The Effect of Centella Asiatica Cream on Scar Tenderness Who Underwent Open Carpal Tunnel Release Surgery

Study Overview
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Brief Summary
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The centella asiatica cream applied to the wrist after the CTR surgery was found to be beneficial in preventing the scar tenderness in the thenar and hypothenar regions of the hand.

Detailed Description
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Aim: This study was performed to evaluate the efficacy of centella asiatica extract in a cream preparation for the prevention of scar tenderness formation in patients who underwent conventional open carpal tunnel release surgery.

Official Title
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The Effect of Centella Asiatica Cream on Scar Tenderness in Patients Who Underwent Open Carpal Tunnel Release Surgery

Conditions
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To Prevent Scar Formation for Patients Underwent Surgery

Intervention / Treatment
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* Drug: undefinedCentella Asiatica Extract


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patient underwent open carpal tunnel release surgery - Exclusion Criteria:before hand surgery and recurrent carpal tunnel release surgery. -

Ages Eligible for Study
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Minimum Age: 19 Years
Maximum Age: 90 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: 280 operated patient with carpal tunnel release surgery.
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: vss<br>Vancouver Scar Scale (VSS) at the one, three and 6 months after surgery | Drug: undefinedCentella Asiatica Extract<br>* All patients were asked about scar hypertrophy, scar tenderness, and pillar pain. The scar assessment was performed using the Vancouver Scar Scale (VSS) at the one, three and 6 months after surgery. Patients were asked to complete pre- and postoperative functional evaluations. The VAS score and QuickDASH test was used<br>* Other names: centella asiatica extract;|
| Experimental: QuickDASH , VAS<br>, Quick Disabilities of Arm Shoulder and Hand functional score (QuickDASH) and Visual Analogue Scale (VAS) test was used to determine overall hand function, activities of daily living, work performance, pain, aesthetics, and satisfaction with hand function | Drug: undefinedCentella Asiatica Extract<br>* All patients were asked about scar hypertrophy, scar tenderness, and pillar pain. The scar assessment was performed using the Vancouver Scar Scale (VSS) at the one, three and 6 months after surgery. Patients were asked to complete pre- and postoperative functional evaluations. The VAS score and QuickDASH test was used<br>* Other names: centella asiatica extract;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| centella asiatica extrate | treatment | 10 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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carpal tunnel syndrome, centella asiatica, surgery, cosmetic outcome, wound healing