Effect Of Methylphenidate On Balance In Children With Attention Deficit Hyperactivity Disorder

Study Overview
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Brief Summary
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Attention Deficit Hyperactivity Disorder is a neurodevelopmental disorder that may have poor motor coordination and balance control. The effect of Methylphenidate treatment on balance and fall risk is still unclear. This study aimed to evaluate the effect of methylphenidate (MPH) treatment on balance, fall risk, and sensorimotor integration in children with Attention Deficit Hyperactivity Disorder (ADHD).

Detailed Description
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Children who were diagnosed with ADHD for the first time were classified in the ADHD group (n=33), children with ADHD who were treated with MPH for a minimum of 3 months were classified in the treatment group (n=32), and typically developing children were classified in the third-the control group (n=20) in this observational cross-sectional study. Fall risk, static postural balance and sensorimotor integration were assessed using the Biodex Balance System.Postural stability tests, including overall stability index (OSI), anterior-posterior stability index (APSI), and medial-lateral stability index (MLSI), were used to evaluate postural control. The Modified Clinical Test of Sensory Interaction in Balance (m-CTSIB) testing protocol was used to evaluate sensory integration capabilities and balance. Fall risk was evaluated by biodex balance system.

Official Title
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Effect Of Methylphenidate On Static Balance And Fall Risk In Children With Attention Deficit Hyperactivity Disorder: Cross-Sectional Study

Conditions
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Attention Deficit Hyperactivity Disorder

Intervention / Treatment
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* Device: Fall risk


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: -children who were diagnosed with ADHD for the first time according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V, American Psychiatric Association, 2013) Exclusion Criteria: neurological disorders psychiatric disorders musculoskeletal disorders cardiopulmonary diseases visual impairments developmental coordination disorders that could affect balance

Ages Eligible for Study
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Minimum Age: 8 Years
Maximum Age: 12 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| ADHD group<br>Children who were diagnosed with ADHD for the first time were classified in the ADHD group (n=33) | Device: Fall risk<br>* Fall risk, static postural balance and sensorimotor integration were assessed using the Biodex Balance System.<br>* Other names: sensorimotor integration (m-CTSIB) test;|
| treatment group<br>children with ADHD who were treated with MPH for a minimum of 3 months were classified in the treatment group (n=32) | Device: Fall risk<br>* Fall risk, static postural balance and sensorimotor integration were assessed using the Biodex Balance System.<br>* Other names: sensorimotor integration (m-CTSIB) test;|
| control group<br>typically developing children were classified in the third-the control group (n=20) | Device: Fall risk<br>* Fall risk, static postural balance and sensorimotor integration were assessed using the Biodex Balance System.<br>* Other names: sensorimotor integration (m-CTSIB) test;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| postural control | Postural stability tests, including overall stability index (OSI), anterior-posterior stability index (APSI), and medial-lateral stability index (MLSI) | one year | 
| sensorimotor integration | The Modified Clinical Test of Sensory Interaction in Balance (m-CTSIB) testing protocol was used to evaluate sensory integration capabilities and balance. Four different conditions were evaluated for the m-CTSIB test protocol: Eyes Open Firm Surface (EOFS), Eyes Closed Firm Surface (ECFS), Eyes Open Soft Surface (EOSS), and Eyes Closed Soft Surface (ECSS) | one year | 
| Fall risk | Fall risk evaluation by biodex balance system | one year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Attention Deficit Hyperactivity Disorder, Methylphenidate, Postural Balance