linjc16/ctgov huggingface dataset:
Peer Mentoring for Persons With Spinal Cord Injury (SCI)

Study Overview
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Brief Summary
-----------------
A peer mentoring program for persons with SCI was developed. Individuals who experienced SCI in the past and have adapted well functionally were asked to serve as mentors for individuals with newly-acquired SCI. These individuals undergo volunteer and peer mentoring training prior to mentoring activities. They are a subset of the study participants. We are tracking their satisfaction with life, positive and negative affect, life adjustment, depression, and social support over time. We hypothesize that measures of adjustment will become more positive as involvement as a mentor increases. The second subset of study participants are the individuals with newly-acquired SCI. They complete a baseline assessment of the measures listed above and then at 6 months, one year, and two years after match with a mentor. We also collect information about the quantity and quality of the mentoring sessions from both the mentor and mentee. We hypothesize that the mentee's adjustment will be positively influenced by the number and quality of the mentoring sessions. Due to the relatively small number of SCI per year in our program, we opted to offer the mentoring program to all individuals with newly acquired SCI, thus there is no control group.

Official Title
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Peer Mentoring for Persons With Spinal Cord Injury: Program Satisfaction and Outcome for Mentor/Mentee

Conditions
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Spinal Cord Injury

Intervention / Treatment
-----------------
* Behavioral: peer mentoring


Participation Criteria
=================
Eligibility Criteria
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Inclusion Criteria: experienced a SCI Exclusion Criteria: no severe traumatic brain injury no severe psychiatric disturbance

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
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No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Behavioral: peer mentoring|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| satisfaction with life, positive and negative affect, life adjustment, depression, and social support |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| is the mentee's adjustment positively influenced by the number and quality of the mentoring sessions |  |  |
Urine Sample Processing Study

Study Overview
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Brief Summary
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The objective of the study is to collect and process urine samples from Intensive Care Unit (ICU) subjects with moderate to severe (Stage 2 or 3) acute kidney injury (AKI) for use in assessing the effects of urine sample freezing and various storage conditions on NEPHROCLEAR™ CCL14 Test results. This study is observational and will have no impact on the medical management of the subject.

Official Title
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Urine Sample Processing Study: Analysis of Fresh Versus Frozen Urine Samples From ICU Subjects

Conditions
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Acute Kidney Injury

Intervention / Treatment
-----------------
* Diagnostic Test: Urine collection for NEPHROCLEAR CCL14 Test


Participation Criteria
=================
Eligibility Criteria
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Inclusion Criteria: Males and females 21 years of age or older; Receiving care in an intensive care unit; Expected to remain in the ICU for at least 48 hours after enrollment; Use of indwelling urinary catheter as standard care at the time of enrollment; Subject must have acute kidney injury (KDIGO Stage 2 or Stage 3) at the time of sample collection; Urine sample must be collected within 36 hours of meeting KDIGO Stage 2 criteria; Written informed consent provided by patient or legally authorized representative (LAR). Exclusion Criteria: Prior kidney transplantation; Comfort-measures-only status; Already receiving dialysis (either acute or chronic) or in imminent need of dialysis at the time of enrollment; Known infection with human immunodeficiency virus (HIV) or active hepatitis (acute or chronic); Special populations, pregnant women, prisoners or institutionalized individuals.

Ages Eligible for Study
-----------------
Minimum Age: 21 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients with KDIGO stage 2 or 3 AKI<br> | Diagnostic Test: Urine collection for NEPHROCLEAR CCL14 Test<br>* Urine will be collected for analysis with the NEPHROCLEAR CCL14 Test<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Stability of CCL14 in urine samples | Stability of CCL14 in urine samples as measured by the NEPHROCLEAR™ CCL14 Test | Up to 24 hours |
Capacity to Consent in Acutely Intoxicated Emergency Department Patients

Study Overview
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Brief Summary
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The ability to meaningfully consent intoxicated and chemically dependent patients for research has inhibited medical advances in this vulnerable population. A recent pilot supported use of the University of California, San Diego Brief Assessment of Capacity to Consent tool to assess the capacity of intoxicated emergency department patients to participate in research. The objective is to determine the number of intoxicated emergency department patients who could correctly complete the questionnaire, and evaluate alcohol concentration, sedation and ability to recall participation upon sobriety.

