Compliance to Ophthalmic Follow-up Examinations and Surgical Outcome for Proliferative Diabetic Retinopathy

Study Overview
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Brief Summary
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The relationship between the surgical outcome of vitreous surgery for proliferative diabetic retinopathy and the compliance to ophthalmic follow-up examinations was evaluated.

Detailed Description
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The medical records of 94 patients that had undergone vitreous surgery for proliferative diabetic retinopathy (PDR) and were followed for at least 6 months were reviewed. The subjects were divided into three groups; the never-treated group consisting of patients who had no previous ophthalmic examination until the first visit when vitreous surgery was prescribed; the non-compliant group consisting of patients with a history of missing ophthalmic examination over a one year period, and the compliant group consisting of patients who had ophthalmic examinations at least once a year. The evaluations included age, gender, plasma level of glycosylated hemoglobin (HbA1c) at the preoperative examination, presence of preoperative panretinal photocoagulation, preoperative best-corrected visual acuity (BCVA), postoperative BCVA at the final examination, status of the PDR, the numbers of vitreous surgeries, and presence of pre- and postoperative neovascular glaucoma.

Official Title
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Compliance to Ophthalmic Follow-up Examinations Affect Outcome of Vitrectomy for Proliferative Diabetic Retinopathy

Conditions
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Proliferative Diabetic Retinopathy

Intervention / Treatment
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* Procedure: Vitrectomy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: One hundred and twenty-eight eyes of 94 patients that had undergone vitreous surgery for proliferative diabetic retinopathy. Type 2 diabetes. Exclusion Criteria: The patients were not followed more than 6 months.
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Never-treated group<br>The patients who had no previous ophthalmic examination until the first visit when vitreous surgery was prescribed | Procedure: Vitrectomy<br>* Vitrectomy. Diabetic retinopathy<br>* Other names: Compliance of follow-up;|
| The non-compliant group<br>The patients with a history of missing ophthalmic examination over a one year period | Procedure: Vitrectomy<br>* Vitrectomy. Diabetic retinopathy<br>* Other names: Compliance of follow-up;|
| The compliant group<br>The patients who had ophthalmic examinations at least once a year | Procedure: Vitrectomy<br>* Vitrectomy. Diabetic retinopathy<br>* Other names: Compliance of follow-up;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Preoperative status | Plasma level of glycosylated hemoglobin (HbA1c) | Preoperative period | 
| Preoperative status | Best-corrected visual acuity (BCVA), | Preoperative period | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative status | Postoperative best-corrected visual acuity (BCVA) at 6 months and the final examination | up to 1 year | 
| Postoperative status | Status of the proliferative diabetic retinopathy | up to 1 year | 
| Postoperative status | Presence of neovascular glaucoma. | up to 1 year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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periodic examinations, compliance