lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Peptidoglycan polymerase that is essential for cell wall elongation.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MFDKFFINRKLLKELDYSMIIISVAIMIFSALNIYSATHMKYGTSFFQKQLIWLAVGLIIIYVVLIFDYIIIENYANIFYWFTIFLLILNDTVLKKTVNGAGSWLKLGPISIQPSEFAKMALIIMLAKKLDDMEGEINNLRNFFTLAFYAVIPMILIVIQPDMGMTMVFFFTVLGMFFVAGLDGKVISGGLAGLTALVAIIWNSPLMQQYWKNRLTSFLHPEADELNTGLQLVQSKIGIGSGGFLGKGFLKGTQIAGGYIPEAHTDFIFSVIGEEWGFIGAAILLIFYGILIYKFIKTAKNSKDIFGTMVTIGVTASFMFSILQNIGMTIGIVPITGIALPFMSYGGSSSLNNFLALALVLNINMRRKKINF
The following text describes a protein:
Function:
Phosphatidic acid-binding protein involved in interorganelle phosphatidylserine (PtdSer) transport. Linkks a PtdSer donor membrane (via binding of SCS2 and phosphatidic acid present in the donor membrane) with an acceptor membrane (via its interaction with PDR17), forming a zone of apposition that facilitates PtdSer transfer.
Sequence:
MTTFRPLSSFEKKILTQSLNDQRNGTIFSSTYSKSLSRENDADWHSDEVTLGTNSSKDDSRLTLPLIATTLKRLIKSQPALFATVNEEWEFEPLKQLKTSDIVNVIEFETIKDKEVNCHWGVPPPYLLRHAFNKTRFVPGSNKPLWTLYVIDEALLVFHGHDVLFDIFSAANFHKLFLKELNEISTVTHSEDRILFDVNDINLSELKFPKSIYDSAKLHLPAMTPQIFHKQTQSFFKSIYYNTLKRPFGYLTNQTSLSSSVSATQLKKYNDILNAHTSLCGTTVFGIVNNQRFNYLKSIVNQEHICLRSFICGIAMICLKPLVKDFSGTIVFTIPINLRNHLGLGGSLGLFFKELRVECPLSLIDDELSANEFLTNSNDNEDNDDEFNERLMEYQFNKVTKHVSGFIMAKLRSWEKNGFNDDDIRRMKYDNDDDFHIQNSRTKLIQINDVSDISLSMNGDDKSFKIVSTGFTSSINRPTLMSLSYTYCEEMGLNICIHYPDSYNLESFVECFESFIE
The following text describes a protein:
Function:
Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAESSLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPLKKWWKVRVERVGIPMLTAIPLLTLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRIRNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGMFNFIVMQTLFYLPFFILGALAFIFPHLKALFTTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETESVITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHITSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR
The following text describes a protein:
Function:
Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
Sequence:
MIKTILLLLINFMLILIVNGDIWNYCDGNINPTFKINKLTLLPDPPLVGKEVTISLEGSLNEQITSGSSIFNVAFFINGGWRQLPTFHNDICKVLSCPVSAGPFTYSTSIKVPIFTPHGQYKGQLTLTDQSNRNVTCLTFQTYLK
The following text describes a protein:
Function:
CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
Sequence:
MDRPIVARNFAARADLELRYRTERRIGTGSFSTVILGEHRRSARRVAIKVMSRRNIIEGGMREKVAREVRTMALLRHPHIVRLYEVFETPRDVLIVMEYAERGDLYEYLLVQRNQRLEEAEARWFFQQLITGVEYCHSKSAIHRDIKVENLFLDSQRHIKIGDFGLCNTMQEGGFLRTSCGSTHYAAPELLLRRPYVGPEVDVWSCGVVLYVLLGGCYPFDDANTTTLYSKILSGTFNFPLFVPDGPRDLISRMLTVDPRARITVAEIKEHAWFRINIPPHLSMRSYYSTIDMDVLARVTQLGFERQLLIMDLLNNESSEAAVTYYIILNCDRQISAGFA
The following text describes a protein:
Function:
Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism.
