lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Probably part of the ABC transporter DppBCDE involved in dipeptide transport.
Subcellular Localization:
Cell membrane; Lipid-anchor.
Sequence:
MKRVKKLWGMGLALGLSFALMGCTANEQAGKEGSHDKAKTSGEKVLYVNNENEPTSFDPPIGFNNVSWQPLNNIMEGLTRLGKDHEPEPAMAEKWSVSKDNKTYTFTIRENAKWTNGDPVTAGDFEYAWKRMLDPKKGASSAFLGYFIEGGEAYNSGKGKKDDVKVTAKDDRTLEVTLEAPQKYFLSVVSNPAYFPVNEKVDKDNPKWFAESDTFVGNGPFKLTEWKHDDSITMEKSDTYWDKDTVKLDKVKWAMVSDRNTDYQMFQSGELDTAYVPAELSDQLLDQDNVNIVDQAGLYFYRFNVNMEPFQNENIRKAFAMAVDQEEIVKYVTKNNEKPAHAFVSPGFTQPDGKDFREAGGDLIKPNESKAKQLLEKGMKEENYNKLPAITLTYSTKPEHKKIAEAIQQKLKNSLGVDVKLANMEWNVFLEDQKALKFQFSQSSFLPDYADPISFLEAFQTGNSMNRTGWANKEYDQLIKQAKNEADEKTRFSLMHQAEELLINEAPIIPVYFYNQVHLQNEQVKGIVRHPVGYIDLKWADKN
The following text describes a protein:
Function:
Mediates both low-affinity uptake and efflux of sugar across the membrane.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Sequence:
MEDEKNENLMTFIQFCATFITITLFIMPLKTIRLIIEKKNVGTVAGLQFISSVLNCFLWISYALLTSNTTMLFVNSIGMMFSIYYVFNYWKNINQVRASRDYLKKVMIACVLAITIISISYYNTVDDLDTRISRLGFLSSVVCVLMFASPLEKMAIVIQSKNSEGMIINVAILSLLCGLSWTIFGLLLNDIYIYLPNILASILSFVQLTLIKLYPPQILL
The following text describes a protein:
Function:
Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MGSLFRSESMCLAQLFLQSGTAYECLSALGEKGLVQFRDLNQNVSSFQRKFVGEVKRCEELERILVYLVQEITRADIPLPEGEASPPAPPVKHVLEMQEQLQKLEVELREVTKNKEKLRKNLLELVEYTHMLRVTKTFLKRNVEFEPTYEEFPALESDSLLDYSCMQRLGAKLGFVSGLIQQGKVEAFERMLWRACKGYTIVTYAELDEALEDPETGEVIKWYVFLISFWGEQIGHKVKKICDCYHCHIYPYPNTAEERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVCSRVIQVRKMKAIYHMLNMCSFDVTNKCLIAEVWCPEVDLPGLRRALEEGSRESGATIPSFMNTIPTKETPPTLIRTNKFTEGFQNIVDAYGVGSYREVNPALFTIITFPFLFGVMFGDLGHGFVMFLFALLLVLNENHPRLSQSQEILRMFFDGRYILLLMGLFSVYTGLIYNDCFSKSLNLFGSGWNVSAMYSSSHSPEEQRKMVLWNDSTIRHSRTLQLDPNIPGVFRGPYPFGIDPIWNLATNRLTFLNSFKMKMSVILGIFHMTFGVILGIFNHLHFRKKFNIYLVSVPEILFMLCIFGYLIFMIIYKWLAYSAETSREAPSILIEFINMFLFPSSETHGLYPGQAHVQKVLLALTVLAVPVLFLGKPLFLLWLHNGRSCFGVSRSGYTLVRKDSEEEVSLLGSQDIEEGNNRMEEGCREMTCEEFNFGEILMTQAIHSIEYCLGCISNTASYLRLWALSLAHAQLSDVLWAMLMRVGLRVDNTYGVLLLLPVMTFFAVLTVFILLVMEGLSAFLHAIRLHWVEFQNKFYVGAGTKFVPFSFSLLSSKFSKDDSIA
The following text describes a protein:
Function:
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
Sequence:
MFKQKSFSKIIPLLDKTRHKGQNGKIASIGGSFEYTGAPYYAAISALKGGGDLAYIFCTKSAAIPIKSYSPECIVYPYLLEEGEYVLLENAVNKLVSSTSIMHSLVIGPGLGREQITGRMLENLFQKNNSIKILDADALWHISQKPNKLIAIIQEKSDQFILTPNAMEVKRLLEYFDIQYIKPDYDSLNVINDQDVNYKQIGIENGYPGLIAELSRKLNNVIIVSKGQNDIITNGKVGYAVNLQGSQKRCGGQGDILSGLIGLYSYWSQEQEVDKIEGCILGSVVTRRAANLASNKEHYSLTTPKIIDHIGEALYSIVTDQ
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase.
