Effect of Smoking Cessation on Non-surgical Periodontal Therapy

Study Overview
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Brief Summary
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The aim of this prospective study is to verify the efficacy of smoking cessation on non-surgical periodontal therapy in adult subjects with chronic periodontitis. Smokers that were willing to quit received periodontal treatment and concurrent smoking cessation therapy. Periodontal maintenance was performed every 3 months. A calibrated examiner, blinded to smoking status, assessed periodontal status, gathered demographic and behavioural information with a structured questionnaire and measured air carbon monoxide concentration measurements.

Official Title
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Effect of Smoking Cessation on Non-surgical Periodontal Therapy

Conditions
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Periodontitis

Intervention / Treatment
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* Behavioral: Smoking cessation therapy
* Procedure: Non-surgical periodontal therapy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: subjects were willing to stop smoking >10 teeth periodontitis (30% or more of their teeth with proximal CAL ≥ 5 mm Exclusion Criteria: systemic conditions considered as risk factors for periodontal disease, periodontal therapy in the last 6 months continuous systemic use of anti-inflammatory or steroidal drugs

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Adjunctive smoking cessation<br>non-surgical periodontal therapy and concurrent smoking cessation therapy | Behavioral: Smoking cessation therapy<br>* Multidisciplinary smoking cessation therapy, performed by a team comprising physicians, nurses, a psychologist and dentists. It consisted of four 1-h counselling lectures, psychologist-assisted cognitive behavioural therapy, nicotine replacement therapy and medication (bupropion or varenicline). Smoking cessation motivation was reinforced by dentists at the maintenance sessions, by means of motivational interviewing techniques<br>Procedure: Non-surgical periodontal therapy<br>* full-mouth supra and subgingival scaling and root planing (with curettes and ultrasonic scaler); oral hygiene instruction and motivation and removal of intra-oral plaque retentive factors<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Clinical Attachment Level (millimeters) after 24 months |  | baseline and 24 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Gingival recession (millimeters) after 24 months |  | baseline and 24 months | 
| Change in Pocket depth (millimeters) after 24 months |  | baseline and 24 months | 
| Change in bleeding on probing (percentage of sites with bleeding) after 24 months |  | baseline and 24 months | 
| Change in visible plaque (percentage of sites with visible plaque) after 24 months |  | baseline and 24 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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smoking cessation, tobacco, dental, periodontal