linjc16/ctgov huggingface dataset:
Intervention Study to Evaluate the Importance of Information Given to Patients With Contact Allergy

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to determine whether extended information given to patients with contact allergy improves knowledge, treatment efficacy and daily functioning.

Official Title
-----------------
Intervention Study to Evaluate the Importance of Information Given to Patients With Contact Allergy

Conditions
-----------------
Dermatitis, Allergic Contact

Intervention / Treatment
-----------------
* Behavioral: extended information


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with suspected contact allergy Age above 18 years Participants have given informed consent Exclusion Criteria: Mental or language disabilities

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: extended information<br>Extended information on specific allergy | Behavioral: extended information<br> <br> |
| No Intervention: Information according to clin. routine<br>Information according to clinical routine | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| knowledge | knowledge about specific contact allergies and exposure, assessed by questionnaire, a modified version of Nordic Occupational Skin Questionnaire NOSQ-2002/Long, and patient records. | one year after inclusion | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| clinical improvement | assessed by questionnaire, a modified version of Nordic Occupational Skin Questionnaire NOSQ-2002/Long, and patient records. | one year after inclusion | 
| quality of life | assessed by questionnaire, Dermatology Life Quality Index (DLQI). | one year after inclusion | 
| effect on daily functioning | assessed by questionnaire, a modified version of Nordic Occupational Skin Questionnaire NOSQ-2002/Long, and Dermatology Life Quality Index (DLQI). | one year after inclusion | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Intervention Studies, Eczema, Randomized Controlled Trial, Knowledge, Quality of Life
Upper-Extremity Bone or Joint Surgery: Long Term Outcome

Study Overview
=================
Brief Summary
-----------------
The specific aim of the study is to obtain long-term follow-up information on patients who have completed their standard clinical care in the Orthopaedic Hand and Upper Extremity Service. The study will help to qualify and quantify long-term recovery and outcomes from uncommon upper extremity fractures, as well as non-fracture bone and joint conditions. The hypotheses vary, but generally focus on the patterns of injury, the results of treatment and the complications encountered.

Official Title
-----------------
Upper-Extremity Bone or Joint Surgery: Long Term Outcome

Conditions
-----------------
Upper Extremity Fractures, Upper Extremity Non-Fracture Bone and Joint Conditions

Intervention / Treatment
-----------------
* Other: 60-minute visit to the outpatient clinic
* Other: Phone Interview


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Subjects with a history of complex arm or leg trauma who have completed their normal care in the Orthopaedic Hand and Upper Extremity Service Exclusion Criteria: Vulnerable populations

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| All subjects<br>Subjects with a history of complex arm trauma | Other: 60-minute visit to the outpatient clinic<br>* An interview, an injury-specific physical exam and/or a set of xrays.<br>Other: Phone Interview<br>* If subject cannot return to office in Boston, researcher may conduct interview over the phone.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Range of Motion | Range of motion of joints measured in degrees with goniometer | 5 years (expected average) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Upper Extremity Function | PROMIS (Patient Reported Outcomes Measurement Information Systems) Upper Extremity Questionnaire | 5 years (expected average) | 
| Pain Interference | PROMIS Pain Interference Questionnaire | 5 years (expected average) | 
| Depression | PROMIS Depression Questionnaire | 5 years (expected average) |
Identification of Novel Targets for Regulation of Adipose Tissue Mass

Study Overview
=================
Brief Summary
-----------------
The aim of this study is to understand the metabolic changes occurring in fat tissue both during controlled weight loss that lead to the improvement of type 2 diabetes and other obesity associated metabolic disorders. The novelty of the study is the analysis of preadipocytes, a poorly characterized subfraction of the adipose tissue, which provides adipocyte precursors and thereby strongly influences adipose tissue mass changes. Knowledge of pathways involved in controlling adipose tissue composition will help to design novel intervention strategies for the treatment of obesity associated metabolic disorders such as type 2 diabetes.

