Virtually Supervised Exercise for Kidney Transplant Candidates

Study Overview
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Brief Summary
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This study is examining whether a virtually supervised exercise program can improve physical function in persons who are awaiting kidney transplant. the investigators will compare the results to a similar group of persons who receive a health education program.

Official Title
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Virtually Supervised Exercise for Kidney Transplant Candidates

Conditions
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Physical Disability

Intervention / Treatment
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* Behavioral: Virtually supervised exercise
* Behavioral: Health education


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Listed for kidney transplant Exclusion Criteria: Nursing home resident Severe low vision (≥20/200 with corrective lens) Severe hearing loss even with use of amplification preventing communication Unstable angina or uncontrolled arrhythmia Supplemental oxygen therapy Inability to stand upright Lack of fluency in English Myocardial infarction, major heart surgery, stroke, venous thromboembolism, hip fracture, hip or knee replacement in past six months (temporary exclusion) Current receipt of physical therapy (temporary exclusion)

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 100 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: This study uses a parallel group delayed intervention design. In the first half of the study (Weeks 0 to 12), the intervention arm will receive the virtually supervised exercise intervention, while the active comparator arm will receive the health education program. In the second half of the study (Weeks 13 to 24), the intervention arm will continue the virtually supervised exercise intervention, while the active comparator group will start the virtually supervised exercise intervention. The primary timepoint of interest will be at 12 weeks.
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Virtually supervised exercise<br>In the first half of the study (weeks 0 to 12), participants will receive a virtually supervised exercise program. In the second half of the study (weeks 13 to 24), participant will continue to receive the virtually supervised exercise program. | Behavioral: Virtually supervised exercise<br>* Participants will participate twice weekly in an live exercise program that they will access through a computer connected to the Internet.<br>|
| Active Comparator: Health education<br>In the first half of the study (weeks 0 to 12), participants will receive a health education program. In the second half of the study (weeks 13 to 24), participant will receive a the virtually supervised exercise program. | Behavioral: Virtually supervised exercise<br>* Participants will participate twice weekly in an live exercise program that they will access through a computer connected to the Internet.<br>Behavioral: Health education<br>* Participants will first participate in a once weekly live health education class that they will access through a computer connected to the Internet. During the second half of the study, participants will participate twice weekly in an live exercise program that they will access through a computer connected to the Internet.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in performance on 30 second sit to stand test | Number of times that a person can stand up from a sitting position in 30 seconds | Baseline through week 12 |