A Follow-up Survey to Compare Stable Dosing (SERETIDE) With SYMBICORT, SMART, Maintenance and Reliever Therapy in One Inhaler in Moderate and Severe Asthmatics.

Study Overview
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Brief Summary
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The purpose with this study is to describe in detail the control or lack of control of asthma, based on two different dosing strategies, regular treatment with SERETIDE in a stable dosing with short acting beta-2 agonists as needed, or maintenance treatment with SYMBICORT and using the same inhaler with SYMBICORT as needed.

Detailed Description
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The purpose with this study is to describe in detail the control or lack of control of asthma, based on two different dosing strategies. No therapy intervention is made with existing prescribed medications (SERETIDE or SYMBICORT), but evaluations outside standard care is made by evluations with diary cards, questionnaires, PEF evaluations and spirometry which is regarded as the intervention by the Swedish Authorities.

Official Title
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Follow-up Survey to Compare Stable Dosing (SERETIDE) With SYMBICORT SMART, Maintenance and Reliever Therapy in One Inhaler in Moderate and Severe Asthmatics.

Conditions
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Asthma

Intervention / Treatment
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* Other: Spirometry, PEF measurements and diary cards to evaluate control of Asthma


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: written informed consent 18 years or above able to fill in questionnaires and perform PEF measurements asthma diagnosis and prescribed SERETIDE or SYMBICORT, either regular treatment using SERETIDE in a stable dosing and short acting B2 agonists as needed, or maintenance treatment with SYMBICORT but also using same inhaler SYMBICORT as needed Exclusion Criteria: no other lung disease neurological disease with psychological handicap cerebro-vascular disease with handicap un-stable cancer known or planned pregnancy during the time of the study subjects who have serious uncontrolled disease

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Stable dosing with SERETIDE, short acting B-2agonist as needed<br>Regular treatment with SERETIDE in a stable dosing with short acting beta-2 agonists as needed | Other: Spirometry, PEF measurements and diary cards to evaluate control of Asthma<br>* No intervention is made with the existing therapy, but patient will perform spirometry and PEF evaluations together with a registration of control of asthma in diary cards and health economic parameters in questionnaires<br>|
| Experimental: Maintenance treatment with SYMBICORT and SYMBICORT as needed<br>Maintenance treatment with SYMBICORT and using the same inhaler with SYMBICORT as needed | Other: Spirometry, PEF measurements and diary cards to evaluate control of Asthma<br>* No intervention is made with the existing therapy, but patient will perform spirometry and PEF evaluations together with a registration of control of asthma in diary cards and health economic parameters in questionnaires<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| asthma control based on GINA guidelines from 2007. |  | 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Quality of Life, Health economics and exacerbations |  | 3 months |