Comparison of the TOFScan and the WiTOF During Recovery of Neuromuscular Function

Study Overview
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Brief Summary
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The purpose of this study is to compare two neuromuscular blockade monitors on recovery from an ATRACURIUM intra veinous injection for surgery. The TOFscan, a wired connected monitors and the WiTOF, a wireless connected monitor.

Detailed Description
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The secondary objective will be to compare the performance of the two monitors on the abductor pollicis muscle with all the curarisation parameters (TOF, PTC, T4/T1R) and to assess interference occuring during the surgery which could limit the usage of a wireless monitor.

Official Title
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Recovery Evaluation of Two Neuromuscular Blockade Monitoring Devices on Abductor Pollicis Muscle, the TOFScan and the Wireless WiTOF

Conditions
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Neuromuscular Residual Curarization

Intervention / Treatment
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* Device: WiTOF
* Device: TOFscan


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All programmed surgery with intraveinous injection of ATRACURIUM American society of anesthesiology patient score of I, II or III Patient being free of tutorship or curatorship Acceptance of the patient after clear and loyal information Exclusion Criteria: Surgery without access simultaneously to the two arms Emergency surgery Rapid sequence induction Usage of an other curare than ATRACURIUM Contraindication on ATRACURIUM usage Patient with pace maker Patient with Arné score > or = to 11 Patient without social security coverage Pregnant of breastfeeding women Patient under social protection

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: WiTOF<br> | Device: WiTOF<br>* Data collection on the WiTOF monitor<br>|
| Active Comparator: TOFscan<br> | Device: TOFscan<br>* Data collection on the TOFscan monitor<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluate the neuromuscular blockade recovery after intraveinous injection of atracurium with 2 differents monitors. | Comparison on the obtention delay for the T4/T1 ratio superior ou equal to 90% beetween the WiTOF and the TOFScan | During the whole period of the surgical operation maximum 8 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluate the performance of the monitors for the follow up of neuromuscular recovery | Comparison of neuromuscular blockade parameters obtained with the WiTOF and the TOFScan (TOF, PTC, T4/1R) | During the whole period of the surgical operation maximum 8 hours | 
| Number and duration of perturbation from the surgical environnement that could limit the usage of a wireless monitor | Assess what could perturbate the data collection on the wireless monitor | During the whole period of the surgical operation maximum 8 hours |