BEAM COPD: Breathing, Education, Awareness and Movement in Chronic Obstructive Pulmonary Disease (COPD)

Study Overview
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Brief Summary
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The main purpose of this study is to determine feasibility and effects of tai chi and mind-body breathing in patients with COPD.

Official Title
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BEAM COPD: Breathing, Education, Awareness and Movement in Chronic Obstructive Pulmonary Disease

Conditions
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Chronic Obstructive Pulmonary Disease (COPD)

Intervention / Treatment
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* Behavioral: Tai chi
* Behavioral: Mind-body breathing
* Behavioral: Education


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Moderate-severe COPD Age ≥ 40 years Exclusion Criteria: Subjects with respiratory failure or GOLD stage 4 who are unable to safely perform a 6 minute walk test or otherwise safely exercise as deemed by a physician. COPD exacerbation requiring steroids, antibiotics, ED visit or hospitalization within the past 2 weeks unless physician deems subject at baseline Planned major pulmonary intervention within the next 3 months Hypoxemia on walk test or cardiopulmonary exercise test Inability to ambulate due to vascular or other neuromuscular conditions that would preclude a walk test Clinical signs of unstable cardiovascular disease Severe cognitive dysfunction Non-English speaking Current active participation in pulmonary rehabilitation program or current regular practice of tai chi Physician diagnosis of unstable/untreated clinical depression History of lung cancer

Ages Eligible for Study
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Minimum Age: 40 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: tai chi exercise<br> | Behavioral: Tai chi<br>* 12 week tai chi class<br>|
| Experimental: mind-body breathing<br> | Behavioral: Mind-body breathing<br>* 12 week breathing class<br>|
| Active Comparator: education<br> | Behavioral: Education<br>* 12 week education class<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Feasibility of tai chi intervention | Willingness to participate, adherence, and safety | 12 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change from baseline- Disease specific quality of life | Chronic Respiratory Questionnaire | baseline, 12 weeks, 24 weeks | 
| Change from baseline- Exercise capacity | six-minute walk distance, cardiopulmonary exercise testing | baseline, 12 weeks, 24 weeks | 
| Change from baseline- Dyspnea | UCSD Shortness of Breath Questionnaire | baseline, 12 weeks, 24 weeks | 
| Change from baseline- Psychosocial well-being | CES-D, Perceive Stress Scale, COPD Self-Efficacy Scale, Multidimensional Scale of Percieved Social Support | baseline, 12 weeks, 24 weeks | 
| Change from baseline- Pulmonary function | Spirometry and lung volumes | baseline, 12 weeks, 24 weeks | 
| Change from baseline- Physical strength and flexibility | Chair Sit and Reach, Chair Stand | baseline, 12 weeks, 24 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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chronic bronchitis, emphysema, pulmonary, COPD