Gait Analysis of Ankle Arthroplasty and Arthrodesis

Study Overview
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Brief Summary
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Surgical options for managing hindfoot arthritis include: joint fusion, total ankle joint replacement or osteotomies (realignment) of bones. Fusion of arthritic hindfoot joints has been the accepted method of managing hindfoot arthritis for over a century. Recently, total ankle replacement has evolved as a treatment option for patients with end stage ankle arthritis. A comparison of gait for patients before and after hindfoot fusion or total ankle replacement will give further information about the outcome of this treatment. The principal aim of this project is to assess the effect of total ankle replacement or hindfoot fusion on gait. We are also interested in the outcome of the surgery and its effect on your symptoms (eg. pain and mobility). The results of this study will aid researchers in assessing this new treatment modality. Your involvement in this study is critical for the researchers to further analyze this new form of treatment and your time and involvement is appreciated.

Official Title
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Gait Analysis of Patients Undergoing Total Ankle Arthroplasty, Ankle Arthrodesis, Tibiotalocalcaneal or Pantalar Fusion.

Conditions
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Ankle Arthritis

Intervention / Treatment
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* Behavioral: Gait Analysis


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Symptomatic Ankle Arthritis Skeletal maturity Able to give informed consent Exclusion Criteria: Avascular Necrosis of Talus Obesity (BMI >30) Prior Ankle fusion or arthroplasty Active or prior infection within 12 months Medical condition precluding major surgery Severe ipsilateral mid or hind foot deformity Severe osteoporotic or osteopenic bone Neuromuscular impairment Age less than 40 years old Cognitive or psychiatric impairment prohibiting accurate follow-up Pregnancy Workers compensation board patients

Ages Eligible for Study
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Minimum Age: 40 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Ankle Arthoplasty<br>Patients will undergo a Total Ankle Replacement procedure | Behavioral: Gait Analysis<br>* A computerized motion analysis system to observe the effect of ankle arthroplasty versus ankle arthrodesis on the kinematic behaviour of the foot and ankle during gait.<br>|
| Active Comparator: Ankle fusion<br>Patients will undergo an Ankle Arthrodesis procedure | Behavioral: Gait Analysis<br>* A computerized motion analysis system to observe the effect of ankle arthroplasty versus ankle arthrodesis on the kinematic behaviour of the foot and ankle during gait.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The primary outcome measure will be micro motion, consisting of component migration and rotation relative to the talus and distal tibia. This will be measured utilizing RSA with bi-planar stereo X-rays taken at several intervals: before weight bearing is |  | 12 months |