Ultrasound Guided Costotransverse Block for Breast Cancer Surgery

Study Overview
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Brief Summary
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Costotransverse block is a novel regional anesthesia technique described a few months ago. It's use for breast surgery has been reported by only one case report in the literature. As the investigators have considered that Costotransverse block can be efficacious for providing postoperative analgesia in the breast surgeries, the investigators have implemented the application of this blockade into practice at the clinic. The main purpose of this study is to evaluate the analgesic effect of ultrasound-guided unilateral costotransverse block in breast cancer surgery.

Official Title
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Evaluation of Ultrasound Guided Costotransverse Block in Breast Canser Surgery Patients

Conditions
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Postoperative Pain

Intervention / Treatment
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* Other: costotransverse block


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients undergoing breast canser surgery under general anesthesia ASA I-II Exclusion Criteria: patients undergoing breast surgery under paravertebral block and others morbidly obesity ASA III - IV infection of the skin at the site of needle puncture area patients with known allergies to any of the study drugs coagulopathy recent use of analgesic/steroid drugs

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Costotransverse block<br>The Costotransverse block will be administrated to this group before induction of anesthesia. An intravenous patient-controlled analgesia device within morphine will be given to the patients postoperatively. | Other: costotransverse block<br>* patient controlled analgesia devices with tramadol<br>* Other names: patient controlled analgesia;|
| No Intervention: Control Group<br>In this group, patients will receive only multimodal analgesic treatment including patient-controlled analgesia with morphine. No block will be performed. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 24 hours morphine consumption | morphine consumptions for both group will be recorded | 24 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Numeric rating scale for postoperative pain intensity | Changes in Numeric Rating Scale (NRS) at rest and on movement will be recorded at intervals. NRS is a unidimensional measure of pain intensity in adults. The NRS is a segmented numeric version of the visual analog scale (VAS) in which a respondent selects a whole number (0-10 integers) that best reflects the intensity of his/her pain. The 11-point numeric scale ranges from '0' representing one pain extreme (e.g. no pain) to '10' representing the other pain extreme (e.g. pain as bad as you can imagine or worst pain imaginable). | 24 hours | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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ultrasound guided block