Visual Performance of New Apodized Diffractive Multifocal IOL With Addition of Plus Three

Study Overview
=================
Brief Summary
-----------------
The purpose of the study is to determine whether implantation of a multifocal IOL with a modified addition at lens plane(Restor +3) results in better intermediate visual acuity with similar performance at distance and near compared to other multifocal IOL with similar design but with higher addition at lens plane. Patient's contrast sensitivity of vision and best reading distance following Restor +3 implantation were also assessed. Study hypothesis: the implantation of an intraocular lens (IOL) with a modified addition at lens plane (restor +3, Alcon Laboratories,Inc) results in better intermediate visual acuity with similar distance and near visual acuity after cataract surgery.

Detailed Description
-----------------
Patients with bilateral visually significant cataract with corneal astigmatism lower than 1.0D (diopters) will be eligible for inclusion in the study. Exclusion criteria will be any ocular diseases, such as corneal opacities or irregularity, dry eye, amblyopia, anisometropia, glaucoma, retinal abnormalities, surgical complications, IOL tilt, IOL decentration greater than 0.4 mm (estimated by retroillumination), or incomplete follow-up. Patients will be examined before surgery and at 1, 7, 30, 90 days and 3and 6 months after surgery.

Conditions
-----------------
To Study the Influence of an Multifocal Intraocular Lens With Different Addition on Intermediate Visual Acuity

Intervention / Treatment
-----------------
* Other: Implantation of a multifocal Intraocular lens


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: •Patients with bilateral visually significant cataract with corneal astigmatism lower than 1.0D (diopters) Exclusion Criteria: Ocular diseases, such as corneal opacities or irregularity, dry eye amblyopia, anisometropia, glaucoma, retinal abnormalities Surgical complications Intraocular lens (IOL) tilt, IOL decentration greater than 0.4 mm (estimated by retroillumination) Incomplete follow-up.

Ages Eligible for Study
-----------------
Minimum Age: 40 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Restor +3<br>patients will be implanted bilaterally with Restor + 3 | Other: Implantation of a multifocal Intraocular lens<br>* Bilateral implantation of a multifocal IOl<br>* Other names: Restor + 4 SN6AD3;|
| restor +4<br>Patients will be implanted bilaterally with Restor +4 | Other: Implantation of a multifocal Intraocular lens<br>* Bilateral implantation of a multifocal IOl<br>* Other names: Restor + 4 SN6AD3;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| distance,intermediate and near visual acuity |  | 1, 3 and 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| reading speed and contrast sensitivity |  | 6 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
multifocal intraocular lens, visual acuity, presbiopia