The Effect of Oxygen Therapy on Atelectasis

Study Overview
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Brief Summary
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In pregnancy, cephalal shift of the diaphragm caused by the enlarged uterus reduces the functional residual capacity and may increase the closure volume and predispose the pregnant woman to airway closure, leading to atelectasis. The development of atelectasis due to dermatomes retained in spinal anesthesia and intraoperative supine position may increase further. Oxygen therapy to be applied may also lead to absorption atelectasis by causing hyperoxia. The aim of our study is to evaluate the effect of oxygen support on the lungs in cesarean section operations under spinal anesthesia by lung ultrasound score and oxygen reserve index.

Official Title
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Evaluation of Oxygen Threapy by Lung Ultrasound and Oxygen Reserve Index in Patients Undergoing Cesarean Section Under Spinal Anesthesia

Conditions
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Atelectasis, Cesarean Section, Hypotension

Intervention / Treatment
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* Diagnostic Test: lung ultrasound score


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 18-50 years old ASA I-II Patients scheduled for elective cesarean section under spinal anesthesia Exclusion Criteria: alcohol or drug addiction, chronic obstructive pulmonary disease, cardiovascular disease, smokers anemia, liver or kidney disease, coagulation disorders allergic to anesthetic agents, sepsis or bacterial infection, body temperature is below 35°C and above 38°C Multiple pregnancy Preoperative hypoxemia SpO2<94% Diabetes mellitus Hypertension Placenta previa Premature rupture of membranes Intrauterine growth retardation Preeclampsia-eclampsia-fetal distress Polyhydramnios Morbid obesity BMI>45

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 47 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| group 0<br>control group | Diagnostic Test: lung ultrasound score<br>* determination of atelectasis by lung ultrasound score<br>|
| group 3<br>3 Lt/min Oxygen therapy via nasal cannula | Diagnostic Test: lung ultrasound score<br>* determination of atelectasis by lung ultrasound score<br>|
| group 6<br>6 Lt/min Oxygen therapy via Simple face mask | Diagnostic Test: lung ultrasound score<br>* determination of atelectasis by lung ultrasound score<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| atelectasis | measuring atelectasis due to oxygen therapy | during the surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| APGAR score | baby status after delivery | 1st and 5th min after delivery | 
| hypotension | maternal hypotension | during surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Atelectasis, lung ultrasound, oxygen reserve index, cesarean section