Official Title
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The University of California, San Diego Brief Assessment of Capacity to Consent Instrument in Acutely Intoxicated Emergency Department Patients

Conditions
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Informed Consent

Intervention / Treatment
-----------------
* Other: University of California, San Diego Brief Assessment of Capacity to Consent Tool


Participation Criteria
=================
Eligibility Criteria
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Inclusion Criteria: 18 years or older, intoxicated with alcohol Exclusion Criteria: intoxication was due to a substance other than ethanol (negative breath alcohol concentration), refusal to participate, excessive agitation, or if the treating physician deemed the patient medically or psychologically unstable. Patients were also excluded if they had previously been enrolled in the study

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: University of California, San Diego Brief Assessment of Capacity to Consent Tool|Non-pregnant, English speaking patients older than 18 with evidence of acute alcohol intoxication were considered eligible for participation. Patients were asked to complete the 10 question tool on arrival to the emergency department. Patie|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The number of intoxicated emergency department patients who could correctly complete the questionnaire |  | Immediately | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Alcohol concentration (breath or serum) |  | Immediately | 
| Degree of sedation | Observer's Assessment of Alertness/Sedation scale (OAA/S) score | Immediately | 
| Recall of participation |  | Between 2 and 12 hours after initial enrollment, depending on the time clinical sobriety achived | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
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alcohol
Measurements of Sexual Steroids' Concentrations in Prostatic Tissue

Study Overview
=================
Brief Summary
-----------------
In the investigators's previous work, measurements of intra-prostatic concentrations of sex steroids were determined on samples taken from the operating room using a punch. In order to study the in-vivo intra-prostatic concentrations of sex steroid, it is necessary to validate a measurement technique performed on samples obtained by a biopsy needle used in standard care for prostate biopsy punctures allowing the diagnosis and follow-up of prostate cancer. The aim of this project is to validate this measurement technique carried out on samples obtained by the biopsy needle and to define the optimal number of carrots obtained by biopsy offering dosage results comparable to the punch.

Official Title
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Measurements of Sexual Steroids' Concentrations in Prostatic Tissue From Samples Taken by Biopsy Needle on Fresh Operating Parts : Measurements' Reliability

Conditions
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Bladder Cancer

Participation Criteria
=================
Eligibility Criteria
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Inclusion Criteria: Patient aged ≥ 18 years With a bladder cancer Should be operated by total cystoprostatectomy at Foch Hospital Affiliated to a health insurance scheme Having expressed the non-opposition for the participation to the study Exclusion Criteria: Patient receiving or has received a treatment by analog or antagonist of Luteinizing Hormone Releasing Hormone (LHRH), antiandrogens (steroidal or non-steroidal), 5 alpha-reductase inhibitor, docetaxel or cabazitaxel chemotherapy, abiraterone acetate, enzalutamide or corticosteroids Patient who does not understand French Patient deprived of liberty or under guardianship

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
Male

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Intra-prostatic concentrations of sex steroids | To compare intra-prostatic concentrations of sex steroids on samples taken by punch (reference technique) and by an increasing number (1 to 3 carrots) of samples taken by biopsy needle (experimental technique) on fresh surgical specimen. | Day 0 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Steroids' concentrations, Biopsy needle, Cystoprostatectomy
Evaluation of Screening for Visual Disorders of the Old Subject in Consultation Memory

Study Overview
=================
Brief Summary
-----------------
Visual disorders are often overlooked in the treatment of cognitive disorders of the elderly. Yet the visual deficit impacts the quality of life, the evolution of the autonomy and psycho-behavioral disorders in cognitive diseases. The main objective of the study is to evaluate the prevalence of visual disorders among elderly patients at consultant outpatient center of Nantes clinical gerontology as part of the consultation geriatric memory. Secondary objectives are to describe ophthalmological diseases detected and taken into the proposed ophthalmic load, to determine if there are associations between eye diseases and cognitive disorders, to estimate the proportion of patients who may have an ophthalmologic evaluation to determine the cognitive profiles and geriatric evaluation and ocular pathological, depending on the assessment of arterial stiffness. The results of this study will build a testing strategy to promote access of older patients with cognitive impairment to vision care.

Official Title
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Evaluation of Screening for Visual Disorders of the Old Subject in Consultation Memory

Conditions
-----------------
Visual Disorders

Intervention / Treatment
-----------------
* Other: Non interventional study


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Elderly over 65 years, Subject to consultation from memory Clinical Gerontology ambulatory center Nantes University Hospital Current use of spoken French Patient (or legal guardian, if applicable) has given its written consent Patient affiliated to a social security scheme Exclusion Criteria: Life expectancy lower 1 year Mobility limitation preventing the installation retinal Major disorders and productive behavior does not allow participation in diagnostic procedures. Inability to respond to instructions when performing ophthalmological examinations.

Ages Eligible for Study
-----------------
Minimum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: Non interventional study|Patients agreeing to participate in the study will have a cognitive assessment and geriatric assessment, carried out according to usual practices and grids clinical gerontology cluster. They will benefit in addition to a noninvasive screening and risk-free ophthalmic (visual acuity, intraocular pressure, examination of the eyelids and fundus).|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of participants with presence of an ophthalmological disease (symptomatic or not) after clinical evaluation. |  | 6 month |
Exposure to Chemical Substances Within Household Waste Incineration Plants

Study Overview
=================
Brief Summary
-----------------
Employees of household waste incineration plants (UIOM) are exposed to multiple chemical substances that can pose a risk to their health. The studies carried out find increases in certain toxic chemicals (heavy metals, dioxins), in the biological fluids of employees (blood, urine), in particular before the 2000s Another study conducted by Tait finds potential organic alterations.The investigators wish to complete the dissertation work with, in particular, an analysis of the quantitative elements of the exposure assessment (metrologies and biometrologies)

Detailed Description
-----------------
The aim of the study is to evaluate the recorded chemical exposures of certain employees of a household waste incineration plant (UIOM) in order to deduce the risk to their health.

