lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Chemokine released during platelet aggregation that plays a role in different biological processes including hematopoiesis, cell proliferation, differentiation, and activation. Acts via different functional receptors including CCR1, CXCR3A or CXCR3B. Upon interaction with CXCR3A receptor, induces activated T-lymphocytes migration mediated via downstream Ras/extracellular signal-regulated kinase (ERK) signaling. Neutralizes the anticoagulant effect of heparin by binding more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Plays a role in the inhibition of hematopoiesis and in the maintenance of hematopoietic stem cell (HSC) quiescence. Chemotactic for neutrophils and monocytes via CCR1. Inhibits endothelial cell proliferation. In cooperation with toll-like receptor 8/TLR8, induces chromatin remodeling and activates inflammatory gene expression via the TBK1-IRF5 axis. In addition, induces myofibroblast differentiation and collagen synthesis in different precursor cells, including endothelial cells, by stimulating endothelial-to-mesenchymal transition.
Subcellular Localization:
Secreted.
Sequence:
SDDPKESEGDLHCVCVKTTRLVRPGHITXL
The following text describes a protein:
Function:
Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.
Subcellular Localization:
Nucleus.
Sequence:
MSTDLTQLHHLFLHAMLLRRVASYEKWLEVWKKSARILGINVSDNGFVQFYGEINDRIERFGFRIDLLCEEGNGPIDMDQIEQDTADNRRLKTKRWMALVNTRSDDSAKLGTEFNPTEISFYKKIVDNIILSANYRYCLSRHDCLRLTTTLQASLKKSDAEKCLRILVKKGWLNESRTGCYSLSIRAKLELKSYIEENYNEEDRPPQCAACREIVMRGFKCPNSECPKAMHVTCIINQSRQAHICPSCRSPFNYRTLIGEDAPKGESRATVDDEDDDPENESTQTTIEPNERRRSKRARIQSTQEPDELDDHDA
The following text describes a protein:
Function:
Probable trans-acting positive activator for the tdc operon.
Sequence:
MSKFSNFIINKPFSVINNAACHIFSRYLLENKHLFYQYFKISNTCIDHLEQLINVNFFSSDRTSFCECNRFP
The following text describes a protein:
Function:
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MCMWACPSVQFVTFGFPAFCRRLPFFIDRLVVRIFFQSNSTQTVPLTLINTSPTTMKTSIILFMVTLWSLVLGGLTNNELLKLVKNRKTKVLELNDENFENILNGQRDYHLIALLTSEAPNLNCVLCRELAPEYTIVANSWFQDHPNGVAEVELTEQEEKDGKKQPKNIYFFKSEFKDSKKLFSVLQLQNIPKMFYFPPTKHLGPNNYLREKVEYQFFHGDHKELLKNWLIEVTDHRFNLYIPVNKTKIAINAIGTFIVVLLLRIFSKQVIQVITSRVIWCAASIISVILFTTGYMFNQIRGTPYVMEHRDGRTEYFAPGQQSQFGVETQIMSFLYGFLSILVIVLVKRAPEIKNQSANLFLVATISSLIFVSFSLLLSIFGVKGVGFPYRFINFL
The following text describes a protein:
Function:
Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MKRIIRISFTDAEATDSSSDEDTEERGGASQTRRRGKRLVKEIVIDPSDSADKLDVCKTRFKIRIPAEFLKTAKTEKKYRGVRQRPWGKWVAEIRCGRGACKGRRDRLWLGTFNTAEEAALAYDNASIKLIGPHAPTNFGLPAENQEDKTVIGASEVARGA
The following text describes a protein:
Function:
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development. Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis.
Subcellular Localization:
Cytoplasm.
