Cataract Surgery In Patients With Advanced Age

Study Overview
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Brief Summary
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This study evaluates and compares clinical outcomes of < 85 and ≥ 85 year old patients who underwent cataract surgeries.

Detailed Description
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The medical records of patients who were underwent cataract surgery between January 2014 and October 2017 were investigated retrospectively and patients 65 years and older were recruited. Two groups were made according to age: group1 composed of patients age range between 65 and 85 years and group 2 composed of patients 85 years and older. Gender, presence of diabetes mellitus (DM), hypertension (HT), drug use were noted. The results of best corrected visual acuity (BCVA) converted to LogMar, intraocular pressure (IOP) before and 3 months after operation, biomicroscopic and fundus examinations were investigated. Additional ocular diseases such as glaucoma, age related macular degeneration (AMD), pseudoexfoliation syndrome, retinopathies and maculopathies related to systemic diseases were noted. Pupil dilation properties were also noted as poor, mid or full pupil dilation. Cataract surgery techniques such as phacoemulsification, extra- and intracapsular lens extractions, peroperative complications, intracameral drug use were investigated. these aforementioned outcomes evaluated and compared between groups.

Official Title
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Outcomes of Cataract Surgeries in Patients With Advanced Age

Conditions
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Cataract Senile

Intervention / Treatment
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* Procedure: Cataract Surgery


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients aged 65 years and older patients who underwent cataract surgery Exclusion Criteria: patients aged below 65 years who underwent cataract surgery

Ages Eligible for Study
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Minimum Age: 65 Years
Maximum Age: 95 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Group 1, patients aged 85 years and older<br>75 eyes of 75 patients (39 female, 36 male) Mean age: 86,8 ± 1,8 years | Procedure: Cataract Surgery<br>* Cataract surgery was performed by using phacoemulsification technique, routinely. But other techniques for instance extra or intracapsular cataract extraction (ECCE, ICCE) techniques were performed when needed. Phacoemulsification technique was performed by 2 experienced surgeon (G.A. and E.C.) under topical anesthesia, thorough limbal incision. Foldable single piece hydrophobic acrylic intraocular lens (IOL) was inserted in the bag. In the presence of complications related to anterior or posterior capsules, 3 pieces IOL was preferred. When ECCE technique was chosen, single piece polymethyl methacrylate IOL was inserted.<br>|
| Group 2, patients aged 65 and 85 years<br>77 eyes of 77 patients (34 female, 43 male) Mean age:73,3 ± 5,2 years | Procedure: Cataract Surgery<br>* Cataract surgery was performed by using phacoemulsification technique, routinely. But other techniques for instance extra or intracapsular cataract extraction (ECCE, ICCE) techniques were performed when needed. Phacoemulsification technique was performed by 2 experienced surgeon (G.A. and E.C.) under topical anesthesia, thorough limbal incision. Foldable single piece hydrophobic acrylic intraocular lens (IOL) was inserted in the bag. In the presence of complications related to anterior or posterior capsules, 3 pieces IOL was preferred. When ECCE technique was chosen, single piece polymethyl methacrylate IOL was inserted.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Best corrected visual acuity | Best corrected visual acuity converted to LogMar | Before cataract surgery | 
| Best corrected visual acuity | Best corrected visual acuity converted to LogMar | three months after cataract surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| presence of Diabetes Mellitus | number of participants who have diabetes mellitus | Baseline (Before cataract surgery) | 
| presence of essential hypertension | number of participants who have essential hypertension | before cataract surgery | 
| oral acetylsalicylic acid use | number of participants who have a history of acetylsalicylic acid use | before cataract surgery | 
| oral flomax use | number of participants who have a history of oral flomax use | before cataract surgery | 
| presence of age related macular degeneration | number of participants who have age related macular degeneration | Baseline (Before cataract surgery) | 
| presence of glaucoma | number of participants who have glaucoma | before cataract surgery | 
| presence of pseudoexfoliation | number of participants who have pseudoexfoliation | before cataract surgery | 
| presence of poor pupil dilation | number of participants who have poor pupil dilation | During cataract surgery | 
| presence of zonule deficiency | number of participants who have zonule deficiency | During cataract surgery | 
| Cataract types in patients who underwent cataract surgery | number of participants who have nuclear, posterior subcapsular, corticonuclear, mature, nigra, traumatic cataract | Baseline (Before cataract surgery) | 
| measurement of effective phacoemulsification time | measurement of effective phacoemulsification time in participants who underwent cataract surgery | During cataract surgery | 
| presence of posterior capsule rupture | participants who had posterior capsule rupture during surgery | During cataract surgery | 
| anterior vitrectomy | number of participants who needed anterior vitrectomy during cataract surgery | during surgery | 
| presence of aphakia | number of participants who left aphakic after cataract surgery | 3 months after cataract surgery | 
| intracameral adrenalin use | number of participants who needed intracameral adrenalin use | during surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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geriatry, cataract surgery, advanced age