Effect of Strength and Conditioning Training on Functional Performance in Children With Chronic Kidney Disease

Study Overview
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Brief Summary
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Despite the benefits of physical rehabilitation among adults and children with chronic illness, they avoid to engage in different physical activities especially pediatric population. Most of the children with Chronic kidney disease receive their medical treatment and follow-up with no change of their functional performance. We still lack the evidence of plyometric exercises in pediatric population with Chronic kidney disease . Therefore, the primary aim of this study is to explore the effects of strength and conditioning training in the form of plyometric exercises on balance and muscle strength in children with Chronic kidney disease .

Official Title
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Effect of Strength and Conditioning Training on Functional Performance in Children With Chronic Kidney Disease

Conditions
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Chronic Kidney Diseases

Intervention / Treatment
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* Other: medical treatment
* Other: plyometric exercise


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age will be ranged from 6-10 years. Both genders were included. Can follow instructions. Medically stable sedentary children with CKD, GFR (stage 2 (mild) eGFR of 60-89 ml/min per 1.73 m2, stage 3 (moderate) eGFR 30-59 ml/min per 1.73 m2) stage 4 (severe) eGFR of 15-29 ml/min per 1.73 m2. Did not yet require renal replacement therapy (non-dialysis). Exclusion Criteria: Recent myocardial infarction, uncontrolled hypertension, unstable angina, symptomatic left ventricular fibrillation. Severe uncontrolled diabetes, Neurological or cognitive disorders Peripheral vascular disease.

Ages Eligible for Study
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Minimum Age: 6 Years
Maximum Age: 6 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: control group<br> | Other: medical treatment<br>* traditional medical treatment and regular follow-up<br>|
| Experimental: Experimental group<br> | Other: medical treatment<br>* traditional medical treatment and regular follow-up<br>Other: plyometric exercise<br>* Each session starts with a 5-minute warm-up of flexibility exercises (active range motion and stretching exercises).The main plyometric exercise set will be applied for 20-30 minutes and consisted of 10 exercises directed at the lower body that gradually progress by increasing the set/repetition number in two exercise blocks, each continue for 1 month .The cool down period is 5 minutes and includes walking at self-preferred speed and static stretches of the major muscle groups.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Balance | The Human Assessment Computer (HUMAC), a computerized dynamic posturography (commuter sports medicine, Inc., Stoughton, MA),will be used in the current study. | after 2 months | 
| muscle strength | The Laffayette manual muscle testing (model 01163 USA) is used for objectively quantifying muscle strength including hip flexors and abductors; knee flexors and extensors | after 2 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Chronic Kidney Diseases, plyometric exercises, muscle strength, balance