Comparing the Prognosis of Patients With Cardia and Non-cardia Gastric Cancer.

Study Overview
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Brief Summary
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To comparing the stage-for-stage prognosis of patients with cardia and non-cardia gastric cancer after operation.

Detailed Description
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The aim of this study is to compare the stage-for-stage prognosis of patients with cardia and non-cardia gastric cancer after operation.In this study, patients with cardiac and non-cardiac gastric cancer who undergo radical resection from January 2019 to December 2024 will be included. We will follow up the patient's progression, recurrence time and survival time.

Official Title
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Comparing the Stage-for-Stage Prognosis of Patients With Cardia and Non-cardia Gastric Cancer After Operation.

Conditions
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Gastric Cancer

Intervention / Treatment
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* Other: Cardia and Non-cardia gastric cancer


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Histopathology or cytopathology proven cardia or non-cardia gastric cancer; Operable gastric cancer patients: primary lesions can be completely excision, no distant metastasis; Life expectancy of at least 6 months; ECOG（Eastern Cooperative Oncology Group ） score 0-1; Age: 18 80 years old; Normal hemodynamic indices before the recruitment (including blood cell count and liver/kidney function). For example: WBC（White blood cell count ）>4.0×109/L; NEU（Neutrophils）>1.5×109/L; PLT（Platelet）>100×109/L; Roughly normal cardiopulmonary function: No coronary heart disease, myocardial infarction, pulmonary heart disease, refractory hypertension; Not concomitant with other uncontrollable benign diseases before the recruitment; Voluntarily signed the informed consent. Exclusion Criteria: Advanced gastric cancer patients with distant metastasis and inoperable ; Pregnant or lactating women; Patients who have no desire to participate in the study.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Cardia gastric cancer<br>Cardiac gastric cancer is defined as a cancer center lies arising 2-5 cm from the gastric mucosa distal to the esophagogastric junction. | Other: Cardia and Non-cardia gastric cancer<br>* We classify gastric cancer into cardia gastric cancer and non-cardia gastric cancer.<br>|
| Non-cardia gastric cancer<br>Non-cardia gastric cancer is defined as tumors originated from the gastric mucosa distal to the cardia. | Other: Cardia and Non-cardia gastric cancer<br>* We classify gastric cancer into cardia gastric cancer and non-cardia gastric cancer.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Disease Free Survival（DFS） | The time from the primary operation to disease recurrence or death. | 5 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Overall survival(OS) | OS is defined as the time from the end of radical surgery to death for any reason or at the last follow-up. | 5 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Cardia gastric cancer, Non-cardia gastric cancer, Resection, Prognosis