Chronic Heart Failure Analysis and Registry in the Tohoku District 2 (CHART-2 Study)

Study Overview
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Brief Summary
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Chronic Heart Failure Analysis and Registry in the Tohoku District 2 (CHART-2 Study) is a large, prospective, hospital-based cohort study to investigate the following: Characteristics of patients with chronic heart failure and prognostic risks of these patients. Characteristics of patients with high risk for heart failure and critical factors which predict the development of symptomatic heart failure in these patients. The incidence and prognostic impact of metabolic syndrome in patients with chronic heart failure. The association between metabolic syndrome and the development of symptomatic heart failure.

Detailed Description
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The CHART-2 Study is a multicenter prospective observational cohort study identifying the characteristics, mortality and prognostic risks of patients with overt HF and patients without HF but who are at high risk for disease progression of cardiovascular diseases (CVD). The purposes of the study are as follows: to elucidate characteristics of patients with overt HF and the associated prognostic risks to elucidate characteristics of patients at risk for HF and the factors associated with CVD progression to elucidate factors associated with the development of AHFS to elucidate prevalence and prognostic impact of metabolic syndrome (MetS) in patients with overt HF to elucidate the association between MetS and the development of AHFS to elucidate the prevalence and prognostic impact of malignancy in patients with CVD to elucidate the prevalence of patients needing home nursing care and the characteristics of bedridden patients with CVD.

Official Title
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Chronic Heart Failure Analysis and Registry in the Tohoku District 2 (CHART-2 Study)

Conditions
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Heart Failure, Coronary Disease, Heart Valve Diseases, Cardiomyopathies, Left Ventricular Hypertrophy

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Structural heart disease but without signs or symptoms of heart failure. Structural heart disease with prior or current symptoms of heart failure. Refractory heart failure requiring specialized interventions. Patients with prior cardiovascular surgery or percutaneous coronary intervention and those who need such interventions. Exclusion Criteria: Patients with age<20 years old. Patients who refused to participate.

Ages Eligible for Study
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Minimum Age: 20 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| All-cause death |  | At the time of registration and at least once a year thereafter | 
| Non-fatal acute myocardial infarction |  | At the time of registration and at least once a year thereafter | 
| Non-fatal stroke |  | At the time of registration and at least once a year thereafter | 
| Heart failure requiring admission |  | At the time of registration and at least once a year thereafter |