Evaluation of Respiratory Parameters and Functional Capacity in Coronary Artery Patients

Study Overview
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Brief Summary
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The purpose of this study is to evaluate respiratory parameters and functional capacity in coronary artery patients.

Detailed Description
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Decreased pulmonary function as measured by forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), or peak expiratory flow (PEF) has been associated with an increased risk of cardiovascular mortality and morbidity. A low MIP value may generally indicate weak muscle strength and therefore be an indicator of general poor health. Respiratory muscle weakness and decreased respiratory muscle endurance affect exercise tolerance in individuals with chronic disease, including cardiovascular disease. Studies have supported the association of grip strength with frailty, physical activity, diabetes, functional limitation, nutritional status, metabolic syndrome, and mortality. The study will evaluate respiratory parameters and functional capacity in coronary artery patients.

Official Title
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Evaluation of Respiratory Parameters and Functional Capacity in Coronary Artery Patients

Conditions
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Coronary Artery Disease

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients with coronary artery disease Volunteering to participate in the research Exclusion Criteria: Having a musculoskeletal problem Having unstable cardiac disease Having chronic heart failure (NYHA III-IV) A history of acute coronary syndrome or surgical revascularization less than 3 months ago Having arrhythmia Having the last stage of kidney disease Having active myocarditis or pericarditis

Ages Eligible for Study
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Minimum Age: 41 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Control Group<br>Individuals without cardiac and pulmonary disease | |
| Study Group<br>Individuals with coronary artery disease | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Six-minute-step test | The number of steps the participant climbed up and down is recorded. | Day 1 | 
| Respiratory muscle strength | Respiratory muscle strength will be evaluated using a mouth pressure device. | Day 1 | 
| Respiratory muscle endurance | Respiratory muscle endurance will be evaluated using a constant load test. | Day 1 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pulmonary functions | Forced vital capacity (FVC), Forced expiratory volume at one second (FEV1), Peak expiratory flow (PEF) assessment via spirometry. | Day 1 | 
| Hand grip strength | Hand grip strength is evaluated by a hand dynamometer. | Day 1 | 
| Functional Capasity | The functional capacity is assessed with The Duke Activity Status Index (DASI). | Day 1 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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respiratory function test, physical functional performance, coronary artery disease