Inter-rater and Intra-rater Reliability of the Global Eyebrow Assessment Scale

Study Overview
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Brief Summary
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This study evaluated the inter- and intra-rater reliability of the GEBA Scale with photonumeric guide for the assessment of overall eyebrow fullness. There is no treatment (intervention) associated with this study.

Conditions
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Healthy Volunteers

Intervention / Treatment
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* Drug: No Intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Willing to remove makeup and jewelry at each visit Willing to have photographs taken of the facial area Exclusion Criteria: Permanent eyebrow makeup (i.e., tattooing) or eyebrow implants of any kind Eyebrow extension application within 3 months of study entry Eyebrow tint or dye application within 2 months of study entry Eyebrow grooming (i.e., tweezing, waxing, or threading) between visits that is not part of the current routine

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| All Participants<br>Healthy volunteers. No treatment (intervention) was received. | Drug: No Intervention<br>* No Intervention.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Inter-rater Reliability of Physician Raters Using the Global Eyebrow Assessment (GEBA) Scale | Inter-rater agreement (among raters) of the GEBA scores (1=very sparse, 2=sparse, 3=full, 4=very full) to assess eyebrow fullness was evaluated using Kendall's coefficient of concordance (Kendall's W). Each of 7 raters scored 112 subjects' eyebrows using the GEBA Scale at 2 different time points at day 1. The overall inter-rater agreement for Kendall's W for all raters combined was estimated based on the average of the scores from those 2 different time points. The degree of agreement of the point estimates of Kendall's W was interpreted according to the reference range scale that was pre-defined as: ≤ 0: poor, 0.00-0.20: slightly, 0.21-0.40: fair, 0.41-0.60: moderate, 0.61-0.80: substantial and 0.81-1:00: almost perfect. The 95% confidence interval for Kendall's W was provided. | Day 1 | 
| Intra-rater Reliability of Physician Raters Using the Global Eyebrow Assessment (GEBA) Scale | Intra-rater (within raters) agreement of the GEBA scores (1=very sparse, 2=sparse, 3=full, 4=very full) to assess eyebrow fullness was evaluated by weighted Kappa statistics. Weighted Kappa statistics were calculated for each of 7 raters who evaluated 112 subjects using GEBA scale, assessing agreement between 2 different time points at day 1. The overall intra-rater agreement for Kappa statistics for all raters combined was estimated by pooling Kappa statistics for each rater using a chi-square statistic. The degree of agreement of the point estimates of Kappa statistics was interpreted according to the reference range scale that was predefined as: ≤ 0: poor, 0.00-0.20: slightly, 0.21-0.40: fair, 0.41-0.60: moderate, 0.61-0.80: substantial and 0.81-1:00: almost perfect. The 95% confidence interval for Kappa statistics was provided. | Day 1 |