Hemostasis Using Radiofrequency Ablation for Track Bleeding

Study Overview
=================
Brief Summary
-----------------
This study aims to evaluate the usefulness of hemostasis using radiofrequency ablation for track bleeding that has occurred after percutaneous biopsy of the liver.

Detailed Description
-----------------
Purpose: To evaluate the usefulness of hemostasis using radiofrequency ablation for track bleeding after percutaneous liver biopsy. Method: Enroll patients who continue to bleed despite conservative treatment for track bleeding that has occurred after liver biopsy. Radiofreqeuncy ablation: Under monitoring vital signs and controlling pain with intravenous agents, the electrode is inserted into the bleeding focus. The bleeding focus is ablated. Hemostasis is evaluated by ultrasound (right after radiofrequency ablation), CT scan (after the radiofrequency ablation), and ultrasound (the day after radiofrequency ablation) If hemostasis fails using radiofrequency ablation, transarterial hepatic embolization is performed immediately.

Official Title
-----------------
Hemostasis Using Radiofrequency Ablation for Track Bleeding After Liver Biopsy

Conditions
-----------------
Bleeding

Intervention / Treatment
-----------------
* Procedure: radiofrequency ablation


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Ultrasound guided percutaneous liver biopsy at Samsung Medical Center Track bleeding after biopsy Persistent track bleeding even after conservative management Consent to this study Exclusion Criteria: Not consent to this study <20 years old or >=80 years old Contraindication to radiofrequency ablation Radiofrequency ablation for track bleeding is not technically possible. Unstable vital signs

Ages Eligible for Study
-----------------
Minimum Age: 20 Years
Maximum Age: 79 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Radiofrequency ablation group<br>hemostasis using radiofrequency ablation for track bleeding | Procedure: radiofrequency ablation<br>* Under the ultrasound guidance, the electrode is inserted into the bleeding focus of the liver and the bleeding focus is ablated.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| hemostasis rate | success rate of hemostasis using radiofrequency ablation on CT taken after radiofrequency ablation | immediately after radiofrequency ablation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| complication rate | complication rate associated with radiofrequency ablation on CT taken after radiofrequency ablation | immediately after radiofrequency ablation | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
liver, track bleeding, radiofrequency ablation