Frequency of Parasite Infestation in Patients With Chronic Spontaneous Urticaria

Study Overview
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Brief Summary
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The goal of this study is to describe the prevalence and the type of parasite in patients with a chronic spontaneous urticaria as well as to describe the associations between parasitic disease and the characteristics of the patients, for example eosinophilia.

Official Title
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Häufigkeit Der Infestation Mit Parasiten Bei Patienten Mit Chronisch Spontaner Urtikaria, Eine Retrospektive Datenanalyse

Conditions
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Chronic Spontaneous Urticaria, Parasitic Disease

Intervention / Treatment
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* Diagnostic Test: Examination of stool samples


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Diagnosis of a chronic spontaneous urticaria Age: 17 years old and up Exclusion Criteria: No diagnosis of a chronic spontaneous urticaria Age: younger than 17 years

Ages Eligible for Study
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Minimum Age: 17 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Patients diagnosed with a chronic spontaneous urticaria<br>Patients with a chronic spontaneous urticaria who were being treated at the allergology of the university hospital Basel between the 1st of June and the 30th of September | Diagnostic Test: Examination of stool samples<br>* Tests for diagnosis of parasitic diseases<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of patients with parasite infestation | assess number of patients with chronic spontaneous urticaria that have a parasite infestation (Analysis of stool samples by the Swiss Tropical and Public Health Institute (TPH), Basel) | Patients with a chronic spontaneous urticaria that were treated at the University hospital basel between the 1st of June 2019 and the 30th of September 2019 | 
| Most common parasite subgroup | subtype determination from stool samples was performed by the Swiss TPH, Basel by polymerase chain reaction (PCR) | Patients with a chronic spontaneous urticaria that were treated at the University hospital basel between the 1st of June 2019 and the 30th of September 2019 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Correlation between migration Background/ travel history of the patients and parasite infestation | examine travel history and migration background of patients | Patients with a chronic spontaneous urticaria that were treated at the University hospital basel between the 1st of June 2019 and the 30th of September 2019 | 
| Correlation between gastrointestinal complaints of the patients and parasite infestation | anamnesis of the patients | Patients with a chronic spontaneous urticaria that were treated at the University hospital basel between the 1st of June 2019 and the 30th of September 2019 | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Chronic Spontaneous Urticaria, Parasitic disease