linjc16/ctgov huggingface dataset:
The Prevalence of Irritable Bowel Syndrome Using Rome IV Criteria in Medical Student and The Related Factors

Study Overview
=================
Brief Summary
-----------------
A cross-sectional study of 350 medical student Universitas Indonesia from first grade until fifth grade was done during November-December 2016. This study used stratified randomized sampling. The Rome IV criteria was used for diagnosing IBS. Questionnaire-guided interview was applied to all subjects.

Detailed Description
-----------------
A cross-sectional study of 350 medical student Universitas Indonesia from first grade until fifth grade was done during November-December 2016. This study used stratified randomized sampling. The Rome IV criteria was used for diagnosing IBS. Questionnaire-guided interview was applied to all subjects. A bivariate analysis was done to know the relationship between IBS and its related factors using chi-square, unpaired t-test, and their alternatives. Multivariate analysis was done using logistic regression test

Official Title
-----------------
The Prevalence of Irritable Bowel Syndrome Using Rome IV Criteria in Medical Student and The Related Factors

Conditions
-----------------
IBS - Irritable Bowel Syndrome

Intervention / Treatment
-----------------
* Other: No intervention


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age of participant >= 15 years Volunteer to participate in study Exclusion Criteria: Red flag symptoms: febrile, vomiting, rectal bleeding, weight lost Diagnosed as having Inflammatory bowel disease Peptic ulcer drug consumption History of gastrointestinal surgery

Ages Eligible for Study
-----------------
Minimum Age: 15 Years
Maximum Age: 30 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| IBS<br>IBS group is medical student who filled Rome IV criteria for IBS | Other: No intervention<br> <br> |
| Non IBS<br>Non-IBS group is non IBS medical student based on Rome IV criteria | Other: No intervention<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Anxiety and depression | Anxiety and Depression using Hospital Anxiety Depression Scale | 1 month | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Sleep Quality | Sleep quality using Pittsburg Sleep Quality Index | 1 month | 
| Spiritual status | Spiritual status using Functional Assessment of Chronic Illness Therapy-Spiritual Wellbeing | 1 month | 
| Academic Stress | Academic stress using Student-Life Stress Inventory | 6 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
IBS, Rome IV criteria, anxiety
A Trial of Rehabilitation in Obesity Hypoventilation Syndrome (OHS)

Study Overview
=================
Brief Summary
-----------------
Obesity is an escalating problem in the UK and a proportion of these patients have a condition known as Obesity Hypoventilation Syndrome (OHS). This syndrome is associated with symptoms of breathlessness, reduction in exercise capacity, fatigue and headaches. Previous research has shown that patients with this condition tend to use healthcare services more frequently and are often at risk of other diseases such as diabetes mellitus and high blood pressure. Currently, the mainstay of treatment is noninvasive ventilation (NIV), this is a mask ventilator that patients use overnight to improve oxygen levels and remove carbon dioxide (the waste gas of breathing), however this does not fully treat the underlying problem. The research group has shown that NIV helps improve activity and contributes to weight loss in this group of patients. The aim of this research will be to investigate the effect of an exercise and nutrition programme in addition to NIV on weight loss and activity levels compared to NIV alone.

Conditions
-----------------
Obesity Hypoventilation Syndrome

Intervention / Treatment
-----------------
* Behavioral: Rehabilitation


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Diagnosis of OHS Age >18 BMI > 30 kg/m2 Chronic hypercapnia , daytime PaCO2 >6kPa FEV1/FVC ≥70% Evidence of sleep disordered breathing on overnight studies Tolerated NIV > 4hrs on 1st night during initiation of NIV Exclusion Criteria: Hypercapnic respiratory failure secondary to an identifiable cause other than OHS. Age <18 Respiratory acidosis (pH <7.35) Wheelchair/bedbound patients Cognitive impairment which would prevent the subject from complying with trial protocol Unstable coronary artery syndrome Patients postintubation or decannulation following treatment requiring acute hypercapnic respiratory failure Patients undergoing renal replacement therapy Critical peripheral vascular disease Disabling locomotor disability preventing participation in exercises involved in the rehabilitation programme Pregnancy Bariatric surgery planned within 3 months

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No Intervention: Control<br>NIV alone | |
| Experimental: Intervention<br>Rehabilitation arm | Behavioral: Rehabilitation<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| % Weight loss |  | 12 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| 6 minute walk test |  | 12 months |
Arthroscopic Guided Synovial Biopsies

Study Overview
=================
Brief Summary
-----------------
To detect accuracy of serology in diagnosis of temporomandibular joint arthritis.

