lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs). Involved in ribosome biosynthesis.
Miscellaneous:
MISCELLANEOUS: Present with 18200 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nucleolus. Mitochondrion. Note=Associated with ribosomal chromatin, even in the absence of transcription.
Sequence:
MSSLSDQLAQVASNNATVALDRKRRQKLHSASLIYNSKTAATQDYDFIFENASKALEELSQIEPKFAIFSRTLFSESSISLDRNVQTKEEIKDLDNAINAYLLLASSKWYLAPTLHATEWLVRRFQIHVKNTEMLLLSTLNYYQTPVFKRILSIIKLPPLFNCLSNFVRSEKPPTALTMIKLFNDMDFLKLYTSYLDQCIKHNATYTNQLLFTTCCFINVVAFNSNNDEKLNQLVPILLEISAKLLASKSKDCQIAAHTILVVFATALPLKKTIILAAMETILSNLDAKEAKHSALLTICKLFQTLKGQGNVDQLPSKIFKLFDSKFDTVSILTFLDKEDKPVCDKFITSYTRSIARYDRSKLNIILSLLKKIRLERYEVRLIITDLIYLSEILEDKSQLVELFEYFISINEDLVLKCLKSLGLTGELFEIRLTTSLFTNADVNTDIVKQLSDPVETTKKDTASFQTFLDKHSELINTTNVSMLTETGERYKKVLSLFTEAIGKGYKASSFLTSFFTTLESRITFLLRVTISPAAPTALKLISLNNIAKYINSIEKEVNIFTLVPCLICALRDASIKVRTGVKKILSLIAKRPSTKHYFLSDKLYGENVTIPMLNPKDSEAWLSGFLNEYVTENYDISRILTPKRNEKVFLMFWANQALLIPSPYAKTVLLDNLNKSPTYASSYSSLFEEFISHYLENRSSWEKSCIANKTNFEHFERSLVNLVSPKEKQSFMIDFVLSALNSDYEQLANIAAERLISIFASLNNAQKLKIVQNIVDSSSNVESSYDTVGVLQSLPLDSDIFVSILNQNSISNEMDQTDFSKRRRRRSSTSKNAFLKEEVSQLAELHLRKLTIILEALDKVRNVGSEKLLFTLLSLLSDLETLDQDGGLPVLYAQETLISCTLNTITYLKEHGCTELTNVRADILVSAIRNSASPQVQNKLLLVIGSLATLSSEVILHSVMPIFTFMGAHSIRQDDEFTTKVVERTILTVVPALIKNSKGNEKEEMEFLLLSFTTALQHVPRHRRVKLFSTLIKTLDPVKALGSFLFLIAQQYSSALVNFKIGEARILIEFIKALLVDLHVNEELSGLNDLLDIIKLLTSSKSSSEKKKSLESRVLFSNGVLNFSESEFLTFMNNTFEFINKITEETDQDYYDVRRNLRLKVYSVLLDETSDKKLIRNIREEFGTLLEGVLFFINSVELTFSCITSQENEEASDSETSLSDHTTEIKEILFKVLGNVLQILPVDEFVNAVLPLLSTSTNEDIRYHLTLVIGSKFELEGSEAIPIVNNVMKVLLDRMPLESKSVVISQVILNTMTALVSKYGKKLEGSILTQALTLATEKVSSDMTEVKISSLALITNCVQVLGVKSIAFYPKIVPPSIKLFDASLADSSNPLKEQLQVAILLLFAGLIKRIPSFLMSNILDVLHVIYFSREVDSSIRLSVISLIIENIDLKEVLKVLFRIWSTEIATSNDTVAVSLFLSTLESTVENIDKKSATSQSPIFFKLLLSLFEFRSISSFDNNTISRIEASVHEISNSYVLKMNDKVFRPLFVILVRWAFDGEGVTNAGITETERLLAFFKFFNKLQENLRGIITSYFTYLLEPVDMLLKRFISKDMENVNLRRLVINSLTSSLKFDRDEYWKSTSRFELISVSLVNQLSNIENSIGKYLVKAIGALASNNSGVDEHNQILNKLIVEHMKASCSSNEKLWAIRAMKLIYSKIGESWLVLLPQLVPVIAELLEDDDEEIEREVRTGLVKVVENVLGEPFDRYLD
The following text describes a protein:
Function:
Plays a role in cuticle calcification. May induce precipitation of the calcium stored in the posterior caeca as calcium carbonate.
