Changes in Renal Artery Movement Due to Respiration Before and After Fenestrated Endovascular Repair

Study Overview
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Brief Summary
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Purpose: The purpose of this study is to evaluate the location within the renal artery of maximal angular displacement before and after fenestrated endovascular aortic repair (FEVAR) using CT with end-inspiration and end-expiration CT images before and after repair. Then, the renal artery segment with maximal angular displacement on each will be located and any changes described. Participants: There will be 30 subjects recruited from UNC Hospitals. Procedures (methods): For this study, patients will receive an additional CT sequence (end-expiration CT), which will be compared with the standard of care end-inspiration CT to calculate angular displacement and the distance from the aorta.

Detailed Description
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The investigators would like to evaluate the location within the renal artery of maximal angular displacement before and after fenestrated endovascular aortic repair (FEVAR) using CT with end-inspiration and end-expiration CT images before and after repair. The investigators would then locate the renal artery segment with maximal angular displacement on each and describe any changes. Because these patients would be getting pre and post-surgical CTs as part of standard of care, there would be no added charge to obtain the information for the study. There would be, however, minimal increased radiation exposure resulting from the extra scan being performed during end-expiration and the patients would have to consent to the slight added risk to participate.

Official Title
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Changes in Renal Artery Movement Due to Respiration Before and After Fenestrated Endovascular Repair

Conditions
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Fenestrated Endovascular Aortic Repair

Intervention / Treatment
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* Radiation: Study group


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Undergoing pre-procedural CT scan for FEVAR Exclusion Criteria: Has aortic/renal stent already Cannot receive IV contrast due to renal insufficiency or allergy Renal arteries are not patent

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Study Group<br>The purpose of this study is to evaluate the location within the renal artery of maximal angular displacement before and after fenestrated endovascular aortic repair (FEVAR) using CT with end-inspiration and end-expiration CT images before and after repair. | Radiation: Study group<br>* Patients will receive an additional CT sequence (end-expiration) at the time of their standard CT imaging before and after the repair.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in angular displacement | We will calculate the distance from the aorta and angular displacement both before and after the procedure. Then, a paired t-test will be used to compare these values to determine statistical significance. | Baseline, 6 months |