lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the retro-aldol cleavage of 4-hydroxy-2-oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of 3-phenylpropanoate.
Miscellaneous:
MISCELLANEOUS: Presumably stereoselective for the 4S-enantiomer of 4-hydroxy-2-ketovalerate.
Sequence:
MNGKKLYISDVTLRDGMHAIRHQYSLENVRQIAKALDDARVDSIEVAHGDGLQGSSFNYGFGAHSDLEWIEAAADVVKHAKIATLLLPGIGTIHDLKNAWQAGARVVRVATHCTEADVSAQHIQYARELGMDTVGFLMMSHMTTPENLAKQAKLMEGYGATCIYVVDSGGAMNMSDIRDRFRALKAELKPETQTGMHAHHNLSLGVANSIAAVEEGCDRIDASLAGMGAGAGNAPLEVFIAAADKLGWQHGTDLYALMDAADDLVRPLQDRPVRVDRETLALGYAGVYSSFLRHCETAAARYGLSAVDILVELGKRRMVGGQEDMIVDVALDLRNNK
The following text describes a protein:
Function:
May be involved in plant development processes.
Sequence:
MLGAMESRMDQYEIMEQIGRGAFGAAILVNHKTEKKKYVLKKIRLARQTERCRKSAHQEMALIARLQHPYTVEFKEAWVEKGCYVCIVTGYCEGGDMAELMKKANGTYFPEEKLLRWFAQLALAVDYLHSNYVLHRDLKCSNIFLTKDHDIRLGDFGLAKTLKADDLTSSVVGTPNYMCPELLTDIPYGFKSDIWSLGCCMYEMAAHRPAFKAFDMAGLISKINRSSIGPIPTCYSPSMKTLIKSMLRKNPEHRPTASDILKNPYLQPYVDQHRAFTAIPHPMRSPGKSITSSRSSRKSMSGSQCSSISGTGSDLDSIQSSERNTSGLATSSNNTTIGTEGAEATDDASVKTCSTPRELKSRKDIDSPELERQDSSKSIHDDQRSKYGSKQPKIIKKILTTLREETSKLRVNNSPLRASRVKLHSPSHRELLSDDSEHNSVSSSVKSSEVTPHAPAKVNRDTVKHIQASPPLKYLSPIVEHSPKVKIKVDELQQLDPTKQTIEDVDAAEGKVKNRVLLLPSFSRRPSFPPRRQVGTESPQHTGTKRAHSKVTAEHAKSPSRPVHSPKNVITEFPGVLMAPPSPLGGNQMKVGNSQAKCAPPRDVATKEVSTACSSSKIDYADSIKQSEEPSEPDSLTSFVSSCKCSTPDAVIQKHDLADMPSSELNTTNLQKSMVSNDDISVSSALDPSIDTNVQEFICKDDTPIITVQSDEDKFTVQELLSSVPYIAPYDSSTKTIALDKGSNSINQSSEKSPVSHLGPPVEDIIHVIRHSGFSVSGEQAVTGNAEMEAQSTDVSELRDVIKEEVDVRSITPSLTPSGLVGSAALKPNVSEDNTISPKLANSNVVKLPSTPEVNFTSPEANDMFKEETTPTKEIPATSAKEMLDVKSFRQRSEALEGLLELSADLLENNRLEELAVVLRPFGKAKVSPRETAIWLARSFQGMMNDEASRSST
The following text describes a protein:
Function:
Bacteriolytic activity against Gram-positive bacterium M.luteus and thereby probably protects against bacterial infection. Also has chitinase activity. May act as an ispopeptidase, cleaving isopeptide bonds between the side chains of Lys and Gln residues in proteins or in the cross-linking peptide of peptidoglycan in bacterial cell walls.
Subcellular Localization:
Secreted.
Sequence:
METVSVEEGLDFAPGMVSQKCLLCMCKLESGGCKPIGCRMDVGSLSCGYFQIKQPYWIDCGKPGKDWKSCSNDINCSSKCVQQYMKRYATHYRCPLNCEGFAREHNGGPNGCHSSRTLKYWELLQKIPGCKGVKFS
The following text describes a protein:
Function:
Involved in the biosynthesis of sulfomenaquinone (SMK, initially named S881 on the basis of its mass), which is localized in the outer envelope of M.tuberculosis and negatively regulates its virulence. Catalyzes the hydroxylation of beta-dihydromenaquinone-9, leading to the formation of omega-hydroxy-beta-dihydromenaquinone-9.
Subcellular Localization:
Cytoplasm.
