The Impact of Physical Activity on the Postoperative Symptoms, Complications, and Quality of Life Among Lung Cancer

Study Overview
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Brief Summary
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The purpose of this study is to examine the impact of physical activity on the postoperative symptoms, complication, and quality of life.

Detailed Description
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Non-small cell lung cancer (NSCLC) survivor is increasing as developing early diagnosis and perioperative management. Despite multidisciplinary treatment, Surgery is the primary treatment option for cure in NSCLC. The patients with lung cancer who underwent surgery have limitation of pulmonary function and high risk of co-morbidities. Perioperative physical activity has been shown to reduce symptoms and prevent complications, improve long term quality of life after surgery. But validated exercise regimen has not been established for lung cancer patients. Therefore, Evidence-based guideline focusing on lung cancer after surgery is needed.

Official Title
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The Impact of Physical Activity on the Postoperative Symptoms, Complications, and Quality of Life Among Lung Cancer Survivors: A Prospective Cohort Study

Conditions
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Lung Neoplasms

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients who are diagnosed with lung cancer Patients who are able to walk with ECOG (Eastern Cooperative Oncology Group) performance status < 1 Patients who understand the purpose of this study and provide the written informed consent Exclusion Criteria: Patients who have difficulty for walking Patients with history of other cancer in the last 3 years Patients with neoadjuvant chemotherapy and/or radiation therapy Patients who are diagnosed with recurrent lung cancer or multiple cancer Foreigner of patients from overseas who are not able regularly participate in this study

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The change of quality of life: (EORTC QLQ) core30 (C30) | The change of quality of life is measured using the European Organization for Research Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ) core30 (C30). The scale for quality of life is transformed into a score from 0 to 100, derived by 4-point Likert scale. A higher score represents a higher level of quality of life. | Before surgery (baseline), and 1, 6, 12, 24, 36, 48, and 60 months after surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative pulmonary complications | Incidence of pulmonary complications including air leak, atelectasis, pleural effusion, pneumonia, etc. | Within 30 days after surgery | 
| The change of symptom | The change of symptom is measured using the European Organization for Research Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ) lung cancer module 13 (LC13). The scale for symptom is transformed into a score from 0 to 100, derived by 4-point Likert scale. A higher score represents a higher level of symptom. | Before surgery (baseline), and 1, 6, 12, 24, 36, 48, and 60 months after surgery |