Changes in Sensory Perception During Hypnotic Relaxation

Study Overview
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Brief Summary
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Changes in sensory thresholds and pain thresholds will be measured with quantitative sensory testing (QST) before and during hypnotic relaxation in healthy volunteers. Hypnotic susceptibility will be assessed before QST. QST data before and during hypnosis will be compared. Observed sensory changes will be evaluated in relation to the assessed hypnotic susceptibility

Detailed Description
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Healthy volunteers will be recruited and tested regarding their hypnotic susceptibility with Harvard Group Scale. In a second session QST will be performed on the right hand.Then hypnosis will be induced with the fixation method. After that the hypnotherapist will ask them to focus their attention on imagining an individual situation of well-being and calmness the volunteers had described before hypnosis. Then QST will be performed a second time on the same location. Results be compared using student's ttest.

Official Title
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Veränderungen Der Sensibilität Durch Medizinische Hypnose

Conditions
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Healthy

Intervention / Treatment
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* Procedure: Hypnosis


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: healthy volunteers Exclusion Criteria: health conditions of any Kind inability to read and/ or sign informed consent previous hypnosis experience

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years


Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Hypnosis<br>hypnotic induction followed by relaxation and pleasant imagery | Procedure: Hypnosis<br>* hypnotic Relaxation without specific analgesic suggestion<br>* Other names: hypnotic relaxation;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes in Quantitative Sensory Testing | Quantitative Sensory Testing, in detail the following thresholds are included in the testing: Thermal thresholds Cold detection threshold, CDT (°C from baseline 32°C) Warm detection threshold, WDT (°C from baseline 32°C) Thermal sensory limen, TSL (°C) Paradox heat sensation, PHS (x/3) Cold pain threshold, CPT (°C) Heat pain threshold, HPT (°C) Mechanical detection threshold, MDT (mN) Mechanical pain threshold, MPT (mN) Mechanical pain sensitivity, (MPS) Dynamic mechanical allodynia, (DMA) Wind-up, (WUR) Vibration detection threshold, (VDT) (x/8) Pressure pain threshold, (PPT; Pa) | 1 hour | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Observed sensory changes during hypnosis compared to hypnotic susceptibility | The correlation between the obeserved changes as described above and the degree of hypnotic susceptibility | 1 hour |