3 Minutes Chair Rise Test (3CRT) in Patients With COPD

Study Overview
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Brief Summary
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Improvement in the functional functioning and dyspnea of COPD patients after a rehabilitation program (RHB) is assessed by exercise tests and questionnaires difficult to replicate outside specialized centers. In order to monitor the eventual decline of patients in the course of their RHB management, Chair Rise Tests (3CRT-1CRT-5STS) and short questionnaires were developed (CAT-DIRECT). The goal of this prospective, multicenter, real-life study is to compare the change in several functional function tests and questionnaires of quality of life and dyspnea related to daily activities. In addition, MCIDs of the 3CRT and the DIRECT questionnaire (Disability Related to COPS Tool) were specified.

Official Title
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Chair Rise Tests for a Simplified Evaluation of Functional Response After a Rehabilitation Program in Patients COPD.

Conditions
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Evaluations, Rehabilitation, COPD

Intervention / Treatment
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* Diagnostic Test: Chair Rise Tests and short questionnaire


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patient with COPD Gold II to IV Patient admitted for a rehabilitation program in real life Person affiliated to the Social Security or beneficiary of such a scheme Informed and written consent by patient or legal representative Exclusion Criteria: Patient limited by reduced locomotor activity or joint pain that compromises their participation in a rehabilitation program Patients with a performance less than 250 meters during 6MWT Non-stable cardiac disease Any other lung disease than COPD Person subject to a legal protection measure

Ages Eligible for Study
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Minimum Age: 40 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Intervention Model: Sequential Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: COPD patients<br>All convenient COPD patients admitted in real life for a rehabilitation program were included. Exercises consist on a Chair Rise Tests and short questionnaire were added to the usual tools for the evaluation. | Diagnostic Test: Chair Rise Tests and short questionnaire<br>* Exercises consist on a Chair Rise Tests and short questionnaire It is a functional test evaluating the number of chair rise over a given time and / or frequency. This test is combined with a questionnaire to collect quantitative and qualitative information: dyspnea and muscular fatigue at rest before the start of the test and at the end of the exercise Saturation at rest, and at the end of the exercise the number of total a chair rise<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change of number of rise during 3 minutes Chair Rise Test (3CRT) | The change of total number of rise during a 3 minutes Chair Rise Test (3CRT) from baseline | At Baseline, at 2 and 8 weeks. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change of number of rise during 1 minute Chair Rise Test (1CRT) | The change of total number of rise during a 1 minutes Chair Rise Test (3CRT) from baseline | At Baseline, at 2 and 8 weeks. | 
| Change of Time to perform 5 sit to stand | The change of Time to perform 5 sit to stand from baseline | At Baseline, at 2 and 8 weeks. | 
| The change of Total score for the DIsability RElated to COPD Tool (DIRECT) | Total Score | At Baseline and at 8 weeks. | 
| Difference in physiological response (SpO2 and HR) during the 3 Chair Rise Tests (3CRT-1CRT-5STS) | End SpO2 - End Heart Rate | At Baseline, at 2 and 8 weeks. | 
| Change in endurance time at constant power on cyclo ergometer, | The change of endurance time from baseline | At Baseline, at 2 and 8 weeks. | 
| Change of Voluntary Quadriceps force output | Change of Voluntary quadriceps force measurements (Mean of 3 maximal measurements) from baseline | At Baseline, at 2 and 8 weeks. | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Exercise tests, COPD, Rehabilitation