Efficacy of Personal Pharmacogenomic Testing as an Educational Tool in the Pharmacy Curriculum

Study Overview
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Brief Summary
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The purpose of this study is to evaluate the use of personal genomic educational testing (PGET) on student knowledge and clinical skills surrounding pharmacogenomic testing to ensure it is of educational benefit to our student population. Students will be provided the opportunity to opt-in to test their own pharmacogenomic panel while participating in the standard curriculum. Students will have the option of using their own reports or dummy reports during classroom activities. Our hypothesis is that those students who have their own pharmacogenomics tested will show better overall performance.

Official Title
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Efficacy of Personal Pharmacogenomic Testing as an Educational Tool in the Pharmacy Curriculum

Conditions
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Healthy

Intervention / Treatment
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* Genetic: Personal genomic educational testing (PGET)
* Genetic: No personal genomic educational testing (NPGET)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Willingness to provide informed consent for participation in the study Enrolled in 3rd year Doctor of Pharmacy course Exclusion Criteria: Unwilling or unable to provide consent for participation
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: We investigated the effect of PGET on student knowledge, comfort, and attitudes related to pharmacogenomics (PGx) in a non-blinded, randomized controlled trial. Consenting participants were randomized to receive PGET or no PGET (NPGET) during four subsequent years of a PGx course.
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Personal genomic educational testing (PGET)<br>PGET group participants received their own pharmacogenomic testing results prior to the course modules covering material tested in the knowledge assessment | Genetic: Personal genomic educational testing (PGET)<br>* PGET consisted of a panel of pharmacogenomic variants<br>|
| Placebo Comparator: No personal genomic educational testing (NPGET)<br>No PGET (NPGET) group participants did not receive their own pharmacogenomic testing results until after study completion. | Genetic: No personal genomic educational testing (NPGET)<br>* Lack of pharmacogenomic testing<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Pharmacogenomics Knowledge Assessment | Improvement in performance on a knowledge assessment including eleven questions | 8-12 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Self Assessment Questionnaire | Improvement in Likert Scale Responses for 27 questions (scale of 1[worst] to 6[best]) | 8-12 weeks |