Satiety Study of a Carbohydrate Meal to a Highly Viscous Gel Meal

Study Overview
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Brief Summary
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To evaluate the effects of Konjac on satiety and subsequent food intake in healthy individuals.

Official Title
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Comparing the Satiety Scores of a Carbohydrate Meal to a Meal of Equal Volume in Which Half of the Volume is Replaced With a Highly Viscous Gel.

Conditions
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Obesity

Intervention / Treatment
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* Dietary Supplement: Konjac noodles
* Dietary Supplement: Carbohydrate and Konjac Noodles
* Dietary Supplement: Carbohydrate noodles


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Men and women Age 18-65 years Having a BMI of 18.5 - 25 kg/m2 No presence of major disease Exclusion Criteria: Known history of liver or kidney disease, diabetes, hypertension, stroke or myocardial infarctions, thyroid disease, gastrointestinal disease, AIDS or AIDS-related complications; subjects using prescription medications or Natural Health Products; Subjects will be excluded if they have any condition which, in the opinion of the investigator, might jeopardize the health and safety of the subject or study personnel, or adversely affect the study results

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Placebo Comparator: Carbohydrate Noodles<br>0g Konjac Noodles | Dietary Supplement: Konjac noodles<br>* Replacement of carbohydrate noodles with non-caloric Konjac noodles (viscous gel meal)<br>* Other names: Scarborough, Ontario MIW 2P7;Dietary Supplement: Carbohydrate and Konjac Noodles<br> <br> * Other names: Bannockburn, Il 60015;Dietary Supplement: Carbohydrate noodles<br> <br> * Other names: Bannockburn, Il 60015;|
| Experimental: Carbohydrate and Konjac Noodles<br>Half Carbohydrate and Half Non-Caloric Konjac Noodles - 122.5g Konjac | Dietary Supplement: Konjac noodles<br>* Replacement of carbohydrate noodles with non-caloric Konjac noodles (viscous gel meal)<br>* Other names: Scarborough, Ontario MIW 2P7;Dietary Supplement: Carbohydrate and Konjac Noodles<br> <br> * Other names: Bannockburn, Il 60015;Dietary Supplement: Carbohydrate noodles<br> <br> * Other names: Bannockburn, Il 60015;|
| Experimental: Konjac Noodles<br>Non-Caloric Konjac Noodles (viscous gel meal) - 240g Konjac | Dietary Supplement: Konjac noodles<br>* Replacement of carbohydrate noodles with non-caloric Konjac noodles (viscous gel meal)<br>* Other names: Scarborough, Ontario MIW 2P7;Dietary Supplement: Carbohydrate and Konjac Noodles<br> <br> * Other names: Bannockburn, Il 60015;Dietary Supplement: Carbohydrate noodles<br> <br> * Other names: Bannockburn, Il 60015;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Objective Satiety | Objective satiety will be measured through subsequent food intake. At each visit, participants will consume a pre-weighed snack (wafer cookies) that will be administered ad libitum at 90mins after consumption of the test meal. Subsequent food intake will be calculated by weighing the amount of the snack food left after consumption. | 90 minutes | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Subjective Satiety | At each visit, participants will record their subjective satiety ratings using a 100 mm visual analogue scale and these rating will be combined into a total subjective appetite score using the formula (Q1+Q2+(100-Q3)+Q4)/4. | 90 minutes |