Actigraphs for Detection of Asymmetries

Study Overview
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Brief Summary
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In hemiplegia quantitatively measurement of the asymmetry in the use of upper limbs could overcome the limitation of many outcome measures in which scores are dependent on the experience and training of the therapist. The main aim of this study was to determine the validity of Actigraph GXT3+ to measure asymmetry in the use of the two upper limbs during the Assisting Hand Assessment (AHA) in children, adolescents and young with hemiplegia aged 5-19 years, compared to age-matched typically developing subjects (TD).

Detailed Description
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This study aims to validate the use of Actigraphs as an evaluation tool of the upper limb asymmetry in children / adolescents and young adults with typical development or hemiplegia. The validation involves two stages: The first stage, carried out in the clinical setting, provides the use of Actigraphs (Actigraph GXT3+ and in a subgroup also FitBit) during the administration of clinical tests which are usually performed for the evaluation of the manual dominance in individuals with hemiplegia but also suitable for those with typical development. This first phase will allow to compare the quantitative measures acquired by the actigraphs (e.g. the mean activity of each hand and the asymmetry index i.e. difference between the mean activities of the two arms) with those from clinical standardized measures. The second phase, carried out in a non-clinical setting, provides the use of Actigraphs (Actigraph GXT3+ and in a subgroup also FitBit) in a subgroup of subject involved in the first phase for a week in order to measure the asymmetry index during the activities of daily living.

Official Title
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Detection of Asymmetries in Upper Limb Use Through Actigraphs

Conditions
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Hemiplegia, Hemiplegic Cerebral Palsy

Intervention / Treatment
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* Other: Actigraph


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age between 3-25 years Hemiplegia (experimental group) or Voluntary adhesion (control group) Exclusion Criteria: movement disorders sensory deficits

Ages Eligible for Study
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Minimum Age: 3 Years
Maximum Age: 25 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental group<br>Children, Adolescents and Young with hemiplegia | Other: Actigraph<br>* Actigraphs worn on wrists<br>|
| Control group<br>Children, Adolescents and Young with typical development | Other: Actigraph<br>* Actigraphs worn on wrists<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Correlation between Asymmetry Index (AI) and Assisting Hand Assessment (AHA) scores. | The asymmetry index (AI) is the difference between the mean activities of the dominant with those of the non dominant hand and it will be correlated with the scores of AHA. The AHA measures Upper Limb function during bimanual activities. The test evaluates spontaneous use of assisting hand during a semi-structured 10-15 minutes session with specific toys (Kids-AHA) or tasks (Ad-AHA) requiring bimanual handling. | Baseline | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Correlation between AI during AHA and AI in 7 days | Correlation of AI between a standardized bimanual test with 7 days of common daily life | Baseline- 1 week | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Upper limb, Inertial sensors