linjc16/ctgov huggingface dataset:
Feasibility and Validity of Remote Lung Function Assessment

Study Overview
=================
Brief Summary
-----------------
Comparison of standard spirometry to non invasive remote lung function measures of chest wall movement using depth camera technology.

Detailed Description
-----------------
This study plans to test a new non invasive way of measuring lung function and compare it to the current method of blowing into a spirometer. Spirometry is an essential investigation for diagnosis and assessment of severity in people with Chronic Obstructive Pulmonary Disease (COPD) and other respiratory conditions, it is used in every respiratory unit and across primary care. It requires subjects to blow into a tube which measures volume and flow of expired air. It involves specialist equipment and training to perform and interpret. Not all patients are capable of performing spirometry, in particular children, frail, cognitively impaired and those experiencing a flare or exacerbation of symptoms. Remote lung function assessment technology has the potential to enable assessment of lung function in these groups of patients. In the future it is also hoped that it could be used to improve respiratory disease monitoring outside the healthcare environment such as in the patients home. This new method uses the latest infra-red depth detection cameras to measure chest wall movement. (N.B this does not capture identifiable images). We would like to record participants chest wall movements while blowing into the spirometer.

Official Title
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Comparison of Remote Camera Measures of Lung Function Compared to Standard Spirometry

Conditions
-----------------
Chronic Lung Disease

Intervention / Treatment
-----------------
* Device: Kinnect 3 camera


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients attending outpatient department in respiratory medicine. Scheduled to undergo spirometry - Exclusion Criteria: Unable to give informed consent Unable to perform spirometry -

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Device: Kinnect 3 camera|comparison of Kinnect 3 measures of chest wall movement during standard spirometry|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Correlation between change in chest wall depth and Forced Expiratory Volume in 1 second (FEV1) | Change in lung volume over time (litre per minute) | participants will be followed up for the duration of outpatient visit - on average 3 hours |
Effects of IMT on Clinical Outcomes in Cardiac Surgery

Study Overview
=================
Brief Summary
-----------------
Individuals who underwent cardiac surgery may experience anesthesia, intracardiac operation, cardiopulmonary bypass and mechanical ventilation, which will result in a lot of injuries. Inspiratory Muscle Training (IMT) is a regimen of breathing exercises that aim to strengthen the respiratory muscles and make it easier for a person to breathe. The aim of this study was to evaluate the efficacy of preoperative IMT on e clinical outcomes in patients with cardiac surgery.

Official Title
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Effects of Inspiratory Muscle Training on Clinical Outcomes in Individuals With Cardiac Surgery: A Randomized Controlled Trial

Conditions
-----------------
Cardiovascular Disease

Intervention / Treatment
-----------------
* Device: Inspiratory Muscle Training


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Adult men and women Elective cardiac surgery Cardiac surgery on cardiopulmonary bypass Exclusion Criteria: Individuals with neurological diseases that may make it impossible to perform IMT Emergency cardiac surgery Cardiac surgery without cardiopulmonary bypass

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 90 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Inspiratory Muscle Training<br>The Inspiratory Muscle Training group received respiratory muscle training, in addition to routine preparation, including laboratory and radiological examinations and preoperative education. | Device: Inspiratory Muscle Training<br>* IMT underwent 5 days of 30 breaths twice daily at 50% (+5% increase each week) of maximum inspiratory pressure (MIP)<br>|
| No Intervention: Control<br>The control group received routine preparation, including laboratory and radiological examinations and preoperative education. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative intubation time |  | 5 days after surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative length of stay |  | 30 days after surgery |
Relationship Between Level of GPCR Autoantibodies and Cardiac Structure & Funtions Based on UCG and CMR

Study Overview
=================
Brief Summary
-----------------
This study is a prospective cohort study，we want to observe the changes of different cardiovascular antibody levels in STEMI patients undergoing emergency PCI;and combined with different cardiovascular antibody levels and various indicators, evaluate the impact of ischemia-reperfusion injury and prognosis in STEMI patients after emergency PCI.

