Evaluation of the Sleep-relieving Effect of Banana Peel Extract

Study Overview
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Brief Summary
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Banana peel has the potential to improve sleep quality. The purpose of this research is to test the effect of banana peel on improving sleep quality.

Detailed Description
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Insomnia is one of the most frequently complained sleep problems in sleep disorders, and in recent years has been regarded by the medical community as a disease that seriously affects people's lives and quality of life. The problem of perishable and perishable causes a great burden on the environment. However, banana peels actually contain many functional ingredients, such as dietary fiber, minerals, alkaloids, flavonoids, phenols, saponins, tannins and dopamine, etc. Banana peel contains more total phenols and total flavonoids than banana pulp. Studies have pointed out that banana peel extraction can inhibit the growth of fungi and bacteria. In addition, it also has antioxidant, anti-depressant, and diuretic functions. Banana peel can also improve the performance of tryptophan metabolism-related genes

Official Title
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Explore Whether Banana Peel Extract Can Improve Sleep

Conditions
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Impaired Attention

Intervention / Treatment
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* Dietary Supplement: Placebo
* Dietary Supplement: Banana peel extract


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 1.20 to 65-year-old males or non-pregnant females who are willing to sign the subject's consent. 2.Pittsburgh Sleep Quality Index (PSQI) score> 5 Exclusion Criteria: Taking sleeping pills and melatonin People suffering from mental illness Pregnant or breastfeeding women People who are known to be allergic to bananas Have heart-related diseases People with symptoms of sleep cessation

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Placebo Comparator: Placebo<br>consume 2 sachet per day for 4 weeks | Dietary Supplement: Placebo<br>* consume 2 sachet per day for 4 weeks<br>|
| Experimental: Banana peel extract<br>consume 2 sachet per day for 4 weeks | Dietary Supplement: Banana peel extract<br>* consume 2 sachet per day for 4 weeks<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Blood pressure | Blood pressure measurement via automatic sphygmomanometer | at 4 week after taking test sample | 
| Total-Cholesterol | Venous blood was sampled to measure concentrations of total-Cholesterol | at 4 week after taking test sample | 
| Triglyceride | Venous blood was sampled to measure concentrations of triglyceride | at 4 week after taking test sample | 
| HDL-C | Venous blood was sampled to measure concentrations of HDL-C | at 4 week after taking test sample | 
| LDL-C | Venous blood was sampled to measure concentrations of LDL-C | at 4 week after taking test sample | 
| Sleep monitoring | Detect the electrical activity of the heart in the potential difference between two specific points on the body surface to reflect the state of sleep | at 4 week after taking test sample | 
| Serotonin | Venous blood was sampled to measure concentrations of Serotonin | at 4 week after taking test sample | 
| Melatonin | Venous blood was sampled to measure concentrations of Melatonin | at 4 week after taking test sample |