Using a Thermal Imaging System to Evaluate the Wound of Port-A and the Relationship Between Thermal Images and Infection

Study Overview
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Brief Summary
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Permanently implantable venous ports (Port-A) is very important to patients receiving chemotherapy. It not only provides a reliable route to administrate intravenous drugs, and it also requires minimal care when it is not in use. However, catheter related blood stream infection(CRBSI) is one of the serious complications of Port-A. The diagnosis of CRBSI relies on limited tools, including blood culture or symptoms and signs of active infection. In the stage of CRBSI, Port-A removal is necessary and pose the risk for the patients to re-implant the Port-A. Thus, it is crucial to early detect the infection and give appropriate treatment. Among the pathogens, some pathogens are related to skin contaminants. Before systemic spreading, these pathogens may colonize or cause minor infection subcutaneously. This investigation is to utilize a non-invasive dual spectrum infrared imaging system to evaluate the Port-A wound and to detect the infection. Aim: 1. To build the database of infra-red thermal images of Port-A wound healing. 2. To investigate the thermal images of skin contamination related CRBSI and to compare with the thermal images of the CRBSI of unknown foci

Official Title
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Utilization of a Medical Dual-spectrum Infrared Thermal Imaging System to Evaluate the Wound Healing of Permanently Implantable Venous Port (Port-A) and to Investigate the Relationship Between the Thermal Images and Subcutaneous/Bloodstream Infection

Conditions
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Wound Healing Disturbance of Port-A

Intervention / Treatment
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* Device: Infrared thermal images


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: clinical requirement of chemotherapy with Port-A Exclusion Criteria: not able to maintain posture during acquiring the thermal images with other wounds over the nearby area of the Port-A wound with other severe underlying disease and too weak to mobilize

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Port-A implantation and chemotherapy<br>Patients scheduled for Port-A implantation and subsequent chemotherapy | Device: Infrared thermal images<br> <br> |
| Port-A infection<br>Patients receiving Port-A removal due to infection | Device: Infrared thermal images<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Port-A wound healing/infection status (infrared thermal images) |  | The patient will be followed once about 1 day before stitches removal of the port-A wound. | 
| Port-A wound healing/infection status (infrared thermal images) |  | The patient will be followed once about 6 to 24 hours before the first chemotherapy | 
| Port-A wound healing/infection status (infrared thermal images) |  | The patient will be followed once about 6 to 24 hours before the second chemotherapy | 
| Port-A wound healing/infection status (infrared thermal images) |  | The patient will be followed once about 1 day before Port-A removal due to infection | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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infrared thermal image, wound healing, wound infection