Subcellular Localization:
Endomembrane system. Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Domain:
The RING-type zinc finger domain is responsible for E3 ligase activity.
Sequence:
MKSGPPAHIHTQGGRRTEVDPQLRICCDLVMTELTEEKTWLADKLQHCIGDDIFGVPDGATAACWDCSICLETATEPVVTLCGHLYCWPCIFRWLTTSSKSKSRASSSARCPVCKAAVSEDHLVPLYGRAAATLSPAGGRGGRVCQVPRGLPVPGAGPNVERLQEPDLHDGGNFYYYENIGINGLDCSNAERLLGGIALAVLLPWATRGGGRPPPPSLYRDGEGWRMARQQRRVARRLWQLWVFLAMVAFLCFLLL
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Nucleus.
Sequence:
MTLCLTDLPTEDIDDLKICNQKKDHKDNRWRRKLSPRHTGYTSQFNENFNTEAVSAHVNSFNDFIDSLNTTIIKHAPAIVINLSTSKAIKVEIVNLTIKPPSFTPAFARETRANYCGPLHVTLKVSDGPMSKTVVINAGDVPVMVGSKLCLLHGKTREERIRLREDERDAGGYFISNGQDKVVRLYLDCLSNTPLAFTKYRSLSTISEFAPAGVHYKGVREDGHVYSTVIQARKDNFLSVKFTIDGRYIYVPLILVLRALVSTTDKEIYSTICTICASAHPKEDGYVSLRVEAMLRDFHKYRIFSHKACKQLLGGKFRMILSLLDRYDLTDVDCCDLLFEQYLLINIPKEDTRAKFNMMCLMARKCLLLFGSFIKPDSPDLLSSQEALTPGAFFKAEVTSTLIKIMRLVSRNATSTGAIGSYELSNSWISHYIASPKLWRPLSSGLRSLAGPGVMRAYKGHDYSNMSGLSVLADRINYVRFLAHFRCINRGNAFATHKITSIRKLYPESYGFQCAVHTPDGAPCGILTHLCYKATVLSSTPTTDQIANLFILLAQFGLSPSLSDIYSLCVVLNGTILGYLDTNERAIQLVACIRAAKVKSIIFPYTEVVFIEKGNKDHLFPGIYMNTSMGRFYRPVHSLTNNSPEYITPLEQIFLQIAIYGDDVRLGVTTHQEITPTSLLSILGLLVPFSDHNQSPRNMYECQMLKQTMGIPCRNLAYKYDTKSYLLTTPQKPLVRNAIIHDIGGFDTHPTGTNLVVAVSAYTSYDMEDAALINKASLERGLFHGTVYSVHDIDCYDDKLMRYMRTVATAVPYLKRSPDYIVTHMDENYDTELDEDGLPPVGAYLSHGSVFYQTYDPTKQCYSTKLYHHEPGFVEKVIVIHKSAAKGEYWTDNDIATKKKRDSSFPAGDSNSSNLDNDASDDEISNQPGSGSESNEDNQTATPRSHASKAERKSSRQLQTRARTESSSLHFIQRVRIVIRHDRTPVVGDKVASRHGQKGIMGIRWRQTDMPFTSSGIVPDLIINPHAFPSRMTVGMLIESLASKIGVHYADFVDSSPFQWSDERRAIDVFGEQLLKTGQFNRYGSEVMYSAITGDPMPADIFIGVVYYQRLRHMVSDKYQVRAEGPSDKITKQPIKGRKRGGGLRFGEMERDALLAHGAMASLRGRLCTESDATEHVVCAACGSLLGMQLGGSVCRECKATGHGRLIQIPMVLLVLANDLAAMGVRMRFNVSLVE
The following text describes a protein:
Function:
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
Sequence:
MANFNKGPAYGLSAEVKNKIAQKYDPQVEEELRLWIEEVTGMIIGENFQQGLRDGIILCNLINKLQPGSIKKINEAKLNWHKLENIGNFIKAMQDYGMKPHDIFEANDLFENGNMTQVQTSLVSLAGLAKTRGFHTSVDIGVKYAEKQKRQFGDEKMKAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMPAPGTRRDIYDQKAILQPVDNSTISLQMGTNKVASQKGMSVYGLGRQVYDPKYCAAPTEPIIHNGSQGTGTNGSEISDSDYQAEYPDEYQGEYPDDYPRDYHGQYSDQGIDY
The following text describes a protein:
Function:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MATRQPYQKKFQSRDQREQTSSQQAPNSVVKQVTVDALVVMKIIKHARENPHEPVRGPLLGLSQLADASKPGEDALLEVTNCFPTPRVSDDDDDSIVQQYQVQMMRWLREVNVDHMNVGWYQAADMGTFFDEDVAAVQFQHQRHMAESVVLIYDPVLTLQGTLSLSAFRLSNKAMELFSTDSFNPKAVREAGLTYRTVFEKVPVTIRASSMARLLIPELSANLDQSEIFDRMDLNATSFMSRNIKLLMEGIDDLSQEAYKFQQYHRNATKAKASLDAQLEARRAENEQLRAKGLPEKSEAELVANHKTPTPPSRLGSLLVTAQINTFCKQVSDFSGQSFGKLYIAKATQPEAEE
The following text describes a protein:
Function:
tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Sequence:
MDELEVAILCLYGNEHSNINKNDAQKYCENFQNSADCWKYCMSKFLESNKLEVKFFCIHVIVEKISTLKIEDMILIKNSLYGYIEKKYVNANEDSCVLNKIIQLYLYLIEFLYPHNMNDAFKYLINLIMLNNDINIKTIHINFFLKLMNMFDSEYIDNVCSNKSIQTTTNIKEAIKENDLPIIIECFYYIMNMNIPESTSLSIFTLSKYVPWIDINYVVNDKILTYIYQTLNTTNSITEASYSFLTSLIRKGMNSANKIQFIESINIICILQNTPKITDLTFDVNKNIMTKRGELINYICLELVESIFEINKLKDYQMNMLKYNEICTKAADMLFLVLPHALDIFSVNDFYIASTVEKFFSLFFTKFKNVIDVGSCANSIMKSSSNDYESSKNNISNNINSSINSNINNNNANSGYKISIDKLNVFINTLICTIVNKFEYPECIPDDYDEEEEDDDEFSTFFNFRENIEKLYQRLILFDKLKAIEIIKNAIIYLNENYDNLKWNNIESKLYAFYVTTSIYCEYKQGSTNTSNNLNNNMITNNQNKNNIIMNNSLEHFKNIKEANEVNIDYNNLLFDCLIELLKNRKILNSTNYHININLMEIFQRLNLFFIKNPNYIEYALHIFLTNGIRSNNNKIAKKSVHIFKKFLKTNSSVISNYIKDILQLLESYLDVPYIYPKMDINNNILNNNNMILDDNTIKYIYTFLYSNKNYNHEYQIDIYEIIGLLLLNYDFNKFKKLSKTDSGMSIQSNNNLSNNLNLNNNDNSININNNNNNNTINSSNNNSNDGLNQNISEEMIANYKDRIFFFKGILNKLLENLSAVKNLYLNSTKTQHDNICASFISSVIIKCIGALCKNVNINITDILLNDLDNTLGIIISESLELFYNNYIVRDSVLFTYRILSNLFKDLSLNYTVKILPYFYNISYNMIMNKLQKSSVDNQNANTFNMITPTSYQSVDGTTNNPMKTSNTHHEELKYLYNELNELSILVCHLISTHKEKSFDTFVNPYIYNITQIHMNIWKFINVQSLEMQREQNAVLSPLLLILYNISVNIPATIHSFMSFEHIALNHKQFCDIFSNDDIIKSKIADAITSILLISLNYKNTSDINICLYSAQTLSNMLNNATCMTNPSEVLSKYPIMQIIDTLCVTLKSLDYADPKTKRIMQEVMNIFRLFCGFKVSANCLPNKIIESSQICLQNSLLSVFKNNPNDIAILIQAINANNQQQFRQILSNIVA
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It probably triggers the ubiquitin-mediated degradation of different substrates.
Sequence:
MGGRNGSLRCSNRLRKRRIILHLETASREESSTGTGSRSTARRARREIDRPSIMAKKAGADRTAAAVKAGSCSRKKAKAASSSKITVTLDPKLLECSVCCSPLVAPLSQCANGHITCFECSSDVNYSCSLCSGPANTHCSALERILAGLAVPCSFQEHGCTEMIPFTEKLAHEESCLHAPCHCPIAGCCPYPGRSLHDHIKGEHPMIQYTRITAGRLYPLSMRHDELARLVSLGSKAVFLLVVDRSVPSGLTLSVIHLMSDPIEREDFKYKIQVHTQTGILSLSGETQSVGRLRGPYQAGASLFVSDTMWSPPDSPVYLELKC
The following text describes a protein:
Function:
Binds DNA as a heterodimer with MAX and represses transcription. Binds to the canonical E box sequence 5'-CACGTG-3' and, with higher affinity, to 5'-CACGCG-3'.
