Artificial Intelligence-based Mortality Prediction Among Cancer Patients in the Hospice Ward

Study Overview
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Brief Summary
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The purpose of this study is to develop a novel deep-learning-based survival prediction model employing patient activity data recorded by a wearable device.

Detailed Description
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This study aims to develop a deep-learning-based survival prediction model that utilizes patient movement data upon admission to predict their clinical outcomes: either death or discharge with stable condition. Objective data of the patients are recorded by a wearable device and documented as parameters of physical activity, angle, and spin. In addition to objective data, the investigators also document patients' Karnofsky Performance Status assessed subjectively by clinical doctors. Finally, the investigators aim to explore and describe the applicability, potential, and limitations of the survival prediction model based on patient movement data as a simple prognostic parameter in clinical settings.

Official Title
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Artificial Intelligence-based Activity Recognition and Mortality Prediction Using Circadian Rhythm, Among Cancer Patients in the Hospice Ward

Conditions
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End Stage Cancer

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Participants aged 20 years or older admitted to the hospice care unit at Taipei Medical University Hospital Participants diagnosed with at least one end-stage solid tumor diseases Participants consented to receive hospice care Exclusion Criteria: Participants aged below 20 years of age Participants diagnosed with leukemia or carcinoma of unknown primary Participants with evident signs of approaching death upon admission Participants with no vital signs upon admission Participants who continued to receive aggressive treatment despite admission to the hospice care unit

Ages Eligible for Study
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Minimum Age: 20 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Specificity and Sensitivity of using Artificial Intelligence based models for prediction of Clinical Outcomes of End-stage Cancer Patients using actigraphy data | The primary outcome of the study will be to evaluate whether the analysis of the movement data captured using actigraphy device can help to predict clinical outcomes either deceased or discharged alive from hospital, with a high specificity and sensitivity, using Artificial Intelligence based prediction modelling. | From date of admission to hospice ward until the date of first documented discharge from hospital or date of death from any cause, whichever came first, assessed up to 1 month | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Wearable Device, Actigraphy Device, Survival Prediction, Deep Learning, Artificial Intelligence, Hospice Care, Palliative Care