3D Team Care for Cognitively Vulnerable Older Adults

Study Overview
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Brief Summary
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This study addresses how to achieve better outcomes for cognitively vulnerable community-dwelling older adults and their families. Cognitive vulnerability means living with dementia, depression, and/or a recent episode of delirium (the 3Ds). The investigators will test the effectiveness of a team care model focused on the 3Ds (Home Based Care Team) guided by nurse practitioners with expertise in geriatrics and geriatric psychiatry. Specific aims are to determine Home Based Care Team effects on hospitalization or emergency department use, and other outcomes including depression, disability, and quality of life.

Detailed Description
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This study addresses how to achieve better outcomes for cognitively vulnerable community-dwelling older adults and their families. Cognitive vulnerability means living with dementia, depression, and/or a recent episode of delirium (the 3Ds). Cognitive vulnerability in older adults is often overlooked by primary care and hospital-based providers, and represents a marker for overall vulnerability or frailty often missed when disease-specific approaches are emphasized in the care for older adults. Such patients often cannot adequately self-manage their comorbidities. Many studies of older adults and their families have demonstrated the great burden of living with cognitive vulnerability. The investigators will test the effectiveness of a team care model focused on the 3Ds (Home Based Care Team) guided by nurse practitioners with geriatrics expertise. Other team member disciplines will include pharmacy, social work, occupational and physical therapy, nutrition, and community health worker. Long-term objectives are to determine whether this care model can become a widely available approach for improving healthcare systems for older adults with cognitive vulnerability and their families, while improving outcomes of importance to these patients and families. A project Steering Committee, including cognitively vulnerable patients and family caregivers, will provide extensive input into many aspects of the research process.

Official Title
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3D Team Care for Cognitively Vulnerable Older Adults

Conditions
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Dementia, Depression, Delirium

Intervention / Treatment
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* Other: Home Based Care Team
* Other: Telephone Based Care Team


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Evidence of dementia, depression, and/or delirium, based on diagnostic codes found in medical claims data and based on screening at time of study screening. Living in the community, including assisted living facility, at time of randomization Plan to live in geographic area for 12 months Speak or understand English Willing to be randomly assigned to intervention or active comparator group Exclusion Criteria: Diagnosed schizophrenia or bipolar disorder Bedbound and non-communicative Life expectancy <12 months Already enrolled in active comparator program For individuals with dementia, family caregiver is unavailable or unwilling to enroll in study

Ages Eligible for Study
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Minimum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Home Based Care Team<br>Primarily in-home treatment provided by team led by nurse practitioner with geriatrics and geriatric psychiatry expertise. | Other: Home Based Care Team<br>* Clinical team will conduct comprehensive clinical assessments focused on cognitive impairment and depression, conduct comprehensive medication review and reconciliation, offer Problem Solving Therapy, and offer brief occupational therapy, physical therapy, nutrition, and social support services.<br>|
| Active Comparator: Telephone Based Care Team<br>Primarily telephone-based treatment provided by existing care management program offered by collaborating Medicare Advantage insurer. | Other: Telephone Based Care Team<br>* Telephone contact will be made by nurses. Depending on level of need, follow up telephone and, in some cases, in home visits will be made by nurse or social worker from care management program.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Proportion hospitalized or used emergency department without hospitalization | Evidence of hospitalization or visit to emergency department without hospital admission will be based on data from the Medicare Advantage insurer's medical claims data warehouse. | 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| GRID Hamilton Rating Scale for Depression (GRID-HAMD), 17-item version. | This measure yields a score for each individual reflecting both frequency and intensity of all depression-related symptoms included in the structured interview. This outcome will be used for study participants with depression but not dementia or recent episode of delirium at baseline. Individual scores will be aggregated into group mean scores to compare intervention and active comparator groups on this outcome. | 12 months | 
| Caregiver Assessment of Function and Upset (CAFU) | This measure yields a score for each individual reflecting level of assistance required to conduct 7 self-care activities of daily living (ADLs) and 8 instrumental ADLs. In a structured interview format, family members report these items for their relatives with dementia and/or a recent history of delirium. Individual scores will be aggregated into group mean scores to compare intervention and active comparator groups on this outcome. | 12 months | 
| Family caregiver perceived well-being | Self-reported well-being among family caregivers who enroll in the study | 12 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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older adults, family caregivers, Medicare Advantage beneficiaries