Prevalence of Peripheral Arterial Disease in Subject With a Moderate Risk of Cardiovascular (CV) Disease (CVD) in Primary Prevention

Study Overview
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Brief Summary
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Non interventional study aimed to establish the prevalence of lower extremity peripheral arterial disease (PAD), defined as an ankle-brachial index (ABI) not above 0.90 in subjects with a moderate risk of cardiovascular disease, with no overt cardiovascular diseases nor diabetes mellitus.

Official Title
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Prevalence of Peripheral Arterial Disease in Subjects With a Moderate CVD Risk, With No Overt Vascular Diseases nOR diAbetes Mellitus

Conditions
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Peripheral Arterial Disease (PAD), Moderate Risk for Cardiovascular Disease (CVD)

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Male subject aged 45 years or above, or female subject aged 55 years or above (age-related CVD risk factor) At least another of the following risk factor for CVD: cigarette smoking, hypertension, low HDL cholesterol or high LDL cholesterol, family history of premature coronary heart disease, elevated waist circumference Willingness to participate in the survey and complying with the study by signing a written informed consent Exclusion Criteria: No or 1 risk factor for CVD; symptoms of PAD; diabetes mellitus; coronary heart disease or equivalents No lipid data collected in the last 12 months Serious or unstable medical or psychological conditions that, in the opinion of the Investigator, would compromise the subject's safety or successful participation in the study; unwilling or unable to provide informed consent

Ages Eligible for Study
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Minimum Age: 45 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| 1<br>Subjects of either sex, any race, with at least two CVD risk factors, with no overt cardiovascular diseases nor diabetes mellitus | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prevalence of lower extremities peripheral arterial disease (PAD), in subjects with a moderate CVD risk, with no overt cardiovascular diseases nor diabetes mellitus |  | 1 visit | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prevalence of cardiovascular risk factors in subjects with at least two CVD risk factors, with no overt cardiovascular diseases nor diabetes mellitus |  | 1 visit | 
| Cardiovascular risk level and risk factor treatment in the selected population assessed according to the locally adopted risk charts or algorithms |  | 1 visit | 
| Determinants (i.e., subject and physician characteristics) for PAD underdiagnosis in the selected population |  | 1 visit | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Peripheral Arterial Disease (PAD), Cardiovascular Disease (CVD), Atherosclerotic cardiovascular disease, Atherosclerosis, Primary CVD prevention