Ultrasound Guided Erector Spinae Plane Block Versus Quadratus Lumborum Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Sleeve Gastrectomy

Study Overview
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Brief Summary
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Postoperative pain control is a signiﬁcant challenge in medical practice. Inadequate pain control could decrease patient's satisfaction, delay postoperative ambulation, increase the incidence of pulmonary and cardiac complications and cause the development of chronic postoperative pain. Laparoscopic surgical techniques could decrease postoperative pain and opioid consumption. The addition of regional techniques to general anesthesia showed better pain management and less consumption of opioids compared to the traditional techniques. The aim of this study is to compare the effectiveness of ultrasound guided erector spinae plane block versus quadratus lumborum block regarding postoperative analgesia in patients undergoing laparoscopic sleeve gastrectomy.

Official Title
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A Randomized Controlled Trial for Postoperative Analgesia in Patients Undergoing Laparoscopic Sleeve Gastrectomy: Ultrasound Guided Erector Spinae Plane Block Versus Quadratus Lumborum Block

Conditions
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Post Operative Pain

Intervention / Treatment
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* Other: Group Erector Spinae Plane Block (ESPB)
* Other: Group Quadratus Lumborum Block (QLB)
* Other: Group (C) (Control group)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients with free medical history or controlled hypertension and/ or diabetes scheduled for elective laparoscopic sleeve gastrectomy. BMI > 35 kg/ m2 Exclusion Criteria: Patients unfit for surgery or refuse to sign the consent of regional block. Patients with known coagulation defects. Patients with known hypersensitivity to bupivacaine. Patients with infection at the site of injection. Conversion of laparoscopic surgery to laparotomy

Ages Eligible for Study
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Minimum Age: 21 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Group Erector Spinae Plane Block (ESPB)<br> | Other: Group Erector Spinae Plane Block (ESPB)<br>* Patients will receive general anesthesia initially then bilateral ESPB with a total volume of (0.3-0.4 ml/kg LBW) of bupivacaine 0.25% will be performed (not exceeding toxic dose) 150 mg <br>|
| Active Comparator: Group Quadratus Lumborum Block (QLB)<br> | Other: Group Quadratus Lumborum Block (QLB)<br>* Patients will receive general anesthesia initially then bilateral QLB with a total volume of (0.3-0.4 ml/kg LBW) of bupivacaine 0.25% will be performed not exceeding toxic dose150 mg <br>|
| Other: Group (C) (Control group)<br> | Other: Group (C) (Control group)<br>* Where patients will be operated under general anesthesia.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Time to first requested rescue analgesia(Minutes) | Time to first requested rescue analgesia(Minutes) | 24 hours postoperatively |