lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MATVSDTNSNNMPPAADSQPTTKQTVSSVVNTEPAGQPAPKREKRPAMPRTLGDILAPMTTQQFFDKHFERSFLYIPREDRDPGIVYQGLFSLDQLYTLLQRESMFYGTDLNLCRYDGERKLVLNGGRNDTTDLPTINGNHSNSQRAEEQDSNDSDDSDELAEEALAADVRRRVEDLKATVQFHQPQRFVRALHDLLYSFEQELTTLVGANVYITPANSQGLAPHHDDVEVYILQLEGEKAWRLYEPIEPLAMSYSADLDREELAQPIAELVLRPGDFLYLPRGTIHEASCVGNQHSTHITISSHQNWNYGHLMAQTLPECITNAMSNVLELRRGLPHGFLRQHGVLHAGFPPPPSAVFHHMRELLQSDQVWSEIERHFHQAVDSFALDYTTARLPPPALRRNPLNPAPTRVTPVFHATTKVRLVYTDHIRALPTPGAESNDDGQADDQPDFEIKVWHSLSNDVRTHMMQPALPDSEDEDDEHEEQDEEEEDTACSRSGLRESNDTGDVSSHDSSSATSSHLRSNPPLHPIGAVVPRDNPITLPGSAWPTLIHLMQLDGQGQRRTSAIQAIPGELQENILLCEQLWQKRLLVIEA
The following text describes a protein:
Function:
Zinc transporter. Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake (By similarity).
Miscellaneous:
MISCELLANEOUS: A role in zinc efflux has been proposed by Worlock et al, but ZntB was later shown in E.coli to likely mediate zinc uptake, using a transport mechanism that does not resemble the one proposed for homologous CorA channels.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Domain:
Forms a funnel-like structure. Contains three Zn(2+) binding sites, two of which could be involved in Zn(2+) transport.
Sequence:
MEAIKGSDVNVPDAVFAWLLDGRGGVKPLEDNDVIDSQHPCWLHLNYTHPDSARWLASTPLLPNNVRDALAGESSRPRVSRMGEGTLITLRCINGSTDERPDQLVAMRLYMDERFIVSTRQRKVLALDDVVSDLQEGTGPVDCGGWLVDVCDALTDHASEFIEELHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPWMSDDHRRRMQDIADRLGRGLDEIDACIARTGIMADEIAQVMQESLARRTYTMSLMAMVFLPSTFLTGLFGVNLGGIPGGGWRFGFSLFCILLVVLIGGVTLWLHRSKWL
The following text describes a protein:
Function:
Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC), and thereby plays a role in active DNA demethylation. Also mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC), and conversion of 5fC to 5-carboxylcytosine (5caC).
Domain:
Has good structural similarity to 2-oxoglutarate-dependent dioxygenases of the TET and the alkB families, in spite of very low overall sequence similarity.
Sequence:
MTTFKQQTIKEKETKRKYCIKGTTANLTQTHPNGPVCVNRGEEVANTTTLLDSGGGINKKSLLQNLLSKCKTTFQQSFTNANITLKDEKWLKNVRTAYFVCDHDGSVELAYLPNVLPKELVEEFTEKFESIQTGRKKDTGYSGILDNSMPFNYVTADLSQELGQYLSEIVNPQINYYISKLLTCVSSRTINYLVSLNDSYYALNNCLYPSTAFNSLKPSNDGHRIRKPHKDNLDITPSSLFYFGNFQNTEGYLELTDKNCKVFVQPGDVLFFKGNEYKHVVANITSGWRIGLVYFAHKGSKTKPYYEDTQKNSLKIHKETK
The following text describes a protein:
Function:
Galactose-specific lectin that displays calcium-dependent activity. Binds to the surface of hemocytes and enhances hemocyte encapsulation and melanization. This is likely by interacting with carbohydrates on the surface of the hemocytes. Also displays agglutination activity against the Gram-negative bacterium E.coli.
Subcellular Localization:
Secreted.
