Exercise Therapy for Femoroacetabular Impingement Syndrome

Study Overview
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Brief Summary
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The aim of the clinical trial is to investigate the characteristics of patients, who respond vs. not respond to exercise therapy for the nonsurgical management of femoroacetabular impingement syndrome (FAIS).

Detailed Description
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Patients with a diagnosis of FAIS will be recruited from 2 clinical centers and will receive exercise therapy (study intervention). Exercise therapy is a semi-standardized intervention and will last 12 weeks (3 months). Hip pain, function and quality of life will be assessed using a patient-reported questionnaire at baseline, 3, 6 and 12 months' follow-up. Hip joint contact pressure will be evaluated using motion analysis and modelling at baseline, 3 and 12 months' follow-up. Hip morphology will be evaluated using imaging at baseline and hip surgery rate will be evaluated at 6 and 12 months' follow-up.

Official Title
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The Effect of Patients' Characteristics on the Responsiveness to Exercise Therapy for the Management of Femoroacetabular Impingement Syndrome: a Multi-center, Single-group, Intervention Study

Conditions
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Femoroacetabular Impingement Syndrome

Intervention / Treatment
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* Other: Exercise therapy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age: 18 to 50 years; Diagnosis of FAIS; Availability of magnetic resonance arthrography and anteroposterior pelvic radiography of the involved hip; Signed informed consent form. Exclusion Criteria: Previous hip surgery; Any surgery on the lower extremities in the last 6 months; Hip dysplasia: lateral center edge angle <25°; Hip osteoarthritis: Tönnis grade >1; BMI: >35 kg/m2; Significant cardiopulmonary diseases.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Exercise therapy<br>Exercise therapy consists of improving dynamic hip joint stability by means of hip-specific and functional lower limb strengthening, core stability and postural balance exercises. | Other: Exercise therapy<br>* Education Hip-specific strengthening exercises Functional lower limb strengthening exercises Core stability exercises Postural balance exercises<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in hip pain, function and quality of life | Hip pain, function and quality of life will be assessed using the International Hip Outcome Tool - 33 Items | Baseline to 6 months' follow-up | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in hip pain, function and quality of life | Hip pain, function and quality of life will be assessed using the International Hip Outcome Tool - 33 Items | Baseline to 12 months' follow-up | 
| Change in hip pain, function and quality of life | Hip pain, function and quality of life will be assessed using the International Hip Outcome Tool - 33 Items | Baseline to 3 months' follow-up | 
| Change in hip joint contact stress | Hip joint contact pressure will be assessed using modelling | Baseline to 3 months' follow-up | 
| Change in hip joint contact stress | Hip joint contact pressure will be assessed using modelling | Baseline to 12 months' follow-up | 
| Hip morphology | Hip morphology will be assessed using imaging | Baseline | 
| Change in sport activity level | Sport activity level will be assessed using the Hip Sports Activity Scale | Baseline to 3 months' follow-up | 
| Change in sport activity level | Sport activity level will be assessed using the Hip Sports Activity Scale | Baseline to 6 months' follow-up | 
| Change in sport activity level | Sport activity level will be assessed using the Hip Sports Activity Scale | Baseline to 12 months' follow-up | 
| Hip surgery rate | Number of patients who will decide to undergo hip surgery | 6 months' follow-up | 
| Hip surgery rate | Number of patients who will decide to undergo hip surgery | 12 months' follow-up | 
| Dropout | Number of patients who will not complete the non-surgical intervention protocol | 3 months' follow-up |