lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Multicopper oxidase that catalyzes the oxidation of a variety of substrates, including phenolic and non-phenolic compounds. Substrates include syringaldazine (SGZ), 2,6-dimethoxyphenol (2,6-DMP) and the non-phenolic compound 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS). Has no tyrosinase activity. Is implicated in the biosynthesis of a brownish pigment that characterizes sporulating colonies of B.subtilis, and which appears to be a melanin-like product and to confer protection against UV light; In vitro, also shows strong bilirubin oxidase (BOD) activity, and can catalyze the oxidation of free bilirubin (UB), direct bilirubin (conjugated with glucuronic acid, DB) and ditaurobilirubin.
Subcellular Localization:
Spore coat. Note=Localized to the surface layers of the endospore.
Domain:
Glu-498, located within the entrance channel of the trinuclear center, plays a key role in the protonation events that occur at the trinuclear center and in its stabilization, controlling therefore the binding of dioxygen and its further reduction. Asp-116, situated in the exit channel of the trinuclear center, and its hydrogen bond connectivity are highly relevant for the overall reactivity of the laccase but do not appear to play a critical structural role.
Sequence:
MTLEKFVDALPIPDTLKPVQQSKEKTYYEVTMEECTHQLHRDLPPTRLWGYNGLFPGPTIEVKRNENVYVKWMNNLPSTHFLPIDHTIHHSDSQHEEPEVKTVVHLHGGVTPDDSDGYPEAWFSKDFEQTGPYFKREVYHYPNQQRGAILWYHDHAMALTRLNVYAGLVGAYIIHDPKEKRLKLPSDEYDVPLLITDRTINEDGSLFYPSAPENPSPSLPNPSIVPAFCGETILVNGKVWPYLEVEPRKYRFRVINASNTRTYNLSLDNGGDFIQIGSDGGLLPRSVKLNSFSLAPAERYDIIIDFTAYEGESIILANSAGCGGDVNPETDANIMQFRVTKPLAQKDESRKPKYLASYPSVQHERIQNIRTLKLAGTQDEYGRPVLLLNNKRWHDPVTETPKVGTTEIWSIINPTRGTHPIHLHLVSFRVLDRRPFDIARYQESGELSYTGPAVPPPPSEKGWKDTIQAHAGEVLRIAATFGPYSGRYVWHCHILEHEDYDMMRPMDITDPHK
The following text describes a protein:
Function:
Deubiquitinating enzyme that specifically hydrolyzes 'Lys-63'-linked polyubiquitin to monoubiquitin. Required for the stability and translation of a subset mRNAs with a high abundance of rare codons by mediating deubiquitination of 40S ribosomal protein RPS10/eS10, thereby antagonizing ZNF598-mediated 40S ubiquitination. The abundance of rare codons in mRNAs can limit the translation rate and can lead to ribosome collisions that trigger activation of ribosome quality control (RQC) pathway by ZNF598. OTUD1-mediated deubiquitination prevents activation of the RQC and subsequent dissociation of ribosomes and stimulates formation of polysomes and translation.
Sequence:
MTAPTSPPTGGRSNYRFSLRSSTKSSNKRGPHKGVRFWFSSSPKGAADGGDLAADAVAAAREVDTEVAETKPRAESGSGYVPRVEYGSPRTDVEERDAPWTSDEEVEAHYAALDWAVISIAKDGNCLFRAISDQLYTNELFHQDIRRRLVDFIEREQQLFRPFVEDEELSDYCTRMRRDGEWGGHLELYAAARLFNIHIVVHTGPVRRLRVTNDDEGDTEKQSPPPPPPYRILQLLYKDDHYSSLHSNEPVQMIEPATTTAATIDDTTDKRARSPTKAHDSPDKKCVNVQKSPSKCVSIKNLPKRSYKAQDPNGKTVKFKEAVEAKPPPREEGKTFLYQEEELPECGVYLPKQVLFKRGKRRVSGATLFSLVHVPSSSNLSPVVESLSTSESSTSSKCSSSTECSSSSEEHENQSETKAPLPTRPKPKAPTLRAVPVEFPSKTIFHKGRAAAAVC
The following text describes a protein:
Function:
Required for photosystem II assembly/stability and photoautotrophic growth under low light conditions.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side.
