COVID-19 Critically Ill Patients' Evolution After Medical Transport by Train From Paris Intensive Care Units to West of France Intensive Care Units

Study Overview
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Brief Summary
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Since early 2020, France knows a sanitary crisis with a massive influx of COVID-19 patients admitted in Intensive Care Units (ICU). It led to a saturation of the French health system, especially in some geographic areas such as East of France or Paris region. Therefore, authorities decided to transfer some critically ill patients from these crowded ICUs to less busy regional ICUs. it was done for the first time by medical train transportation. Knowing that the investigators lack experience regarding this type of medical evacuation, regarding the high number of transferred patients, with such a logistic effort, the investigators decided to study this phase of the COVID-19 sanitary crisis in order to draw a feedback. So far, there are no data in the literature regarding this topic.

Official Title
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COVID-19 Critically Ill Patients' Evolution After Medical Transport by Train From Paris Intensive Care Units to West of France Intensive Care Units

Conditions
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COVID-19, Intensive Care Unit Syndrome

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age > 18 years COVID-19 positive patients admitted in Intensive Care Unit between 15/03/2020 and 15/04/2020 Patients (or legal representative) with no opposition to inclusion in medical research protocol Regarding case group : Patients transferred from Paris's ICU Regarding case control group : Patients admitted in ICU with no transfer from Paris Exclusion Criteria: - > 18 years under legal protection and patients with liberty restriction

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients transferred<br>Patients transferred from Paris's Intensive Care Units | |
| Patients not transferred<br>Patients admitted in Intensive Care Units with no transfer from Paris | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| number of death | to evaluate mortality | at Intensive Care Units discharge, an average of 1 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| number of infections | to evaluate morbidity | from date of admission until Intensive Care Units discharge, assessed up to 1 months | 
| number of days of mechanical ventilation |  | from date of admission until Intensive Care Units discharge, assessed up to 1 months | 
| number of days of sedation |  | from date of admission until Intensive Care Units discharge, assessed up to 1 months | 
| number of days of use of neuromuscular blocking agents |  | from date of admission until Intensive Care Units discharge, assessed up to 1 months | 
| number of days of vasopressor use |  | from date of admission until Intensive Care Units discharge, assessed up to 1 months | 
| number of days in Intensive Care Units |  | from date of admission until Intensive Care Units discharge, assessed up to 1 months | 
| number of days in hospital |  | from date of admission until hospital discharge, assessed up to 1 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Medical transport by train