linjc16/ctgov huggingface dataset:
Soap on a Rope Trial

Study Overview
=================
Brief Summary
-----------------
The soap on a rope behavioral trial is a school-randomized trial to determine if a disruptive cue (the soap on a rope hall pass) can influence hand washing behavior for students in Namwala District, Zambia.

Official Title
-----------------
Evaluation of Soap on a Rope Hall Pass Behavior Intervention: a School-randomized Controlled Trial

Conditions
-----------------
Hand Disinfection

Intervention / Treatment
-----------------
* Behavioral: Soap on a rope hall pass intervention


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Students in study schools who use the latrine on the day of observation Exclusion Criteria: -
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: School-randomized controlled trial
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Intervention arm<br>Intervention arm receives a training of trainers on the soap on a rope hall pass intervention. | Behavioral: Soap on a rope hall pass intervention<br>* School health and nutrition coordinators will be trained on how to make and utilize the soap on a rope hall pass to improve hand washing behavior in schools.<br>|
| No Intervention: Control arm<br>Control arm delays the training of trainers on the soap on a rope hall pass intervention until endline hand washing data has been collected. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in hand washing behavior | Students exiting the latrine will be monitored to determine if they wash their hands using soap and water. | Handwashing behavior will be monitored at three time points: baseline, 3 weeks following the intervention, and 8 weeks following the intervention. |
Surface Electromyography in Stratifying Chronic Low Back Pain.

Study Overview
=================
Brief Summary
-----------------
Surface Electromyography can be utilised to detect normal muscle electrical activity during maximum forward flexion termed Flexion Relaxation Response (FRR)

Detailed Description
-----------------
In this study, our primary objective is to assess FRR and disability (ODI) correlation protocol as an objective tool in stratifying Chronic LBP. We also would like to evaluate the relationship between FRR with pain intensity and lumbar range of motion as our secondary objective.

Official Title
-----------------
The Application Of Surface Electromyography (SEMG) In Stratifying Chronic Low Back Pain

Conditions
-----------------
Low Back Pain

Intervention / Treatment
-----------------
* Procedure: Surface Electromyography


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Participants aged between 20 - 70 years old Mechanical LBP > 6 weeks (not acute LBP) Not received any specific exercise spinal manipulation or surgery to improve LBP within the last 3 months. Exclusion Criteria: Pregnancy Radicular LBP patients or specific-spinal pathology / red-flags. Surgical intervention for the current LBP complaint (includes traumatic causes of LBP with surgical intervention) Cognitive or communication difficulty preventing active participation in exercises or communicating pain scores

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Chronic LBP<br>Will be applied Surface Electromyography | Procedure: Surface Electromyography<br>* will be applied Surface Electromyography to assess Flexion Relaxation Response<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Oswestry Low Back Pain Disability Questionnaire | Questionnaire of the functional assessment for the low back pain patient | 1 YEAR | 
| Flexion Relaxation Response (FRR) ratio | The FRR ratio was calculated from the best SEMG values obtained during Forward Lumbar Flexion & Extension | 1 YEAR | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual Analog Scale | Representing range of pain intensity from no pain on the far left to most intense pain on the far right. | 1 YEAR | 
| Gross Range of Motion | Degree of trunk motion at maximum voluntary flexion, measured by inclinometer at the level of T12 | 1 YEAR |
Thrombophilia and Migraine, Are They Related?

Study Overview
=================
Brief Summary
-----------------
Migraine was described as related to stroke in adults and children as well. Complete thrombophilic status was not study in large groups of pediatric patients. The purpose of our study is to assess the prethrombotic profile among children and teenagers diagnosed as suffering from migraine attacks.

Official Title
-----------------
Thrombophilia and Migraine, Are They Related? - A Clinical Study

Conditions
-----------------
Migraine, Thrombosis, Thrombophilia

Intervention / Treatment
-----------------
* Procedure: Blood tests


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients diagnosed as suffering from migraine according to the Neurologic criteria.

Ages Eligible for Study
-----------------
Minimum Age: 5 Years
Maximum Age: 20 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: Blood tests|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Migraine, Thrombosis, Thrombophilia
Randomized Multicenter Trial of Prehospital Initiated Facilitated Percutaneous Coronary Intervention (PCI) Versus Primary PCI in ST-segment-Elevation MI (STEMI)

Study Overview
=================
Brief Summary
-----------------
Prehospital initiated facilitation of primary percutaneous coronary intervention by fibrinolysis might be helpful in re-opening the infarct related artery prior to percutaneous coronary intervention. This studies tests the hypothesis that prehospital initiated facilitated PCI is superior to primary percutaneous coronary intervention with respect to infarct size.