Miscellaneous:
MISCELLANEOUS: Binds calcium.
Subcellular Localization:
Secreted. Note=During the premolt period, localizes to microvilli-rich apical regions and to the subnuclear region. During the postmolt period, localizes to the intercellular space, basal region of cells and calcium reabsorption spherules.
Sequence:
MNKVFIIGVCLFIVSQAVLAVPWDSDESSDERLSDRSDESREEPRKLVVSDDDSREDSNESAEVRRRDDSRESEEEPRKLSADTSDEDSDDSQESPLDLFFKTLRDSKISRAQRAALLKALLSRYAGY
The following text describes a protein:
Function:
Co-chaperone that regulates diverse cellular pathways, such as programmed cell death and stress responses.
Sequence:
MMHNSTEESEWEVRPGGMLVQRRDDAASSDHKPLQDPDSASAAFAQTIRITVSHGSSHHDLHISAHATFGDVKKALVQKTGLEASELKILFRGVERDDAEQLQAAGVKDASKLVVVVEDTNKRVEQQPPVVTKEMEKAIAAVNAVTGEVDKLSDRVVALEVAVNGGTQVAVREFDMAAELLMRQLLKLDGIEAEGDAKVQRKAEVRRIQNLQEAVDKLKARCSNPFVDQSKAAAVSTEWESFGNGVGSLNPPPPASPSANVTQDWEKFD
The following text describes a protein:
Function:
Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.
Sequence:
MPTRSKRSLASNDRKSPRISKQAKVEVVIVDKSPSKYSTASSDSIPISKLKQRNGKGRATRTKETPASKQPPKEAQKVLFSKSRKIISSDEEDEDSRDEKSSDEEWSSEEETSSEDVSKDEEELSNEESTSSDEEWGARGPVKRKKTTKPIKAAKAKKTTKPRPKKASGKAKACPKDSGKDTDAIIGANLDSDSDDDIPCASAGQYLSEYEKKRLQNIQENAAFFESIDLQSAKNNLSDVSTKKSARPRGLTRRKWEHPEVPPPRPRSLRLQNKNPEGVQLPPKPEPVPLYQDMHVERAGPTYRHFFVQKHSSVRRGLTGKHKGTPFGPRKPAGPLDMAATNVKGDGKGLADSFQQELHRLAKTPIPKGEAKERLTVTQESFLKSVQSMAITEERVAKVTPERIFSVAVHPSTTKMLVCAGDKWGRLGLWDVESQEGEDGVYSYNPHSRPINCLQFSPVHHGKLYMCSYDGTMRCAEFEKNIFSEVFSTEEGTDQLVKYFDFLSEDGTTCLVGLGDGDVAVVDTRTKGTEAEHLYPAHDRTIKTVSVHPTQRHYFVTCCNDSNVYIYDLRNMKKKGSQQFVASLYQHTRSVSSAYFSPASGSRILTTCFDDRIRLFDTKVIGQPTVKPLREIRHNNQTGRWLTPLRAVWVPGRDDLFVSGSMKQPRQMELFDDKSTLLHTYTDPDYLTSICSIIAFHPTQFLLAGGNSSGRMHVFSASSFSATSKKSPGSPRVVLKKMSV
The following text describes a protein:
Function:
Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled nucleotide excision repair (TC-NER) machinery fails to resolve DNA damage. Plays an important role in the activity of long-term repopulating hematopoietic stem cells (LT-HSCs) (By similarity). Is a regulator of stress granule assembly, required for their efficient formation. Required for proper brain development and neocortex lamination (By similarity).
Subcellular Localization:
Nucleus. Chromosome. Cytoplasm. Cytoplasm, Stress granule. Note=Associates with nuclear chromatin.
