Cortical Bone Plate Versus Cortico-cancellous Block Graft

Study Overview
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Brief Summary
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Horizontal ridge augmentation using either cortical bone plate technique or cortico-cancellous block graft was the aim of the study. Bone quality was analyzed histomorphomterically, and horizontal dimensional changes were assessed using CBCT.

Official Title
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Cortical Bone Plate Versus Cortico-cancellous Block Graft for Horizontal Ridge Augmentation: Histomorphometric and Cone Beam Computed Tomography Study

Conditions
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Horizontal Atrophy of Edentulous Alveolar Ridge

Intervention / Treatment
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* Procedure: Split-block technique
* Procedure: Cortico-cancellous block graft


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Eligible patients aged 18 years or older with partial edentulism of the mandible The residual ridge width must be 4 mm or less Intra-oral donor sites should be available in the external oblique ridge and symphyseal area Exclusion Criteria: Patients with general contraindications for implant surgery such as uncontrolled diabetes Irradiation of the head and neck region Intravenous bisphosphonate Pregnancy Smokers, alcoholics and drug abusers

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Cortical bone plate<br>A cortical plate was harvested from the external oblique ridge and split in half. Then one plate was fixed at a distance from the atrophied ridge and autogenous bone chips were used to fill the gap between the plate and the ridge. | Procedure: Split-block technique<br>* Horizontal ridge augmentation using the split-block technique where a cortical bone plate harvested from the external oblique ridge was split in half and fixed at a distance from the atrophied ridge. Then autogenous bone chips were packed in the gap between the plate and the ridge.<br>|
| Active Comparator: Cortico-cancellous block graft<br>A cortico-cancellous block graft was harvested from the symphysis of the mandible and fixed to the atrophied ridge. | Procedure: Cortico-cancellous block graft<br>* Horizontal ridge augmentation using a cortico-cancellous block harvested from the chin of the mandible.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluation of bone quality | Histomorphometric analysis (Masson's Trichrome stain) | 4 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Horizontal ridge dimensional changes | Measuring the linear horizontal changes using CBCT | 4 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Split-bone block technique, Cortical bone plate, Cortico-cancellous block graft