Sequence:
MAQAMASMAGLRGSSQAVLDGSFQLSGQTRFNIPSNNRVAVGRSGFTVRAHQTPAEPETGRRAMLGLVAAGLATGSFVQAVLADARSIKVGPPPPSSGGLPGTLNSDEPRDLVLPYKDRFFLQPLTPAQAAQRAKESAKDILGVKNLIDKKAWPYVMNDLRLKAEYLRYDLNTVIAAKPKDEKKTLKDLTKKLFSTIDDLDHAAKIKSTPEAEKSYAQTVSSLNDVLAKLG
The following text describes a protein:
Function:
Involved in regulation of actin cytoskeleton organization and endocytosis.
Miscellaneous:
MISCELLANEOUS: Present with 1551 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm, cytoskeleton, actin patch. Note=Cortical actin patches.
Sequence:
MNQPQIGTYNVGTQLTVGSHQVEIIKYLTSGGFAQVYSALINPPDPHSNSSVACLKRVIVPDKPSLNTLRAEVDAMRLLKNNRYVVSYIDSHAAKAMLHNGSYEVFVLMEYCERGGLIDFMNTRLQNRLHEFEILQIMSQVTQGVAAMHALQPPLIHRDIKIENVLISANNEYKLCDFGSVCGIIRPPRNSQELSYVQQDILKNTTAQYRSPEMIDTFRGLPIDEKSDIWALGIFLYKLCYYTTPFEKGGDLAILSGKFEFPLYPNYSEQLKGLIRDILVQDPRHRPNVYQLLKRISIMQNVPCPINDIQVVQAPSSHLNLTELHQLSATQNILSLNSPTTMENTMPNATFQISMADNTTTAQMHPNRKPSQIAYDASFSNSAKGSQPLFDKSQNMYHALDPPLVEPLASSVSNNDNELKANSATKLKQAIVSEAHTFRQNNSIDFPLQNIIPQYEDSSSSSDESYSGDVDELKKTRSLGSYSTRGNIKKNQSVKESLTSSSLPGTSFTPTSTKVNLKHENSPFKSTFVNTIDNSKDDLNKPSYEDLDVSKQNLKNSIQQRMIDKLNSSEESFNARKMSKVKLHEKGEIDKPTMLKSSGPISKDKKTKPTPPPKPSHLKPKPPPKPLLLAGRKLSLDK
The following text describes a protein:
Function:
The imp locus inhibits the extrachromosomal maintenance of the streptomyces plasmid SLP1. May function as a transcriptional activator.
Sequence:
MISAHVWADAQRLWDFQQMGHEPHPCSVAIGLGSHDLGVAETTAELYHRGMAPVIVFTGATSRTTHERMPRGEAEHYRERAVELGVPERAILVEPNARNTGENIRLSRALLEDLGMPVTSVLLVSKPYEERRAYATARKLWPNVEWVCVSTSMTLPDYVKSIGDARLVIDMLVGAQQRLMVYPRQGFMIKQEIPEPIMTAYEHLRGHGFTSRLVPETAEQT
The following text describes a protein:
Function:
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Sequence:
MRRLTREGRACGCERANHSPPAAGSPRGSLSRARFPKMADAKDGCGLGEVAAGNGRRLHLGIPEAVFVEDVDSFMKQPGNETADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQTLEILKYMQKKKESTSSLETRFLLADNLYCKASVPPTDKVCLWLGANVMLEYDIDEAQALLEKNLSTATKNLDSLEEDLDFLRDQFTTTEVNMARVYNWDVKRRNKDDSTKNKA
The following text describes a protein:
Function:
Mitochondrial ribosome (mitoribosome) assembly factor. Binds at the interface of the head and body domains of the mitochondrial small ribosomal subunit (mt-SSU), occluding the mRNA channel and preventing compaction of the head domain towards the body. Probable inactive methyltransferase: retains the characteristic folding and ability to bind S-adenosyl-L-methionine, but it probably lost its methyltransferase activity.
