Comparison of Tidal Volume Between Pediatric Anaesthesia and Paediatric Intensive Care Patients

Study Overview
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Brief Summary
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Paediatric anaesthesiology and paediatric intensive care unit data will be retrospectively screened for the data regarding mechanical ventilation. The primary aim will be the tidal volume setting and the secondary the level of positive end-expiration pressure (PEEP) according to the inspired oxygen fraction (FIO2), and the level of driving pressure.

Detailed Description
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Protective positive pressure ventilation (tidal volume ≤6 mL/kg) in adult patients in intensive care is currently considered as a standard procedure. It is associated with a reduction of morbidity and positive outcome. In paediatric patients there are available only limited information related to the size of the tidal volume and it is recommended to use the volume between 5 and 8 mL per kg for the whole spectrum of ages of pediatric patients. The aim of this retrospective observational study is to evaluate the tidal volumes used in clinical practice in pediatric patients during general anesthesia and compared it to the tidal volumes used in paediatric critical care. Data will be harvested from the anaesthesiology records and from the paediatric intensive care unit charts. The tidal volume will calculated per kg of actual weight.

Official Title
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Comparison of Tidal Volume Between Pediatric Anaesthesia and Paediatric Intensive Care Patients: Retrospective Study

Conditions
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Protective Ventilation

Intervention / Treatment
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* Other: Data from anaesthesia records for ventilation setting screening
* Other: Data from intensive care records for ventilation setting screening


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Paediatric patients on mechanical ventilation in anaesthesia department Paediatric patients on mechanical ventilation in intensive care department In selected study period between 1.1.2018 - 31.1.2019 Exclusion Criteria: Age outside selected limits Insufficient data

Ages Eligible for Study
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Maximum Age: 19 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Paediatric patients anaesthesia<br>Paediatric patients who underwent diagnostic or surgical procedure under general anaesthesia with the need for mechanical ventilation in the selected time period. | Other: Data from anaesthesia records for ventilation setting screening<br>* Data from anaesthesia records will be retrospectively screened for the ventilation settings<br>* Other names: Retrospective data analysis;|
| Paediatric patients intensive care<br>Paediatric patients admitted to the paediatric intensive care unit with the need for mechanical ventilation in the selected time period | Other: Data from intensive care records for ventilation setting screening<br>* Data from paediatric intensive care charts will be retrospectively screened for the ventilation settings<br>* Other names: Retrospective data analysis;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Tidal volume | Tidal volume will be evaluated in the paediatric patients in anaesthesia and in intensive care unit | Intraoperative period | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Positive end-expiratory pressure settings according to the inspiration fraction of oxygen | Positive end-expiratory pressure will be evaluated in the paediatric patients in anaesthesia and in intensive care unit | Intraoperative period | 
| Driving pressure | Driving pressure will be calculated from peak pressure minus PEEP in patients on mechanical ventilation in anaesthesia and in intensive care unit | Intraoperative period | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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ventilation, paediatric patient, mechanical ventilation