Exercise as a Life-long Medicine in Patients With Coronary Artery Disease

Study Overview
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Brief Summary
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Exercise training is a core component in cardiac rehabilitation. Exercise adherence is, however, low after rehabilitation and the transition from supervised to unsupervised exercise is problematic for many patients with coronary artery disease. Therefore, it is important to provide extended services to improve exercise adherence and healthy lifestyle changes. The aim of this study is to assess the effect of a time-limited intervention following out-patient cardiac rehabilitation on exercise adherence and cardiovascular risk reduction.

Official Title
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How to Enhance Physical Activity After Cardiac Rehabilitation? A Randomised Controlled Study Comparing Two Follow-up Training Exercise Programs

Conditions
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Cardiovascular Diseases, Myocardial Infarction, Angina (Stable)

Intervention / Treatment
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* Behavioral: high-intensity exercise training
* Behavioral: web-based follow-up program
* Behavioral: usual care


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: myocardial infarction, stable angina, heart surgery finished phase 2 cardiac rehabilitation clinically stable able to communicate in Norwegian able to do a maximal treadmill test Exclusion Criteria: unstable angina serious cardiac arrhythmia serious heart valve insufficiency heart failure any contraindication for high intensity exercise training participation in other exercise study pregnancy cognitive impairment drug abuse

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: high-intensity exercise<br>community-based group program: weekly supervised high-intensity exercise training during 8 weeks, followed by group counselling every third month for 12 months | Behavioral: high-intensity exercise training<br> <br> |
| Active Comparator: web-based follow-up<br>web-based follow-up program: home-based group will be followed up by mail and telephone calls the first 8 weeks, then every third month for 12 months | Behavioral: web-based follow-up program<br> <br> |
| Other: control<br>control group will receive usual care: information about recommended physical activity and healthy lifestyle | Behavioral: usual care<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| change in peak oxygen uptake | measured during exercise on treadmill (MetaMax Cortex/Innocor) | 2 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| physical activity | assessed by accelerometer SenseWear Armband Pro | 2 years | 
| quality of life | assessed by MacNew Health-related quality of life questionnaire | 2 years | 
| depression | assessed by Hospital anxiety and depression scale (HAD) | 2 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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exercise therapy, rehabilitation