Effect of Lumbrical Stretching on Carpal Tunnel Syndrome

Study Overview
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Brief Summary
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Symptoms of CTS occur when any condition decreases the size of the carpal canal or increases the volume of the structures within the carpal canal, compressing the median nerve. One cause of the symptoms of CTS is the incursion of the lumbrical muscles of the hand into the carpal canal. Individuals with CTS tend to have tight lumbrical muscles which increase this incursion, thereby increasing CTS symptoms. An intervention designed to reduce the incursion of the lumbrical muscles should have an effect on the symptoms of CTS. The purpose of this study is to systematically examine the effect of an intensive lumbrical muscle intervention, splinting to prevent lumbrical muscle incursion and lumbrical muscle exercises, on the symptoms of CTS. This project will be a randomized clinical trial to evaluate the effectiveness of a home program targeting the lumbrical muscles. One hundred and twenty subjects will be assigned to one of 4 groups: Group 1 will receive a home program of lumbrical muscle stretches combined with a lumbrical positioning splint; Group 2 will receive a home program of lumbrical muscle stretches combined with a night wrist cock-up splint; Group 3 will receive a home program of general stretches combined with a lumbrical positioning splint; and Group 4 will receive a home program of general stretches combined with a night wrist cock-up splint. After 1 month, 3 months, and 6 months the groups will be compared to determine if there is a significant reduction in symptoms between the groups.

Official Title
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Effect of Lumbrical Stretching on Carpal Tunnel Syndrome

Conditions
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Carpal Tunnel Syndrome

Intervention / Treatment
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* Other: Lumbrical splint and Lumbrical exercises


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: At least 18 yo Clinical symptoms of Carpal tunnel syndrome (CTS) Positive Tinel's, Phalen's, or Durkin's test Absence of thenar atrophy 2 pt discrimination of 5mm or less Exclusion Criteria: Persons needing immediate CTS surgery Pregnancy Compressive neuropathy in the ipsilateral arm Diabetes prior CTS release Non-English speaking

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: 1<br>Lumbrical splint and lumbrical stretches | Other: Lumbrical splint and Lumbrical exercises<br>* Subjects receive one of four possible interventions - Dose and Frequency are the same for each<br>|
| Active Comparator: 2<br>Lumbrical Splint and regular exercises | Other: Lumbrical splint and Lumbrical exercises<br>* Subjects receive one of four possible interventions - Dose and Frequency are the same for each<br>|
| Active Comparator: 3<br>Regular splint and lumbrical exercises | Other: Lumbrical splint and Lumbrical exercises<br>* Subjects receive one of four possible interventions - Dose and Frequency are the same for each<br>|
| Active Comparator: 4<br>Regular splint and regular exercises | Other: Lumbrical splint and Lumbrical exercises<br>* Subjects receive one of four possible interventions - Dose and Frequency are the same for each<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Carpal Tunnel Syndrome Symptom Severity and Functional Status Scale (CTS-SSFS) |  | 1 month | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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Carpal Tunnel Syndrome, Splint, Hand exercises