Sleep Related Breathing Disorders, Anxiety, Depression and Quality of Life Assessment in Behcet's Disease

Study Overview
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Brief Summary
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Assessment of Sleep-related breathing disorders, anxiety, depression and quality of life in Behcet's disease.

Detailed Description
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Behçet's disease (BD) was first described by Turkish dermatologist Hulusi Behçet in 1937 as a triad of recurrent oral aphthae, genital ulcerations and relapsing uveitis (1). Behçet disease (BD) is an inflammatory vasculopathy with multisystemic involvement. The clinical course usually follows a relapsing-remitting course with heterogeneous clinical manifestations (2). The complexity of signs and symptoms in BD can disturb an individual's lifestyle by causing limitation in activity. As a result, numerous psychological problems may arise. Furthermore, it was shown in some studies that in patients with BD with fatigue, there was a significant association with impaired quality of life (3). Some studies reported the sleep quality in Behcet disease is very poor, and restless legs syndrome, fatigue, depression, anxiety, and activity of Behcet disease could affect to the quality of life (4). However, to date, there have been limited studies re¬garding sleep quality, quality of life, and depression in Behcet disease patients. Extrap¬olating that Behcet disease, a kind of Vasculitis, also affects the sleep quality, it is considered a meaningful study to compare and analyze the relationship between disease activity and sleep quality, quality of life, and depression in Egyptian population of Behcet disease patients.

Official Title
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Sleep Related Breathing Disorders, Anxiety, Depression and Quality of Life Assessment in Behcet's Disease

Conditions
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Behcet Syndrome

Intervention / Treatment
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* Diagnostic Test: sleep study


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Clinical examination and assessment of Behçet's disease activity (International Criteria for Behçet's disease - point score system: scoring ⩾4 indicates Behçet's disease). Exclusion Criteria: Patients who refuse to participate in the study.

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Diagnostic Test: sleep study|Assessment of sleep disorders using either sleep study or a set of sleep questionnaires (Epworth sleepiness scale, SF36, Pittsburgh sleep quality index)|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| prevalence and type of sleeping disorders among Behcet's disease population | prevalence and type of sleeping disorders among Behcet's disease population | 4 months | 
| presence and degree of anxiety, depression and fatigue in those patients | presence and degree of anxiety, depression and fatigue in those patients | 4 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Behcet Syndrome, Obstructive Sleep Apnea, Anxiety Neuroses