Assessment of Ovarian Reserve Tests in Unexplained Infertile Women

Study Overview
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Brief Summary
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IN UNEXPLAINED INFERTILITY IN WOMEN ,OVARY RESERVE IS BORDERLINE IF ASSESSED USING HIGH-SENSITIVE TESTS.

Detailed Description
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IN UNEXPLAINED INFERTILITY OVARIAN RESERVE TESTS WERE ASSESSED. IN THIS STUDY, A COMPARISON IS DONE BETWEEN 35 WOMEN WITH UNEXPLAINED FERTILITY(THE PATIENT) AND 35 WOMEN WHO DON'T HAVE ANY FERTILITY PROBLEMS AND HAVE AT LEAST A CHILD (THE CONTROL GROUP). THE STUDY PARTICIPANTS SHOULD HAVE THE FOLLOWING CRITERIA Inclusion Criteria: LESS THAN 35 YEARS OLD, MARRIED WOMEN SHOULD HAVE REGULAR MENSES SHOULD HAVE AT LEAST A YEAR OF UNPROTECTED SEX. THE HUSBAND'S SPERMOGRAM SHOULD HAVE NO ABNORMALITIES THE SUBJECT SHOULD HAVE A NORMAL HYSTEROSALPHINGOGRAPHY Exclusion Criteria: HAVING ANY SYSTEMIC DISEASE. LONG HISTORY OF ANY DRUG USAGE. FOR THE CONTROL GROUP Inclusion Criteria: LESS THAN 35 YEARS OLD, MARRIED WOMEN SHOULD HAVE REGULAR MENSES AT LEAST HAVE A CHILD THE HUSBAND'S SPERMOGRAM SHOULD HAVE NO ABNORMALITIES THE SUBJECT SHOULD HAVE A NORMAL HYSTEROSALPHINGOGRAPHY Exclusion Criteria: HAVING ANY SYSTEMIC DISEASE. LONG HISTORY OF ANY DRUG USAGE. THE STUDY INCLUDES THE FOLLOWING TESTS BEING DONE ON THE PATIENTS: THE FOLLOWING HORMONES' LEVELS WERE STUDIED:AMH (ANTI-MULLERIAN HORMONE),FSH (FOLLICULAR STIMULATING HORMONE) , E2 (ESTRADIOL) AND INHIBIN B.THE FORMER THREE HORMONE LEVELS SHOULD BE ASSESSED ON THE THIRD DAY OF MENSES IN THE STUDY,TRANSVAGINAL ULTRASONOGRAPHIC OVARIAN VOLUME ,OVARIAN ANTRAL FOLLICULE NUMBER,OVARIAN STROMAL BLOODFLOW AND OVARIAN ARTERIAL RESISTANCE WAS MEASURED USING DOPPLER ULTRASONOGRAM.

Official Title
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Assessment of Ovarian Reserve Tests in Unexplained Infertile Women

Conditions
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Infertility, Infertility, Female

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: LESS THAN 35 YEARS OLD, MARRIED WOMEN SHOULD HAVE REGULAR MENSES SHOULD HAVE AT LEAST A YEAR OF UNPROTECTED SEX. Exclusion Criteria: HAVING ANY SYSTEMIC DISEASE. LONG HISTORY OF ANY DRUG USAGE.

Ages Eligible for Study
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Minimum Age: 21 Years
Maximum Age: 35 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| FERTILE GROUP<br>WOMEN HAVE NO INFERTILITY PROBLEMS AND HAVE AT LEAST ONE CHILD | |
| UNEXPLAINED INFERTILE GROUP<br>WOMEN WITH INFERTILITY PROBLEMS,NO HISTORY OF PREGNANCY AND HAVE NO CHILDREN | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| LEVELS OF OVARIAN RESERVE MARKERS IN THE SERUM | AMH (ANTI-MULLERIAN HORMONE),FSH (FOLLICLE STIMULATING HORMONE),E2 (ESTRADIOL)AND INHIBIN -B LEVELS WILL BE TESTED | ONE DAY | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| ULTRASONOGRAPHIC ASSESSMENT OF OVARIAN RESERVE MARKERS | OVARIAN ANTRAL FOLLICULE COUNT ,OVARIAN VOLUME MEASUREMENT,OVARIAN DOPPLER -ULTRASONOGRAPHIC ASSESSMENT | ONE DAY |