Fluid Dairy Products Consumed Before and Within a Pizza Meal on Glycemic Response, Food Intake and Satiety in Children

Study Overview
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Brief Summary
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The purpose of this study is to examine the effects of fluid dairy products on blood glucose and insulin, satiety and energy intake in normal weight and overweight/obese children in the age range of 9-14 y. Experiment 1: The specific objective is to examine the effects of isocaloric and isovolumetric amounts of 2% M.F. milk, 1% M.F. chocolate milk, 1.5% M.F. yogurt drink, tropical punch and water consumed before and within a pizza meal 60 min later on appetite and food intake. Experiment 2 will compare the effects of 2% M.F. milk and tropical punch consumed before and with a pizza meal 60 min later on food intake, blood glucose, and appetite hormone response.

Official Title
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The Effect of Fluid Dairy Products Consumed Before and Within a Pizza Meal on Glycemic Regulation, Food Intake and Satiety in Normal Weight and Overweight/Obese Children

Conditions
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Diabetes Prevention, Obesity Prevention

Intervention / Treatment
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* Other: Dietary Intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Healthy Born at term Exclusion Criteria: Diabetes Medications Lactose-intolerance or allergies to milk Breakfast skippers and those on an energy restricted diet

Ages Eligible for Study
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Minimum Age: 9 Years
Maximum Age: 14 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 2% M.F. Milk<br>Dietary treatment: 2% m.f. milk | Other: Dietary Intervention<br> <br> |
| Experimental: 1% M.F. Chocolate Milk<br>Dietary treatment: 1% m.f. chocolate milk | Other: Dietary Intervention<br> <br> |
| Experimental: 1.5% M.F. Drinkable Yogurt<br>Dietary treatment: 1.5% m.f. drinkable yogurt | Other: Dietary Intervention<br> <br> |
| Experimental: Tropical Punch<br>Dietary treatment: fruit-flavoured beverage | Other: Dietary Intervention<br> <br> |
| Experimental: Water<br>Dietary treatment: calorie-free control | Other: Dietary Intervention<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Food intake | The amount of food (grams) and energy (kcal) consumed ad libidum with the test meal. | 60 minute | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Blood glucose |  | 0, 30, 60, 85, 115, and 145 minute | 
| Appetite hormones | Insulin, total ghrelin, glucagon-like peptide-1, and peptide YY | 0, 30, 60, 85, 115, and 145 minute | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Food intake, Appetite, Blood glucose, Insulin, Dairy, Milk