Muscle Oxygenation in Treadmill and Cycle Ergometer Exercise

Study Overview
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Brief Summary
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The study will be conducted on healthy young adults. Hemodynamic effects such as heart rate, blood pressure, oxygen saturation (SpO2), including muscle oxygenation, will be compared in treadmill and bicycle exercises.

Detailed Description
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In recent studies, sensor systems that measure the oxygen level in muscle tissue at the microvascular level have been developed. These devices working with Near Infrared Spectroscopy (NIRS, 630-850 nm) method; It provides measurements of muscle oxygenation level at rest and during exercise. It is known that significant changes in vastus lateralis oxygenation levels measured by the NIRS method are associated with various factors such as exercise intensity, exercise profile and training. The aim of this study is to measure the oxygenation level of the vastus lateralis muscle during the exercises performed on the treadmill and bicycle ergometer, and thus to reveal the effect of using different ergometers on fatigue and sportive performance. Muscle oxygen levels will be measured and evaluated before, during and after exertion. In addition, blood pressure (BP), oxygen saturation (SpO2), dyspnea and fatigue parameters will be recorded and evaluated. If undesirable symptoms are observed during our study, the exercise will be terminated. Within the scope of the project, the acute effect will be examined with the measurements made with the Moxy device on the vastus lateralis muscle during the treadmill and bicycle ergonometer.

Official Title
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Comparison of Oxygenation of the Vastus Lateralis Muscle During Cycling and Treadmill Exercises

Conditions
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Muscle Oxygenation, Treadmill

Intervention / Treatment
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* Other: Questionnare
* Device: Moxy Muscle Oxygen Monitor


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Volunteering to participate in the study No known disease Be between the ages of 18-25 Exclusion Criteria: Having cardiopulmonary disease, Have had lower extremity muscle or joint injuries Having an orthopedic/neurological disorder Smoking and alcohol use, Have suffered a lower extremity muscle or joint injury, Having an orthopedic/neurological disorder, Uncontrollable asthma, PaO2< 50 mmHg, PaCO2> 70mmHg, Individuals with a resting systolic blood pressure of 200 mmHg

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 25 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Screening
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Treadmill Group<br>Hemodynamic effects such as heart rate, blood pressure, oxygen saturation (SpO2), dyspnea and fatigue including muscle oxygenation, will be compared during treadmill exercises. | Other: Questionnare<br>* Measurement of Dyspnea and Fatigue during submaximal exercise with The Modified Borg Scale (MBS).<br>Device: Moxy Muscle Oxygen Monitor<br>* Measurement of muscle oxygenation with Moxy Muscle Oxygen Monitor.<br>|
| Experimental: Cycle Group<br>Hemodynamic effects such as heart rate, blood pressure, oxygen saturation (SpO2), dyspnea and fatigue including muscle oxygenation, will be compared during cycling exercises. | Other: Questionnare<br>* Measurement of Dyspnea and Fatigue during submaximal exercise with The Modified Borg Scale (MBS).<br>Device: Moxy Muscle Oxygen Monitor<br>* Measurement of muscle oxygenation with Moxy Muscle Oxygen Monitor.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Measurement of Patient-Reported Dyspnea and Fatigue | Measurement of dyspnea during submaximal exercise with The Modified Borg Dyspnea Scale (MBS). | Baseline | 
| Measurement of Muscle Oxygenation | Measurement of muscle oxygenation with Moxy Monitor. | Baseline | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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muscle oxygenation, treadmill, cycle, moxy, exercise