lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MLPALARFGIRGTRTLRPTRCCEYSTEVAAGQSEPTSVPKTTHYRVTLFRSPIGLPKRRHDSLVSLGLRRRMDVSYHRHSPDAAGLILSVKELLKVENVTEEEVELGKQSSRKLVADDRGYRLIRNVLERD
The following text describes a protein:
Function:
Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
Subcellular Localization:
Cytoplasm.
Sequence:
MFTLDDLLIATGGKLVSKGNEIFKEASIDTRTIGKNDLFFALKGSKKDGHEFVDEALIKASGAVVSKNEGMDFKNKTVVIVDDTLKSLQNLAGYLRKKFKGKIIAVVGSNGKTTTKELIASFLSKKYKILKTEGNFNNNIGVPLCISRIENNTEIMVLELGTNRPGDIKELCDIVYPDYALITNIGYEHIEGFGSIQGVREGELEILPYVKTVFANGDDKFLMDGLKRYSGQILTFGMSKECDFRAENINFYNDHVEFDFYSDIAAFAVKTPLVGIYNIYNLTGAIAVATFLGISKCSIQQITESFTSVKMRGEIIKINGVEIFFDAYNANPSSMKVALQELTRRKKGRRTVAVLGDMLELGEFTDLAHEEVGKWVNEMGIDIFIGVGKFIKNALRYVNGYVFNDPIQAAEFLKKELKGSEIVLIKGSRAMKLEKILEILKEGR
The following text describes a protein:
Function:
Catalyzes the aminoacylation of histidyl-tRNA in both the cytoplasm and the mitochondrion.
Subcellular Localization:
Mitochondrion. Cytoplasm.
Sequence:
MFVFTKNLFTTKFSSSLLNWRFLRTMADSLVDINERITSQGNLVRSLKSQGASKEDIDKEVAKLLQLKNLKLGGSEVSGKKKDTSFTLKTPKGTKDWCDKDVVLREHIFSTVTEIFKRHGGVTLDTPVFELKEILSGKYGEDSKLIYDLKDQGGELCSLRYDLTVPFARWLAMNPKVTSIKRFHIAKVYRRDQPAMTKGRMREFYQCDFDIAGNYDPMIPDSEALKVLVEALDALEVGNYTIKLNHRKILDGIFTVCGVPDDKIRTISSAVDKLDKLPWEDVRREMVVEKGLKEEVADKIKEYVLLKGDRSLLDKLEADSLLSSNSSAVAAFNDMRLLFDYLEAFGVLDRFSFDMSLARGLDYYTGIIYEAVTEASAPKIKSSAEKKKSADPEADRSNDDSIGVGSIAAGGRYDNLVGMFAAKKNAKIPCVGISLGLERIFSILRSKIPDEDIRANDVDVFVMAFGGGKEWTGFLKERMSVCKDLWANGIKAEFLYKVKPKPRQQFDAADKFDVPFAVILGQDEFAKGSVRIKQMGLKENSDEGQLVPREEMVSVLKKLLKYD
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MAASARPGERATSFTVACSLLSRFVRQNGAAAAELGLGIKGEVEQQRTPATISLLPGAEGEEAERTKETMELFPQSAGFGVKDAAAPSEQENKEKPKQLTIFYGGKVLVFDDFPADKAKDLMQLASKGSLVVQNVVLPQPSAPAAVTDKAVPAPVISLSAAQADAKKPARTNASDMPIMRKASLHRFLEKRKDRLNAKTPYQTSPSDAAPVKKEPESQAWLGLGPNAVKSNLSLS
The following text describes a protein:
Function:
E5 can induce cellular DNA synthesis. It seems to interact with a 16 kDa cellular protein. E5 seems to activate the PDGF receptor.
Subcellular Localization:
Host membrane; Peripheral membrane protein.
Sequence:
MPNLWFLLFLGLVAAMQLLLLLFLLLFFLVYWDHFECSCTGLPF
The following text describes a protein:
Function:
Dihydroxyacetonephosphate acyltransferase catalyzing the first step in the biosynthesis of plasmalogens, a subset of phospholipids that differ from other glycerolipids by having an alkyl chain attached through a vinyl ether linkage at the sn-1 position of the glycerol backbone, and which unique physical properties have an impact on various aspects of cell signaling and membrane biology.
Subcellular Localization:
Peroxisome membrane; Peripheral membrane protein; Matrix side.