Detailed Description
-----------------
This study mainly observed the changes of different cardiovascular antibody levels in STEMI patients undergoing emergency PCI by measuring autoantibodies; and the changes of autoantibodies in STEMI patients compared with coronary angiography-negative patients. At the same time, combined with different cardiovascular antibody levels and various indicators, the effect of ischemia-reperfusion injury and prognosis after emergency PCI in STEMI patients was evaluated. The correlation between autoantibody changes and imaging indicators in STEMI patients was evaluated by cardiac color Doppler ultrasound and CMR.

Official Title
-----------------
Relationship Between Level of GPCR Autoantibodies and Cardiac Structure & Funtions Based on UCG and CMR

Conditions
-----------------
STEMI

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: STEMI patients meet the diagnostic criteria of Guidelines for the Diagnosis and Treatment of Acute ST-segment Elevation Myocardial Infarction (2015); ②STMEI patients undergoing emergency PCI should undergo emergency PCI within 12 hours of onset at Beijing Friendship Hospital affiliated to Capital Medical University; ③ The selected patients were able to complete the MRI and STE examinations; ④ They agreed to be enrolled in the trial and signed the informed consent. Exclusion Criteria: Past myocardial infarction or revascularization (PCI or CABG); ②Congestive heart failure LVEF<40%; ③Atrial fibrillation; ④Renal insufficiency (GFR<30 ml/min); disease; ⑥ rheumatic immune system disease; ⑦ malignant tumor; ⑧ claustrophobia; ⑨ contraindication to CMR;
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| β1-AA, β2-AA, α1-AA, M2-AA and AT1-AA OD values | About 10ml of venous blood was collected on the second day of admission, serum was separated, and the OD values of β1-AA, β2-AA, α1-AA, M2-AA and AT1-AA were detected by ELISA. | Admission Baseline | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
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STEMI, GPCR, PCI
Heart Rate, Baroreflex Sensitivity and Cardiovascular Morbidity and Mortality in the Population

Study Overview
=================
Brief Summary
-----------------
The aim of the present PPS3 study is (1) to assess the determinants of the regulation of heart rate and blood pressure variations and carotid properties (under different physiologic stimulations) and (2) to evaluate the respective contribution of heart rate, blood pressure variations and carotid properties to cardiovascular morbidity and mortality including sudden death during 10 years at least in healthy considered subjects.

Detailed Description
-----------------
Overall, 10 000 men and women will be recruited during two years for an extensive clinical examination including a 2h holter ECG, a carotid doppler echo tracking, a step test, as well as blood and DNA collections. Thereafter, the cardiovascular morbidity and mortality of the participants will be followed up for 10 years at least.

Official Title
-----------------
Heart Rate, Baroreflex Sensitivity and Cardiovascular Morbidity and Mortality in the Population. The Paris Prospective Study III

Conditions
-----------------
Community Based Study, Cardiovascular Disease, Sudden Death, Blood Pressure

Intervention / Treatment
-----------------
* Other: Spider flash EKG, echocardiography tracking, step test


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 50-75 years, French speaking, given consent for genetic analysis, written consent for participating in the study Exclusion Criteria: <50 years and >75 years, no French speaking, current pregnancy, chronic severe disease, disagreement for genetic analysis, step test considered as non possible or non advisable by medical decision.