Sequence:
MTATQSPPEPAPDRVRLAGCPLAGTPDVGLTAQDATTALGVPTRRRASSGGIPVATSMWRDAQTVRTYGPAVAKALALRVAGKARSRLTGRHCRKFMQLTDFDPFDPAIAADPYPHYRELLAGERVQYNPKRDVYILSRYADVREAARNHDTLSSARGVTFSRGWLPFLPTSDPPAHTRMRKQLAPGMARGALETWRPMVDQLARELVGGLLTQTPADVVSTVAAPMPMRAITSVLGVDGPDEAAFCRLSNQAVRITDVALSASGLISLVQGFAGFRRLRALFTHRRDNGLLRECTVLGKLATHAEQGRLSDDELFFFAVLLLVAGYESTAHMISTLFLTLADYPDQLTLLAQQPDLIPSAIEEHLRFISPIQNICRTTRVDYSVGQAVIPAGSLVLLAWGAANRDPRQYEDPDVFRADRNPVGHLAFGSGIHLCPGTQLARMEGQAILREIVANIDRIEVVEPPTWTTNANLRGLTRLRVAVTPRVAP
The following text describes a protein:
Function:
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrium between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
Subcellular Localization:
Cytoplasm.
Sequence:
MIIKREMRQDKRAQPKPPINENISAREVRLIGADGQQVGVVSIDEAIRLAEEAKLDLVEISADAVPPVCRIMDYGKHLFEKKKQAAVAKKNQKQAQVKEIKFRPGTEEGDYQVKLRNLVRFLSEGDKAKVSLRFRGREMAHQELGMELLKRVEADLVEYGTVEQHPKLEGRQLMMVIAPKKKK
The following text describes a protein:
Function:
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Does not accept 4'-phosphopantothenoylcysteine as a substrate.
Sequence:
MAILDDYSTLSPPNSYAAVVLGGTFDRLHDGHRQFLKAAAVLARDRIVVGVCDGPMLTNKKYSYLIETIEERTKNVKDYIKSIKSELVVQVEPIVDPYGPSIVDDNLEAIVVSKETYPGGLSVNKKRGERGLSQLKIEVVDLVPEESTGEKLSSTALRRVEAEKHSKSNA
The following text describes a protein:
Function:
Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity. Also acts as a coactivator for HNF1B-dependent transcription.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAFGFMTRVALQAEKLDHHPEWFNVYDKVHITLSTHDCGGLSERDINLASFIEQIAASLS
The following text describes a protein:
Function:
Involved in cell wall metabolism and required for the separation of the mother and daughter cells.
Sequence:
MRLSSLGEATAGSAAPAVVCGSRTDLYIACSCTEGQCSRADSMALNERGMQMDRGQARPAVRQPDERERKQRLVNRCFRESRVPDSESSPGTERRTAELSGFYTTKKLRSLYWTLRTDASLTAFAVAQERDTILISNRHHSEENLKLYQYDNVKSKLRRIQTITLPGGSVVACALPGPGFNVVMGEALRRTHDQLILTGHEDAVVNLIATSLEEGDARIIRRFNPAKYLRRLRAQYGDEAADMPWLQEIDSLRVRQLTPWRSVKTDATGFIALVNELIFIYTFDDTREPLYMHHFPGVESFDVNPENELLLALSGSKYGANGISLLDLTKMRGIGRQYAPAGHLKAFERAADSKHCLWLDKSLLVNSVGNILRVWDIRCSTGLKCEVLGHKSNITAVRYHKNSHTLYSCDEDGYIFSWELSHLLRELEGMTDVRRMTLCRSPQSIKTADDCSTTIQCGNIVVAPDTEFSSKRNSSVRSSSSRLGRLHLQFLGDGTLITLDALELGVHKVQDAKCYIAPSKNKLRRHSELPIKTLAPSAVSHAVESDSSLSSDSTLVERAQLEELHHDIFGSGFMSLDLHAEVDHS
The following text describes a protein:
Function:
May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found. May be required for rapid internodal elongation in deepwater rice during submergence (By similarity).
Subcellular Localization:
Secreted, cell wall. Membrane; Peripheral membrane protein.
Sequence:
MASRFQLILSTFVVIAAVTMLPRPCASIEFHRKLSSWSNGGATWYGAANGAGSDGGACGYQGAVFQAPFSSMIAAGSPSIYKSGLGCGSCYQVKCTGNSACSGNPVTVVLTDECPGGPCLSEPVHFDLSGTAFGAMANPGQADQLRAAGVLQIQYNRVPCNWGGVKLTFVVDVGSNPNYFAVLVKYENGDGDLSGVELMQTGAGAAWTQMQQSWGAVWKLNAGSALQAPFSIRLTSSSGKTLVASNVIPSGWKPGMSYISTVNF
The following text describes a protein:
Function:
Reduces the stability of FtsZ polymers in the presence of ATP. Required for cell division under low-oxygen conditions. Hydrolyzes ATP but not GTP.