Subcellular Localization:
Nucleus.
Sequence:
MYSDDKRFPSRTQPGVAFGDPSVQPGVGALSEMDKCFPYSILTKKHPLGGGSGGTGGSLAKPSVPPTVPSYLGLQREPSANATKPEAAFDPSGTSDVNNFYGSAMVTDVGICFSMSNVNLNGHPPTIPLATGALVPPAAVAAQSRPSALAAPDARRKSYEDPGPETALLNARRRAAAFLPVTANGGRAAGPGAHASMHHHHQQRRPQAFPFPAATVYPLAHHPPGTVAAPFPQPLANVHPPVHQPLPRQRSVGPVGKGAYGSVRSTSSDRGRGGGTGGSPSMVPTIGTLGGIGTLRSSPPYPKQPPGAATKPSAVSYYQPLPTIGGPGTVQAQPSYGHPLAGAATSQSTPAGPPPPPPPVGYHHQRGNVLPYHHLPLANGVPLTGPAAASPATAAAAAAVAAAAASYEYYRYAIEAAESVGKLPPSGSAQSVLLPTGTMAATAARTAGEDGSKGASGTASGPVVDYNGLRQLFLKCCYNEMKLLPASGAPAHPSAPVLSSPTVGCVSAPTSTATSLSADSPVHSYDFEPQDPRAAGRDAPVVYPSGQQQQQQHHQHHYHQPLTSRSCPSSPNGPHCHTSPALPTLAPSACSTPIGSGRLSAQQQQQLHQHDRYEASEDEVRPMEVCSEDGQEEPIEPEECCSDEPKDFSMKSKALPVGHGGVWPAAAQRDECAIGPQRIEDRSRKEIKAAPKKKWIHRHYMKDEPLTNGHSTAPPLVVIATNGTQQHPAAKHHLTLNHVAVPIAPSSIPAGAPTTITTTSPSPMTIDLSTKGLSQHQQTSTTHYAAAAVHPSPLSTTPPATTTTVSSLSSSSSSSSSSSSSSSSSSSPSSTTLTVSPVDDSQSSLNLSNGSSINGYITSSSSSSSSNSSGATGAPIGGTSPLPPGLAGMLPINITNVLQASAIAAAHNGGTGSSTPNGTIVTAAAATGVHHLPLELQQQVATGLSVAAISSQGAQGLFANIPTGTRRRTTSSNSNGVGTREVHNKLEKNRRAHLKECFEQLKKQLSLQPDEKKISNLSILHAAIRHIQLLKRKEREYEHEMERLAKEKIASQNRILVLKRELTQMGDIDVSRLAPDTDITPNPTNGGTVVPPNGLQMERDQPSDTIPGRNGIRYSSSSSLSSIATNASISNLPLQTTISPVLSVSSPSRASPALNRSSTSPASSLSSASPSSSAASSLSVSSTAAASLMAPLSLTTKGTAGTEPAAHNGLKITAAGQLNGLNLTSASLAMVNGANVTLNGTTAATTAPLPVIVGANGTANIVGIAHSQLLAASTAGGSSPAAIQTIPLNLNVTSSAVSNGLVTGSGPASLAIATAGAGGPLQLTSHNGGPIGGGSISSSSSSSSSSHSSSNTSSSSTGAANTTTVVGTIARSMYSAATIAPSMPTSTVAATTMVHVPTGGSKELINGTIGKNGTVRTDNSKLEIIASQSQPTNHSTQAVVGATALDPPGTKVITIMNGNTFALAPLDKDSKMGVVYSPILVPTSQGLRMIQQGSNGLATIELAPPNGGNRLQLHLTH
The following text describes a protein:
Function:
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix, basement membrane.
Domain:
The alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure; Domain VI is globular.
