Laser Resurfacing Versus Dermabrasion for Scar Revision

Study Overview
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Brief Summary
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Dermabrasion has been the historical standard used for resurfacing scars on the skin. Recently, fractionated laser therapy has been FDA approved for scar resurfacing. This study intends to compare dermabrasion versus fractionated laser therapy for scar resurfacing.

Official Title
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A Comparison Evaluation of Fractional Laser Therapy and Dermabrasion for Scar Revision

Conditions
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Cicatrix, Dermabrasion, Coagulation, Laser

Intervention / Treatment
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* Device: Fractionated laser
* Device: Dermabrasion


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Post-surgical or post traumatic scar on face or scalp. Age 18 or older Able to read and comprehend English Willing to follow treatment schedule and post treatment care requirements Signed the informed consent form Fitzpatrick skin type I-III Exclusion Criteria: known photosensitivity Taken any medications known to induce photosensitivity in previous three months Taken Accutane within past 12 months Pregnant or nursing Currently on topical or oral antibiotics Immunocompromised status Skin type IV or greater

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Fractionated laser<br>This Arm is the section of scar that will be treated with Fractionated Laser | Device: Fractionated laser<br>* Fractionated laser in the form of the Re:Pair CO2 laser manufactured by Solta Medical.<br>|
| Active Comparator: Dermabrasion<br>Dermabrasion is the gold standard for scar resurfacing and will be used as the control against which Fractionated Laser is compared. | Device: Dermabrasion<br>* Diamond Fraise Dermabrasion will be performed in standard fashion down to papillary dermis.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Safey Data Score Based on Ordinal Ratings of Erythema, Edema, Bleeding, Eschar After Resurfacing | Erythema, edema, bleeding, and eschar after resurfacing were used as indicators of safety. Each was judged based on a 4 point ordinal scale 0=absent, 1=mild, 2=moderate, 3=severe. | Day 0, Week1, Month 1 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual Analog Scale for Assessing Scar Improvement. | Visual Analog Scale for assessing scar improvement. 0 : Worsening or no improvement : 1-25% improvement : 26-50% improvement : 51-75% improvement : 76-100% improvement | 3 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Cicatrix, Dermabrasion, Coagulation, Laser