Evaluation of Emotional Status and Coronary Flow Characteristics by TIMI Frame Count Method

Study Overview
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Brief Summary
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This study evaluates the effects of emotional status on coronary flow in patients undergoing elective coronary angiography. Patients whom undergoing elective coronary angiography will fulfill the Beck Anxiety Inventory, Beck Depression Inventory, State-Trait Anxiety Inventory, Hospital Anxiety and Depression Scale. State Anxiety Inventory will be fulfilled both before the intervention and after 1 hour the patients learned the results of the coronary angiography. The other scales will be performed after 1 hour the patients learned their results. Coronary flow will be assessed by TIMI (Thrombolysis In Myocardial Infarction) frame count method.

Official Title
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Effects of Emotional Status on Coronary Flow in Patients Undergoing Coronary Angiography:Multicenter TIMI Frame Count Assessment Study (STRAIN-TIMI Study)

Conditions
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Coronary Artery Disease, Coronary Artery Ectasia, Slow-Flow Phenomenon, Endothelial Dysfunction, Anxiety, Depression

Intervention / Treatment
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* Procedure: coronary angiography


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients whom planned elective coronary angiography and accept to be included in the study as a participant Exclusion Criteria: < 18 years, history of prior coronary angiography, history of coronary artery revascularization, acute coronary syndrome patients, atrial fibrillation, heart failure, known systemic diseases

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: normal coronary anatomy<br>coronary angiography will be performed by transfemoral or transradial route. | Procedure: coronary angiography<br>* Coronary angiography will be performed by transfemoral or transradial approach in all patients. In order to evaluate each coronary artery, at least four views from the left and two views from the right system will be taken.<br>|
| Active Comparator: coronary artery ectasia<br>coronary angiography will be performed by transfemoral or transradial route. | Procedure: coronary angiography<br>* Coronary angiography will be performed by transfemoral or transradial approach in all patients. In order to evaluate each coronary artery, at least four views from the left and two views from the right system will be taken.<br>|
| Active Comparator: slow coronary flow<br>coronary angiography will be performed by transfemoral or transradial route. | Procedure: coronary angiography<br>* Coronary angiography will be performed by transfemoral or transradial approach in all patients. In order to evaluate each coronary artery, at least four views from the left and two views from the right system will be taken.<br>|
| Active Comparator: nonobstructive coronary artery disease<br>coronary angiography will be performed by transfemoral or transradial route. | Procedure: coronary angiography<br>* Coronary angiography will be performed by transfemoral or transradial approach in all patients. In order to evaluate each coronary artery, at least four views from the left and two views from the right system will be taken.<br>|
| Active Comparator: obstructive coronary artery disease<br>coronary angiography will be performed by transfemoral or transradial route. | Procedure: coronary angiography<br>* Coronary angiography will be performed by transfemoral or transradial approach in all patients. In order to evaluate each coronary artery, at least four views from the left and two views from the right system will be taken.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| TIMI frame count method analysis |  | 1 day |