A Trial for a Personalized Medication Management Platform to Improve Medication Adherence

Study Overview
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Brief Summary
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Taiwan has attracted much attention for its National Health Insurance (NHI) and healthcare system around the world with many countries in Europe and the United States using it as a benchmark. However, increasing medication costs over the past two years account for more than 25% of total expenditure, surpassing every OECD member and mounting increasing pressure on the NHI. Nevertheless, patient medication adherence is relatively low. Thus, the investigators assessed the effectiveness of a personalized medication management system for improving the medication adherence for patients, in order to save long term medication costs.

Detailed Description
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Design, Setting and Patients: The investigators developed a mobile personalized medication management platform (PMMP) to reduce delayed and missed medications. The investigators conducted a randomized control trial in medical centers of northern Taiwan from January 2010 to July 2012 using 1198 participants that missed or delayed their medications during past three days. They received a minimum 7-day to 14-day maximum medication prescription. Interventions: Patients were randomized into a control group which non-received any SMS reminder for medication using and an intervention group which received a SMS reminder everyday in mobile devices. Primary Outcome(s) and Measure(s): The primary outcomes were compared patient medication adherence among experimental and control groups.

Official Title
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Mobile Intelligent Personal Medication Management Platform

Conditions
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Patients Take Medicine

Intervention / Treatment
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* Device: Personalized Medication Management Platform for SMS Reminder


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Delayed or forgot to take medications over the last 3 days Received a min. 7-day medication prescription Able to receive SMS using mobile phones / devices 20 years or older Having intention to receive active treatment Exclusion Criteria: Unable to receive SMS via mobile phones Illiterate and < 20 years of age Received outpatient prescription drugs for ≤ 7 days External use, injections and traditional Chinese medicine Planned to go abroad Cold, cough, or prescribed with analgesics

Ages Eligible for Study
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Minimum Age: 20 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: SMS Medication Reminder<br>763 patients were assigned to experimental group | Device: Personalized Medication Management Platform for SMS Reminder<br>* The Personalized Medication Management Platform was developed by investigators that integrated with Hospital Information System (HIS) to collect the prescription information of patients and automatically send SMS to remind<br>|
| No Intervention: No SMS Reminder<br>435 patients were assigned to control group as no SMS reminder | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The proportion of patients in delaying and forgetting medications |  | Patients who participated in this trial will be sent SMS during 7days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Personalized Medication Management, Medication Adherence, SMS Medication Reminder