The Effect of Probiotic Supported Yogurt Consumption on Gastrointestinal Symptoms

Study Overview
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Brief Summary
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Probiotics have beneficial effect on Gastrointestinal Symptoms. The aim of this study is to determine the effect of probiotic yogurt consumptions on the people who have gastrointestinal symptoms mainly constipation.

Detailed Description
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In the beginning of the study Constipation Severity Scale and Bristol Stool Scale was applied to the all people who accepted to participate in this study. According to the student T test analysis (α= 0.05, β=0.20 ) 102 people with gastrointestinal symtoms should be included in the study. When 102 people are found with gastrointestinal symptoms second stage of the study will begin. In this stage of the study 102 people are randomly divided into 2 homogeneous groups. 3 day food record will be taken from 102 people at the beginning and again at the end of the study. Probiotic yogurt (Activia Probiotic Yogurt without any aroma-125 g) will be given to one group for 1 month and nothing will be given to the other group (control group).

Official Title
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The Effect of Probiotic Supported Yogurt Consumption on Gastrointestinal Symptoms Among People Aged 19-64 Years

Conditions
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Gastrointestinal Dysfunction

Intervention / Treatment
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* Dietary Supplement: Activia Probiotic Yogurt


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Living in Izmir Individuals who are having BMI between 18.5-24.9 kg / m2 Having gastrointestinal symptoms according to Constipation Severity Scale and Bristol Stool Scale Exclusion Criteria: Having diagnosed gastrointestinal disease Regular consumption of probiotic Using of drug that affects gastrointestinal system Presence of mental illness

Ages Eligible for Study
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Minimum Age: 19 Years
Maximum Age: 64 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: Control Group<br>This group will be just follow-up for 4 weeks without any intervention | |
| Experimental: Interventional Group<br>This group will consume 125 g plain Activia Probiotic Yogurt without any aroma/fruit during 4 weeks/1 month | Dietary Supplement: Activia Probiotic Yogurt<br>* Activia probiotic Yogurt will be consumed by participants in this group<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The severity of gastrointestinal symptoms (mainly constipation) will decrease in the interventional group | We expect to see improvement in the gastrointestinal symptoms after consuming probiotic yogurt | 4 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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probiotic, gastrointestinal symptoms, constipation