Epidemiology of Acute Self-poisoning in Emergency Services in France

Study Overview
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Brief Summary
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Acute self poisoning is a leading cause of suicide attempts and leads to frequent emergency department visits. However, the exact epidemiology of acute self poisoning is not known. The description of the clinical pathway and the characteristics of patients with acute self poisoning could lead to an improvement in emergency care. The Investigators will conduct a 48h observational study in emergency services in France. Investigators primary objective is to gathered epidemiological clinical and treatment data during emergency dispatch, prehospital care and inhospital emergency care.

Detailed Description
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Acute self poisoned patients will be prospectively and anonymously recruited by emergency physicians in charge during two days. Acute self poisoning is define as follow: intentional medicine intake in the 24h hours before emergency department admission. Epidemiological, clinical, toxicological and treatment data will be gathered. Outcome of patient will be prospectively assessed at 30days. All data will be transmitted to the principal investigators. Then, 20% of the data will be monitored by an independent committee. Exhaustivity will be retrospectively assessed by the number of inclusions in 10 emergency centers divided by the total number of possible inclusions in these centers. Finally, an independent statistician will be in charge of the analysis.

Official Title
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Evaluation of the Epidemiology and the Take Load of Voluntary Drug Intoxications by the Emergency Structures in France

Conditions
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Suicide Attempts

Intervention / Treatment
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* Other: No intervention


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: acute self poisoning defined as the intentional intake (oral, nasal, injection etc.) of medicines during the 24h before first medical contact Exclusion Criteria: cardiac arrest at first medical contact (dispatch or physician) acute self poisoning without any medication intake non intentional poisoning
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: No intervention|No intervention is planned|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Percentage of each drug class |  | 48h | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| odds ratio of drug classes according to sexe and age |  | 48h | 
| number of participants with poisoning incident |  | 48h | 
| prehospital and inhospital mortality |  | 30 days | 
| percentage of each antidotal treatment |  | 48h | 
| mobile intensive care unit (percentage) dispatch |  | 30 days | 
| Age according to drug classes ingestion | Median age compared according drug classes ingestion | 48h | 
| Gender according to drug classes ingestion | Pourcentage of gender compared according drug classes ingestion | 48h | 
| Time (median) of admission according to drug classes ingestion |  | 48h | 
| Time (median) of admission according unit of admission |  | 48h | 
| Mortality according to drug class ingestion |  | 30 days | 
| ICU admission according to drug class ingestion |  | 30 days | 
| icu admission (percentage) |  | 48h | 
| percentage of errors according to the Grenoble clinical decision rule |  | 30 days | 
| multivariate analysis to describe factors associated with ICU admission |  | 30 days | 
| multivariate analysis to describe factors associated with mobile intensive care unit dispatch |  | 30 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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emergency department, epidemiology, prehospital care, dispatch, acute self poisoning