Comparative Study inTreatment of Trigeminal Neuralgia

Study Overview
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Brief Summary
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This study aims to evaluate the results of percutaneous radiofrequency rhizotomy and the effectiveness of microvascular decompression for the treatment of trigeminal neuralgia and Comparing between them according the different outcome parameters.

Detailed Description
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This is prospective case -series hospital based study, will be conducted on 40 patients with trigeminal neuralgia treated either by percutaneous radiofrequency trigeminal rhizotomy or microvascular decompression at Sohag University Hospitals, between march 2021 and June 2022 and we will divide the the patients into two groups ,one group will be treated with percutaneous radiofrequency trigeminal rhizotomy and the other group will be treated with microvascular decompression and we will asses the results with the Barrow Neurological Institute Pain Intensity Score .

Official Title
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Comparative Study Between Microvascular Decompression and Percutaneous Radiofrequency Rhizotomy for Treatment of Trigeminal Neuralgia

Conditions
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Trigeminal Neuralgia

Intervention / Treatment
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* Procedure: percutaneous radiofrequency trigeminal rhizotomy
* Procedure: Microvascular decompression of the trigeminal nerve


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Failed medical treatment more than 6 months Exclusion Criteria: Coagulation disorder or hemorrhagic disease; Mental illness and inability to cooperate;
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: prospective case -series hospital based study
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: radiofrequency group<br>it is the group that will be treated with Percutaneous Radiofrequency Rhizotomy | Procedure: percutaneous radiofrequency trigeminal rhizotomy<br>* percutaneous radiofrequency trigeminal rhizotomy is a perctaneous procedure that ablate the sensory part of the nerve and<br>|
| Active Comparator: Microvascular decompression group<br>it is the group that will be treated with Microvascular decompression | Procedure: Microvascular decompression of the trigeminal nerve<br>* Microvascular decompression is a procedure that decompress the nerve from vascular conflict<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Barrow Neurological Institute Pain Intensity Score | I (no pain, no medication), II (occasional pain, not requiring medication), III (some pain, controlled with medication), IV (some pain, not controlled with medication) V (severe pain, no pain relief with medication). | 3 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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trigeminal neuralgia