A Retrospective Non-interventional Study to Evaluate the Use of Seroquel Extended Release (XR) and Immediate Release (IR) in the Clinical Practice of Inpatients With Schizophrenia

Study Overview
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Brief Summary
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The primary objective of this non-interventional study is to investigate how Seroquel XR and Seroquel IR are used in the clinical practice of inpatients with schizophrenia. This will be done by a retrospective review of medical records to evaluate patients treated with Seroquel XR or Seroquel IR as primary antipsychotic treatment.

Official Title
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A Retrospective, Non-interventional Study to Evaluate the Use of Seroquel XR and Seroquel IR in the Clinical Practice of Inpatients With Schizophrenia

Conditions
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Schizophrenia

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Diagnosis of schizophrenia. At least one dose of Seroquel XR or Seroquel IR during the study period (1st of July 2009 - 30th of September 2010). Hospitalization due to psychotic symptoms at any time during the study period (1st of July 2009 - 30th of September 2010) and with admission and discharge dates available. Exclusion Criteria: Participation in a clinical trial during the study period. Treatment in forensic care according to LRV (Lagen om Rättspsykiatrisk Vård).

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| 1<br>Patients with a diagnosis of schizophrenia who have been hospitalized and received at least one dose of Seroquel XR or Seroquel IR during the study period (1st of July 2009 - 30th of September 2010). | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To investigate how Seroquel XR and Seroquel IR are used in the clinical practice of inpatients with schizophrenia |  | every day for the time period of 15 Oct to 31 Dec 2010 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To investigate comorbidities of patients with schizophrenia receiving Seroquel XR and IR |  | every day for the time period of 15 Oct to 31 Dec 2010 | 
| To investigate whether Seroquel XR and Seroquel IR are used to treat different types of inpatients with schizophrenia by evaluation of patient characteristics |  | every day for the time period of 15 Oct to 31 Dec 2010 | 
| To investigate the treatment sequence of Seroquel XR and Seroquel IR in the clinical practice of patients with schizophrenia by evaluation of duration, dosage, reason for treatment, and, if applicable, reason for change, with Seroquel XR and Seroquel IR |  | every day for the time period of 15 Oct to 31 Dec 2010 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Mental disorder, antipsychotic treatment