Validation of Instruments Used for Assessment of Dysphagia in Patients With Esophageal Cancer

Study Overview
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Brief Summary
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This study validates 3 well known dysphagia scores for dysphagia due to malignancies of the oesophagus and gastro-oesophageal junction and to the Swedish language.

Detailed Description
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In the present study, our aim was to firstly, validate 3 commonly used scales for use in patients with dysphagia due to malignancy, and secondly, to validate them in the Swedish language. The 3 scales were: The Watson dysphagia scale, which was developed in studies on surgical treatment of reflux disease. It consists of questions about food with 9 different viscosity and solidity and the patient answer if they have problems with a specific food: never, sometimes or always when ingesting this. The scores are added and provides a range of 0-45 where 45 is the worst possible dysphagia. The Ogilvie score is a 5-graded scale 0-4 where 4 is total inability to swallow. The Goldschmid score is graded from 0-5 where 0 is inability to swallow and 5 is normal function. QoL was measured with validated instruments originating from the European Organization for Research and Treatment of Cancer (EORTC), which has a generic instrument that measures global QoL in patients with cancer (QLQ-C30) and a more symptom-specific instrument that is developed for cancer in the oesophagus and stomach (QLQ-OG25). These are well known, validated instruments that also have normal reference values for the healthy population. The symptom specific instrument QLQ-OG25 includes a dysphagia module consisting of 3 questions which is validated to malignant disease and food intake with the help of expert groups and deep interviews with patients.

Official Title
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Validation of Instruments Used for Assessment of Dysphagia in Patients With Esophageal Cancer

Conditions
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Dysphagia, Esophageal, Esophageal Cancer

Intervention / Treatment
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* Other: Validation of different dysphagia scores


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Cancer in the gastro-esophageal junction or in the esophagus Dysphagia Ability to fill in the questionnaires Written acceptance of the informed consent Exclusion Criteria: Not for-filling inclusion criteria No consent
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients<br>Patients with oesophageal cancer and dysphagia | Other: Validation of different dysphagia scores<br> <br> * Other names: Validation to the Swedish language;|
| Controls<br>Healthy Controls with no known dysphagia | Other: Validation of different dysphagia scores<br> <br> * Other names: Validation to the Swedish language;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Validation of dysphagia scores |  | 10-14 days | 
| Translation of scores to the Swedish language |  | 10-14 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Cancer of the gastro-esophageal junction, Watson score, Ogilvie score, Goldschmid score, Validation, Quality of Life