linjc16/ctgov huggingface dataset:
Simulation Training as a Tool for Teamwork Improvement in Multidisciplinary Intensive Care Team

Study Overview
=================
Brief Summary
-----------------
The purpose of the study is to check whether training mixed teams of physicians and nurses from intensive care units on patient simulators improves teamwork within the teams.

Detailed Description
-----------------
Patient safety and the prevention of medical error are primary goals of healthcare organizations. One of the means of reducing such errors is teamwork improvement. Simulation training, using advanced patient simulators, has been shown to improve diagnostic, resuscitation and technical skills amongst physicians and nurses. We intend to compare simulation training of a mixed team of physicians and nurses, using specifically designed scenarios based on real life experience, to frontal teaching sessions designed to enhance teamwork, by assessing teamwork, using accepted behavioral scales, during routine work, before and after both interventions.

Official Title
-----------------
Experimental Like Observational Study of Teamwork Improvement in Multidisciplinary Intensive Care Team Before and After Simulation Training.

Conditions
-----------------
Education, Health

Intervention / Treatment
-----------------
* Behavioral: simulation training


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: intensive care physicians and nurses working in respiratory ICU willing to participate in the study Exclusion Criteria: unwilling to participate
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Educational/Counseling/Training
Allocation: Non-Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: simulation training|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| improvement in teamwork parameters as measured by previously published tools |  |  | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
intensive care, teamwork, medical errors, education, simulation
Somatic Mindfulness Training for a Healthy Workforce: Student Pilot Sample

Study Overview
=================
Brief Summary
-----------------
This pilot study evaluates a somatic mindfulness training. Reductions in mental and physical health correlates of secondary trauma are assessed using a pretest-posttest design.

Official Title
-----------------
Somatic Mindfulness Training for a Healthy Workforce: Student Pilot Sample

Conditions
-----------------
Occupational-based Secondary Trauma

Intervention / Treatment
-----------------
* Behavioral: Somatic Mindfulness Training


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Participant must be either employed or volunteering as a victim service provider, or enrolled at Montana State University as an undergraduate student. Exclusion Criteria: Participant is under age 18.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 100 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Treatment Group<br>Treatment groups receives the intervention training. | Behavioral: Somatic Mindfulness Training<br>* Educational and experiential training to reduce occupational-based secondary trauma.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Secondary Traumatic Stress Scale | Measures occupational-based secondary traumatic stress using a total scale range of 17(min) to 85 (max). Scores above 37 indicate moderate or higher secondary traumatic stress. | This outcome measure will be assessed at week 15. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Post Traumatic Stress Disorder Checklist for DSM-5 (PCL-5) | Measures symptoms of post-traumatic stress disorder using a total scale range of 0 (min) to 80 (max), with a score of 33 or higher indicating that participants maybe suffering from Post Traumatic Stress Disorder. | This outcome measure will be assessed at week 15. |
Pancreatic Stump Closure After Distal Pancreatic Resection

Study Overview
=================
Brief Summary
-----------------
The aim of this study is to investigate whether finnish binding pancreatico-jejunal anastomosis is feasible and prevents the risk for post operative pancreatic fistula after distal pancreeatectomy.

Official Title
-----------------
Prospective Randomized Study to Decrease Pancreatic Fistula Rate

Conditions
-----------------
Distal Pancreatic Resections

Intervention / Treatment
-----------------
* Procedure: pancreatico-jejunal anastomosis
* Procedure: traditional anastomosis


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patiens which the distal pancreatic resektions the type of resections that is techically possible with finnish binding panceatico-jejunal anastomosis Exclusion Criteria: if the pancreas is not suitable for this kind of anastomosis
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: pancreatico-jejunal anastomosis<br>patients in which the finnish binding pancreatico-jejunal anastomosis is techically possible to perfom during distal pancreatic resektion | Procedure: pancreatico-jejunal anastomosis<br> <br> |
| Active Comparator: traditional anastomosis<br>pancreatic resections with traditional stump closure | Procedure: traditional anastomosis<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| postoperative pancreatic fistula rata |  | 30 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of patients with resection margin on the left side of portal vein as a measure of feasibility. |  | 30 days | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
pancreas, pancreatico-jejunal anastomosis, postoperative pancreatic fistulae
A Study to Assess the Efficacy of XEN-D0501 in Reducing the Cough Frequency in Patients With Chronic Idiopathic Cough

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to determine the effectiveness of XEN-D0501 over placebo in reducing the daytime cough frequency in patients with chronic idiopathic cough. The effectiveness of XEN-D0501 over placebo in reducing capsaicin cough responses, objective 24-hour cough frequency, hourly change in cough frequency, cough severity (via visual analogue scale [VAS]), urge to cough (via VAS), global rating of change scale and Leicester Cough Questionnaire (LCQ) will be evaluated.

Official Title
-----------------
A Double-blind, Randomised, Placebo-controlled, Crossover Study to Assess the Efficacy of XEN-D0501, a Transient Receptor Potential Vanilloid Receptor 1 (TRPV1) Antagonist, in Reducing the Frequency of Cough in Patients With Chronic Idiopathic Cough.

