Clinical Characteristics and Outcome of Patients With COPD With Pneumonia

Study Overview
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Brief Summary
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To identify the clinical characteristics of patients with chronic obstructive pulmonary disease (COPD) combined with community-acquired pneumonia (CAP) and the factors influencing clinical transition.

Detailed Description
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To identify the clinical characteristics of patients with chronic obstructive pulmonary disease (COPD) combined with community-acquired pneumonia (CAP) and the factors influencing clinical transition.Compared to other chronic airway diseases, COPD patients can often have CAP in combination, but there is a lack of comparative studies between COPD patients with CAP and non-COPD patients with CAP.

Official Title
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Study on the Clinical Characteristics and Outcome of Patients With COPD Combined With Pneumonia

Conditions
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Pneumonia, Chronic Obstructive Pulmonary Disease

Intervention / Treatment
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* Other: No inervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: CAP meets the diagnostic criteria published in 2016 Chinese CAP diagnosis and treatment guidelines; CPOPD and AECOPD meet the diagnostic criteria published in Chinese 2013 COPD diagnosis and treatment guidelines; Age ≧ 40years. Exclusion Criteria: age <40years; pregnancy; positive for human immunodeficiency virus (HIV) antibodies; suspected or confirmed tuberculosis or fungal infection of the lung.

Ages Eligible for Study
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Minimum Age: 40 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| COPD combined with CAP inpatients<br>(1) CAP meets the diagnostic criteria published in our 2016 CAP diagnosis and treatment guidelines; CPOPD and AECOPD meet the diagnostic criteria published in our 2013 COPD diagnosis and treatment guidelines; (2) age ≧ 18 years. Exclusion criteria: (1) age <18 years; (2) pregnancy; (3) positive human immunodeficiency virus (HIV) antibody; (4) suspected or confirmed tuberculosis or fungal infection of the lung. | Other: No inervention<br>* No inervention<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| mortality rate | mortality rate | Day 28 from hospitalization | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of days in hospital | Number of days in hospital | through study completion, an average of 1 year | 
| number of days in ICU | number of days in ICU | through study completion, an average of 1 year | 
| number of days on mechanical ventilation | number of days on mechanical ventilation | through study completion, an average of 1 year | 
| cause of using antimicrobial drugs | Days of using antimicrobial drugs during hospitalization | through study completion, an average of 1 year | 
| hospital fees | hospital fees. | through study completion, an average of 1 year |