Functional Trunk Training in Ataxia Patients

Study Overview
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Brief Summary
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The study is to examine the effect of functional trunk training on trunk control and upper extremity functions in patients with autosomal recessive ataxia.

Detailed Description
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Hereditary ataxias are a group of genetic diseases characterized by slow progressive gait disturbance. In addition, coordination disorders can be seen in extremities, speech and eye movements. Atrophy is common in the cerebellum. Friedreich's ataxia, ataxia telangiectasia, ataxia with vitamin E deficiency, infantile-onset spinocerebellar atrophy and Marinesco-Sjögren syndrome are autosomal recessive hereditary ataxias. The constant main sign of autosomal recessive ataxia is progressive ataxia. The trunk has an important role on dynamic stabilization for postural reactions and limb movements. A good trunk support enables movements in other parts of the body to occur more regularly. Trunk stabilization is important to support upper and lower extremity movements, to meet the loads, and to protect the spinal cord. The relationship between upper extremity function, daily living activities and trunk functions has been emphasized in many studies but comparative studies about the rehabilitation were very less. This study is to evaluate the effect o functional trunk training in patients with autosomal recessive ataxia.

Official Title
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The Effect of Functional Trunk Training on Trunk Control and Upper Extremity Functions in Hereditary Ataxia Patients With Autosomal Recessive

Conditions
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Ataxia, Spinocerebellar, Ataxias, Hereditary

Intervention / Treatment
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* Other: Functional training
* Other: Routine training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Without any communication impairment (seeing, hearing, hearing), Have not had surgery for the upper and lower extremities in the last 6 months, Between the ages of 5 and 18, The mental level determined by the pediatrician is sufficient, Exclusion Criteria: Patients who want to leave the study at any stage of the study Patients who do not attend regular training

Ages Eligible for Study
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Minimum Age: 5 Years
Maximum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Participants were divided in two groups. Two groups will get two different intervention.
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Control<br>Routine training; mat exercises and perturbation training | Other: Routine training<br>* The therapy program was planned for 8 weeks and the sessions were performed in 45 minutes (min) for 3 days a week. The strengthening exercises were applied on the mat (3x10 for the first 4 weeks and 3x15 repetition for the last 4 weeks). Eyes open-closed perturbation training was performed for trunk control in sitting and standing positions (10 min.).<br>|
| Experimental: Study<br>Trunk training; Functional training, mat exercises and perturbation training | Other: Functional training<br>* The therapy program was planned for 8 weeks and the sessions were performed in 45 minutes (min) for 3 days a week. The functional reach (forward-lateral-cross), trunk rotation exercises were performed in the sitting positions.(25min) Facilitation of trunk extension and elongation in the prone position (10 min). Thoracic mobilization on exercise ball (10min).<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The Functional Independence | The Functional Independence Scale for Children (WeeFIM) was used determine to independence level. | through of te study, average 8 weeks | 
| Trunk impairment | The Trunk Disorder Scale (TIS) was used to assess static and dynamic sitting balance and trunk coordination | through of te study, average 8 weeks | 
| The severity of ataxia | The International Ataxia Rating Scale (ICARS) was used to determine the severity | through of te study, average 8 weeks | 
| The quality of life | The Children's Quality of Life Scale (PedsQL) was used determine to quality of life level. | through of te study, average 8 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Upper extremity functional performance | The 9-Hole Peg test was used to evaluate upper extremity performance | through of te study, average 8 weeks | 
| Functional Reach Test | Functional Reach Test was used determine to dynamic trunk balance | through of te study, average 8 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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ataxia,rehabilitation,trunk,disabilities