Whipple Procedure: A 5-year Clinical Experience in Tertiary Care Center

Study Overview
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Brief Summary
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The study was conducted in tertiary care hospital of Lahore. Patient undergoing Whipple procedure were studied by compiling demographic details of the patients, common presenting symptoms, various indications for Whipple's procedure, the cofactors which affect the procedures outcome and morbidity and mortality of the patients.

Detailed Description
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This study was performed by collecting data through predesigned questionnaire about patients undergoing Whipple's procedure from operation theatres and medical record section. Those patients, whose tumor was unresectable and undergone palliative surgical procedures were excluded from the study.

Official Title
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Whipple Procedure: A 5-year Clinical Experience in Tertiary Care Center

Conditions
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Whipple Procedure

Intervention / Treatment
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* Procedure: Whipple Procedure


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients of both sexes with age ranging from 20 years to 70 years patients with pancreatic tumors patients with adequate cardiorespiratory reserves to be fit for prolong general anesthesia Exclusion Criteria: unresectable tumors unfit for surgery

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Interventional Model Description: Patients undergoing Whipple procedure due to pancreatic tumor were included in the study
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: Whipple Procedure|Patients underwent Whipple procedure for pancreatic tumors. The procedure commenced with rooftop incision. then layers of abdomen dissected to reach the peritoneum. Then Duodenum dissected out along with pancreas and common bile duct. After rescetion of these structures the anatomy of the tract restored with three anastomosis namely pancreaticojejunostomy, gastrojejunostomy and choledochojejunostomy/hepaticojejunostomy.|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Percentage of patients developing pancreatic fistula | Percentage of patients developing pancreatic fistula (pancreatic juice collected in drain rich in amylase) after Whipple procedure Enteric leak postoperative complications like pancreatic fistula, anastomotic leakage, hemorrhage, wound infection,mortality | 4 weeks | 
| Percentage of patients developing hemorrhage | Percentage of patients developing hemorrhage after Whipple procedure | 2 weeks | 
| Percentage of patients developing wound infection | Percentage of patients developing wound infection after Whipple procedure | 4 weeks | 
| Mortality rate | Mortality of patients undergoing Whipple surgery | 6 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Whipple procedure, pancreatic carcinoma, biliary stenting,