Timing Effect of Ultrasound-Guided PVB After Robotic Cardiac Surgery

Study Overview
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Brief Summary
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This study is to evaluate whether the administration of ultrasound-guided paravertebral block (PVB) after surgery would produce better postoperative pain control and fast postoperative recovery after Robotic cardiac surgery. Half of participants will receive PVB before surgery, while the other half will receive PVB at the end of surgery.

Detailed Description
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Ultrasound-guided PVB (either before surgery, or after surgery) is the standard postoperative pain management for Robotic cardiac surgery. This technique is to inject local anesthetic (numb medication) around nerve to decrease pain. But the optimal time of PVB is unknown. The administration of PVB before surgery can help pain control during the surgery and after surgery. But the duration of PVB could be reduced because surgery itself can last 5-6 hrs. The PVB after surgery will not provide pain control during surgery, but may provide longer pain control after surgery, and may help participants faster recovery after surgery.

Official Title
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Randomized, Single-Blinded Study to Evaluate the Timing Effect of Ultrasound-Guided Paravertebral Block in Patients Undergoing Robotic Mitral Valve Repair Procedure

Conditions
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Nerve Block, Cardiac Surgery

Intervention / Treatment
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* Procedure: PVB block


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age ≥ 18 yrs ASA I-IV Either gender Exclusion Criteria: Refusal to participate in the study Age< 18 yrs Contraindications to regional blockage including but not limited to: Patient refusal to regional blockade Infection at the site of needle insertion Systemic infection Bleeding diathesis or coagulopathy

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: PVB before surgery<br> | Procedure: PVB block<br>* PVB block before surgery versus after surgery<br>|
| Active Comparator: PVB after surgery<br> | Procedure: PVB block<br>* PVB block before surgery versus after surgery<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Durations of ICU and hospitalization | Duration (days) of ICU stay, and duration of hospital stay | 2-6 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain intensity measure | self reported pain intensity at every 4 hour while in the ICU. It is a scored 0-10 (0 = no pain, 10 + pain as bad as can be) | 2-3 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Postoperative pain