Vitrectomy for Branch Retinal Vein Occlusion

Study Overview
=================
Brief Summary
-----------------
To evaluate the long term outcomes of pars plana vitrectomy (PPV), with and without internal limiting membrane (ILM) peeling, in eyes with persistent macular edema secondary to branch retinal vein occlusion (BRVO). Results suggest the following hypothesis: PPV, with and without ILM peeling, appears to be beneficial in eyes with persistent macular edema due to BRVO Effectiveness is maintained long term ILM peeling does not significantly affect postoperative best corrected visual acuity (BCVA)

Official Title
-----------------
Vitrectomy for Persistent Macular Edema in Branch Retinal Vein Occlusion

Conditions
-----------------
Vitrectomy

Intervention / Treatment
-----------------
* Procedure: Vitrectomy w/o ILM peeling for macular edema with BRVO


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: duration of symptoms lasting 27 weeks Exclusion Criteria: vitreous hemorrhage severe cataract biomicroscopic vitreomacular traction and epiretinal membrane previous vitreoretinal surgery other ocular diseases that could contribute to visual loss. patients with macular branch vein occlusion patients with a history of previous grid laser photocoagulation

Ages Eligible for Study
-----------------
Minimum Age: 45 Years
Maximum Age: 86 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Surgical<br>Retrospective chart review of 70 eyes of 70 consecutive patients who underwent PPV, with and without ILM peeling, for persistent macular edema associated with BRVO | Procedure: Vitrectomy w/o ILM peeling for macular edema with BRVO<br>* Concurrent phacoemulsification and intraocular lens insertion in the capsular bag was performed, followed by PPV with separation of the posterior hyaloid from the optic disk and posterior retina with a posterior vitreous detachment was not present. Indocyanine green (ICG)-assisted peeling was performed in all consecutive patients between April 2000 and June 2003. 0.1% ICG solution was injected over the macular region. Immediately after application, the dye was washed out using a vitreous cutter. Repeated injection of ICG was not required. Triamcinolone acetonide (TA)-assisted ILM peeling was performed in all consecutive patients from July 2003 to November 2006.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Reporting of the long term outcomes of PPV, with and without ILM peeling, in eyes with persistent macular edema secondary to BRVO |  | 11 years | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Elevate the effectiveness of ILM peeling |  | 11 years | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
branch retinal vein occlusion, internal limiting membrane, macular edema, vitrectomy