Conditions
-----------------
Chronic Idiopathic Cough

Intervention / Treatment
-----------------
* Drug: XEN-D0501
* Drug: Placebo


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Male/female subjects aged 18 or over with chronic idiopathic cough Exclusion Criteria: Clinically significant medical history Abnormal laboratory results, ECGs or vital signs

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: XEN-D0501<br>4mg BID Days 1-13, 4mg once daily (OD) Day 14 | Drug: XEN-D0501<br> <br> |
| Placebo Comparator: Placebo to Match<br>BID Days 1-13, once daily (OD) Day 14 | Drug: Placebo<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change from baseline at the end of each treatment period in objective daytime cough frequency on XEN-D0501 compared to placebo |  | 12 weeks |
Continuous Postoperative Pulse Oximetry in Patients Presenting for Total Hip and Total Knee Replacement

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to evaluate the incidence of low levels of oxygen as determined by standard pulse oximetry monitor in patients who have had total hip or knee replacement/revision.

Official Title
-----------------
Continuous Postoperative Pulse Oximetry in Patients Presenting for Total Hip and Total Knee Replacement

Conditions
-----------------
Total Knee Replacement

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients undergoing knee replacement or hip replacement/revision Exclusion Criteria: Patients requiring mechanical ventilation after surgery Patients with hemoglobinopathy that cause inaccurate pulse oximetry

Ages Eligible for Study
-----------------
Minimum Age: 19 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Joint Replacement Patients<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Total Hip Replacement/Revision
Pregnancy Rates in IVF After Ovulation Triggering With Recombinant or Urinary Human Chorionic Gonadotrophin (HCG)

Study Overview
=================
Brief Summary
-----------------
To access whether the ovulation triggering with rec-HCG instead urinary-HCG has any impact on the blastulation rate and pregnancy rate of patients undergoing IVF treatment

Official Title
-----------------
Phase III Study on the Effects of Recombinant HCG Ovulation Triggering on Stimulation, Embryonic and Pregnancy Parameters in an IVF Program

Conditions
-----------------
Embryonic Development, Pregnancy, VEGF

Intervention / Treatment
-----------------
* Drug: 10000 IU urinary HCG
* Drug: 250 mcg recombinant HCG


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: FSH<12, normal sperm,less than 36y, single blastocyst transfer Exclusion Criteria: endometriosis stage 3&4, pco

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 36 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Urinary-HCG group<br>These patients received u-HCG for ovulation triggering during ovarian stimulation for IVF | Drug: 10000 IU urinary HCG<br>* ovulation triggering<br>|
| Experimental: Recombinant HCG group<br>These patients received rec-HCG for ovulation triggering during ovarian stimulation for IVF | Drug: 250 mcg recombinant HCG<br>* ovulation triggering<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| blastulation rate |  | on day-5 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| pregnancy rates, VEGF levels, OHSS rate |  | 14 days after oocyte pick up | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
pregnancy occurence, OHSS
DiaCon Overnight Closed-Loop Glucose Control Study

Study Overview
=================
Brief Summary
-----------------
The objective of this in-clinic study is to test our closed-loop glucose control system in patients with type 1 diabetes.

Official Title
-----------------
DiaCon Closed-Loop Study

Conditions
-----------------
Type 1 Diabetes

Intervention / Treatment
-----------------
* Device: Closed-loop control
* Other: Open-loop control


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age 18-65 years Type 1 diabetes duration > 2 years HbA1c < 8% Insulin pump user > 1 year Exclusion Criteria: Use of medication affecting glucose metabolism Pregnancy or nursing

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Closed-loop glucose control<br>Blood glucose controlled by control algorithm. | Device: Closed-loop control<br>* Blood glucose controlled by algorithm<br>* Other names: Metronic Veo-pump. DexCom 7+ sensor.;|
| Active Comparator: Open-loop glucose control<br>Blood glucose controlled by patient | Other: Open-loop control<br>* Blood glucose controlled by patient<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of hypoglycemic events |  | 22:00-07:00 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Time spent in euglycemia (3.9-8.0 mmol/l); mean blood glucose level; LBGI |  | 22:00-07:00 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Type 1 diabetes, Glucose control, Closed-loop, Insulin pump, Glucose sensor
The Postero-superior Contact and Rotator Cuff Lesion

Study Overview
=================
Brief Summary
-----------------
The possibility of physiological contact between the deep surface of the tendon of the supraspinatus muscle and the labrum and/or posterior superior glenoidal rim during an armed movement of the arm (abduction and external rotation or ABER position) has been described for many years. The physiological hypotheses put forward to explain this contact are first of all that the intrinsic mobility of the scapulohumeral joint is limited by these 2 structures, that an anterior instability or micro-instability induces an abnormal anterior translation when performing an abduction and lateral rotation movement, or finally that there is a decrease in humeral retroversion. When this contact becomes symptomatic, it is called a posterior superior conflict. This pathology is mainly found in throwing athletes or athletes repeating maximum external rotation in the abducted position of the arm. This conflict is also described among some manual workers, and is then observed in an older age group.