Sequence:
MDRNPVRQSTSSGTVEGESSEQEEQKTPSAAEYMRNFKNIIAPGNEASMTREFNPQVAYEFEKYLNPQKLKQHVLRSEKLRSILEHYAKESGTPLKQMERQARAIIDEIGLDRNMAIIRWCGIAITAIGKRICDGFYVNSASMANVRKDMGKCPVLYLPSHRSYMDFILMSYICYYYDIEIPGIAAGMDFHSMFGMGTMLRKTGAFFMRRSFSNDELYWDIFREYMYALVANYHIGVEFFIEGTRSRNFKALVPKIGLLSMALLPYFTGEVPDVMIVPVSVAYERVLEEQLFVYELLGVPKPKESTKGFFKALKIIDERFGKMFLDFGEPISVKEFFGHDSAQRMQRAGVGGHLQKLNRQEVELVKQLANEIIYQQQRRIVISTFNLLSLYYASQLYAQRSVTLDELARGVLHLKRIFEQLGAHVSTTPSSIKADVIDAVEIHSNILHFATGRLQFTPMAAKQLAEQIDVKRLKAHALCPQTMAVAVPMLALQLYINPCMFWLARPAYLLLAALKEQKNQQKQSTDISYDASLCALHAHVTTMDALFQHEFIIESNREAAEFETHLQLLLDERVVEVETSGRINVQDNECSHVILAALAPFLCLYYQLVVTLRKIPLELEFSNKELLVRVQQHVEQLLQQPGASASHVHPYCLALDNLNIAIYALIQRGYLVKSRDSGQMKIASTPGKCLRELETQLLEYCQLMPFAQYSTAANQQAQFHIAKLXLANGNGPAREATRERDTDSSTDTQSGPNQCSTITISLPMQFIQFVVGLLKNCRIICILFIIVVLSPLWQLLHWIIVSTHSFT
The following text describes a protein:
Function:
Putative transcription activator that may function in lymphoid development and oncogenesis. Binds, in vitro, to double-stranded DNA.
Subcellular Localization:
Nucleus.
Sequence:
MDSFDLALLQEWDLESLCVYEPDRNALRRKERERRNQETQQDDGTFNSSYSLFSEPYKTNKGDELSNRIQNTLGNYDEMKDFLTDRSNQSHLVGVPKPGVPQTPVNKIDEHFVADSRAQNQPSSICSTTTSTPAAVPVQQSKRGTMGWQKAGHPPSDGQQRATQQGSLRTLLGDGVGRQQPRAKQVCNVEVGLQTQERPPAMAAKHSSSGHCVQNFPPSLASKPSLVQQKPTAYVRPMDGQDQAPDESPKLKSSSETSVHCTSYRGVPASKPEPARAKAKLSKFSIPKQGEESRSGETNSCVEEIIREMTWLPPLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDNGTSNTSMLEDDLKLSSDEEENEQQAAQRTALRALSDSAVVQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKVNPHKPPILIQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVSAAAPPPAVPCAPAENAPAPARRSAGKKPTRRTERTSAGDGANCHRPEEPAAADALGTSVVVPPEPTKTRPCGNNRASHRKELRSSVTCEKRRTRGLSRIVPKSKEFIETESSSSSSSSDSDLESEQEEYPLSKAQTVAASASSGNDQRLKEAAANGGSGPRAPVGSINARTTSDIAKELEEQFYTLVPFGRNELLSPLKDSDEIRSLWVKIDLTLLSRIPEHLPQEPGVLSAPATKDSESAPPSHTSDTPAEKALPKSKRKRKCDNEDDYREIKKSQGEKDSSSRLATSTSNTLSANHCNMNINSVAIPINKNEKMLRSPISPLSDASKHKYTSEDLTSSSRPNGNSLFTSASSSKKPKADSQLQPHGGDLTKAAHNNSENIPLHKSRPQTKPWSPGSNGHRDCKRQKLVFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECGNAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPSPWGASGKSTGTPSPMSPNPSPASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLLMGPVTLHSSMEHLVQYSQQGLHWLRNSAHLS
The following text describes a protein:
Function:
Binds together with bS18 to 16S ribosomal RNA.
Sequence:
MRPYEIMVILDPTLDERTVAPSLETFLNVVRKDGGKVEKVDIWGKRRLAYEIAKHAEGIYVVIDVKAAPATVSELDRQLSLNESVLRTKVMRTDKH
The following text describes a protein:
Function:
Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
Subcellular Localization:
Cytoplasm. Nucleus.
Domain:
Folds into a two seven-bladed beta-propeller structure which is required for elongator complex assembly.
