Patient Function/Fitness and Psychosocial Health in Improving Health-Related Quality of Life in Patients With Stage I-IV Non-Small Cell Lung Cancer

Study Overview
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Brief Summary
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This pilot trial studies patient function/fitness and psychosocial health in improving health-related quality of life and decreasing treatment-related toxicity in patients with stage I-IV non-small cell lung cancer. Studying function/fitness and psychosocial health may help doctors improve conventional therapy in patients with non-small cell lung cancer.

Detailed Description
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PRIMARY OBJECTIVES: I. To determine the correlation of patient-reported health-related quality of life (HRQOL) outcomes with clinical/treatment variables as well as a panel of both function/fitness and psychosocial health assessments in non-small cell lung cancer (NSCLC). SECONDARY OBJECTIVES: I. To investigate the panel of function/fitness and psychosocial health assessments with patient's smoking history/status as a predictor for treatment related toxicity. TERTIARY OBJECTIVES: I. The documentation of the NSCLC lung population from this prospective combined with others. OUTLINE: Patients scheduled for surgery, radiation therapy, or chemotherapy complete the European Organization for Research and Treatment of Cancer (EORTC) quality of life questionnaire (QLQ)-core 30 (C30) and QLQ-Lung Cancer 13 (LC13) in addition to psychosocial health and smoking status questions from baseline up to 2 weeks prior to the start of treatment, 5-6 weeks after treatment begins, and 5-6 months from the start of treatment. During the same time points, patients also undergo function/fitness assessments including standard health measurements, short physical performance battery (SPPB), 6 minute walk test (6MWT), and a grip strength test. After completion of study treatment, patients are followed up every 3-6 months.

Official Title
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A Pilot Study Investigating Patient Function/Fitness and Psychosocial Health in Patients With Non-Small Cell Lung Cancer

Conditions
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Smoking, Lung Neoplasms

Intervention / Treatment
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* Other: Integrated Fitness Assessment
* Procedure: Psychosocial Assessment and Care
* Procedure: Quality-of-Life Assessment


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Newly diagnosed lung cancer Exclusion Criteria: Previous or active lung cancer treatment at the time of registration

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Ancillary-Correlative (HRQOL, fitness and psychosocial health)<br>Patients scheduled for surgery, radiation therapy, or chemotherapy complete the European Organization for Research and Treatment of Cancer (EORTC) quality of life questionnaire (QLQ)-core 30 (C30) and QLQ-Lung Cancer 13 (LC13) in addition to psychosocial health and smoking status questions from baseline up to 2 weeks prior to the start of treatment, 5-6 weeks after treatment begins, and 5-6 months from the start of treatment. During the same time points, patients also undergo function/fitness assessments including standard health measurements, short physical performance battery (SPPB), 6 minute walk test (6MWT), and a grip strength test. | Other: Integrated Fitness Assessment<br>* Undergo function/fitness assessment<br>Procedure: Psychosocial Assessment and Care<br>* Undergo psychosocial health assessments<br>* Other names: Psychosocial Support;Procedure: Quality-of-Life Assessment<br>* Complete EORTC QLQ-C30 and QLQ-LC13 questionnaires<br>* Other names: Quality of Life Assessment;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Patient function/fitness | Assessed by standard health measurements. | Up to 6 months | 
| Patient well-being | Assessed by questionnaires. | Up to 6 months | 
| Patient function/fitness | Assessed by performance-based measures. | Up to 6 months | 
| Patient well-being | Assessed by psychosocial health questions. | Up to 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Stage I, Stage II, Stage IIIA, Stage IIIB, Stage IV, Non-Small Cell