Official Title
-----------------
Identification of Novel Targets for Regulation of Adipose Tissue Mass

Conditions
-----------------
Obesity

Intervention / Treatment
-----------------
* Dietary Supplement: Optifast


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Participants of the OPTIFAST52 program BMI > 30 kg/m2 Exclusion Criteria: Rejection of informed consent by the participant

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Basic Science
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Optifast<br>Patients included take part at a weight reduction program over one year. | Dietary Supplement: Optifast<br>* Formula diet for twelve weeks combined with physical activity and behavioral therapy<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| number of adipocytes and preadipocytes under weight loss |  | three years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| metabolic function of adipocytes and preadipocytes under weight loss |  | three years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
patients with obesity (BMI > 30 kg/m2)
The Effect of Compression Time for Secure Stapling With a Linear Stapler in Laparoscopic Gastric Bypass Surgery

Study Overview
=================
Brief Summary
-----------------
Bleeding from the staple line is a complication of linear stapling. After clamping, a short period after firing of the laparoscopic linear stapler is recommended. That is, the clinician should continue to press the tissue between the prongs of the device to achieve adequate hemostasis at the staple line. The significance of the waiting period for hemostasis at the staple line has not been empirically clarified in humans. In this study, the investigators compared the number of bleeding points use of the laparoscopic linear stapler. Consequently, the investigators assessed the effects of time after the firing of linear stapling in patients who underwent laparoscopic gastric bypass.

Conditions
-----------------
Bleeding of the Staple Line

Intervention / Treatment
-----------------
* Procedure: compression time of the laparoscopic linear stapler


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Clinical diagnosis of morbid obesity Must be laparoscopic surgery Exclusion Criteria: Usage of anti-coagulant Presence of impaired blood clotting

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: No wait<br>Usage of linear stapler without waiting of compression time | Procedure: compression time of the laparoscopic linear stapler<br> <br> |
| Active Comparator: 20 second wait<br>Usage of linear stapler with 20 second compression time | Procedure: compression time of the laparoscopic linear stapler<br> <br> |
| Active Comparator: 60 second wait<br>Usage of linear stapler with 60 second compression time | Procedure: compression time of the laparoscopic linear stapler<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of the bleeding points at the staple line |  | intraoperative |
Dose-Response of Exercise on Long-Term Weight Loss

Study Overview
=================
Brief Summary
-----------------
The purpose is to examine varying durations and intensities of exercise on long-term weight loss.

Official Title
-----------------
Dose-Response of Exercise on Long-Term Weight Loss

Conditions
-----------------
Obesity, Weight Loss

Intervention / Treatment
-----------------
* Behavioral: behavior weight loss


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Female 21-45 years of age BMI = 27-40 kg/m2 Ability to provide informed consent. Ability to provide consent from their personal physician to participate in this study. Exclusion Criteria: Reporting regular exercise participation of at least 20 minutes per day on at least 3 days per week during the previous six months. (This study is designed to recruit relatively sedentary adults.) Diabetes, hypothyroidism, or other medical conditions which would affect energy metabolism. Currently pregnant, pregnant within the previous six months, or planning on becoming pregnant within the next 24 months. (Pregnancy will be based on self-report and will be included on the detailed medical history that is completed by subjects.) Non-medicated resting systolic blood pressure >160 mmHg or non-medicated resting diastolic blood pressure >100 mmHg, or taking medication that would affect blood pressure. Taking medication that would affect resting heart rate or the heart rate response during exercise (e.g., beta blockade). Arrhythmia on resting or exercise electrocardiogram that would indicate that vigorous exercise was contraindicated. History of myocardial infarction or valvular disease. History of orthopedic complications that would prevent optimal participation in the exercise component (e.g., heel spurs, severe arthritis).

Ages Eligible for Study
-----------------
Minimum Age: 21 Years
Maximum Age: 45 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: behavior weight loss|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| weight loss |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| fitness |  |  | 
| dietary intake |  |  | 
| physical activity |  |  | 
| mediators |  |  | 
| body composition |  |  |
Disseminated Endometrial Cancer Cells During Sonohysterography

Study Overview
=================
Brief Summary
-----------------
The purpose of study is to: 1) determine critical volume necessary to overcome tubal pressure and result in fluid dissemination and 2) evaluate functional viability of any disseminated tumor cells collected during SHG

Official Title
-----------------
The Incidence of Disseminated Endometrial Cancer Cells During Sonohysterography and Their Functional Viability: a Prospective Study

Conditions
-----------------
Endometrial Cancer

Intervention / Treatment
-----------------
* Procedure: Sonohysterography


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Stage I endometrial Cancer Disease State IIA endometrial Cancer Disease Exclusion Criteria: Prior tubal ligation Prior bilateral salpingectomy

