A Trial Comparing Two Approaches to Weight Loss

Study Overview
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Brief Summary
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This study compared the recently developed Transforming Your Life (TYL) weight loss program to the Diabetes Prevention Program (DPP), considered the Gold Standard in behavioral weight loss treatment.

Detailed Description
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Weight loss programs evidence considerable variability in treatment outcomes and weight regain is common, signaling the need for the refinement of effective treatments. This study compared the recently developed Transforming Your Life (TYL) program to the Diabetes Prevention Program (DPP), considered the Gold Standard in behavioral weight loss treatment.

Official Title
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A Randomized Trial Comparing Two Approaches to Weight Loss

Conditions
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Overweight and Obesity

Intervention / Treatment
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* Behavioral: Transforming Your Life
* Behavioral: Diabetes Prevention Program


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria overweight/obese (body mass index>27 kg/m2) free from serious medical conditions that would complicate participation in the intervention via adherence or mobility (e.g., serious heart disease or musculoskeletal problems that would interfere with moderate exercise) had not undergone bariatric surgery able to provide medical clearance from their physician. Exclusion Criteria evidence of medical conditions that would complicate participation in the intervention via adherence or mobility (e.g., serious heart disease or musculoskeletal problems that would interfere with moderate exercise) had undergone bariatric surgery,

Ages Eligible for Study
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Minimum Age: 21 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Transforming Your Life<br>The TYL program emphasized: 1) helping participants develop and maintain healthy habits and disrupt unhealthy habits, 2) enabling participants to create a personal food and exercise environment that increases exposure to healthy eating and physical activity and encourages automatic responding to goal-related cues, and 3) facilitating participants' weight loss motivation. | Behavioral: Transforming Your Life<br>* See Transforming Your Life Arm<br>|
| Active Comparator: Diabetes Prevention program<br>The DPP recommends that participants set a weight loss reduction goal of 7% or more of their baseline body weight, reduce consumption of high fat foods as a means to reduce caloric intake, and engage in brisk walking or other moderate intensity physical activity for 150 minutes per week. Sessions include information on changing energy intake and energy output through diet and exercise, and addressing psychological, social, environmental, and motivational challenges to health behavior change. | Behavioral: Diabetes Prevention Program<br>* See Diabetes Prevention Program Arm<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Weight Loss | lbs | 10 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Caloric Intake | kilocalories | 4 months | 
| Energy expenditure | kilocalories | 4 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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weight loss treatment, Obesity