linjc16/ctgov huggingface dataset:
The Predictive Value of Ureteral Jet Assessment With Ultrasound in Patients Presenting With Acute Renal Colic

Study Overview
=================
Brief Summary
-----------------
This is a single institution, prospective study to evaluate the prognostic significance of renal and bladder ultrasound with ureteral jet assessment and its utility to evaluate the spontaneous stone passage rate of ureteral stones.

Official Title
-----------------
The Predictive Value of Ureteral Jet Assessment With Ultrasound in Patients Presenting With Acute Renal Colic

Conditions
-----------------
Ureteral Calculi

Intervention / Treatment
-----------------
* Device: renal and bladder ultrasound with ureteral jet assessment


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: age 18 and older at the time of consent willing and able to sign consent CT diagnosis of ureteral stone with a stone burden less than or equal to 10mm Exclusion Criteria: obstructed solitary kidney obstructed transplant kidney bilateral obstructed kidneys any condition or reason that, in the opinion of the treating physician, interferes with the patient's ability to participate or places the patient at undue risk.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Study ultrasound<br>Study ultrasound with ureteral jet assessment will be obtained after CT diagnosis of ureteral calculus is made. Ureteral jet data will be documented and patients will be followed prospectively for 42 days for spontaneous stone passage or need for surgical intervention. | Device: renal and bladder ultrasound with ureteral jet assessment<br>* The number of jets from each ureteral orifice will be tabulated over time so that ureteral jet frequency, defined as number of jets per minute, can be calculated. Patients will be categorized into three groups. Group I- no ureteral jets on the symptomatic side; Group II- continuous low-level ureteral jet on the symptomatic side; Group III- ureteral jets similar to nonsymptomatic side.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Time in Days From Diagnosis to Stone Passage. | Number of days that have elapsed from date of diagnosis to date of stone passage or intervention to maximum observation time (42 days). | 42 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The Number of Cases With Concordant Treatment Recommendations Based on the Ultrasound and CT Scan. |  | 42 days | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
stone, ureter, ultrasound
Comparison of Sublingual Misoprostol and Intravenous Oxytocin in Active Management of the Third Stage of Labor

Study Overview
=================
Brief Summary
-----------------
Sublingual misoprostol is superior to oxytocin in reduction of blood loss during the third and fourth stages of labor

Detailed Description
-----------------
Sublingual misoprostol is superior to oxytocin in reduction of blood loss during the third and fourth stages of labor as The data from a pharmacokinetics study suggested that the bioavaiblitiy of misoprostol after sub-lingual administration was higher than those after oral or vaginal administration

Official Title
-----------------
Comparison of Sublingual Misoprostol and Intravenous Oxytocin in Active Management of the Third Stage of Labor

Conditions
-----------------
Postpartum Hemorrhage Prevention by Using Oxytocin Verses Misoprostol

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Women with aheathy singleton pregnancy in spontaneous or induced labor at term . Exclusion Criteria: Hypersensitivity/Contraindication to prostaglandins Antepartum hemorrhage Multiple pregnancy Cardiac disease Malpresentation Rhesus- negative mother hypersensitive disorders Severe anaemia(hemoglobin<7g/dl)

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 40 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| group 1<br>receive 400 Mg sublingual misoprostol. | |
| group 2<br>receive 600 Mg sublingual misoprostol. | |
| group 3<br>receive 5IU of intravenous oxytocin. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| reduce blood loss during third and fourth stages of labor. | reduce blood loss during third and fourth stages of labor by using misopristol is better than using oxytocin | 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the duration of the third stage of labor ,need for oxytocics ,blood transfusion and any adverse effects of the drugs | the duration of the third stage of labor ,needed for oxytocics ,blood transfusion and any adverse effects of the drug will be reduced with mesopristol | 1 year | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
postpartum hemorrhage
Investigation of Early Hormonotherapy Efficacy of Prostate Cancer

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to determine whether early hormonotherapy is effective in the treatment of high risk prostate cancer patients after radical prostatectomy.

