Assessment of Post-traumatic Stress Disorder (PTSD) in Patients Monitored for Cytomegalovirus (CMV) Seroconversion During Pregnancy,

Study Overview
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Brief Summary
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Reports of maternal seroconversion to CMV during pregnancy can be extremely stressful. This virus is little known to the general public and searching for information on the Internet quickly leads to a consultation of a site mentioning the risk of severe psychomotor retardation in the event of prenatal cytomegalovirus infection. The psychological repercussions in the event of prenatal CMV infection with criteria of severity, leading or not to a request for IMG, is undeniable, but no study has investigated the consequences of seroconversion to CMV without transmission of the virus to the patient fetus, or in the case of transmission without criteria of seriousness, on the patient's experience during and after her pregnancy. Such a study would, if necessary, improve the care and support of these future mothers

Official Title
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Assessment of Post-traumatic Stress Disorder (PTSD) in Patients Monitored for Cytomegalovirus (CMV) Seroconversion During Pregnancy, Without Ultrasound Signs or With Non-serious Ultrasound Signs of Maternal-fetal CMV Infection.

Conditions
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Mothers, Cytomegalovirus Infections, Pregnancy Related

Intervention / Treatment
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* Other: Assessment of post-traumatic stress disorder using the Perinatal Post-traumatic Stress Disorder)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adults Referred to the 3 DAN centers with maternal seroconversion to CMV during their pregnancy, confirmed, with or without confirmed prenatal transmission. Presence of ultrasound signs without criteria of seriousness if the materno-fetal infection is proven. Support between January 1, 2008 and December 31, 2020. No opposition from patient Exclusion Criteria: Reversed or anteconceptional CMV seroconversion Concomitant infection with another infectious agent and suspected cross-reaction Multiple pregnancy Ultrasound and / or MRI severity criteria Medical termination of pregnancy Fetal death in utero Birth <32 weeks and / or birth weight <1500 grams (birth criteria in maternity level IIA) Intercurrent event that may be the cause of an abnormality in psychomotor development Patients protected by justice

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Assessment of post-traumatic stress disorder using the Perinatal Post-traumatic Stress Disorder)|Patients identified as women with cytomegalovirus (CMV) seroconversion during pregnancy will be called on the phoned and ask to participate to the study and to answer the Perinatal Post-traumatic Stress Disorder|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| PTSD evaluation | Assessment of post-traumatic stress disorder using the Perinatal Post-traumatic Stress Disorder scale (PPQ questionnaire) | Through study completion, 3 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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CMV, Pregnancy, PTSD