lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization.
Subcellular Localization:
Cell projection, cilium, flagellum membrane; Single-pass type I membrane protein. Note=Specifically located in the principal piece of sperm tail.
Sequence:
MPSAGQRKPGSLLALQALQKWLLRGGVGAMLARQVVAALLLWLSCCVSALWRYYINSQDYSIFSTRSSIKLEYEGNSFVSWKIPESCKVENTTSPKTTLHCKRAGIHTIKPIAGNQEVERHLTVDNSYICYLWYFTVVDVYYNLSQIVTIWVYDPESASTEELIWTAKKPSLSSRVLTKQMNTLGQRPFIFTVEKRLTYHPGPLTSEGTWVIHLPMSSDDIAKVIRGNKVAFQDCFIANLYFMLTYPMTIISEPPGYEPLTVPPGSPLMLSWDTCISTFALLATDQETFQTNDSFQTWTRVRAPPGILSDAQRHSLRDVIIFDQGTLFLVDGTVYLRTEDEFTKLDESRGISETGILGFSKRRWCQIRYLYKLASKKSILIAWSKTTVYAGYATFRFVTLTDTAKLKDFLKLPQTDTLEVMSVEYLWHPLEAAVLLSHCSVCTTNTRNIRIVIYSAIFQTWTLQDFELQLPKEAILEFRFLYSAMPDIIMWDQHHVYYSYKNFTVVGTISTPSGETNLSSLSQGSKIHQVLTDRIGNVVVKMENNVMFYIKADITEAVILHTWVNTTAKTVVLFDKSFEVCILYYNENLDEKYQLQTQPYPLILELQSINKDLGDWCPYLAFQHNIHSQFYHMDKGESLTIWSQIVYPENRGLYIVVEHYGSSVMTWTQNLEYEIASGFCTKTMITRFFQTTNYELVDNYYQLQKENTGLMLLQFRPSEFSRTCLTAKPVFEIDVGCDSSKYIMVRGFNKSRCQRRDFSYVIDKELLRESLSDNLKVRYDVAKYGCPLTLELGQMFQPIVELYDENGFIKIVDANFILWEIHGRNDYTFNSTMEQNGCINEAQTWDSMIEENPDIPLDDVWGPQNYRPCFSYAIGKPGDLGQPYEILNYSNKNHIKWPMTYAGMYVYRLKILDPNYSFCNLTTIFAIESLGMIPRSSVYLVAALIFVLMLTFISILVLSYFWYLKIYRQFIIEPLHKRPAKQKKN
The following text describes a protein:
Function:
In vitro, phosphorylates various substrates such as EmbR, PepE, MmaA4, Pyk, LldD and GroEL2.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MAHELSAGSVFAGYRIERMLGAGGMGTVYLARNPDLPRSEALKVLAAELSRDLDFRARFVREADVAAGLDHPNIVAVHQRGQFEGRLWIAMQFVDGGNAEDALRAATMTTARAVYVIGEVAKALDYAHQQGVIHRDIKPANFLLSRAAGGDERVLLSDFGIARALGDTGLTSTGSVLATLAYAAPEVLAGQGFDGRADLYSLGCALFRLLTGEAPFAAGAGAAVAVVAGHLHQPPPTVSDRVPGLSAAMDAVIATAMAKDPMRRFTSAGEFAHAAAAALYGGATDGWVPPSPAPHVISQGAVPGSPWWQHPVGSVTALATPPGHGWPPGLPPLPRRPRRYRRGVAAVAAVMVVAAAAVTAVTMTSHQPRTATPPSAAALSPTSSSTTPPQPPIVTRSRLPGLLPPLDDVKNFVGIQNLVAHEPMLQPQTPNGSINPAECWPAVGGGVPSAYDLGTVIGFYGLTIDEPPTGTAPNQVGQLIVAFRDAATAQRHLADLASIWRRCGGRTVTLFRSEWRRPVELSTSVPEVVDGITTMVLTAQGPVLRVREDHAIAAKNNVLVDVDIMTPDTSRGQQAVIGITNYILAKIPG
The following text describes a protein:
Function:
Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin to form chitosan and acetate. Chitosan is required to anchor melanin to the cell wall, for maintenance of cell wall integrity, and for proper cytokinesis. Chitosan offers an advantage during infection as it is less readily detected than chitin by host immunosurveillance mechanisms.
