'WeChat WeQuit' Smoking Cessation Program

Study Overview
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Brief Summary
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This proposed project is to assess whether WeChat-based smoking cessation interventions ('WeChat WeQuit' program) will be effective at helping people in China who smoke, to quit.

Official Title
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The Efficacy of WeChat Based Interventions ('WeChat WeQuit' Program) for Smoking Cessation in China: a Randomized Trial

Conditions
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Cigarette Smoking, Smoking Cessation

Intervention / Treatment
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* Behavioral: Cognitive and Behavioral Intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Daily Chinese cigarette smokers. 18 years of age and older living. Being able to read and write in Chinese. Owning a smartphone and knowing how to use WeChat. Willing to make an attempt to quit smoking in the next month. Willing to provide informed consent to participate in the study. Exclusion Criteria: Nonsmokers. Smokers without attempt to quit. Below 18 years old. Unable to use smartphone and WeChat. Unable to read and write in Chinese.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Intervention Group<br>Participants in the intervention group will receive the 'WeChat WeQuit' program from the WeChat subscription account. The period for intervention was 14 weeks, including 2-week quiting preparation intervention and 12-week postquit intervention. The number of messages/pictures/audios received by participants will gradually decrease (will be intensively sent to them during 2-week prequit and 4-week postquit, and less intensively during 5-week to 12-week postquit), and follow-up questionnaires were sent only once a month in 14-28 weeks (week 16, 20, and 26 after the quit date). A WeChat group was created for answering questions from participants, and sharing the latest resources related to quitting smoking, and promoting communication between participants. | Behavioral: Cognitive and Behavioral Intervention<br>* Participants who allocate to the intervention group will receive regular smoking cessation related information by professional team.<br>|
| No Intervention: Control Group<br>Control group participants will not receive any smoking cessation messages by professional team. They will receive messages of thanking them for being in the study and reminding them of the time until their free month at the end of follow up. In order to measure the main two outcomes (self-reported continuous smoking abstinence and point prevalence of abstinence), continuous smoking abstinence, point prevalence of abstinence, how many cigarettes per day during the last week if they are still smoking will be checked at week 1, 4, 8, 12, 16, 20 and 26 points. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Biochemically Validated Continuously Abstinence | The primary outcome will be biochemical validation of self-reported 26-week continuous smoking abstinence | 26 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Self-reported 7-day Point Abstinence | Self-reported 7-day point-prevalence abstinence at week 1, 4, 8, 12, 16, 20 and 26 after quit date. | 26 weeks | 
| Self-reported Continuous Abstinence | Self-reported continuous smoking abstinence rate at weeks 4, 8, 12, 16, 20, and 26 after the quit date. | 26 weeks |