Sequence:
MTAFFLLWLALPGFLCAQQACSRGACYPPVGDLLIGRTQLLRASSTCGLTKPETYCTQYGQWQMKCCKCDSRLPRNYNSHRVENVASSSGPMRWWQSQNDVSPVSLQLDLDKRMQLQDIMMDFKGLTPAGMLIERSSDFGKTWRVYQYLATDCASTFPQVHQGQPKNWQDVRCRPLSQRPNGHLTGGKVQLNLMDLASAIPASQSKKIQELGDITNLRVNFTKLAPVPQRGSYPPSAYFAVSQLRLQGSCFCHGHADRCAPNPGGSTTAVQVNNVCVCQHNTAGPNCDRCAPFYNNRPWRPAEGQDTHECQRCDCNGHSETCHFDPAVFAASQGTNGGVCDNCRDHTEGKNCERCQLHYFRNRRPSAPIHETCIPCECDPDGAVQGAPCDRLTGQCVCKEYVQGERCDLCKPGFTGLTFANPKGCHACDCSILGARKDMPCEEETGRCLCLPNVVGPKCDQCAPSHWKLASGLGCEPCACDPRNSLSSQCNQFTGQCPCREGFGGLTCSSAAIRQCPDQTYGHVATGCRACDCDFRGTEGPGCDKASGRCLCRPGFTGPRCDQCQRGHCDRYPVCVACHSCFQAYDTDLQEQARRLHSLRNATEGLWTGTGLEDHGLASRLLDAKSKIEQIRQILEGTSVTEQDVAQVANGILSIRRTLQGLPLDLPLEEEMESFSGDLGNLDRSFSRLLLMYRSKKEQFEKLSSEDPSGAFRMLTMAYEQSSRAAQQVSDSSSLLSQLRDSRREAEGLERQAGGGGTGGAQLMALRLEMASLPDLTPTINKLCGRSRQTACTPGDCPGELCPQDNGTACGSHCRGALPRAKGAFHMAGRVAEQLRNFNTQLQQTRQMIRAAEEAASRVQADAQRLETQVSTSRLLMEEDVQRTRLLIQQVRGFLTDPDTDAATIQQVSEAVLALWLPTDSATVLRKMKEIQAIAARLPNVDSVLSQTKQDIARARRLQAEAEQARSRAHAVEGQVDDVVGNLRQGTVALQEAQDTMQGTGRSLRLIQERVGEVQQVLVPAERLVKGMKEQMSGFWARMKELRRQAQEEQAQAMQARQLAEGASQQAMNAQEGFKRLKQKYTELKDRLGQSPVLGEQGNRILSIKMEAEELFGETMEMMDKMKDMESELLRGSQAIMLRSADLSGLEKRVEQIRSYINGRVLYYATCK
The following text describes a protein:
Function:
Involved in microtubules reorganization during spindle and phragmoplast development.
Subcellular Localization:
Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, phragmoplast. Note=Preferentially localizes to microtubules minus ends.
Sequence:
MVKALQGAAQNLPADVNQLIDQLERHCLAPDGSLVTKSVYSDLQLAREEMSRERLRYLEAMAIYCEAVAMVEEYQQAISVANHGGIRDVQGLYPQLGLKNSPQVYETLEHRLVVAEAAQKLRLPLISDGGEIHEEEIEKWSILSRSSLDSASTSFTISSTSNSVNYANSSANSVAGGISLSAVDTDVVGGVPNRFLGITPAYLSYVQLQNTISMDMADYQMFLAREIEGRLKEKCDKLADAIVDDTDSSTGNRNSSARLPERVKFIIEEIERDEAALREDLYSADRKFAEYYNVLEQILGVLIKLVKDLKLEHQHKYNEMQKTWLCKRCETMNAKLRVLENVLLLETYTPDSISALHNIRNYLVEATEEASAAYNKAVTRLREYQGVDPHFDTIARQYHDIVKKLENMQWTIHQVEMDLKSHD
The following text describes a protein:
Function:
Regulates global gene expression after oxidative stress. Interacts and stabilizes mRNAs and may regulate their transition between different cytoplasmic components after oxidative stress.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAHQQQQQVQPAIEQQQLKQNNNSNTTNDNDHHHLSIKREKSMTTLRKKQSQRFTVAHTSNPGSSEPVPPLPNALNPPTHELRPPSISSTSDSDFSPLTQTHSQSNYMPNPHASSFDPASIFGNQFSTGPPPISRTGTNLSSVGSAAPSAIGSMNMNTTSTNQSGPAPEGDDDIIPTAIVIKNIPFSVRREQLLAIIEDLMIPLPYAFNYHFDNGVFRGLAFANFRSASEADAAVAGLNGFDISGRKLRVEYKKVLQAGEKERIEKEKAIKRMRSMQLQKESTLLDQYSVHSQPAMPSSSTHISFGNYTSHEDEYRGLGGMHNHPPMPSSIPHRPSQSVLNSNSNQHPFLSSNHELSSAQQAFENFSLSGALESKQSKELDMNDPQTLELYSRVVVFKEDKLRDELAFAKSLSGPQRRIVHQIAKKLGLVHRSEGVGEERFVVVSKLASGGAPRISRVASSANMGRAASGQQGAMGAGQGRYDGGLGTNSSALRMKKSMPDMRVREMSSGVFYPEPSPRDLLGRKSNINLRENLGSKQSPFSFQQPDEIPSVSIIPNHHHHHHHQQQQQQQQQLSSSSLSNNNPHQIIRQPKGPEGGAGKGFATSQLPSLRSPLHHQSSRTDLTSVFGTDDPCRPSENL
The following text describes a protein:
Function:
Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
Subcellular Localization:
Preautophagosomal structure membrane; Multi-pass membrane protein.