Ages Eligible for Study
-----------------
Minimum Age: 50 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| general population<br>Observational study of 10000 adult men and women from the general population who benefited from a free extensive health check up in Paris, France | Other: Spider flash EKG, echocardiography tracking, step test<br>* cardiac rhythm recorded during health check up, echocardiography tracking of the right common carotid, step test during 2 minutes<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| cardiovascular disease |  | after 10 years of follow up | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| heart rate parameters and baroreflex sensitivity |  | after 2 years of recruitment | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
epidemiology, risk factors, heart rate, baroreflex sensitivity, sudden death
Analysis of Patient Understanding of Radiation Therapy Among Patients With Breast Cancer

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to conduct a descriptive feasibility study of assessing how patients retain and understand information regarding radiation therapy obtained from an initial consult visit. This study will also pilot the use of visual aids and assess their utility to patients during a consult. The study will provide a baseline to conduct larger studies that will later incorporate additional patient education tools to assess changes in patient understanding of information received in radiation oncology patient consultations.

Official Title
-----------------
Analysis of Patient Understanding of Radiation Therapy Among Patients With Breast Cancer

Conditions
-----------------
Breast Cancer

Intervention / Treatment
-----------------
* Behavioral: Survey questionnaire


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients 18 years or older with non-invasive or invasive breast cancer receiving consultation at the breast radiation oncology clinic for radiotherapy recommendations Exclusion Criteria: Patients under 18 years old or receiving palliative care

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Supportive Care
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Patients Who are Anticipated to Receive Definitive Treatment<br> | Behavioral: Survey questionnaire<br>* The survey questionnaire will include semi-structured questions about patient demographics and patient understanding of the risks and benefits of radiation, different treatment options, the treatment process, utility of visual aid presentation and information gathering preference using a semi-structured questionnaire<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| post-consultation telephone questionnaire | assess patient understanding and use of visual aids specifically in radiation oncology consultations | 10 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| correlations between patient survey score as a measure of patient understanding | Patients will also be asked to rate the ease of understanding of visual aids provided and their utility in facilitating patient understanding of radiation oncology concepts. It will be analyzed via ANOVA to investigate the association of various factors to the patient's total score. Each participant's interview will be scored based on the following scoring system: Correct=1point; Incorrect = 0 point. | 10 days following consultation |
Inflammatory Bowel Disease Registry in Daegu-Gyeongbuk

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to investigate the incidence and natural course of inflammatory bowel disease in the southeastern area of Korea.

Official Title
-----------------
Observational Study Using Inflammatory Bowel Disease Registry in Daegu-Gyeongbuk, Southeastern Area of Korea

Conditions
-----------------
Idiopathic Chronic Inflammatory Bowel Disease

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Clinical diagnosis of inflammatory bowel disease including Crohn's disease and ulcerative colitis Followed up for at least 6 months for the correct diagnosis Exclusion Criteria: Patients who do not live in Daegu-Gyeongbuk province
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| inflammatory bowel disease<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| All newly diagnosed cases | In one year, all inflammatory bowel disease including Crohn's disease and ulcerative colitis which is newly diagnosed in Daegu-Gyeongbuk province of Korea is recorded. | one year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| All operation cases | For one year, all patients who have surgical managements for IBD are counted. | one year | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
inflammatory bowel disease, registry, incidence, Korea
Comparison of Fluid Requirements in Pancreatectomy: Laparotomy vs. Laparoscopy

Study Overview
=================
Brief Summary
-----------------
In this retrospective cohort study, the investigators reviewed and analyzed the electronic medical records of consecutive patients who underwent distal pancreatectomy either via laparotomy or laparoscopy. Intraoperative fluid administration amount, postoperative complications, length of hospital stay, and readmission rate were evaluated. The total fluid amounts were calculated using the sum of colloids multiplied by 1.5 or 2.0 and crystalloids.

Detailed Description
-----------------
There has been recent progress in intraoperative fluid therapy. However, little is known about intraoperative fluid therapy in laparoscopic surgery. The purpose of this study is to determine whether there are differences in the basal fluid requirements during surgery between laparotomy and laparoscopic distal pancreatectomy. This study analyzed the records between June 2006 and March 2016. And 253 patients who underwent distal pancreatectomy via either laparotomy (73 patients) or laparoscopy (180 patients). This study was based on a retrospective review and analysis of the electronic medical records. The volume of intraoperative fluid administered, postoperative complications, length of hospital stay, and readmission rate were evaluated. The total volume of fluids was calculated as the sum of the volume of crystalloid plus the volume of colloid multiplied by 1.5 or 2.0.

