linjc16/ctgov huggingface dataset:
Syncope Prediction Study

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to perform a prospective evaluation of the vasovagal syncope prediction algorithm, called Tilt Test Analyzer, during head up tilt testing tests in one center in the United Kingdom.

Detailed Description
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Vasovagal syncope (VVS) is a form of neurally-mediated reflex syncope, which is marked by a sudden fall in blood pressure with an associated fall in heart rate often resulting in syncope, head-up tilt (HUT) testing is commonly used to bring information about VVS using ECG and blood pressure monitoring with medical observation. We developed an algorithm, called Tilt Test Analyzer, to predict VVS during HUT based on the simultaneous analysis of heart rate (RR interval), systolic blood pressure (SBP) and an indicator of autonomic modulation represented by heart rate and blood pressure variability (HRV and BPV). The primary objective of this study is to evaluate the VVS prediction algorithm in a prospective cohort of patients in the tilt laboratory The primary endpoint is the VVS prediction algorithm performance by means of measuring the sensitivity and specificity values. The study is designed to test if the prospective analysis of tilt-test patients can reproduce the results previously obtained in the published retrospective analysis on 1155 patients with a similar clinically relevant sensitivity and specificity.

Official Title
-----------------
Syncope Prediction Study

Conditions
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Vasovagal Syncope

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients referred to the center with vasovagal syncope for tilt testing. The patient is willing and able to cooperate with the study procedures. The subject or legal guardian is able to provide written informed consent Exclusion Criteria: Patients under 18 years or over 90 years old. Women who are currently pregnant or have a positive pregnancy test. Patients who had a prior tilt test. Patients enrolled in another device or drug study.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 90 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Syncope Prediction<br>All enrolled patients that performed the tilt table test | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Sensitivity of the Syncope Prediction Algorithm | Number of tilt-positive participants predicted in the right way by the syncope prediction algorithm | Tilt Test with average duration of 1 hour | 
| Specificity of the Syncope Prediction Algorithm | Number of tilt-negative participants identified as negative by the syncope prediction algorithm | Tilt Test with average duration of 1 hour |
Can Vibration Stimulation of the Foot Sole Activate Leg Muscles?

Study Overview
=================
Brief Summary
-----------------
Participants will be asked to complete three different tests (standing, stepping and assisted walking) and will experience three different experimental conditions during each test. The three conditions are types of vibratory plantar cutaneous stimulation, which include no vibratory stimulation, submaximal vibratory stimulation and supramaximal vibratory stimulation. In the first condition, participants will experience no stimulation applied to any part of the body. In the second condition, a submaximal vibratory stimulus will be delivered at 90% of the participant's threshold to the surface of the foot. In the third condition, a supramaximal vibratory stimulus will be delivered at three times the participant's threshold. The hypothesis is that this plantar stimulation (90% threshold and supramaximal) will elicit increased muscle activity during these tests. If the hypothesis is positive then this protocol will also be presented in incomplete spinal cord injuried participants.

Official Title
-----------------
Plantar Cutaneous Stimulation Used to Elicit Muscle Activity in Individuals With Incomplete Spinal Cord Injury

Conditions
-----------------
Spinal Cord Injury

Intervention / Treatment
-----------------
* Other: plantar vibration


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: no spinal cord injury Exclusion Criteria: any musculoskeletal or neurological disease that affects movement or balance

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 45 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: spinal cord injury<br>Individuals who have sustained an incomplete spinal cord injury | Other: plantar vibration<br> <br> |
| Active Comparator: non-spinal cord injury<br>Individuals who have not sustained a spinal cord injury | Other: plantar vibration<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Muscle activity | Muscle activity will be measured by electromyography equipment (two electrodes placed on the muscle belly) and then the outcome measures will be the description of both the timing (relative to task onset) and magintude of muscle activity. | up to 2 months after experiment |
Emergency Department Home Blood Pressure Monitoring and BpTRU Study

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to evaluate the Congruence of Emergency Department (ED) Attendings' Predictions of Hypertension with Results of Home Blood Pressure Monitoring.

