Comparison of Perioperative Analgesic Efficacy of Femoral Nerve Block, Adductor Canal Block and 4in1 Block

Study Overview
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Brief Summary
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Central neuraxial and regional anesthesia and analgesia techniques significantly reduce perioperative morbidity and mortality in the knee and below-knee surgeries.Nerve blocks appear to have better analgesic efficacy compared to placebo or patient-controlled analgesia (PCA). In addition, opioid-related side effects such as postoperative nausea, vomiting, pruritus, sedation, and respiratory depression are less. Therefore, interest in regional blocks such as femoral, sciatic, adductor, combined femoral, and sciatic is increasing. The knee joint is innervated by various nerves (genicular nerves) from the femoral, obturator, and sciatic nerves, and a comprehensive but simple technique is needed for postoperative analgesia. Complete and comprehensive postoperative analgesia was possible with this block, a simple single injection technique. The aim of our study is to evaluate the intraoperative analgesia efficacy of femoral, adductor canal block, and 4in1 block in patients who will undergo knee surgery.

Official Title
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Comparison of Perioperative Analgesic Efficacy in Patients Who Had Femoral Nerve Block, Adductor Canal Block and 4in1 Block Applied in Knee Surgery

Conditions
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Block, Analgesia

Intervention / Treatment
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* Other: femoral nerve block
* Other: adductor canal block
* Other: 4in1 block


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: Patients between the ages of >18 undergone knee surgery American Society of Anesthesiologists (ASA) classification I-III group. Exclusion Criteria: Patients who do not want to participate in the study coagulopathy peripheral neuropathy local anesthetic drug allergy chronic opioid users anticoagulant users pregnant patients

Ages Eligible for Study
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Minimum Age: 18 Years
Maximum Age: 99 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Other
Allocation: Randomized
Intervention Model: Parallel Assignment
Interventional Model Description: Group I: Femoral nerve block Group II: Adductor canal block Group III: 4in1 block
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: femoral nerve block<br>To evaluate the intraoperative analgesia effectiveness of femoral nerve block in patients who will have knee surgery. | Other: femoral nerve block<br>* To evaluate the intraoperative analgesia effectiveness of femoral block in patients who will have knee surgery.<br>|
| Experimental: adductor canal block<br>To evaluate the intraoperative analgesia effectiveness of adductor canal block in patients who will have knee surgery. | Other: adductor canal block<br>* To evaluate the intraoperative analgesia effectiveness of adductor canal block in patients who will have knee surgery.<br>|
| Experimental: 4in1 block<br>To evaluate the intraoperative analgesia effectiveness of 4in1 block in patients who will have knee surgery. | Other: 4in1 block<br>* To evaluate the intraoperative analgesia effectiveness of 4in1 block in patients who will have knee surgery.<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| intraoperative analgesia efficacy | The aim of our study is to evaluate the intraoperative analgesia efficacy of femoral, adductor canal block and 4in1 block in patients who will undergo knee surgery. | perioperative period | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| postoperative analgesia efficacy | The aim of our study is to evaluate the postoperative analgesia efficacy of femoral, adductor canal block and 4in1 block in patients who will undergo knee surgery. | perioperative period | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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4 in 1 block, femoral block, adductor canal block