lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Ribosome-dependent ATPase that functions in cytoplasmic translation elongation. Required for the ATP-dependent release of deacylated tRNA from the ribosomal E-site during protein biosynthesis (By similarity). Stimulates the eEF1A-dependent binding of aminoacyl-tRNA to the ribosomal A-site, which has reduced affinity for tRNA as long as the E-site is occupied (By similarity). Assists translation termination by stimulating the release of nascent protein from the ribosome by release factors (By similarity).
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MAPAPSAAGVPATVPAKAVKGAAGAAAKAGAAAEKKEASAETDALLSGDKDAAQELTNLVKIEGPAALANLGIEAVILKGLGDKKNATAREGACTLLANLCEQGVGHEVEPFIFENVLNSLVEAMGDKEKAVQKASLETLKAFVRVMSPWAAQQVLKVVLHQARTAGKWQVKTGCVALLEEMVTACPERMAALMPEIIPVMTEVIWDTKTDVQKASRAALTKLCALISNKDIERFIPALINSLIHPVEEVPKTIQLLSATTFVQEVDSATLALMVPLLSRGLNERPTATKRKVAVIIDNMTKLVDNERTVRPFLGKLLPGLIKIESTLADPEARSVVQRAIKTLREVGKVTGDGSDVKPLEDVDIKATQEQVNKALGEQSLQAQADLSSYLAVLVANLANARNFELTEWESTLIPYITLIKGSKPEQAKAVAKSLLTALAKSTGDTVEIFDDEEEGEDLCNCQFSLAYGAKILLNTATLRLKRGHKYGLCGRNGSGKSTLMRAITNGQVEGFPSPDEVRTWYVEHDLDGSEGLMTVLEFILADERLSMTRDEAVATLHEVGFDDARQNSPIAGLSGGWKMKVALARAILFKADILLLDEPTNHLDVVNVKWITDYLVNLKTATAIIVSHDSKFLNDVCTDILHLNRFKIKRYPGNLDAFVKRVPEARAYAELNTGEDYSFKLPDPPLLDGVKTKEKSLIKMKDVVFQYPGTPAPQLRGVSIQLSLASRVAILGPNGSGKSTLVKLIVGDTEPGSGEMWKHPNLVIGYVAQHAFHHIDQHLDKTPLDYMLWRYQTGEDLEEHMKANRALTAEEEAAKKQGEVFVIEGVKRLFDEIVGRKKLKNSFQYEVSFKNMSSADNQWVPRDDLINRGLERAVLAFDSKEAQRLGMNRPLVRKEIENHFEDFGLEREFTSHNTMRGLSGGQKVKVVLAAATWRRPHIIILDEPTNFLDRESLAALIKAIESFQGGVGIITHSKEFSEGTCKEIWAMNDGVLVASGHDWTESNSKGTKLEKKEEDDEYTDAMGNVHKKEKKAKKESASDRRKAKKDRMARKKAGTYDSADELEDL
The following text describes a protein:
Function:
Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.