Sequence:
MNVSSDVDFISVGCNCLGDCLVWGQNKLAAYGAQNFIALFDPIQSKVLATLPGHKDRVNHICWVPNINEEYKNRYSSYENELLSCSSDNTIISWKQIKGGLNYQYKVVEVLKGHSDSVTNISVLDFPDGSLLMCSTSADNTVKLWRRESLTKENIDTDTLPKWECIQTIDFTPKCMECSSLAFIPGTTIPLLAVGGLEPKIHIYIQNLDSTTATLQFKKLMSLQGHQDWIRSLSFKTINEGEGEGEEEELILASSSQDFKIRLWKISKFTAEKQKQQQLDESGNGGANLLGSLSTQLSGVTSLSTKGYLFNCNSVKYIILLDAVLSGHDDWVYSIHWSPARRDQETGKKIQEQMLISASMDKTAIVWRPDRTTGIWIDESRVGDMGGNILGQYGAVFSPCSQYILSHGYNGAFHFWKQNTNQKSSFWEPQIVVSGHFGPVQDLMWSPDYSYFISCSTDRTLRLFSEWKRNNNNNNLENNKEQQIISWNEIARPQIHGYDLECFTFINKKTHVIVSGAEEKIMRAFVGSQNFVDTLLNISKVQPVNDGTQRPLAANQPSLGLSNKPYFTGGSDYNENIDNNNNNNNNNGNGEENTEDSIKMKMGGGDEGGGGEGMDTGYFEDEIPFNPEVLSEPPFEEHLLQSSLWPEIHKFYGHGNEIVAVACSADGMYLASTCRASSADQATVRIWNVSNWKECANLKGHTLTVVNLSFSHNSKYLLGVSRDRMWTLWERSASNSEEPFVKVISAPKSHGRIIWSGSWSHDDKFFATGARDKLVKVWNLDNIKDIKNACASTLPAFGSGVTCVEFAPKSSKFTGEHGDHLLAVGEDDGKITIWKSTTSTSNPKSLDWTCVHTISPLISHTLDVRRIRWRDTPTINGNSLTYQIVTCSVDHSVRIFNIKFD
The following text describes a protein:
Function:
Has a role in the biogenesis of eye pigment granules. Eye pigment granules are specialized forms of late endosomes or lysosomes. Biogenesis of pigment granules in the eye requires molecular components required for protein delivery to lysosomes (By similarity).
Sequence:
MIMDALRHYGLSQQRTELTSAIQLPLRNTRRIKFTCFDVSEKYIIFGANSGSLYVYDRESVNFLSIIPSQLGTISQVQISSNGKQIAVANMRGAIGVVLDLDGSASKEVLLTELGGGEAAGGVGVVGRSGTTAFVTSFCWGEDDKELYCGDSKGTVSLLQLSMFMGRNILNMTLSPVLLLENHIVQIDRYKELLLVSTLSKCVLCNTQREEFKQIGNRPRDGLYGATFIVPNPEYFNTPTEEDLEDAKSMEGSDDNDNDQRSSPSGVKIAQDQVRIFCSRPGSRLWEADIDGNVLRTHQFRHRSTDREANGPCNEIIAFKLLQKVLGRLILVHDDREIFLIDPIASQVVLWINNVGDISRVRLVGEDIYVFGNDQTMMKLRLDVEQKEVPKRLPKKINGKKSSPFKENGVYILDHLFNNNGLKEGTLQTESTIKEALASVVRGKYGRNIKQMFLGYDQMGPERPKTLNISKVYNSEESYNNMVQVLPTDESSYAEDDCSEDVVPKRNPPKKMFSMSLLSDYQLSEDDKTVRNLYLVYRSSIISNLNFADRYAKIFDAYDTESIVSLLHKLEIVMDENNEEQSRLKCIKIYFDYLKVELIWEIDVESRAFIKQCFIEYNKMLLHEELCELEKCESCGHYLRTNINCHYPEIGTTLIQYYWSRKDYAHCFELVQQIPFLWHTITKFYIQDNREDKAIQCIWNVGDPGLLERAACEMFTMDHWRQLLDLMLTCYNSNSLMCLNCDKLCTLADPGRNPMWREQQNQAQSPVVNPKDNNHINNNNIGITTRGSTNVNRFYSWNYILNTAIDQKCVDGKSMLKLLRGYDEYIPKGAISTSFYLKCLLNVSD
The following text describes a protein:
Function:
Synthesis of fructose 2,6-bisphosphate.
