Medial Cervical Block for Carotid Endarterectomy Comparison With Standard Method

Study Overview
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Brief Summary
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The purpose of the study is to compare efficacy, complications and safety of the standard method of Combined (superficial and deep) cervical plexus block (SDCPB) with Ultrasound guided Medial Cervical plexus block technique (MCPB). Hypothesis: Ultrasound assisted MCPB is safer than SDCPB with similar efficacy.

Official Title
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A Comparison of Medial Cervical Plexus Block Versus Combined (Superficial and Deep) Cervical Plexus Block for Carotid Endarterectomy: A Prospective, Randomized Single Blind Study

Conditions
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Cervical Plexus Block Comparison

Intervention / Treatment
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* Procedure: cervical block


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients undergoing Elective Carotid Endarterectomy Exclusion Criteria: Denied consent to block performance, Emergency procedure

Ages Eligible for Study
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Minimum Age: 30 Years
Maximum Age: 90 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Combined Cervical Block<br> | Procedure: cervical block<br>* In brief, the superficial block was performed using a 22G needle (07 x 40 mm). The mixture injected was 15 ml of 0.5% bupivacaine + 10 ml of 1% lidocaine. Deep cervical plexus block was performed using a Stimuplex DR stimulating needle and the dose of anaesthetic used was 10 ml 0.5% bupivacaine + 5 ml 1% lidocaine applied in the vicinity of the C3 nerve root. The MCPB performed using ultrasound-guidance aiming specifically for the interfascia space. Eighteen ml of 0.375% bupivacaine was injected into the interfascia space at the level of C3 vertebral body using a 22G needle (07 x 40 mm).<br>|
| Active Comparator: Median Cervical Block US guided<br> | Procedure: cervical block<br>* In brief, the superficial block was performed using a 22G needle (07 x 40 mm). The mixture injected was 15 ml of 0.5% bupivacaine + 10 ml of 1% lidocaine. Deep cervical plexus block was performed using a Stimuplex DR stimulating needle and the dose of anaesthetic used was 10 ml 0.5% bupivacaine + 5 ml 1% lidocaine applied in the vicinity of the C3 nerve root. The MCPB performed using ultrasound-guidance aiming specifically for the interfascia space. Eighteen ml of 0.375% bupivacaine was injected into the interfascia space at the level of C3 vertebral body using a 22G needle (07 x 40 mm).<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| number of additional applications of short-acting local anaesthetic | The number of times a surgeon would have to supplement the Regional Block with intrafield application of increments of short-acting local anaesthetic | intraoperatively | 
| patient satisfaction |  | 24 h after operation | 
| Complications |  | perioperative | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Ultrasound, Cervical Plexus, Anesthesia, Conduction, Surgical Procedures, Elective, Atherectomy