Effects of WBV Associated With IMT on Functionality

Study Overview
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Brief Summary
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The pre-frail elderly are a population more vulnerable to diminished functionality and future disabilities. Thus, interventions focused on the prevention of sarcopenia are indicated to prevent dysfunction in this population. This study aims to evaluate the effects of whole body vibration training associated with inspiratory muscle training on functional outcomes, balance and muscle metabolism in pre-frail elderly women.

Official Title
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Effects of Whole Body Vibration Associated With the Inspiratory Muscle Training Program on Functional Capacity, Balance and Muscle Metabolism

Conditions
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Frail Elderly Syndrome

Intervention / Treatment
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* Other: WBV + IMT
* Other: WBV + IMTsham
* Other: WBVsham + IMTsham


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: To able to walk without assistance Good understanding to carry out the proposed tests, evaluated through the Mini Mental State Examination (MMSE). Exclusion Criteria: Contraindication or difficulty to perform evaluation procedures Users of medications that interfere with the cardiovascular and / or muscular system Smokers Neuromuscular or degenerative diseases Pulmonary comorbidities Heart diseases and labyrinthitis

Ages Eligible for Study
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Minimum Age: 60 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: WBV + IMT<br>Whole body vibration training associated with respiratory muscle training (WBV + IMT) | Other: WBV + IMT<br>* The whole body vibration training will be performed through a vibrating platform with three axes and vibration frequency set at 35 Hz. The amplitude used will be 02 to 04 mm.The inspiratory muscle training will be performed through a device that provides inspiratory resistance.<br>|
| Active Comparator: WBV + IMTsham<br>Whole body vibration training associated with respiratory muscle training sham (WBV + IMTsham) | Other: WBV + IMTsham<br>* The whole body vibration training will be performed through a vibrating platform with three axes and vibration frequency set at 35 Hz. The amplitude used will be 02 to 04 mm.The inspiratory muscle training sham will be performed through a device without inspiratory resistance.<br>|
| Sham Comparator: WBVsham + IMTsham<br>Whole body vibration training sham associated with respiratory muscle training sham (WBVsham + IMTsham) | Other: WBVsham + IMTsham<br>* Whole body vibration training will be performed through a vibrating platform coupled to a device that generates non-therapeutic low frequency vibration. The simulation of inspiratory muscle training will be performed through a device with no inspiratory resistance.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Walking Distance | The walking distance will be assessed through the six-minute walk test. | Change from Baseline walking distance at 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Balance | Static balance and dynamic balance will be evaluated through the Tinetti test | Change from Baseline balance at 3 months | 
| Functionality | It will be evaluated through the Timed Up and Go (TUG) test. | Change from Baseline functionality at 3 months | 
| Hand grip strength | The strength of the dominant hand will be evaluated by dynamometry. | Change from Baseline hand grip strength at 3 months | 
| Muscle Metabolism | It will be assessed through the blood lactate and glucose rate after moderate physical activity. | Change from Baseline muscle metabolism at 3 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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aging, functional capacity, muscle metabolism