Sedation Level on Machine Learning With Electroencephalogram in Painless Gastroenteroscopy Patients

Study Overview
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Brief Summary
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Painless endoscopy technology can make patients comfortable under anesthesia, but because of the painless inside.The diagnosis and treatment time of endoscopic examination is short, and the transport is fast. Anesthesia related wind such as deep breathing depression and hypoxemia will occurRisks.Eeg depth monitoring can assist anesthesiologists to evaluate the depth of anesthesia and reduce the risk. Artificial intelligence is adopted.There are few reports on the evaluation of anesthesia depth and drug dosage by electroencephalogram (EEG) monitoring in outpatient patients with painless gastroenteroscopy.

Detailed Description
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1.examination, and establish brainClassification model of electrogram and sedation depth;2. The EEG characteristics, basic information and propofol were administered to all patients.The dose model of propofol painless gastroenteroscopy was established by machine learning to guide anesthesia Drug use;3. Evaluate the time and space complexity of the model, build the model, and assist the anesthesiologist to individualize the patient Chemical, safe and comfortable management.

Official Title
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Sedation Level Estimation Based on Machine Learning of Quantitative Occipital Electroencephalogram Features in Gastroenteroscopy Patients

Conditions
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Gastritis

Intervention / Treatment
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* Drug: Propofol
* Device: EEG montior


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Painless gastroenteroscopy patients ASA classification is Ⅰ-Ⅱ Patients who are willing to cooperate No schizophrenia,epilepsy and other neurological diseases Exclusion Criteria: allergic to propofol Patients who are unwilling to cooperate Patients with psychiatric disorders Patients using sedative drugs for a long time Patients with neuropsychiatric disorders Patients with severe heart, liver, kidney and respiratory diseases

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| The propofol group<br>Patients undergoing painless gastroenteroscopy under general anesthesia | Drug: Propofol<br>* And pump propofol at a rate of 600ml/h. The degree of sedation was assessed by the MOAA/S scale until the depth sadation of the patient during the monitor of EEG<br>Device: EEG montior<br>* And pump propofol at a rate of 600ml/h. The degree of sedation was assessed by the MOAA/S scale until the depth sadation of the patient during the monitor of EEG<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Electroencephalogram features | Time feature;frequency feature;Entropy | during gastroenteroscopy procedure | 
| Propofol dosage | from awake to sedation in painless gastroenteroscopy | during gastroenteroscopy procedure | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| physiological parameter(blood pressure ) | from awake to sedation in painless gastroenteroscopy with ECG monitor | during gastroenteroscopy procedure | 
| physiological parameter(heart rate ) | from awake to sedation in painless gastroenteroscopy with ECG monitor | during gastroenteroscopy procedure | 
| physiological parameter(oxygen saturation ) | from awake to sedation in painless gastroenteroscopy with ECG monitor | during gastroenteroscopy procedure | 
| time parameter （Arousal times） | with monitor and Anesthesiologist's record | during endoscopy | 
| success rate of once endoscopy | with monitor and Anesthesiologist's record | during endoscopy | 
| Incidence of hypoxemia | with monitor and Anesthesiologist's record | during endoscopy | 
| Endoscopist satisfaction by questionnaire | with monitor and Anesthesiologist's record | during endoscopy | 
| vasoactive drugs | with monitor and Anesthesiologist's record | during endoscopy | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Deep Sedation, Machine learning, EEG characheristics;, Painless gastroscopy