Effect of Preoperative Oral Carbohydrate Administration in Thoracic Surgery Patients

Study Overview
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Brief Summary
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Preoperative carbohydrate loading has been shown to reduce pre-operative discomfort and postoperative nausea and vomiting. There is no need for prolonged preoperative fasting of the patients, but the traditional approach still continues especially in thoracic surgery patients. For this purpose, we aimed to evaluate the effect of preoperative carbohydrate loading on postoperative morbidity in the patients.

Detailed Description
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The study was conducted on 94 patients. The patients in the control group were fasting after midnight. Experimental group patients consumed carbohydrate drink as liquid two hours before the operation. 47 patients were in the control group (A) and 47 patients were in the experimental group (B). The groups were compared in terms of length of hospital and intensive care unit stay, vomiting, gas-stool outlet, postoperative pain conditions (VAS), inflammation parameters, blood glucose, and mobilization time. SPSS 11.0 (SPSS, Inc., Chicago, IL, USA) was used for statistical analyses. All means were presented with 95% confidence limits. In the empirical analysis, t-test and chi-square test were used. In addition, correlation analysis was used to determine the relationship between fasting time and surgical recovery time.

Official Title
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Effect of Preoperative Oral Carbohydrate Administration in Thoracic Surgery

Conditions
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Non Small Cell Lung Cancer, Fasting, Postoperative Pneumonia

Intervention / Treatment
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* Dietary Supplement: Oral carbohydrate


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Stage I-Stage II all operable NSCLC patients - Exclusion Criteria: Patients with diabetes mellitus, a history of delayed gastric emptying, severe hepatic or renal failure, or any endocrine disorder that might influence the metabolic parameters were excluded, as were patients requiring urgent or emergent surgery. -

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: oral carbohydrate<br>the patients drunk oral carbohydrate two hours ago preoperatively | Dietary Supplement: Oral carbohydrate<br>* 100 ml oral carbohydrate two hours ago preoperatively<br>|
| No Intervention: no oral carbohydrate<br>the patients did not drink oral carbohydrate preoperatively | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Mobilization time | postoperative mobilization | 1 hour | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Preoperative fasting, postoperative morbidity, preoperative carbohydrate drinking, thoracic surgery