Sequence:
MSTAAAQEPEVLVDMKGSVAVVTLNRPKALNSLSLGMVQQLLALNTQITAQPRPGEPVSCVVVKGAGGKAFCAGGDVKELVVRALARNAAGASASGPDPAAFGVAFFRTEYANNAAISQLPVPYVALIDGICMGGGVGASFHGAFRVATERTILAMPEAGIGLFPDIGASFFLHRLPGCLGRYMGLTGERLTGAEVKDAGFATHLVRSARIPELEAALVALGPRAADLSVVDNLIRSFEEPLVMAGAGAAGSLSSSALLEWKLPLINVHFGCGGVEEVIASLEGAVAAAEAAVQQPAAGSLEAAQAAFLKSTLAAMRRGSPLSHAMTWEMLRRSAAGHMTLRQALEMEFVMAARCVHGQADFLEGVRALLIDKDNKPAWKYGSVRQIPGEVVAALFEPLPGEGPLFGGSGSGSGSGPASRM
The following text describes a protein:
Function:
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
Subcellular Localization:
Nucleus.
Sequence:
MPKSQKQKKARAADFTKAKLKLGKGKQVANNATNTSYSSKTIALPNQRIRTENTAIPTTKSNLTLDDLIVRLRHYSPNTRKEALQGLRELLDAHRTIWRLNLGTVIHSCACLISDENPSVRKALKSFFSWFIPRVELSLLKPFCSIIIFFACSALSHIFADIRVDAIYIIDILLEVAPDCVVAGWPRDTRLDLQLNGSDSQPRNLPQQPGLRLLQLYLSLLSIGSDSAAPGLSSTSANQLSGNSKLAVLKSLARFIDAASSLDTQKTSKNQMPLWIFRSAFRKERDFETFRVLLTESDPPSQDESTSNSYTINSEHYDSTNSHMFERFSEAFLEPDSFQENLGNSSGAGGAESSGSSNQTTHSHPTPDNSLQLLRAMHPVMLSIFLDTAPTAFQSELGSTSPAITSSSSGATVSPSLELVNCVITSLHRLWQASMAADLDVETKDIKSLETILIKMSPYFVFGGDDIIPQGTELKHMLQNLNLMYCDLVSLLALAKPDCSNTVAIQLNRVGNYITRLLENKVISMNSSSGPMQPEAYRRIFPIVWSLLKHDLVQRENPKADRDSWASRVIEAFIDHLNGLSPNSELKFLGLNFLARLCILDDLPGCQIASELDILAPETQEKLRQWMMGLPKLLWQLGTKNPTTSHLVLSFLHRVVSRPMIFFEACLPDLGRLLVPFFSIDHPTSGRTLPGPYSRLPDSCRKLSEGICWYLLNQPALLLQSAPLRSALRVSNPSFEQSLICSS
The following text describes a protein:
Function:
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues. Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices. It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes. By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors. By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes (Probable).
Subcellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MGEVEISALAYVKMCLHAARYPHAAVNGLFLAPAPRSGECLCLTDCVPLFHSHLALSVMLEVALNQVDVWGAQAGLVVAGYYHANAAVNDQSPGPLALKIAGRIAEFFPDAVLIMLDNQKLVPQPRVPPVIVLENQGLRWVPKDKNLVMWRDWEESRQMVGALLEDRAHQHLVDFDCHLDDIRQDWTNQRLNTQITQWVGPTNGNGNA
The following text describes a protein:
Function:
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
Subcellular Localization:
Mitochondrion.
Sequence:
MLKTHTRNIPLIRRLARFNSTIARDPVTIIPTIYELTEAKDLTPETNPDNSLLEYLQSRHLIESITDDNLYKLTKRGSNHKFKLYCGADPTASSLHLGNLLPLMVLLHFKMSGNDVVGLVGGATGLVGDPSGRKTERNKIDEVEVEDNVTKIQRQISTFLSNGIEYAKSRQFPMTEKVGDTTSVNNASWWENVKMLEFLATYGRHIRVSSMLARDSIQSRLESGGIGFNEFTYQILQAYDFWHLYKDENVNMQVGGNDQWGNITAGIDLISRLKKFHGKKHEAYGLTVPLLTTSSGEKFGKSAGNAVFIDSSLTTPYQMYQYFINVPDDIVGKLLKVFTLLPLNVIEGELLPKHNSDPGLRIAQRVLAREVVDLIHGVGVGDEMAFITGFLFPTPDQPFNDNVSADKLIENFKRSGILFKRNKPSPDEEIKLSALLADIVGKSKGEMRRLIKAGGVYMGLDRNQIEDPDDVILFDVDNHLIDGKLLLVRVGKQNYYVVEFV
The following text describes a protein:
Function:
Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MRLENWPIVEMFRSRPGVPNWPKFGLFAVGVIGSAYLGYRYATPSEEDIVRRMNPELRERYMLERDARQEYFNEFVKEAIAQSKTNEPIWKVGPMASKPIDFNVAVREKMKEIEARNDQDRNERIKNELAAIAKKEEEEKNKKGWW
The following text describes a protein:
Function:
Integrin alpha-PS1/beta-PS is a receptor for laminin.