Sequence:
MLKTLVQLFLVVAGFAPGFGYDKYTTHIQNGNPYNLTVDMTPFIKINESYYVFGQTKVNWYVAYENCRRLQSELVTFETAEEFDAIAAFLNARGDRSEHWTSGNDLGKTGTHYWFSNAQLVTIKRWAPKQPDNAGGREHCIHLGYIYGYSTEFQLNDRPCHNHASSLFKYICEAPKQETVSIVVWK
The following text describes a protein:
Function:
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
Subcellular Localization:
Cytoplasm.
Sequence:
MIKIGLTGNFGMGKSTVAELFKKLGAYVISADKIVETLLEEPEVIEEIKKLFGNEVITNGKLNKKYISSIVFENPLMRIYLENILHPRVFEKVDEIVKNIPQRGEPIIVVVEAPIIFERGYQNKFDLIITVFTSEEIALERLEKKGISKEEAFRRLKCQFPIEMKKSKSDYIINNSGTLEETAQQVEAIFQKLIAMERKYAGN
The following text describes a protein:
Function:
Specifically methylates the N7 position of a guanine in 16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MNNANFEKYVDLVFEANKNFNLTGFKTKEAIYQNLVIEILTLFKGYEKFFIDKTVADLGSGNGSPGIILKLLFQKIKKLVLIDSKHKKISFLNKLTKQLNLEKTVAICERIEVHKNHYDVICSRGLSTIIKVNDLAFSLLNSKGIIFHIKQSLDQYIEFEKSNQKNQFNLLFIKHFTSQNKKLILIALQKND
The following text describes a protein:
Function:
Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages. Binds heparin.
Subcellular Localization:
Early endosome. Golgi apparatus, trans-Golgi network. Late endosome. Secreted.
Sequence:
MVKTSWLFLLLLVTLTGSKAENTRSGFWEYLSQLTSDKDKWDLQQNAAREINTLKSSFQNGVNYVGKFLGPLKNGFQQRLYQDTDGLQRLISRELQELRRKIYPYMDEAHQKISKNLEQLQSRLLPYTSELKDQVEWGAQELHLQLRPYKDDLKTWKMDKLAEHLQDRIILHTGRVKEGFYPLAERLVEEIHHAAEELHLNLSPHTHTTQDKLSQQVQELSQKLTKNARDLHEKIHKNLDELKQQLVSYPHQIKQQFPNGHSAEHVAPYVDEMAAQVQKEVEEFQRSTKMQIEDFTRTINKEAEEMQNKLSPASWDFQDSVSTVEDVQEKLDSLWRDIAQSLD
The following text describes a protein:
Function:
Thought to play a role in parasitophorous vacuole membrane function during the infection of host organisms.
Subcellular Localization:
Secreted. Parasitophorous vacuole membrane. Note=Localized to rhoptries which are secretory organelles at the apical end of the parasite and secreted during host cell invasion when it becomes associated with the parasitophorous vacuole membrane.
Sequence:
MGHPTSFGQPSCLVWLAAAFLVLGLCLVQQGAGRQRPHQWKSSEAALSVSPAGDIVDKYSRDSTEGENTVSEGEAEGSRGGSWLEQEGVELRSPSQDSQTGTSTASPTGFRRLLRRLRFWRRGSTRGSDDAAEVSRRTRVPLHTRLLQHLRRVARIIRHGVSAAAGRLFGRVRQVEAERPQPVFTEGDPPDLETNSLYYRDKVPGQGIIQEILRQKPGIAHHPESFSVVAADERVSRTLWAEGGVVRVASELGQPGRVLVRGRRIGLFRPGMQFEATDQATGEPMTALVGHTVLEATARDVDSMRNEGLAVGLFQKVKNPYLANRYLRFLAPFDLVTIPGKPLVQKAKSRNEVGWVKNLLFLLPPTHVDMETFVDEIGRFPQEDRPLADAARLYLTVQAVRLVAHLQDEGVVHGKIMPDSFCLKREGGLYLRDFGSLVRAGAKVVVPAEYDEYTPPEGRAAARSRFGSGATTMTYAFDAWTLGSVIFLIWCSRAPDTKSGYEYSVEFFFSRCRRVPENVKLLVYKLINPSVEARLLALQAIETPEYREMEEQLSAASRLYSGDGTLTGGDDDMPPLET
The following text describes a protein:
Function:
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
Subcellular Localization:
Nucleus.
