Traumatic Brain Injury and Stroke Long Term Outcome

Study Overview
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Brief Summary
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Investigators will determine the long-lasting effects of post-acute rehabilitation after traumatic brain injury and stroke. Investigators will also evaluate if the beneficial effects of rehabilitation continue after discharge from a rehabilitative program.

Detailed Description
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The long-term effects of rehabilitation will be evaluated on 60 patients with traumatic brain injury (TBI) and 60 patients that suffered a cerebrovascular accident (CVA) that underwent an comprehensive rehabilitative. These patients will be matched with subjects that received limited or no rehabilitation rehabilitative therapy. Thus, the total number of subjects in this study will be 240. Subjects will be contacted at least 1 year after discharge and will be lowed up every two-years thereafter for a total period of 10 years. Procedures will be performed in-person whenever possible. However, it is highly likely that the majority of participants will be contacted via phone interviews. Aim 1: Determine if rehabilitation improves vocational status and living status after TBI and CVA. Aim 2: Determine if rehabilitation improves life quality after TBI and CVA. Aim 3: Determine if rehabilitation improves cognitive function after TBI and CVA. Aim 4: Determine if rehabilitative benefits are sustained. Aim 5: Determine if long-term outcome is dependent on the duration of rehabilitation. Aim 6: Determine if long-term outcome is dependent on the nature of the rehabilitative treatment by comparing the effects of different types of rehabilitation. These will include the following: residential-multidisciplinary, day-treatment (i.e. full time multidisciplinary outpatient), outpatient (part-time), skilled nursing and no post-acute rehabilitation.

Official Title
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Effects of Rehabilitation Following Traumatic Brain Injury and Stroke: A Long Term Outcome Study.

Conditions
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Traumatic Brain Injury, Stroke

Intervention / Treatment
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* Other: Post Acute Rehabiltation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Endured a traumatic brain injury or stroke Subject or caretaker should be Fluent in English Exclusion Criteria: Diagnosis of degenerative neurological disease prior to sustaining stroke or traumatic brain injury b) A history of major psychosis as defined by Diagnostic and Statistical Manual of Mental Disorders (DSM-V) prior to sustaining stroke or traumatic brain injury

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| TBI + Rehabilitation<br>Traumatic Brain Injury patients that received post acute rehabilitation | Other: Post Acute Rehabiltation<br> <br> |
| TBI + No Rehabilitation<br>Traumatic Brain Injury patients that did not receive post acute rehabilitation | |
| CVA + Rehabilitation<br>Stroke patients that received post acute rehabilitation | Other: Post Acute Rehabiltation<br> <br> |
| CVA + No Rehabilitation<br>Stroke patients that did not received post acute rehabilitation | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Effects of rehabilitation on long term occupational Status after injury | Occupational Status Questionnaire | 1 to 10 years | 
| Effects of rehabilitation on long term cognitive function after injury | Brief Test of Adult Cognition by Telephone | 1 to 10 years | 
| Effects of rehabilitation on long term disability function after injury | Supervision Rating Scale and Disability Rating Scale | 1 to 10 years | 
| Effects of rehabilitation on long term quality of life after injury | Quality of Life in Neurological Disorders Measures (NeuroQOL) | 1 to 10 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Effects of rehabilitation on long term health after injury | TBI and Health in Adults Questionnaire | 1 to 10 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Rehabilitation, Long term outcome