The Efficacy of a 6-point Transscleral Suture Fixation of a 3-looped Haptics PC-IOL Implantation Through Scleral Pockets for Surgical Management for Microspherophakia

Study Overview
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Brief Summary
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By comparing the preoperative data and postoperative data of 9 patients of microspherophakia, we concluded that the 6-point transscleral suture fixation of a 3-looped haptics posterior chamber intraocular lens (PC-IOL) through scleral pockets was a feasible method of PC-IOL implantation in the surgical treatment of microspherophakia.

Official Title
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The Efficacy of a 6-point Transscleral Suture Fixation of a 3-looped Haptics PC-IOL Implantation Through Scleral Pockets for Surgical Management for Microspherophakia

Conditions
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Microspherophakia

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Microspherophakia was diagnosed and lens diameter<9mm; The lens subluxation was beyond the range of one quadrant and glasses cannot correct the vision; Lens dislocated into the anterior chamber; Lens dislocation caused elevated intraocular pressure (IOP); The lens contacted the corneal endothelium; Cataract; Corneal endothelial cell density>1000/mm2; The fundus was normal without retinal detachment, severe macular disease and optic nerve atrophy； There was possible improvement in postoperative visual acuity measured by retinometer. Exclusion Criteria: The lens is centered and the position of the lens is stable; Glasses can correct the vision obviously; The reason for the elevated IOP was independent with the lens; A high possibility of corneal decompensation after surgery; Fundus function was poor and it is not expected to improve the vision after surgery; Combined with other ocular diseases which were not suitable for IOL implantation; Combined with a systemic disease that the patient cannot tolerate the surgery.

Ages Eligible for Study
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Minimum Age: 10 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Microspherophakia<br>This is a non-interventional study(NIS). All the patients diagnosed as microspherophakia are included in the study and recieved intraocular lens implantation | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual function | Best corrected visual acuity (BCVA) measured using a decimal chart | 6 month postoperation | 
| Visual function | uncorrected distance visual acuity (UDVA) measured using a decimal chart | 6 month postoperation | 
| Intraocular pressure | intraocular pressure measured using non-contact tonometer | 6 month postoperation | 
| PCIOL tilt degree | PCIOL tilt degree measured using Ultrasound biomicroscope | 6 month postoperation | 
| PCIOL decentration distance | PCIOL decentration distance measured using Ultrasound biomicroscope | 6 month postoperation | 
| Endothelial cell density | Endothelial cell density was measured by specular microscopy | 6 month postoperation | 
| Anterior chamber depth | Anterior chamber depth measured using Ultrasound biomicroscope | 6 month postoperation |