Detailed Description
-----------------
Patients with STEMI with symptoms < 3 hours are randomized in the region of Leipzig to either prehospital full-dose fibrinolysis (+ASA, Clopidogrel and heparin) with subsequent facilitated percutaneous coronary intervention or to primary percutaneous coronary intervention (after ASA + heparin + clopidogrel). Patients undergo cardiac magnetic resonance for assessment of infarct size early at day 1-4 after randomization.

Official Title
-----------------
Randomized, Controlled Multicenter Trial of Prehospital Initiated Facilitated PCI Versus Primary PCI in Patients With STEMI LIPSIA-STEMI Trial

Conditions
-----------------
Myocardial Infarction

Intervention / Treatment
-----------------
* Drug: fibrinolysis
* Procedure: Primary PCI


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Angina pectoris < 3 hours ST-elevation myocardial infarction Exclusion Criteria: Active bleeding Active gastric ulcus Previous stroke Uncontrolled hypertension (> 200 mmHg) Cerebral surgery < 8 weeks Major surgery < 4 weeks Malignancy Treatment with coumarines Pregnancy

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Prehospital facilitated PCI<br> | Drug: fibrinolysis<br>* Primary PCI<br>* Other names: Primary PCI;|
| Active Comparator: Primary PCI<br> | Procedure: Primary PCI<br>* Primary PCI<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Infarct size and microvascular obstruction assessed by MRI |  | 1-6 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Clinical endpoints (bleeding, death, Re-MI, stroke) |  | 30 days | 
| ST-segment resolution |  | 90 min | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
infarction, facilitated PCI, primary PCI, infarct size, fibrinolysis, ST-elevation myocardial infarction (STEMI)
Dexamethasone Intravitreal Implant (Ozurdex®) for Recurrent Vogt-Koyanagi-Harada (VKH) Disease Posterior Uveitis

Study Overview
=================
Brief Summary
-----------------
VKH disease is a vision threatening condition.The investigators consider that ozurdex intravitreal implant is an effective line of treatment in recurrent VKH posterior uveitis.

Detailed Description
-----------------
Baseline ,and postoperative 1 ,6 ,12 and 24 months full ophthalmic examination was done. Procedure included intravitreal injection of Dexamethasone implant 0.7 mg (Ozurdex(®); Allergan, Inc, Irvine, CA)

Official Title
-----------------
Long Term Efficacy of Dexamethasone Intravitreal Implant (Ozurdex®) in Treatment of Recurrent VKH Uveitis

Conditions
-----------------
Posterior Uveitis

Intervention / Treatment
-----------------
* Drug: Dexamethasone Ophthalmic implant


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Recurrent VKH posterior uveitis Exclusion Criteria: retinal pathology, other causes of posterior uveitis

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: Dexamethasone Ophthalmic implant|intravitreal injection of ozurdex implant|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Best corrected visual acuity (BCVA) | Change in BCVA | 2 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| optical coherence tomography (OCT) foveal thickness | changes in central foveal thickness | 2 years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
dexamethasone;VKH
Expanded Access for CC-486

Study Overview
=================
Brief Summary
-----------------
This is an expanded access program (EAP) for eligible participants designed to provide access to CC-486.

Official Title
-----------------
Expanded Access for CC-486

Conditions
-----------------
Acute Myelogenous Leukemia (AML)

Intervention / Treatment
-----------------
* Drug: CC-486


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: -Adult patients with documented acute myelogenous leukemia (AML) in their first complete remission (CR) or complete remission with incomplete blood count recovery (CRi) following induction therapy with or without consolidation treatment, who seek treatment with CC-486 as monotherapy to maintain their CR or CRi. Exclusion Criteria: Patients with AML in CR/CRi who plan to proceed to or are waiting for a bone marrow transplant Patients who have received a bone marrow transplant for the treatment of AML Treatment of AML patients with relapse or refractory disease Pregnant or breast-feeding females Patient meets enrollment criteria and can participate in a disease-specific clinical trial

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: CC-486|Oral azacitidine administered as directed by treating physician.|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Expanded Access, Compassionate Use
Customized PRK With Mitomycin Versus Customized Lasik for Myopic Astigmatism

Study Overview
=================
Brief Summary
-----------------
The present study was designed to compare the use of mitomycin in PRK for the treatment of refractive errors and to compare these results to customized Lasik

Official Title
-----------------
Customized PRK With Mitomycin Versus Customized Lasik for Myopic Astigmatism

Conditions
-----------------
Refractive Errors

Intervention / Treatment
-----------------
* Procedure: Prk with mitomycin vs Lasik


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Myopia or compound myopic astigmatism, stable refractive error, no associated eye disease Exclusion Criteria: Diabetes, autoimmune diseases, topographic abnormalities

Ages Eligible for Study
-----------------
Minimum Age: 21 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: Prk with mitomycin vs Lasik|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| visual acuity |  |  | 
| refractive errors |  |  | 
| topography patterns |  |  | 
| aberrometry data |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| subjective evaluation |  |  | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
myopia, excimer laser
Effect of Chlorhexidine Gel on Bacterial Count During Fixed Orthodontic Treatment

Study Overview
=================
Brief Summary
-----------------
This study investigates the benefit of using chlorhexidine gel as an antimicrobial agent in orthodontic patient to reduce caries risk and the possible consequential effect of this use on the orthodontic brackets used for the treatment. The investigators hypothesis is that chlorhexidine gel use can reduce caries risk in orthodontic patients with out causing damage to the bonded ceramic or metal orthodontic brackets.

