Impact of Duration of Untreated Manic Episodes on Clinical Outcome

Study Overview
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Brief Summary
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The current study is cross sectional retrospective study, included 100 patients were diagnosed as mood disorder bipolar I (manic episodes) according to DSM5, patients recruited from inpatient psychiatric unit at department of Neurology and Psychiatry, Assiut University hospitals The current work is designed to study the effect of duration of untreated bipolar disorder on clinical outcome ( severity , residual symptoms ,duration of hospital admission) and to study factors affecting duration of untreatment in Upper Egypt.

Detailed Description
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Mood disorder carries a major burden in our country as it represents 15% of inpatients and 20% of outpatients in mental hospitals in Egypt The current work is designed to study the effect of duration of untreated bipolar disorder on clinical outcome ( severity , residual symptoms ,duration of hospital admission) and to study factors affecting duration of untreatment in Upper Egypt. The current study is cross sectional retrospective study, included 100 patients were diagnosed as mood disorder bipolar I (manic episodes) according to DSM5, patients recruited from inpatient psychiatric unit at department of Neurology and Psychiatry, Assiut University hospitals

Official Title
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Impact of Duration of Untreated Bipolar Disorder (Manic Episodes) on Clinical Outcome

Conditions
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Patients Diagnosed With Bipolar Disorder ( Manic Episodes) and Delayed Diagnosis

Intervention / Treatment
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* Other: young mania rating scale


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: -Age group between 18 to 45 years old. Patients diagnosed as mood disorder bipolar I manic episode according to DSM V(2). Clearly consenting to participate in the study. Exclusion Criteria: -Mood disorder due to substance abuse. Patients in depressive episodes. other mental disorders

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| less than 2 episodes<br>Patients were classified into 3 groups according to number of episodes (1-2 episodes, 3-5 episodes, more than 5 episodes) | Other: young mania rating scale<br>* questionnaires to the patients and their family after their written consent<br>* Other names: socioeconomic scale;|
| 2-5 episodes<br>Patients were classified into 3 groups according to number of episodes (1-2 episodes, 3-5 episodes, more than 5 episodes) | Other: young mania rating scale<br>* questionnaires to the patients and their family after their written consent<br>* Other names: socioeconomic scale;|
| more than 5 episodes<br>Patients were classified into 3 groups according to number of episodes (1-2 episodes, 3-5 episodes, more than 5 episodes) | Other: young mania rating scale<br>* questionnaires to the patients and their family after their written consent<br>* Other names: socioeconomic scale;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| measure the effect of duration of untreated bipolar disorder on severity (young mania rating scale on admission | To study the effect of duration of untreated bipolar disorder (manic episodes) on clinical outcomes (severity). | one year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| To measure the effect of duration of untreated bipolar disorder (manic episodes) on clinical outcomes (severity, residual symptoms, duration of admission). | residual symptoms measured by young mania rating scale on discharge | one year |