Transcranial Stimulation for Upper Limb Training of Individuals With Sequelae From Intracranial Hemorrhage

Study Overview
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Brief Summary
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The purpose of this study is to investigate the effect of transcranial stimulation for upper limb training of patients with sequelae from an intracranial hemorrhage. Patients receive five days of upper limb occupational therapy training in combination with real or sham stimulation. Patients complete the Jebsen Taylor Hand Function Test before, after and 7 days later. The intervention takes place at patients' home address.

Detailed Description
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Aim: To investigate the effect of anodal transcranial direct current stimulation (tDCS) for upper limb training of individuals with sequelae from intracranial hemorrhage. Design: Triple-blinded randomised controlled trial Study population: Patients with intracranial hemorrhage (ICH) of non-traumatic aetiology. Between 6 months and five years from injury. Intervention: Group 1 receive five days of upper limb occupational therapy in combination with anodal stimulation Group 2 receive five days of upper limb occupational therapy in combination with sham stimulation The intervention takes place at patients' home address. Assessment tool: Patients complete the Jebsen Taylor Hand Function Test at baseline, post-intervention and at 7 days follow-up.

Official Title
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Transcranial Direct Current Stimulation for Upper Limb Training of Individuals With Sequelae From Intracranial Hemorrhage

Conditions
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Cerebrovascular Disorders

Intervention / Treatment
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* Device: Transcranial direct current stimulation


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Intracranial hemorrhage Injury between 6 months and 5 years Exclusion Criteria: Traumatic brain injury Other neurological disorders Epilepsy Metal implants in the head

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Transcranial direct current stimulation<br>Anodal stimulation | Device: Transcranial direct current stimulation<br>* Transcranial direct current stimulation of motor cortex<br>|
| Sham Comparator: Sham stimulation<br>30 sek of Transcranial direct current stimulation | Device: Transcranial direct current stimulation<br>* Transcranial direct current stimulation of motor cortex<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change in Jebsen Taylor Hand Function Test | Involves seven items regarding activities of daily living | Change from baseline until 7 days follow-up | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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transcranial stimulation, Intracranial hemorrhage, Home training, Occupational Therapy, Jebsen Taylor Hand Function Test