The Prevalence and Risk Factors of Irritable Bowel Syndrome Among Adults

Study Overview
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Brief Summary
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This is a multicenter cross-sectional study on the prevalence of Irritable Bowel Syndrome and the risk factors associated with it. The Rome IV criteria is used for diagnosing IBS. A questionnaire-guided interview will be applied to all subjects.

Detailed Description
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: Irritable Bowel Syndrome (IBS) is a common functional bowel disorder characterized by abdominal pain or discomfort associated with defecation or an altered bowel habit. IBS can be divided into four subtypes according to the predominant bowel pattern: diarrhea-predominant (IBS-D), constipation-predominant (IBS-C), and both diarrhea and constipation (IBS-M), and when a stool pattern cannot be categorized under any of the above three patterns (IBS-U). For clinicians, diagnosis of IBS can be challenging because symptoms can be variable over time, and what makes it a real challenge is the absence of a gold diagnostic standard for this syndrome. That is why experts developed the Rome criteria in 2006, which is constantly revised. The latest update of these criteria was published in 2016 as Rome IV. Unfortunately, studies have indicated higher rates of psychological comorbidity including suicidal ideation and depression among IBS patients, and a significant reduction in health-related quality of life, this negatively affects the productivity of the individual in society. Epidemiological studies of this syndrome have indicated a greater prevalence among women than men, and adolescents among other age groups. However, despite these attempts by researchers to determine the prevalence patterns and risk factors for this syndrome, many of them are still not sufficiently defined. Hence, our study came to determine the prevalence and risk factors of Irritable Bowel Syndrome among adults.

Official Title
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The Prevalence and Risk Factors of Irritable Bowel Syndrome Among Adults: A Multi-Centre Cross-sectional Study.

Conditions
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Irritable Bowel Syndrome, Colonic Diseases, Functional

Intervention / Treatment
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* Other: ROME IV Criteria


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Volunteer to participate in the study Exclusion Criteria: Poorly-controlled hyperthyroidism Poorly-controlled hypothyroidism Poorly-controlled hyperparathyroidism Liver disease Paralysis Parasitic diseases (worms ...) Celiac disease Inflammatory bowel disease (Crohn's disease or Ulcerative colitis) Lactose intolerance Cancer or tumor in the digestive tract

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients diagnosed with IBS<br>Collaborators will use Rome IV criteria for diagnosing IBS, and then divide participants into those with and without the disease. | Other: ROME IV Criteria<br>* Collaborators will use Rome IV criteria for diagnosing IBS by the presence of the abdominal pain at least once a week in the last 3 months, in addition to at least two of the following: abdominal pain related to defecation, change in stool frequency, or shape.<br>|
| Patients not diagnosed with IBS<br>Collaborators will use Rome IV criteria for diagnosing IBS, and then divide participants into those with and without the disease. | Other: ROME IV Criteria<br>* Collaborators will use Rome IV criteria for diagnosing IBS by the presence of the abdominal pain at least once a week in the last 3 months, in addition to at least two of the following: abdominal pain related to defecation, change in stool frequency, or shape.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The Prevalence of Irritable Bowel Syndrome | Collaborators will make an interview questions using ROME IV to diagnose IBS among adults. | 30 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Physical activity as risk factor for IBS | Collaborators will use the World Health Organization questionnaire to classify the physical activity of the participants into good and poor physical activity. | 30 days | 
| Perceived Stress Scale as risk factor for IBS | It is the most widely used measure of global perceived stress, and a robust predictor of health and disease. The total score is calculated on the basis of the answers to a series of questions based on monthly stress, and the participant's health status. PSS is a summary measure of ten items (range 0-4 points for every item). It is classified into low (PSS 0-13), moderate (PSS 14-26), and high perceived stress (PSS 27-40). | 30 days | 
| Fatigue as risk factor for IBS | Fatigue will be measured using the Chalder Fatigue Scale (CFQ), a self-administered questionnaire for measuring the extent and severity of fatigue within both clinical and non-clinical, epidemiological populations. CFQ is a summary measure of eleven items (range 0-33) | 30 days | 
| Diet and weight questions as risk factor for IBS | Collaborators will use a questionnaire to determine the participant's predominant dietary pattern, feeding patterns and allergies | 30 days | 
| Habits as risk factor for IBS | Smoking, drinking alcohol, caffeine intake, and sleep pattern. | 30 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Rome IV criteria, Colonic Diseases, Digestive System Diseases, Irritable Bowel Syndrome