Online Exercise Intervention for Psychosis Patients Receiving Residential Care

Study Overview
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Brief Summary
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The main objective of this randomised controlled trial (RCT) is to investigate the immediate and long-term effectiveness of 8-week online exercise intervention for people with psychosis receiving residential care.

Detailed Description
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The effect will also be evaluated after 6-month and 12-month, anticipate seeing the maintenance of physical activity throughout a year of time. The secondary objective of this RCT is to investigate if the exercise intervention will be effective in improving the clinical symptoms, cognitive functioning and social functioning of the subjects, and to see if the improvement can be maintained (or improve) over a longer period of time (i.e., 6-month and 12-month).

Official Title
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A Randomised Controlled Trial of Online Exercise Intervention for Psychosis Patients Receiving Residential Care in Hong Kong

Conditions
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Psychosis

Intervention / Treatment
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* Behavioral: Online exercise
* Behavioral: SMS message


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Based on the Fifth version of the Diagnostic and Statistical Manual of Mental Disorders diagnosis to have schizophrenia and related psychotic disorders Have the ability to understand Chinese Able to give informed consent Exclusion Criteria: Severe physical illness (Myocardial Infarction, Hypertension, Fracture, Spinal problems in which exercise may be contraindicated), and seizure disorders. Comorbid substance dependence Unstable psychotic symptoms Any history of brain trauma or organic brain disease Known history of intellectual disability or special school attendance Other mental conditions that requires other treatment priorities, e.g., suicidal risk. Other medical conditions that severely limits participation, comprehension, or adherence to the treatment or assessment e.g., epilepsy, dementia, terminal medical illness.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 69 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Online exercise<br>SMS messages on encouraging active lifestyle plus an online exercise video | Behavioral: Online exercise<br>* SMS messeages on encouraging active lifestyle and online exercise video will be sent to the participant weekly for 8 weeks.<br>|
| Active Comparator: SMS message<br>SMS messages on encouraging active lifestyle | Behavioral: SMS message<br>* SMS messeages on encouraging active lifestyle will be sent to the participant weekly for 8 weeks.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Exercise level | Measured by the International Physical Activity Questionnaire, a higher MET calculated from the scale indicates a higher exercise level | 6 months and 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Severity of psychotic symptoms | Measured by the Positive and Negative Syndrome Scale, a higher score indicates a more severe level of psychotic symptoms | 6 and 12 months |