Efficacy of Diode Laser in Peri-implantitis

Study Overview
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Brief Summary
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The aim of this study was to compare the efficacy of a diode laser (DL) as an adjunct to conventional scaling in the treatment of mild-to-moderate peri-implantitis. A prospective clinical, radiographic and microbiologic split-mouth study was conducted to test the following null hypothesis; adjunct application of a diode laser, in the conventional treatment of peri-implantitis, are not associated with a statistically significant difference regarding the microbial counts, marginal bone loss and peri-implant parameters.

Detailed Description
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Efficacy of a diode laser (DL) in peri-implantitis was investigated. 48 implants diagnosed with peri-implantitis were included. In addition to the conventional scaling and debridement, random 24 implants were lased by a DL. Periodontal indexes, microbiologic specimens and radiographs were used for assessment. Baseline parameters were similar between groups. After six months laser group revealed higher MBL than the control group. Microbiota of the implants were found unchanged after one month. DL appears to have no additional positive influence on the peri-implantitis treatment.

Official Title
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A Randomized Clinical Trial of an Adjunct Diode Laser Application in the Treatment of Peri-implantitis.

Conditions
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Implant, Peri-Implantitis, Alveolar Bone Loss, Complications

Intervention / Treatment
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* Procedure: Conventional peri-implantitis treatment
* Device: DL application in peri-implantitis


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 18 years and older No local and systemic health problems prohibit the study interventions Bi-lateral implants with peri-implantitis diagnosis Exclusion Criteria: Local and systemic health problems prohibiting the study interventions

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Conventional peri-implantitis treatment<br>Peri-implantitis treatment according to the Cumulative interceptive supportive (CIST) therapy. | Procedure: Conventional peri-implantitis treatment<br>* Elimination of the bacterial plaque. Establishing optimal healing conditions. Detoxification of the affected environment.<br>* Other names: CIST treatment protocol;|
| Experimental: DL application in peri-implantitis<br>Adjunct Diode Laser application. | Device: DL application in peri-implantitis<br>* Diode laser application in the diseased implants.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bacterial counts | Bacterial load around the the diseased implants will be determined at the initiation of the study. The assessment will be performed after one months | One month | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Marginal Bone loss | The marginal bone loss around the diseased implants will be assessed after six months to analyse any bone level change. | Six months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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dental implant, laser, diode laser, peri-implantitis, bacterial count