Detection of Electrocardiographic Brugada Patterns Using High Precordial Leads

Study Overview
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Brief Summary
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Detection of prevalence of Brugada patterns in our locality in asymptomatic patients , by standard 12 lead ECG level and high precordial ECG level, measuring how much the high precordial leads is more sensitive in Brugada patterns detection than standard level 12 lead ECG in our upper Egyptian population.

Detailed Description
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Detection of prevalence of Brugada patterns in our locality in asymptomatic patients , by standard 12 lead ECG level and high precordial ECG level, measuring how much the high precordial leads is more sensitive in Brugada patterns detection than standard level 12 lead ECG in our upper Egyptian population. The study will include patients fulfilling our criteria presenting to cardiology outpatient clinic and emergency room of Assiut University hospitals.

Official Title
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Detection of Electrocardiographic Brugada Patterns Using High Precordial Leads Positioning Among Asymptomatic Upper Egyptian Population

Conditions
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Brugada ECG Patterns

Intervention / Treatment
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* Diagnostic Test: ECG(electrocardigraph)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients with IHD,HTN,DM with no organic heart disease by ECHO. healthy persons with normal structure heart by ECHO. Exclusion Criteria: Acute coronary syndrome. cardiomyopathy. severe valvular heart disease. HTN heart disease with LVH. Malignancy.

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: ECG(electrocardigraph)|Detection of electrocardiographic Brugada patterns using high precordial leads positioning as placing the precordial leads in the second intercostal space has been proposed to add sensitivity to the ECG diagnosis of Brugada syndrome.|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Detection of electrocardiographic Brugada patterns using high precordial leads positioning among asymptomatic upper Egyptian population | Detection of prevalence of Brugada patterns in our locality in asymptomatic patients , by standard 12 lead ECG level and high precordial ECG level, measuring how much the high precordial leads is more sensitive in Brugada patterns detection than standard level 12 lead ECG in our upper Egyptian population. | up to 4 hours for each case to make sure of meeting eligibility criteria | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Follow up of positive cases | The positive cases will be educated regarding their condition, asked about their history of syncope and family history of sudden cardiac death and will be educated about avoiding and rapid management of fever and electrolyte disturbances and educated about the list of drugs to be avoided. The positive cases will be followed up for 6 months both clinically and by Holter at 1st, and 6th month for detection of subclinical ventricular arrhythmias. | six months after diagnosis of Brugada pattern for each case |