Unilateral Sequential Sympathectomy for Palmar Hyperhidrosis

Study Overview
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Brief Summary
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Comparison between unilateral sequential and bilateral simultaneous endoscopic thoracic sympathectomy for palmar hyperhidrosis on patients outcomes notably compensatory hyperhidrosis.

Official Title
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Unilateral Sequential Versus Bilateral Simultaneous Sympathectomy for Palmar Hyperhidrosis: a Study of 407 Cases.

Conditions
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Palmar Hyperhidrosis

Intervention / Treatment
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* Procedure: bilateral simultaneous endoscopic thoracic symapthectomy
* Procedure: unilateral sequential endoscopic thoracic symapthectomy.


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients suffering palmar hyperhidrosis Exclusion Criteria: Patients with pleural adhesions, bleeding diathesis, local infection or previous operation for hyperhidrosis

Ages Eligible for Study
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Minimum Age: 8 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: B-ETS<br>Bilateral simultaneous endoscopic thoracic sympathectomy: bilateral simultaneous T2-T3 ganglionectomy. | Procedure: bilateral simultaneous endoscopic thoracic symapthectomy<br>* Patients underwent bilateral simultaneous T2-T3 ganglionectomy using thoracoscopic approach.<br>|
| Active Comparator: S-ETS<br>unilateral sequential endoscopic thoracic sympathectomy: unilateral T2-T3 ganglionectomy of the dominant side followed by T2-T3 ganglionectomy of the other side after 2 months interval | Procedure: unilateral sequential endoscopic thoracic symapthectomy.<br>* Patients underwent unilateral T2-T3 ganglionectomy of the dominant side followed by T2-T3 ganglionectomy of the other side after 2 months interval.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of participants developing compensatory hyperhidrosis (reflex sweating) following sympathectomy. | Number pf patients developing compensatory hyperhidrosis (reflex sweating) following sympathectomy. Compensatory hyperhidrosis was graded as severe when the patient mentioned that sweating interfered with his or her normal activity, moderate when the patient indicated that his or her sweating was not bothersome and mild when the patient did not mention dampness or made only a brief reference. | one year | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of patients who will be satisfied or unsatisfied regarding the procedure. | we measure patient satisfaction regarding the procedure by asking the patients to rate their level of satisfaction as very satisfied, somewhat satisfied, somewhat dissatisfied and very dissatisfied. Patients were considered satisfied if they reported being very satisfied or somewhat satisfied. | one year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Palmar hyperhidrosis, Endoscopic thoracic sympathectomy