Relationship Between Fertility Hormone Patterns and Pregnancy Rates.

Study Overview
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Brief Summary
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The purpose of this study is to determine if certain patterns of hormone levels during the menstrual cycle are correlated with different pregnancy outcomes.

Detailed Description
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Proov tests are fertility tracking tests. They are used for monitoring ovulation at home, and are able to measure one or more hormones. These hormones can predict and confirm ovulation. Tracking these hormones can help a woman understand if she is ovulating, and can help to identify problems that could be preventing pregnancy. After giving permission to access your testing history collected in the Proov app from March 2020 to April 2022, you will complete an online survey about your fertility test results and pregnancy status. You will also be asked information regarding your age, race, smoking status, and BMI. Your test results logged in the Proov app will be shared automatically. You will need 10-20 minutes to fill out the fertility survey.

Official Title
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Relationship Between Fertility Hormone Patterns and Pregnancy Rates.

Conditions
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Pregnancy Related, Hormone Deficiency

Intervention / Treatment
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* Diagnostic Test: Proov Test


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Female Age 18 - no limit Have completed one full cycle using the Proov app Exclusion Criteria: Male Have not completed one full cycle using the Proov app

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Proov test strip users that record results with the Proov app<br>Participants using Proov test strips along with the Proov app who have logged at least one complete cycle will be asked to complete an online survey about fertility test results and current/previous pregnancy status. They will also be asked cycle history (irregular vs regular, cycle length), fertility testing (partners semen analysis results, AMH level, HSG results), possible fertility medications taken or prescribed, age, race, smoking status, and BMI. | Diagnostic Test: Proov Test<br>* Rapid response urine PdG and LH test strips, Proov<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| self reported pregnancy | Questionnaire used to assess if positive Proov test strips measuring urine PDG correlate with increased rates of self reported pregnancy | Two menstrual cycle, up to 45 days each | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| self reported first trimester pregnancy loss | Questionnaire used to assess if negative Proov test strips measuring urine PDG correlate with increased rates of self reported first trimester pregnancy loss | Three months |