HYSTERIA Evaluation of Clinical HYpnosis After Surgical Resection for Crohn Disease on Post-operative Analgesia

Study Overview
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Brief Summary
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The aim of this study will be to show a decrease in postoperative morphine consumption by the practice of perioperative self-hypnosis in patients undergoing laparoscopic ileo-caecal resection for Crohn's disease

Official Title
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Prospective Randomized Study Evaluating the Effect of Pre-operative Hypnosis on Anesthesia, Analgesia and Perioperative Stress Laparoscopic Ileo-caecal Resections of Crohn's Disease.

Conditions
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Inflammatory Bowel Diseases, Anesthesia

Intervention / Treatment
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* Procedure: Hypnosis
* Procedure: usual care


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Being affected by a crohn's disease, reaching the small intestine (ileal or ileo-colic) and requiring ileo-caecal resection by laparoscopy Never been operated for abdominal crohn's disease Exclusion Criteria: Pregnant women A history of intestinal resection for crohn's disease Emergency surgery Corticotherapy in progress Deaf patients non-Francophone Patients Patients with knowledge of self-hypnosis

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: With preoperative hypnosis<br>standard care plus hypnosis followed by administration of propofol for anesthesia induction | Procedure: Hypnosis<br>* A short preanesthetic hypnosis before induction of anesthesia<br>|
| Active Comparator: Without preoperative hypnosis<br>standard care without preoperative hypnosis followed by administration of propofol for anesthesia induction | Procedure: usual care<br>* Standard care before induction of anesthesia<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Total morphine consumption | Compare the cumulative morphine consumption during 24 hours postoperative Data from PCA pump and patient medical record | During the first 24 postoperative hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Total morphine consumption | Compare the cumulative morphine consumption between the 24 and the 48 postoperative hours Data from PCA pump and patient medical record | between the 24 and the 48 postoperative hours | 
| Total number of patients with complications |  | during first 7 postoperative days | 
| Intraoperative consumption of hypnotics and opioids | The hypnotics and opioids drug dose will be recorded | during first 7 postoperative days | 
| Antiemetics consumption | The antiemetic drug dose will be recorded | during first 7 postoperative days | 
| Postoperative nausea and vomiting (PONV) Score | PONV risk assessment tool Based on apfel's simplified risk score | first 24 postoperative hours | 
| Duration of hospital stay |  | during first 7 postoperative days | 
| Time physiological function recovery | Ability to drink, to eat, to urinate, to walk | during first 7 postoperative days |