EFFECT OF PRE EXTUBATION MANUAL HYPERINFLATION TECHNIQUE VS REGULAR EXTUBATION AFTER STERNOTOMY

Study Overview
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Brief Summary
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Post operative pulmonary complication (PPC) is one of the cause of mortality and morbidity after sternotomy. There is no accessible confirmation which shows the impact of Pre Extubation Manual Hyperinflation method with Regular Extubation procedure. After sternotomy manual hyperinflation technique is not taken during extubation. The objective of the study was to determine the effect of Pre Extubation Manual Hyperinflation technique VS regular Extubation technique on vitals and respiratory parameters in patients after Sternotomy.

Official Title
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Effects of Pre-extubation Manual Hyper Inflation in Comparison to Regular Extubation Following Sternotomy.

Conditions
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Sternotomy

Intervention / Treatment
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* Procedure: Extubation
* Procedure: Manual Hyperinflation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 40 to 60 Patient undergone surgery (sternotomy) Elective intubated (ETT orally) Ventilated more than 3 hours - Exclusion Criteria: Patient with any neurological issue (mentally disturbed) who cannot understand the command Complicated extubation Pulmonary pathology where lung hyperinflation was contra-indicated (e.g. acute respiratory distress syndrome, undrained pneumothorax or exacerbation of chronic obstructive pulmonary disease and acute pulmonary edema. Raised intracranial pressure Redo or reopen. -

Ages Eligible for Study
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Minimum Age: 40 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Regular Extubation<br> | Procedure: Extubation<br>* Extubation is the removal of an endotracheal tube (ETT), which is the last step in liberating a patient from the mechanical ventilator.<br>|
| Experimental: Pre Extubation Manual Hyperinflation<br> | Procedure: Extubation<br>* Extubation is the removal of an endotracheal tube (ETT), which is the last step in liberating a patient from the mechanical ventilator.<br>Procedure: Manual Hyperinflation<br>* Providing a larger tidal volume than baseline tidal volume to the patient and using a tidal volume which is 50% greater than that delivered by the ventilator<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Peak expiratory flow rate |  | 1 day | 
| Blood pH |  | 1 day | 
| Blood pO2 |  | 1 day | 
| Blood pCO2 |  | 1 day | 
| Blood pHCO3 |  | 1 day | 
| Pulse rate |  | 1 day | 
| Oxygen saturation |  | 1 day | 
| Forced expiratory volume |  | 1 day | 
| Forced vital capacity |  | 1 day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Sternotomy, Extubation, Manual Hyperinflation