lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the rate-limiting reaction in the mitochondrial fatty acid synthesis (FAS) type II pathway. Responsible for the production of the mitochondrial malonyl-CoA, used for the biosynthesis of the cofactor lipoic acid. This protein carries three functions: biotin carboxyl carrier protein, biotin carboxylase, and carboxyltransferase.
Miscellaneous:
MISCELLANEOUS: Present with 396 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
KGKTITHGQSWGARRIHSHFYITIFTITCIRIGQYKLALYLDPYRFYNITGSQIVRLKGQRPEYRKRIFAHSYRHSSRIGLNFPSRRRYSNYVDRGNIHKHTRLPPQFIGLNTVESAQPSILRDFVDLRGGHTVISKILIANNGIAAVKEMRSIRKWAYETFNDEKIIQFVVMATPDDLHANSEYIRMADQYVQVPGGTNNNNYANIDLILDVAEQTDVDAVWAGWGHASENPCLPELLASSQRKILFIGPPGRAMRSLGDKISSTIVAQSAKIPCIPWSGSHIDTIHIDNKTNFVSVPDDVYVRGCCSSPEDALEKAKLIGFPVMIKASEGGGGKGIRRVDNEDDFIALYRQAVNETPGSPMFVMKVVTDARHLEVQLLADQYGTNITLFGRDCSIQRRHQKIIEEAPVTITKPETFQRMERAAIRLGELVGYVSAGTVEYLYSPKDDKFYFLELNPRLQVEHPTTEMISGVNLPATQLQIAMGIPMHMISDIRKLYGLDPTGTSYIDFKNLKRPSPKGHCISCRITSEDPNEGFKPSTGKIHELNFRSSSNVWGYFSVGNNGAIHSFSDSQFGHIFAVGNDRQDAKQNMVLALKDFSIRGEFKTPIEYLIELLETRDFESNNISTGWLDDLILKNLSSDSKLDPTLAIICGAAMKAYVFTEKVRNKYLELLRRGQVPPKDFLKTKFPVDFIFDNNRYLFNVAQSSEEQFILSINKSQCEVNVQKLSSDCLLISVDGKCHTVYWKDDIRGTRLSIDSNTIFLEAELNPTQVISPTPGKLVKYLVRSGDHVFAGQQYAEIEIMKMQMPLVAKSDGVIELLRQPGSIIEAGDVIAKLTLDSPSKANESSLYRGELPVLGPPLIEGSRPNHKLRVLINRLENILNGYHENSGIETTLKELIKILRDGRLPYSEWDSQISTVRNRLPRQLNEGLGNLVKKSVSFPAKELHKLMKRYLEENTNDHVVYVALQPLLKISERYSEGLANHECEIFLKLIKKYYAVEKIFENHDIHEERNLLNLRRKDLTNLKKILCISLSHANVVAKNKLVTAILHEYEPLCQDSSKMSLKFRAVIHDLASLESKWAKEVAVKARSVLLRGIFPPIKKRKEHIKTLLQLHIKDTGAENIHSRNIYSCMRDFGNLIHSNLIQLQDLFFFFGHQDTALSSIASEIYARYAYGNYQLKSIKIHKGAPDLLMSWQFSSLRNYLVNSDGESDEFTKLSKPPSTSGKSSANSFGLLVNMRALESLEKTLDEVYEQIHIPEERLSSGENSLIVNILSPIRYRSENDLIKTLKIKLHENERGLSKLKVNRITFAFIAANAPAVKFYSFDGTTYDEISQIRNMDPSYEAPLELGKMSNYKIRSLPTYDSSIRIFEGISKFTPLDKRFFVRKIINSFMYNDQKTTEENLKAEINAQVVYMLEHLGAVDISNSDLNHIFLSFNTVLNIPVHRLEEIVSTILKTHETRLFQERITDVEICISVECLETKKPAPLRLLISNKSGYVVKIETYYEKIGKNGNLILEPCSEQSHYSQKSLSLPYSVKDWLQPKRYKAQFMGTTYVYDFPGLFHQAAIQQWKRYFPKHKLNDSFFSWVELIEQNGNLIKVNREPGLNNIGMVAFEIMVQTPEYPEGRNMIVISNDITYNIGSFGPREDLFFDRVTNYARERGIPRIYLAANSGAKLGIAEELIPLFRVAWNDPSDPTKGFQYLYLAPKDMQLLKDSGKGNSVVVEHKMVYGEERYIIKAIVGFEEGLGVECLQGSGLIAGATSKAYRDIFTITAVTCRSVGIGSYLVRLGQRTIQVEDKPIILTGASAINKVLGTDIYTSNLQIGGTQIMYKNGIAHLTASNDMKAIEKIMTWLSYVPAKRDMSPPLLETMDRWDRDVDFKPAKQVPYEARWLIEGKWDSNNNFQSGLFDKDSFFETLSGWAKGVIVGRARLGGIPVGVIAVETKTIEEIIPADPANLDSSEFSVKEAGQVWYPNSAFKTAQTINDFNYGEQLPLIILANWRGFSGGQRDMYNEVLKYGSFIVDALVDYKQPILIYIPPFGELRGGSWVVIDPTINPEQMEMYADVESRGGVLEPDGVVSIKYRKEKMIETMIRLDSTYGHLRRTLTEKKLSLEKQNDLTKRLKIRERQLIPIYNQISIQFADLHDRSTRMLVKGVIRNELEWKKSRRFLYWRLRRRLNEGQVIKRLQKKTCDNKTKMKYDDLLKIVQSWYNDLDVNDDRAVVEFIERNSKKIDKNIEEFEISLLIDELKKKFEDRRGNIVLEELTRLVDSKRKR
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
QPHCDPYSWGDLFPSCHPLLEHHHSPINFDPHMPRSDSLGPLHLEGFDVTQPGHWTLTNDGHSVLLQVGSGMAVSGGGLLDEYHTIQLHFHWGGPATNGSEHTVDGRRYPMEMHIVSVKSVHPNMSAALEDPTGLAVLGFFIDVVYADNVHFGHISQMLSSVAYKGQTAKVKPFPLMGLLPRHNMSQYYRYYGSLTTPPCSQAVVWTLYQVPIYISWSQLAQFTSQIFATEEDAEQVTPLQNNFRHIHPTFGRSVTASRDAILPKGAAGRPIRAAVLLLPITFLGSFGL