Detailed Description
-----------------
The primary purpose of this study is to evaluate the hypothesis, that early administration of adjuvant hormonotherapy (triptorelin) can prolong survival data for high risk patients. Control group (randomised study) will be treated with hormonotherapy, when PSA recidive appear (on demand treatment). Secondary purposes will be to compare PSA dinamics and quality of life data in the groups.

Official Title
-----------------
Investigation of Early Hormonotherapy Efficacy of High Risk Patients for Progression of Prostate Cancer After Radical Prostatectomy

Conditions
-----------------
Prostate Cancer

Intervention / Treatment
-----------------
* Drug: Triptorelin


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: preoperative PSA>20ng/ml postoperative PSA >0.2 ng/ml Gleason > 7 pT3b signated infomed consent Exclusion Criteria: neoadjuvant hormonaltherapy before RP R1 RP N+ RP unstable cncomitant conditions

Ages Eligible for Study
-----------------
Minimum Age: 40 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
Male

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: Triptorelin|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Survival |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| PSA dinamics |  |  | 
| quality of life |  |  | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Prostate cancer
MRI in McArdle Disease (GSDV)

Study Overview
=================
Brief Summary
-----------------
The aim of this study is to describe the degree of muscle wasting in patients with McArdle disease judged by MRI, quantitative magnetic resonance (DIXON) and T1 weighted images, and muscle strength, collected across multiple European sites and compared to healthy controls.

Official Title
-----------------
MRI in McArdle Disease (Glycogen Storage Disease Type V)

Conditions
-----------------
Glycogen Storage Disease Type V

Intervention / Treatment
-----------------
* Diagnostic Test: MRI


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: GSDV or healthy controls Exclusion Criteria: MRI contradictions

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| McArdle disease<br>Glycogen storage disease | Diagnostic Test: MRI<br>* magnetic resonance imaging<br>|
| Healty controls<br>Age and gender matched | Diagnostic Test: MRI<br>* magnetic resonance imaging<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| DIXON MRI | Whole body quantitative muscle fat fraction analyses (DIXON) | 1 time | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Muscle strength | MRC scale | 1 time | 
| T1 MRI | Whole body qualitative muscle fat fraction analyses (T1) | 1 time | 
| Back pain questionnaire | Back pain questionnaire | 1 time |
Natriuretic Peptide's Headache Inducing Characteristics and Effects on the Cerebral Blood Flow

Study Overview
=================
Brief Summary
-----------------
To investigate headache score and accompanying symptoms during and after infusion of the natriuretic peptides.

Official Title
-----------------
Mechanisms and Biological Markers During Headache Induced by Natriuretic Peptides

Conditions
-----------------
Headache, Migraine

Intervention / Treatment
-----------------
* Drug: Natriuretic peptides


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Healthy volunteers Aged 18-40 50-100 kg Fertile women must use safe contraceptives (IUD, oral contraceptives, surgical sterilisation and long lasting gestagen. Exclusion Criteria: Tension type headache more than once/month Other primary headaches Daily medication except contraceptives Drug taken within 4 times the halflife for the specific drug except contraceptives Pregnant or lactating women Exposure to radiation within the last year Headache within the last 24 hours before start of trial Hypertension Hypotension Respiratory or cardiac disease

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 40 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Screening
Allocation: Non-Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Healthy subjects<br> | Drug: Natriuretic peptides<br>* I.V. infusion between 0.2-3 microgram over 20 minutes<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Headache intensity, mean velocity of blood flow in the middle cerebral artery (VmeanMCA), superfical temporal artery diameter, PetCO2, adverse events and vital signs were recorded at T-10, T0 and then every 10 min until 120 min after start of infusion. |  | Every 10 min. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| All subjects were asked to complete a headache diary every hour until 10 h after the discharge. The diary included headache characteristics and accompanying symptoms according to the International Headache Society (IHS 2004) |  | 10 hours after discharge |
Etiological Diagnosis of Urinary Stone in Chinese Children

Study Overview
=================
Brief Summary
-----------------
The incidence of nephrolithiasis in children has been reported to increase by approximately 6-10% annually, and the incidence is currently 50 per 100,000 children with high recurrent rate. Investigators aimed to determine the metabolic risk factors in Chinese children through metabolic evaluation. In order to identify diagnostic criteria of hypocitraturia and hyperoxaluria in western country wether adapt to Chinese children, investigators aim to determine normal urine levels of oxalate and citrate in children without kidney stone.

