Validation Study of the Malay Version of 3D-CAM

Study Overview
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Brief Summary
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Validation of the Malay version of 3D-CAM, involving two-staged process. Translation and cultural adaptation of 3D-CAM into the Malay language. Testing for Validity and Reliability of the translated 3D-CAM tool to detect postoperative delirium.

Detailed Description
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Translation and Cultural Adaptation The research panel, who consisted of experts in the clinical field of anesthesia, did the meticulous process of translation and cultural adaptation of 3D-CAM. This process included independent translation by the research panel, reconciliation of two independent translated 3D-CAM, ethics approval prior to pilot study on 20 relevant subjects, back translation into English and finalizing the Malay version of 3D-CAM for the next phase of testing. Testing for Validity and Reliability of the translated 3D-CAM tool Patients were recruited pre-operatively after reading the patient's information sheet and signing the informed consent. Post-operatively, two trained assessors separately administered the Malay 3D-CAM on the recruited patients. One of the trained assessors administered the original 3D-CAM on the same patients at a different time. Standard reference of diagnosing delirium was made by a psychiatrist using the DSM V criteria, after interviewing the patients. For validity, the diagnosis of delirium made using the Malay 3D-CAM tool was tested against the standard reference for diagnosing delirium according to the DSM V criteria made by a psychiatrist For inter-rater reliability, the diagnosis of delirium made by two trained assessors using the Malay 3D-CAM tool were statistically compared. For parallel reliability, the diagnosis of delirium made using the Malay 3D-CAM was compared to the original English version of 3D-CAM.

Official Title
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Validation Study of the Malay Version of the 3-Minute Diagnostic Interview for Confusion Assessment Method Defined Delirium (3D-CAM)

Conditions
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Postoperative Delirium, Diagnosis, Psychiatric

Intervention / Treatment
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* Diagnostic Test: Malay 3D-CAM diagnostic tool 1
* Diagnostic Test: Malay 3D-CAM Diagnostic tool 2


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 65 years old and above Patients undergoing non-cardiac surgery Exclusion Criteria: Patients undergoing cardiac Surgery Unable to communicate in the Malay Language Patients who were in the intensive care unit peri-operatively Patients whose surgery was cancelled Patients who were deaf and dumb Patients who had been diagnosed as delirious or has psychosis history before assessment Glasgow Coma Scale of < 12 / 15 Patients who remained comatose throughout the investigation

Ages Eligible for Study
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Minimum Age: 65 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Diagnostic
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Delirium<br>Diagnosis of delirium according to 5th Edition of The Diagnostic and Statistical Manual of Mental Disorders (DSM-5) by Psychiatrist. | Diagnostic Test: Malay 3D-CAM diagnostic tool 1<br>* Assessor 1 uses Malay 3D-CAM to detect Delirium<br>Diagnostic Test: Malay 3D-CAM Diagnostic tool 2<br>* Assessor 2 uses Malay 3D-CAM to detect Delirium<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Construct Validity | Assess validity of the translated Malay 3D-CAM to Standard Reference for Diagnosis of Delirium | 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Inter-rater Reliability | Assess the inter-rater reliability of 2 trained assessor using the Malay 3D-CAM | 3 months | 
| Parallel Reliability | Assess the parallel reliability of using Malay 3D-CAM to the original version of 3D-CAM | 3 months | 
| Factors associated with post-operative delirium | Assess factors associated with post-operative delirium | 3 months |