The following text describes a protein:
Function:
Recombinant, non-modified protein stimulates secretion of cytokines (TNF-alpha, IL-6 and IL-12p40) by mouse macrophage cell lines in a TLR2-dependent fashion, which leads to increased host innate immunity responses against the bacterium. Serves as a strong human and mouse antigen T cell antigen during M.tuberculosis infection, inducing strong IFN-gamma expression.
Subcellular Localization:
Cell membrane; Lipid-anchor. Secreted, cell wall. Secreted.
Sequence:
MINVQAKPAAAASLAAIAIAFLAGCSSTKPVSQDTSPKPATSPAAPVTTAAMADPAADLIGRGCAQYAAQNPTGPGSVAGMAQDPVATAASNNPMLSTLTSALSGKLNPDVNLVDTLNGGEYTVFAPTNAAFDKLPAATIDQLKTDAKLLSSILTYHVIAGQASPSRIDGTHQTLQGADLTVIGARDDLMVNNAGLVCGGVHTANATVYMIDTVLMPPAQ
The following text describes a protein:
Function:
Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.
Sequence:
MKTIRTFLAIPLPSDLARTASRWMAETKSPGDGIKWVPDENLHLTLKFLGEVDNVETPAVCNTLQAACEDIEPFALVLEGASGIPDLERPRVLTVAVDDATSTLTNLVADLEKRFAAMGYKPEPRDYRPHLTVGRTRSGTRRANSDVINRWRKFEDDEIGEFNVREIHVVGSFLEKHGPTYNVLGRVQL
The following text describes a protein:
Function:
Accessory subunit of the vacuolar transporter chaperone (VTC) complex. The VTC complex acts as a vacuolar polyphosphate polymerase that catalyzes the synthesis of inorganic polyphosphate (polyP) via transfer of phosphate from ATP to a growing polyP chain, releasing ADP. VTC exposes its catalytic domain VTC4 to the cytosol, where the growing polyP chain winds through a tunnel-shaped pocket, integrating cytoplasmic polymer synthesis with polyP membrane translocation. The VTC complex carries 9 vacuolar transmembrane domains, which are likely to constitute the translocation channel into the organelle lumen. PolyP synthesis is tightly coupled to its transport into the vacuole lumen, in order to avoid otherwise toxic intermediates in the cytosol, and it depends on the proton gradient across the membrane, formed by V-ATPase. Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5-InsP7); these are important intracellular signaling molecules. Inositol polyphosphate binding promotes vacuolar polyphosphate synthesis. The VTC complex also plays a role in vacuolar membrane fusion. Required for SEC18/NSF activity in SNARE priming, membrane binding of LMA1 and V(0) trans-complex formation.
Miscellaneous:
MISCELLANEOUS: Present with 2915 molecules/cell in log phase SD medium.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein. Cytoplasm, cell cortex. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein.
Domain:
The SPX domain has very high affinity for inositol polyphosphates, such as myo-inositol hexakisphosphate and 5-diphospho-myo-inositol pentakisphosphate (5-InsP7), and moderate affinity for inorganic pyrophosphate. Its affinity for inorganic phosphate is 2 to 3 orders of magnitude lower (Probable). SPX domains may integrate inositol pyrophosphates (PP-InsP)-dependent signaling to adapt cytosolic phosphate concentrations to different metabolic situations (Probable).
