The Analgesic Effect of QLB II After Robotic Prostatectomy. (QLB II: Quadratus Lomborum Block II Type)

Study Overview
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Brief Summary
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The analgesic effects of Quadratus Lomborum Block II type after robotic-assisted laparoscopic radical prostatectomy, will be assessed.

Detailed Description
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Quadratus Lomborum Block II type will be performed before performing robotic-assisted laparoscopic radical prostatectomy. The post-operative analgesic effect will be assessed, by using Numeric Rate Scale for pain. The pain assessment will be evaluated during the first 24 hours from surgery. The opioids requirement and side effects will be also assessed.

Official Title
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The Analgesic Effect of Qudratus Lomborum Block II Type After Robotic-Assisted Laparoscopic Radical Prostatectomy.

Conditions
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Postoperative Pain

Intervention / Treatment
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* Other: Levobupivacaine in QLB II


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: American Society of Anesthesiologist status I-III Written informed consent Exclusion Criteria: Body mass Index > 35 kg/m2 Allergies to local anesthetics primaries or secondaries coagulopathies addiction to drugs severe kidney and liver diseases cognitive impairment

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Interventional Model Description: Simon's Two-Stage single arm study
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: QLB II<br>Quadratus Lomborum Blocck II type will be performed before robot-assisted laparoscopic radical prostatectomy | Other: Levobupivacaine in QLB II<br>* Quadratus Lomborum Block II type will be performed by injecting levobupivacaine 0.375% 20 ml between latissimus dorsi and quadratus lomborum muscle.<br>* Other names: Quadratus Lomborum Block II type;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Analgesia | Pain assessment by using Numeric Rate Scale for pain | The first 24 hours from surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Opioids | The opioids requirement (mg of equianalgesic morphine) will be assessed | The first 24 hours from surgery | 
| Postoperative Nausea and Vomiting | The postoperative nausea and vomiting will be assessed | The first 24 hours from surgery | 
| Bowel function | The recovery of bowel function will be assessed | The first 24 hours from surgery | 
| Length of stay | The length of stay after surgery will be assessed | Day after surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Pain, radical prostatectomy, QLB II type