linjc16/ctgov huggingface dataset:
HIP Surgery - Hemodynamic Optimization Project

Study Overview
=================
Brief Summary
-----------------
Several studies have demonstrated that goal-directed fluid therapy during high- risk-surgery reduces morbidity and length of hospital stay. This quality improvement is design to evaluate the implementation of an intraoperative goal-directed therapy, using a pulse contour analysis monitor to optimize the stroke volume, in patients undergoing redo-hip-surgery. The primary combined endpoints will be the incidence of postoperative complications and the secondary endpoints will be the decrease of hospital length of stay, length of ICU stay and hospital postoperative mortality. We amended another 130 patients getting crystalloid fluids in the hemodynamic optimization protocol.

Official Title
-----------------
A Quality Improvement Project for Goal-directed Intraoperative Hemodynamic Optimization in Patients Redo Hip Surgery

Conditions
-----------------
Redo Hip Surgery

Intervention / Treatment
-----------------
* Device: Stroke volume monitoring


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients undergoing redo hip surgery age above 18 years signed informed consent Exclusion Criteria: urgent or emergency surgery

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Supportive Care
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: Standard care<br>No specific hemodynamic optimization measures | |
| Experimental: Hemodynamic optimization<br>Hemodynamic optimization by stroke volume monitoring | Device: Stroke volume monitoring<br>* Pulse contour stroke volume monitoring<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| postoperative complications |  | 30days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| length of hospital and ICU stay |  | 30days |
Quality of Life After Wide Surgical Excision in Patients With Hidradenitis Suppurativa

Study Overview
=================
Brief Summary
-----------------
Patients undergoing wide surgical excision of their hidradenitis suppurativa areas are asked by telephone about their quality of life by standard questionnaires (WHOQOL-BREF, DLQI, Skindex, MHF, FLQA-d) and their sexual function (FSFI, IIEF).

Official Title
-----------------
Quality of Life After Wide Surgical Excision in Patients With Hidradenitis Suppurativa

Conditions
-----------------
Hidradenitis Suppurativa, Wide Excision

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Hidradenitis suppurativa that was wide excised in 2013 in Fachklinik Hornheide Agreed to retrospective analysis and questionnaires Exclusion Criteria: Non-compliance
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Quality of Life (WHOQOL-BREF) | Quality of Life is checked by WHOQOL-BREF | 2 years postop | 
| Quality of Life (DLQI) | Quality of Life is checked by DLQI | 2 years postop | 
| Quality of Life (FLQA-d) | Quality of Life is checked by FLQA-d | 2 years postop | 
| Quality of Life (Skindex) | Quality of Life is checked by Skindex | 2 years postop | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Sexual Function | Sexual Function is checked by IIEF (male) and FSFI (female) | 2 years postop | 
| Demographic Parameters | Patients' history | 2 years postop | 
| Smoking | Smoking | 2 years postop | 
| Weight and height | Weight and height | 2 years postop | 
| Wound assessment | Localization, Hurley Stage, pain before operation | 2 years postop | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Hidradenitis suppurativa, Wide excision, Quality of Life, Sexual Function
A Crowd Sourcing Platform for Patients With Cancer

Study Overview
=================
Brief Summary
-----------------
All4Cure aims to accelerate learning about cancer by sharing medical information and research results from cancer patients with fellow cancer patients, oncologists, and scientists on the All4Cure website with the hope that together patients, clinicians and researchers can cure cancer faster.

Detailed Description
-----------------
The core hypothesis tested by this study is that engaging researchers, clinicians and patients in an online knowledge sharing platform will enable patients to better understand cancer, better inform treatment decisions made by oncologists and accelerate cancer research. Leftover samples from patients with cancer (blood, bodily fluids and/or tissues collected for clinical purposes) will be obtained and sent for various types of analyses and results will be shared on the All4Cure website.

Official Title
-----------------
A Crowd Sourcing Platform for Patients With Cancer

Conditions
-----------------
Cancer

Intervention / Treatment
-----------------
* Other: No intervention


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Have been diagnosed with cancer. Be under the care of a physician. Be 18 years of age or older. Exclusion Criteria:

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: No intervention|No Intervention|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in tumor tissue molecular profiles | Profiles of pre- and post-treatment tumor tissue will be compared. | 6 years |
Outcome of Arterio-venous Fistula for Adult Hemodialysis Patients in Assiut Governorate

Study Overview
=================
Brief Summary
-----------------
identification of the factors that affect the outcome of arteriovenous fistula in chronic renal failure patients that newly established regular dialysis in Assiut Governorate To study the factors that influence the outcome of AVF To evaluate the vascular complications of AVF as occlusion, rupture, aneurysmal dilation and hand ischemia

Official Title
-----------------
Outcome of Arterio-venous Fistula for Adult Hemodialysis Patients in Assiut Governorate

Conditions
-----------------
Chronic Renal Failure

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: all adult hemodialysis Patients in Assiut Government are eligible for enrollment if they are newly dialyzed via AVF and agree to participate in the study Exclusion Criteria: Patients are not dialyzed with AVF

