Short-term Outcomes of ERAS Protocol in RAME for Esophageal Cancer

Study Overview
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Brief Summary
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This single-center, retrospective cohort study aimed to evaluate the short-term outcomes of enhanced recovery after surgery (ERAS) protocol in perioperative robotic-assisted McKeown esophagectomy (RAME) among esophageal cancer patients.

Official Title
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Short-term Outcomes of Enhanced Recovery After Surgery Protocol in Robotic-assisted McKeown Esophagectomy for Esophageal Cancer

Conditions
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Esophageal Cancer Patients

Intervention / Treatment
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* Procedure: ERAS protocol


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: first detected and endoscopically confirmed esophageal cancer; preoperative evaluation showed no distant metastases and suitable for RAME; preoperative clinical stage of I to III; Exclusion Criteria: patients had a history of thoracic or abdominal surgery; patients were IV to VI in the American Society of Anesthesiologists (ASA) physical status classification system; patients had other malignancies; patients had missing clinical data

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 80 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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No

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| ERAS group<br> | Procedure: ERAS protocol<br>* Patients with esophageal cancer have undergone RAME using ERAS protocol and conventional management strategy<br>|
| Conventional group<br> | Procedure: ERAS protocol<br>* Patients with esophageal cancer have undergone RAME using ERAS protocol and conventional management strategy<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| time to first flatus | time to first flatus characterized by postoperative outcome | 2019-2022 | 
| time to out-of-bed activity | time to out-of-bed activity characterized by postoperative outcome | 2019-2022 | 
| time to liquid diet | time to liquid diet characterized by postoperative outcome | 2019-2022 | 
| postoperative pain score | postoperative pain score characterized by postoperative outcome and was scored according to the numeric pain rating scale (NPRS) to assess the patient's pain on the first day after surgery. | 2019-2022 | 
| duration of analgesic pump | duration of analgesic pump characterized by postoperative outcome | 2019-2022 | 
| postoperative hospital stay | postoperative hospital stay characterized by postoperative outcome | 2019-2022 | 
| ICU length of stay | ICU length of stay characterized by postoperative outcome | 2019-2022 | 
| in-hospital mortality | in-hospital mortality characterized by postoperative outcome | 2019-2022 | 
| incidence of various postoperative complications | incidence of various postoperative complications characterized by postoperative outcome | 2019-2022 | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| postoperative chest drainage volume | postoperative chest drainage volume characterized by postoperative outcome | 2019-2022 | 
| preoperative anesthesia time | preoperative anesthesia time characterized by intraoperative outcome | 2019-2022 | 
| operation time | operation time characterized by intraoperative outcome | 2019-2022 | 
| blood loss | blood loss characterized by intraoperative outcome | 2019-2022 | 
| conversion rate | conversion rate characterized by intraoperative outcome | 2019-2022 | 
| radicality of surgery | R0 resection was defined as > 1mm from all resection margins, R1 resection was defined as microscopic residual tumor, and R2 resection was defined as macroscopic residual tumor | 2019-2022 |