Multicenter Database of Patients With Germ Cell Tumor

Study Overview
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Brief Summary
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Retrospective and prospective cohort of patients with germ cell tumor in treatment.

Detailed Description
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The primary objective of this study is to create a multicenter database in order to characterize epidemiologically and clinicopathologically patients with germ cell tumor and evaluate the prognosis and clinical outcomes during cancer treatment.

Official Title
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Multicenter Database of Patients With Germ Cell Tumor in Order to Characterize Clinicopathologically and to Evaluate Cancer Treatment Outcomes

Conditions
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Neoplasms, Germ Cell and Embryonal

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Male patients with diagnosis of testicular, retroperitoneum or mediastinal primary tumor. Histological confirmation of germ cell tumor or clinical condition based on the elevation of tumor markers (AFP, HCG e/ou DHL) associated to testicular mass or/and retroperitoneal lymphnode enlargement or/and mediastinal mass. Medical records of the disease and treatment Exclusion Criteria: Female patients diagnosed with ovary germ cell tumor Male patients diagnosed with germ cell tumor in other locations.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Brazilian multicenter database in order to collect and analyze data from diagnosis and treatment of patients with germ cell tumor |  | From 2000 to 2025 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Description of demographic characteristics of testicular germ cell tumor patients in Brazil |  | From 2000 to 2025 | 
| The clinical and pathological characteristics of testicular germ cell tumor patients in Brazil. |  | From 2000 to 2025 | 
| Treatment according to staging and relapse of patients diagnosed with testicular germ cell tumor in Brazil |  | From 2000 to 2025 | 
| Disease free survival of patients diagnosed with germ cell tumor stage 1. |  | From 2000 to 2025 | 
| Overall survival of patients diagnosed with germ cell tumor stage 1. |  | From 2000 to 2025 | 
| Disease free survival of patients diagnosed with germ cell tumor stages 2 and 3. |  | From 2000 to 2025 | 
| Overall survival of patients diagnosed with germ cell tumor stages 2 and 3. |  | From 2000 to 2025 | 
| International prognostic factors in patients with advanced germ cell tumor (stages 2 and 3) stablished by the International Germ Cell Cancer Collaborative Group in brazilian patients. |  | From 2000 to 2025 | 
| Treatment outcome in different populations: in patients with brain metastasis, patients with germinative tumor extragonodal, surgery outcome in patients with nonseminomous tumor and ressection of residual lesion after chemotherapy |  | From 2000 to 2025 | 
| Disease free survival of patients diagnosed with disease relapse after first line chemotherapy |  | From 2000 to 2025 | 
| Overall survival of patients diagnosed with disease relapse after first line chemotherapy |  | From 2000 to 2025 | 
| Prognostic model after first line treatment failure with cisplatin, stablished by the International Prognostic Factors Study Group in brazilian patients. |  | From 2000 to 2025 |