TLIP Block Versus Modified TLIP Block for Posterior Decompression and Stabilization Surgery

Study Overview
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Brief Summary
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This study aimed to compare the analgesia effectivity of TLIP and modified TLIP block in Posterior Lumbar Decompression and Stabilization Surgery Perioperatively.

Detailed Description
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This study aimed to compare the analgesia effectivity of TLIP and modified TLIP block in Posterior Lumbar Decompression and Stabilization Surgery. Intraoperatively, total fentanyl consumption, hemodynamic, and mean qNox Score was recorded. And Postoperatively, the patient was given the PCA, and total morphine consumption was assessed.

Official Title
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Perioperative Analgesia Efectivity of Thoracolumbar Interfascial Plane Block Compared Modified Thoracolumbar Interfascial Plane Block in Posterior Lumbal Decompression and Stabilization: Research in Intraoperative Hemodynamic and qNox and Total Morfin Comsumption and Postoperative IL-6 Concentration

Conditions
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Analgesia, Surgical Procedure, Unspecified

Intervention / Treatment
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* Procedure: Thoracolumbar Interfascial Plane block
* Procedure: Modified Thorcolumbar Interfascial Plane block


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients undergo thoracolumbar Decompression and Stabilization Surgery Age between 18-65 years old BMI >18,5 kg.m2, and BMI< 30 kg/m2 ASA 1-3 No contraindications for the patients to do the Block, and the patients agree and signed the informed consent before the procedure was done Exclusion Criteria: Obese patient, with BMI>30 kg.m2 Alergic to local anesthetics Underweight patient with BMI <18,5 kg/m2

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Thoracolumbar Interfascial Plane block<br>Patient will receive Thoracolumbar Interfascial Plane block | Procedure: Thoracolumbar Interfascial Plane block<br>* Interfascial block done by injection between m. multifidus and m. longissimus<br>Procedure: Modified Thorcolumbar Interfascial Plane block<br>* Injection of local anesthetics between m. longissimus and m. illiocostalis<br>|
| Experimental: Modified Thoracolumbar Interfascial Plane block<br>Patient will receive modified Thoracolumbar Interfascial Plane Block | Procedure: Thoracolumbar Interfascial Plane block<br>* Interfascial block done by injection between m. multifidus and m. longissimus<br>Procedure: Modified Thorcolumbar Interfascial Plane block<br>* Injection of local anesthetics between m. longissimus and m. illiocostalis<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Hemodynamic | Stability of Hemodynamics that needs the fentanyl addition | approximately 15 minutes within surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| qNox Score | qNox score were taken before induction of anesthesia, 15, 30 and 45 minutes after the block done. the mean of 15,30 and 45 minutes qNox score was assesed | before induction of anesthesia, 15, 30, 45 minutes after the block was done. | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Thoracolumbal Interfascial Plane Block, Erector Spinae Plane Block, opioid consumption, numerical rating scale, Interleukin 10, Interleukin 6