Magnetic Resonance Imaging to Detect Signs of Viral Pneumonia in Patients With Coronavirus Infection.

Study Overview
=================
Brief Summary
-----------------
Since the onset of the COVID-19 pandemic, the importance of chest computed tomography (CT) in detecting signs of viral pneumonia has become clear from the literature. However, the increased patient flow creates an additional pressure on CT centers. We believe, the use of chest magnetic resonance imaging (MRI) can help to test patients for CОVID-19 when CT scan is not available. Lung MRI may be useful in routing a patient in a difficult epidemiological situation.

Detailed Description
-----------------
Currently, with increased load of CT studies, alternative methods of viral pneumonia signs' visualization are required. Investigators hypothesize that chest MRI could be a test for detecting pulmonary features of COVID-19. They consider using MRI to assess COVID-19 viral pneumonia. Absence of radiation exposure to patients is a clear advantage of MRI. This is a prospective, observational cohort study assessing patients with suspected COVID-19. It's primary goal is to determine the ability of multiparametric MRI to detect lung abnormalities - ground-glass opacity (GGO), consolidation, crazy paving pattern, pleuritis - in comparison to CT scan. In this study each patient with suspected pneumonia will sequentially undergo both chest CT and MRI during his/her visit. Scan protocols will be identical for each patient. Each participants completed an online questionnaire.

Official Title
-----------------
Possibilities of Chest Magnetic Resonance Imaging (MRI) in Diagnostics of COVID-19. The Use of MRI to Assess Lung Damage in Patients With Coronavirus Infection

Conditions
-----------------
Coronavirus Infections, Pneumonia

Intervention / Treatment
-----------------
* Diagnostic Test: Chest MRI


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: A referral from the attending physician for a chest CT scan Suspected pneumonia Signed informed consent Over 18 years old Exclusion Criteria: Pregnant or nursing women Presence of foreign implanted objects in the body at the scan level (including cardiac pacemakers, spine metalware)

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients with suspected pneumonia COVID-19<br>Chest MRI findings: bilateral, diffuse ground-glass opacity (GGO), consolidation, crazy paving pattern, pleuritis. | |
| Patients with suspected pneumonia with COVID -19<br>Chest CT findings: bilateral, diffuse ground-glass opacity (GGO), consolidation, crazy paving pattern, pleuritis. | Diagnostic Test: Chest MRI<br>* Patients referred by the primary care physician with suspected pneumonia<br>* Other names: Chest CT scan;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of zones of pulmonary parenchyma corresponding to viral pneumonia detected by chest MRI in comparison with CT scan | Expected number - more than two zones | Upon completion, up to 1 year | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Computed tomography, Magnetic resonance imaging, Lung MRI