Pulmonary Rehabilitation in Asthma Control

Study Overview
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Brief Summary
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The investigators compared the effectiveness of pulmonary rehabilitation program on asthma control in patients with uncontrolled and partially controlled asthma.

Detailed Description
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Asthma treatment is not only medical, it also requires a comprehensive care including nonpharmacological treatment. Pulmonary rehabilitation represents the most important part of the comprehensive care. The investigators aimed to evaluate the efficacy of pulmonary rehabilitation in patients with uncontrolled and partially controlled asthma. Asthma patients referred to pulmonary rehabilitation (PR) unit were classified according to asthma control test; as partially controlled patients (Group 1), and as uncontrolled patients (Group 2). All patients received of a 8 week pulmonary rehabilitation program. Asthma control tests, pulmonary function tests, arterial blood gases analysis, dyspnea perception, quality of life, exercise capacity, anxiety and depression assessments were performed before and after pulmonary rehabilitation.

Official Title
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Does Pulmonary Rehabilitation Contribute to Asthma Control?

Conditions
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Asthma

Intervention / Treatment
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* Other: Exercise


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Asthmatic patients referred from the outpatient clinic to Pulmonary Rehabilitation unit was confirmed according to GINA guidelines Exclusion Criteria: If the initial diagnosis cannot be confirmed, the patient excluded from the study Patients were under medical treatment of -6 months and considered clinically stable. Patients with cardiovascular, other lung diseases (pneumoconiosis, pulmonary tuberculosis, interstitial lung disease), or musculoskeletal diseases that would impair exercise training were excluded from the study. Also subjects with lack of motivation, poor compliance (not attending the program more than 2 times) or having transport problems were excluded from the study
Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Supportive Care
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Other: patients with uncontrolled asthma.<br>8 week pulmonary rehabilitation program | Other: Exercise<br>* 8 week exercise program including breathing exercises consisted of pursed-lip breathing, diaphragmatic breathing and thoracic expansion exercises, relaxation and stretching exercises, upper and lower extremity muscle strength training, and aerobic exercises. In addition, bronchial hygiene techniques and dyspnea-reducing positions<br>|
| Other: patients with partially controlled asthma<br>8 week pulmonary rehabilitation program | Other: Exercise<br>* 8 week exercise program including breathing exercises consisted of pursed-lip breathing, diaphragmatic breathing and thoracic expansion exercises, relaxation and stretching exercises, upper and lower extremity muscle strength training, and aerobic exercises. In addition, bronchial hygiene techniques and dyspnea-reducing positions<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Asthma control test score | A test measured the control of asthma | 4 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Exercise capacity | Six minute walk test | 6 minute | 
| Dyspnea | MMRC Dyspnea Scale | 1 year | 
| Quality of Life | St. George Respiratory Questionnaire | 1 year | 
| Pulmonary Function Test | FEV1, FVC, DLCO | 1 hour | 
| Arterial Blood Gas | PaO2, PaCO2, SaO2 | 1 hour | 
| Anxiety and Depression | Hospital Anxiety and Depression Scale | 1 week | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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asthma control, pulmonary rehabilitation