Post - Hospital Syndrome: Profile of Functional Status by Malnutrition

Study Overview
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Brief Summary
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Malnutrition is common problem in hospitalized geriatrics at discharge. Malnutrition is a high risk for functional limitations, impaired muscle strength and reduced quality of life.

Detailed Description
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The majority of geriatric hospitalized patients are at high risk for malnutrition at discharge, which has negative impact on post-hospital outcomes. In a cross-sectional analysis in malnourished, geriatric patients we will evaluate frailty-status and functional status using objective and subjective methods at hospital discharge. Moreover, we will investigate the association between nutritional Status and frailty, sarcopenia, quality of life and fatigue.

Official Title
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Post-Hospital Syndrome: Evaluation of Functional Status in Malnourished, Geriatric Patients at Hospital Discharge

Conditions
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Malnutrition, Sarcopenia

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age ≥ 60 years Informed written consent Existing or risk of malnutrition Normal cognitive status according to Mini-Mental State Examination (MMSE ≥ 24 points) Life expectancy of > 3 months according to treating doctor Exclusion Criteria: Age < 60 years Lack of informed written consent No risk of malnutrition Low cognitive status according to Mini-Mental State Examination (MMSE < 24 points) Life expectancy of < 3 months according to treating doctor

Ages Eligible for Study
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Minimum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Malnourished<br>malnourished, geriatrics patients at hospital discharge | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Functional Parameter: gait speed | gait analysis | Baseline (hospital discharge) | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Functional Parameter: timed up & go (TUG) time | timed up & go (TUG) test | Baseline (hospital discharge) | 
| Functional Parameter: stair climbing time | stair climbing test | Baseline (hospital discharge) | 
| Functional Parameter: Peak expiratory flow rate | peak flow meters scale | Baseline (hospital discharge) | 
| Strength Parameter: Hand grip strength | Hand grip strength measurement | Baseline (hospital discharge) | 
| Strength Parameter: Knee extension strength | Knee extension strength measurement | Baseline (hospital discharge) | 
| Index of quality of life | validated questionnaire | Baseline (hospital discharge) | 
| Body composition | bioelectric impedance Analysis | Baseline (hospital discharge) | 
| Frailty-Status | Fried criteria | Baseline (hospital discharge) | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Malnutrition, Disease-related malnutrition, Frailty, Sarcopenia, Hospital discharge, Geriatrics