Sequence:
MPVSSDSRGNSVFHGDVNSPGRSLTSSPGSASRLGRAASWHERPNLDSRFPSFHALSETPVSTVPSSPRIKPRLQKKRSVTMSIPGQTFTKLNQSSSASSVEYADDKLVVVMVGLPARGKSYIVNKLVRYYNWLQYSCKAFNAGNLRRKQQAHDSSAAFFDPTVPANARLLDEYASQTLEALIHWLQHENGIVGIFDATNSTLERRKSIVERLQDLPYVTVLFIESVCSDEQLLASNMMLKLRGPDYKGKDPQQSLLDFQNRVRMYEKKYEPLGEKEENLNYRYIKVINVGKKVVAYNIQGFLTGQAVFFLLNFNLSPRQIWLTRHGESEDNVKGRIGGDAPLTPLGLQFREDLAKFIAEQRILFQERLHIAQLQKSDMLQGAAIAAGESSETAATAATSVVAAAAVPSDDFTSDPDHDHDQSNSCYDDGFLKPFSVWSSMMKRSLQTAAAFDEDAYDVKAMKMLDEICSGMCEGMTYKEIRTQYPAEYEARKHDKLQYRYPGSGGESYLDVIYRLQSVIVEIERLQHHVLIIGHRVIMRIILAYFLGCGREDIAYLNVPLHTVYCIEPRPYGTDTYQYNYDPVNRRFVQVPFSVVNKAHDAFEEL
The following text describes a protein:
Function:
Choline transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MGAKISTGEKIQPREFTEKFQRSESEASDDFKTKQRSTTDACFLIFLSLFLTVLLCFLGYCICNGDIFRIINGYDNCGNVCGRYNVIHHGEIRDEVCQESSTWSKPYHIVIRSNDSSVIERKCVSDCNDNGGYRKFFNRCVPVQSTKVVNTFFSKTGIKNFFQEVSEDFHLCWPEFLYLCLIALAFSVLILFLFRYVVGIVVWVVLIGVVLACCIATIILWILWNQSRSNRPEKLISDVDFRKTGTYLAFAIIATVVTVIVILVIIVMRKRIELVVQLFKEAGKAVAAVPLLLLQPILTFLSLAVVITLWFYFCLWIESSGYLTEKKPHVYYYEKDKWMVITRWYNLLAMLWMCQFVIGCQHMVIAGTVSDWYFTRNKDELGTPILKSGYNLVRYHLGSVALGSFLIAIVQFVRVILKCAEKYLHSHRGKCVDYLLKCCHCCLYCFEKILKYMSRNAYIEIAMYGYSFCQAGRQAFRLLVANVLRVTAINSVGDFVLFLGKVLVVAATVLIGTKMLQNKEGLQHMWVPLTLAGLFAYFVAHCFMTVYEMAIDTIFLCFCEDCEQNDGIAKPYYMSRGLMEFVENSKKVLESHDCRQKGSQAWQEKVPSISDSVEKKI
The following text describes a protein:
Function:
Prolyl 3,4-dihydroxylase that catalyzes 3,4-dihydroxylation of 'Pro-61' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency.
Sequence:
MPDHIYSHSFAQFLRNADNSVVNINPYPYVAFEDVFDDTFLRECLKELKSYLTAHFKETDLFKVFQTTDLANLEDCIRDAHTNVPNLIRLREHLYSPGFRGFVSTVTGTGPLDGAVDCSCNIYTSGCHLLCHDDVIGTRKISYIIYLSDPDCDWLAVDGGQLELYASDRRTVPTHTPVVSILPSWNSMVMFEVSPGRSFHAVREVSAEMKTRVSISGWFHTKERHIKRNQRETSTLDQLHSMIPATHAEWAVLHVNRVLSPSYSLVQDLTKWINPEYLRSESVKRVRQVFEADGSVQLFNFLLPHIAEPIKRKLNREDCRNSRHRCMYDHGYGDSWVVQGPPHVQRYLSYQPLECTLANKRSNSGELLKKLMCDLFESSSFQNWVRAVTGSVCDLAHSEVRRFRPGFDYTLAHAGTKRCSSEIDVTLCLTSGPNPAEWLSGDLGGFKCFIPIGSKSDRADVYEEIGEEQNMRSVTPSFNCLSLVKVNTGIGDFVKYVSTSAKSSRWDIVCRYST
The following text describes a protein:
Function:
Member of the two-component regulatory system NodV/NodW probably involved in the regulation of the transcription of genes involved in the nodulation process. NodV may function as a membrane-associated protein kinase that phosphorylates NodW in response to environmental signals.