Psychosocial Outcomes and Transition Readiness in JIA

Study Overview
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Brief Summary
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It is widely acknowledged that the transition from paediatric to adult health services should be a multidimensional and multidisciplinary process that addresses the medical, psychosocial, and educational needs of adolescents and young adults (AYA). Despite this, there is currently a scarcity of research examining the relationships between psychosocial factors (e.g., anxiety, social support) and transition readiness in AYA with juvenile idiopathic arthritis (JIA). This study therefore aimed to examine the relationships between psychosocial factors and transition readiness in pre-transfer adolescents and post-transfer young adults aged 10-25 years diagnosed with JIA at a single centre. In total, 40 adolescents aged 10-16 years together with a parent/guardian, will take part at Sheffield Children's Hospital and 40 young adults aged 16-25 years will take part at Sheffield Teaching Hospitals. Participants will be asked to complete a battery of self-report questionnaire measuring psychosocial factors (anxiety/depression, social support, family functioning, health-related quality of life) and transition readiness (transition knowledge and skills, self-efficacy). JIA disease severity was also measured during clinic appointments. This study has received full ethical approval, and all participants will give their written informed assent or consent before taking part. The results from this research will be important in better understanding which psychosocial factors affect how ready young people with JIA feel to move from paediatric to adult rheumatology services. We hope this research will inform further work to help target psychological interventions in this group of patients.

Official Title
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Describing Relationships Between Psychosocial Outcomes and Readiness for Transition in Adolescent and Young Adult Patients With Juvenile Idiopathic Arthritis - a Pilot Study

Conditions
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Juvenile Idiopathic Arthritis

Participation Criteria
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Eligibility Criteria
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Patient Inclusion Criteria: Aged 10-25 years Diagnosis of juvenile idiopathic arthritis (including all ILAR subtypes except 'systemic arthritis' and 'undifferentiated arthritis') Juvenile idiopathic arthritis managed by Sheffield Children's Hospital or Sheffield Teaching Hospitals Fluent in verbal and written English Patient Exclusion Criteria: Aged <10 years or >25 years Diagnosis of juvenile idiopathic arthritis ILAR subtypes 'systemic arthritis' or 'undifferentiated arthritis') Diagnosis of uveitis Non-fluent in verbal and written English

Ages Eligible for Study
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Minimum Age: 10 Years
Maximum Age: 25 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Pre-Transfer Patients aged 10-16 years<br> | |
| Post-Transfer Patients aged 16-25 years<br> | |
| Parents/Guardians of Pre-Transfer Patients<br> | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Generalised Anxiety | Generalised Anxiety Disorder-7 Questionnaire (Spitzer et al., 2006) | 1 day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Depression | Patient Health Questionnaire-9 Questionnaire (Spitzer et al., 1999) | 1 day | 
| Health-related quality of life | Paediatric Quality of Life Arthritis Module (Varni et al., 2002) | 1 day | 
| Social support | Bath Adolescent Pain Questionnaire Social Support Subscale (Eccleston et al., 2005) | 1 day | 
| Family functioning | Bath Adolescent Pain Questionnaire Family Functioning Subscale (Eccleston et al., 2005) | 1 day | 
| Prosocial and problem behaviours | Strengths and Difficulties Questionnaire (Goodman, 1997) | 1 day | 
| JIA disease severity (JADAS-3) | JADAS-3 is a composite score of patient VAS score, physician VAS score, active joint count | 1 day |