Observational Study of Correlation Between Recurrent Basal Cell Carcinoma and Localisation

Study Overview
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Brief Summary
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.During one year all the resected basal cell carcinomas (BCC) analyzed in Montpellier University Hospital Anatomopathology unit were included in this study. Localisation and histological characteristics were collected. All the recurrences of BCC were searched from the medical records (or histopathology request form). From 804 BCC, 48 were recurrent BCC with or without complete first resection. Patients with recurrent BCC were contacted to obtain agreement and more informations about the first resection and some clinical informations like sun exposure and phototype. The statistical analysis focused on the localisation of recurrent BCC (with a complete first resection) compared to localisations of primary BCC in this population. The goal was to identified localisations with an increased risk of recurrences.

Official Title
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Observational Study of Basal Cell Carcinoma Operated at Montpellier University Hospital and Millau Hospital From February 2020 to February 2021 - Study of Correlation Between Localisation and Recurrence, and Other Criterias

Conditions
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Basal Cell Carcinoma

Participation Criteria
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Eligibility Criteria
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Cohort : Inclusion criteria: - Patients with resected BCC Exclusion criteria: Biopsies of BCC, revised surgery of incomplete resection. Cases : Inclusion criteria: -Recurrent BCC with complete first resection Exclusion criteria: - Recurrent BCC with incomplete first resection, Patients with Gorlin syndrome (a genetic disease that increase risk of BCC)

Ages Eligible for Study
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Minimum Age: 16 Years
Maximum Age: 99 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| recurrent BCC<br>recurrent BCC | |
| resected BCC<br>resected BCC | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| - Determined For each localisation the number of primary and recurrent BCC and analysis of localisation with higher risk of BCC | - Determined For each localisation the number of primary and recurrent BCC and analysis of localisation with higher risk of BCC | 1 day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Analysis of correlation between localisation and histology characteristics | Analysis of correlation between localisation and histology characteristics | 1 day | 
| Analysis of correlation between histological type and recurrence risk | Analysis of correlation between histological type and recurrence risk | 1 day | 
| Analysis if there is a difference between first resection histological type and the recurrent histological type | Analysis if there is a difference between first resection histological type and the recurrent histological type | 1 day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Resection of BCC (Basal Cell Carcinoma), Recurrence of BCC (Basal Cell Carcinoma), Localisation