Fatty Liver Response of Cardio-metabolic Risk Factors to Laser Acupuncture Versus Cupping

Study Overview
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Brief Summary
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Every-two-week applied cupping (with scarification) session within one month on back of upper thorax is not compared previously regarding its effect on cardio-metabolic risk factors to the daily application of laser on acupoints (for month, except Fridays) in fatty liver patients. This trial will compare the two procedure effects on cardio-metabolic risk factors in fatty liver.

Detailed Description
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In fatty liver patients,every-two-week applied cupping (with scarification) session within one month on back of upper thorax for 30 patients will be compared regarding its effect on cardio-metabolic risk factors to the daily application of laser on acupoints (for month, except Fridays) of other 30 patients.

Official Title
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Non-alcoholic Fatty Liver Response of Cardio-metabolic Risk Factors to Laser Acupuncture Versus Cupping-with-scarification

Conditions
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Fatty Liver

Intervention / Treatment
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* Device: laser stimulation for acupoints
* Other: cupping with scarification


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Diagnosed Fatty liver patients by ultrasonography Class I obese patients Exclusion Criteria: Cardiovascular and respiratory disorders/diseases. Autoimmune disorders/diseases. Pregnancy Other liver disorders/diseases.

Ages Eligible for Study
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Minimum Age: 35 Years
Maximum Age: 55 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: laser<br>In fatty liver patients (30 patients), a daily application of 4-minute laser (for one month, except Fridays) on acupoint number 25,40,36 of stomach meridian, acupoint number 3 of liver meridian, acupoint number 6 of spleen meridian,acupoint number 9.12,4 of conception vessel meridian, acupoint number 14 of governor vessel meridian, acupoint number 4, 11 of large intestine meridian, acupoint number 34 of gall bladder meridian | Device: laser stimulation for acupoints<br>* In fatty liver patients (30 patients), a daily application of 4-minute laser (for one month, except Fridays) on acupoint number 25,40,36 of stomach meridian, acupoint number 3 of liver meridian, acupoint number 6 of spleen meridian,acupoint number 9,12,4 of conception vessel meridian, acupoint number 14 of governor vessel meridian, acupoint number 4, 11 of large intestine meridian, acupoint number 34 of gall bladder meridian<br>|
| Experimental: cupping with scarification<br>In fatty liver patients (30 patients),every-two-week applied cupping (with scarification) session within one month on back of upper thorax | Other: cupping with scarification<br>* In fatty liver patients (30 patients),every-two-week applied cupping (with scarification) session within one month on back of upper thorax<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| high-density lipoprotein | serum lipid | It will be measured after 4 weeks of treatment | 
| low-density lipoprotein | serum lipid | It will be measured after 4 weeks of treatment | 
| cholesterol | serum lipid | It will be measured after 4 weeks of treatment | 
| triglyceride | serum lipid | It will be measured after 4 weeks of treatment | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| c reactive protein | it will be measured in plasma | It will be measured after 4 weeks of treatment | 
| blood glucose | fasting gluocse | It will be measured after 4 weeks of treatment | 
| blood pressure | it will be measure with manual manometer | It will be measured after 4 weeks of treatment | 
| rate of pulse | it will be measured at radial artery | It will be measured after 4 weeks of treatment |