Subcellular Localization:
Apical cell membrane; Single-pass type I membrane protein. Lateral cell membrane; Single-pass type I membrane protein. Basal cell membrane; Single-pass type I membrane protein. Note=During mid-oogenesis, localizes to the apical, to the lateral and to the basal membranes of follicle cells. Apical membrane localization peaks at oogenesis stages 9 and 10A in columnar follicle cells overlying the oocyte while decreases in the most posterior follicle cells. Localization to lateral and basal membranes persists during dorsal appendage morphogenesis, although diminished and often absent.
Sequence:
MLELPFTTIRPNCRLRQNLGILIILQCVLTCYNFNLEQRLPIVKYGHPHSHFGYSVATHTIGEANGPNKTNCVLVGAPLDQNRQPNTTHSGALWRCPMTQRFDDCEQVITDGRRNFDSEILSPPGNDEIKEDQWMGVTVRSNPLQANGSGGKVIVCAHRYMYIVRENRYGQGLCYLLTNDLQFEEVHEPCKGRPVQRQHEDYGLCQAGTSAALLDDDTMVLGSPGPYTWRGSIWVTQVGGEYLQRDKTTYYSDHSDLNSPVDKYSYLGMSVTGGRFFGHMSYAAGAPRSEGHGQVVIFDKSTDNPIPVHSILDGEQFGSSFGYELATADINGDHRPDLIVAAPLYFTKTEGGAVYVYQNIQDTLPMKYTLKLTGPLESRFGLALANIGDLNKDNCEDLAVGAPYEGNGVVYIYLGSSQGLNSKPAQKIQASELGGTIPNGQPIRTFGISISGNTDLDDNSYPDVVIGAFNSSAAVILLARPIISIQTSVQRKELHNMDPNTPGCLDDPASNLTCFTFRACCSIEPYDEKNKELRLAYSVEAETFDHLKKFSRVFFFDRENKRTNVLSRVVRVHTNGRTECQAVTGYIKANTRDIQTPVRFRLKYSLVEPPLADSALVRLNPILDQTQAHVDFEGTFQKDCGDDDLCESNLIIRVEPNITESSGNEYTLILDETELEVRINVSNLADSAYEAQLFIAHQAGVSYVATKKPTNATCNSYNTTLVACSLGNPMLRDTTTFVTIRFQPKGLEPSEKIMLFHIFANTTSKLVGPERPERDLRVNVVRRAKLNFRGWAIPEQSFYSGSSVANSVANTAATDIEGHGPMGMDDVGSQVHHMFTIFNEGPSTAPKVQMVIHWPYSLYSDPQSGRPVQYLLYLEQVPTVEVSQGECHVAKEYVNPLNLASGSRENPAYLSAPAQMRMFPSQSRHSFNKSLIHSQRSYYSSSHRDDHSDDTQSNRNRVRRSFLERVTRLERLMYDPESSNAANGKKQDIVELDCNKGATNCVRIECDILNMPALSEAQVVVKARLWNSTLVSEYPRVERVRIFSTATAQIPESYGVEVMDHNNIEVETRAYPELRNQQRDTSIPWLIIILGIVGGLLLLALVTYVLWKVGFFKRIRPTDPTLSGNLEKMNEEKPFLAPSKNTHHVF
The following text describes a protein:
Function:
This is a dermonecrotic toxin. This osteolytic toxin, induces bone resorption. Potent mitogen. This toxin is associated with the severe progressive form of the atrophic rhinitis, a major respiratory disease in pigs.
