linjc16/ctgov huggingface dataset:
Establish and Apply the Evaluation System of Ultrasonic Integrated Technology for Prevention and Treatment of Acute Kidney Injury

Study Overview
=================
Brief Summary
-----------------
Establish an integrated evaluation system of ultrasound technology for the prognosis of acute kidney injury, and in order to achieve non-invasive, reliable early diagnosis gold standard. Set up collabration with the expert in National Cheng Kung University Medical Center of Taiwan who did a lot of excellent work in basic research of prevention the progression of acut kidney injury. Study the experience about prevention progression of kidney disease in clinical and basic field. Establish cooperation with the professional in Hong Kong University of Science and Technology. To set up the system of natural products research and assess the Astragalus medicinal value.

Official Title
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Establish and Apply the Evaluation System of Ultrasonic Integrated Technology for Prevention and Treatment of Acute Kidney Injury

Conditions
-----------------
Acute Kidney Injury

Intervention / Treatment
-----------------
* Other: kidney ultrasound


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Subjects must satisfy the following criteria to be enrolled in the study: Clinical diagnosis of acute or chronic kidney injury Male or female, aged 18-80 years old signed informed consent Patients can breathe in, breathe out and hold their breathe with ease, communication without difficulty. Exclusion Criteria: Potential subjects who meet any of the following criteria will be excluded from participating in the study: Refuse to sign informed consent allergy to micro bubble hexafluoride drug Patients with cardiopulmonary insufficiency, pleural effusion, pulmonary infections Patients with asthma, chronic bronchitis Patients with pregnancy Patients can't cooperate or have a difficulty in breathing in, breathing out or holding their breathe Patients beening diagnosed with End-stage kidney disease.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Confirmed acute kidney injury<br>Confirmed acute kidney injury | Other: kidney ultrasound<br>* kidney ultrasound<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| compare the results of kidney ultrasound with biomarkers of acute kidney injury |  | up to 24 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
acute kidney injury, ultrasound technology
Effects of Weight Loss From Bariatric Surgery on Intraocular Pressure (IOP)

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to determine if there is an effect on the eye pressure from extreme weight loss by bariatric procedures. The hypothesis is that excess fat in the orbit of the eye compresses on the outflow system, which causes an elevated eye pressure. This can have many consequences, including the risk for glaucoma. We hope to establish if there is an effect between eye pressure and weight.

Official Title
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The Effects of Weight Loss From Bariatric Surgery on Intraocular Pressure

Conditions
-----------------
Intraocular Pressure

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age ≥ 18 Written informed consent obtained BMI > 40 kg/m2 without associated comorbidities or > 35 kg/m2 with associated comorbidities. In the normal indication for routine bariatric surgery, comorbidities include hypertension, type II diabetes, venous stasis, sleep apnea, polycystic ovary syndrome, pseudotumor cerebri, nonalcoholic steatohepatitis, gastroesophageal reflux disease, coronary artery disease, degenerative joint disease, cancer, and hypercholesterolemia. Exclusion Criteria: Current use of systemic steroids Any systemic medication which is unstable and can affect IOP History or evidence of glaucoma Any ocular trauma or ocular surgery Outside normal range of corneal thickness (500-600 microns) Unable to follow-up for 3 years Participating in any investigational device or medication study within 30 days of baseline

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Study group-Bariatric procedure performed<br> | |
| Control group: No bariatric procedures<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Intraocular pressure |  | Data will be recorded the same day when a patient comes to the clinic. |
HERO Study: Helping Evaluate Reduction in Obesity

Study Overview
=================
Brief Summary
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A prospective, international, multi-center study of clinical outcomes and estimated healthcare resource expenditures associated with the treatment of obesity using the LAP-BAND AP® Adjustable Gastric Banding System.

