Study of Complication Rates Associated With PICC for Left vs Right

Study Overview
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Brief Summary
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Peripherally inserted central catheter (PICC) are catheters that are placed mainly in the arms, but which pass in the veins to beside the heart. They are associated with occasional complications due to infection or blockage of the vein that they are in. The investigators want to investigate whether PICCs in the right arm have lower complications than those in the left. This difference in complication rates has been noticed in most other forms of central venous access.

Official Title
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Assessment of Impact of Choice of Arm for Access on Rate of Complications in Peripherally Inserted Central Venous Catheters

Conditions
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Bacterial Infections

Intervention / Treatment
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* Other: Follow up of complications


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Referral for in-patient PICC placement at centre carrying out study. Exclusion Criteria: Out of hospital referrals for PICC placement; previous PICC placement; previous long term central catheter/pacemaker; unable to give valid consent; presence of pre-existing medical preventing randomisation.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Right sided PICC placement<br>Insertion of PICC on the right arm | Other: Follow up of complications<br>* Follow up for complications leading or not to removal (occlusion, accidental removal, infection, catheter related thrombosis, leaking, pain...)<br>|
| Placebo Comparator: Left sided arm placement<br>Insertion of PICC on the left arm | Other: Follow up of complications<br>* Follow up for complications leading or not to removal (occlusion, accidental removal, infection, catheter related thrombosis, leaking, pain...)<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Line infection rate | All patients will be followed from the point of time of randomisation and PICC insertion until the line develops a complication or is removed. The average length of duration of line access in our institution is 4 weeks. | From insertion to line removal, an estimated time of 4 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Effect of number of lumens | Assessing the effect number of lumens in the catheter has on complication rate. | From insertion to time of removal, an estimated average time of four weeks. | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Catheterisation, Central Venous, Catheters, Indwelling