Predictors of 30-day Postoperative Outcome After Elective EVAR

Study Overview
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Brief Summary
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This study investigated the 30-day postoperative outcome after elective EVAR and the role of possible predictors among patients' baseline characteristics

Detailed Description
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The study included 322 consecutive AAA patients treated electively with EVAR from March 2016 to February 2019 at a tertiary referral center. Early follow-up with clinical and laboratory evaluation took place at the 30rd day post-operatively. Any adverse event, such as major adverse cardiovascular events (MACE), post-implantation syndrome (PIS), acute kidney injury (AKI), and deaths of any cause were recorded.

Official Title
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Predictors of 30-day Postoperative Outcome After Elective Endovascular Abdominal Aortic Aneurysm Repair

Conditions
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Postoperative Complications

Intervention / Treatment
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* Other: 30-day postoperative outcome


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Only patients managed with EVAR using standard bifurcated devices in elective setting were included. Exclusion Criteria: Patients treated for ruptured, symptomatic, inflammatory or infectious AAA were excluded. Furthermore, any patient needing complex endovascular repair of the proximal landing zone was considered ineligible. Additional exclusion criteria were the presence of any trauma or surgery within two months before EVAR, any autoimmune or systemic inflammatory disease and any malignancy. Of note, any patient with clinical or laboratory signs of infection before the scheduled operation was not offered an EVAR until a complete resolution of the infection was confirmed via a clinical, laboratory and/or imaging evaluation.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| EVAR<br>Patients with AAA, treated electively by EVAR. The 30-day postoperative outcome after elective EVAR and the role of possible predictors among patients' baseline characteristics were assessed. | Other: 30-day postoperative outcome<br>* The 30-day postoperative outcome after elective EVAR and the role of possible predictors among patients' baseline characteristics were assessed<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of patients with major adverse cardiovascular events | Number of participants with major adverse cardiovascular events | 30rd day post-operatively | 
| Number of patients with acute kidney injury | Number of participants with acute kidney injury according to the RIFLE (Risk, Injury, Failure, Loss of kidney function, and End-stage kidney disease) criteria | 30rd day post-operatively | 
| Number of patients with post-implantation syndrome | Number of participants with post-implantation syndrome SIRS, without any apparent sign of infection | 30rd day post-operatively | 
| Deaths of any cause | Number of participants who died from any cause | 30rd day post-operatively |