Music Therapy in Obsessive Compulsive Disorder

Study Overview
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Brief Summary
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Previous studies have highlighted the potential therapeutic benefits of receptive individual music therapy as an adjunct to standard care, in a variety of psychiatric ailments including mood and anxiety disorders. However, the role of music in the treatment of obsessive compulsive disorder have not been investigated to date. The present study therefore aimed to investigate the efficacy of music therapy as an adjunct to standard treatment, on obsessions in patients with treatment-naïve OCD. Moreover, given the fact that a significant proportion of patients with OCD have other comorbid mood or anxiety disorders, the question of whether therapeutic benefits of music could be expanded to also affect concurrent depressive and anxiety symptoms was explored.

Official Title
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A Randomized Clinical Trial of Music Therapy as an Adjunct to Standard Treatment for Obsessive Compulsive Disorder and Co-morbid Anxiety and Depression in Iran

Conditions
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Obsessive-Compulsive Disorder, Anxiety, Depression

Intervention / Treatment
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* Drug: Selective serotonin re-uptake inhibitor
* Behavioral: Cognitive Behavioral Therapy
* Other: Music therapy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: were at least 18 years or older; had axis I diagnosis of OCD according to the criteria delineated by the diagnostic and statistical manual of mental disorders - fourth edition diagnosed by an experienced psychiatrist had not received treatment previously for the disorder agreed to partake in the study Exclusion Criteria: refused to partake in the study

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Standard treatment + music therapy<br>Selective serotonin re-uptake inhibitor plus cognitive behavioral therapy. Music therapy encompassing 12 half-hour sessions of therapist-supervised receptive music therapy scheduled over four weeks | Drug: Selective serotonin re-uptake inhibitor<br>* A medication of selective serotonin re-uptake inhibitor (SSRI) family, Behavioral. The type and dosage of the medication was decided by the treating psychiatrist.<br>* Other names: Pharmacotherapy;Behavioral: Cognitive Behavioral Therapy<br>* Cognitive Behavioral Therapy for obsessive compulsive disorder carried out by a psychologist.<br>* Other names: Psychotherapy;Other: Music therapy<br>* 12 sessions of 30-minute individual-based receptive music therapy, supervised by the treating psychiatrist.<br>* Other names: Receptive music therapy;|
| Active Comparator: Standard treatment only<br>Selective serotonin re-uptake inhibitor plus cognitive behavioral therapy. | Drug: Selective serotonin re-uptake inhibitor<br>* A medication of selective serotonin re-uptake inhibitor (SSRI) family, Behavioral. The type and dosage of the medication was decided by the treating psychiatrist.<br>* Other names: Pharmacotherapy;Behavioral: Cognitive Behavioral Therapy<br>* Cognitive Behavioral Therapy for obsessive compulsive disorder carried out by a psychologist.<br>* Other names: Psychotherapy;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Obsession (Maudsley Obsessive-Compulsive Inventory) | Post-intervention scores on Maudsley Obsessive-Compulsive Inventory | 1 month | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Obsession subtype (Maudsley Obsessive-Compulsive Inventory sub-types) | Post-intervention scores on Maudsley Obsessive-Compulsive Inventory sub-types | 1 month | 
| Anxiety symptoms (Beck Anxiety Inventory) | Post-intervention scores on Beck Anxiety Inventory | 1 month | 
| Depressive symptoms (Beck Depression Inventory - Short Form) | Post-intervention scores on Beck Depression Inventory - Short Form | 1 month | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Obsessive Compulsive Disorder, Music Therapy/methods, Combined Modality Therapy, Anxiety Disorders/therapy