Contingency Management for Smoking in Substance Abusers

Study Overview
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Brief Summary
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Patients (N=102) who meet diagnostic criteria for alcohol, cocaine, marijuana, or opiate abuse or dependence will meet with research staff on two days for quit preparation sessions (2 per day). These sessions include testing a breath sample for evidence of smoking twice each day (separated by at least 5 hours), counseling based on Public Health Service (PHS) guidelines for quitting smoking during the second session each day, and setting a quit date. After these sessions, participants will be randomly assigned to one of two 4-week conditions: (a) standard care or (b) standard care plus prize CM for smoking abstinence with the opportunity to win prizes for submitting samples that meet smoking abstinence criteria (e.g., CO ≤ 6ppm; cotinine ≤ 30ng/mL). Nicotine withdrawal and related measures will be assessed throughout the intervention. Follow-up data will be collected through 6-months post-quit date.

Official Title
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Contingency Management for Smoking in Substance Abusers

Conditions
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Cigarette Smoking

Intervention / Treatment
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* Behavioral: Contingency Management
* Behavioral: Brief smoking cessation counseling


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: current alcohol, cocaine, marijuana, or opiate abuse or dependence smoke ≥ 10 cigarettes per day expired CO > 8 ppm self-reported interest in quitting smoking, ≥ 18 years old willing to provide names, addresses and phone numbers of individuals to assist in locating the participant for follow-up evaluations, English speaking Exclusion Criteria: currently receiving behavioral therapy or pharmacotherapy for smoking plan to use pharmacotherapy in this quit attempt serious, uncontrolled psychiatric illness (e.g., acute schizophrenia, suicide risk) cognitive impairment in recovery for pathological gambling

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: A<br>Brief counseling based on public health service guidelines. | Behavioral: Brief smoking cessation counseling<br>* For 4 weeks starting on the quit date, daily brief (about 5 minutes) counseling based on public health service guidelines for quitting smoking. Expired carbon monoxide tests are conducted twice daily and urinary cotinine tests are conducted once each week.<br>|
| Experimental: B<br>Brief counseling based on public health service guidelines for quitting smoking plus prize-based contingency management | Behavioral: Contingency Management<br>* For 4 weeks starting on the quit date, daily brief (about 5 minutes) counseling based on public health service guidelines for quitting smoking is delivered. Expired carbon monoxide (CO) tests are conducted twice daily and urinary cotinine tests are conducted once each week. Participants earn the opportunity to win prizes for submitting samples that meet smoking abstinence criteria (e.g., CO ≤ 6ppm; cotinine ≤ 30ng/mL).<br>Behavioral: Brief smoking cessation counseling<br>* For 4 weeks starting on the quit date, daily brief (about 5 minutes) counseling based on public health service guidelines for quitting smoking. Expired carbon monoxide tests are conducted twice daily and urinary cotinine tests are conducted once each week.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cigarette smoking abstinence. |  | Daily through the 4-week intervention and at follow-up interviews 1, 2, 3, and 6 months following the quit date. | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Contingency Management, Cigarette Smoking Cessation, Substance Abusers