Subcellular Localization:
Mitochondrion.
Sequence:
MLTARKVPRACQSCRSQLLSLFEHGFTRPTASTASSHSRYRDLRHRSIQPRTNALRLFSTTLTRSDESPTSKSPTESEKEAAAAAAAEIESVVRQARQTFGETLPKDYLSVQEYQLYERLYGPPLRETRPEDLEYLQVEEEDIGEDGPSRNILLRENADGEFEEVEFDPELGFKVVEDGSDGFASASEGEELEFEEESEPDMELEAEEFIDAETPAGPDTTNLTFQGQNQREVDAIARLQRDMDEAMARAAEQEDTVFDEDYEEEESSEESEEELFEDEEIFDEEDHDSYTSSDEIRTHPHTRTSRFGTSPRKLKLLPQKHVGLDASQHRMSEIEADAYLAGVMSGTYTSVMSTLVEVRKRLGPEWIREMLFREGGQGPRILDAGAGGAGVIAWKEILRAEWDVLKDDGIVEGDEPPSGKHTVLTGADSLRHRISRLLDNTTFLPRLPDYVHSSSGEAQLDGGPAQPRKVYDLIIAPHTLFPLKEDYRRKHMVQNLWSMLDPKGGVLILIEKGLPRGFEAIAGARSLLLDSHISSPGEEVVEKELQSLSDTEARFVEKEEGMIIAPCTNHTKCPMYPVPGLTPGRKDFCHFEQRYLRPPYLQKILGASSRNHEDVRYSYLAVRRGIDGRKEEAILQGDAATDQSFAGYEEHDLSDSPDIPAEGDVPFHPLSLPRSMLPPLKRRGHVTLDVCTPSGKLERWTVPKSFSKVAYRDARKSKWGDLWALGAKTRVLREPRLGRGGAGAVNSKGSKPGKVLSKSAAKKKKNKFNIIMGRDGMEGLEESRDSKRIFKPEKRTKGGRFVKPKKPITEDDI
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It probably triggers the ubiquitin-mediated degradation of different substrates.
Sequence:
MGLLPLAGSGALGINKTRLKGQEAGMCPAKHAACAPCAANLASKCPACDGAYERDEGADRYLMAVRVPCPNQAYGCGSSMVYCMAGDHRLVCPHAPCRCPEPGCGFLGSPPALRGHLAERHQWQVTDIAYGSVLEVQMQPAELVRRLLPAEGGERLFLLVASERGVKVVRVSAAADEEGPAASWYRCKVWVHASVDTDTGHMDVLMLDAKVGSCAVPSVEAAMGAGGRCLPVPSDVPAPEGGGIVIRRRIDKEVKASRSPRTRG
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MKRTAVIFIEKATPSTITQFHDILSTHVLAIQEKWSFELKTFRSSIKNLPPSDTKVLYSLQLTHRDNQTVVIKNQSAIVTGQHSTDALTSNGCSSGFPEPFDNILTSKLSNIWTQRQSTKGNFGTTYKTSELIIRASNVFSSSGFKGLLLEIECTDPVSAEEFDRRVANIRAMLSEIDINDYKLNKDEMNEGKPVFLCDLAYQYVKVLD
The following text describes a protein:
Function:
May play an anti-apoptotic role.
