linjc16/ctgov huggingface dataset:
Carbetocin Versus Oxytocin for Prevention of Postcesarean Hemorrhage in Pregnancy With High Risk for PPH

Study Overview
=================
Brief Summary
-----------------
Objective: study efficacy of carbtocin versus oxytocin for prevention postpartum hemorrhage in high risk pregnancy who undergo cesarean section

Detailed Description
-----------------
Randomized controlled clinical trial. Defined patient in two group. Primary outcome is evaluate additional drug use Secondary outcome is evaluated estimated blood loss, hemoglobin level

Official Title
-----------------
Carbetocin Versus Oxytocin for Prevention of Postcesarean Hemorrhage in Pregnant Women With High Risk Postpartum Hemorrhage: a Randomized Controlled Trial

Conditions
-----------------
Postpartum Hemorrhage, Cesarean Section, High Risk Pregnancy

Intervention / Treatment
-----------------
* Drug: Carbetocin
* Drug: oxytocin


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: previous history of postpartum hemorrhage polyhydramnios fetal macrosomia previous cesarean section grand multiparity intramural myoma chorioamnionitis prolonged premature rupture of membrane augmentation of labour Exclusion Criteria: pregnancy induce hypertension on anticoagulant placenta previa or placenta percreta

Ages Eligible for Study
-----------------
Minimum Age: 18 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: protocal A<br>Carbetocin versus placebo | Drug: Carbetocin<br>* carbetocin 100 mcg + RLS solution 10 ml injected directly into the vein over 2 min<br>Drug: oxytocin<br>* oxytocin 20 IU diluted in 1000 ml of RLS solution administered intravenously at rate 120 ml/hr x 8 hr<br>|
| Active Comparator: protocal B<br>Oxytocin versus placebo | Drug: Carbetocin<br>* carbetocin 100 mcg + RLS solution 10 ml injected directly into the vein over 2 min<br>Drug: oxytocin<br>* oxytocin 20 IU diluted in 1000 ml of RLS solution administered intravenously at rate 120 ml/hr x 8 hr<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Additional drug use | Number of additional drug use after intervention drug | during intra-operation | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Estimate blood loss | amount of blood loss | During intra-opeartion and acute post operation period as 24 hours post operation | 
| Side effect | type of side effect | During intra-opeartion and acute post operation period as 24 hours post operation | 
| Hemoglobin level | differentiation of hemoglobin | Pre-operation and 24 hours post operation |
Efficacy of Preoperative Nutritional Support on Postoperative Outcome in Gastric Cancer Patients at Nutritional Risk by NRS-2002

Study Overview
=================
Brief Summary
-----------------
Evaluation of the impact of preoperative nutritional support on clinical outcomes in patients at nutritional risk. The primary endpoint was the complication rate and the second endpoint was the length of stay.

Official Title
-----------------
Efficacy of Preoperative Nutritional Support on Postoperative Outcome in Gastric Cancer Patients at Nutritional Risk by NRS-2002- A Prospective, Randomized Clinical Trial

Conditions
-----------------
Malnutrition, Gastric Cancer

Intervention / Treatment
-----------------
* Dietary Supplement: carbohydrates
* Dietary Supplement: vitamins


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: clinical diagnosis of gastric cancer surgery preoperative stage Exclusion Criteria: neoadjuvent chemoradiation pregnant advanced stage

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 85 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Active Comparator: Enteral<br>Enteral nutrition composed of carbohydrates and vitamins | Dietary Supplement: carbohydrates<br> <br> Dietary Supplement: vitamins<br> <br> |
| Active Comparator: Parenteral<br> | Dietary Supplement: carbohydrates<br> <br> Dietary Supplement: vitamins<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Infectious complication |  | 30 days | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Length of hospital stay |  | 30 days | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Malnutrition, Gastric cancer, preoperative nutrition
Construct Validity, Responsiveness, and Demographic Predictors of the IAPCC-SV

Study Overview
=================
Brief Summary
-----------------
There are three purposes for this study: I. to establish the construct validity (via factor analysis) of the Inventory for Assessing the Process of Cultural Competence Among Healthcare Professionals - Student Version (IAPCC-SV) II. to determine the responsiveness of the IAPCC-SV III. to investigate demographic predictor variables of the IAPCC-SV It is hypothesized that: I. the variables will load on only one component, with each component being represented by a number of strongly loaded variables II. the IAPCC-SV will demonstrate responsiveness, evidenced by significantly higher post-module IAPCC-SV scores of the experimental group when compared to the control group III. the cultural composite score and race will be significant predictors of IAPCC-SV score

Official Title
-----------------
Construct Validity, Responsiveness, and Demographic Predictors of the Inventory for Assessing the Process of Cultural Competence Among Healthcare Professionals - Student Version (IAPCC-SV)

Conditions
-----------------
Cultural Competence

Intervention / Treatment
-----------------
* Other: Cultural Competence Education module