Miscellaneous:
MISCELLANEOUS: Closely spaced cysteine and histidine residues may provide the toxin with an affinity for metal; MISCELLANEOUS: The sequence shown is that of strain NCTC 12178.
Subcellular Localization:
Cytoplasm. Secreted. Host membrane; Single-pass membrane protein.
Sequence:
MKTKHFFNSDFTVKGKSADEIFRRLCTDHPDKQLNNVKWKEVFINRFGQMMLDTPNPRKIVEKIINEGLEKQGLKNIDPETTYFNIFSSSDSSDGNVFHYNSLSESYRVTDACLMNIFVERYFDDWDLLNSLASNGIYSVGKEGAYYPDHDYGPEYNPVWGPNEQIYHSRVIADILYARSVWDEFKKYFMEYWQKYAQLYTEMLSDTFLAMAIQQYTRQTLTDEGFLMVCNTYYGNKEEVQITLLDIYGYPSTDIICIEQKGLPTPKVILYIPGGTQPFVEFLNTDDLKQWIAWHLKDNKHMVAFRKHFSLKQRQEGETFTGIDKALQYIAEESPEWPANKYILYNPTHLETENLFNIMMKRTEQRMLEDSDVQIRSNSEATRDYALSLLETFISQLSAIDMLVPAVGIPINFALSATALGLSSDIVVNGDSYEKRKYGIGSLVQSALFTGINLIPVISETAEILSSFSRTEEDIPAFFTEEQALAQRFEIVEEELHSISPDDPPREITDENLHKIRLVRLNNENQPLVVLRRLGGNKFIRIEPITFQEIKGSLVSEVINPVTNKTYYVSNAKLLGGSPYSPFRIGLEGVWTPEVLKARASVIGKPIGESYKRILAKLQRIHNSNILDERQGLMHELMELIDLYEESQPSSERLNAFRELRTQLEKALYLPEMEALKKQILQIPNKGSGAARFLLRTAMNEMAGKTSESTADLIRFALQDTVISAPFRGYAGAIPEAIDFPVKYVIEDISVFDKIQTNYWELPAYESWNEGSNSALLPGLLRESQSKGMLSKCRIIENSLYIGHSYEEMFYSISPYSNQVGGPYELYPFTFFSMLQEVQGDLGFEQAFATRNFFNTLVSDRLSLMENTMLLTESFDYTPWDAIYGDINYDEQFAAMSINERIEKCMNTYRGVAFQNSSKSIDFFLNNLTTFIDNGLTEIAISDLPYDIVQQEISQFLQGSNEWKTLDAMLFNLDKGDINGAFRKLLQSAKDNNIKFRAIGHSDNSVPPFNNPYKSLYYKGNIIAEAIEKLDREGQKFVVFADSSLLNSTPGTGRPMPGLVQYLKIPATVVDSDGAWQFLPDVASSRVPIEVTELENWQVLTPPQGKILGLKQFKLTAGFPTEQSRLPLLENSVSEDLREELMQKIDAIKNDVKMNSLVCMEAGSCDSVSPKVAARLKDMGLEAGMGASITWWRREGGMEFSHQMHTTASFKFAGKEFAVDASHLQFVHDQLDTTILILPVDDWALEIAQRNRAINPFVEYVSKTGNMLALFMPPLFTKPRLTRAL
The following text describes a protein:
Function:
NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins. NodD is also a negative regulator of its own expression. Binds flavonoids as inducers.
Sequence:
MDRFDAMRLFVRLVERQSFTAAAADLGIPRSTASEVLRGLESRLGARLLDRTTRHVTPTLDGEDYYRRCVAILAEVEEAETAMRDARPRGLLRIDAHPLLTRTFILPHLPAFLARYPQLDLQIGQGDRLVDLVREGIDCVIRSGEPEDSGMILRRLGTIAEITVASPAYLASHGVPRAPDTLDGHQMVAFVSSRTGDVLPLEFSVPGALHHVVLPSRVRVNNSDTMADLARLGFGLAQAPRYRFADDLASGALVEVLADYPPSPTPLSALYLQNRQPALRLRVFLDWISGIFAEAKL
The following text describes a protein:
Function:
Molecular adapter which is involved in cilium biogenesis. Part of a functional complex including OFD1 a centriolar protein involved in cilium assembly. Could regulate the cAMP-dependent phosphorylation of OFD1, and its subsequent ubiquitination by PJA2 which ultimately leads to its proteasomal degradation.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Preautophagosomal structure.
