Polyethylene Bag: a Way of Preventing Hypothermia During Central Venous Catheter Placement in Preterm Neonates?

Study Overview
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Brief Summary
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Particular attention is paid to thermal management of preterm neonates in neonatal intensive care units because of the major risk of morbidity associated with hypothermia. Percutaneous central venous catheter placement is essential to ensure adequate caloric intake and intravenous administration of treatments, but this procedure can cause major body temperature variations, responsible for complications in these neonates, as convection incubator function is impaired during opening of the incubator, which can be prolonged (30 minutes to 2 hours) depending on the technical difficulties encountered during catheter placement. In parallel, the use of a polyethylene bag or sheet in the delivery room and for neonatal transport is now clearly defined and ensures stability or even a considerable temperature gain during transfer immediately after birth. In the light of several clinical cases, the use of a polyethylene bag during central venous catheter placement appears to be effective to prevent body temperature loss in preterm neonates. No data are currently available concerning the value of this method of prevention of hypothermia during this type of procedure. Preliminary studies conducted by our team on a dummy suggest that a polyethylene bag or sheet could be useful during this procedure by significantly reducing heat loss caused by convection and evaporation. However, compensation phenomena such as generalized vasoconstriction to cold in preterm infants are very poorly described, but can induce a functional conflict between mechanisms ensuring maintenance of homeostasis and those involved in maintenance of blood pressure.

Official Title
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Polyethylene Bag: a Way of Preventing Hypothermia During Central Venous Catheter Placement in Preterm Neonates?

Conditions
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Preterm Neonates

Intervention / Treatment
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* Device: polyethylene bag


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: premature Newborn child = 32 weeks of gestational age 7 days of life Normothermic (core temperature between 36.5 and 37.5 ° C) Stable on a hemodynamically manner Need the installation of a central catheter KTEC Exclusion Criteria: Parental Refusal hypothermia (temperature < 36.5 ° C) Hyperthermia (temperature > 37.5 ° C) heart disease and malformation syndromes life-threatening Hemodynamic instability ( catecholamine vasoconstrictor and vasodilator ) Breakdown by oscillation

Ages Eligible for Study
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Maximum Age: 7 Days

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| with the use of a polyethylene bag<br> | Device: polyethylene bag<br>* The infant will be wrapped in a polyethylene bag 15 min before starting central venous catheter placement<br>|
| without the use of a polyethylene bag<br> | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Temperature | difference between the prehepatic temperature at the beginning of catheter placement and the lowest temperature observed during the procedure | 1 hour | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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hypothermia, central venous catheter placement, Polyethylene bag