Evaluation of Pericapsular Nerve Group Block on Positioning Pain for Spinal Anesthesia in Hip Fracture Patients

Study Overview
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Brief Summary
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The purpose of this study is to evaluate of analgesic effects of pericapsullar nerve group block which is performed preoperatively to assist positioning patients for performance of spinal anesthesia.

Official Title
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Evaluation of Pericapsular Nerve Group Block on Positioning Pain for Spinal Anesthesia in Hip Fracture Patients

Conditions
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Pain, Acute

Intervention / Treatment
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* Procedure: PENG Block
* Drug: Conventional opioid analgesia (Fentanyl)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: hip fracture aged between 35 and 90 years old Exclusion Criteria: contraindications for spinal anesthesia and PENG block impaired cognition or dementia multiple fractures any previous analgesic administration during the last 12 hours

Ages Eligible for Study
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Minimum Age: 35 Years
Maximum Age: 90 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: PENG Block<br>For patients with hip fracture and having hip surgery this study evaluates the analgesic effects of Pericapsular Nerve Group (PENG) block for positioning before spinal anesthesia. | Procedure: PENG Block<br>* Pericapsular Nerve Group Block<br>|
| Active Comparator: Control<br>in this group, standardised opioid doses (drug: Fentanyl) will be used for analgesia for positioning pain | Drug: Conventional opioid analgesia (Fentanyl)<br>* standardised intravenous opioid<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain scores on the Numeric Rating Scale (NRS) | Changes in Numeric Rating Scale (NRS) at rest and on movement will be recorded at intervals. NRS is a unidimensional measure of pain intensity in adults. The NRS is a segmented numeric version of the visual analog scale (VAS) in which a respondent selects a whole number (0-10 integers) that best reflects the intensity of his/her pain. The 11-point numeric scale ranges from '0' representing one pain extreme (e.g. no pain) to '10' representing the other pain extreme (e.g. pain as bad as you can imagine or worst pain imaginable). | Group A: 5 minutes after intervention (intravenous opioid), Group B: 20 minutes after intervention (PENG block) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Duration of spinal anesthesia performance | It will be measured in minutes, from the start of positioning maneuvers to the spinal needle removal | Group A: 5 minutes after intervention (intravenous opioid), Group B: 20 minutes after intervention (PENG block) | 
| Quality of patient's position | The position will be characterized as unsatisfactory, satisfactory, good or very good | Group A: 5 minutes after intervention (intravenous opioid), Group B: 20 minutes after intervention (PENG block) | 
| Analgesic consumption | In the postoperative period, patients will be given opioids according to their pain density with a patient-controlled device, and the daily Morphine consumption in Patient Controlled Analgesia device will be collected and compared between groups. | 24 hours | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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hip fracture, postoperative analgesia, positioning pain