Yoga for Rheumatoid Arthritis

Study Overview
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Brief Summary
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The purpose of this study is to evaluate the impact of yoga on inflammatory arthritis and knee osteoarthritis.

Detailed Description
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Yoga is a set of ancient Indian theories and practices, focusing on unifying mind, body, and spirit, and promoting strength, balance, and flexibility. The physical aspect of yoga includes poses, breathing techniques, and relaxation. Inflammatory arthritis, a chronic disease characterized by inflammation of the lining of the joints, can cause long-term joint damage, resulting in chronic pain, loss of function, and disability. The primary objective of this study is to learn how people with inflammatory arthritis and knee osteoarthritis respond to an exercise program of yoga. To accomplish this, 30 persons with inflammatory arthritis or knee osteoarthritis will be randomly assigned to one of two groups. Group one will begin an immediate 8-week program of yoga classes consisting of 60-minute sessions, twice a week. Group two, or the waitlist control group, will receive 8 weeks of arthritis education followed by the same 8-week yoga program as group one. Participants also will have blood drawn, and complete various tests. The yoga classes will be taught by an experienced, certified yoga instructor, and are designed especially for the needs of people with inflammatory arthritis and knee osteoarthritis. This study will provide important data on integrating mind-body activities into the treatment of inflammatory arthritis and knee osteoarthritis.

Official Title
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Yoga for Persons With Rheumatoid Arthritis

Conditions
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Rheumatoid Arthritis, Osteoarthritis

Intervention / Treatment
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* Behavioral: yoga


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 18+ (RA only upper age limit 70) Confirmed or probable OA (using pre-specified criteria) OR Rheumatoid arthritis (participation approved by rheumatologist) Currently sedentary (physically active for 20 min < 3times/week) Exclusion Criteria: Inability to ambulate without use of assistive device Uncontrolled high blood pressure or existing heart condition Co-morbid inflammatory condition with overlapping symptoms (i.e., fibromyalgia) Surgery within 6 months

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Randomized controlled trial
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 1<br>8-week yoga program | Behavioral: yoga<br>* 8-week yoga program.<br>|
| No Intervention: 2<br>Usual care control | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Physical Health | Assessed using SF36 Physical Component Score | baseline, post intervention, follow-up | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mobility/Fitness | Change in flexibility, balance, strength, walk time | baseline, posttest, follow-up | 
| RA Disease Activity | DAS28 CRP score | baseline, post intervention, follow-up | 
| Psychological Function | Change in SF36 MCS, CES-D, PANAS, Perceived Stress and Arthritis Self Efficacy | baseline, , posttest, follow-up | 
| HRQL | Change in SF36 domains | baseline, post intervention, follow-up | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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inflammatory arthritis, rheumatoid arthritis, knee osteoarthritis, arthritis, yoga