Emergency Pancreaticoduodenectomy: a Non-trauma Center Case Series

Study Overview
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Brief Summary
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Pancreaticoduodenectomy is a challenging procedure itself, being even more complex and demanding in emergency settings. Only a few cases of emergency pancreaticoduodenectomy (EPD) are reported in medical literature, usually performed for complex pancreaticoduodenal lesions. EPD has first been mentioned in trauma settings, even fewer cases being reported for non-traumatic indications. The investigators intend to present our experience with this intervention, in a non-trauma surgical centre. Our study is a prospective consecutive case series, that included patients that underwent emergency pancreaticoduodenectomy from January 2014 to May 2021. Data was collected from the electronic system database. The investigators collected data regarding the demographic characteristics of the patients, their medical history, preoperative and postoperative investigations (including blood work and imagistic investigations), surgery related information and postoperative evolution.

Official Title
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Emergency Pancreaticoduodenectomy: a Non-trauma Center Case Series

Conditions
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Emergencies, Pancreas Disease

Intervention / Treatment
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* Procedure: emergency pancreaticoduodenectomy


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Emergency pancreaticoduodenectomy performed Exclusion Criteria: Elective surgery Insufficient data

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Intervention/Treatment |
| --- |
|Procedure: emergency pancreaticoduodenectomy|Emergency pancreaticoduodenectomy (EPD) is a complex surgical procedure, that can be performed for complex pancreaticoduodenal injuries, that cannot be controlled through less invasive procedures. EPD can be performed either as a classical Whipple procedure, or as a pylorus-preserving procedure. A one stage procedure implies the reconstruction step being done in the same surgical intervention, while a two step procedure implies the reconstruction being done in a later stage, through a second surgical intervention.|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Intraoperative blood loss | ml of blood | The length of the surgical intervention (an average of 3 hours) | 
| Operative time | minutes of operating time | The length of the surgical intervention (an average of 3 hours) | 
| In-hospital Morbidity |  | Up to 90 days. Through study completion, during the hospital admission period | 
| In-hospital Mortality |  | Up to 90 days. Through study completion, during the hospital admission period | 
| Long-term evolution | It will be measured the overall survival time, number of readmissions and number of reinterventions | The date of the last follow-up information was August 2021 |