Subcellular Localization:
Secreted. Secreted, cell wall. Cell membrane; Lipid-anchor, GPI-anchor. Note=GPI-anchored cell membrane protein (GPI-PMP). Non-covalently associated to the cell wall independently of both its GPI-anchor and beta-1,6-glucan. Cell membrane localization is critical for effective deacetylase activity.
Sequence:
MIPSTAAALLTLTAGAAFAHTGCGGHEIGRRNVGGPMLYRRAVTDEASAAVSTDINTECTAYSYAPVTELISSFPTIWQTASIPSNDTEAQQLFGKINSTLNTKIPNDVPHGTPTGDWTGVNYSNSDPDCWWTHNKCTTPSNDTGLQADISIAPEPMTWGLGFDDGPNCSHNALYDLLLENNQKATMFFIGSNVLDWPLQAMRAHDEGHEICVHTWSHQYMTALSNEVVFAELYYTQKAIKAVLGVTPQCWRPPYGDVDNRVRMIAEGLNLTTIIWSDDTDDWAAGTNGVTEQDVTNNYQSVIDKAGNGTYTTHGPVVLNHELTNYTMSVFMTMFPKIKSAFNYIVPICTAYNITQPYAESNITCPNFETYISGVTNISSSTTQKDGSSSTNTASGSGAAGSASATSSSDDSSSSGGSSGSSGSNNASSGALGMFDSLSGVGLILGGVVAGVMLL
The following text describes a protein:
Function:
Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.
Sequence:
MAFSKTKASRLKCTDFSRKGEIDQFIISLVEIINNHDSYFTTSSCSGRIILFSESLDEYSVRKKGCRWLFVSHESASTADIISALDLEETKGEAVFKFEPFVLHVQCETTEHARKMHQAAVASGFRNSGITIGNGGKIMAAIRSTHGLEVPLTKEGRLLVSEDYIDFIVSLANSKMKENFNRIEKFQDTLQAMFREEKQNEADPNSRKNKHGRRLNERHPVKHKLTQTDTSDTEKDLDVSQSDVYENTKSFTNKECYSIDSRNTGDSESDCNVMTDLQGFAFLFKDSDEKT
The following text describes a protein:
Function:
Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Required for expression of cell cycle genes such as CYCD3-1, RNR2A and CDKB1-1. Promotes, in a dose- and auxin-dependent manner, organ growth by stimulating both cell proliferation and expansion, via the regulation of RBR1 levels.
Subcellular Localization:
Nucleus. Plastid, chloroplast membrane; Multi-pass membrane protein.
Sequence:
MTSILHSVSSILSSRVNSAERLGVLSLRNPVEFTRRRHGRSTSDFETSGRRLVVRAAETDTDKVKSQVPDKAPAGGGSSINQLLGIKGAAQETNKWKIRLQLTKPVTWPPLVWGVVCGAAASGNFHWTPEDVAKSILCMLMSGPCLTGYTQTINDWYDRDIDAINEPYRPIPSGAISEQEVITQVWVLLLGGLGIAGTLDVWAGHTTPTLFYLALGGSLLSYIYSAPPLKLKQNGWVGNFALGASYISLPWWAGQALFGTLTPDVVVLTLLYSIAGLGIAIVNDFKSVEGDRAMGLQSLPVAFGTEAAKWICVGAIDVTQLSVAGYLLASGKPYYALALLALIIPQIVFQFKYFLKDPVKYDVKYQRTAVLGAWHIRDGISIKSLNERIYDGVLATNVNPRELPEMSSDDERDEKELDLTSPEVVTKYKSAAEIVNKALQVVLAECKPKAKIVDICEKGDAFIKEQAGSMYKNAKKKIDRGVAFPTCVSVNNTVGHFSPLASDETVLEEGDMVKIDMGCHIDGFIALVAHTHVIQEGPVTGRKADVIAAANTAAEVALRLVRPGKKNHAVTEAIQKVAEAYDCKIVEGVISHQMKQNVIDASKSFLSVSTPETRVDDAEFEDNEVYAIDIVASTGEGKPKLIDEKQTTVYKKDAAVNYQLKMKASRFIISEIKEKFPHMPFTARSLEEKRARLGLVECVNHGHLQPYPVLYEKPGDFVAQIKFTVLLMPNGSDRITSHTLQELQPTKTIDDPEIKGWLALGIKKKKGGGKKKKAAKKAGETSTEAEPMEASSSAQE
The following text describes a protein:
Function:
Lipid-modulating phosphodiesterase. Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll-like receptor signaling. Has in vitro phosphodiesterase activity, but the physiological substrate is unknown. Lacks activity with phosphocholine-containing lipids, but can cleave CDP-choline, and can release phosphate from ATP and ADP (in vitro).
