linjc16/ctgov huggingface dataset:
Disturbing Factors in the Operating Room

Study Overview
=================
Brief Summary
-----------------
Observation of disturbing factors in the operating room and comparison between day and night shift. The investigators have chosen to observe kidney transplantations, since this type of operation has the same priority during day and night. Stress levels of surgeons will be measured using the HealthPatch.

Official Title
-----------------
Disturbing Factors and Stress Levels in Vascular Surgeons During Kidney Transplantations

Conditions
-----------------
Stress, Disturbing Factors

Intervention / Treatment
-----------------
* Device: HealthPatch


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: All vascular surgeons who are able to perform elective as well as postmoral kidney transplantations Exclusion Criteria: -

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Kidney transplantation, postmortal, day<br> | Device: HealthPatch<br>* Smart patch that is able to measure stress real time using an algorithm between HR and HRV<br>|
| Kidney transplantation, postmortal, night<br> | Device: HealthPatch<br>* Smart patch that is able to measure stress real time using an algorithm between HR and HRV<br>|
| Kidney transplantation, living donor<br> | Device: HealthPatch<br>* Smart patch that is able to measure stress real time using an algorithm between HR and HRV<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Factors that are disturbing for vascular surgeons during kidney transplantations | One investigator will report all factors that potentially disturb the vascular surgeon during kidney transplantation. Nature and severity of the disturbing factors will be reported, such as opening and closing of doors, beepers. For this, the investigators will use an observational tool for assessing surgical flow disruptions (Parker SE, et al. Development and evaluation of an observational tool for assessing surgical flow disruptions and their impact on surgical performance. World J Surg 2010; 34(2): 353-361) | 2 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Stress levels | Stress levels, measured by the HealthPatch | 2 hours | 
| State Trait Anxiety Inventory | STAI; anxiety questionnaire | 5 minutes |
Changing Of Egyptian Population Behaviour Towards COVID 19 Outbreak

Study Overview
=================
Brief Summary
-----------------
During the COVID-19 pandemic, the Egyptian government issued movement restrictions and placed areas into quarantine to reduce the spread of the disease. In addition, individuals were encouraged to adopt personal protective measures, such as social isolation , increasing personal hygiene and wearing protective face masks. Information regarding the COVID 19 virus and protective measures is found on social media and ministry of health website and a number of the Egyptian population are keeping track of them .Public Awareness play a major rule in reducing the spread of COVID 19 so in this study a survey is done to measure the awareness of the Egyptian population toward COVID 19 , their knowledge and attitude and their adherence to preventive measures.It also measures the change of their behavior during the beginning of the outbreak and after a few months of the outbreak in Egypt.

Detailed Description
-----------------
Detailed Description: The survey will enroll as many individuals of the Egyptian population as possible in the survey portion of the study - The number of participates have no limitations, at least 700 participants. The survey will be enrolled in online google form, face to face interview(this will be reduced to encourage social isolation) & semi-structured telephone interviews if possible. The research procedures: An online survey link will include questions regarding the awareness of the Egyptian population , their knowledge , attitudes and behaviour during covid-19 outbreak.and also a comparison of their behaviour among different time periods of the outbreak Face to face and semi-structured interviews if possible: For those Egyptian citizens who state that they would like to participate in an interview, a random sample will be contacted. Inclusion Criteria: Egyptian population of any age group Exclusion Criteria: none

Official Title
-----------------
Survey Of Egyptian Population Change in Knowledge, Attitude and Behaviour Towards COVID 19 Outbreak

Conditions
-----------------
COVID 19

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Egyptian population of different age groups Exclusion Criteria: none
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| awareness of Egyptian population | evaluate the knowledge , attitude and behaviour and their change among Egyptian population during COVID 19 outbreak. | 6 months |
Swelling or Malrotation of Metacarpal Shaft Fractures in the Evaluation of Rotational Deformity

Study Overview
=================
Brief Summary
-----------------
Rotational deformity or malunion causes the most significant functional deficit in these common fractures. The evaluation of the rotation may be performed with the metacarpophalangeal joints flexed although postoperative swelling may not enable this examination with flexion of the fingers. Furthermore, it has been shown that swelling may cause rotation of the digit itself. The investigators propose that the swelling may cause a mistake in the estimation of rotation, during surgery and early follow up period. This is of special importance when open reduction and rigid fixation is performed. Methods: Prospective analysis of XX isolated metacarpal fractures treated, in YY patients was performed. End-on view of the finger-nail was taken with a digital camera on the day of OR, at 2 weeks and at 1 year. The photos were taken on a standard apparatus and from a distance of XX cm and evaluated using ZZ software in comparison with photos taken of the other hand, according to the involved digit. Range of motion, type of fracture and type of fixation were compared.