Sequence:
MMTSVGTNRARGNWEQPQNQNQTQHKQRPQATAEQIRLAQMISDHNDADFEEKVKQLIDITGKNQDECVIALHDCNGDVNRAINVLLEGNPDTHSWEMVGKKKGVSGQKDGGQTESNEEGKENRDRDRDYSRRRGGPPRRGRGASRGREFRGQENGLDGTKSGGPSGRGTERGRRGRGRGRGGSGRRGGRFSAQGMGTFNPADYAEPANTDDNYGNSSGNTWNNTGHFEPDDGTSAWRTATEEWGTEDWNEDLSETKIFTASNVSSVPLPAENVTITAGQRIDLAVLLGKTPSTMENDSSNLDPSQAPSLAQPLVFSNSKQTAISQPASGNTFSHHSMVSMLGKGFGDVGEAKGGSTTGSQFLEQFKTAQALAQLAAQHSQSGSTTTSSWDMGSTTQSPSLVQYDLKNPSDSAVHSPFTKRQAFTPSSTMMEVFLQEKSPAVATSTAAPPPPSSPLPSKSTSAPQMSPGSSDNQSSSPQPAQQKLKQQKKKASLTSKIPALAVEMPGSADISGLNLQFGALQFGSEPVLSDYESTPTTSASSSQAPSSLYTSTASESSSTISSNQSQESGYQSGPIQSTTYTSQNNAQGPLYEQRSTQTRRYPSSISSSPQKDLTQAKNGFSSVQATQLQTTQSVEGATGSAVKSDSPSTSSIPPLNETVSAASLLTTTNQHSSSLGGLSHSEEIPNTTTTQHSSTLSTQQNTLSSSTSSGRTSTSTLLHTSVESEANLHSSSSTFSTTSSTVSAPPPVVSVSSSLNSGSSLGLSLGSNSTVTASTRSSVATTSGKAPPNLPPGVPPLLPNPYIMAPGLLHAYPPQVYGYDDLQMLQTRFPLDYYSIPFPTPTTPLTGRDGSLASNPYSGDLTKFGRGDASSPAPATTLAQPQQNQTQTHHTTQQTFLNPALPPGYSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVSVNASATPFQQPSGYGSHGYNTGVSVTSSNTGVPDISGSVYSKTQQSFEKQGFHSGTPAASFNLPSALGSGGPINPATAAAYPPAPFMHILTPHQQPHSQILHHHLQQDGQTGSGQRSQTSSIPQKPQTNKSAYNSYSWGAN
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.
Subcellular Localization:
Secreted.
Sequence:
MASRAAAAVAVLALVCAVQSSLSAAAVPGLSAAFYKTSCPRLEQIVDKHVTATFNGDRGVAPALMRILFHDCFTQGCDASVLIKGPGSERETGPNRTLRPVALDLIDRIRREANATCGQVVSCADITVLATRDALVKAGGPRFPVDLGRRDSFEPATQQVGLLPLPSDDVDGLMRSFRGRNLNRDDLVALSGAHTFGVAHCGVISPRVNSANKTPLMDAQFAKDLQAKCKTDNPAVTQDLDVLTPHAFDNKYYEGLNQRKGLFKSDQFLVDHPETRNLALTFSRDQVAFFKQFAISMTKMTEMNVLTGKQGEIRAECSVAGRRPRIEAAAAAGDEGVKADM
The following text describes a protein:
Function:
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
Sequence:
MINKAILGGTFDPIHNAHINVAYEALERFNLEEVIFIPAGNPPHKIKLKKTPAHIRYEMVKLAIEKETRFSISDFEIKSKGLSYTYRTLKHFKEKEPETNWYFITGEDCLSYLEHWKYIDEIFNICNFVIFSREGFKEKEEIIKKKKSILLKYRKEILFMDASILDISSTKIRNRIKEGKEVSFYMPDKVYKFILQNNLYK
The following text describes a protein:
Function:
Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
Sequence:
MRVLVLGAGQLARMMSLAGAPLNIETIAFDVGSENIVHPLTQTVLGHGLEQAIEQVDVITAEFEHIPHPILDLCARSGKLYPSAEAIKAGGDRRLEKALLDRAQVANARYTMIRSRDDLTSAIAEIGLPMVLKSALGGYDGKGQWRLKEPTQIESVWQELAQYLAANPEQAIVAEEFVAFDREVSLVGARNLVGDVVVYPLAENVHTQGVLSLSTAIDAPALQTQAKAMFKAVAEQLNYVGVLALEFFEVQGQLLVNEIAPRVHNSGHWTQQGAETCQFENHLRAVCGLPLGSTKLVRETAMINILGEDQLPAEVLALEGCHVHWYGKAKRSGRKMGHINVTADYSGELQRKLCQLATVLDEKAFPAVHAVAKEIQP
The following text describes a protein:
Function:
Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MREDRSPILELQGITKSFGGVEALRGVDFALHPGEIHGLVGENGAGKSTLMKIIAGVHTEFSGRFLLDGKETHFRSTRDAHAAGIAMVHQELSVAPDLTVAENVFLGNQPTNALGLVQWRRMAREAGEQLARFGIDVDPMSRLGDLPIGLQQLIEIARVLFSGARIVILDEPTSALSPPEVERLFATLRRLREEGTAIVFISHFIEDILLVSDTVTVFRNGRKIAETASAATSKGALIEAMIGRGGEALEHSYTDDLMLPQPSGSSVVLKVDQLSLARSLKDISFEARAGEVLGIYGFMGCGQQELSRILFGKLKPDGGTLAVEGKPKTFASTAAARRAGVALVPESRRDMLFHQEPVYKNISISILDRISSLLLKPAQERDIARRQVEQLQIRPPVVGLDLGMLSGGNQQKVALAKWLTYPPKLLVLCEPTRGMDVGAKNDVINIVRDLRARGLAIIVLSTEPETVLSLADRILVLKRGALVREFSNEPVSKDRLLEAA
