Intermittent Compression Maneuver of Upper Arm to Reduce Axillary Brachial Plexus Block Onset Time

Study Overview
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Brief Summary
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This study evaluates the addition of intermittent pneumatic compression maneuver to axillary brachial plexus block in forearm and hand surgery. Half of participants will receive axillary brachial plexus block and intermittent pneumatic compression maneuver, while the other half will receive only axillary brachial plexus block.

Official Title
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Intermittent Pneumatic Compression May Reduce Brachial Plexus Block Onset Time

Conditions
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Forearm Injuries, Hand Injuries

Intervention / Treatment
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* Procedure: Ultrasound guided axillary plexus block
* Procedure: Intermittent pneumatic compression maneuver


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: adults between ages of 20 and 50 patients who are scheduled forearm and hand surgery with axillary brachial plexus block American Society of Anesthesiologists Physical Status classification 1 or 2 patients who voluntarily agree to participate in the trial Exclusion Criteria: patients who are pregnant or lactating patient who does not agree to participate in the study patient with side effects on local anesthetics patient with neurologic deficit of upper arm patients with comorbidities of cardiac, pulmonary, renal, cerebral, and hepatic systems patients with peripheral vascular disease

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Brachial plexus block with intermittent pneumatic compression<br>Hand and forearm surgery is performed after axillary brachial plexus block with intermittent pneumatic compression for 3 minutes. | Procedure: Ultrasound guided axillary plexus block<br>* Ultrasound guided axillary plexus block with 1.5% mepivacaine 30 ml<br>Procedure: Intermittent pneumatic compression maneuver<br>* Following ultrasound guided axillary plexus block, the pneumatic compression maneuver of upper arm is composed of 6 repeated inflation-deflation periods; inflation with a pressure of 200 mmHg for 30 seconds and deflation for 10 seconds each.<br>|
| Placebo Comparator: Brachial plexus block<br>Hand and forearm surgery is performed after axillary brachial plexus block only. | Procedure: Ultrasound guided axillary plexus block<br>* Ultrasound guided axillary plexus block with 1.5% mepivacaine 30 ml<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Time to achieve complete sensory block | Defined as the time to reach an absent sensation in the pinprick test at all four nerve distributions (ulnar nerve, radial nerve, median nerve, and musculocutaneous nerve) | 1 hour | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Time to achieve surgical anaesthesia | Defined as the time to reach an absent sensation in the pinprick test and reduced power at all four nerve distributions (ulnar nerve, radial nerve, median nerve, and musculocutaneous nerve) | 1 hour | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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brachial plexus block, intermittent pneumatic compression maneuver