Sequence:
MFGKVKHRHRVYFSARPLGQKTHEEETGGNVTSFIGDCARVCLSVHRRRGNMRTLGFCGDWLVTSCGTKLVAVHTKEDREAFVFDCSLAEKKPKQTKGDDTSEETGNDEVLAVATSASGKLLALTDDTKRLVLFGCEPSWRCISTRWVVRRCTALTFSRAEDELLLADKSGDVYSFSVVEAQRDGELKLGHLSMLLAVVISPDDRFIITADRDEKIRVSHRRSPYNIQAFCLGHRQFVSALHIPAGRPDWLLSGSGDGTVKLWEFESGRQLQSWELQQDVSAAEQNQNQVHPAADQDAAVCSVTSSPDAHHVAILCERDSSRHLFCLDSDGGTGFGPPHMLSLACSPLDVSFDQEGRLWVLMDSCEDPVQVLCCSQSGWQSLRGGSGGPELCRVMGGLKPHWSRSEASTRSFQHLFKVSYDNVTSYLQKKQQRLEEQLKRRAAQEEKSNKKSRGEESSPENPEEPENI
The following text describes a protein:
Function:
Dual transcriptional regulator of the TyrR regulon, which includes a number of genes coding for proteins involved in the biosynthesis or transport of the three aromatic amino acids, phenylalanine, tyrosine and tryptophan. These three aromatic amino acids act as effectors which bind to the TyrR protein to form an active regulatory protein. Acts by binding specifically to TyrR boxes in the promoter region of the target genes.
Subcellular Localization:
Cytoplasm.
Sequence:
MRLEVFCEDRLGLTRELLDLLVLRSIDLRGIEIDPIGRIYLNFAELEFTDFSSLMAEIRRISGVTDVRTVPWMPSEREHLALSALLEALPEPVLSLDMKSKVEMANPASCQLFAQSQERMRHHTAAQLINGFNFQRWLDGNPQSSHNEHVVINGQNFLMEITPVHLQNENDEYVLTGAVVMLRSTIRMGQQLQNLSTQDLSAFSQIIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPEDAVESELFGHAPEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVPRPKLSADLSTVLTRYGWPGNVRQLKNAIYRALTQLEGYELRPQDILLPDYDAATVAVGEDAMEGSLDDITSRFERSVLTQLYRSYPSTRKLAKRLGVSHTAIANKLREYGLSQKKGEE
The following text describes a protein:
Function:
Involved in the regulation of Pn.p cell fate determination. Involved in zinc metabolism and the decrease of the cytosolic zinc concentration which is thought to modulate Ras signaling. Involved in zinc transport from the intestinal lumen to the pseudocoelum.
Subcellular Localization:
Basolateral cell membrane; Multi-pass membrane protein.
Sequence:
MEVTMEDRSVKADKADRDDNNTTSTELLGKMRQTKVISTNQNNNHLIDRMVSIYEMEMIKSQSTETISDVSDVLEFTVIDNCSHGTHTLEHDLRLKGEPIGKSESVKGVSRSLIIQIGMTVIFCALEFITGVVCSSIAMLADSYHMAADVMALIVAFTCIKIATRPSTRLGYGWVRAETLGGFFNGIFMCTVCVLVFQEAVGRIINVHMITHPLQVLVIGFIGLLINLFGMFNLSGHGHSHGGGSHGHSHGGSHGHSHNNKKTKKNDGHGHSHANGHGHSHDGKSDCNGEEEPDHTRLNGKFRSASAMANSDANVRLLDNDDNSNDIIERRLSGVNSQNTIIATVDRQMTPYGTHMASEVLNVSSNNLDKSAQKTEQKKDKNVNIHGVWLHLLSDAFGSVIVMISAGFVYFLPTWKIAAYLDPILSISLASIMGFTAVVLVKTSGEKLLKQTPEGLDLEKVKKDLCSIVGVSKVEKLSVWTLCGQRIIAAAHVNICHPAVFPEAAYKIKNYFHDLGVHSTTIEPTFEDTCMQSMRIMVKKVVDGKSIEEPVSVSTENEITE
The following text describes a protein:
Function:
