Rehabilitation Gaming System for Cerebral Palsy

Study Overview
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Brief Summary
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In this study the investigators evaluate the effectivity of Virtual Reality-based rehabilitation protocols for preventing motor deterioration in patients with cerebral palsy.

Official Title
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Motor and Cognitive Training With the Rehabilitation Gaming System for Patients Affected by Cerebral Palsy

Conditions
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Cerebral Palsy, Movement Disorder

Intervention / Treatment
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* Behavioral: VR-based motor training
* Behavioral: Conventional Therapy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Children and Adult patients between 12- 50 years old diagnosed with CP according to Gross Motor Function Classification System (GMFCS). Level of disability between I and IV. Ashworth modified clinical scale < 3 (Ashworth, 1964, Bohannon Bohannon and Smith, 1987). Exclusion Criteria: Severe visual impairment. Severe cognitive impairment such as mental retardation which impedes the understanding of the task.

Ages Eligible for Study
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Minimum Age: 12 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: VR-based motor training<br>Subjects will perform 3 different training protocols in Virtual Reality that imply performing tasks of vertical and planar reaching and hitting spheres, or hockey pucks, spaced at different time, speed and color. | Behavioral: VR-based motor training<br>* Subjects will perform 3 different training protocols in Virtual Reality that imply performing tasks of vertical and planar reaching and hitting spheres, or hockey pucks, spaced at different time, speed and color.<br>|
| Active Comparator: Conventional Therapy<br>Subjects will perform conventional rehabilitation tasks for the upper-extremities that imply vertical and planar reaching movements. | Behavioral: Conventional Therapy<br>* Subjects will perform conventional rehabilitation tasks for the upper-extremities that imply vertical and planar reaching movements.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in motor function of the affected extremity as measured by MACS clinical scale |  | Change from Baseline to week 5 (End of Treatment) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in attention and visuo-perceptive and visuo-constructional apraxia as measured by the WAIS-III scale |  | Change from Baseline to week 5 (End of Treatment) | 
| Change in motor function of the affected extremity as measured by the Box and Blocks clinical scale |  | Change from Baseline to week 5 (End of Treatment) | 
| Change in the amount of use of the affected arm during training as measured by the Virtual Reality system |  | Change from Baseline to week 5 (End of Treatment) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Hemiparesis, Functional independence, Virtual Rehabilitation