Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation

Study Overview
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Brief Summary
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The hypothesis of this study is Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation (NAD-CPR) would improve survival of out-of-hospital cardiac arrest (OHCA).

Detailed Description
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Out-of-hospital cardiac arrest (OHCA) is a major health problem, occurring in about 1 in 1,500 adults in the developed countries each year. Although layperson CPR and defibrillation are crucial components of chain of survival, layperson CPR rate and it's quality is low and public-access defibrillation (PAD) program is not cost-effective.If trained bystanders can know the information of occurrence of OHCA and nearest place for automated external defibrillator (AED) at the same time by dispatch center, these neighborhoods could run and give high quality CPR and early defibrillation. If this protocol ,Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation(NAD-CPR), is introduced to community, it may improve survival of OHCA.

Official Title
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Population Based Intervention Trial of Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation

Conditions
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Out of Hospital Cardiac Arrest

Intervention / Treatment
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* Other: NAD-CPR


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: all OHCA with presumed cardiac etiology more than 15 years old assessed by emergency medical service (EMS) providers dispatched by dispatch center dispatcher detected OHCA patients Exclusion Criteria: OHCA with non-cardiac etiology prolonged cardiac arrest with a suspected duration more than 30 minutes cases with rigor mortis or rivor mortis, decapitated or decomposed body Non detected cases by dispatcher

Ages Eligible for Study
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Minimum Age: 15 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: NAD-CPR<br>When dispatcher detects a patient with OHCA, the dispatcher activates trained neighborhoods by informing events nearby using short message service via cellular phone. The neighborhood within geographically accessible area who could perform effective CPR and defibrillation would be alerted with event of OHCA and the nearest AED. | Other: NAD-CPR<br>* When Dispatcher detects OHCA, short message service (SMS)about the OHCA event and information about the location of nearest AED is sent to trained laypersons within geographically accessible area.<br>|
| No Intervention: Conventional dispatcher assisted CPR<br>When dispatcher detects OHCA, they instruct the caller with CPR instructions. This is conventional dispatcher assisted CPR performed in Seoul. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of Participants Surviving at Hospital Discharge | we compared the survival to discharge rate between before intervention period and intervention period. Survival to discharge checked at the discharge point of hospital. | discharge time from first admission from emergency department within 2 month | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of Participants With Pre-Hospital Return of Spontaneous Circulation (ROSC) | we compared the Pre-hospital return of spontaneous circulation (ROSC) rate between before intervention period and intervention period. | hospital arriving time from ambulance within 2 hours | 
| Number of Participants With Good Neurological Recovery | Cerebral performance category 1 or 2 is defined as good neurological recovery. we compared the good neurological recovery rate between before intervention period and intervention period. | discharge time from first admission from emergency department within 2 month | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Out of Hospital Cardiac Arrest, Cardiopulmonary Resuscitation, dispatch, emergency medicine