Patterns of Breast Cancer Management and Prognosis of Breast Cancer in China

Study Overview
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Brief Summary
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This is a multicenter, prospective, e, real-world cohort survey initiated by researchers to focus on the patterns of breast cancer management and prognosis of breast cancer in China, and to establish the multicenter, prospective breast cancer data platform. A total of 18 sites in Guangdong and Henan have cooperated to build a cooperative network unit. The sites will conduct prospective and standardized records concerning the clinical pathological features, treatment and prognosis of the early breast cancer patients who are treated in their own site each year, registering in the REDCap system.This real-world cohort study aims to provide a representative and reliable survey data of epidemiological characteristics, clinical treatment and prognosis of patients with early breast cancer in China and explore the establishment of a national multi-center breast cancer data platform model.

Official Title
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Patterns of Breast Cancer Management and Prognosis of Breast Cancer in China：a Multicenter, Prospective, Real-world Cohort Study

Conditions
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Breast Cancer

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients who are hospitalized and treated in a collaborative network unit Agree to enroll in the study and sign the informed consent form Histological diagnosis of ductal carcinoma in situ or invasive breast cancer Accept the Surgery-based surgical treatment Willing to cooperate with follow-up work Exclusion Criteria: Previously Excisional biopsy (including minimally invasive resection) of the patient's breast Previously received neoadjuvant chemotherapy Imaging or histological evidence of distant metastasis
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Breast-conserving surgery rate, | the proportion between breast-conserving surgery and breast mastectomy surgery baseline | baseline | 
| Breast-conserving surgery rate, sentinel lymph node biopsy rate | the proportion between sentinel lymph node biopsy and axillary lymph node dissection | baseline | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Epidemiological distribution of pathological stage of breast cancer | the American Joint Committee on Cancer(AJCC) cancer staging system is used to assign stage for breast cancer patients,including primary tumor stage, regional nodes stage and metastasis stage | baseline | 
| Disease free survival (DFS) | Disease free survival (DFS), which defined as the time from the diagnosis of breast cancer to the confirmed time of metastatic disease, or death due to any other cause. | 5year | 
| Overall survival (OS) | Overall survival (OS), which defined as the time from the beginning of diagnosis of breast cancer to the death with any causes. | 5year |