Official Title
-----------------
Effect of Chlorhexidine Gel on Bacterial Count and Orthodontic Brackets During Fixed Orthodontic Treatment; In-vivo & In-vitro Study

Conditions
-----------------
Orthodontic Appliance Complication, Dental Caries

Intervention / Treatment
-----------------
* Drug: Chlorhexidine gluconate


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients' age range from 18-30 years. Fixed orthodontic treatment. All the patients are at the end of leveling and alignment stage. Initial bacterial count indicates high caries risk. All patients will be given good oral hygiene instruction at the first visit. The subjects had not taken antibiotics for at least 6 weeks before saliva sampling or during the experimental period. All subjects used a fluoride dentifrice twice a day. Exclusion Criteria: Patients' age more or less then the age range specified. Removable orthodontic treatment. Patients at early stages of leveling and alignment. Initial bacterial count indicates low caries risk. Subjects that have taken antibiotics for at least 6 weeks before saliva sampling.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 30 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: chlorhexidine gel<br>anti microbial agent that prevents the formation of plaque and reduces caries risk | Drug: Chlorhexidine gluconate<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| mutants streptococcus count | measures the change in bacterial count before and after application of the gel | 48 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| friction | measures static and dynamic friction in Newton | 2 minutes | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
chlorhexidine gel, orthodontic brackets, orthodontic patients, bacterial count, friction
Short Term Effects of HMG-CoA Reductase Inhibition (Atorvastatin)on Renal Hemodynamics, Tubular Function and Vasoactive Hormones on Healthy Subjects

Study Overview
=================
Brief Summary
-----------------
We wanted to test the shortterm effects of HMG-CoA reductase inhibition (atorvastatin) on renal hemodynamics, renal tubular function and vasoactive hormones on healthy subjects.

Official Title
-----------------
Short Term Effects of HMG-CoA Reductase Inhibition (Atorvastatin)on Renal Hemodynamics, Tubular Function and Vasoactive Hormones on Healthy Subjects.

Conditions
-----------------
Healthy

Intervention / Treatment
-----------------
* Drug: HMG-CoA reductase inhibition (atorvastatin)


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Both men and women Age: Between 20-50 BMI<30 Exclusion Criteria: Cl. signs or history of disease of heart, lungs, kidneys or endocrine organs. Abnormal lab. tests( haemoglobin, pl. sodium, pl. potassium, pl.creatinine, pl.bilirubin, pl.ALAT, pl. cholesterol, blood glucose) Albuminuria or glucosuria Cancer Art. hypertension Alcohol abuse Med. treatment, except oral contraceptives Pregnancy or breast feeding Blood donation less than 1 month before study

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 50 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double


Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: HMG-CoA reductase inhibition (atorvastatin)|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| GFR |  |  | 
| RPF |  |  | 
| FEna |  |  | 
| FELi |  |  | 
| CLna |  |  | 
| CLli |  |  | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
HMG-COA reductase inhibition, GFR, RPF, FE, CL
Effect on Shoulder Training Using Rehabilitation Robot for Stroke Patients

Study Overview
=================
Brief Summary
-----------------
The purpose is to study the effect of rehabilitation robot on shoulder training for stroke patients.

Official Title
-----------------
Rehabilitation Robot for Upper Limbs, Component Project 5: Effect on Shoulder Training Using Rehabilitation Robot for Stroke Patients

Conditions
-----------------
Stroke

Intervention / Treatment
-----------------
* Device: Rehabilitation Robot for Upper Limb Dysfunction (NTUH Model One)


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: stroke (1-3 months) Brunnstrom Stage II-III single, unilateral Exclusion Criteria: aphasic shoulder impairment severe osteoporosis

Ages Eligible for Study
-----------------
Minimum Age: 50 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: shoulder training, rehabilitation robot<br> | Device: Rehabilitation Robot for Upper Limb Dysfunction (NTUH Model One)<br>* Use an intelligent robot to assist upper limb rehabilitation.<br>* Other names: self-developed robotic arm;|
| No Intervention: control group<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Barthel index, |  | 1 year | 
| Modified Asworth Scale |  | 1 year | 
| STREAM and PASS scales |  | 1 year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| shoulder range of motion, VAS |  | 1 year |