Monitoring of Regional Lung Ventilation by Chest Electrical Impedance in the Course of Extubation

Study Overview
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Brief Summary
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The Electrical Impedance Tomography (EIT) is a non-invasive exam. This exam performed on the lung continuously produces cross-sectional images of lung function. It may be relevant in lung description.

Detailed Description
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The aim is to follow the patients after extubation for the lung description. EIT exam is performed before extubation, during follow-up visits and 48H after extubation

Official Title
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Monitoring of Regional Lung Ventilation by Chest Electrical Impedance in the Course of Extubation

Conditions
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Respiratory Disease

Intervention / Treatment
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* Device: EIT


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age> 65 years Invasive mechanical ventilation time greater than 48 hours known or suspected Chronic obstructive pulmonary disease Known or suspected heart failure Success in the spontaneous ventilation and extubation test scheduled by the doctor in charge Patient or trusted person who has been informed of the study and has consented to participate Exclusion Criteria: Pregnant women, minor patients Patients under extracorporeal circulatory assistance (ECMO) Refusal of the patient Contraindications to the realization of the phrenic nerve stimulation technique: Pacemaker, implantable cardiac defibrillator and other pacemakers Spinal implants, thoracic drains ... Copper allergy Epileptic patients Patients performing uncontrolled body movements Contraindications to the realization of the technique of Electrical Imaging Tomography: Breast circumference not between 70 cm and 150 cm. Body mass index (BMI) greater than 50 Impossibility of placing the CT belt at the level of the chest skin (lesions, bandages, dressings, chest drains ...) Patients with unstable spinal lesions or fractures Allergy to tomography belt materials: silicone, brass, stainless steel Pacemaker, implantable cardiac defibrillator and other pacemakers Patients under legal protection (tutorship / guardianship)

Ages Eligible for Study
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Minimum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Intervention Model: Single Group Assignment
Interventional Model Description: No-randomized,no-comparative study
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: EIT<br>Electrical Impedance Tomography is performed before extubation, during follow up visits of extubation and 48H after extubation | Device: EIT<br>* Electrical Impedance Tomography is performed before extubation, during follow-up visits of extubation and 48H after extubation. Follow-up visits are shortened in case of extubation failure.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| acute respiratory failure | Occurrence of extubation failure | 48 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| pulmonary ventilation | lung pulmonary volume (cm) | 48 hours |