SAS-J Compared to OAGB and LSG as a Treatment for Morbid Obesity

Study Overview
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Brief Summary
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150 morbidly obese patients divided into to equal groups, group A underwent single anastomosis sleeve jejunal bypass and group B underwent mini gastric bypass, group C underwent sleeve gastrectomy. All patients were followed for at least one year. all cases were evaluated as regard BMI, complications, nutritional status and obesity-related comorbidities.

Detailed Description
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150 morbidly obese patients divided into to equal groups, group A underwent single anastomosis sleeve jejunal bypass and group B underwent mini gastric bypass, group C underwent sleeve gastrectomy. All patients were followed for at least one year. all cases were evaluated as regard BMI, complications, nutritional status and obesity-related comorbidities. the minimal follow up period is one year

Official Title
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Single Anastomosis Sleeve Jejunal Bypass Compared to One Anastomosis Gastric Bypass and Sleeve Gastrectomy as a Treatment for Morbid Obesity

Conditions
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Morbid Obesity

Intervention / Treatment
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* Procedure: SAS-JB
* Procedure: OAGB
* Procedure: LSG


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: obese patients with BMI more than 40 with or without co-morbidity or more than 35 with co-morbidity patients fit for laparoscopic surgery give approval to share in the study Exclusion Criteria: patients refused to share in the study patients unfit for surgery patients aged less than 18 and older than 60 patient with previous upper abdominal surgery either for obesity or other diseases revisional bariatric procedures

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: SAS-JB<br>laparoscopic single anastomosis sleeve jejunal bypass | Procedure: SAS-JB<br>* single anastomosis sleeve jejunal bypass<br>|
| Active Comparator: MGB<br>laparoscopic mini gastric bypass | Procedure: OAGB<br>* one anastomosis gastric bypass<br>|
| Active Comparator: LSG<br>laparoscopic sleeve gastrectomy | Procedure: LSG<br>* laproscopic sleeve gastrectomy<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| percentage of excess weight loss | percentage of excess weight loss in kilogram | 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the incidence of nutritional deficiency | the incidence of nutritional deficiency like anemia, hypocalcamia, hypoproteinemia. | 2 years | 
| the rate of improved co morbidity | the effect of the operation on co morbidity like diabetes and hypertension | 2 years | 
| the incidence of early operative complications | early operative complications like leak, bleeding | one month |