Computerized Screening, Brief Intervention, and Referral to Treatment in Primary Care

Study Overview
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Brief Summary
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This is a randomized, controlled clinical trial to evaluate the effect of a computerized screening, assessment, and brief intervention on substance use in patients recruited from a primary care clinic. Study participants will be assigned to one of the following 4 study groups: computerized health screening alone (standard care) (SC); computerized assessment-only intervention (CA); computerized assessment followed by a computer-directed motivational intervention (CACI); or computerized assessment followed by a therapist-delivered motivational intervention (CATI). Data regarding substance use, medical and psychosocial functioning, and economic outcomes will be collected. The investigators hypothesize that patients randomized to CACI and CATI will be more likely to report drug abstinence at the 3-month follow-up visit and will show greater reductions in drug use at 1, 3 and 6 months follow-up than patients assigned to CA or SC. Similarly, patients in the CACI and CATI groups will report greater reductions in HIV risk behaviors, lower rates of medical and psychosocial problems, and increased economic gains at the 6-month follow-up. In addition, patients in the assessment only intervention (CA) will have outcomes superior to those found for SC patients. A cost-effectiveness analysis will also be done comparing economic costs associated with CA, CACI and CATI and their relationship to substance use reductions and related improvements in medical and psychosocial outcomes at the 6 month follow-up.

Official Title
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Computer vs Therapist-Delivered Brief Interventions for Substance Use in Primary Care

Conditions
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Substance Use Disorder

Intervention / Treatment
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* Behavioral: Computerized brief intervention
* Behavioral: Computerized health screening
* Behavioral: Computerized assessment
* Behavioral: Therapist-delivered motivational intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 18 - 65 years Primary care clinic patient Exclusion Criteria: Pregnant

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Placebo Comparator: Control<br>Screening only | Behavioral: Computerized health screening<br>* Behavioral intervention<br>|
| Active Comparator: Assessment<br>Screening plus assessment | Behavioral: Computerized health screening<br>* Behavioral intervention<br>Behavioral: Computerized assessment<br>* Behavioral intervention<br>|
| Experimental: Computer Intervention<br>Screening, assessment, and computer-delivered intervention | Behavioral: Computerized brief intervention<br>* Intervention based on Motivational Interviewing technique<br>Behavioral: Computerized health screening<br>* Behavioral intervention<br>Behavioral: Computerized assessment<br>* Behavioral intervention<br>|
| Active Comparator: Therapist Intervention<br>Screening, Assessment, and therapist-delivered intervention | Behavioral: Computerized health screening<br>* Behavioral intervention<br>Behavioral: Computerized assessment<br>* Behavioral intervention<br>Behavioral: Therapist-delivered motivational intervention<br>* Behavioral intervention<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Substance use |  | 3 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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substance use, drug use, drug abuse