Sequence:
MWRNYGASADSFYQVRPECADDVPETKFRIKVGKTLSSRRWHAAFTPEGYLDIGKILGRVCRGGIHPSIRGEVWEFLLGCYDSKSTFEEREQLRQRRRVQYAALKEECRGMFPLIGSGRFISAPVITEDGDPILDPIVLQELNAAKEPTSAGQVGPSDGFELVKEHDKKVIQWKLSLHQIGLDVIRTDRTLVFYEKQENLSKLWDILAVYAWFDKEVSYCQGMSDLCSPMIILLDDEADAFWCFERMMKRLMMWSLEYDPELFSMYEEDPDLTAENSRRAKVKSIRQYGKYERENMRSGGKDTEAPLPISVFLVASVLKDKSAKLTEARGLDEVVKILNNITGHLDARKACSSAMKLHKKYLKKLNLNNKMKDKGVRYDEIILSFFYYGTNTSIPIGNSTINGFYQGHDKKAKKKGKLEIQKMAWDAAFKNVTNTSKVIFRVDLATRISYKTIFWFSKKHNFTVENRTMEVDSTEQRSKSGRSGNGFIPSSFRLLSRIVSSGASTVASTVRSAALAIVDRDNDHDQVLWAGFDKLECEGGMSRQILLLGCQYGFQIWDVEDSDNIRNLVSRPDGPVPFMQILPKPIASKKHEDKFSGSRPVLILYTDGCFSGGSNIREGIRKLHDQESTSFDPSIVWFYSLTCHSYVHQLKFKSVIHLVRCSSRVIAILQATQIHFFDAATLDKVYTVVTNPVITGFSGFGSKGVGPLALGARWMAYSGTPVSISNSGHVNPQNLTPSASFPSLAPNGSLISHYAKESSKQLAAGIVTLGDIGYKKLARYYSDLSPDSNCSQSGSACGKISGTANVHLPGADNVGMVIVRDIVSKALIAQFRAHKSPISALCFDPSSTRLVTASVHGHNINVFQIMPILSENKSPNPGSSYLHLYRLQRGLTNAVIEDISFSGDSQWIMITSSRGTSHLFTIPPSGTVNFQSSDAFVTGRSNGSSVLEKPAVHCTSNSKIPLLNQHNICESDPLVTLSAIGRIRSGSNGWRNTVTGAAAAATGRTISFSGSIASAFHHCNSTRQYADSGLLKANHCLLVFSSPGCMTQYALRMCSELDSIATFPAMGSTYEEDLETKLVVEAIQKWNIFQKQNYKERVDNADIYGEFGCSDSSKVFPEGITKGNSLSSETRDTFIKEKIRSELGHHIYISEAELQMHKPHNQVWAKPEVSFRSFVMDRIHLDDEGRGEAEVEVIPTRMVEAKSKRLFPALNFTMAEEPRRIMLERHAKRVVPL
The following text describes a protein:
Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Required for mitochondrial morphology.
