Does Glidescope Video Laryngoscope is Related to Less Hemodynamic Response?

Study Overview
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Brief Summary
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Laryngoscopy and endotracheal intubation causes significant hemodynamic response and thus presents an increased risk for patients undergoing cardiac bypass surgery. Prevention or reduction of this increment is important for hemodynamic control. In this randomized single blind study, the aim of this study is to compare the hemodynamic responses of two different laryngoscopy techniques with Glidescope and Macintosh laryngoscope in coronary cardiac bypass surgery patients.

Detailed Description
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Laryngoscopy and endotracheal intubation causes significant hemodynamic response and thus presents an increased risk for patients undergoing cardiac bypass surgery. Prevention or reduction of this increment is important for hemodynamic control. In this randomized single blind study, the aim of this study is to compare the hemodynamic responses of two different laryngoscopy techniques with Glidescope and Macintosh laryngoscope in coronary cardiac bypass surgery patients. After induction with our institutional protocol for cardiac bypass surgery, hemodynamic data including heart rate, systolic and diastolic arterial pressure data will be recorded. Time for intubation, age, sex, ASA status data will also be recorded.

Official Title
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Comparison of Hemodynamic Responses to Endotracheal Intubation With Glidescope Video Laryngoscope and Macintosh Direct Laryngoscope in Patients Undergoing Coronary Artery Bypass Surgery

Conditions
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Blood Pressure

Intervention / Treatment
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* Device: Glidescope
* Device: Macintosh Laryngoscope


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: American Society of Anesthesiologists (ASA) physical Status 2-3 Patients undergoing elective cardiac bypass surgery Exclusion Criteria: Difficult intubation history Need for Rapid sequence intubation or alternative intubation method Emergency procedures Patients that have predictive factors for difficult intubation Patients with permanent pacemaker

Ages Eligible for Study
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Minimum Age: 40 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Glidescope intubation<br>This standard GlideScope (GS) technique involves a midline laryngoscopy followed by insertion of a styletted endotracheal tube, once an adequate view of the vocal cords is achieved. | Device: Glidescope<br>* This standard GlideScope (GS) technique involves a midline laryngoscopy followed by insertion of a styletted endotracheal tube, once an adequate view of the vocal cords is achieved.<br>|
| Other: Macintosh Laryngoscope<br>This standard technique involves laryngoscopy followed by insertion of a styletted endotracheal tube, once an adequate view of the vocal cords is achieved. | Device: Macintosh Laryngoscope<br>* This technique involves a laryngoscopy followed by insertion of a styletted endotracheal tube, once an adequate view of the vocal cords is achieved.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in systolic blood pressure | invasive blood pressure (mmHg) monitoring | 5 minutes; At start of laryngoscopy and after 30th seconds, 60th seconds, 90th seconds, 120th seconds, 3rd minutes, 4th minutes, 5th minutes | 
| Change in heart rate | Heart rate (beats per minute) will be measured before induction, and throughout and after laryngoscopy | 5 minutes; At start of laryngoscopy and after 30th seconds, 60th seconds, 90th seconds, 120th seconds, 3rd minutes, 4th minutes, 5th minutes | 
| Change in diastolic blood pressure | invasive blood pressure (mmHg) monitoring | 5 minutes; At start of laryngoscopy and after 30th seconds, 60th seconds, 90th seconds, 120th seconds, 3rd minutes, 4th minutes, 5th minutes | 
| Change in mean arterial pressure | invasive blood pressure (mmHg) monitoring | 5 minutes;At start of laryngoscopy and after 30th seconds, 60th seconds, 90th seconds, 120th seconds, 3rd minutes, 4th minutes, 5th minutes | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Procedure time | Total laryngoscopy and intubation time (minutes) | 10 minutes | 
| Cormack lehane laryngoscopic view will be recorded | laryngoscopic view data will be recorded according to Cormack Lehane scale (A Scale with 1-4) | 10 minutes | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Glidescope, Cardiovascular surgery, Macintosh Laryngoscope, Hemodynamic response, Anesthesia