linjc16/ctgov huggingface dataset:
Assessment of HyperQ Signal for Detecting Ischemia During Dobutamine Stress ECG

Study Overview
=================
Brief Summary
-----------------
The purpose of the study is to verify the ability of the HyperQ signal to detect Dobutamine induced Ischemia. The gold standard for ischemia will be the results of Angiography if performed, or Echocardiographic imaging, which was performed during the test.

Detailed Description
-----------------
Subjects referred for Dobutamine Stress Echocardiography who will sign an Informed consent form will go through the test. High resolution ECG from 12 leads will be recorded using BSP's HyperQ system before, during and following the Echo testing. This wil be done without interfering or affecting any aspect of the normal procedure. Standard Protocol will be used with standard test termination indications. The Diagnostic stage will include analysis of the hyperQ signal, aiming to classify results as ischemic or non-ischemic. The HyperQ data will be compared to DSE results which will be used as the gold standard for this study unless Angiography results are obtained. An additional comparison evaluation will be performed to assess the advantage of the HyperQ results on the ST-changes results obtained from conventional ECG.In addition all recruited subjects will be followed for up to 12 months.During this period a phone call will be performed every 3 months to evaluate cardiac status, hospitalization and especially Angiography procedures.

Official Title
-----------------
An Assessment of the HyperQ Signal for Detecting Ischemia During Dobutamine Stress Echocardiography (DSE)

Conditions
-----------------
Myocardial Ischemia

Intervention / Treatment
-----------------
* Device: HyperQ Signal recording


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Subject referred to dobutamine stress Echocardiography Subject signed informed consent Exclusion Criteria: Subjects with implantable Pacemakers or Defibrillators Subjects with Wolff-Parkinson-White Syndrome
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Intervention/Treatment |
| --- |
|Device: HyperQ Signal recording|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| HyperQ Signal recorded during the DES Test |  |  | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| DES Outcome/ Angiography |  |  | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
HyperQ, Ischemia, dobutamine
Educating the Educator to Reduce Risk of Dance Student Injury

Study Overview
=================
Brief Summary
-----------------
A group of dance educators will attend two dance injury prevention workshops hosted by the Harkness Center for Dance Injuries (HCDI), NYU Langone Medical Center, during which participants will learn strategies to help them train their students in safe ways and impart injury prevention information through their dance classes to their students. The educators will take pre- and post-workshop tests to assess knowledge and perceptions of dance medicine. Several weeks later, participants will take a follow-up survey to assess knowledge implementation and workshop effectiveness.

Official Title
-----------------
Educating the Educator to Reduce Risk of Dance Student Injury

Conditions
-----------------
Injuries

Intervention / Treatment
-----------------
* Behavioral: Injury Prevention Workshops


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Teach dance to children in at least one private dance school Must be able to receive email and complete a survey online Must believe that students lack access to dance injury prevention resources Must teach at least one group of students that takes class from them a minimum of twice a week and must teach those students regularly in September and October, 2017. Exclusion Criteria: Under the Age of 18

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Injury Prevention Workshops<br>Subjects will attend two Injury Prevention Workshops | Behavioral: Injury Prevention Workshops<br>* Each workshop will last 90 minutes and consist of approximately 20-30 minutes of lecture, 30 minutes of movement, no more than 20 minutes for a pre-test (workshop 1) or post-test (workshop 2), and remaining time for Q&A.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Score on Injury Prevention Workshop Pre-Test and Post-Test | The test will ask subjects questions about their dance teaching background and ascertain their current knowledge of dance anatomy and injuries. | 20 Minutes | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Dance Injuries, Injury Prevention Workshops, Motor Skill Theory, Gross Motor Skills
The Factors Cause Vasospasm After Aneurysmal Subarachnoid Hemorrhage

Study Overview
=================
Brief Summary
-----------------
Extensive research has shown that the big event that leads to the initiation of vasospasm is the release of oxyhemoglobin (blood breakdown product).Depletion of NO synthase (19,20,21) was also noted after SAH.CSF is produced from choroid plexus in the ventricle. If the SAH is too dense, the blood in the subarachnoid space will not easy to be washed out.

