Comparison of BiPAP and ٰIS in Reducing Post CABG Pulmonary Complications

Study Overview
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Brief Summary
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To evaluate the effect of Bi-level Positive Airway Pressure (BiPAP) and Incentive Spirometry (IS) in post CABG patients.

Detailed Description
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As postoperative pulmonary complications are major concern in cardiac surgery patients and our local data is deficient for making better management guidelines. My study aims to provide a base for future research on this dimension and to decide better management plan for post cardiac surgical pulmonary complications. The hypothesis is Post extubation BiPAP is more effective than Incentive Spirometry (IS) in reducing postoperative pulmonary complications in cardiac surgical patients and the purpose of the study is to evaluate the effect of Bi-level Positive Airway Pressure (BiPAP) and Incentive Spirometry (IS) in cardiac surgical patients. This Randomized Controlled Trial (RCT) study will be conducted at Chaudhary pervaiz elahi institute of cardiology ICU multan. A sample size of 350 patients will be taken and effect of BiPAP and Incentive spirometry will be studied in reducing pulmonary complications post CABG surgery. Data will be analyzed through SPSS. For quantitative variables, mean and standard deviation will be calculated and for qualitative variables, frequency and percentage will be calculated. Chi square test will be used to estimate association between qualitative variables. A p value < 0.05 will be significant.

Official Title
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Comparison of Effectiveness of Bilevel Positive Airway Pressure and Incentive Spirometry in Reducing Post CABG Surgery Pulmonary Complications

Conditions
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Pulmonary Complications

Intervention / Treatment
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* Device: BiPAP
* Device: Incentive spirometry


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: CABG patients Patient willing to study Patients planned for on-pump cardiac surgical procedures Both genders (Male & Female) Age 20-60 years Ejection fraction 40-60% Exclusion Criteria: Patients with valvular lesions Off-pump cardiac surgery Refusal to give consent for BiPAP Emergency surgery Previous cardiac surgery Obesity BMI>30 ASA status V

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Group 01 Effectiveness of BiPAP in reducing post CABG pulmonary complications<br>Bilevel positive airway pressure device after every 6 hours | Device: BiPAP<br>* To give bilevel positive airway pressure to the lungs<br>* Other names: Bilevel;|
| Active Comparator: Group 02 Effectiveness of IS in reducing post CABG pulmonary complications<br>Incentive spirometry for 15 minutes after every 4 hours | Device: Incentive spirometry<br>* IS for 15 minutes after every 4 hours<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Post CABG pulmonary complications | To see the effect of BiPAP and IS in reducing post CABG pulmonary complications | 06 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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IS, CABG, BiPAP