Knee Kinematics for Subjects With Zimmer-Biomet Posterior Cruciate Retaining or Posterior Stabilizing Total Knee Arthroplasty

Study Overview
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Brief Summary
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25 subjects implanted with a Zimmer-Biomet Posterior Cruciate Retaining (PCR) total knee arthroplasty (TKA) and 25 subjects implanted with a Zimmer-Biomet Posterior Stabilizing (PS) TKA will be asked to perform stepping up and deep knee bend activities while under fluoroscopic surveillance (x-ray video). The movements between the two different types of TKAs will be compared.

Official Title
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In Vivo Determination of Knee Kinematics for Subjects Having a Zimmer-Biomet Persona PCR or PS TKA

Conditions
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Arthroplasty, Replacement, Knee, Osteoarthritis, Knee

Intervention / Treatment
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* Device: Zimmer-Biomet Posterior Cruciate Retaining total knee arthroplasty
* Device: Zimmer-Biomet Posterior Stabilizing total knee arthroplasty


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Subjects will have a Zimmer Persona PCR or PS TKA. Subjects must be at least six months post-operative. Subjects will have KSS greater than 75. Participants must be able to perform the required activities - stepping up and a deep knee bend. Subjects must be willing to sign the Informed Consent (IC) / HIPAA form to participate in the study. Bilateral subjects may be included in the subject population Exclusion Criteria: Pregnant, potentially pregnant or lactating females. To satisfy radiation protocol, each female subject will be asked if she is pregnant, or possibly could be pregnant. A pregnant person will not be allowed to participate in the study. To ensure this, a pregnancy test will be administered to any female participants of child bearing age who have not had a hysterectomy. Subjects without the required type of knee implant. Subjects who are unable to perform stepping up and deep knee bend. Subjects who are unwilling to sign Informed Consent/HIPAA documents. Subjects who do not speak English and/or French

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Subjects implanted with PCR TKA<br>Subjects who have been implanted with a Zimmer-Biomet Posterior Cruciate Retaining total knee arthroplasty | Device: Zimmer-Biomet Posterior Cruciate Retaining total knee arthroplasty<br>* Zimmer-Biomet Posterior Cruciate Retaining total knee arthroplasty<br>|
| Subjects implanted with PS TKA<br>Subjects who have been implanted with a Zimmer-Biomet Posterior Stabilizing total knee arthroplasty | Device: Zimmer-Biomet Posterior Stabilizing total knee arthroplasty<br>* Zimmer-Biomet Posterior Stabilizing total knee arthroplasty<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Lateral Condyle Kinematic Translations - Step up | Lateral Condyle Kinematics Translations during stepping up activity. Data represents the motion of a specific part of the femur bone (in this case lateral femoral condyle) during the specified activity (in this case a step up). The kinematics (motion) is measured from the beginning of the activity to the end of the activity. Positive represents anterior motion of the femur, and negative represents posterior rollback of the femur. Data is only collected at a single time point and therefore refers to the motion of the femur bone during a specific activity at a single point in time. | Baseline | 
| Lateral Condyle Kinematics Translations - Deep Knee Bend | Lateral Condyle Kinematics Translations during deep knee bend activity. Data represents the motion of a specific part of the femur bone (in this case lateral femoral condyle) during the specified activity (in this case a deep knee bend). The kinematics (motion) is measured from the beginning of the activity to the end of the activity. Positive represents anterior motion of the femur, and negative represents posterior rollback of the femur. Data is only collected at a single time point and therefore refers to the motion of the femur bone during a specific activity at a single point in time. | Baseline | 
| Medial Condyle Kinematics Translations - Step Up | Medial Condyle Kinematics Translations during stepping up activity. Data represents the motion of a specific part of the femur bone (in this case medial femoral condyle) during the specified activity (in this case a step up). The kinematics (motion) is measured from the beginning of the activity to the end of the activity. Positive represents anterior motion of the femur, and negative represents posterior rollback of the femur. Data is only collected at a single time point and therefore refers to the motion of the femur bone during a specific activity at a single point in time. | Baseline | 
| Medial Condyle Kinematics Translations - Deep Knee Bend | Medial Condyle Kinematics Translations during deep knee bend activity. Medial Condyle Kinematics Translations during stepping up activity. Data represents the motion of a specific part of the femur bone (in this case medial femoral condyle) during the specified activity (in this case a deep knee bend). The kinematics (motion) is measured from the beginning of the activity to the end of the activity. Positive represents anterior motion of the femur, and negative represents posterior rollback of the femur. Data is only collected at a single time point and therefore refers to the motion of the femur bone during a specific activity at a single point in time. | Baseline |