Recruitment Maneuver Using Lung Ultrasound in Trauma Patients

Study Overview
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Brief Summary
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In trauma patients, the incidence of pulmonary contusion is frequent. Recruit maneuver using lung ultrasound could be improve oxygenation in trauma populatioin, howevere, there is no previous study. The aim of this study is evaluation of the efficacy of lung recruitment using ultrasound in perioperative period in trauma patients.

Detailed Description
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In trauma patients, the incidence of pulmonary contusion is 17-75%. Pulmonary contusioin leads to atelectasis, lung consolidatioin. Finally it could results acute respiratory distress syndrome. Lung ultrasound is non-invasive and available in anytime even during surgery. Previous studies showed recruitment maneuver using ultrasound improved postoperative oxygenation in pediatric cardiac surgery. In adults, recruitment maneuver not using ultrasound improved oxygenation after cardiopulmonary bypass. There is no study in adult trauma population. The aim of this study is evaluation of the efficacy of lung recruitment using ultrasound in perioperative period in trauma patients.

Official Title
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Evaluation of Efficacy of Recruitment Maneuver Using Lung Ultrasound in Trauma Patients

Conditions
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Recruitment, Trauma

Intervention / Treatment
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* Diagnostic Test: Ultrasound


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Who need surgery under general anesthesia due to trauma The position of the surgery is supine Exclusion Criteria: Who has been ventilator care before the surgery Thoracic surgery Who had cardiopulmonary resuscitation Who has acute respiratory distress syndrome

Ages Eligible for Study
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Minimum Age: 19 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Randomized prospective trial st group is sono group using lung ultrasound nd group is control group
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: sono group<br>Evaluate the participant's lung condition using ultrasound and do recruitment maneuver if it is necessary | Diagnostic Test: Ultrasound<br>* Evaluate participant's lung condition using ultrasound. Using lung ultrasound scoring, more than 1 point needs recruitment maneuver<br>|
| No Intervention: control group<br>If participants need recruitment maneuver (decreasing saturation, peak airway pressure > 35 mmHg) by clinical judgement, do recruitment maneuver not using lung ultrasound | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| arterial oxygen partial pressure / fractional inspired oxygen ratio at end of surgery | = P /F ratio; Smaller value respresents poor outcome Using arterial blood gas analysis the difference between baseline (immediate after intubation) and end of surgery : If P/F ratio difference is improved compared to baseline, it means recruitment maneuver is effective | 2 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Lung ultrasound score | Using lung ultrasound, evaluate lung condition in both group at end of surgery Scoring using lung ultrasound scoring Scoring range: 0, normal; 1, small loss of aeration; 2, moderate loss of aeration; 4, severe loss of aeration | 2 hours | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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recruitment, ultrasound, trauma, pulmonary contusion