Miscellaneous:
MISCELLANEOUS: ZapE abundance has to be tightly regulated to allow cell division. Loss or overexpression of ZapE alters Z-ring stability and leads to bacterial filamentation.
Subcellular Localization:
Cytoplasm. Note=Localizes to the constricting Z-ring during late stages of the cell division process.
Sequence:
MQSVTPTSQYLKALNEGSHQPDDVQKEAVSRLEIIYQELINSTPPAPRTSGLMARVGKLWGKREDTKHTPVRGLYMWGGVGRGKTWLMDLFYQSLPGERKQRLHFHRFMLRVHEELTALQGQTDPLEIIADRFKAETDVLCFDEFFVSDITDAMLLGGLMKALFARGITLVATSNIPPDELYRNGLQRARFLPAIDAIKQHCDVMNVDAGVDYRLRTLTQAHLWLSPLHDETRAQMDKLWLALAGGKRENSPTLEINHRPLATMGVENQTLAVSFTTLCVDARSQHDYIALSRLFHTVMLFDVPVMTRLMESEARRFIALVDEFYERHVKLVVSAEVPLYEIYQGDRLKFEFQRCLSRLQEMQSEEYLKREHLAG
The following text describes a protein:
Function:
May have a role in bone formation and also in establishing the ordered structure of cartilage through matrix organization.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix. Note=Surrounding resting, proliferating, and hypertrophic chondrocytes.
Sequence:
MGMLARVALGLIIIDAVLAAPTTELFNYDSEVYDAILEDTGTFYNYEHIPDNHVENEKVSERLSGNRELLTPGPQLGDNQDEDKDEESTPRLIDGSSPQEPEFPGLLGPHTNEDFPTCLLCTCISTTVYCDDHELDAIPPLPKKTTYFYSRFNRIKKINKNDFASLNDLKRIDLTSNLISEIDEDAFRKLPHLQELVLRDNKIKQLPELPNTLTFIDISNNRLGRKGIKQEAFKDMYDLHHLYITDNSLDHIPLPLPESLRALHLQNNDILEMHEDTFCNVKNLTYVRKALEDIRLDGNPINLSRTPQAYMCLPRLPIGSFI
The following text describes a protein:
Function:
Catalyzes the reversible interconversion of L-ornithine and 2-oxoglutarate to L-glutamate semialdehyde and L-glutamate.
Sequence:
MFSKLAHPQSLAVLRRGVHASVTSATSVATKKTIQGCSPEYIYEREAKYGAHNYHPLPVALEKGKGVYVWDVEGKRYFDFLSAYSAVNQGHCHPKIVAALKSQSEKLTLTSRAFYNDVLGEYEEYITKMFKYNKVLPMNTGVEAGETACKLARKWAYTVKGIPKYNAKILFAVGNFWGRTLSAISSSTDPSSYDGFGPFMPGFEVIPYNDLPALERALQDPNVAAFMVEPIQGEAGVIVPDKGYLTGVRELCTKHNVLFIADEIQTGLARTGKMLAVDHENVRPDLILLGKALSGGVYPVSAVLCDDEIMLSIKPGEHGSTYGGNPLACRVAMASLEVIEEEELVKNAETMGNLLRNELMKTPSDVVTNVRGKGLLNAIVIRETKDYDAWKVCLRLRDNGLLAKPTHGDIIRLAPPLVIKEDEIRECIEIIHKTILSF
The following text describes a protein:
Function:
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
Sequence:
MLSFMKIRRNPTRPVTIGSITIGDGHPIAVQSMTATKTQNIDATVEQAEALHARGAGVVRIAVDSDKDAEALAEIRKQTQANLAVDLQENFRLAEKVAPHVDKIRYNPGHLYHHARELTWQEKVRYLIDTAGSNNCAVRIGVNCGSVDPAKKEKYDHDDSITPMLESALEHCELVDSLGFHNFVVSLKDSDPSKVVQVNTLFAEKRPDVALHLGVTEAGMPPDGIIKTRIAFEQLIGKGIGDTVRVSLTLPNPRKPEEIDAGKQIVEDIHAGRVRSVVKFDDSKLNIISCPSCSRVENEAFIDLAAKVKEMTTFAQEYSITIAVMGCRVNGPGETDDADLGLWCGPAKVNLKRGPEALGAFGYDEILPKLKQELDDLIAAKQ
The following text describes a protein:
Function:
S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase.
