Painful Breastfeeding and Bacterial or Yeast Infection

Study Overview
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Brief Summary
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The aim of this study is to investigate the prevalence of yeast and bacteria in women with breastfeeding pain and to identify signs and symptoms.

Detailed Description
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Painful breastfeeding is one of the most common reasons for early weaning. Persistent pain associated with breastfeeding can sometimes be difficult to diagnose and is a source of frustration for the breastfeeding women as well as for healthcare providers. The diagnosis of candida infection in breastfeeding women is generally based on signs and symptoms identified in case reports and without any culture. Breastfeeding pain has been described as superficial or deep in some studies. This deep pain syndrome as caused by candida or bacteria has been questioned. A few studies have cultured breast milk from women with deep breast pain and found Candida albicans infections or bacterial infections usually caused by Staphylococcus aureus. There still remains controversy and lack of evidence for candidiasis affecting the lactating breast as well as bacteria causing the pain. Ensured diagnostic methods are important due to the resistant problem with both antibiotics and antifungals. Only one study has described five key symptoms associated with candida. It was shiny, flaky nipple/areola, burning pain on the nipple/areola, non-stabbing pain or stabbing pain in the breast. The objective of this study was to investigate the prevalence of candida and bacteria in women with superficial or deep breastfeeding pain and to identify signs and symptoms linked to candida or bacteria in breast milk and nipple/areola.

Official Title
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The Prevalence of Yeast and Bacteria in Women With Painful Breastfeeding and the Diagnostic Value of Signs and Symptoms

Conditions
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Breast Infection

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: scored pain > = VAS 4 Exclusion Criteria: breastfeeding technique problems clinical signs of mastitis muscular pain breast surgery use of antibiotic or antifungal treatment during the last preceding week temperature > = 37 degree Celsius

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| 1. Deep pain group<br>1. Deep pain group; Pain in the breast | |
| 2. Superficial pain group<br>Pain on the nipple and/or aereola | |
| 3. Control group<br>No pain or other breastfeeding problems | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bacteria | Occurrence of bacteria: yes/no | Baseline (at admission) | 
| Yeast | Occurence of yeast: yes/no | Baseline (at admission) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain | VAS | Baseline (at admission) | 
| Signs | Nipple areola: cracks, red/pink, flaky, shiny, blurred, swollen, itching, smarting | Baseline (at admission) | 
| Bacteria at follow-up | Occurence of bacteria: yes/no | 2 weeks after baseline | 
| Yeast at follow-up | Occurence of yeast: yes/no | 2 weeks after baseline | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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pain, breast feeding, yeast, candida albicance, staphylococcus aureus, Signs and symptoms