Kinematic Analysis in Stroke Patients Using Microsoft Kinect and Akira Software: Kinect-Akira Movement Study

Study Overview
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Brief Summary
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In this prospective, unicentric, case-control study, the main aim is to analyze joint movement and walking patterns in patients with acute stroke with a marker-free motion capture system. Case group: Stroke patients who fulfill the inclusion criteria are invited to participate in the study during admission. The evaluation consists of a workout designed by expert rehabilitation physicians and neurologists that is performed by the patient in front of the Microsoft Kinect camera. The custom-built software Akira record the joint angles of body trunk and upper limbs during the workout. The kinematic data will be analyzed with a machine learning algorithm that classifies the participant according to the kinematic data in normal movement or impaired movement (with the degree of impairment) by age decade. Control group: healthy participants (without neurological or osteomuscular diseases) matched by age and sex with cases 1:1. The correlation between kinematic and clinical scales (NIHSS) and functional scales (modified Rankin Scale) will be analyzed. A secondary objective will be to analyze the predictive value of the kinematic measurements with the functional outcome at three months

Official Title
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Kinematic Analysis in Stroke Patients Using Microsoft Kinect and Akira Software: Kinect-Akira Movement Study

Conditions
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Stroke

Intervention / Treatment
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* Other: Kinematic metrics


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Acute Stroke patients (within the first week of index stroke) Neurological deficit present at the moment of the evaluation. Informed consent signed. Exclusion Criteria: Clinical instability Aphasia or cognitive decline that prevents the understanding of the workout. Refuse to participate Previous neurological or osteomuscular conditions. Previous conditions with less than 3 months of expectancy of life.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Cases<br>Acute stroke patients during the first week of evolution | Other: Kinematic metrics<br>* kinematic metrics recorded with Kinect (register brand) and extracted with Akira (register brand)<br>|
| Control<br>Age and sex 1:1 healthy participants | Other: Kinematic metrics<br>* kinematic metrics recorded with Kinect (register brand) and extracted with Akira (register brand)<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Kinematic metrics: join angles | The kinect camera together with the software Akira will be used to automatically measure the degree angle of the following body joints: shoulder in abduction, shoulder inflexion, elbow in extension and in flexion and the angle formed by the forearm and the trunk with the shoulder in abduction. | The change between the first week of index stroke (acute phase) and at 3 months after index stroke | 
| Kinematic metrics: movement acceleration | The kinect camera together with the software Akira will be used to automatically measure the acceleration of the following movements: shoulder abduction and shoulder flexion. | The change between the first week of index stroke (acute phase) and at 3 months after index stroke | 
| Kinematic metrics: movement pattern | The kinect camera together with the software Akira will be used to automatically measure the pattern of the following movements: trunk oscillation during standing position and during walking; and trunk oscillation during seating position with opened and closed eyes. | The change between the first week of index stroke (acute phase) and at 3 months after index stroke | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Relationship of kinematic measures with the degree of disability after stroke. | Correlation between the kinematic metrics described before (joint angles, movement acceleration and movement pattern) and the degree of disability, measured y the modified Rankin scale. The modified Rankin Scale (mRS) is a extensively use scale to measure dependency after stroke. The minimum value is 0 (no sequels or disability) and the maximum value is 6 (dead). The lower the score in the scale, the better is the outcome. | At 3 months after the index stroke |