Retrospective Study of Acute Chest Pain in Extremely Critical Condition for More Than Ten Years

Study Overview
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Brief Summary
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Acute non-traumatic chest pain is a common kind of symptom in extremely critical condition, with various pathogenesis and different level of risk . Chest pain in high risk takes 1/3 of that. It mainly includes acute coronary syndrome (including myocardial infarction and unstable angina pectoris, accounted for over 95% of chest pain in high risk), aortic dissection, pulmonary embolism etc, and is in high lethality and deformity. The investigators do the research : To study the diagnosis and management condition of acute chest pain in extremely critical condition for last ten or more years in Qilu Hospital,Shandong University. To discuss the significance of key accompanying symptoms(for example radiating pain, chest distress, sweating, nausea etc), physical signs and lab examination in early diagnosis and risk stratification of acute chest pain in extremely critical condition. To study the effect factors of thrombus burden in STEMI patients, at the same time, creat a a simple, practical and scientific method of blood clots classification.

Official Title
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Retrospective Study of Acute Chest Pain in Extremely Critical Condition for More Than Ten Years

Conditions
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Acute Myocardial Infarction, Pulmonary Embolism, Aortic Dissection

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Inpatients of Qilu Hospital, whose electronic medical records were searched out by terms of acute myocardial infarction, aortic dissection, pulmonary embolism and unstable angina in International Classification of Diseases(ICD)-10 code from Jan.2003 to Sep.2015. Exclusion Criteria: Patients whose medical records are false, omitted or uncompleted because of transference, death et al.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Diagnosis and management of acute chest pain diseases in extremely critical condition | In-hospital mortality, hospitalization days | A week after data collected | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Clinical characteristics of participants for demographics, medical history, examination results and investigations retrieved from electronic medical records | Frequency of chest pain, sweating, nausea, radiating pain, dyspnea and temperature, pulse, respiration rates, blood pressure, value of blood glucose, D-Dimer, et al, on admission. | A week after data collected | 
| The predicted factors of thrombus burden in STEMI patients, and the influence of thrombus burden on mortality | The relationship between value of leukocyte,glucose,lipid,blood pressure et al, all-cause mortality and thrombus burden. | A week after data collected | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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retrospective study, acute myocardial infarction, acute aortic dissection, pulmonary embolism, unstable angina