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor. Secreted.
Sequence:
MKSFFFLLLAGSVRLSSTERGYFWHLTDLHLDPNYTVTSDPRKVCPSAGDQLVTDAGQWGNYLCDSPRVLINSSIYAMKSILPKPDFILWTGDDTPHVPNEQLGEEAVLEIIKWLTNLIQQIFPTTKVYSALGNHDFHPKSQLPPHNNSIYYRISEFWSPWLKNESVISFQKGAYYSEELKDVGAAGRMIVLNTNLYYDSNSLTANMKDPGDQFQWLEEQLNNAYLKGEKVYIVGHVPPGYFEKKRDKPWFREEFNKRFIEIIQKHHGVIQGQFFGHHHTDSFKMFYSESGTPISSMFIAPGVTPWKTTLPGVENGANNPGIRVVEYDRQNLQVFDIVTYYLNLTYANKVSPRWEKEYRLTEAFQVPDCSAQSMHSVLRKIADDSCYLQKYYEYNSVSYDLEACNKSCRADHVCAIREVDFNKYKECIKTESSSIRHTFKIIVLFIAMSVYLFTFDL
The following text describes a protein:
Function:
Protein-lysine myristoyltransferase that catalyzes myristoylation of the protoxin (HlyA) at two internal lysine residues, thereby converting it to the active toxin.
Subcellular Localization:
Cytoplasm.
Sequence:
MNINKPLEILGHVSWLWASSPLHRNWPVSLFAINVLPAIQANQYVLLTRDDYPVAYCSWANLSLENEIKYLNDVTSLVAEDWTSGDRKWFIDWIAPFGDNGALYKYMRKKFPDELFRAIRVDPKTHVGKVSEFHGGKIDKQLANKIFKQYHHELITEVKRKSDFNFSLTG
The following text describes a protein:
Function:
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
Subcellular Localization:
Nucleus.
Sequence:
MHTLLFLSALGDPTTASEVGAEGVRRRVVFSEAHPPLLLTTIGTSGHTALSKEHAEALAVISGNMSSSSSALDVPLVEVICSYPTREGLCAECPALLLLVYEHVVAELQAGRRAVDVFRGTSRQDHLSELLAVRSLSELFERLYPLSQSCILDESTASSQFWRQARVTLEAAWAAPHDAKGRALLTQVRGQPRFHFCGPRDVETPGEGYPLHPVSLERALATSKRFLRTAMTCALDGSTDALAGRQPELRAVLQLAHLVPLTPSTGAPPRKEVTPEGLSFCMVSLQQRWWILVNAALERVLLLTRAAVNGNGNTSGSSGVTKPLLWQLLAVLSVLDTTQYVFAFPERQQDLAAHHLLARLSEVGLVYPLLSNDRKCFVLSPDFLHAIHWHASAPLSLTFNHHLLRSASGVSGAGIGDLRREDTDTIITETNFRLFAYTNDADLLNILNQFAELEEIVNGNLHCYRVTRASFAAAMRKGITAAQVLRFLSLRAHPSMLRRHGEREENGDTASPSSAGGASSSFTFSASPRRGAVAGTCGSTTSIDAVSTLVVPQSFCDQMRMWESECRRVVFEHHVVLLRNMSTQQQKAVTAYLTDAGEVDAVVHAERGYMVIREEVFERLVAPLLG
The following text describes a protein:
Function:
Involved in the MEC1-mediated checkpoint response to DNA damage and replication arrest.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MTMDQGLNPKQFFLDDVVLQDTLCSMSNRVNKSVKTGYLFPKDHVPSANIIAVERRGGLSDIGKNTSN
The following text describes a protein:
Function:
Cilium-specific protein required for the regulation of cilium/flagellum formation. Involved in centriole duplication (By similarity). May play a role in melanosome trafficking.
