Uterine Rupture During Labor Among Women With a Prior Cesarean Delivery

Study Overview
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Brief Summary
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Although a rare event, uterine rupture during labour is one of the most serious obstetric complications because of the dramatic maternal-fetal consequences that can result. Identifying the risk factors associated with uterine rupture would enable gynecologists to provide patients with risks of uterine rupture in the event of attempted vaginal delivery. The aim of our study is to determine risks factors for uterine rupture during labour in patients with a previous cesarean delivery who have not given birth since and to assess the occurrence of maternal-fetal comply-cations compared to patients with a previous cesarean delivery without uterine rupture.

Official Title
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Uterine Rupture During Labor Among Women With a Prior Cesarean Delivery : Risks Factors, Maternal and Perinatal Outcomes

Conditions
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Uterine Rupture, Mode of Delivery

Intervention / Treatment
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* Other: Risks factors, maternal and neonatal outcomes/complications


Participation Criteria
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Eligibility Criteria
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Inclusion criteria: Singleton pregnancy > 24 weeks of gestation Second or multiparous with a previous cesarean section without vaginal delivery since Cephalic presentation or completed breech Uterine rupture during labor Exclusion criteria: Incomplete uterine rupture Multiple gestation Transverse presentation or complete breech Vaginal delivery after cesarean Non-low transverse cesarean section Placenta praevia Antepartum intrauterine fetal death History of uterine surgery (myomectomy)

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Women with uterine rupture<br>Women with uterine rupture | |
| Women without uterine rupture<br>Women without uterine rupture | Other: Risks factors, maternal and neonatal outcomes/complications<br>* Risks factors, maternal and neonatal outcomes/complications<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Assess the risks factors of uterine rupture | Assess the risks factors of uterine rupture Assess the risks factors of uterine rupture using obstetric measures | 1 day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of Participants with Assess the maternal and perinatal complications and outcomes | Number of Participants withAssess the maternal and perinatal complications and outcomes : looking for maternal complications (chorioamnionitis , transfusion, post-partum hemorrhage, surgery for blad-der wound, maternal death,…) and neonatal comply-cations (apgar<7 at 5minutes, pH <7,15, neonatal intein-sive care unit and perinatal death) | 1 day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Risks factors, Uterine rupture after a previous cesarean delivery, Vaginal birth after cesarean, Prior cesarean, Perinatal outcome