Sequence:
MLFGVKLANEVYPPWKGSYINYEGLKKFLKEDSVKDGSNDKKARWDDSDESKFVEELDKELEKVYGFQLKKYNNLMERLSHLEKQTDTEAAIKALDADAFQRVLEELLSESTELDNFKRLNFTGFAKIVKKHDKLYPKYPSVKSLLEVRLKELPSHSEEYSPLLYRISFLYNILRSNFNTASEPLASASKFSSIVSNDIDMNFRSFKFWVHNDNLMEVKTRILRHLPVLVYANVPSENDDLVNRFESDISNNDEIVGSSSSTSSVEHGLGARSFDPLINTLYFDNEHFELYNDKLLKLNSAPTLRLRWTGQLSDKPDIFLEKKTLIEDEATGKSEFDLTKLQLKQKFINGFIFEGDKKFKEQTLKKLKESGTAGRDLERLEEDFSEIQNFIIKNELQPVFRTVYTRTAFQIPGDDKIRVTIDSNIVFIKEDSFDRERPIRDPNTWHRTDIDANVANPLKFLRGGEYAKFPYSVMEIKVKSSLDSSMSASSMISNVKLPKKHGQWLNDLTNSHLVKEIPKFSIFVQGVASLYGDDEKLDILPFWLPDLETDIRQDPKQAYEEEKKKLLKQKEIQKKIDGMRRLSNLKEPQHQAAVPVSQEENERITSQGDLEADGSSDEETEQEPHSKRSKKVRRRKPKATFLRILAGRDPKLMGVDSEEEEIELPPGVKKPLNLLKNAGPVNVEAKVWLANERTFNRWLSVTSLLSVLTFSIYNSVKKAEYPTLANYMAYVYFGLTIFCALWSYSIYMKRVDIIQQRSGQHLDAPLGPVLVSIVLFVTLVVNFVMAFRNAAKSRQELQIQNLEVPERIPEVLRPLQNYLFKLMGPSSD
The following text describes a protein:
Function:
Acts as a catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover (By similarity). Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MFYPHHQSQQSTTTNPSKHHDSQDVRLPGTSSWSRHPSHPSFTPSLPMPSPSGYPPLGSGYPPGGHHHPNVNVHSGIHGPHPSFGSGMGGNGGMGHGQGFGMGMFQNGVQTSPPRGEPVPMTSHWQTQMMRAEASRSASSPHHRARAAAISSRATNKPSAVPIVDPNNRPSSSYGTNGLHRKNASSVFNGEPTGTPPLSDPSLTPAQNPAEPATPAPVAGQTESKDEEKPNEPWTGLDLGGIRLKRLSTALFSFTHVTSLYINHNALTSIPSAISSLRQLTLLDATGNELSTIPSEIGVLSKLKDLLLFDNNLTTLPFELGTLYQLDCLGIDGNPMNADYRKKLVEDGTRGLITYLRDHAPPPPPPPERQWIDLETDVDTPTSGKQESFSVLTYNILCASFAPATTYSYTPSWALDWDYRKRLLLEEIVTASADVVCLQEIDCKQYADYFYPMLKKEGYEGQHYPRSRAKTMSVDEQKLVDGCATFWKEEKFRLVETQVIEFNQLALQKTDMRTEDMFNRVMSRDNIAVVAALEFRASGGRLLVANSHIYWDHRYRDVKLVQIGMLMEELEKIVEQFSRYPVKLDTDPEYNNGKPPKYERSEKGRDIPLIMCVDLNSFSGSAVYDYLSSGSIPGDHEDFMSHLYGRYTASGLKHHLGLRSACAGIGEMRMTNFTPTFAAAIDYVFYTPRTMKVTSVLGDVDKAYLDKTVGFPNAHFPSDHIPVFTQFRIKGHLDPLPLNGDPYH
The following text describes a protein:
Function:
Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MALPAIQGTGFQFRRILGYFPQDISLAFAYGSGVFRQSGTPQNDAGNKMLDFVFAVDDPVTWHTMNIIQNRSHYSFLKFLGPKHIAAVQNNYGAGIYYNTLVPCDGRVSMWHLGTAPPLCSELACIKYGLVQGVAHETLAGSDLLALEGRCYSAGTAVFTIFRVSCHSESERSFPCHMTELWAILMFQVKILTQRDEGRLHTALSTNLKSALTAAFLMLPESFSEEELYLQIAGLSYAGDFRMIIGEDKDKVLNIVKPNVPHFQKLYAPILQDCPLAVYKAKQGRVEVDKSPEGQYQQLMALPKKLQQNMAALVDPPGKNRDVEEILLQVAQDPDCGNVVQQALYGIVRSSSVSQSAKGILTAGVRKTAQYSSKKLYKMLRSLRKGKL
The following text describes a protein:
Function:
