Short Term Effects of Increasing Sleep Duration

Study Overview
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Brief Summary
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A series of studies are proposed to develop an intervention to increase sleep duration and study the effects on eating, exercise, and weight control. The hypothesis is that increasing sleep duration will help improve weight loss and maintenance.

Detailed Description
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Study 1 is conducted in a sleep laboratory. Participants sleep short duration (approximately four hours per night) on one weekend and long duration (approximately nine hours per night) on another weekend. Study 2 is examining ways to increase sleep duration in overweight individuals with short sleep and examining the effects on short term weight loss. Study 3 is comparing a standard weight loss program with a novel Sleep+Weight Loss intervention.

Official Title
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Increasing Sleep Duration: A Novel Approach to Weight Control

Conditions
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Overweight and Obesity

Intervention / Treatment
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* Behavioral: Sleep Duration
* Behavioral: No change in sleep


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: age 25 to 45; BMI 25 to 50; healthy; sleep 6.5 hours or less per night Exclusion Criteria: use of sleep medications; sleep apnea; third shift worker

Ages Eligible for Study
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Minimum Age: 25 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Increase Sleep Gradually<br>Subjects in this condition are taught to increase their sleep by 30 minutes per night during week 1 of the intervention; 60 minutes during week 2; and 90 minutes during week 3. Following the sleep intervention, these participants receive a standard behavioral with loss intervention. | Behavioral: Sleep Duration<br>* Subjects are taught sleep hygiene strategies to increase their sleep; they record their sleep in a diary and wear an actigraph and call in their sleep to the office each day.<br>|
| Active Comparator: Increase Sleep Immediately<br>Subjects in this condition are taught to increase their sleep by 90 minutes per night starting in week 1. Following the sleep intervention, these participants receive a standard behavioral with loss intervention. | Behavioral: Sleep Duration<br>* Subjects are taught sleep hygiene strategies to increase their sleep; they record their sleep in a diary and wear an actigraph and call in their sleep to the office each day.<br>|
| Active Comparator: No Intervention: Control Group<br>This group is told to make no changes in their sleep habits. Following the sleep intervention, these participants receive a standard behavioral with loss intervention. | Behavioral: No change in sleep<br>* This group is taught to maintain their current sleep habits.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Sleep Duration | Participants with verified short sleep are taught to increase their sleep either gradually or immediately. These two groups are compared to a control group who makes no changes in their sleep. The primary outcome is sleep duration per night as determined by actigraphy. | 4 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Eating Behavior | 24-hour recalls are used to estimate dietary intake at baseline and after 4 weeks of sleep intervention. | 4 weeks | 
| Physical Activity | Objective measures of physical activity are obtained before and after the 4-week sleep intervention. | 4 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Weight loss, Sleep duration