Use of Perfusion Index Change as a Predictor of Hypotension During Propofol Sedation in Adult Patients Undergoing Hip Surgery Under Spinal Anesthesia: A Prospective Observational Study

Study Overview
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Brief Summary
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This observational study is to evaluate Perfusion Index Change as a Predictor of Hypotension During Propofol Sedation in Adult Patients Undergoing Hip Surgery Under Spinal Anesthesia.

Official Title
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Use of Perfusion Index Change as a Predictor of Hypotension During Propofol Sedation in Adult Patients Undergoing Hip Surgery Under Spinal Anesthesia: A Prospective Observational Study

Conditions
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Hypotension, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use

Intervention / Treatment
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* Other: Observation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adult patients having hip surgery under spinal anesthesia and propofol sedation Exclusion Criteria: ASA class IV or above pregnancy inability to measure noninvasive blood pressure on the arm preexisting hemodynamic instability known peripheral artery occlusive disease known autonomic nerve dysfunction uncontrolled hypertension

Ages Eligible for Study
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Minimum Age: 19 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Propofol sedation after SA<br>Participants who undergo propofol sedation after spinal anesthesia | Other: Observation<br>* no intervention<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 5-minute perfusion index change | ability of perfusion index change 5 minutes after induction in predicting propofol sedation-induced hypotension (perfusion index change is calculated as the percent change from baseline values) | After sedation until start of surgery (an average of 20 minutes) | 
| 10-minute perfusion index change | ability of perfusion index change 10 minutes after induction in predicting propofol sedation-induced hypotension (perfusion index change is calculated as the percent change from baseline values) | After sedation until start of surgery (an average of 20 minutes) | 
| baseline perfusion index | ability of baseline perfusion index in predicting propofol sedation-induced hypotension | After sedation until start of surgery (an average of 20 minutes) | 
| 5-minute perfusion index | ability of perfusion index 5 minutes after induction in predicting propofol sedation-induced hypotension | After sedation until start of surgery (an average of 20 minutes) | 
| 10-minute perfusion index | ability of perfusion index 10 minutes after induction in predicting propofol sedation-induced hypotension | After sedation until start of surgery (an average of 20 minutes) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 5-minute perfusion index change difference | difference of perfusion index change 5 minutes after induction between participants who do or do not develop hypotension during propofol sedation after spinal anesthesia (perfusion index change is calculated as the percent change from baseline values) | After sedation until start of surgery (an average of 20 minutes) | 
| 10-minute perfusion index change difference | difference of perfusion index change 10 minutes after induction between participants who do or do not develop hypotension during propofol sedation after spinal anesthesia (perfusion index change is calculated as the percent change from baseline values) | After sedation until start of surgery (an average of 20 minutes) | 
| baseline perfusion index difference | difference of baseline perfusion index between participants who do or do not develop hypotension during propofol sedation after spinal anesthesia | After sedation until start of surgery (an average of 20 minutes) | 
| 5-minute perfusion index difference | difference of perfusion index after 5 minutes of induction between participants who do or do not develop hypotension during propofol sedation after spinal anesthesia | After sedation until start of surgery (an average of 20 minutes) | 
| 10-minute perfusion index difference | difference of perfusion index after 10 minutes of induction between participants who do or do not develop hypotension during propofol sedation after spinal anesthesia | After sedation until start of surgery (an average of 20 minutes) |