Evaluating the Endometrial Receptivity of FET Patient by Ultrasounicelastography

Study Overview
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Brief Summary
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Prospective clinical study ：observing the correlation between endometrial elasticity score, endometrial blood flow index (PI, RI, S/D, endometrial thickness, morphology) and clinical pregnancy rate. In order to find a non-invasive, convenient and comprehensive evaluation method of evaluating the endometrial receptivity, and to provide effective means for the frozen embryo transplantation patients to improving pregnancy outcome.

Detailed Description
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Randomly selecting 20-40 years patients were prepared to accept frozen embryo transplant ; HRT cycle preparation of endometrium；choosing HRT plan to prepare the transplantation endometrium.Establishing a strict standard of exclusion and exclude standard to exclude endometrial lesions and underlying disease.The patients were given elastography for 5-7 days afterEndometrium transformation.Observing the correlation between endometrial elasticity score, endometrial blood flow index (PI, RI, S/D, endometrial thickness, morphology) and clinical pregnancy rate. In order to find a non-invasive, convenient and comprehensive evaluation method of evaluating the endometrial receptivity, and to provide effective means for the frozen embryo transplantation patients to improving pregnancy outcome.

Official Title
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Evaluating the Endometrial Receptivity of FET Patients by Ultrasounicelastography and Predicting the Pregnancy Outcome.

Conditions
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Assisted Reproductive Technology, Ultrasonography

Intervention / Treatment
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* Other: Ultrasounicelastography


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: the volunteers voluntarily signed the informed consent. female patients between 20-40 years old. HRT cycle. no uterine cavity operation was performed within 3 months. Exclusion Criteria: endometrial polyps, abnormal uterine cavity, intrauterine adhesions and dysplasia of uterus. hydrosalpinx was not ligated. patients with uterine myoma and uterine fibroids;

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 40 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Intervention Model: Single Group Assignment
Interventional Model Description: Prospective study
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Ultrasounicelastography<br>Ultrasounicelastography:non-invasive, convenient and comprehensive evaluation method. | Other: Ultrasounicelastography<br>* Observing the correlation between endometrial elasticity score, endometrial blood flow index (PI, RI, S/D, endometrial thickness, morphology) and clinical pregnancy rate.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| endometrial receptivity | Observing the correlation between elasticity score, endometrial blood flow index (PI, RI, S/D, endometrial thickness, morphology) and clinical pregnancy rate. | Month 12 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Ultrasounicelastography, Frozen embryo transplantation, Endometrial Receptivity, pregnancy outcome