Subcellular Localization:
Chromosome, centromere. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasmic vesicle, secretory vesicle, acrosome.
Sequence:
MHTTRSPSASIQAGAAGDALDLSLNGSQLTMGRRPSSASPGKHFSRSISVSVAYDGRGKRNTLTDAGLGSSRAIKNLRRSNSTTQVNQQANTSLSSEGHTEDFLALFNSSSDGRRKLASLSKMSKDRTTWNILDDQPRVFPVPSSSHSTCSMDSPTGLKKREAGVSLAANFTANNRSNKAAVGNAVTAILHNNHSEKPLTPKSSNQKPSFNNLIKATVNDDVTLDVSGSLTKSQKNFSSASSSSNNNAPRSPRSPGQPRRREVTEEEAERYIQQVNHAAIIIQRWYRRHVNSKRANENIIKQLLASKKKEREQRAEEAKTTESLKKKEDDRKRIREEKARLARLTAIQELQQKRAQRAAEVQQIAEQETEALRHPGKVGRKKLTKSSPTSPTDIKAKNTDSNVNVVSDLDDVTNLRAASPAGSACRVSQCSQEILQRSVSMEDQRQGASSSRAQSKTTLNDLLDTLKLLEEEPERLSEPKSYRKDKYSWIDEDGDSNSLTTDNVERHRQLSQTPALPDGGALLSEAKLQSIMSFLDEMEKSEQERPRSVTSGSHREVVLSEEDLAVVEQASATAAEVTGSMMRLRLELDEKKRTVNMLQTALAQQRELTIRHVKETEKELNHTFQLQKEQYEATIQRHLTFIDQLIDDKKALSERCEEVVGELKQVDQKYTKKIAQMQEQHELVWQILGPMCEEIKKLKELMSATEKVRREKWINEKTKKIKEITVKGLEPEIQKLISKHKQELKKLRVLHEAELLQADERAAQRYVRQSEELRQQLEKEKDEQCQRERELAKQRFEKQLQEEENVLQQQRRRLYKEVSEEKERLTQLAARQHAELEDLRKQLEDNSSLAGRALREELEKSRDEQERRHQVEIKALKERLEIEKQTWEENYMKKEEAWLLSRERELKEEVRRGRDKEIELAIQRLEVETREAREECERAADNRMKRVREKYEAELRDLERSERTSLQKQQEMREKHSEMEAELLRLQSLLRQREQEISDLTQVTARDKLSEERRSLSEVIRQEFAERLIELEEENRRMKMEVSEAKARLRLEVERVTREKEEELAEVHQRVKSAILKKEETVNNLRKQHEAAVKRADHLESLLEQQRKQLLGK
The following text describes a protein:
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation. Involved in the control of endoreduplication.
Subcellular Localization:
Nucleus.
Sequence:
MEALGSSDCNLEILETLSDDAIQEITESYDGFFTTVESLIAGTGDSLVEDEFVSHVYCLCKYGLDSLVRDHFLRSLEQAFEKGGASSFWQHFDAYSEKKHHNYGEEIQIVLCKALEEISIEKQYHEKCLSIVVHALQSFKEQSSDDRQNSDTERVHLFSRFQSMLSSTLMTTLPQHFPEILHWYFKERLEELSAIMDGDGIEEQEDDCMDLDEKLRYKNGEMDVDEGCSQGKRLGHDKLVKNIGKVVRDLRSIGFTSMAENAYASAIFLLLKAKVHDLAGDDYRTSVLESIKEWIQTVPLQFLNALLSYLGDSVSYGTTSSGLTSPLACCPSPSFSRVVTPSEGIVRWKLRLEYFAYETLQDLRIAKLFEIIVDYPESSPAIEDLKQCLEYTGQHSKLVESFISSLKYRLLTAGASTNDILHQYVSTIKALRAIDPAGVFLEAVGEPIRDYLRGRKDTIKCIVTMLTDGSGGNANGSGNPGDSLLEELMRDEESQENVGFDDDFHTDDKQAWINASRWEPDPVEADPLKGSLSQRKVDILGMLVDIIGSKEQLVNEYRVMLAEKLLNKTDYDIDTEIRTVELLKIHFGEASMQRCEIMLNDLIDSKRVNTNIKKASQTGAELRENELSVDTLTSTILSTNFWPPIQDEPLELPGPVDKLLSDYANRYHEIKTPRKLLWKKNLGTVKLELQFEDRAMQFTVSPTHAAIIMQFQEKKSWTYKDLAEVIGIPIDALNRRVNFWISKGVLRESTGANSNSSVLTLVESITDSGKNEGEELLTGEEEGETSIASVEDQLRKEMTIYEKFIMGMLTNFGSMALERIHNTLKMFCVADPSYDKSLQQLQSFLSGLVSEEKLEFRDGMYLLKK
The following text describes a protein:
Function:
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
Subcellular Localization:
Cytoplasm. Cell membrane. Membrane raft.
