Follicular Flushing Outcomes in Singles Versus Double Lumen Oocyte Retrieval Needles in Poor Responding Patients

Study Overview
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Brief Summary
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In this study, the investigators aimed to evaluate to the efficacy of the needle type used in follicular flushing in oocyte retrieval in the poorest responders undergoing IVF.

Detailed Description
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This study will include: women with less than four follicles on the day of hCG administration women between 20-45 age old The value of progesterone on the day of hCG administration will be under 1.5ng/ml

Official Title
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Follicular Flushing Outcomes in Singles Versus Double Lumen Oocyte Retrieval Needles in Poor Responding Patients:a Randomized Controlled Trial

Conditions
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Infertility

Intervention / Treatment
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* Procedure: single lumen needle in oocyte retrieval
* Procedure: double lumen needle in oocyte retrieval


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: women between 20-45 years old the number of follicles less than 5 on the day of HCG administration the value of progesteron on the day of hCG administration must be under 1.5ng/ml Exclusion Criteria: women under 20 years and older than 45 year on the day of hCG administration if the follicle number is more than 5 if.the value of progesteron on the day of hCG administration is higher than 1.5ng/ml

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 45 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: single lumen<br>Single lumen needle in oocyte retrieval | Procedure: single lumen needle in oocyte retrieval<br>* single lumen needle use during oocyte retrieval<br>Procedure: double lumen needle in oocyte retrieval<br>* after aspiration of follicles, 3 times flushing will be performed in double lumen needle.<br>|
| Active Comparator: double lumen<br>Double lumen needle with follicle flushing during oocyte retrieval | Procedure: single lumen needle in oocyte retrieval<br>* single lumen needle use during oocyte retrieval<br>Procedure: double lumen needle in oocyte retrieval<br>* after aspiration of follicles, 3 times flushing will be performed in double lumen needle.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| number of metaphase 2 oocyte |  | Six months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| clinical pregnancy rate |  | eigth months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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IVF, follicular flushing, poor responders, oocyte retrival