Descriptive Study Regarding Ambulant Screening During COVID-19 Pandemia

Study Overview
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Brief Summary
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Descriptive prospective study to investigate the prevalence of COVID 19 during ambulant screening

Detailed Description
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The exact prevalence of COVID-19 is unknown. Due to the relatively high number of diagnosed, symptomatic infections despite a strict policy, we expect a high prevalence of COVID 19 throughout the entire population. The risk that an asymptomatic carrier who is admitted to the hospital for a (semi)urgent surgery, treatment of investigation transfers the virus to the hospital staff is very high, and vice versa. This risk is even higher during surgery, where intubation is necessary. Therefore we would like to pre-screen all patients ambulantly on the presence of COVID 19 since there is no consensus for screening at the moment. The golden standard is the SARS CoV-2 PCR on the nasopharyngeal sample together with a CT scan of the lungs. Patients in which a bloodsample is taken as standard of care procedure in this ambulant screening will be asked to give more blood for further investigation. On top of this standard of care screening, we will perform a questionnaire at the pre-operative visit which evaluates the possible occurence of certain symptoms in the last 2 weeks. These symptoms are fever, anorexia, cough, diarrhea, sneezing, vomiting, dyspnea, headache, rhinorrhea, loss of smell, muscle pain, sputum, sore throat and fatigue. Patients were also asked if one of their housemates are affected by these symptoms. Furthermore, 2 weeks after surgery, patient will be contacted to phone in order to fill the same questionnaire.

Official Title
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Descriptive Study Regarding the Ambulant Screening Protocol for COVID-19 in Times of High SARS CoV-2 Prevalence

Conditions
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COVID 19

Intervention / Treatment
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* Other: Questionnaire


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All adult patients > 18 years scheduled for a (semi) urgent surgery, hematological or oncological treatment or elektrophysiciological investigations in the Jessa hospital Exclusion Criteria: Patients < 18 years Adult patients who are unable the give informed consent Language barrier

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Questionnaire|Questionnaire|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prevalence of symptoms | Prevalence of fever, cough, anorexia, fatigue, diarrhea, vomiting, dyspnee, sore throat and sputum | at the ambulant screening | 
| Prevalence of positive Sars CoV-2 PCR | Prevalence of positive COVID 19 tests in patients planned for surgery, treatment or investigation in the hospital | at the ambulant screening | 
| Prevalence of positive radiological findings | Prevalence of positive radiological findings in CT scans of the lungs of planned for surgery, treatment or investigation in the hospital | at the ambulant screening | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Prediction of symptoms | Prediction of symptoms of COVID 19, based on evaluated baseline questionnaire | 2 weeks after surgery or treatment | 
| Prediction of symptoms | Prediction of symptoms of COVID 19, based on radiological findings of CT scans | 2 weeks after surgery or treatment | 
| Prediction of symptoms | Prediction of symptoms of COVID 19, based on COVID 19 PCR results | 2 weeks after surgery or treatment |