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MYRISSFKRSAPQLTLGSIALAAVTLTCVYFQAHFAAAAFAYLLVVLLFSLMGSFIASSALCIVAIAALAYYFAPPAFSLRIDDPRDVPVVVAFLIVSVVGTYLIGKLRQEREAARVAAAKLQRSASDLEDREKRWRAIFEHNPAMYFMVDEAGIVLNVNTLGATQLGFACAELLGQSVLDVFLEEDRAFVRKCIQTCLEDVGQSRTWDVRKVRKDGSVLWVRENAKAMLWAGDRPVILMACEDITERKQTELALQRSEAHLAHAQELSHTGSFSWNASTGEAFWSKETFRIFQIDLQTTPAPQLVIERTHPDDRASVKEIIDEAMRDLRDFEHEYRLLLPDGSVKHIHAQARVTRTASGEIEFVGAATDITAARRAEQQLRRSEAYLAEAQHLTHTGSWSWDVHTRDFVYRSAEVDRLFGFNPQEPVSLETIRSRIHPEDLPGLQEVQRQAIDQEHERFEYDFRVILPDGGIRRIHSVAHVVVGSDGNVSELIGTHMDVTEQHAARERLENTLVALRESEQRFRDYAETASDWLWETGPDHRVTHLSEHTSAAGILATGLTGLLRWDIACDMEEEPEKWRQHRATLQAHLPFRDLIYRTVNRMGSPIYVRTSGKPFFDGNGNFLGYRGVSTDITATIRADQAEQELRKAQAELAHVTRVTTLGEMTTSIAHEITQPLAAILSNADACLGWMARDVPNLAAARSSVEWIIEDAIRASEVIRSIRALAKKGEIEMVPLDINQVVRDVSALVTRELVSHQVTLRSELASALPRVLGDRIQLQQVIINLVMNGIEAMDAVTDRPRELLIQSSTDDLGYVQLSVTDCGVGIAENDADRVLDPFFTTKSSGLGMGLSICRSIVEVHGGRISVVQKNGPGATFQFALPLHKEAIS
The following text describes a protein:
Function:
Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. Binds to pericelluar hyaluronan matrices deposited on the surface of leukocytes and facilitates cell adhesion and migration through lymphatic endothelium.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MTSITGYTIVLLSILLTRFVVHCVIPIKDLAHSPCRFAGVLLAESSEHKYKFNFTTAESVCRVLGLQLASKDQVEKANKYGFETCSFGWVLERIVVISRIQSNEKCGQNKTGLVPWSIVNTDQKFHAYCFNASDTWKNSCKPDPLTTLLPDTSMAPSSTAESVQSSAYDTTTETISVLNKIMSTHGYVKTTLFLPPFTATQLTATQLTATQLTATQLTATQLTATFINDLLEKSTNKAEAVNAKXRFGGLPAALLTLVLIFFIASVVLAVCYIKQYKVTKWLFTKKEERESVETKEFKENTNTEQESTKEEGKMANKKSEVPQGCTGNSMEAEV
The following text describes a protein:
Function:
Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools.
Sequence:
MSLFDLFRGFFGFPGPRSHRDPFFGGMTRDEDDDEEEEEEGGSWGRGNPRFHSPQHPPEEFGFGFSFSPGGGIRFHDNFGFDDLNFQVLSQRHLVRDYGRDRHFGTQCLSIQIVTSPGSLGGSWRVMQEVNPPNQHQTGAPRGHFIGLMMYGLWTPILEPERTMFLPVHLSPFFLWTLSLLLLHLSALPDLDSQVSQEGLGPVLQPQPKSYFKSISVTKITKPDGIVEERRTVVDSEGRTETTVTRHEADSSPRGDPESPRPPALDDAFSILDLFLGRWFRSR
The following text describes a protein:
Function:
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene.
Subcellular Localization:
Nucleus.
Sequence:
MRKRTDSPPLGWELRPGRAYPVAAPSKCAGPTSATRSHETPLGSSTPHASCLDLWRQRNDQLVRQAKVAQGLSLRRQQLAQDALEGFRELLHCLQVLETQEQLEPRLECGLSALWDSVLHSSSLLPELLPALHHLAALQAALWLTTDHLGDLTLLLQTLNGSQSGASEDLLLLLKTWNLPAEESDAPLTIQDARGLRDVLLTASAYRQGLQELITGRLSRALSSLHEAASGLCPQPVLVQVYTALGTCLSKMGNPQRALLYLLSALKGGSTWGPALLEASRLYRQLGNTAAELESLELLVETLSITHGSEAPQLLIEVELLLPRPEPASPLYCGTQSQAKYLLASRCLQTGRAEDAAEHYLDLLALLLDGSEPKISPPPCPTGPCMPEVFLEAAAALIRAGRAQDALTVCEELLSRMSSLLPKMPQPWGNARKGTKESPHCPPWVSATHLLRGQAWVQLGAQKEAISEFSRCLELLFRATPTDKEQGPASNCEQGCTSDVALQQLRAAALISRGLGWVTSGQDTKALQDFLLSVQMCPGNQDASFHLLQTLRRLDRRDEAIALWRRLEAQTKLPQENATWSLPLYLETCLSWICPHDRETLLEEFQTSLLEPCDL
The following text describes a protein:
Function:
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Subcellular Localization:
Cytoplasm.
