RETAIN: Retaining Opioid Users Entering Medication Assisted Treatment and Encouraging HCV/HIV Testing

Study Overview
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Brief Summary
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The purpose of this research study is to: assess how well individuals entering medication assisted treatment like the RETAIN e-health application as measured by their feedback on the intervention. test the impact of RETAIN on knowledge about medication-assisted treatment(MAT). assess treatment retention rates in patients completing the RETAIN intervention. test the impact of RETAIN on knowledge about HCV/HIV test the impact of RETAIN on interest in being tested for HCV/HIV

Detailed Description
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The pre-post study of RETAIN will: 1) assess the acceptability of RETAIN as measured by participant feedback about the intervention; 2) test the impact of RETAIN on knowledge about MAT, as measured by the MAT Knowledge Assessment; 3) assess MAT retention rates in patients completing the RETAIN intervention; 4) test the impact of RETAIN on knowledge about HCV/ HIV; 5) test the impact of RETAIN on interest in being tested for HCV/HIV. The acceptability of RETAIN will be assessed with a feedback form which includes questions about how helpful the intervention was (scale of 1-4), what the patient liked most and least about the intervention, and any suggestions for improving it. The average (and standard deviation) for the rated helpfulness of the intervention will be derived and the qualitative data about what they liked most and least about the intervention and suggestions for improvement will be tabulated. Pre-/post-changes in the percent of correct knowledge assessment items (i.e., about MAT and HCV/HIV) and interest in HCV/HIV testing will be analyzed using a Wilcoxon signed-rank test. The 3- and 6-month retention rates for RETAIN participants will be compared, using Fisher's exact tests, to the overall treatment retention rates at 3- and 6- months for the UC Health MAT clinics as determined by the retrospective chart review.

Official Title
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Retaining Opioid Users Entering Medication Assisted Treatment and Encouraging HCV/HIV Testing Through Active Patients Sharing Experiences and the Provision of Information About Infections -an electroNic-health Application

Conditions
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Drug Addiction, Opioid-Related Disorders, Opioid-use Disorder, Substance Use Disorders

Intervention / Treatment
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* Other: self-administered, e-health application


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: At least 18 years of age Starting MAT with methadone or suboxone or in MAT for less than 2 weeks; Exclusion Criteria: Does not sign the short form consent form

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: RETAIN<br>Participants who meet criteria will receive the RETAIN self-administered, e-health application intervention. | Other: self-administered, e-health application<br>* RETAIN is a self-administered, e-health application and includes short videos in which patients who are successfully engaged in MAT discuss what they wish they had known about MAT and its benefits when they started treatment. The intervention is designed to maximize scalability - the administration would entail handing an electronic device (e.g., tablet, laptop, etc.) to an individual who would then self-administer the intervention.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| treatment retention status after 3 months | To compare with retention rates for the overall MAT clinics and use in sample size calculations for potential follow-on trial | 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| treatment retention status after 6 months | To compare with retention rates for the overall MAT clinics and use in sample size | 6 months | 
| MAT Knowledge Assessment | To test the impact of RETAIN on knowledge about MAT | Pre and Post Tests in E-Health App Day 1 | 
| The Injection-Related Infection and Treatment Survey (I-RITS) | To test the impact of RETAIN on knowledge about HCV and HIV | Pre and Post Tests in E-Health App Day 1 | 
| Feedback on the RETAIN e-health application | feedback includes questions about how helpful the intervention was (scale of 1-4), what the patient liked most and least about the intervention, and any suggestions for improving it. | Day 1 |