Regulator of the large subunit (LS) of RuBisCO. Involved either in the processing or in the stabilization of the processed transcript, probably by acting as a barrier to the 5'>3' degradation.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MEVTSTTFISTTRSSKYLTLTSYSPVILPASTLRRDFLGCCHSLRPSPHLRTRAGKRNSRRSSIRSPRLVVRASIDSGLILIVVAVTAFSAIAFAYCQSTFRKRKSSDEVATVHGGKNSAENRREIHGDIHEGNPVEINVGFRKVEEESVNLLEEEKAHQIHEVAVMDYDSVSAEDSQFAVASVTTVATAHTLIDESFSSSIVNGSVALESATFGVKTPEKQVGNSEDQKGLEHDFSQAVVGIHSIASPQVVDDTRALEYEYNGLLQKPLEYSIFAESKREEIHTFYGSNHSSAKSSRLPSLKAVSPAVTSATNSLFLDHKNNGVIDTQFPGQSSGQATGDVQEENLVAHSNGGVSHIRKDVKGDWKFPSDGKHVGHQIDESMPQFPARNFELHNSNGRSPETSDAYNRLLRDGRIKDCISLLEDLDQRDLLDMDKIYHASFFKACKKQRAVKEAFRFTKLILNPTMSTFNMLMSVCASSQDIEGARGVLRLVQESGMTADCKLYTTLISSCAKSGKVDAMFEVFHQMSNSGVEANLHTFGALIDGCARAGQVAKAFGAYGILRSKNVKPDRVVFNALISACGQSGAVDRAFDVLAEMKAETHPIDPDHISIGALMKACCNAGQVERAKEVYQMIHKYGIRGTPEVYTIAVNSCSKSGDWDFACSIYKDMKEKDVTPDEVFFSALIDVAGHAKMLDEAFGILQDAKSQGIRLGTISYSSLMGACCNAKDWKKALELYEKIKSIKLRPTISTMNALITALCEGNQLPKAMEYLDEIKTLGLKPNTITYSMLMLASERKDDFEVSFKLLSQAKGDGVSPNLIMCRCITSLCKRRFEKACAGGEPVVSFKSGRPQIENKWTSMALMVYRETISGGTVPTTEVVSQVLGCLQLPHDAALRDRLISTLGINISSQKQHNIFPLVDGFGEYDPRAFSLLEEATSLGVLPSVSFNKIPLFFDTTELPKNVAEVYLLTIFKGLKHRLAAGAKIPHINLIISIQEKEIRTPEGEKTIDLTGRVGQEIGALLRRLDIPYHRKDSRLRINGVSLKNWFQPKLDSPFSGGKPGDLRSSQVPLGNQISRQQRSIRLGNLSLE
The following text describes a protein:
Function:
Guanine nucleotide-exchange factor (GEF) required for the formation or budding of transport vesicles from the ER.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MAPLIPSAKSTLSYPLYACDFDPIDSSRLVVGGGGGAGRTGVGNKITLLDTSNPNELVEAAEIDLSKEEDNVTSLAVGQPQGKTSLIYAGVNSSPEEFGKGNNAHFRVIGIEPVAKGKGKNTQPVATTSKLSEISRISLFTHVERDLYQRVIRLSRSYPGQSQWGAVATGLAKDSEVVLFKTARTGPPKSKGAIKLAKEAVDMDFIQTGKDDYLFAYADEYDIYVKKLGSMDDGAESECVYITPASRGKEKVTLPSFRSIRWLTKDFIVMLTNIHSQGGVVLQILRLPPSGKGQCRIAQSHRLPSSITKATGLAVSNLTPPVTPDEEQGYTQFVIAVAGHDISISLFKVDLQHELNNYLVTPIKPFRTFKNVHPLQITGITFSNFTPPTGPVTASTPPQYLKLASVGVSNTVIVHTLPLFPVPLSVKRGQSHTPRYVVALPSSKAIYSFGIILSMLVAVFAAIMMQSILEIRGVVEPHLGAANYLPIPLQEAIGKPYIFPSHYNALGTQASTSSIPPSSSDTSPSPSSPDFFASLRSPVPNSPPSRIYLHHGPPIPDIPAAVENQEKKITSPDTSPLIHAVLHDADKHTGKSWDELTAPQKESWKRKLKDAGHWVEGMGEAIFKGVVFGELRDLVGAAVVQAAAV
The following text describes a protein:
Function:
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MATGGGSYSFSLTTFSPSGKLVQIEHALAAVGQGTSSLGIKASNGVVIATEKKTASILVDDSIIEKVASICPNIGMVYSGMGPDYRVLVTRARKIAQSYWKIYGEYPPTRLLTQEIATVMQEATQSGGVRPFGVSLLIAGWDEHRGSTLYQVDPSGSFWPWKASAIGKNMVNAKTFLEKRYNDELSLEDAIHTAILTLKEGFEGQMTEKTIEIGVMGTVGVGADTVQPADRAQPVFRKLTEAEVKDFLAL
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Subcellular Localization:
Secreted.
