The Effect of Single Umbilical Artery Caused by Umbilical Artery Embolism on Pregnancy Outcome

Study Overview
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Brief Summary
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To investigate the relationship between single umbilical artery caused by umbilical artery embolism and pregnancy outcome , and to provide evidence-based evidence for peripartum health care of pregnant women with umbilical artery embolism.

Official Title
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The Effect of Single Umbilical Artery Caused by Umbilical Artery Embolism on Pregnancy Outcome

Conditions
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Umbilical Artery Embolism,Single Umbilical Artery,Pregnancy Outcome

Intervention / Treatment
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* Other: collect information about all participants


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 18   34years old B-ultrasound first showed double umbilical artery, then single umbilical artery or pregnant women with umbilical artery embolism supported by intrapartum and postpartum pathology. B-ultrasound of prenatal examination showed a single umbilical artery, and prenatal and postpartum pathology showed pregnant women with a single umbilical artery. Exclusion Criteria: The fetus has extracardiac malformation and aneuploid deformity

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 34 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| pregnant women with Single Umbilical Artery<br>pregnant women with Single Umbilical Artery | Other: collect information about all participants<br>* collect information On age,pregnancy history,Height, weight,Gestational weeks of umbilical artery embolism,Gestational week of delivery, mode of delivery, newborn birth weight, birth height, Apgar score, umbilical cord length, umbilical cord placental insertion point, placental weight, pregnancy complications, coagulation function,after obtaining the consent of all participants.<br>|
| pregnant women with Umbilical Artery Embolism<br>pregnant women with Umbilical Artery Embolism | Other: collect information about all participants<br>* collect information On age,pregnancy history,Height, weight,Gestational weeks of umbilical artery embolism,Gestational week of delivery, mode of delivery, newborn birth weight, birth height, Apgar score, umbilical cord length, umbilical cord placental insertion point, placental weight, pregnancy complications, coagulation function,after obtaining the consent of all participants.<br>|
| Normal pregnant women<br>Normal pregnant women without pregnancy complications | Other: collect information about all participants<br>* collect information On age,pregnancy history,Height, weight,Gestational weeks of umbilical artery embolism,Gestational week of delivery, mode of delivery, newborn birth weight, birth height, Apgar score, umbilical cord length, umbilical cord placental insertion point, placental weight, pregnancy complications, coagulation function,after obtaining the consent of all participants.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Gestational week of delivery | The gestational age of delivery is determined according to the last menstruation and ultrasonic diagnosis. | 32 weeks to 40 weeks gestation | 
| mode of delivery | The mode of delivery including vaginal delivery and cesarean section, is determined by the exact condition of pregnancy. | 32 weeks to 40 weeks gestation | 
| newborn birth weight | Newborn weight is measured immediately after birth. | 32 weeks to 40 weeks gestation | 
| birth height | Birth height is measured immediately after birth. | 32 weeks to 40 weeks gestation | 
| Apgar score | Apgar score is assessed at 1 min and 5 minute after birth. | 32 weeks to 40 weeks gestation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| coagulation function | Coagulation function including prothrombin time and activated partial thromboplastin time is measured just before delivery. | 32 weeks to 40 weeks gestation | 
| placental weight | Placental weight is measured after delivery of the placenta. | 32 weeks to 40 weeks gestation | 
| umbilical cord placental insertion point | The placenta is observed after delivery to determine the insertion point of the umbilical cord in placenta. | 32 weeks to 40 weeks gestation | 
| umbilical cord length | Umbilical cord length is measured after delivery of the neonate. | 32 weeks to 40 weeks gestation |