The Effect of Exercise on Quality of Life, Sleep Quality and Anxiety in Patients With Prediabetes (EFEXQULS)

Study Overview
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Brief Summary
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The aim of this study is to determine the effect of exercise on quality of life, sleep quality and anxiety in patients with prediabetes.

Detailed Description
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Randomized controlled studies are needed to examine the effects of exercise on sleep quality, quality of life, anxiety and depression in patients with prediabetes. The aim of this study is to determine the effect of exercise on quality of life, sleep quality and anxiety in patients with prediabetes.

Official Title
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The Effect of Exercise on Quality of Life, Sleep Quality and Anxiety in Patients With Prediabetes (EFEXQULS)

Conditions
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PreDiabetes, Physical Inactivity, Quality of Life, Sleep, Anxiety, Depression

Intervention / Treatment
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* Behavioral: Exercise


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 18-59 years old Living a sedentary life (physical activity below 300 kcal/day will be evaluated with the Minnesota Leisure Physical Activity Questionnaire) Those who have sufficient motivation to participate in the exercise program (will be evaluated by a one-on-one interview by the researchers) Those diagnosed with prediabetes by oral glucose tolerance test and/or HbA1c measurement will be included. Being eligible to participate in an exercise program after a cardiac examination (resting ECG and questioning of cardiac symptoms, advanced tests such as exercise ECG test if necessary) performed by the physician Exclusion Criteria: Serious medical condition (for example, advanced malignancy or major neurological, psychiatric or endocrine disease, respiratory failure, etc.) that would prevent the person from participating in exercise training. Having cardiovascular disease Being diabetic Receiving hormone replacement therapy Life expectancy less than 1 year HIV positivity Substance use Functional dependency Cognitive weakness Those who have other diseases that will affect the results of the study (respiratory diseases, muscle diseases, etc.) Those who use drugs or supplements that will affect the results of the study

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 59 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Exercise<br>Patients will be given an aerobic exercise program for 1 hour, 3 days a week for 12 weeks. | Behavioral: Exercise<br>* Patients will be given an aerobic exercise program for 1 hour, 3 days a week for 12 weeks<br>|
| No Intervention: Control<br>No intervention will be applied to the patients | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Score of Quality of Life | Quality of Life evaluated with Health-Related Short Form-36 Survey(Min-Max:0-100). High score idicates high quality of life. | 1 week | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Sleep Quality | Sleep Quality evaluated with Pitssburgh Sleep Quality Index (PSQI) (Min-max: 0-100). High score indicates worse sleep quality. | 1 week | 
| Anxiety | Anxiety evaluated with Hospital Anxiety Depression Scale (HADS) (Min-max:0-21). high score indicates high anxiety. | 1 week | 
| Depression | Depression evaluated with Hospital Anxiety Depression Scale (HADS). (Min-max:0-21). high score indicates high depression. | 1 week | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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PreDiabetes, Physical Inactivity, Quality of Life, Sleep, Anxiety, Depression