Effects of Snack Types on Acute Glucose and Insulin Response

Study Overview
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Brief Summary
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The purpose of the present study was to determine the effects of different type of snack consumption on postprandial satiety, glucose, insulin, antioxidant capacity and anxiety in healthy subjects.

Official Title
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Effects of Snack Types on Acute Glucose and Insulin Response

Conditions
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Satiety

Intervention / Treatment
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* Other: Pretzels
* Other: Brazil nuts
* Other: Potato chips
* Other: Mixed nuts
* Other: White bread
* Other: Dried mango
* Other: Mango fruit


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 18-55 years old Exclusion Criteria: Smoker Pregnant woman Required dietary supplement use Required medication of metabolic disorders Allergy to nuts or gluten (wheat)

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 55 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Pretzels<br>Subjects consume pretzels to examine postprandial response | Other: Pretzels<br>* To examine postprandial responses of pretzel consumption<br>|
| Experimental: Brazil nuts<br>Subjects consume Brazil nuts to examine postprandial response | Other: Brazil nuts<br>* To examine postprandial responses of Brazil nut consumption<br>|
| Active Comparator: Potato chips<br>Subjects consume potato chips to examine postprandial response | Other: Potato chips<br>* To examine postprandial responses of potato chip consumption<br>|
| Experimental: Mixed nuts<br>Subjects consume mixed nuts to examine postprandial response | Other: Mixed nuts<br>* To examine postprandial responses of mixed nut consumption<br>|
| Active Comparator: White bread<br>Subjects consume white bread to examine postprandial response | Other: White bread<br>* To examine postprandial responses of white bread consumption<br>|
| Experimental: Dried mango<br>Subjects consume dried mango to examine postprandial response | Other: Dried mango<br>* To examine postprandial responses of dried mango consumption<br>|
| Experimental: Mango fruit<br>Subjects consume fresh mango to examine postprandial response | Other: Mango fruit<br>* To examine postprandial responses of fresh mango consumption<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change of Satiety | Hunger feeling (appetite) will be examined using visual analog scale (0-10): 0 least and 10 greatest | 0, 20, 40, 60, 90 and 120 minutes post snack consumption | 
| Change of glucose level | Blood will be collected by finger pricks and change of glucose level will be examined. | 0 and 40 minutes post snack consumption | 
| Change of insulin level | Blood will be collected by finger pricks and change of insulin level will be examined | 0 and 40 minutes post snack consumption | 
| Change of anxiety feeling | Anxiety feeling will examined using STAI (Spielberger Stasumte-Trait Anxiety Inventory) questionnaire (1-4): 1 least and 4 greatest, total summed score will be used. | 0 and 40 minutes post snack consumption | 
| Change of antioxidant level | Blood will be collected by finger pricks and change of antioxidant level will be examined | 0 and 40 minutes post snack consumption |