Official Title
-----------------
Does the Contact Between the Deep Surface of the Supraspinatus Muscle Tendon and the Posterior Superior Labrum Physiological ?

Conditions
-----------------
GLENOID CAVITY

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion criteria: Major subject ((≥18 years old) Operated subject (at the HUS between 01/01/2012 and 31/12/2013) under arthroscopy of anterior instability, of an unruptured tendinopathy of the rotator cuff, or of an extra-articular pathology. Subject not expressing opposition to the use of his data for research purposes Exclusion criteria: Subject having expressed his opposition to participating in the study Patient under safeguard of justice Subject under guardianship or curatorship

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Study of posterior-superior contact in a patient with no rotator cuff lesion. |  | The period from January 1st, 2012 to December 31st, 2013 will be examined | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
GLENOID CAVITY, HUMERAL HEAD, SHOULDER JOINT, SUPRASPINATUS MUSCLE, LABRUM, ABER POSITION, SCAPULOHUMERAL, INTERNAL IMPINGEMENT, ABDUCTED POSITION, SCAPULOHUMERAL JOINT
Patient Experience of Consent for Cancer Surgery in Light of Recent Changes to UK Law- a Questionnaire Study

Study Overview
=================
Brief Summary
-----------------
Since the 2015 Montgomery vs Lanarkshire Health Board ruling, the consent process in the UK has had to change. In practice, this means that doctors must ask themselves whether the patient knows about the material risks of the treatment being proposed, alternatives to the treatment, and whether reasonable care has been taken to ensure the patient actually knows this. This study aims to determine patients' perspectives of consent for major cancer surgery in light of the Lanarkshire ruling.

Detailed Description
-----------------
A patient satisfaction survey was administered to patients who had undergone urological, gynaecological, colorectal, and plastic surgical procedures at a specialised cancer centre where changes to consent processes in light of the Lanarkshire ruling had been implemented.

Official Title
-----------------
Audit of Informed Consent of Patients Undergoing Surgery

Conditions
-----------------
Patient Satisfaction

Intervention / Treatment
-----------------
* Other: Survey


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: All patients who have been admitted and undergone surgery within a 6 week period between April - June 2018. Exclusion Criteria: Any patient who could not complete the survey questionnaire i.e. English was not their first language or to unwell to complete.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Survey|Patients were given a questionnaire/survey to complete in respect of their satisfaction of the consent process for their surgical procedure|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Patients understanding of the risks associated with the procedure they will be having and the alternatives available to them was assessed using a study specific questionnaire. | Was the patient made aware by the clinical care team of the risks associated with their procedure and the alternatives available to them. Were they able to make an informed choice. This will be measured using a patient questionnaire | 6 weeks | 
| Patients views and feelings regarding their experiences in relation to support from healthcare professionals was assessed using a study specific patient questionnaire. | Did patients feel that healthcare professionals provided them with sufficient information and support to make an informed decision in respect of their procedure. This will be measured using a questionnaire completed by patients. | 6 week |
Impact of Intranasal Insulin on Sympathetic Activity and Cerebral Vasodilation

Study Overview
=================
Brief Summary
-----------------
The purpose of this project is to examine the impact of increases in brain insulin on sympathetic nervous system activity, as well as peripheral and cerebral blood flow in humans.

Official Title
-----------------
Impact of Intranasal Insulin on Sympathetic Activity and Cerebral Vasodilation

Conditions
-----------------
Healthy, Vasodilation, Insulin Resistance, Autonomic Dysfunction

Intervention / Treatment
-----------------
* Other: Carbon dioxide breathing
* Other: Neurovascular Coupling
* Drug: Human insulin


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: healthy adult men and women; 18-45 years of age; BMI >18 kg/m2; non-pregnant/non-breastfeeding; non-nicotine users; Exclusion Criteria: taking any medications known to affect metabolic, respiratory, cardiovascular, and/or autonomic Self-reported history of: hepatic, renal, pulmonary, cardiovascular, or neurological disease; stroke or neurovascular disease; bleeding/clotting disorders; sleep apnea or other sleep disorders; diabetes; smoking; history of alcoholism or substance abuse; hypertension; respiratory disease; active cancer; autoimmune disease.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Basic Science
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Insulin<br>Human insulin (160 IU) will be administered as a bolus using an intra-nasal device. | Other: Carbon dioxide breathing<br>* Hypercapnic (5% carbon dioxide) air will be administered before and after intra-nasal insulin exposure.<br>Other: Neurovascular Coupling<br>* Participants will be asked to repeatedly open and close their eyes. With eyes open, participants will focus on a visual image. This will be done before and after intra-nasal insulin exposure.<br>Drug: Human insulin<br>* Participants will be administered human insulin (160 IU) as a bolus using an intra-nasal device.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Amount of muscle sympathetic nerve activity (MSNA) | MSNA burst incidence (bursts/100 heart beats) | Change from baseline at minute 60 | 
| Amount of leg blood flow | Measured with Doppler ultrasound (mL/min) | Change from baseline at minute 60 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Amount of cerebral blood flow | Measured with trans-cranial Doppler ultrasound (cm/s) | Change from baseline at minute 60 |