Placental Membrane for Root Coverage

Study Overview
=================
Brief Summary
-----------------
Aim of the study was to evaluate the clinical efficacy of placental membrane with coronally advanced flap in covering single and multiple Miller's class I and II gingival recession defects.

Detailed Description
-----------------
STUDY DESIGN A total number of 60 teeth in 15 subjects were selected. Patients with bilateral Miller's class I and II gingival recession defects in the maxillary or mandibular anterior and premolar region were selected and divided into two groups using a split mouth design. GroupI (Control) -30 recession defects treated with coronally advanced flap alone, using Zucchelli's technique. Group II (Test) - 30 recession defects treated with coronally advanced flap, using Zucchelli's technique along with placental membrane. . CLINICAL PARAMETERS: Probing Pocket Depth(PPD) Clinical Attachment Level(CAL) Height of Gingival Recession(HGR) Width of Gingival Recession(WGR) Width of Keratinized Gingiva(WKG) The clinical parameters were assessed & recorded on 0 day, 90th day and 180th day

Official Title
-----------------
Treatment of Gingival Recession Using a Coronally Advanced Flap Procedure With or Without Placental Membrane

Conditions
-----------------
Gingival Recession

Intervention / Treatment
-----------------
* Procedure: recession coverage
* Procedure: recession coverage and membrane


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients within the age group 23 to 55 years Bilateral, upper or lower, Miller's class I and Class II gingival recession defects confined to the anterior and premolar region. Presence of identifiable cemento-enamel junction Presence of keratinized tissue apical to the exposed root Exclusion Criteria: Systemic complications Occlusal interferences Any contraindication for periodontal surgery and taking medication which are known to interfere with periodontal tissue health or healing Previous periodontal surgery on the involved site Smokers Pregnant and lactating mothers

Ages Eligible for Study
-----------------
Minimum Age: 23 Years
Maximum Age: 55 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Placebo Comparator: recession coverage<br>30 recession defects treated with Zucchelli's technique. | Procedure: recession coverage<br>* recession coverage done using Zuchellis technique<br>* Other names: root coverage technique;|
| Active Comparator: recession coverage and membrane<br>30 recession defects treated with Zucchelli's technique along with placental membrane. | Procedure: recession coverage and membrane<br>* recession coverage done using Zuchellis technique with placental membrane<br>* Other names: root coverage technique with membrane;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Height of Gingival recession | The height of gingival recession was measured from the cemento-enamel junction to the gingival margin using Williams periodontal probe | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Clinical attachment level | Clinical attachment level is measured as the distance between a fixed point on the crown such as cementoenamel junction to the base of the pocket using williams periodontal probe | Baseline and 6 months | 
| Width of Keratinized Gingiva | It is measured as the distance from the gingival margin to the mucogingival junction using williams periodontal probe | Baseline and 6 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
gingival recession, Zuchellis technique,, placental membrane