New Psychoactive Substances in Intoxicated Patients During the Winter Activities

Study Overview
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Brief Summary
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The purpose of this research is to identify the New Psychoactive Substances (NPS) that are responsible for intoxicating patients in ski resort during winter activities.

Detailed Description
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The New Psychoactive Substances expose to an additional risk of overdose or death due to their potency. These New Psychoactive Substances are used voluntarily by users wishing to test new substances, but also involuntarily because of association (unknowingly users) with more conventional drugs such as cocaine or heroin in the self-administered powder. These intoxications are still poorly known and the investigators believe that the identification of New Psychoactive Substances among the drugs consumed, and the association of their consumption with the appearance of a particular symptomatology allow the physician to guide the diagnosis and facilitate the care of future patients.

Official Title
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Consumption of New Psychoactive Substances in Intoxicated Patients During the Winter Activities

Conditions
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Acute Intoxication, Psychoactive Substance Use

Intervention / Treatment
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* Other: urine analysis


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Admission to emergency, resuscitation or intensive care departments involved in the study Anamnestic and / or clinical suspicion of acute drug poisoning according to International Classification of Diseases-10 criteria Patient coming from a ski resort from the pre-established list urine sample available as part of the treatment person understanding French or English Non-opposition to the study Exclusion Criteria: Suspicion of alcohol intoxication alone Suspicion of voluntary drug poisoning Suspicion of intentional intoxication by others Pregnant or breastfeeding women Major mentioned in Articles L1121-6 and 1121-8 of french public health code Patients in the exclusion period of another research involving the human person type 1 or 2

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| suspicion of intoxication<br>New Psychoactive Substances research in urine | Other: urine analysis<br>* New Psychoactive Substances research in urine at admission in unit care<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| positive urinary sample | proportion of urine samples positive for New Psychoactive Substances and related, among patients suspected of intoxication and from a ski resort, in winter. | Day 0 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| incidence of toxidromes | Clinical symptoms observed in intoxicated patients | baseline | 
| polyintoxication frequency | Percentage of co-intoxications | baseline | 
| morbidity of intoxication | length of stay in hospital | baseline and month 1 | 
| morbidity of intoxication | Percentage of Intensive Care Unit admissions | baseline and month 1 | 
| incidence of intoxication medical care | names of therapies implemented within 24 hours of admission | day 1 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Intoxication; Psychoactive Substance ; Ski