linjc16/ctgov huggingface dataset:
A Trial Evaluating the Clinical Applicability, Correlation, and Modeling of Cardiac CT Using 64 Detector Row VCT

Study Overview
=================
Brief Summary
-----------------
To compare computed tomography (CT) images (pictures) of the coronary arteries using the General Electric (GE) LightSpeed VCT scanner with x-ray coronary angiography in patients referred for an x-ray coronary angiography.

Official Title
-----------------
An Open-label, Non-randomized, Multi-center Trial Evaluating the Clinical Applicability, Correlation, and Modeling of Cardiac CT Using 64 Detector Row VCT

Conditions
-----------------
Coronary Artery Disease

Intervention / Treatment
-----------------
* Device: 64 Channel VCT


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients scheduled for elective diagnostic catheterization OR Elective diagnostic catheterization has been performed within the past 2 weeks but no less than 24 hours prior to the coronary CTA procedure with no intervention performed or change of the patient clinical status. Age ≥18 years but ≤75 years. Exclusion Criteria: Prior coronary stent implantation Prior coronary artery bypass grafting or other heart surgery Prior pacemaker or internal defibrillator lead implantation Prior artificial heart valve Biochemical renal insufficiency (CrSerum > 1.6) or on dialysis Resting HR > 100 at the time of enrollment Contraindication to β-blockade or calcium channel blocker NYHA-IV High-grade atrioventricular (AV) block Systolic blood pressure <90 mm Hg Severe asthma or active bronchospasm and/or chronic obstructive pulmonary disease Atrial fibrillation Inability to provide informed consent Evidence of ongoing or active clinical instability Acute chest pain (sudden onset) Acute myocardial infarction Cardiac shock Acute pulmonary edema

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 64 Channel VCT<br>All subjects underwent Coronary Computed Tomographic Angiography (CCTA) after receiving an intravenous (IV) administration of Visipaque (320 mgI/mL), to be followed by catheter coronary angiography (CATH). | Device: 64 Channel VCT<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
Footwear Among Medical Doctors

Study Overview
=================
Brief Summary
-----------------
The footwear fashion among medical doctors has been static for decades with a high preference for clogs. However, other types of shoes have been introduced, including sneakers, sandals etc. In some subspecialties with a need-for-speed, high-agility footwear may be prioritized, while other subspecialist may benefit from easy-to-clean shoes. Even comfortability may influence the choice of footwear. We intend to investigate measures of footwear fashion among medical doctors working at Aarhus University Hospital, Denmark. Participants will be blinded.

Official Title
-----------------
Footwear Among Medical Doctors: An Observational Study of Fashion in Footwear Between Subspecialties

Conditions
-----------------
Shoes

Intervention / Treatment
-----------------
* Behavioral: Footwear


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Medical Doctor working at Aarhus University Hospital, Denmark Wear shoes at work Presence at the randomly selected meetings for medical doctors, where trial personal will perform the footwear assessment. Exclusion Criteria: Medical student Nurse or other health care profession Unidentifiable gender and/or educational level
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Medical Doctors at Aarhus University Hospital, Denmark<br>Medical Doctors from different subspecialties at Aarhus University Hospital, Denmark. Blinded for the purpose of the trial, their footwear will be evaluated by trial responsible personal. | Behavioral: Footwear<br>* Assessment of footwear<br>* Other names: Shoes;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Footwear preference by subspecialty | Differences in footwear between medical subspecialties | Assessed in the data collection period - Spring 2021 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Footwear preference by seniority | Differences in footwear of medical doctors by seniority | Assessed in the data collection period - Spring 2021 | 
| Footwear preference by sex | Differences in footwear between male and female doctors | Assessed in the data collection period - Spring 2021 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Footwear, Fashion, Medical doctors, Clogs
Funguria in Hospitalized Patients

Study Overview
=================
Brief Summary
-----------------
The purpose of the study is to test the hypothesis that a subpopulation of patients with candiduria are at significant risk for disseminated disease and would benefit from treatment, while others are at low risk from complications and therefore require no antifungal therapy.

Detailed Description
-----------------
This protocol will attempt to generate a detailed clinical profile of patients with funguria and identify subgroups of patients with funguria at high risk for candiduria and determine the relative risks for obtaining candiduria. In addition, it will look at identifying subgroups of patients with funguria at high risk for candidemia and identifying subgroups of patients with funguria at high risk for death. Finally, it will attempt to determine if funguria independently predicts fungemia or death. Data will be complemented by surveillance of a comparable population without funguria.

Official Title
-----------------
The Significance of Funguria In Hospitalized Patients

Conditions
-----------------
Candidiasis

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Subjects with fungi isolated from the urine of any colony count. Patients seen at either Harbor-UCLA Medical Center or Cedars Sinai Medical Center. Exclusion Criteria: 1. Persons with a previously positive urine fungal culture during the current hospital admission.

