Anatomical Location and Metastasis Pattern of Intrapulmonary Lymph Nodes in NSCLC (ECTOP-1010)

Study Overview
=================
Brief Summary
-----------------
This is a clinical trial from Eastern Cooperative Thoracic Oncology Project (ECTOP), numbered as ECTOP-1010. Anatomical Location and Metastasis Pattern of Intrapulmonary Lymph Nodes (Group 11-13) in Non-small Cell Lung Cancer: a Multi-center, Prospective observational Clinical Trial

Detailed Description
-----------------
Patients would be evaluated whether meet the criteria as clinical stage T1 non-small Cell Lung Cancer. Then, he/she would receive lobectomy. Finally, the detailed anatomical location of group 11-13 would be recorded immediately after surgery and their metastasis pattern would be explored in the follow-up period.

Official Title
-----------------
Anatomical Location and Metastasis Pattern of Intrapulmonary Lymph Nodes in Non-small Cell Lung Cancer: a Multi-center, Prospective Observational Clinical Trial

Conditions
-----------------
Carcinoma, Non-small Cell Lung Cancer

Intervention / Treatment
-----------------
* Procedure: pulmonary lobectomy


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Preoperative examination showed patients with clinical T1 peripheral non-small cell lung cancer (NSCLC); The lesion is located in a single lung segment or between two adjacent lung segments; Perform radical lobectomy; The preoperative examination did not reveal unresectable lymph nodes; Have not received any other tumor-related treatments (including chemotherapy, radiotherapy, targeted therapy, immunotherapy, etc.) before surgery; No malignant tumor history; No contraindications to surgery (ECOG score 0-1 points); Exclusion Criteria: Pathology revealed patients with non-T1 stage non-small cell lung cancer (NSCLC); Radical lobectomy is not performed; Acception of any anti-tumor treatment before surgery (excluding Chinese medicine treatment); Refused to enter the group or asked to leave the group.
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| RUL<br>patients who recieved the resection of right upper lobe (RUL) | Procedure: pulmonary lobectomy<br>* resection of lung lobe<br>|
| RML<br>patients who recieved the resection of right middle lobe () | Procedure: pulmonary lobectomy<br>* resection of lung lobe<br>|
| RLL<br>patients who recieved the resection of right lower lobe (RML) | Procedure: pulmonary lobectomy<br>* resection of lung lobe<br>|
| LUL<br>patients who recieved the resection of left upper lobe (LUL) | Procedure: pulmonary lobectomy<br>* resection of lung lobe<br>|
| LLL<br>patients who recieved the resection of left lower lobe (LLL) | Procedure: pulmonary lobectomy<br>* resection of lung lobe<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| metastasis rate of group 11-13 LN | metastasis rate of intrapulmonary lymph nodes (group 11-13 LN) in non-small cell lung cancer | one month after surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| detailed anatomical location | number of group 11-13 intrapulmonary lymph nodes in Non-small cell lung cancer and their detailed anatomical location | immediately after surgery | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Non-small Cell Lung Cancer, Intrapulmonary Lymph Nodes, Anatomical Location, Metastasis Pattern