The Impact of Migraine on Canadians' Productivity: A Real-World Pharmacy-Based Study

Study Overview
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Brief Summary
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This is a cross-sectional, real-world observational, community pharmacy-based study in which adults treated with a triptan for their migraine will self-report productivity and activity impairment using a web-based portal or paper-based questionnaire.

Detailed Description
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The primary objective of this study is to estimate the productivity and activity impairment associated with migraine in adults treated with a triptan. Participant identification will be made using pharmacies member of the PROxy Network. Eligible participants will be identified using the prescription of any formulation of triptans either when filling or refilling a prescription of a triptan or in the pharmacy electronic database (patients with a renewal in the last 3 months). The PROxy Network is a research network bringing together community pharmacies across Quebec to facilitate the generation of real-world evidence. This network is designed to better understand a disease or a treatment using patient-reported outcomes (PROs). The PROxy Network is an initiative of PeriPharm Inc., a company specializing in pharmacoeconomics and outcomes research.

Official Title
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The Impact of Migraine on Canadians' Productivity: A Real-World Pharmacy-Based Study

Conditions
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Migraine

Intervention / Treatment
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* Drug: observational study


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: 18 years of age or older; New or current prescription (renewal in the last 3 months) of any formulation of triptans medication (i.e., almotriptan, eletriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan and frovatriptan); Working full or part-time or going to school full or part-time; Ability to read and understand English or French; Signature of informed consent form (ICF). Exclusion Criteria: Patients participating in a clinical trial. Patients filling a one-time vacation/emergency prescription (i.e. without a complete pharmacy file).

Ages Eligible for Study
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Minimum Age: 18 Years

Sexes Eligible for Study
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All

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| No group<br> | Drug: observational study<br>* No intervention, observational study<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| The Migraine Disability Assessment (MIDAS) questionnaire | Patient-reported outcome: The Migraine Disability Assessment (MIDAS) is a 5-item, self-administered questionnaire designed to quantify headache-related disability over the past 3 months. The MIDAS is scored as the sum of five questions, each measured as days in the last 3 months, and then categorized into four disability grades with higher scores indicating greater disability: ''Grade I - Little to no disability'' for 0 to 5 days, ''Grade II - Mild disability'' for 6 to 10 days, ''Grade III - Moderate disability'' for 11 to 20 days and ''Grade IV - Severe disability'' for 21 days and over. | Baseline |