Sequence:
MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERRRAGGGAERSRGRERRGRGTSPRGGGPLILLDLNDENSNQSFHSEGSLQKGAEPSPGGTPQPSRPGSPTGPPEVITEDTQPPQLGQERDPGGTPAGGTDEPPKLTKEEPVPELLEAEAPEAYPVFEPVPSVPEAAQGDTEDSEGAPPLKRICPNAPDP
The following text describes a protein:
Function:
Component of the histone acetyltransferase (HAT) complex ATAC; predominantly involved in acetylation of histone H4, including at Lys-6 (H4K5ac) and Lys-13 (H4K12ac). May be part of several different complexes, including Gcn5-independent complexes involved in RNA polymerase II-dependent transcription.
Miscellaneous:
MISCELLANEOUS: This protein is produced by a bicistronic gene which also produces the Polr2D/Rpb4 protein by alternative splicing.
Subcellular Localization:
Nucleus. Chromosome. Note=Predominantly localizes to decondensed chromosome puffs enriched in phosphorylated RNA polymerase II, but also colocalizes with Ada3 and Gcn5 in some euchromatic regions flanking chromosome puffs.
Sequence:
MSFMNPVDMVDEDAADLQFPKVALLHIFTTLNCLFAVEPLGPQVKRFIHAHQNEHTRNSMVLYNPHTLHRYLEEMEEKTRDQNSSVPSATKDANRCATCRCSLTEPYIKCSECLDTLLCLQCFSRGKEAFSHRNNHAYIIVRDNIQVFADEPHWTARDERILLKTLRTHGYGNWEAVSQALDQRHEPAEVRRHYHDCYFGGIFERLLNLKHARDSYVPERMPYVFKMRSLDPPRHDDIASMQFRLSAGYRCARGDFDTPYDTSAESLLSIMVDHRGRDDDNEASESEFEREVTEELQLGLVRAYNNRLRERQRRYKIMRQHGLIMPNRTVSWISKYVHAFGSDASCMRFLGFMQICPDPIKFDMLLESLRYYRELHSQLHKLYDLREHGVRTLSGAKLYARLSKERQQAQRDYSRLKQTDAFDWQQLVQHYESNRSGDPGPLAINSKLYVMNTRRKASPIEIGGGKHFTHCLTPTEYNFSLIPDLPGYSKLDDGERKLCSVARLVPQSYLDYKNQLVTEQAKLGYLRLADARRLIKIDVNKTRQIYDFLLEHGHISRPPSYG
The following text describes a protein:
Function:
Component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. Required for efficient export of polyadenylated RNA. Plays a key structural role in the oligomerization of the THO-DDX39B complex. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NXF1 pathway.
Subcellular Localization:
Nucleus.
Sequence:
MASDDDVIRKRLLIDGDGGGDERRLNALMKLFIKWCNSPDPDISTHQRMLSFLAVGEFAVAKSSFVYEMNMKQMEKYKQLQEEIDANVSLAKKEIEKCKTELAEARLIRKNRKEYDALAGVVLQHPDRQQTEGQISELKCDLKELEANELRLVEKLDLRKKQFHALLTSINHLQIMLNETEEEEEDKRSLDVDMDDAKMDTTPEELAQKT
The following text describes a protein:
Function:
Transcription factor that may function in dorsoventral specification of the forebrain. Required for axon guidance and major tract formation in the developing forebrain. May contribute to the differentiation of the neuroretina, pigmented epithelium and optic stalk.
Subcellular Localization:
Nucleus.
Sequence:
MFGKPDKMDVRCHSDAEAARVSKNAHKESRESKGSEGNLPAAFLKEPQGAFSASGAAEDCNKSKSNSAADPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGESKELGRTPELANIVPQPMSGPGGKRLVLRPQHRTPALDPAAAVVDYSHEYLKEESCTQTPAAEEAGRFHQTKKGGLCFLSPEKPGLLEGPGPPFADLAGEPVRTHLSGWTELAVCSPLGTLQSQPLPTPGDNEANTMVGNGGHKFDLISNKTSNNYVKPNEVELVFNCL
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. Involved in the regulation of mitotic metaphase/anaphase transition.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton, spindle.
