MP3 (Microperimeter 3) Reproducibility in Healthy Subjects and Macular Patients

Study Overview
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Brief Summary
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The aim of the present study is to investigate the reproducibility of the MP3 and to compare the results with conventional perimetry using the Octopus 101 in healthy subjects and patients with macular disease.

Official Title
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Reproducibility of Microperimetry Using Nidek MP3 (Microperimeter 3) in Healthy Subjects and Patients With Macular Disease - Pilot Study

Conditions
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Macular Degeneration

Participation Criteria
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Eligibility Criteria
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Inclusion criteria for healthy subjects Men and Women aged 18 and older Written informed consent Normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant Normal ophthalmological findings unless the investigator considers an abnormality to be clinically irrelevant Inclusion criteria for macular disease patients Men and Women aged 18 and older Written informed consent Presence of a macular disease (such as dry or exudative age-related macular degeneration, diabetic maculopathy, epiretinal membrane) Any of the following will exclude a subject from the study: Any opacities (corneal scar, dense cataract) which interferes with the study relevant measurements Visual acuity < 0.1 (Snellen)

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Healthy subjects<br>Men and Women aged 18 and older Normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant Normal ophthalmological findings unless the investigator considers an abnormality to be clinically irrelevant | |
| Age-related macular degeneration patients<br>Men and Women aged 18 and older Presence of a macular disease (such as dry or exudative age-related macular degeneration, diabetic maculopathy, epiretinal membrane) | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Reproducibility of retinal sensitivity measurements using microperimetry | Two study measurements are scheduled within one week. Test-retest reproducibility will be assessed for retinal sensitivity using the coefficient of repeatability and Bland-Altman diagrams. | Two measurement within one week | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Comparison of reproducibility of retinal sensitivity measurements assessed with microperimetry and conventional perimetry | In addition to microperimetry conventional perimetry will be performed and reproducibility of both devices will be compared. | Two measurement within one week | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Retina, Perimetry