Lifestyle Intervention and Physical Capacity in Patients With Morbid Obesity

Study Overview
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Brief Summary
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Lifestyle intervention and physical capacity in patients with morbid Obesity (LEICO)

Detailed Description
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It is still uncertainty about which is the most effective lifestyle treatment to reducing body weight and increased quality of life. Increased physical capacity and muscle mass lead to increased energy expenditure, thus explaining parts of the difference in weight loss achieved after lifestyle treatment. However, literature in this area is limited and need better documentation of how, and to what extent increased physical capacity can affect the effect of lifestyle treatment offered to patients in the health service.

Official Title
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Lifestyle Intervention and Physical Capacity in Patients With Morbid Obesity

Conditions
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Physical Capacity

Intervention / Treatment
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* Other: Lifestyle


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Treatment morbidly obese patients (BMI ≥ 40 kg/m2 or BMI 35 to 39.9 kg/m2 with ≥ 1 co morbidity) attending the Vestfold Hospital Trust. Exclusion Criteria: Uncompensated heart failure Recent myocardial infarction or stroke (<½ years) Severe arrhythmia or heart failure Unstable angina pectoris Renal failure Severe eating disorders Active substance abuse

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 99 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Lifestyle|Lifestyle intervention an effect on weight and physical capacity|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Weight change at 1-year follow up | Can physical capacity before start of a routine medical care have a impact on weight loss at 1-year follow-up. Body weight was measured with patients wearing light clothing and no shoes on Scanvaegt DS-530 (Århus, Denmark) at baseline and after 1-year follow up. Changes from baseline body weight at 1-year follow up. Participants receive interventions as part of routine medical care, and studie the effect of the intervention. | Changes from baseline body weight at 1-year follow up. | 
| Weight change at 12-weeks follow up | Can physical capacity before start of a routine medical care have a impact on weight loss at 12-weeks follow-up. Body weight was measured with patients wearing light clothing and no shoes on Scanvaegt DS-530 (Århus, Denmark) at baseline and after 12-weeks follow up. Changes from baseline body weight at 12-weeks follow up. Participants receive interventions as part of routine medical care, and studie the effect of the intervention. | Changes from baseline body weight at 12-weeks follow up. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Physical capacity changes after 12 weeks as assessed by the maximal oxygen uptake test | Can the mean twelve-week change in physical capacity be associated with weight loss. The maximal oxygen uptake test was performed as an incremental treadmill test on Woodway ELG 55 (Waukesha, Germany) or, for patients with walking restrictions, on an incremental bicycle test (Lode Corival V3, Lode BV, Groningen, Netherlands). Oxygen uptake was registered using the Jaeger oxycon pro ergospirometry test system (Jaeger Oxycon Pro JLAB 5.x, Hoechberg, Germany). Changes from baseline physical capacity at 12-weeks follow up. | Changes from baseline physical capacity at 12-weeks follow up. |