Speech Therapy in the Management of Chronic Cough

Study Overview
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Brief Summary
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Speech and language intervention (speech therapy) is one of the few methods which seem to be useful in management of persistent chronic cough. This method has not been available for patients with cough in Poland so far.The aim of the study is to implement speech therapy to the management plan of patients with difficult-to-treat chronic cough and to analyze its efficacy in this particular group. Patients with difficult-to treat chronic cough will be offered speech and language intervention as an added therapy. The effectiveness of speech therapy will be measured by changes in cough severity, its influence on quality of life and cough challenge test before and after speech therapy measured in every patient.

Detailed Description
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The efficacy of management of chronic cough in adults is limited. Speech and language intervention (speech therapy) is one of the few methods which seem to be useful in management of persistent chronic cough. This method has not been available for patients with cough in Poland so far. The aim of the study is to implement speech therapy to the management plan of patients with difficult-to-treat chronic cough and to analyze its efficacy in this particular group. Patients, who are diagnosed and unsuccessfully managed because of difficult-to treat chronic cough, will be offered speech and language intervention as an added therapy. It is based on the technique described by Vertigan et al.The entire therapy will consist of eight sessions once a week. Cough severity, its influence on quality of life and cough challenge test with capsaicin will be assessed by Visual Analogue Scale, Leicester Cough Questionnaire and cough challenge test with capsaicin will be performed before and after speech therapy in every patient to analyze its effectiveness

Official Title
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Speech Therapy in the Management of Difficult-to-treat Chronic Cough

Conditions
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Cough, Speech Therapy

Intervention / Treatment
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* Behavioral: Speech and language intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: age between 18 and 80 years, chronic cough lasting more than six months earlier thorough diagnosing of cough reason unsuccessful cough management despite at least 3 months of earlier treatment no symptoms of any airway infection during last 4 weeks. Exclusion Criteria: lack of opportunity to participate in speech therapy sessions cough lasting less than 6 months active cigarette smoking taking ACE inhibitors symptoms of airway infection (other than cough).

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Interventional Model Description: prospective, single arm, single center study
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Speech and language intervention<br> | Behavioral: Speech and language intervention<br>* Speech therapy includes education about cough and vocal hygiene, teaching strategies to reduce cough, breathing and vocal exercises. The whole therapy consists of eight sessions once a week.<br>* Other names: Voice therapy;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cough severity | measured by Visual Analogue Scale (VAS), range 0-100 mm, the more severe cough , the higher value in VAS score | 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cough related quality of life | measured by Leicester Cough Questionnaire (LCQ)- health related Quality of Life Questionnaire dedicaated for patients, who cough; rangeof total LCQ is 3 to 21 points; higher values represent less intense cough | 3 months | 
| Sensitivity of cough reflex | measured by cough challenge test with capsaicin | 3 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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chronic cough, speech and language intervention, difficult-to-treat cough