Effect of Dual-Task Training on Pediatric Oncology Patients

Study Overview
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Brief Summary
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It is known that the treatment of children with cancer has negative effects on cognition, muscle strength, balance, and gait. Therefore, the aim of this study is to evaluate the effects of dual-task training, which is based on the principle of simultaneous performance of cognitive tasks and motor tasks, on muscle strength, balance, and gait.

Detailed Description
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With the increase in the incidence of cancer, the number of children who survived cancer is also increasing. Most studies on cancer survivors show that the disease and its treatment have side effects and long-term late effects on the musculoskeletal system, physical function, motor, and cognitive skills. Therefore, the aim of this study is to evaluate the effects of dual-task training, which is based on the principle of simultaneous performance of cognitive tasks and motor tasks, on muscle strength, balance, and gait. This study is planned to be the first study in which dual-task training is applied in children with cancer.

Official Title
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Evaluation of the Effect of Dual-Task Training on Muscle Strength, Balance, and Gait in Pediatric Oncology Patients

Conditions
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Cancer

Intervention / Treatment
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* Other: Dual-task training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Diagnosed with pediatric cancer and inpatient and outpatient treatment in Hematology-Oncology Clinics for treatment, Able to walk alone without any walking aid, Children aged 6-18 will be included Exclusion Criteria: Staying in an isolated room or at risk of infection (neutropenic, etc.), Any orthopedic or neurological disorder that may prevent walking; Having any mental disability that will prevent performing a cognitive task, Individuals with malignant hypertension or unstable heart disease (eg, congestive heart failure) will not be included in the study.

Ages Eligible for Study
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Minimum Age: 6 Years
Maximum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Children with cancer<br>The arm of the research will consist of pediatric patients aged 6-18 years who have been diagnosed with cancer in Afyonkarahisar Health Sciences University, Health Application and Research Center, Department of Pediatric Hematology-Oncology Clinics and who come for outpatient treatment. | Other: Dual-task training<br>* Dual-task training includes simultaneous execution of motor and cognitive tasks. The motor tasks in this study will be walking, going up and downstairs, turning, throwing, and holding a ball. Cognitive tasks will be an n-back test, verbal fluency, remembering sequences of numbers, and performing simple summing.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| gait speed | Gait speed is the time one takes to walk a specified distance on level surfaces over a short distance. It will be recorded in m/s. | 600 seconds | 
| balance | Balance is evaluated with Timed-up and Go Test. The time elapsed during the test is recorded in seconds. | 300 seconds | 
| Muscle strength | Isometric muscle strength will be evaluated with a hand-held dynamometer. It will be recorded in kg. | 600 seconds | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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cancer, gait, postural balance, muscle strength