The Relationship Between the Change of Resting Energy Expenditure and Nutritional Status .

Study Overview
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Brief Summary
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Peritonitis is a common and devastating complication in patients on peritoneal dialysis (PD). It is a known fact that persistent inflammatory state and nutritional deterioration are closely associated with increased mortality in PD patients.And resting energy expenditure(REE) is significantly increased in acute and chronic inflammation in patients with chronic kidney disease (including dialysis patients).However,it is limited to the changing trend and duration of REE in peritonitis.Investigators hypothesize that the increase in total energy consumption resulting from the increase of REE which may accompany with decreased energy intake will lead to negative energy balance and nutritional deterioration, which may affect the prognosis of patients.Therefore,a prospective cohort study will be designed to dynamically research the change of REE accompanied with the nutrition status in peritonitis and provide the basis for peritonitis management in the future.

Official Title
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The Relationship Between the Change of Resting Energy Expenditure(REE) and Nutritional Status in Peritoneal Dialysis(PD) Patients With Peritonitis.

Conditions
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Peritonitis, Resting Energy Expenditure, Nutrition

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Receiving PD for>3 months Age between 18 and 80 years Confirm diagnosis of peritonitis Exclusion Criteria: Disability Other acute complications: including systemic infections except for peritonitis, acute cardia-cerebrovascular disease in one month Active hepatitis and musculoskeletal diseases in the past Cancer and is treated with chemoradiotherapy within 1 year Severe edema of the whole body or a large amount of body cavity effusion Thyroid dysfunction History of hormonal drugs use During pregnancy or lactation Mental disorder

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The relationship between the change of REE and the change of albumin | Method: REE, indirect calorimetry | 90 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The relationship between the change of REE and the change of BMI | The relationship between the change of REE and the change of BMI during 90 days after peritonitis | 90 days | 
| The relationship between the change of REE and the change of handgrip strength | The relationship between the change of REE and the change of handgrip strength during 90 days after peritonitis | 90 days | 
| The relationship between the change of REE and the change of Fat mass | Method: REE, indirect calorimetry; Fat mass, Bioelectrical impedance | 90 days | 
| The relationship between the change of REE and the change of lean body mass | Method: REE, indirect calorimetry; lean body mass, Bioelectrical impedance | 90 days |