linjc16/ctgov huggingface dataset:
Authentic Connections for Nurse Leaders

Study Overview
=================
Brief Summary
-----------------
The purpose of this pilot study is to test the feasibility and outcomes of a supportive group-based intervention, Authentic Connections, to be used for nurse leaders at Mayo Clinic, Rochester, in a collaboration involving faculty at Arizona State University (ASU) Department of Psychology, Dr. Sunyia Luthar.

Official Title
-----------------
Fostering Resilience Amongst Mothers Under Stress: Authentic Connections for Nurse Leaders

Conditions
-----------------
Stress

Intervention / Treatment
-----------------
* Behavioral: Authentic Connections
* Behavioral: Protected time


Participation Criteria
=================
Eligibility Criteria
-----------------
In an Nursing Education Specialist (NES) or Clinical Nurse Specialist (CNS) nurse leader role at Mayo Clinic Rochester Female gender A mother to at least one child or adult child

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Intervention group<br> | Behavioral: Authentic Connections<br>* Authentic Connections support groups for nurse leaders who are also mothers. Meetings occur once a week for one hour.<br>|
| Active Comparator: Control group<br> | Behavioral: Protected time<br>* Participants have one hour per week protected time scheduled on their calendar to do with what they choose.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Connor-Davidson Resilience Scale - 2 item | Two item scale, each of which has a 5-point range of responses, as follows: not true at all (0), rarely true (1), sometimes true (2), often true (3), and true nearly all of the time (4). The total score ranges from 0-8, with higher scores reflecting greater resilience. | Baseline | 
| Connor-Davidson Resilience Scale - 2 item | Two item scale, each of which has a 5-point range of responses, as follows: not true at all (0), rarely true (1), sometimes true (2), often true (3), and true nearly all of the time (4). The total score ranges from 0-8, with higher scores reflecting greater resilience. | 12 weeks | 
| Connor-Davidson Resilience Scale - 2 item | Two item scale, each of which has a 5-point range of responses, as follows: not true at all (0), rarely true (1), sometimes true (2), often true (3), and true nearly all of the time (4). The total score ranges from 0-8, with higher scores reflecting greater resilience. | 24 weeks | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Nurse leader, Resilience, Parenting, Stress, Depression
A Standardized Bundle Protocol to Optimize Outcomes With Patients Undergoing Gynecological Surgery

Study Overview
=================
Brief Summary
-----------------
Difference in outcome measures with the addition of post-operative evidence based bundle pre-operative education compared to standard pre-operative education given to patients prior to hysterectomy.

Detailed Description
-----------------
The purpose of this project is to evaluate whether there is a difference in outcome measures (length of stay, occurrence of readmission, and patient satisfaction) with the addition of a post-operative evidence-based bundle/standard pre-operative education compared to standard pre-operative education alone that is given to patients prior to a hysterectomy (open, vaginal, or laparoscopic).

Official Title
-----------------
A Standardized Bundle Protocol to Optimize Outcomes With Patients Undergoing Gynecological Surgery

Conditions
-----------------
Hysterectomy

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients who are admitted for all hysterectomies from October 1, 2017 through December 31, 2017, who speak English, and who are discharged home.
Sexes Eligible for Study
-----------------
Female

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Post-op evidence based bundle w/ Pre-op education<br>25 patients undergoing hysterectomy from October 1, 2017 to December 31, 2017 will receive the post-operative evidence based bundle/standard pre-operative education. | |
| Standard pre-operative education alone<br>25 patients undergoing hysterectomy from October 1, 2017 to December 31, 2017 will receive the standard pre-operative education alone. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Length of Stay | Number of days spent in the hospital from the first post-operative day to the day of discharge | 0 to 30 days | 
| Occurrence of Re-Admission | Re-admission within 30 days will be measured through the EMR | 0 to 30 days | 
| Patient Satisfaction | Patient Satisfaction Survey that consists of 7 questions utilizing a likert scale from excellent to poor | 0 to 30 days |
Self-management Behaviors and Resilience Among Chronic Obstructive Pulmonary Disease Patients

Study Overview
=================
Brief Summary
-----------------
This study conducted an assessment of the influencing factors and correlations that affect self-management behaviors and resilience in the COPD population.

