Cardiac Operation Under Totally Endoscope and Cardiopulmonary Bypass (CPB)

Study Overview
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Brief Summary
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Conventional cardiac operations are performed with median sternotomy, which is related to great wound, morbidities, longer duration in hospital and most significantly, cosmetic problems. The investigators invested a new minimally invasive cardiac operation method totally under video-endoscope and peripheral cardiopulmonary bypass. The investigators' hypothesis is that this new minimally method could provide better cosmetic effects to the patients, and also relate to shorter postoperative hospital stay and better recovery.

Official Title
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Cardiac Operation Under Totally Endoscope and Cardiopulmonary Bypass, a Single Center's Experience

Conditions
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Congenital Heart Defects, Heart Valve Diseases

Intervention / Treatment
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* Procedure: cardiac operation with totally endoscopic method


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: congenital heart defects or heart valve diseases require surgical correction Exclusion Criteria: Body weight < 10kg committed with complex congenital heart defect anticipated to perform aortic valve repair or replacement anticipated to perform aorta repair or replacement committed with Femoral vessel diseases unable to perform femoral cannulation refuse to perform totally thoracoscope minimally invasive surgery

Ages Eligible for Study
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Minimum Age: 2 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Totally endoscopic cardiac operation<br>Patients with cardiac diseases undergo cardiac operations with totally endoscopic and cardiopulmonary bypass | Procedure: cardiac operation with totally endoscopic method<br>* Cardiac operations are performed with three keyholes in the right chest wall. Video images are obtained by digital thoracoscope through one hole. Intracardiac lesions are accessed with surgical instruments and repaired through the other two holes. Cardiopulmonary bypass is set up with femoral cannulations. Moderate system hypothermic is applied for the operation. Cardiac arrest is achieved with ascending aorta clamp and cardioplegia solution delivery through aortic root cannulation. After the intracardiac lesions are repaired, aortic clamp is removed, and the heart is reperfused to restore its spontaneous rhythm. After the patients are rewarmed to normal temperature, CPB is discontinued. Femoral cannulations are removed, and surgical wounds are closed.<br>* Other names: thoracoscopic cardiac surgery;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| all cause mortality |  | one year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| all cause morbidity |  | one year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Surgical Procedures, Cardiac, Minimally Invasive Surgical Procedures, Thoracoscopes, Cardiopulmonary Bypass