Academic Detailing About Asthma

Study Overview
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Brief Summary
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General practices in the Capital Region of Denmark are offered a short educational visit and are randomized to either asthma (intervention) or another topic (control). The change in prescription pattern from before to after the visit is compared between the intervention and control group.

Detailed Description
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General practices in the Capital Region of Denmark are offered a short educational visit. They are randomized by address to be offered a visit about either asthma (intervention) or another topic (control). The prescription pattern of each general practice (as seen by their regional registration number [ydernummer]) who receive a visit is investigated. The change in prescription pattern from before to after the visit is compared between the intervention and control group.

Official Title
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Boosting General Practice pRescription by Individual Educational Fast Academic Detailing Visits About Asthma

Conditions
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Prescription Pattern

Intervention / Treatment
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* Behavioral: asthma education
* Behavioral: Other education


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: General practices in the capital region of denmark, who owns a regional registration number [ydernummer] Want a visit Have time for a visit within the study period Exclusion Criteria: -
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Health Services Research
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: randomized placebo controlled study
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: asthma education<br>The general practices in this arm will receive the education visits about asthma. | Behavioral: asthma education<br>* A 15 minutes (preferable) one-on-one educational visit about asthma treatment. The main points being: Every person with asthma should be treated with inhaled corticosteroids (ICS). Most patients with asthma should be treated with Bufomix Easyhaler either as needed and/or regularly. Patients should not use short-acting bega2-agonist (SABA) unless they use a medium-ICS-dosis.<br>|
| Placebo Comparator: Other education<br>The general practices in this arm will receive an educational visit on another topic (PPI). | Behavioral: Other education<br>* A 15 minutes (preferable) one-on-one educational visit about another topic (NOT asthma).<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Difference in change of prescription of inhaled corticosteroids and long-acting beta2-agonist (ICS+LABA) before and after educational visit in a six months period | Difference in change of number of adult patients with prescriptions on ICS+LABA between asthma-group and placebo-group. | 6-0 months before and 6-12 months after educational visit | 
| Difference in change of prescription of ICS and SABA (as monotherapy) before and after educational visit in a six months period | Difference in change of number of adult patients with prescriptions on ICS and SABA as monotherapy to adults between asthma-group and placebo-group. | 6-0 months before and 6-12 months after educational visit | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Difference in change of prescription of ICS+LABA before and after educational visit in one year | Difference in change of number of adult patients with prescriptions on ICS+LABA between asthma-group and placebo-group | one year before and one year after educational visit | 
| Difference in change of prescription of ICS+LABA before and after educational visit in one year as interrupted time series analysis | Difference in change of number of adult patients with prescriptions on ICS+LABA between asthma-group and placebo-group as interrupted time series analysis | one year before and one year after educational visit | 
| Difference in change of prescription of ICS+LABA before and after educational visit in one year for each month | Difference in change of number of adult patients with prescriptions on ICS+LABA between asthma-group and placebo-group analyzed by each month in relation to the visit | one year before and one year after educational visit | 
| Difference in change of prescription of ICS and SABA (as monotherapy) before and after educational visit one year | Difference in change of number of adult patients with prescriptions on ICS or on SABA as monotherapy to adults between asthma-group and placebo-group. | one year before and one year after educational visit | 
| Difference in change of prescription of ICS and SABA (as monotherapy) before and after educational visit one year as interrupted time series analysis | Difference in change of number of adult patients with prescriptions on ICS or on SABA as monotherapy to adults between asthma-group and placebo-group as interrupted time series analysis | one year before and one year after educational visit | 
| Difference in change of prescription of ICS and SABA (as monotherapy) before and after educational visit one year for each month | Difference in change of number of adult patients with prescriptions on ICS and on SABA as monotherapy to adults between asthma-group and placebo-group analyzed by each month in relation to the visit | one year before and one year after educational visit | 
| Difference in change of prescription of the Easyhaler Device before and after educational visit in a six months period | Difference in change of number of adult patients with prescription on the Easyhaler Device between asthma-group and placebo-group | 6-0 months before and 6-12 months after educational visit | 
| Difference in change of prescription of the Easyhaler Device before and after educational visit in one year | Difference in change of number of adult patients with prescription on the Easyhaler Device between asthma-group and placebo-group | one year before and one year after educational visit | 
| Difference in change of prescription of the Easyhaler Device before and after educational visit as interrupted time series analysis | Difference in change of number of adult patients with prescription on the Easyhaler Device between asthma-group and placebo-group as interrupted time series analysis | one year before and one year after educational visit | 
| Difference in change of prescription of the Easyhaler Device before and after educational visit for each month | Difference in change of number of adult patients with prescription on the Easyhaler Device between asthma-group and placebo-group analyzed by each month in relation to the visit | one year before and one year after educational visit | 
| Difference in change of prescription of long-acting muscarinic antagonist (LAMA) before and after educational visit in a six months period | Difference in change of number of adult patients with prescription on LAMA between asthma-group and placebo-group | 6-0 months before and 6-12 months after educational visit | 
| Difference in change of prescription of LAMA before and after educational visit in one year | Difference in change of number of adult patients with prescription on LAMA between asthma-group and placebo-group | one year before and one year after educational visit | 
| Difference in change of prescription of LAMA before and after educational visit as interrupted time series analysis | Difference in change of number of adult patients with prescription on LAMA between asthma-group and placebo-group | one year before and one year after educational visit | 
| Difference in change of prescription of LAMA before and after educational visit for each month | Difference in change of number of adult patients with prescription on LAMA between asthma-group and placebo-group analyzed by each month in relation to the visit | one year before and one year after educational visit | 
| Difference in change of cost of each medication group before and after educational visit in a six months period | Difference in change of cost (pharmacy retail price) of SABA, ICS, ICS+LABA, LAMA and ICS+LAMA+LABA to adults between asthma-group and placebo-group | 6-0 months before and 6-12 months after educational visit | 
| Difference in change of cost of each medication group before and after educational visit in one year | Difference in change of cost (pharmacy retail price) of SABA, ICS, ICS+LABA, LAMA and ICS+LAMA+LABA to adults between asthma-group and placebo-group | one year before and one year after educational visit | 
| Difference in change of cost of each medication group before and after educational visit as interrupted time series analysis | Difference in change of cost (pharmacy retail price) of SABA, ICS, ICS+LABA, LAMA and ICS+LAMA+LABA to adults between asthma-group and placebo-group | one year before and one year after educational visit | 
| Difference in change of cost of each medication group before and after educational visit for each month | Difference in change of cost (pharmacy retail price) of SABA, ICS, ICS+LABA, LAMA and ICS+LAMA+LABA to adults between asthma-group and placebo-group analyzed by each month in relation to the visit | one year before and one year after educational visit |