Sequence:
MSHYHFIKCCCFQLCNVFRSHEMEIDQCLLESLPLGQRQRLVKRMRCEQIKAYYEREKAFQKQEGFLKRLKHAKNPKVHFDLADMIQDAIIHHNDKEVLRLLKEGADPHTLVSSGGSLLHLCARYDNAFIAEILIDRGVNVNHQDEDFWTPMHIACACDNPDIVLLLVLAGANVLLQDVNGNIPLDYAVEGTESSSILLTYLDENGVDLTSLRQMKLQRPMSMLTDVKHFLSSGGNVNEKNDEGVTLLHMACASGYKEVVSLILEHGGDLNIVDDQYWTPLHLAAKYGQANLVKLLLMHQANPHLVNCNEEKPSDIAASEFIEEMLLKAEIAWEEKMKEPLSVSTLAQEEPYEEIMHDLPVLSSKLSPLVLPIAKQDSLLEKDIMFKDATKGLCMQQSQDSTPENPTMGGSTKPEQVKLMPPAPNDDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSGKLCSSLPPHLFSCVERAFHQLFQEQRPQCFILSGERGSGKSEASKQIIRHLTCRAASSRAMLDSRFKHVMCILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEKSRLVSQPLGQSNFLIFSLLMDGLSAEEKHGLHLNNLCAHRYLNQTMQDDVSTGERSLNREKLAVLKQALNVVGFSNLEVENLFVILAAILHLGDIRFTALTEGNSAFVSDLQLLEQVAGMLQVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFLVNTMNSCLLSQDEQRSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLHEQVECVQEGVTMETAYSPGNQNGVLDFFFQKPSGFLTLLDEESQMIWSMESNFPKKLQSLLESSNTNAVYSPLKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQNLLFVMKTSENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKNYLELSKLLKKKGTSTFLQRLERGDPVTIASQLRKSLTDIIGKLQKCTPHFIHCIRPNNSKLPDTFDNFYVSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTFLREKKEHLAAERCRLVLQQCKLQGWQMGVRKVFLKYWHADQLNDLCLQLQRKIITCQKVIRGFLARQHLLQKISIRQQEVTSINSFLQNTEDMGLKTYDALVIQNASDIARENDRLRSEMNAPYHKEKLEVRNTQEEGSKRTEDKSGPRHFHPSSMSVCMAVDGLGQCLAGPSIWSPSLHSVFSMDDNSSLPSPRKQPPPKPKRDPNTRLSASYEAVSACLSAAREAANEALARPRPHSDDYSTMKKIPPRKPKRSPNTKLSGSYEEISGSRPGDARPPGAPGTAARVLTPGTPQCALPPATPPGDEDDGEPVYIEMLGHPARPDSPDPGESVYEEMKCCLPDDGGPGAGSFLRASPPLLHGAPEDEAAGPPGDMCDIPPPFPNLLPHRPPLLVFPPTPVTCSPASDESPLTPLEVKKLPVLETNLKYPVQSEGSSPLSPQYSKSQKGDGDRPASPGLALFNGSGRASPPSTPPPPPPGPPPAPFRPCAHLAFPPEPAPVSLGKAGPSTEAPKVHPKPNSAPGAGSCSSFPKIPYSPVKAARVDARKAGSSASPPAPYSPPSSRPLSSPLDELASLFNSGRSVLRKSAAGRKIREAEGFETNMNLSSRDDPSTSEITSETQDRNANNHGIQLSNSLSSAITAENGNSISNGLPEEDGYSRLSISGTGTSTFQRHRDSHTTQVIHQLRLSENESVALQELLDWRRKLCEEGQDWQQILHHAEPRVPPPPPCKKPSLLKKPEGASCNRLPSELWDTTI
The following text describes a protein:
Function:
Has low D-gluconate dehydratase activity (in vitro), suggesting that it has no significant role in D-gluconate degradation in vivo. Has no detectable activity with a panel of 70 other acid sugars (in vitro).
Sequence:
MSNLKITNVKTILTAPGGIDLAVVKIETNEPGLYGLGCATFTQRIFAVKSAIDEYMAPFLVGKDPTRIEDIWQSGVVSGYWRNGPIMNNALSGVDMALWDIKGKLAGMPVYDLLGGKCRDGIPLYCHTDGGDEVEVEDNIRARMEEGYQYVRCQMGMYGGAGTDDLKLIATQLARAKNIQPKRSPRSKTPGIYFDPDAYAKSVPRLFDHLRNKLGFGIEFIHDVHERVTPVTAINLAKTLEQYQLFYLEDPVAPENIDWLKMLRQQSSTPISMGELFVNVNEWKPLIDNRLIDYIRCHVSTIGGITPAKKLAVYSELNGVRTAWHGPGDISPVGVCANMHLDLSSPNFGIQEYTPMNDALRDVFPGCPEIDHGYAYLNDKPGLGIDIDEAKAAKYPCEGGIPSWTMARTPDGTASRP
The following text describes a protein:
Function:
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
Sequence:
MTDGKFPTNIEPKYIPYSKDHASLTACANPIPLDLKSLFPNNTVVVTAVPGAFTPTCTEQHIPDYLKHLKDFKDKGVKKIIVLSANDPFVMAAWAKALGYTDEENYVIFATDPNASISKELGDGFVADLTSAGMGLRLQRYASIVVNGEITYLETEDSLGFSEISSAETILKRIHN
The following text describes a protein:
Function:
Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation.
Subcellular Localization:
Cytoplasm. Nucleus, Cajal body. Nucleus, nucleolus.
