Prediction Rules for Low Level Laser on Burn Wounds

Study Overview
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Brief Summary
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The purpose of this study is to investigate whether patients' age, total burned surface area, wound stage and wound depth determine wound healing response to low level laser therapy in burn patients

Detailed Description
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It will be hypothesized that Age may significantly affect burn wound healing's response to low level laser therapy. TBSA may significantly affect burn wound healing's response to low level laser therapy. Depth of wound may significantly affect burn wound healing's response to low level laser therapy. Wound healing stage may significantly affect burn wound healing's response to low level laser therapy. There will be only one intervention group. The duration of the study will be 6 weeks divided to 18 sessions (three sessions per week). Sixty patients (male and female) will be recruited from the burn units. Low level laser therapy will be performed for 30 min 3 times per week for 8 weeks on the wound area. Wound area was irradiated by a red 655 nm light, 150 mW, 2 J/cm2 at the bed of the wound.

Official Title
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DEVELOPMENT OF A CLINICAL PREDICTION RULES TO IDENTIFY EFFICACY OF LOW LEVEL LASER ON BURN WOUND HEALING

Conditions
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Burn Wound, Clinical Prediction Rules

Intervention / Treatment
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* Device: low level laser therapy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Partial thickness Burn wound depth. Age ranges from 20-50 years. TBSA more than 15% Sufficient understanding to perform the test Exclusion Criteria: Diabetic patients. Burn wound with skin graft Infected wounds Patients receiving immunosuppressive drugs. Patients receiving irradiation or chemotherapy. Chronic circulatory diseases Severe associated injury with burn. Associated co-morbidities, such as neurological diseases, malnutrition, and other inﬂammatory and/or infectious diseases.

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Interventional Model Description: 60 adult of both sexes will participate in this study selected from burn unit of AHMED ORABI hospital, Their ages range from 10 to 50 years, TBSA more than 15%, partial thickness burn depth.
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: burn wound receiving low level laser therapy<br> | Device: low level laser therapy<br>* Low level laser therapy will be performed for 30 min 3 times per week for 8 weeks on the wound area. Wound area was irradiated by a red 655 nm light, 150 mW, 2 J/cm2 at the bed of the wound.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| reduced wound surface area | measure of wound surface area using manual tracing method before and after application of treatment | maximum of 6 weeks |