Detailed Description
-----------------
A total of 100 participants with COPD from a medical center in Northern Taiwan were recruited from February 2020 to January 2021 in this cross-sectional study. Each subject completed self-reported questionnaires through face-to-face interviews, including 20-item COPD Self-Management Scale (CSMS-20) and a 25-item Connor-Davidson Resilience Scale (CD-RISC-25). A multiple linear regression model was used to examine the relationship between the levels of self-management behavior and resilience, controlling for sociodemographic and clinical factors.

Official Title
-----------------
The Relations of Resilience to Self-management Behaviors Among Patients With Chronic Obstructive Pulmonary Disease

Conditions
-----------------
Chronic Obstructive Pulmonary Disease, Self-management Behavior, Resilience

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: The recruited participants have been diagnosed with COPD for at least a month by thoracic physicians based on the guidelines of the Global Initiative for Chronic Obstructive Lung Disease (GOLD). Exclusion Criteria: Participants who were diagnosed with serious mental disorders, cancer, terminal illness, or end-stage diseases were excluded from this study.
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Levels of COPD self-management behavior | Each subject completed the self-reported 20-item COPD Self-Management Scale (CSMS-20) questionnaire through face-to-face interviews. The range of scores is from 20 to 100, with a higher score indicating better self-management behaviors. | 2020-02-01 to 2021-01-30 | 
| Levels of COPD psychological resilience | Each subject completed the 25-item Connor-Davidson Resilience Scale (CD-RISC-25) questionnaire through face-to-face interviews. The range of scores is from 0 to 100, with a higher score indicating better psychological resilience. | 2020-02-01 to 2021-01-30 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
chronic obstructive pulmonary disease, self-management behavior, resilience
Comparison of Post-operative Pain at Umbilical Wound After Laparoscopic Cholecystectomy With Transumbilical Versus Infraumbilical Incision

Study Overview
=================
Brief Summary
-----------------
This study compare outcomes (i.e. pain, wound infection, and patient satisfaction) between infra-umbilical vs. trans-umbilical incision after Laparoscopic cholecystectomy

Detailed Description
-----------------
Infra-umbilical wound have been used for a while with aim at improving cosmoses of the incision. Formerly, standard incision for laparoscopic cholecystectomy was infra-umbilical wound. However, no study directly compare these types of incisions in term of postoperative pain, wound infection, and patient satisfaction.

Conditions
-----------------
Pain, Postoperative, Gallstone

Intervention / Treatment
-----------------
* Procedure: transumbilical incision
* Procedure: Infra umbilical incision


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: elective laparoscopic cholecystectomy willing to participate Exclusion Criteria: pregnancy immunocompromised host on continuous ambulatory peritoneal dialysis morbid obesity (Body mass index > 35 kg/m2) End-stage renal disease with hemodialysis dependent ascites uncontrolled coagulopathy

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: transumbilical wound<br>transumbilical incision | Procedure: transumbilical incision<br>* incision within umbilicus<br>|
| Active Comparator: infra umbilical wound<br>infra umbilical incision | Procedure: Infra umbilical incision<br>* incision about 1 cm below umbilicus<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative pain | visual analog scale (0-10) | 7 days postoperatively | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| wound infection | yes or no according to Center for Disease Control and Prevention (CDC) criteria | at 1 week and 1 month postoperatively | 
| patient satisfaction | Visual analog scale (0-10) | 1 week and 3 months postoperatively |
Acute Kidney Injury as a Risk Factor for Myocardial Injury and Ventricular Dysfunction

Study Overview
=================
Brief Summary
-----------------
Acute kidney injury (AKI) is classically described as an abrupt or rapidly reversible reduction in the excretion of nitrogenous waste products, including urea, nitrogen and creatinine. Acute kidney injury definition emphasizes on the filtration function of the kidney, a measure that is unique and easily and routinely measured . Acute kidney injury is associated with significantly increased resource utilization and health care costs. Major adverse cardiac events (MACE) after non cardiac surgery are a leading cause of morbidity and mortality. The reported incidence of postoperative myocardial infarction (POMI) among patients undergoing non cardiac surgery is between 3% and 6%.