Sequence:
MKMTRIFLSTLSLCLLLLQLNLSKAQPGSPQKLPFTFHSLFPFFGRPEDANIPLKGPQDDLQNVPQQAADQKPQKLSPDFYIKTCPNAQKIVADALADIVKKNPGALGNLLRLQFHDCFVNGCDASILLDYSPSGDTVEKSSMVNGLLLKGADMIDDIKLKLEEQCPQTVSCADTLAFTANEVMTMAGLPPRKPLGGRRDALVSLSSAADADNLPLPDWTMDQMVKLFTKKGFNIEEMVILLGAHSIGMAHCDLFIQRAYNFQNTGKPDPTLTVEAVEEFKKACPNVNTPKYRNPPVNFDATPTVLDNLFYMEMVERNRTFLITDSHLLTDQRTLPLVQQFAHDPSLFPRRFPEVMLKLGSLNVLTGNEGEIRKICRSTN
The following text describes a protein:
Function:
Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase.
Subcellular Localization:
Cytoplasm, cell cortex. Cytoplasm, cytoskeleton.
Sequence:
MTTESGSDSESKPEQEAEPQEAAGTQGPVGAPQGPGPEPSGEEQHQVLEQFEAAAHSTPVKKEVTDKEREFAAGAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGSEYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQIRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDYDPDECGNDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRASALIDRPAPYFERSSSKRYTMSRSLDGASVNENHEIYMKDSVSAAEVGTGQYATTKGISQTNLITTVTPEKKAEEERDEEEDRRKKAEEATPVAAARHEGKSPGLGTDSCPPSPPSAHRPPASSPELRRRCKENDCHPLGLEPAKGTVRVHGEPTLDSDHKGKPSLGDQDVAFSYKPQPGKGTTLFSFSLQLPESFPSLLDDDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPCFLFIFFFLLSASFSVPYALTLSFPLAMCLCYLEPKAASLSASLDNDPSDSSEEETDSERTDTAADGETTATESDQEEDAELKAQELDKTQDDLMKHQTNISELKRTFLETSTDTAITNEWEKRLSTSPVRLAARQEDAPMIEPLVPEEGTEDWVIVDKVPTEVVDGDSKKIVTYKVVTVSSRTSDIPADLLRSGAIEMQSFDDWAREMQLRGESKQKIYTLGKSYDTVSGKIVTMTGKAKEGEKGVPPCSPEAFQKAERGLAEPMKAFPPTADFEVLDAAPDEKPKRAPEVHTPKRKLSESLAPIREAESRRPSPEEEEDVQKAPGSGQATGPLAGLDSTRLARMEPAEGEVLKVGLFGPRRKSLSEWRYSQEPAVTVATAHYVTESATSRVVTKQSSSEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSWVQKTETKTESSKTETETSHLAPSPQPLSTEKEETAAASHEPEEEQSTTTHVPETREQKPHFESSTVKTESLSFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDAGADLEPGVLMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEITPEDGED
The following text describes a protein:
Function:
Aminotransferase that catalyzes the conversion of histidinol phosphate and 2-oxoglutarate into L-glutamate and imidazole acetol phosphate. Shows lower activity with aromatic amino acids.
Miscellaneous:
MISCELLANEOUS: Was identified as a high-confidence drug target.
Domain:
Hydrophilic residues in the substrate binding pocket and N-terminal lid allow the entry and binding of the preferential substrate, histidinol phosphate.