The following text describes a protein:
Function:
Alpha-mannosidase-like protein involved in endoplasmic reticulum-associated degradation (ERAD). Delivers misfolded glycoproteins to proteasomes. It lacks mannosidase activity.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MGSLHSIFCVCLILLCIFKENSIVGAINSARMVELRETSRRLFYHGYNNYMQFAFPNDELAPLSCEGLGPDYENPNNIGVNDVRGDYLLTLVDVLDTLVVLGDREGFQDAVDKVIHHINFERDTKVQVFEATIRILGGLLSSHIFASEEKYGFQIPLYKGELLTLATELAERLLPAFRTPTGIPFARINLMKGVAYREVTENCAAAASSLVLEFSMLTALTGNNKFKASAENAFFSVWKRRSGIGLLGNSIDVLSGRWIYPVSGVGAGIDSFYEYAFKSYIFLGDPRYLEVWQKSLESLRHYTASLNEYYYQNVYSANGMVMSRWVDSLSAYFPGLLVLAGELELAKKMHLYYFSIYLKFGQLPERYNLYTKSIELNGYPLRPEFAESTYYLYRATKDVFYLHVGELLLSNIENHLWTPCGFAAVENLEKYTLSNRMESFFLSETLKYLFLLFDDDNPIHRSHHDFIFTTEGHLFPVTNQTRLSTSQRIYDGGEVCVAEDYDRSKWPMLYSLIASRDDYDYVSHLVGIDNKAIPSYLIDPSGVCKRPEYSDGFELLYGSALVSPIKSVERVTNNVYISDIIGNKLKFVQKEGSNSLFLYTAGAESINENDTVFLTDPDYETFTRPDALYFDRTIAQLENPNSGQKTFGKFLQFDNDNSLPSKVFKTVLLNNSMCQKPSDTLDKDTAYIAPLGNCSWVQQAKNTNKAGLLILITDGEFINPLENIHSQNSLFNWVKPYIPPTILLKNENNFVSKWANVSVRQSDFDAPSYFQGTPVSNLYLCLKCINS
The following text describes a protein:
Function:
Essential for the organization of the actin cytoskeleton, fluid phase endocytosis and vesicle trafficking.
Subcellular Localization:
Cytoplasm, cell cortex. Cytoplasm, cytoskeleton.
Sequence:
MGIFSETVPITAVTTYIDRLTSRDTDDEDLSGIVQLSEAVNLTVTGPREASRTLRKKLKYSTPHEQVRALVILQALIENAGSHFLQNFSDEKLEDRMLQCATNSEYSKPVRKRAIHMIKLWHNDYSNVRGMESMSSLVSRLPQRQSSASHSEQPTINLKKVGPILERLIASSSMAATNLSNSLVRINPNTENPAKNKQIMVYYVDCKRAHRSLLRYIQAIQDEMWLANLLKANDEIVTAIDAFKEKCSENSDYSSDSGSYSSSYSRHLDDRASYISRSSSGGSNAQRSEDLDVNNPFGDHNRLE
The following text describes a protein:
Function:
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Subcellular Localization:
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Sequence:
MTNEINSATVTQDEVIKWSREAQSTLEKTQKICTDAQSSMQKTAQELTILIPDKLQAIEFLFKSYREQYDSILKQIETTKIYLHTNIDKVFNDIKDLLDPSLARLNNILLELKKTRVPSIVVEGTSEGKTLFDFTSIQSINLLKENIGIFKSNCSKIKNLLDLEVKEKLNIEQDRMNSRWNKSVKMYDLIAPLQLELRALIHGASNESNSFMGTILRENQALENELVSILEMQTNHFDQCMKAVELISSGNGCDMNLGVLKNDAQELPEVFKELTTIYDIILRNEERSKKFLATHMPNIEKISDIVKEELAVFRKFKTEEIPRYTFLIAECENKLKECSMPVKSDQSPSQVYTQTLQELTEHYVKFINIYKTKYLAELHHQQFTYPRKFLKKLTEFLNEDIYRIQIEESERRRQWTSRYGEFIPSEFKLPGEHELPVIVQIITEGLEYIQKEDGQEEEPNIGNEKELMDMITGSNK
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 2278 (m5C2278) in 25S rRNA. Loss of m5C2278 in 25S rRNA results in anisomycin hypersensitivity.