Sequence:
MASSAREHLLFVRRRNPQMRYTLSPENLQSLAAQSSMPENMTLQRANSDTDLVTSESRSSLTASMYEYTLGQAQNLIIFWDIKEEVDPSDWIGLYHIDENSPANFWDSKNRGVTGTQKGQIVWRIEPGPYFMEPEIKICFKYYHGISGALRATTPCITVKNPAVMMGAEGMEGGASGNLHSRKLVSFTLSDLRAVGLKKGMFFNPDPYLKMSIQPGKKSSFPTCAHHGQERRSTIISNTTNPIWHREKYSFFALLTDVLEIEIKDKFAKSRPIIKRFLGKLTIPVQRLLERQAIGDQMLSYNLGRRLPADHVSGYLQFKVEVTSSVHEDASPEAVGTILGVNSVNGDLGSPSDDEDMPGSHHDSQVCSNGPVSEDSAADGTPKHSFRTSSTLEIDTEELTSTSSRTSPPRGRQDSLNDYLDAIEHNGHSRPGTATCSERSMGASPKLRSSFPTDTRLNAMLHIDSDEEDHEFQQDLGYPSSLEEEGGLIMFSRASRADDGSLTSQTKLEDNPVENEEASTHEAASFEDKPENLPELAESSLPAGPAPEEGEGGPEPQPSADQGSAELCGSQEVDQPTSGADTGTSDASGGSRRAVSETESLDQGSEPSQVSSETEPSDPARTESVSEASTRPEGESDLECADSSCNESVTTQLSSVDTRCSSLESARFPETPAFSSQEEEDGACAAEPTSSGPAEGSQESVCTAGSLPVVQVPSGEDEGPGAESATVPDQEELGEVWQRRGSLEGAAAAAESPPQEEGSAGEAQGTCEGATAQEEGATGGSQANGHQPLRSLPSVRQDVSRYQRVDEALPPNWEARIDSHGRIFYVDHVNRTTTWQRPTAPPAPQVLQRSNSIQQMEQLNRRYQSIRRTMTNERPEENTNAIDGAGEEADFHQASADFRRENILPHSTSRSRITLLLQSPPVKFLISPEFFTVLHSNPSAYRMFTNNTCLKHMITKVRRDTHHFERYQHNRDLVGFLNMFANKQLELPRGWEMKHDHQGKAFFVDHNSRTTTFIDPRLPLQSSRPTSALVHRQHLTRQRSHSAGEVGEDSRHAGPPVLPRPSSTFNTVSRPQYQDMVPVAYNDKIVAFLRQPNIFEILQERQPDLTRNHSLREKIQFIRTEGTPGLVRLSSDADLVMLLSLFEEEIMSYVPPHALLHPSYCQSPRGSPVSSPQNSPGTQRANARAPAPYKRDFEAKLRNFYRKLETKGYGQGPGKLKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHDILDLTFTVNEEVFGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSVFDARELELVIAGTAEIDLSDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSSIPYEGFASLRGSNGPRRFCVEKWGKITALPRAHTCFNRLDLPPYPSFSMLYEKLLTAVEETSTFGLE
The following text describes a protein:
Function:
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MVTTWFVLLFFYLFFKLGTRNLQLIPGKFQSVLEGIYEFLDGTIGQILGVWKKKYYTFFASLFLFIFLSNIITFFPIPWFSIKNGIFTIYPAFRAPTADLNTTIGLALIVTTLFISINIKNNGVSGYLKGFADPTPVMLPLNVVGEFAKPLNISMRLFGNMFAGMVIMGLIYMAVPYFVPAALHLYFDLFAGLVQSFVFVTLSMVYVQGSIGDTEYTN
The following text describes a protein:
Function:
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2 (casein kinase II).
Subcellular Localization:
Nucleus. Chromosome. Note=Colocalizes with RNA polymerase II on chromatin. Recruited to actively transcribed loci.
Domain:
The C-terminal Glu-rich acidic region is essential for FACT activity.
