Swallowing Motor Function After Cervical Spine Surgery With Anterior Approach

Study Overview
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Brief Summary
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Dysphagia is a well-known complication following anterior cervical spine surgery. However, which muscle at oropharyngeal region weakness and the recovery course of these patients are still unknown. The ultrasonography was used to measure the oropharyngeal swallowing function. The high resolution impedance manometry (HRIM) could be used to measure the postoperative recovery esophageal function. we aimed to observe the changes and recovery course swallowing function parameters during the preoperative and postoperative period in the patients receiving anterior cervical spine surgery by HRIM and ultrasonography.

Detailed Description
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Dysphagia is a well-known complication following anterior cervical spine surgery. However, which muscle at oropharyngeal region weakness and the recovery course of these patients are still unknown. The ultrasonography was used to measure the oropharyngeal swallowing function. The high resolution impedance manometry (HRIM) could be used to measure the postoperative recovery esophageal function. We aimed to observe the changes and recovery course swallowing function parameters during the preoperative and postoperative period in the patients receiving anterior cervical spine surgery by HRIM and ultrasonography. Consecutive patients who will fulfill the criteria of cervical spine surgery patients under general anesthesia and aged >= 20 will be enrolled. The patients would receive the dysphagia questionnaire. All subjects would receive the swallowing function by ultrasonography and HRIM before the surgeries. The cough test was also measured. After the surgery, the patient would be followed the swallowing function in the postoperative one day, 1 week, and 1 months, 3 months (If needed) by HRIM and ultrasonography.

Official Title
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Evaluation of Changes of Swallowing Motor Function After Cervical Spine Surgery With Anterior Approach- the Implication of High Resolution Impedance Manometry

Conditions
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Patients Receiving Anterior Cervical Spine Surgery

Intervention / Treatment
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* Procedure: patients recieving anterior cervical spine surgery


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 1. Patients who fulfill the criteria of anterior cervical spine surgery under general anesthesia 2. Aged from 20-80 years old Exclusion Criteria: - 1. Major systemic disease, such as congestive heart failure, liver cirrhosis, end stage renal disease and malignancy. 2. Patients who have the risk of difficult ventilation or intubation. 3. pregnant women 4. coagulopathy

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patient receiving Anterior Cervical Spine Surgery<br>Patients who fulfill the criteria of anterior cervical spine surgery under general anesthesia Aged from 20-80 years old | Procedure: patients recieving anterior cervical spine surgery<br>* Anterior cervical discectomy with fusion, or ACDF, is a surgery designed to relieve spinal cord or nerve root pressure in the neck by removing all or part of a damaged disc<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| upper esophageal sphincter pressure changes | upper esophageal sphincter pressure changes measured by the HRIM | everage 1 month in the perioperative period | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| hyoid bone movement | the distance of hyoid bone movement measured by the ultrasonography | everage 1 month in the perioperative period |