Central Executive Training and Parent Training for ADHD

Study Overview
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Brief Summary
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The goal of the current project is to combine two evidence- based treatments for school-aged children with ADHD: Central Executive Training (CET) and Behavioral Parent Training (BPT). CET is a computerized training intervention that improves ADHD symptoms and academic functioning by improving children's working memory abilities. BPT is a therapeutic intervention that improves family functioning and child oppositional-defiant (ODD) symptoms by changing parenting behaviors. Their combined use is expected to provide complementary and additive benefits, particularly if CET is delivered before BPT.

Official Title
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Evaluating the Efficacy of Sequenced Central Executive and Behavioral Parent Training for Children With ADHD

Conditions
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ADHD

Intervention / Treatment
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* Device: Central Executive Training (CET)
* Behavioral: Behavioral Parent Training (BPT)


Participation Criteria
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Eligibility Criteria
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Inclusion: Children ages 8-12 with principal ADHD diagnoses (via K-SADS); and parent AND teacher ratings in clinical/borderline range based on age and sex on ADHD Rating Scale (ADHD-5) or Behavior Assessment Scale for Children (BASC-3) Attention Problems/Hyperactivity subscales (i.e., 90th percentile or higher based on both informants). All DSM-5 ADHD presentations will be eligible. Exclusion: gross neurological, sensory, or motor impairment; history of seizure disorder, psychosis, bipolar, or severe dysregulation disorders that may interfere with participation (e.g., disruptive mood dysregulation, intermittent explosive, reactive attachment, substance use); intellectual disability or Wechsler Intelligence Scale for Children (WISC-V) short-form standard score <70; conditions requiring acute intervention, e.g., active suicidality; and non-English speaking child or parent.

Ages Eligible for Study
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Minimum Age: 8 Years
Maximum Age: 12 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: CET-then-BPT<br>Families receive CET in Phase 1 followed by BPT in Phase 2 | Device: Central Executive Training (CET)<br>* Central Executive Training (CET)<br>Behavioral: Behavioral Parent Training (BPT)<br>* Behavioral Parent Training (BPT)<br>|
| Experimental: BPT-then-CET<br>Families receive BPT in Phase 1 followed by CET in Phase 2 | Device: Central Executive Training (CET)<br>* Central Executive Training (CET)<br>Behavioral: Behavioral Parent Training (BPT)<br>* Behavioral Parent Training (BPT)<br>|
| Experimental: Waitlist then CET+BPT<br>Families do not receive either intervention in Phase 1 and then receive both CET and BPT concurrently in Phase 2 | Device: Central Executive Training (CET)<br>* Central Executive Training (CET)<br>Behavioral: Behavioral Parent Training (BPT)<br>* Behavioral Parent Training (BPT)<br>|
| Experimental: CET+BPT then 'waitlist' (follow-up)<br>Families receive CET and BPT concurrently in Phase 1, and then are followed in Phase 2 with not additional intervention | Device: Central Executive Training (CET)<br>* Central Executive Training (CET)<br>Behavioral: Behavioral Parent Training (BPT)<br>* Behavioral Parent Training (BPT)<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rapport visuospatial/phonological working memory test |  | Administered during a 3 hour post-treatment testing session occurring within 2 weeks of last intervention session | 
| Alabama parenting scale |  | Parent questionnaire requiring approximately 15 minutes to complete, administered to parent while child is completing the 3 hour post-treatment testing session occurring within 2 weeks of last intervention session | 
| Parenting sense of competence scale |  | Parent questionnaire requiring approximately 15 minutes to complete, administered to parent while child is completing the 3 hour post-treatment testing session occurring within 2 weeks of last intervention session | 
| Parent stress index |  | Parent questionnaire requiring approximately 15 minutes to complete, administered to parent while child is completing the 3 hour post-treatment testing session occurring within 2 weeks of last intervention session | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Behavior Assessment System for Children |  | Parent and teacher questionnaire requiring approximately 15 minutes to complete, administered to parent and mailed to teacher while child is completing the 3 hour post-treatment testing session occurring within 2 weeks of last intervention session | 
| ADHD Rating Scale |  | Parent and teacher questionnaire requiring approximately 15 minutes to complete, administered to parent and mailed to teacher while child is completing the 3 hour post-treatment testing session occurring within 2 weeks of last intervention session | 
| ODD symptoms (DSM-based checklist) |  | Parent and teacher questionnaire requiring approximately 15 minutes to complete, administered to parent and mailed to teacher while child is completing the 3 hour post-treatment testing session occurring within 2 weeks of last intervention session |