Body Perception and Complex Regional Pain Syndrome

Study Overview
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Brief Summary
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In CRPS, perturbation of body image and pseudo-neglect syndrome of the body part affected are frequently found. Pain and sensory perturbation seems to modify the way patients perceived their body part affected. Does a local body image perturbation can affect the balanced of the global self-awareness?

Detailed Description
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With the investigation of spontaneous sensations (SPS) according to the protocol of Michael and al (2011) the investigators study how patients can listen to their internal sensations located in other body part than the painful member in order to construct a representation of the body and maintain it in active consciousness. A group of controls will be included to understand if there is a global modification in the perception of SPS witch may be linked to the pathology.

Official Title
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Body Perception and Complex Regional Pain Syndrome : a Case-control Study

Conditions
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Complex Regional Pain Syndromes

Intervention / Treatment
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* Other: Sensory testing in the two hand
* Other: Neuropsychological evaluation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: For patients: • a diagnosis of CRPS of the lower limb according to the Budapest Criteria (men or women) For patients and control group Age ≥ 18 years Exclusion Criteria: For patients and control group neurological disease with cerebral repercussion or not stabilized serious physical illness; psychotropic medication disorders related to the use of a psychoactive substance (abuse, dependence or withdrawal); For patients: Presence of an other pain disorder

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patient<br>Patients suffering from CRPS of the lower limb Patients with sensory testing in the two hand and neuropsychological evaluation | Other: Sensory testing in the two hand<br>* spontaneous sensations while watching a hand<br>Other: Neuropsychological evaluation<br>* Score to anxiety-depression scale<br>|
| Control<br>Healthy controls match by age, gender, Body Mass Index Healthy volunteers with sensory testing in the two hand and neuropsychological evaluation | Other: Sensory testing in the two hand<br>* spontaneous sensations while watching a hand<br>Other: Neuropsychological evaluation<br>* Score to anxiety-depression scale<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Sensory testing | areas of the hand where spontaneous sensations were felt | day 1 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Neurological evaluation by questionary | Score to HAD (anxiety-depression) scale | day 1 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Complex Regional Pain Syndromes, Pain, Spontaneous sensations, interoception