Sequence:
MALVTEVRLQNRKTREPVKGKKNKRRRLAEGECETADACADLYEAAQAQMEKEMKAAGMEGSLPMSFGGGSREKASRKRKRQLEDEEAQGPAEEHEEVEAEEDEDATGDTEGGQVAEEDRPKTETTIVDKVRVVYDSDGEVAERVVEKVEVTSEVKPEQQSIHELQHKNSDTAAGKKKKKKKKEYPVPKDIVKFYVQRHVLFEKFEDGIELDHESWYSVTPQLIAEHIAKRLSCDIVVDPFAGCGGNVIQLAMTCKQVIAIDIDPEKIRMAKHNAAIYGVADKIEWIVGNSIDILPNVKADAVFLSPPWGGVNYSRKHFSLEDMVVKGVSGLDLFAKAQQVSKNIAYYLPRGTPTSDLEALTPDEPVECEKIFLNKQLKVVTAYYGDLVTSKNQVEEAASPNEEAADR
The following text describes a protein:
Function:
Antagonises the activities of multiple heterochronic microRNAs such as lin-4 and let-7 miRNAs. Modulates gene expression and cell fate specification during development. Plays a role in, but not strictly required for, the formation of stress granules. May be involved in protein translation and reducing the expression of mature microRNAs.
Subcellular Localization:
Cytoplasm, Stress granule.
Sequence:
MGIKGDKKATSDQARLARLTLEGNSGNEEDIQFMIKTIIETTGCTQAQAEIALLDTDNNLYGAIDHILDAGDKLDSWTEQKGAKKEKKKPEEGSYNNRGFVARGRGGGTGFVDRGGRGRSNGAPRESRDNNRDNRDNKEGAAPRSTRGGFEKPYVGRGGRGGARGGYSRAVAPSSALEPDAFTADLDENQTKVDTTVTEVQPPVEESVTATVPTSSAPAPISFAAVAAAAHRKEALRKHQAQNPQPAAPPRRSLSPQPPLPSVAPVKEEPAAAPVFFEPETSHQPEKEDGFFQNESSVLAEEQTPNVSTHHDENVQSTPEPNQAWTTQLKTDLGIGLSEAPGLGLSPIPSAAPVQIIPDPGVEFVGTTAPTNIHDYSFGFVEAAPSPQLPSTESSAASISNASENIFNSSRIMPKQVEPERTSIPNGDYNLKSTSPPLSYGQSNRGLSYDTSSASYQPTDRMAPNKFNNSGPLPTQQSAQQHQPQQQQQQAPQQPVQQQQQTPPAQSQPTGHPQQHPHMMFTQQLPYAPYMNNYMNMYNPMPGVRDEQYTAALMQYGMGVDLTSLLPTAPLSQAASAQQVQSGQQRETHGLMDFNKFGSQSSRDQQPQQASNVGPPPGFQATNYMQQPNLSSLFMQQYSPAPHQFTPFMNMMPNVGSSAGGRQLYGQDDERKSYDKMSGSKPAAQQNQHSQYQHNGGNLGKYGMNKPYNWSN
The following text describes a protein:
Function:
Probable transcription factor that acts with partial redundancy with HULK1 and HULK3. Plays diverse and essential roles in the control of plant development, physiology and flowering time.
Subcellular Localization:
Nucleus.