Official Title
-----------------
Assessment of Acute Kidney Injury as a Risk Factor for Myocardial Injury and Ventricular Systolic Dysfunction After Non-Cardiac Surgery in Critical Patients

Conditions
-----------------
Acute Kidney Injury, Ventricular Dysfunction, Myocardium; Injury

Intervention / Treatment
-----------------
* Diagnostic Test: kidney assessment


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients with normal kidney functions and free normal heart functions, were enrolled to this study Exclusion Criteria: patients with chronic kidney disease, cardiac disease, who with minor operations, or emergency, were excluded from the study.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: kidney assessment|Urea, BUN, and Creatinine BLOOD LEVELS|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| development myocardial injury | New echocardiographic findings suggestive of ischemia (new regional wall motion abnormalities) or cardiac troponin T >.0.32 ng/ml | through study completion, an average of 15 days |
A Long Term Study of GK530G in Subjects With Acne Vulgaris

Study Overview
=================
Brief Summary
-----------------
This open label study is to determine the safety profile of GK530G in a long-term treatment (up to 12 months) in subjects with acne vulgaris and to evaluate the efficacy of GK530G in a long-term treatment.

Official Title
-----------------
A Long Term Study of GK530G in Subjects With Acne Vulgaris

Conditions
-----------------
Acne Vulgaris

Intervention / Treatment
-----------------
* Drug: GK530G


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Men and women at the age of 12 or older at the Screening visit. Those with clinical diagnosis of acne vulgaris with more than 20 non-inflammatory lesions (open and closed comedones) and 12 to 100 (inclusive) inflammatory lesions (papules, pustules and nodules) on the face (forehead, both cheeks, nose and chin). Exclusion Criteria: Those with more than two nodular acne lesions or any cyst. Those with the diagnosis of any acne conglobata, any acne fulminans, any chloracne, or any drug induced acne. Those who have clinically significant abnormal findings or conditions on skin other than acne such as atopic dermatitis, perioral dermatitis, or rosacea that potentially interfere with study assessments according to Investigator's judgment

Ages Eligible for Study
-----------------
Minimum Age: 12 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: GK530G<br>GK530G is the fixed-dose combination gel of Adapalene and Benzoyl Peroxide, BPO | Drug: GK530G<br> <br> * Other names: Fixed-dose combination gel of Adapalene and Benzoyl Peroxide;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Local Tolerability (Erythema) | Highest severity of Local tolerability scores worth than base line | 12 monhths | 
| Local Tolerability (Scaling) | Highest severity of Local tolerability scores worth than base line | 12 months | 
| Local Tolerability (Dryness) | Highest Severity of Local Tolerability Scores Worse Than Baseline | 12 months | 
| Local Tolerability (Pruritus) | Highest Severity of Local Tolerability Scores Worse Than Baseline | 12 months | 
| Local Tolerability (Stinging/Burning) | Highest Severity of Local Tolerability Scores Worse Than Baseline | 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Percent Changes From Baseline in Total Lesion Counts |  | Baseline, Weeks 1, 2, 4, and Months 2, 3, 6, 9, 12 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Acne Vulgaris
Duration of Doxycycline Treatment in EM Patients

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to compare the efficacy of 7-day versus 14-day doxycycline treatment in patients with erythema migrans.

