Study of the Immediate and Long-term Outcomes of the Disease in Patients With Left Ventricular Aneurysm Complicated and Uncomplicated by Thrombosis After Transmural Myocardial Infarction, According to the Hospital Registry: SIBYL

Study Overview
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Brief Summary
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A prospective non-interventional study aimed to evaluate the immediate and long-term outcomes in patients with left ventricular aneurysm after transmural myocardial infarction. A registry of patients with transmural myocardial infarction admitted to the Emergency Department of Cardiology will be created. The registry will include all consecutive hospitalized patients from from January 1, 2021 to December 31, 2021 who meet the inclusion criteria Based on this registry, patients will be divided into groups : patients with left ventricular aneurysm and patients without aneurysm, patients with left ventricular thrombosis and patients without thrombosis. Patients will be contacted in 3 and 12 months. Surviving patients will be invited to appointment for an ECG, echocardiography and survey. The cardiovascular events during this period will be recorded. The factors determining the prognosis of patients and their concomitant diseases, immediate and long-term prognoses, therapeutic measures and drug therapy at the hospital and outpatient stages, and patients ' adherence to therapy will be analyzed.

Official Title
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Study of the Immediate and Long-term Outcomes of the Disease in Patients With Left Ventricular Aneurysm Complicated and Uncomplicated by Thrombosis After Transmural Myocardial Infarction, According to the Hospital Registry

Conditions
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Myocardial Infarction

Intervention / Treatment
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* Other: Not Provided


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Men and women who had acute transmural myocardial infarction and who were hospitalized to the Emergency Cardiology Department of the N. V. Sklifosovsky Research Institute of Emergency Medicine from January 1, 2021 to December 31, 2021 Patients from 18 to 85 years of age Patients who live in Moscow and Moscow region Patients who signed the consent to participate in the study and processing of personal data. Exclusion Criteria: Patients who refused to come for a second appointment or answer the questionnaire questions Patients who had repeated myocardial infarction Non-compliance with inclusion criteria

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| study group№ 1<br>patients who have left ventricular aneurysm without thrombosis | Other: Not Provided<br>* Not Provided<br>|
| study group№ 2<br>patients who have left ventricular aneurysm with thrombosis | Other: Not Provided<br>* Not Provided<br>|
| control group<br>patients who have not left ventricular aneurysm | Other: Not Provided<br>* Not Provided<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| All cause mortality | Patients with a fatal outcome will be identified. We will contact the relatives of the deceased patients to clarify the date of death. | 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cumulative number cardiovascular events | Cardiovascular event is defined on of the following repeated myocardial infarctions, brain strokes, PCI, CABG, pulmonary embolism. | 12 months | 
| Assessment of adherence | To assess adherence to the recommended therapy at enrollment and during the first and second visits, the original questionnaire The Scale of Adherence of the National Society for Evidence-based Pharmacotherapy will be used. The commitment scale has two modifications to assess potential and initial actual commitment. The questionnaire can be used both to assess overall adherence to drug therapy and to diagnose adherence to a specific drug. The maximum number of points on the scale is 4 points. The minimum number of points on the scale is 0 points. 4 points means complete non-adherence. 0 points means full commitment. | baseline, 3 months, 12 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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left ventricular aneurysm, transmural myocardial infarction