Response of Metabolic Syndrome and Sexual Dysfunction to Lifestyle Changes in Men With Psoriasis

Study Overview
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Brief Summary
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complaint of sexual dysfunction and metabolic syndrome are highly reported in men with psoriasis

Detailed Description
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erectile dysfunction (ED) psoriatic men with metabolic syndrome (number of the patients will be 60) will assigned to study group (group = 30 patients) that will receive lifestyle changes (12 weeks of low calorie diet and moderate-intensity walking on treadmill, the walking duration will be 40 minutes, the walking will be three times per week) or control group (group=30 patients) that will receive no lifestyle changes/modifications.

Official Title
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Response of Metabolic Syndrome and Sexual Dysfunction to Lifestyle Changes/Modifications in Men With Psoriasis

Conditions
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Psoriasis, Metabolic Syndrome, Erectile Dysfunction

Intervention / Treatment
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* Behavioral: lifestyle modification (exercise and control of diet)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: psoriatic married men with metabolic syndrome and erectile dysfunction Exclusion Criteria: patients with heart, respiratory, other autoimmune problems

Ages Eligible for Study
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Minimum Age: 35 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: lifestyle-modification group<br>erectile dysfunction (ED) psoriatic men with metabolic syndrome (group = 30 patients) will receive lifestyle changes (12 weeks of low calorie diet and moderate-intensity walking on treadmill, the walking duration will be 40 minutes, the walking will be three times per week) | Behavioral: lifestyle modification (exercise and control of diet)<br>* erectile dysfunction (ED) psoriatic men with metabolic syndrome that will receive lifestyle changes (12 weeks of low calorie diet and moderate-intensity walking on treadmill, the walking duration will be 40 minutes, the walking will be three times per week)<br>|
| No Intervention: control group<br>erectile dysfunction (ED) psoriatic men with metabolic syndrome (number of the patients will be 30) that will receive no lifestyle changes/modifications. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| International Index of Erectile Function | Arabic version of this 5-item questionnaire will used to assess erectile function/dysfunction | It will be measured after 12-week intervention | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| psoriasis area and severity index | it is a tool used to measure the severity and extent of psoriasis. | It will be measured after 12-week intervention | 
| body mass index | patients will be assessed with empty bowel and bladder | It will be measured after 12-week intervention | 
| systolic blood pressure | it will be measured using sphygmomanometer | It will be measured after 12-week intervention | 
| diastolic blood presure | it will be measured using sphygmomanometer | It will be measured after 12-week intervention | 
| waist circumference | it will be measured by in elastic tape | It will be measured after 12-week intervention | 
| blood glucose | it will be measured in fasting status | It will be measured after 12-week intervention | 
| triglycerides | it will be measured in serum | It will be measured after 12-week intervention | 
| high density lipoprotein | it will be measured in serum | It will be measured after 12-week intervention |