Catalyzes the non-oxidative deamination of L-phenylalanine to form trans-cinnamic acid, the first step in the phenylpropanoid pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MKTLSQAQSKTSSQQFSFTGNSSANVIIGNQKLTINDVARVARNGTLVSLTNNTDILQGIQASCDYINNAVESGEPIYGVTSGFGGMANVAISREQASELQTNLVWFLKTGAGNKLPLADVRAAMLLRANSHMRGASGIRLELIKRMEIFLNAGVTPYVYEFGSIGASGDLVPLSYITGSLIGLDPSFKVDFNGKEMDAPTALRQLNLSPLTLLPKEGLAMMNGTSVMTGIAANCVYDTQILTAIAMGVHALDIQALNGTNQSFHPFIHNSKPHPGQLWAADQMISLLANSQLVRDELDGKHDYRDHELIQDRYSLRCLPQYLGPIVDGISQIAKQIEIEINSVTDNPLIDVDNQASYHGGNFLGQYVGMGMDHLRYYIGLLAKHLDVQIALLASPEFSNGLPPSLLGNRERKVNMGLKGLQICGNSIMPLLTFYGNSIADRFPTHAEQFNQNINSQGYTSATLARRSVDIFQNYVAIALMFGVQAVDLRTYKKTGHYDARACLSPATERLYSAVRHVVGQKPTSDRPYIWNDNEQGLDEHIARISADIAAGGVIVQAVQDILPCLH
The following text describes a protein:
Function:
Plays an essential role in cytoplasmic secondary envelopment during viral egress. Interacts with the capsid via the large tegument protein/LTP and participates in its transport to the host trans-Golgi network (TGN) where secondary envelopment occurs. Modulates tegumentation and capsid accumulation at the viral assembly complex.
Subcellular Localization:
Virion tegument. Host cytoplasm. Host nucleus. Host Golgi apparatus, host trans-Golgi network.
Sequence:
MMARRTVDFKKLIEQLRARATDKAEALNTVSQLEIGAVDAQDVTASAVRAFVGALPSSGYHFGFVRQNVVFYLLSHATVQTARDPLYAAEQLHEQLDRFLRHQHDGGGDEDRLPFYHNGATLTAFQKLLQTLREIQTVIAEQSGGTAAAADLIASNNASTERRGKKGGSSSGGQQPLVRRVITQLETAATEARPYVNCRAVAELLDLTYQRLIYWACTLMPYVLFRRDTDTELDTVLLMHFFYTHYRSVNGDLAVEFQNYVKNSVRHMSSFVSSDIDGDQKPGAEHMRDVSYKLFVGNLQARDASGLMFPIISTRISTVNLYLSPERMFFHPGLISRLLSEEVSPRANLDAYARVCDRVLEDHLHTPRRVQRLLDLTQMVMRLVELGFNHDTCAAYAQMALIQPASQKSSLFVSEIREKLIQIIYNFYTFFMCLYVYSPTFLFDHRRRLILEQHRSTLIGSKEELQHVWSNVTLNVNTHFAVQYTEEDFEAHTKGATEAEREYLYRDLHSKWGVHLFTLRPSRGAAGAASPLPPLDGVTRSDILRECALVNLNEGRVNYASLLAFSHHPEFPSIFAQLVVVTEFSEIFGIPQGLFQAVGSPRLFALIQLCRVLLPEQVTLYQNLVSIYNLTTFVKHIDAAVFKTVRDCVFDIATTLEHLSGVPVTPNVDLLAELMARSVAHNLYTTVNPLIEDVMRSSAGSLRNYLRHTRLCFGLARGRARLSEDGVTVYVEVQGQYGLRVPTTRFVEQLRELVRRDRLLAENLRGLNERLLSVRVRVRQISSDTEEVSRHAKGHRTVAQMSKALKKTASKIKMLETRVTLALEQAQRSNGAVVTAVQRALAVFDVLSRENLERRGAQLCLTEATSLLHRHRALAPMTWPAGTGVAAAAEADGALREFLEAPWESAPQPPRLRMTPDTDHEESTAGATSVPEVLGARYEPAHLAASDLLNWYIVPVSQAQQDILSSIDPPAGSTSVSLPPASP
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MASPAALRPSMGAIMQTCRSAATAPKVAVAVPVRALSTSAALLKRHKYPTARVTRDNSKQRGESALRKSGTRWKLSVSDEPLPEPVPREELPPIQVDENHGLWDFFYDRETVAMAPLEHTKHGRAWTVSELRKKSWDDLHRLWWVCVKERNRIATANWERTKSELGFGLAEANERDRNVKQTMRGIKHVLTERFYAWEDAVKLAEQDPEIDLSNPENPYTPSTFLEAEETAEGAEASETQSTTTEIDPTTIPSSKSQAEAPRV
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MTAQKLPKLKYLRVKNLQTAEAPQAVQLLSRLLACWSSNGVNSEACKEIEQEFKMAACKSVKPVKQQDSINFHAKRLYPKMVPQGKNRR
The following text describes a protein:
Function:
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
Subcellular Localization:
Cytoplasm.
