NutriCovid30 : Nutritional Evaluation for Covid-19 Infection at D30

Study Overview
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Brief Summary
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Describe the main clinical features impacting the food intake, and therefore the nutritional status of a population infected by a coronavirus.

Detailed Description
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The recent Covid-19 outbreak has brought USA, European, British and French nutrition learned societies to publish recommendations for the nutritional management of patients infected with the SARS-CoV-2. They reminded that there is a risk of malnutrition for that population. The emergency and rapid evolution in the situation have led to severe cases of anosmia, ageusia, diarrhea, odynophagia, anorexia etc.. Some of the first patients cured from Covid-19 have lost up to 10 kgs. To this day, there is no available information regarding either nutritional characteristics or nutritional interventions (enteral or parenteral nutrition, oral nutritional supplements, dietary supplementations) for Covid-19 patients. The objective of this study is to describe nutritional consequences of the Covid-19 infection for adults, 30 days after their discharge from hospital, as well as the nutritional care they received. Type and proportion of chronic diseases will be assessed in this trial.

Official Title
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Evaluation of the Repercussions of the Coronavirus (Covid 19) Infection on Nutritional Health Status and Nutritional Care : an Observational French Cohort Study One Month After Their Discharge From Hospital

Conditions
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COVID-19

Intervention / Treatment
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* Other: Interview


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 30 days or more after discharge from hospital for Covid-19 Patient received information about the trial and gave his/her consent Patient capable of answering the phone (alone or with some help) Exclusion Criteria: Patient diseased impossibility to collect information from the patient or one of his/her relatives Patient protected by the French Public Health Code (art. L1121-5 à L1121-8)

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Prospective cohort University Hospital, Grenoble<br>Semi-structured survey administered on the phone, once, one month after discharge from hospital. The interview will not be recorded. | Other: Interview<br>* A survey was created, aiming to collect information about prior history of chronic disease, the Self-Evaluation of Food Intake, dysregulations (anosmia, ageusia...), anthropometric data, food data during and after hospitalisation, healthcare consumption since the discharge from hospital<br>|
| Prospective cohort University Hospital, Toulouse<br>Semi-structured survey administered on the phone, once, one month after discharge from hospital. The interview will not be recorded. | Other: Interview<br>* A survey was created, aiming to collect information about prior history of chronic disease, the Self-Evaluation of Food Intake, dysregulations (anosmia, ageusia...), anthropometric data, food data during and after hospitalisation, healthcare consumption since the discharge from hospital<br>|
| Prospective cohort University Hospital, Nancy<br>Semi-structured survey administered on the phone, once, one month after discharge from hospital. The interview will not be recorded. | Other: Interview<br>* A survey was created, aiming to collect information about prior history of chronic disease, the Self-Evaluation of Food Intake, dysregulations (anosmia, ageusia...), anthropometric data, food data during and after hospitalisation, healthcare consumption since the discharge from hospital<br>|
| Prospective cohort University Hospital, Rennes<br>Semi-structured survey administered on the phone, once, one month after discharge from hospital. The interview will not be recorded. | Other: Interview<br>* A survey was created, aiming to collect information about prior history of chronic disease, the Self-Evaluation of Food Intake, dysregulations (anosmia, ageusia...), anthropometric data, food data during and after hospitalisation, healthcare consumption since the discharge from hospital<br>|
| Prospective cohort Hospices Civils de Lyon<br>Semi-structured survey administered on the phone, once, one month after discharge from hospital. The interview will not be recorded. | Other: Interview<br>* A survey was created, aiming to collect information about prior history of chronic disease, the Self-Evaluation of Food Intake, dysregulations (anosmia, ageusia...), anthropometric data, food data during and after hospitalisation, healthcare consumption since the discharge from hospital<br>|
| Prospective cohort Assistance Publique Hôpitaux de Paris<br>Semi-structured survey administered on the phone, once, one month after discharge from hospital. The interview will not be recorded. | Other: Interview<br>* A survey was created, aiming to collect information about prior history of chronic disease, the Self-Evaluation of Food Intake, dysregulations (anosmia, ageusia...), anthropometric data, food data during and after hospitalisation, healthcare consumption since the discharge from hospital<br>|
| Prospective cohort University Hospital, Rouen<br>Semi-structured survey administered on the phone, once, one month after discharge from hospital. The interview will not be recorded. | Other: Interview<br>* A survey was created, aiming to collect information about prior history of chronic disease, the Self-Evaluation of Food Intake, dysregulations (anosmia, ageusia...), anthropometric data, food data during and after hospitalisation, healthcare consumption since the discharge from hospital<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluation of food intake at 1 month after discharge from hospital for COVID | Self assessment on the SEFI (Self-Evaluation of Food Intake) scale at one month after hospital discharge: 0 corresponds to the worsen score (no ingesta) and 10 corresponds to the best (same ingesta than before the disease) | one month after hospital discharge | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Weight variation during the infection | Self-reported weight in kilograms, or in the absence of self-reported variations before the disease, during hospitalisation, at hospital discharge, one month after hospital discharge | one month after hospital discharge | 
| Clinical signs limiting food intake | Effect of these factors (anorexia, dysgeusia, Ear Nose and Throat pain, swallowing disorders, intestinal transit disorders...) on SEFI and weight | one month after hospital discharge | 
| Factors limiting food intake | Effect of these factors (supply difficulties, disease-related food disgust, limiting food habits or prior diet, hydration difficulties, need for help) on SEFI and weight | one month after hospital discharge | 
| Implemented nutritional strategy | Effect of nutritional strategy and interventions that were implemented (nutritional advice, adapted meals, oral nutritional supplementation, enteral and parenteral nutrition during hospitalisation and one month after hospital discharge) on SEFI and weight | one month after hospital discharge | 
| Pre-existing chronic disorders | Effect of pre-existing chronic disorders (pulmonary, chronic inflammatory bowel disease, cardio-vascular disease, diabetes, obesity, cognitive disorders, immunodepression, cancer, inflammatory joint disorder) on SEFI and weight | one month after hospital discharge | 
| Covid-19 repercussions | Quantifying unscheduled consultations or hospitalisations in the month following discharge from hospital | one month after hospital discharge |