Motivational Interviewing to Prevent Suicide in High Risk Veterans

Study Overview
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Brief Summary
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The purpose of study is to test the efficacy of an adaptation of Motivational Interviewing to Address Suicidal Ideation (MI-SI) on the severity of suicidal ideation in psychiatrically hospitalized Veterans at high risk for suicide.

Detailed Description
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Veterans who receive health care from the VA are at elevated risk for suicide, and the number of Veterans at high risk may be growing. Although the months following discharge from psychiatric hospitalization are a period of acute risk for Veterans, there is a dearth of empirically supported treatments tailored to psychiatric inpatients and no studies examining treatments for psychiatrically hospitalized Veterans. This randomized controlled trial will test the efficacy of an adaptation of Motivational Interviewing to Address Suicidal Ideation (MI-SI) on the severity of suicidal ideation in psychiatrically hospitalized Veterans at high risk for suicide. Participants will be recruited from the Acute Psychiatric Inpatient Unit at the Syracuse VA Medical Center. To meet high-risk criteria, Veterans must score over two on the Scale for Suicidal Ideation (SSI), which is prospectively predictive of death by suicide. Participants will complete a screening assessment to confirm eligibility and a baseline assessment of risk factors for suicide. They will be randomized to receive Motivational Interviewing to Address Suicidal Ideation (MI-SI) or a revised version (MI-SI-R) plus treatment as usual (TAU), or TAU alone. The MI-SI groups will receive two sessions of MI-SI during hospitalization and one telephone booster session after discharge. Participants in all conditions will be asked to complete telephone follow-up interviews at 1, 3, and 6 months after discharge. Change in the severity of suicidal ideation will be measured using the SSI.

Official Title
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Motivational Interviewing to Prevent Suicide in High Risk Veterans

Conditions
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Suicidal Ideation, Treatment Engagement

Intervention / Treatment
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* Behavioral: MI-SI+TAU
* Behavioral: MI-SI-R+TAU
* Other: TAU Alone


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Veteran status, admitted to psychiatric inpatient unit, age 18 and over, English speaking, able to understand the study and provide informed consent, clinically cleared to participate by unit staff, receive health care from a VHA facility in upstate New York at increased risk for suicide (Scale for Suicidal Ideation [SSI] > 2) Exclusion Criteria: current psychosis, current mania, dementia, prisoner status, being inaccessible being discharged from the unit less than 48 hours after being identified by study staff

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: MI-SI+TAU<br>Motivational Interviewing to Address Suicidal Ideation | Behavioral: MI-SI+TAU<br>* MI-SI focuses on exploring and resolving ambivalence about living. It consists of 1 or 2 in-person MI-SI sessions (50 mins.) on an inpatient unit, plus a telephone follow-up MI-SI session (30-50 mins)<br>* Other names: Motivational Interviewing to Address Suicidal Ideation;|
| Experimental: MI-SI-R+TAU<br>Motivational Interviewing to Address Suicidal Ideation Revised | Behavioral: MI-SI-R+TAU<br>* MI-SI-R focuses on resolving ambivalence about living. It consists of 1 or 2 in-person MI-SI sessions (50 mins.) on an inpatient unit, plus a telephone follow-up MI-SI session (30-50 mins)<br>* Other names: MI-SI Revised;|
| Other: TAU Alone<br>Treatment as usual | Other: TAU Alone<br>* Inpatient treatment includes medication management, case management, meals and a bed, milieu therapy consisting of creative and social activities, and a safety plan. Some families of veterans also received education to create a supportive home environment. As part of Veterans Health Administration (VHA) suicide prevention policy, the care of suicidal patients is also overseen by a local Suicide Prevention Coordinator and case managers.<br>* Other names: Treatment as usual;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of Participants With Suicidal Ideation | The number of participants with suicidal ideation and severity of suicidal ideation was measured using the Scale for Suicidal Ideation (SSI) at 1, 3, and 6 months after discharge. Scores range from 0-38, with scores of 1 or greater indicating the presence of suicidal ideation. | 6 months | 
| Severity of Suicidal Ideation Among Those With It | Severity of suicidal ideation was measured by the Scale for Suicidal Ideation at 1, 3, and 6 months after discharge. Scores range from 0 to 38, with higher scores indicating more severe suicidal ideation. | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of Participants With Two Outpatient Mental Health or Substance Treatment Sessions | Treatment engagement was measured using the Treatment Services Review-6 (TSR-6) at 1 month after discharge. | 1 month | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Veterans, Motivational Interviewing, Inpatients, Suicide, Attempted