Miscellaneous:
MISCELLANEOUS: Present with 922 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MNFYRDATWVLEDIEKEAAKERISGSMQTLVLKSCKRYKLKSNPKHIYAVLDSCWKYKPYLEKVMKKAHILEDIPKKKGKPLFSRLTLLLLCHDLLLSKQKRIQMGKHPIKDYVLKFKSPLHSEMVKLKLKLKVRELSELVLSEDISNDLPPVRWIRINPLKCHPNGETEPVLAELRKKFTLKVDKWSELVPGSIYYDEFIPNLFGIHPSDKITAHELYKHGKIIIQDRASCFPAHILNPGPSDIVIDSCSAPGNKTTHTASYIYPEPPKDNNTRIYAFEKDPERAKVLQKMIKIAGCSPNISVNVGDFTKLATPEKYKDVTCFIVDPSCSGSGIFGRKFFDSFNRRKIDDKDDDGGIVPDEQEEFIAKEELQTRLAKLSSFQFQMVKHAMSFPAAKKIVYSTCSIHAEENERVVIDLLLDKSVREWGWKVAPKREVIPSWPRRGKVEEFEEVFRDGVTYDPQQLAEGCIRALPKSDGGIGFFAVCFERD
The following text describes a protein:
Function:
Involved in spore and ascus formation. Required for the efficient assembly of the precursors of the prospore membrane to a continuous prospore membrane.
Sequence:
MACTNDGPNKYPEIVSVKHLFQHSGSKHEFSAGKRFSKSIGKIFKRNSALKTSRTETANHKMELKKREGVTLLPPVPESLLHKLNSWLETFSSTKNMKIEENKIVINEKEIRDSVSYYPDKNGGSAVFCYLPDLVLYYKPPIKVTGKQCPIKRSPWESMEIQYQKFMYPLERLERQFEEVPFRPWYFAMRLKELYRCCERSFTNAANRGKARLLRGKQRTKKSYHKTVNLVSAKISTHSNAPSPG
The following text describes a protein:
Function:
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
Subcellular Localization:
Plastid, apicoplast.
Sequence:
MLHTLRSIQAPFTLNNTARALFAKFVRDKPHLNVGTIGHIDHGKTTLTSAITKVLAKQQLAEFQEYGKIDKAPEEKARGITINSATVEYQTKTRHYGHVDCPGHIDYVKNMITGAAKMDAAILVVAATDGCMAQTREHVLLCRQVGVETIIVFVNKIDLAKDPEIHELVEMEIRELLSKYEYDGDNAKIVKGSALLASNDQEPELGEKSILQLLETMDKEIKIPQRPIDKPFLMSIEGTYHIAGRGTVVTGTIDQGKASIKDNIEVVGYGKPKQTAIVGVETFKKQLDFGEAGDNVGILIRGLTRDDVRRGQVLCKPGSLTTHNCIESNLYILKEEEGGRKKPFPNGYRPQMFVRTADVAVTLYRYARRYLHCKLNLSYNLPLYQGQRFALREGGKTVAAGVISKILPDEVAPTSKKQILDKQEAAEKKQKEADDSKAAAAAKTAAAAAKPAAGAKAAGGAKPAAKAPPKK
The following text describes a protein:
Function:
Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain non-canonical stop codons AGG and AGA. Non-canonical termination codons AGG and AGA are found at the end of MT-CO1/COX1 and MT-ND6/ND6 open reading frames, respectively. Recognizes non-canonical stop codons via a network of interactions between the codon, MTRF1 and the ribosomal RNA (rRNA): in contrast to other translation release factors, which identify the codon in the A-site via direct interactions of amino acid side chains with the bases, MTRF1 repositions the first 2 bases of the stop codon to use an intricate network of interactions that includes residues of the release factor, the rRNA of the small ribosomal subunit, as well as neighboring bases of the mRNA.
