The Effect of Eyelid Surgery on Dry Eye - a Prospective Study

Study Overview
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Brief Summary
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The investigators aim to assess the effect of blepharoplasty with or without muller muscle resection on the symptoms of dry eye syndrome. this will be an observational study in which patients undergoing the aforementioned surgeries will be followed up and monitored for dry eye symptoms.

Detailed Description
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Patients who are referred for blepharoplasty with or without muller muscle resection in the oculoplastic clinic in the investigators institution, will be offered to participate in the study. After filling and informed consent form, patients recruited will fill in a questionnaire about dry eye symptoms, and will be examined by an ophthalmologist for visual acuity, intra ocular pressure, anterior segment examination using a slit lamp biomicroscopy, schirmer test, tear break up time assessment and tear osmolarity. These are all standard examination in ophthalmology. The surgical procedure planned to correct the eyelid pathology will not be affected by the results of these examinations. The same combination of ophthalmic examination will by done on postoperative follow-up examination 1 week, 1 month and 3 months after the surgery. Dry eye questionnaire will be filled in by the patients on postoperative follow-up examination 1 month and 3 months after the surgery. This data will help us assess the effect of these common surgical procedures on dry eye symptoms.

Official Title
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The Prevalence of Dry Eye Syndrome Among Patients Who Underwent Upper Eyelids Blepharoplasty With and Without Muller Muscle Resection

Conditions
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Ptosis, Dry Eye Syndrome, Dermatochalasis

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients who are referred for blepharoplasty with or without muller muscle resection in the oculoplastic clinic in our institution no other ophthalmic procedures planned for the patient in study period ability to undergo full ophthalmic examination as stated in the study protocol Ability to complete the dry eye questionnaire ability to sign an informed consent form Exclusion Criteria: previous eyelid surgery other orbital or lacrimal gland disease concurrent use of contact lenses concurrent use of Restasis previous glaucoma surgery use of punctual plugs pregnant or nursing women

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 120 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Blepharoplasty<br>patients undergoing upper eyelid blepharoplasty | |
| blepharoplasty and muller muscle resection<br>patients undergoing a combined blepharoplasty and muller muscle resection surgery | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Objective assessment of dry eye syndrome |  | 3 months postoperatively | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Subjective assessment of dry eye syndrome |  | 3 months postoperatively | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Muller muscle resection surgery, Dry eye syndrome, Blepharoplasty