Detailed Description
-----------------
According to a search of previously published studies on accuracy of serology no sensitivity or specificity data was found regarding accurate detection of arthritis through serology, hence the aim of this study is to detect accuracy of serology in diagnosis of temporomandibular joint arthritis.

Official Title
-----------------
Diagnosis of Temporomandibular Joint Arthritic Disease Using Arthroscopic Guided Synovial Biopsies

Conditions
-----------------
Temporomandibular Arthritis

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients suffering from TEMPOROMANDIBULAR JOINT ARTHRITIS. Patients should be free from any systemic disease that may affect normal healing and predictable outcome. Patients who will agree to the consent Exclusion Criteria: Patients with any systemic disease that may affect normal healing. Pregnant females. Patients with acute infection. Patients with bony ankyloses. Patients with risk of tumor dissemination.
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| accuracy of serology | To determine the sensitivity or specificity of serology in diagnosis of temporomandibular joint arthritis | 2 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Rheumatoid factor | To be measured in a blood sample with (IU/mL) unit as The normal reference range for RF is less than 15 IU/mL | 2 years | 
| C-reactive protein | To be measured in a blood sample with (mg/dL) unit where Normal CRP levels are below 3.0 mg/dL. | 2 years | 
| Anti-Cyclic Citrullinated Peptide | To be measured in a blood sample with (titre-AU) | 2 years | 
| ANA | To be measured in a blood sample with binary outcome (positive or negative) | 2 years | 
| HLA-B27 | To be measured in a blood sample with binary outcome (positive or negative) | 2 years | 
| Cellular population- type | Presence of inflammatory cells infiltrate at the synovial membrane biopsy : - type of cells | 2 years | 
| Cellular population- number of cells | Presence of inflammatory cells infiltrate at the synovial membrane biopsy: - mean number of cells | 2 years |
Pre-Approval Access to JNJ-53718678 for the Treatment of Respiratory Syncytial Virus (RSV) Infection in (a) Immunocompromised Adult and Pediatric Participants

Study Overview
=================
Brief Summary
-----------------
The purpose of this pre-approval access program is to provide treatment to immunocompromised participants with serious/life-threatening diseases or conditions (Respiratory Syncytial Virus [RSV] infection) and to collect the safety data to understand the safety profile of JNJ-53718678.

Official Title
-----------------
JNJ-53718678 RSV Pre-Approval Access_Single Patient Access (SPR) for Patients Diagnosed With RSV

Conditions
-----------------
Respiratory Syncytial Virus

Intervention / Treatment
-----------------
* Drug: JNJ-53718678


Participation Criteria
=================

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: JNJ-53718678|JNJ-53718678 will be administered as directed by treating physician.|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
According CTC to Compare the Influences of Different Methods to Remove the PDAC

Study Overview
=================
Brief Summary
-----------------
Acccording circulating tumor cells to compare the differences of different methods(routine method、no-touch principle method、laparoscopy method) to remove the ductal adenocarcinoma of pancreatic body and tail.

Official Title
-----------------
To Compare the Influences of Different Methods to Remove the Pancreatic Ductal Adenocarcinoma With the Detection of Circulating Tumor Cells

Conditions
-----------------
Carcinoma, Pancreatic Ductal, Circulating Tumor Cells

Intervention / Treatment
-----------------
* Procedure: routine surgery
* Procedure: no-touch surgery
* Procedure: laparoscopic surgery


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Ductal adenocarcinoma of pancreatic body and tail Tumor can be removed No other tumors and without liver metastases Age from 18 to 80 years old Exclusion Criteria: Neoplasms with other sites of the pancreas With other tumors of any other sites

