Exercise Intervention on Conflict Monitoring in Children With Attention-deficit Hyperactivity Disorder

Study Overview
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Brief Summary
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The study mainly investigates the effect of high-intensity interval training on conflict monitoring in children with ADHD by using event-related potential and sLORETA techniques.

Detailed Description
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The present study will have two experiments, one is a cross-section study and the other is intervention study. As for cross-section study, typical developmental children and children with ADHD will perform the stroop task while recording their brain waves. The intervention is twice a week for 5 weeks and before and after the intervention, children with ADHD will randomly assign to either an exercise group or control group. They will perform the stroop task while recording their brain waves.

Official Title
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The Effect of Long-term High-intensity Interval Training on Conflict Monitoring in Children With ADHD: an ERP and sLORETA Study

Conditions
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Exercise Intervention

Intervention / Treatment
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* Other: High-intensity interval training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: age between 7 and 12 years diagnosed with ADHD by a pediatric psychiatrist, which is not required for TD no history of brain injury or neurological conditions, such as exhibited epileptic seizures, serious head injuries, and periods of unconsciousness. Exclusion Criteria: cannot follow the instruction cannot complete all the procedure

Ages Eligible for Study
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Minimum Age: 7 Years
Maximum Age: 12 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Exercise group<br>The group will receive twice a week for 5 week | Other: High-intensity interval training<br>* 2 times weekly for 5 weeks Circuit training with 4 stations<br>|
| No Intervention: Control group<br>The group will be maintained their normal after school activities | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Behavioral performance | reaction time (ms) is generated by computerized task deﬁned as correct responses within the range from 200-1500 ms | Day 0 and post-intervention at Week 5 | 
| Behavioral performance | response accuracy (percentage) is generated by computerized task defined as percentage of trials that successfully responded to target stimulus | Day 0 and post-intervention at Week 5 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| N2 & P3 components | Electroencephalographic (EEG) activity will be measured at 64 sites. The amplitude of the N2 is deﬁned as the mean amplitude within a 50-ms interval surrounding the maximal negative peak within a 200- to 400-ms latency window. The amplitude of the P3 is deﬁned as the mean amplitude within a 50-ms interval surrounding the maximal positive peak within a 300- to 800-ms latency window. | Day 0 and post-intervention at Week 5 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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HIIT, executive function, ADHD, chronic exercise