Sequence:
MTRSGHPVTLDDLPLRADLRGKAPYGAPQLAVPVRLNTNENPHPPTRALVDDVVRSVREAAIDLHRYPDRDAVALRADLAGYLTAQTGIQLGVENIWAANGSNEILQQLLQAFGGPGRSAIGFVPSYSMHPIISDGTHTEWIEASRANDFGLDVDVAVAAVVDRKPDVVFIASPNNPSGQSVSLPDLCKLLDVAPGIAIVDEAYGEFSSQPSAVSLVEEYPSKLVVTRTMSKAFAFAGGRLGYLIATPAVIDAMLLVRLPYHLSSVTQAAARAALRHSDDTLSSVAALIAERERVTTSLNDMGFRVIPSDANFVLFGEFADAPAAWRRYLEAGILIRDVGIPGYLRATTGLAEENDAFLRASARIATDLVPVTRSPVGAP
The following text describes a protein:
Function:
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to the erythrocyte membrane receptor SLC2A1/GLUT1 and may therefore provide a link between the spectrin cytoskeleton to the plasma membrane. Binds to calmodulin. Calmodulin binds preferentially to the beta subunit (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Domain:
Each subunit is comprised of three regions: a NH2-terminal protease-resistant globular head region, a short connecting subdomain, and a protease-sensitive tail region.
Sequence:
MSEDTVPEAASPPPSQGQHYFDRFSEDDPEYLRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPASSMNFSMMTPINDLHTADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVEKGSSCFPVDTTGFSLHSAIYAARPDVRCAIHLHTPATAAVSAMKCGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGMVALGDTVEEAFYKVFHLQAACEVQVSALSSAGGTENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSRLGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDGVPVPALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRNMGSPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLDMRNKIREQNRQDIKSAGPQSQLLASVIAEKSRSPSTESQLASKGDADTKDELEETVPNPFSQLTDQELEEYKKEVERKKLEQEQEGEKDAATEEPGSPVKSTPASPVQSPTRAGTKSPAVSPSKASEDAKKTEVSEANTEPEPEKPEGVVVNGKEEEPCVEEVLSKGPGQMTTNADTDGDSYKDKTESVTSGPLSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES
The following text describes a protein:
Function:
Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins.
Subcellular Localization:
Cytoplasm.
Sequence:
MPEEVHLGEKEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNTQEHTLTLVDTGIGMTKADLINNLGTIAKFQDQTEYLEEMQVKEVVEKHSQFLGYPITLYLEKEREKEISDGKAEEEKGEKEEENKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNTEDITQEEYGEFYKSLTNDWKDHLAVRYFSVEEYVSRMKEIQKSIYYITGESKEQVANSAFVEQVWKRDSRVVYMTEPIDGYQLKEFDGKSLVSVTKEGLELPEDGEEKKRMEERKAKFENLCKFMKETLDKKVEMVTVSNRLVSSSCCIVTSTYSWTANMEQIMKA
The following text describes a protein:
Function:
Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome. Binds to RNA (By similarity). Involved in pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MSHGPKGDINKQEWEDVEFPSICERCLGDNSYVRMTKEPLGQECKICSKPCTIFRWIKERGQKPGKTQICVGCARYKNCCQSCMLDLQFGLPIALRDAALKLVESGPTNDINREFFAQNQQRLLSNGETAYDSQEASAAARNLVKKVEKRELHSRPPKRKLDDVESKQILKEARASDASLNAERPLFPVKKIINGNVSLSINMEPPKDKKIASLFLIGVEDELADYKIRKHFEQYGPLKSVVCSHRAKCAFVNFKTRSSAEIAAAASPDGNVVIEGFRLKVQWGKPRSLGGPEGEVRNAKLADLVMRGSSHGNKTSQKSTIKNIENEDHENTKSPAVAIPIDPNQPRYRSQIPR
The following text describes a protein:
Function:
Involved in heme d1 biosynthesis. Catalyzes the introduction of a double bond into the propionate side chain of pyrrole ring D of dihydro-heme d1, therefore converting dihydro-heme d1 to heme d1.
Subcellular Localization:
Periplasm.
Domain:
Consists of an N-terminal domain that binds the heme c cofactor, followed by a long linker segment, and a C-terminal region that exhibits an eight-bladed heme d1-binding beta-propeller domain.
