Comparison Between Land-based and Water-based Exercises for Knee Osteoarthritis: Randomized Controlled Trial

Study Overview
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Brief Summary
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Forty six patients with knee osteoarthritis will be randomly allocated into two groups: water-based exercises and land-based exercises. Both of them will receive a strengthening exercise protocol for lower limb muscles. A blind investigator will assess the patients before and immediately after, 3 months and 6 months following the interventions. The main outcomes will be pain, function and strength.

Detailed Description
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Forty six patients with knee osteoarthritis will be randomly allocated into two groups: water-based exercises and land-based exercises. Both of them will receive a strengthening exercise protocol for lower limb muscles. A blind investigator will assess the patients before and immediately after, 3 months and 6 months following the interventions. The main outcomes will be pain, function, physical performance and strength.

Official Title
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Comparison Between a Land-based and Water-based Muscles Strengthening Program on Patients With Knee Osteoarthritis Randomized Controlled Trial

Conditions
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Knee Osteoarthritis

Intervention / Treatment
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* Other: water-based exercises
* Other: land-based exercises


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Moderate knee osteoarthritis (grade 2 or 3 using the Kellgren-Lawrence radiograph classification), diagnosed based on clinical and radiological criteria of the American College of Rheumatology No other lower limb and spine musculoskeletal disorders Independent gait Body mass index below 32 Minimum of 4 points in the pain numeric rating scale during climb and descend stairs activities Exclusion Criteria: Cognitive or psychological disorders Neurological disorders History of post-traumatic knee osteoarthritis Knee pain at least 12 months Prior surgery of the lower limbs or spine Fibromyalgia Rheumatoid arthritis Cardiovascular disease Participating in exercise programs and received treatment for the knee at least 3 months

Ages Eligible for Study
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Minimum Age: 50 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Land-based exercises<br>Land-based muscle strengthening exercises protocol | Other: land-based exercises<br>* land-based exercise strengthening protocol for lower limb muscles<br>|
| Experimental: Water-based exercises<br>Water-based muscle strengthening exercises protocol | Other: water-based exercises<br>* water-based exercise strengthening protocol for lower limb muscles<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Function | Pain and Function scores on the Western Ontario and Mcmaster Universities Osteoarthritis Index (WOMAC questionnaire) | 8 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Physical Performance | Physical Performance scores on the Timed Up and GO test (TUG) | 8 weeks | 
| Strength muscle | Strength muscle scores measured by heldheld dynamometer | 8 weeks | 
| Lower Limbs Function | Function Scores on the Lower Extremity Functional Scale (LEFS) | 8 weeks | 
| Pain | Pain Scores on the Numeric Pain Rating Scale | 8 weeks |