Individual Dietary Counseling Based on Taste-tests in Patients With Hematological Cancer in Cytostatic Therapy

Study Overview
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Brief Summary
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The purpose of the study is to investigate whether a simple taste-test will increase the intake of energy as part of the individual dietary counseling.

Detailed Description
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The investigators will investigate the tastes (umami, bitter, salty, sweet and sour) that the patients prefers in order to increase the energy intake and reduce the risk of weight loss and loss of fat-free mass for patients with hematological cancer. The study will be conducted as a single blinded randomized controlled trial. 40 patients will be recruited, and will be divided into two groups; the intervention group and the control group. The patients will not know which group they belong to.

Official Title
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Individuel diætvejledning på Baggrund af Smagstest Hos Patienter Med hæmatologisk Cancer i Cytostatisk Behandling

Conditions
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Hematological Malignancy

Intervention / Treatment
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* Dietary Supplement: Taste-test
* Other: Standard care


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 18 years or older Able to understand the Participant Information paper Diagnosed with hematological cancer Must be undergoing chemotherapy (at least one treatment during the study) Outpatient Be able to take pictures of meals (and send to the sub-investigators) Be able to speak and read the danish language Exclusion Criteria: Pacemaker
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Intervention group<br>The patients will receive a individual dietary counseling based on the taste-test | Dietary Supplement: Taste-test<br>* Patients will receive a dietary counseling based on a simple taste-test<br>* Other names: Dietary counseling;|
| Placebo Comparator: Standard dietary counseling<br>The patients will receive a individual standard dietary counseling not based on the taste-test | Other: Standard care<br>* Patients will receive a dietary counseling based on a standard dietary counseling for the patient group<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Consumption of energy as a percentage of estimated need | difference - before and after intervention | 6 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Fat-free-mass and fat-mass in percent (bioimpedance measurement) | difference - before and after intervention | 6 weeks | 
| Satisfaction (measured with EROTC QLQ-C30 version 3.0) | difference - before and after intervention. Higher scores means worse outcome. Lower scores means better outcomes. | 6 weeks | 
| Hand-grip-strength (measured with a dynamometer) | difference - before and after intervention | 6 weeks | 
| Body weight | difference - before and after intervention | 6 weeks | 
| Protein intake | difference - before and after intervention | 6 weeks | 
| Burning/pain in the mouth (measured on a scale) | difference - before and after intervention measured with Likert scale (1 to 5). Higher scores means a worse outcome. Lower scores means better outcomes. | 6 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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cancer, hematological, malignancy