Efficacy of Topical Capsaicin on Chronic Neck Pain

Study Overview
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Brief Summary
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The purpose of this study is to determine whether topical capsaicin patch can effectively reduce chronic neck pain.

Detailed Description
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Design: This is a double-blind, randomized, controlled study. Participants: Sixty participants with chronic neck pain are recruited and randomly assigned to two groups. Intervention: Over an four-week period, the treatment group (n=30) uses capsaicin patch (100 mcg/3cc) at the tender point of neck for 12 hours a day; the control group (n=30) receives Hydrogel patch instead of capsaicin patch.

Official Title
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Efficacy of Topical Capsaicin on Chronic Neck Pain ; Double-blinded Randomized Trial

Conditions
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Chronic Neck Pain

Intervention / Treatment
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* Drug: Capsaicin patch


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Korean participants with Chronic neck pain are enrolled in our study Exclusion Criteria: Participants with coagulation deficiencies, infections, hypertension, diabetes, heart disease, renal disease, liver disease, cancer, myelopathy, hypersensitivity of drugs, other skeletomuscular disease, allergic response to capsaicin, pregnancy and nursing are excluded

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: capsaicin patch<br> | Drug: Capsaicin patch<br>* Over an four-week period, the treatment group (n=30) uses capsaicin patch (100 mcg/3cc) at the tender point of neck for 12 hours a day; the control group (n=30) receives Hydrogel patch instead of capsaicin patch.<br>* Other names: Hydrogel Patch;|
| Placebo Comparator: Hydrogel patch<br> | Drug: Capsaicin patch<br>* Over an four-week period, the treatment group (n=30) uses capsaicin patch (100 mcg/3cc) at the tender point of neck for 12 hours a day; the control group (n=30) receives Hydrogel patch instead of capsaicin patch.<br>* Other names: Hydrogel Patch;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain Scores on the Visual Analogue Scale(VAS) |  | 4 week | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Neck disability index | Neck disability index : questionnaire for measuring how much neck pain affects ability of daily activities | 4 week | 
| Beck depression inventory | Beck depression inventory : for assessing depression | 4 week | 
| SF-36 | questionnaire for measuring health-related quality of life | 4 week | 
| EQ-5D(EuroQol-5 dimension) | questionnaire for measuring health-related quality of life | 4 week | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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neck pain, capsaicin, dermal patch