Combination of Dental Bleaching Techniques, Randomized Clinical Trial

Study Overview
=================
Brief Summary
-----------------
To determine the effectiveness of combining different concentrations of hydrogen peroxide and carbamide used during tooth bleaching.

Detailed Description
-----------------
120 patiens over 18 years old. Design: Hydrogen peroxide (HP) Carbamide Peroxide (CP) Group 1: CP 10% + HP 40% Group 2: CP 15% + HP 40% Group 3: CP 20% + HP 40% Group 4: HP 10% + HP 40%

Official Title
-----------------
Combination of Dental Bleaching Techniques, Randomized Clinical Trial

Conditions
-----------------
Tooth Stain

Intervention / Treatment
-----------------
* Other: Hydrogen Peroxide and Carbamide Peroxide
* Other: Hydrogen Peroxide and Hydrogen Peroxide


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: 18 - 45 years old Student, teacher or administrative personnel at UNIBE. Exclusion Criteria: Dental Hypersensitivity Periodontal disease Active caries lesions Allergy to latex Orthodontic treatment

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: CP 10% + HP 40%<br>Carbamide Peroxide 10% + Hydrogen Peroxide 40% were administered to each patient on this group. CP at home and HP at office | Other: Hydrogen Peroxide and Carbamide Peroxide<br>* Carbamide Peroxide + Hydrogen Peroxide were administered to each patient on this group. HP 10% at home and HP 40% at office<br>|
| Active Comparator: CP 15% + HP 40%<br>Carbamide Peroxide 15% + Hydrogen Peroxide 40% were administered to each patient on this group.CP at home and HP at office | Other: Hydrogen Peroxide and Carbamide Peroxide<br>* Carbamide Peroxide + Hydrogen Peroxide were administered to each patient on this group. HP 10% at home and HP 40% at office<br>|
| Active Comparator: CP 20% + HP 40%<br>Carbamide Peroxide 20% + Hydrogen Peroxide 40% were administered to each patient on this group.CP at home and HP at office | Other: Hydrogen Peroxide and Carbamide Peroxide<br>* Carbamide Peroxide + Hydrogen Peroxide were administered to each patient on this group. HP 10% at home and HP 40% at office<br>|
| Active Comparator: HP 10% + HP 40%<br>Hydrogen Peroxide 10% + Hydrogen Peroxide 40% were administered to each patient on this group. HP at Home and HP at office | Other: Hydrogen Peroxide and Hydrogen Peroxide<br>* Hydrogen Peroxide + Hydrogen Peroxide were administered to each patient on this group. HP at home and HP at office<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in color after the intervention | The color was taken with conventional hade guide VITA by human observation, with the color range from A to D, each color range with 5 classifications. (Ej. A1, A2, A3, A4, A5) | Two weeks | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Peroxide