Impact of Smoking on the Effectiveness of Non Surgical Treatment of Peri-implant Mucositis

Study Overview
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Brief Summary
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The aim of the present study was to test the hypothesis that smoking impact non-surgical periodontal therapy results in a greater clinical improvement in patients with peri-implant mucositis.

Detailed Description
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The aim of the present study was to test the hypothesis that the smoking levels at baseline influence full mouth disinfection results in a greater clinical and microbiological improvement compared with sole mechanical debridement within one session in patients with peri-implant mucositis.

Official Title
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Impact of Smoking at Baseline on the Effectiveness of Non Surgical Treatment of Peri-implant Mucositis: a Randomized Controlled Clinical Trial

Conditions
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Peri-implant Mucositis

Intervention / Treatment
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* Other: Non surgical peri-implant mucositis therapy with one-stage full-mouth scaling
* Other: Non surgical peri-implant mucositis therapy with one-stage full-mouth scaling and chlorexidine


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: peri-implant mucositis bleeding on probing and/or a gingival index <1 at least at one site at baseline absence of peri-implant bone loss during the last 2 years before baseline Exclusion Criteria: Periodontal disease Systemic diseases

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: After randomized assignment to a test and a control group, patients received a one-stage full-mouth scaling with or without chlorhexidine. Clinical and microbiological examination was performed at baseline, after 1, 3, and 6 months.
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Placebo Comparator: SRP and no chlorhexidine<br>Patients received a one-stage full-mouth scaling without chlorhexidine performed in one session of full mouth scaling and root planing. | Other: Non surgical peri-implant mucositis therapy with one-stage full-mouth scaling<br>* Patients were treated with full mouth non surgical peri-implant mucositis therapy performed with only full mouth scaling and root planing<br>|
| Active Comparator: SRP plus 0.12% chlorhexidine<br>Patients received a one-stage full-mouth scaling with 0.12% chlorhexidine performed in one session of full mouth scaling and root planing. | Other: Non surgical peri-implant mucositis therapy with one-stage full-mouth scaling and chlorexidine<br>* Patients were treated with full mouth non surgical peri-implant mucositis therapy performed with only full mouth scaling and root planing and chlorexidine<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes of probing depth at implant sites | Probing depth changes | 3-months |