Ages Eligible for Study
-----------------
Maximum Age: 99 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Candidiasis, Funguria
Office-Based Asthma Screening Intervention

Study Overview
=================
Brief Summary
-----------------
In prior work, we found that even children who have been seen by their physicians within the prior six months were frequently misclassified as having mild rather than persistent asthma. This study evaluations whether systematic office-based screening assists primary care physicians in identifying children with significant asthma and improves preventive care for asthma. We hypothesize that standardized screening in the office setting will improve the physician's ability to (a) identify children with significant asthma and (b) prescribe appropriate preventive medications.

Official Title
-----------------
Office-Based Asthma Screening Intervention

Conditions
-----------------
Asthma

Intervention / Treatment
-----------------
* Behavioral: Provider Prompt


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Children ages 2-12 Children arriving for an office visit in two Rochester, NY pediatric clinics Children with a prior diagnosis of asthma AND an exacerbation of symptoms within the previous 2 years Exclusion Criteria: Children arriving at the office visit with an adult that is not their parent or guardian Children arriving at the office visit with a parent or guardian that does not speak English Children with other medical conditions making the assessment of asthma severity difficult (cystic fibrosis, heart conditions, etc.)

Ages Eligible for Study
-----------------
Minimum Age: 2 Years
Maximum Age: 12 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: Provider Prompt|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Preventive Medication Actions (PMA) taken by the provider at the time of the child's visit. A PMA is defined as a new medication prescription or change in medication dose. |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Alternate actions taken by the provider such as: discussion of environmental controls, medication refills, etc. |  |  |
Oscillation Mechanics of the Respiratory System Asbestos Exposed: Early Diagnosis

Study Overview
=================
Brief Summary
-----------------
Inhalation of dust containing asbestos results in a process of interstitial pulmonary fibrosis called asbestosis. The Forced Oscillation Technique (FOT) evaluates the respiratory mechanics describing resistive, elastic and inertial properties. We believe that this technique may contribute to the early diagnosis of asbestosis.

Detailed Description
-----------------
The aims of this study were (1) to use the FOT to analyze how respiratory mechanics is affected in patients with asbestos exposed, (2) to identify the best FOT parameters for the diagnosis of respiratory changes in these patients (3) Assess whether the presence of obstructive changes is associated with the smoking habit.The control group (CG) included 24 subjects with normal spirometric data and without a history of smoking or pulmonary disease formed by workers and students UERJ and FioCruz. Volunteers with asbestos exposure were from the Department of CESTEH/ FioCruz, totaling 24 exposed and 7 with diagnoses of asbestosis. The diagnosis of asbestosis was established based on a history of substantial exposure to asbestos dusts and compatible radiological features, together with exclusion of other competing diagnoses. The tests included a standardized questionnaire on respiratory symptoms, clinical evaluation; Plain radiography of the chest; FOT, plethysmography and spirometry, in that order.

Official Title
-----------------
OSCILLATION MECHANICS OF THE RESPIRATORY SYSTEM ASBESTOS EXPOSED : Early Diagnosis

Conditions
-----------------
Asbestosis

Intervention / Treatment
-----------------
* Other: evaluated lung function


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: diagnosis of asbestosis Exclusion Criteria: other diseases
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: evaluated lung function|lung function tests|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| changes in pulmonary mechanicals |  | 1 year | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
forced oscillation tecnique, lung function, asbestosis
Safety, Tolerability and Pharmacokinetics of Multiple Doses of VAK694 in Atopic Subjects With Seasonal Rhinitis

Study Overview
=================
Brief Summary
-----------------
This study will assess the safety and tolerability of multiple doses of VAK694 as well as change in symptoms and biomarkers in patients with seasonal allergic rhinitis

Official Title
-----------------
A Randomized, Double-blind, Placebo and Calibrator Controlled Study to Assess the Safety, Tolerability and Pharmacokinetics of Multiple Intravenous Doses of VAK694 in Subjects With Seasonal Rhinitis During Natural Exposure to Allergen

Conditions
-----------------
Allergic Rhinitis

Intervention / Treatment
-----------------
* Biological: Placebo
* Biological: VAK694
* Drug: Fluticasone


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Male and female subjects between ages of 18 to 60 in good health History of atopy for at least 2 years and positive skin prick test to ragweed allergen Exclusion criteria: History of asthma treated with corticosteroids Smokers with a smoking history of > 10 pack/years or smoking in the past year History of chronic obstructive pulmonary disease Other protocol-defined inclusion/exclusion criteria may apply