Sequence:
MLNSFDAAYHSLCEEVLEIGNTRNDRTNTGTISKFGHQLRFDLSKGFPLLTTKKVSFKLVATELLWFIKGDTNIQYLLKYNNNIWNEWAFENYIKSDEYKGPDMTDFGHRALSDPEFNEQYKEQMKQFKQRILEDDTFAKQFGDLGNVYGKQWRDWVDKDGNHFDQLKTVIEQIKHNPDSRRHIVSAWNPTEIDTMALPPCHTMFQFYVQDGKLSCQLYQRSADIFLGVPFNIASYALLTHLIAKECGLEVGEFVHTFGDAHIYSNHIDAIQTQLARESFNPPTLKINSDKSIFDINYEDLEIVDYESHPAIKAPIAV
The following text describes a protein:
Function:
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Subcellular Localization:
Cytoplasm.
Sequence:
MAGPVGVAATLYRISATPVRYAVMDSKKMKESDRAETLEAMCAELSDAGVEGFVGTTVRDGACCLVRYQRRKPLQAVAAALVDVSVINERNILNATLEGMSAVCEAVVRSYNAVSGLGTLTPLTCAILIDGNRVPWTFLSGEERQRVCVQAVRKVEARKRIGVEYPALDGFSCTTVVKGDATLLSIAAASIVAKVARDAYAVSVMHPAFPQYGFDHHKGYCTAAHKAELARWGPSRFHRLDYAPVKGTLGGQRGDAERTPASLEGPVM
The following text describes a protein:
Function:
Component of the helicase/primase complex. Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis. The primase synthesizes short RNA primers on the lagging strand that the polymerase elongates using dNTPs. Possesses helicase-like motifs and therefore may act as the helicase subunit of the complex.
Subcellular Localization:
Host nucleus.
Sequence:
MAAAGGERQLDGQKPGPPHLQQPGDRPAVPGRAEAFLNFTSMHGVQPILKRIRELSQQQLDGAQVPHLQWFRDVAALESPAGLPLREFPFAVYLITGNAGSGKSTCVQTINEVLDCVVTGATRIAAQNMYAKLSGAFLSRPINTIFHEFGFRGNHVQAQLGQYPYTLTSNPASLEDLQRRDLTYYWEVILDLTKRALAASGGEELRNEFRALAALERTLGLAEGALTRLAPATHGALPAFTRSNVIVIDEAGLLGRHLLTAVVYCWWMINALYHTPQYAARLRPVLVCVGSPTQTASLESTFEHQKLRCSVRQSENVLTYLICNRTLREYARLSYSWAIFINNKRCVEHEFGNLMKVLEYGLPITEEHMQFVDRFVVPENYITNPANLPGWTRLFSSHKEVSAYMAKLHAYLKVTREGEFVVFTLPVLTFVSVKEFDEYRRLTHQPGLTIEKWLTANASRITNYSQSQDQDAGHMRCEVHSKQQLVVARNDVTYVLNSQIAVTARLRKLVFGFSGTFRAFEAVLRDDSFVKTQGETSVEFAYRFLSRLIFSGLISFYNFLQRPGLDATQRTLAYARMGELTAEILSLRPKSSGVPTQASVMADAGAPGERAFDFKQLGPRDGGPDDFPDDDLDVIFAGLDEQQLDVFYCHYTPGEPETTAAVHTQFALLKRAFLGRFRILQELFGEAFEVAPFSTYVDNVIFRGCEMLTGSPRGGLMSVALQTDNYTLMGYTYARVFAFADELRRRHATANVAELLEEAPLPYVVLRDQHGFMSVVNTNISEFVESIDSTELAMAINADYGISSKLAMTITRSQGLSLDKVAICFTPGNLRLNSAYVAMSRTTSSEFLRMNLNPLRERHERDDVISEHILSALRDPNVVIVY
The following text describes a protein:
Function:
Required for nucleus structure organization (e.g. size and shape).
Subcellular Localization:
Nucleus inner membrane.
