Hydrolyzed Collagen Combined With Djulis and Green Caviar Improve Skin Condition

Study Overview
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Brief Summary
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Collagen combined with djulis and green caviar improve skin condition

Detailed Description
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Using collagen drinks combined fish collagen with djulis, and green caviar to improve skin condition.

Official Title
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Hydrolyzed Collagen Combined With Djulis and Green Caviar Improve Skin Condition

Conditions
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Skin Condition

Intervention / Treatment
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* Dietary Supplement: placebo group
* Dietary Supplement: collagen drinkss


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Dry skin Rough skin Large pores Dark yellow complexion Sagging skin Exclusion Criteria: Skin disorders Liver diseases Kidney diseases Allergy to cosmetics, drugs, or foods Pregnant and lactating women People who had any cosmetic procedures before 4 weeks of the study Area of facial spot over 3 cm2 Vegan People who took collagen supplements in the past 3 months.

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Placebo Comparator: placebo group<br>subjects drank 50 ml every night for 14, 28 days | Dietary Supplement: placebo group<br>* subjects drank 50 ml every night for 14, 28 days<br>|
| Experimental: collagen drinks<br>subjects drank 50 ml every night for 14, 28 days | Dietary Supplement: collagen drinkss<br>* subjects drank 50 ml every night for 14, 28 days<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| skin moisture | using corneometer CM825 to examine skin moisture (The higher the value, the more water content, C.U., corneometer units ) | subjects drank 50 ml every night for 28 days | 
| skin elasticity | using cutometer dual MPA580 to examine skin elasticity (The closer the R2 value is to 1, the better the elasticity and no unit) | subjects drank 50 ml every night for 28 days | 
| skin gloss | using probe system GL2000 & MPA10 to examine skin gloss (The higher the value, the higher the gloss, no unit) | subjects drank 50 ml every night for 28 days | 
| skin spot | usig VISIA-CR to examine skin spot (The higher the value, the larger the pore area, mm2) | subjects drank 50 ml every night for 28 days | 
| skin wrinkle | using VISIOSCAN-VC20 to examine skin wrinkle (The higher the value, the more wrinkles, surface evaluation of wrinkles, SEW) | subjects drank 50 ml every night for 28 days | 
| skin roughness | using VISIOSCAN-VC98 to examine skin roughness (The higher the value, the higher the roughness, surface evaluation of roughness, SEr) | subjects drank 50 ml every night for 28 days | 
| skin smoothness | using VISIOSCAN-VC98 to examine skin smoothness (The lower the value, the higher the smoothness, surface evaluation of smoothness, SEsm) | subjects drank 50 ml every night for 28 days |