Long-Term Outcome Following Regenerative Periodontal Treatment of Intrabony Defects

Study Overview
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Brief Summary
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Many years ago, periodontal regenerative treatment has been done in Periodontics and Oral Medicine Clinic, Faculty of Dentistry, Mahidol University, Bangkok, Thailand. However, there is still lacking of study about long-term result of periodontal regenerative treatment of intrabony defects.

Detailed Description
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Beside, in the present, some materials for periodontal regenerative treatment are still expensive. Periodontists and patients have to plan together based on not only rationale of treatment but also cost and effectiveness. Thus the long-term result of treatment could be useful for the decision making.

Official Title
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Long-Term Outcome Following Regenerative Periodontal Treatment of Intrabony Defects: A Retrospective Study at Mahidol University

Conditions
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Regenerative Periodontal Treatment

Intervention / Treatment
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* Procedure: regeneration treated teeth loss
* Procedure: regenerated treated teeth with clinical attachment loss


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients who received regenerative therapy of the intrabony defects Patients who had the record of re-evaluation at 1 year post-surgery Exclusion Criteria: Patients who received regenerative therapy involving the furcation area Patients who received non-periodontal regenerative therapy Patients who received endodontic regeneration Patients who had an incomplete periodontal data recording
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| tooth loss<br>regeneration treated teeth loss | Procedure: regeneration treated teeth loss<br>* number of regeneration treated teeth loss<br>|
| clinical attachment loss ≥ 2 mm<br>regenerated treated teeth with clinical attachment loss ≥ 2 mm | Procedure: regenerated treated teeth with clinical attachment loss<br>* regenerated treated teeth with clinical attachment loss ≥ 2 mm<br>|
| clinical attachment loss loss < 2 mm<br>regenerated treated teeth with clinical attachment loss < 2 mm | Procedure: regenerated treated teeth with clinical attachment loss<br>* regenerated treated teeth with clinical attachment loss ≥ 2 mm<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Percentage of regenerative-treated tooth loss after periodontal regeneration | Percentage of regenerative-treated tooth loss since 1 year after periodontal regeneration until last visit of supportive periodontal treatment | 1 year | 
| Percentage of regenerative-treated sites with clinical attachment loss ≥ 2 mm | Percentage of regenerative-treated sites with clinical attachment loss ≥ 2 mm since 1 year after periodontal regeneration until last visit of supportive periodontal treatment | 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Variables (patient and tooth characteristics) that associated with tooth loss or clinical attachment loss | Patient variables and tooth characteristics associated with regenerative-treated tooth loss or sites with clinical attachment loss ≥ 2 mm from any supportive periodontal treatment visits (the last supportive periodontal treatment visit) compared to baseline or 1-year after surgery. | 1 year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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intrabony defect, periodontal regeneration