Impact of Hysterectomy on Quality of Life and Urethral Length

Study Overview
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Brief Summary
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To establish the impact of hysterectomy on sexual function, urethral length and quality of life

Detailed Description
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The investigators evaluate impact of total hysterectomy (abdominal, by laparoscopy and vaginal) and supracervical hysterectomy (abdominal and by laparoscopy) on quality of life, sexual function, urethral length and urinary incontinence. The patients fulfill questionnaires (UDI 6, IIQ7, FSFI and ICIQ) before operation and 6 months after. Additionally the investigators measure urethral length before procedure and 6 months after.

Official Title
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Impact of Hysterectomy and Supracervical Hysterectomy on Quality of Life, Urinary Incontinence and Urethral Length

Conditions
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Fibroid Uterus, Urethral Diseases, Sex Disorder

Intervention / Treatment
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* Procedure: urethral length measure


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: patients qualified to hysterectomy due to benign condition Exclusion Criteria: serious health condition previous vaginal operations

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 70 Years

Sexes Eligible for Study
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Female

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| TAH<br>patients before and after total abdominal hysterectomy (TAH) | Procedure: urethral length measure<br>* measure of urethral length, distribution of questionnaires before and after operation<br>* Other names: ICIQ questionnaire;|
| TLH<br>patients before and after total laparoscopic hysterectomy (TLH) | Procedure: urethral length measure<br>* measure of urethral length, distribution of questionnaires before and after operation<br>* Other names: ICIQ questionnaire;|
| TVH<br>patients before and after total vaginal hysterectomy (TVH) | Procedure: urethral length measure<br>* measure of urethral length, distribution of questionnaires before and after operation<br>* Other names: ICIQ questionnaire;|
| SAH<br>patients before and after abdominal supracervical hysterectomy (SAH) | Procedure: urethral length measure<br>* measure of urethral length, distribution of questionnaires before and after operation<br>* Other names: ICIQ questionnaire;|
| SLH<br>patients before and after supracervical laparoscopic hysterectomy (SLH) | Procedure: urethral length measure<br>* measure of urethral length, distribution of questionnaires before and after operation<br>* Other names: ICIQ questionnaire;|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change from Baseline urethral length at 6 months after hysterectomy | Comparison of urethral length before and after hysterectomy. Urethra will be measured during ultrasound examination in millimeters | 6 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Change from Baseline in sexual functions at 6 months after hysterectomy | The patients fulfill FSFI questionnaire before and after hysterectomy. Range 2-36 with higher scores indicating better sexual function. | 6 months | 
| Change from Baseline in appearance of urinary incontinence at 6 months after hysterectomy | The patients fulfill UDI 6 (range 0-400) questionnaire to assess appearance of urinary incontinence before and after hysterectomy | 6 months | 
| Change from Baseline in impact of urinary incontinence at 6 months after hysterectomy | The patients fulfill IIQ 7 (range 0-400) questionnaire to assess impact of hysterectomy on urinary incontinence. | 6 months | 
| Change from Baseline in urinary tract symptoms at 6 months after hysterectomy | The patients fulfill ICIQ questionnaire to assess impact of hysterectomy on urinary tract symptoms | 6 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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quality of life, urethral length, sexual function