The Clinical Study of Bundle Measures to Improve the Success Rate of Patients With Difficult Ventilator Weaning

Study Overview
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Brief Summary
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Based on nutritional support, Cardiopulmonary rehabilitation and Levosimendan Bundle measures, and making beside checklist of patients with difficult ventilator weaning; Implementation of nutritional risk, respiratory function, and cardiac function assessment prior to weaning; Regulate the procedure to solve the problem of difficult-weaning patients with Non neurogenic disease in ICU. Thereby,improve the success rate of weaning patients, so as to shorten the ICU hospitalization time, reduce medical costs, reduce the complications of mechanical ventilation, improve the patient's quality of life.

Detailed Description
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Older than 16 years of age, ventilator therapy more than 1 weeks, Ventilator parameters meet the standard of ventilator removal, repeated more than 3 times SBT not successful, or within a short period of time within a week of successful weaning, no other new incentives to need ventilator support again, and delayed weaning from ventilator more than 1 months.

Official Title
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The Clinical Study of Bundle Measures to Improve the Success Rate of Patients With Difficult Ventilator Weaning

Conditions
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Weaning Failure

Intervention / Treatment
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* Other: bundle measures


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Older than 16 years of age, ventilator therapy more than 1 weeks,ventilator parameters up to Weaning standard, repeated more than 3 times Spontaneous Breathing Test(SBT) not successful, or within a short period of time within a week of successful weaning, no other new incentives to re machine induced delayed more than 1 months or more offline. - Exclusion Criteria: Mechanical ventilation patients who are clearly defined as neurological disorders or advanced tumor wasting diseases, as well as those without informed consent. -

Ages Eligible for Study
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Minimum Age: 16 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| research group<br>bundle measures to help patient to weaning ventilator | Other: bundle measures<br>* Implementation of bundle measures to improve the successful rate of weaning ventilator<br>|
| historical control group<br>retrospect the patients who were difficult to wean from ventilator and collect some materials to compare. | Other: bundle measures<br>* Implementation of bundle measures to improve the successful rate of weaning ventilator<br>|
| External control group<br>contrast other same level hospitals measures to patients who are difficult to wean ventilator. | Other: bundle measures<br>* Implementation of bundle measures to improve the successful rate of weaning ventilator<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bundle measures can solve the problem of difficult-weaning patients with Non neurogenic disease in ICU. | Based on nutritional support, Cardiopulmonary rehabilitation and Levosimendan Bundle measures, and making beside checklist of patients with difficult ventilator weaning; Implementation of nutritional risk, respiratory function, and cardiac function assessment prior to weaning; Regulate the procedure to solve the problem of difficult-weaning patients with Non neurogenic disease in ICU. Thereby,improve the success rate of weaning patients, so as to shorten the ICU hospitalization time, reduce medical costs, reduce the complications of mechanical ventilation, improve the patient's quality of life. | From June 1st 2017 to June 30 2020 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Bundle, difficult ventilator weaning