Sequence:
MAPSRRKGGGKAAAVAAACRKRKVGDLVLAKVKGFPAWPAVVSEPEKWDASPDSKKVFVHFFGTQQIAFCNPGDVEAFTEERKQSLLTRRHAKGSDFVRAVKEIIESYEKLKQQERASDPKSAEEGTLGSAENTTLMPQVIEIPTATSLTQMNSDPSHGRDESTLLNEDASAAEQMLALRDNSGPRNKACDSAVVKEPRKIATYSSRKRNGGVRSQNCAPQNETCPVQRSKSPSRLQTEKLQSSMLQNSDGGQTIDDVEDGALRREKRIRRSSGHSESDDVATSSLNSHGSDEENASEIATVESDNNRNEGNGVDSGSKVEQIDIGGKFLEGDYDLNKGLNFQINIMVKRKKRKPTRKRGTSDVVDPQAKVEGEAVPEAGARNNVQTSQNSHEKFTERPCEENGDEHLPLVKRARVRMSRAFYGNHEANSSLQAEERSPKDTVVSATAQTSPSDIISSHDTFAVEESKFFEVSAKLSGDMVNVAPSPVEKSHDGMSPSEACVQTVREREYAMGWNELSKTPDDKSAGPQYNQVSSLPAGEAQTASVPEAVCPEVLKLLTSESDLPAVQYCQVAKIEPSMDPNTVDSSANNASEICSLSIPSQLSGQDRSNDQDACVSLENSREYLNEEGSKIDACVAQVVQSEAIEHSPSSCLVVNKQETENMPKTVNMLLKEGHGSLGEECAIVEPAQCTPNLPISATESDVIVGENVPLNEIGCTKCEDAVEDSRQLKMIGETNDQKQQVQTNNSVLVSENLSREKMSFSPAITADTPARGTPHSSSVYYHISTSESANDMQNNSSGSPNIPTGEKKNDCDAIVKEEEKIETGVCQGQKVVSCDVQSTRESYEDALCSLVRTKESIGRATCLAMDLMKFGVSAKAMEILAHTLESESNLKRRVDLFFLVDSIAQCSKGLKGDTGCVYLSAIQVILPRLLAAAVPAGATTQENRKQCLKVLKLWLERRILPESIVRHHIRELDSHSIVPACLYSRRSARTERSLDDPVRDMEDMLVDEYGSNSTLQLPGFCMPALLKDEEGGSDSEGGCDSEGGSDSDGGDFESVTPEHESRILEENVSSSTAERHTLILEDVDGELEMEDVAPPWGTENCTHTDQADNTKVSNCQLGQQHRPVFGTSHQHMSLSSPPLPSSSPPPPPAPPSQQGECAMPDSYLNGFENGGYRNVHGDQQAGPLRMNPPLSGSTMHYQGPESSYISGVQLTNSIPQADGSNFQHRPYPSHPHPHPPPPPPPPQHQFSFREPGHVLKSHRDAPSYSHRSHYVPNCDERNFHDNHERMRHAPFENRDNWRYPPSSSYGSRYQDEHKAPYPSSSYNGVRWDNPPRQYNNRPSFHPKPHSEGPAPVGMRDPGMWHQRSD
The following text describes a protein:
Function:
Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MEQSYILAPAEVLKHFDVTERSGLSSAQVSHSRQKYGPNALAEEPPTPLWELVLEQFKDQLVLILLGSAAVSFVLALFEESDDWTVFVDPAVILTILILNAIVGVTQESSAEKAIAALQEYSANEAKVVRDGVVQRIKAEDLVPGDIVHVAVGDRVPADCRLLAIHSNSFRVDQAILTGESESVAKDTRAVSDRQAVKQDQTNILFSGTTVVNGNATAVVVLTGSSTAIGDIHESITSQISEPTPLKQKLNDFGDMLAKVITVICILVWVINIEHFNDPSHGGWAKGAIYYLKIAVSLGVAAIPEGLAVVITTCLALGTRKMAQKNAVVRSLPSVETLGSCSVICSDKTGTLTTNQMSVGKIVYLSQLGTGVEVIDVEGTTFAPEGSLSYNGQVVTNLAASSSTIRQMAEVMARCNAAAIAYDEKTGTFSCIGEPTEGALRVLVEKIGTDDAAMNDKLLSLPASQKLHVSSAYYESRLPLQATYEFSRDRKSMSVLVGTGSNRRLLVKGAPESILERCSYALLGPNGARVSLTKAHLDLLSSEVVEYASRGLRVIALASVDDVGANPLIHKASTSEEYAQLEQNMTLIGLVAMLDPPRVEVADSIKKCAEAGIRVIVITGDNQNTAESICREIGVFGKDEDLKGKSFTGREFDSLSHNEQLEAVKSASLFSRTEPSHKSKLVDLLQSLGHVVAMTGDGVNDAPALKKSDIGVAMGTGTDVAKLAADMVLVDDNFATITTAVEEGRSIYSNTQQFIRYLISSNIGEVVSIFLTAALGMPEALVPVQLLWVNLVTDGLPATALSFNPADHDVMRRPPRKRDEPLVGGWLLFRYLVIGTYVGAATVFGYVWWFLYNPEGPQISFWQLSHFHKCSTEFPEIGCEMFSNDMSRSASTVSLSILVVIEMLNAMNALSSSESLLTFGLWNNMMLVYAIILSMTLHFAILYIPFLQGLFAILPLDWTEWKAVLAISAPVVVIDEILKVVERRLYNTTVTAPVKENGAILKPKKA
The following text describes a protein:
Function:
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Can also hydrolyze 3-hydroxyphenylacetyl-CoA and 3,4-dihydroxyphenylacetyl-CoA (in vitro). May play a role in controlling adaptive thermogenesis.
