Collecting Blood and Tissue Samples From Family Members of Patients With Pancreatic Diseases, Pancreatic Cancer, and Melanoma

Study Overview
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Brief Summary
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RATIONALE: Collecting and storing samples of blood and tissue from family members of patients with cancer to test in the laboratory may help the study of cancer in the future. PURPOSE: This clinical trial is collecting blood and tissue samples from family members of patients with pancreatic disease, pancreatic cancer, and melanoma.

Detailed Description
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OBJECTIVES: To collect clinical history, family history, and blood and/or tissue samples from family members of patients diagnosed with pancreatic diseases, pancreatic cancer, or melanoma. To learn whether inherited factors increase the risk of pancreatic diseases, pancreatic cancer, or other cancers. OUTLINE: Study participants undergo collection of blood and/or tissue samples as well as survey data for inclusion in a familial data and tissue registry. Participants complete two baseline surveys regarding their personal, family, health, and environmental exposure histories and regarding their opinions on cancer and cancer screening. Patients also complete a follow-up survey at 1 year and undergo review of their medical records.

Official Title
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Biospecimen Resource for Familial Pancreas Research, a Data and Tissue Registry (Also Known as a Bio-repository, Bio-bank, Data and Tissue Database, Data and Tissue Bank, Etc.) to Help Advance Research in Familial Pancreas Disease

Conditions
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Familial Pancreatic Cancer

Intervention / Treatment
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* Other: biologic sample preservation procedure
* Other: medical chart review
* Other: survey administration


Participation Criteria
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Eligibility Criteria
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DISEASE CHARACTERISTICS: Meets 1 of the following criteria: Has at least 2 blood relatives with pancreatic cancer (both must be related) Has at least 1 blood relative with pancreatic cancer and 1 with melanoma (both must be related) PATIENT CHARACTERISTICS: Mentally competent and able to provide informed consent Able to understand and read English PRIOR CONCURRENT THERAPY: Not specified

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 120 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: biologic sample preservation procedure|one blood sample|
|Other: medical chart review|confirmation of cancer diagnosis|
|Other: survey administration|at baseline enrollment and 12 months post-enrollment|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Collection of familial data and biospecimens in a data and tissue repository for familial pancreas research |  | baseline | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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family, history, pancreas, cancer, melanoma, genetic