The Fluid Translation of Research Into Practice Study

Study Overview
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Brief Summary
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Translating reliable evidence on fluid resuscitation of intensive care patients into clinical practice - Improving patient outcomes and containing public health costs

Detailed Description
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The Fluid-Translation of Research into Practice Study (TRIPS) is an international, single day, cross-sectional study planned for the second quarter of 2014, coordinated by the George Institute for Global Health, with the purpose of documenting prescribing practices for fluid resuscitation in intensive care units (ICUs) worldwide. This international cross-sectional study follows on from the publication of large-scale randomized controlled trials and meta-analyses of fluid resuscitation, which provide evidence of how fluid resuscitation may affect patient-centered outcomes. Fluid-TRIPS is a repeat of the Saline versus Albumin for Fluid Evaluation (SAFE)-TRIPS which was an international cross-sectional survey conducted in 2007 that had 391 ICU's participate from 25 countries and provided insight into international fluid resuscitation practice at that time. Along with establishing if fluid resuscitation practices have changed since SAFE-TRIPS, Fluid-TRIPS also aims to determine the relationship between fluid choice and evidence, along with understand other factors that may influence the choice of bolus fluid in clinical practice.

Official Title
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The Fluid Translation of Research Into Practice Study (Fluid-TRIPS): An International Cross-Sectional Survey of Fluid Resuscitation Practice

Conditions
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Critical Care, Fluid Resuscitation

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Adult patients present in the ICU on the study day or admitted during the 24-hour study period will be included in the study sample. Exclusion Criteria: Children under 16 years are excluded

Ages Eligible for Study
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Minimum Age: 16 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Adult ICU patient receiving Fluid resus<br>Adult patients present in the ICU at the start of the study day or admitted during the 24-hour study period will be included in the study sample. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Type of resuscitation fluid in ICU | To describe the amount and type of resuscitation fluid currently administered to adult patients in intensive care units (ICU) in different countries | 24-hour study day | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cost comparison of fluid choice between regions | To describe and compare the costs of fluid choice between different geographical regions | Designated 24-hour study day | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Adult, ICU patient, Fluid resuscitation, observational study