Sequence:
MAVTLDKDAYYRRVKRLYSNWRKGEDEYASIDAIVVSVGVDEEIVYAKSTALQTWLFGYELTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLVREKNESNKSSFDKMIDAIKESKSGKKIGVFSKDKFPGEFMKSWSDCLNKEGFDKVDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVEMCYPPIIQSGGNYNLKFSVVSDKNHMHFGAITCAMGIRFKSYCSNLVRTLMVDPTQEVQENYNFLLQLQEELLKELRHGVKICDVYNSVMDVVKKQKPELLNKITKNLGFGMGIEFREGSLVINSKNQYKLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTVLVDEDGPATILTSVKKKVKNVGIFLKNEDDEEEEEEKDEAEDLLGRGSRAALLTERTRNEMTAEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNPSLMPKEPHIREMKIYIDKKYETVIMPVFGIATPFHIATIKNISMSVEGDYTYLRINFYCPGSALGRNEGNIFPNPEATFVKEITYRASNMKAPGEQTVPALNLQNAFRIIKEVQKRYKTREAEEKEKEGIVKQDSLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVNGFRFTSVRGDKVDILYNNIKHALFQPCDGEMIIVLHFHLKNAVMFGKKRHTDVQFYTEVGEITTDLGKHQHMHDRDDLYAEQMEREMRHKLKTAFKNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTCLLQPTSSALVNATEWPPFVVTLDEVELIHFERVQFHLKNFDMVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTIVDDPEGFFEQGGWSFLEPEGEGSDAEDGDSESEIEDETFNPSEDDYEEEEEDSDEDYSSEAEESDYSKESLGSEEESGKDWDELEEEARKADRESRYEEEEEQSRSMSRKRKASVHSSGRGSNRGSRHSSAPPKKKRK
The following text describes a protein:
Function:
Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity. Involved in mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MATNNGDVLMLEATPEAARPWASAANAEVIDALPYIDDDYGNPLIKSEVDRLVEEEMRRSSKKPADFLKDLPPLPKFDFKNCPVLGKEYERVRAGKPPVRIDFESRYKLEMPPANKRNDDAAWKQYLQKNQRSLQQKLIELENLELMSKLGPELWRQNNHRLEVFLTRMQRLAQEQNEEIEKVNRERKYHQQTTSYELNALSQEWRQLCVKNMEIQSACAMLETQIDSFKKEAAERGWNLEEKLENVEPLQMQ
The following text describes a protein:
Function:
Repressor of the galactose operon. Binds galactose as an inducer.
Sequence:
MSTIRDVAKLANVSVATVSRVLNHSLSVSENTRLVVEQAIAQLAYQPNANAQALAVQNTDTIGVVVTDVTDAFFAILVKAVDKVAEAHQKTILIGIGYHHAEKEREAINTLLRKRCSSLVVHSKALSDDELSHYLNTVQGMVIINRVIKGYEHRCVSLDNQKGTYLATEMLIRYGHQHIAYIGSNHAIFDEVERRNGYLAALKDHNYPIIEQAITLNSPDFEGGEKAMIDLLSYNKNLTAVVAYNDSMAAGAISVLNENNISVPSQFSIIGFDDMPIARYLIPKLTTIRYPIDLMATYAAKLALSLTDEKIITPPVVQFNPTLVRRFSVESR
The following text describes a protein:
Function:
Involved in transport of proteins into the mitochondrion.
Subcellular Localization:
Mitochondrion outer membrane.
