Intra-muscular Botulinum Toxin A in Chronic Athletic Pubalgia

Study Overview
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Brief Summary
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Chronic athletic pubalgia is a frequent sport condition in which the effectiveness of medical treatment has not been proven. Intra-muscular injection of botulinum toxin A may have positive effects on pain in some chronic tendinitis. The investigators hypothesized that similar analgesic effect of intra-muscular botulinum toxin A may be observed in individuals with chronic AP. In the present study, the investigators aimed to describe the short-term evolution of pain and of activity limitations and quality of life, after an injection of the adductor longus with botulinum toxin A, in individuals with chronic AP, for whom medical and/or surgical treatments have failed.

Detailed Description
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The investigators included consecutive individuals with chronic athletic pubalgia for whom medical and/or surgical treatments have failed and who were treated with an intra-muscular injection of botulinum toxin A under ultrasound guidance. Participants were assessed 50 days after injection for pain using a numerical rating scale (NRS) (0, no pain, and 100, maximal pain) and for activity limitations and quality of life using the Copenhagen Hip and Groin Outcome Score (HAGOS) (0, worse outcome, and 100, most favorable outcome). Participants were also asked to self-report adverse events.

Official Title
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Intra-muscular Botulinum Toxin A in Chronic Athletic Pubalgia: a Retrospective Observational Study

Conditions
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Athletic Pubalgia

Intervention / Treatment
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* Other: Botulinum Toxin A


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: chronic AP symptom duration ≥ 3 months consistent clinical and magnetic resonance imaging findings according to the clinician failure of medical and/or surgical treatments with persistent pain and inability to return to play treatment with an intra-muscular injection of botulinum toxin A injection Exclusion Criteria: age under 18 years ongoing pregnancy or breastfeeding treatments by anticoagulants muscular disorder (e.g. polymyositis, myopathy or other neuromuscular conditions) guardianship or curatorship individuals who had received botulinum toxin type A treatment for less than one year

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Athletic pubalgia<br>Patients with chronic athletic pubalgia for whom medical and/or surgical treatments have failed and who were treated with an intra-muscular injection of botulinum toxin A injection under ultrasound guidance | Other: Botulinum Toxin A<br>* 100 UI IM in the adductor longus<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Numerical rating scale | Mean pain | 50 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| HAGOS score | Mean HAGOS total score | 50 days | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Chronic athletic pubalgia, Botulinum toxin, Groin pain, Adductor enthesopathy