Comparing the Effect of the Water Drinking Test on Intraocular Pressure

Study Overview
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Brief Summary
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A test that was common in the 1960's and was used to detect primary open angle glaucoma was the water drinking test (patients drank 1 quart of water to stress the fluid drainage mechanism of the eyes. Intraocular pressure was then measured over the next hour). Recently this test has been demonstrated as a predictor of peak eye pressure during the day. The purpose of this study is to compare the results of the water drinking test between eyes that have undergone trabeculectomy and eyes that have undergone tube shunt surgery.

Official Title
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Comparing the Effect of the Water Drinking Test on Intraocular Pressure in Patients With Prior Trabeculectomy or Tube Shunt Surgeries

Conditions
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Glaucoma

Intervention / Treatment
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* Procedure: Water Drinking Test


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: prior trabeculectomy or tube shunt for the treatment of glaucoma age 21-90 years Exclusion Criteria: inability to give informed consent current ocular infection more than 1 prior trabeculectomy, or more than 1 prior tube shunt previous refractive surgery pregnant women heart failure renal failure or uncontrolled urine retention corneal abnormalities preventing reliable IOP measurement

Ages Eligible for Study
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Minimum Age: 21 Years
Maximum Age: 90 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Trabeculectomy<br>Individuals in this group will have undergone a trabeculectomy for the treatment of glaucoma. | Procedure: Water Drinking Test<br>* The Water Drinking test has been identified as a reliable and safe tool to predict maximum intraocular pressure values during a diurnal tension curve and to assess the efficacy of surgical interventions. Participants are asked to drink 10 ml/kg water (or approximately 0.33 ounces of water for every 2.2 pounds of weight or about 2.5 cups for a 150 lb. individual) over 15 minutes. Intraocular pressure is assessed every 15 minutes for one hour.<br>|
| Tube Shunt<br>Individuals in this group will have undergone a tube shunt for the treatment of glaucoma. | Procedure: Water Drinking Test<br>* The Water Drinking test has been identified as a reliable and safe tool to predict maximum intraocular pressure values during a diurnal tension curve and to assess the efficacy of surgical interventions. Participants are asked to drink 10 ml/kg water (or approximately 0.33 ounces of water for every 2.2 pounds of weight or about 2.5 cups for a 150 lb. individual) over 15 minutes. Intraocular pressure is assessed every 15 minutes for one hour.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Intraocular Pressure (IOP) | IOP is assessed every 15 minutes for one hour after the water drinking test is complete. | 1 hour | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Water drinking test, trabeculectomy, tube shunt