Tackling Intrusive Traumatic Memories After a Difficult Birth

Study Overview
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Brief Summary
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This proof-of-principle study aims to investigate the effects of a brief behavioural procedure including a computerized visuospatial task (the computer game Tetris) preceded by a reactivation of the traumatic memory of childbirth, on birth-related intrusive traumatic memories and other postpartum posttraumatic stress symptoms. Women who report birth-related intrusive memories after 6 weeks postpartum will monitor their intrusive traumatic memories in a daily diary. After two weeks of diary, they will meet a psychologist to briefly evoke the memory of their birth, and receive a brief behavioural procedure including playing Tetris. Participants will then continue to complete an intrusive traumatic memory diary during two weeks. It is predicted that they will report fewer intrusive memories in the two weeks following the intervention, compared to the two weeks before. This will inform the potential future development of a simple computerized intervention procedure to reduce distressing psychological symptoms after traumatic childbirth.

Official Title
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Tackling Intrusive Traumatic Memories After a Difficult Birth: a proof-of Principle Study

Conditions
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Posttraumatic Stress Disorder, Intrusive Traumatic Memories

Intervention / Treatment
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* Behavioral: Brief behavioural procedure including a computerized visuospatial task (computer game Tetris)


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Gave birth at the Lausanne University Hospital Gave written consent Have at least 4 related-to-childbirth intrusions over the two weeks prior to recruitment, and at least 2 related-to-childbirth intrusions during the pre-intervention diary Gave birth more than 6 weeks ago Is able to distinguish intrusions linked to the traumatic childbirth from intrusions linked to other traumatic events Exclusion Criteria: Gave birth to a stillborn child Not fluent in French Severe illness of mother or infant (e.g. cancer, cardiovascular disease, severe neurodevelopmental difficulties, malformations) Have an established intellectual disability, or psychiatric history such as psychotic illness Alcohol abuse and/or illegal drug use Currently receiving psychological care in relation with the traumatic birth experience

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Interventional Model Description: Single group pre-post study
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Intervention<br> | Behavioral: Brief behavioural procedure including a computerized visuospatial task (computer game Tetris)<br>* Brief behavioural procedure including a computerized visuospatial task (the computer game Tetris) preceded by a reactivation of the traumatic memory of childbirth<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Frequency of intrusive memories of the index trauma | Frequency of intrusive traumatic memories related to childbirth recorded by participants in a trauma-related intrusive memories diary over the two weeks after the intervention | Within 2 weeks following the intervention | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Presence and severity of maternal PTSD symptoms | PTSD Checklist (PCL-5) for DSM-5 | 1 month after the intervention | 
| Frequency of intrusive memories of the index trauma | Frequency of intrusive traumatic memories related to childbirth recorded by participants in a trauma-related intrusive memories diary between the 4th and 6th weeks following the intervention | Between 4 and 6 weeks after the intervention | 
| Psychological distress related to intrusive memories of the index trauma | Rating scale for psychological distress related to intrusive memories related to childbirth that are reported in an intrusive memories diary over the two weeks after the intervention. It is a SUDS (Subjective Units of Distress Scale) from 1 to 10 (1= No distress at all while having the intrusion ; 10 = Extreme distress while having the intrusion). | Within 2 weeks following the intervention |