Erector Spinae Plane Block in Renal Transplantation Donors

Study Overview
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Brief Summary
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Erector Spina Plan Block (ESPB) is a relatively new, easy-to-apply and safe regional anesthesia technique used to provide postoperative analgesia in various surgeries. Studies showing the clinical benefits of Erector Spina Plan block in renal transplantation surgery are limited to case reports. In this study, the effect of Erector Spina Plan Block on opioid consumption in postoperative period on donor patients who will undergo laparoscopic nephrectomy in renal transplantation surgery will be examined prospectively. The aim of the study is to provide analgesia to donor patients using less opioids by Erector Spina Plan Block and provide enhanced recovery.

Official Title
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Effects of Erector Spinae Plane Block on Opioid Consumption in Renal Transplantation Donors

Conditions
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Renal Transplantation, Laparoscopic Nephrectomy, Erector Spinae Plane Block

Intervention / Treatment
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* Procedure: Erector Spinae Plane Block
* Procedure: Intravenous fentanyl patient control device


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Donor patients scheduled for elective nephrectomy in renal transplantation surgery ASA I-II Patients who are aged between 18-75 Exclusion Criteria: Skin infection at the Erector Spina Plan Block area Coagulation disorder or using anticoagulant drugs End-stage organ and system failure Severe pulmonary and/or cardiovascular problems Substance addiction or known psychiatric or mental problems Chronic painkiller usage

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Erector Spinae Plane Block<br>Erector Spinae Plane Block will be administered to this group. | Procedure: Erector Spinae Plane Block<br>* Erector Spinae Plane Block will be administered before the surgery.<br>Procedure: Intravenous fentanyl patient control device<br>* 24-hour fentanyl consumption will be recorded.<br>|
| Active Comparator: Control Group<br>No regional anesthesia technique will be applied to the control group. | Procedure: Intravenous fentanyl patient control device<br>* 24-hour fentanyl consumption will be recorded.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Fentanyl consumption | The amount of fentanyl required by the patient and given by the device will be recorded for the first 24 hours. | Postoperative 24 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual Analog Scale | Pain of patients will be evaluated and recorded according to the Visual Analog Scale. | Postoperative 24 hours | 
| Modified Aldrete Score | Modified Aldrete Score will be used in patient recovery, and scores will be recorded at 5 minute intervals. | Postoperative 1 hour | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Laparoscopic Nephrectomy, Erector Spinae Plane Block