The efﬁcacy of the Integrated Water Jet Channel Colonoscopy in Water Exchange Method

Study Overview
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Brief Summary
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This prospective randomized controlled trial compared integrated water jet channel colonoscopy with traditional accessory channel colonoscopy in cecal insertion time among patients undergoing WE method colonoscopy.

Detailed Description
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When the WE method colonoscopy were done with the accessory channel for both infusing and suctioning of water. The water had to be suctioned or infused alternatively and increaed the insertion time. With the new designed endoscopy that integrated a separate water jet channel for infusing water, infusing and suctioning of water can be done at the same time. Besides, water jet pumping system could provide a powerful jet to help us open the collapse lumen and keep an appropriate distance between the mucosa and the lens, thus preventing loss of visualization. It will help the colonoscopist to find the way during insertion.

Official Title
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Division of Gastroenterology, Department of Internal Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan

Conditions
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Colonoscopy, Colon Disease

Intervention / Treatment
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* Device: Water jet channel
* Device: Accessory channel


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Underwent fully sedative colonoscopy with WE method in the outpatient department Exclusion Criteria: Age < 18 years old or > 80 years old Without standard colon preparation Allergy to meperidine or propofol With a history of partial colectomy Refusal to provide written informed consent.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: A total of 120 patients were allocated into one of two groups by computerized randomization. In group A (Two-channel group), clear water was infused through the water jet channel and dirty water was sucked form the accessy channel. In group B (One-channel group), water exchange was done by using the accessory channel for both infusing and suctioning of water.
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Two-channel group<br>The colonoscopy was done with the new designed colonoscopy that integrated a separate water jet channel for infusing water. The dirty water was removed through other accessory channel. | Device: Water jet channel<br>* The separate water jet channel was used for infusing water.<br>Device: Accessory channel<br>* The accessory channel was used for infusing and/or suctioning water<br>|
| Active Comparator: One-channel group<br>The colonoscopy was done with the traditional colonoscopy. Water exchange was done by using the accessory channel for both infusing and suctioning of water. | Device: Accessory channel<br>* The accessory channel was used for infusing and/or suctioning water<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| cecal insertion time | Cecal insertion time was defined as the time from insertion into the rectum to the time when the colonoscope tip passed to a point proximal to the ileocecal valve so that the base of cecum was visible. | 2 hours | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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water exchange, water jet channel colonoscopy, colonoscopy, cecal insertion time, adenoma detection rate