Detraining in People Living With HIV/AIDS

Study Overview
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Brief Summary
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The goal of this study was to evaluate the effect of detraining in the components of physical aptitude of people living with HIV/Aids (PVHA).

Detailed Description
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The study was experimental with a sample composed by an Experimental Group (EG) with 11 PVHA, under antiretroviral therapy and a Control Group (CG) with 10 individuals without the infection; all which were under medical release and insufficiently active. The body composition was evaluated through the DXA, as well as the cardiorespiratory aptitude through the ergometer and the strength of the upper and lower limbs through dynamometry. Both groups conducted interventions with concurrent training for 15 weeks and the interruption of exercise was evaluated after a period of 5 weeks.

Official Title
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Detraining in the Components of Physical Aptitude in People Living With HIV/ AIDS

Conditions
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Lipodystrophy Syndrome, HIV, Sarcopenia

Intervention / Treatment
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* Other: combined training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Group experience to have a diagnosis of at least 2 years living with HIV / AIDS being in clinical follow-up in the Specialized Attention Services in HIV / AIDS (SAE), using ART, TCD4 lymphocyte count equal to or greater than 500 copies / mm³, viral load Undetectable (≤ 50 copies / mm³) Group control without any diagnosis of HIV / AIDS or any other pathology. Both groups completed the exercise program with a minimum frequency of 75%. Exclusion Criteria: Both groups taking part in any physical exercise in time of detraining

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Intervention Model: Sequential Assignment
Interventional Model Description: This is a longitudinal study of the non-randomized experimental type, presenting a non-probabilistic sample for convenience and independent groups. The sample consisted of 21 individuals divided into 2 groups: Experimental Group (EG) and Control Group (CG). The EG was composed of 11 people living with HIV/AIDS and CG composed of 10 people with no infection
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: protocol with physical exercise<br>Both groups underwent a combined training intervention consisting of aerobic and resisted exercises in the same training session | Other: combined training<br>* Combined training consisting of aerobic and resisted training in the same training session for 15 weeks followed by 5 weeks of detraining<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Capacity cardiorespiratory | ml (cardiorespiratory aptitude through the ergometer) | 21 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| test force | kg (strength of the upper and lower limbs through dynamometry) | 21 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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HIV, Detraining, Physical aptitude