Alcohol and Other Psychoactive Substances in Road Traffic - a Case-control Study

Study Overview
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Brief Summary
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The main purpose of the study is to determine the accident risk when driving under the influence of psychoactive substances, including alcohol (DUI). Other aims are to find out the prevalence of psychoactive substances in road traffic and to obtain information on the role of these substances in road traffic accident causations. For the purposes of the study, drivers of motorised vehicles are randomly stopped and interviewed and breath alcohol is recorded. Also, an oral fluid sample is taken and psychoactive substances are investigated in the laboratory. For cases, drivers injured in traffic accidents are asked to participate to the study. A whole blood sample and, if possible, an oral fluid sample is taken and psychoactive substances are determined in the laboratory. Also, people diseased in road traffic accident are included in the study. The information required for these subjects are taken from a register database. The study is part of an EU-project DRUID. Altogether 13 European countries take part to the study.

Official Title
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DRUID Work Package 2 - Epidemiology

Conditions
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Prevalence of Psychoactive Substances in Road Traffic, Psychoactive Substances in Accident Involved Drivers, Relative Risk Estimation of Accident Involvement for Impaired Drivers

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 18 years or older driver of a motorised vehicle or bicycle is willing to participate to the study (not applicable to the diseased drivers; information obtained from a register database) Exclusion Criteria: 17 or younger not the driver of a motorised vehicle or bicycle does not want to participate (not applicable to the diseased drivers; information obtained from a register database)

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| 1<br>randomly stopped drivers of motorised vehicles and bicycles | |
| 2<br>drivers of motorised vehicles and bicycles injured or killed in road traffic accidents | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| relative risk estimation of accident involvement for drivers impaired by psychoactive substances |  | three years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| prevalence of psychoactive substances in the general driving population |  | three years | 
| prevalence of psychoactive substances among accident involved drivers |  | three years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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driving under the influence, psychoactive substances, roadside surveys, hospital surveys, accident involvement risk estimation