Sequence:
MSLAEAKKLDKKFPTFKNEFAIPTFGSLGIKNNKYESSTESIYLCGNSLGLMPKNTKKAINDELNAWVERGVESHFNHPDKSLTPWVDIDLPLLPLIAPIVGAKENEVAVMGSLTANLNALLIHFYKPEGKRTKILFEKQAFPSDYYAFLNIVKLFGYDEKHLIQLEVQPGETYIKTERIIKAIDENSDELALVCFPGIQYYTGQFFKIEEITKYAKEKSQQIKVGWDLAHAVGNVPLNLHDWGVDFAAWCSYKYLNSGPGAIGGIFVHEKYTIENKKSSFVPRLAGWWGNNSQERFKMLEEFDPINSALSYRQSNPSVLDVVAVKSSLEVYAKVGGVSKLREKSVALTQFLQDLLTNSKYYIPQSSTSNSKFGFKILTPLNPAERGCQLSIMFQPHFDEKDKNVMERVNAYLHDHAIICDERRPDVIRLAPLPLYNTFEETFIAVQRLFEALDNISKEYM
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MGIAVAGMDSLSDRASMMREALQKSQTITDNVVSILGSFDSRLSALETAMRPTQIRTHAIRKAHENIDKSLKSAEVILAQFDLSRQAEAKILKGPHEDLEGYLGAIDQLRSNIRFFSSNKNFKNSEGVINHSNTLLAKAISKLEDEFKQRLNSYSKPIEPDRLFDGLPNSLRPSSGSPGNQGEPGGRGPSHNHSEHQNVDLETAVYTPPTLIPPRIMPLLHDLAKQMVRAGHNQQLLKIYKETRSLVLEESLRKLGVEKLGKDDVQKMQWEVLEAKIGNWIHFMRIAVKLLFAGERKVCDEMFEGFDSLSDQCXAEVTASSVSVLLSFGEAIARSKRSPEKLFVLLDMYEIMRELHSEIETIFKGKACNEIRESALGLTKRLAQTAQETFGDFEEAVEKDATKTAVLDGTVHPLTSYVINYVKFLFDYQSTLTQLFQEFETGDGTVSQLASVTMRIMQALQTNLDGKSKQYRDPALTHLFLMNNIHYMVRSVRRSEAKDLLGDDWVQRHRRIVQQHANQYKRNAWQKILQCLSIQGLTSSGGGSSVGDGGNSSGVSRALIKDRFKIFNMQFEELHQRQSQWTVPDTELRESLRLAVAEVLLPAYRSFLKRFGPLVENGKNPQKYVKYTAEDLERMLGEFFEGKNINEPKR
The following text describes a protein:
Function:
Cadherins are calcium-dependent cell adhesion proteins.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MPERLAEMLLDLWTPLIILWITLPPCIYMAPMNQSQVLMSGSPLEINSLGEEQRILNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSGDGAGTIFQINDVTGDIHAIKRLDREEKAEYTLTAQAVDWETSKPLEPPSEFIIKVQDINDNAPEFLNGPYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQPYFSIEPETGLYHFSVPEDVVLGTAIGRVKANDQDIGENAQSSYDIIDGDGTALFEITSDAQAQDGIIRLRKPLDFETKKSYTLKVEAANVHIDPRFSGRGPFKDTATVKIVVEDADEPPVFSSPTYLLEVHENAALNSVIGQVTARDPDITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDRELSVWHNITIIATEIRNHSQISRVPVAIKVLDVNDNAPEFASEYEAFLCENGKPGQVIQTVSAMDKDDPKNGHYFLYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLLPIIISDSGNPPLSSTSTLTIRVCGCSNDGVVQSCNVEAYVLPIGLSMGALIAILACIILLLVIVVLFVTLRRHKNEPLIIKDDEDVRENIIRYDDEGGGEEDTEAFDIATLQNPDGINGFLPRKDIKPDLQFMPRQGLAPVPNGVDVDEFINVRLHEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESTTSDSDQNFDYLSDWGPRFKRLGELYSVGESDKET
The following text describes a protein:
Function:
Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids (By similarity).
Subcellular Localization:
Lysosome.
Sequence:
MSAPDILKDFKGSLTIEQDGSISSASGILQESFYNNKEFASTIISMLHDVNKITSSNNQEFKRMTVSFSEQTFIVTAIGTKIYVVVQ
The following text describes a protein:
Function:
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and directs ubiquitination of phosphorylated CLN1, CLN2 and GIC2. Probably constitutes the primary response element required for the generation or interpretation of the signal that induces glucose repression.
Subcellular Localization:
Membrane. Note=Associated with the particulate fraction. Probably forms a complex by protein-protein interactions via its leucine-rich segment.