Domain:
The SH3-binding motifs mediate interaction with SHC1 and GRB2; The PH domain mediates phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,4-bisphosphate binding.
Sequence:
MSGGGGDDVVCTGWLRKSPPEKKLRRYAWKKRWFILRSGRMSGDPDVLEYYKNEHSKKPLRIINLNLCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLVAETEADMNKWVQSICQICGFNQAEESTDSLRNLSSASHGPRSSPAEFSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSSHMQPTLSTSAPQEYLYLHQCISRRTENARSASFSQGTRQKSDTAVQKLAQSNGHCINGVGGQVHGFYSLPKPSRHNTEFKDSTYDLPRSLASHGHTKSSLTGSETDNEDVYTFKMPSNTLCRELGDLLVDNMDVPTTPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRPPKPSQAETSQWGSIQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPARGSGESASWSAEPPGKTAVGRSNSASSDDNYVPMNPGSSTLLAMERPGDNSQSVYIPMSPGPHHFDPLGYPSTALPIHRGPSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELPFKSPVTKSWSRINHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPGSPSPHRKPSTSSVTSDEKVDYVQVDKEKTQALQNTMQEWTDVRQSSEPSKGAKL
The following text describes a protein:
Function:
Involved in formation and maintenance of cell shape, probably part of the elongasome which synthesizes peripheral peptidoglycan (PG).
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Domain:
Deletion of the C-terminus (residues 183-272, CTD) suppresses activating mutations in khpB (also called eloR/jag); the deletion no longer interacts with MreD and interacts less efficiently with PBP1b and StkP, CTD deletion leads to increased phosphorylation of KhpB.
Sequence:
MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVDRVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLLDMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVEENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGDKVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS
The following text describes a protein:
Function:
Hydrolyzes acetyl esters in homogalacturonan regions of pectin. In type I primary cell wall, galacturonic acid residues of pectin can be acetylated at the O-2 and O-3 positions. Decreasing the degree of acetylation of pectin gels in vitro alters their physical properties.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MSICVVVFLGICLLSVQVESYDVNITYLESAVTTGAVCLDGSPLAYHFSAGFDRGVDNWLVFLEGGGWYDTPNSCLYRKNTCLDFFDWNKVKIRYCDGSSFTGDMEEVDPKTKLHYRGGRISEAVIDDLKEIGMKHAENVLLSGCSAGGLASILQCDHFRNIMPGRTNVKCLADAGYFINA
The following text describes a protein:
Function:
Involved in glucose repression of the SUC, GAL and MAL genes as well as of the CAT8 gene. Binds to two sites in the upstream region of SUC2.
Miscellaneous:
MISCELLANEOUS: Present with 830 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MQSPYPMTQVSNVDDGSLLKESKSKSKVAAKSEAPRPHACPICHRAFHRLEHQTRHMRIHTGEKPHACDFPGCVKRFSRSDELTRHRRIHTNSHPRGKRGRKKKVVGSPINSASSSATSIPDLNTANFSPPLPQQHLSPLIPIAIAPKENSSRSSTRKGRKTKFEIGESGGNDPYMVSSPKTMAKIPVSVKPPPSLALNNMNYQTSSASTALSSLSNSHSGSRLKLNALSSLQMMTPIASSAPRTVFIDGPEQKQLQQQQNSLSPRYSNTVILPRPRSLTDFQGLNNANPNNNGSLRAQTQSSVQLKRPSSVLSLNDLLVGQRNTNESDSDFTTGGEDEEDGLKDPSNSSIDNLEQDYLQEQSRKKSKTSTPTTMLSRSTSGTNLHTLGYVMNQNHLHFSSSSPDFQKELNNRLLNVQQQQQEQHTLLQSQNTSNQSQNQNQNQMMASSSSLSTTPLLLSPRVNMINTAISTQQTPISQSDSQVQELETLPPIRSLPLPFPHMD
The following text describes a protein:
Function:
Transforms 2,4-dichlorophenol (2,4-DCP) into 3,5-dichlorocatechol.