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: First semester PT students at Texas State will be eligible to participate in the study Exclusion Criteria: Students previously enrolled in a PT education program will be excluded from this study.
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Cultural Competence Module<br>The module will include lecture, case studies, and discussion of cultural competence. | Other: Cultural Competence Education module<br>* A four hour cultural competence education module including lecture, case studies, and discussion of cultural competence.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Inventory for Assessing the Process of Cultural Competence Among Healthcare Professionals - Student Version (IAPCC-SV) Score |  | pre and post module |
Image Collection of Normal Eyes for Development of an EU RDB

Study Overview
=================
Brief Summary
-----------------
This study is designed to collect in-tissue OCT scans on the Optos P200TE on normal healthy eyes to develop a EU reference database

Official Title
-----------------
Image Collection of Normal Eyes on the Optos P200TE for Development of an EU Reference Database

Conditions
-----------------
Healthy

Intervention / Treatment
-----------------
* Device: P200TE


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Subject 22 years of age or older on the date of informed consent Subject able to understand the written informed consent and willing to participate as evidenced by signing the informed consent Subject presenting at the site with normal eyes* (Cataracts and LASIK and PRK are allowed) BCVA 20/40 or better (each eye) Subject is able to comply with the study procedures in the view of the investigator *Normal eyes are defined as eyes judged normal for the subjects age as determined by the PI or sub-investigator Exclusion Criteria: 1.1. Subject unable to tolerate ophthalmic imaging 2. Subject with ocular media not sufficiently clear to obtain acceptable OCT images 3. History of leukemia, dementia or multiple sclerosis

Ages Eligible for Study
-----------------
Minimum Age: 22 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Other
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: Single<br> | Device: P200TE<br>* OCT images<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Retinal thickness | In general, descriptive statistics (n, mean, standard deviation, median, minimum and maximum) and 95% confidence interval for the mean will be used to summarize each scan parameters. The 1st, 5th, 95th and 99th percentile results will be tabulated. All percentile results will be incorporated in the device software. | 1 day |
Phospholipase A2 Producing Bacteria and Pre-Term Labor

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to better understand (1) if phospholipase A2 producing microorganisms and cytokines (IL-1, IL-4, IL-6, IL-10, and IL-13) are associated with premature labor (2) if pregnant teens are more likely to have phospholipase A2 producing bacteria than a pregnant adults and (3) if there is a difference in the cytokines between pregnant teens and adults.We hypothesize that phospholipase producing microorganisms may trigger the onset of premature labor. The following are hypothesized: (a) The microorganism cultured should show high activities of phospholipase A2 (b) The cervical length measurement predictive value should correspond to the gestation age at term (c) Vaginal flora of teen will be more susceptible to colonization with higher phospholipase A2 producing bacteria than that of an adult (d) The maternal genotype contribution to the concentration of IL-1, IL-4, IL-6, IL-10, IL-13, and TNF-alpha during the first trimester of pregnancy in teens is different in the production of inflammatory cytokines and modulators(e) The maternal genotype of teens therefore influences the production of phospholipase A2 and causes an increase in preterm delivery.

Official Title
-----------------
Phospholipase A2 Producing Bacteria, Age at Gestation, Cervical Length Measurement and the Incidence of Pre-Term Labor

Conditions
-----------------
Preterm Labor

Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Gestational age <34 weeks Singleton gestation Urinalysis and urine culture collected via clean catch Age range 14 - 45 Patient receiving prenatal care at CAMC Women's Medicine Center Exclusion Criteria: In labor or with uterine contractions Known fetal anomalies Cerclage Dark amniotic fluid suggestive of previous bleeding Multiple gestation Known unbalance chromosomal complement Pregnant patient with prior history of excisional cervical biopsy (either cold knife, loop electrosurgical excision procedure, or laser conization) Patient with mullerian anomaly Patient with 2 or more D&E secondary to spontaneous or induced abortion

Ages Eligible for Study
-----------------
Minimum Age: 14 Years
Maximum Age: 45 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------
What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
Health Literacy Multi-media Study

Study Overview
=================
Brief Summary
-----------------
Cancer patients are presented with a lot of information about their diagnosis and different treatment options, which can be confusing. The purpose of this study is to see if a simple video explanation of six words used to describe cancer treatment improves patient understanding of these words.

Detailed Description
-----------------
Cancer patients are presented with a lot of information about their diagnosis and different treatment options, which can be confusing. The purpose of this study is to see if a simple video explanation of six words used to describe cancer treatment improves patient understanding of these words. Participants will be interviewed and asked the meaning of six words related to cancer treatment. Following the interview, participants will be shown a video about the meaning of the words. After viewing the video, participants will be re-interviewed to test how effective the video was at explaining the six words.