Sequence:
MDQDNNNHNDSNRLHPPDIHPNLGPQLWLNSSGDFDDNNNNNNNNNNNNSTRPQMPSRTRETATSERNASEVRDATLNNIFRFDSIQRETLLPTNNGQPLNQNFSLTFQPQQQTNALNGIDINTVNTNLMNGVNVQIDQLNRLLPNLPEEERKQIHEFKLIVGKKIQEFLVVIEKRRKKILNEIELDNLKLKELRIDNSPQAISYLHKLQRMRLRALETENMEIRNLRLKILTIIEEYKKSLYAYCHSKLRGQQVENPTDNFIIWINSIDTTESSDLKEGLQDLSRYSRQFINNVLSNPSNQNICTSVTRRSPVFALNMLPSEILHLILDKLNQKYDIVKFLTVSKLWAEIIVKILYYRPHINKKSQLDLFLRTMKLTSEETVFNYRLMIKRLNFSFVGDYMHDTELNYFVGCKNLERLTLVFCKHITSVPISAVLRGCKFLQSVDITGIRDVSDDVFDTLATYCPRVQGFYVPQARNVTFDSLRNFIVHSPMLKRIKITANNNMNDELVELLANKCPLLVEVDITLSPNVTDSSLLKLLTRLVQLREFRITHNTNITDNLFQELSKVVDDMPSLRLIDLSGCENITDKTIESIVNLAPKLRNVFLGKCSRITDASLFQLSKLGKNLQTVHFGHCFNITDNGVRALFHSCTRIQYVDFACCTNLTNRTLYELADLPKLKRIGLVKCTQMTDEGLLNMVSLRGRNDTLERVHLSYCSNLTIYPIYELLMSCPRLSHLSLTAVPSFLRPDITMYCRPAPSDFSENQRQIFCVFSGKGVHKLRHYLVNLTSPAFGPHVDVNDVLTKYIRSKNLIFNGETLEDALRRIITDLNQDSAAIIAATGLNQINGLNNDFLFQNINFERIDEVFSWYLNTFDGIRMSSEEVNSLLLQVNKTFCEDPFSDVDDDQDYVVAPGVNREINSEMCHIVRKFHELNDHIDDFEVNVASLVRVQFQFTGFLLHEMTQTYMQMIELNRQICLVQKTVQESGNIDYQKGLLIWRLLFIDKFIMVVQKYKLSTVVLRLYLKDNITLLTRQRELLIAHQRSAWNNNNDNDANRNANNIVNIVSDAGANDTSNNETNNGNDDNETENPNFWRQFGNRMQISPDQMRNLQMGLRNQNMVRNNNNNTIDESMPDTAIDSQMDEASGTPDEDML
The following text describes a protein:
Function:
Stimulates the exchange of Rho1 GDP-bound form into GTP-bound form. Regulates, via interaction and activation of Rho1, beta-1,3-glucan biosynthesis and cell wall integrity during septation. Involved in the regulation of contractile ring assembly.
Subcellular Localization:
Cytoplasm. Note=Localizes to the outer area (150 nm) of the contractile ring.
Sequence:
MKLSNELFHRSSKDHGGKSRICLDSSEDTYPPHSSSPPSFQKRLSFSDFSTTRLFSPPFLSKRSNNSPHRFSYSPPQHPASINSRRVASYTVQSSPSRTTYRQLPNEPQNSAAYTTYSSFPNALFDDFSPNNPLDTDPFLTSPGNKQNTVDSFRPLPETPVSPGGSLVHPLPRPPLPSSVSSHSSPYSTTSSTSLYSLYNDISLSCSPEPYLPLSPTRSPARTPSPIRLYSSDALRPQSPLSPSVEYLTPPNPYSLKSDISSTRQLPKIPVQDYASGKISSPLITRTHRRAQSETLFSSCREPWLVGKLYKWCKEEVFTALGGLVHEGVSRREVAQVMATLFTIHIASMEFLIAEIIAKNILGDWINYGLVEVINLEKLQIAFTSNEPPSGSGVLPFLTNGGCYSYICRSRSCPSKYQCYSCRCARNSSLEFTSLPGQSSDTWSIFWNISSLNSLPSSLSKREIARQNNIHELICKESDYVADLNTLAELFRDGIVQQQDAIVPSNRVADFIQSVFGNVESIRQLHSRLFLPQLIMRERLQGPVVSIIGDILLEWIHAAKSSYINYAKQFPLADETYKLECQRNTYFARWLAACRSDPRCRRLDFQHFLQRPTQRLQRYTLELDTILKHTEQSSWDFQLITQAVKELRATCEECDAVIATVLEANRIRDLSYQLLFKNHESVNLELRDPEREFFFEGIVQRRSDSRLDWLDIHLFLLDNYLIMAKARKDKRTNASRYVVSKRPIPLDLLVLSPKMDDFQLKSNTNKFLGSLAGNLPQESLTTKSKRKSKVNLELMFDATAEKNNENSMNSAVFEKSQLYPFTIRHLGAYTASYTLYVESLQLRKLWVEKINVAKKRHSQKINIKNPFALKVVSDVAFQYPPSDLVNGNEPLNSFNEITLVEGSSIDRALNEVAWKHPIVSEELLPEPIAYGDISCIAQFNDYEGHVSVLIATSTGIFLGAFGDSSDIRDWKKISSQRRVTQLGVVEEFDILLELRDKTLYAHKLSRIIEMGLIESKIAVVIGTPHAVSFFKIGKLSEGASVKRERTLVFYKEGLGNTTTIICCEPVIGLGHNYQKTYAFKRKDVTSFRTLDDFHVTANCHSIDCFKYSIALCHNKGIDVLRLDPKLAVGFPSPSVLNDTLFRNRINNSKPLGVFRIHDPSLFACCYQFGAVFVNGEGSMVNKECWFDWIGKPNSVTSCHGYLIAFNDEFVEIWNTRTRKLNQIIQGNDIKYYPSNSDWLANGKYIMFGMVHPQYHDRHLILALNKAKTNSFIIED