Subcellular Localization:
Mitochondrion.
Domain:
The GGQ domain interacts with the peptidyltransferase center (PTC) of the large ribosomal subunit to trigger nascent chain hydrolysis.
Sequence:
MSHHLCIWLFRNPFLRACPQRHVFLSCQQFRQISLDTRPWNFRQKKTHVLYQLLNKSWSRGCCHQGTRKLWKHKALQKYMEDLNKEYQTLDQCLQGISENEGDRRALHRRHAQLAPLAAVYQEIQEAEQAIEELESLCKSLNKQDEKQLQELVSEERQIIDQKIHRLYSELLERLVPKEKYDWSDVILEVTSGRTTGGDICQQFTREIFDMYQNYSYYKHWKFELLNYTPADYGGLHHAAARISGDSVYKHLKYEGGIHRVQRIPEVGLSSRMQRIHTGTMSVIVLPQPDEVDVKVDPKDLRVDTFRARGAGGQHVNTTDSAVRLVHIPTGLVVECQQERSQLKNKEIALRVLRARLYQQIIEKDRCQQQNARKLQVGTRAQSERIRTYNFTQDRVTDHRIAYEVRDIKEFLRGEKCLDQLIERLLQSADEEAISEFLDESLQSVK
The following text describes a protein:
Function:
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
Sequence:
MKVFAVVVAFLVAVATAHESCYSQVDQACSKINSKPGLDQELIPCNATYGHINIVTKDLINFANTHIVRSFEYLLMATHYGNYQMNRAGFEKLFRGLSDEKWHEAIELIEQITTRGGVMEFVPPKALNGVEKTNNVYQLYEIQSVAKALDMEKKLALEAFNIHKEASGRSEGKHDPEISSYIEKEFVHDHAKTIRKLAGYVTDLKSILSGPDGSLGLFLFDEYLQKQ
The following text describes a protein:
Function:
Ligand for cxcr3.2. Chemotactic for macrophages.
Subcellular Localization:
Secreted.
Sequence:
MTQKASLLLATLAICCIATSYALPMEGIISDLKCRCVRYTSAYINPRNFRHIEIIPQGARCRRTEIIVTLRNNNIVCVDPQAQWINQLISNV
The following text describes a protein:
Function:
May act as a regulatory subunit for mtm-6. In association with phosphatase mtm-6, plays a role in endosome trafficking probably by regulating phosphatidylinositol-3-phosphate levels. Regulates fluid phase endocytosis in coelomocytes. Regulates posterior migration of QL neuroblast descendants and the anterior migration of QR neuroblast descendants and HSN neurons during larval development probably by controlling Wnt ligand secretion through the regulation of sorting receptor mig-14 trafficking. Involved in the formation of correct synapse number in DA9 motor neurons.
Subcellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein.
Sequence:
MELSELIEVTRVRDAFMRKGPRPAQVGDICIFGHHLIFAPTTVGKEVPDNAEEFWLLHKAVDRVLCEPISKENPQRGGLLALKCKNFLLIIFEIGDLEICRATARTIESLSNINGFLHDYAFFYNSPFTILDDGWSAFDLEQEFARLMLSTDAFRISSVNENFAICPTYPEKLIVPKGIGDDYLKISATFREGGRFPVLSYFHKETKSPLVRCSQPLIGPTNRRCREDETILNSMITVNRGYIIDTRSKSSATAAKAKGGGAEPQGNYRQWRYIQCPIPRQREIHDALTRMVDVCSERKVTSDRWVSRVGQAGWLSSVAASLEAAANVAQCIYNERLEEVPVVIHGGDGLDSTLIASSLAQILLDADARTIRGFESVIEREWICGGHPFSLRNNHCAYAEGTVTGPFESPVFLVFLDAVHQMIAQYPMSFEFDENFLIFLFEHAYASEFGSFLGNCEKEKKDNGIRKKTVSLWSHVHHPENMKQFVNVCYDPTPGVIWPSIAPQCIKIWDRLFFRWQRPDNSWSTPETETIQSLADHWKLREKELIAKASSLRRSVVELSRELRVLSPM
The following text describes a protein:
Function:
Cytokine produced by various cells such as eosinophils, T-helper type 2 (Th2) cells or epithelial cells that plays a role in internal safety of adaptive immune responses by regulating cytokine production. Promotes and augments T-helper type 2 responses locally or systemically. Exerts its activity via its receptor composed of IL17RA and IL17RB for signal transduction. In turn, stimulates the JAK2-STAT5A pathway and promotes the secretion of type-2 associated cytokines including IL4, IL9 and IL13. Also induces the release of IL8, and IL6 from eosinophils through the combined activation of MAPK and NF-kappa-B pathways. Inhibits the differentiation of T-helper (Th17) cells via the production of IL4, IL5 and IL13.
