Effects of Obesity on Rectus Femoris Muscle Thickness, Sarcopenia, Gait and Balance in Women

Study Overview
=================
Brief Summary
-----------------
Research; It is a planned, non-invasive, controlled study in obese female volunteers and non-obese female volunteers. The population of the study consists of voluntarily non-obese women and obese women. Sarcopenia assets of individuals will be measured with the sarc-f questionnaire, and then muscle strength, muscle mass and physical performance tests will be measured. Then, rectus femoris muscle thickness will be measured with USG, and then walking and balance will be measured with ZEBRIS.

Official Title
-----------------
Effects of Obesity on Rectus Femoris Muscle Thickness, Sarcopenia, Gait and Balance in Women

Conditions
-----------------
Sarcopenic Obesity, Sarcopenia, Obesity

Intervention / Treatment
-----------------
* Diagnostic Test: Ultrasonografi, Sarcopenia measurement, Zebris


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Being over 18 years old and female Volunteering and accepting to participate in the study BMI 30-39.9 kg/m2 in obese women (experimental group) BMI 18-27.9 kg/m2 in non-obese women (control group) Not having cardiorespiratory, neurological, orthopedic and metabolic disorders Exclusion Criteria: Being under 18 years old and male Having a BMI of 40.0 kg/m2 and above in obese women (experimental group) BMI 28.0 kg/m2 and above in non-obese women (control group) Having cardiorespiratory, neurological, orthopedic and metabolic disorders

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| non-obese women<br>After obtaining demographic information for women with a BMI of 18-27.9 kg/m2 for at least 6 months, Body Mass Index (BMI) will be calculated and the relationship between rectus femoris muscle thickness, sarcopenia, gait and balance will be evaluated and will be compared with obese group. | Diagnostic Test: Ultrasonografi, Sarcopenia measurement, Zebris<br>* The rectus femoris muscle thickness of the participants will be performed in B mode via USG (Mindray-UMT 200,USA) with a multifrequency (7-15 MHz) linear probe and the measurement will be reported. TANITA for sarcopenia, hand grip strength and walking speed will be evaluated. Gait time-distance parameters and Static balance COP parameters (COP speed (cm/s) and COP length (cm)) will be recorded using Zebris™ FDM-2.<br>|
| obese women<br>After obtaining demographic information in women with a BMI of 30-39.9 kg/m2, Body Mass Index (BMI) will be calculated and the relationship between obesity and rectus femoris muscle thickness, sarcopenia, gait and balance will be evaluated. | Diagnostic Test: Ultrasonografi, Sarcopenia measurement, Zebris<br>* The rectus femoris muscle thickness of the participants will be performed in B mode via USG (Mindray-UMT 200,USA) with a multifrequency (7-15 MHz) linear probe and the measurement will be reported. TANITA for sarcopenia, hand grip strength and walking speed will be evaluated. Gait time-distance parameters and Static balance COP parameters (COP speed (cm/s) and COP length (cm)) will be recorded using Zebris™ FDM-2.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rectus femoris muscle thickness | Measurement of muscle thickness with ultrasound | baseline |