Detailed Description
-----------------
Investigators aimed to determine the metabolic risk factors in 200 Chinese children with urinary stones through metabolic evaluation. In order to identify diagnostic criteria of hypocitraturia and hyperoxaluria in western country wether adapt to Chinese children, investigators aim to determine normal urine levels of oxalate and citrate in children without kidney stone.

Official Title
-----------------
Etiological Diagnosis of Urinary Stone in Chinese Children

Conditions
-----------------
Urinary Stone

Intervention / Treatment
-----------------
* Other: urinary stone


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Children with urinary stones Exclusion Criteria: Anatomic urinary system abnormality, vesicoureteral reflux, urinary tract infection (temperature >38°C and/or positive urine culture), solitary kidney, and renal insufficiency

Ages Eligible for Study
-----------------
Minimum Age: 1 Year
Maximum Age: 16 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| children with urinary stones<br>children with urinary stones | Other: urinary stone<br>* patients of group one have urinary stones<br>|
| children without urinary stones<br>children without urinary stones | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Urinary oxalate; |  | urine collected in 24 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Urinary citrate; |  | urine collected in 24 hours | 
| Urinary calcium |  | urine collected in 24 hours | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
children, renal stone, metabolic evaluation, Mutational analysis
Pediatric Ilioinguinal / Iliohyogogastric Nerve Block

Study Overview
=================
Brief Summary
-----------------
Ilioinguinal / iliohyogogastric nerve blocks; It is frequently used for analgesia and anesthesia in inguinal region surgeons. However, 95% of these surgeons are under general anesthesia. aim of this study; Intra-operative anesthesia and analgesia effects of ilioinguinal / iliohyogogastric nerve block supported by ketamine sedation only.

Official Title
-----------------
Influence of Ultrasonography Guided Ilioinguinal / Iliohipogastric Block in Intraoperative Anesthesia in Children - Randomized Controlled Study

Conditions
-----------------
Intra-operative Anesthesia and Analgesia Effects

Intervention / Treatment
-----------------
* Drug: ketamine


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: ASA I-II To undergo elective lower abdominal surgery between 2-6 years old Exclusion Criteria: Patients with psychiatric disease Patients whose weight is more than 40 kg Patients with cardiac-pulmonary-neurological disease Patients with bleeding disorder Patients with infection or scar on the injection area Patients with known allergies to local anesthetics

Ages Eligible for Study
-----------------
Minimum Age: 2 Years
Maximum Age: 6 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: block and ketamine<br>Ilioinguinal / iliohypogastric block after ketamine atropine induction and continued with ketamine only in anesthesia | Drug: ketamine<br> <br> |
| Active Comparator: ketamine atropine; laryngeal mask<br>After ketamine atropine induction, a laryngeal mask was inserted and anesthesia administration was continued with 2 sevoflurane MAC and oxygen / air mixture and applied Ilioinguinal / iliohypogastric block. | Drug: ketamine<br> <br> |
| Active Comparator: control group<br>After ketamine atropine induction, a laryngeal mask was inserted and anesthesia administration was continued with 2 sevoflurane MAC and oxygen / air mixture and Non-block, postoperative analgesia with paracetamol IV | Drug: ketamine<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the amount of anesthetic drug which was used |  | nine month | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative visual analogue scale |  | nine month | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Intra-operative anesthesia and analgesia, ilioinguinal / iliohyogogastric nerve block, Pediatric patient
Occludin and Zonulin in Attention-deficit/Hyperactivity Disorder

Study Overview
=================
Brief Summary
-----------------
The association between levels of zonulin and occludin and behavioral/emotional problems in children with ADHD are investigated.

