The Comparison of Cognition, Depression and Anxiety, and Quality of Life After Hip Fracture Surgery Under General or Regional Anesthesia

Study Overview
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Brief Summary
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Postoperative cognitive dysfunction is a relatively common in elderly patients after hip surgery, but exact mechanism of its onset is still unclear as well as contributing factors. There is also increased incidence of depression and anxiety. Both affect the recovery after surgery, slow it down and reduce the quality of life. Patients will be divided into two groups, operated under regional anaesthesia and operated under general anaesthesia, and monitored after surgery. Patients will be tested before and after surgery to evaluate postoperative cognitive deficits, depression and anxiety scale and health-related quality of life questionnaire.

Official Title
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The Comparison of Cognitive Function, Symptoms of Depression and Anxiety, and Quality of Life in Patients After Hip Fracture Surgery Under General or Regional Anesthesia

Conditions
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Postoperative Cognitive Dysfunction, Hip Fractures, Depression, Anxiety, Quality of Life

Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients intended for surgical treatment of hip fractures ≥ 60 years Patients who are category ASA I to ASA III will be included in research Sufficient cognitive ability Only those patients who have agreed to be participants in the research and have signed the consent for participation and informed consent. Exclusion Criteria: Patients who refused to participate in the survey and who did not sign informed consent Patients with ASA IV or more Patients under 60 years Severe psychiatric disorders involving the use of psychopharmaceuticals back three months All patients who have other fractures in addition to hip fractures Polytrauma All patients scheduled for more than one surgical intervention during the procedure, or within the next 8 weeks Patients who have been diagnosed with dementia, and / or are receiving anti-dementia drugs

Ages Eligible for Study
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Minimum Age: 60 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Group with regional anaesthesia<br> | |
| Group with general anaesthesia<br> | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| change in cognition | MoCA scale (Montreal Cognitive Assessment), F-A-S test | preoperatively/postoperative follow up 2 months | 
| change in anxiety and depression | The HAD Scale (The Hospital Anxiety and Depression Scale) | preoperatively/postoperative follow up 2 months | 
| change in quality of life | EQ-5D-5L Questionnaire | preoperatively/postoperative follow up 2 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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hip fracture surgery, regional anaesthesia, general anaesthesia, postoperative cognitive dysfunction, depression, anxiety, quality of life