Development of a Developmental Prognostic Tool for the Premature Child Based on Automated Spontaneous Motor Analysis

Study Overview
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Brief Summary
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Prematurity is a major risk factor for poor neurodevelopmental outcomes. The clinical and neuroradiological evaluations proposed during the neonatal period to assess the developmental prognosis of children born prematurely are not sensitive and nor specific. The analysis of spontaneous motor activity by Prechtl's method has a better predictive value but is currently unfeasible in clinical routine. The study's principal objective is to describe the standardized values of complexity, variability, and fluidity of general movements.

Official Title
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Development of a Developmental Prognostic Tool for the Premature Child Based on Automated Spontaneous Motor Analysis

Conditions
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Premature Birth

Intervention / Treatment
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* Other: Acquisitions


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Birth before 33 week of amenorrhea; Hospitalization in the Neonatal Department of the Saint-Étienne University Hospital Patient affiliated or entitled to a social security scheme; Authorization to shoot the holders of parental authority; Consent to participate in the study by the holders of parental authority Exclusion Criteria: Need for ventilatory support; Difficulty of thermal regulation contraindicating the use of a heating cradle; Refusal of authorization to shoot by holders of parental authority; Refusal of participation in the study of holders of parental authority.

Ages Eligible for Study
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Minimum Age: 1 Day
Maximum Age: 3 Months

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| premature child<br>300 premature child will be included. They will have three acquisitions during hospitalization. | Other: Acquisitions<br>* Three acquisitions of 1 hours during hospitalization will be realized: a few days after hospitalization, in the middle of the hospitalization, a few days before hospital discharge. The child will be lying on his back in a heated cradle and filmed with a specific camera. The signal will be obtained by 2k ZED 2 stereo camera in order to obtain a three-dimensional location of the child<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Automatized quantification of complexity of general movements (spatial variation). | Measured by analyze of all acquisitions. | Year: 3 | 
| Automatized quantification of variability of general movements (temporal variations) | Measured by analyze of all acquisitions. | Year: 3 | 
| Automatized quantification of fluidity of general movements (uniform distribution) | Measured by analyze of all acquisitions. | Year: 3 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Comparison between our quantitative analysis and qualitative analysis according to the reference method of Pretchl | Measured by analyze of all acquisitions. | Year: 3 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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premature children, motor skill, developmental prognostic, prognostic tool