Sequence:
MALTIETDVLVVGTGPAGASAGALLARYGVRTMLINKYNWTAPTPRAHITNQRTMEILRDLGLEAEARLYAAPNDLMGENTICASLAGEEFGRIRTWGTDVRRRADYDECSPTSMCDLPQNYLEPILVKSAALDGCKVRFDTEYLGHEQDADGVSSRLRDRLNGEEFTVRSKYLIGADGANSRVVSDLDLPLEGTMGKSGSINLLFEADLDRYVAHRPSVLYWVIQPGSDIGGLGIGVVRMVRPWNKWLAIWGYDVEQGPPEISESFARRIVHNLIGDDSVPLKIEGISTWTVNDMYATRLQQGRVFCAGDAVHRHPPTNGLGSNTSIQDSFNLAWKIAMVLNGTADESLLDTYTIERAPIAKQVVCRANKSLEDFPPIAMALGLPQAKSADEMKSNMARRKEPGPEAQAQRTRLREAIAGTNYVYNAHGVEMNQRYDSPAIVADNSPDEVFRDVELYHQASTRPGAPMPHVWVYASGDGHRISTKDLCGKGNFTLFTGIGGAAWQDAAAAVSRQLGVAVTVRIIGPGQAYEDHYGDFARISEIIDTGAILVRPDFHVAYRATSLPADAAGDLVSAMRRILGRQSERSSALRVTSRAI
The following text describes a protein:
Function:
Probable iron-sulfur flavoprotein that converts 7-hydroxymethyl chlorophyll a to chlorophyll a using ferredoxin as a reducing equivalent. Catalyzes the reduction of a hydroxymethyl group to a methyl group.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MARCISFLSTSSSLPCATKPPCCSVSSVLPSSPSSHQCRGRKTSCGSIRALREDWRERSKAIPPGGVYPAKDHCSQCGLCDTYYIAHVKNACAFLGDGMSRVEDLEPLVHGRGRKQDMDEMYFGVYEQLLYARKMKPVEGAQWTGIVTTIAVEMLKANMVDAVVCVQSDPDDRLAPMPVLARTPDEVIAAKGVKPTLSPNLNTLALVEAAGVKRLLFCGVGCQVQALRSVEKYLGLEKLYVLGTNCVDNGTREGLDKFLKAASSEPETVLHYEFMQDYKVHLKHLDGHIEEVPYFCLPAKDLVDVIAPSCYSCFDYTNGLADLVVGYMGVPKYPGVSMTQHPQYITVRNDRGREMLSLVEGLLESTPTVSSGVRQPFVIETVKADDEAKQGRGPSQPAPTFVGNVIAFLLNLIGPKGLEFARYSLDYHTIRNYLHVNRAWGKQRAEQHIPSYAKKIVEAYDKDGRIESMLQ
The following text describes a protein:
Function:
Subtilisin-related protease involved in the formation of a protective dityrosine layer required for spore wall assembly. Identified in a screen for mutants with increased levels of rDNA transcription.
Subcellular Localization:
Spore wall.
Sequence:
MKPQCILISLLVNLAYAEEYLVRFKNPTAFQQFTSNSNRSWRQFIDNKIEKKFSIGSFRGVTMNLSKNLVNKLKKSPLVADIVPNFRFEAFEGDSVNSAESSYTFNATAKYSYEDVEEEQNITYQPDAPRHLARISRHYQLPFDVGDKDRYKSWFNYYYEHDYQGQDVNAYIMDTGIFADHPEFEDRVIQGIDLTKEGFGDQNGHGTHVAGLVGSKTYGAAKRVNLVEVKVLGKDGSGEASNVLSGLEFIVEHCTKVSRPQGKKCVANLSLGSFRSPIINMAVEGAIEEGIVFVAAAGNFNLDAYWASPASAENVITVGAFDDHIDTIAKFSNWGPCVNIFAPGVEIESLSHLNYNDTLILSGTSMSTPIVTGVAAILLSKGIEPEMIAQEIEYLSTRNVFHRRTLFFKPSTPNQILYNGVDKLDDPYDDETFPRLNIEAIAKELEEYNATLQTPMSENLQSGSKLWGWNNDVTLPLGEIRLKRRDFMKNL
The following text describes a protein:
Function:
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c (Probable). QCR10 has a role in CIII assembly and RIP1 stability.
