Infantile - Postoperative Residual Curarization - Study

Study Overview
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Brief Summary
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The primary object of this study is, to investigate the current procedure of neuromuscular monitoring at a tertiary academic university medical center.

Detailed Description
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Residual neuromuscular block is known to be a significant but frequently overlooked complication after the use of neuromuscular blocking agents. Aim of this prospective, observational study is to detect the incidence and severity of residual paralysis at a tertiary academic german university medical center. Methods: All infantile patients recieving neuromuscular blocking agents are included over a 12 week observational period. At the end of the operation procedure, directly prior to tracheal extubation a train-of-four ratio was assessed quantitatively by an independet observer using the TOF Watch SX monitor. Data related to patient postoperative outcome were collected in the operating theatre, during the way to the postoperative care unit (PACU) and during the stay in the PACU: incidence of residual paralysis incidence of aspiration, bronchospasm, laryngospasm, oxygen desaturation, airway obstruction,

Official Title
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Observational Study to Detect Postoperative Residual Curarization in Infantile Patients

Conditions
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Postoperative Residual Curarization, Neuromuscular Blockade, Neuromuscular Monitoring

Intervention / Treatment
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* Diagnostic Test: Acceleromyography


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: General aneasthesia with muscle relaxation Children between 1 Month to 18 Years Endotracheal Intubation due to surgical or diagnostical procedures Exclusion Criteria: older than 18 years local aneasthesia regional aneasthesia larynx mask patient comes from ICU children who are not planned to be extubated

Ages Eligible for Study
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Minimum Age: 1 Month
Maximum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: Acceleromyography|At the End of Surgery, shortly before Extubation, the TOF-Ratio is measured by an independent investigator using Acceleromyography.|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Residual paralysis | Rate of residual paralysis after extubation of the infantile patients measured by acceleromyography. | Directly prior to extubation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Airway obstruction | Clinical assessment of the upper airway | 1, 10, 30, 60 minutes after extubation | 
| Oxygen desaturation | Measurement of the oxygen saturation by pulse oxymetry | 1, 10, 30, 60 minutes after extubation | 
| Bronchospasm, laryngospasm | Clinical assessment the airway | 1, 10, 30, 60 minutes after extubation |