Genital Wart and Sexuality in Adolescence

Study Overview
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Brief Summary
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The adolescence is a landmark in perceiving the sexuality and awareness about the sexual experiences. Genitals warts were shown to be a potential risk to impair the sexual functions in women. Adolescence is a vulnerable period in which the individuals may be prone to the negative effects of the disorders affecting sexual functions such as genital warts. The current study aimed to investigate the impact of genital warts on sexual functions in female adolescents.

Detailed Description
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This current study aimed to elucidate the impact of genital warts on female sexual function in adolescence. The current study also targeted to reveal whether there is any correlation between the genital warts and the female sexual dysfunction, as well as the sexuality related distress. The current study is conducted at Youth Center Outpatient Clinic of Ankara City Hospital which is a high-volume tertiary health care center in Turkey. The study was prospectively designed and data were collected between the 1 August 2020 and 1 February 2021. Totally 90 female adolescents between the age of 17-21 who had regular sexual intercourse with heterosexual partners were included. The Study group composed of 45 adolescents who had genital warts and the Control group included 45 healthy adolescents. Female sexual function Index (FSFI), Arizona Sexual Experiences Scale (ASEX) and Female Sexual Dysfunction Scale (FSDS) scores were compared between the two groups to evaluate the sexual functions. Difference between two independent means (two groups) power analysis demonstrated that this study achieved a power of 0.99, 0.98 , 0.99 with a 5% level of significance for comparison of 45 adolescents with genital warts and 45 healthy adolescents in terms of FSFI, ASEX, and FSDS scores, respectively.

Official Title
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Genital Warts is Related With Sexual Dysfunction and Sexual Distress in Adolescence

Conditions
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Adolescent Development, Genital Wart, Sexual Dysfunction, Sexual Disorder, Physiological

Intervention / Treatment
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* Other: Clinical assessment


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: The Study group included adolescents who was diagnosed as positive for genital warts during the examination. The Control group was composed of healthy adolescents who admitted for contraceptive counselling. Exclusion Criteria: Chronical disease including rheumatological diseases, renal failure, diabetes mellitus, hypertension, dyslipidemia, obesity, thyroid dysfunction, cardiopulmonary diseases, malignancy, cerebrovascular diseases, psychiatric and mental disorders, cerebrovascular diseases, inflammatory bowel diseases. Drug administration which may interfere sexual function. Surgical intervention to genital organs. History of pregnancy, delivery, and/or breastfeeding.

Ages Eligible for Study
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Minimum Age: 17 Years
Maximum Age: 21 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Adolescents with genital warts (Study Group)<br>The Study group included adolescents who was diagnosed as positive for genital warts during the examination. | Other: Clinical assessment<br>* FSFI, ASEX and FSDS scores were compared between the adolescents with (Study group) or without (Control group) genital warts.<br>|
| Healthy adolescents (Control Group)<br>The Control group was composed of healthy adolescents who admitted for only contraceptive counselling. | Other: Clinical assessment<br>* FSFI, ASEX and FSDS scores were compared between the adolescents with (Study group) or without (Control group) genital warts.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Female Sexual Function Index | Questionnaire score with minimum and maximum levels of 2.4 and 36 points,respectively. Higher scores mean a better outcome. | Through study completion, an average of 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Arizona Sexual Experiences Scale | Questionnaire score with minimum and maximum levels of 5 and 30 points,respectively. Higher scores mean a worse outcome. | Through study completion, an average of 6 months | 
| Female Sexual Distress Scale-Revised | Questionnaire score with minimum and maximum levels of 0 and 50 points,respectively. Higher scores mean a worse outcome. | Through study completion, an average of 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Genital wart, Female sexual dysfunction, Late adolescence, Sexuality related distress