Conditions
-----------------
Obesity

Intervention / Treatment
-----------------
* Device: LAP-BAND AP® Adjustable Gastric Banding System


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patient and investigator have made a decision, independent of the study, to proceed with LAP-BAND AP® implantation. Male or female aged ≥ 18 years. BMI ≥ 40 or a BMI ≥ 35 with one or more severe co-morbid conditions, or those who are 45.5 Kg / 100 lbs or more over their estimated ideal weight. Exclusion Criteria: Prior bariatric surgery. Type I diabetes patients. Participating in another ongoing clinical study with concomitant diagnostic or therapeutic intervention that would reasonably be expected to alter patterns of care, use of medications or the outcomes under study.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| LapBand<br>Patients who have already consented to receive the LAP-BAND AP® Adjustable Gastric Banding System | Device: LAP-BAND AP® Adjustable Gastric Banding System<br>* The LAP-BAND AP® is a device surgically implanted via a laparoscopic procedure. It is designed to induce weight loss in severely obese patients by limiting food consumption.<br>* Other names: LAP-BAND AP®;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| %TBWL | Percent of total body weight change. | 5 years |
Survey of Non-resuscitation Fluids in Septic Shock

Study Overview
=================
Brief Summary
-----------------
The objective of this study is to survey the type and the amount of non-resuscitation fluids that patients with septic shock receives during their first 5 days of ICU admission.

Detailed Description
-----------------
Background: Several studies indicate that a large part of the fluid intake in intensive care patients consists of fluids that are given for indications other than volume expansion. However, the type of non-resuscitation fluids that hemodynamically unstable ICU patients receive has not been well characterized. Methods: A multicenter observational cohort study. Baseline data including, sex, age, physiological data at admission, source of sepsis, illness severity, and ICU and hospital mortality will be collected. Fluids administered during the first five days of ICU admission will be registered. Fluids used as vehicle to administer drugs will be regarded as non-resuscitation fluids and will be characterized in detail. All glucose solutions will be regarded as non-resuscitation fluids. Crystalloids delivered at a rate of < 5 ml/kg/h will be considered as non-resuscitation fluids. Parenteral nutrition will be regarded as non-resuscitation fluids. Crystalloids delivered at a rate of ≥ 5 ml/kg/h will be considered to be resuscitation fluids. Blood products and colloids will be regarded as resuscitation fluids.

Official Title
-----------------
Survey of Non-resuscitation Fluids in Septic Shock

Conditions
-----------------
Septic Shock

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Septic shock per SEPSIS-3 criteria within 24 hrs of ICU admission Informed consent from patient or next of kin if required by local ethical review Board Exclusion Criteria: • Lack of informed consent (see above)

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Type, indication and volume of fluids given to septic shock patients for other reasons than circulatory support. | Type of fluid is defined as either 0.9% normal saline, glucose, Ringers acetate/lactate, enteral nutrition, parenteral nutrition or sterile water. Indication is defined as vehicle, nutrition, maintenance or other. Volume will be reported in ml. | First five days in ICU | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Fluid therapy, Non-resuscitation fluids, Septic shock
The Critical Threshold of Pulse Oximetry Plethysmographic Waveform Parameters in High Quality CPR

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to analyze the relationship of the area under the curve (AUC) and/or the amplitude (Amp) of pulse oximetry plethysmographic waveform (POP) with partial pressure of end-tidal carbon dioxide (PETCO2) which could be used to reflect its quality in cardiopulmonary resuscitation (CPR), and then to determine the critical threshold of POP parameters in high quality CPR.