Subcellular Localization:
Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytosol. Mitochondrion. Nucleus.
Sequence:
MLRDVRKWNMEKAKEFLQLNKEEAETVLRLNIQPTRVGSQCSFYEDFALRGIRVDTVQPGFVSCTLKVPPRLSDKSGNLAKGAVANLVDEVGAAVVHVEGLPMNVSVDMSISFLGTAKLNDELEITSKVLGQRGSYSGTIVLVRNKATGELIAEGRHSLFGKKSSKL
The following text describes a protein:
Function:
Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
Miscellaneous:
MISCELLANEOUS: There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).
Subcellular Localization:
Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix.
Sequence:
MSTSGPRAFSSRFASFIDKVRWSLLQQQKSNMDNMFESYINNLRDVDEAYMNKVELESRLEGLTDEINFLRQIHEEEIRSLDMDSIIAEVRHGDDLRRLALDIEIATYRK
The following text describes a protein:
Function:
This protein specifies the body segmentation pattern. It is required for the development of the central nervous system. Transcriptional regulator that represses activated promoters. Wg signaling operates by inactivating the SGG repression of EN autoactivation.
Subcellular Localization:
Nucleus.
Sequence:
MALEDRCSPQSAPSPITLQMQHLHHQQQQQQQQQQQMQHLHQLQQLQQLHQQQLAAGVFHHPAMAFDAAAAAAAAAAAAAAHAHAAALQQRLSGSGSPASCSTPASSTPLTIKEEESDSVIGDMSFHNQTHTTNEEEEAEEDDDIDVDVDDTSAGGRLPPPAHQQQSTAKPSLAFSISNILSDRFGDVQKPGKSMENQASIFRPFEASRSQTATPSAFTRVDLLEFSRQQQAAAAAATAAMMLERANFLNCFNPAAYPRIHEEIVQSRLRRSAANAVIPPPMSSKMSDANPEKSALGSLCKAVSQIGQPAAPTMTQPPLSSSASSLASPPPASNASTISSTSSVATSSSSSSSGCSSAASSLNSSPSSRLGASGSGVNASSPQPQPIPPPSAVSRDSGMESSDDTRSETGSTTTEGGKNEMWPAWVYCTRYSDRPSSGPRYRRPKQPKDKTNDEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKKSTGSKNPLALQLMAQGLYNHTTVPLTKEEEELEMRMNGQIP
The following text describes a protein:
Function:
Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.
Sequence:
MFRKLKDYVSKILCWFRLYEVNRTPDNDTEKGQVGVNSEESTTPDEDNEAPWTFEILWDVVANVADLFTINGEKNILIGRYRPDKAADEILHAEFPRDSPLAVAVEAVRDKGFKVITGKWLIRDRPPAIVFHVESARDMFGDRYVEMFKKDHMIDIPAHDQEARDAVIFEYMVAEFLTEFELRCRPESSNGSNPTTGLDPSLGDTKQPSHQDEPTQPSIVPSDIEREPSGDEICTQFHDWKCAVGLVLLRQWSSRITTIFTLKTSCLEGDFHSQERAHEEARRRGIFHRFSMELAAALASNIFTPISETVAEQAEVVLGKHPDCVITQD
The following text describes a protein:
Function:
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
Subcellular Localization:
Cytoplasm.
Sequence:
MKLGPGKKAPDEINVFIEIPMGSNIKYEYDEEEDIIKVDRVLYTSMVYPFNYGFIPETLEEDGDPLDVLVLGNYSLMPGTVIEARPIGMIYMRDEEGEDAKVIAVPRNKTDPSFSNINDVKDLPEAIRNKIVHFFEHYKELEPNKWVKISGWGSVAEAKERIKKAIERKKQG
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Subcellular Localization:
Cytoplasm.