Official Title
-----------------
Swelling or Malrotation of Metacarpal Shaft Fractures in the Evaluation of Rotational Deformity

Conditions
-----------------
Metacarpal Shaft Fractures

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: isolated metacarpal fractures in one hand- fingers 2, 3, 4, 5 treated with cast or surgical treatment , closed or open reduction Exclusion Criteria: multiple fractures simultaneously fractures in both hands former fracture in one of the fingers, two palms,metacarpal,proximal phalanx (with exception of the thumb) open fracture, open wounds, infection pregnancy, inability performing full x-ray follow up

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 75 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Metacarpal Shaft Fractures<br> | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
Effects of Whey Protein Intervention on Body Composition and Muscle Function in the Elderly With Sacropenia

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to compare the effects of different dose of whey protein intervention(in a daily dose of 0g, 10g, 20g) on lean body mass,body fat composition and muscular function state in the elderly with sacropenia.

Official Title
-----------------
A Double-blind Randomized Controlled Study About the Effects of Whey Protein Intervention on Body Composition and Muscular Function in the Elderly With Sacropenia

Conditions
-----------------
Healthy

Intervention / Treatment
-----------------
* Dietary Supplement: protein supplement


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: People aged over 65 years. Usual gait speed less than 0.8m/s. Willing to participate in the study, consume the test product and perform all measurements. Exclusion Criteria: nervous system disease. Other diseases with movement disorder such as stroke,fracture,arthritis. people who unconsciousness and can not complete questionnaire long-term regular use of protein and antioxidant.

Ages Eligible for Study
-----------------
Minimum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: whey protein<br>2 x 10g whey protein per day orally for 6 months | Dietary Supplement: protein supplement<br> <br> |
| Other: whey protein+soy protein<br>10g whey protein + 10g soy protein per day orally for 6 months | Dietary Supplement: protein supplement<br> <br> |
| Other: soy protein<br>2 x 10g soy protein per day orally for 6 months | Dietary Supplement: protein supplement<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| lean body mass | At baseline, 3 and 6 months, investigators will use DXA to examine lean body mass and body fat composition | up to 6 months | 
| muscular function state | At baseline, 3 and 6 months, investigators will use the Short Physical Performance Battery (SPPB) to test muscular function state | up to 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| plasma amino acid spectrum, especially branched chain amino acid spectrum | At baseline and 6 months, blood samples will be drawn and plasma amino acid spectrum, especially branched chain amino acid spectrum will be tested | up to 6 months |
Detection of Human Papillomavirus in Polymerase Chain for Suspicious Lesions of the Amygdala: Concordance Smear-Biopsy

Study Overview
=================
Brief Summary
-----------------
Multicentre prospective study of concordance between two tissue sampling modes (smear / biopsy), which applies the same diagnostic method (PCR).

Official Title
-----------------
Detection of Human Papillomavirus in Polymerase Chain for Suspicious Lesions of the Amygdala: Concordance Smear-Biopsy

Conditions
-----------------
Human Papillomavirus

Intervention / Treatment
-----------------
* Procedure: Tonsil Biopsy
* Procedure: Smear


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Presents a suspicious lesion of the amygdala region Have a biopsy of the oropharynx planned in the operating room. Exclusion Criteria: Pregnant Patient. Against anesthetic or surgical indication for endoscopy of the upper aerodigestive tract.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: patient with suspected lesions of the tonsillar region<br>patients will have a tonsil biopsy and a smear | Procedure: Tonsil Biopsy<br>* Biopsies were obtained during endoscopy of Aero-Digestive Tract Superior under general anesthesia.<br>Procedure: Smear<br>* The smears are made in consultation a fortnight before performing endoscopic examination. They are carried out after a local anesthetic spray in order to optimize the number of cells collected.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the correlation between the two sampling methods | the correlation between the two sampling methods (smear and biopsy), defined by the probability of positive correlation and the negative concordance probability. | 1 month | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| rate of concordance for the detection of HPV between biopsy and smear |  | 1 month | 
| the overall agreement | the overall agreement, assessed by kappa Cohen. | 1 month | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Human Papillomavirus, oropharynx biopsy, tonsillar lesion
Application of Megavoltage Imaging to Reduce Artifact After Seed Implants

Study Overview
=================
Brief Summary
-----------------
This is a non-randomized study to evaluate the utility of MVCT as a quality assurance measure in patients treated with interstitial permanent seed implants for low and intermediate risk prostate cancer. All patients will received the same standard of care treatment but will receive an additinoal CT image of the prostate.

Official Title
-----------------
Application of Megavoltage Imaging to Reduce Artifact Following Interstitial Seed Implants for Prostate Adenocarcinoma

Conditions
-----------------
Prostate Cancer

Intervention / Treatment
-----------------
* Radiation: MVCT


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Male 50-80 years of age Eligible for interstitial brachytherapy implants Exclusion Criteria: -

Ages Eligible for Study
-----------------
Minimum Age: 50 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
Male

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| MVCT<br>Patients will receive an additional MVCT scan at their one month follow up visit. | Radiation: MVCT<br>* Patients will receive an additional MVCT scan at their one month follow up visit.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in prostate volume measured in cm^3 | Change in prostate volume measured with trans-rectal ultrasound at baseline versus prostate volume measured with KVCT and MVCT. | One month post implant | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Prostate, Cancer
Cognitive Effects of Citicoline in Men and Women With Age-Associated Memory Impairment

Study Overview
=================
Brief Summary
-----------------
The objective of this trial is to determine the effects of citicoline on cognitive performance in healthy Men and Women with Age-Associated Memory Impairment compared to a placebo.

