Prevalence of Endometriosis in a Well Defined Group of Infertile Women

Study Overview
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Brief Summary
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At the Leuven University Fertility Centre (LUFC) of the Department of Obstetrics and Gynecology of the University Hospitals Leuven, Belgium, a retrospective epidemiological prevalence study based on an electronic search of patient files was performed to determine the prevalence of histologically proven endometriosis in a subset of infertile women with a regular cycle (variation 21 - 35 days), a partner with normal sperm and no previous surgical diagnosis of endometriosis.

Detailed Description
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In this study, the electronic files of all patients who consulted the LUFC since 2003 were searched to select women with at least 1 year of infertility, a regular cycle (variation 21 - 35 days), whose partner had normal sperm according to World Health Organization (WHO) criteria (n = 304). After exclusion of 83 (27,3%) patients with a previous laparoscopic diagnosis of endometriosis before referral to our centre, 221 (72,7%) infertile women were included in our study.

Official Title
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High Prevalence of Endometriosis in Infertile Women With Normal Ovulation and Normospermic Partners

Conditions
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Endometriosis, Infertility

Intervention / Treatment
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* Procedure: Laparoscopy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: all patients who consulted the LUFC since 2003 with at least 1 year of infertility, a regular cycle (variation 21 - 35 days), whose partner had normal sperm according to World Health Organization (WHO) criteria. Exclusion Criteria: a previous laparoscopic diagnosis of endometriosis before referral to our centre

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| 1<br>The electronic files of all patients who consulted the LUFC since 2003 were searched to select women with at least 1 year of infertility, a regular cycle (variation 21 - 35 days), whose partner had normal sperm according to World Health Organization (WHO) criteria (n = 304). After exclusion of 83 (27,3%) patients with a previous laparoscopic diagnosis of endometriosis before referral to our centre, 221 (72,7%) infertile women were included in our study. | Procedure: Laparoscopy<br>* Laparoscopy<br>* Other names: CO2 laser operative laparoscpy;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The diagnosis of endometriosis was made by the fertility surgeon of the LUFC. |  | 2003 - 2006 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The diagnosis of endometriosis was always confirmed by histological examination. |  | 2003 - 2006 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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endometriosis, prevalence, fertility, pain, ultrasound