Effect of Water Rinsing After Topical Fluoride Application on Dental Plaque pH

Study Overview
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Brief Summary
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The aim of this study was to determine whether rinsing with water or cleansing teeth after topical fluoride therapy affect the dental plaque pH.

Official Title
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Effect of Water Rinsing After APF Application on Dental Plaque Acidogenicity

Conditions
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Dental Caries

Intervention / Treatment
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* Procedure: cleansing teeth after topical fluoride therapy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: healthy people (Without any systemic disease) normal unstimulated salivary rate Exclusion Criteria: Active dental caries taking any medication with any effect on saliva rate taking antibiotic (or antibacterial mouth rinses) during last 4 weeks usig fluoride mouth rinses during last 2 weeks.

Ages Eligible for Study
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Minimum Age: 21 Years
Maximum Age: 29 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: washing after 30 min<br>washing with water after 30 min following APF treatment | Procedure: cleansing teeth after topical fluoride therapy<br>* washing with water 0, 15 or 30 min after APF treatment or cleansing teeth with cotton roll immediately following APF treatment.<br>|
| Experimental: washing after 15 min<br>washing with water after 15 min following APF treatment | Procedure: cleansing teeth after topical fluoride therapy<br>* washing with water 0, 15 or 30 min after APF treatment or cleansing teeth with cotton roll immediately following APF treatment.<br>|
| Experimental: immediately washing with water<br>immediately washing with water after APF treatment | Procedure: cleansing teeth after topical fluoride therapy<br>* washing with water 0, 15 or 30 min after APF treatment or cleansing teeth with cotton roll immediately following APF treatment.<br>|
| Experimental: cleansing teeth with cotton roll<br>cleansing teeth with cotton roll immediately following APF treatment | Procedure: cleansing teeth after topical fluoride therapy<br>* washing with water 0, 15 or 30 min after APF treatment or cleansing teeth with cotton roll immediately following APF treatment.<br>|
| No Intervention: no fluoride therapy<br>control group | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| dental plaque PH |  | the pH of 48-hour dental plaque was measured using plaque sampling method before (baseline pH) and after sucrose challenge at 5, 10,15,20,30 minutes | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| maximum pH drop |  | 5,10,15,20 and 30 min after sucrose chalenge | 
| pH recovery time | time for returning to the baseline pH | within 30 min after sucrose challenge | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Acidogenicity, Acidulated phosphate fluoride, dental plaque, water rinsing