Effects of WB-EMS in Ulcerative Colitis Patients

Study Overview
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Brief Summary
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The purpose of this study is to determine the effect of 12 weeks of WB-EMS either applicated passive in a supine resting position or active during slight movements compared with a non-training control group on body composition, muscle strength and QoL in patients with ulcerative colitis. Our main hypothesis is that active WB-EMS application is significantly more favorable to address our primary endpoints compared with passive application. Our secondary hypothesis is that passive WB-EMS application is significantly more favorable to address our primary endpoints compared with non-training control.

Official Title
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Effects of Different Types of Whole Body Electromyostimulation (WB-EMS) Application on Body Composition, Muscle Strength and Quality of Life in Patients With Ulcerative Colitis

Conditions
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Ulcerative Colitis

Intervention / Treatment
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* Other: active Whole Body Electromyostimulation
* Other: Passive WB-EMS
* Device: WB-EMS application


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: ulcerative colitis ambulatory subjects Exclusion Criteria: variables that conflicts with WB-EMS application (e.g. cardiac pacemakers) absence of more than two weeks during the interventional period.
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: active WB-EMS<br>2 sessions/week with 20 min of active WB-EMS application | Other: active Whole Body Electromyostimulation<br> <br> Device: WB-EMS application<br> <br> |
| Experimental: Passive WB-EMS<br>2 sessions/week with 20 min of passive WB-EMS application in a resting supine position | Other: Passive WB-EMS<br> <br> |
| No Intervention: Inactive Control Group<br>sedentary non-training control group | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Lean Body Mass | Lean Body Mass (LBM) and Appendicular Skeletal Muscle Mass (ASMM) as assessed by Dual-Energy-x-Ray Absorptiometry (DXA) | 12 weeks, baseline to 12 week follow-up | 
| Isokinetic muscle strength | Isokinetic muscle strength of the leg extensors and - flexors as assessed by a isokinetic leg strength | 12 weeks, baseline to 12 week follow-up | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Quality of Life (QoL) | QoL as assessed by inflammatory bowel disease questionnaire (IBDQ-D) and Depression Scores | 12 weeks, baseline to 12 week follow-up | 
| Isometric muscle strength | Isometric strength of the trunk flexors. | 12 weeks, baseline 12 week follow-up | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Whole Body Electromyostimulation, Inflammatory Bowel Disease, Lean Body Mass, Muscle Strength