Short-term and Oncological Outcomes of Laparoscopic Colorectal Cancer Surgery in Obese Patients

Study Overview
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Brief Summary
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A total of 138 consecutive patients who underwent laparoscopic-assisted or open colectomy for colorectal cancer (CRC) were included in the present study. Subjects commonly shared a condition of overweight or obesity. The investigators aimed to define any difference between the two different groups (open vs laparoscopic-assisted surgery) and a series of outcomes, i.e. hospitalization, Lymph nodes number, Intra-Surgery complications, and Clavien Dindo score.

Detailed Description
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A total of 138 consecutive patients who underwent laparoscopic-assisted or open colectomy for colorectal cancer (CRC) were included in the present study. Intra-Surgery complications, Previous surgery, Readmission Post Intervention, Location of surgery, Duration of Surgery, Re-intervention (yes), Clearance, and CRM were collected. Subjects commonly shared overweight or obesity. The investigators aimed to define any difference between the two different groups (open vs laparoscopic-assisted surgery) and a series of outcomes, i.e. hospitalization, Lymph nodes number, Intra-Surgery complications, and Clavien Dindo score.

Official Title
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Short-term and Oncological Outcomes of Laparoscopic Colorectal Cancer Surgery in Obese Patients

Conditions
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Obesity, Colorectal Cancer

Intervention / Treatment
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* Procedure: Open or Laparoscopic-assisted Colorectal surgery


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Body mass index >25 Kg/m2 Colorectal cancer (CRC) Exclusion Criteria: Current emergency conditions (i.e., perforation and\or occlusion) Pregnancy, Co-existing peritoneal carcinomatosis Contraindications to LS, such as cardiorespiratory comorbidities (CHD, CHF, and other severe CVD) Prior transverse resections

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 90 Years

Sexes Eligible for Study
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All

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| subjects who underwent open-air surgery<br>Fifty-one (37%) out of 138 subjects underwent open-air surgery. | Procedure: Open or Laparoscopic-assisted Colorectal surgery<br>* Colorectal surgery<br>|
| subjects underwent laparoscopic-assisted surgery<br>A total of 87 (63%) out of 138 subjects underwent laparoscopic-assisted surgery. | Procedure: Open or Laparoscopic-assisted Colorectal surgery<br>* Colorectal surgery<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Hospitalization | days | baseline | 
| Lymph Nodes number | Lymph Nodes number | baseline | 
| Clavien Dindo score (post-operative complications) | 1 to 5 point | baseline | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Age | years | Baseline | 
| Body mass index | Kilograms/m2 | Baseline | 
| Lenght of specimen | centimeters | Baseline |