Miscellaneous:
MISCELLANEOUS: Present with 26000 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Sequence:
MTSLSSQPAYTLVFDPSPSMETYSSTDFQKALEKGSDEQKIDTMKSILVTMLEGNPMPELLMHIIRFVMPSKNKELKKLLYFYWEIVPKLAEDGKLRHEMILVCNAIQHDLQHPNEYIRGNTLRFLTKLREAELLEQMVPSVLACLEYRHAYVRKYAILAVFSIFKVSEHLLPDAKEIINSFIVAETDPICKRNAFIGLAELDRENALHYLENNIADIENLDPLLQAVFVQFIRQDANRTPALKAQYIELLMELLSTTTSDEVIFETALALTVLSANPNVLVPAVNKLIDLAVKVSDNNIKLIVLDRIQDINANNVGALEELTLDILRVLNAEDLDVRSKALDISMDLATSRNAEDVVQLLKKELQTTVNNPDQDKAMQYRQLLIKTIRTVAVNFVEMAASVVSLLLDFIGDLNSVAASGIIAFIKEVIEKYPQLRANILENMVQTLDKVRSAKAYRGALWIMGEYAEGESEIQHCWKHIRNSVGEVPILQSEIKKLTQNQEHTEENEVDATAKPTGPVILPDGTYATESAFDVKTSQKSVTDEERDSRPPIRRFVLSGDFYTAAILANTIIKLVLKFENVSKNKTVINALKAEALLILVSIVRVGQSSLVEKKIDEDSLERVMTSISILLDEVNPEEKKEEVKLLEVAFLDTTKSSFKRQIEIAKKNKHKRALKDSCKNIEPIDTPISFRQFAGVDSTNVQKDSIEEDLQLAMKGDAIHATSSSSISKLKKIVPLCGFSDPVYAEACITNNQFDVVLDVLLVNQTKETLKNLHVQFATLGDLKIIDTPQKTNVIPHGFHKFTVTVKVSSADTGVIFGNIIYDGAHGEDARYVILNDVHVDIMDYIKPATADDEHFRTMWNAFEWENKISVKSQLPTLHAYLRELVKGTNMGILTPSESLGEDDCRFLSCNLYAKSSFGEDALANLCIEKDSKTNDVIGYVRIRSKGQGLALSLGDRVALIAKKTNKLALTHV
The following text describes a protein:
Function:
Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway, the deacetylation of N-acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN-Mal). Has weak activity compared with bshB1.
Sequence:
MERHVLVVFPHPDDEAYAAGGTIRLLTDQGVPVTYACGTLGQMGRNMGKNVFANRETIPHIRKKELKDACEAMGIKDLRMLGFHDKTLEFEDVDFVADKIEAIIQEVNPSRIITFYPEHGVHPDHNAFGRAVVRAVSRMPKEERPVIHAVAITKNREAVLGEPDVVNNISEVFDHKLTALGAHRSQTEAMLEDTHAKIKNKDAATLKWLQLEQFWTYKWE
The following text describes a protein:
Function:
Involved in osmoregulatory glycerol response, probably through its interaction with PLC1 which regulates the expression of GDP1.
Miscellaneous:
MISCELLANEOUS: Present with 3060 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MQKTDGIRIPGVILDELKTLDYSQDERFSISEGKKRRRGNGKHLSRKEKRKMERADKKRKIISTREINSSRLKSAPTSEKRSANAGVKNVGKQANGKNPISSDESESNENWDSDEVLTDEVAEESGEQAMSAEETMKKLESLKRKAKGIQGAENSGEIKGNSYEKKHIRNRDTNENFVSYPLAPSDRSAFERDEMDMQYYAKKLGLKGERKAIHAKDEFDAIGGLLEGLEYFENYGKSDEEYGDFATETNSMRKDDEASEKAFSSDDDLSASDFEDSDGLSESDNDSVADSDDNYRREKENPYVAPTQSVESYVPPSLRKKLDDSENNSTLSEISKKVNSSLNKLSDSNITIIITDLNRLYDSLPRQYVTESLTKGILNIISQNQKLLDGFIMNYAALAYTLSKLRGIEVGAFFIQKTVEAFLHHYEEEMENILKDQQSKISSKICINIATLLSYCYNFGFVSCRLIYDIIRIFVADPNEFTTELLLRIISISGQLIRGDDPSALRDIRSELLKNAKNLKEQSPRLRFLMDTMSDLKNNRLKPSILATDHHPLKKNLQSILNSSSSWEPLQVSLEDIKNIDSKGKWWLVGASWRGNMENAFEVSINNENDASKSKKSKISIEDDLLDDIPDWNIIARQQRMNTDIRRAIFISIMSAQDYLDAFSKLEKLSLKNKQVLEIPRIVLHCLLADSGSNGYNHYYALVANKICERYSHLSKSFQFLFWDVIKKFEDKEFDSESDTDEEDDLDDKEKLLRISNQGRFFGSLLANDILKLDVFKHVPFMGGLNTEGMLFMEILLFQLFLTVAKKSEKKLKMDESGNKRIIYSDDYLRDVLTKNVKSENMLFILKGLKWFINKKFRYHNFLAGKKGDKAFDRDERRLAWASKAAKSIIDKELENIDS
The following text describes a protein:
Function:
Probably binds and transports small hydrophobic volatile molecules.
Subcellular Localization:
Secreted.
Sequence:
MKTLFLGVTLGLAAALSFTLEEEDITGTWYVKAMVVDKDFPEDRRPRKVSPVKVTALGGGKLEATFTFMREDRCIQKKILMRKTEEPGKYSAYGGRKLMYLQELPRRDHYIFYCKDQHHGGLLHMGKLVGRNSDTNREALEEFKKLVQRKGLSEEDIFTPLQTGSCVPEH
The following text describes a protein:
Function:
The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. The enzyme II complex composed of GatA, GatB and GatC is involved in galactitol transport. It can also use D-glucitol.
Subcellular Localization:
Cytoplasm.
Domain:
The EIIB domain is phosphorylated by phospho-EIIA on a cysteinyl or histidyl residue, depending on the transported sugar. Then, it transfers the phosphoryl group to the sugar substrate concomitantly with the sugar uptake processed by the EIIC domain.
Sequence:
MKRKIIVACGGAVATSTMAAEEIKELCQNHNIPVELIQCRVNEIETYMDGVHLICTTAKVDRSFGDIPLVHGMPFISGIGIEALQNKILTILQG
The following text describes a protein:
Function:
Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1-diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P). In vitro, has low undecaprenyl-diphosphate phosphatase activity.
Miscellaneous:
MISCELLANEOUS: In E.coli, lipid A contains typically a monophosphate unit at positions 1 and 4' (bis-phosphorylated lipid A). However, one-third of the lipid A contains an unsubstituted diphosphate unit at position 1 (lipid A 1-diphosphate).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Note=Transferase activity takes place on the periplamic side of the inner membrane.
Sequence:
MIKNLPQIVLLNIVGLALFLSWYIPVNHGFWLPIDADIFYFFNQKLVESKAFLWLVALTNNRAFDGCSLLAMGMLMLSFWLKENAPGRRRIVIIGLVMLLTAVVLNQLGQALIPVKRASPTLTFTDINRVSELLSVPTKDASRDSFPGDHGMMLLIFSAFMWRYFGKVAGLIALIIFVVFAFPRVMIGAHWFTDIIVGSMTVILIGLPWVLLTPLSDRLITFFDKSLPGKNKHFQNK
The following text describes a protein:
Function:
Involved in pre-mRNA splicing; Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation.
Subcellular Localization:
Nucleus.
Sequence:
MISATQPLSRDVAVPLSDAEREKRREEEPKKQSREEWRKKKELEEARKLGNAPAEVDEEGKDINPHIPQYISTVPWYVDPSQRASLKHQRCQPEKQVEFNKMNDWYRRGVADKPIATKFRKGACANCGAMTHKKRDCLERPRRVGAKYTGEGIAPDEHLQPDLNLDFDGKRDRWNGYNPNQHKEVIEEYKKIEIAKQTVKAKKLQEELISGKMEEGGSDDEDKYADAASMPGTNFDSKQRITVRNLRIREDTAKYLRNLNPNSAYYDPKTRSMRENPYEGSGKAAAEGDFAGDNFVRHTGDTHAMARTQMFAWEAGDRGVEVHLQADPTRLEMLQKSFHVRKDEFKKDEQQSILAKYGGLEHLDAPPKELLLAQTEDYVEYSRQGNVIKGQEKAKTKSKYIEDVYVNNHTHVWGSYWQAGVWGYACCHSTVKQSYCTGEAGKATKKIEIPLTTNNENKKETKLEKLEKKHSAWTKALGIEHKVQEDGGGGSEGDGGDRGDDMEGEEGTSGEEDQPKSLLQVSVMIVVGLSLRSSQLFYIHPSLSFIMFCSFCVYLVTLGLLYGLFTAT
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular Localization:
Mitochondrion inner membrane; Lipid-anchor.
Sequence:
MGSSGSSQGRRKVSFELDEEDRVRVLQGIRLSEDVVNRMKQPCQTKKDQRAPPIPPSPILQPAEGKSKVPTGISPPTPDSLGRKPSEAEEELYKRYEQEQAMVQEELLRLAKREREAATESLNVTLQRERSNTNEEKQKTSQIPADLDAWSKELQWKDEELKRRDTFYKDQLAHIEKKNSEIYKMTLSQFSDAVTNAEDRIRRRNTQPICANLQEAILTCYNENKHQVLNCSDLVKEYQRCVRLAQKHFGKASDRGSFTFPLP
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence:
MEDLSAKKREIDEKLQMETQKLAFLKDSLNKSNQLTENMVSILESFSSRLHKLEDTIVPVHRDTKNLQKLQDNIDKTLSSLDHVISFYNVAKDVEQTIREGPYGSPDPLAPKYPDRESDNQPSDGPTGRLDSYLQSMARVQNAVDFFSTNNPGSPELHTVTQLFESGKDQLEREFRNLLTRHSRPVPAVTILDMLGTEDDPEDIPLEHLPERTVAELTEISRWLITQNSTDFMNVYAQIRSNTLLRSLDGLKEHQAKTGTATGVSPASGGSRKLALKDTPTKKTAYLKGRTIIRKAGSSIMKHSSLTLDTARRQGSNVVAELKDDVSDTETDTCILCISALLKLMQSESKLMEGVIPERYHNSIFEQLVQQSMDGVVADVENIATSAKRCIGKHDYSAVLSIFPVLKHLRAINPDYEEALKGTKQGQKLPSLMSTLDTTGAKALEEFIDSIKNDPDKQSNMSKDGTVHELTSNAMIFLQNLLEYLHTAGGMLAAQVAASWCPVDIYPAGMKAAEINERKLSIYIGKVLGALQLNLENKAKGYDDPALTAIFLLNNYHYILKTLKSSGLMRVVVLQTSDIEEHYEDIIREQKRLYSKSWSGVLRHILEISGKTVSQQRAAPQMGKKFKLKDKERQTIKDRFKGFNQEFDDIYRTQKGYAIPDQELRQTLRNDNRDFILPAYTAFREKYEPMQFTKNPEKYIKYSPEEVSATIDRFFDLSA
The following text describes a protein:
Function:
Intramembrane glycolipid transporter that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. RFT1 could mediate the translocation of the cytosolically oriented intermediate DolPP-GlcNAc2Man5, produced by ALG11, into the ER lumen where dolichol-linked oligosaccharides assembly continues. However, the intramembrane lipid transporter activity could not be confirmed in vitro.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MIDENNKLKKRIKQEIDNNNNNSNNNNNNNNDNDIKLTTNDSNNKTQQQSNVLQSGFIGAIYLIGLQIISRVFTFILNTLVIVGVDDSILGVSAIQYQLLSSIILFLSRESIRRACSRTNIQESKENLKSVINLSWAILPIGILLSIVFENFFLYTSNKETLMIPNYHYGLRLFTISAILELLSEPMYILAQNLLLFKIRTSVEGFALFFKTLSTYYFIVILKLGLKGFGYSQILYSLVLVFGYFGYFLFNVSKNSGNSNLKIFTSVNQLFPSFTTIDRGLIKLSVIYTWQSIYKILLTEGEKFVLYFSETNQGQAIFAVVSNLEETCFLMFPKLFNSNNNNNNNNNNNNNNNGSSNSNNNYKVGAGVLIVMMKFLILVALVFTCFGPGFSDLLLNLLYKNKFKDSNAGVLLGFYCLYVGFLAVNGVSEAFVHSVAKESQLKIVNLVLVVIGVIYLLFTLLLCKLFQNIGIILANCLNMLLRIIY
The following text describes a protein:
Function:
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
Sequence:
MHSYTLHAPAKINLFLEILGDRPDGFHELVMVLQSIALGDKITVRANGTDDIRLSCGDSPLANDATNLAYRAAQLMINNFPQAHDNYGGVDITLTKHIPMAAGLAGGSADAAAVLVGLDLLWNLGLTRPELEQLAAQLGSDIPFCIGGGTAIATGRGEILDPLPDGNCFWVVLAKHRSIEVSTPWAYQTYRQKFGKNYLNDDQSQRARRKTIHAGPLLQGIQHRNPGQIASHIHNDLEKVVLPAHQPVAQLRQVLQSAGGLGTMMSGSGPSVFTLCREQAEAEQVLAIAKEKLNDPDVDFWLTHTIGHGIQIMNN