Morbidity Rate for UTI Through Use of PCR-Based Diagnosis and Management

Study Overview
=================
Brief Summary
-----------------
This retrospective study is to determine if the use of PCR for detection and identification of pathogens in UTI along with antimicrobial susceptibility information, affords more efficacious treatment of UTI, as compared to traditional urine culture for patients served by House Call Physicians.

Detailed Description
-----------------
The objective of this study is to determine if retrospective data will show that use of PCR for detection and identification of pathogens in UTI, and antimicrobial susceptibility information, affords more efficacious treatment of UTI, thereby reducing UTI-related morbidity and costs in a patient population that is served by House Call Physicians. House call physicians attend elderly and other adults patients who are suffering from illness or chronic conditions in the safety, privacy, and comfort of their home or assisted living location. In making house calls, physicians ease the burden and difficulty of these chronic patients from traveling to the doctor's office.

Official Title
-----------------
Reduction in Morbidity Rate for Urinary Tract Infections Through Use of PCR-Based Diagnosis and Management

Conditions
-----------------
Urinary Tract Infections

Intervention / Treatment
-----------------
* Diagnostic Test: Guidance UTI


Participation Criteria
=================
Eligibility Criteria
-----------------
Inclusion Criteria: All patients that the House Call Physician suspects the patient has a UTI and are tagged with the following codes within the medical record Exclusion Criteria: Records where the NPI does not match a known provider or the office listed is not a Specific Population Hospice patients Records for which DX codes of X and NoDx where there isn't a diagnostic description.

Study Plan
=================
How is the study designed?
-----------------

Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Traditional Urine Culture<br>Patients treated based upon traditional urine culture | |
| Guidance PCR/Pooled Sensitivity<br>Patients treated based upon multiplex UTI PCR/pooled sensitivity results | Diagnostic Test: Guidance UTI<br> <br> |

What is the study measuring?
-----------------
Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| ER Visits and or Hospital Admission Rate within 30 days of initial visit related to UTI | Examine retrospective data of a House Call Patient population to determine if use of PCR, compared with conventional urine culture, leads to a reduction in UTI-related morbidity, as measured by the composite variable number of emergency room/urgent care clinic visits plus the number of admissions to hospital within 30 days of an initial presentation for UTI. | 18 Months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Examine retrospective data to determine if use of PCR, compared with conventional urine culture, leads to a reduction in UTI-related morbidity. | Examine retrospective data to determine if use of PCR, compared with conventional urine culture, leads to a reduction in UTI-related morbidity: As measured by the number of emergency room visits within 30 days of an initial presentation for UTI. As measured by the number of urgent care clinic visits within 30 days of an initial presentation for UTI. As measured by the number of cases escalated from an urgent care clinic to an emergency room within 30 days of an initial presentation for UTI. As measured by the number of admissions to hospital within 30 days of initial presentation for UTI. As measured by the total hospital length of stay resulting from hospital admission within 30 days of initial presentation for UTI. | 18 Months | 

 Terms related to the study
=================
Keywords Provided by Centre Hospitalier Valida
-----------------
UTI, Home Care