• Sleep Disturbance Among Patients With Psoriasis and Atopy and Comparison Between Them

Study Overview
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Brief Summary
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Comparison between sleep disturbance in atopy and psoriasis and control

Detailed Description
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Sleep is essential for daytime functioning and health and important for both psychological and physiological wellbeing . A growing body of research indicates that chronic sleep disturbance is associated with impaired quality of life (QoL) and a risk factor for poorer health, for example depression cardiovascular disease, hypertension 1 and diabetes. insomnia, the most common sleep disorder, is a clinical condition defined as difficulties falling asleep and/or maintaining sleep and/or poor sleep quality despite adequate opportunity for sleep resulting in significant daytime impairment. The development of insomnia in healthy populations has a bi-directional relationship with psychological factors such as anxiety, depressive symptoms and stress, and may in clinical populations also be associated with physical symptoms, such as pain. the physical symptoms in psoriasis, such as itch, one would expect a higher prevalence of sleep disturbance in this patient group. On the other hand Sleep disturbance is common also in patients with atopic dermatitis (AD). Patients with AD often have sleep disturbances due to pruritus.

Official Title
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• Sleep Disturbance Among Patients With Psoriasis and Atopy and Comparison Between Them

Conditions
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Sleep Disturbance

Intervention / Treatment
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* Behavioral: sleep disturbance


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: - patients with Psoriasis and Patients with A topic dermatitis Exclusion Criteria: All patient have another dermatological disease

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| psoriasis patients<br>sleep disturbance | Behavioral: sleep disturbance<br>* we observe sleep disturbance among patients with psoriasis and atopic dermatitis and control group<br>|
| atopic dermatites patients<br>sleep disturbance | Behavioral: sleep disturbance<br>* we observe sleep disturbance among patients with psoriasis and atopic dermatitis and control group<br>|
| control<br>sleep disturbance | Behavioral: sleep disturbance<br>* we observe sleep disturbance among patients with psoriasis and atopic dermatitis and control group<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| severity of the psooriasis (Psoriasis Area and Severity Index) | calculation of the severity through questionaire , 0 = None = Slight = Moderate = Severe = Very severe | 1 hour | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 2.HRQoL (Dermatology Life Quality Index); | The aim of this questionnaire is to measure how much your skin problem has affected your life OVER THE LAST WEEK The DLQI is calculated by summing the score of each question resulting in a maximum of 30 and a minimum of 0. The higher the score, the more quality of life is impaired. | 1 hour | 
| .insomnia severity [Insomnia Severity Index (ISI)]; | The Insomnia Severity Index has seven questions. The seven answers are added up to get a total score. When you have your total score Total score categories: 0-7 = No clinically significant insomnia 8-14 = Subthreshold insomnia 15-21 = Clinical insomnia (moderate severity) 22-28 = Clinical insomnia (severe) | 1 hour | 
| sleep quality [Pittsburgh Sleep Quality Index (PSQI)]; | The Pittsburgh Sleep Quality Index (PSQI) is an effective instrument used to measure the quality and patterns of sleep in adults. It differentiates poor from good sleep quality by measuring seven areas (components): subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbances, use of sleeping medications, and daytime dysfunction over the last month. A total score of 5 or greater is indicative of poor sleep quality. If you scored 5 or more it is suggested that you discuss your sleep habits with a healthcare provider | 1 hour | 
| stress (Perceived Stress Scale); | The Perceived Stress Scale (PSS) is the most widely used psychological instrument for measuring the perception of stress. It is a measure of the degree to which situations in one's life are appraised as stressful. 0 = Never 1 = Almost Never 2 = Sometimes 3 = Fairly Often 4 = Very Often | 1 hour | 
| itch (Itch Severity Scale); | The ISS consists of seven questions that measure the severity of itch and the extent to which QoL is affected. The total score ranges from zero to 21 | 1 hour | 
| and depressive symptoms (Beck Depression Inventory | This depression inventory can be self-scored 1-10____________________These ups and downs are considered normal 11-16___________________ Mild mood disturbance 17-20___________________Borderline clinical depression 21-30___________________Moderate depression 31-40___________________Severe depression over 40__________________Extreme depression | 1 hour | 
| severity of a topic dermatitis | The eczema area and severity index (EASI) Mild eczema score < 25 Moderate eczema score >25 <50 Severe eczema score >50 | 1 hour |