Comparison of Thoracic Paravertebral Block and Pectoral Nerve Block

Study Overview
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Brief Summary
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This study aims to compare the efficacy and safety of ultrasound-guidedPECS II block with TPVB for postoperative analgesia after VATS.

Detailed Description
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52 patients (ASA I-III) between 18 and 65 years of age, who were to undergo VATS, were randomized and divided into two groups. (26 patients in each of the PECS and TPVB groups) Thoracic paravertebral block was administered from two consecutive levels for TPVB group and a modified pectoral nerve block was performed in the PECS group. Postoperative analgesia was provided by intravenous morphine infusion using a patient-controlled analgesia device. Postoperative 24-hour total morphine consumption and duration of analgesia were the primary outcome measure. Perioperative remifentanil use, visual analog scale values during at rest and coughing, time of the first analgesic request, and additional analgesic consumption were recorded.

Official Title
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Comparison of the Results of Ultrasound-Guided Thoracic Paravertebral Block and Modified Pectoral Nerve Block for Postoperative Analgesia in Video-Assisted Thoracoscopic Surgery; A Prospective, Randomized Controlled Study

Conditions
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Thoracic Paravertebral Block, Video-assisted Thoracoscopic Surgery, Postoperative Analgesia

Intervention / Treatment
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* Procedure: paravertebral block
* Procedure: pectoral block


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Ages of 18-65 Patients who will undergo VATS ASA I-II-III patients Exclusion Criteria: Patients with ASA IV Clinically diagnosis of spinal or chest wall deformity or pathology Clinically known local anesthetic allergy Morbid obesity (body mass index>40 kg m2) Clinically diagnosis of opioid, alcohol and substance dependence Clinically diagnosis of psychiatric disease Coagulopathy

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: paravertebral group<br>The investigators performed Paravertebral block to that patient group for postoperative analgesia | Procedure: paravertebral block<br>* The investigators performed Paravertebral block to that patient group for postoperative analgesia<br>|
| Active Comparator: pectoral group<br>The investigators performed pectoral block to that patient group for postoperative analgesia | Procedure: pectoral block<br>* The investigators performed pectoral block to that patient group for postoperative analgesia<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Postoperative 24-hours total morphine consumption of patients | This will be measured only one time by pca device at the 24th hour after surgery. | 24 hours postoperatively | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Visual Analog Scale values of patients | Visual Analog Scale (VAS, 0-10; 0= no pain and 10= very severe unbearable pain) at 0-1-2-4-8-12 and 24th hours | 24 hours postoperatively | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Thoracic paravertebral block,, pectoralis block,, Video-assisted thoracoscopic surgery,, Postoperative analgesia