Study on Application of Suturing Parathyroid Markers in Thyroid Cancer Surgery

Study Overview
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Brief Summary
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To study the protective effect of suture parathyroid marker method on the function of parathyroid gland in thyroid cancer surgery

Detailed Description
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This is a prospective randomized controlled study.In the experimental group, the suture parathyroid marker method was used to mark the parathyroid gland at the first time when it shows, and this marker was further used to identify and locating the inferior parathyroid marker in subsequent central region dissection. In the control group, the central area was routinely cleaned without suture parathyroid marker .

Official Title
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Study on Application of Suturing Parathyroid Markers in Thyroid Cancer Surgery

Conditions
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Thyroid Cancer, Hypoparathyroidism, Marker; Structural, Complication of Surgical Procedure, Parathyroid Function Low Adverse Event

Intervention / Treatment
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* Procedure: The suture marks the location of the parathyroid gland


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients with thyroid cancer who need central compartment dissection Routine neck incision surgery Patients undergoing primary neck surgery Exclusion Criteria: Benign thyroid tumor patients Selecting patients with endoscopes, small incisions, or robotic surgery Patients with hyperparathyroidism

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: Control group<br>Routine thyroidectomy and central lymph node dissection | |
| Experimental: Parathyroid marker group<br>When the lower parathyroid gland is first seen, the parathyroid gland is sutured with a suture during the operation, and then during this subsequent cleaning, rapid parathyroid localization and parathyroid glands are performed through this marker. | Procedure: The suture marks the location of the parathyroid gland<br>* When the lower parathyroid gland is first seen, the parathyroid gland is sutured with a suture during the operation, and then during this subsequent cleaning, rapid parathyroid localization and parathyroid glands are performed through this marker. Vascular protection.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The stitch marking operation time | The time required for making a parathyroid marker by a suture method | During surgery | 
| Specimen inspection time | The time required for finding parathyroid glands in surgical specimens | During surgery | 
| The number of transplanted parathyroid glands | The number of parathyroid glands required for autotransplantation of parathyroid glands | When the surgery is completed | 
| Parathyroid hormone level testing | Parathyroid hormone levels before and after surgery | 0 days, 1 day, 2 weeks after surgery | 
| Calcium levels | Calcium level before and after surgery to detect | 0 days, 1 day, 2 weeks after surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Thyroid Cancer, Hypoparathyroidism, parathyroid marker