Comparison of Erector Spinae Plane Block and Intravenous Analgesic in Nefrectomy

Study Overview
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Brief Summary
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The efficacy of erector spinae plane block versus intravenous analgesics compared relate to the morphine consumptions

Detailed Description
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Patients undergoing elective nefrectomy were enrolled. Patients divided into two groups with a sealed envelope technique to ESP+ pca morphine group or iv analgesic + pca morphine group. All patients will premedicated. then esp will applied to one group before surgery at the preoperative care unit by the same anesthesiologist. The other group will receive intravenous tramadol 1 mg/kg + NSAID 1 ampule + parol 10 mg/ kg + ondansetron 4 mg bolus. İntravenous morphine pca with a concentration of 0.5 mg/cc were applied. And administered 1 mg boluses every 15 minutes lock time and 4 hour limit as 4 mg arranged. An anesthesia nurse who is responsible of all pcas' in the hospital was recorded the variables of these patients in the service

Official Title
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Erector Spinae Plane Block for Nefrectomy

Conditions
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Regional Anesthesia Morbidity, Nephrectomy

Intervention / Treatment
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* Procedure: erector spinea plane block administered preoperative open nephrectomy
* Procedure: intravenous analgesic ( 1 mg/kg tramadol + non-steroid antiinflamatuar paracetamol )drug + 10 mg.kg


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria:18-65 years age ASA I-II undergoing elective nephrectomy Exclusion Criteria:- ASA>3 heart disease pregnancy lung disease scoliosis bleeding disorder infection at the manipulation side

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: postoperative opiod (morphine) consumption<br>patient-controlled analgesia (15 minutes. lock time, 2 ml bolus= total 1 mg morphine intravenously, limited to maximum 4 bolus / per hour ) | Procedure: erector spinea plane block administered preoperative open nephrectomy<br>* erector spinae plane block applied in this group before open nephrectomy<br>Procedure: intravenous analgesic ( 1 mg/kg tramadol + non-steroid antiinflamatuar paracetamol )drug + 10 mg.kg<br>* intarvenous analgesic administered in this group for analgesia end of the open nephrectomy<br>|
| Active Comparator: peroperative continuous opioid (remifentanil) consumption<br>continuous remifentanil infusion was given during the whole procedure | Procedure: erector spinea plane block administered preoperative open nephrectomy<br>* erector spinae plane block applied in this group before open nephrectomy<br>Procedure: intravenous analgesic ( 1 mg/kg tramadol + non-steroid antiinflamatuar paracetamol )drug + 10 mg.kg<br>* intarvenous analgesic administered in this group for analgesia end of the open nephrectomy<br>|
| Active Comparator: postoperative numerated rating scale<br>at the 1, 3, 6, 12 and 24 th hour postoperatively - numerated rating scale score was evaluated and recoded as 0= no pain (better), 10: unbearable pain (worse) | Procedure: erector spinea plane block administered preoperative open nephrectomy<br>* erector spinae plane block applied in this group before open nephrectomy<br>Procedure: intravenous analgesic ( 1 mg/kg tramadol + non-steroid antiinflamatuar paracetamol )drug + 10 mg.kg<br>* intarvenous analgesic administered in this group for analgesia end of the open nephrectomy<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative intravenous morphine patient controlled analgesia consumption | morphine consumptions were recorded till 24 th hour postoperatively | during postoperatively | 
| Peroperative remifentanyl consumption | Amount of Remifentanyl consumption recorded | Peroperatively | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual analog rating scores | pain scores were recorded during surgery | during postoperative surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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nefrectomy, erector spinea plane block