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Other
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: A<br> | Procedure: Sonohysterography<br>* SHG during surgery for endometrial cancer.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| determine the critical volume necessary to overcome tubal pressure and result in fluid dissemination during SHG |  | during surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| evaluate the functional viability of any disseminated tumor cells collected during SHG |  | during surgery |
Burden of Urinary Incontinence in Home Care Patients in the State of Geneva

Study Overview
=================
Brief Summary
-----------------
Urinary incontinence (UI) is a frequent problem in community-dwelling older adults and has a huge burden on health complications and healthcare costs. Although effective treatments exist, UI is frequently neglected resulting in unmet needs for continence treatment and potential negative health outcomes. The impact of UI in older patients receiving home care services has not been extensively explored. In a recent study we observed that UI was identified in 46% of 699 patients followed by the Fondation des Services d'Aide et de Soins à Domicile in Geneva but the impact of UI on outcome such as institutionalization, hospitalization or death is unknown.

Conditions
-----------------
Urinary Incontinence

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Between July 2004 and December 2004 699 adults patients followed by the Fondation des Services d'Aide et de Soins à Domicile in Geneva (two region in the state of Geneva: Meyrin and St-Jean)
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Continent<br>54% of 699 patients followed as outpatient by the Fondation des Services d'Aide et de Soins à Domicile in Geneva without urinary incontinence | |
| Incontinent<br>46% of 699 patients followed by the Fondation des Services d'Aide et de Soins à Domicile in Geneva and with an urinary incontinence | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Mortality, Patient readmission, Institutionalization
Trials of Ventilation Assisted Substance Elimination Via the Lung - Ethanol (VASEL - Ethanol)

Study Overview
=================
Brief Summary
-----------------
This prospective, randomized control trial will use passive, isocapnic hyperventilation, applied via the ClearMateTM device (Thornhill Medical, Inc) versus controls receiving standard of care supportive management for severe alcohol intoxication to assess for enhanced ethanol elimination kinetics.

Official Title
-----------------
Trials of Ventilation Assisted Substance Elimination Via the Lung - Ethanol (VASEL - Ethanol)

Conditions
-----------------
Alcohol Intoxication

Intervention / Treatment
-----------------
* Device: ClearMateTM


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: intoxicated requiring admission to an emergency unit Exclusion Criteria: Liver or renal disease

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Sequential Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: ClearMate Intervention<br>Participants undergo passive isocapnic hyperventilation via the ClearMateTM device and have regular venous blood samples obtained to measure ethanol clearance kinetics. | Device: ClearMateTM<br>* Passive isocapnic hyperventilation breathing circuit.<br>|
| No Intervention: Supportive Management<br>Participants receive standard of care, supportive management, for alcohol intoxication, having regular venous blood samples obtained to measure ethanol clearance kinetics. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Alcohol elimination time constant | From the recorded venous ethanol blood alcohol values, an elimination time constant will be calculated | 6-24 hours |
Efficacy of a Behavioral Based Education Intervention to Decrease Medication History Errors Among Professional Nurses.

Study Overview
=================
Brief Summary
-----------------
The purpose of the study is to determine if a behavioral knowledge based education intervention will decrease medication transcription errors among professional nurses when admitting elder patients to a hospital. The hypothesis is those professional nurses who receive the behavioral-cognitive eduction medication taking intervention will have fewer medication errors than those professional nurses who do not.

Official Title
-----------------
Efficacy of a Behavioral Based Education Intervention to Decrease Medication History Errors Among Professional Nurses.

Conditions
-----------------
Medication Errors

Intervention / Treatment
-----------------
* Behavioral: cognitive behavioral intervention


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Nurses working 20 hours a week or more Exclusion Criteria: Nurses working less than 20 hours a week Nurse working as a float or pool nurse

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: medication history education<br>Four hospital unit nurses asked to participate in the study. Two nursing units will receive the cognitive behavioral intervention. | Behavioral: cognitive behavioral intervention<br>* The intervention will consist of an hour of cognitive behavioral education. The first 15 minutes spent discussing cases examples of medication errors. The next 15 minutes will include identifying old rules or assumptions nurses have about medication history obtainment. The next 15 minutes will be utilized reviewing a medication tool to be used, and the last 15 minutes will be discussing techniques to help nurse obtain information from elderly patients.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Reduction in medication errors on admission medication history form after intervention |  | 1 year | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Medication history, medication errors, Reduction of admission medication history errors