Cohort Follow-up: Progression and Consequences of Chronic Kidney Disease.

Study Overview
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Brief Summary
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This study aims to conduct a prospective collection of clinical and para-clinical data in patients with Chronic Renal Diseases to identify disease progression factors, markers of renal function, and the pathophysiology of Chronic Renal Diseases complications.

Detailed Description
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Chronic Renal Diseases have a growing incidence and prevalence in France, with significant consequences in terms of morbidity and mortality, especially cardiovascular, and Public Health. It is necessary to know better: the mechanisms leading to the progression of the Chronic Renal Diseases markers to quantify renal function and progression of the Chronic Renal Diseases the pathophysiology of Chronic Renal Diseases complications, cardiovascular, nutritional, or mineral metabolism in particular. This study aims to conduct a prospective collection of clinical and para-clinical data in patients with Chronic Renal Diseases to identify disease progression factors, markers of renal function, and the pathophysiology of Chronic Renal Diseases complications.

Official Title
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Cohort Follow-up: Progression and Consequences of Chronic Kidney Disease.

Conditions
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Chronic Renal Diseases, Renal Function Disorder

Intervention / Treatment
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* Procedure: Blood sample
* Procedure: Urine sample


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients with Chronic Renal Disease, stage 2 to 5, non-dialysis patients over the age of 18, followed in the Nephrology Department of the Bordeaux University Hospital agreeing to participate in NephroTest affiliated with social security. Exclusion Criteria: Patients under 18 years Patients with acute or rapidly progressive renal failure Patients with severe comorbidities or comorbidities that are life-threatening in the short term (<1 year) Patients who did not give their written consent to be included in the study Major incapacitated patients and psychiatric patients admitted to hospital

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: Blood sample|A dry tube of 7 ml of blood, two 4 ml EDTA tubes, a 4 ml heparinized tube and an 8.5 ml ACD-A tube will be collected from the patient.|
|Procedure: Urine sample|The urine will be taken from three 15 ml tubes.|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Estimated Glomerular Filtration Rate measurement | by isotope technique | At 1 year after inclusion | 
| Estimated Glomerular Filtration Rate measurement | by isotope technique | At 2 year after inclusion | 
| Measured Glomerular Filtration Rate | by isotope technique | At 1 year after inclusion | 
| Measured Glomerular Filtration Rate | by isotope technique | At 2 years after inclusion |