The Size of Pelvic Hematoma Can be a Predictive Factor for Angioembolization

Study Overview
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Brief Summary
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Unstable pelvic fracture with bleeding can be fatal, with a mortality rate of up to 40%. Therefore, early detection and treatment are important in unstable pelvic trauma. We investigated the early predictive factors for possible embolization in patients with hemodynamically unstable pelvic trauma. The purpose of this study was to predict the necessity of embolization and the timing of angiography using CT scans.

Detailed Description
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Background: Unstable pelvic fracture with bleeding can be fatal, with a mortality rate of up to 40%. Therefore, early detection and treatment are important in unstable pelvic trauma. We investigated the early predictive factors for possible embolization in patients with hemodynamically unstable pelvic trauma. Methods: From January 2011 to December 2013, 46 patients with shock arrived at a single hospital within 24 h after injury. Of them, 44 patients underwent computed tomography (CT) after initial resuscitation, except for 2 who were dead on arrival. Nine patients with other organ injuries were excluded. Seventeen patients underwent embolization. A single radiologist measured the width (longest length in axial view) and length (longest length in coronal view) of pelvic hematoma on CT scans. Demographic, clinical, and radiological data were reviewed retrospectively.

Official Title
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The Size of Pelvic Hematoma Can be a Predictive Factor for Angioembolization in Hemodynamically Unstable Pelvic Trauma

Conditions
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Multiple Pelvic Fractures

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients with shock (systolic blood pressure <90 mmHg) arrived at a single hospital within 24 h after injury after pelvic fracture Exclusion Criteria: declared dead on arrival patients with other organ injuries

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Embolization group<br>The group that underwent embolization after pelvic injury. | |
| Non-embolization group<br>The observed group of pelvic injuries without embolization | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Predictive factors for embolization in unstable pelvic fracture | The factors affecting embolization are analyzed by logistic regression analysis | 2 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The odds ratio of mortality rate between two groups | Obtain the difference in mortality rate between two groups | 2 years | 
| Cut-off values of pelvic hematoma width | Measure the length of pelvic hematoma using the ROC curve | 2 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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angioembolization, computed tomography