Sequence:
MDSVSGYAAGAGQPRVGGKIVRPRRTAVVRTPCERPVQRSRDPPQQNPSWISRLVYKPASVIASGAGKFISSVVFSDSSSSSEEDEDSSSDIDGDEDVEKNNPDFTEEDLLSAQQPSIQRLSSKRVIEQLLLQETFAREEGDRLIDIIKARVVDHPSVPSAIETSHDDYGLTSDVNVGEMSNTAVMEARKWLEEKKSGSSSKYKATEDGAGSPVDVAKSYMRARLPWGSPAANNLDFRSPSSARVQGTPLPYSAGNFSSSKLKRKSGSNQSWNIQDEIRKVRAKATEEMLKSPSSVASLEPKYSPYVLATDMLKGNASSLNADGAVRNEQSRALPNSAIPTSEHNQTTEANQAVKETGVLHTRSRGVGLEETFISTQGVKPSEDTNTAPQSGTAVDDFNDQDGDFIQPTSTIGNTTNAVLALGATLDPTGNSCIPKDVFETSKEADEIGASRHTSNGFPSSSPSGYGRSTKTHTTRRNQGFSAYS
The following text describes a protein:
Function:
Required, but not essential, for D1 (psbA) precursor processing and thus correct photosystem II assembly (PSII).
Subcellular Localization:
Plastid, chloroplast thylakoid lumen. Note=Associated with PSII on the lumenal side of the thylakoid membrane.
Sequence:
MGFLVAVMNFSPTLVHHHMKSKPQCQNEKLRQGQTSSLFDRRGFLKCVVGASSFMATIEFSGLQAQASEEKLDEGEGVVGAFKTLFDPNERTKSGKELPKAYLKSAREVVKTMRESLKENPKDNAKFRRSADAAKESIRDYLSNWRGQKTVAGEESYVELENVIRALAKFYSKAGPSAPLPDEVKTEILDDLNKAEEFL
The following text describes a protein:
Function:
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
Sequence:
MDDSDIKRLGEILITAEEEEEWLNTPDEHDHTETSTHQSYVTILKEGDIRSRMKEEIQRVSNTYSISEDDATLLLAHFRWDDIELHKKWSDNAKSVRESVGIFELERPLDLPSDDKNFCCGICFKLLSLERSASVSCGHRVCKFCWRSHINKSINKIADVDWYGTLKCPYDICRASVGGDMIEKFACEEEKTKYYRYLFRSYVEGSKVIKCCPAKGRSCDVHLTPGSGNFDVLCLCLLSFCWNCSKDVHSPMDCESAAKWLRMNSSDYQDPNWVRQNTVPCPRCNLRIRENQDCSLKMRCFPPCNYDFCWRCRGQWTEHGLDLYTCTHDEVSYEEYCFGNMAEYAAGRYKDCHEKWMSNESTVMKTKAKLQQLHTDVIPDLSNKQLATVHQLEFVAEAWSQIMECRRVLKWTYAYEYYLGEDQVEKQAFLKLKQDNAEIPLEKLHYHAENQLNMLLDSDGPSENFNKFRSDLTDSTRITRNHYELLLRDLEDGLSNVVGASTSQRAHNEDDASGSSSIHDD
The following text describes a protein:
Function:
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MAAILRYQLELFLLAVSFFSRIPVPVSLPYSSERMNQAGRYFALVGLLLGAICALVYSLATQLFSTNISVFLTMVLSLLLTGAFHEDGLADMADGVGGGMTAERRLEIMKDSRIGTYGSSALIMVLLGKYLLLTELADLTSLVPVWLLAYTLSRAVAASLIRNTPYVSDTDSSKSKPLAQQLSGTDVAVLSLTALATLLYFSWQFIGVMIAASLIFRQIFRQWLIRRLGGFTGDCLGAAQQLMEILIYLILLAFLQHEVMI
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence:
MAAERVDSKSTQSNHARIIDQVMSSDINLGSAIGAAYENGIDAKALLDQLNARASRIDEDLKRICNRNYQGFVESVQELLSVGEHADDLKLAARECSEGLQDAGEHLRQHNERLLAMRRQHRNVLAGLEALHVCRPAIVLYNQAQQQLREGRAYAALKTLQELEAEQLPRLTSYKFVETIRTEIPALRLQVKRDSMTSLRDFLASLRQSCEPLGAQAMTASQSGSNSGTPRRATQQSIEGTELDFSPLYRCAHICKVLDVMEECAEYYREERRKQLDLVLNPTTSLTSETTFRAYFHAVAGCFIAEHTVLATTDGLISRQWLDSLWQTALTQLSQVTQAQLAQCTTASMIRQVKDMIVTFNRTMLAHEYSVSRLTDVLLQVRSRYQAVLVTISTEAFKAILAEDNYNPLRLDNADQYRELLETYPFEDGATVGATVFPRQLLFSNAVPRLYAEVRHYIDLSHQFLENVGLSSTEVDELLRQSTNHLFSKVLSSILMKLVRSAGLNVQQLTQISLNTTQLELACESLELYISQLTRSIGNDVHGTRLHGADTLKDPRSAAEDGIFACLQGRIDQFLELAEFDWAPSAPKTTPSPHMFELLAYLTTTFAALRHMPTEVARAAYFNTCKYIGQRLISQVEDPEIKKINLNGIKSFEVDVATCEEYADTCPVIEAGDQLLKGAFVQLRELVDVFLRNDWDKFCDPLMRRKYYPHLKTATAITWLEKFEDKAQSSIFGRRSEKKSREVEAVLRQLKAQ
The following text describes a protein:
Function:
