Dry Eye Response to Interval Exercise and Mediterranean Diet

Study Overview
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Brief Summary
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in the recent times, dry eye was found to be correlated sedentary life style, obesity, hypertension. So, changing the sedentary lifestyle is recommended

Detailed Description
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older patient who will complain from dry eye will be collected. it is planned to recruit 60 elderly (with obesity and hypertension) to be distributed into group 1 (this group will receive 3-time interval exercise per the week, applied for 30 min with high intensity, plus Mediterranean Diet) and group 2 (this group will receive only 3-time interval exercise per the week, applied for 30 min with high intensity). Every group will contain 30 elderly

Official Title
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Dry Eye Response to Interval Exercise (High Intensity Aerobic Activity) and Mediterranean Diet

Conditions
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Dry Eye, Diet Habit, Physical Inactivity

Intervention / Treatment
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* Behavioral: lifestyle change
* Other: exercise


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: elderly patients with dry eye complaints the patients will be obese and hypertensives Exclusion Criteria: heart or respiration problems other diagnosed eye or systemic diseases

Ages Eligible for Study
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Minimum Age: 65 Years
Maximum Age: 75 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: group 1<br>30 older patient who will complain from dry eye will receive 3-time interval exercise per the week, applied for 30 min with high intensity, plus Mediterranean Diet for 6 months | Behavioral: lifestyle change<br>* 30 older patient who will complain from dry eye will receive 3-time interval exercise per the week, applied for 30 min with high intensity, plus Mediterranean Diet for 6 months<br>|
| Active Comparator: group 2<br>30 older patient who will complain from dry eye will receive 3-time interval exercise per the week, applied for 30 min with high intensity, for 6 months | Other: exercise<br>* 30 older patient who will complain from dry eye will receive 3-time interval exercise per the week, applied for 30 min with high intensity, for 6 months<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Schirmer's test | tear-production speed test | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| scoring system for dry eye | it is a questionnaire will assess dry-eye severity | 6 months | 
| Ocular surface disability index | it is a questionnaire will assess complaints of patients due to severity of dry-eye | 6 months | 
| tear film break up time testing | it is a test that will assess tear film stabilization | 6 months | 
| Oxford grading system | a test will examine ocular epithelial damage | 6 months | 
| blood systole | it will be measured by sphygmomanometer | 6 months | 
| blood diastole | it will be measured by sphygmomanometer | 6 months | 
| weight | it will be expressed in kilograms | 6 months | 
| body mass index | it will be gained by dividing weight of subject on his or her squared height | 6 months | 
| waist circumference | it will be evaluated by tape measurements of treatment | 6 months |