A Perianal Abscess Cavity Packing vs no Packing.

Study Overview
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Brief Summary
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This prospective randomized trial will be conducted in all patients undergoing packing or no packing for perianal abscess cavity after incision and drainage, for 6 months after approval from IRB in Surgical unit III, Civil Hospital Karachi. Patient will be selected simple random sampling technique based on inclusion criteria. Patient will be assessed for post-operative pain, healing of cavity and recurrence of abscess. At first time of debridement pus or tissue will be sent for culture and sensitivity, meanwhile broad-spectrum antibiotic will be started. Questionnaire will be filled by PI for post-operative pain, recurrence of abscess, quality of life, wound healing, post operative fistula in ano and chronic post surgical pain either due to packing or no packing.

Detailed Description
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This is an experimental randomized control trial will start 6 months after approval from Institution Review Board. All patients with perianal abscess after incision and drainage cavity will be either packed or not after informed consent. Pack will be changed daily as regular dressing till healing occurs. Packing reduces bleeding and heals cavity by effect of dressing solution in which gauze is soaked. Other group with dressing will be changed daily and will be assessed for healing week. There is no pain in simple dressing applied over cavity. Patient will receive broad spectrum antibiotics according to pus or tissue culture. During this period, laboratory investigation CBC, CRP will be sent to check the response. Sits bath will be advised to both groups. Post-operative pain, cavity healing will be assessed by faculty.

Official Title
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A Perianal Abscess Cavity Packing Versus no Packing; a Randomized Control Trial.

Conditions
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Perianal Abscess, Ischiorectal Abscess

Intervention / Treatment
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* Procedure: No packing of perianal abscess cavity


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age greater than 18 years Age less than 70 years Perianal abscess Exclusion Criteria: Suspected inflammatory bowel disease Fournier's gangrene Horseshoe/bilateral abscess

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Experimental Randomized Control Trial
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Perianal abscess cavity packing<br> | Procedure: No packing of perianal abscess cavity<br>* introducing new method to no packing of abscess cavity.<br>|
| Experimental: Perianal abscess cavity no packing<br> | Procedure: No packing of perianal abscess cavity<br>* introducing new method to no packing of abscess cavity.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Post-operative pain | Pain will be assessed via visual analogue scale from 1-10 while changing of dressing. | 14 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Decreases hospital visit | Hospital visits will be decreased when dressing only dressing to be done, not wound packing. | 3 weeks |