Sequence:
MAEHTPSQLLAQPEDPHRSTPGRREREEEEEGGRARRSQAATEELVEKIDYVDPQRCLRLRQKSSKTVIESGQEGQATVDDGIPLKRIQGPADVEAFFNSIALDRLLQVLLNISNRIARFGILENDRQVSYLKTSLEQSPTVRAVVGIFERLDQWITEIPLDPTPQRFGNKAFKIWGHRLESEAQNLHTQAGVITEYHKPIETELLHHFKTSFGSFGRLDYGTGHELSFLAYLSILHLTRILQPKEFILSGLIIYQKYFNLCRRLQRVYNLEPAGSKGVYGLDDFFHVVYIFGSAQLLYHPTIRPSSILDEKLMSRVNETEPGGGGGGGGLAESSSDFLRREGLTRSLFFEAVQNTLSLKTRPIPKDSLPKTTTTTTTTMRMGEQRHEEGSEQQGLLDHSPILLNLATNVKGWPKIYGGLIKMMKGEIFAKVPVMQHFWVAGPTAVLPWLACPPTIPGSLPLDHQDQQHADEPDLDYINHYRPLS
The following text describes a protein:
Function:
Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Sequence:
MINNGKMFAFRNFNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNDNNNSKDNINNNKNKNNNMDNDDNNDGGTKEKFSFSKHDEYHLNSLKRELKLEFYRISDENFSEAPYFKFLEELVAELPLLALSPEVFSYLFKELSGYPLDSIIEKIGDKNKFPFCQYEWTKKACFFRCKDCAVTDTSCVCLACFKNGDHIKNNHAFMVEESGLGGCCDCGNADSFKPHGFCKDHFTPEKIEHPSDNLDKEIKMSVHLTMRFFIKYLLHLLRIVSKPNLKQFSKYKKNDIQRIFRQYVENEAIKKEKKLFKDRTREYLKQQRLMYERHILHQLERDRDAREAREERNQNENNTDSDEDDSDDDNNNNNNNNNNNNNIVLNINNNNINININNNNNNHIGIVERLRQQFEFFQGGNLIIRDQNDLDFENDEEEENNSDDEPIQNPPEQIFNNLLYNPRDVIGNLIEHIFGANDDEAQPMDTNSDGNNEEEEEEIRVEEEEEEEEDYGNNCDLYLATESDGEYSYSNDGRNKRKKIYREKESDSYGLDINSDDNETPDEDDEKEDEDEYFEGSDNEEDEPEDIKFKEFEPTLFGKNFINPKGSVPLNKSQNLNASLTNKVVIRKFLRKLTLSIANNLLRWIDSVARSSYPILYIISEEFSRRQLDPNNFELYSPIELPYLDKISYQKDTFGNSMGYVLSLVDSRASVLMIFRPLIISLLGNRFFKFLFCEEFLKTYKLLALSSNRRIRSLISAISCQMFELPSIAVPFCTGYSKQNLFSTLAKTLLSLVQMKSEYDLSTPTGRKKYENEFYSNQDYSYISNIFKHDKNCKFLYENSEYIDDLLKITNEIQLIVPVVRKIKCAMEYELSVLSNVVSIECQSFITFDTFFHSLSKQSIPIHKYFDILLNHLNDSISKYNSTPLSPNDSRLIKNNNNNNNNNNNNNNNNNNSIGNNSNPTTTTTTTTTTTTTTTTATTNPASPKPMVTQTFSKFNLLFPQSDIFNGVAPVQLHLPTNRLIGVYILNAIELKDYSVEQIKSKLPFDSLVFLATQSMLPSVLIHQFHSHLWERNLNISEFNSYYLWSLLSLDNTLVQYCSILLGPKYFMLLCLSNFTSNFKEIESNPNAISQFFKYLISIIQHRKQATFGEKEARYHVIQALTFNVNNFSRLSDQRKEFSQYNNVENVIKQVSQPKDGNLVLKPEYWNRFDIYYPYHYFDPSSGTSKSLANYYEYLKQIKHPIPESYPLPMVNDPLPDNLKDVEKILDDPLLFSIISAIISKFLYPKYEMVSNFTFSVHSNNDFSDNVLNRCIAQFLSTDRSDSNEYNQFYDPLISHCLYIIVLSIRTFMESKSQDLSEEEQSKIHNLIQCTILNNFESISTSTNDFNNCISCLFKPFRLLYNDHSIQTNLFFLIIDLSFHIEKLKVFSDKKDLISKFFTYLHDFDSNVSELFTQKNFDISSLLSQQNEINHNIRRKIAQEKQEEIRRKMELQQKQFMQSNQLLLEEDDDEDYADHDGGPTNTTKIGNLQVKDLVCVVCKNNHETPNNPICSIGVTEYSSVKRMSENQSSHDPLPKSKKDLDNRKNSILNTNAYKLPTTDIDDNLIQIIYGTGTFTQTCSHYIHHSCLTQYSANPFDGFKCPLCNRYSNLALPVNQAKPITDDDSYNITTLPPIRDVLATLFTCYPNKETPSYLIDKTDSIYFLKFILNNIETLEIASRKNNNYLTIPTDPMKQSIDNSYHVYSKTEFQRQLDTLTLLYSNIIKITERRYNTYDFYKSELQSKYAQIDPFIIAILQHYVNRGTDPYQYILQAYTHLVADIISNKVSQNPLFNLLNQQDEIELILQPFIRKSYLFLHYCYISSKPIFEINFNFSNDEDIYTFTPITIESFSNIKELKRKLKLPSISEISNDNEFLIRMNRIMTPSSIKTFKYPLLHTLESKLPKFIDLPNDHITFLMDNITKSCSSNCDSLPRGVCLFCGHVVCFGNCCPGEFKNHINNCSSHGIFLGICTPEISLSLRNFDRDSSLSIYYDKFNEPALKSKPNLHLDLDSTKNIYIQWLKGLIHQRQN
The following text describes a protein:
Function:
Involved in the degradation of serine via 3-hydroxypyruvate. Catalyzes the ATP-dependent phosphorylation of D-glycerate to 2-phosphoglycerate.