Detailed Description
-----------------
Cerebral vasospasm remains a significant source of morbidity and mortality in patients with subarachnoid hemorrhage (SAH) after an aneurysmal rupture. Despite being a significant source of morbidity and mortality, death and disability from vasospasm have declined from approximately 35% in the early 1970's, to between 15% and 20% in the 1980's to <10% in the 1990's(1,2,3,4).Extensive research has shown that the big event that leads to the initiation of vasospasm is the release of oxyhemoglobin (blood breakdown product)(1,12,13). This mechanism appears to be a multifactorial process that involves the generation of free radicals, lipid peroxidation and activation of protein kinase C as well as phospholipase C and A2 with resultant accumulation of diacylglycerol and the release of endothelin-1(14,15,16,17,18). On the other hand, depletion of NO synthase (19,20,21) was also noted after SAH. Previous reports showed that shunting of CSF through a lumbar drain after an SAH markedly reduces the risk of clinically evident vasospasm and its sequelae, shortens hospital stay, and improves outcome. Its beneficial effects are probably mediated through the removal of spasmogens that exist in the CSF(22). In our preliminary data, we have demonstrated a case with severe vasospasm, CSF was collected both from EVD and lumbar drain. The ADMA level and amount of Nitrate was well correlate with vasospasm and the level was much higher in lumbar drain then EVD. So, we will compared the CSF from EVD and lumbar puncture to see which factor is correlate with vasospasm.

Official Title
-----------------
The Factors Cause Vasospasm After Aneurysmal Subarachnoid Hemorrhage

Conditions
-----------------
Subarachnoid Hemorrhage, Vasospasm, Intracranial

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Aneurysmal rupture with SAH Exclusion Criteria: Bleeding tendency, Large ICH with impending herniation

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
SAH, vasospasm, ADMA
Maternal and Perinatal Pregnancy Outcome in Women With Heterozygous Hemoglobinopathies

Study Overview
=================
Brief Summary
-----------------
This retrospective study aims to investigate pregnancy outcome in women with heterozygous hemoglobinopathies (regarding gestational diabetes, cholestasis and urinary tract infections) and to analyze if there are aggravated maternal and/or perinatal risks.

Official Title
-----------------
Maternal and Perinatal Pregnancy Outcome in Women With Heterozygous Hemoglobinopathies

Conditions
-----------------
Heterozygous Haemoglobinopathy

Intervention / Treatment
-----------------
* Other: pregnancy outcome


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: pregnant women with or without heterozygous hemoglobinopathy Exclusion Criteria: refusal of study participation

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Heterozygous Hemoglobinopathy<br>pregnancy outcome in women with heterozygous hemoglobinopathy | Other: pregnancy outcome<br>* descriptive statistics of variables<br>|
| No Heterozygous Hemoglobinopathy<br>pregnancy outcome in women without heterozygous hemoglobinopathy | Other: pregnancy outcome<br>* descriptive statistics of variables<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| gestational diabetes | number of women developing gestational diabetes in pregnancy | in the course of pregnancy until delivery | 
| cholestasis in pregnancy | number of women developing cholestasis in pregnancy | in the course of pregnancy until delivery | 
| urinary tract infection | number of women developing urinary tract infection | in the course of pregnancy until delivery | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
pregnancy, gestational diabetes, cholestasis in pregnancy, urinary tract infection in pregnancy
Effects of Nightshift Work and Sleep Disturbances on Erectile Function

Study Overview
=================
Brief Summary
-----------------
We aim to observe the unwanted effects of nightshift work and short term insomnia on erectile function of men aged between 25 to 60 years. We will also compare the levels of serum testosterone in the target group and compare it with the ones who don't work in hightshifts.