Sequence:
MAAAATAAAEWQDAERKVLVARKPGFGLPTACPTCLPVLLYLRMSQVPFGIHVDTSFPDADHIPSVEFGDCVAFHNEKGGVIEYLKDENILDLTSKHPSVSYPDVLSTKAMVTTWLADALQYELWVVTDGSIAQDIYFRELSWPIGKILHWKKIRDVKQQLGITKINAAEKEEEIYRKASDAYDALSTRLGDQVYLFGDSPTDVDALFLGHVLFVLNALPETSSLRSHLQKHDNLINFAEHHKVQLLEVDSSLAGSGSSDPSSSSTPRKRASSGRSYKPKPRAKKERTEEEKKFRRRTKYFLATQLVAVLVFLSIMGGVDSSEVDNEYDVDYED
The following text describes a protein:
Function:
ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and for completion of the abscission stage of cytokinesis. Also plays a role in axon growth and the formation of axonal branches.
Subcellular Localization:
Cell projection, axon. Membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Nucleus. Note=Forms an intramembrane hairpin-like structure in the membrane.
Sequence:
MNSPGGRSDKKKPVTRAAETGPGPPTPPPPAETQVLLAPPSLHTRNLHLFSYPLLAAFSLLRFLAFQLGLLFVWCCERLSCRVMAEKRSAAAQDRPQEPEVVRNYHQQAFHYISMALRVDEEEKDQKEQAIRWYKKGIEELEKGIAVSITGKGEQYDRARRLQAKMSTNLIMAKDRLQLLAKLQADIQGQHSHMEVCSDNTNLPCRNGLLKPEKGAVPKKKDPPPLTSNSYSRVKAPPKSGSLGNRISNCTGVSSSARQAGAHIPSNRGVAGKNNTRTNKPTTPTTAVRKKDMKNLRNVDSNLANLILNEIVDSGPSVKFADIAGQDLAKQALQEIVILPSIRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFSVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSGGDDRVLVMGATNRPQELDDAVLRRFTKRVYVSLPNEETRLVLLRNLLSKQGNPLNEKELTQLSRLTEGYSGSDITALAKDAALGPIRELKPEQVKNMAASEMRNIKYSDFLGSLKKIKCSVSPSTLESYIRWNKEFGDTTV
The following text describes a protein:
Function:
Regulator of mitochondrial fusion required to maintain neuronal homeostasis.
Subcellular Localization:
Mitochondrion outer membrane; Single-pass membrane protein.
Sequence:
MQRVMPASWSSGGSLLPFRVSTTTKVVLFSLTAGVALMSVLSRFLRRRKPPRPPRRARKYTGRRNRNSMRSPNDLISIAGSKASARSGSPVGSTLAYSDRLSMASGSIGVGVLGVQNAGPGSSVVTQLTAQQLGMMGMEALDTVINFWEDALAAHYSPGGLPALLTTAEDSEFCREIQNLLEMAYTLQEQSELLFLDQRSVLFREEHSIDEAEEEAGEADDDRRSRKSGSVLSRAGSDPNFDSAESFASALDQVADLREFDGFIETSYEEYPLFQSALKHHDEYTVPCRTIRAELMHCSTDTEYLAKLHCVRLAFQFLFKDPAVGQWICDAGRQILTDLLCLGDKDTKEFLVGYEDMVNYLHDSNNWPCIQMELEQRNVKAMTFYDICLDFIILDSFKDLDAPPASVTAVVQNRWLSNGFKETALTTAVWSVLKAKKRMLKFPNGFMSHFYVISEQISPLMAWGFFGPNENLRDICHYFREELLAFLGDIFSFQKSRFTTIEEFSQDVLQHMQTRVNNIGVKFSQ
The following text describes a protein:
Function:
Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built; The GINS complex plays an essential role in the initiation of DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MSLYLDLYSFENFNENYFKIDDILATQERLVCRFETEIPNMGYLDTSSDSTNILPGTKLELPLWLVLPLSTRQRQYATVDLPKQYGSAYREIFSADASVVDLHKLGPHYYRLGLQLVNCCYLEAVDICKSLLTTFQKRLCRIIDTSLNSSEQDANKFKEILDQVERCLYRCGQKCTQEFLKWQSREIEKITSSDMVVNIRKRKRYQMENS
The following text describes a protein:
Function:
Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for an ER lumenal chaperone of HSP70 family (By similarity).
