Characterization of the Pattern of Consumption and Withdrawal Syndrome From Dual Cannabis and Tobacco Use

Study Overview
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Brief Summary
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Aims: To characterize the pattern of cannabis and tobacco use and withdrawal symptoms in people who start treatment for cannabis use disorders (exclusive cannabis, concurrent and/or simultaneous with various tobacco products) through an aplication game and considering the type of users. Methodology: Mixed-methods research composed of three studies. Study I: qualitative participatory action study aimed at exploring the experiences and preferences of the cannabis users on the use of apps. This information will be instrumental in the co-design of the app. Study II: prospective longitudinal study aimed to establish consumption patterns and transitions between substances and to validate the scale of cannabis withdrawal symptoms in the Spanish population. Sample size: expected RR=1.20, α =0.05, β= 0.20, losses= 20% (n=282). Study III: qualitative study to explore participants' experiences during the process of quitting cannabis and / or tobacco. Expected results: Characterization and prediction of variables that influence cannabis and tobacco cessation/ reduction and describe withdrawal symptoms according to consumption patterns with aim of improving the design of future interventions.

Official Title
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Characterization of the Pattern of Consumption and Withdrawal Syndrome From Dual Cannabis and Tobacco Use in People With Cannabis Use Disorder Who Initiate Dishabituation Treatment (DuCATA_GAM-CAT)

Conditions
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Cannabis Dependence, Tobacco Use, Withdrawal Syndrome, Substance Abuse

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Smokers (at least 1cig./week) Undertreatment for Cannabis >=18 years-old Under clinical follow-up Informed consent Have a Smartphone Exclusion Criteria: Severe cognitive impairment 3-month follow-up not guaranteed

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cannabis use | Number of participants that use several cannabis products (hashish, marijuana, etc.) | Change between baseline and 6 weeks follow-up | 
| Tobacco use | Number of participants that use several type of tobacco product/s | Change between baseline and 6 weeks follow-up | 
| Abstinence from cannabis | If a participant reduces or quits their cannabis use, we will ask for their presence of 16 withdrawal symptoms. Each symptom is scored from 0 (minimum) to 3 (maximum). Higher scores mean a worse outcome. | Change between baseline and 6 weeks follow-up | 
| Abstinence from tobacco | If a participant reduces or quits their tobacco use, we will ask for their presence of 6 withdrawal symptoms using the Fagerström test. The test has a minimum score of 0 and a maximum of 10. Higher scores mean a worse outcome. | Change between baseline and 6 weeks follow-up | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Motivation to quit | Using a Likert scale randing from 0 to 10 (0=totally unmotivated and 10= totally motivated) | Baseline | 
| Psychological assessment | States of change or readiness to quit cannabis and tobacco according to Prochaska and Di Clemente's model (pre-contemplative, contemplative, prepared, action and maintenance. | Baseline | 
| Self-perceived health status | Will be assessed based on How would you say your general health is? (excellent, very good, good, fair, very fair, poor) | Baseline | 
| Social and cultural factors | Questions related to their social circle/network (friends and colleagues) and social climate overall | Baseline | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Cannabis, Tobacco, Treatment, Social network