Compare Outcomes of CPR Between the Video-laryngoscopy (VL) Users and the Direct-laryngoscopy (DL) Users

Study Overview
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Brief Summary
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This is a clinical study based on the analysis of video-clip data of cardiopulmonary resuscitation (CPR) and clinical data for out of hospital cardiac arrest patients between 2011 and 2015. Aim of study is to compare the endotracheal intubation performance and CPR outcomes between videolaryngoscopy (VL) and direct laryngoscopy (DL) users.

Detailed Description
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Endotracheal intubation (ETI) has been considered to be the best method of airway management during cardiopulmonary resuscitation (CPR). However ETI during CPR is a highly skill-dependent procedure, then it should be attempted only highly trained physicians. Because of technical difficulty in using direct laryngoscopy (DL), various types of videolaryngoscopy (VL) devices using micro-camera technology have been designed to overcome the problems of DL. This study tried to compare the recovery of spontaneous circulation (ROSC) and survival discharge between use of standard device (DL) and VL in a real clinical setting. In addition, this study also compare the first pass success rate of ETI,speed of ETI, incidences of complications, and chest compression interruptions during cardiopulmonary resuscitation between both device users.

Official Title
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Improvement of Recovery of Spontaneous Circulation and Survival Using the Video-laryngoscopy for out-of Hospital Cardiac Arrest Patient

Conditions
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Cardiopulmonary Arrest

Intervention / Treatment
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* Procedure: Endotracheal Intubation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients who suffer sudden out-of hospital cardiac arrest Exclusion Criteria: Cardiac arrests from multiple trauma Cases of requesting the do-not attempt resuscitation before ETI Intubated cases before arrival to emergency department

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: DL user<br>Experienced emergency physicians who primarily used the direct laryngoscopy (DL) for endotracheal intubation during cardiopulmonary resuscitation. | Procedure: Endotracheal Intubation<br>* Insertion of endotracheal tube into the trachea and supply oxygen using the Ambu-bagging during cardiopulmonary resuscitation<br>|
| Active Comparator: VL user<br>Experienced emergency physicians who primarily used the videolaryngoscopy (VL) for endotracheal intubation during cardiopulmonary resuscitation. | Procedure: Endotracheal Intubation<br>* Insertion of endotracheal tube into the trachea and supply oxygen using the Ambu-bagging during cardiopulmonary resuscitation<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Survival with good neurologic outcome | Survived patients who were conscious and able to perform independent activities of daily life (CPC1 or CPC2) | 6 months after emergency department visit | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| ROSC | Recovery of spontaneous circulation by successful resuscitation | within 1 hour after emergency department visit | 
| total time to complete ETI from the beginning | time from the advancement of the blade into the patient's mouth to the delivery of the first successful ventilation using the bag | within 1 hour after emergency department visit | 
| complication | Presence of chest compression interruption, esophageal intubation and dental injuries | within 1 hour after emergency department visit | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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intubation, Cardiopulmonary Resuscitation