Sequence:
MFDPESLKKLAIEIVKKSIEAVFPDRAVKETLPKLNLDRVILVAVGKAAWRMAKAAYEVLGKKIRKGVVVTKYGHSEGPIDDFEIYEAGHPVPDENTIKTTRRVLELVDQLNENDTVLFLLSGGGSSLFELPLEGVSLEEIQKLTSALLKSGASIEEINTVRKHLSQVKGGRFAERVFPAKVVALVLSDVLGDRLDVIASGPAWPDSSTSEDALKVLEKYGIETSESVKRAILQETPKHLSNVEIHLIGNVQKVCDEAKSLAKEKGFNAEIITTSLDCEAREAGRFIASIMKEVKFKDRPLKKPAALIFGGETVVHVKGNGIGGRNQELALSAAIALEGIEGVILCSAGTDGTDGPTDAAGGIVDGSTAKTLKAMGEDPYQYLKNNDSYNALKKSGALLITGPTGTNVNDLIIGLIV
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase. Mediates 'Lys-63'-linked polyubiquitination of the innate immune receptor RIGI, this linkage doesn't lead to proteasomal degradation but seems to enhance IFN induction.
Subcellular Localization:
Cytoplasm.
Sequence:
MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHFKQEEKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFFWLSPLASLVIPPVTDRK
The following text describes a protein:
Function:
In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.
Sequence:
MNTVFFIMTTLSSKPLILIDGSSYLFRAYYALPPLTNRKGQPTGAMYGVINMLRKLMVEYQPDYVAVVFDPKGKTFRHDLYHTYKANRIEMPNELRSQIKPLFEIIRALGFPLIIKEGYEADDVIATLAKKAKEKGMPVLVSTGDKDLAQIVNEHVTLVNTMTDRLLNSKGVLEKFGVPPEKIIDYLTLTGDTTDNIPGVPKVGPKTAVKWLSQYDSVENLIKHANEIKGKVGENLRACIDDLPLMRRLVTVISDLPLEENPTDLIQTEKNREKLIELFTEYEFKSWLAELLANQDKKVAAFQYATITDKKTFEKWMKKLADAKVFAFDTETTDFNAIQAKLVGVSFAVSPHEAAYVPLGHDYTGAPAQLDKEEVLRELKPLLEDPNKTIICQNLKYDAEVLAKEGLTIRAKTYDTLLASYVLNSSSTRHDLNTLALKYLGRIMVKFEDVAGKGVKQISFNHVTLDKATAYAAEDADVTLQLHHKLMPLIEKEKNLKKVFEQIEMPLVPILMKMEMRGVLVDTAMLQAQSIELGGRIALLEQQAYKLAGREFNLSSPKQLQTILYEELKLPIFKKTPGGQPSTAENVLQDLALDYPLPKVILEHRSLTKLKTTYTDRLPVQVHPASRRIHTSYNQTVTSTGRLSSNNPNLQNIPIRTEEGRKIRRAFIAPPGFQMVAADYSQVELRIIAHISKDPSLIKAFDKEWDIHRATAAEVFGVNLEQVTPEQRRRAKAINFGLLYGMSSFGLGRQLGIGRDLAKEYIDIYFKRYPKVHEYMQKIRIVAFTQGYVETLFGRRVYLPDIHASNMQRRRAAERAAINAPMQGTAADIIKIAMIKVSDWLQKNPVEAHLIMQVHDELVFEVAEKDLEKVIPQIKKAMEEAVALSVPLVVDVGVGGNWDEAH
The following text describes a protein:
Function:
Co-chaperone that binds to the molecular chaperone Hsp70 (SSA1 and SSA2). Regulates Hsp70 ATPase activity (By similarity). Required for recovery from heat shock.
Miscellaneous:
MISCELLANEOUS: Present with 9424 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MSASKEEIAALIVNYFSSIVEKKEISEDGADSLNVAMDCISEAFGFEREAVSGILGKSEFKGQHLADILNSASRVPESNKKDDAENVEINIPEDDAETKAKAEDLKMQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKKVLDIEGDNATEAMKRDYESAKKKVEQSLNLEKTVPEQSRDADVDASQGASAGGLPDLGSLLGGGLGGLMNNPQLMQAAQKMMSNPGAMQNIQKMMQDPSIRQMAEGFASGGGTPNLSDLMNNPALRNMAGNLFGGAGAQSTDETPDNENKQ
The following text describes a protein:
Function:
Major thyroid hormone transport protein in serum.
Subcellular Localization:
Secreted.
Sequence:
MNNDFAFHLYKRLIESPDYQSKNIFFSPFSVSMALSELSLGAGGDTKQQLLSGIGYNSTIFSTEEMHQLFHNLLEDIGNRTGVDIDVGTALYASDQFKPHSKFLEDMKEFYHSDGFTVDFRVKETVDQINKYVEEKTHGKINKAVDDLEEDTFMVLLTYIYFKGKWDKPFNPETTSESTFHIDDKTTVPVQMMHQYERLKVYYDAELSTKVLCLDYNDSFSMFLAVPDVHMGRKTIKDLEMTVSRQHVEKWRRSVSERKVDIYVPKLSLKTSYSLKDILKGMGMADMFSIKADFTGVSEENIYVSKVLHKATLDIDEKGTTAAAVTTVYSRVMSYSPMSDLRFNRPFMIFITDQTNDNILFFGKVVNPNEKL
The following text describes a protein:
Function:
Enzyme involved in the ethylene biosynthesis.
Sequence:
MAIPVIDFSKLNGEEREKTLSEIARACEEWGFFQLVNHGIPLELLNKVKKLSSDCYKTEREEAFKTSNPVKLLNELVQKNSGEKLENVDWEDVFTLLDHNQNEWPSNIKETMGEYREEVRKLASKMMEVMDENLGLPKGYIKKAFNEGMEDGEETAFFGTKVSHYPPCPHPELVNGLRAHTDAGGVVLLFQDDEYDGLQVLKDGEWIDVQPLPNAIVINTGDQIEVLSNGRYKSAWHRVLAREEGNRRSIASFYNPSYKAAIGPAAVAEEEGSEKKYPKFVFGDYMDVYANQKFMPKEPRFLAVKSL
The following text describes a protein:
Function:
Required for normal plastid function and plant development. Required for correct plastid ribosome assembly. Required for processing and maturation of 4.5S rRNA.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MSLASIPSSSPVASPYFRCRTYIFSFSSSPLCLYFPRGDSTSLRPRVRALRTESDGAKIGNSESYGSELLRRPRIASEESSEEEEEEEEENSEGDEFVDWEDKILEVTVPLVGFVRMILHSGKYANRDRLSPEHERTIIEMLLPYHPECEKKIGCGIDYIMVGHHPDFESSRCMFIVRKDGEVVDFSYWKCIKGLIKKKYPLYADSFILRHFRKRRQNR
The following text describes a protein:
Function:
Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
Sequence:
MIQKAICVMTDSVDQDQSNLDLSHGHHATVDLVLTAGGTGFGVRDVTPEAVRGILLKEASGLATAMLVSSLAITNMAALSRPICGIRNRSIIITLPGSPKGAIENLTAIIKTLPHAIDLARGEPSAGETVHTAMHGGHQIATHDINESNLAEKVDPIRHDHFKHHNCSRFDHLTPHAQTCSKDLKSNIINQPVTHRARISPFEMIPFETALDLVLNNASSAANMNKQLVMTRPVNTDSIGYVLAEDVMANENVPMYRASIVDGYAVMAADGPGEYPVIGSTTASQTTLSGSGLTPLKRGTVSRITTGAEIPPNADAVVMVECTELISMTEDSKEEKIVKLLQGVQIGQDIREIGSDIIKGSCILSKGCRIMCGELGVLTSCGIQHIKVYRRPVVSIMSSGNELIDAEADGTEKAAGYVRDSNRPTLHALLKHHGFDVVDLGIACDTHDGLATCLRQGMDQSDVIVSTGGVSMGEMDLLKPILERDLGAEVLFGRVALKPGKPTTFAVLDVPQSTRTCSSRRLFFALPGNPVSTMVTFYLFVLPALRKMAGYASPNLPRIKVKLGHDIHLDPRPEFFRAKLEHSEGMFTAFGTGIQRSSRMQSMTCANALLVLPALSDFIAASASNTDGNIKAGSVVEAIIIGDFE