Effects of Ketogenic Diet in Body Builders

Study Overview
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Brief Summary
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the study sought to investigate the influence of 8 weeks of a very low carbohydrate ketogenic diet on body composition, muscle strength, muscle area and blood parameters in competitive natural body builders.

Detailed Description
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nineteen natural body builders were randomly assigned to a ketogenic diet (KD) group or to a normal diet group (ND) with a traditional meal pattern. The two diets were isocaloric and included the same amount of protein per kg of body weight; but differed in the distribution of fats and carbohydrates; the latter were kept below 5% daily (less than 50g/day) in the KD group while represented 55% of the caloric intake in the WD group During the experimental period, training loads were similar in the two groups. Athletes were tested before and after 8 weeks of the intervention. Body composition , basal metabolism, muscle strength and blood parameters were measured.

Official Title
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Effects of Two Months of Ketogenic Diet on Body Composition, Muscle Strength and Blood Parameters in Competitive Natural Body Builders

Conditions
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Diet, Healthy, Body Weight

Intervention / Treatment
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* Other: Ketogenic Diet
* Other: Normal Diet


Participation Criteria
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Eligibility Criteria
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Inclusion Criteria: at least 5 years of training experiences competing in recognized body building category Exclusion Criteria: adherence to special diets use of nutritional supplements (except a daily multivitamin-mineral and/or protein supplement) use of medications (steroids) diabetes or metabolic diseases

Ages Eligible for Study
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Minimum Age: 20 Years
Maximum Age: 40 Years

Sexes Eligible for Study
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Male

Accepts Healthy Volunteers
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Accepts Healthy Volunteers

Study Plan
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How is the study designed?
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Design Details

Primary Purpose: Basic Science
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single


Arms and Interventions

| Participant Group/Arm | Intervention/Treatment |
| --- | --- |
| Experimental: Ketogenic Diet<br>KD group consumed less than 50g/day of carbohydrates | Other: Ketogenic Diet<br>* KD group consumed less than 50g/day of carbohydrates<br>|
| Active Comparator: Normal Diet<br>ND group consumed 55% of the caloric intake from carbohydrates | Other: Normal Diet<br>* ND group consumed 55% of the caloric intake from carbohydrates<br>|

What is the study measuring?
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Primary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| Fat Mass | fat mass measured through body impedence analyser | 8 weeks | 
| Lean Body Mass | lean body mass mass measured through body impedence analyser | 8 weeks | 
| Maximal muscle strength | muscle strength measured via 1-RM test | 8 weeks | 

Secondary Outcome Measures

| Outcome Measure | Measure Description | Time Frame |
| --- | --- | --- |
| blood glucose | glucose as milligram per deciliter | 8 weeks | 
| testosterone | Testosterone free as picogram per milliliter | 8 weeks | 
| inflammatory cytokines | IL6, IL1β, TNFα measured as nanogram per deciliter | 8 weeks | 
| resting metabolism | resting energy expenditure measured as Kcal / day | 8 weeks | 

 Terms related to the study
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Keywords Provided by Centre Hospitalier Valida
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ketogenic diet, body builders, athletes, body composition, hormones