Sequence:
MMSTWQKAPNVFNFFKWQRTEPSSSLTTGLLDNASHEIELSNYGGVIPSPGSESPSGLLNGESLTVQPITDLDLFFERLYSYYRYKGLWCIIVKWAVELLSLGFIICFSGFFLLYVDWRGLKDAKCGMDAVESWTKPCDLVKEAIHEHPLSPFTLTTAIIVGYLALFFIYWLFCFLRFFAQLKDTLDFSHFYYNSLHVTDNEILTMPWETVLENFVQLQSSQRLCWTLNWFILQSMFDCNFRVRRDFVSNPTMLKKQLFAVGVAMLMLSSYLVIFMLVYLFLRHAEQFYNHPSTASSRRWSNLSRWLFREFNEVDHLFKYRINNSAEHASEYLNQISSGGSYMRSQFIMNLLWYAAVFGTITAISRAAVSDEILVLDPVKTMTFVVQHTHYMPKRWRGKENKDDVRLELKTLFQYTGMMLLEEMASIFITPFLLMFVVPKRVDDILQFIRNFTVDIEGVGNVYSFNAFDSRTMGILNMGKMEKSFLSFQSSFPTWESNSLEKQFLSNLRTFRDQKLPEINTRHSSSPTRPPHETSTSSTTLG
The following text describes a protein:
Function:
Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MSISSSSSSSSSSSSCLLLISLMLLAASCQGRPDLQHRNHKSQLAGLFGAEVAALLEDAGAADGSSGEEAALSQRAPPSIRALHPRSGRLGLRDDLEAEPPAENKPRRRLLKDFMSSRKMFRGRTKKMQQGRGCFGMKLDRIGSMSGLGC
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MERRKKQNEGLLSVYPPPPWYSRYFTDENVAKVKDLQSSDNSQLLEAPLKYLTPPSPPEAGAYHNFGDVWQVNDKLATLEDLGITQVYDGAAIRGEGQESGARVLELKKLTKSLLLAFVELTGIMGVSPEQFPAKFEHVRVLLINIHHILNEYRPHQARESLVTLMQQQINDKKQHVENIRQSCDKVRDTIRVLSKQFDQVDEFEETGGVTTEEVKYVSGKDKDLLVVKMAEQVL
The following text describes a protein:
Function:
Plays a role in pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MQSQKRGQQHKQGYQADLNKYFGKRLKIKLNAKRTIIGTVIGFDIFMNLVLDHCKELIPGQGAENKDNLYPGFSNVTDQLVDIGQAIVRGNSIIMWECLDKVKD
The following text describes a protein:
Function:
Has antibiotic activity against several equine uterine pathogens; S.zooepidemicus, E.coli and P.aeruginosa. Highly efficient against S.zoopedemicus. Not active against K.pneumoniae. Selectively inactivates microbial serine proteases (subtilisin A and proteinase K) without inhibiting mammalian serine proteases (human neutrophil elastase, human cathepsin G and bovine pancreatic trypsin).
Sequence:
EVERKHPLGGSRPGRCPTVPPGTFGHCACLCTGDASEPKGQKCCSN
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
Sequence:
MSKEETLYSVKVDQERVPLFDEDFYKGFRSELSVRFTMAALDPRAKSNDAVTVNVITRLEHPEEDGEESDEELFQEEKFTLCTLKKGSVYQQPIDIIFSPGEEVFFERVGGDIPVYLSGTCIITNIPEEEDSSDLENDFLYGADEFSSDEEEMDDISVTSSEEEEEENGARIEELNSDEEDAEQAEEEILEKPVPKDEVAEKHSKDKLKKEEKEKKTAVDVSDSVNGKKRKTEPAGEGEQTEKKSKSTKTYPKQVLEGNVTVQDKVKGDGPAAKRKKRVSMRYIGRLTNGKVFDKNITGKPFTFNLGLEEVIKGWDVGIVGMQVGGERTIHIPAAMAYGSKRLPGIPANSDLVFDVKLLAVN
The following text describes a protein:
Function:
Essential for the initiation of viral DNA replication, it may contribute to other functions such as controlling the switch to the late phase and leading to the inhibition of host protein synthesis. Required for late and very late gene expression (By similarity).
