Gingival Recession Treatment Using Two Different Surgical Techniques

Study Overview
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Brief Summary
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Coronally the advanced flap is considered a predictable treatment of gingival recession but in certain situations, it needs a filler like subperiosteal connective tissue graft (CTG) which is considered as the gold standard treatment approach. This randomized controlled trial compares the clinical benefits and effectiveness of a xenogenic collagen matrix (mucoderm, botiss, dental, Berlin, Germany) as a filler to the subperiosteal connective tissue graft (CTG).

Official Title
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Root Coverage Using Tunneling Technique of Xenogenic Collagen Matrix vs. Autologous Connective Tissue as a Treatment of Miller Class Two Gingival Recession (RCT Study)

Conditions
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Gingival Recession, Root Planing

Intervention / Treatment
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* Procedure: xenogeneic collagen matrix


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: -The selected patients for this study are non-smokers, aged 18-60 years with multiple gingival recession (Miller class 1, or 2.) for more than two adjacent affected teeth with plaque score less than 25% Exclusion Criteria: -Patients with systemic complications, psychological problems, parafunctional habits, or patients presented with Mal-posed teeth, hypermobile teeth, teeth with Miller class 3 gingival recession were excluded from this study.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: root coverage surgeries using autologous connective tissue for treatment of gingival recession<br>root coverage surgeries using tunneling technique of autologous connective tissue as a treatment of Miller class two gingival recession | Procedure: xenogeneic collagen matrix<br>* xenogeneic collagen matrix called mucoderm used for root coverage for treatment of gingival recession instead of harvesting from the patients connective tissue<br>|
| Experimental: root coverage surgeries using xenogenic collagen matrix for treatment of gingival recession<br>root coverage surgeries using tunneling technique of mucodrm membrane ; xenogeneic collagen matrix as a treatment of Miller class two gingival recession | Procedure: xenogeneic collagen matrix<br>* xenogeneic collagen matrix called mucoderm used for root coverage for treatment of gingival recession instead of harvesting from the patients connective tissue<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The zone of keratinized gingiva | The distance from the tip of the papilla to the mucogingival junction minus the probing depth measured in mm using graduated periodontal probe. | 6 months after the surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Periodontal probing depth | measured from the gingival margin to the depth of the gingival sulcus in six sites per tooth and measured in mm. | 6 months after the surgery | 
| Clinical attachment loss | measured from the cementoenamel junction to the depth of the sulcus in six sites per tooth and measured in mm. | 6 months after the surgery | 
| Gingival recession | The depth measured from the gingival margin to the cementoenamel junction in mm. | 6 months after the surgery | 
| Patient satisfaction of the esthetics | measured using the visual analog scale. | 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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root coverage, mucoderm, connective tissue, grafts