Collaborative Care for Depressed Elderly in Korea

Study Overview
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Brief Summary
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Late-life depression is associated with physical limitations, greater functional impairment, increased utilization and cost of health care, and suicide. Collaborative care, linking primary and mental health specialty care, has been shown to be effective for the treatment of late-life depression in primary care settings in Western countries. The primary aim of this project is to implement a depression care management intervention, and examine its effectiveness on the depressive symptoms of older patients in Korean primary care settings. Based on chronic disease management theory and previous Collaborative care management studies in western countries, we propose to test a Depression Care Management intervention,which includes care manager to support a primary care physician of depression in their old patients. Care manager'd role are monitoring the progress of treatment, supporting patient's adherence, educating patients/ family and facilitate communication between providers. Also psychiatrists provide consultation and supervision of care managers. Using a randomized controlled design, we will examine whether the Depression care management is an effective treatment for patients with late life depression in rural Korea. The primary outcome would be the improvement of depressive symptoms of patients in primary care setting.

Conditions
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Depression, Elderly, Korean, Collaborative Care

Intervention / Treatment
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* Other: care management


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 60 year or older diagnosed depression based on DSM-IV criteria Exclusion Criteria: impairment of hearing dementia other psychiatric disorders

Ages Eligible for Study
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Minimum Age: 60 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: case management<br>patients who assigned to the intervention group will take 7 times phone calls from case manager | Other: care management<br>* patients who assigned to the intervention group will take 7 times phone calls from case manager<br>|
| No Intervention: control<br>usual care | |

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Reduced depression symptoms | HAMD (Hamilton Depression Ratind Scale) Difference HAMD score between the intervention and control group from baseline to 3 month follow-up | 3 months | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Depression response and remissionhealth related quality of life | HAMD (Hamilton Depression Ratind Scale) Depression response is defined by improvement 50% or more HAMD scores from baseline to each follow-up periods. Depression remission is defined by 7 or less of HAMD score at each follow-up periods | 3months and 6months | 
| Reduced suicide ideation | SSI (Beck's suicide ieation scale) Difference total SSI scores Between the two groups from baseline to each follow-up periods | 3 months and 6 months | 
| Improvement of Quality of life | EQ5D Difference EQ5D scores Between the two groups from baseline to each follow-up periods | 3 months and 6 months |