Subcellular Localization:
Host nucleus.
Sequence:
MNSILSRLFRDVTGDEEYAVNSLRDANRLIIIDTDTGTRRLLEHVSNFRRFLNTIRSDAAGACARHQRAARHDDEEEAPPAARVSFAGHSLVLENNDFCVFVKPFLLKRHYDEIKNYLKLDRFFKSDNPEHTNMCVQAGDYCYWPNWPASQAVSFTGWQLYLYVEFGIVVESTVPIIHNRRLGPVDLFVFNPRTFLNIEMNLSTNEAPPVKLFVNGKFDFEKKVAESGKAVESLFEIKMANGATATCKMIANLVNSNKNLFEVIRDNINLEECVTTPKYRHIIDVNLTKLRQFAHDGAVLAPPVERAFRAPTVTTILSASSENAEVIQSEIDAALVKVREGMVKVMAEFNRSDDPDLLQAYFKESGFKNFHFLLFNVWKQITKRDKKSFRETDMKLFFELVCETLFGNDSDALATALVKCEPFTTRGVATFNSLCDHWHCFKGVNPYTLLGSYYGAHYFIYLKLTSSDAHECDDPWAFNYKNAMECKVPPKALGEAFFIKVENVVTQVTLVFNGEHYQIVKKDDELYKLVETNPYKLQNIKFNNWKYMYHTKYGVYNVVTDDFYSNCPFLLGTTMPGTFKRPDDPPYLPEAVFAHMLATSAEERDILRTYHIAKLCRDVKMVKVNLGTVNLLGDCAPCKLDARLRLNDLFRELWNLDDDSLVTLALYVNKLRVEDIVHNFKCGACRASVQERKCRCVQKIKINRQALKTCLIFDLFVGDPELTQLMWMLIFATNKLYINTALIVTTSKLVAQHAHFFTKEHIKIAAILHRDLHKIEFVDTLMADVCNHDAFLAYLQHAVANEPAAAPAADNAVAKFYAHYANAANILHKYKNLWWDKIILARDSDTLSSWLTRFYLRVILSKMDVQNYPVAYLTQVVEGYLYFKRYTNFNHASSYMLMHFAASLSVPTDYGRKAVYLPGVPLSGKSTFFELLDFLVLMHKFDDDTHTGASKETSDKEVSNLNSEVYTINELKKCSESFFKKHADSSKSDSKSRKYQGLLKYEANYKMLIVNNNPLYVDDYDDGVQNRFLIVYTDHKFLPHVRFSGSVYHHILTKQYPQEPMVVDALKDSVRVFLAHVVRYQREPQTGLVPYKTLLDSDPVHQHNLTRLSVNNSPMYAVIYILNIKTAPRSANTFVTEEKMQEMIGYATLHLKSFLHPSFTQYNAAKNINAGTARSFVFDEKILLQQIKDKFKNNYDERGCKFNNLTMALNKLDININVPQFKC
The following text describes a protein:
Function:
Catalyzes the NAD(+)-dependent oxidation of the hydroxyl group at C3 of D-gulosides leading to 3-dehydro-D-gulosides. Probably functions in a metabolic pathway that transforms D-gulosides to D-glucosides. Is also able to catalyze the reverse reactions, i.e. the NADH-dependent reduction of the oxo group at C3 of 3-dehydro-D-gulosides leading to D-gulosides. In vitro, can oxidize D-gulose and methyl beta-D-guloside, and reduce methyl alpha-3-dehydro-D-guloside and methyl beta-3-dehydro-D-guloside. However, the actual specific physiological substrates for this metabolic pathway are unknown.
