Patients With Behavioural Symptoms and Hospitalized in Cognitive and Behavioural Units

Study Overview
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Brief Summary
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Cognitive and behavioral units (CBUs) have been created between 2008 and 2012 French National Alzheimer plan for the management of behavior problems of patients suffering from Alzheimer's disease or other related disorders and necessitating hospitalisation. This Alzheimer plan is promoting the evaluation of these units through the observation of the behavioral and psychological symptoms of dementia (BPSD) evolution. As these units are new, it appears important to assess their long-term impact on patients care.

Detailed Description
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EXPECTED RESULTS The present study should allow to better understand the long-term impact of CBU on care of patients with Alzheimer disease and BPSD. Moreover, it should allow to identify patients improved by CBU.

Official Title
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Initial and Long-term Evaluation of Patients With Behavioural Symptoms and Hospitalized in Cognitive and Behavioural Units

Conditions
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Alzheimer Disease

Intervention / Treatment
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* Behavioral: patients with alzheimer's disease


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patient hospitalized on CBUs patient with the diagnostic criteria for disease related to dementia stage with a Clinical Demential Rating ≥ 1 patient with a caregiver who is fairly frequent contact with the patient in order to observe the appearance of behavior changes Exclusion Criteria: Patient living alone at home Patient with risk of death within one year

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| patient with alzheimer's disease<br>Cohort of patients with psychological symptoms of dementia hospitalised in Cognitive and Behaviorial Units (CBUs) Evaluation of these units through the observation of the behavioral and psychological symptoms of dementia evolution : NPI score, caregivers quality of life, caregivers burden, collection of psychotropic drugs, the rehospitalisation rate | Behavioral: patients with alzheimer's disease<br>* the Neuropsychiatric Inventory (NPI), is uded to assess 10 behavioral disturbances occurring in dementia patients: delusions, hallucinations, dysphoria, anxiety, agitation/aggression, euphoria, disinhibition, irritability/lability, apathy, and aberrant motor activity. The NPI uses a screening strategy to minimize administration time, examining and scoring only those behavioral domains with positive responses to screening questions.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Neuropsychiatric Inventory (NPI) score | impact of CBU effectiveness in reducing BPSD | one year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| CBU effectiveness in reducing BPSD |  | 6 months | 
| CBU effectiveness on quality of life of patients and caregivers, and on caregivers' burden |  | one year | 
| Psychotropic drugs (in particular neuroleptic drugs) consumption |  | one year | 
| rehospitalisation rate for BPSD of the patients in the year following their hospitalisation in CBU |  | one year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Cognitive and behavioral units, Alzheimer Disease, Dementia