Effects of Mindfulness Training on Emotion Regulation and Impulsivity

Study Overview
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Brief Summary
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Mindfulness training has proven to be a reliable treatment for patients with Borderline Personality Disorder (BPD).The present randomized-controlled study examines the effects of mindfulness training on emotion regulation and impulsitivy. In addition, fMRI data was collected pre and post intervention. 70 patients with BPD diagnosis were randomized to either mindfulness or interpersonal effectiveness skills training. Assessments were conucted pre-and-post-intervention.

Official Title
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Effects of Mindfulness Training on Emotion Regulation and Impulsivity

Conditions
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Mindfulness Skills, Interpersonal Effectiveness Skills

Intervention / Treatment
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* Behavioral: Mindfulness skills training
* Behavioral: Interpersonal Effectiveness skills training


Participation Criteria
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Eligibility Criteria
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Inclusion criteria: BPD diagnosis according to two semi -structured interviews: the Structured Clinical Interview for DSM-IV Axis II disorders and the Revised Diagnostic Interview for Borderlines Age between 18 and 50 years old No comorbidities with schizophrenia, drug induced psychosis, organic brain syndrome, substance dependence, bipolar disorder, mental retardation, or major depressive episode in course Not being participating in any other psychotherapy at the moment of the study. Exclusion criteria: • Having participated of skills training in the past.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Mindfulness skills<br> | Behavioral: Mindfulness skills training<br>* Mindfulness skills were taught over a 10-week period. Mindfulness skills were delivered in a weekly group-format. Participants were instructed to follow mindfulness practice at home. The treatment was focused on enhancing the patient capacity to defuse from cognitive and emotional content.<br>|
| Active Comparator: Interpersonal effectiveness skills<br> | Behavioral: Interpersonal Effectiveness skills training<br>* Interpersonal effectiveness skills were taught over a 10-week period. Skills were delivered in a weekly group-format. The treatment was focused on improving interpersonal effectiveness.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Difficulties in Emotion Regulation Scale (DERS) | The DERS is a 28-item-scale that measures difficulties in emotion regulation. Each item has to be rated in a 5-point scale, with higher scores indicating higher difficulties in emotion regulation. | 1-past week | 
| Barrat Impulsiveness Scale (BIS-11) | The current version of the Barratt Impulsiveness Scale is composed of 30 items describing common impulsive or non-impulsive (for reverse scored items) behaviors and preferences. Items are scored on a 4-point-scale, with higher scores indicating higher impulsivity. | 1-past week | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Borderline Symptoms List (BSL-23) | The BSL-23 assess common borderline symptoms during the past week (higher scores indicating higher borderline features). Items have to be rated on a 5-point-scale. | 1-past-week | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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mindfulness, emotion regulation, impulsivity