Vitamin D Production Levels Achieved by Sunbed Tanning

Study Overview
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Brief Summary
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Health Canada's Radiation Emitting Devices (RED) Act provides exposure time guidelines for sunbed use. These guidelines are intended to protect sunbed users from overexposure to UV radiation. Overexposure is defined as exposure that exceeds the amount needed for vitamin D production and could lead to skin or eye damage. Acute overexposure induces sunburn. However, the effect of the recommended time exposure schedule on serum 25(OH)D response has not been characterized. Further, it is unknown if the maximum time exposures are required to reach and/or maintain optimal 25(OH)D levels. The aim of the current study is to characterize serum 25(OH)D response to regular sunbed use following the time exposure schedule recommended by Health Canada.

Official Title
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The Impact of Health Canada's Sunbed Exposure Time Guidelines on Serum 25(OH)D Concentrations

Conditions
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Healthy

Intervention / Treatment
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* Radiation: Sunbed tanning


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 18 years and older, male or female Exclusion Criteria: History of skin cancer, granulomatous disease, liver disease, or kidney disease Photosensitive medications Pregnancy Vitamin D supplementation within last 60 days Sunbed use within last 60 days Planned travel to sunny destination during study period (January to April 2014)

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Low Pressure 100W sunbed<br> | Radiation: Sunbed tanning<br>* Invention groups undergo a 12-week tanning protocol that follows Health Canada's RED Act<br>|
| Experimental: Low Pressure 160W sunbed<br> | Radiation: Sunbed tanning<br>* Invention groups undergo a 12-week tanning protocol that follows Health Canada's RED Act<br>|
| Experimental: High Pressure sunbed<br> | Radiation: Sunbed tanning<br>* Invention groups undergo a 12-week tanning protocol that follows Health Canada's RED Act<br>|
| No Intervention: Control group<br> | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To characterize serum 25(OH)D response to regular sunbed use, when performed according to the RED Act exposure time guidelines |  | 12 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To characterize serum 25(OH)D response with respect to sunbed lamp output (100W, 160W and High Pressure). |  | 12 weeks | 
| To characterize serum 25(OH)D level with respect to skin lightness. |  | 12 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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the effect of tanning, vitamin D production