23-gauge Pars Plana Vitrectomy With Silicone Oil Injectionsilicone Oil Injection With Surgical

Study Overview
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Brief Summary
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Objective: to evaluate anatomical and visual outcomes of 23-gauge vitrectomy for retinal detachment with silicone oil injection in fifty cases. The rate of recurrence, the incidence of proliferative vitreoretinopathy (PVR) and the value of risk factors. Participants and Methods: fifty cases with RD with mixture of epiretinal and subretinal membranes were collected. Pars plan vitrectomy, 23gauge vitrectomy were done to these cases, then silicone oil removed 6 weeks after primary surgery. Main Outcome Measures: The anatomical success rate,the failure rate ,the rate of retinal breaks in both groups, and reproliferation rate.

Detailed Description
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50 Patients were included if they had retinal detachment, moderate degrees of PVR, PVR ≥ Grade C, previous buckle surgery and pseudophakia. A good and correct assessment of the detached retina was done. Investigator followed the Lincoff rules to find the retinal breaks. Investigator performed a three-port vitrectomy: one infusion trocar and two instruments trocars. Non-contact wide-angle viewing systems (Resight- Biom) have a viewing field of 60-130° was used. Investigator used Perfluorocarbon liquid (PFCL) for attaching the retina with its gravity. Then performing PFCL against air exchange.The retina will be attached under air tamponade. Laser photocoagulation was performed in the air-filled eye. Investigator applied the laser effects confluently surrounding all retinal breaks. Then silicone oil (1000 centistokes) was injected as a final step and permanent tamponade.After 3-6 months investigator removed the silicone and examined the retina for 6 weeks after surgery to detect the recurrent cases.

Official Title
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Surgical Techniques for Epiretinal Membrane Removal in Pars Plana Vitrectomy: A Comparative Study Between 20-Gauge and 23-Gauge Vitrectomy

Conditions
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Retinal Detachment

Intervention / Treatment
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* Procedure: 23 PARS PLANA VITRECTOMY


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: they had retinal detachment, moderate degrees of PVR PVR ≥ Grade C previous buckle surgery pseudophakia. Exclusion Criteria: the retinal tear was greater than 90 degrees presence of intravitreal foreign body previous vitrectomy done before if follow-up data were unavailable for a minimum follow-up of 6 months following the final retinal procedure.

Ages Eligible for Study
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Minimum Age: 23 Years
Maximum Age: 58 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Fifty participants were assigned and divided into two groups. Participants without RD after SO removal was recruited into group A-NRD, and participants with RD after SO removal was recruited into group B-RD.
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Sham Comparator: Non retinal detachment group<br>35 participants did 23 vitrectomy followed for 3-6 months. After that, we removed the oil and followed them for 6 weeks. | Procedure: 23 PARS PLANA VITRECTOMY<br>* We performed a three-port vitrectomy: one infusion trocar and two instruments trocars. Non-contact wide-angle viewing systems (Resight- Biom) have a viewing field of 60-130° was used. Put 23 needle attached to the automated pump for silicone oil extraction. Strict examination of the retina to detect new breaks or untreated breaks. Closure of the sclerotomies.<br>* Other names: SILICONE OIL REMOVAL;|
| Active Comparator: retinal detachment group<br>15 participants did 23 vitrectomy followed for 3-6 months. After that, we removed the oil and followed them for 6 weeks. | Procedure: 23 PARS PLANA VITRECTOMY<br>* We performed a three-port vitrectomy: one infusion trocar and two instruments trocars. Non-contact wide-angle viewing systems (Resight- Biom) have a viewing field of 60-130° was used. Put 23 needle attached to the automated pump for silicone oil extraction. Strict examination of the retina to detect new breaks or untreated breaks. Closure of the sclerotomies.<br>* Other names: SILICONE OIL REMOVAL;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| success rate | success rate after first RD surgery and silicone oil removal | 42 days | 
| The failure rate | The failure rate after silicone oil removal | 42 days | 
| number of surgical interference | numbers of vitrectomies done after silicone oil removal | 4 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| lower retinal breaks | The rate of lower retinal breaks in RD group versus the rate of lower retinal breaks in NRD group was | 4 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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retina, silicone, laser, break, vitrectomy