Effects of a Dietary Supplement Containing L-Arabinose and Trivalent Patented Food-source of Chromium on Blood Glucose and Insulin

Study Overview
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Brief Summary
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This study was designed to examine changes in capillary blood glucose and venous insulin levels after a 70 gram oral sucrose challenge with and without simultaneous consumption of a dietary supplement containing L-Arabinose and a patented version of chromium (LA-Cr).

Detailed Description
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This study concluded that consumption of the LA-Cr supplement in conjunction with a 70-gram sucrose challenge led to a significant reduction of capillary blood glucose and venous insulin as compared to the sucrose challenge without the LA-Cr supplement. This finding may provide an important tool to reduce the adverse effects associated with elevated glucose and insulin levels.

Official Title
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A Combination of L-Arabinose and Chromium Lowers Circulating Glucose and Insulin Levels After Acute Oral Sucrose Challenge

Conditions
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Pre-diabetes

Intervention / Treatment
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* Dietary Supplement: L-Arabinose and Chromium
* Dietary Supplement: Sucrose without dietary Supplement


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: All study subjects were required to contact their family physician to ensure they had no medical conditions that would preclude their participation. Exclusion Criteria: Diabetics, and Those not approved by their physicians.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Sucrose with Dietary Supplement<br>Repeated measures on subjects taking 70 grams of sucrose along with taking a dietary supplement containing L-Arabinose and Chromium | Dietary Supplement: L-Arabinose and Chromium<br>* Consumed 70 grams of sucrose simultaneously taking a dietary supplement<br>* Other names: 70 grams of cane sugar along with supplement;|
| Active Comparator: Sucrose without Dietary Supplement<br>Consumed 70 grams of sucrose without simultaneously taking the dietary supplement | Dietary Supplement: Sucrose without dietary Supplement<br>* Repeated measures on subjects taking 70 grams of sucrose along with taking a dietary supplement containing L-Arabinose and Chromium<br>* Other names: 70 grams of cane sugar with supplement;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Fasting Blood Glucose | Finger-stick glucose measurements taken every 15 or 30 minutes after taking a 70 gram sucrose challenge with and without the dietary supplement | Every 15 to 30 minutes | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Fasting Blood Insulin Levels | A venipuncture blood test taken 30, 60, 90 and 120 minutes after taking a 70 gram sucrose challenge with and without taking the dietary supplement | Every 30 minutes | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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glucose, insulin, L-arabinose, Chromium