Association Between a Peri-traumatic Dissociation State and the Occurrence of Post-traumatic Stress Syndrome

Study Overview
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Brief Summary
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Patients will be selected after studying clinical records.Patients who had general anesthesia due to an injury related to severe trauma within 6 to 12 months prior to inclusion will be included. Three self-survey will be completed by the patient: PDEQ, PCL-5 and a demographic questionnaire. According to the PDEQ and PCL-5 scores, an association between a peri-traumatic dissociation state and a post-traumatic stress disorder can be established.

Official Title
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Study of the Association Between a Peri-traumatic Dissociation State and the Occurrence of Post-traumatic Stress Syndrome After Severe Trauma Requiring General Anesthesia

Conditions
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Severe Trauma, General Anaesthesia

Intervention / Treatment
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* Diagnostic Test: PDEQ, PCL-5 and demographic survey


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients with general anesthesia for a surgical wound with violent trauma in the road, a fall of more than 6 meters, burn, accident at work, explosion, aggression) in the 6 to 12 months before the inclusion Time between trauma and general anesthesia should not exceed 48 hours Patient agreeing to participate in the study. Exclusion Criteria: Minor patients Patients under curatorship, and tutorship Patient deprived of liberty Patients who do not speak French Patients who are not in satisfactory neurological state to answer the questionnaire (pyschotic, demented states) Patients who have been sedated (apart from general anesthesia) when receiving or having a Glasgow score <14
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Intervention Model: Single Group Assignment
Interventional Model Description: Prospective Study
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: PDEQ, PCL-5 and demographic survey<br>State of the patient evaluated with questionnaires to make the connection between peri-traumatic dissociation and the occurrence of post-traumatic stress disorder | Diagnostic Test: PDEQ, PCL-5 and demographic survey<br>* Questionnaires<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Studying association between the presence of peri-traumatic dissociation state and the achievement of post-traumatic stress disorder between 6 and 12 months in traumatized patients | Association will be measured using PDEQ scale and PCL-5 scale. The peri-traumatic dissociation will be evaluated by the Peri-traumatique Dissociation Experience Questionnary (PDEQ scale). This questionnaire contains ten items to study the presence or not of a peri-traumatic dissociation state. The items are scored on a 5-point Likert scale ranging from 1 (not at all true) to 5 (extremely true). The total score is the sum of all the items. A score from 15 indicates a significant dissociation. The presence or not of a Post-Traumatic Stress Disorder (PTSD) will be evaluated by the Post-Traumatic Stress Disorder Checklist Scale-Version DSM 5 (PCL-5). This questionnaire contains twenty items to study the presence or not of a PTSD. A total score for symptom severity (0-80) can be obtained by summing the scores for each of the 20 items. A score over 31 indicates a PTSD. | study baseline (6 to 12 months after initial hospitalisation) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Measurement of the frequency of PTSD after severe trauma requiring general anesthesia. |  | study baseline (6 to 12 months after initial hospitalisation) | 
| Research of Risk Factors Associated with the Occurrence of PTSD |  | study baseline (6 to 12 months after initial hospitalisation) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Severe trauma, General anaesthesia, Peri-traumatic dissociation state, Post-traumatic stress disorder