Quantification of Silicone Oil Emulsification After Pars Plana Vitrectomy

Study Overview
=================
Brief Summary
-----------------
silicone oil tamponade removal after previous injection of complicated retinal detachment can be achieved with active suction followed by triple air-fluid exchange or prolonged lavage of the vitreous chamber to remove emulsification. Purpose of the study is to compare the amount of silicone oil emulsification droplets within the lavage fluid in case of air exchange and simple lavage to compare which technique removed the highest percentage of emulsion. This is achieved by comparing consecutive samples of lavage fluid

Detailed Description
-----------------
silicone oil tamponade removal after previous injection of complicated retinal detachment can be achieved with active suction followed by triple air-fluid exchange or prolonged lavage of the vitreous chamber to remove emulsification. Purpose of the study is to compare the amount of silicone oil emulsification droplets within the lavage fluid in case of air exchange and simple lavage to compare which technique removed the highest percentage of emulsion. This is achieved by comparing consecutive samples of lavage fluid. Therefore consecutive patients scheduled to SiO removal with triple air exchange or vitreous chamber lavage are enrolled and 3 samples of intraocular fluid aspirated during the fluid exchange procedure sent to the lab for SiO emulsion count and quantification.

Official Title
-----------------
Quantification of Silicone Oil Emulsification After Pars Plana Vitrectomy

Conditions
-----------------
PArs Plana Vitrectomy, Retinal Detachment, Silicone Oil Droplets on Intraocular Lens

Intervention / Treatment
-----------------
* Procedure: pars plana vitrectomy


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: previous silicone oil tamponade after pars plana vitrectomy age >18 years Attached retina Exclusion Criteria: unwilling or unable to participate, previous multiple eye surgery History of Trauma

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| triple air fluid exchange<br>those undergoing triple air fluid exchange | Procedure: pars plana vitrectomy<br>* silicone oil active aspiration and isovolumetric BSS replacement followed by irrigation and /o gas fluid exchange<br>|
| irrigation<br>those undergoing vitreous chamber irrigation with comparable volume of BSS | Procedure: pars plana vitrectomy<br>* silicone oil active aspiration and isovolumetric BSS replacement followed by irrigation and /o gas fluid exchange<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| number of silicone oil emulsification droplets per volume unit | number of silicone oil emulsification droplets per volume unit. Fluid taken from the vitreous chamber during surgery is subsequently analyzed. Therefore time frame is just one: after taking all samples they are analyzed to count oil droplets per volume unit | 6 months after primary surgery |