Conditions
-----------------
Cardiopulmonary Resuscitation

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Cardiac arrested The time from cardiac arrest to receiving basic life support is less than 10 minutes Get advanced life support (endotracheal intubation and PETCO2 monitoring) Exclusion Criteria: Defuse CPR chronic obstructive pulmonary disease (COPD) with type II respiratory failure Terminal malignant tumors or terminal stage of other diseases Rib fracture Cardiac arrest caused by hemorrhagic shock pulmonary embolism and cardiac tamponade Sever anemia(HGB<7g/dl) Untreated tension pneumothorax Tinea unguium, dyeing Fingernails and other factors affect the monitor of Pulse Oximetry Plethysmographic Waveform such vasculitis and Raynaud's phenomenon

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the cut-off value of POP parameters in High Quality CPR | Describe the the cut-off value of POP parameters in High Quality CPR. Receiver operating curve analysis was performed to evaluate the accuracy in predicting return of spontaneous circulation (ROSC). | one year | 
| Compare different predictors | Area under curve (AUC) between potential predictors was compared by using a nonparametric test, and the optimal cutoff point was determined by estimating the Youden's index. | one year | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
cardiopulmonary resuscitation, pulse oximetry plethysmographic waveform, quality monitor, partial pressure of end-tidal carbon dioxide
Mental Health Status and Related Factors Among Physical Medicine & Rehabilitation Physicians in the Covid-19 Pandemic

Study Overview
=================
Brief Summary
-----------------
In December 2019, a highly infectious disease caused by a novel coronavirus (SARS-CoV-2) emerged in Wuhan, China. On March 11th 2020, the World Health Organization (WHO) declared COVID-19 a pandemic. Facing this critical situation, health care workers on the front line are at risk of developing psychological distress and other mental health symptoms. Physical medicine and rehabilitation (PM&R) physicians works both in specialty outpateint/inpatient clinic and pandemic outpatient/inpatient clinics during the outbreak. Accordingly, PM&R physicians are expected to be mentally affected by COVID-19 pandemic. In this study we aimed to evaluate mental health status of PM&R physicians and related factors during COVID-19 pandemic. This study is a cross-sectional survey which is conducted on an online platform. Demographic data, working conditions of PM&R physicians and factors that may be related to mental health status is questioned in the survey. The Depression, Anxiety and Stress Scale - 21 (DASS-21) is used to measure the emotional states of depression, anxiety and stress.The Insomnia Severity Index (ISI) is used to assess the severity of both nighttime and daytime components of insomnia.

Official Title
-----------------
Evaluation of Mental Health Status and Related Factors Among Physical Medicine & Rehabilitation Physicians During the Covid-19 Pandemic

Conditions
-----------------
Anxiety, Depression, Insomnia, Covid19, Coronavirus

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Being a physical medicine and rehabilitation physician Worked during COVID-19 pandemic in specialty outpatient/inpatient clinic or pandemic outpatient/inpatient clinic. Exclusion Criteria: Being a specialist in a branch other than physical medicine and rehabilitation

Ages Eligible for Study
-----------------
Minimum Age: 24 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Depression, Anxiety and Stress Scales 21 Score | The Depression, Anxiety and Stress Scale - 21 Items (DASS-21) is a set of three self-report scales designed to measure the emotional states of depression, anxiety and stress. | 5 months | 
| Insomnia severity index score | The Insomnia Severity Index (ISI) is a brief instrument that was designed to assess the severity of both nighttime and daytime components of insomnia. | 5 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
depression, anxiety, insomnia, Covid-19, coronavirus
Focus Group in Collecting Feedbacks From Indoor Tanning Bed Users for Social Media-Delivered Intervention Development

Study Overview
=================
Brief Summary
-----------------
This research trial collects feedbacks from indoor tanning bed users via focus group for the development of social media-delivered intervention. Conducting a focus group with people using indoor tanning bed and having access to Facebook may help doctors to better understand people's perspective and thoughts about the various Facebook messages.

Detailed Description
-----------------
PRIMARY OBJECTIVES: I. To elicit feedback from young adult women who use indoor tanning beds on preliminary intervention content. OUTLINE: Participants attend a focus group session and review printed copies of planned posts for the to-be-developed Facebook intervention over 90 minutes to 2 hours.

