Effect of 3D Typing on Surgical Treatment of Hepatolithiasis

Study Overview
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Brief Summary
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According to a large amount of case affected with hepatolithiasis, we developed a typing system of Hepatolithiasis based on 3D digital conformation. And we hypothesized that it could predict a more precise construction of this disease, hence, typing by 3D conformation will improve the outcome of surgical treatment.The investigators will use a multicenter ambispective cohort study to test this hypothesis.

Detailed Description
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According to a large amount of case affected with hepatolithiasis, we developed a typing system of Hepatolithiasis based on 3D digital conformation. And we hypothesized that it could predict a more precise construction of this disease, hence, typing by 3D conformation will improve the outcome of surgical treatment.The investigators will use a multicenter ambispective cohort study to test this hypothesis. In this cohort study, two group will be enrolled to compare the outcomes.

Official Title
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Efficacy of 3D Typing and Routine Typing on Surgical Treatment of Hepatolithiasis

Conditions
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Hepatolithiasis, Surgery

Intervention / Treatment
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* Procedure: 3D typing
* Procedure: routine typing


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Aged from 18 to 65 years old Without gender restriction With a favorable liver function of Child-Pugh A to B No contraindications to surgery and anesthesia Diagnosed with Hepatolithiasis and Signed informed consent. Exclusion Criteria: Diffused type of Hepatolithiasis Impairment in liver function Severe disorders in vital organ Accompanied with tumors.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 3D typing<br>typing the patient with 3D typing system and give treatment according preestablished algorism in our center. | Procedure: 3D typing<br>* typing the patient with 3D typing system and give specific treatment<br>|
| Active Comparator: routine typing<br>typing the patient with routine typing system and give treatment according preestablished algorism in our center. | Procedure: routine typing<br>* typing the patient with routine typing system and give specific treatment<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| residual ratio of biliary stone | residual ratio of biliary stone diagnosed within 3 months | 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| postoperative complications | postoperative complications diagnosed within 6 months | 6 months | 
| residual lesions | residual lesions diagnosed within 6 months | 6 months | 
| Health economics index | Health economics index within 3 months | 3 months | 
| mortality | mortality occured within 3 months | 3 months |