Dose-effect of HIIT on Cardiovascular Health of Children

Study Overview
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Brief Summary
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An adequate physical activity level has important effects on cardiovascular health of children. However, the scientific literature suggests that few children meet the physical activity recommendations to obtain these cardiovascular benefits which may have immediate and long term consequences in public health. High intensity interval training (HIIT) has emerged as an effective strategy for improving physical and mental health in children. To note that HIIT can be completed in a shorter period of time and its results in physical health seem to be equivalent to those obtained in longer sessions of traditional aerobic training. However, there is no information about the dose of HIIT needed to obtain significant effects on cardiovascular health of children. The adoption of healthy dietary habits is also important in the prevention of obesity and cardiovascular diseases. School-based programs including physical activity and nutritional education have been recommended as important components of programs aiming to prevent obesity and cardiovascular diseases.

Official Title
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Dose-effect of HIIT on Cardiovascular Health of Children Aged 9 to 10 Years Old Participating in a School Based Multidisciplinary Intervention Program: a Pilot Study

Conditions
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Adiposity, Cardiovascular Diseases Risk

Intervention / Treatment
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* Behavioral: High intensity interval training
* Behavioral: Nutritional education


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All school children able to attend the physical education sessions of the school - Exclusion Criteria: Children with medical condition that limits physical activity

Ages Eligible for Study
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Minimum Age: 9 Years
Maximum Age: 10 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: HIIT two sessions<br>Two sessions per week of HIIT + nutritional education (1 session/week) | Behavioral: High intensity interval training<br>* Two schools with four classes/groups of 4th degree of children will participate in the pilot study (i.e., age of children 9-10 years old). One of them has two physical education (PE) sessions per week and the other has only one PE session per week. In the school with two PE sessions, two classes will be randomly assigned to HIIT (2 sessions/week) +nutrition group, and two to the nutrition group. Similarly, in the school with one PE session per week, two classes will be randomly assigned to HIIT (1 session/week) + nutrition and two classes to the nutrition goup. Both HIIT and nutritional education sessions will be integrated integrated into the physical education and sciences sessions of the schools. The duration of the intervention will be of eight weeks.<br>Behavioral: Nutritional education<br>* School-based nutritional education on healthy dietary habits<br>|
| Experimental: HIIT one session<br>One session per week of HIIT + nutritional education (1 session/week) | Behavioral: High intensity interval training<br>* Two schools with four classes/groups of 4th degree of children will participate in the pilot study (i.e., age of children 9-10 years old). One of them has two physical education (PE) sessions per week and the other has only one PE session per week. In the school with two PE sessions, two classes will be randomly assigned to HIIT (2 sessions/week) +nutrition group, and two to the nutrition group. Similarly, in the school with one PE session per week, two classes will be randomly assigned to HIIT (1 session/week) + nutrition and two classes to the nutrition goup. Both HIIT and nutritional education sessions will be integrated integrated into the physical education and sciences sessions of the schools. The duration of the intervention will be of eight weeks.<br>Behavioral: Nutritional education<br>* School-based nutritional education on healthy dietary habits<br>|
| Active Comparator: Nutritional education<br>Nutritional education (1 session/week) | Behavioral: Nutritional education<br>* School-based nutritional education on healthy dietary habits<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in cardiorespiratory fitness | 20m shuttle run test (Alpha battery) | Change from baseline cardiorespiratory fitness at eight weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Body fat | Body fat percent measured by bioimpedance | Change from baseline body fat at eight weeks | 
| Change in Ankle-brachial index | Automated simultaneous blood pressure measurement | Change from baseline Ankle-brachial index at eight weeks | 
| Change in Dietary habits | Food frequency questionnaire and 24h recall | Change from baseline Dietary habits at eight weeks | 
| Change in Muscular strength | Handgrip strength and long jump (Alpha battery) | Change from baseline Muscular strength at eight weeks | 
| Change in speed-agility | 4x10m speed agility test (Alpha battery) | Change from baseline speed agility at eight weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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school, Dose-effect, children, cardiovascular, adiposity, blood pressure, fitness, HIIT, nutritional education