Evaluation of the Prevalence and Risk Factors for Patients With Peri-implant Disease：a Retrospective Study

Study Overview
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Brief Summary
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To investigate the patient-related risk factors for peri-implant disease in partially edentulous patients rehabilitated with implants supported crown or bridge so as to provide evidence for clinical prevention and control.

Detailed Description
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Objective: To investigate the patient-related risk factors for peri-implant disease in partially edentulous patients rehabilitated with implants supported crown or bridge so as to provide evidence for clinical prevention and control. Methods:A total of 131 patients will enroll in the study. Univariate and multivariate logistic regression analysis is used to determine the patient factors associated with peri-implant disease. The variables include age, gender, smoking and alcohol consumption, presence of diabetes, cardiovascular disease, osteoporosis, bruxism, bleeding upon brushing, reason for extraction, oral hygiene and periodontal status.

Official Title
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The Prevalence and Risk Factors for Patients With Peri-implant Disease：a Retrospective Study

Conditions
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Jaw, Edentulous, Partially

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients implanted at least one implant and restored with implant-supported fixed partial dentures and single crowns. The implant-supported fixed partial dentures and single crowns were in function at least one year. Exclusion Criteria: Jaw radiotherapy treatment before and after implanting. Patients who have bruxism, xerostomia or the adjacent teeth periapical periodontitis. Patients who suffered with oral mucosa disease,or aggressive periodontitis or jaw defect. Patients who suffered with mental and psychological disease will influence their oral health normal maintenance.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| no peri-implant disease<br>The subjects who did not suffer from peri-implant disease. | |
| peri-implant disease<br>The subjects who suffered from peri-implant disease. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Survival of implants | Time from the surgical placement of implants until the first return visit（at least one year after restoration） | at the first return visit（at least one year after restoration） | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Gingival Bleeding on Probing | Gingival bleeding on probing (BOP) using the modified sulcus bleeding index for implants. Scale equals 0 = No bleeding when periodontal probe is passed along the gingival margin;1 = Isolated bleeding spots visible;2 = Blood forms a confluent red line on the gingival margin;3 = Heavy or profuse bleeding. | at the first return visit（at least one year after restoration） | 
| Pocket depths | Pocket depths measured around implants in millimeter (mm) | at the first return visit（at least one year after restoration） | 
| Marginal bone loss | Time from the surgical placement of implants until the first return visit（at least one year after restoration） | at the first return visit（at least one year after restoration） | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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peri-implant disease; risk factors; prevalence