HIV Patients Cohort

Study Overview
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Brief Summary
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The purpose of this study is to improve our knowledge concerning HIV infection, treated or not, in the current conditions of care to optimize it.

Detailed Description
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Since the arrival of highly active tritherapies, HIV infection became mainly an ambulatory chronic pathology centred on a long term care taking into account the complication of long-term treatment as well as the arisen of new problem bound to a prolonged survival and ageing. So the care is more and more in a prevention and screening approach with in particular the care of metabolic and cardiovascular complication due to antiretroviral treatment. As a reorganization of the coverage of the HIV infected people take place on the Hotel Dieu Hospital it thus seems important to double this care optimization with a clinical research side. This will be done in constituting an HIV patient cohort including a blood sample collection to contribute to the vigilance of the complication to due the infection. Our ultimate objective is to optimize the selection of the treatment. It is important to do it to be able to have, on many years duration, precise clinical information and biological sample allowing to realize later some assay and analyse the influence of some genetic markers.

Official Title
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Constitution of an Open Monocentric Cohort of HIV Infected Patients

Conditions
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Patients Affected by the HIV

Intervention / Treatment
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* Biological: OVIHD


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Aged ≥18 years old, Patients with an HIV infection patients having given their written informed consent.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: OVIHD<br>Cohort and a blood sample collection will be done with data and blood of HIV infected patients | Biological: OVIHD<br>* 7 ml of blood will be taken during a follow-up consultation and kept in a biological collection. Clinical data will be collected in a database.<br>* Other names: Blood sample;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| HIV infection | The HIV cohort will be constituted in collecting cardiovascular, neurological clinical data and medical past history (in case of women patient) | 10 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Comorbidity and complication in HIV infected patients | The HIV cohort will be constituted in collecting cardiovascular, neurological clinical data and medical past history (in case of women patient) | 10 years | 
| efficiency of the current antiretroviral therapeutic diets | The HIV cohort will be constituted in collecting cardiovascular, neurological clinical data and medical past history (in case of women patient) | 10 years | 
| Blood sample collection | To put in relation the clinical-biological relevant biological or genetic data of the follow-up a blood sample will be constituted. 7 ml will be taken to each patient and kept in a collection | 10 years | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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HIV,, infection,, cohort