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the number of new renal failure patients with failed arteriovenous fistula as measured with arteriovenous duplex ultrasound imaging peak systolic velocity and end-diastolic velocity in Assiut Governorate | the arteriovenous fistula will be named fail if one or more of the following No Doppler signal Ratio of peak systolic velocity at stenosis to peak systolic velocity at 2 cm beyond anastomosis (if normal)appearing >3 Intraluminal echogenicity Graft walls appear collapsed | 3 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the number deaths of renal failure patients on regular dialysis related to AVF complications in Assiut Governorate |  | 3 years |
SCOT Registry: Small Cell Lung Cancer Treatment and Outcome

Study Overview
=================
Brief Summary
-----------------
The registry is an international, multicenter, observational registry of newly diagnosed patients with SCLC. Data will be entered into an electronic CRF (eCRF) via Internet access. Treatment plan remains the responsibility of the patient's physician and data collected in this registry will reflect a real world approach of the diagnosis and treatment of patients with SCLC. Approximately 60 centres in 13 countries will take part in this registry. It is expected that about 500 patients will be recruited during a period of 6 to 9 months according to the feasibility.

Official Title
-----------------
SCOT Registry: Small Cell Lung Cancer Treatment and Outcome

Conditions
-----------------
Lung Cancer, Small Cell

Intervention / Treatment
-----------------
* Drug: HYCAMTIN


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Male or Female >/= 18 years Diagnosis of small cell lung cancer Patient newly diagnosed with SCLC Has given written informed consent (if applicable) Exclusion Criteria: Concurrent history of other neoplasm, except curatively treated basal cell skin cancer or adequately treated in-situ carcinoma of the cervix. Patient presenting with recurrence of SCLC. Patients who has received any chemotherapy for the SCLC.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| HYCAMTIN<br> | Drug: HYCAMTIN<br>* Observing patients on HYCAMTIN and other drugs for SCLC.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Registry with disease, treatment and outcome data collected. |  | 6-9mth recruitment period, 18mth study duration. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| survival rates |  | 18 month period |
Missed Serious Medical Illness in Psychiatric Patients Seen in an Academic Emergency Department

Study Overview
=================
Brief Summary
-----------------
Psychiatric presentations are common in the emergency department (ED), and determining whether or not a psychiatric presentation is due to medical illness can be a difficult task for the emergency physician. The investigators define serious medical illness (SMI) as a pathological condition that would necessitate inpatient treatment on a medical or surgical ward. It is important for patient safety that SMI be triaged by the emergency physician to the appropriate inpatient service. The rate of missed SMI in patients with psychiatric presentations to the ED is unknown. The investigators will research missed SMI in patients referred to adult psychiatry from the ED, with the intent to improve patient safety.

Official Title
-----------------
Missed Serious Medical Illness in Psychiatric Patients Seen in an Academic Emergency Department

Conditions
-----------------
Emergency Services, Psychiatric

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: All patients greater than or equal to 18 years of age presenting to London Health Sciences Centre, Victoria Hospital emergency department between October 1, 2014 - July 31, 2015 who were referred to adult psychiatry by the emergency physician. Exclusion Criteria: None

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of patients admitted to a medical / surgical service within 7 days of psychiatry referral in the emergency department |  | Approximately 8 months | 
| Medical / surgical admission diagnosis | This will be extracted from the electronic medial record. | Approximately 8 months | 
| Number of days after psychiatric referral that patient is admitted to medical / surgical service |  | Approximately 8 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Proportion of patients discharged home from the emergency department by psychiatry following referral by the emergency physician |  | Approximately 8 months | 
| Risk factors associated with medical / surgical admission after initial psychiatry referral | The investigators will be extracting variables from the patient's chart including triage vital signs, past medical and psychiatric history, initial laboratory bloodwork, and determining if any of these are risk factors for subsequent medical / surgical admission. | Approximately 8 months | 
| Number of admissions to medical / surgical service within 30 days of discharge from psychiatry |  | Approximately 8 months |
Dental Health Epidemiology Among Israel Defense Forces (IDF) Recruits

Study Overview
=================
Brief Summary
-----------------
An epidemiological survey for prevalence description of dental morbidity (caries, gingivitis, dental trauma and fluorosis) among Israel Defense Forces (IDF) general recruits. Morbidity measures were collected from 700 recruits at their first day of military service in order to evaluate extent and burden of dental diseases among recruits. The data will enable the military dental services commanders to plan and implement dental services according to the dental needs.

Detailed Description
-----------------
Caries, gingivitis, dental trauma and fluorosis epidemiological measures were collected among IDF recruits in 700 sample using short clinical evaluation without radiographs. water fluoridation ecological data will be obtained from the ministry of health. the results might impact dental services plan, professional manpower system, and the layout of the dental clinics in the IDF. It will give the professionals in the military dental services an evidence based data for planning an accurate primary and secondary prevention programs and an evaluation of dental diseases burden in order to have the full picture of recruits dental needs. .