Sequence:
MAAPGDNFSSPTAESLHRKTGSRKTAPKDYKKKKKPKPKPVTEVRVDRSVISKLHVLNKELDTVRSDQSLSQGTKQARVNKLETEIQKMGGLDAYQAASKRGACCHGNTTTSNWVIKQLKKFKVKPASEIKRLRLLDVGALDNHYHRHGWLDCTAIDLNPQTDRVTKADFFHYQVEEGQEYDVVVLSLVINFVGDPKKRGDMLRHCCHVTKENGHLFVVLPLPCLSNSRYLTHQLFCDMLHSLGFQKLRCHDSKRLSFFMFQRIGKRRSKSFPKQVVRTGPNHNNFSIVL
The following text describes a protein:
Function:
Transcription factor, involved in positive and negative modulation of transcription. Binds to multiple DNA sequence motifs in the regulatory elements of target genes, including homeobox selector egl-5 and LIM homeobox mec-3. Involved in cell-fate regulation in multiple lineages, including neuronal, mesodermal and vulval. Required to regulate the fate of PLM touch receptor neurons, acting via negative modulation of transcription of egl-5 and mec-3. May modulate gene expression by interacting with different transcription factors during neuronal and mesodermal cell development. Promotes the proliferative sex myoblast (SM) fate, in a cell autonomous manner, acting via the SoxC transcription factor sem-2. Involved in vulval cell-fate determination, acting by regulating expression of homeobox protein lin-39, and may link lin-39 to incoming signaling pathways. Plays a role in detoxification of reactive oxygen species (ROS), by regulating expression of transcription factor skn-1 and the phase II detoxification genes.
Subcellular Localization:
Nucleus.
Sequence:
MNELLAEMAAVSSRRKQSKPRRMSGEGDAMMSPIDLSTKSFDENNCEKGAGGALPLEDRSNILPHFSVPFANPQQFLSLCAQLGNSSSRNVSSTASTTSSCPIQSCSQSFSSPAALTWHVLDAHEDEQEIFSCDVCTTTFSNGQDIREHKCQKTLASRSTSVPPSTIPSSVCFLSTPTTPCLQFSINESIGTSEIREEDEEEDMDVEDGEHVANQLFGHLLQKSDDKSKMASLFNHAFPPFAAFPNMPPPFLMRQPFDPRADVFAAGRHDNDDDWEALMEISTSDEAEKIRALVGDKAVPTTDPNQCILCRRVLSCKSALQMHYRTHTGERPFKCKICQRAFTTKGNLKTHMGVHRSKHSFRGLPISLPPQLAAMHQHQHQIAPPQRIHIHNPPTSAASAAAAVAQIQASQQCPICQQRFLNAGELAVHITEHRNSLTQPPRVMPTPTTTRVQTFPFVPFFTTPPSLNATDMSTQFNLANILSAQLKNDSSPNTDTSSVEEKITRDDPPKMASLSPSNSSDSSSSVRQDILESSEFEEKLKKLEEPPILEQQVSTTPNPKNENPLLAMQKMWAETEPPPPRQMPVLSKHQCGVCFKHFSSSSALQIHMRTHTGDKPFKCDMCGRAFTTRGNLKVHMGTHSWQQSPSRRGRRIFDVASSVTEKPMLQSPILPTSGAPGASPLAMLGPNGLSGLEMMMMLWRTVCSVCQKVCQSPNELEQHLKEHLNNGSSAAPTPLASAATPPPS
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence:
MSIRRYSGNSPRINDYDSRTVDESLYSLKEVYNTIKYDWPQMLREDANPIEMAVALLDDTSVGLAHRLQEFNMLKESSEQALRSVVNEHYDLFNKSMGSYNTLLSTMKNSQEDSLEIKNFLEYSNKEVHDRSAVLGELSSASAKYSEMIEVLDAMAEMNEIPGKIDQLVIDKKIHEVYDVISEGYKTAEKYNLWSLPAMNGIKTYLEEQSNKLFDMIIDELQNEIYLKYNRNPQEGAIAWQNIIHSSNPQLTSFVTLLDSKNLEQFIFNSANLDISEVVDFLTSPVKNFIVNQLPDLHAHNSKNDGVIDYKILLDSTSNPNTESFYYIYMLLLTASKLNRLNQAVEVLLDTNQSELHGLINRTTEAVKSRNGHALSKLSKMQHLDHGSLFDVIVHGSFSDSAVVLLQDLFGSIFIRCLATFQRHKVITQIVTLLQEGKAPSTPKAVAESTPTFDSPQMGRPDTFHARNLFTIWKTIQKELKALMLNYIYDDHNYKLHSLADTTGATNRNKISNALGKKELFKFEDVTYNPSNKTTKEILDVLADVFPGYSISDDNNNGAIIETATPYVKHESFNATVEVLVPKNLFNMRIILEFFLIFIDGSQRIFFDFEDEKTRGVHARTSFHFFEDFMKISFLSYLRNTIEFNFGEQVGGAYSMKIEQAMPVNSGLKLDLISLSQDSNFKILGNAVSNVESNLIIYENAYNFKKMFLELCLILNTSLSYRENFSGAVLKTLENFSNEYNKLYQELLSTGEGTNIVRPPSRVSKWMKIPVLTEISGKILQRGVQGETANELQELIESESKVVLHDETVTHQEDLLDHEAYAQIVYLLLTTTWILSWLPLVKKESNYSIYDDEQNKTIKVSTVDKLRYNWSFLENGRQAINFTPDGTDIVQYNIYLALNSEKIGEFNNIIHNFESIRDKTLLALRYELRCKAVYFVTMSFKHVDWCPVTEPGDADHFIVNLNQEIFAMDNKLSKTVSDIERESIFLGFSQFLNDLIITRSKAVRKINSNGIKRILLNISTVQQMLRNLSSNPETIDFTKASEYFEMFTMNEFNLLKFIKSKRDNYTKDAYHTLARLIYSEKLADGNGSSFNKGKYNDLIKKIDGIFD
The following text describes a protein:
Function:
Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MRNLALIDKKSASCSFLKGCCAATVERNCMYFANQNELCKLDVDQKNAEDNVEILGPLDVGTVLDLKYLPEEDVLAIVAKMGSVSVYSLNSSEFDVVGDVSDGISACCWSPDMETLVIISETGNVLMMSRTWDVLQEVPLFQQDFGEAKFVSVGWGSKETQFHGSEGKDARSKKKIECTLADWDDKQTRIVWRADGLFFAINAVEPSMGHRLIRVFNREGFLQSTSEPVNQLEQSLSWRSSGASGLITSSVSLVQQGKQQMAFFEKNGLRHGEFDISVGHQVLESYWNGDSTILAVLIRFDQENYGLQLWTMANYHWYMKHFSPFEKGIRPLWITWDVIETNRLHVITSNGTYLMMDYQSVVTSSKGLTSSDPACIAVVDNCKLKITFLREAIVPPPMCGWEIEFSTSIHSLDLMSSDSTRLCVLTQNGQLHFFQLTNCEQGEKSCHPDIKIICKEGGRFQPIWDYTASLDLPDYVELHHFRLLNASTIVASSMNKLVVLNIGDSIITIKDSITVDFRIGGLESLREKGDTVLIHLIDGKILELHTNDMILSDSIVFPEFCYRLESINGHVIGLAASGRLYVDGKEILSAISSFVIHSDFLVVTSLQKHRLLCLPLAHISNSNLAITERAIERGAKLVHAVASETTVVLQMPRGNLEAIHPRALSLNIMKSLIDGKSFAAAFDLMKKQRINLNLLYDHNPSAFLEHCSQFVEQVSCVDVANLNLFLGELQNEDFTTTMYQNHYEEKSVPKDGEKVDRICNKLREVMFESDSQQYLLPVVTSYIKQGMVDAALKRVQVLAEESLKDQALKYMAVLVDGDQLYKEALATYDLQLTLMVAHRSQKDPKEYLAFLNELKAMADENERRFTIDNSLKRYDSAVRHLCRCRPIRTEQITSYMRLHRVYVSVIDELCNVLPMSEVKEALQAAACLQAEILVSRENHEEAGYLYQRVGLYNLAVDSFKQCGLWENCLSIASFVQMSDVDTKSLVTILVTRLRSLKKHKDAAHLAEYNLKDYQLTGQCLIDGLFFSEAWALAYRHSMDNWAETTLKNELEGALQMMEGKLEQVGNDCSKYTQRLSVVRQDLLYKRDHPPTETDHGDLYSETGSSIFTHTTGTSGKTFRSSKNRRKQERKKLRLKEGSPFEDMAIINELHVLYSSMSSVLQDVGRLLRGDLLISKDWSRAKCFQSKAELLVKKMEDKKKDIWNFSLIHKNQENDKNFGPSATTEMIISQVNQEKEEFFSTRYLELDPKLRSPPDSPDASWKLDSLK
The following text describes a protein:
Function:
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MKLMILLLTLGLLAGAQARSLFRDAPKTKWETALDSFWLTVNKMEEAADEARAKMKDSPISKELDGLIKDTMEELSIYAEDMKSKVSPMAQDAQQRFTEEVSALADKLKSDMEDTKNKAIQYSGDLRMMFDQNIEDVQGKVNMYMKKLKKRLSKDSEDLKKKLSQYGEDFRKSTEDKVENLRKAVEPYLSNVKDKGQQRLMNLKDAIDEQGKQLRDRFVSVAKDAQAKMKKTASDVKSSVDKLGEQFRKWFNPNVESLRNQLQALAKSLQTKANK
The following text describes a protein:
Function:
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
Sequence:
