A Retrospective Study of the Effects of Ocular Acupuncture on Ocular Motor Nerve Palsy

Study Overview
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Brief Summary
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This retrospective observational study is designed to assess the response to treatment with ocular acupuncture and its relative factors, in terms of diplopia status, ocular motility differences, and clinical features, in ocular motor nerve palsy patients. During this study, a retrospective data collection will be carried out using the information contained in the medical record of aimed patients, provided that the treatment with ocular acupuncture.

Official Title
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A Retrospective Study to Investigate the Efficacy and Relative Factors of Ocular Acupuncture in Ocular Motor Nerve Palsy Patients

Conditions
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Oculomotor Nerve Palsy, Trochlear Nerve Palsy, Abducens Nerve Paralysis

Intervention / Treatment
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* Other: Ocular acupuncture


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age over 18 years old Patient who received at lease 1 times of ocular acupuncture treatment Patient who received full set of ophthalmology & neurology assessment pre- and post-treatment. Exclusion Criteria: patient who combined with extraocular muscles diseases, eg.thyroid eye disease patient who underwent periocular surgery patient who combined with congenital ocular motor nerve palsy, eg. Brown syndrome. patient who had untreated condition which may lead to ocular motor nerve palsy such as intracranial aneurysm and brain tumor.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Ocular motor nerve palsy treated by ocular acupuncture<br>Ocular motor nerve palsy patients who received ocular acupuncture treatment | Other: Ocular acupuncture<br>* Patient's skin located in the extraocular muscles projection area is routinely disinfected. A diameter of 0.20 mm and length of 25 mm needle is inserted slowly. Piercing depth is about 20mm. The electropuncture apparatus is used, each group of electrodes are distinguished with different colors of wires to generate current stimulations of current 1.0 1.5 milliampere (mA), voltage 9 volt(V), frequency 1.5 hertz (Hz), and duration of 40 minutes.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Clinical efficacy rate (Cure, Effective and Invalid) | Clinical efficacy rate (Cure, Effective and Invalid) assessed by investigator's discretion. Efficacy rate is calculated as number of patients with Cure and effective proportional to number of all cases. | Through study completion, an average of 1 month. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Diplopia angle | Patient's diplopia angle obtained by retrospective chart review. | Through study completion, an average of 2 weeks. | 
| Eyeball movement distance | Patient's eyeball movement distance obtained by retrospective chart review. | Through study completion, an average of 2 weeks. | 
| Distance between upper and lower eyelid. | Patient's distance between upper and lower eyelid obtained by retrospective chart review. | Through study completion, an average of 2 weeks. | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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diplopia; ocular motor nerve palsy; acupuncture