Part of the ABC transporter complex CntABCDF (Opp1) involved in the uptake of metal in complex with the metallophore staphylopine (StP). Involved in the import of divalent metals ions such as nickel, cobalt and zinc. Probably responsible for the translocation of the substrate across the membrane. Plays a major role in nickel/cobalt import in zinc-depleted conditions. Contributes to virulence. Required for full urease activity in vitro.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MFKFILKRIALMFPLMIVVSFMTFLLTYITNENPAVTILHAQGTPNVTPELIAETNEKYGFNDPLLIQYKNWLLEAMQFNFGTSYITGDPVAERIGPAFMNTLKLTIISSVMVMITSIILGVVSALKRGKFTDRAIRSVAFFLTALPSYWIASILIIYVSVKLNILPTSGLTGPESYILPVIVITIAYAGIYFRNVRRSMVEQLNEDYVLYLRASGVKSITLMLHVLRNALQVAVSIFCMSIPMIMGGLVVIEYIFAWPGLGQLSLKAILEHDFPVIQAYVLIVAVLFIVFNTLADIINALLNPRLREGAR
The following text describes a protein:
Function:
Represents a citrate:acetyl-ACP transferase.
Subcellular Localization:
Cytoplasm.
Sequence:
MTQKIEQSQRQERVAAWNRRAECDLAAFQNSPKQTYQAEKARDRKLCANLEEAIRRSGLQDGMTVSFHHAFRGGDLTVNMVMDVIAKMGFKNLTLASSSLSDCHAPLVEHIRQGVVTRIYTSGLRGPLAEEISRGLLAEPVQIHSHGGRVHLVQSGELNIDVAFLGVPSCDEFGNANGYTGKACCGSLGYAIVDADNAKQVVMLTEELLPYPHNPASIEQDQVDLIVKVDRVGDAAKIGAGATRMTTNPRELLIARSAADVIVNSGYFKEGFSMQTGTGGASLAVTRFLEDKMRSRDIRADFALGGITATMVDLHEKGLIRKLLDVQSFDSHAAQSLARNPNHIEISANQYANWGSKGASVDRLDVVVLSALEIDTQFNVNVLTGSDGVLRGASGGHCDTAIASALSIIVAPLVRGRIPTLVDNVLTCITPGSSVDILVTDHGIAVNPARPELAERLQEAGIKVVSIEWLRERARLLTGEPQPIEFTDRVVAVVRYRDGSVIDVVHQVKE
The following text describes a protein:
Function:
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Regulates the synthesis of PtdIns(3,5)P2 by positive activation of FAB1 and by controlling FIG4 localization (By similarity).
Subcellular Localization:
Cytoplasm. Vacuole membrane; Peripheral membrane protein.
Sequence:
MDNLLVRGLTHKLYDKRKATAYELERVVKGYLENDETEKIRAVISQLANDFVYSPARGPNATFGGLIGLAAVAIALGPKIDSYMESILLPVLYCFNDSDSKIRYYACESMYNIGKVAKGEVFRYFNLIFDVLCKLFADTEITVKNGAELLDRLIKDIVMQQAATYMSSAEDIKNFKEGPVSSSIQDVPVMSTEQPRMHTFSLSELVPLLSERLYVINPNTRMFLVSWIRLLDSIPDLEFISYLPFLLDGLMNYLSDPNESIRIVTSNCLYDFLREIQKIAKVKYHILQRDEESEPDFFDSMVRRNMSDAELKEISDYVESSLRDGSFILEAHIQIDYKRILEIIIDHLGSSVPLIQEKALKWLFEFIYIAPKDVLLQIPKVLENLLPLMSNDENMRQSAKDLSQNLVILVSKIMDIEFSGSETNNKDNSLSVDFRSLIEVLQKLLSNDNEETRLCALEWVLLLQRRTGGKLINMHDPIFQTLLLQLSDPSDLVVSRTLELLAHIAISHKSVNLVPFLKSLLQMFAEDRKFLNSRGNLIIRQLCNYIEGERVYTSFAGILETEENLELASIMVEVLNNNLFTAPELYDLRKKLKQSAPKLQNIFTTLYTAWCHNSIAVFSLCLLSQNYEHAANLLSVFAEIEFNIDMLIQLDKLVQLIESPVFTYMRLQLLEPEKYPYLHKALYGILMLLPQSSAFRTLRDRLQCSSTPRTNTILANERLPRSRRDDPYWTDLLERLKAVQLSHQNNYREPIRATRLALAGALPSTPTATTISTTTSASGITTTASNSRDSFITRLPPTAALSTGARKKPKQ
The following text describes a protein:
Function:
Postsynaptic protein that regulates circuit dynamics in the central nervous system by modulating the temporal dynamics of interneuron recruitment. Specifically present in excitatory synapses onto oriens-lacunosum molecular (OLM) interneurons and acts as a regulator of presynaptic release probability to direct the formation of highly facilitating pyramidal-OLM synapses (By similarity). Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.
