Efficacy of Dual Task Training on Children With Ataxia After Medulloblastoma Resection

Study Overview
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Brief Summary
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The aim of this study is to evaluate the effect of using a selected dual-task- training program to improve postural stability in children with ataxia after medulloblastoma resection. Thirty patients will participate in this study. Patients will be classified randomly into two equal groups: study and control groups -Both groups will receive conventional physical therapy treatment including mobility exercises, balance exercises, gait training exercises, and exercises to improve physical conditioning. In addition, the study group will receive a selected dual-task training program including balance and cognitive activities. The treatment program will be conducted three days per week for eight successive weeks. The patients will be assessed with the Scale of Assessment and Rating of Ataxia, Humac Balance System, the Pediatric Balance Scale and Functional Independent Measurement. The measures will be recorded two times: before the application of the treatment program (pre) and after the end of the treatment program (post).

Official Title
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Efficacy of Dual Task Training on Children With Ataxia After Medulloblastoma Resection: (A Randomized Controlled Trial)

Conditions
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Ataxia, Medulloblastoma

Intervention / Treatment
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* Other: Dual Task Training (Motor + Cognitive)
* Other: Traditional Regular Exercise


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All children with the following criteria will be in rolled in the study Age range from (5-10 years). Severity of ataxia will be from 15-30 by SARA scale. Children after 2 months of medulloblastoma resection. They can stand and walk with minimal support. They have good cognition, compliance, and ability to understand and instructions. Children receiving radiotherapy and chemotherapy sessions They are medically stable Exclusion Criteria: Children will be excluded from the study if they have Any neuromuscular disorder. Visual impairment. Cognitive problem Convulsion. Peripheral neuropathy due to chemotherapy.

Ages Eligible for Study
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Minimum Age: 5 Years
Maximum Age: 10 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Dual Task Training<br> | Other: Dual Task Training (Motor + Cognitive)<br>* Each child in this group will perform one-hour session consist of two tasks (cognitive and balance task) in addition to the traditional physical therapy program three times weekly for 8 successive weeks.<br>|
| Active Comparator: Ordinary Physical Therapy for Ataxia<br> | Other: Traditional Regular Exercise<br>* Each child in this group will receive the selected physical therapy program which include mobility exercises, strengthening exercises, balance exercises, gait training exercises, and exercises to improve physical conditioning for one-hour session three times weekly for 8 successive weeks.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Improvement in Static balance of patients with ataxia after resection measured by center of pressure using force plate mode in the humac balance system. |  | 2 months | 
| Improvement in dynamic balance of patients with ataxia after resection measured by using tilt mode in the humac balance system. |  | 2 months | 
| Improvement in Activities of Daily Living (ADL) measured by functional independence measurement. |  | 2 months |