Mini-autogenous Skin Grafts With Skin Homografts Versus Autogenous Skin Graft for Covering Post Burn Wounds in Children

Study Overview
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Brief Summary
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A prospective study comparing the use of mini-autogenous skin grafts and skin homograft versus autogenous skin grafts for covering post burn wounds in children.

Detailed Description
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A prospective study comparing the use of mini-autogenous skin grafts and skin homograft versus autogenous skin grafts for covering post burn wounds in children so that the patient can continue on his/her normal life early with less deformities

Official Title
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Mini-autogenous Skin Grafts With Skin Homografts Versus Autogenous Skin Graft for Covering Post Burn Wounds in Children

Conditions
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Burns

Intervention / Treatment
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* Procedure: Mini autogenous skin graft


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: This study will include children (3-12) years old with (10-30) % body surface area burns, admitted to Assuit university hospital burn unit. The raw areas in both upper and lower limbs will be the site of the study. Exclusion Criteria: Patients younger than 3 years old. Patients with burns more than 30% of total body surface area. Patients with medical or mental diseases.

Ages Eligible for Study
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Minimum Age: 3 Years
Maximum Age: 12 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Mini autogenous skin grafts<br>we take the autogenous skin graft from the same patient then cut it into small pieces then we spread it over the burn wound on one limb then cover these small pieces with homogenous skin graft taken from another person. | Procedure: Mini autogenous skin graft<br>* mini-autogenous skin grafts and skin homograft versus autogenous skin grafts for covering post burn wounds in children.<br>|
| Active Comparator: Autogenous skin graft<br>we take the regular autogenous one piece skin graft from the same patient and cover the burn wound on the other limb then we make a comparison between both limbs | Procedure: Mini autogenous skin graft<br>* mini-autogenous skin grafts and skin homograft versus autogenous skin grafts for covering post burn wounds in children.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The major outcome is to specify if the regular single piece autogenous skin graft is better than the new technique that uses small pieces mini autogenous skin grafts for treatment of post burn wounds in children. or vice versa? | the spread of the small pieced autogenous skin grafts that are covered with homogenous skin graft over post burn wounds in children may give better results than the regular single pieced autogenous skin graft | 2 years |