Official Title
-----------------
Duration of Doxycycline Treatment in Patients With Erythema Migrans (EM). A Randomized Clinical Trial.

Conditions
-----------------
Erythema Chronicum Migrans

Intervention / Treatment
-----------------
* Drug: Doxycycline 100 MG Oral Tablet bid, 7 days
* Drug: Doxycycline 100 MG Oral Tablet bid, 14 days
* Drug: Controls without a history of lyme disease.


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: solitary erythema migrans Exclusion Criteria: pregnancy or lactation immunocompromised serious adverse event to doxycycline taking antibiotic with antiborrelial activity within 10 days multiple erythema migrans or extracutaneous manifestations of lyme borreliosis

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: EM-7 days doxycycline<br> | Drug: Doxycycline 100 MG Oral Tablet bid, 7 days<br>* Patients will receive doxycycline for 7 days.<br>|
| Active Comparator: EM-14 days doxycycline<br> | Drug: Doxycycline 100 MG Oral Tablet bid, 14 days<br>* Patients will receive doxycycline for 14 days.<br>|
| Placebo Comparator: Controls<br> | Drug: Controls without a history of lyme disease.<br>* No intervention.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Treatment outcome in patients treated for erythema migrans with doxycycline for 7 or 14 days | Objective sequelae and post-treatment subjective new or increased symptoms (NOIS) in patients treated for erythema migrans with doxycycline for 7 or 14 days. | At 12 months after enrollment. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Comparison of nonspecific symptoms in patients with erythema migrans and control subjects | Number of patients after treatment with doxycycline for 7 or 14 days for erythema migrans and number of control subjects (without a history o Lyme borreliosis) with nonspecific symptoms. | At 12 months after enrollment. |
A Population-based Study of Macular Choroidal Neovascularization in a Chinese Population

Study Overview
=================
Brief Summary
-----------------
To investigate pathomorphological and functional variations of choroidal neovascularization (CNV) in age-related macular degeneration (AMD) in a Chinese population using optical coherence tomography (OCT) to find which kinds of Fundus characteristics indicated exudative AMD.

Detailed Description
-----------------
This population-based study enrolled 59 patients (>45 years old; 70 eyes) with early and intermediate-stage AMD from Youyi Street, Baoshan District, Shanghai, China. Comprehensive standardized ophthalmic examinations included visual acuity, anterior segment analysis by slit lamp, dilated fundus evaluation by direct ophthalmoscopy, 90D handheld lens, fundus photography, fluorescein angiography (FFA), and fast optic disk scans using OCT. The macular CNV characteristic profiles in early and intermediate-stage AMD were determined by OCT. Data were obtained at first visit and 6 to 24 months follow-up, and FFA and OCT outcomes of early and intermediate-stage AMD patients were analyzed.

Official Title
-----------------
A Population-based Study of Macular Choroidal Neovascularization Using Optical Coherence Tomography in a Chinese Population

Conditions
-----------------
Geographic Atrophy, Wet Macular Degeneration, Retinal Drusen

Intervention / Treatment
-----------------
* Other: Follow-up observation


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: adults citizens aged above 45 years Exclusion Criteria: lost samples

Ages Eligible for Study
-----------------
Minimum Age: 45 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| early and intermediate-stage AMD<br>Follow-up observation was implemented in whose fundus examination show lesions in the early and intermediate-stage AMD | Other: Follow-up observation<br>* a epidemiologic survey of ocular diseases in an adult population (>45 years old) in Youyi Street, Baoshan District, Shanghai, China, conducted to determine the prevalence of AMD in the region. To this end, we utilized routine ocular examinations<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| change of the early and intermediate-stage AMD | Drusen with unclear boundaries and obvious pigment proliferation, with hypofluorescence around drusens seen on FFA and a slight small arch field located in the retinal pigment epithelium (RPE)/choriocapillary layer (CCL) on OCT indicated exudative AMD. | May 2004-September 2008 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
macular degeneration; choroidal neovascularization