Cognitive Interference Task on Alcohol Craving and Consumption

Study Overview
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Brief Summary
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The purpose of this study is to test a brief task of playing the game Tetris to reduce alcohol cravings and alcohol use. Women who are seen at primary care and recruited through the community will be asked to rate alcohol craving and use, and play the Tetris game on their phones daily for a 3-week period. Participants will also complete a cue-reactivity task, that involves viewing pictures of alcohol and rating cravings.

Official Title
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Effects of a Cognitive Interference Task on Alcohol Craving and Consumption Among Women

Conditions
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Alcohol Drinking, Craving

Intervention / Treatment
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* Behavioral: Tetris and Assessments
* Other: Assessment Only


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Female, any race or ethnicity, age 21 to 65 years old. Able to comprehend English. At least one heavy drinking per week (i.e., consuming at least four or more drinks in one day) for the last two weeks Internet access and reliable electronic device Exclusion Criteria: More than four heavy drinking days per week. Currently engaged in treatment for AUD. Current clinically significant bipolar affective disorder, schizophrenia, or psychotic disorder. Pregnant. Imminently suicidal or homicidal. Participants taking psychoactive medications that may affect alcohol craving or consumption. A score of 10 or higher on the Clinical Institute of Alcohol Withdrawal Revised (CIWA-R).24

Ages Eligible for Study
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Minimum Age: 21 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Cognitive Interference Task<br>Participants in this arm will complete random assessments of alcohol use and cravings on their phone, and be prompted to play Tetris on their phone after reporting cravings for alcohol. | Behavioral: Tetris and Assessments<br>* Participants will complete assessments on their phone to rate cravings for alcohol. Participants will complete a visual cognitive interference task (i.e., play Tetris on their phone) after endorsing a alcohol craving, and then re-rerate craving after the task.<br>|
| Active Comparator: Assessment Only<br>Participants in this arm will complete random assessments of alcohol use and cravings on their phone. | Other: Assessment Only<br>* Participants will complete assessments on their phone to rate cravings for alcohol.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes on Craving for Alcohol Before and After Tetris Task | Participants will complete items from the Craving Experiences Questionnaire. | Participants will report cravings at baseline, during the intervention phase, within one-week after the intervention, and one-month after the intervention. | 
| Changes in Alcohol Consumption Before and After Tetris Task | Participants will complete the Time Line Follow Back. | Participants will report alcohol consumption at baseline, during the intervention phase, within one-week after the intervention, and one-month after the intervention. | 
| Changes in Alcohol Consumption Before and After Tetris Task | Participants will be asked to record the number of drinks they had before the last assessment. | Participants will report alcohol consumption at baseline, during the intervention phase, within one-week after the intervention, and one-month after the intervention. | 
| Changes in Alcohol Craving Before and After Tetris Task | Participants will rate their craving on a single item from the Visual Analogue Craving Scale. | Participants will report alcohol consumption at baseline, during the intervention phase, within one-week after the intervention, and one-month after the intervention. | 
| Changes in Alcohol Craving Before and After Cue Tetris Task | Participants will rate their craving on a single item from the Visual Analogue Craving Scale. | Participants will report alcohol consumption at baseline, during the intervention phase, within one-week after the intervention, and one-month after the intervention. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes in Alcohol Craving Before and After Task | Participants will rate their craving and drinking behavior on the Obsessive Compulsive Drinking Scale. | Participants will report alcohol consumption at baseline, within one-week after the intervention, and one-month after the intervention. | 
| Changes in Drinking Motives Before and After Task | Participants will rate their drinking motives on the Drinking Motives Questionnaire. | Participants will report alcohol consumption at baseline, within one-week after the intervention, and one-month after the intervention.. | 
| Feasibility of Intervention | The proportion of prompts participants respond to, and the response time to complete prompts. | This will be recorded during the intervention phase. | 
| Acceptability Ratings | Participants will rate acceptability of the intervention on the Acceptability of Intervention Measure. | This will be recorded within one-week after the intervention. | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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ecological momentary assessment, cognitive interference