Transversalis Fascia Plane Block and Rectus Sheath Block in Renal Transplantation Donors

Study Overview
=================
Brief Summary
-----------------
Transversalis fascia plane block (TFPB) is a relatively new, easy-to-apply and safe regional anesthesia technique used to provide postoperative analgesia in various surgeries. It has been shown that TFPB and rectus sheath block (RSB) administration reduces opioid consumption and related side effects in patients undergoing surgery with general anesthesia. To our knowledge, there is no study examining TFPB in donor nephrectomy. The investigators aimed to prospectively examine the effect of TFPB and RSB on opioid consumption in postoperative period on donors who will undergo laparoscopic nephrectomy in renal transplantation surgery.

Official Title
-----------------
Effects of Transversalis Fascia Plane Block and Rectus Sheath Block on Opioid Consumption in Renal Transplantation Donors

Conditions
-----------------
Postoperative Pain

Intervention / Treatment
-----------------
* Procedure: Transversalis fascia plane block and rectus sheath block
* Device: Intravenous fentanyl patient control device


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Donor patients scheduled for elective nephrectomy in renal transplantation surgery American Society of Anesthesiologists (ASA) I-II Patients who are aged between 18-75 Exclusion Criteria: Skin infection at the block area Coagulation disorder and using anticoagulant drugs End-stage organ and system failure Severe pulmonary and/or cardiovascular problems Substance addiction or known psychiatric or mental problems Chronic painkiller usage

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Transversalis Fascia Plane Block and Rectus Sheath Block Group<br>Transversalis Fascia Plane Block and Rectus Sheath Block will be administered to this group. | Procedure: Transversalis fascia plane block and rectus sheath block<br>* Transversalis fascia plane block and rectus sheath block will be administered after the surgery.<br>Device: Intravenous fentanyl patient control device<br>* 24-hour fentanyl consumption will be recorded.<br>|
| Sham Comparator: Control Group<br>No regional anesthesia technique will be applied to the control group. | Device: Intravenous fentanyl patient control device<br>* 24-hour fentanyl consumption will be recorded.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Total opioid consumption retrieved from patient records | the amount of fentanyl required by the patient and given by the device will be recorded for the first 24 hours. | up to 24 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Numeric Rating Scale (NRS) | Pain of patients will be evaluated and recorded according to NRS. A NRS requires the patient to rate their pain on a defined scale between 0 and10 (0 is no pain and 10 is the worst pain) | up to 24 hours |