Physical Therapy for Diabetes Mellitus

Study Overview
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Brief Summary
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Background: The aim of this study to compare the effect of moderate exercises versus light exercises on patients with type 2 diabetes mellitus. Methods: This 3-month, 2-arm cluster randomized controlled trial involved 60 patients aged between 35and 60 years divided randomly into two groups. Group 1 received 30 minutes of aerobic exercise at 40-60% of maximum heart rate. Group 2,Treated by walking30 minutes daily divided into 5minutes every 2 hours to break sedentary position for 12 hours daily. Results: At the base line no significant difference were found in both groups in all parameters. After three months of treatment, there is no significant difference in all parameters BMI, p=0.111, waist to hip ratio, p=0.245, 6 minutes' walk, p=0.614, blood glucose, p=0.105 and sf-36, p=0.106. The study approved by ethical committee of faculty of physical therapy, Cairo University REC/012/002607. Conclusion: Light exercise has the same effect on blood glucose as moderate exercise, so just walking for 5 minutes every 2 hours can be useful for patients with type 2 diabetes mellitus.

Detailed Description
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78 patients have been chosen from department of internal medicine, Cairo university hospitals, Egypt. 8 patients were excluded because 3 have chronic renal failure, 3 have cardiopulmonary diseases and 2 have severe osteoarthritis of knees. They were divided randomly into two groups, group one will be treated by moderate exercises and group and group 2 will be treated by light exercises. after division all the procedures were explained to patients.5 patients refused to sign informed consent and excluded from the study.33 patients in group1 and 32 patients in group2.3patients dropped in group1 and excluded from the study and two patients didn't continued the programmed treatment in group 2 and their data removed. Thirty patients in each group signed an informed consent and complete the treatment program.

Official Title
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Effect of Moderate Exercise Versus Breaking Sedentary by Light Exercise on Patients With Type 2 Diabetes Mellitus

Conditions
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Diabetes Mellitus

Intervention / Treatment
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* Other: Moderate exercises


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Type2 diabetes mellitus. Age between 35 and 60. BMI≥30 Exclusion Criteria: Renal failure. Cardiopulmonary diseases. Lower limb diseases or fracture.

Ages Eligible for Study
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Minimum Age: 35 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: 2-arm cluster randomized controlled trial involved 60 patients aged between 35and 60 years divided randomly into two groups. Group 1 received 30 minutes of aerobic exercise at 40-60% of maximum heart rate. Group 2,Treated by walking30 minutes daily divided into 5minutes every 2 hours to break sedentary position for 12 hours daily.
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: moderate exercises group<br>Patients received 30 minutes of aerobic exercise at 40-60% of maximum heart rate | Other: Moderate exercises<br>* Group 1 received 30 minutes of aerobic exercise at 40-60% of maximum heart rate. Group 2,Treated by walking30 minutes daily divided into 5minutes every 2 hours to break sedentary position for 12 hours daily.<br>* Other names: Light exercises;|
| Experimental: Light exercises group<br>Patients treated by walking30 minutes daily divided into 5minutes every 2 hours to break sedentary position for 12 hours daily. | Other: Moderate exercises<br>* Group 1 received 30 minutes of aerobic exercise at 40-60% of maximum heart rate. Group 2,Treated by walking30 minutes daily divided into 5minutes every 2 hours to break sedentary position for 12 hours daily.<br>* Other names: Light exercises;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| BMI | Weight divided by square of the height | 12 week | 
| Waist to hip ratio | Circumference of the waist at umbalicus/ circumference of gluteal region | 12 weeks | 
| 6 minutes walk distance | meters walked in 6 minutes | 12 weeks | 
| Blood glucose | mg/dl | 12 weeks | 
| SF-36 | degree | 12 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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moderate exercises, light exercises, obesity, sedentary behavior