Home Air Quality Impact for Adults With Asthma

Study Overview
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Brief Summary
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The purposes of this study are to determine the practicality of using home indoor air quality monitoring and a smartphone app to identify home air quality changes and how these changes affect adults with asthma.

Detailed Description
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The aims of this feasibility study are: 1) determine the feasibility and usability of: (a) ecological momentary assessment (EMA) to assess self-report residential environmental exposures and asthma symptoms, (b) home monitoring of objective environmental exposures (total volatile organic compounds [VOCs], particulates [PM2.5]), and lung function (home spirometry); 2a) assess the frequency and degree of residential environmental exposures (e.g., disinfectants/cleaners, second-hand smoke) via (a) self-reported data, and (b) home monitoring objective measures, 2b) assess the level of asthma control as indicated by self-reported asthma symptoms and lung function; and 3) explore associations of self-reported and objective measures of residential environmental exposures with self-reported and objective measures of asthma control. Participants will receive an indoor air quality monitor and a home spirometer to measure VOCs, PM2.5, and forced expiratory volume percent predicted, respectively. EMA will be collected using a personal smartphone and EMA software platform. Participants' will be sent scheduled and random EMA notifications to assess asthma symptoms, environmental exposures, lung function, and mitigation strategies. After the 14-day data collection period, participants will respond to survey items related acceptability, appropriateness, and feasibility.

Official Title
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The Changing COVID-19 Landscape: A Feasibility Study to Capture Momentary Residential Environmental Exposures and Asthma Symptoms in Adults

Conditions
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Asthma, Environmental Exposure, Home Environment Related Disease

Intervention / Treatment
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* Other: Home Air Quality


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adults who previously participated in the online Global Covid-19 and Asthma Study, indicated willingness to be contacted for future research, and reported high use of disinfectant/cleaning products since COVID-19 (≥5 per week). Current Asthma Control Test (ACT) ≤19 Own a smartphone Have a Wi-Fi/wireless internet connection in their home. Exclusion Criteria: Non-US residents Non-English speaking

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Home Air Quality|This study will assess the feasibility and usability of ecological momentary assessment (EMA) to capture the context of real time behaviors and environmental exposures that impact indoor environments. In addition, the study will assess the feasibility and usability of providing participants with a readily available indoor home air quality monitor to continuously capture total volatile organic compounds (VOCs) and particulates (PM2.5).|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Home environmental exposure to Volatile organic compounds | Degree of home exposures to volatile organic compounds as measured by the Awair home air quality monitor | Measured continuously for 14 days | 
| Home environmental exposure to particulate matter (PM) | Degree of home exposures to PM2.5 as measured by the Awair home air quality monitor | Measured continuously for 14 days | 
| Asthma control | Forced Expiratory Volume (FEV) Percent predicted as measured by ZEPHYRx home spirometer | Assessed daily for 14 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Usability of study tools | Adapted System Usability Scale, 30 items assessing usability of the ZEPHYRx home spirometer, Awair home air quality monitor, and the EMA - with response options of 1= Strongly agree to 5=Strongly Disagree | 14 days | 
| Compliance with Ecological Momentary Assessment (EMA) prompts | Frequency of responses to daily scheduled, random, and air quality triggered EMA prompts | Compliance over 4-hour periods for 14 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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volatile organic compounds, particulate matter, home air quality, asthma control, ecological momentary assessment, home air quality monitoring, smartphone technology, home spirometry