Three Different Oral Hygiene Regimes on Three Volatile Sulfur Compounds

Study Overview
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Brief Summary
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The purpose of the study is to evaluate the effect of various oral hygiene regimes on three volatile sulfur compounds.

Detailed Description
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Thirty male monk volunteers who matched with the including criteria were divided randomly into two groups. Both groups were practiced to brush their teeth with scrubbing method for one week. Then, each group were instructed to do different additional protocol regimen- group A have to do mouth washing and tooth brushing and group B have to practice tongue cleaning addition to tooth brushing for three weeks. At the fifth week, both groups were instructed to practice tooth brushing, mouth washing and tongue cleaning. Three different volatile sulfur compounds were measured by oral chroma. Tongue characteristics, oral examination were checked as the outcomes of this study.

Conditions
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Halitosis

Intervention / Treatment
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* Other: chlorine dioxide
* Other: small toothbrush for tongue cleaning


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Clinical diagnosis of oral malodor No systemic diseases and no severe dental diseases At least 20 functional teeth Exclusion Criteria: Risky oral habit (smoking and betel quid chewing) Current use of antibiotics or any drugs Current use of any kind of mouthwash

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 30 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: group A<br>Mouthwash (chlorine dioxide 12ml two times per day, for three weeks) | Other: chlorine dioxide<br>* First week, subjects were instructed to do regular tooth brushing. After that group A was requested to use chlorine dioxide mouthwash two time per days for three weeks in addition to tooth brushing and then, one week for combination of tooth brushing, tongue cleaning and mouth washing.<br>|
| Other: group B<br>Small toothbrush for tongue cleaning two times per day for three weeks | Other: small toothbrush for tongue cleaning<br>* First week, subjects were instructed to do regular tooth brushing. After that group B was requested to brush their tongue with small toothbrush two time per days for three weeks in addition to tooth brushing and then, one week for combination of tooth brushing, tongue cleaning and mouth washing.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Three different volatile sulfur compounds | Investigator measured three different volatile sulfur compounds: hydrogen sulfide, methyl mercaptan, dimethyl sulfide concentrations (ng/10ml) by using Oral chroma. | up to 5weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Oral Health examination | As oral examination, investigator examined present teeth, DMF-T (decayed, missing and filled teeth) | up to 5weeks | 
| Tongue coating characteristics | As tongue coating characteristics, investigator examined tongue coating score (by using winkle tongue coating index) at the baseline, one week later, four weeks later and five weeks later. | up to 5weeks | 
| Number of teeth with bleeding on probing |  | up to 5weeks | 
| Plaque index score |  | up to 5weeks |