Official Title
-----------------
Effects of Nightshift Work and Sleep Disturbances on Erectile Function, Serum Testosterone Levels, Nocturia

Conditions
-----------------
Erectile Dysfunction, Nocturia, Short Term Insomnia, Obstructive Sleep Apnea

Intervention / Treatment
-----------------
* Diagnostic Test: IIEF-5


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Suffering from erectile dysfunction Mainly psychogenic ED Employed Exclusion Criteria: Patients with major organic causes erectile dysfunction (Radical pelvic surgery/radiation therapy, uncontrolled diabetis mellitus, uncontrolled hypertension, New York Heart Association Class 3-4 heart failure, acute coronary syndrome within 3 months, dyslipidemia) NEET(Not in employment, education, training) patients

Ages Eligible for Study
-----------------
Minimum Age: 25 Years
Maximum Age: 60 Years

Sexes Eligible for Study
-----------------
Male

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Nightshift workers<br> | Diagnostic Test: IIEF-5<br>* IIEF-15 form will be filled out by all participants<br>|
| Non-nightshift workers<br> | Diagnostic Test: IIEF-5<br>* IIEF-15 form will be filled out by all participants<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Erectile dysfunction | Decreased scores of IIEF-5 | 3-6 months |
Changes in Lab and Ultrasonography After Endoscopic Varisceal Treatment

Study Overview
=================
Brief Summary
-----------------
laboratory and ultrasongraphicc changes after endoscopical varices treatment

Official Title
-----------------
Laoboratory and Ultrasonographic Changes After Endoscopic Varisceal Treatment

Conditions
-----------------
Liver Cirrhosis

Intervention / Treatment
-----------------
* Diagnostic Test: Liver function tests (ALT,AST,ALBUMIN,BILIRUBIN,INR,PC,CBC)
* Device: biannual ultrasonography


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: patients with liver cirrhosis and portal hyprtension with esophagel varisces Exclusion Criteria: 1. Patients with heart failure or renal failure 2. patients with COPD 3. Patients with hepato cellular carcinoma and portal vein thrombosis 4. Pregnant

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 60 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| cirrhotic patients with esophagel varisces<br>Endoscopic band ligation or injection scelerotheraby will be done for all patients | Diagnostic Test: Liver function tests (ALT,AST,ALBUMIN,BILIRUBIN,INR,PC,CBC)<br>* Liver function tests will be assessed after endoscopic varisceal treatment for 6 monthes<br>Device: biannual ultrasonography<br>* portal vein diameter , portal vein velocity and flow direction, volume flow in portal vein , congetive index, spleen size.will be assessed after endoscopic varisceal treatment by using biannual ultrasonography for 6 monthes<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Changes in liver function tests | Liver function tests (ALT, AST, bilirubin,Albumin,Cbc,Prothrombin time,INR ) level (expected to be lower after endoscopic varisceal treatment (ex | 6 months | 
| Ultrasonographic changes | { portal vein diameter , portal vein velocity and flow direction, volume flow in portal vein , congetive index, spleen size.(expected to be chnged after endoscopic varisceal treatment | 6 months |
Adenomyosis: Genomic Mechanisms and Biological Response

Study Overview
=================
Brief Summary
-----------------
Examination of genomic and biologic responses to LNG-IUS in patients with adenomyosis.

Detailed Description
-----------------
Examination of genomic and biologic responses to LNG-IUS in patients with adenomyosis.

Official Title
-----------------
Adenomyosis: Genomic Mechanisms and Biological Response

Conditions
-----------------
Adenomyosis, Abnormal Uterine Bleeding

Intervention / Treatment
-----------------
* Drug: LNG-IUS


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Abnormal bleeding in the presence of Adenomyosis as demonstrated by MRI Exclusion Criteria: Other causes of abnormal bleeding such as fibroids, endometrial polyps, malignancy Presence of endometriosis

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 60 Years

Sexes Eligible for Study
-----------------
Female

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: LNG-IUS|Levnorgestrel containing IUD|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Menstrual blood loss | Pictorial blood loss assessment chart | 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Quality of Life | SF-12 | 12 months | 
| Pain | Visual analog scale | 12 months |
Evaluation of Web-Based CBT for Rape Victims