Subcellular Localization:
Secreted.
Sequence:
MYQAVAFLAMIVGTHTVSLRIQEGCSHLPSCCPSKEQEPPEEWLKWSSASVSPPEPLSHTHHAESCRASKDGPLNSRAISPWSYELDRDLNRVPQDLYHARCLCPHCVSLQTGSHMDPLGNSVPLYHNQTVFYRRPCHGEEGTHRRYCLERRLYRVSLACVCVRPRVMA
The following text describes a protein:
Function:
DNA-dependent ATPase, stimulated equally by ss- and dsDNA. Has both ATPase and helicase activities, and translocates along ssDNA displacing bound streptavidin. Its essentiality for growth does not depend on its helicase activity.
Sequence:
MSIASDPLIAGLDDQQREAVLAPRGPVCVLAGAGTGKTRTITHRIASLVASGHVAAGQVLAVTFTQRAAGEMRSRLRALDAAARTGSGVGAVQALTFHAAAYRQLRYFWSRVIADTGWQLLDSKFAVVARAASRTRLHASTDDVRDLAGEIEWAKASLIGPEEYVTAVAAARRDPPLDAAQIAAVYSEYEALKARGDGVTLLDFDDLLLHTAAAIENDAAVAEEFQDRYRCFVVDEYQDVTPLQQRVLSAWLGDRDDLTVVGDANQTIYSFTGASPRFLLDFSRRFPDAAVVRLERDYRSTPQVVSLANRVIAAARGRVAGSKLRLSGQREPGPVPSFHEHSDEPAEAATVAASIARLIASGTPPSEVAILYRVNAQSEVYEEALTQAGIAYQVRGGEGFFNRQEIKQALLALQRVSERDTDAALSDVVRAVLAPLGLTAQPPVGTRARERWEALTALAELVDDELAQRPALQLPGLLAELRRRAEARHPPVVQGVTLASLHAAKGLEWDAVFLVGLADGTLPISHALAHGPNSEPVEEERRLLYVGITRARVHLALSWALSRSPGGRQSRKPSRFLNGIAPQTRADPVPGTSRRNRGAAARCRICNNELNTSAAVMLRRCETCAADVDEELLLQLKSWRLSTAKEQNVPAYVVFTDNTLIAIAELLPTDDAALIAIPGIGARKLEQYGSDVLQLVRGRT
The following text describes a protein:
Function:
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the third and last glucose residue from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide intermediate Glc(2)Man(9)GlcNAc(2)-PP-Dol to produce Glc(3)Man(9)GlcNAc(2)-PP-Dol.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSILVLIATLLAFALPVAYLVNGIVPDPYMDEIFHVPQAQRYCKRDFYTWDPMITTLPGLYLVSLVFESMVSWIPGMDLCTLNALRSINILLSLVCVCLFRSILLHLDPKVSERALLLKSVVLALYPLHWFFTFLYYTDVGSTAAVMAMYLACLKRSYWISATLSILAIMFRQTNAVWTVFGLCVGVIQFLQEAISSSKEEEAVDDTEKTPDKRYSESKFLRRRLHVCIGSHFYSGRHSDLQDAILNAWQRKWFAARQFSPFVLVILAFLAFVVYNGSIVVGAKDAHRASPHFAQPLYFALFTAGVLAPLQLSLNRFSSLRQVFRETPALACLSGAVTASIAIVAVHFFSLAHPYLIADNRHYTFYIWKDIIQTHWCVKYLLIPLYIFCWWSIIHSLLENLRDAGVRTPLLQKLWVVSFCGAVIAVLVPAPLVEFRYFTVPFYLVALHSFAKLQVSSWKFWFMAMEFLVVNALTMRLFLWKPFHWAHEPGTQRFIW
The following text describes a protein:
Function:
Lectin that specifically binds to L-fucose. Has strongest preference for the alpha-1,6-fucosylated chain (core fucose) on glycoproteins among alpha-1,2-, alpha-1,3-, alpha-1,4-, and alpha-1,6-fucosylated chains. Might play a role in the differentiation of the fruiting body. Exhibits antifungal activity against Mucor racemosus and thus could act as an antifungal protein in natural ecosystems.
