Alveolar Ridge Preservation Techniques After Tooth Extraction

Study Overview
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Brief Summary
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The aim of the present randomized controlled trial (RCT) was to evaluate the efficacy of different alveolar ridge preservation (ARP) techniques on hard tissue dimensional alterations after tooth extraction, based on clinical measurements.

Detailed Description
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Thrirty-six patients were randomly assigned in four treatment groups: A) freeze-dried bone allograft (FDBA) covered with collagen sponge (CS), B) FDBA covered with free gingival graft (FGG), C) demineralized bovine bone mineral xenograft (DBBM) covered with FGG and D) FGG without socket grafting. Clinical measurements were performed immediately after tooth extraction and 4 months later. The related outcomes pertained to both vertical and horizontal assessment of bone loss

Official Title
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Clinical Evaluation of Different Alveolar Ridge Preservation Techniques After Tooth Extraction: a Single- Center, Triple Blinded Randomized Clinical Trial.

Conditions
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Alveolar Bone Loss

Intervention / Treatment
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* Other: Alveolar ridge preservation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: systematically healthy patients non-smokers no use of antibiotics for the last 3 months presence of a non-restorable single-rooted tooth in the maxilla. Exclusion Criteria: Patients were excluded when a bony wall loss of more than 50% was verified for the socket after the extraction

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Alveolar ridge preservation with particulated allograft covered with collagen sponge.<br>Alveolar ridge preservation after tooth extraction. Freeze-dried bone allograft (FDBA) was applied in the socket immediatelly after tooth extraction and it was covered with collagen sponge (CS). | Other: Alveolar ridge preservation<br>* application of different bone graft and sealing means after tooth extraction<br>|
| Experimental: Alveolar ridge preservation with particulated allograft covered with autogenous soft tissue punch<br>Alveolar ridge preservation after tooth extraction. Freeze-dried bone allograft (FDBA) was applied in the socket immediatelly after tooth extraction and it was covered with free gingival graft (FGG). | Other: Alveolar ridge preservation<br>* application of different bone graft and sealing means after tooth extraction<br>|
| Experimental: Alveolar ridge preservation with particulated xenograft covered with autogenous soft tissue punch<br>Alveolar ridge preservation after tooth extraction. Demineralized bovine bone mineral xenograft (DBBM) was applied in the socket immediatelly after tooth extraction and it was covered with free gingival graft (FGG). | Other: Alveolar ridge preservation<br>* application of different bone graft and sealing means after tooth extraction<br>|
| Experimental: Alveolar ridge preservation without bone grafting covered with socket sealing mean<br>Alveolar ridge preservation after tooth extraction. No bone graft was applied and the socket was covered with free gingival graft (FGG). | Other: Alveolar ridge preservation<br>* application of different bone graft and sealing means after tooth extraction<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Vertical dimensional alterations of the alveolar ridge, after tooth extraction. | Assessment of the alteration of the alveolar ridge height after different alveolar ridge preservation techniques, based on clinical measurements. Clinical measurements were carried out immediately after tooth extraction and 4 months later. Distances in those clinical measurements were recorded in 0.1 mm increments, using a digital calliper (Logilink digital caliper WZ0031). | 4 months | 
| Horizontal dimensional alterations of the alveolar ridge, after tooth extraction. | Assessment of the alteration of the alveolar ridge width after different alveolar ridge preservation techniques, based on clinical measurements. Clinical measurements were carried out immediately after tooth extraction and 4 months later. Distances in those clinical measurements were recorded in 0.1 mm increments, using a digital calliper (Logilink digital caliper WZ0031). | 4 months |