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: routine surgery<br>In this arm the patients will be performed routine surgery to remove the tumors. And then we compare their circulating tumor cell countings in the pre and post-operation. | Procedure: routine surgery<br>* To observe if the surgeries can influence the countings of circulating tumor cells of the patients.<br>|
| Experimental: no-touch surgery<br>In this arm the patients will be performed no-touch surgery to remove the tumors. And then we compare their circulating tumor cells countings in the pre and post-operation. | Procedure: no-touch surgery<br> <br> |
| Experimental: laparoscopy surgery<br>In this arm the patients will be performed laparoscopy surgery to remove the tumors. And then we compare their circulating tumor cells countings in the pre and post-operation. | Procedure: laparoscopic surgery<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| the changes of CTCs countings between the pre and post-operation in each arm |  | Within 1 week after the surgeries are completed in any arm | 
| the changes of CTCs countings between the pre and post-operation among the arms |  | Within 2 weeks after the surgeies are all completed |
Three-dimensional Assessment of Intraventricular Dyssynchrony Using Fast Dobutamine Gated SPECT

Study Overview
=================
Brief Summary
-----------------
The prognosis of patients with heart failure has improved due to recent breakthrough in medical treatment and cardiac resynchronization devices. However, there is no paraclinical parameter to assess response to cardiac resynchronization therapy (CRT). This is a major issue since about a third of implanted patients will not be improved by CRT. CZT SPECT allows to perform myocardial perfusion imaging in less than 4 minutes and is able to study myocardial perfusion, viability, left ventricular function, but also ventricular asynchrony. Using low-dose dobutamine gated SPECT and CZT camera, we aimed to assess left ventricular dyssynchrony in viable segments in patients with heart failure eligible for CRT.

Conditions
-----------------
Heart Failure

Intervention / Treatment
-----------------
* Other: myocardial perfusion scintigraphy


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patient with heart failure on optimal medical therapy and targeted for cardiac resynchronization therapy according to current recommendations; Age over 18 years Clinically stable (without hospitalization for heart failure in the last month) Sinus rhythm Social security insurance Signed consent form Exclusion Criteria: Recent history (less than 21 days) of acute coronary syndrome or unstable angina; Recent history (less than 1 month) of acute heart failure; Right bundle branch block; Irregular heart rate; Double-chamber cardiac pacemaker Patients previously implanted with a single-chamber cardioverter-defibrillator must have at least 99 percent of unstimulated QRS. Countraindication to dobutamine therapy; Valvular heart disease, congenital heart disease, hypertrophic cardiomyopathy; Significant Ventricular arrhythmias; Hypertension (upper than 160/100 mmHg); Pregnant, breastfeeding or guardianship

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: myocardial perfusion scintigraphy<br>Low-dose dobutamine gated SPECT and CZT camera for the assessment of parameters of left ventricular dyssynchrony in heart failure patients eligible for the implantation of a cardiac resynchronization device. | Other: myocardial perfusion scintigraphy<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| measures of dyssynchrony parameters | The primary endpoint is reproducible quantitative measures of dyssynchrony parameters between two successive acquisitions basal (entropy, bandwidth, standard deviation phase histogram). | baseline |
Trial Comparing Single Versus Double Incision to Repair Distal Bicep Tendon Ruptures

Study Overview
=================
Brief Summary
-----------------
The purpose of this study to to determine whether a single incision technique or a double incision technique is more effective in the surgical treatment of distal bicep tendon ruptures. Patients will be randomized to one of the two techniques upon consenting to the study. Prior to surgery patients will have their elbow flexion, extension, pronation, and supination strength measured. Elbow Range of motion will also be measured in each of these four movements. A number of subjective questionnaires will also be administered to the patient prior to surgery. The identical objective tests and subjective questionnaires will be completed by the patient at intervals of three months, six months, one year, and two years following their surgery. Additional information from patients clinical visits may also be collected throughout the study.

