Circadian Rhythm Status and CS (Cesarean Section) Postoperative Pain

Study Overview
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Brief Summary
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Use huawei wristwatch to record maternal rhythm status and record the VAS score after cesarean section under combined spinal-epidural anesthesia. Based on this study the investigators intend to explore the correlation between maternal circadian rhythm status and postoperative pain after cesarean section.

Official Title
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Circadian Rhythm Status and CS (Cesarean Section) Postoperative Pain

Conditions
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Circadian Rhythm

Intervention / Treatment
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* Device: Huawei bracelet


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 20 to 45 ASA(American society of anesthesiologists) status II-III 37-42 weeks gestation undergo elective cesarean section with subarachnoid anesthesia participate in this study and sign informed consent Exclusion Criteria: Patients with contraindications of combined spinal and epidural anesthesia Patients with severe systemic disease Alcoholism and long-term use of anti-inflammatory and analgesic drugs Patients who were unable to cooperate or refused to participate in the trial with psychiatric disorder researchers considered unsuitable to participate in or unable to cooperate with the study

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Device: Huawei bracelet|Huawei bracelet was used to continuously record maternal respiration, heart rate, temperature and sleep data, and then calculate maternal circadian rhythm state|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Incidence of moderate and severe pain after cesarean section | number rating scale (NRS) for pain (0=no pain to 10=worst pain) >4 | From ending of the surgery to 24hours after cesarean section | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain intensity durig 0 to 6 hours after surgery | number rating scale (NRS) for pain (0=no pain to 10=worst pain) | From ending of the surgery to 6 hours after cesarean section | 
| Pain intensity durig 6 to 12 hours after surgery | number rating scale (NRS) for pain (0=no pain to 10=worst pain) | From 6 hours after cesarean section to 12 hours after cesarean section | 
| Pain intensity durig 12 to 24 hours after surgery | number rating scale (NRS) for pain (0=no pain to 10=worst pain) | From 12 hours after cesarean section to 24 hours after cesarean section | 
| Heart rate variability | Heart rate variability recorded by Huawei bracelet | From the time of inclusion in the study until the patient's postoperative discharge, assessed up to 1 week | 
| Body temperature variability | Body temperature variability recorded by Huawei bracelet | From the time of inclusion in the study until the patient's postoperative discharge, assessed up to 1 week | 
| Variability of patients' activity | Variability of patients' activity recorded by Huawei bracelet | From the time of inclusion in the study until the patient's postoperative discharge, assessed up to 1 week | 
| Percentage of deep sleep | Percentage of deep sleep evaluated by Huawei bracelet | From the time of inclusion in the study until the patient's postoperative discharge, assessed up to 1 week | 
| Percentage of rapid eye movement sleep | Percentage of rapid eye movement sleep evaluated by Huawei bracelet | From the time of inclusion in the study until the patient's postoperative discharge, assessed up to 1 week | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Pain, Circadian Rhythm, Cesarean Section