Effect of Re-education on Rebleeding Rate After Endoscopic Treatment in Liver Cirrhosis

Study Overview
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Brief Summary
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A prospective, randomized controlled study on whether re-education after discharge can reduce the rebleeding rate after endoscopic treatment of esophageal and gastric varices in patients with liver cirrhosis

Detailed Description
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After receiving esophageal variceal ligation and （or） gastric fundus variceal sclerotherapy, patients with outside hospitalthe rate of bleeding due to liver cirrhosis shall be re-educated outside the hospital, including diet, drugs, anticoagulation of portal vein thrombosis,regular endoscopic treatment, reexamination , nutrition, etc. The patients were divided into the first treatment group and the more thanonce treatment group according to whether they had received endoscopic treatment in the past

Official Title
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Effect of Re-education on Rebleeding Rate After Endoscopic Treatment of Esophageal and/or Gastric Varices in Patients With Liver Cirrhosis

Conditions
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Bleeding, Liver Cirrhosis, Esophageal Varices Bleeding, Gastric Variceal Bleeding

Intervention / Treatment
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* Behavioral: re-education


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Esophageal and / or gastric varices ； liver cirrhosis ； patients receiving endoscopic treatment (esophagogastric variceal sclerosis and/or ligation) ； All subjects or their guardians must sign the subject consent form before entering the test Exclusion Criteria: Patients with mental illness, severe hearing loss and unable to take care of themselves ; ASA score ≥ grade IV at discharge ; Hepatic encephalopathy ≥ stage II; Patients with liver cancer; Pregnant and lactating women; Patients who cannot sign informed consent

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: case group will receive re-education after leave hospital<br>The participants were randomly divided into re-education group and non re-education group according to the random number table. The re-education group will receive regular re-education not noly when they leave hospital but also after leave hospital in our preset time by telephone or wechat. The content of re-education includes diet form and diet structure,medication compliance and regularity, and recheck compliance, moderate exercise and so on | Behavioral: re-education<br>* Contact patients by phone or wechat and guide them<br>|
| No Intervention: control case group will receive no re-education after leave hospital<br>The participants were randomly divided into re-education group and non re-education group according to the random number table. without re-education group will receive regular re-education when they leave hospital.The content of re-education includes diet form and diet structure,medication compliance and regularity, and recheck compliance, moderate exercise and so on | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| rebleeding | rebleeding from any channel can be followed up through medical institutions or telephone | 2 yeas |