Official Title
-----------------
Randomized Control Trial Comparing Single Incision Versus Double Incision Surgery to Repair Distal Bicep Tendon Ruptures

Conditions
-----------------
Distal Bicep Tendon Rupture

Intervention / Treatment
-----------------
* Procedure: Distal bicep tendon reconstruction


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Complete rupture of the Distal Bicep tendon Acute bicep tendon rupture (< 10 days since rupture) 18 years of age and older Exclusion Criteria: Partial rupture of the Distal Bicep tendon Chronic bicep tendon Ruptures (>10 days since rupture) Under 18 years of age

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Single incision repair of distal bicep tendon rupture<br>In this treatment arm patients will have a single incision technique used to repair their distal bicep tendon rupture | Procedure: Distal bicep tendon reconstruction<br>* Randomized to either a single incision technique or a double incision technique.<br>|
| Active Comparator: Double incision repair of distal bicep tendon rupture<br>In this treatment arm, patients will have a double incision technique used to repair their distal bicep tendon rupture. | Procedure: Distal bicep tendon reconstruction<br>* Randomized to either a single incision technique or a double incision technique.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Bicep, Tendon, Distal, Ruptures, Randomized, Surgery
Non-cathartic Computed Tomographic Colonography to Screen Subjects With a Family History of Colorectal Cancer

Study Overview
=================
Brief Summary
-----------------
Background: Although subjects with first-degree relatives (FDR) with a history of colorectal cancer (CRC) are at increased risk for CRC, compliance to screening colonoscopy is suboptimal. Computed tomographic colonography (CTC) has been recognized as an alternative for CRC screening in average risk subjects, but less information is available on its performance in FDRs. Aims: To prospectively assess the accuracy of CTC as a screening tool in FDRs using colonoscopy (OC) with segmental unblinding as reference standard. Methods: Consecutive patients admitted with CRC diagnosis (index case, IC) were prospectively evaluated. Following the systematic identification of ICs with inherited predispositions to CRC, ICs who agreed to contact their FDRs ≥40 years old were included. Available FDRs were invited to undergo non-cathartic CTC, with OC the following day. Sensitivity/specificity/PPV/NPV of CTC was assessed for detecting subjects with any lesion ≥6 mm, ≥10 mm, and for advanced neoplasia ≥6 mm.

Official Title
-----------------
Non-cathartic Computed Tomographic Colonography to Screen for Colorectal Neoplasia in Subjects With a Family History of Colorectal Cancer

Conditions
-----------------
Colorectal Neoplasia

Intervention / Treatment
-----------------
* Radiation: CT colonography


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Family history for CRC (first degree) Age >40 years old Exclusion Criteria: Contraindications to colonoscopy or CT colonography Pregnancy

Ages Eligible for Study
-----------------
Minimum Age: 40 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Screening
Intervention Model: Single Group Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Family Degree-relatives of pts. with CRC<br>Consecutive patients admitted with CRC diagnosis (index case, IC) were prospectively evaluated. Following the systematic identification of ICs with inherited predispositions to CRC, ICs who agreed to contact their FDRs ≥40 years old were included. Available FDRs were invited to undergo non-cathartic CTC, with OC the following day. | Radiation: CT colonography<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of patients in whom colorectal polyps and colorectal neoplasia have been detected by CT colonography, by adopting colonoscopy as gold standard, as a measure of efficacy. |  | up to 2 years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Colorectal cancer, colorectal neoplasia, CT colonography, advanced neoplasia, colonoscopy, family history
Tongue Pull Versus Jaw Thrust

Study Overview
=================
Brief Summary
-----------------
This protocol seeks to determine the efficacy and reliability of a simple maneuver, the jaw thrust maneuver, in addition to cricoid pressure, in improving visualization of airway anatomy during video laryngoscopy. Hypothesis: The grade of view of the glottis as determined by the modified Cormack and Lehane grading system in anesthetized patients will improve by performing a jaw thrust maneuver during video laryngoscopy with compared with video laryngoscopy alone. Similarly, the grade of the view during cricoid pressure will also improve with a jaw thrust maneuver.

Official Title
-----------------
Tongue Pull Versus Jaw Thrust

Conditions
-----------------
Surgery

Intervention / Treatment
-----------------
* Procedure: Jaw thrust maneuver (Intubation)


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Age > 18 Undergoing surgery and general anesthesia with endotracheal intubation Able to give informed consent Exclusion Criteria: Trauma patients or emergent cases. Patients who are unable to understand the proposed study Patients who refuse participation

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Intubation<br> | Procedure: Jaw thrust maneuver (Intubation)<br>* Visualization of Larygnoscopic anatomy during intubation<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Surgery, General Anesthesia, Intubation