MSSADDQTTTTTSSELRADIRRLGDLLGETLVRQEGPELLELVEKVRRLTREDGEAAAELLRGTELETAAKLVRAFSTYFHLANVTEQVHRGRELGAKRAAEGGLLARTADRLKDADPEHLRETVRNLNVRPVFTAHPTEAARRSVLNKLRRIAALLDTPVNESDRRRLDTRLAENIDLVWQTDELRVVRPEPADEARNAIYYLDELHLGAVGDVLEDLTAELERAGVKLPDDTRPLTFGTWIGGDRDGNPNVTPQVTWDVLILQHEHGINDALEMIDELRGFLSNSIRYAGATEELLASLQADLERLPEISPRYKRLNAEEPYRLKATCIRQKLENTKQRLAKGTPHEDGRDYLGTAQLIDDLRIVQTSLREHRGGLFADGRLARTIRTLAAFGLQLATMDVREHADAHHHALGQLFDRLGEESWRYADMPREYRTKLLAKELRSRRPLAPSPAPVDAPGEKTLGVFQTVRRALEVFGPEVIESYIISMCQGADDVFAAAVLAREAGLIDLHAGWAKIGIVPLLETTDELKAADTILEDLLADPSYRRLVALRGDVQEVMLGYSDSSKFGGITTSQWEIHRAQRRLRDVAHRYGVRLRLFHGRGGTVGRGGGPTHDAILAQPWGTLEGEIKVTEQGEVISDKYLIPALARENLELTVAATLQASALHTAPRQSDEALARWDAAMDVVSDAAHTAYRHLVEDPDLPTYFLASTPVDQLADLHLGSRPSRRPGSGVSLDGLRAIPWVFGWTQSRQIVPGWYGVGSGLKALREAGLDTVLDEMHQQWHFFRNFISNVEMTLAKTDLRIAQHYVDTLVPDELKHVFDTIKAEHELTVAEVLRVTGESELLDADPVLKQTFTIRDAYLDPISYLQVALLGRQREAAAANEDPDPLLARALLLTVNGVAAGLRNTG
The following text describes a protein:
Function:
Plays an inhibitory role in anti-RNA viral innate immunity by targeting the adapter DDX3X and promoting its 'Lys-48'-linked polyubiquitination. Alternatively, enhances the cGAS-STING pathway activation by promoting 'Lys-63'-linked ubiquitination of STING1, facilitating the STING1-TBK1 complex formation and STING1 activation; (Microbial infection) Plays a positive role in human immunodeficiency virus (HIV-1) replication.
Subcellular Localization:
Cytoplasm.
Sequence:
MWWRDLTRLRLWLKREAIPGEGRKAAKVNAGVGEKGIYTASSRGGPPSARSKAVTVVAEGAASRSWLSMDAPELGPGLVERLEQLATCPLCGGSFEDPVLLACEHSFCRACLARRWGTPPATGTEASPTACPCCGLPCPRRSLRSNVRLAVEVRISRELREKLAEPGARAGRRRGGRIPTMGCLDLPGEDMRKTWRRFEVPTSKSSNSEDDLPEDYPVVKKMLHRLTADLTLDPGTAHRRLLISADRRSVQLAPPGTPAPPDGPKRFDQLPAVLGAQGFGAGRHCWEVETADAASCRDSSGEDADDEESHYAVGAAGESVQRKGCVRLCPAGAVWAVEGRGGRLWALTAPEPTLLGGVEPPPRRIRVDLDWERGRVAFYDGRSLDLLYAFQAPGPLGERIFPLFCTCDPRAPLRIVPAES
The following text describes a protein:
Function:
May be involved in pectin and/or xylans biosynthesis in cell walls.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MNQVRRWQRILILSLLLLSVLAPIVFVSNRLKSITSVDRGEFIEELSDITDKTEDELRLTAIEQDEEGLKEPKRILQDRDFNSVVLSNSSDKSNDTVQSNEGDQKNFLSEVDKGNNHKPKEEQAVSQKTTVSSNAEVKISARDIQLNHKTEFRPPSSKSEKNTRVQLERATDERVKEIRDKIIQAKAYLNLALPGNNSQIVKELRVRTKELERATGDTTKDKYLPKSSPNRLKAMEVALYKVSRAFHNCPAIATKLQAMTYKTEEQARAQKKQAAYLMQLAARTTPKGLHCLSMRLTTEYFTLDHEKRQLLQQSYNDPDLYHYVVFSDNVLASSVVVNSTISSSKEPDKIVFHVVTDSLNYPAISMWFLLNPSGRASIQILNIDEMNVLPLYHAELLMKQNSSDPRIISALNHARFYLPDIFPGLNKIVLFDHDVVVQRDLTRLWSLDMTGKVVGAVETCLEGDPSYRSMDSFINFSDAWVSQKFDPKACTWAFGMNLFDLEEWRRQELTSVYLKYFDLGVKGHLWKAGGLPVGWLTFFGQTFPLEKRWNVGGLGHESGLRASDIEQAAVIHYDGIMKPWLDIGIDKYKRYWNIHVPYHHPHLQRCNIHD
The following text describes a protein:
Function:
Catalyzes the dehydrogenation of (R)-lactate (D-lactate) to pyruvate. Is likely involved in the utilization of D-lactate as a sole source for both carbon and electrons for dissimilatory sulfate reduction. Cannot use L-lactate as substrate, and NAD(+), horse cytochrome c, methylene blue or dimethylnaphthoquinone as acceptors. Active in vitro with artificial electron acceptors such as 2,6-dichlorophenolindophenol (DCPIP); the physiological acceptor is not known, but potential acceptors include cytochromes or quinones.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Note=Extracellular part of the protein faces the S-layer.
Sequence:
MSWIDELSKIVEVFPPSDAYRFDETPPLVAPRAAENFVVVKPSNSEEVSAILKFANEKSIPVFMRGGGTGLSGGAVPTEEGIVLSTEKMTELEVDADNRVAICGAGVTLKQLDDAAFRHGLSFPPHPGAETATVGGMIATNAGGVRALKYGTMRNYVLSLEAVLADGRIINVGGKTIKNSSGYSLLHLLVGSEGTLAVITKATIRLFPQMRDMTVLAIPFPTMEDAMNCVVEVARKMLPMALEFMEKRAVEIGEKVSGERWVSREGEAHLLMVFESFDEAEEAAKIAQSLGAIDVYAATTKKDQDRLLKVRGMIYEGLRKEVIEVLDACVPPAKIAEYWRRSNELAEEYGIELITYGHAGDGNVHQHPLVYEGWEKSYFEFRKSLLSLAVSLGGVISGEHGIGAVKLSELEELFPEQFELMRQIKLLFDPKNILNPGKVVRKL
The following text describes a protein:
Function:
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. Binds the APUM-binding elements (APBEs) in the 3'-UTR mRNA sequence of CLV1, PNH, WUS and FAS2.
Subcellular Localization:
Cytoplasm.
Sequence:
METPRFFYQFDMTTQSVDHNIVLSNVNISNGDKMMAPNSNGNLKGKNSLESELESILLKQQQQQHNRNLVGERERDLNISRSGSAPPTVEGSLNAVGSLFKNSNLAQSSNNNNNNNKNSNGDSSSSEIMTEEQIRSHPAYLAYYYSNVNLNPRLPPPLLSREDWRIAQRIEQGGNSSLFAMQPGFPIQRAENEMINLRKAAARNLSRGTLEPSSGIGVRKKSFADIVHEGLDQPARSSADLSHSTSTETTEALHTGKAPPGFSGVQKVQHPKPCHTNSFTSAIGSSQRRSGTPEPHPFTKSPSPQLSVGHSDGIDITSLSQLHYDDNTQQSWFQIRVSNGNRQGDHQQFMEYCGAENLDTASESADLVKNKDVLRDHNSTFYIDGRANFLRTLSPEFVSQKSNVQHQVNNYQIVDSTGYIPGGYKYNQKLNVALNGNLGVQLNGVSANGRHLRSDSKETTQYLQKTSVDNSSKGRNFVGASHGNTDLKVLGTMYADTSLPQQKQQYPLSFLHNCYSLRDQYHSTHALGSAIILCQENKLANSWYSDNVAEGRVVPSLLDDLKNKPRSLDLLDVLNHVVEFSKDQYGSRFIQKKLETATVEEKMKIFPEILPHAHSLMTDVFGNYVIQKFLEHGTESQRKELARQLIGHVLPLSLQMYGCRVIQKALEVFDVELQTKMVIELDGYVMKCVRDQNGNHVIQKCIEHVPQDRIHLIVASFFGQVVSLSTHPYGCRVIQRVLEHCNDSDTQKIIMDEIMQAVGTLVLDQYGNYVIQHVLQHGKPHERSVIIDKLTGQIVKMSQHKYASNVVEKCLIFATPEERQLLVNEMLGSTQENEPLQAMMKDPFGNYVVQKVLETCDDQSRELILSRIRIHLTALKKYTYGKHIVSRVEKLIATGEKHAALSSNSSRGNLVLRN
The following text describes a protein:
Function:
Catalyzes the NADH-dependent reduction of rubredoxin (Rd). NADPH is a very poor electron donor compared to NADH. Functions as an intermediate component in the electron transfer chain: NADH->NROR->Rd->FprA1/2. Also functions as an intermediate component in the electron transfer chains from NADH to revRbr and Dfx. Therefore, is a key electron carrier in an efficient multienzyme complex that can scavenge O(2) and reactive oxygen species (ROS), and thus plays an important role in the oxidative stress defense system in C.acetobutylicum, an obligate anaerobic bacterium.
Miscellaneous:
MISCELLANEOUS: The disulfide bonds are not involved in the electron transfer from NADH to rubredoxin catalyzed by NROR.
Domain:
Is composed of three domains: an FAD-binding domain (residues 2-107 and 223-297), an NADH-binding domain (residues 108-222), and a C-terminal domain (residues 298-379).
Sequence:
MKSTKILILGAGPAGFSAAKAALGKCDDITMINSEKYLPYYRPRLNEIIAKNKSIDDILIKKNDWYEKNNIKVITSEFATSIDPNNKLVTLKSGEKIKYEKLIIASGSIANKIKVPHADEIFSLYSYDDALKIKDECKNKGKAFIIGGGILGIELAQAIIDSGTPASIGIILEYPLERQLDRDGGLFLKDKLDRLGIKIYTNSNFEEMGDLIRSSCVITAVGVKPNLDFIKDTEIASKRGILVNDHMETSIKDIYACGDVAEFYGKNPGLINIANKQGEVAGLNACGEDASYSEIIPSPILKVSGISIISCGDIENNKPSKVFRSTQEDKYIVCMLKENKIDAAAVIGDVSLGTKLKKAIDSSKSFDNISSLDAILNNL
The following text describes a protein:
Function:
GTPase involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export.
Sequence:
MVLNSLDKMIQLQKNTANIRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYMDSREDEQIRGITMKSSAISLHYAKDDEEYLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVINKIDRLIVELKFTPQEAYSHLKNILEQINALTGTLFTSKVLEERAERVTESQVNPHSEQGEQVYDWSTGLEDTDDSHLYFSPDQGNVVFTSAIDGWGFGIEHFAKIYSQKTGIRKEVLLKTLWGDYYINMKAKKIMKVDQAKGKKPLFVQLILGNIWSLYDAVLKKDKEKIDKIVTSLGLKIGAREARHSDPKVQINAICSQWLPISQAVLAMVCQKLPSPLDITAERVEKLMCAGSQTFDSLPPETQALKAAFMKCGSEDTAPVIIFVSKMFAVDAKALPQNKPRPLTPEEIAERRERARRRHAEKLAAAQGQAPVEPTQDGSALEASPKEEEPKGDEQQVLQEGNDQESFIAFARVFSGVARRGKKIFVLGPKYSPLEFLQRVPLGFSAPLDGLPPVPHMACCTLENLYLLMGRELEDLEEVPPGNVLGIGGLQDFVLKSATLCTLPSCPPFIPLNFEATPIVRVAVEPKHPSEMPQLVKGMKLLNQADPCVQILIQETGEHVLVTAGEVHLQRCLDDLKERFAKIQISVSEPIIPFRETITKPPKVDMVNEEIGKQQKVAVIHQTKEDQSKIPEGIQVDSDGLVTITTPNKLATLCVRAMPLPEEVTQILEENSDLIRSMEQLTSSLNEGKNTQVIHQKTQEKIGEFKGRLEQHLTGRKWRNTVDQIWSFGPRKCGPNILVNKSEDFQNSVWTGPDGKASQEANRYRDLGNSIVSGFQLATLSGPMCEEPLMGVCFVLEKWDLSKFEEQTASDKQNQKQSDLVDAGQGEGETSSAGDENQEVHNGCSEPFEKRPSQKGESSLTDCYGPFSGQLIATMKEACRYALQVKPQRLMAAMYTCDIMATSDVLGRVYAVLSKREGRVLQEEMKEGTDMFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEIIPSDPFWVPTTEEEYLHFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSKNK