Lung Surgery With Enhanced Recovery VS. Lung Surgery Without Enhanced Recovery

Study Overview
=================
Brief Summary
-----------------
Objective: The adoption of Enhanced Recovery Surgery programs in lung resection is relatively recent with limited outcome data. This study aimed to determine the impact of an Enhanced Recovery Surgery pathway on short- term and long- term results in patients undergoing lung resection for primary lung cancer. Methods: A Randomized Controlled Trial was designed to collect the perioperative data on consecutive patients undergoing lung resection for primary lung cancer. Patients will be randomizely assigned to the ERAS- Group and Control- Group. Short-term and long- term effect will be compared between the two groups.

Official Title
-----------------
The Short Term and Long Term Comparison of Lung Surgery With or Without Enhanced Recovery

Conditions
-----------------
Lung Cancer, Surgery, ERAS

Intervention / Treatment
-----------------
* Procedure: Enhanced Recovery After Surgery (ERAS )
* Procedure: Traditional perioperative management without Enhanced Recovery After Surgery (ERAS )


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients with stage I-IIIa Non-small-cell Lung Cancer underwent radical resection or other benign lung lesions need VATS surgery. - Exclusion Criteria: cardio-pulmonary function couldn't tolerate surgery -

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: ERAS- Group<br>Patients underwent surgery for lung cancer accepted the enhanced recovery after surgery (ERAS). | Procedure: Enhanced Recovery After Surgery (ERAS )<br>* the treatment of procedure according to Guidelines for enhanced recovery after lung surgery: recommendations of the ERAS Society and the ESTS<br>|
| Other: Control- Group<br>Patients underwent surgery for lung cancer without enhanced recovery after surgery (ERAS). | Procedure: Traditional perioperative management without Enhanced Recovery After Surgery (ERAS )<br>* the treatment of procedure not abiding Guidelines for enhanced recovery after lung surgery<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| intensive care unit utilization | the time in intensive care unit utilization | within 4 days after surgery | 
| the degree of pain | Visual Analogue Scale/Score | within 4 days after surgery | 
| the time of ambulation | the time after surgery that patients could leave the bed and walk | within 48 hours after surgery | 
| the time for oral feed | the time for oral feed | within 48 hours after surgery | 
| the time of hospitalization | the time of hospitalization | within 5 days after surgery | 
| complications | the rate of complications | within 7 days after surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| disease- free survival | disease- free survival | within 5 years after surgery | 
| overall survival | overall survival | within 10 years after surgery |