University Of Pennsylvania Weight Loss Study

Study Overview
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Brief Summary
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This is a 4-arm, randomized controlled trial to evaluate the effectiveness of financial incentives to motivate and sustain long-term weight loss. The study will recruit eligible employees at a large health management company to participate in a 6-month weight loss program and have weight measurements for an additional 3-month follow-up period. The primary outcome measure in this randomized controlled trial will be pounds of weight lost. The experimental groups will include variations of deposit contracts (participants put their own money at risk, and lose that money if they fail to achieve their weight loss goal) and fixed payments. The use of deposit contracts is a powerful mechanism for inducing behavior change that is based on loss aversion, a psychological concept first described by Nobel Prize winner Daniel Kahneman and Amos Tversky in 1979. A deposit contract takes advantage of the fact that people typically feel the pain of a loss more than the pleasure of a gain, increasing ones motivation to reach a goal. The study hypotheses are 1) mean weight loss will be greater in all intervention groups compared to the control group by the end of 24 weeks; and 2) individuals in the intervention groups will have a lower mean weight at the end of the 3-month follow-up period than individuals in the control group.

Official Title
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University Of Pennsylvania Weight Loss Study

Conditions
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Weight Loss

Intervention / Treatment
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* Behavioral: Deposit contract with a 1:1 match
* Behavioral: Deposit contract with a 2:1 match
* Behavioral: Deposit Contract with no match


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Aged 18 to 70 (inclusive) BMI between 30 and 50 (inclusive) Exclusion Criteria: Inability to consent No known Illiteracy and/or inability to speak, read, and write English Participation in another weight loss program Participation in another research study Current treatment for drug or alcohol use Consumption of 5 alcoholic drinks per day Myocardial infarction or stroke within the past 6 months Uncontrolled hypertension (defined as BP170 mm Hg systolic or BP110 mm Hg diastolic) Current addiction to prescription medicines or street drugs Serious psychiatric diagnoses (severe depression, schizophrenia) Pregnancy Diabetic and using any medicine besides metformin to control blood sugars Metastatic cancer Unstable medical conditions that would likely prevent the subject from completing the study Previous diagnosis of an eating disorder History of unsafe weight loss behaviors such as binging or the use of laxatives

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: 1<br> | |
| Experimental: 2<br>Deposit contract with a 1:1 match | Behavioral: Deposit contract with a 1:1 match<br>* Daily weigh-in for 24 weeks and if each daily goal met daily deposit amount is paid back with an additional matched amount equal to deposited amount. Final weigh-in at 36 weeks with no financial incentive or deposit made.<br>|
| Experimental: 3<br>Deposit contract with a 2:1 match | Behavioral: Deposit contract with a 2:1 match<br>* Daily weigh-in for 24 weeks and if each daily goal met daily deposit amount is paid back with an additional matched amount twice the amount equal to deposited amount. Final weigh-in at 36 weeks with no financial incentive or deposit made.<br>|
| Experimental: Experimental 4<br>Deposit contract with no match | Behavioral: Deposit Contract with no match<br>* Daily weigh-in for 24 weeks and if each daily goal met the daily deposit amount is paid back. Final weigh-in at 36 weeks with no financial incentive or deposit made.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Weight | Change in weight between baseline and 24 weeks | 24 Weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Weight Loss, Motivation, Contracts