The German Keratoplasty Registry of the German Ophthalmological Society (DOG)

Study Overview
=================
Brief Summary
-----------------
Aim of this study is to reflect on the changing trends in absolute numbers, surgical techniques and indications of corneal transplantations being performed in Germany. In 2017, the Section Cornea of the German Ophthalmological Society provides an interim-assessment about the most up-to-date results of this long-term study over a period of sixteen years between 2001 and 2016.

Official Title
-----------------
Trends in Corneal Transplantation From 2001 to 2016 in Germany: A Report of the DOG-Section Cornea and Its Keratoplasty Registry

Conditions
-----------------
Corneal Transplantation

Intervention / Treatment
-----------------
* Procedure: Corneal transplantation


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: All patients in Germany treated with the different types of corneal transplantation from 2001 to 2016. Exclusion Criteria: Patients without corneal transplantation.

Ages Eligible for Study
-----------------
Minimum Age: 1 Year
Maximum Age: 100 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients with corneal transplantation<br>Aim is to include all patients in Germany treated with the different types of corneal transplantation with an interim-assessment of the period between 2001 and 2016. | Procedure: Corneal transplantation<br>* PKP: Penetrating Keratoplasty DALK: Deep Anterior Lamellar Keratoplasty DMEK: Descemet Membrane Endothelial Keratoplasty DSAEK: Descemet's Stripping Automated Endothelial Keratoplasty<br>* Other names: PKP, DALK, DMEK, DSAEK;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| An overview about absolute numbers of corneal transplantation in Germany from 2001 to 2016. | A questionnaire about absolute numbers of corneal transplantation per year was sent to the 111 ophthalmological departments in Germany performing corneal transplantation. Data has been collected annually over a period of sixteen years in Germany between 2001 and 2016. | 01/01/2001 to 31/12/2016 | 
| An overview about trends in the various types of corneal transplantation in Germany from 2001 to 2016. | The questionnaire also records the types of corneal transplantation (i.e. penetrating keratoplasty, deep anterior lamellar keratoplasty, Descemet membrane endothelial keratoplasty (DMEK) and Descemet's stripping automated endothelial keratoplasty DSAEK) allowing a discussion of trends in corneal transplantation. Data has been collected annually over a period of sixteen years in Germany between 2001 and 2016. | 01/01/2001 to 31/12/2016 | 
| An overview about indications for corneal transplantation in Germany from 2001 to 2016. | The questionnaire also records the indications for corneal transplantation (e.g. Fuchs' endothelial corneal dystrophy, pseudophakic corneal decompensation, repeated keratoplasty after graft failure, keratoconus and corneal scarring). Data has been collected annually over a period of sixteen years in Germany between 2001 and 2016. | 01/01/2001 to 31/12/2016 | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Keratoplasty Registry, PKP, DSAEK, DMEK, DALK