Persistent Postoperative Pain After Major Emergency Abdominal Surgery

Study Overview
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Brief Summary
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Perioperative pain is one of the most significant complaints and problems for patients undergoing major open surgery. Pain after surgery carry an abundance of consequences such as reduced mobilization, reduced nutrition intake, reduced pulmonary capacity and increased risk of complications and length of hospitalization. The literature does not supply much information on short- or longer-term outcomes of pain treatment for emergency surgery. The investigators know that for planned surgery in general around 10-50 percentage suffer from persistent postoperative pain. It is therefore important to follow-up on the longer-term outcomes after the standardized analgesic pain treatment. Based on a predefined patient group called OMEGA (Optimizing Major EMergency Abdominal surgery) the investigators hypothesize that OMEGA patients will present a significant incidence rate of patients with persistent postoperative pain and/or continued opioid/non-opioid usage. Therefore this study is to investigate the incidence of prolonged postoperative pain and opioid/non-opioid consumption in OMEGA patients at 3 month after major emergency abdominal surgery.

Official Title
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Persistent Postoperative Pain After Major Emergency Abdominal Surgery

Conditions
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Chronic Postoperative Pain

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: OMEGA patients (patients who have undergone major emergency abdominal surgery including the stomach, small or large bowel, or rectum for conditions such as perforation, ischemia, abdominal abscess, bleeding or obstruction) Age 18 or more Surgery performed within 72 hours of an acute admission or as an acute re-operation Exclusion Criteria: Elective laparoscopy Diagnostic laparotomy/laparoscopy where no subsequent procedure is performed Non-elective hernia repair without bowel resection Admission or transfer to an intensive care unit

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| OMEGA<br>Patients who have undergone major emergency abdominal surgery including the stomach, small or large bowel, or rectum for conditions such as perforation, ischemia, abdominal abscess, bleeding or obstruction. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain Mobilization | Pain during mobilization last week based on a self-made questionary | Data is collected 3 months postoperative | 
| Opioids | Daily opioid usage last week based on a self-made questionary | Data is collected 3 months postoperative | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Pain Rest | Pain in rest last week based on a self-made questionary | Data is collected 3 months postoperative | 
| Non-opiod Analgesic | Non-opioid analgesic usage based on a self-made questionary | Data is collected 3 months postoperative | 
| Barthel-20 Index | Simple function measurement based on daily living Simple function measurement | Data is collected 3 months postoperative | 
| EuroQol-5 | Health related quality of life | Data is collected 3 months postoperative | 
| Montreal Cognitive Assessment test (Mini-MoCA) | Cognitive function | Data is collected 3 months postoperative |