Dietary Protein Requirement of Elderly Men and Women

Study Overview
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Brief Summary
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The purpose of this study was to assess the effect of age on the estimated average requirement and adequate allowance for dietary protein.

Official Title
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Dietary Protein Requirement of Elderly Men and Women

Conditions
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Age

Intervention / Treatment
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* Other: Lower Protein
* Other: Medium Protein
* Other: Higher Protein


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age: 21-46 years, 63-81 years old Not diagnosed with diabetes or metabolic syndrome Clinically normal blood laboratory values Exclusion Criteria: Age: 21 years of younger, 47-62 years old, and 82 years and older BMI: 20-29 kg/m Weight stable: <2kg change within the last 3 months Physical Activity: constant habitual pattern, no deviation >1x week of 30/minute sessions within the last 3 months Clinically abnormal values: Blood Urine Also, exclude any: Using meds that would influence appetite Using any anti-inflammatory steroid medications Has a joint replacement A medical condition that might place them at risk for participating in the study or interfere with successful completion of the study

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 1<br>Young men, age 21-46 years. | Other: Lower Protein<br>* Each subject completed an 18-day periods (trials) of strict dietary control of consuming a lower protein diet.<br>Other: Medium Protein<br>* Each subject completed an 18-day periods (trials) of strict dietary control of consuming a medium protein diet.<br>Other: Higher Protein<br>* Each subject completed an 18-day periods (trials) of strict dietary control of consuming a higher protein diet.<br>|
| Experimental: 2<br>Old Men, age 63-81 years. | Other: Lower Protein<br>* Each subject completed an 18-day periods (trials) of strict dietary control of consuming a lower protein diet.<br>Other: Medium Protein<br>* Each subject completed an 18-day periods (trials) of strict dietary control of consuming a medium protein diet.<br>Other: Higher Protein<br>* Each subject completed an 18-day periods (trials) of strict dietary control of consuming a higher protein diet.<br>|
| Experimental: 3<br>Young women, age 21-46 years. | Other: Lower Protein<br>* Each subject completed an 18-day periods (trials) of strict dietary control of consuming a lower protein diet.<br>Other: Medium Protein<br>* Each subject completed an 18-day periods (trials) of strict dietary control of consuming a medium protein diet.<br>Other: Higher Protein<br>* Each subject completed an 18-day periods (trials) of strict dietary control of consuming a higher protein diet.<br>|
| Experimental: 4<br>Old women, age 63-81 years. | Other: Lower Protein<br>* Each subject completed an 18-day periods (trials) of strict dietary control of consuming a lower protein diet.<br>Other: Medium Protein<br>* Each subject completed an 18-day periods (trials) of strict dietary control of consuming a medium protein diet.<br>Other: Higher Protein<br>* Each subject completed an 18-day periods (trials) of strict dietary control of consuming a higher protein diet.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To determine the dietary protein requirement of older men and women. |  | 57 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| What is the lowest amount of protein that a man or women should eat each day to help him or her stay healthy? |  | 57 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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assess the effect of age on the EAR and RDA for protein