Apical Patency and Postoperative Pain.

Study Overview
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Brief Summary
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The purpose of this study is to determine whether maintaining an apical patency causes postoperative pain in posterior teeth with necrotic pulp and apical periodontitis.

Detailed Description
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Apical patency (AP) is a procedure that prevents accumulation of soft and hard tissue debris within the cement canal. However, some RCTs indicate that maintaining an AP causes postoperative pain, whilst some RCTs pointed out there is no difference in terms of pain when AP has been performed. We, therefore, would like to conduct a RCT to increase the sample size of the previously performed RCTs to do an systematic review.

Official Title
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Influence of Maintaining Apical Patency on Postoperative Pain in Posterior Teeth With Necrotic Pulp and Apical Periodontitis: A Randomized Controlled Trial.

Conditions
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Pain Postoperative

Intervention / Treatment
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* Procedure: APICAL PATENCY


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Mature permanent teeth having plural necrosis and apical periodontitis Exclusion Criteria: Systemic disorders Diabetes Pregnancy Less than 18 years of age Immunocompromised Patients who had taken antibiotics in the past 1 month Patients who had a positive history of analgesic use within the past 3 days Previously accessed teeth

Ages Eligible for Study
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Minimum Age: 21 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Intervention<br>Endodontic treatment was performed in posterior teeth with necrotic pulp and periapical periodontitis using a reciprocating single-file system (Reciproc). Local anesthesia was provided (2% Novocaine with 1:80,000 epinephrine), isolation with rubber dam and standard access cavity preparation was done.Using 2.5 % sodium hypochlorite, canal negotiation was done & apical patency was achieved with #10 K-files in patency group after determining working length. Coronal flaring with # 2 and #3 Gates-Glidden drills was done. The canals were obturated with gutta-percha and epoxy resin sealer. The treatments were carried out in one-visit. | Procedure: APICAL PATENCY<br>* After determining the working length, a small and flexible size 10 K-file was inserted 1 mm beyond the WL.<br>|
| No Intervention: Control<br>In the control group, apical patency did not maintained. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 100-mm Visual Analog Scale (VAS). | Pain severity was evaluated as no pain (0-4 mm), mild pain (5-44 mm), moderate pain (45-74 mm) and severe pain (75-100 mm). | 7 days. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The number of patients taking an analgesic following the endodontic treatment. | The patients were asked to take an analgesic in the 7 days of time frame. | 7 days. | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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apical patency, root canal treatment