Perception of the Doctor/Patient Relationship, Disease and Treatment Among Physicians and Their Patients Treated With Systemic Therapy for Hepatocellular Carcinoma PERCEPTION1

Study Overview
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Brief Summary
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atients with cancer face difficult choices that require balancing competing priorities such as survival, functional capacity and symptom relief. Most patients with advanced cancer (>80%) expect their sensitive discussions with physicians about prognosis and treatment choices, in order to be involved in the decision making process. Nevertheless, this kind of discussion is frequently lacking. Consequently, patients often have a biased view of their own prognosis such as an underestimation of disease severity, or unrealistic expectations for cure. Patients with advanced hepatocellular carcinoma (HCC) may be treated with systemic therapies which may prolong survival, but are not curative. Patients with advanced HCC often report expectations for survival and treatment-related side-effects that differ from their treating physician. Accordingly, communication on prognostic and treatment choices is essential to obtain an accurate understanding of the disease that allows patients to make informed decisions. To the best of our knowledge, a thorough evaluation of the physician-patient communication quality has never been performed in advanced HCC patients. The aim of our study, is to assess the perception of the expected prognosis, the treatment side-effects; by the patient and by his investigator during the first consultation before the initiation

Detailed Description
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atients with cancer face difficult choices that require balancing competing priorities such as survival, functional capacity and symptom relief. Most patients with advanced cancer (>80%) expect their sensitive discussions with physicians about prognosis and treatment choices, in order to be involved in the decision making process. Nevertheless, this kind of discussion is frequently lacking. Consequently, patients often have a biased view of their own prognosis such as an underestimation of disease severity, or unrealistic expectations for cure. Patients with advanced hepatocellular carcinoma (HCC) may be treated with systemic therapies which may prolong survival, but are not curative. Patients with advanced HCC often report expectations for survival and treatment-related side-effects that differ from their treating physician. Accordingly, communication on prognostic and treatment choices is essential to obtain an accurate understanding of the disease that allows patients to make informed decisions. To the best of our knowledge, a thorough evaluation of the physician-patient communication quality has never been performed in advanced HCC patients. The aim of our study, is to assess the perception of the expected prognosis, the treatment side-effects; by the patient and by his investigator during the first consultation before the initiation

Official Title
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Perception of the Doctor/Patient Relationship, Disease and Treatment Among Physicians and Their Patients Treated With Systemic Therapy for Hepatocellular Carcinoma

Conditions
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Hepatocellular Carcinoma

Intervention / Treatment
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* Other: Hospitalized patient with advanced hepatocellular carcinoma receiving systemic therapy.


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patient over 18 years of age Patient informed and not objecting to participate in the study Patient with advanced hepatocellular carcinoma. Patient treated with systemic therapy Exclusion Criteria: Locoregional treatment combined with systemic treatment Pregnancy in progress Candidate for surgery or locoregional therapy Patient with state medical aid (AME)

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 90 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Hospitalized patient with advanced hepatocellular carcinoma receiving systemic therapy.|Administation of two surveys to included patients, about the perception of the disease and the expectations related to the treatment. The physician will be asked to complete a survey on his or her perception of the prognosis and information received by the patient.|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Evaluate the concordance between the patient's perception of his prognosis and treatment side effects with the one of his treating physician. | Use of survey completed by the patient and the doctors to assess the primary endpoint | 12months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Compare the patient's expectations for the aforementioned items to those of his physician and the degree of concordance between them. | Use of survey completed by the patient and the doctors to assess the primary endpoint | 12 months | 
| Evaluation of patient satisfaction with the information received during the consultation | Use of survey completed by the patient and the doctors to assess the primary endpoint | 12 months | 
| Assessment of patient-reported symptoms of anxiety and depression | Use of survey completed by the patient and the doctors to assess the primary endpoint | 12 months | 
| Evaluate the association between individual prognosis expectation (patient and physician) and data from the available literature. | Use of survey completed by the patient and the doctors to assess the primary endpoint | 12 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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hepatocellular carcinoma, systemic treatment