Soy Fiber Improves Weight Loss and Lipid Profile

Study Overview
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Brief Summary
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The aim of this study is to examine the effects of soy fiber on body weight, body composition and blood lipids in overweight and obese participants.

Detailed Description
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Thirty nine overweight and obese college adults (19-39 y of age) were randomly assigned to consume control biscuits or biscuits supplemented with soy fiber for 12 wk (approximately 100g/d). Information on body weight, body mass index, waist/hip circumference, blood pressure as well as measures of lipoprotein, glucose concentrations, and HbA1c was obtained at baseline, 8 and 12 wk after intervention. Body composition was also assessed at baseline and wk 12, respectively.

Official Title
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Soy Fiber Improves Weight Loss And Lipid Profile In Overweight And Obese Adults: A Randomized Controlled Trial

Conditions
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Obesity, Overweight, Weight Loss

Intervention / Treatment
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* Dietary Supplement: biscuits supplemented with soy fiber


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: BMI of 23-35 kg/m2 Exclusion Criteria: Subjects taking any drugs, botanicals or nutraceutical known to influence body weight or blood pressure significant history of eating disorders strenuous exercise to lose weight lipid-lowering medication use of steroids and other agents that may influence lipid metabolism hyperlipidemia hyperglycemia diabetes mellitus cardiovascular disease major systemic diseases gastrointestinal problems liver and renal failure

Ages Eligible for Study
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Minimum Age: 19 Years
Maximum Age: 39 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Placebo Comparator: biscuits without soy fiber<br>biscuits without soy fiber | Dietary Supplement: biscuits supplemented with soy fiber<br>* Thirty nine overweight and obese college adults (19-39 y of age) were randomly assigned to consume control biscuits or biscuits supplemented with soy fiber for 12 wk (approximately 100g/d).<br>|
| Experimental: biscuits supplemented with soy fiber<br>biscuits supplemented with soy fiber | Dietary Supplement: biscuits supplemented with soy fiber<br>* Thirty nine overweight and obese college adults (19-39 y of age) were randomly assigned to consume control biscuits or biscuits supplemented with soy fiber for 12 wk (approximately 100g/d).<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| weight loss | Body weight of participants in soy fiber group was decreased significantly over the study period compared with the baseline. | 12 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| serum levels of total cholesterol | Serum levels of total cholesterol of participants in soy fiber group was decreased significantly over the study period compared with the baseline. | 12 weeks | 
| serum levels of low density lipoprotein cholesterol | Serum levels of low density lipoprotein cholesterol of participants in soy fiber group was decreased significantly over the study period compared with the baseline. | 12 weeks | 
| body fat | Body fat of participants in soy fiber group was lowered significantly at wk 12 than that of baseline. | 12 weeks |