Cohort of Chronic Pain Patients

Study Overview
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Brief Summary
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Chronic pain affects approximately 20% of adults, 50% of the elderly population and over 1.5 billion people worldwide. Societal and economic issues are also crucial, as 60% of people with pain are less able or unable to work and 20% say they have lost their jobs because of pain. The overall cost of chronic pain is estimated at around 300 billion euros in the EU. Unfortunately, current treatments for chronic pain have limited effectiveness and important adverse effects. Pain clinics, which support the most complex and refractory cases of chronic pain, as well as general practitioners and patients expect improvements, both in terms of therapeutic efficacy and organization of care. In order to allow the characterization and a personalized follow-up of chronic pain patients, we have created e-DOL, a smartphone application for patients and a web platform for healthcare professionals in pain clinics. The purpose of this study is to create an e-cohort for the research, and characterization and follow-up of chronic pain patients.

Detailed Description
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This first French e-cohort of chronic pain patients will allow real-life follow-up in order to generate big data including various information on chronic pain, associated-comorbidities, pain impacts on sleep, activity and psycho-emotional parameters, sociodemographic characteristics and pain treatments. These data will be collected with he eDOL tool (smartphone application for patients and web platform for caregivers in pain clinics), integrating numerous repeatable questionnaires, weekly barometers, a therapeutic education module and a conversational agent (chat bot). All of these data will also be linked with French health insurance care data in order to get an overview of comorbidities and patient care consumption in a medico-economic approach. The study will include 20 pain clinics and a minimum of 5000 patients followed for 24 months.

Official Title
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Constitution and Analysis of a Cohort of Patients Followed in Pain Clinics and at Home in Real Life

Conditions
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Chronic Pain

Intervention / Treatment
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* Other: eDOL


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All patients with chronic pain patients equipped and regular users of a smartphone Non-opposition to participation in the study Exclusion Criteria: Patient unable to understand or answer questionnaires

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| chronic pain patients<br>All adult patients followed-up in participating pain clinics | Other: eDOL<br>* e-health tool (mobile app for patients and web platform for caregivers in pain clinics)<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| multidimensional characterisation of chronic pain patients | Multimodal exploratory analysis of the determinants and repercussions of chronic pain, and their evolution in a real-life context, taking into account all environmental events likely to influence chronic pain (treatments, history, co-morbidities, etc.). | 5 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Multivariate descriptive analyses | Study the relationships between the measured criteria | 5 years | 
| Longitudinal analyses | Describe the distribution and temporal evolution of the measured variables | 5 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Chronic Pain, e-Health