Meaning of Life in HIV-infected Youths

Study Overview
=================
Brief Summary
-----------------
Logotherapy has never been evaluated in HIV-infected teenagers. In this study, we will evaluate the meaning of life by using The Purpose in Life Test and the affect of logotherapy in HIV infected youth at HIV-NAT, Thai Red Cross AIDS Research Centre and King Chulalongkorn Memorial Hospital.

Detailed Description
-----------------
In the HAART era, HIV infected children can live longer and will grow up to become teenagers. However, some may develop psychosocial problems because they have lost family members, experienced poverty, social discrimination etc. Being a normal teenager is tough and is the most complex period of his/her life. This is the period when most teenagers will find their identity and reasons for living. Therefore it is believed that interventions may help HIV-infected teenagers better deal with life. For this study, logotherapy, a therapy that will help a person to discover his/her purpose in life, live meaningful life, and attain self-esteem was used. The success of the intervention was evaluated by using The Purpose in Life Test.

Official Title
-----------------
Meaning in Life of Youth Infected With HIV

Conditions
-----------------
Meaning of Life

Intervention / Treatment
-----------------
* Behavioral: logotherapy


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age 16-24 years HIV seropositive HIV disclosed Understand Thai language Parent signed written informed consent Exclusion Criteria: Mental or psychological disorder or having active suicidal idea or attempt Having no permanent address

Ages Eligible for Study
-----------------
Minimum Age: 16 Years
Maximum Age: 24 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Treatment arm (logotherapy)<br>Participants in Arm I will attend the logotherapy group sessions by the trained psychologist for 4 visits (see Table II, III). The number of participants in group sessions will be 20 participants per group. | Behavioral: logotherapy<br>* Logotherapy is therapy during which the interaction between the therapist and the client centres on the topic of meaning. The problems that the clients experience are presented to the client as inseparable parts of his everyday life. The client is then challenged to discover his/her meaning and to take responsibility in facing up to his/her problem. This approach is aimed at helping the client to deal and understand what his /her existences entail.<br>|
| No Intervention: Control arm (general health education)<br>Participants in Arm II will attend the routine health education by the nurse. The number of participants in group session will be 20 participants per group. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| PIL score | Change of PIL score at baseline and follow up visit between the two arms | week 48 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| QOL |  | 48 weeks | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
meaning of life, logotherapy, HIV-infected teenagers, adherence