Official Title
-----------------
Comparison of Intraoperative Basal Fluid Requirements in Distal Pancreatectomy - Laparotomy vs. Laparoscopy: A Retrospective Cohort Study

Conditions
-----------------
Pancreatectomy, Fluid Therapy, Laparoscopy

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: indication of distal pancreatectomy Exclusion Criteria: transfusion ASA physical status over 4 co-operate other surgery

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Open<br>Patients underwent open distal pancreatectomy | |
| Laparoscopic<br>Patients underwent laparoscopic distal pancreatectomy | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| intraoperatively administered fluid amounts |  | one year | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Fluid Therapy, Laparoscopy
Visual Stimulus and Eye Movement

Study Overview
=================
Brief Summary
-----------------
This study is designed to understand how we see visual patterns and how these patterns lead to eye movements. Normal volunteers participating in this study face a screen on which spots or patterns of light are projected. They are asked to respond to the patterns by voice, eye movements or hand movements. Eye and lid movements are recorded in one of the following ways: Electro-oculogram < small disc electrodes taped to the skin near each eye measure the eye movements as the eyes change position. Infrared detector < an infrared beam is reflected off the eye and picked up by detectors that record the eye movements. Contact lens ring < a smooth plastic ring is placed on the white of the eye surrounding the cornea and eye position is measured using a magnetic coil. Study sessions last less than four hours.

Detailed Description
-----------------
The purpose of this protocol is to study the physiology of the visuo-motor system in normal humans. This will be accomplished by recording eye movements and other responses (such as reaction time to bar press or verbal responses) to differing stimuli. The stimuli will be primarily visual but may include auditory or tactile stimuli.

Official Title
-----------------
Visual Motor Coordination in Man

Conditions
-----------------
Healthy

Participation Criteria
=================
Eligibility Criteria
-----------------
INCLUSION CRITERIA: Normal adult volunteers age 18 and over are included. Only normal volunteers are studied under this protocol. Normal volunteers are recruited from the NIH volunteer office and the NIH web page. Women and minorities are actively recruited.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 59 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Vision, Eye Movement, Perception, Healthy Volunteer
Continuous Regional Anesthesia for Septic Limb Orthopedic Surgery

Study Overview
=================
Brief Summary
-----------------
This study aims to assess the safety of using continuous regional anesthesia for post-operative analgesia during septic limb orthopedic surgery. The study hypothesis is that continuous regional anesthesia would not induce septic complication in the operated limb and could improve post-operative recovery.

Official Title
-----------------
Continuous Regional Anesthesia for Septic Limb Orthopedic Surgery

Conditions
-----------------
Osteo Arthritis, Cellulitis

Intervention / Treatment
-----------------
* Drug: Systemic analgesia + Continuous regional anesthesia
* Drug: Systemic analgesia


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Osteo arthritis or cellulitis requiring surgical intervention anatomical possibility of regional anesthesia age >18 ans written informed consent Exclusion Criteria: loco-regional anesthesia impossibility (puncture zone infection, local anesthesics allergie, amiodarone or mexilétine treatment, neurologic deficit for exemple) patient under tutelle or curatelle pregnant or beast feeding woman

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Continuous regional anesthesia<br> | Drug: Systemic analgesia + Continuous regional anesthesia<br>* Systemic analgesia + Continuous regional anesthesia, peri neural for the 2 to 4 first days post-operative<br>|
| Active Comparator: Systemic analgesia<br> | Drug: Systemic analgesia<br>* Systemic analgesia as usual<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Septic complication in the operated limb | Septic complication in the operated limb Pain score Nausea and vomiting | 28 days |