forms of exercise will improve body composition, heart and metabolic health and mood state.

Detailed Description
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This study was a 11 week protein-rich whole food diet and exercise training intervention in middle aged overweight/obese women. Subjects were randomized into 3 groups: Protein-rich whole food only consumed as 20-25 grams per serving 4-6 per day (P); protein and resistance exercise training (R); and protein and stretching/yoga exercise training (S). All outcomes, including the primary outcomes of body composition and cardiometabolic biomarkers were measured at baseline (week 0) and post-intervention (week 12) in all study subjects.

Official Title
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Yoga Improves Aerobic Fitness, Glycemia and Mood State and Reduces Abdominal Obesity in Overweight Women: The PRISE Study

Conditions
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Obesity, Insulin Resistance

Intervention / Treatment
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* Other: Protein whole foods
* Other: Protein Resistance Exercise Training
* Other: Protein Stretching/Yoga Training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: obese or overweight women between ages 25-60 and otherwise healthy Exclusion Criteria: smokers, habitual exercisers

Ages Eligible for Study
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Minimum Age: 25 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Protein whole foods<br>Ingestion of 20-25 grams per serving consumed 4-6 times per day; 1 within an hour of waking in the morning and the other 2.5-3 hours apart during the day. | Other: Protein whole foods<br>* Protein-rich whole foods consumed at 20-30 grams of protein at each of 4-6 meals per day<br>Other: Protein Resistance Exercise Training<br>* Protein rich whole foods diet and resistance training 3 times per week for 11 weeks<br>Other: Protein Stretching/Yoga Training<br>* Protein-rich whole foods diet of 20-30 grams of protein at each of 4-6 meals per day with stretching/yoga training 3 times per week for 11 weeks<br>|
| Experimental: Protein Resistance Exercise Training<br>Ingestion of 4-6 protein-rich meals per day and 3 times per week of resistance functional training. | Other: Protein whole foods<br>* Protein-rich whole foods consumed at 20-30 grams of protein at each of 4-6 meals per day<br>Other: Protein Resistance Exercise Training<br>* Protein rich whole foods diet and resistance training 3 times per week for 11 weeks<br>|
| Experimental: Protein Stretching/Yoga Training<br>Ingestion of Protein-rich diet 4-6 meals/day and stretching/yoga training 3 times per week | Other: Protein whole foods<br>* Protein-rich whole foods consumed at 20-30 grams of protein at each of 4-6 meals per day<br>Other: Protein Stretching/Yoga Training<br>* Protein-rich whole foods diet of 20-30 grams of protein at each of 4-6 meals per day with stretching/yoga training 3 times per week for 11 weeks<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Total and Regional Body Composition | Total and regional body composition was assessed by dual energy xray absorptiometry (DXA) at baseline and 11 weeks in all subjects | baseline and 11 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Aerobic Fitness | VO2 max was assessed in each subject at baseline and 11 weeks | baseline and 11 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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obesity, protein-rich whole foods diet, aerobic fitness, resistance training, stretching/yoga training, glycemia, mood state