ATtention Test and Executive Functions After STroke to Predict Depression.

Study Overview
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Brief Summary
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The purpose of this study is to determine whether cognitive function evaluation (sustained attention, executive functions, working memory) during acute post-stroke is predictive of a 3 months post-stroke depression.

Detailed Description
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Baseline visit: after neurologic stability, 14 days or less after stroke and before discharge. First assessment : Neurologic data: morphologic data (MRI of the brain), stroke severity (NIHSScore), aphasia assessment (Boston Diagnostic Aphasia Examination) if NIHS verbal score ≥1, hemineglect assessment (Bells test). Personal data assessment : i. Socio demographic : age, gender, marital status, employment, level of education ii. Medical history: medical treatments, psychiatric and non psychiatric history. c. Psychiatric assessment i. Mini International Neuropsychiatric Interview - depression ii. Beck Depression Inventory iii. Clinical Global Impression iv. Standardized Assessment of Personality - Abbreviated Scale (SAPAS) v. Fageström-C vi. Alcohol Use Disorders Identification Test (AUDIT-C) d. Cognitive assessment: i. Verbal memory : Dubois's five words ii. Clock drawing test iii. D2test (computerized) iv. Verbal fluency (Cardebat) v. Working memory (digit span WAIS 3) vi. Brixton (computerized) Assessment 3 months after the first assessment. Phone call and psychiatric assessment: MINI depression, Beck Depression Inventory. Barthel index and Quality of Life assessment.

Official Title
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Predictivity of Attention Test and Executive Functions After Stroke to Predict Depression 3 Months After Stroke.

Conditions
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Post-stroke Depression

Intervention / Treatment
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* Other: Thymic history
* Other: Evaluation of the psychiatric disorders
* Other: Cognitive evaluation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 18 or more Ischemic or hemorragic stroke, diagnosed with radiology : cerebral CT or MRI, 14 days or less after stroke Signed Consent Social insurance regime affiliation Exclusion Criteria: Death No possibility of follow-up No French-speaker : insufficient command of French Deprivation of liberty : judicial or administrative decision D2 test assessment impossibility Aphasia with major disorder of the understanding (Boston <8) Antidepressant treatment during stroke Depression during stroke protected people

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Screening
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Patients<br>Assessments are made by a psychiatrist | Other: Thymic history<br>* This interview concerns mainly the nature of the previous psychiatric and psychological care<br>Other: Evaluation of the psychiatric disorders<br>* Mini International Neuropsychiatric Interview for the positive diagnosis of depression - under the MINI score of depression.<br>Other: Cognitive evaluation<br>* They will be held consecutively to the patient's bedside interview on the same day. Some tests will be computerized, others will be in paper form.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Post stroke depression | Whether or not a post-stroke depression occurs. occurrence of post-stroke depression assessed with Mini International Neuropsychiatric Interview (MINI), subscale depression . | 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Post-stroke depression population characterization | Age, gender, marital status, occupation, level of education, laterality of stroke,and medical and psychiatric history will be collected during the inclusion interview and cognitive tests | 1 day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Depression