Continuous MONItoring of Blood LActate and Glucose Levels Using a New Central Veinous Microdialysis Catheter Device

Study Overview
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Brief Summary
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Continuous lactate and glucose blood levels

Detailed Description
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MAQUET Group offers a new device that gives real time blood lactate and glucose levels. It is a new central veinous catheter with a microdialysis system. It is planted in the superior vena cava. It has not yet been used and validated with a clinical purpose, and particularly in cardiac surgery. For now, reference method for determining blood lactate and glucose levels is co oxymetry. This new simple device could provide great fluency for determining blood lactate and glucose levels. It could allow medical teams gain time for diagnosis and treatment of both hyperlactatemia and hyperglycemia. The primary outcome of this study was to compare blood lactate and glucose absolute measures provided with the MAQUET new device (Maquet Critical Care AB, Solna, Sweden) and with co oxymetry. The secondary outcome of this study was to compare variations of these absolutes measures.

Official Title
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Monitorage Continu du Lactate et de la glycémie Par Microdialyse : Une étude de Validation en Chirurgie Cardiaque.

Conditions
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Other Functional Disturbances Following Cardiac Surgery

Intervention / Treatment
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* Device: comparison of blood lactate and glucose levels


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Men or women more than 18 years old. Cardiac surgery. Central veinous catheter in superior vena cava. Exclusion Criteria: Men or women less than 18 years old. Pregnant women. Central veinous catheter not in superior vena cava.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Device: comparison of blood lactate and glucose levels|comparison of blood lactate and glucose levels with the reference method (co oxymetry) and a new central veinous catheter microdialysis system provided by MAQUET. (Critical Care AB, Solna, Sweden.)|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| comparison of absolute blood lactate and glucose levels with the reference method (co oxymetry) and a new method using a device providing real time measures of lactate and glycemia with a central veinous catheter microdialysis system. | Central veinous catheter, EIRUS (Maquet Critical Care AB, Solna, Sweden) | 1 day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| comparison of variations of blood lactate and glycemia levels with the reference method (co oxymetry) and a new method using a device providing real time measures of lactate and glycemia. (EIRUS) with a central veinous catheter microdialysis system. | Central veinous catheter, EIRUS (Maquet Critical Care AB, Solna, Sweden) | 1 day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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EIRUS, lactate, continuous lactate monitoring, continuous blood glucose monitoring, blood glucose, cardiac surgery, central veinous catheter, microdialysis