Oxygen Consumption in Adolescent Idiopathic Scoliosis

Study Overview
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Brief Summary
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Adolescent Idiopathic Scoliosis (AIS) is a rotational deformity of the spine that could be seen 2-3% of population. Conservative treatment of AIS with 20-45 degree lateral flexion angle (Cobb) includes brace and therapeutic exercises. Some gait abnormalities were defined like decreased torsional movements of spine, increased muscular work and energy expenditure in AIS. Additionally wearing a brace limits pelvic motions and affects pendulum-like mechanism of gait. Our aim was to investigate gait energy consumption, pulmonary functions, balance and lower extremity loading symmetry in AIS subjects who are getting conservative treatment.

Official Title
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Effect of Conservative Treatment on Pulmonary Functions, Gait Oxygen Consumption Balance and Lower Limb Load Distribution in Adolescents With Idiopathic Scoliosis

Conditions
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Adolescent Idiopathic Scoliosis

Intervention / Treatment
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* Device: Rigid Thermoplastic Spinal Brace


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Cobb angle between 20-45 degree, Prescribed a rigid spinal brace by doctor Exclusion Criteria: Having leg length discrepancy more than 1 centimeter Having a lung disease Having another orthopedic or neurologic disorder

Ages Eligible for Study
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Minimum Age: 10 Years
Maximum Age: 16 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Adolescent Idiopathic Scoliosis<br>Subjects with AIS who are beginning to the conservative treatment. | Device: Rigid Thermoplastic Spinal Brace<br>* Custom made rigid thermoplastic brace with 23 hours daily wearing time.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Gait Oxygen Consumption | Oxygen consumption will be assessed with a mobile metabolic analyzer during walking on treadmill with 4 km/h gait speed. Recordings will be taken for 2 minutes after first 2 minutes of walking. | Assessment will be done at the end of first month of conservative treatment. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pulmonary Functions | Forced vital capacity (FVC), Forced expiratory volume in one second (FEV1), FEV1/FVC ratio, peak expiratory flow (PEF), forced expiratory flow at 25-75 % of the pulmonary volume (FEF 25-75%) will be assessed with spirometer. | Assessment will be done at the end of first month of conservative treatment. | 
| Balance | Balance will be assessed with a special equipment that gives deviation that lower values mean better. | Assessment will be done at the end of first month of conservative treatment. | 
| Lower extremity loading symmetry | Plantar loading symmetry will be assessed with a pedobarograph located in the middle of a six meters walking way. Loading symmetry will be calculated and compared as percentage of total pressure. | Assessment will be done at the end of first month of conservative treatment. |