Miscellaneous:
MISCELLANEOUS: Present with 5590 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MAYTSHLSSKTGLHFGRLSLRSLTAYAPNLMLWGGASMLGLFVFTEGWPKFQDTLYKKIPLLGPTLEDHTPPEDKPN
The following text describes a protein:
Function:
Functions in error-free postreplication DNA repair or DNA-damage tolerance (DTT) pathway. Required for homologous recombination (HR) induced by DNA double-strand break (DSB) in somatic cells. Required for damage-induced DNA repair, independently of MUS81 and RECQL4A. Plays a role in synthesis-dependent strand annealing (SDSA) but not in single-strand annealing (SSA). Possesses double-stranded DNA-dependent ATPase activity. Is able to regress replication forks with preference for forks with a leading strand gap. Is able to catalyze branch migration of Holliday junctions and is unaffected by protein blockades.
Subcellular Localization:
Nucleus.
Sequence:
MGTKVSDDLVSTVRSVVGSDYSDMDIIRALHMANHDPTAAINIIFDTPSFAKPDVATPTPSGSNGGKRVDSGLKGCTFGDSGSVGANHRVEEENESVNGGGEESVSGNEWWFVGCSELAGLSTCKGRKLKSGDELVFTFPHSKGLKPETTPGKRGFGRGRPALRGASDIVRFSTKDSGEIGRIPNEWARCLLPLVRDKKIRIEGSCKSAPEALSIMDTILLSVSVYINSSMFQKHSATSFKTASNTAEESMFHPLPNLFRLLGLIPFKKAEFTPEDFYSKKRPLSSKDGSAIPTSLLQLNKVKNMNQDANGDENEQCISDGDLDNIVGVGDSSGLKEMETPHTLLCELRPYQKQALHWMTQLEKGNCTDEAATMLHPCWEAYCLADKRELVVYLNSFTGDATIHFPSTLQMARGGILADAMGLGKTVMTISLLLAHSWKAASTGFLCPNYEGDKVISSSVDDLTSPPVKATKFLGFDKRLLEQKSVLQNGGNLIVCPMTLLGQWKTEIEMHAKPGSLSVYVHYGQSRPKDAKLLSQSDVVITTYGVLTSEFSQENSADHEGIYAVRWFRIVLDEAHTIKNSKSQISLAAAALVADRRWCLTGTPIQNNLEDLYSLLRFLRIEPWGTWAWWNKLVQKPFEEGDERGLKLVQSILKPIMLRRTKSSTDREGRPILVLPPADARVIYCELSESERDFYDALFKRSKVKFDQFVEQGKVLHNYASILELLLRLRQCCDHPFLVMSRGDTAEYSDLNKLSKRFLSGKSSGLEREGKDVPSEAFVQEVVEELRKGEQGECPICLEALEDAVLTPCAHRLCRECLLASWRNSTSGLCPVCRNTVSKQELITAPTESRFQVDVEKNWVESSKITALLEELEGLRSSGSKSILFSQWTAFLDLLQIPLSRNNFSFVRLDGTLSQQQREKVLKEFSEDGSILVLLMSLKAGGVGINLTAASNAFVMDPWWNPAVEEQAVMRIHRIGQTKEVKIRRFIVKGTVEERMEAVQARKQRMISGALTDQEVRSARIEELKMLFT
The following text describes a protein:
Function:
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides. It can degrade 3' or 5' ss regions extending from the termini of duplex DNA molecules and displaced ss regions. It can also excise thymine dimers in vitro (Probable). ssDNA-binding requires both subunits. Required for production of the mature 5'-end of retron Ec78 or Ec83 msDNA. Overproduction of this subunit in the absence of an equivalent quantity of the small subunit is toxic, causing cell elongation and chromosome fragmentation or loss; its toxicity is mostly suppressed by RecA.
