Zero to Five Automated Oscillometric Office Blood Pressure (AOBP) Measurement

Study Overview
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Brief Summary
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The Hypertension Canada Clinical Practice Guidelines for blood pressure measurement using AOBP recommend against any wait time prior to commencing the measurement. The recent AHA guidelines however call for a 5-minute rest first. In uncontrolled hypertension, AOBP is typically higher than the daytime readings from ambulatory blood pressure monitoring (ABPM), but this is not the case for patients with controlled hypertension.

Detailed Description
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Objective: Does a 5 minute rest or no rest before measurement using AOBP provide the most accurate reading in patients with controlled and uncontrolled hypertension, and in patients with white coat hypertension compared to daytime ABPM? Implications: Through this study, we hope to: (i) Advance the understanding of the role of AOBP in measuring blood pressure. (ii) Determine whether a 5-minute rest, or no rest at all is needed prior to AOBP measurement. (iii) Assess the relationship of AOBP to daytime ABPM for patient with controlled and uncontrolled hypertension and in patients with white coat hypertension.

Official Title
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Zero to Five Automated Oscillometric Office Blood Pressure (AOBP) Measurement: the Impact of a 5 Minute Rest Time on AOBP Measurement

Conditions
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Hypertension, Cardiovascular Diseases

Intervention / Treatment
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* Diagnostic Test: Zero to Five Automated Oscillometric Office Blood Pressure (AOBP) Measurement


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 18 years or older Referred for ABPM Written informed consent Exclusion Criteria: Unable to perform AOBP or ABPM for some reason

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Five minute rest<br> | Diagnostic Test: Zero to Five Automated Oscillometric Office Blood Pressure (AOBP) Measurement<br>* To compare the difference between the daytime ABPM and AOBP with zero or five minutes wait time.<br>|
| Active Comparator: Zero minute rest<br> | Diagnostic Test: Zero to Five Automated Oscillometric Office Blood Pressure (AOBP) Measurement<br>* To compare the difference between the daytime ABPM and AOBP with zero or five minutes wait time.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Difference in systolic and diastolic BP in patients randomized to zero or five minutes wait before the AOBP measurement. | difference in blood pressure | 4 months - 1 yr | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Difference in systolic and diastolic BP between the AOBP and daytime ABPM in patients randomized to zero or five minutes wait before the AOBP measurement. | difference in blood pressure | 4 months - 1yr |