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MSLTHFRPSPLLRPSLVLSQPLIPRTSQSTYATHSDLGRGSASAPRRRNVTVLSDDGRYTWSELSGREKVARATQQSINFVVVLAGAALTVNTIASRKTWQFEKAVERIKNDARFANLIAGSTTIEKDHQGREHMRMNFHVSGPRNSGTVFVHMVKPTDANEWEYRLLALEVKGYSRVVLEERHDPKVGGEVKIFGIRWR
The following text describes a protein:
Function:
Member of the two-component regulatory system CrdR/CrdS that induces the transcriptional induction of the copper resistance determinant CrdA in response to increasing concentrations of copper ions. Functions as a sensor protein kinase that phosphorylates CrdR (Probable). In turn, CrdR functions as a transcriptional regulator by direct binding to promoter regions of target genes including the crdA promoter or nitric oxide-responsive gene promoters.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAIALTHYEKKSLKLFLGIYLGSSFVLMLVISVLAFNYEKNEKIKMIRMDMDKMASKIASEVIALHMQTHGDYQNALNALISRYKDASIALFDSKKRVLYSNIPESANLIKNHKEAGFFSFRGEYYLLSDETFAHLGVAKMLFKNSKPLHFSSLYRNIVLVFVVAFLCVIGVSVFLGRLFLKPIRNEITRIDHFLKNTTHELNTPMSALVLSLKTLEDNQQHRRIKIAIQRMSFLYRSLSYLVMQDIERESFVLLDLKALIIKENTLFSEMIDYHKLEFKSDLVEVELKAKEQDFISLYSNLLMNAIKYSVMNGYIHIELTHAFLKVKNLGYEIPKDKITELSVRYVRFNSGVLGYGIGLGLVKKVCEKYKMRLEIHSEPSLKGSFYENSFCVQFQG
The following text describes a protein:
Function:
VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MLKTIIGTIVLLIPQPALSNSAADENRGPFTALCTLVNLAKQPPAQLQAPADIAATLETIAAINMTVADSTFMDKVDVNKDYATADQPFRDARPGWEKNYALFSKAKRKATGDEKAKFASWAAKKGIPNLKQQVIKLAEAAQKIGADAEAAASRLATGKVEELLNKALYGTAAPTDTSYKLATDTADNRAKLCSQKGGKGKSIPGKSLVHDLICLCARGPNSDASQGKACCGDCDGNLATEVAVNSDAKTQIDALTKACSKLGSPTELTRATLTGAVAALANQLQHKTATQSSENNVLGTMHSDGSAGCTGNAASNGGKCVVYKDGLTSSGDNAVQWLKHLQEAISEEARRHAASQKLQTLATQIKLLNITLAALEHGTTAQEHVAAEDKPKAADSTDKNKECNKAKDDKEKCNELKEKGCVFNETGEANKKCQFNETKASKNGVPVTQTQTAGSTEATAVNCGQHNEKTKCEEENKGKSSPVCGWRKGKEGEPEQDKEMCRSSSFLLNNKFALSMVSAAFMALLF
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Nucleus. Chromosome, centromere, kinetochore.
Sequence:
MSTMFEPSLSTSMSSSMMRPPLSSADAPSMADTLPSINFGFDELRDRMAKFTVKFDAFIEQGRKRVLEERNQFRMNVTELHEDQRMKKRDIEVLSSKASTHQQTLAKEAAETAEMQVAIASLTAQRDAQLATREALKSQIAETQKAINARVAAQKSHAQYIDKQARFNVPELDFWISNLGLMIEGAGQNDRLKFIFMNIDDNDYDREAWFELDTSKRDYDIPYCKPKLEKEHIERVVDKLNETRDLRVLLKGMRELFVEAIKN