Sequence:
MRLIGLALGLLLGALAQAGEAPGEALYRQHCQACHGAGRLGGSGPTLLPESLSRLKPAQAREVILHGRPATQMAGFAGQLDDAAADALVAYLYQAPPREPQWSAEDIRASQVQPHPLATLPSRPRFEADPLNLFVVVESGDHHVTILDGDRFEPIARFPSRYALHGGPKFSPDGRLVYFASRDGWVTLYDLYNLKVVAEVRAGLNTRNLAVSDDGRWVLVGNYLPGNLVLLDARDLSLVQVIPAADAQGQASRVSAVYTAPPRHSFVVALKDVHELWELPYANGKPVAPKRLAVADYLDDFSFSPDYRYLLGSSRQARGGEVIELDSGARVASIPLSGMPHLGSGIYWKRDGRWVFATPNISRGVISVIDLQNWKPLKEIVTDGPGFFMRSHADSPYAWTDTFLGKKHDEILLIDKQTLEIAHRLRPSPGKVAGHVEFTRDGRYALLSVWDRDGALVVYDAHSLEEVKRLPMNKPSGKYNVGNKIGYAEGTSH
The following text describes a protein:
Function:
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.
Sequence:
MAKAPFNIQDQYLNQSRKERIKVAVRLMSGEKLEGYIKSFDNFSVLMEIQGDMLIYKHAITSITSVDGHFRLHQ
The following text describes a protein:
Function:
The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MNGLTAFLEKYFVPVAAKIGSQKHLVALRDAFISTMPITMAGSIAVLLNAFFRDFPTDWGWTGFVEAMQPLIGINGYVYNGTLAIVSIIFAFSLGYNLSKAYEVDRLAGGLVSLAAFVMNLTVTVSLDAVKAAIAASNANFDVATLPKEFAGIYGFFSLSQVNGTGLFTAMIFGFISTIIYAKLMRRNIIIKMPDSVPPAVSKAFAAIIPALVALYVVGIIDWAFFKITNMDVITWISKTIQEPLLSLSQGYGAVLLVTFLVQLLWFFGIHGPNVLAPVLESLWGTAQLQNISAAQEGAKLPFEWVRGSFDAYVWMGGSGGTLVLIIALLMFSKRADARTVAKLSLAPGIFNINEPIMFGLPIVLNTIYLIPFLIAPMVMVTIAYFATTLGIVGPVKIAVVWVMPPLLNSFLATGGDWMAPVISLINMVVAFLIWVPFVITANRVGVPEEEMKA
The following text describes a protein:
Function:
Positively regulates a late step in synaptic vesicle exocytosis.
Sequence:
MAAFLAKQMLGDQMKELQNITGGGKDEEGDGEKKELTEDGQDPEVAEALRQQEEARKEKHRKMEEEREKVRSTIRDKYGLKKKEKEQPQEDQQQEVDEDGVRSLTREKKPPPGIGEEEEEEEGPLDELWKMFSEKFPSIAEKFSNK
The following text describes a protein:
Function:
Controls stomatal patterning.
Subcellular Localization:
Secreted.
Sequence:
MKTTTPSSLTCLLLLLLFSLLFLITPPINAVRLHKVLTFSLFFFFFFLSSWNSACCSSRPWQKQSVVDRKRVAARAMIGSSPPRCINHNKRCSSCRHCEAVQVPVLPENKNGVDRYLFPKRINYRGESGDDGYDSNYKPMGWMCKCGDLLFIP
The following text describes a protein:
Function:
Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MHLLLFQLLVLLPLGKTTRHQDGRQNQSSLSPVLLPRNQRELPTGNHEEAEEKPDLFVAVPHLVATSPAGEGQRQREKMLSRFGRFWKKPEREMHPSRDSDSEPFPPGTQSLIQPIDGMKMEKSPLREEAKKFWHHFMFRKTPASQGVILPIKSHEVHWETCRTVPFSQTITHEGCEKVVVQNNLCFGKCGSVHFPGAAQHSHTSCSHCLPAKFTTMHLPLNCTELSSVIKVVMLVEECQCKVKTEHEDGHILHAGSQDSFIPGVSA
The following text describes a protein:
Function:
Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
Subcellular Localization:
Cytoplasm, perinuclear region.