Domain:
AAL adopts the six-bladed beta-propeller fold and contains 5 binding sites per monomer, each located between two adjacent blades. Residues conserved at 5 of the 6 sites, are located on the surface of the AAL and directly contribute to fucose recognition. Because the corresponding residues forming site 6 are not conserved, this site cannot be considered to accommodate fucose molecules. The 5 binding sites that are non-equivalent, and owing to minor differences in amino-acid composition they exhibit a marked difference in specific ligand recognition.
Sequence:
MPTEFLYTSKIAAISWAATGGRQQRVYFQDLNGKIREAQRGGDNPWTGGSSQNVIGEAKLFSPLAAVTWKSAQGIQIRVYCVNKDNILSEFVYDGSKWITGQLGSVGVKVGSNSKLAALQWGGSESAPPNIRVYYQKSNGSGSSIHEYVWSGKWTAGASFGSTVPGTGIGATAIGPGRLRIYYQATDNKIREHCWDSNSWYVGGFSASASAGVSIAAISWGSTPNIRVYWQKGREELYEAAYGGSWNTPGQIKDASRPTPSLPDTFIAANSSGNIDISVFFQASGVSLQQWQWISGKGWSIGAVVPTGTPAGW
The following text describes a protein:
Function:
Endoribonuclease that plays a central role in rRNA processing and mRNA decay, and probably tRNA processing. Acts on 9S rRNA (the precursor of 5S rRNA) and RNAI, a molecule that controls the replication of ColE1 plasmid. Upon expression in E.coli does not purify with endogenous degradosome proteins. Prefers 5'-monophosphorylated substrates over 5'-triphosphorylated substrates. Complements an rne temperature-sensitive mutation in E.coli, despite being considerably shorter and not able to interact with the E.coli degradosome. Cleaves AU-rich sequences in vitro, tested with psbA2 mRNA. Complements both an rne temperature-sensitive mutation and an rng deletion in E.coli. Acts in the degradation of psaL mRNA in the presence but not the absence of the sRNA PsrR1. Cleaves the rimO-crhR transcript, contributing to the very short half-life of rimO mRNA; mRNA for psbA2, one of the core proteins in photosystem II, is degraded in the dark under control of a cis-acting AU-rich box in its 5'-UTR. RNase E cuts in this box, suggesting it is involved in this dark-induced mRNA instability; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Endogenous RNase E is required for correct processing of pre-crRNA for the CRISPR3 subtype III-B system in this genome (genes sll7080 to sll7095). This CRISPR3 system does not include a cas6 gene, which is the usual RNase involved in crRNA maturation.
Subcellular Localization:
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Subcellular locations are shown upon expression in E.coli of the N-terminal domain (residues 1-396). Some of the protein cosediments with polysomes.
Sequence:
MPKQIVIAEKHQVAAVFWKDQIQELVVSTGSQQVGDIYLGLVDNILPSIDAAFINIGDTEKNGFIHVSDLGPVRLRRTAGSISELLSPQQRVLVQVMKEPTGNKGPRLTGNISMPGRYMVLMPYGRGVNLSRRINREEERSRLRALAVLIKPPGMGLLVRTEAEDVPEDAIIEDLENLQKQWELVQQQAMTRSAPMLLDRDDDFIKRVLRDMYSSEVNRIVVDTPAGMKRIKQQLMNWDQGRLPEGVLIDCHRESLSILEYFRVNATIREALKPRVDLPSGGYIIIEPTEALTVIDVNSGSFTHSANSRETVLWTNYEAATEIARQLKLRNIGGVIIIDFIDMDSHKDQLQLLEHFNRCLETDKARPQIAQLTELGLVELTRKRQGQNLYELFGQPCPECGGLGHLVELPGEKGFVSLSPTAVNSSIPPRLVEKPILSPPVAKVNDLPKKEEAKISSPLDLLFHPNYQEQGDRDSNRRRRRRRGSEFSEKENIKSVGISRSKGPSPSPTKEKVTGTAPPRRERPSRRVEKTLVPVDVAMTTLEQDIYARMGISPLIKTEYADQDPRSFMVSVVTAGAALEGNTNGSGSLVNAVITTVDNGDNGDNVPSDGLTIVSEVTAPTPVIEQPREETVEPEQVVLPQLDDETPAAPVAEESAPIETKKRPGRRRRRSSAE