Pain Neuroscience Education in Patients With Fibromyalgia

Study Overview
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Brief Summary
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Many patients with fibromyalgia have little understanding of their condition, leading to maladaptive pain cognitions and coping strategies. Current research has suggested the use of physiotherapy and rehabilitation in addition to cognitive patient education in the treatment of fibromyalgia syndrome. This study aimed to explore the effectiveness of pain neuroscience education in patients with fibromyalgia.

Official Title
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The Effectiveness of Pain Neuroscience Education in Patients With Fibromyalgia

Conditions
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Pain, Chronic, Fibromyalgia

Intervention / Treatment
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* Other: Pain neuroscience education
* Drug: Medical treatment


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: have fibromyalgia as defined by the criteria of the 1990 ACR have Turkish as their native language between 18 and 65 years of age Exclusion Criteria: Having cognitive impairment Receiving psychotherapy Illiterate people Patients with significant hearing loss

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Neuroscience pain education group<br>Pain neuroscience education in addition medical treatment | Other: Pain neuroscience education<br>* A total of 4 NPE (Neuroscience paine education) sessions were held, once each week in addition medical treatment similar to control group. The NPE sessions were conducted by an experienced physiotherapist certified in NPE in face-to-face, group sessions lasting 40-45 minutes. In NPE, the patient is taught about the physiology of pain, central sensitization, representation of the different body regions in the brain, pain-related changes in body perception, and the psychosocial dimensions of pain.<br>Drug: Medical treatment<br>* The patients in control group continued taking their regular gabapentin and pregabalin-derivative drug therapy at the same dosage and duration specified by their physicians.<br>|
| Active Comparator: Control group<br>Medical treatment only | Drug: Medical treatment<br>* The patients in control group continued taking their regular gabapentin and pregabalin-derivative drug therapy at the same dosage and duration specified by their physicians.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Fibromyalgia Impact Questionnaire (FIQ) | The FIQ is an assessment and evaluation instrument developed to measure fibromyalgia (FM) patient status, progress and outcomes | Change from Baseline FIQ at 4th weeks | 
| Pressure pain thresholds (PPT) | Pressure pain thresholds in following five points, 7th cervical vertebra, 3th lumbal vertebra, 5th lumbal vertebra, the belly of calf muscles, and 2nd distal interfalangeal joint were measured using a analog pressure algometer(Baseline, USA). | Change from Baseline PPT at 4th weeks | 
| Tinel's Sign | The Tinel sign is the result of a simple, noninvasive test that checks for nerve problems. The test is positive when a tingling or prickling sensation is felt in the distribution of the Tibial nerve. | Change from Baseline PPT at 4th weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Tampa Scale of Kinesiophobia | The Tampa Scale for Kinesiophobia (TSK) was used for the assessment of kinesiophobia. The TSK is a 17-item questionnaire developed to measure the fear of movement/re-injury. | Change from Baseline PPT at 4th weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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pain neuroscience education, patient education