The Role of TVSG and HS in Determining Endometrial Pathologies

Study Overview
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Brief Summary
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Although hysteroscopy (HS) and transvaginal ultrasonography (TVSG) are methods in the diagnosis of AUB, there is some suspicion about their efficacy. The aim of this study was to determine the efficacy and safety of HS and TVSG on diagnosing abnormal uterine bleeding(AUB) .216 women admitted to the investigators clinic (Sisli Ethal Training and Research Hospital, Obstetrics and Gynecology Department Obstetrics Service ) between 21-51 years of age. These patients were divided into two groups; menopause (71women) and pre-menopause (145 women). HS and endometrial sampling were performed both groups after TVSG.The success of these methods was assessed by kappa analysis

Official Title
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Ultrasound and Hysteroscopy's Place on the Diagnosis of Abnormal Uterin Bleeding

Conditions
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Abnormal Uterine Bleeding

Intervention / Treatment
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* Device: Transvaginal ultrasound
* Device: Hysteroscopy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients who have no history of hysteroscopy and curettage, patients who have no history of ovulatory dysfunction women who have active vaginal bleeding. Exclusion Criteria: presence of genital infections/PID presence of pregnancy presence of vaginal or cervical pathology causing vaginal bleeding women who are receiving hormonal treatment (COC/HRT) patients formerly diagnosed with endometrial pathology patients having coagulopathy women who are using intrauterine device.

Ages Eligible for Study
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Minimum Age: 21 Years
Maximum Age: 51 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Transvaginal ultrasound<br>Transvaginal ultrasound was applied 216 women with abnormal uterine bleeding.The transvaginal ultrasound diagnoses were compared with the received endometrial samples. | Device: Transvaginal ultrasound<br> <br> |
| Other: Hysteroscopy<br>Hysteroscopy was also performed under general anesthesia.Hysteroscopy was performed by a single operator (NNY).The operator and two supervising endoscopists were blinded to the ultrasound results.After the hysteroscopy, endometrial sampling was also done. The diagnoses were compared with the received endometrial samples. | Device: Hysteroscopy<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| accuracy of diagnostic performance transvaginal ultrasonography and hysteroscopy | The main outcome variable of the study was accuracy of diagnostic performance of transvaginal ultrasonography and hysteroscopy in premenopausal and menopausal women with abnormal uterin bleeding . | up to 12 month | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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transvaginal ultrasonography, hysteroscopy, abnormal uterine bleeding