Subcellular Localization:
Cytoplasm.
Domain:
Predicted to have 4 domains. The N-terminus (about residues 1-103) binds ssDNA and is required to bind the small subunit; it probably has an OB-fold. The predicted catalytic domain is residues 104-266. Three alpha-helices are predicted in the C-terminal region (residues 267-301, 307-349 and 353-393), their removal singly or in pairs reduces small subunit-binding; none of the deletions have exonuclease activity. The extreme C-terminus (394-456) is required for exonuclease activity. The N-terminus (residues 1-257) at low levels does not confer processing of msDNA and at higher levels is lethal. Lethality of this fragment is not counteracted by the small subunit.
Sequence:
MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAKLQAEGLFDQQYKKPLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYPAAVQGDDAPGQIVRAIELANQRNECDVLIVGRGGGSLEDLWSFNDERVARAIFTSRIPVVSAVGHETDVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTRQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLERLQKRMSFALENQLKRTGQQQQRLTQRLNQQNPQPKIHRAQTRIQQLEYRLAETLRAQLSATRERFGNAVTHLEAVSPLSTLARGYSVTTATDGNVLKKVKQVKAGEMLTTRLEDGWIESEVKNIQPVKKSRKKVH
The following text describes a protein:
Function:
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
Sequence:
MKPTVDYSLYLVTSSVIVPTGSTLEQQVEQAILGGVTLVQLREKNVSTKLFIERAEKVLQVCRKHNVPLLINDRVDVALAVGAEGVHIGQSDMDCATARRILGSDAVIGVTANNIQEIDKAEADGADYVGLGSVYDTATKNVKDRIIGIHGLRDLLEHISNMKRRLQTVAIAGLNASNVQRVIYLSEVNGVRVDGIALVSAIMASTEPKKAAEKLIQLIKTTPKFALPVSKLPKSDSTAFVSSIERVFSRAKSKTPLVQQLTNNVSKNFNANVTLAVGGSPLMCEFDDEFPELARANGALLCNYAAVDKLESYIFAAQCNNAENKPVILDPVGAGATEVRKRALTTMLDSAYFDYIKGNEGEILTLAGVEVQMRGVDSTSEFPLTEKVRVTKLLAEKRRCVVIMTGAVDVISDGNRTFVVKRGHPMLANITASGCAMGAVLCVAAALCPEDRLVAALAATLLFSIAGERAASVSDCGPGSFIPHFVDELYSITNDCTARTFKVADNDNGVEEIVA
The following text describes a protein:
Function:
In addition to its role as an aminoacyl-tRNA synthetase, has also cysteine persulfide synthase activity. Produces reactive persulfide species such as cysteine persulfide (CysSSH) from substrate cysteine and mediate direct incorporation of CysSSH into proteins during translations, resulting in protein persulfides and polysulfides. CysSSHs behave as potent antioxidants and cellular protectants; Mitochondrial cysteine-specific aminoacyl-tRNA synthetase that catalyzes the ATP-dependent ligation of cysteine to tRNA(Cys).
Sequence:
MFLRVFRKYSTAKLTHDLRLYDGRLKEKVALQIHPSKSYLSFYTCGPTVYDSAHIGHASCYVRLDILQRILRHHFHLPLVTAMNITDIDDKIIARALEQQVDWQQLARRYEDEFWSDLQRLNVCAPDVKLRVTDHIPAIIRFVQTLVEKGFAYSTADGSVYFETAKYERYGKLQKVIIEPESNASKGQKRHQSDFALWKASKPGEPFWTAPGFSHGRPGWHIECSTLASHLFGRTIDFHAGGLDLRFPHHENEETQSCCYHDVPDWVTHWLHTGQLHLEGQTHKMSKSLKNTVSIGELLGAYSADEFRMLCLLSHYRSAIEYGPEAMGTARNVLRKFASFFSDAKAYIDGLKPAAYDATSTESLLGKLSNTRTTVREFLKNDFNTANSVLALGELASNVQRIINSHEPSTSGVSLIGSSNVGAVLAVTEYIREELVSYGVQSLDKQSPQHSRQMGNDANQSLEQLIEAMVATRSEIRLQAIETKNPQLFKVCDLLRDRLKLANVEVKDHGKTSSWNFREGSTK