Comparison of Postoperative Pain With Two Different Types of Local Anesthesia in Surgery for a Drooping Eyelid

Study Overview
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Brief Summary
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Conjunctival Mullerectomy is a well known procedure used to correct upper lid ptosis via a posterior approach. Patients who undergo this procedure are often given local anesthesia to alleviate intraoperative and postoperative pain. Local anesthesia can be given via frontal nerve block or subconjunctival injection combined with sedation in most cases. Both techniques are currently acceptable options for local anesthesia, however postoperative pain has not been systematically evaluated between these two techniques. The investigators aim to compare intra-operative and postoperative pain with these two techniques in patients undergoing conjunctival Mullerectomy for ptosis repair. Patients will be randomized to receive local anesthesia via frontal nerve block or via subconjunctival injection. In addition, the investigators will measure the surgical outcomes of the ptosis surgery with standard measures.

Official Title
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Comparison of Postoperative Pain With Two Different Types of Local Anesthesia in Surgery for a Drooping Eyelid

Conditions
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Blepharoptosis

Intervention / Treatment
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* Procedure: Frontal nerve block with 2% lidocaine with 1:100,000 dilution of epinephrine
* Procedure: Subconjunctival injection of 2% lidocaine with 1:100,000 dilution with epinephrine


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 18 years of age and older Patient with ptosis that requires correction Patient is able to consent for themselves Exclusion Criteria: Patient unable to complete survey Patient had prior lid surgery Patient taking chronic pain medication

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 100 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Frontal Nerve Block<br>Patients will receive a frontal nerve block for anesthesia | Procedure: Frontal nerve block with 2% lidocaine with 1:100,000 dilution of epinephrine<br>* Frontal Nerve Block 5 cc will be administered preoperatively once.<br>|
| Active Comparator: Subconjucntival Injection<br>Patients will receive a subconjunctival injection for anesthesia | Procedure: Subconjunctival injection of 2% lidocaine with 1:100,000 dilution with epinephrine<br>* Patients will receive a 1.5 cc dose of subconjunctival lidocaine as above<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain control | Patients will be asked to complete a survey regardning pain assessment twenty-four hours after completion of surgery. | 24 hour after surgery | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Efficacy of ptosis surgery | Standard measures include marginal reflex distanced, palpebral fissure and levator fucntion will be used to assess the efficacy of the ptosis surgery and compared to the type of anesthesia the patient was given. | 2 months | 
| Pain Control | completion of survey to assess pain after surgery has been completed. | 1 hour after surgery | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Conjunctival Mullerectomy, Blepharoptosis, Ptosis surgery, Pain Control