Three Different Laparoscopic Approaches for Ovarian Endometrioma and the Effect on Ovarian Reserve

Study Overview
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Brief Summary
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Is ovarian reserve and fecundity rate higher with laparoscopic ovarian aspiration rather than laparoscopic ovarian cystectomy and laparoscopic ovarian de-roofing in infertile woman with ovarian endometrioma or not?

Detailed Description
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Primary objective: To assess antral follicular count before and after treatment of endometriotic cyst either by aspiration, stripping, de-roofing and bed cauterization. Secondary objectives To assess anti mullerian hormone level, follicle stimulating hormone level ,Doppler blood flow before and after treatment of endometriotic cyst either by aspiration, stripping, de-roofing and bed cauterization.

Official Title
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Three Different Laparoscopic Approaches for Ovarian Endometrioma and the Effect on Ovarian Reserve

Conditions
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Endometriosis

Intervention / Treatment
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* Procedure: laparoscopic ovarian endometriotic cyst


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Infertile woman aged 18-35 years old. Endometriotic ovarian cyst with size less than or equal 5 cm. Exclusion Criteria: Other than included criteria.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 35 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Group A; laparoscopic ovarian endometrial aspiration<br>Laparoscopic ovarian endometrial aspiration will be done for thirty patients with ovarian endometriotic cyst. . | Procedure: laparoscopic ovarian endometriotic cyst<br> <br> |
| Active Comparator: group B; laparoscopic ovarian endometrial stripping<br>Laparoscopic ovarian endometrial stripping will be done for thirty patients with ovarian endometriotic cyst. | Procedure: laparoscopic ovarian endometriotic cyst<br> <br> |
| Active Comparator: Group c laparoscopic ovarian endometrial de-roofing<br>Laparoscopic ovarian endometrial de-roofing and bed cauterization will be done for thirty patients with ovarian endometriotic cyst. | Procedure: laparoscopic ovarian endometriotic cyst<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The antral follicular count which records the number of visible ovarian follicle (2-10 mm mean diameter) seen by transvaginal ultrasound on menstrual cycle( days 2_5) | Cut point(3-10) | One month | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Anti mullerian hormone level in blood secreted by antral follicles 2-6 mm diameter in ovary | Measure in ng/ml cut point is( 0.2-0.7) | One month | 
| Follicle stimulating hormone in blood secreted by antral follicles on day 2-4 of menstrual cycle | Cut point is(10-20) measured in international unit/litre | One month |