App-based Cognitive Training at Home

Study Overview
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Brief Summary
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This randomized controlled trial is for investigating the effects of multidisciplinary intervention program on cognition and activity of daily living ability in community dwelling healthy elderly. The intervention consists of cognitive group training every month, daily home cognitive training using cognitive training smartphone application, record of weekly physical activity and body weight and feedback program, and alcohol and smoking cessation monitoring and feedback program. Among these interventions, app-based cognitive training at home is the major intervention in this study. The total duration of intervention is 1 year, and the tablet-based cognitive screening test and the patient-reported questionnaires to evaluate subjective memory decline, quality of life, depression, and activity of daily living are used for outcome measures.

Official Title
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Effects of App-based Cognitive Training on Cognition in Community Dwelling Elderly Using: A Randomized Controlled Trial

Conditions
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Healthy Volunteers, Aged

Intervention / Treatment
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* Behavioral: Multidisciplinary prevention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: literate education years >= 6 years not demented mini-mental status examination >= 24 android cellular phone users no significant decline in activities of daily living (Korea- Instrumental Activities of Daily Living =<5) Exclusion Criteria: Who has a history of major cardiovascular diseases within 3 months of study enrollment (ex. myocardial infarction, stroke) Who has current illnesses that could possibly affect cognition or with anticipated life expectancy of less than 2 years (ex. end stage cancer, on chemotherapy) Who has a severe hearing difficulty or visual disturbance Who has a limitation in communication Who was diagnosed with dementia Who has a plan for immigration or move in 1.5 years after study enrollment Who underwent a cognitive training within 6 months of study enrollment

Ages Eligible for Study
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Minimum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Intervention group<br> | Behavioral: Multidisciplinary prevention<br>* group cognitive training (every month) App-based Cognitive Training at Home (using smartphone application) physical activity/body weight/smoking & alcohol cessation monitoring and feedback<br>|
| No Intervention: Control group<br> | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change from Baseline Cognition at 6 month | Table-based cognitive screening test score | Baseline, 6months | 
| Change from Baseline Cognition at 1 year | Table-based cognitive screening test score | Baseline, 1year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Quality of life measures | Quality of life questionnaire | Baseline, 6months, 1year | 
| Change in Depression | Geriatric depression scale | Baseline, 6months, 1year | 
| Change in anxiety | Geriatric Anxiety Inventory | Baseline, 6months, 1year | 
| Change in Stress | Korean version of recognized stress scale | Baseline, 6months, 1year | 
| Change in Subjective memory | Multifactorial Memory Questionaire | Baseline, 6months, 1year | 
| Change in Activities of Daily Living | Korean version of Bayer ADL (Bayer Activities of Daily Living) | Baseline, 6months, 1year | 
| Change in Dementia Screening Questionnaire score | Korean Dementia Screening Questionnaire | Baseline, 6months, 1year | 
| Change in Prospective and retrospective memory | Prospective and retrospective memory questionnaire | Baseline, 6months, 1year | 
| Change in Mastery | Mastery questionnaire | Baseline, 6months, 1year |