Perioperative Risk Factors for Postoperative Delirium in Children

Study Overview
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Brief Summary
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Despite recent advances in postoperative delirium research, the proportion of children with postoperative delirium is still high. Although postoperative delirium is a frequent complication and is associated with the need for more inpatient hospital care and longer length of hospital stay, little is known about risk factors for recovery room delirium (RRD) occurred in postanaesthesia care unit. The aim of the study was to determine pre- and intraoperative risk factors for the development of RRD among children undergoing non cardiovascular surgery.

Detailed Description
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Recovery room delirium (RRD) defined as delirium occurred in PACU was diagnosed according to RASS-PAEDS criteria. Pre-, intra-, and postoperative data of patients undergoing elective non cardiovascular surgery were prospectively collected, univariate and multivariate logistic regression were performed to find the risk factors related to postoperative delirium.

Official Title
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Perioperative Risk Factors for Postoperative Delirium in Children Following General Anesthesia

Conditions
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Delirium, Postoperative

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: between 3 to 12 years old elective non-cardiovascular surgery general anesthesia Exclusion Criteria: under regional anaesthesia instable vital sign without consent form underwent neurosurgery history of primary neurologic diseases stayed less than 10min in PACU received general anaesthesia but recovered in locations outside the recovery room

Ages Eligible for Study
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Minimum Age: 3 Years
Maximum Age: 12 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Delirium<br>Delirium was determined by RASS-PAEDS | |
| no Delirium<br>no Delirium was determined by RASS-PAEDS | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The presence of delirium in post anesthesia care unit (PACU) and in ward determined by RASS-PAEDS criteria |  | at 1, 8, 16, 24, 48 and 72 postoperative hour | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Maximal and minimal heart rate in PACU |  | every 15 min during PACU stay | 
| Pulse Oximeter Oxygen Saturation (SpO2) in PACU |  | every 15 min during PACU stay | 
| Hospital-length of stay |  | before discharge | 
| Total health care fees |  | during hospital stay | 
| Quality of recovery measured by PACBIS criteria |  | at 1, 8, 16, 24, 48 and 72 postoperative hour | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Delirium, Postoperative, Non-cardiovascular surgery, Post-anaesthesia care unit, patients between 3 to 12 years old, undergoing selective non-cardiac surgery, under general anesthesia, surgery, general anesthesia