Prevalence of H. Pylori Gastritis in Sleeve Gastrectomy Specimens

Study Overview
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Brief Summary
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This is a cross-sectional study looking for prevalence of H.Pylori related gastritis among patients underwent sleeve gastrectomy over five year study period. The study also looks for possible association with patients's characteristics. Also, compares its findings with similar regional and international studies.

Official Title
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Prevalence of H. Pylori Gastritis in Sleeve Gastrectomy Specimens: A Cross-Sectional

Conditions
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Gastritis H Pylori, Gastritis, Obesity Associated Disorder

Intervention / Treatment
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* Other: Giemsa stain


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients who underwent sleeve gastrectomy surgery was performed between January 2015 and October 2019 Exclusion Criteria: patients whose resected specimens were not examined histopathologically

Ages Eligible for Study
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Minimum Age: 12 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients with Gastritis<br>Patients who underwent sleeve gastrectomy and the histopathology result of resected gastric specimen showed the presence of gastritis in it. | Other: Giemsa stain<br>* Giemsa special stain was employed for detection of H. Pylori microorganisms.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prevalence of gastritis | proportion of patients who underwent sleeve gastrectomy who have gastritis in their resected gastric specimen at or during study period. calculated as (number of pt with gastritis / number of examined resected gastric specimens) | start to end of the study, 5 years | 
| Prevalence of H.pylori gastritis | proportion of patients who underwent sleeve gastrectomy who have H.pylori related gastritis in their resected gastric specimen at or during study period. calculated as (number of pt with H.pylori gastritis / number of examined resected gastric specimens) | start to end of the study, 5 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prevalence of other histopathological findings | proportion of patients who underwent sleeve gastrectomy who have histopathological findings not including gastritis or H.pylori related gastritis in their resected gastric specimen at or during study period. calculated as (number of pt with the histopathological finding / number of examined resected gastric specimens) | start to end of the study, 5 years | 
| likelihood ratio between H.pylori gastritis and advancing age | The relationship between H.pylori gastritis and advancing age. likelihood ratio will be calculated by cross table analysis using Statistical Analysis Software SPSS program version 26. | start to end of the study, 5 years | 
| likelihood ratio between H.pylori gastritis and female gender | The relationship between H.pylori gastritis and female gender. likelihood ratio will be calculated by cross table analysis using Statistical Analysis Software SPSS program version 26. | start to end of the study, 5 years | 
| likelihood ratio between H.pylori gastritis and BMI | The relationship between H.pylori gastritis and body mass index (BMI). weight and height will be combined to report BMI in kg/m^2 likelihood ratio will be calculated by cross table analysis looking for using Statistical Analysis Software SPSS program version 26. | start to end of the study, 5 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Sleeve gastrectomy, LSG, Gastritis, H. Pylori, Jordan, Middle East, Histopathology