A Different Use of The Aerosol Box in COVID-19 Patients; Internal Jugular Vein Cannulation

Study Overview
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Brief Summary
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During the COVID-19 pandemic, health employees are at high risk of infection. This study aimed to determine experiences with an aerosol box (AB), used with the aim of preventing contamination by droplets during internal jugular vein cannulation which requires close contact with COVID-19 patients, and the necessity to use this device.

Detailed Description
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The study included 40 patients with diagnosis of COVID-19 requiring central venous catheter during treatment in the ward. The patients were randomly allocated to one of the two protective equipment groups and, then, randomly assigned to one of the five clinicians. Group P&A had both personal protective equipment (PPE) and AB used, while Group P included patients where PPE was used alone. Clinicians completed a survey after performing the procedure to evaluate the use of the aerosol box. Collected data of the procedures and patients, were analyzed. In addition, survey data were evaluated.

Official Title
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Use of Aerosol Box for Ultrasound-guided Internal Jugular Vein Cannulation in COVID-19 Patients; Single Center Experience

Conditions
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COVID-19 Pneumonia

Intervention / Treatment
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* Procedure: Internal jugular vein cannulation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients diagnosed with COVID-19 and inserted central venous catheter while being treated in the ward Exclusion Criteria: Patients under the age of 18 years Patients who can not lie in the supine position due to severe respiratory distress, Patients with thrombus in the right İJV in evaluation with US

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Group P<br>The clinicians performed an internal jugular vein cannulation using only personal protective equipment. | Procedure: Internal jugular vein cannulation<br>* The clinicians performed an internal jugular vein cannulation using personal protective equipment (PPE) or both of the aerosol box and PPE provide insertion of a central venous catheter in COVID-19 patients.<br>|
| Active Comparator: Group P&A<br>The clinicians performed an internal jugular vein cannulation using personal protective equipment and aerosol box. | Procedure: Internal jugular vein cannulation<br>* The clinicians performed an internal jugular vein cannulation using personal protective equipment (PPE) or both of the aerosol box and PPE provide insertion of a central venous catheter in COVID-19 patients.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Questionnaire on the Use of Aerosol Boxes | There is no valid and reliable questionnaire in the literature that evaluates behaviors and attitudes towards aerosol box use. Therefore, in our study, a questionnaire was conducted about the attitudes and behaviors of the participants towards aerosol box preservatives.There are 6 statements in the content of the questionnaire on aerosol box use. The questionnaire consists of expressions such as 1-Discomfort using box, 2-Difficulty in manipulation during the performance, 3-Difficulty in use of US device restricted by box, 4-Increased cognitive load from use of box, 5-Increased physical load from use of box, 6-User satisfaction respectively. Participants were asked to answer these statements as ''yes or no''. According to the response received, positive or negative attitudes towards the use of aerosol boxes were evaluated. | 7 months from the index case of the pandemic in Turkey | 
| Catheter-related infection after central venouse catheterization in COVID-19 | When the body temperature of the patients is above 38, blood, urine and if the patient is intubated, a tracheal aspirate culture will be taken. If the blood culture test is a positive, a diagnosis of catheter-related infection will be made and central venouse catheter will be removed. | 7 months from the index case of the pandemic in Turkey | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of arterial punctures | The difference in the number of arterial punctures developed during central venous catheterization in patients with or without aerosol box. | 7 months from the index case of the pandemic in Turkey | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Aerosol box, SARS-CoV-2 virus, COVID-19, Internal jugular vein, Personal protective equipment