Perioperative Management of Patients With Coronary Stents Undergoing Noncardiac Surgery

Study Overview
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Brief Summary
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The purpose of this study is to evaluate and monitor perioperative management of patients with coronary stents undergoing noncardiac surgery. Objectives: To describe the incidence and severity of adverse cardiovascular events in patients with coronary stents undergoing noncardiac surgery with admission. To assess the following-up of the guidelines about the perioperative management of antiplatelet therapy in these patients. To assess the relationship between the incidence of cardiac or neurovascular events, as well as bleeding complications with the perioperative management of antiplatelet therapy. Number of Participants with Adverse Events as a Measure of Safety

Detailed Description
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(Not desired)

Official Title
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Evaluation and Monitoring of Perioperative Management of Patients With Coronary Stents Undergoing Noncardiac Surgery

Conditions
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Acute Coronary Syndrome, Coronary Stent Occlusion, Surgery

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: > 18 years old, with coronary stents American Society of Anaesthesia physical status II-V noncardiac surgery wiht admission informed consent Exclusion Criteria: < 18 years old American Society of Anaesthesia physical status I ambulatory surgery pregnancy obstetric anaesthesia endoscopic procedures cardiac surgery not informed consent

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Coronary Stent<br>Patients with coronary Bare Metal Stent (BMS) or Drug Eluting Stent (DES) undergoing noncardiac surgery | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Major Adverse Cardiac and Cerebrovascular Events (MACCEs) | Cardiac Mortality, Myocardial Infarction, Angina Pectoris, new arrythmia, Congestive Heart Failure, Stroke, Cardiac Arrest | up to 90 days after surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Major Haemorrhagic Events | Transfusion > = 2 red blood cells Units, haemoglobin descent >= 20 gr/dL, intracerebral haemorrhage | up to 90 days after surgery | 
| Number of Patients With Adverse Events Related With Antiplatelet Therapy Management | Perioperative withdrawal antiplatelet therapy is defined with > or = 5 days without therapy We create 3 categories: Not withdrawal Complete withdrawal (5 or > days without antiplatelet drugs , mono or dual therapy) Incomplete withdrawal: patients under dual antiplatelet therapy, who maintain aspirin and stopped clopidogrel =/ > 5 days | 90 days after surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Coronary Stent, BMS stent, DES stent, Date of stent implantation, cardiac event, neurovascular event, Bleeding, transfusion