The Effect of Circuit Exercise Program in Gestational Diabetes

Study Overview
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Brief Summary
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Gestational diabetes (GDM) is defined as 'pregnancy-onset or first noticed glucose intolerance'. The aim of this study is to investigate the effect of circuit exercise program applied in addition to diet therapy on cognitive function, functional exercise capacity, mobility, depression and quality of life in women with gestational diabetes. 60 female participants between the ages of 18-35 who meet the inclusion criteria will be included in the study. Participants will be randomly divided into 2 groups as diet group (n=30) and exercise group (n=30). All participants will receive GDM-specific dietary therapy for 6 weeks. In addition to diet therapy, individuals in the exercise group will be given a circuit exercise program for 6 weeks. Participants will be evaluated for blood values, cognitive status and functionality at the baseline and 6 weeks later.

Official Title
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The Effect of Circuit Exercise Program on Cognitive Function, Functional Exercise Capacity, Mobility, Depression and Quality of Life in Women With Gestational Diabetes

Conditions
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Gestational Diabetes

Intervention / Treatment
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* Other: Diet
* Other: Exercise


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: being diagnosed with gestational DM being between the ages of 18-35 being in 24-32 weeks of pregnancy being inactive physical activity level - (<300 MET weeks/day) Exclusion Criteria: Diagnosed with diabetes before pregnancy have given birth before Multiple Pregnancy (>2) Intrauterine growth restriction Preeclampsia having high risk of preterm labor and on strict bed rest treatment with insulin or oral hypoglycemic agents during pregnancy Other significant severe or poorly controlled medical conditions (thyroid disease, cardio-respiratory disorders, ...) taking medications that affect cognitive function, including corticosteroids, anti-depressants, or anti-epileptics

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 35 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Diet Group<br>Individuals will receive only dietary treatment that the dietitian deems appropriate for 6 weeks. | Other: Diet<br>* Special diet program for gestational diabetes<br>|
| Experimental: Exercise Group<br>In addition to the 6-week diet program that the dietitian deems appropriate, a circuit exercise program will be applied for 6 weeks. The circuit exercise program will consist of a medium-intensity circuit training for 50 minutes, 3 days a week, detailing the main muscle groups of the patients (chest, back, biceps, triceps, deltoid, quadriceps, thigh and calf muscles). Exercise intensity will be monitored using Borg's scale of perceived exertion, with a target intensity of 12 to 14. 8 exercises will be given in a continuous, circuit-type manner with short 1-minute rests. | Other: Diet<br>* Special diet program for gestational diabetes<br>Other: Exercise<br>* The circuit exercise program will consist of a medium-intensity circuit training for 50 minutes, 3 days a week, detailing the main muscle groups of the patients (chest, back, biceps, triceps, deltoid, quadriceps, thigh and calf muscles). Exercise intensity will be monitored using Borg's scale of perceived exertion, with a target intensity of 12 to 14. 8 exercises will be given in a continuous, circuit-type manner with short 1-minute rests.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Blood count test 1 | Fasting blood glucose (FBG) value will be recorded. | 6 weeks after baseline | 
| Blood count test 2 | Postprandial blood glucose (PBG) value will be recorded. | 6 weeks after baseline | 
| Blood count test 3 | HbA1c value will be recorded. | 6 weeks after baseline | 
| Blood count test 4 | Total cholesterol (T-col) value will be recorded. | 6 weeks after baseline | 
| Blood count test 5 | High-density lipoprotein cholesterol (HDL) value will be recorded. | 6 weeks after baseline | 
| Blood count test 6 | Low-density lipoprotein cholesterol (LDL) value will be recorded. | 6 weeks after baseline | 
| Blood count test 7 | Insulin value will be recorded. | 6 weeks after baseline | 
| Blood count test 8 | Triglyceride (TG) value will be recorded. | 6 weeks after baseline | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Montreal Cognitive Assessment Scale | It is a screening scale developed to evaluate the early stages of cognitive impairment. Min score is 0, max score is 30. High scores mean a better outcome. | 6 weeks after baseline | 
| WMS Number Range Test | In the forward number range, the patient is asked to repeat the numbers told to her in the same order, and in the backward number range, the patient is asked to repeat the said numbers from the end to the beginning. High scores mean a better outcome. | 6 weeks after baseline | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Gestational diabetes, Circuit Exercise, Cognition