Contingency Management to Promote Smoking Abstinence in Cancer Patients

Study Overview
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Brief Summary
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This is a smoking cessation treatment study. Patients who have a cancer or a suspected cancer who will undergo surgical removal of their cancer are eligible to participate in this study. A novel smoking cessation treatment will be provided to half of the participants in the study. All study participants will receive standard smoking cessation therapy including counseling and the nicotine patch.

Official Title
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Contingency Management to Promote Smoking Abstinence in Cancer Patients

Conditions
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Smoking Cessation

Intervention / Treatment
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* Combination Product: Contingency Management
* Combination Product: Standard Care


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 18 or older smoking 1 or more combustible tobacco products per day diagnosed with or suspicion of any type of operable cancer Exclusion Criteria: unstable psychiatric/medical conditions such as suicidal ideation, acute psychosis, or dementia non-English speaking use of alternative nicotine delivery systems (e.g., e-cigarettes, snus, etc) pregnant women

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Contingency Management<br> | Combination Product: Contingency Management<br>* Participants will receive 3-6 counseling sessions, nicotine patches & lozenges, and monetary payment delivered contingent on abstinence verified by CO breath test.<br>|
| Active Comparator: Standard Care<br> | Combination Product: Standard Care<br>* Participants will receive 3-6 counseling sessions, nicotine patches & lozenges, and CO breath test monitoring.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Abstinence Rates as assessed by self-report for past 7 days, Carbon Monoxide Breath Monitoring and/or Anabasine testing | Abstinence will be defined by 7 days by self-report of no tobacco products, confirmed by CO breath test less than or equal to 4ppm and/or urine anabasine levels less than or equal to 2 ng/ml | Changes between the study intake appointment to day of surgery, up to five weeks apart | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Abstinence Rates as assessed by self-report for past 7 days, Carbon Monoxide Breath Monitoring and/or Anabasine testing | Abstinence will be defined by 7 days by self-report of no tobacco products, confirmed by CO breath test less than or equal to 4ppm and/or urine anabasine levels less than or equal to 2 ng/ml | Three and Six months after surgery date |