The Effect of Caffeine in Elderly Citizens

Study Overview
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Brief Summary
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The study investigated the effect of caffeine on physical performance in healthy citizens aged over 70 years. The main hypothesis was that 6 mg/kg caffeine would improve cycling endurance at 65% of expected maximal heart rate.

Detailed Description
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Caffeine ingestion increases the endurance of young people exercising at 60%-85% of their maximal oxygen uptake, and it also seems to improve endurance as measured by repeated sub-maximal isometric contraction and decreases the rate of perceived exertion during exercise. Although caffeine increases endurance in young people, an increase in endurance may be of greater interest in the elderly as the population of older adults with a physically active lifestyle is growing rapidly or for increasing endurance fitness through an exercise or rehabilitation program. Therefore the main hypothesis was that caffeine would improve cycling endurance at 65% of expected maximal heart rate, and the secondary hypotheses were that caffeine would improve postural stability, reaction and movement times, isometric arm flexion endurance, and walking speed, and would reduce the rate of perceived exertion after 5 minutes of cycling in healthy elderly citizens.

Official Title
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The Effect of Caffeine as Endurance Enhancing Drug in the Elderly

Conditions
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Healthy Elderly Citizens

Intervention / Treatment
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* Drug: Caffeine


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Healthy elderly individuals aged over 70 years Exclusion Criteria: Dementia or invalidating psychiatric disease General debility, angina, or other diseases that would render participation in the test program impossible Treatment with beta receptor blocking drugs, calcium-channel blocking drugs, digitalis, or nitroglycerine Acute disease and injury Diabetes Conditions that would contraindicate caffeine ingestion or participation in the test program Treatment with medication that interacts with caffeine Ingestion of caffeine containing drinks and foods 48 hours before each session

Ages Eligible for Study
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Minimum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double


Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: Caffeine|nan|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| endurance measured on an ergometer bicycle |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| postural stability |  |  | 
| reactiontime |  |  | 
| isometric endurance (armflexion) |  |  | 
| walking speed |  |  | 
| fatigue |  |  | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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caffeine, endurance, postural stability, elderly