Initial CT Findings and CO-RADS Stage in COVID-19

Study Overview
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Brief Summary
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This study aims to determine whether patients with different real-time reverse transcriptase-polymerase chain reaction (PCR), chest computed tomography (CT) and laboratory findings have different clinical outcomes.

Detailed Description
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This study aims to determine the rates of PCR positivity and CT findings in hospitalized patients with a diagnosis of COVID-19, to determine whether there is a difference in mortality and need for ICU between patients grouped according to the PCR positivity and presence of CT findings, and to evaluate the effect of the CO-RADS stage on these outcomes. Moreover, it is to compare the effects of inflammation and coagulation markers and CO-RADS stage on the severity of the disease

Official Title
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Comparison of Initial CT Findings and CO-RADS Stage in COVID-19 Patients With PCR, Inflammation and Coagulation Parameters in Diagnostic and Prognostic Perspectives

Conditions
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Covid19, SARS-CoV Infection, Pneumonia, Viral

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Aged 18 years and over, Having SARS-CoV-2 RT-PCR test and chest CT examinations performed at the time of application or within 24 hours after admission RT-PCR positivity in nasopharyngeal swabs sample, and/or the presence of clinical and laboratory findings of SARS-CoV-2 infection and/or the presence of COVID-19-compatible radiological findings in chest CT, and being diagnosed with COVID-19 Exclusion Criteria: Patients with negative SARS-CoV-2 PCR test, pneumonia on CT but not given Covid-19 treatment by not considering Covid-19 by their doctor will not be included. Patients whose data are not available Patients with poor CT image quality Patients who were transferred to another hospital

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| COVID-19 patients in hospital<br>All patients aged 18 years and over, positive for SARS-CoV-2 PCR test and / or Covid-19 treatment with signs of Covid-19 disease on CT | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| mortality | mortality during hospitalization and within 14 days after hospitalization | up to 30 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| need for intensive care | need for intensive care during hospitalization and within 30 days after hospitalization | up to 30 days | 
| need for intenvasive mechanical ventilation | need for intenvasive mechanical ventilation during hospitalization and within 30 days after hospitalization | up to 30 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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COVID-19, SARS-CoV2 RT-PCR Testing, Thorax, Computerized Tomography, Mortality, Prognosis