Detailed Description
-----------------
Evaluate the Congruence of Emergency Department (ED) Attendings' Predictions of Hypertension with Results of Home Blood Pressure Monitoring & evaluate reliability of ED measured elevated blood pressure compared to the BpTRU

Official Title
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Congruence of Emergency Department Attendings' Predictions of Hypertension With Results of Home Blood Pressure Monitoring

Conditions
-----------------
Hypertension

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: One elevated blood pressure greater than 120 systolic and/or 80 diastolic BpTRU device blood pressure greater than 120 systolic and/or 80 diastolic while in ED Exclusion Criteria: Prior history of hypertension Currently on antihypertensives or receiving prescription on discharge Pregnancy History of atrial fibrillation Dialysis patient Nursing home or rehabilitation center resident Admitted Moving out of the area in next 30 days Substance abuse Prisoner Presenting for psychiatric complaint requiring constant observation Inability to give informed consent (intoxicated, altered, non-English speaking) Presenting with symptoms of hypertensive emergency Inability to demonstrate adequate use of the home blood pressure device in the ED Arm circumference less than 9 inches or greater than 17 inches

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Prehypertension<br>Using the JNC7 definition | |
| Stage I Hypertension<br>Using the JNC7 definition | |
| Stage II Hypertension<br>Using the JNC7 definition | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The percentage of emergency department attendings that accurately predict which patients meet criteria for hypertension in two week follow-up using home blood pressure monitoring. |  | 18 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The predictive value of the emergency department measured blood pressure by the standard ED blood pressure device, BpTRU device, and home blood pressure device for hypertension in follow-up |  | 18 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
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Emergency Medical Services, Emergency Care, Hypertension, BpTRU, Blood pressure
Determination of Voiding Patterns of Children With Vesicoureteral Reflux

Study Overview
=================
Brief Summary
-----------------
Determine if the pattern of voiding differs in children with vesicoureteral reflux (VUR) compared to those who do not have VUR.

Detailed Description
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We hope to determine the statistical difference between the flow rate and volume of urination in children with VUR compared to those without.

Official Title
-----------------
Determination of Voiding Patterns of Children With Vesicoureteral Reflux

Conditions
-----------------
Vesicoureteral Reflux

Participation Criteria
=================
Eligibility Criteria
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Inclusion Criteria: Children with or without vesicoureteral reflux (history of VUR) Toilet trained and can void on command Exclusion Criteria: Any voiding disorder, musculoskeletal neurologic disorders, other congenital or acquired genitourinary problems, growth disorders, recent UTI

Ages Eligible for Study
-----------------
Minimum Age: 3 Years
Maximum Age: 16 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Uroflow rate | Obtain pre and postoperative uroflow after VUR correction | 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| PVR | Pre and postoperative measures | 3 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
voiding patterns, flow rate, ultrasound
A Retrospective Pharmacoeconomic Study of Lung Cancer

Study Overview
=================
Brief Summary
-----------------
Lung cancer is the No. cause of cancer death in Taiwan. Yet most of lung cancer are diagnosed at late stage, not amenable to surgical resection. With the introduction of new targeted agents, such as EGFR tyrosine kinase inhibitors and the identification of EGFR mutations, lung cancer management has markedly changed in recent years. However, these new agents are costly and their payment is restricted in certain situations defined National Insurance Agency. Therefore, using databases from National Insurance Agency might not be able to reflect the exact impact on pharmacoeconomics. In this study, the investigators will analyze the data from a tertiary medical center, where all the costs including insurance reimbursement, co-payment, and payment not covered by insurance. The investigators will also compare with the investigators results with national database to analyze the cost benefit of these new agents on lung cancer.

Official Title
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A Retrospective Pharmacoeconomic Study of Lung Cancer in Wan-Fang Hospital

Conditions
-----------------
Lung Cancer

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: lung cancer patients in WanFang Hospital Exclusion Criteria: non
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
lung cancer, pharmacoeconomics, new agents
The Relationship Between Operative and Radiologic Stem Version

Study Overview
=================
Brief Summary
-----------------
Investigators prospectively evaluate the accuracy of intraoperative stem anteversion in 40consecutive total hip arthroplasties.

Detailed Description
-----------------
In all hips, investigators measure femoral stem anteversion postoperatively with three-dimensional computed tomography reconstruction of the femur, using both the distal femoral epicondyles and the posterior femoral condyles to determine the femoral diaphyseal plane. And investigators compare the surgeon's estimate of intraoperative stem version and stem version of CT scan.

Official Title
-----------------
The Relationship Between Operative and Radiologic Stem Version : Which Factors Influence Resultant Stem Version in Primary Total Hip Arthroplasty

Conditions
-----------------
Arthroplasty Total Hip Replacement

Intervention / Treatment
-----------------
* Radiation: The Relationship Between Operative and Radiologic Stem Version


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Investigators recruited 40 consecutive patients who underwent THR between October 2015 and December 2015 Exclusion Criteria: patients who could not extend the hip because of a residual flexion contracture. who had a flexion contracture of the knee or who could not flex the hip to 90° even after THR were excluded because participants could not adopt the posture required for the particular radiographs and CT scans.
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| stem anteversion<br>intraoperative surgeon's estimation and postopertive CT sacn were taken to measure stem anteversion | Radiation: The Relationship Between Operative and Radiologic Stem Version<br>* intraopertive surgeon's estimation and postoperative CT scan<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Intraopertive surgeon's estimation and postoperative CT scan were taken to measure stem anteversion |  | postoperative 4days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The correlation between stem anteversion of intraopertive surgeon's estimation and stem version postoperative CT scan | to determine ICC(intraclass coefficient, correlation coefficient) | postoperative 4days |
Does Bariatric Surgery Changes Eating Habits and Addiction in Morbid Obesity?

