The Effect of Regional Anesthesia Techniques on Brain Tissue Oxygenation in Thoracic Surgery

Study Overview
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Brief Summary
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Today, it is preferred that the lung with pathology for thorax surgery is not under ventilation during operation in terms of reliability and ease of operation. For this reason, the anesthesia approach is characteristic and it is ensured that the single lung is not ventilated during the operation by means of specially manufactured intubation tubes. This application can disrupt tissue oxygenation due to both Operation position and single lung ventilation. Thoracic epidural analgesia, which is applied as the gold standard of Thoracic Surgery, is applied prior to the operation and is provided to assist in postoperative analgesia.

Detailed Description
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The aim of this study was to investigate the effect of thoracic epidural analgesia method on brain tissue oxygenation in patients with single lung ventilation.

Official Title
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The Effect of Regional Anesthesia Techniques on Brain Tissue Oxygenation in Thoracic Surgery Operations Where Single Lung Ventilation is Applied

Conditions
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Thoracic Surgery, Epidural Anesthesia, Cerebral Oxygen Saturation

Intervention / Treatment
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* Device: Regional oximetry probe
* Procedure: Thoracic Epidural block


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients who were in the American Society of Anesthesiologists (ASA) I-III class Underwent Thoracic Surgery Exclusion Criteria: Local anesthetic allergy, Bleeding is a diathesis disorder Allergic to the drugs used, Patients who are not reluctant to participate in the study, Presence of infection in the block area, Patients whose body mass index is over 30

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: prospective,randomized
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Group E<br>Thoracic Epidural block + Regional oximetry probe will be placed in the frontal area of the head | Device: Regional oximetry probe<br>* Regional oximetry probe will be placed in the frontal area of the head<br>Procedure: Thoracic Epidural block<br>* Thoracic epidural block will be applied to the patients before the operation begins<br>|
| Sham Comparator: Group P<br>Regional oximetry probe will be placed in the frontal area of the head | Device: Regional oximetry probe<br>* Regional oximetry probe will be placed in the frontal area of the head<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| rso2 | Regional oximetry probe will be placed in the frontal area of the head | peroperative 2 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| po2 | Arterial blood gas oxygen pressure | peroperative 2 hours | 
| ETCO2 | End-tidal carbon dioxide (ETCO2) level | peroperative 2 hours |