Water Intake Associated With Aerobic Exercise in Coronary

Study Overview
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Brief Summary
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The need to restore water losses resulting from physical activity has become established and diffused into international consensus for healthy individuals or high-performance athletes. However, the influence of fluid replacement when administered during and after exercise on cardiorespiratory parameters, cardiac autonomic modulation, and subjective perceptions of effort and pain of individuals with autonomic alterations known as the coronary arteries remain poorly understood. In this sense, this study intends to investigate the influence of hydration on cardiac autonomic modulation, cardiorespiratory parameters, subjective perception of exertion and pain of coronary arteries submitted to aerobic exercise in the model of a cardiovascular rehabilitation session. A total of 31 individuals will be recruited in this study and will perform four standardized cardiovascular rehabilitation sessions. Only in the second and the fourth session will the volunteers be instructed to ingest a quantity of water predetermined by the evaluator, based on the loss of body mass measured in the first and the third sessions. The outcomes (autonomic modulation, cardiorespiratory variables and perceptions) will be evaluated before, during and after exercise. The results of this study will enable professionals working with this population to implement awareness strategies on the importance of fluid intake in cardiovascular rehabilitation programs.

Official Title
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Influence of Hydration on Autonomic Behavior and Cardiorespiratory Parameters of Coronaropathy Submitted to Aerobic Exercise

Conditions
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Coronary Artery Disease

Intervention / Treatment
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* Other: Treadmill aerobic exercise in supine position
* Other: Treadmill aerobic exercise and water intake in supine position
* Other: Treadmill aerobic exercise in orthostatic position
* Other: Treadmill aerobic exercise and water intake in orthostatic position


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Men with coronary heart disease ischemia, over 45 years At least three months of cardiovascular rehabilitation Exclusion Criteria: smokers, alcoholics Uncontrolled metabolic disease (eg, uncontrolled diabetes and thyroid diseases) Abnormal hemodynamic responses during exercise such as disproportionate increase / fall of heart rate and / or blood pressure to low / high levels of load myocardial ischemia and / or severe ventricular arrhythmias during the exercise test

Ages Eligible for Study
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Minimum Age: 45 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Non-Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Control group in supine position<br>Intervention: - Only treadmill aerobic exercise with 60 min recovery in supine position | Other: Treadmill aerobic exercise in supine position<br>* The volunteers will be submitted to a cardiovascular rehabilitation session with 40 minutes of treadmill aerobic exercise followed by 60 minutes of recovery at the supine position.<br>|
| Experimental: Hydration group in supine position<br>Interventions: Treadmill aerobic exercise with 60 min recovery in supine position Water intake | Other: Treadmill aerobic exercise and water intake in supine position<br>* The volunteers will be submitted to a cardiovascular rehabilitation session with 40 minutes of treadmill aerobic exercise and water intake followed by 60 minutes of recovery at the supine position.<br>|
| Active Comparator: Control group in orthostatic position<br>Intervention: - Only treadmill aerobic exercise with 10 min recovery in orthostatic position | Other: Treadmill aerobic exercise in orthostatic position<br>* The volunteers will be submitted to a cardiovascular rehabilitation session with 40 minutes of treadmill aerobic exercise followed by 10 minutes of recovery at the orthostatic position.<br>|
| Experimental: Hydration group in orthostatic position<br>Interventions: Treadmill aerobic exercise with 10 min recovery in orthostatic position Water intake | Other: Treadmill aerobic exercise and water intake in orthostatic position<br>* The volunteers will be submitted to a cardiovascular rehabilitation session with 40 minutes of treadmill aerobic exercise and water intake followed by 10 minutes of recovery at the orthostatic position.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Heart rate variability | Indices of heart rate variability | up to six months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Subjective Effort Perception | Borg Scale | up to six months | 
| Subjective Pain Perception | Borg CR-10 Scale | up to six months | 
| Cardiovascular parameter | Heart Rate | up to six months | 
| Cardiovascular parameter | Blood Pressure | up to six months | 
| Cardiorespiratory parameter | Respiratory frequency | up to six months | 
| Cardiorespiratory parameter | Partial Oxygen Saturation | up to six months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Autonomic Nervous System, Fluid Therapy, Heart Rate, Exercise