Interactive Voice Response Technology to Mobilize Contingency Management for Smoking Cessation

Study Overview
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Brief Summary
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Cigarette smoking remains the most common source of preventable morbidity and mortality in the United States, with in excess of $167 billion in economic costs per year. Contingency management (CM), in which tangible incentives are provided contingent on a target behavior like abstinence, is highly efficacious in improving substance abuse treatment outcomes and is receiving increased attention for smoking cessation. Expired carbon monoxide (CO) is the most common objective smoking status test used in smoking research and treatment. Unfortunately, multiple CO tests/day are typically required to detect all smoking and reinforce sustained abstinence. The resulting logistical and resource limitations greatly limit the application of this potentially powerful quit smoking toolset. This study addresses these limitations by examining the effectiveness of using interactive voice response technology (IVR) to implement CM. Smokers who want to quit (N = 90 randomized) will receive 2 quit preparation sessions based on public health guidelines for smoking cessation and set a target quit date. Participants will be randomly assigned to 1 of 2 treatment conditions: (a) IVR-S consisting of objective smoking status monitoring using IVR, telephone counseling and transdermal nicotine and (b) IVR-CM, consisting of the same monitoring, telephone counseling and transdermal nicotine plus IVR-based CM for smoking abstinence. It is hypothesized that abstinence rates will be higher in the IVR-CM condition compared to the IVR-S, supporting a combined IVR CM approach, and thereby greatly increasing the applicability of these powerful smoking cessation tools.

Official Title
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Interactive Voice Response Technology to Mobilize Contingency Management for Smoking Cessation

Conditions
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Cigarette Smoking

Intervention / Treatment
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* Behavioral: contingency management for smoking abstinence
* Drug: transdermal nicotine
* Behavioral: Telephone counseling


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: regular cigarette smoker age ≥ 18 mailing address & valid photo I.D. want transdermal nicotine Exclusion Criteria: not English speaking in recovery for pathological gambling contraindication for transdermal nicotine female who is pregnant, nursing a child, or not using effective contraception

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Standard Care<br>Telephone counseling plus nicotine patch | Drug: transdermal nicotine<br>* Participants receive an 8 week supply of transdermal nicotine [21 mg patches (4 wks), 14 mg (2 wks), 7 mg (2 wks)].<br>Behavioral: Telephone counseling<br>* Participants receive brief twice weekly telephone counseling.<br>|
| Experimental: Contingency management for abstinence from cigarettes<br>Telephone counseling and nicotine patch plus contingency management | Behavioral: contingency management for smoking abstinence<br>* Participants earn the chance to win prizes for breath samples that test negative for cigarette smoking.<br>Drug: transdermal nicotine<br>* Participants receive an 8 week supply of transdermal nicotine [21 mg patches (4 wks), 14 mg (2 wks), 7 mg (2 wks)].<br>Behavioral: Telephone counseling<br>* Participants receive brief twice weekly telephone counseling.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Longest duration of abstinence |  | Week 24 |