The Effect of Early Physiotherapy on Biochemical Parameters in Major Burn Patients: A Burn Center's Experience

Study Overview
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Brief Summary
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Background: This study planned to investigate the effect of early physiotherapy on biochemical parameters in major burn patients. Methods: Ten women (50%) and 10 men (50%) aged 21-47 years old were included in our study. Participants were divided into two groups: one group was the treatment group and the other was the control group. In the treatment group, patients were admitted to the physiotherapy programme from the first day they have been hospitalised, in addition to their routine treatment (medical, surgery, etc.), for 4 days per week. It consisted of parameters such as early mobilisation and ambulatory training, chest physiotherapy, and both active and passive normal joint movement exercises. The days of treatment were determined as Tuesday, Wednesday, Thursday and Friday. Patients could not be treated on a Monday because that was surgery day. The control group consisted of patients who could not receive physiotherapy due to various reasons. All patients included in the study were evaluated weekly for 6 weeks after admission to the hospital. Parameters such as demographic information, characteristics of burn injury, C-reactive protein, fibronectin, transferrin and prealbumin were evaluated.

Official Title
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The Effect of Early Physiotherapy on Biochemical Parameters in Major Burn Patients: A Burn Center's Experience

Conditions
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Burns, Physiotherapy, Exercises

Intervention / Treatment
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* Other: Burn Physiotherapy Protocol


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age ≥ 18 years Major burn injury (according to ABA) Conscious patients Exclusion Criteria: Inhalation injury Various chronic disorders Organ dysfunctions

Ages Eligible for Study
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Minimum Age: 21 Years
Maximum Age: 47 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Burn Physiotherapy Protocol Group<br>Patients in the treatment group have been received to the physiotherapy programme from the first day of their stay in the hospital. | Other: Burn Physiotherapy Protocol<br>* It consisted of parameters such as early mobilisation and ambulatory training, chest physiotherapy, and both active and passive normal joint movement exercises.<br>|
| No Intervention: Control Group<br>The control group consisted of patients who could not receive physiotherapy due to various reasons. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Fibronectin | Blood test | Changes in fibronectin at 6 weeks later | 
| Prealbumin | Blood test | Changes in prealbumin at 6 weeks later | 
| C-reactive protein | Blood test | Changes in C-reactive protein at 6 weeks later | 
| Transferrin | Blood test | Changes in transferrin at 6 weeks later | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Fibronectin, Prealbumin, Physiotherapy, Major Burns, biochemical parameters