Official Title
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Evaluation of the Exposure to Chemical Substances of Some of the Employees Working in a Household Waste Incineration Plant

Conditions
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Exposure to Chemical Pollution, Occupational

Participation Criteria
=================
Eligibility Criteria
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Inclusion criteria: Major subject (≥18 years old) Subject currently working, or having worked in the Strasbourg waste incineration plant between 01/01/2013 and 01/09/2022 within the maintenance or operating team Subject not objecting, after being informed, to the reuse of their data for the purposes of this research Subject in whom one or more biometrologies (blood lead level measurement, urinary cadmium level measurement, urinary 1-hydroxypyrene level measurement) were performed Exclusion criteria: -Subject who expressed their opposition to participating in the study

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Retrospective evaluation of the identified chemical exposures of certain employees of a household waste incineration plant (UIOM) in order to deduce the risk to their health. | The study is based on a retrospective analysis of existing data in the files of patients treated by the occupational medicine department | Files analysed retrospectively from 01 January 2013 to 01 September 2022 will be examined | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
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Chemical Pollution
Abnormal Expression Proteins, Mitochondrial DNA and miRNA of Irritable Bowel Syndrome

Study Overview
=================
Brief Summary
-----------------
In the investigators study, the investigators will focus on the screening of the related proteins and miRNA to IBS in order to reveal the possible clues or molecular mechanism for this disorder.

Detailed Description
-----------------
For the proteomic procedures, Our study groups extracted proteins from the cecum and sigmoid colon samples and ran on the two-dimensional gel electrophoresis (2-DE). The proteins on 2-DE were visualized by the silver stain, and then gel maps were scanned and analyzed with the Image Master 2D Elite. The obvious abnormal protein spots were identified by the mass spectrometry. Western blot 、 immunohistochemistry 、 mRNA and miRNA were also performed for further verification of the proteins.

Official Title
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Screening and Identification of Abnormal Expression Proteins and miRNA From Colonic Mucosa of Patients With Irritable Bowel Syndrome.

Conditions
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Irritable Bowel Syndrome, Digestive System Diseases, Gastrointestinal Diseases, Intestinal Diseases, Colonic Diseases, Colonic Diseases, Functional

Participation Criteria
=================
Eligibility Criteria
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Inclusion Criteria: Patients with symptoms meeting Rome III criteria for diagnosis of IBS-C and IBS-D Exclusion Criteria: Patients with organic illnesses or a history of major abdominal surgery Major psychotic episode, mental retardation or dementia Pregnant women and lactational women Postinfectious IBS, PI-IBS

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 60 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
IBS, proteomics, fluorescent quantitation polymerase chain reaction, Western blot, immunohistochemistry staining (IHC), ATP content, micRNA
The Perception of the Estomy-Individual Regarding of Its Situation

Study Overview
=================
Brief Summary
-----------------
The present work had as purpose to analyze estomy-individuals according to the feelings of their current situation.

Detailed Description
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The present work had as purpose to analyze estomy-individuals according to the feelings of their current situation. It is about a descriptive research of qualitative approach that took place in September, 2006. The population under study was composed by five estomy patients participants in a Grupo de Atenção dos Estomizados, which has multi-disciplinary character, at the Universidade da Região da Campanha (URCAMP) in the city of Bagé in South Brazil. The collection of data was given through not structuralized interviews and with the estomy-individuals, after the same ones read and signed the term of informed free ssent. The data form analyzed through the method of analysis of categories. Each one received a denomination with capital letters from the alphabet (A, B, D, and E) for their identification. The most significant categories in the answers from the ones being tested were manifestations and feelings of daptation, resignation and affective bond.The manifestation of anger and suffering shown by subjects D and E were only mentioned in this study, not being considered categories. The feeling shown by subjects A, B and C show an acceptance of their reality as rehabilitated from a surgical procedure, in the attempt of decreasing the psycho suffering caused by the mutilation and adaptation to the new status quo, fact which was observed for not appearing in the answers feeling such as revolt and guilty, which are mentioned in the review of literature as characteristics of subjects who suffered a surgical intervention. It is noticed that family support is a determinant fact to accept the new reality. The study contributed to know the subjectivity of the estomated, opening possibilities to improve the attention to health by the multi-professional staff. Descriptors: Perception; emotions; Adaptation; estomia

Official Title
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The Perception of the Estomy-Individual Regarding of Its Situation

Conditions
-----------------
Health Promotion, Health Behavior, Pharmaceutical Services, Psychology, Clinical

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Estomizados registered in the Single Health System users group's support of the University. Exclusion Criteria: Estomizados unable to come to the group of support for health reasons.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Perception, Emotions, Adaptation, Estomia