Detailed Description
-----------------
This study is a 12-week, randomized, double-blind, placebo-controlled trial of citicoline in healthy men and women with Age-Associated Memory Impairment. Cognitive assessments will be performed to determine whether citicoline administration with supportive memory, compared to placebo administration.

Official Title
-----------------
A Parallel, Double-Blind Study to Assess the Cognitive Effects of a Citicoline Supplement (Cognizin®) in Men and Women With Age-Associated Memory Impairment

Conditions
-----------------
Healthy

Intervention / Treatment
-----------------
* Dietary Supplement: Placebo supplement
* Dietary Supplement: Citicoline supplement


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: male or female, 50-85 years of age at least a high school diploma or the equivalent self-reported memory loss scores ≥24 on the Mini-Mental State Examination, ≥85 on the Kaufman Brief Intelligence Test, Second Edition, ≤5 on the Geriatric Depression Scale, and 4, 3, or 2 on the Spatial Span Test no health conditions that would prevent him or her from fulfilling the study requirements on the basis of medical history and routine laboratory test results Exclusion Criteria: color blind abnormal laboratory test results major medical or neurological illness female who is pregnant, planning to be pregnant during the study period requiring treatment with a drug which might obscure the action of the study treatment

Ages Eligible for Study
-----------------
Minimum Age: 50 Years
Maximum Age: 85 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Placebo Comparator: Placebo<br> | Dietary Supplement: Placebo supplement<br>* Cellulose<br>* Other names: Placebo;|
| Experimental: Cognizin<br> | Dietary Supplement: Citicoline supplement<br>* Cognizin<br>* Other names: Cognizin;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Standardized scores on the Cambridge Brain Sciences that measure cognitive assessment |  | 12 weeks |
Quantification of Hepatic Fibrosis by IVIM Sequences in 1.5T MRI

Study Overview
=================
Brief Summary
-----------------
Quantification of hepatic fibrosis by IVIM sequences in 1.5T MRI.

Detailed Description
-----------------
Early and accurate diagnosis of hepatic fibrosis in patients with chronic liver disease is essential and essential. This assessment could be performed by a non-invasive MRI method. The main objective of this study is to show that the measured perfusion-related scattering value (D *) is related to the hepatic fibrosis stage. Secondary objectives Evaluation of infusion fraction (f) and fibrosis stage. Evaluation of molecular diffusion (D) and fibrosis stage. Evaluation of ADC and fibrosis stage. Assess whether there is a link between the etiology of fibrosis and the value of the diffusion.

Official Title
-----------------
Quantification of Hepatic Fibrosis by IVIM Sequences in 1.5T MRI.

Conditions
-----------------
MRI, Liver Fibrosis, IVIM, Liver Biopsy

Intervention / Treatment
-----------------
* Procedure: Quantification of liver fibrosis


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients undergoing hepatic biopsy (trans-parietal or trans-jugular) in the context of liver disease Signature of written consent Exclusion Criteria: Contra-indications to MRI Refusal of protocol Underage patients and protected adults

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 100 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Patients with hepatic biopsy<br>The patients having benefited from a hepatic biopsy for evaluation of the hepatic fibrosis, will benefit in 10 days of a MRI in the service of radiology of the hospital Gabriel Montpied. | Procedure: Quantification of liver fibrosis<br>* Procedure MRI and liver biopsy<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Measured perfusion-related scattering value | The main objective of this study is to show that the measured perfusion-related scattering value (D *) is related to the hepatic fibrosis stage. | at day 1 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Measured perfusion-related of infusion fraction |  | at day 1 | 
| Measured perfusion-related of molecular diffusion |  | at day 1 | 
| Measured perfusion-related of ADC |  | at day 1 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Hepatic fibrosis, IVIM, 1.5T MRI
Observational Study of Anti-Cancer Therapy Induced Oral Mucositis in Korean Cancer Patients

Study Overview
=================
Brief Summary
-----------------
to survey oral mucositis after chemotherapy and Concurrent chemoradiotherapy in Korean cancer patients

Official Title
-----------------
Observational Study of Anti-Cancer Therapy Induced Oral Mucositis in Korean Cancer Patients

Conditions
-----------------
Oral Mucositis

Intervention / Treatment
-----------------
* Other: no intervention study


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients diagnosed with one cancer among head and neck cancer, esophageal cancer, breast cancer, colorectal cancer, gastric cancer, and non-small cell lung cancer, who are being treated or going to be treated as one between A and B A. Chemotherapy only B. Concurrent chemoradiotherapy Exclusion Criteria: Patients who are pregnant or breast feeding, absent from effective(medically proven) contraceptive method for females of childbearing potential Patients with performance status of ECOG score is more than 3

Ages Eligible for Study
-----------------
Minimum Age: 19 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: no intervention study|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| incidence and severity of oral mucositis |  |  |