Predictive Factors for a Successful Return to Run After ACL-R

Study Overview
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Brief Summary
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After anterior cruciate ligament (LCA) rupture, the recommended treatment for athletes is the surgical reconstruction of the ligament (ACL-R), followed by a long rehabilitation period. The results of this treatment are sub-optimal with a low rate of return to pre-injury level of sport, a high risk of reinjury and early knee osteoarthritis. To improve treatment outcomes, researchers and clinicians recommend optimizing rehabilitation protocols. They recommend individualizing rehabilitation progression based on objective criteria. However, current defined criteria relied on experts' opinions and not scientific validation. Return to run after ACL reconstruction is an important rehabilitation milestone. It often means the beginning of the return to sport continuum. A successful return to run is therefore crucial for both the patient and clinician. In this study, the investigators aim to determine the predictive outcomes for a successful return to run after ACL-R.

Official Title
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Predictive Factors for a Successful Return to Run After Anterior Cruciate Ligament Reconstruction and Underlying Bio-mechanical Factors

Conditions
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ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION

Intervention / Treatment
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* Other: Retrun to run protocol


Participation Criteria
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Eligibility Criteria
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Experimental group Inclusion Criteria: ACL-R 3 to 4 months ago Exclusion Criteria: already returned to run multiple ligament lesions Control group Inclusion Criteria: - healthy person Exclusion Criteria: history of ACL lesion or reconstruction history of knee injury injured in the last year

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: ACL-R<br> | Other: Retrun to run protocol<br>* Progressive return to run protocol for patients after ACL-R<br>|
| No Intervention: Control<br> | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Muscular strength assessment | Quadriceps, hamstring and gluteus strength assessment with handheld dynamometer (N) | Day 0 | 
| Modified Y-balance test | Modified Y-balance test (m) | Day 0 | 
| step-down test | endurance test, number of repetition | Day 0 | 
| Self-reported outcomes: ACL-RSI | ACL-RSI: 0-100 | Day 0 | 
| Self-reported outcomes: IKDC | IKDC: 0-100 | Day 0 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Running kinematic | knee kinematic (degree) | Day 0 and Day 14 | 
| Running kinetic | kinetic (N) | Day 0 and Day 14 | 
| Knee joint contact force | knee joint contact force (N) | Day 0 and Day 14 |