Abdomen CT and Open Appendicectomy：New Diagnostic and Surgical Procedures

Study Overview
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Brief Summary
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The traditional open appendectomy in the clinical effect is not prefect, and for a long time there is no measurable improvement. The application of abdomen CT before surgery provides a new approach to the incision and new perception. In a randomized controlled trial of modified incision versus traditional incision. Length of hospital day was the primary terminus, while operating time, postoperative complication, scar and time to resume normal activity and work as secondary terminus.

Detailed Description
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Traditional open appendicectomy have many drawbacks, such as false-positive, cut infection, scar, extended cut, slower rehabilitation and return to work. In the past few years, in order to improve diagnostic accuracy, the abdomen CT is been general applied before appendicectomy, in addition to, a modified incision (MI) was designed based on it. Using a MI compare traditional incision (TI) to the patient including cut extended, operating time, cut infection, false-positive rate, rehabilitation and return to work. It seems that MI would prove superior to TI in terms of hospital day (primary terminus), with operating time, postoperative complication, scar and time to resume normal activity and work as secondary terminus.

Official Title
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Abdomen CT and Open Appendicectomy：New Diagnostic and Surgical Procedures

Conditions
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Wound Infection, Complication, Scar

Intervention / Treatment
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* Radiation: The application of abdomen CT
* Other: traditional incision


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients with a clinical diagnosis of acute appendicitis Exclusion Criteria: children under 14 are not included

Ages Eligible for Study
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Minimum Age: 15 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: traditional incision<br>traditional incision : McBurney incision,Rectus incision,Appendix Transverse incision or Tenderness point incision,it was invaginated at the discretion of the surgeon. | Other: traditional incision<br>* McBurney incision,Rectus incision,Appendix Transverse incision or Tenderness point incision,it was invaginated at the discretion of the surgeon.<br>|
| Experimental: modified incision<br>modified incision :The application of abdomen CT before surgery provides a new approach to the incision and new perception. | Radiation: The application of abdomen CT<br>* A modified incision(MI)was designed based on abdomen CT.Using a MI compare traditional incision(TI) to the patient including cut extended, operating time,cut infection, false-positive rate,rehabilitation and return to work.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| hospital day |  | 2 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| time to return to normal activity and work in days |  | up to 4 weeks | 
| operating time in minutes |  | 180 Minutes | 
| numbers of extended cut, numbers of infection,numbers of intraperitoneal abscess |  | 1 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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abdomen CT, open appendicectomy