Manual Therapy Techniques on Cervical Spine and Psychological Interaction

Study Overview
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Brief Summary
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Manual therapy (MT) techniques applied over cervical region have over both local (neck) and distant regions (elbow) in both asymptomatic and symptomatic populations. Neurophysiological mechanisms are hypothesized to explain the underlying effects, with effects originating from peripheral mechanisms, spinal cord and supraspinal mechanisms. There is also an increasing interest in the study of the role of psychological variables in the treatment success in neck pain. Psychological variables, like anxiety catastrophizing or kinesiophobia are related to poor prognosis in the development of pain outcomes and disability in neck pain, being the Fear-Avoidance Model of pain one of the most tested models in this field.

Official Title
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Hypoalgesic Effects of Three Different Manual Therapy Techniques on Cervical Spine and Psychological Interaction: Randomized Clinical Trial

Conditions
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Neck Pain

Intervention / Treatment
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* Other: Cervical manipulation
* Other: Cervical lateral glide
* Other: Cervical mobilisation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Neck pain Exclusion Criteria: myelopathy fracture infection dystonia tumor inflammatory disease fibromyalgia or osteoporosis

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Experimental group 1<br>Cervical Manipulation | Other: Cervical manipulation<br>* The therapist cradled the subject´s head with the other hand. Gentle ipsilateral side flexion and contralateral rotation to the targeted side were introduced until slight tension was perceived in the tissues at the contact point. The High velocity, low amplitude (HVLA) manipulation was directed upward and medially in the direction of the subject´s contralateral eye. The therapist monitored for cavitation or 'popping sound' accompanying the manipulations. If an audible popping sound was not heard during the first manipulative attempt, the procedure was repeated in the second time.<br>|
| Experimental: Experimental group 2<br>Cervical lateral glide | Other: Cervical lateral glide<br>* The upper limb of the right side of subjects was maintained in rest, with the arm along the trunk and the hand over the abdominal wall. The right hand of the treating therapist was positioned over scapula region, to depress the scapula while left hand cradled the occiput and neck above C5-C6 and left hand produced a passive lateral movement of the occipital and neck region.<br>|
| Placebo Comparator: Control group<br>Cervical Mobilisation | Other: Cervical mobilisation<br>* The patients received a passive cervical mobilization that involved a grade III oscillatory unilateral posteroanterior mobilization to the right articular pillar of C5/C6 segment as described Maitland at a frequency of 2Hz. All the subjects were positioned in prone position as the protocol described by Sterling et al. for 3 sets of 2 minutes with 1 minute rest between sets.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change from Pressure Pain Thresholds (PPT) at 24 hours | PPT will be assessed bilaterally over the C7 zygapophyseal joint, epicondyle region, and trapezious muscle by an assessor blinded to the subjects condition. | 24 hours, 5 minutes after the treatment | 
| Change from State-Trait Anxiety Inventory subscale (STAI-E) at 24 hours | Will be used to measure anxiety status | 24 hours, 5 minutes after the treatment | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Beck depression Inventory (BDI-II) | Will be used to measure depression status | 24 hours, 5 minutes after the treatment | 
| Tampa Scale for Kinesiophobia | Will be used to measure Kinesiophobia status | 24 hours, 5 minutes after the treatment | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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neck pain, Manual therapy, psychological interaction