Prescribe to Save Lives

Study Overview
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Brief Summary
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The U.S. is in the midst of an epidemic of opioid overdose deaths. The common use of opioids among persons living with HIV, along with their common use of benzodiazepines, has resulted in high rates of opioid overdose among this population. This study will test the implementation of evidence-based training, mentoring, technical support, and academic detailing to encourage HIV physicians to adopt evidence-based interventions to reduce overdose risk and treat opioid addiction.

Official Title
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Implementation to Motivate Physician Response to Opioid Dependence in HIV Settings

Conditions
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Opioid-Related Disorders, Drug Overdose

Intervention / Treatment
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* Behavioral: Implementation intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Clinicians and staff of HIV practice sites that: Receive Ryan White Funding; Treat adults with HIV; Have 3 or more prescribing clinicians; Have an electronic medical record (EMR) with an electronic medication list. Exclusion Criteria: Sites located in states with fewer than 500 Persons Living With HIV (PLWH) will be excluded
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Implementation intervention<br> | Behavioral: Implementation intervention<br>* The implementation intervention includes peer-to-peer training, post-training outreach, proactive expert support, and assistance with addressing environmental barriers.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in naloxone prescribing behavior | Number of clinicians that prescribe naloxone. This information will be collected from electronic medical record (EMR) data. | baseline to 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in perception about pharmacotherapy for opioid use disorder; 6-month | Opinions About Medication Assisted Treatment (OAMAT) survey | baseline to 6 months | 
| Change in perception about pharmacotherapy for opioid use disorder; 12-month | Opinions About Medication Assisted Treatment (OAMAT) survey | baseline to 12 months | 
| Change in prescribing motivation; 6 months | Change in Motivation Scale | baseline to 6 months | 
| Change in prescribing motivation; 12 months | Change in Motivation Scale | baseline to 12 months | 
| Change in prescriber training | Number of prescribers that have completed buprenorphine training. | baseline to 12 months | 
| Change in buprenorphine prescribing behavior | Prevalence of buprenorphine prescription. This information will be collected from EMR data. | baseline to 12 months |