The Effect of Brief Bodyweight Exercise on Acute Glycemic Control in Healthy Inactive Adults

Study Overview
=================
Brief Summary
-----------------
This study will investigate whether an 11-minute bodyweight exercise session can improve short-term glycemic control. Glycemic control refers to the process of how the body regulates blood sugar. The process can be measured in different ways. This study will use a small device called a continuous glucose monitor to measure changes in glucose levels over a 24-hour period. Participants will complete two trials and the investigators will compare glycemic control after the exercise session and a control period that does not involve exercise. Food intake will be controlled such that each participant will consume the same diet in both conditions. This study will help determine whether a single session of bodyweight exercise affects glycemic control.

Detailed Description
-----------------
This study will investigate whether an 11-minute bodyweight exercise session can improve short-term glycemic control. Glycemic control will be assessed using continuous glucose monitoring for 24 hours following exercise or a control condition that does not involve exercise. The exercise and control periods will be directly supervised by a study investigator. Participants will complete two trials in a randomized, crossover manner separated by 7 days. Food intake will be controlled such that each participant will consume the same diet over the 24-hour period of measurement in both conditions. Standardized meals will be provided to participants prior and following the exercise and control conditions. This study will determine whether a single session of bodyweight exercise affects glycemic control as primarily assessed by mean 24-hour glucose.

Official Title
-----------------
The Effect of Brief Bodyweight Exercise on Acute Glycemic Control in Healthy Inactive Adults

Conditions
-----------------
Exercise

Intervention / Treatment
-----------------
* Other: Exercise


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Inactive, defined as not meeting the physical activity targets in the Canadian 24-Hour Movement Guidelines for Adults. Deemed able to safely participate in physical activity and exercise, as determined by the Canadian Society for Exercise Physiology (CSEP) Get Active Questionnaire prescreening tool. Exclusion Criteria: - Experiencing a condition that might preclude safe participation in physical activity and exercise, as determined by answering Yes to any question on Page 1 of the CSEP Get Active Questionnaire.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 35 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Bodyweight Exercise<br>A standardized 11-minute bodyweight exercise session that involves a 1-minute warm-up followed by 5, 1-minute bouts of exercise at a self-selected challenging pace, interspersed with 1-minute periods of low-intensity exercise for recovery. | Other: Exercise<br>* A single session of bodyweight exercise<br>|
| No Intervention: Non-Exercise Control<br>An 11-minute period of quiet sitting. | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 24-hour mean glucose | Mean glucose following the bodyweight exercise or control condition | 24-hour measurement period | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Glycemic variability | Variability in glucose measured following exercise or control | 24-hour measurement period | 
| Peak glucose | Peak glucose measured after each meal following exercise or control | 2-hour measurement period after each meal | 
| 2-hour postprandial mean glucose | Mean glucose measured after each meal following exercise or control | 2-hour measurement period after each meal | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Glycemic Control