Validation of myStrength's Macropersonalization Engine

Study Overview
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Brief Summary
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This is a study to validate myStrength's macropersonalization algorithm. Specifically, the study seeks to answer: Does myStrength's macropersonalization algorithm match what a clinician would offer as a diagnosis following an expert assessment? Participants will be treatment-seeking adults, ages 18 to 65, recruited from an evidence-based group psychotherapy practice. Participants will be asked to complete myStrength onboarding and a clinician-conducted initial assessment. Inter-rater reliability will be assessed to determine the consistency between myStrength and clinician in primary focus area of digital program.

Detailed Description
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Rationale and Background: Macropersonalization refers to the rules applied to a member's onboarding data that dictate their primary clinical focus and available interventions that will be recommended. Macropersonalization is a new myStrength feature that is meant to enable myStrength's ability to deliver evidence-based stepped care. Research Questions: To examine the inter-rater reliability between myStrength's macropersonalization engine and expert clinical recommendations for members' primary clinical focus. Study Design: This is a one-arm, prospective study. Population: Study participants will be adults, ages 18 to 65, seeking therapy at an evidence-based psychotherapy group practice. Data Sources: Anticipated data sources include members myStrength onboarding data, macropersonalization outputs, and clinician-administered clinical assessments. Data Analysis: A Cohen's kappa will be generated for agreement between myStrength macro-personalization primary focus area and clinician diagnosis to fulfill the primary objective. Conditional kappas based on stratification, as well as a logistic regression, will be used to determine whether demographics or treatment history are associated with concordance, and qualitative analyes will be used to describe sub-clinical or secondary focus areas associated with clinician diagnoses.

Official Title
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Validation of myStrength's Macropersonalization Engine

Conditions
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Depression, Anxiety, Trauma

Intervention / Treatment
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* Other: myStrength Macropersonalization Enginge


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Aged 18 to 85, inclusive Able to read, write, and speak in English Has access to the Internet to complete study procedures Currently engaged in therapy or has schedule an initial appointment with the Pacific Anxiety Group Exclusion Criteria: None

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Other: myStrength Macropersonalization Enginge|An onboarding process that utilizes the PHQ-9, GAD-7, and WHO-5 that leads to a user of the digital program's clinical focus and primary, secondary, and tertiary intervention recommendations.|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Inter-rater reliability on primary focus area | Inter-rater reliability between myStrength macropersonalization engine and expert clinical recommendation for an individual's primary focus | Upon completion of initial assessments by subject and clinician within 30 days of signing informed consent. | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Sleep, Digital Therapy