Clinical Comparison of Universal Adhesives in Terms of Different Application Modes on the Restoration of NCCLs

Study Overview
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Brief Summary
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The aim of this randomized, controlled, prospective clinical trial is to evaluate the performances of two different universal adhesives and an etch&rinse adhesive in restoration of non-caries cervical lesions. Twenty patients will receive restorations. Lesions will be divided into 7 groups according to adhesive systems and application modes: GSE: Gluma Universal- self etch, GSL: Gluma Universal-selective etching, GER: Gluma Universal-etch&rinse, ASE: All Bond Universal- self etch, ASL: All Bond Universal- selective etching, AER: All Bond Universal- etch&rinse, SB (Control): Single Bond2+etch&rinse. Restorations (nano-hybrid composite) will be scored with regard to retention, marginal discoloration, marginal adaptation, recurrent caries and post operative sensitivity using modified USPHS criteria after 48 months. Two examiners who is not involved in the placement of restorations will conduct the evaluations. Descriptive statistics will be performed using Chi-square tests.

Official Title
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Clinical Comparison of Universal Adhesives in Terms of Different Application Modes on the Restoration of NCCLs

Conditions
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Tooth Wear

Intervention / Treatment
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* Device: Gluma Universal
* Device: All Bond Universal
* Drug: Single Bond2


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Inclusion criteria will be as follows: being 18 years or older, having no medical or behavioral problems preventing then from attending review visits, having at least 7 tooth with NCCLs (d) having antagonist teeth. Exclusion Criteria: Exlusion criteria will be: poor gingival health, uncontrolled, rampant caries, bruxism, removable partial dentures, xerostomia.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Gluma Universal, self-etch mode (GSE)<br> | Device: Gluma Universal<br>* Adhesive systems<br>|
| Experimental: Gluma Universal, selective etching (GSL)<br> | Device: Gluma Universal<br>* Adhesive systems<br>|
| Experimental: Gluma Universal, etch&rinse (GER)<br> | Device: Gluma Universal<br>* Adhesive systems<br>|
| Experimental: All Bond Universal, self-etch (ASE)<br> | Device: All Bond Universal<br>* Adhesive systems<br>|
| Experimental: All Bond Universal, selective etching (ASL)<br> | Device: All Bond Universal<br>* Adhesive systems<br>|
| Experimental: All Bond Universal, etch&rinse (AER)<br> | Device: All Bond Universal<br>* Adhesive systems<br>|
| Experimental: Single Bond2, etch&rinse (SBU)<br> | Drug: Single Bond2<br>* Adhesive systems<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Clinical performances of different adhesives | Two year examinations according to USPHS criteria | Two years |