What Happens in Vegas: PEP to PrEP Opportunities

Study Overview
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Brief Summary
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Observational study looking at barriers to care for individuals seeking care, Post Exposure Prophylaxis (PEP) after an actual or perceived exposure to HIV. Following PEP treatment subjects will be asked about there intent to transition to Pre-Exposure Prophylaxis (PrEP) and surveyed about barriers to care or perceptions of care

Detailed Description
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The primary objective of this study is to assess the rate of engagement in a PEP to PrEP HIV provider network for those patients presenting following a non-occupational HIV exposure. The development of a referral network and intensive clinical follow up of PEP patients will result in more patients appropriately initiating PEP, being referred to appropriate follow up, and post exposure transition and maintaining on PrEP (if indicated) at completion of the PEP medications.

Official Title
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What Happens in Vegas: Identifying Opportunities to Expand an HIV Prevention Network to Improve PEP and PrEP Delivery

Conditions
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Exposure to Human Immunodeficiency Virus (Event)

Intervention / Treatment
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* Drug: Currently approved medications


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Actual or perceived non-occupational exposure to HIV, by self report, within 72 hours of enrollment and referred for care able and willing to provide informed consent available for 12 months of post expoure follow-up Southern Nevada Ryan White defined service area Exclusion Criteria: HIV+ at time of screeing via 4th genderation (Antibody/Antigen) testing Current PEP and/or PrEP product condrainidications as listed in the medication product insert.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: Currently approved medications|subjects will be treated according to current Department of Health and Human Services (DHHS) Center for Disease control and prevention (CDC), Society for Healthcare Epidemiology of American (SHEA guidelines for nPEP|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| rate of engagement | Assess the rate of engagement in a PEP to PrEP HIV prevention provider network for those patients presenting following a non-occupational HIV exposure | from enrollment to day 90 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| characteristics | Describe the characteristics of patients successfully engaging in HIV prevention via a patient collected survey using a qualtric survey. | from enrollment through end of study for all participants | 
| barriers | Identify and assess barriers to access to HIV prevention care including PEP in the period immediately following HIV exposure from a patient collected survey using a qualtric survey tool | from enrollment through end of study for all participants | 
| Network characteristics | Analyze the network characteristics that faciliate engagement in HIV prevention services from a patient collected survey using a qualtric survey tool | from enrollment through end of study for all participants | 
| transition barriers | Determine and assess to transitioning from PEP to PrEP from a patient collected survey using a qualtric survey tool | from enrollment through end of study for all participants | 
| Retention | Compare and contrast the barriers to access and ongoing retention to PrEP from a patient collected survey using a qualtric survey tool. | from enrollment through end of study for all participants | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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PEP, nPEP, Post Exposure Prophylaxis, non occupational exposure to HIV