Impact of Hemodialysis on Cutaneo-muscular Electrical Impedance

Study Overview
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Brief Summary
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The primary objective of this pilot study aims to describe the modifications of subcutaneous impedancemetry induced by dialysis. As secondary objectives, the study aims to 1) describe the modifications of cutaneo-muscular impedancemetry induced by dialysis. 2) describe the relationship between modifications of subcutaneous impedancemetry induced by dialysis and - technical conditions of dialysis; - volemic parameters of dialysis; - evolution of liquid compartments in organism during dialysis; - volemic events or neuromuscular events. 3) describe the relationship between modifications of cutaneo-muscular impedancemetry induced by dialysis and 1) describe the modifications of cutaneo-muscular impedance induced by dialysis. 2) describe the relationship between modifications of subcutaneous impedancemetry induced by dialysis and - technical conditions of dialysis; - volemic parameters of dialysis; - evolution of liquid compartments in organism during dialysis; - volemic events or neuromuscular events.

Detailed Description
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The study will be realized in dialysis facility of Ambroise Paré hospital, APHP. The duration of enrollment of subjects will be 3 months, each enrolled patient will has 2 or 3 week's follow-up.

Official Title
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Impact of Hemodialysis on Cutaneo-muscular Electrical Impedance

Conditions
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Hemodialysis

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patient ⩾ 18 years; Patient undergoing chronic dialysis in hemodialysis facility of Ambroise Paré hospital; Patient has been informed and given no-opposition for participating to the study. Exclusion Criteria: Patient with a pacemaker or an implantable cardioverter defibrillator; Patient under guardianship or curatorship; Foreign patient under french AME scheme.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 89 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Electrical parameters of subcutaneous impedancemetry | Electrical parameter extracellular resistance (Re) will be assessed. | at the end of study, up to 4 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cutaneo-muscular impedancemetry assessement | Cutaneo-muscular impedancemetry will be assessed by extracellular resistance (Re). | at the end of study, up to 4 months | 
| Whole body impedancemetry assessement | Whole body impedancemetry will be assessed by Re. | at the end of study, up to 4 months | 
| Incidence of volemic or neuromuscular events | Incidence of volemic or neuromuscular events during the session, such as: peridialytic hypotension, crampses. | at the end of study, up to 4 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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hemodialysis, electrical impedance, subcutaneous impedancemetry, cutaneo-muscular impedancemetry