Clinical Utility of Intraoperative Parathyroid Scores System in Thyroidectomy

Study Overview
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Brief Summary
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Ready to establish the Intraoperative Parathyroid Scores System (IPSS) for thyroidectomy and study the clinical value of Intraoperative Parathyroid Scores System for thyroidectomy.

Detailed Description
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IPSS includes transplantation Parathyroid Scores and in situ Parathyroid Scores, the investigators will establish the Intraoperative Parathyroid Scores System by parathyroid size and Blood supply, and recording IPSS, according to certain rules. Parathyroid hormone and calcium were test in d0, d1, d14, d60 post operation. The correlation between Intraoperative Parathyroid Scores and PTH calcium were calculated, and ROC curve and logistic regression were tested for the prediction value.

Official Title
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Clinical Utility of Intraoperative Parathyroid Scores System in Thyroidectomy

Conditions
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Intraoperative Parathyroid Scores System

Intervention / Treatment
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* Procedure: Different range of thyroid surgery


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: postoperative pathology confirmed as thyroid papillary carcinoma; for the first time to undergo thyroid surgery, no history of neck surgery and external radiotherapy; preoperative serum calcium, parathyroid hormone levels were normal; intraoperative and postoperative clinical data integrity, standardized follow-up patients; parathyroid is a tumor violation. Exclusion Criteria: serious underlying disease; age greater than 60 years of age or combined with arteriosclerotic disease; patients with postoperative loss; patients with parathyroid disease.

Ages Eligible for Study
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Maximum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Total thyroidectomy<br>Patients need to do total thyroidectomy According to guidelines | Procedure: Different range of thyroid surgery<br>* Observe and record parathyroid status during thyroid surgery<br>|
| Hemithyroidectomy<br>Patients need to do Hemithyroidectomy According to guidelines | Procedure: Different range of thyroid surgery<br>* Observe and record parathyroid status during thyroid surgery<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| transplantation Parathyroid Scores correlated with transplanted parathyroid function | relation with transplantation Parathyroid Scores and transplanted parathyroid hormone | 2014-2016 | 
| the value of IPSS and in situ Parathyroid Scores | relation with Intraoperative Parathyroid Scores and in situ Parathyroid Scores | 2014-2016 | 
| predicted function of IPSS | IPSS and in suit PSS be recoded and D1，D14 PTH Ca2+ were tested | 2014-2016 | 
| value of IPSS in low PTH patients | IPSS and in suit PSS be recoded and D1，D14 PTH Ca2+ were tested | 2014-2016 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| value of IPSS for Surgeon and patient | description the clinic value | 2014-2016 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Intraoperative Parathyroid Scores System, total thyroidectomy, thyroid cancer, hypoparathyroidism, prediction