Smoking Cessation Program in the Preadmission Clinic: The Use of a Teachable Moment

Study Overview
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Brief Summary
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The Objective of this study is to introduce a practically feasible multifaceted intervention in the preadmission clinic to help reduce smoking in preoperative surgical patients. The investigators aim to study the effectiveness of such a program in promoting positive change in smoking behavior among patients before surgery. The forced abstinence enforced on patients during hospital stay for their surgery can also be used to help smokers remain tobacco free long term. A significant percentage of surgical patients will be receptive to smoking cessation interventions in the preadmission clinic and will refrain from smoking at 24 and 52 weeks after starting the treatment.

Conditions
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Smoking

Intervention / Treatment
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* Drug: Champix


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: The investigators will recruit patients who are assessed in preadmission clinic and scheduled for elective surgical procedures within the next 8 to 30 days. Patients should be 18 yrs of age, have smoked an average 10 cigarettes/day or more during the previous year and had no period of smoking abstinence longer than 3 months in the past year. Exclusion Criteria: current pregnancy, breastfeeding; major depression, panic disorder, psychosis, or bipolar disorder within the prior year; use of nicotine replacement or bupropion within the previous 3 months; cardiovascular disease within the past 6 months; a serious or unstable disease within the past 6 months; drug or alcohol abuse or dependence within the past year; and use of tobacco products other than cigarettes or marijuana use within the previous month; participating in any other studies Patients who cannot understand English or have any form of cognitive impairment will be excluded.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Placebo Comparator: Placebo<br>patient will receive placebo pills | Drug: Champix<br>* Days 1 - 3: 0.5 mg once daily (1 table each day) Days 4 - 7: 0.5 mg twice daily (1 in the morning and 1 in the evening) Days 8 - 12 weeks 1.0 mg twice daily (1 in the morning and 1 in the evening)<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| A significant percentage of surgical patients will be receptive to smoking cessation interventions in the preadmission clinic and will refrain from smoking at 24 and 52 weeks after starting the treatment. |  | 2 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Patients who receive interventions but do not quit smoking will have reduced number of cigarettes consumed /day or improved stage of change (determined by Prochaska and DiClemente's Model) at 24 and 52 weeks after starting the treatment. |  | 2 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Smoking, surgery, Anesthesia, quit