Effects of Ground-based Walking Training in Pulmonary Hypertension

Study Overview
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Brief Summary
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Pulmonary Hypertension (PH) is a hemodynamic and physiopathological condition that is defined as an increase in pulmonary artery pressure ≥25 mmHg when measured at resting with symptoms such as dyspnea, fatigue, chest pain, and syncope. PH characterized by decreased exercise capacity, quality of life, peripheral muscle strength, balance, and physical inactivity. It is recommended that patients with PH should be included in cardiopulmonary rehabilitation programs in addition to medical treatment. Ground-based walking training is a safe and effective method for COPD patients. In the literature, there are no studies evaluating the effects of ground-based walking training in PH patients.

Detailed Description
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The aim of this project is to determine the effect of ground-based walking training on physical activity, exercise capacity, balance, peripheral muscle strength and quality of life in patients with PH.

Official Title
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A Randomized Controlled Trial of Ground-based Walking Training for Adult Patients With Pulmonary Hypertension

Conditions
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Pulmonary Hypertension

Intervention / Treatment
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* Other: Ground-based walking training


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 18-80 years Diagnosed with PH Followed by the department of chest diseases at least six months Not participating in the rehabilitation program in last year Exclusion Criteria: Functional group four due to WHO functional classification PH due to left heart diseases, PH due to lung diseases and/or hypoxia Treatment and medication change in the last three months Cooperation problems Patients with successful pulmonary endarterectomy operation Smoking Patients with uncontrolled cardiovascular diseases Patients with orthopeadic and/or neurologic disorders that could limit exercise tests Syncope history in recent

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Training Group<br>Training group will attend ground-based walking training under the supervision of a physiotherapist for 2 days and 30 minutes a week. Patients will walk for 1-2 days in a week without supervision. | Other: Ground-based walking training<br>* Patients will attend a 2-day 30-minute ground-based walking training under the supervision of a physiotherapist. Patients will walk for 1-2 days in a week without supervision. According to the Modified Borg Scale, the dyspnea intensity will be 3-4 (medium to slightly difficult) and the heart rate will be completed to not exceed 120 min / pulse. Heart rate of patients will be followed by finger type pulse oximeter<br>|
| No Intervention: Control Group<br>Patient education will be given and no intervention will be made. | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Endurance exercise capacity | endurance shuttle walk test | 8 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Pulmonary Hypertension, Walking Training, Exercise, Balance, Quality of Life