Detailed Description
-----------------
Inclusion criteria for the ADHD group are (a) newly diagnosed ADHD (b) no prior psychotropic treatment for ADHD or any psychiatric disorder (c) age 6-12 years. Exclusion criteria were: (a) history of history of inflammatory/noninflammatory, metabolic, or autoimmune disease (b) any special diet history within the past year (c) use of corticosteroids or regular intake of medication in the last 6 months, (d) body mass index (BMI) [kg/m2] > 30), and (e) cognitive deficits by developmental history.

Official Title
-----------------
Serum Occludin and Zonulin Levels in Attention-deficit/Hyperactivity Disorder

Conditions
-----------------
Attention-deficit/Hyperactivity Disorder

Intervention / Treatment
-----------------
* Diagnostic Test: Zonulin
* Diagnostic Test: Occludin


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: (a) newly diagnosed ADHD (b) no prior psychotropic treatment for ADHD or any psychiatric disorder (c) age 6-12 years. Exclusion Criteria: (a) history of history of inflammatory/noninflammatory, metabolic, or autoimmune disease (b) any special diet history within the past year (c) use of corticosteroids or regular intake of medication in the last 6 months, (d) body mass index (BMI) [kg/m2] > 30), (e) cognitive deficits by developmental history

Ages Eligible for Study
-----------------
Minimum Age: 6 Years
Maximum Age: 12 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: ADHD<br>Children with ADHD | Diagnostic Test: Zonulin<br>* Serum zonulin level<br>Diagnostic Test: Occludin<br>* Serum occludin level<br>|
| Other: Control<br>Children without any psychiatric disorder | Diagnostic Test: Zonulin<br>* Serum zonulin level<br>Diagnostic Test: Occludin<br>* Serum occludin level<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Zonulin level | Serum Zonulin level after psychiatric interview | 1 month | 
| Occludin level | Serum Occludin level after psychiatric interview | 1 month |
Evaluation of an Individualised Written Education Package for Stroke Patients

Study Overview
=================
Brief Summary
-----------------
The primary aim of the randomised controlled trial was to evaluate the effectiveness of a tailored written education package (What you need to know about stroke) on the outcomes of: Knowledge about stroke, self-efficacy, anxiety, depression, perceived health status, satisfaction with the content and presentation of the information received, and desire for additional information for patients following stroke and Knowledge about stroke, self-efficacy, anxiety, depression, satisfaction with the content and presentation of the information received, and desire for additional information for their carers. A secondary aim was to evaluate the effect of written information on the outcomes of knowledge about stroke, self-efficacy, anxiety, depression, and perceived health status of patients following stroke and on knowledge about stroke, self-efficacy, anxiety, and depression of their carers.

Official Title
-----------------
Evaluation of a Computer-Generated Individualised Written Education Package for Patients Following Stroke and Their Carers

Conditions
-----------------
Stroke

Intervention / Treatment
-----------------
* Device: 'What you need to know about stroke' education package


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Had a stroke or transient ischemic attack (TIA) or was the informal carer of a person who had a stroke or TIA; Had a reported English-proficiency level, corrected hearing and vision, and communication status adequate to participate in an interview and complete assessment tasks; Did not have reported or observable dementia; Lived within 50km of the hospital, for ease of follow-up; and Was medically stable.

Ages Eligible for Study
-----------------
Minimum Age: 0 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Educational/Counseling/Training
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Double


Arms and Interventions

| Intervention/Treatment |
| --- |
|Device: 'What you need to know about stroke' education package|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| knowledge about stroke |  |  | 
| self-efficacy |  |  | 
| anxiety |  |  | 
| depression |  |  | 
| perceived health status (patients only) |  |  | 
| satisfaction with the content and presentation of the information received |  |  | 
| desire for additional information |  |  |