Study Overview
=================
Brief Summary
-----------------
Obesity is a big health problem worldwide. Mostly obese people have food addiction and bad eating habits. Bariatric surgery is a good alternative for patients who failed to loose weight with other measures like behavioral changes, activities and sports, diet, etc.. The investigators know the changes occurred after surgery in eating habits due to restrictive and malabsorptive feature of the surgery performed. There is no study in the literature to measure these changes. The investigators will try to detect these kind of behavioral changes by a survey before and after surgery.

Official Title
-----------------
Study of Eating Habits and Addiction Changes in Short and Long Time Follow-up in Morbidly Obese Patients Who Undergo Bariatric Surgery.

Conditions
-----------------
Obesity

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with BMI > 40 kg/m2 Patients with BMI > 35 kg7m2 < 40 kg/m2 but with comorbidity Patients > 18 years old Patients who sign the inform consent Patients who have no psychiatric disease Patients who have no endocrine disorders Exclusion Criteria: All obese patients who do not fulfill the criteria above mentioned

Ages Eligible for Study
-----------------
Minimum Age: 19 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Obesity, Bariatric surgery, Behavioral changes, Eating habits, Eating addiction
Prevalence of Spasticity in Adults With Mental Retardation Living in the Community

Study Overview
=================
Brief Summary
-----------------
This survey aims to investigate the prevalence of spasticity among adults who live in community settings in Davidson County, Tennessee. The treatment of spasticity in those who live in community homes could significantly increase a person's quality of life by allowing them to participate more independently in activities of daily living, or by making assistance easier for caregivers.

Detailed Description
-----------------
The process of deinstitutionalization has transitioned a large majority of persons with developmental disabilities into the community over the past several decades, and that number will only increase going forward. There are 926 people in this region who are provided assistance through the Division of Mental Retardation Services (DMRS). People with developmental disabilities frequently have comorbidities such as spasticity that hinder their ability to participate in activities of daily living. Spasticity results from brain or spinal cord injury and can produce increased muscle tone, causing joint stiffness, contractures and pain that can interfere with recommended treatment. A previous survey conducted at Clover Bottom Developmental Center investigated care areas typically affected by spasticity, including splinting, hygiene, dressing, transfers, positioning, ambulation, and engaging in other functional activities. Pfister et al. reported the prevalence of spasticity in the developmental center to be 35% (72/205); of those people, the Survey Physician felt that 75% (54/72) would achieve a functional benefit from treatment. Primary endpoints will assess the prevalence of spasticity in adults who reside in the community, and whether or not spasticity impacts activities of daily living. When appropriate, potential care area goals will be identified, and treatment options will be recorded. Secondary endpoints will examine whether or not participants currently receive treatment for spasticity; if so, what treatment is being used; and which care areas are most impacted by spasticity.

Official Title
-----------------
Prevalence of Spasticity in Adults With Mental Retardation Residing in a Community Setting

Conditions
-----------------
Mental Retardation, Spasticity

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Adult (18 and over) with mental retardation Living in a community home in Davidson County, Tennessee. Exclusion Criteria: None.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
spasticity, mental retardation
Comparison of LASIK and SBK

Study Overview
=================
Brief Summary
-----------------
The objective of the study is to compare clinical outcomes from LASIK and SBK using FDA-approved laser technology on the same patient

Detailed Description
-----------------
Patients undergoing bilateral refractive surgery on the same day will have one eye randomized to LASIK and the fellow eye assigned to SBK treatment.

Official Title
-----------------
Comparison of Laser-Assisted in Situ Keratomeleusis (LASIK) vs Sub-Bowman's Keratomileusis (SBK): Assessment of Visual Function and Patient Satisfaction

Conditions
-----------------
Myopia

Intervention / Treatment
-----------------
* Procedure: LASIK
* Procedure: SBK


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients deemed to be suitable candidates for bilateral LASIK surgery Exclusion Criteria: Patients who desire monovision correction rather than bilateral distance correction

Ages Eligible for Study
-----------------
Minimum Age: 21 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: 1<br>LASIK | Procedure: LASIK<br>* Refractive surgery<br>|
| Active Comparator: 2<br>SBK | Procedure: SBK<br>* Refractive surgery<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual acuity |  | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Manifest refraction |  | 6 months | 
| Wavefront aberration value |  | 6 months |