Sequence:
MSQLSSTLKRYTESARYTDAPYAKSGYGTYTPSSYGANLAASFLEKEKLGFKPGPSTSFLTRPRTYGPPSILDYDRGRPLLRPDIIGGGKRAESQTRGTERPSGSGLSGGSGFPYGVTTSSLSYLPVNARDQGVTLTQKKSNSQSDLARDFSSLRTSDSYRLDPGNLGRSPMLARTRKELCALQGLYQAASRSEYLADYLENYGRKGSTPQVPTQAPLSRVPEVLSPTYRPSGRYTPWEKSKGQTPVSSRSSSPGRDTMNSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLSHSSSAHTALMEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTVRPKSSPEGLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRARKRCIKKFSVQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASENINHAVYNLYAVSNHSGTTMGGHYTAYCRSPVTGEWHTFNDSSVSPMSSSQVRTSDAYLLFYELASPPSRM
The following text describes a protein:
Function:
Carboxylesterase acting on esters with varying acyl chain length.
Sequence:
MATDSQPNQKLTLPLKTRIALTVISTMTDNAQRPDGTINRRFLRLFDFRAPPNPKPVNIVSTSDFVVDQSRDLWFRLYTPHVSGDKIPVVVFFHGGGFAFLSPNAYPYDNVCRRFARKLPAYVISVNYRLAPEHRYPAQYDDGFDALKYIEENHGSILPANADLSRCFFAGDSAGGNIAHNVAIRICREPRSSFTAVKLIGLISIQPFFGGEERTEAEKQLVGAPLVSPDRTDWCWKAMGLNRDHEAVNVGGPNAVDISGLDYPETMVVVAGFDPLKDWQRSYYEWLKLCGKKATLIEYPNMFHAFYIFPELPEAGQLIMRIKDFVDERVASLSA
The following text describes a protein:
Function:
Uptake of biotin. Acts probably by facilitated diffusion.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MALLIITTILWAFSFSFYGEYLAGHVDSYFAVLVRVGLAALVFLPFLRTRGNSLKTVGLYMLVGAMQLGVMYMLSFRAYLYLTVSELLLFTVLTPLYITLIYDIMSKRRLRWGYAFSALLAVIGAGIIRYDQVTDHFWTGLLLVQLSNITFAIGMVGYKRLMETRPMPQHNAFAWFYLGAFLVAVIAWFLLGNAQKMPQTTLQWGILVFLGVVASGIGYFMWNYGATQVDAGTLGIMNNMHVPAGLLVNLAIWHQQPHWPTFITGALVILASLWVHRKWVAPRSSQTADDRRRDCALSE
The following text describes a protein:
Function:
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Sequence:
FTTCVYSVMLRCCIRTAIMKSFYAVHIGKSPGVYDTWPECLAQVSKFKGAKYKKFSNKDEASYFAHTGTELSKDKSDILDIFKDELADNSAKESKPNNIPQSSIVSRKRKVKPDSNSRFGKVQKTNDQPTNATHVVYLVADSSDGSCPVVYTDGACSKNGRKGSRAGYGVWWGDDHKLNFSARLPGIPTNQRAEIAAVNKAIKQAIDVGHKQLLIRTDSKFVIDCITKWVQGWIRKGWVKADGKPVIHKVEFQEMLKNMKKINVKFEHVFGHRGNYGNEMADKLAVQGATMPYL
The following text describes a protein:
Function:
Component of the GSE complex, a GTPase complex required for intracellular sorting of GAP1 out of the endosome. Component of the EGO complex, a complex involved in the regulation of microautophagy.
Miscellaneous:
MISCELLANEOUS: Present with 3490 molecules/cell in log phase SD medium.
Subcellular Localization:
Vacuole membrane; Single-pass membrane protein.
Sequence:
MVMLHSKNVKGFLENTLKPYDLHSVDFKTSSLQSSMIITATNGGILSYATSNNDVPKNSINEINSVNNLKMMSLLIKDKWSEDENDTEEQHSNSCYPVEIDSFKTKIYTYEMEDLHTCVAQIPNSDLLLLFIAEGSFPYGLLVIKIERAMRELTDLFGYKLG