Sequence:
MELQSELGAMLTTTGDDAQCSESSPEPCQLPQDTGGSEEGGDVPSASQRSPELQPAVEEEVPHPSTTEDPAEHQESRSRGAQEELPTPGESDASPGGAPQAAAEPPSARSPTREPEPDFYCVKWITWKGERTPIITQSENGPCPLLAIMNILFLQWKVKLPPQKEVVTSDELMAHLGDCILSIKPHEKSEGLQLNFQQNVNDTMMVLPKLSTGLDVNVRFTGVSDFEYTPECIVFDLLNVPLYHGWLVDPQSPEVVRAVGKLSYNQLVEKIITCKHSGDPNLVTEGPPVLAGDGPGLPAGGARGVGEPSQRGRRQLLLRHAVPPQPCPGQRGGRAGAEPAGPGLHDGPIPAAAAGPGPLSTQRPGAGTAAAAGGVPAAAAAAPPGPPAGPSTAGRPPDTGAETAAQTELGLHPPVADPPGTPPSCRDPLQVLGTMWCEMWGWGGPSLHSAGTLPVFPVALTWG
The following text describes a protein:
Function:
Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the first glucose residue from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide intermediate Man(9)GlcNAc(2)-PP-Dol to produce Glc(1)Man(9)GlcNAc(2)-PP-Dol. Glc(1)Man(9)GlcNAc(2)-PP-Dol is a substrate for ALG8, the following enzyme in the biosynthetic pathway.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MQTWSLISICVLLGVVVRWGVSLNSYSGAGKPPMFGDYEAQRHWQEVTYNLPIREWYFNSTNNDLAYWGLDYPPLTAYHSWLCAYIANIINPEWVKLHKSRGHESPEHKLFMRTTVLVVDLLLFIPAVVLYCLYLTDGSSKKKVSVLLCILLYPGIILIDYGHFQYNGVSLGLALWGILGLGLGWDALGSIAFSLALNYKQMELYHALPFFCYLLGKCFKAGLIGHGFFLLVRIAAAVVVTFALCWLPFLSDPAQALQVVRRIFPVARGLFEDKVANTWCSLNVLIKIRTLMSSDAQLYLSLVFTLLAVLPSSIRLLTRPTFWHFKLALVNSSLGFFLFSYQVHEKSILLAALPVCLLLDDLPFMSVWFLLASTFSMLPLLLKDGLLVPYAVTSTGFLLLSIYLLSALDHCTEDELQLTTYRKLFFFPFKSDLGCIVRWKFYISVAAMVGLSITSVTLDPPSHLPDLFPVLVSTTAYLLFLGTIIHFNILQFSGPPSKKSQKKSN
The following text describes a protein:
Function:
Controls stomatal patterning.
Subcellular Localization:
Secreted.
Sequence:
MVMNTTTSIGILSVSIVTLVLMLLVDSSQSLRPYHFTYHGKETNKDNQNHIHLKEEEKGDHELGMEMYPTGSSLPDCSHACGPCFPCKRVMVSFACSIAESCPIVYKCMCKGKYYHVPSN
The following text describes a protein:
Function:
Probable transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MGRGRIEIKRIENNTSRQVTFCKRRNGLLKKAYELSVLCDAEVALIVFSSRGRLYEYANNSVKATIERYKKAHTVGSSSGPPLLEHNAQQFYQQESAKLRNQIQMLQNTNRHLVGDSVGNLSLKELKQLESRLEKGISKIRARKSELLAAEISYMAKRETELQNDHMTLRTKIEEGEQQLQQVTVARSVAAAAAAATNLELNPFLEMDTKCFFTGGPFATLDMKCFLPGSLQQMLEAQQRQMLATELNLGYQLAPPGSDAADNNPHHQF
The following text describes a protein:
Function:
Activator of the gluconeogenic enzymes FBP1 and PCK1 genes.
Subcellular Localization:
Nucleus.
Sequence:
MANNNSDRQGLEPRVIRTLGSQALSGPSISNRTSSSEANPHFSKNVKEAMIKTASPTPLSTPIYRIAQACDRCRSKKTRCDGKRPQCSQCAAVGFECRISDKLLRKAYPKGYTESLEERVRELEAENKRLLALCDIKEQQISLVSQSRPQTSTDNTINGNFKHDLKDAPLNLSSTNIYLLNQTVNKQLQNGKMDGDNSGSAMSPLGAPPPPPHKDHLCDGVSCTNHLHVKPTSTSLNDPTAISFEQDEAPGLPAVKALKSMTTHQRSTQLATLVSLSIPRSTEEILFIPQLLTRIRQIFGFNSKQCLYTVSLLSSLKNRLPAPRLLAPSTSTKLKEKDEDKKLDDDSAFVKRFQSTNLSEFVDLKKFLISLKFNINSFSKQSEKPANDQDDELLSLTEIKELLHLFFKFWSNQVPILNNDHFLIYFNNFVEVVKHLSTENLETNNTTKSTVTTNHEIFALKLLMMLQMGLLVKIKMEKIKYTVPKNPKAKYARLMAYYHQLSLIIPKNPYFLNMSTTSLPSLQLLSLASFYYLNVGDISAIYGVRGRIVSMAQQLRLHRCPSAVLSVHSNPVLQKFEQSERRLLFWAIYYVDVFASLQLGVPRLLKDFDIECALPISDVEYKDQLSMENEKADKKAKKIQLQGQVSSFSLQIIRFAKILGNILDSIFKRGMMDERITSEVALVHENALDNWRNQLPEMYYFQITVNGTVNLDEIRATNQRNTETKFDKKDIILFEKKILLLFYFLAKSMIHLPVIATKPLPKNVDNATKKKQSMFNNDSKGATNQDHMILDVDMTSPAIRTSSSYIILQQATNATLTIFQAINSMYLPLPLNVSRTLIRFSLLCARGSLEYTKGGALFLDNKNLLLDTIKDIENDRLLDLPGIASWHTLKLFDMSINLLLKAPNVKVERLDKFLEKKLNYYNRLMGLPPATTTSLKPLFGSQSKNSLENRQRTPNVKRENPEHEYLYGNDSNNNNNSEAGHSPMTNTTNGNKRLKYEKDAKRNAKDGGISKGENAHNFQNDTKKNMSTSNLFPFSFSNTDLTALFTHPEGPNCTNTNNGNVDVCNRASTDATDANIENLSFLNMAPFLQTGNSNIGQNTIENKPMHMDAIFSLPSNLDLMKDNMDSKPEQLEPVIKQNPENSKNNQFHQKGKSTNMEKNNLSFNNKSNYSLTKLMRLLNNDNSFSNISINNFLYQNDQNSASADPGTNKKAVTNAGANFKPPSTGSNTSQGSILGSTKHGMDNCDFNDLGNFNNFMTNVNYSGVDYDYIVDASLGLAPLLVDTPDISNTNTTSTTSNRSKNSIILDTTFNDDLDRSRMNAREVLNPTDSILSQGMVSSVSTRNTSNQRSLSSGNDSKGDSSSQENSKSATGNQLDTPSTLFQMRRTSSGPSASHRGPRRPQKNRYNTDRSKSSGGGSSNTDNVSDLFQWQNAK
The following text describes a protein:
Function:
Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
Subcellular Localization:
Cytoplasm.
Sequence:
MMPSHDFRAPRLFVDAPLAQDARVPLDRDQSNYLGNVLRLAAGAEVLAFNGRDGEWQAAIEGRKRPDGLVILQQTRPQDRLADLTYVFAPLKHARLDYMVQKAIEMGAAGLQPVLTRFTQASRVNTERMRANVVEASEQCGILSIATVAEPVPLERFLSQRAAGRLLIFCDEAAEVENPVQSLQGAREAGQGIDVLIGPEGGFAEEERALLLRQPKILRLALGPRIMRADTAAVAALALVQTVLGDWGGKTP
The following text describes a protein:
Function:
May contribute to dephosphorylation of 'Tyr-15' of cdc2.
Subcellular Localization:
Cytoplasm.
Sequence:
MTKNIQVLFVCLGNICRSPMAEAVFRNEVEKAGLEARFDTIDSCGTGAWHVGNRPDPRTLEVLKKNGIHTKHLARKLSTSDFKNFDYIFAMDSSNLRNINRVKPQGSRAKVMLFGEYASPGVSKIVDDPYYGGSDGFGDCYIQLVDFSQNFLKSIA
The following text describes a protein:
Function:
Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MASLYPLKFNEKLAFFYNTVAATLWFCCLGRFLILLPLVGRKFLPGGMADFFHVVSLLPIIESLFVKSVLRKKFTITSLWGISNGLKMVWLCYGVIFPHPKIAKHTSYSLLITSWCLQYFIHYFYYAFKVKTKSSFHFLFWLEYNNFYLTYPLGLVSEMILLFLSLAFVEQDSIYDYVLRAAFLAYIPIAYFAWGHLKSRKKKRYTEIMNKRNVRQVATLESTTTSTKNTSIELRNM
The following text describes a protein:
Function:
Necessary for protein translocation in the endoplasmic reticulum.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MVEKSPSSTAVGAGRSPSKAVASRGSSGGQLRQRKAGGSTASRTTRPTAASSSGMWRFYTEDSPGLKVGPVPVLVMSLLFIASVFMLHIWGKYTRG
The following text describes a protein:
Function:
Acts as a component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.
Miscellaneous:
MISCELLANEOUS: Present with 1380 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus. Bud neck.
Sequence:
MRIFSGDNKVVDSLASNPGLMSPSNFGGDFGSRLKVNVTSKKKLNDSSPTSPMESSPVSPELVPILTLLNAHTHRRYHEGVFLILQDLNNNGTHAARKWKDVYGVLLGTQLALWDAKELAEFTDPSCPVSEKKLKEVASKPTYINLTDATLRTLDNSDNIVMECGKNLTNALVVSTTLKNRYFLQFGNKESFNAWNSAIRLCLYECSSLQEAYTGAFISSRGAKLGDIRILLTNRKYDYKDWVSVRFGAGMPWKRCYAVISQSSSKKKGHFGEINLYENDKKVKKNHAMATIVEAKALYAVYPSSPKLIDSSTIIKVVGSVKFEKKESAQEKDVFIMPEKHQAVPSYDTIIRFLIPAMDTFKLYGRPEKLLSSKNDPHSLLFGLPVLPHIYYLEVEDLLPLTNSVSSLHWSNNEWKEHISDILQRKIAQGYCGCNSTSNITSPLPSPFLGSADLFERADGVLSPKLSYGSKSSSNNSSKNSLPKRERVKLSSSSEQDLNNSDSPSIKRKSPPLVISESPHKVHTPTDASFRTRVTEGSPYAKQRHPKPFASSVNDSPSDRAKSRTVPYNNNDRKATTPEKFERGETSCGKNVDESLEKVRNMKLEIPESNFDKFMTDKNLLSVDSKCSNEKKLSVESDLSAIYEKYSNGPFGHTEGLNGSSDETYLRFQRASVHSESNYNSRKSFTPSDFSNGNEEEHAVLQELNSLTQRINELGMESINSNSDSDRINGSYSQVDFGNNNDEDDMNLFDPDFMAQDQLRAEERDYNKDDRTPLAKVPAAFQSTGLGITPDDDIERQYITEHRSRHEVPKRSPEKPSNPLEIGNPYAKPGTRLNTTHTHSKTDRSITPQRGQPVPSGQQISSYVQPANINSPNKMYGANNSAMGSPRNPKTRAPPGPYNQGWNNRPSPSNIYQRPHPSDTQPQAYHLPGNPYSTGNRPNMQAQYHPQQVPMPILQQPNRPYQPYAMNTHMGSPGGYAGAAPPFQPANVNYNTRPQQPWPTPNSPSAHYRPPPNLNQPQNGSAGYYRPPAPQLQNSQARPQKKDGFSQFMPSATTKNPYAQ
The following text describes a protein:
Function:
Involved in cuticle formation. May play a role in the unfolded protein response.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MFRLVGLFFLVLGASAAVIEEEENVIVLTKDNFDEVINGNEFILVEFYAPWCGHCKSLAPEYAKAATQLKEEGSDIKLGKLDATVHGEVSSKFEVRGYPTLKLFRNGKPQEYNGGRDHDSIIAWLKKKTGPVAKPLADADAVKELQESADVVVIGYFKDTTSDDAKTFLEVAAGIDDVPFGISTEDAVKSEIELKGEGIVLFKKFDDGRVAFDEKLTQDGLKTWIQANRLALVSEFTQETASVIFGGEIKSHNLLFVSKESSEFAKLEQEFKNAAKQFKGKVLFVYINTDVEENARIMEFFGLKKDELPAIRLISLEEDMTKFKPDFEEITTENISKFTQNYLDGSVKPHLMSEDIPEDWDKNPVKILVGKNFEQVARDNTKNVLVEFYAPWCGHCKQLAPTWDKLGEKFADDESIVIAKMDSTLNEVEDVKIQSFPTIKFFPAGSNKVVDYTGDRTIEGFTKFLETNGKEGAGASEEEKAEEEADEEGHTEL
The following text describes a protein:
Function:
Required for mitochondrial protein synthesis. May be involved in mitochondrial ribosome biogenesis.
Miscellaneous:
MISCELLANEOUS: Present with 189 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MSIAWSSVFKRELRLERFLPRVYSTKVPDNAPRAADNEQWLETLRPITHPEQKKSDHDVSYTRHINVPLGEVTSVNYLQRYNKHKHSQGNFVDVRIVKCKSGAGGSGAVSFFRDAGRSIGPPDGGDGGAGGSVYIQAVAGLGSLAKMKTTYTAEDGEAGAARQLDGMRGRDVLIQVPVGTVVKWCLPPQKVRELVEREMRKDNNATLRSILGSTAVNLSVSSGSHRKKIQLYRHEMAESWLFKDKAKEYHENKDWFKDLHKKMEAYDHSLEQSELFNDQFPLAGLDLNQPMTKPVCLLKGGQGGLGNMHFLTNLIRNPRFSKPGRNGLEQHFLFELKSIADLGLIGLPNAGKSTILNKISNAKPKIGHWQFTTLSPTIGTVSLGFGQDVFTVADIPGIIQGASLDKGMGLEFLRHIERSNGWVFVLDLSNKNPLNDLQLLIEEVGTLEKVKTKNILIVCNKVDIDAEKSESFAKYLQVEKFSKSQEWDCVPISALREENIDVLKKKMFKCARQSEFDK
The following text describes a protein:
Function:
Functions as a GTPase-activating protein (GAP) for ced-10/rac-1 and CDC42.
Sequence:
MEGIEESFAPLSPKSPFARRNGRSLRIQRLVDCQHFHYSSVELGPVRVAIIAINADENATERIKMRVESESNSWLVERSREDWAVFDRQLHRCVFERRHSRLDELFPLIHLETAKFEEVLVKYTERLSELTGSIITCYPVLKFLEIDSRGGHFEPAEETSINVPAIAAAVVTKDFEPTESSQLRLRVGDIVSITEMSTASPSEQTFWKAKLTISNQKIVDPQNARLGFEIGYFPRDCVMLIDDKRLPNPLNNEQKASTRNARRYMTTMFRNRRREPIFGLELTDLYMRTGKKVPVIVEKCCASIEDQGIVTGIYRQCGIQSNIQRLRAKFDSGAEPDLHEFGQRDIYSVSSLLKQYFRQLPNPLFTYQAYPKLIEAFEKEDSLSEKVESLRFSLETMPEAHYRTAKFLMEHLTRLCKSKSLTDMTSKNLAIVWSPNLFRPPPTLNGADTHLLSGLNVHTAICDFFIENSESLFVNDIDEEQSKCTSVENSFTTISKSATMSDMRSESESKWPRFFRGKSVEGFWKFNRKQQTSTGELCGSPTSEVKWRSRSTRSHSTDAAFQSSRTDSFIQLMHTGMDQIREGMRIFRARARSMRPTSRPPPSPRTRRARFSNGSSNNVQKLNESDIQHEIPLATTEPSITPEPKNTVDPHQIMTRTISVNDSDDQSFEENGLREMRERKVMFKAATQEHVATFHERSSPVEEWSSDSRESLHLEMSRYDNVSPSGTITRNQREPITNLSPAAQMLFFESSRASHLFSA
The following text describes a protein:
Function:
Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal transduction. May be involved in the uptake of lipoprotein APOE in liver.
Subcellular Localization:
Membrane, coated pit. Membrane; Single-pass type I membrane protein.
Sequence:
MLSALPFLLLLLLGGALARPDRIPFLNSACEAPPAVLLEVQGTLQRPLGRDSRSSPANCTWVILGSKEQTVTVRFQKLHLACGSEHLILHSPLQPPVSLCEAPAGPLQLPGGNVTITYSYAGARAPMGQGFLLTYSQDWLLCLQEEFQCLNHRCIPAAQRCDGIDACGDGSDEAGCRSDPFPNPVPAPTPPCNLTLEDFYGVFSSPGYSHLASVSHPQSCLWLLDPHDGRRLAVRFTALDLSYGDAVHVYDGAGPPETPRLLRSLTHFSNGKAVTVETLSGQAVVSYHTVAWSNGRGFNATYHVRGYCLPWDRPCGLGSGLGASENLGERCYSEAQRCDGSWDCADGTDEEGCPGCPPGHYPCGAAGTPGATACYLPADRCNYQTFCADGADERRCRHCQPGNFRCRDEKCVYETWVCDGQPDCTDGSDEWDCSYALPRKVITAAVIGSLVCGLLLVIALGCTCKLYAIRTQEYSIFAPLSRMEAEIVQQQAPPSYGQLIAQGAIPPVEDFPTENPNDNSVLGNLRSLLQILRQDMTPGGTSGGRRRQRGRSVRRLVRRLRRWGLLPRTNTPARAPETRSQATPSVPSEALDDSTGQACEGGAVGGQDGEQAPPLPIKSPIPTPSTLPALATASEPPGPLPSVPVESSLLSGVVQVLRGRLLPSLWPPGPTWTPTGTHTAVLPLEDEDDVLLMPLAEPEVWVVEAEDEPLLA
The following text describes a protein:
Function:
Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.
Sequence:
MSETTARRDADAVLRARAEIDLAALRANVRALRERAPGAALMAVVKADAYGHGAIPCARAAVAAGATWLGTATPQEALALRAAEPGLPDDVRIMCWLWTPGGPWREAVEARLDVSVSAMWAMEEVTGAARAAGVPARVQLKADTGLGRGGCQPGADWERLVGAALRAEEEGLLRVTGLWSHFACADEPGHPSIAAQLTRFREMTAYAEQRGLRPEVRHIANSPATLTLPDAHFDLVRPGIAMYGVSPSPEIGTPADFGLRPVMTLAASLALVKQVPGGHGVSYGHHYTTPGETTLGLVPLGYADGIPRHASSSGPVLVDGKWRTVAGRIAMDQFVVDLGGDRPEPGAEAVLFGPGDRGEPTAEDWAQAAGTIAYEIVTRIGSRVPRVYVNE
The following text describes a protein:
Function:
Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia (By similarity).
Subcellular Localization:
Cytoplasm. Dynein axonemal particle.
Sequence:
MTTPAGSGTGYGSVSWWGLSPALDLQAESPPVDPDSQSKTERKVPELDALLLGSVDGRHMLRTLARAALWPLRSFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLANLVLEPDRLEEQLPWLSLRLLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHIQEFRRWRDTGVAFELRDLSAYHVPNRTLASGRLLSHRGERVAARGYWGDIATGPFMAFGIEADDQSLLRTRNGQPVKTASEITQHNVTELFREVAAWRGPRAIQGNVEETESPEPDVPAQEPFTIHFLPLDSSQTLHHKTCYQGRFQLLYVSCGMVHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIARVAGFAPHTATKPSETFARFYKLGDSTPGGGDSAVESGPAPSKVESTRAPLPESISPPQANQAPSLEAMSPPLADLAPPLETMCPPQANQAPPLEALSPSKADQIPPLEAMSPPQAKLVLPVEAISLPQADLASPPEVISPLQEAMATSWVNAPPKHVT
The following text describes a protein:
Function:
Evades nuclear antiviral defenses triggered by dsDNA viruses. Acts during the initial stages of lytic infection and the reactivation of latent viral genome. Prevents the antiviral effect of nuclear bodies by degrading host PML and SP100.
Sequence:
MATVAERCPICLEDPSNYSMALPCLHAFCYVCITRWIRQNPTCPLCKVPVESVVHTIESDSEFKETKVSVDFDYDSEEDEDSFEGQFLAVDSGDAPANISAWNGPMAFVPLNANGTAGAPRLQPLVDWLVERLDQLFETPELALVMRNIVMDTLCEHGCNEEELTRQFWPMFHEDTVPFVTDLIVQAELCVASRPILPIARGRGVEYIDSSSSSSSSEEETDSDIEVDPNNLTDPEDTSDETSTDNSSAQAPRQEDSRPARARPGPPTRGRRRGRRPAAPGPASRRSARLRRRQPRTNSRTNGGDNGEIIDLTLDSDGDTEPADVSGSLNTTDQPVLIPDEEEAAPASPHTSSNSAIICLVSELTPESEEPPRDQPVAPSGSSAGERPMRPRCSLREFARRFMALAPRDSSTSEAAGPSRLGAGPRATEPFSVAVVLVDRSSEGAGLFGGRFAQHVRRRTEDESARRRGNVLLRPRRQSVPPVPYPDIASTSPLIRQGGQRVRDLQRAFQTQPAEPEEMRCPHNCQRYRRNQ
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre-initiation complex (PIC) with RNA polymerase II and the general transcription factors. The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II. The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins. The essential MED11/22 heterodimer specifically functions in promoting stable PIC formation.
Miscellaneous:
MISCELLANEOUS: Present with 396 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MQPPYIQERLKSLNDIETQLCSMLQEASQVTFIFGELKRGNESVKPQFENHVKQFYERLDKSTTQLRKEIQLLDENVGTRLLPINVNKKALGQDTEKMEEQLDLLSAILDPSKSK
The following text describes a protein:
Function:
Catalyzes the reversible hydration of CO(2) to H(2)CO(3). The main role may be to provide inorganic carbon for the bicarbonate-dependent carboxylation reactions catalyzed by pyruvate carboxylase, acetyl-CoA carboxylase and carbamoyl-phosphate synthetase. Involved in protection against oxidative damage. Encodes a substrate for the non-classical protein export pathway for proteins that lack a cleavable signal sequence.
Miscellaneous:
MISCELLANEOUS: Present with 2330 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus. Mitochondrion intermembrane space.
Sequence:
MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK
The following text describes a protein:
Function:
May be required for motile ciliogenesis and flagellar genesis.
Subcellular Localization:
Cytoplasm. Cell projection, cilium.
Sequence:
MSEELDEEVLDGLTEVEKLYTVFHGASQEDVAYAKLFWNSLSLQPPIESRLVSSDIRQRLKVAKTPNTTNAAANQAPWSKRNEEIQQDAYLRQKQEEKQRYMEMAKNRDQIIALLKKQRDERIKKEMIAYKHKPKKGKLEEKRLAPKTLSSDVDEDQKEVQKLQ
The following text describes a protein:
Function:
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
Sequence:
MPLNKPNPALSILDHASKNNYAVPAMCVYNVEGILATVRAANKKRSPAMIQLFPWALHYADGLLVHAAAEAAKSAEVPVTVSMDHAQTPEIIRRAADIGGFDSIMVDMSHYEKEENLRLTRELVAYCHERGIATEAEPGRIEGGEDGVADTAELEGLLTTPEESEEFVDTGIDWLAPAFGNVHGEYGPRGIQLEYERLKSINEKVGDRVRLVLHGADPFTEEIFRKCIECGVSKVNINKVLNNEYVKVQREKAGRVPLTQLLEEATDEMQKAVEKCMDMLGSTGRY
The following text describes a protein:
Function:
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.
Subcellular Localization:
Cytoplasm.
Sequence:
MSTATATTATAQYRAVQRNNANDVVTQHADLVRRIAHHLAARLPASVEVDDLIQAGMIGLIEASRSYDSDQGASFETYASIRIRGSMIDEIRRGDWVPRSVHRRARDAAAAVRKIEQNTGRAAAATEVAAAMEMPLPDYLRLMEDAARGQVLSLESRIEDHGELDTTAKGGPNPQQMMERGEFGRELGKAIGQLPEREQLVLSLYYEQELNLKEIGAVLGVSESRVCQIHGQAVVRLRGRLKVFELADAGVEIDD
The following text describes a protein:
Function:
Precursor of non-enzymatic components of the classical, lectin and GZMK complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system; Putative humoral mediator released following cleavage by complement proteases (C1S, MASP2 or GZMK, depending on the complement pathway). While it is strongly similar to anaphylatoxins, its role is unclear. Was reported to act as a mediator of local inflammatory process; however these effects were probably due to contamination with C3a and/C5a anaphylatoxins in biological assays.
Subcellular Localization:
Cell projection, axon. Cell projection, dendrite. Cell surface. Secreted. Synapse.
Sequence:
MRLLWGLIWASSFFTLSLQKPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSHNNVPCSPKVDFTLSSERDFTLLSLQVPLKDAKRCGLHQLLRGPEVQLVAQSPWLKDSLSRTTNIQGINLLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVTVENSHGLHVRKKEVYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKAEFQDALEKLNIGITDLQGLRLYVAAAIIESPGGEMEEAELTSWYFVSSPFSLDLSKTKRHLVPGAPFLLQALVREMSGSPASGVPVKVSATVSSPGSVPEVQDIQQNTDGSGQVSISIIMPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIERPDSRPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPSFYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAVGLAFSDGDQWTLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMRSCEQRAARVQQPDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDEDDIPVRSFFPENWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREFHLHLRLPVSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQVLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGAIHTEELVYELNPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGVASLLRLPRGCGEQTMIYLAPTLAASHYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFRKADGSYAAWLSRDSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQDPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAYALTLTKAPADLRGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPIPQAPALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVCPPMGRWTPGQNGGACALTPLCSPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYYPRVEYGFQVKVLREDSRAAFRLFVTKITQVLHFTKDVKATANQMRNFLVRASCRLRLEPGKEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQGCQV
The following text describes a protein:
Function:
Involved in transvection phenomena (= synapsis-dependent gene expression), where the synaptic pairing of chromosomes carrying genes with which zeste interacts influences the expression of these genes. Zeste binds to DNA and stimulates transcription from a nearby promoter.
Sequence:
MDPALHSIRGFSASTVCKKKRIKNVQKLELVRLMKANFLFIRGKHAIPRSEKSRADVWKVIAGRLNSLGPPVQSAEAWQRRWNDMRSATKSKMAKIQNYVREHGEDCPYELNLVERLIWETFSVKPDEYMRELNMKMWREKQQKCAGPTVGDSVSSCSSQLSVEQSFDMGWNQVETTVHDTGATGWSSSSFAFNDSEGGVMENTNRTSQPDQSFGPPAQTMEMNYAGYSGVSTSSNLIPSGSTDLVPGSNMLRELNKLFDLVLKQNEEILALLRQPAGNERW
The following text describes a protein:
Function:
Cleaves the beta-phosphate at the 5-position of soluble inositol pyrophosphates (By similarity). Has highest activity on 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate (5-InsP(7)) (By similarity). Acts as a negative regulator of defense responses against the fungal pathogen Magnaporthe oryzae.
Miscellaneous:
MISCELLANEOUS: Plants overexpressing DSP2 exhibit increased sensitivity to infection by the fungal pathogen Magnaporthe oryzae.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MQLEISPRQRSQQQKEEEGEHQQRAGEEAVGAVFSIEPWVDAAAVLVPPLNFAEVNDGIFRSGFPAADNFAFLLSLKLRSIVYLCPEPYPEENTRFLEQNGIKLHQFGIDGSKELLVNIPEEKIREALKVILDVRNQPVLIHCKRGKHRTGCVVGCLRKLQKWCLTSVFDEYQHFAAAKARSTDQRFMELFDTSSLMHLTASQC
The following text describes a protein:
Function:
May be a cell surface adhesion protein.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MGLNASLCLFSLTFLLVFFSTAITADNITQAFEKYSNFSTMNDLLIKTKLNIPISKYLTITLLAVSNEAITPIINRSDVELKNILMNHVILDYYDEMKFNGMKEKSIMLTTLYQTTGLGEEMNGFLNCTKSKGRVYFGSGVKGSPLVAEYVKALYHNPYNMSIVQISMPIVAPGLSLAIFPPPPPPAPPAPAPSPMNAAKAPGPGPADEDNASDTDVPKHTPTTETAEVDSPAPTPSADNEKVEAADKAGTSSSACKASLRFDVVLLLLLFGSFAGL
The following text describes a protein:
Function:
Actin-binding protein which may have an oncogenic function and regulates cell proliferation, migration and invasion in cancer cells.
Sequence:
MASGSAGKPTGEAASPAPASAVGGASSQPRKRLVSVCDHCKGKMQLVADLLLLSSEARPVLFEGPASSCAGAESFEQCRDTIIARTKGLSILTHDVQSQLNMGRFGEAGDSLVELGDLVVSLTECSAHAAYLAAVATPGAQPAQPGLVDRYRVTRCRHEVEQGCAVLRATPLADMTPQLLLEVSQGLSRNLKFLTDACALASDKSRDRFSREQFKLGVKCMSTSASALLACVREVKVAPSELARSRCALFSGPLVQAVSALVGFATEPQFLGRAAAVSAEGKAVQTAILGGAMSVVSACVLLTQCLRDLAQHPDGGAKMSDHRERLRNSACAVSEGCTLLSQALRERSSPRTLPPVNSNSVN