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MSGKQVVILLGSVLILGCLQVAAATETDNKTNDFVATDEWQTIAEGQAIPRGLHVRINLQTGLKEAKLLDESERGTSLQSQPDDQNARESHDDNEPLALDYKPDIIEESIRRVKEQKKSYAELRKAYKEFQKNFRTDGELIVQLIDQFRNFSRTPLESEMRSKLDCLENLEYLLHQIDNALMFIDNGGLDDVLLPIVVNDTSTSLRVSAMRVLGSLASNNPKAQIKVFEKNFGSHLAQILTSSGNVGEISAALHAFGALLRKFPLAQQRVLSTSGTQALIKVLQSPDVELRSKAKVVTLISDLVLEKRSVLDVSKDDPEASSTMAQYVLLDFESWLKTPGYCAAVDTVLTKEFLLLLEQPEVVEQFATALETTEDMCTSTWSQSSGLRHALLTVRNRYANSTDEYRLEVSQILAKLCERLFNKPKHTEL
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
METLFRCRYCHKACNNSLQLEKHERTHQEETVVTCRGCGEHFESKDLLARHPCTGSDKGNFCAKTHATDTELQEHEQGHLRGVEKFQCKLCNCNFDMVHDLQRHLEMHNHTNKYIYMCPKCSKRFESKLSLECHLQEHEEVKSGSQDPLRVIPSNDAVDITGSTRLETFFCNVCGQTFNREGQFRQHLDGHFQRNLYECDICNSRFAGPFLLQHHMEVHSSARPFVCSQCGTGYRQKELLMKHFKIHGVPKMDNRDQLQEASSKQEVKQTGVFISHEESDASALIDKKVNQHLDSDGANFFDLLQTCNSEDSESIFWASQAGKDDFTKINPVYEDLLSQTALQNEQLHPKQLRENSLPMSGEGGDQSPPLVKMKGKRRKSFPCDICNKVFKFKSHCQRHRRIHTGEMPFKCGVCGRKFRWRSSLVTHACLKYRGKDKPSTSDISLVHSAEHLNDHQQGHSGECVPEVNGHGEVTQNANDGFVCSLCGGNCATEILLQSHTCVLDGRKSDPPTSEIQMQWQSDRVDPAKRSVVVSSTMPTENSQSILPMTGAGTNQTSDPAVGVVQQKQLQGSRKWGISWKTRQPRVSTPSANTAVTSHPSAVKERNKVFACEFCYKVFLCKNKYLRHKRLHTGEKPFECVKCNRRFMWASSLASHKKTHEKRDLHVYATNHDVISVIDSEQSDEATLEQSGWIPEVKEERGLDKAFICGQCGKSFTSEHKLRCHASVHEVHKYFSRSAPRTDTGLAQVSYRAKDVTQKSNVEPKHKEKCHTRKPEGTTSETGVLSRKRNRRQFVCEYCNKVFNHRSRYVRHLPIHTGEMAYQCSLCHMKFKWRSSLDSHKKSHDKKKGGTSSDDSLPFIDAEKSGELMQEQPDGTLEENEGTVGDEMFICLVCGMDFDTEMQLQSHNSTHEDTKYDPISVPRTDTDVAQLSGRAKEAPKQNNPENSKGNEKPHTGRIGNPLETDKFHKQKKIIKNFECEVCSKVFHIKNNYHRHKLLHTEEKPFQCDQCEKAFKWGSSLDSHIKSHNKKKGPTSSSDYVSLIANELTQEHSEPIPGCSQDEKSASTSLKPFVCPQCGMDYVSDLELQIHMYIHGDEAYLQRVQTKKRMDGTDPEKIDRPVMQTTQRPTANVPPHQVHEPESRGIRSTEKSGTSGSTTLERGTMQKQTSKNYVCEICGKSFGSSNHYRRHMPLHTGEVPYECERCNKKFKWRSSLDSHRRSHARKDALTDV