Oxygen Peripheral Saturations and Lung Surgery

Study Overview
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Brief Summary
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The purpose of this study is to compare the ability of two peripheral and non invasive devices to detect hypoxic events during one-lung ventilation and during the early postoperative period. One device measures regional cerebral oxygenation and the other muscular oxygenation. These two devices are compared to non invasive arterial saturation (SpO2), which is the gold standard.

Detailed Description
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Lung surgery is often complicated by hypoxic evants : during one-lung ventilation which leads to changes about ratio in ventilated and perfused lung areas. This blood flow redistribution promotes shunt with a decreased arterial oxygenation and possible hypoxemia. during the postoperative period. Common measure of arterial saturation through SpO2 may miss a great number of hypoxic events with regional impact because a significant decrease in SpO2 occurs for an arterial pressure in oxygen below 60 mmHg. Currently, cerebral and somatic saturation can be monitored non-invasively and continuously via optical sensors applied to the right and left forehead and to the thenar eminence. These devices may help clinicians in the detection of such hypoxemic events.

Official Title
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Evaluation of the Continuous Measurement of Tissular (StO2) and Cerebral (ScO2) Oxygenation During Lung Surgery and During the 6 First Postoperative Hours (Prospective Monocentric Study).

Conditions
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Pulmonary Surgical Procedures, Recovery Period

Intervention / Treatment
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* Device: Monitoring of tissular oxygenation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Scheduled lung surgery requiring one-lung ventilation informed consent Exclusion Criteria: Pregnant woman Neurologic or psychiatric disorders

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Pulmonary surgical patients<br>Patients submitted for scheduled lung surgery requiring one-lung ventilation | Device: Monitoring of tissular oxygenation<br>* Equanox: cerebral oxygenation by spectroscopy, near-infrared through forehead and noninvasive devices Inspectra: tissular oxygenation by spectroscopy, near-infrared through thenar and noninvasive device<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Desaturation during surgery and early postoperative recovery whatever the device. | Number of episodes | 6 hours postoperative | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Chronology between devices in case of desaturation |  | 6 hours post operative | 
| Quality of signal |  | 6 hours postoperative | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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perioperative surgery, regional oxygenation, hypoxemia, brain hypoxemia, spectroscopy, near-infrared