Official Title
-----------------
Developing a Social Media-Delivered Intervention

Conditions
-----------------
Health Status Unknown

Intervention / Treatment
-----------------
* Other: Questionnaire Administration
* Other: Survey Administration


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Use of an indoor tanning bed at least 10 times in the past 12 months At least daily use of Facebook

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 25 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Observational (focus group)<br>Participants attend a focus group session and review printed copies of planned posts for the to-be-developed Facebook intervention over 90 minutes to 2 hours. | Other: Questionnaire Administration<br>* Ancillary studies<br>Other: Survey Administration<br>* Ancillary studies<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Participants feedback | Focus group questions will elicit descriptions of general interest. Participants will also rate various posts on the hand-out sheets included in the script. | Up to 2 years | 
| Participants feedback | Focus group questions will elicit descriptions of posts, and as well as suggestions for improving existing posts or creating new ones. Participants will also rate various posts on the hand-out sheets included in the script. | Up to 2 years | 
| Participants feedback | Focus group questions will elicit descriptions of general interest of topics. Participants will also rate various posts on the hand-out sheets included in the script. | Up to 2 years |
Characterization of Dyslipidemia in Adolescent Obesity

Study Overview
=================
Brief Summary
-----------------
The primary objective of this pilot study is to characterize the profile of lipoprotein, inflammatory, and metabolic markers of cardiovascular disease in obese adolescents as compared to normal-weight age-matched controls.

Official Title
-----------------
Characterization of Dyslipidemia in Adolescent Obesity

Conditions
-----------------
Obesity

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age 13-19 BMI ≥25 (obese) or <25 (normal weight) Exclusion Criteria: Prior diagnosis of any eating disorder (e.g. anorexia or bulimia) Prior diagnosis of any congenital lipid disorder (e.g. familial hypercholesterolemia) Current use (or within past 6 months) of any lipid altering medications

Ages Eligible for Study
-----------------
Minimum Age: 13 Years
Maximum Age: 19 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Comparison of biomarker profiles | To characterize and compare lipoprotein, inflammation and metabolic markers in obese and normal weight adolescents. | Baseline |
Myocardial Infarction and Past Oral Contraceptive Use

Study Overview
=================
Brief Summary
-----------------
To evaluate whether the long-term use of oral contraceptives, after discontinuation, was associated with an increased incidence of first nonfatal myocardial infarction among women above the age of 50.

Detailed Description
-----------------
BACKGROUND: In the mid 1980s, it was known that current oral contraceptive use (in the preceding month) increased the risk of myocardial infarction three to four-fold. Evidence seemed to indicate that past use lasting a total of five or more years was associated with a residual two-fold increase in myocardial infarction risk among women 40 to 49 years old. Since the incidence of the disease started to become appreciable beyond age 49, it was of public health importance to reexamine the evidence in a data base which included women aged 50 or older to determine how long the increased risk persisted and whether it varied according to the formulation of the preparation used. An increase in risk that persisted after discontinuation of oral contraceptive use would have major public health implications since millions of women have used or will use oral contraceptives for long periods. DESIGN NARRATIVE: The design was that of a case-control study. Cases were identified by weekly telephone calls to the coronary care units of 78 hospitals in greater Boston, Southern Connecticut, and Westchester County. Nurse-interviewers administered standard interviews to cases convalescing on medical wards after discharge from coronary care units and to controls identified in the same hospitals. Histories of oral contraceptive use, including the timing and duration of use and the name of the preparations, were recorded along with information on other drug use and myocardial infarction risk factors such as cigarette smoking. Data were collected for three years. The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System (PRS) record.

Conditions
-----------------
Cardiovascular Diseases, Coronary Disease, Myocardial Infarction, Heart Diseases, Menopause, Postmenopause

Participation Criteria
=================
Eligibility Criteria
-----------------
No eligibility criteria

Ages Eligible for Study
-----------------
Maximum Age: 100 Years

Sexes Eligible for Study
-----------------
Male

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |