lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Sequence:
MMDLSALAEALPPLDQGDVTLVVCEGPDGFPEKLLGTEGENAQGSIREQASDGGFGESPKGAGGHATKFLAHKSVLLSSSDYFKSLFSNFKEATQETVTVHWDATIFAKVLGFLYGKELNIEPNDILPLIQSAYMFGIESLLGQCRNWISSCTPRPGQESGPVVDLESACGLWTAAKDVARDAAAADAVAELCVVTLAVFFEDAVAQQALREAPLELLMAVVNSEHLTVPSEKVVCEALLDWATDKCADVWSLAAKEIRWAMLPLPFRLGLRRRSPPLGSVLDAALLAASQPRASASSKRQPTLSKDFLPRVSEFLEGLDLRGCQQFNEASFFSLFRRPCPRLTRLDLSDCWRLRHHALLFGLADLLPSLAHLTAVNCPHLPSAFLLGEGHPNLQSLDLSVSSGQPKRRPYEPSPDWMLPGWAPDEAPTQFDDIWTPRPVRRAPANKILGPGGYSDPAVLSQRGLVQPRCAYPRLVDIALRKRSDVGAPLLHLLASTCPNLTSLDVSWCPDVADDSLAALLLKLPRLTELRAAGTKFGRESAAALLARDGWTQGTDEPSRGSIEAADAAASVREGTEQPASTFPSGKPCGENANSGPLLGARAEQGGFEAPTSGVLGADVSWLRVLDVSHCRELGGQHAAALTAGLDRLEEISLSGIVASGSFSFASSSIRRLDVNGLRIPGDELAMLLRKNPRLQRLDVRGCNQVGSRECSLDDGGDCSRLGMKDGCSRAESTSSGKTDGHRVGSKSAAERSADGHRQAEEPFSVGPSEQPAVWGEGSKLETLKVSWGFGHGSFRRLGSALGQLRSLTLGLGAAVSDADLAELAGACPRLEHLRLRMLMISGEGILPVVRQAQHLSTLSLHHCAGPFTPRLLDTLCGSAAGASLRTLKLIGGISTLDDACIARLANGLPTLEKLALAGARRLTPAALKLIAEGWPALRHLALENCGRVTADGADVLFTSCFALASLKLVHSGRGLPVDFIRAAHDRMPMLTSLFLDGCDAADGKFALIEPMATSVQGPLQSIQIGKCKKDKALHPAIRMSDPENYSTLVRICIDKIEL
The following text describes a protein:
Function:
Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
Miscellaneous:
MISCELLANEOUS: Was identified as a high-confidence drug target.
Sequence:
MRSVQEHQRVVAEMMRACRPITVPLTQAQGLVLGGDVVAPLSLPVFDNSAMDGYAVRAEDTSGATPQNPVMLPVAEDIPAGRADMLTLQPVTAHRIMTGAPVPTGATAIVPVEATDGGVDSVAIRQQATPGKHIRRSGEDVAAGTTVLHNGQIVTPAVLGLAAALGLAELPVLPRQRVLVISTGSELASPGTPLQPGQIYESNSIMLAAAVRDAGAAVVATATAGDDVAQFGAILDRYAVDADLIITSGGVSAGAYEVVKDAFGSADYRGGDHGVEFVKVAMQPGMPQGVGRVAGTPIVTLPGNPVSALVSFEVFIRPPLRMAMGLPDPYRPHRSAVLTASLTSPRGKRQFRRAILDHQAGTVISYGPPASHHLRWLASANGLLDIPEDVVEVAAGTQLQVWDLT
The following text describes a protein:
Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MNLFSSSILLSLTLLITPFIITTTKKYETHAYPYYVKNSIACAFMTSLVPMLMFLYTNQEMIISNWHWMTIHTMKLCLS
The following text describes a protein:
Function:
Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells.
Subcellular Localization:
Secreted.
Sequence:
MKVSAARLAVILVATALCAPASASPHASDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNPAVVFVTRKNRQVCANPEKKWVREYINSLEMS
The following text describes a protein:
Function:
Hydrolase that deubiquitinates target proteins (By similarity). Cleaves the UBL propeptide in sde2.
Subcellular Localization:
Nucleus.
Sequence:
MVTGETLVDSQKSLINNDTLLNEKLKEDFEENVSIDVKIHEELRRALPDYEESGFQRFTWHIKSWHELDRRAVSPQFAVGSRQFKITYFPQGTLQSAGFTSIFLEYIPSEEEKLSNKYGCCCQFAFVISNPRKPSLSVANSAHCRFSPEIVDWGFTQFAELKKLLCRQAPDVPPIVEDGALLLTAYVRILKDPTGVLWHSFNDYDSKIATGYVGLKNQGATCYMNSLLQSLYIIHAFRRIVYQIPTDSPQGKDSIAYALQRCFYNLQFMNEPVSTTELTKSFGWDSLDSFMQHDVQEFNRVLQDNLERSMRDTKVENALTNLFVGKMKSYIACVNVNFESARSEDYWDIQLNVKGMKNLEDSFRSYIQVETLEGDNCYFADTYGFQEAKKGVIFESFPPILHLQLKRFEYDFERDMMIKINDRYEFPLEFDAKAFLSPEADQSQNCEYVLYGVLVHSGDLHNGHYYALLKTEKDGPWYKYDDTRVTRATLREVLEENYGGDYIMHPPFRSPVKLKRFMSAYMLLYLRKDKLDELMNPVSADEIPEHLKEALNPSIQLAELRRKERLESHLYTKVQLITPEFYSEHHEFDIADFGNAYKEETIPQFRIKKEAKFSEFIPIVAEKLGYPQECMRFWYVVKRHNCTVRVESPVNELNSTMEEVKNVWNSQGEILRLYLEITPENELSSSLTHQNTGEWNAFIFVKYFDRKSQEISGCGTLHVNKSDEIRSICPLLCERANLPKNTPLNIYEEIKPGMVDFLRLEKTFTQSELSTGDIICFEPCRPSALEDDIVNSGFDSALKLYDFLSNKVLVLFRPRFIDQDSIIEFEMLLDRRIKYDDLCIELGQKLGIGADHIRLTTCNPLTYSAGMVVPNDSNITLYEILYSSEEEMPSNVIFYETMDVSLSDLDRKRLVRLRWLVDGLANIELVEAYINKSGDINDLFGAVCERFPDSDLRKKKVRVYEVFESRYHRDLSLRTLIRTINPAATLVGEVVPLDQLQLYPEEKIVQVHHFHKDIARIHGIPFSFVIKPQEKFIDTKLRLAARTQYPESIFSVIKFCVVDFDNNRVVYLNDEDITYDVVEKLNGTLALDRAKKDSKKPNILDRAIQMKN
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MSKDGSPAAAAQPDQPAVADAAAVPSPPPTTTAEVKPLTIFYNGSVATFHLTQDKAEDIMNMAAGEEEEDGGGGGRRQLTAAAAISASSSGDQLLEKLKRELPIANKRSLVRFFQKRKER
The following text describes a protein:
Function:
Initiates the repair of damaged proteins by catalyzing methyl esterification of L-isoaspartyl and D-aspartyl residues produced by spontaneous isomerization and racemization of L-aspartyl and L-asparaginyl residues in aging peptides and proteins.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MAWHCSSTTNAGMVTALQREGLIKTPEVMEVMRRVDRGWFVRNSKDAYRDQPLPIGFGVTISAPHMHAIMLELVSPSVLRHKNLDRGHCQPLRLLDIGSGSGFMTAAFAALCEAAWRDGEPPMFEVVGIEHVQELQKQSKRVLESHFPEWIRERRVTLLHGDGRKPRSIAGVGEEKGECFDVIHVGATAPKTLVPEYLSLLRCGGTLVIPVGNPAEVQELQVFTKGDEGAFTMRRACHVQFVPLTSLHAQLDGDATTRT
The following text describes a protein:
Function:
Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.
Sequence:
MERTELLKPRTLADLIRILHELFAGDEVNVEEVQAVLEAYESNPAEWALYAKFDQYRYTRNLVDQGNGKFNLMILCWGEGHGSSIHDHTDSHCFLKLLQGNLKETLFDWPDKKSNEMIKKSERTLRENQCAYINDSIGLHRVENVSHTEPAVSLHLYSPPFDTCHAFDQRTGHKNKVTMTFHSKFGIRTPFTTSGSLENN
The following text describes a protein:
Function:
Plays a role in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage. Maintains together with TBC1D14 the cycling pool of ATG9 required for initiation of autophagy. Involved in collagen secretion.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
Subcellular Localization:
Golgi apparatus, cis-Golgi network.
Sequence:
MAQCVQSVQELIPDSFVPCVAALCSDEAERLTRLNHLSFAELLKPFSRLTSEVHMRDPNNQLHVIKNLKIAVSNIVTQPPQPGAIRKLLNDVVSGSQPAEGLVANVITAGDYDLNISATTPWFESYRETFLQSMPALDHEFLNHYLACMLVASSSEAEPVEQFSKLSQEQHRIQHNSDYSYPKWFIPNTLKYYVLLHDVSAGDEQRAESIYEEMKQKYGTQGCYLLKINSRTSNRASDEQIPDPWSQYLQKNSIQNQESYEDGPCTITSNKNSDNNLLSLDGLDNEVKDGLPNNFRAHPLQLEQSSDPSNSIDGPDHLRSASSLHETKKGNTGIIHGACLTLTDHDRIRQFIQEFTFRGLLPHIEKTIRQLNDQLISRKGLSRSLFSATKKWFSGSKVPEKSINDLKNTSGLLYPPEAPELQIRKMADLCFLVQHYDLAYSCYHTAKKDFLNDQAMLYAAGALEMAAVSAFLQPGAPRPYPAHYMDTAIQTYRDICKNMVLAERCVLLSAELLKSQSKYSEAAALLIRLTSEDSDLRSALLLEQAAHCFINMKSPMVRKYAFHMILAGHRFSKAGQKKHALRCYCQAMQVYKGKGWSLAEDHINFTIGRQSYTLRQLDNAVSAFRHILINESKQSAAQQGAFLREYLYVYKNVSQLSPDGPLPQLPLPYINSSATRVFFGHDRRPADGEKQAATHVSLDQEYDSESSQQWRELEEQVVSVVNKGVIPSNFHPTQYCLNSYSDNSRFPLAVVEEPITVEVAFRNPLKVLLLLTDLSLLWKFHPKDFSGKDNEEVKQLVTSEPEMIGAEVISEFLINGEESKVARLKLFPHHIGELHILGVVYNLGTIQGSMTVDGIGALPGCHTGKYSLSMSVRGKQDLEIQGPRLNNTKEEKTSVKYGPDRRLDPIITEEMPLLEVFFIHFPTGLLCGEIRKAYVEFVNVSKCPLTGLKVVSKRPEFFTFGGNTAVLTPLSPSASENCSAYKTVVTDATSVCTALISSASSVDFGIGTGSQPEVIPVPLPDTVLLPGASVQLPMWLRGPDEEGVHEINFLFYYESVKKQPKIRHRILRHTAIICTSRSLNVRATVCRSNSLENEEGRGGNMLVFVDVENTNTSEAGVKEFHIVQVSSSSKHWKLQKSVNLSENKDTKLASREKGKFCFKAIRCEKEEAATQSSEKYTFADIIFGNEQIISSASPCADFFYRSLSSELKKPQAHLPVHTEKQSTEDAVRLIQKCSEVDLNIVILWKAYVVEDSKQLILEGQHHVILRTIGKEAFSYPQKQEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQLKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV
The following text describes a protein:
Function:
Involved in the Hedgehog (Hh) signaling pathway, is essential for normal ciliogenesis. Regulates the proteolytic processing of GLI3 and cooperates with the transcription factor EMX1 in the induction of downstream Hh pathway gene expression and gonadotropin-releasing hormone production. WDR11 complex facilitates the tethering of Adaptor protein-1 complex (AP-1)-derived vesicles. WDR11 complex acts together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasmic vesicle. Golgi apparatus, trans-Golgi network. Nucleus.
Sequence:
MLPYTVNFKVSARTLTGALNAHNKAAVDWGWQGLIAYGCHSLVVVIDSITAQTLQVLEKHKADVVKVKWARENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQWLWNQDASRDLLLAIHPPNYIVLWNADTGTKLWKKSYADNILSFSFDPFDPSHLTLLTSEGIVFISDFSPSKPPSGPGKKVYISSPHSSPAHNKLATATGAKKALNKVKILITQEKPSAEFITLNDCLQLAYLPSKRNHMLLLYPREILILDLEVNQTVGVIAIERTGVPFLQVIPCFQRDGLFCLHENGCITLRVRRSYNNIFTTSNEEPDPDPVQELTYDLRSQCDAIRVTKTVRPFSMVCCPVNENAAALVVSDGRVMIWELKSAVCNRNSRNSSSGVSPLYSPVSFCGIPVGVLQNKLPDLSLDNMIGQSAIAGEEHPRGSILREVHLKFLLTGLLSGLPAPQFAIRMCPPLTTKNIKMYQPLLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSFLSFATSTPNNMGLVRNELQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRDKPLELWDVRTCTLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMARQTVVSDTELSIVESSVISLLQEAESKSELSQNISAREHFVFTDIDGQVYHLTVEGNSVKDSARIPPDGSMGSITCIAWKGDTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAMYNDGAEVWDTKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEMSMKSACFRMDEQELTEPVWCPYLLVPRASLALKAFLLHQPWNGQYSLDISHVDYPENEEIKNLLQEQLNSLSNDIKKLLLDPEFTLLQRCLLVSRLYGDESELHFWTVAAHYLHSLFQEKSASTTAPKEAAPRDKLSNPLDICYDVLCENAYFQKFQLERVNLQEVKRSTYDHTRKCTDQLLLLGQTDRAMQLLLETSADNQHYYCDSLKACLVTTVTSSGPSQSTIKLVATNMIANGKLAEGVQLLCLIDKAADACRYLQTYGEWNRAAWLAKVRLNPEECADVLRRWVDHLCSPQVNQKSKALLVLLSLGCFFSVAETLHSMRYFDRAALFVEACLKYGAFEVTEDTEKLITAIYADYARSLKNLGFKQGAVLFASKAGAAGKDLLNELESPKEEPIEE
The following text describes a protein:
Function:
Probable RNA helicase, which may be involved in modulation of the translation termination process. Probably unwinds double-stranded RNA. In vitro, unwinds covalently closed, circular DNA in the presence of a DNA topoisomerase TOP1 and replication factor-A protein RFA1.
Miscellaneous:
MISCELLANEOUS: Present with 736 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Note=Associated with polyribosomes.
Sequence:
MDFQCRTCSQAYDAEQMMKHLSSTRHKTVFDTSNDEDICCEECQDKNIHQLQIIRFGGEDMVLLCNSCFRKEYSETERPSTSYSLQNGSILKFWEKYVKVRECCCDECGEESNLNANRNGEVLCDKCLPKSNRAKDFVSEKSGRFLYIYLGLNETQNSTRKPRKKGGRRVGRGKKGRKGAKIKKEKKETFEAKISRIAYEVKKENSTIQSSSSSNLRNFKGFKAVESDPVVAAKVSKSETSRSNPGPSNRNKGKGNKANHKKNSGNGIGKEKERKTNIRNNVRNSQPIPEDRKNTNSHVTTNSGGKGKNESVDKHQLPQPKALNGNGSGSTNTTGLKKGKKDHAGQKTKGNDKTGNKNPREAKLNSAGRKNALGKKSNNQPNKGTSRWTIGSDTESSREPSISPNENTTSITKSRNRNKKASKPTLNEKSKTTTMPKKLETKNQEKNNGKTKDGKLIYEEGEPLTRYNTFKSTLSYPDLNTYLNDYSFALFLEQKLENEFVQNFNILWPRNEKDTAFIINVEKNNNSELEKLLPANLLALGRPAFNERQPFFFCTQDEQKVWYIFIKELSIQRGKYVLLVELFSWNNLSLPTKNGSSQFKLLPTSAQTSRILFAMTRITNPKFIDLLLGQKPIKEIYFDNRLKFSSDKLNRSQKTAVEHVLNNSITILQGPPGTGKTSTIEEIIIQVIERFHAFPILCVAASNIAIDNIAEKIMENRPQIKILRILSKKKEQQYSDDHPLGEICLHNIVYKNLSPDMQVVANKTRRGEMISKSEDTKFYKEKNRVTNKVVSQSQIIFTTNIAAGGRELKVIKECPVVIMDEATQSSEASTLVPLSLPGIRNFVFVGDEKQLSSFSNIPQLETSLFERVLSNGTYKNPLMLDTQYRMHPKISEFPIKKIYNGELKDGVTDEQKAWPGVQHPLFFYQCDLGPESRVRSTQRDIVGFTYENKHECVEIVKIIQILMLDKKVPLEEIGVITPYSAQRDLLSDILTKNVVINPKQISMQQEYDEIELFNAAGSQGTAGSLQNNVINIINGLHVATVDSFQGHEKSFIIFSCVRNNTENKIGFLRDKRRLNVALTRAKHGLIVVGNKNVLRKGDPLWKDYITYLEEQEVIFTDLTAY
The following text describes a protein:
Function:
Involved in inflammation.
Subcellular Localization:
Cytoplasm.
Sequence:
MSDVNPPSDTPIPFSSSSTHSSHIPPWTFSCYPGSPCENGVMLYMRNVSHEELQRFKQLLLTELSTGTMPITWDQVETASWAEVVHLLIERFPGRRAWDVTSNIFAIMNCDKMCVVVRREINAILPTLEPEDLNVGETQVNLEEGESGKIRRYKSNVMEKFFPIWDITTWPGNQRDFFYQGVHRHEEYLPCLLLPKRPQGRQPKTVAIQGAPGIGKTILAKKVMFEWARNKFYAHKRWCAFYFHCQEVNQTTDQSFSELIEQKWPGSQDLVSKIMSKPDQLLLLLDGFEELTSTLIDRLEDLSEDWRQKLPGSVLLSSLLSKTMLPEATLLIMIRFTSWQTCKPLLKCPSLVTLPGFNTMEKIKYFQMYFGHTEEGDQVLSFAMENTILFSMCRVPVVCWMVCSGLKQQMERGNNLTQSCPNATSVFVRYISSLFPTRAENFSRKIHQAQLEGLCHLAADSMWHRKWVLGKEDLEEAKLDQTGVTAFLGMSILRRIAGEEDHYVFTLVTFQEFFAALFYVLCFPQRLKNFHVLSHVNIQRLIASPRGSKSYLSHMGLFLFGFLNEACASAVEQSFQCKVSFGNKRKLLKVIPLLHKCDPPSPGSGVPQLFYCLHEIREEAFVSQALNDYHKVVLRIGNNKEVQVSAFCLKRCQYLHEVELTVTLNFMNVWKLSSSSHPGSEAPESNGLHRWWQDLCSVFATNDKLEVLTMTNSVLGPPFLKALAAALRHPQCKLQKLLLRRVNSTMLNQDLIGVLTGNQHLRYLEIQHVEVESKAVKLLCRVLRSPRCRLQCLRLEDCLATPRIWTDLGNNLQGNGHLKTLILRKNSLENCGAYYLSVAQLERLSIENCNLTQLTCESLASCLRQSKMLTHLSLAENALKDEGAKHIWNALPHLRCPLQRLVLRKCDLTFNCCQDMISALCKNKTLKSLDLSFNSLKDDGVILLCEALKNPDCTLQILELENCLFTSICCQAMASMLRKNQHLRHLDLSKNAIGVYGILTLCEAFSSQKKREEVIFCIPAWTRITSFSPTPHPPDFTGKSDCLSQINP
The following text describes a protein:
Function:
Catalyzes the conversion of deacetylcephalosporin C to cephalosporin C.
Sequence:
MLPSAQVARLKPDPFPPSLSPIPHGAVTFAALAPCHNLPIFSSRQMLRDSLTYSHTSPTMSPQIANRFEASLDAQDIARISLFTLESGVILRDVPVAYKSWGRMNVSRDNCVIVCHTLTSSAHVTSWWPTLFGQGRAFDTSRYFIICLNYLGSPFGSAGPCSPDPDAEGQRPYGAKFPRTTIRDDVRIHRQVLDRLGVRQIAAVVGASMGGMHTLEWAFFGPEYVRKIVPIATSCRQSGWCAAWFETQRQCIYDDPKYLDGEYDVDDQPVRGLETARKIANLTYKSKPAMDERFHMAPGVQAGRNISSQDAKKEINGTDSGNSHRAGQPIEAVSSYLRYQAQKFAASFDANCYIAMTLKFDTHDISRGRAGSIPEALAMITQPALIICARSDGLYSFDEHVEMGRSIPNSRLCVVDTNEGHDFFVMEADKVNDAVRGFLDQSLM
The following text describes a protein:
Function:
ATP-dependent chaperone that functions as an unfoldase. As part of the ClpXP protease complex, it recognizes specific protein substrates, unfolds them using energy derived from ATP hydrolysis, and then translocates them to the proteolytic subunit (CLPP) of the ClpXP complex for degradation. Thanks to its chaperone activity, it also functions in the incorporation of the pyridoxal phosphate cofactor into 5-aminolevulinate synthase, thereby activating 5-aminolevulinate (ALA) synthesis, the first step in heme biosynthesis. This chaperone is also involved in the control of mtDNA nucleoid distribution, by regulating mitochondrial transcription factor A (TFAM) activity.
Subcellular Localization:
Mitochondrion matrix, mitochondrion nucleoid.
Sequence:
MSHPGCFCTARIIASSLNRGFVCGRGHLALLKRPRSSEFHLVRKVPFRRFTVTTVYCASKDASKDGSGDGNKKSVGEGASKKSSGGSGKGGNQLRCPKCGDLCTHVETFVSSTRFVKCEKCHHFFVVLSEADSKKSIGKEPESAAEAMKLAFQQKPPPPPKKIFNYLDKYVVGQAFAKKVLSVAVYNHYKRIYNNIPANLRQQAEVEKQASLTPRESEIRRREDEYRFTKLLQIAGISPHGNALGASMQQQVNQQMPQERRGGDVLDSNHDEIKLEKSNILLLGPTGSGKTLLAQTLAKCLDVPFAICDCTTLTQAGYVGEDIESVIAKLLQDANYNVEKAQQGIVFLDEVDKIGSVPGIHQLRDVGGEGVQQGLLKLLEGTIVNVPEKNSRKLRGETVQVDTTNILFVSSGAFNGLDRIISRRKNEKYLGFGIASNMGKGRRAAAAADLANNSPESNAVQDIEEKDRLLRLVEARDLIEFGMIPEFVGRLPVVVPLHSLDEQTLVRILTEPRNAVVPQYQALFSMDKCELSISEDALRAIARLALERKTGARGLRSIMEKLLLEPMFEVPNSDIVCVEVDQEVVEGKKDPRYVKTQRKEVSEEEYDSGVEEEGWSRQADAANN
The following text describes a protein:
Function:
Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle.
Subcellular Localization:
Nucleus.
Sequence:
MERAENARIIQKPMTRRTVDYGSGVSKYVTDRLVRCNPYHIVRPRPNANQIINLYPPYEYPFDSAATFCTKYIHTSANKARHVINVVRWTPDGRRLLTGSSTGEFTLWNGLTFNFELINQSHDYAVRCAEWSNDGRWLLSGDGGGMVKYFEPNLNNVKIVQAHEMEVRDLAFSPNDSKFVTASDDGSLKVWNFHTSAEEQKLTGHGWDVKTVDWHPSKGLLVSGSKDNLVKFWDPRTGTCLATLHGHKNTIMQASFQRDTRNNLIATVSRDSTCRIFDLRTMKSIRVLRGHDKDINCLAWHPTNPNIVTTGGSDGSVNHYSLDEPPLLSQKWYHDRHPQVTLSASTTLLYPSASIPHAHELGLWSMQYHPLGHILCTGSNDKTTRFWSRSRPEDEESYLDRHHLGEEQSEVVLGKRKQPSNNEEEDQESMDGRSRAVSPAVSAMGAQPAGLPQLPGLGQMGTQQGPTESNVYDYSNGHSSSQAQYLPGLGFHNRHRGER
The following text describes a protein:
Function:
Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons (By similarity).
Sequence:
MADSHDAPFRLRSYQAEMVEESMQSNIICVMDTGSGKTHIAIDRTRAELEICRPDKIVWFLAPTVTLCEQQFAVFKSNLPGYGIQLLSGKDNLDHWTDQGVWDDVLLNIRIVLSTHQVLLDALSHGFVKMRNLSLLIFDEAHHCSLKHPAHRIMSDFYKPRIGTELPRILGLSASPIKTAKVTSEDLQQIERNLCATVKTPKLHRSELLRYVHRPHLMRIDYPVEPQDLQSNMLSFLKSAYTNYDLQKDPWVSELLQQRQQGHDVTKNIHKVFIGGKTYCRDQLRSLALKAEAMSQELGMSVMDWYLRGCITQFSKMVHMSDSQLLDWSADEKRHLLEILRTLPSIDLNSHDIPPMSLGSMSHKLQLLIKFLVAEAKHDPEFTCLVFVEQRVWVACIAEVLAIHPETRDLLRVGTFVGESENSKRKANIASISEPRNQQATLENFRAGKLNLILATSVLEEGIDVSSCHLVVCFESPKNLKSFVQRRGRARKEESKYVIFVPQAGRRRDPESWQSLEEGMKAAYLDDLRQVKLATEKEQQSETGHRNFEVKSTGALLTLDNASQHLHHFCSILGAGPYIDNRPQFEFTEIRPGVITARVILPLTVDPEVRTACALDTWATEKMAKQDAAFEAYKALYVAGLVNDNLLPARQEADDELSELQIPDHRPSLVPVSPTLDPWPLFARHQQQNPHVYYRTRLTLHTVDDKPKHLILLTPKILPDIPELLLYWNSSTKLKIESSWLHDVVLNDEEISELKSVTYKILYSVFHNRMELNRRDFVWLVAPCDESGLLDSRIWLSEWRQHTCLATELIAQNSDWSLWGLVNQKGDARKYTPRSTSMNNQLWLLQLMQLPKRRDFLHPVLESANINDAYTKTDEMAAKDCIVDPVPAPYSVFALLLPSILHRFGMAIIAETLRTTLLGPVALDSAHSLLLTRALKSSAADGNDNYQRLEFLGDCILKFIATVHLMAANPKWPESHLTAKKGRIVSNGFLARATIAAGLDRFMITKSFTGAKWAPRYAGDLLAETGPAVKEERSSKLIADIIESLIGACYTVGGFEKAVLCVQTLLPLEPWISVPAANSILHEAAPAEADLMGLDVLETLIGYTFKKKPLLLEALTHASFSGPHVHCSYERLEFLGDAVLDYIISKRLHAHSPELSHQKMHAIRTATVNASFLAFRLFETTIDEETINKTSMRPESQKRAIWQFLRSGSPSLNANRDNALRQHEQVRDEIIIGLNEAARFPWHLFALTDPPKFLSDMVESVIGAVYIDSLGDILTCEAIVRRLGILDCLDHILCNGVDCLHPKERLGHLAVDKGVQYARVGMNTEPNEGDKMYKCQVKVGGEDVGDVAEGLKRLNAETVAAWKAVGVLESRKDSAIEIVSDVEEFFDADDGGGISLDDP
The following text describes a protein:
Function:
Involved in the synthesis of glucuronoxylan hemicellulose in secondary cell walls.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MKFFAAPAGRAGLGAVVLVAASRCPLFFFALLVLLLFQPHHQLAASHVAVNQQVSLVPDAAAAKAAGVGNGAVVDVGDEEEEGSGSRWMLIVVTTTRSGGRERRRRNAALAHVEKHYFPGVVHFADAAGVYDAHFFDKIRQTESVLHPSIPFGFSLPFFLLDY
The following text describes a protein:
Function:
Essential determinant for low-affinity spermidine transport.
Sequence:
MTVSHNHSTKISQQPISSVSAFKFFGKKLLSSSHGNKLKKKASLPPDFHSTSTNDSESSSPKLPNSLKTSRRANSFAHTTNSKRSLSSASTKILPPAGSSTSISRGNRHSSTSRNLSNSKFSSERLVYNPYGVSTPSTSLSSVSTSMKKDPDLGFYLHDGDSKIRMLPIPIVDPNEYLPDEMKEASIQLSDNFVFDDENKTIGWGGSCEVRKIRSKYRKKDVFALKKLNMIYNETPEKFYKRCSKEFIIAKQLSHHVHITNTFLLVKVPTTVYTTRGWGFVMELGLRDLFAMIQKSGWRSVALAEKFCIFKQVACGVKFCHDQGIAHRDLKPENVLLSPDGVCKLTDFGISDWYHTDPHDLSSPVKKCAGMIGSPPYAPPEVMFYDSKKHYDTELQQPYDPRALDCYGLGIILMTLVNNVIPFLESCSFDTGFRDYCDAYENFIRLHDRAFRNRGNYRPGPGMEYHLARNFKNGHASRVAWRLADPEAATRYTIDDLFEDPWFQGIETCVDANDKYVCKKPIIKTTTYENPRGFHIATDVAATTPTSNPFLKNRVPIRSMVDIAAHPSPTATVLASSPPPPPPATHVPAEALFTLRETPPPQLATLTLSEEPPATPAPSAPSAPSARVRGHSPHRVVHHHLNIVNSLVHSSSAASSQVPAST
The following text describes a protein:
Function:
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Interaction with DPA induces an exclusive nuclear localization, but an interaction with DPB has no effect.
Domain:
The C-terminal region (366-485) is required for transactivational activity. The N-terminal region (92-128) is important for nuclear localization.
Sequence:
MSGVVRSSPGSSQPPPPPPHHPPSSPVPVTSTPVIPPIRRHLAFASTKPPFHPSDDYHRFNPSSLSNNNDRSFVHGCGVVDREEDAVVVRSPSRKRKATMDMVVAPSNNGFTSSGFTNIPSSPCQTPRKGGRVNIKSKAKGNKSTPQTPISTNAGSPITLTPSGSCRYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETLEVQKRRIYDITNVLEGIDLIEKPFKNRILWKGVDACPGDEDADVSVLQLQAEIENLALEEQALDNQIRQTEERLRDLSENEKNQKWLFVTEEDIKSLPGFQNQTLIAVKAPHGTTLEVPDPDEAADHPQRRYRIILRSTMGPIDVYLVSEFEGKFEDTNGSGAAPPACLPIASSSGSTGHHDIEALTVDNPETAIVSHDHPHPQPGDTSDLNYLQEQVGGMLKITPSDVENDESDYWLLSNAEISMTDIWKTDSGIDWDYGIADVSTPPPGMGEIAPTAVDSTPR
The following text describes a protein:
Function:
Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
Subcellular Localization:
Nucleus.
Sequence:
MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQTPFPLVPCLPIPLGCQAPIFGPLPGYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEFKTDWACRVPRNFFFPLSWVGGKGVTPLPLVWLLSGQLPTPGEALETTSGS
The following text describes a protein:
Function:
Required for salt tolerance and sodium (Na) homeostasis after salt stress. Together with BHLH148/RITF1, regulates the transcription of several genes involved in the detoxification of reactive oxygen species (ROS) generated by salt (NaCl) stress. Binds calcium.
Subcellular Localization:
Nucleus.
Sequence:
MHRDMYSSRGTGYGQQQYGSQSGYSQNLGSGYPGSSVSGGAEGGSQISLSSRHPSITGAPQETDIGGGYRSHLSTAASHYGTQYGSVYGSTSLSSSQPLSTNGLGSSVLDNRSGYVPTLPDSPKFASGSYLSPSSHGYGQKTDDLYSDKLSGYIPVDRRQYGEQSSSYLGRELQNEPTRRYADPSNFARQTDLYDRIDQASLLRGEQLLKMQSLHTSSVDAGVNRQTDYLTERSSTVRHSDQEAMHYGGRLESDPHGLSVRNTSSYASQHTPSLLGAVPRRNLDDYIYPESSSNPGYGVSLPPGRDYGTGKGIHSAASLDLDYPGGMLARGTGAAPRVDDLRKGDRASYLREFDLREEERRREDQRARDKEREREREREHDRERERQRERERQRARDRERERILERREKERQGERERERKRALEIKRDRTPTARATSKDTKERTPVPKSISRDARSSSLRRDAHHREASIRRSSPIKPIRRDYVCKVLSSRLVDMERDYVTLDKRYPRLFVPSEFSKVVVNWPKQKLTLSMHTAVSFEHDYIEDGGADVKSTSTKPLALKTGGKSVWNAKMVLMSGLSRTALEDLASDKFFEDRIPHICNILKFAVLKKDHSFMAIGGSWDPTDGMDPSVDQSSLIQTMLRHSKDKLHLDLSNCRHWNPFLEIHYDRVGTDGVFSYKEITVLFVPDLSECLPSFDVWRTQWLAHRKALTERDRLLSQEVKKDTVEVTKDAEKKSPGDTSGTPTTGTKKTVKKIIKRVVKRPVNDGKATGMKGEKSDVPEHVAIPETTVPKEESTGTSSNKKIVKKVAETGDTSDPSAKANEQTPAKTIVKKKIIKRVAKRKVAEIDNKMDGDSKKDGDSDEKKVMEVGKKSSDSGSVEMKPTAESLEDVKDENASKTVDVKQETGSPDTKKKEGASSSSKKDTKTGEDKKAEKKNNSETMSEGKKIDRNNTDEKEVKEKVTEKEIKERGGKDESRIQVKDRKKCEEPPRAGFILQTKRNKDSKLRSLSASLDSLLDYTDKDLDESSFEISLFAESLYEMLQYQMGSRIFEFLKKLRVKIVRQRNQRKRHQEELSVKQNEAKSQDKRQKTAEHEDKEASVISESAPGKDDKETSGKETVDGSREIADKEAVAKTKETLGSKEVTVGEAVNMEVENQDEEDDDGDDDPEEDPEEDPEEDPEEDPEEDPEECEEMDVANTEQEEPAEEPQKKEENLEKTSGTVADPITEAETDNRKEERGPNDSKTEIKPKSETEKHGKQDGGTSDAAKREETVDKELLQAFRFFDRNQAGYVRVEDMRVTIHSLGKFLSHREVKELVQSALLESNTGRDDRILYNKLVRLSL
The following text describes a protein:
Function:
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
Subcellular Localization:
Mitochondrion.
Sequence:
MLRFSVLLRRSNLSGCRLWFSTGEPNKEVNTKQVLMELRRKTGYPLITCRQALQASGYNVEKAKEHLLQLAKEKGWNTMQMDGGVLKEGLISVVTNKNNGLIVEVNCQTDFVAKTKEFQSLVKDAAQTLLDVYSTQQPSKIDLNPPELLKLVVSGKKQTIEDTVAITIGKLKEKIEIRRASLLSVPTNSILAVYIHPSVLISKTRPGSTLGSYGAMVSLSPTDENTGKSSIKMAGRDIAQHIVGMNPSCIGTCLKPTPNKSVTDSTPDDDVINPPEMLSPDESSHELLKQPFLLDSSISVAHWLNYHQLNVNDFIRFQVGEKTKSAEK
The following text describes a protein:
Function:
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
Sequence:
MILTGKEIQKRIGNDIVITPYSEKQLNPNSYNLRLHEELLVYTELPLDMKKPNPAEKLVIPESGLLLKPGILYLGRTLESTETHNLVPMLEGRSSIGRLGMLVHVTAGFGDVGFKGFWTLEISVIQPLIVYPGVEVCQIFYHTLEGQITEYTSGKYQANRGIQTSMLYKDFEK