Comparison Between Gastric and Post Pyloric Tube Feedings in Children With Bronchiolitis Requiring High Flow Nasal Cannula

Study Overview
=================
Brief Summary
-----------------
The purpose of the study is to compare two ways (nasogastric tube (NGT) and nasoduodenal tube (NDT)) to provide nutrition to infants admitted to the hospital for viral bronchiolitis and who require high flow nasal cannula therapy.

Official Title
-----------------
Comparison Between Gastric and Post Pyloric Tube Feedings in Children With Bronchiolitis Requiring High Flow Nasal Cannula

Conditions
-----------------
Enteral Feeding in Bronchiolitis

Intervention / Treatment
-----------------
* Device: Nasogastric tube (NGT) feeding
* Device: Nasoduodenal tube (NDT) feeding


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: - All admitted patients for bronchiolitis requiring high flow nasal cannula therapy at Children's Memorial Hermann Exclusion Criteria: Patients with craniofacial abnormalities that prevent tube placement. Patients requiring CPAP and mechanical ventilation are also excluded from the study. Patients with past surgeries compromising esophageal sphincter tone such as fundoplication or congenital diaphragmatic hernia surgery are excluded. Patients transferred to and from PICU are also excluded from the study.

Ages Eligible for Study
-----------------
Maximum Age: 12 Months

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: nasogastric tube (NGT) feeding<br> | Device: Nasogastric tube (NGT) feeding<br>* A nasogastric tube goes from the nose to the stomach.<br>|
| Active Comparator: nasoduodenal tube (NDT) feeding<br> | Device: Nasoduodenal tube (NDT) feeding<br>* A nasoduodenal tube goes from the nose to the duodenum.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Length of Respiratory Supprt |  | from the time of hospital admission to discharge (about 6 days) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of Participants With Emesis |  | from the time of hospital admission to discharge (about 6 days) | 
| Peak Respiratory Support in Liters Per Minute |  | from the time of hospital admission to discharge (about 6 days) | 
| Number of Chest X-rays Obtained Among All Participants |  | from the time of hospital admission to discharge (about 6 days) | 
| Number of Participants Who Revisited the Emergency Room (ER) |  | 7 days after discharge from hospital | 
| Number of Participants Who Revisited the Emergency Room (ER) |  | 30 days after discharge from hospital | 
| Number of Participants Who Were Readmitted to the Hospital |  | 7 days after discharge from initial hospital visit | 
| Number of Participants Who Were Readmitted to the Hospital |  | 30 days after discharge from initial hospital visit |