Serratus-intercostal Plane Block Versus Quadratus Lumborum Block in Nephrectomy: Randomized Study

Study Overview
=================
Brief Summary
-----------------
Performing the nephrectomy by laparoscopy has decrease the incidence of postoperative pain, but there are still some patients who describe a severe pain after this surgery. Regional techniques allow a better recovery quality and adequate- managed pain control.

Detailed Description
-----------------
Adequate control of pain in patients with nephrectomy is a challenge for the anesthesiologist who must achieve an early recovery with minimal adverse effects. Within a multimodal strategy, the work hypothesis is based on comparing the analgesic efficacy of two regional techniques in patients undergoing nephrectomy, in terms of quality of postoperative recovery, pain control, absence of adverse effects and ease of performance.

Official Title
-----------------
Analgesic Effectiveness of the Serratus-intercostal Plane Block Versus Quadratus Lumborum Block in Nephrectomy: Randomized Study

Conditions
-----------------
Kidney Injury

Intervention / Treatment
-----------------
* Device: ultrasound device
* Drug: Levobupivacaine


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: signature of informed consent age > 18 years ASA risk scale < IV Scheduled to nephrectomy. Exclusion Criteria: Patients with cognitive impairment or inability to sign informed consent, Refused to participate Hypersensitivity to the drugs used contraindication of regional technique (coagulopathy, infection) history of chronic pain.

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| SIPB (block)<br>Patients undergone nephectomy and who received SIPB as analgesia | Device: ultrasound device<br>* We performe a differnt analgesic techniques to know if some of then are better<br>* Other names: device;Drug: Levobupivacaine<br>* using the same AL<br>* Other names: drug;|
| QL block<br>Patients undergone nephectomy and who received QL as analgesia | Device: ultrasound device<br>* We performe a differnt analgesic techniques to know if some of then are better<br>* Other names: device;Drug: Levobupivacaine<br>* using the same AL<br>* Other names: drug;|
| control<br>Patients undergone nephrectomy who didn´t receive regional anesthesia | |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| pain control and quality life.VErbal rating scale and QoR15 | Our work hypothesis is based on evaluating whether serratus-intercostal plane block (VNS)(SIPB or modified BRILMA) is similar or better than quadratus lumborum block type 2 (QL2) in items of quality and pain control. | 24 postoperative hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| side effects | Second outcomes will be to value side effects and ease-performing in both techniques (PONV, hipothension, ...) | 48 hours | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
nephectomy, postoperative analgesia, fascial blocks