Official Title
-----------------
Caries, Gingivitis, Dental Trauma and Fluorosis Prevalence Among IDF Recruits - an Epidemiological Survey

Conditions
-----------------
Caries, Dental, Gingivitis, Fluorosis, Dental Trauma

Intervention / Treatment
-----------------
* Other: Data collection


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Above 18 years old. Exclusion Criteria: Chronic bone diseases. Mineralization defects

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Data collection|Collection epidemiological dental measures|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| DMFT index (Decayed, Missing, Filled, Tooth) |  | 7 days | 
| CPI (Community Periodontal Index) index |  | 7 days | 
| TDI (Dental Trauma Index) index |  | 7 days | 
| TF (Thylstrup & Fejerskov Index for dental Fluorosis) index |  | 7 days |
Investigating Temporal Improvements in Survival Following ST-elevation Myocardial Infarction.

Study Overview
=================
Brief Summary
-----------------
The aim of the study was to use data from the Myocardial Ischaemia National Audit Project (MINAP) to investigate whether temporal improvements in survival were associated with changes in patients' baseline clinical risk or use of guideline-indicated treatments for the management of STEMI, and to determine the extent to which associations explained the temporal improvements in survival.

Official Title
-----------------
Investigating Temporal Improvements in Survival Following ST-elevation Myocardial Infarction: A Causal Mediation Analysis Using the Myocardial Ischaemia National Audit Project, 2004-2013.

Conditions
-----------------
Acute Myocardial Infarction

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: aged 18 years or more patients hospitalised with ST-elevation myocardial infarction Exclusion Criteria: patients hospitalised with phenotypes other than ST-elevation myocardial infarction

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| All cause mortality |  | one year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| All cause mortality |  | six months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
mortality, Acute Myocardial Infarction, evidence-based care, Myocardial Ischaemia National Audit Project, ST-elevation myocardial infarction
COVID-19 Amyotrophic Lateral Sclerosis (ALS) Registry

Study Overview
=================
Brief Summary
-----------------
Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive and fatal neurodegenerative disease characterized by progressive weakness involving limb, bulbar, and respiratory muscles.There is currently no information suggesting how COVID-19 affects patients diagnosed with amyotrophic lateral sclerosis (ALS). This is especially important as respiratory compromise is common in ALS patients and can complicate the clinical course as COVID-19 could lead to respiratory failure and need for intubation. We intend that this registry will guide our understanding of how COVID-19 affects patients with ALS.

Detailed Description
-----------------
The purpose of this registry is to assess the incidence and prevalence of COVID-19 in ALS patients, the effect of COVID-19 on ALS disease trajectory, and the impact, if any, of edaravone, riluzole and other concomitant medication used in ALS like Albuterol and dextromethorphan/quinidine (Nuedexta) on these parameters. COVID-19 incidence and prevalence in the ALS population will be assessed through outcomes reporting ranging from recovered infections to patient death reported in a patient facing registry.

Official Title
-----------------
COVID-19 Amyotrophic Lateral Sclerosis (ALS) Registry

Conditions
-----------------
Covid19, Amyotrophic Lateral Sclerosis

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Diagnosis of ALS and A confirmed COVID-19 infection determined by: positive SARS-CoV-2 viral RNA PCR test and/or positive serology antibody testing for SARS-CoV-2 Exclusion Criteria: No ALS diagnosis No confirmed COVID-19 infection

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| COVID-19 incidence and prevalence in the ALS population | Assessed through outcomes reporting ranging from recovered infections to patient death reported in a patient facing registry. | Data will be collected through study completion, an average of 3 years |
Tongue Image Database and Diagnostic Model for Digestive Tract Disease Diagnosis

Study Overview
=================
Brief Summary
-----------------
The tongue images of patients with gastrointestinal diseases and healthy people will be collected and the tongue image database will be established. Through deep learning and artificial intelligence, early screening models of various gastrointestinal tumors based on tongue images were constructed.

Official Title
-----------------
Tongue Image Database and Diagnostic Model for Digestive Tract Disease Diagnosis

Conditions
-----------------
Liver Diseases, Digestive Tract Diseases, Colorectal Disease, Gastric Diseases, Small Bowel Disease

Intervention / Treatment
-----------------
* Other: Tongue images，coating on the tongue and clinical data


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Be older than 18 years old; Clinical or pathological diagnosis of Digestive tract diseases; Patients before receiving surgery, chemotherapy, radiotherapy, targeted therapy, local therapy, immunotherapy and other treatment measures； The patient had no tongue disease Patients understand and are willing to sign written informed consent. Exclusion Criteria: Patients unable to complete the process as required (mental disorder or poor compliance, etc.); The patient or guardian is unwilling to participate in this study; Combined with other serious systemic diseases (heart failure, renal failure,hematopoietic system disease or Uncontrollable acute infection);

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| People with digestive tract diseases<br> | Other: Tongue images，coating on the tongue and clinical data<br>* Take photos of the tongue of patients with gastrointestinal diseases and collect clinical information.<br>|
| Healthy people<br> | Other: Tongue images，coating on the tongue and clinical data<br>* Take photos of the tongue of patients with gastrointestinal diseases and collect clinical information.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Diagnosis | The differences of tongue images between patients with digestive tract diseases and healthy people | 1 year |