Inter-rater Reliability of the Australian Spasticity Assessment Scale (ASAS) in Post-stroke Spasticity

Study Overview
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Brief Summary
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The reliability of the Australian Spasticity Assessment Scale (ASAS) has been reported to be not high enough in adult patients with acquired brain damage. The low number of patients and the heterogeneous study population have been reported as important limitations in the reliability study of this measure. Therefore, the reliability of the ASAS needs to be confirmed in stroke patients with spasticity. This study aims to investigate the inter-rater reliability of the ASAS in a study population consisting of a larger and more homogeneous patient population (those with post-stroke spasticity).

Detailed Description
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Spasticity is a motor disorder characterized by a velocity-dependent increase in tonic stretch reflex due to upper motor neuron lesion. The prevalence of post-stroke spasticity is between 17-40%. In the assessment of spasticity, although biomechanical and neurophysiological methods provide quantitative data, semi-quantitative methods are mostly used clinically. The most frequently used spasticity measures are the Modified Ashworth Scale and the Modified Tardieu Scale. However, these methods have significant disadvantages. Therefore, the search for more reliable clinical measures continues. One of the newly developed clinical scales is called the Australian Spasticity Assessment Scale (ASAS). Although ASAS has been reported to have a high level of reliability in children with cerebral palsy, the same has not been detected in adult patients with acquired brain damage. The low number of patients and the heterogeneous study population have been reported as two of the important limitations in the reliability study of this measure. In this study, researchers aim to investigate the inter-rater reliability of the ASAS in a study population consisting of a larger and more homogeneous patient population (those with post-stroke spasticity).

Official Title
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Inter-rater Reliability of the Australian Spasticity Assessment Scale (ASAS) in Post-stroke Spasticity

Conditions
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Hemiplegia, Spastic

Intervention / Treatment
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* Other: Australian Spasticity Assessment Scale


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Chronic stroke (> 6 months) Fist stroke Increased tone according to the Modified Ashworth Scale in at least one of the elbow, wrist, and ankle Stability of spasticity for the last 3 months Exclusion Criteria: Increased tone due to causes other than stroke (traumatic brain injury, spinal cord injury, multiple sclerosis, motor neuron disease, etc.) Acute or subacute stroke (≤6 months) Recurrent stroke attacks Presence of contracture and/or moderate to severe pain in the joints to be assessed (elbow, wrist, and ankle) Botulinum toxin injection in the last three months History of neurolysis for spasticity (alcohol or phenol) History of surgery for spasticity Initiation of a new drug for spasticity, or a change in drug dose

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Researcher 1<br>The first researcher assessing elbow, wrist, and ankle spasticity, respectively | Other: Australian Spasticity Assessment Scale<br>* Australian Spasticity Assessment Scale is a clinical measure to assess the severity of spasticity<br>|
| Researcher 2<br>The second researcher assessing elbow, wrist, and ankle spasticity, respectively | Other: Australian Spasticity Assessment Scale<br>* Australian Spasticity Assessment Scale is a clinical measure to assess the severity of spasticity<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Australian Spasticity Assessment Scale (ASAS) | The ASAS is an ordinal scale with five levels (0, 1, 2, 3, 4). The severity of spasticity increases as the level-ups.The contracture is assessed separately. Level 0 means no catch on rapid passive stretch (no spasticity), and level 4 means that the body part is fixed on the rapid passive stretch but moves on the slow passive stretch. In level 1, a catch followed by a release occurs on the rapid passive stretch. In level 2, the catch is in the second half of the range, and there is a resistance in the remaining range of motion. In level 3, the catch is in the first half of the range, and there is a resistance in the remaining range of motion. | Through study completion, an average of 2 year | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Hemiplegia, spasticity, upper limb