Sequence:
MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVDFRAASPFIDEDFNGEWQMFTPRPADAPRGIEFGKFQLGNMVVGDIIECGSDVTDYAVGDSVCGYGPLSETVIINAVNNYKLRKMPQGSSWKNAVCYDPAQFAMSGVRDANVRVGDFVVVVGLGAIGQIAIQLAKRAGASVVIGVDPIAHRCDIARRHGADFCLNPIGTDVGKEIKTLTGKQGADVIIETSGYADALQSALRGLAYGGTISYVAFAKPFAEGFNLGREAHFNNAKIVFSRACSEPNPDYPRWSRKRIEETCWELLMNGYLNCEDLIDPVVTFANSPESYMQYVDQHPEQSIKMGVTF
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MYKYMTRAGSKVACRFTRNMSTQAHKSSPGKFRKLVRLTAGGCLVGYTAAVFFASRDERFRDIFIEKFPFGRPIGEYFEEQEIKKNRDSPKPKPIPTSPSGQPNARTSHLSALYPDKSNPNAMTNNPDGDSHQERKFNLERALSSKGTKKEYFDPLTENQGNFFDPSSGVVAEEHKEYLPLILLHDSADHAARHSAMALNDLISSINTSIVTNDSVKNVSDSLIQLSEFVAVNHPEIQTQLSERLGEKARRFHALGEHYHTIIQDFLQNEVEHGPHQGHAAEVELTIYETDKMRDLRKNVIQEIHDTEDLLVKYCNRYSRPEGPVAEVITRRVPTVETVTLEPIDSTAKAAFDASKYKSQISAAEQSLAVLVAAVQHSSVLGVDPFVEGVKQAINNVDIGDRSKILTEALKNVTVPSDVNLTPYLEQITDKSS
The following text describes a protein:
Function:
Probable transporter.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MVDERTPLKAVTTREDAPTAVMRPKPVGKSIFALSILGTLSAASISLFSMYGQTLQHKLGFTQVQVNSVSISSLLGMYLLMPVIGYLGDTYGSNYLALFSWITFPASYSIASGIFSTAADWHRETGEALPRAAPEMALCFFFIGASTSCMYYASLKASAHSMSVYFAEDGKLQTYTPGYAIWGPVAAFGLSSLWQSQLLRAVFITGKNVNVAGIFLFFAGLYAVICGIIFFSCRTAESMASELRKKAEASTDCNCDGPGHEGATLKEFFTDKTAWLFLLCFVFIGGPFEMFQNNMGAILDTVTVENADSPSFSTHVSLFATFSTVSRLVVGFSSEAMESHVSRPVLLSVIALVAACIHLMVPSGIFTVFDNAKYFSVVTIVNGFSYGSSFTLVPTIVTKVWGIANLGTIWGSFILALAVGSLGYGLLFAKVYDAASEVGVGSMSQVCSGVHCYGLTFVITGTGLAFAAAAVFFIWVFMWKKRGIHM
The following text describes a protein:
Function:
Specific chaperone for cognate PE/PPE proteins. Plays an important role in preventing aggregation of PE/PPE dimers.
Subcellular Localization:
Cytoplasm.
Sequence:
MDQQSTRTDITVNVDGFWMLQALLDIRHVAPELRCRPYVSTDSNDWLNEHPGMAVMREQGIVVNDAVNEQVAARMKVLAAPDLEVVALLSRGKLLYGVIDDENQPPGSRDIPDNEFRVVLARRGQHWVSAVRVGNDITVDDVTVSDSASIAALVMDGLESIHHADPAAINAVNVPMEEMLEATKSWQESGFNVFSGGDLRRMGISAATVAALGQALSDPAAEVAVYARQYRDDAKGPSASVLSLKDGSGGRIALYQQARTAGSGEAWLAICPATPQLVQVGVKTVLDTLPYGEWKTHSRV
The following text describes a protein:
Function:
Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
Sequence:
MGSCINEEKLAKFFQRSLNALPAPYTSGLPNHLSLIFFVVSGLDLLNKTDILEKEKQDIINWVYSRQILPSKDNPEINLENCGFRGYNFLGQEFCCDKSVHTSENGPLEYDLPSTPNTYCALLILRILGDDFSGVNKKAIIDSLRKRQRESDGAISGSPNVGDYDLRHLFSACAISFILDDWSAINKESAIDYIKSCLSYEFAFGQTPQQEAHGGPTYCAIASLSLLGRLDVLEPFKEQLTFWLVKKQITGFCGRTNKDPDTCYAFWIGASLMMIDRYDLIDFASINAFIGSAQHEAIGGVAKEPGQLPDVMHSYLSLVGLSFGNIPSIQQVIPCLNLSKRAAGKDWFEKLI
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III (Pol III) which synthesizes small non-coding RNAs including 5S rRNA, snRNAs, tRNAs and miRNAs from at least 500 distinct genomic loci. With CRCP/RPC9 forms a mobile stalk that protrudes from Pol III core and functions primarily in transcription initiation. Pol III plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-kappa-B through the RIG-I pathway.
Subcellular Localization:
Nucleus.
Sequence:
MFTLVEMTDTVRIPPHIFHIKLNDAVIEELNNKFANKVVYNVGLCIALFDITKLEDSFIFPGDGASHTRVHFRYVVFRPFMDEILQGRIRSCSREGVHVSLGFFDDILIPPDALQQPSKFDESEQVWVWEYETEEGTHDLFMDINEEIRFRVVDEVFVDTTPTGPKVSEAAESDKEAKKSPYALVGTISEPGLGLLSWWSSVG