Official Title
-----------------
Improving Patient Understanding of Key Terms Used to Describe Chemotherapy and Its Side Effects

Conditions
-----------------
Cancer

Intervention / Treatment
-----------------
* Other: Educational Video


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Patients at Grady Memorial Hospital who is offered a consent to receive chemotherapy Exclusion Criteria: Profession as a physician or nurse Non English speaking
Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Other
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Education Group<br>Participants offered a consent for chemotherapy treatment will watch an educational video. | Other: Educational Video<br>* Participants will be asked if they know the meaning of six words related to cancer treatment. Following the interview, participants will watch a video explaining the meaning of the six words. After viewing the video, participants will be re-interviewed about the meaning of the six words.<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Number of Correct Responses | The number of correct responses to the meaning of the six cancer treatment words will be collected after watching the educational video. | Post Intervention (Up to ten minutes) | 
| Number of Incorrect Responses | The number of incorrect responses to the meaning of the six cancer treatment words will be collected after watching the educational video. | Post Intervention (Up to ten minutes) | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
Chemotherapy, Oncology
Observation of Rotation of an Intraocular Lens

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to assess the axial IOL rotation after surgery with an MC 6125 AS IOL. At the end of surgery the orientation of the IOL is documented with a short video clip via the operating microscope unit. Follow-up examinations are performed 1 hour, 1 week and 6 months after surgery. Rotational stability of the IOL is assessed using retroillumination images with a method to avoid bias from cyclorotation or head tilt.

Official Title
-----------------
Observation of Rotation of the MC 6125 AS Intraocular Lens

Conditions
-----------------
Cataract

Intervention / Treatment
-----------------
* Procedure: cataract surgery


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: Uni or bilateral age-related cataract necessitating phacoemulsification extraction and posterior IOL implantation Exclusion Criteria: Preceding ocular surgery or trauma Recurrent intraocular inflammation of unknown etiology Uncontrolled glaucoma Uncontrolled systemic or ocular disease Blind fellow eye Microphthalmus Corneal abnormality History of uveitis/iritis Iris neovascularization Pseudoexfoliation Proliferative diabetic retinopathy

Ages Eligible for Study
-----------------
Minimum Age: 40 Years
Maximum Age: 90 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| MC 6125 AS IOL<br>cataract surgery with implantation of intraocular lens MC 6125 AS in one eye | Procedure: cataract surgery<br>* cataract surgery with implantation of intraocular lens<br>|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| IOL rotation | The rotation of the IOLs over the first 6 postoperative months | 6 months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
IOL rotation
A Comparison of Seroquel vs. Risperidone in Schizophrenia

Study Overview
=================
Brief Summary
-----------------
The purpose of this study is to show equal efficacy of both quetiapine and risperidone in subjects treated with study medication for up to 8 weeks.

Conditions
-----------------
Schizophrenia

Intervention / Treatment
-----------------
* Drug: quetiapine fumarate vs risperidone


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria Male / Female, 18-65 years old Schizophrenia (as per DSM IV) Exclusion Criteria Concurrent use of psychotropic medication Does not fulfill moderately ill on CGI

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 65 Years

Sexes Eligible for Study
-----------------
All

Accepts Healthy Volunteers
-----------------
No

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Treatment


Arms and Interventions

| Intervention/Treatment |
| --- |
|Drug: quetiapine fumarate vs risperidone|nan|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
Insitu Repair Versus Uterine Exeriorization During Cesarean Section

Study Overview
=================
Brief Summary
-----------------
Two types of uterine repair described during cesarean section, the investigators will try to compare between the two techniques.

Detailed Description
-----------------
Insitu repair of the uterus during cesarean section in Comparison to exteriorisation of the uterus during uterine closure

Official Title
-----------------
Insitu Repair Versus Uterine Exeriorization During Cesarean Section: A Randomised Controlled Trial

Conditions
-----------------
Complications; Cesarean Section

Intervention / Treatment
-----------------
* Procedure: insitu repair
* Procedure: exteriorisation of the uterus


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: pregnant women Exclusion Criteria: liver disease kidney disease bleeding tendency abnormal placentation preeclampsia

Ages Eligible for Study
-----------------
Minimum Age: 18 Years
Maximum Age: 42 Years

Sexes Eligible for Study
-----------------
Female

Accepts Healthy Volunteers
-----------------
Accepts Healthy Volunteers

Study Plan
=================
How is the study designed?
-----------------

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: insitu repair<br>insitu repair of the uterine incision during caeserean section | Procedure: insitu repair<br>* closure of the uterine incision while the uterus initu<br>* Other names: repair insitu;|
| Active Comparator: exteriorisation of the uretus<br>uterine closure during caeserian section with exteriorisation of the uterus | Procedure: exteriorisation of the uterus<br>* uterine closure while the uterus is exteriorised<br>* Other names: uterine closure with exteriorisation of the uterus;|

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Bowel movement | Regain of bowel movement | 12 hours | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Surgery duration | The duration of intraoperative surgey | 2 hours | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
insitu repair, intestinal motility