Cardiovascular Risk in Toledo Population

Study Overview
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Brief Summary
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This epidemiological and observational study is aimed to assess cardiovascular risk (CVR) by investigating the prevalence of CVR factors (CVRF), target organ damage (TOD) and cardiovascular disease (CVD) in general population of the sanitary area of Toledo.

Detailed Description
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Epidemiological and observational study that is analyzing a sample from the general population aged 18 years or older, randomly selected from a database of sanitary cards stratified by age and gender. Clinical history, physical examination and complementary tests are being performed. Total blood and serum samples are being frozen (-85ºC) for future genetic studies. The biobank is currently being registered at the Virgen de la Salud hospital of Toledo. CVR is assessed by SCORE scale calibrated for Spanish population and the Framingham Heart Study scale. Patients will be periodically visited, with a minimum follow-up of 5 years. Standard statistical analysis will be performed.

Official Title
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RIesgo CARdiovascular y Eventos Cardiovasculares en la población General Del área Sanitaria de TOledo

Conditions
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Cardiovascular Risk Factor, Cardiovascular Diseases

Intervention / Treatment
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* Other: Observational


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Subjects aged 18 years or older, randomly selected from a database of health cards stratified by age and gender Exclusion Criteria: Individulas aged under 18 years. Subjects who do not sign the informed consent. Subjects that due to different conditions (physical, mental or social) is expected that do not complete the expected follow-up.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Cohort of the study<br>A sample from the general population aged 18 years or older, randomly selected from a database of sanitary cards stratified by age and gender. | Other: Observational<br>* This is an observational study. No specific diagnostic or therapeutic procedure will be performed due to the study.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Assess cardiovascular risk of the study population | Cardiovascular risk will be determined according to SCORE scale calibrated for Spanish population and the Framingham Heart Study scale. | December 2020 | 
| Prevalence of cardiovascular risk factors | To assess the prevalence of cardiovascular risk factors | December 2020 | 
| Prevalence of cardiovascular disease | To assess the prevalence of cardiovascular disease | December 2020 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Hypertension, Diabetes, Dyslipidemia, Smoking, Cardiovascular, Toledo