Subcellular Localization:
Membrane; Single-pass type I membrane protein. Cell projection, dendrite. Note=Localizes to excitatory synapses onto somatostatin (Sst)-containing oriens-lacunosum moleculare (O-LM) interneurons.
Sequence:
MAGRGWGALWVCVAAATLLHAGGLARADCWLIEGDKGFVWLAICSQNQPPYEAIPQQINSTIVDLRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLGKLEYLYLQANLIEVVMASSFWECPNIVNIDLSMNRIQQLNSGTFAGLAKLSVCELYSNPFYCSCELLGFLRWLAAFTNATQTYDRMQCESPPVYSGYYLLGQGRRGHRSILSKLQSVCTEDSYAAEVVGPPRPASGRSQPGRSPPPPPPPEPSDMPCADDECFSGDGTTPLVALPTLATQAEARPLIKVKQLTQNSATITVQLPSPFHRMYTLEHFNNSKASTVSRLTKAQEEIRLTNLFTLTNYTYCVVSTSAGLRHNHTCLTICLPRLPSPPGPVPSPSTATHYIMTILGCLFGMVLVLGAVYYCLRRRRRQEEKHKKAASAAAAGSLKKTIIELKYGPELEAPGLAPLSQGPLLGPEAVTRIPYLPAAGEVEQYKLVESADTPKASKGSYMEVRTGDPPERRDCELGRPGPDSQSSVAEISTIAKEVDKVNQIINNCIDALKSESTSFQGVKSGPVSVAEPPLVLLSEPLAAKHGFLAPGYKDAFGHSLQRHHSVEAAGPPRASTSSSGSVRSPRAFRAEAVGVHKAAAAEAKYIEKGSPAADAILTVTPAAAVLRAEAEKGRQYGEHRHSYPGSHPAEPPAPPGPPPPPPHEGLGRKASILEPLTRPRPRDLAYSQLSPQYHSLSYSSSPEYTCRASQSIWERFRLSRRRHKEEEEFMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQHKS
The following text describes a protein:
Function:
Catalyzes the hydrolysis of L-arginine to urea and L-ornithine. The latter can be utilized in the urea cycle or as a precursor for the synthesis of both polyamines and proline.
Sequence:
MGGAAAAAGAARWIQRLSAARISTEALERGQSRVIDASLTLIRERAKLKGELLRAMGGVKASATLLGVPLGHNSSFLQGPAFAPPRIREAIWCGSTNSSTEEGKELNDPRVLTDVGDVPIQEIRDCGVEDDRLMHVISESVKTVMDEDPLRPLVLGGDHSISYPVVRAVSEKLGGPVDILHLDAHPDIYDCFEGNTYSHASSFARIMEGGYARRLLQVGLRSITKEGREQGKRFGVEQYEMRTFSRDREKLENLKLGEGVKGVYVSVDVDCLDPAFAPGVSHIEPGGLSFRDVLNILQNLQGDVVAGDVVEFNPQRDTVDGMTAMVAAKLVRELSAKISK
The following text describes a protein:
Function:
A D-serine-specific transporter, may function as a H(+) symporter.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MHSQIWVVSTLLISIVLIVLTIVKFKFHPFLALLLASFFVGTMMGMGPLDMVNAIESGIGGTLGFLAAVIGLGTILGKMMEVSGAAERIGLTLQRCRWLSVDVIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPPHPAALYVANKLGADIGSVIVYGLLVGLMASLIGGPLFLKFLGQRLPFKPVPTEFADLKVRDEKTLPSLGATLFTILLPIALMLVKTIAELNMARESGLYILVEFIGNPITAMFIAVFVAYYVLGIRQHMSMGTMLTHTENGFGSIANILLIIGAGGAFNAILKSSSLADTLAVILSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPDISPEIIAIAIGSGAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII