lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MAAQSLRPCYAIANQSHRRQQQQSVHSRAQPSSSMAGGRWMQVALVALVVAVALHHHGVGASPNATVANGSVNGKLSERHSYNASASDDLITPDEINAGLLEYFAGPLPLAAMEAAKPKRANARPAAIYMNEFAVYIPRGADVADSIAHKYGFSNMGQIGPLKGYYLFHHNHVRKRSVDRSEAHHNALNTEPEVRWVQQQHEKPRFKRDYSTFDQDFVRFPGFRSLVSGTRMAYRDTSTHNIFPDPLFKEQWYLNGGAKDGPDMNVGPAWQKGYTGKGVVVSILDDGIQRNHPDLALNYDPAASYDINGNDSDPMPRDNGDNKHGTRCAGEVAAVAFNQYCGVGVAYNASIGGVRMLDGTVNDAVEAKALGLYPDHIDIYSASWGPEDDGSTVDGPGPLARRAFIFGVTSGRQGKGSIFIWASGNGGRYTDSCNCDGYTNSIFTLSISSATQGGYKPWYLEECSSTLATTYSSGTPGHDKSVATVDMDGSLRPDRICTVEHTGTSASAPLAAGIAALALEANPALTWRDMQYLVVLTSRSDPLEKEPGWILNGVKRKVSHKFGYGLMDAGAMVSLAEQWTTVPSQHICKSREINEDRPIEVSVGYTLQTHMDVNGCAGTVNEVRFLEHVQCKITLRFFPRGNLRILLTSPMGTTSTLLFERPRDITKSNFDDWPFLSVHFWGERAEGRWTLQILNGGPRRVSQPGILSKWQLIFYGTQTNPIRLKSEGTRTAGSAGYSGLNPFVFPTETDLNQQAGALGGAGAGYYQSADLYSNFMNYPNLFSGAGSGIDKTVATLNGHNIPTAQRENVMADSNNKLVVLHDCDPECDQQGCYGKGPTQCVACKHYRLDNTCVSRCPPRSFPNQGGVCWPCHESCETCAGAGQDSCLTCAPAHLYVTDLAVCLQVCPEGYYENYDNRTCVPCEANCASCQDRPDYCTSCDHHLVMHEHRCYAACPKNTYETEDYNCGVLPWENWIDCFDCFREEWLAGGGAITNLECPVWPSEYFENGHCHPCHSTCETCTGPTENECLTCASNLLLQGARCVNVCDEGYYMEVGVCAKCLHTCTQCVSRMNCTACMKGLQLQSGECRTTCADGYYSDRGTCAKCYLSCHTCSGPRRNQCVQCPEGWQLAGGECFPECPEGFFKTKFGCQRCHHYCKTCNGAGPLACTTCPAHSMLQNGLCIDCLASQYYDPPTQTCKTCHESCRTCSGPGQFSCLTCPFPLHLDRLNHQCVPCCAADASPDDQSCCHCDKATGGCINASPAGKRRIGAEQQLLQFGEESGAPAVPGDGGATTPGQAAGRAWQQFLTSTSTPTLMVVAVSGCLLIVTLFVVIFTVLQKRSQTMYTGIKYNKLGKKAASGRTTRISIPADGDDLLEPIVNNDEDEEEEEQNDDDDDDDEDESGQSGADGGEEERHQRRGGGGGRGARSDSRRSTAAMATAARGKRTFRYAPTAHRT
The following text describes a protein:
Function:
Removes the formyl group from the N-terminal Met of newly synthesized proteins.
Sequence:
MPVRTIIRKIMKGGSPEVLKAGHPFLRTKAEAVSLNDINTPAFLKIVKSMNAVFDSPLHSVLGLAAAQISHPVQLIAYQITDTQLIKEKNLPGPVARTFIVNPVMTILDKLPSAKWKAEYEFCESIPNYSGLVRRADHVHVTGFGLDGNSITVNAKGILARIIQHEMDHMEGILFIDKMERQSLRHDNYIDQFEMFKR
The following text describes a protein:
Function:
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
Sequence:
MTKRQKEVLDFITGFVQRNGYSPSFEEIARGLNLKSLATVHKHITNLQNKGLLARAHNRSRSLDVLPPRSRGRSVDRLPLMGRIAAGRPVEAAENAESISLGDIIGNREVFALQVHGESMRDEHIVDGDYVLVERTNTARQGEIIVALVRGAETTLKRFYLEGSMVRLQPSNAEMNPIIVPAAQVAIQGRVLGMLRKY
The following text describes a protein:
Function:
Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MEGRYNPFEDPDTIPVYQIFLLFITFVGPPTFLFVLFVRRTATRPHLHHTATVLVLGDIGRSPRMMYHSESLARHNWRTFMVGYAETPPTSALLENPMVHLLGLKEPPKMVGLLPWILRAPIRIIYQVFSVIHTCIWRVPCNTEILLVQNPPSIPTLALAQFICLATKTKLIIDWHNTGYSILGLRVGEGSRLVRIAKWFESTFGQTAYAHLFVTKALQEFLIREWDLKGRTSVLHDRPPTHFHRTVPMIQHELFSRLLPELKPSLPPSHLDTNDPTHTAFTEISSEGLAVLKHTRPALIISSTSWTADEDFSLLITALDLYQSAVDSGSALPKLVVLITGKGALRAPFENIVKSREISKWKDITVRCVFVPAQEYPPLLGCADLGVSLHTSSSGKDLPMKVVDMFGCGVPVLAKDFQCISELVKDGENGKVFGTGEELGEQMIDILSSFPSSEKLDDLKGYFDRMNTPRRRATLPTADVGEDEWSNWDDNWDNVVYNGILNKIRR
The following text describes a protein:
Function:
Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
Subcellular Localization:
Membrane; Single-pass type II membrane protein. Secreted.
Sequence:
MEGYAMTPEDMERGPVYNTTVTAVAEGKASRGWLWRLCGVLLIAGLCAAAALLFAWCQHGRPSTMQDEIEPQLEILIGAKDTHHTLKQIAGNAKAAIHLEGEYNPNLSADTVQWRKDDGQAFSQGGFELQGNQILIPHTGLFFVYSQASFRVKCNSPGEHTTPLSHIIWRYSDSIGVNANLLSGVRSVCQQNYGDAESKIGEGWYNAVYLGAVFQLNEGDKLWTETNRLTDVEPEQGKNFFGVFAL
The following text describes a protein:
Function:
Together with NOC2, probably involved in pre-ribosome export from the nucleus to the cytoplasm. Required for coordinated cell cycle progression during female gametophyte and pollen development.
Subcellular Localization:
Nucleus. Nucleus, nucleolus.
Sequence:
MSKIKPLSKSSQDLSLLTSDIASFASSIGLASALPSSGFNDTDFRKPAKSKTQKRKKPKKDQQHKDEDEEGEPKSNIGNEKGKDFGARKQNKDAPVKQTLQPKPKPGFLSIDDESTGYKKKRFDEFKSLPKLPLVKASLLSSEWYNDAAEFEEKVFGGRKVAVANKEDFKGVVEKKRELGERLMWQYAEDFATSKGKGGDMKMVISAQKSGTVADKITAFEIMVGENPIANMRSLDALLGMVTSKVGKRFAFKGLKALSEILIRLLPDRKLKSLLQRPLNIIPENKDGYSLLLFWYWEDCLKQRYERFVTALDESSKDMLPELKDKALKTIYFMLTSKSEQERKLLVSLVNKLGDPQNKSASNADYHLTNLLADHPNMKAVVIDEVDSFLFRPHLGLRAKYHAVNFLSQIRLSHKGEDPKVAKRLIDVYFALFKVLTTEANRKQGADDKGAADKKKSNPKDTKQEVSTDSPIELDSRILSALLTGVNRAFPYVSTDEADDIIESQTPVLFKLVHSANFNVGVQSLMLLDKISSKNKIVSDRFYRALYSKLLLPSAMNSSKAEMFIGLLLRAMKNDINIKRVAAFSKRVLQVALQQPPQYACGCLFLLSEVLKSRPPLWKMVVQRESVEEEEDIEHFEDVIEGDDVDPNKKAENDENVVEVDHDGVEKSSRDGDSSSDDEEALAIRLSDEEDDNASDDSEELIRNETPQLEEVMEVSNDMEKRSQPPMRPSSLPGGYDPRHREPSYCNADRASWWELGVLSKHAHPSVATMAGTLLSGTNIVYNGNPLNDLSLTAFLDKFMEKKPKQNTWHGGSQIEPSKKLDMSNRVIGAEILSLAEGDVAPEDLVFHKFYVNKMTSTKQSKKKKKKKLPEEEAAEELYDVNDGDGGENYDSDVEFEAGDESDNEEIENMLDDVDDNAVEEEGGEYDYDDLDGVAGEDDEELVADVSDAEMDTDMDMDLIDDEDDNNVDDDGTGDGGDDDSDGDDGRSKKKKKEKRKRKSPFASLEEYKHLIDQDEKEDSKTKRKATSEPTKKKKKKKSKASE
The following text describes a protein:
Function:
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
Subcellular Localization:
Mitochondrion. Plastid, chloroplast.
Sequence:
MASVTTVSGVTHACVSLCSAQAHSNVSARQRIPKPAALSKCQLLRPCRPSVKLLSGVRLSSGSPFSRSGRSFTTSVSATVAEGETVVEEATAEDEIVAEEDADAAPEPAAPDAEGGEAKPAARRPFKNRRKITVKIEDLQPGQTVPGKVRSIQSYGCFVDIGAFTDGLIHISELADQFVENVGDLVEAGQEVQARILEVDVAKGRISLSMRTPREERPEPAEGAGAPRAERGAGPRPQRGGDQRPRRAVAGGRGGSDKPSHGIRKGQKFEGTVTSIAPFGAFLELKDGVEGLLHASEIGEGSERVEVAEHLEMGQKVNVTVLSVTKDRISLTTKERVDTDDINVKLNQGAEFGTDGITNPFEAAFKKSNLVLDKLPGAEELAKTKKPEPVAAASDEIKTETQEIQKAGLFSGKKVDDAPAPAAEKPEEADADDSSNAGAAEAVQETVEDVVDDAKDAAQAVTEGVEPIADEVADVAKPVVEKAEEVAEPVAEKVEEVVEPVAEKVEEVVEPAAEKVKEAAEPVIEKVEEVVEPVAEKVEEAAEPVIEKVEEVVEPVAEKVKEAAEPVIEKVEEVVEPVAEKVEEVAEPVIEKVKEVAEPVIEKVEEVAEPVAEKVEPIVEEVKETVTNAADTVGEKAEPLVENAKETVTEAVEPVAEKVEPAVEEAKETVTGASDNVGDQLGAIQTGGIGDVVGPVAEAVENVVDSVKEAAEPVVEKVEEVIESVKDAVAPAAEETKEAAPAVEAAKEDAPSLAEQVKEAADAGVAAVTGVVDQVTSATEEAPAAKEEKPKEAGGISAVLVKALREETGSGMMDCKKALAEANGDIDQARDILRKKGLASADKKSARVAAEGAIGSYIHDSRIGVLLELNCETDFVSRGDTFKELLEDLAMQVAACPQVEFVSVDEVPADVVAKEREIEAGKEDLASKPEAIREKMVDGRINKRLGELALLEQPFIKDDKLKVKDLIKATVAKIGENIQIRRFERYNLGEGLTKKTSNLAAEVAEQTQKKEAAPAPAPAAEEKKEEAPAEAKPAVAVSASAVKELRAETGAGMMDCKKALAECDNDVEKARELLRKKGLASAEKKSSRLAAEGAIGSYIHDGRIGVLVEVNCETDFVARGDKFKELLEDVAMQVAACPQVTVVSPDDVPAEIVAKEREIELGKEDLASKPEAIREKIVDGRMAKRVNELALLEQPYIRDDKQKLRDVIQAAVATIGENIQVRRFVRFNLGEGIEKKSVDFAAEVAAQTGKA
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MGAESAGRETAPWAVKAFSPPSDVLAKLWAARNELCQSLEKTRALGNQLNEANKRLQMFQDRLSPVRRSLLPLQEKSKITESLTQRINKTLEPAMQVLKMFDVVSKIRVRLVKEPRDDFDGYLAALIQLEEAVDYLKHNSIVAINWLQEAVAYLNYTGSTDTVRLRRLNESLATLQSQQAGGAHELDGGLLVTALGKLEKEFKRLISEHSQPIELPEQMAPRESNSPPSSELDYLVSYPPQVLQKLQTIIEKLAGNVHYQRCVDAYQDTRLVLCEESLKALDVRYMNNVTPKTVNSIPWDDLQNMVEKWAQQLEVIVKMLYTGERRLARQVFKNVGQAVWVEILYDLAEPEMDTFLRFGESVAASERSPEKLCKLLEMYESMEKCEHSVIQVFDGQACGEIRSRYRELLKQIVYAAGKTFWDIDDWIKEQKEGVSLDGRVMQLCSWVVNYLGYVIALFPITLSKVLRIAQSWEGEGAEDKGLPEGLALILNTLEGLVETRAKEFHDPALRHIFLMNNMYYIRNRVKNNALGPLLGEDWISEVGRKVSTNALKYQREAWQQVLQHLNSDGLKGSSSSKSGSRDLVRQKLRAFNAAFDETVQIQSKWLIAEKDLRDGTLAAVTQMVVPAYRSFLGHFGSLLEGRGRDSDKYIKYTPEILETILGDLFGGNNA
The following text describes a protein:
Function:
Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MQGNLPPEAQEKLEQLQDLQEKAQNVATQKQQAEQQLSEAETALDALGDIEESTTMYREVGELLVETEYDNAHDDLDEKVSDLEVRVETLQKQEDRVQEQFESLQEELQDMLGGAGGAMGGGPGA
The following text describes a protein:
Function:
Essential for proper capsid assembly. In absence of Gp31 the major capsid protein (Gp23) assembles into 'lumps'. Acts as a co-chaperonin with the host groEL protein.
Sequence:
MSEVQQLPIRAVGEYVILVSEPAQAGDEEVTESGLIIGKRVQGEVPELCVVHSVGPDVPEGFCEVGDLTSLPVGQIRNVPHPFVALGLKQPKEIKQKFVTCHYKAIPCLYK
The following text describes a protein:
Function:
Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
Subcellular Localization:
Endoplasmic reticulum membrane.
Sequence:
MVRSSKFSQEATLKRGESRENPTDLRSKLTNIYTIEMRDVRFAMSIRPRLRIVGVLILAAWIGLVALFGLLKPIKNGCTMTYMYPTYIPISVTDDTTPGRYGLYLYHEGWRKIDFKEHLKKLSGVPVLFIPGNAGSYKQVRSVAAESDRAFQGGPFERTFYQEASLLRGGGADTESVDYDLPSQYSNRLDWFAVDLEGEHSAMDGRILEEHTEYVVYAIHRILDQYKESHDTREREGAAASSKLPHDVILVGHSMGGFVARAAAVHPRLRKSAVQTILTLSSPHQSPPLALQPSLGHYFAQVNREWKKGYEVQTSPGGNYVSDPLLSGVVVVSISGGYNDYQVRSKLESLDGIVPSSHGFMISSTSMTNVWLSMEHQAILWCNQLVVQVSHTLLSMVDSKTNQPFSDTDKRLWVLTRMLQSALAQSFNGMTPMEVSHELPILASKGSTCFLDWRDDALDRDLYIQTSTVTILAMDGRRRWLDIDLLGSNGKNHFIFVTNLVPCSGVRLHLWPEKEKSNSNLPVCERVLEVTSKMVLIPAGPAPKQSEPGSQTEQAPPSAVLKLGPEDMRGFRFLTISVAPREAVSGKPPVAVSMAVGQFFNPGDGAVEVSSQSMLLSTYWAKEIFLKEDHPLAYNLSFSTSLGLLPATLSLKTTGCGIKTFGLPDGETGDLDKDKLCKLRCFPPVALAWDSASGLHVFANLYSETIVIDSSPALWSSQSSEKTTVMLLVDPHCSYTASVHVSAPAMSSRFVLLYGPQIVGFSFAVIMFALMRQANQWDNKLSVPPLLSAVEYNLEMPSPFLLLAVLPLISSLFYSFLMGQPIPPLTSFTVVSLICYLLANAFISVLTIVSKFPFQASALVHTTVKSRCQALERNYSLAFLHWFSILSSSFFCLKAIRILKLNTTILMTLIAVTLVSFVHPALGLFVLLASHALCCHNSMCCIMMASKRKESLDQKNEAERKTRHPSSREDPVSGDLSEKSFVETQADIFNHRHGLLILHLLAALMFVPSLAAWFQRIGTGQSFPWFADSALCVGVIFHGILNSRPESSILRSFPFFSGHQIRPHHIYLLAGYYCFFSGLELAPYKVFYAIASLGYISLTLKISQVNKNDLRFRTKSRIHRN
The following text describes a protein:
Function:
Mitochondrial co-chaperone which forms a complex with prohibitins to regulate cardiolipin remodeling. May be a component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Sequence:
MASTVVAVGLTIAAAGFAGRYVLQAMKHVEPQVKQVFQSLPKSAFSGGYYRGGFEPKMTKREAALILGVSPTANKGKIRDAHRRIMLLNHPDKGPLVEEGLKPIPICRSCSSICRRSILSCSTSYNQNKDCFIHCVCLCAFMNAPMGTPVRHCETHLTHLPQPTSSTGLTCFGLELEL
The following text describes a protein:
Function:
Sterol O-acyltransferase that catalyzes the formation of stery esters.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MARSKNKSQPESTNIKDLQSPQSTSQSSHQSLKAGQQGLLYRAVTSQREPLIPTANDDAVLADSTCLASDAVAPGEPSDAPKTRYSHTFRIHNSIRASPLSKESLEQNFRGFFNLSMLLLGVSNLRLIVENFQKYGWLLNLPSSGFSLTDVHMAILSIIFQIFNVLVAFSAEKCAAHYQENTYVLWFIQAVHAANISATIIVPTWISWSFIWHPVTSSIPLFLATTLFLKLISYALVNADLRHDVSKDKSKTAEDMVSLKHQPLTGGHSQNVDANIIPYPENINLDNMLYFIVAPTLCYQQVYPRTKRIRKMFLFKRFVELSTSLAGMFFLTMQYAAPTLRNSIEALENMDMLRLLERMLKLSVVSVVIWLLMFWSFFHCWLNILAELTCFGDRRFYQPWWNARDISEYWRLWNSPVYNWGKRHIYLPLILNLGFHPYVALAVVFCISALLHELLVAVPTHCLNGVAFLGMMGQVPLIFIVGAIFTTCRKVLGRPKNDALFDTIGNYVFWITFTIVGQPACILVYYTQWFKANNR
The following text describes a protein:
Function:
TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription. Required for the expression of a subset of ethylene-responsive genes. Probably involved in the negative regulation of cytokinin sensitivity.
Subcellular Localization:
Nucleus.
Sequence:
MAEPIPSSSLSPKSLQSPNPMEPSPASSTPLPSSSSQQQQLMTAPISNSVNSAASPAMTVTTTEGIVIQNNSQPNISSPNPTSSNPPIGAQIPSPSPLSHPSSSLDQQTQTQQLVQQTQQLPQQQQQIMQQISSSPIPQLSPQQQQILQQQHMTSQQIPMSSYQIAQSLQRSPSLSRLSQIQQQQQQQHQGQYGNVLRQQAGLYGTMNFGGSGSVQQSQQNQQMVNPNMSRAGLVGQSGHLPMLNGAAGAAQMNIQPQLLAASPRQKSGMVQGSQFHPGSSGQQLQGMQAMGMMGSLNLTSQMRGNPALYAQQRINPGQMRQQLSQQNALTSPQVQNLQRTSSLAFMNPQLSGLAQNGQAGMMQNSLSQQQWLKQMSGITSPNSFRLQPSQRQALLLQQQQQQQQQLSSPQLHQSSMSLNQQQISQIIQQQQQQSQLGQSQMNQSHSQQQLQQMQQQLQQQPQQQMQQQQQQQQQMQINQQQPSPRMLSHAGQKSVSLTGSQPEATQSGTTTPGGSSSQGTEATNQLLGKRKIQDLVSQVDVHAKLDPDVEDLLLEVADDFIDSVTSFACSLAKHRKSSVLEPKDILLHLEKNLHLTIPGFSSEDKRQTKTVPTDLHKKRLAMVRALLESSKPETNASNSKETMRQAMVNPNGPNHLLRPSQSSEQLVSQTSGPHILQHMTRY
The following text describes a protein:
Function:
Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.
Sequence:
MLEKLNSCGDDFIPSYLHPLFGANNDAEMFSQMVWISFFYTLSVALSMALFPAPYGRYSSSKYGFLLPAKIAWITQESPSFIMPVILLLTTSSAFWNSTVNKMLLIGFIIHYVNRSIIFPLCARGNEDTPFIPYISAMAFSIFNGFMQGHYLLNYYLYDEQWLTSPQFIIGFTMFCVGMAINIHSDQQLIHLRKPGETGYKMPVGGLFEYVTAPNFFAEIIEWTGFAIASCSPPAAVFAFFSTVFLCYRAWHHHHFYLKKFDNYPRSRKIIIPFVF
The following text describes a protein:
Function:
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
Domain:
Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
Sequence:
MSFLEWMSPAFVLVEFVANDILIRPFDRSVRLSPSTDFDVKERVRAATDIVDVIGHDLELRPQGRHFVARCPFHNDTRPSMTVNQERQSWKCWVCDIGGDIFSFVMQREGVDFPTALRSLAERAGIEIPEFNRGPKTQPGSPDDKATLMKAVDLICRAYFDELACGKSDDAKLARDYLASRGIDDSNRELFKIGFAPDSWDFAVNLLKRNKFSEAVAQAAGVAIGRDGKSGCYDRFRGRLMFPIDNAQGQAISLGGRIIPAIANRIAEAKGDGSNGGAKYINGPETMLFRKSNELYGLHLARDAMRAADEVLVMEGYTDVVATRMAGIDHSVAVLGTALTASHVRVLKRFVNRVVLVLDGDDAGKRRAEEVLELFVTADADLRILTLPDGLDPADFLAQQSAANLLDMAGKAPDAMDHKLNRLTEGVDVTRDTHRVTTAIETMLGVLTKTPTKSDKTELKIDQLLVRMSQTFGLPVERLQRRLETVREETAERERKQARYRKANTSGGHQDSAQTSAPASQKPASRPPSSASMDDFDPFEQAAMEDAAAFGIDEGFDDYAPSTPSDFGAANHPRRNSPSGPTRPQPPEQGAAITGVDRELFEILIESPEVAAMAVEAIDPSWLHSNTAKMLLSAYQDLDLQGRDLDVDSVLVLLENDFLKNQIITLQERIEQRAGHVLDEPHLRYTAILTRFREREFDAEKTRQIEKLQSASLPEDEELAMLEQLFAAERIRQTPR
The following text describes a protein:
Function:
Vacuolar cation/proton exchanger (CAX). Translocates Ca(2+) and other metal ions into vacuoles using the proton gradient formed by H(+)-ATPase and H(+)-pyrophosphatase.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Sequence:
MAPPESSHHHLLESGLLEVSKAPSAAVAAEEEEKKEAAAWTPSSSSSMTGRKIKSEASPLLRRLLGGPAAQLQEVLLGTKLYPLFSAVPLAVAAESLRLGRVWVFAFSLIGLAPLAERVSFLSEHIANTVGPTAGGIMNATCGNVPELIIALFALHKNKMEILKWSLLGSILSNLLLVLGSSLLFGGIVNIGKERPLDKRQADVSIGLLLLGVLCHIATLVSKYTSSTGDSINSSSVMQLSRSCAIVMLIAYFGSLMFQLKTHRQIFELEEDSSDSSSSEDDATDKSVIGFASAMVWLIGMAVVTAMLSSYVVTTIEEASESMGIPVRFISIILLPIVGNAAEHAGAIIFAFKNKIDISLGITLGSATQISMLVVPVILIVSWVNAIPMDLDFNLLETGSLAMAVITTAFTLQDDKWHYLKGLNLVFSYIVIAVCFFVMKALPTLKKEDD
The following text describes a protein:
Function:
Involved in formation and maintenance of cell shape. Regulates protease expression and stimulates the neutral protease production in Bacilli together with MreD.
Sequence:
MPNKRLMLLLLCIIILVAMIGFSLKGGRNTTWPEKVIGDTTGVFQNIFHTPAEFFAGIFENINDLKNTYKENERLREKLDGQTQYEAKLQELEEENKSLRDELGHVKSIKDYKPILATVIARSPDNWAKQVTINKGTQQNVAKDMAVTNEKGALIGKIKSSGLNNFTSAVQLLSDTDRNNRVATKISGKKGSKGYGLIEGYDKEKKRLKMTIIERKDKQDVKKGDLIETSGTGGVFPEGLTIGEVTDIESDSYGLTKVAYVKPAADLTDLNNVIVVNRDVPTVDTEEEGS
The following text describes a protein:
Function:
Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MNLEGSGRGGEFGMSSVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQDYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISDPYKVYRIVPEGAKKGAKQLTLEDPQMPMSHPYGMPAPYTSLPAQVHNYMIPPHDRGWREFVPDQPHPEIPYQCPVTFGPRSHHWQGPACENDCRLHICLYYREILVKELTTSSPEGCRISHGHTYDASSLDQVVFPYPEDSGQRKNIEKLLSHLERGVVLWMAPDGLYAKRLCQSRIYWDGPLALCSDRPNKLEREQTCKLFDTQQFLSELQAFAHHGRPLPRFQVTLCFGEEFPDPQRQRKLITAHVEPLLARQLYYFAQQNSGHFLRGYDLPEHVGSPEDFHRSMRHSSIQE
The following text describes a protein:
Function:
Functions as an E3 ubiquitin ligase.
Sequence:
MRGRRGRGGARAPPGARPASRGSGSSPEATGEEEPLVRNVQEETMARKHHGQGSSSVIPESPSRFWPAAPEAAKNSAAPASAPRFWRGAPETGKYSSGPTSASGFWRGAPQGAKNSRSPSWSAGRSSHERSTVPDVAAASEAEPVPVVAAWTAGMGDEARSGLQRAAGEITALTKMKPPRGFATNCPHGDADPLHGGAMDNSVMLASACSIHQPYQQTLPSDEQIQDILKKISVLSELQKEAVHLQQTAKRVLSVTRNSSAPRILRHEQACSDVPSTSGSVPSIKQPYQEILFPCSTADNTLSSPLVPPSEEQIQDILEKFSGPLQIEDTLVRKETGTAILALCRDEEANPSAVDYDMPDTLLECPHGDSANQSYELWFNSRKNRCHPNEVPVKWSNEDDDGIPYPLYAEFCGDNSSLSPKREWDDVRVVRRLRGLRWQERAAARTHFREVRDSWRVAGRKPTSLFMSAMDKVRDERPKEYSGGRTIPEYLICPLSHELMLDPVTIATGKTFKQRFLKAWFEKSGHICPLTYETVSSTIIRNDRIRGYLEEWDEVLKEDKVTSHSSRRTRQ
The following text describes a protein:
Function:
SNARE required for targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Sequence:
MADVLNALEEKVVELQQSESVEVIKRHFREFRKIWETARVELEYSSIQLDSVLRYEKAVQEYIRLNRRYRNKIASGEPWLPIAQEIGKIVDEEEITSPSDGSLQKRSMDNSGSWQSDDIYLTSASQVTAAMRDIHAQMVQAVDMSAENAMELSSSTNLLETLQEKYFGVEDVLYTSKRIIKSLKLSDRSDYFLVVSGFGFFIFVVVYLLFKRIVWPILSMFLWFLR
The following text describes a protein:
Function:
Component of pre-mRNA cleavage complex II, which promotes transcription termination by RNA polymerase II.
Subcellular Localization:
Nucleus.
Sequence:
MDQAAANAEGRAKQIEKEYLSSLADLNVNSKPLINMLTILAEENLEYAQIIVHAVEKHLAKVAPDVKLPILYLVDSIVKNVGKQYQTLFSQVIVNMFCGVFQTVNEKIREKMFSLRQTWNDVFQQSKLYTLDVKINSIDPGWPITAQLKSKTPTAIHVNPMFLKANGPEPTIAMQQQLRDKQRELLELQARKLELELLTTKKRIMEQEKQLSIQTESVAKEPSLELVKSLDGAGGHLPVIPTIPPPGVMPKSRIAPVTMGMVNMVKTRDPRLAKQQAAAQLGGPPSTVTAGMNNHNAALGAMAIPPPAMASGLMEASHHGATSAKQSSALARDNFGAKNRRPEASGVESTRSESSTQGEGGSSSSARGKKHTPSSTASISSASSHRSRHDNDAKVRKDRKEHSSSSSSTSSSRSSTKGGSKTGSSARSGSNSGSDKRKQRTQSNSDGGSPHGRKSPHSPGKKKSSSSEKSSSSGHSQNDNSPKAAGKSRSESKSSSELHALSGKQPSAQLARNNNVESKKHQHPAGEAAAFEDRDVDLRYGVPQKRIKIDEPVADGLSVAKEADEMVVTMVGQKSSEVQNNSATDDEEALSAMIAKDIDLRAIPLQLLTPKLVPELESSLGGSKGDASGSRSSKMESPSKRSAELDDGDEFSSGKKRSSPINSDEPNAKKSKAEMIDALFGNEDVDLRQLPIGGTLLMGDDARDVDFPKMENAVNMPRSPLSEKTNSNHGAKGLEKDKLGRPLLYNKLPDDPIERRRSIVSLTKPGDIDHRFPQQSLHHHDAADEDDNSMDSMNANIKTIIAQAQDQMEKGEITPEQYNILMKQVIQLNETQKIRQAQRIEHVKRQDQSVIRIDDNGSMSGEDDVIVTSVTPATPGLSAMRLNDPKDSSSGIVNDFRGKIHPIDGKPPLVKPFEGAPFAGIGIPPTSVPPPDIRAQRDPRRIRESKWNRVEPGPGPAWANRPVGPIVGGPMVVAPPLGGGIRPGLAVPSPWEQAPFPVMADGMSRFPAPPGPLPLGVLGGLAPNMLNPALPKLNDSVRTINIDGIQREIRFYEEIAVIFMNWDEPKEIGFQKGARMVVVDDRETFELGFNEPYKSVSIENKVYQMRLGAPTRELYIDDSWYECYFGDQPTTIMLDGKPRVFKIAGPAPQVKIGDSRKDLVAGKINMIVDAKYMIPVFLDCKPQVFEVYGVMHRLQFADFLLTVLIDEQPFPVDYGGLPMVVRSRDRDYYIRFTALPNLVVPGRVYIRDMIRTPLYRDLRTPPKDPSALEPPVPLNPPFAPPTTAPPALPGAAGLGFGGINTLPPGAIGPQHPGLAGANATSTGLDYLTNLMPSMAMQTGAAAGKNGPGYRIEADEKAAAAAGVGASAAAGSAPGSAQQPNASAAVGGLLANINVEELYKKIVAAGIITKLGAGTSSSPTPPQAAGGEAGAGTSAGGKDGKEDASKSKDKDKAPIPEIEPVLLDKPETIKKRQAAVVHQLFSGMQCSSCGVRFPPEQTMKYSQHLDWHFRQNRRDRDSARKAHSRKWYYDVSDWIQYEEIEDLEEREKNWFETQQTDQGELKKGGAGGGMGLGGNDGDDFSSHDDAPQPSCPAGLDESDRQCHMCHDVFEHFYNEETEEWHLRNAILVDGSTYHPLCYEDYKASLTMTETTLGNGTLGASLDESQKTDEAMDTSGAAGEAGEDGEAADGAGKDKSKASKKDNGMEDDDDDDDVIVLPAVEPVVEEILDDDEQAAEKKEGDAEAAEQSSTVDEAKSVAGSAKSPRPEFQERQIDEDLFIQEPNIEVTDLDTIEDKPPGESGEGASNGGQDPSTLSSLLRVKIKQEPKEEDDADEEDALFEEVGTIESSLVEVAERSPAANNAAEEEPYEDVIAESIPSPSESSNQMGIVAQPKATIDGNVDLQDAPQSATVVPNKIKINITKGKAQQQQQQVAAASSNNDGEPGDGGSNGVNTNNFNEDSQGVEDEASNDGGGAGGSLEERDEKNGAEQSNNKESSTVATLPLAADAVAEVAFEETTDVAYELKEGLLGIELNRQPRVTSGLEASGLCSIM
The following text describes a protein:
Function:
Binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils).
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Golgi outpost. Cytoplasm, cytoskeleton, microtubule organizing center. Note=Golgi and microvilli on the cell surface. Localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation (By similarity).
Sequence:
MAVCGRVRGMFRLSAALPLLLLAAAGAQNGHGQGQGPGTNFGPFPGQGGGGSPAGQQPPQQPQLSQQQQQPPPQQQQQQQQQSLFAAGGLPARRGGAGPGGTGGGWKLAEEESCREDVTRVCPKHTWSNNLAVLECLQDVREPENEISSDCNHLLWNYKLNLTTDPKFESVAREVCKSTISEIKECAEEPVGKGYMVSCLVDHRGNITEYQCHQYITKMTAIIFSDYRLICGFMDDCKNDINLLKCGSIRLGEKDAHSQGEVVSCLEKGLVKEAEEKEPKIQVSELCKKAILRVAELSSDDFHLDRHLYFACRDDRERFCENTQAGEGRVYKCLFNHKFEESMSEKCREALTTRQKLIAQDYKVSYSLAKSCKSDLKKYRCNVENLPRSREARLSYLLMCLESAVHRGRQVSSECQGEMLDYRRMLMEDFSLSPEIILSCRGEIEHHCSGLHRKGRTLHCLMKVVRGEKGNLGMNCQQALQTLIQETDPGADYRIDRALNEACESVIQTACKHIRSGDPMILSCLMEHLYTEKMVEDCEHRLLELQYFISRDWKLDPVLYRKCQGDASRLCHTHGWNETSELMPPGAVFSCLYRHAYRTEEQGRRLSRECRAEVQRILHQRAMDVKLDPALQDKCLIDLGKWCSEKTETGQELECLQDHLDDLAVECRDIVGNLTELESEDIQIEALLMRACEPIIQNFCHDVADNQIDSGDLMECLIQNKHQKDMNEKCAIGVTHFQLVQMKDFRFSYKFKMACKEDVLKLCPNIKKKVDVVICLSTTVRNDTLQEAKEHRVSLKCRKQLRVEELEMTEDIRLEPDLYEACKSDIKNYCSTVQYGNAQIIECLKENKKQLSTRCHQKVFKLQETEMMDPELDYTLMRVCKQMIKRFCPEADSKTMLQCLKQNKNSELMDPKCKQMITKRQITQNTDYRLNPVLRKACKADIPKFCHGILTKAKDDSELEGQVISCLKLRYADQRLSSDCEDQIRIIIQESALDYRLDPQLQLHCSDEIANLCAEEAAAQEQTGQVEECLKVNLLKIKTELCKKEVLNMLKESKADIFVDPVLHTACALDIKHHCAAITPGRGRQMSCLMEALEDKRVRLQPECKKRLNDRIEMWSYAAKVAPADGFSDLAMQVMTSPSKNYILSVISGSICILFLIGLMCGRITKRVTRELKDR
The following text describes a protein:
Function:
Phospholipase that may play a role in phospholipids remodeling. May selectively cleave myristate (C14)-containing phosphatidylcholines through its predominant phospholipase 1 activity, cleaving preferentially acyl groups in sn1 position. In parallel, may have a minor phospholipase 2 activity acting on acyl groups in position sn2. In addition to (C14)-containing phosphatidylcholines, may also act on other medium-chain-containing and oxidatively truncated phospholipids.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MAEISDQLSTSVEKMWISKSSLAIFVGVSVATITYYLSHVVKKPVLITGSKSCADFLQHHCPVLVQEYYPTVWCFTSRAHTILCSVLSDLTRWKLPPYRREVLDMPDGGELHLDWLEHHGNSHYNNSHHDNRTHPIIVILPGMSGNSRSHYVINLARGASKKGYRSVVYNHRGSNGVKLKNNKYYCAADTSDLQHVVTHIRKLYPDAPLMAAGVSLGGMITFNYLAKFGKDCGLVAAMVMSMPWNTFKTTESLEEPLNRLLFNKYLTFGLTQYVRQNREVFDKDSRVDVDHALKSSTIAEYDKRFTIKVFGFESVDQFYTLASACYKVSKVQTPLLSLNAADDVFAPLSSIPTKEIEKNPNIALVVTSHGGHIGFGDWLFPSRESFMDKLYQQYVDAVFKYRQEEHVGTQKKREWENREESWVTKVDPDTKRNLEKERMVGKRVSKSPGGKWPCPVCARVCGSRIGLYSHQRIHENEKRKVLSIQF
The following text describes a protein:
Function:
Neuron-specific restriction factor that prevents herpes simplex virus 1 (HHV-1) infection in the brain by blocking viral entry. Also able to restrict herpes simplex virus 2 (HHV-2) infection, although to a lesser extent (By similarity). Acts by preventing the association between the viral glycoprotein D (gD) and its cell surface receptor NECTIN1, thereby inhibiting fusion of the virus and the cell membrane (By similarity). Also able to prevent the association between the viral glycoprotein B (gB) and MYH9/NMMHC-IIA and MYH10/NMMHC-IIB receptors (By similarity).
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MGAQAPLRLPAAPPLAVCGYTSVLLLFAFCLPGSRASNQPAGGGGDCPGGRGKSNCSELNLRESDIRVCDESSCKYGGVCKEDGDGLKCACQFQCHTNYIPVCGSNGDTYQNECFLRRAACKHQKDITVVARGPCYSDNGSGSGEGEEEGSGAGAHRKHSKCGPCKYKAECDEDAENVGCVCNIDCSGYSFNPVCASDGSSYNNPCFVREASCIKQEQIDIRHLGHCTDTDDVSLLGKKDDGLQYRPDVKDAGDEREDVYIGSHMPCPENLNGYCIHGKCEFIYSTQKASCRCESGYTGQHCEKTDFSILYVVPSRQKLTHVLIAAIIGAVQIAIIVAIVMCITRKCPKNNRGRRQKQNLGHFTSDTSSRMV