Family Intervention for Mental Illness and Substance Abuse

Study Overview
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Brief Summary
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This study will evaluate a family intervention program for individuals with bipolar disorder, schizophrenia, or schizoaffective disorder and co-occurring substance use disorders.

Detailed Description
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Substance use disorder (SUD) in persons with severe mental illness may worsen the course of psychiatric illness. The loss of family support for individuals with mental illness is a major contributing factor to housing instability, homelessness, and other problems. Despite progress toward integrating mental health and substance abuse services, interventions that improve the course of mental illness while helping the families of the mentally ill are not currently available. Enhancing skills for coping with mental illness may be an effective strategy for treating SUD, decreasing caregiver burden, and improving the long-term outcomes for people with mental illness. Patients and their families are randomly assigned to either the Family Intervention for Dual Diagnosis (FIDD) program or family psychoeducation. The FIDD program lasts for up to 3 years and includes both single and multiple-family group formats. The family psychoeducation program consists of 6 weekly sessions. Routine assessments are conducted on all patients, and relatives are evaluated on a wide range of outcomes, including substance abuse, hospitalizations, psychiatric symptoms, legal problems, aggression, housing and homelessness, family burden, social support, and quality of life. To determine the effectiveness of the FIDD program, knowledge of mental illness and problem-solving skills are assessed in the families following treatment.

Official Title
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Family Intervention for SMI and Substance Use Disorder

Conditions
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Schizophrenia, Bipolar Disorder, Substance-related Disorders

Intervention / Treatment
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* Behavioral: Family Intervention for Dual Diagnosis
* Behavioral: Family psychoeducation program


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Have schizophrenia, schizoaffective disorder, or bipolar disorder Have a current substance use disorder (within the past 6 months) Are willing to have at least 4 hours of contact per week with family members or significant others Plan to remain in the community Have family members or significant others who consent to participate in the study and plan to remain in the community

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 1<br>Participants will undergo the Family Intervention for Dual Diagnosis (FIDD) program. | Behavioral: Family Intervention for Dual Diagnosis<br>* The family intervention for dual diagnosis program lasts for up to 3 years and includes both single and multiple-family group formats.<br>|
| Active Comparator: 2<br>Participants will be placed in a family psychoeducation program. | Behavioral: Family psychoeducation program<br>* The family psychoeducation program consists of 6 weekly sessions.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Alcohol use scale-revised |  | Measured at baseline, during treatment, and post-treatment | 
| Drug use scale-revised |  | Measured at baseline, during treatment, and post-treatment | 
| Substance abuse treatment scale |  | Measured at baseline, during treatment, and post-treatment | 
| Timeline followback calandar |  | Measured at baseline, during treatment, and post-treatment | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Psychotic Disorders, Schizoaffective Disorder, Substance Abuse