Study Overview
=================
Brief Summary
-----------------
Rape is unfortunately a common experience among women, affecting between 13 and 20%. In addition, up to 50% of all rape victims experience significant and persistent psychological distress. While cognitive-behavioral interventions have been found to be successful at alleviating distress among victims; the majority do not seek out these services, often because of feelings of stigma and self-blame. One potential method for circumventing these barriers is through online administered treatment. Thus, the current project is designed to conduct an initial evaluation of a 12 to 16-week, therapist-facilitated, multi-media, cognitive-behavioral, online intervention tailored specifically for rape victims. The effectiveness of this program at ameliorating distress among college women who have experienced rape and have current posttraumatic stress disorder (PTSD) was evaluated. Reductions in psychological distress was the primary outcome and was assessed at post-intervention and at three and six month follow-up periods. The effectiveness of the intervention was compared to a psycho-educational website.

Official Title
-----------------
Evaluation of Web-Based CBT for Rape Victims

Conditions
-----------------
PTSD

Intervention / Treatment
-----------------
* Behavioral: Online intervention
* Behavioral: Psycho-educational website


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Current rape-related PTSD Regular access to a computer English language literacy Experience of completed rape at age 14 years or older Exclusion Criteria: No current PTSD Current psychotherapy Lack of stability on psychotropic medication (< 3 months) Lack of literacy in English Current substance dependence Current elevated suicidality Severe acute distress No experience of completed rape after age 14

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 50 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Online intervention<br>Therapist-facilitated, cognitive behavioral therapy | Behavioral: Online intervention<br>* Therapist-facilitated, multimedia, cognitive-behavioral online intervention targeting rape-related PTSD<br>|
| Active Comparator: Psycho-educational website<br>Self-help, psycho-educational website | Behavioral: Psycho-educational website<br>* Psycho-educational self-help website about rape-related PTSD<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in PTSD symptoms (PTSD Symptom Scale Interview) |  | Change in PTSD symptoms from baseline to 3 months post intervention |
Full-thickness Skin vs. Synthetic Mesh in the Repair of Large Incisional Hernia

Study Overview
=================
Brief Summary
-----------------
This is a prospective randomized study to compare surgical methods for the repair of large abdominal hernia.

Detailed Description
-----------------
Patients with giant (>10 cm in diameter) abdominal wall hernia are included in a prospective randomized study comparing conventional mesh repair with the best possible method to onlay full thickness skin grafts.

Official Title
-----------------
Full-thickness Skin vs. Synthetic Mesh in the Repair of Large Incisional Hernia - a Prospective Randomized Controlled Study

Conditions
-----------------
Ventral Hernia, Postoperative Pain

Intervention / Treatment
-----------------
* Procedure: Ventral hernia repair using full thickness skin graft
* Procedure: Ventral hernia repair using mesh


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: ventral hernia > 10 centimeters, abdominal wall pain or discomfort, desire hernia repair. Exclusion Criteria: < 18 years of age, ongoing pregnancy or nursing, ongoing immunosuppressive treatment,ongoing smoking.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 90 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Hernia repair using full-thickness skin graft<br>25 patients | Procedure: Ventral hernia repair using full thickness skin graft<br>* 25 patients<br>|
| Experimental: Hernia repair using Mesh<br>25 patients | Procedure: Ventral hernia repair using mesh<br>* 25 patients<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rate of complication | Complications will be assessed over a 3 year period of regular follow-up by an objective surgeon who is unaware of which surgical method which was used. Eventual complications may include infection, bleeding, seroma and fistula formation. | 3 month, 1 year and 3 year post-operative clinical follow-up | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Ventral Hernia Pain Questionnaire (VHPQ) | All subjects will complete the VHPQ which will be used to assess their pre- and postoperative pain. | 1 year period of follow-up | 
| Abdominal wall function | All subjects will undergo testing of abdominal wall function and strength using the Biodex. | 3 year period of follow up | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Biodex, Ventral Hernia, Postoperative Pain, Ventral Hernia Pain Questionnaire, Postoperative Abdominal wall and muscle function