TAP Block and Subacute Pain in Inguinal Herniography

Study Overview
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Brief Summary
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Inguinal hernia repair with mesh has a high incidence of postoperative chronic pain. Transversus abdominis plane block is a current intervention to support postoperative analgesia, however it is recently in research area how to be applied in different surgical areas to be more effective than intravenous opioids. Subcostal transversus abdominis plane block is not advised but has not been studied to be effective for postoperative analgesia in inguinal herniography patients. This study aims to research the effect of subcostal transversus abdominis plane block in subacute postoperative pain after inguinal hernia repair

Detailed Description
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Patients were divided into two groups, one is control and the second is subcostal transversus abdominis plane block (STAP) group. After standard general anesthesia application, control group ( Group I) had 1 gram of paracetamol and 100 mg of contramal just after starting surgical closure. Group II (STAP) had 1 gram of paracetamol and 100 mg of contramal, after surgical closure transversus abdominis plane block in subcostal area was applied to the patient.

Official Title
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Evaluation of the Effects of Subcostal Transversus Abdominis Plane Block on Subacute Pain Development Following Inguinal Herniography: a Randomized Clinical Study

Conditions
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Postoperative Pain

Intervention / Treatment
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* Procedure: transversus abdominis plane block
* Drug: Tramadol and paracetamol


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: ASA I-III who were to undergo elective unilateral inguinal herniography with mesh under general anesthesia. Exclusion Criteria: patients who have allergy to local anesthetics

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Tramadol and paracetamol<br>subjects were administered intravenous analgesia (control group) Tramadol 100 mg and paracetamol 1000 mg at the end of the surgery | Drug: Tramadol and paracetamol<br>* Tramadol 100 mg and paracetamol 1000 mg are applied to the patients at the end of the surgery<br>* Other names: parol infusion solution;|
| Active Comparator: transversus abdominis plane block<br>patients that applied transversus abdominis plane block at the end of the surgery after given intravenous analgesia | Procedure: transversus abdominis plane block<br>* A peripheric block needle is inserted entering the facia between musculus rectus abdominis and musculus transversus abdominis with ultrasonography and local anesthetics are injected in the facia.<br>* Other names: stimuplex A;Drug: Tramadol and paracetamol<br>* Tramadol 100 mg and paracetamol 1000 mg are applied to the patients at the end of the surgery<br>* Other names: parol infusion solution;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| verbal numeric scale | patients were questioned for pain graduation to give a point from 0 to 10 according to the intensity of the pain. 0 equals to no pain, 10 equals to the strongest pain | 1 month after the operation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| verbal numeric scale | according to the intensity of the pain. 0 equals to no pain, 10 equals to the strongest pain | 15 minutes, 1-6-12-24 hours and 15 days after operation | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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TAP block, subacute pain, inguinal herniography