Surgical Management of Optic Disc Pit Maculaopathy

Study Overview
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Brief Summary
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To evaluate the anatomical and functional results of pars plana vitrectomy (PPV) combined with internal limiting membrane (ILM) peeling, endolaser photocoagulation and gas tamponade in management of optic disc pit (ODP) maculopathy.

Detailed Description
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As it is well known, optic disc pit (ODP) is a rare congenital disease which is usually associated with maculopathy (ODP-M) in the form of intraretinal and subretinal fluid accumulation at the macular area leading to visual impairment. With no definite treatment and absence of guidelines for its management, the invistigators considered their prospective, interventional case series to evaluate the anatomical and functional results of pars plana vitrectomy (PPV) combined with internal limiting membrane (ILM) peeling, endolaser photocoagulation and gas tamponade in management of optic disc pit (ODP) maculopathy.

Official Title
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Pars Plana Vitrectomy With Internal Limiting Membrane Peeling in Optic Disc Pit Maculopathy

Conditions
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Maculopathy, Optic Disc Structural Anomaly

Intervention / Treatment
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* Procedure: pars plana vitrectomy with internal limiting membrane (ILM) peeling


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients included in this study are those with ODP associated with macular detachment Exclusion Criteria: Exclusion criteria included patients unfit for general anesthesia, those with insufficient clear media to perform the surgery with ILM peeling and those with other ocular diseases that can affect central macular thickness (CMT) and the best corrected visual acuity (BCVA).

Ages Eligible for Study
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Minimum Age: 15 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Optic disc pit maculopathy<br>pars plana vitrectomy with internal limiting membrane (ILM) peeling, endolaser | Procedure: pars plana vitrectomy with internal limiting membrane (ILM) peeling<br>* pars plana vitrectomy (PPV) combined with internal limiting membrane (ILM) peeling, endolaser photocoagulation and gas tamponade in management of optic disc pit (ODP) maculopathy.<br>* Other names: Endolaser photocoagulation;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| anatomical improvement | Retinal reattachment | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Functional improvement | Visual acuity letters gain | 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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optic disc pit, retinal detachment, maculopathy