Early Incentive and Mobilization During COPD Exacerbation

Study Overview
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Brief Summary
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To study the effects of early exercise training in hospitalized patients for Chronic Obstructive Pulmonary Disease exacerbation (COPD). Interventions are randomized. In one group, early exercise training (aerobic and strength) during hospitalization for COPD exacerbation followed by exercise training at home until 30 days to discharge and in the other the intervention is usual care. In both groups, usual respiratory physiotherapy techniques during hospitalization and adequate physical activity recommendations have been included. The main variable is the increase in moderate or vigorous daily physical activities at 30 days after discharge.

Detailed Description
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Prospective randomized study in hospitalized patients for Chronic Obstructive Pulmonary Disease exacerbation (COPD). In one group, early exercise training (aerobic and strength) during hospitalization for COPD exacerbation followed by exercise training at home until 30 days to discharge and in the other the intervention is usual care. In both group, usual respiratory physiotherapy techniques during hospitalization and adequate physical activity recommendations have been included. The main variable is the increase in moderate or vigorous daily physical activities at 30 days after discharge.

Official Title
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Early Incentive and Mobilization During COPD Exacerbation

Conditions
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Chronic Obstructive Pulmonary Disease

Intervention / Treatment
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* Other: Hospital and home exercise training
* Other: Usual care


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Hospitalized patients for COPD exacerbation Exclusion Criteria: Hospitalization within the previous 14 days, current participation in rehabilitation program, locomotor or neurological condition or disability limiting the ability to perform exercise, lung transplantation or lung volume reduction surgery foreseen within 1 month after discharge.

Ages Eligible for Study
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Minimum Age: 45 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Hospital and home exercise training<br>Usual care plus hospital exercise training (aerobic and strength) followed by exercise training at home until 30 days to discharge. | Other: Hospital and home exercise training<br>* Hospital exercise training (aerobic and strength) followed by exercise training<br>|
| Other: Usual care<br>Usual care in COPD | Other: Usual care<br>* Usual care includes respiratory physiotherapy techniques during hospitalization and adequate physical activity recommendations, but not exercise training<br>* Other names: Usual recommendations;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Daily physical activity | Increase 10% moderate and/or vigorous daily physical activities after discharge | 1 month | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Tolerance to exercise | Six minutes walk test | 1 month | 
| COPD Assessment Test (CAT) | Quality of life | 1 month | 
| Physical activity | International Physical Activity Questionnaire (IPAQ) | 1 month | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Chronic obstructive pulmonary disease