Effect of Hp Infection on the Quality of Gastric Mucosa Preparation

Study Overview
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Brief Summary
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The purpose of this study was to evaluate the effect of Helicobacter pylori infection on the quality of gastric mucosa preparation.

Detailed Description
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The purpose of this study was to evaluate the effect of Helicobacter pylori infection on the quality of gastric mucosa preparation by comparing the cleanliness of gastric mucosa between patients with Helicobacter pylori infection and those without Helicobacter pylori infection.

Official Title
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Effect of Hp Infection on the Quality of Gastric Mucosa Preparation and Study on Different Gastric Mucosa Preparation Schemes in Patients With Hp Infection

Conditions
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Helicobacter Pylori Infection

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adults who volunteered to participate in this study and signed an informed consent form Have been tested for Helicobacter pylori and have definite test results Exclusion Criteria: Contraindications for gastroscopy (such as severe cardiopulmonary diseases, liver and kidney dysfunction, shock, etc.) History of upper gastrointestinal surgery Therapeutic endoscopy and emergency surgery are required Recent history of upper gastrointestinal bleeding Corrosive substance ingestion The pregnancy Abnormal mental state cannot cooperate with the examination Patients with contraindications to the drugs used in the study.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients with Helicobacter pylori infection<br>Patients with H. pylori infection identified by testing for H. pylori. | |
| Patients not infected with Helicobacter pylori<br>Patients without H. pylori infection identified by H. pylori testing. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cleanliness of gastric mucosa | The visibility of gastric mucosa was scored for four parts of the stomach (antrum, upper body, lower body and fundus). | The time the patient underwent gastroscopy procedure | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Time to complete gastroscopy | The time from the start of the endoscopy to the complete removal of the endoscope | The day of gastroscopy | 
| Patient comfort score | Prior to endoscopy, the patient was instructed to indicate the level of discomfort on a visual analogue scale, which was rated by the patient on a scale of 0 to 10, with 0 indicating no discomfort and 10 indicating maximum discomfort. | Records were made on the 1 day of the gastroscopy | 
| adverse reaction | Adverse reactions to study drugs, and respiratory, cardiovascular, or endoscopic adverse events. | Within 24 hours after endoscopy | 
| Endoscopic findings | The diagnostic results were recorded under gastroscopy, and if the biopsy was taken under gastroscopy, the pathological results were also recorded | About 15 days after endoscopy |