Resistance Training as an Aid to Smoking Cessation Treatment

Study Overview
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Brief Summary
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The purpose of this study is to determine whether resistance training can aid smoking cessation.

Official Title
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Resistance Training as an Aid to Smoking Cessation Treatment

Conditions
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Cigarette Smoking

Intervention / Treatment
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* Behavioral: Resistance training
* Behavioral: Health and Wellness


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Age 18 or older, smoke five or more cigarettes a day for at least the past 12 months Exclusion Criteria: Participating in any type of exercise for >60 minutes/week over the past 3 months, current smokeless tobacco use, participation in an ongoing effort to quit smoking, current or planned pregnancy, any serious medical condition that would make exercise unsafe

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Resistance training<br>Participants will attend two, 45-60-minute progressive, moderate intensity resistance training sessions per week for 12 weeks. The program will maintain a format of a 5-minute warm-up, 35-50 minutes of resistance training and a 5-minute cool-down with flexibility and abdominal exercises. | Behavioral: Resistance training<br> <br> |
| Active Comparator: Health and Wellness<br>Participants in this group will be required to attend the exact same number of sessions as those in the Resistance Training group. Each session will last approximately 45-60 minutes. Sessions will include a practical component/demonstration, an informational video, and a handout on a pertinent healthy lifestyle topic for adults. | Behavioral: Health and Wellness<br> <br> |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Smoking cessation | Salivary cotinine-verified 7-day Point Prevalence Abstinence (7-day PPA) from nicotine (cigarette smoking). | Change from baseline to 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Cortisol |  | 3, 6, 12 months | 
| Mood |  | 3, 6, 12 months | 
| Cigarette cravings |  | 3, 6, 12 months | 
| Abstinence self-efficacy |  | 3, 6, 12 months | 
| Sleep |  | 3, 6, 12 months | 
| Body composition |  | 3, 6, 12 months | 
| Body weight |  | 3, 6, 12 months | 
| Lung function |  | 3, 6, 12 months | 
| Blood pressure |  | 3, 6, 12 months | 
| Cholesterol profile |  | 3, 6, 12 months | 
| Glycosylated hemoglobin |  | 3, 6, 12 months | 
| Muscular strength |  | 3, 6, 12 months | 
| Aerobic fitness | Six-minute walk test | 3, 6, 12 months | 
| Smoking cessation | Salivary cotinine-verified 7-day Point Prevalence Abstinence (7-day PPA) from nicotine (cigarette smoking). | Change from baseline to 6 months | 
| Smoking cessation | Salivary cotinine-verified 7-day Point Prevalence Abstinence (7-day PPA) from nicotine (cigarette smoking). | Change from baseline to 12 months | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Smoking cessation, resistance training