SATIN WP4 Acute Effect on Appetite of Pineapple Juice With Viscofiber and Red Ginseng

Study Overview
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Brief Summary
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The objective of the study is to establish whether a Pineapple juice with Viscofiber and Red ginseng can enhance satiety and reduce appetite and/or accelerate satiation in the short-term.

Detailed Description
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A double-blind, randomised crossover design will be employed with an experimental (active) condition and a control condition at least one week apart. After having successfully completed screening procedures eligible participants will be invited for two separate test days, at least 7 days apart. On the two test days, the products will be provided in a randomized order as part of a fixed breakfast meal, and subjective appetite ratings will be measured every 30 min for the following 8 hours. Satiety and satiation will be measured through administration of test meals in the laboratory supplied with controlled food intake under free-living conditions

Official Title
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SATIN WP4 - The Acute Effect on Appetite of Pineapple Juice With Viscofiber and Red Ginseng

Conditions
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Healthy

Intervention / Treatment
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* Dietary Supplement: SATIN pineapple
* Dietary Supplement: SATIN pineapple control


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Participants who have provided written informed consent Healthy men and women Ages between 18 and 55 years BMI between 25.0-31.9 kg/m2 Regular breakfast eaters (eating breakfast ≥ 4 times a week) Regular menstrual periods (women only) Exclusion Criteria: Significant health problems as judged by the investigator Taking any medication or supplements known to affect appetite or body weight within the past month and/or during the study as judged by the investigator Pregnant, planning to become pregnant within the next 4 weeks or breastfeeding (women only) History of anaphylaxis to food Any known food allergies or food intolerance Smoking, smoking cessation within the past 3 months or nicotine use (electronic cigarettes) Self-reporting currently dieting or having lost/gained significant amount of weight (±3 kg) in the previous 3 months Significant changes in physical activity patterns in the past 4 weeks or intention to change during the study as judged by the investigator Significant change in diet in the past 4 weeks or intention to change the diet during the study as judged by the investigator Use of systemic or local treatment likely to interfere with evaluation of the study parameters as judged by the investigator Participants who work in appetite or feeding related areas Participants not able to comply with the study protocol Post-menopausal (women only)

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 55 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Active<br>Satin pineapple. Active juice with fibre and ginseng | Dietary Supplement: SATIN pineapple<br>* Active juice with added fibre and ginseng<br>|
| Placebo Comparator: Control<br>SATIN pineapple control. Control juice - normal juice prpoducts without added active ingredients | Dietary Supplement: SATIN pineapple control<br>* Control products without active ingredients<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Ad libitum energy intake | Total ad libitum energy intake during test day 1 | Baseline (week 0) | 
| Ad libitum energy intake | Total ad libitum energy intake during test day 2 | Test day 2 (week 1) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| VAS score for appetite sensation - hunger | Perceptions of hunger, assessed using 100 mm VAS scales | Every 30 min during test day 1 and test day 2 | 
| Eating behaviour questionnaire - binge eating scale | Questionnaire by Gormally et al. 1982 | Screening | 
| Eating behaviour questionnaire - Control of Eating | Questionnaire by Hill et al. 1991 | screening | 
| Eating behaviour questionnaire - three factor eating questionnaire | Three Factor Eating Questionnaire by Stunkard and Messick, 1985 | screening | 
| Eating behaviour questionnaire- power of food | Power of food scale by Lowe et al 2009 | screening | 
| VAS score for appetite sensation - fullness | Perceptions of fullness, assessed using 100 mm VAS scales | every 30 min during test day 1 and test day 2 | 
| VAS score for appetite sensation - Desire to eat | Perceptions of Desire to eat, assessed using 100 mm VAS scales | every 30 min during test day 1 and test day 2 | 
| VAS score for appetite sensation - prospective consumption | Perceptions of prospective suncumption, assessed using 100 mm VAS scales | every 30 min during test day 1 and test day 2 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Ad libitum energy intake, Appetite