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 60 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Placebo Comparator: Placebo to VAK694<br> | Biological: Placebo<br> <br> |
| Experimental: VAK694<br> | Biological: VAK694<br> <br> |
| Active Comparator: Fluticasone propionate<br> | Drug: Fluticasone<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To assess the safety and tolerability of prolonged administration of multiple intravenous doses of VAK694 as well as the preliminary efficacy of multiple intravenous doses of VAK694 in atopic subjects |  | 12 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To evaluate pharmacokinetics of multiple intravenous doses of VAK694 in atopic subjects |  | 12 weeks | 
| Change in serum levels of total and antigen specific IgE and total and antigen specific IgG |  | 12 weeks | 
| Immunogenicity of multiple intravenous doses of VAK694 |  | 12 weeks | 
| Changes in rhinitis visual-analogue score and the use of symptom relief during both the peak and entire allergy season. |  | 12 weeks | 
| Changes in biomarkers of immunomodulation |  | 12 weeks | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Allergic rhinitis,, atopic patients,, seasonal allergy,, ragweed allergy
The Effectiveness Of Auricular Acupressure On Body Weight Parameters On Patients With Schizophrenia

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to examine whether auricular acupressure is effective in reducing body weight, waist circumference, or lipid profile.

Official Title
-----------------
The Effectiveness Of Auricular Acupressure On Body Weight Parameters On Patients With Schizophrenia

Conditions
-----------------
Schizophrenia, Obesity

Intervention / Treatment
-----------------
* Procedure: auricular acupressure


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: ICD:295,living in chronic ward for more than 2 month Body Mass Index (BMI) >or=24 Age between 20 to 60 Psychotic status stable and can communicate Exclusion Criteria: Unstable psychotic status Participants who have endocrine disease Participants who have cardiac disease Participants who have immunological disease Participants who have liver or renal function impairment Pregnant woman or in milking stage Cerebrovascular accident (CVA) stroke and disability Participant who attends weight control programs in recent 3 months Any conditions that clinical doctors refuse to let join in this study

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 60 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: auricular acupressure|Investigator will put a tape with a 0.5mmx0.5mm seed on the specific positions on the ear of participants of intervention group, and participants will be asked to press these specific positions 3 times a day.|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Using Body weight scale (kilogram) and checking body weight for all participants | all participants are going to be measured body weight per week for 2 months. | 2 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| waist circumference | All participants are going to be measured waist circumference per week for 2 months. | 2 months | 
| Fat percentage by using bio-Impedance Analysis(Tanita-519 machine) | All participants will be measured fat percentage by BIA(Tanita-519) per 2 months. | 2 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
auricular acupressure, obesity, schizophrenia, body weight
The Long Term Outcomes of Micronutrient Antioxidant Supplementation in Patients With Chronic Pancreatitis

Study Overview
=================
Brief Summary
-----------------
This is a anonymised case note study looking at the long term outcomes of patients with Chronic Pancreatitis on micro nutrient antioxidant treatment.

Detailed Description
-----------------
Chronic pancreatitis is the medical term for chronic inflammation of the pancreas. This illness is associated with long-term abdominal pain. In the 1980s it was proposed that chronic pancreatitis was due to a deficiency of protective antioxidants in the pancreas and on this basis antioxidant therapy was introduced. This therapy was highly controversial until a large randomised trial of antioxidant therapy in chronic pancreatitis, undertaken in Manchester showed that 6 months intervention with antioxidant therapy was not associated with any change in pain score or improvement in quality of life. Antioxidant therapy is no longer used in modern day pancreatic practice. However, as with any study, the randomised trial raised some specific questions. First, does treatment for more than 6 months provide benefit? Second, are there disease sub-types of chronic pancreatitis where antioxidant therapy may benefit? Given the lack of contemporary use of antioxidant therapy, this question cannot be answered in a prospective study. However, the case records of the Manchester Royal Infirmary contain information on antioxidant treatment in patients who received this therapy over a prolonged period. Thus the aim of the present study is to review the case notes of patients given a discharge code from the Manchester Royal Infirmary of chronic pancreatitis during the period 1st January 1990 to 1st January 1998 in order to assess whether there is a record of improvement in outcome. Only the case notes will be reviewed and patients will be given an opportunity to opt out. The study accepts the limitations of assessing pain from clinical notes but also notes that more objective findings such as development of diabetes mellitus (a long term complication of chronic pancreatitis) can be assessed from the notes.

Official Title
-----------------
The Long Term Outcomes of Micronutrient Antioxidant Supplementation in Patients With Chronic Pancreatitis

Conditions
-----------------
Chronic Pancreatitis

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with Chronic Pancreatitis treated with Long term anti-oxidants Exclusion Criteria: Cancer, On trials

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 99 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain Relief |  | 10 years | 
| Insulin Dependence |  | 10 years |