Effects of Lumbopelvic Manipulation on Hip and Knee Neuromuscular Activity

Study Overview
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Brief Summary
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The purpose of this study is to determined if a lower back treatment would change the hip and knee muscle activities in people with and without anterior knee pain. The investigators hypothesized that the lower back treatment may change the hip and knee muscle activities in people with anterior knee pain but not in people without anterior knee pain.

Official Title
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Effects of Lumbopelvic Manipulation on Hip and Knee Neuromuscular Activity in People With and Without Patellofemoral Pain Syndrome

Conditions
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Patellofemoral Pain Syndrome

Intervention / Treatment
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* Other: Lumbopelvic manipulation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria for participants in the patellofemoral pain syndrome group: insidious onset of symptoms of non-traumatic origin pain with patellar facet palpation or compression subjective knee pain rating of at least 3/10 on the pain visual analog scale during at least one of the following activities: ascending stair descending stair kneeling squatting running jumping prolong sitting for more than 20 minutes Exclusion criteria for all participants: history of spine, hip or knee surgery history of hip pathology or other knee condition current significant injury of any lower extremity joints pregnancy sign of nerve root compression osteoporosis or history of compression fracture Age- and gender- matched control participants will be recruited if they have no signs or symptoms of patellofemoral pain syndrome and have none of the exclusion criteria

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 50 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Patellofemoral Pain Syndrome<br>Participants with Patellofemoral Pain Syndrome | Other: Lumbopelvic manipulation<br>* High-velocity-low-amplitude thrust manipulation of the lumbopelvic region<br>|
| Active Comparator: Healthy control<br>Age- and gender-matched participants without Patellofemoral Pain Syndrome | Other: Lumbopelvic manipulation<br>* High-velocity-low-amplitude thrust manipulation of the lumbopelvic region<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Electromyography (EMG) | Electromyography (EMG) onset time of the gluteus maximus, gluteus medius, vastus medialis oblique, and vastus lateralis muscles. | The EMG data will be collected within 48 hours for all participants in both groups. On Day 1, data will be collected twice at baseline. On Day 2, data will be collected before and immediately after as well as 15, 30, and 45 min after the intervention. | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain Visual Analog Scale (VAS) | Pain Visual Analog Scale (VAS) is a 100 mm continuous line between two end-points. The left end-point represents no pain and the right end-point represents the worst pain imaginable. | The Pain Visual Analog Scale (VAS) will be assessed before and 45 min after the lower back treatment (lumbopelvic manipulation) for participants in the patellofemoral pain syndrome group on Day 2 only. |