lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the deacetylation of N-acetylglucosamine (GlcNAc) residues in peptidoglycan, a modification that confers host lysozyme resistance and contributes to pneumococcal virulence.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQKSFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKDKLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQPFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDSQIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDDGPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILSQLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDWKSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNTRLKAHELYYSRDE
The following text describes a protein:
Function:
Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling. The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane. PEX12 also regulates PEX5 recycling by activating the E3 ubiquitin-protein ligase activity of PEX10. When PEX5 recycling is compromised, PEX12 stimulates PEX10-mediated polyubiquitination of PEX5, leading to its subsequent degradation.
Subcellular Localization:
Peroxisome membrane; Multi-pass membrane protein.
Sequence:
MLFQVGGQGARPTFFEMSAAQQLPASLRAALSYSFGVFALRRPSLHKVLDYEDEFFALLMSVLESHSLRTTDGSFSESLYGLRRRPVNVSVNRSSPGAESNVKVYDSALRKRQKTLSVIFLVVLPYFKSKLQSVYNKEREARLQASLWDQGEVRFDEAGFVSDQQGETSQAQVGTTAGEVSHLTRLRTNFAALIGVCYPWIHATHEGLSFAYQLLYLLDATAFYSPGLHVLGLHVCRATGQELMDSSSRISRIRSRELERLRGPPWLKTVQRVLLNCTYTTLDYAQTGLIAAVFFFKMMEWWYQSAEERMSAPTVYPPPPPPPLPKVAKDGLPLPTDRTLCPLCCQKRNNPSVLSVSGFVFCYSCIFKSVSQHKRCPVTLMPATVEQIRRLFHDL
The following text describes a protein:
Function:
Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Phosphorylates cofilin at 'Ser-3'. May play an important role in spermatogenesis (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MDRSKRNSIAGFPPRVERLEEFEGGGGGDGNTVQVGRVSSSSYRAIISAFSRLTSLDDFTREKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANLLKEMQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLDSDLYLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDENGYSAVVADFGLAEKIPDASIGREKLAVVGSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQNMVGDCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLKEIMSRLPEEELERDRKLQPTAKGPLEKVPGGKRLSSLDDKIPHKSPRPRRTIWLSRSQSDIFSHKPPRTVSVLDPYYQPRDGATHTPKVNPFSARQDLKGGKVKFFDLPSKSVISLVFDLDAPGPGSTTLADCQEPLAMSSRRWRSLPGSPEFLHQACPFMGCEESLSDGPPPRLSSLKYGVREIPPFRTSALSAASGHEAMDCSNPQEENGFGPRLKGTSLCTGAASEEMEVEEERPRRASVYFSISGISLQTQAKQDG
The following text describes a protein:
Function:
May play a role in RNA metabolism.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSSSKANQTRVCYQPEDTTFIIIASNGPDVMRWRKDKTVPLTEIVDSFQVFTTSNNKGNEGQLITASKQELENTFGTSKDVDVVTKILTDGKIIPHREHGKHKEVN
The following text describes a protein:
Function:
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Subcellular Localization:
Cytoplasm.
Sequence:
MTTDQAAERELQSSLLRISIICASSIQSLREPVQPTILPADNQSASPSTSLPPTAEKLSSQIVSDLTQLLVLVQKHTTNLALALKPSAKSTAAQASSALSPVSGLDAKSLEAAQAQIVSLGSDLLPKIIFIAKKAWKDRQVFQQRPKSDHSDPAQIAERHKLEQLANEMGGQLMSAEQLGLPPSQRDDLEKKLEYSLGNSFAREIRSAVEDVLGSMADLLHSLLDDRARKALEHASQARDRADGYIAGVNKKLNSLSVSANNDVADLRKRTLAANNLVWETCAKYVGERNADGTARTVTSVGPNGVRTKVHIKGLSKSNLEASKRSWNNRVDLMRDGLQELQQGIEAESHANADLNDDEPDEFSFPAATPLSAEQKDRLRQLSNLVKMGNLTHENILKEVAKSSAAQSSIDLDEVEELGKQIEEAQDELVAACLYGEADAGLEINMFDHDANEDEDLDIANGSVANDTDADADLTEEQAIQKAILRTFEQYVQAVVGLSAYVTDREELVDKVNIASASDEEGDFAHVFAAKFKQLSKVLSEASSGIALGTSTTSSPVSTDTRSLAVKHSPVVQANDDFRTDVFVSELQSIADKLGFGAKITDRAVAEHLDSVDPLRRMREGYILPKFKDVCNADYPSTSAETAADADSLYMCGNSLGPLSRLGKKYLEQEIEAWGRMAVLGHFEHPYGTPWTQMEKRVGELCADVVGAKASEVVVMGTLTGNLHSLLATFYRPATKPFGIDFAGDMDAAKKEGKRIKHKIIFEQKAFPSDQYALASVIELNGFKAETSMVPLVPKQGAKTLETADILATIEKCGKEGETAMVLIGGIQYFTGQLFELEKLAAKAHEYGILFGVDLAHAFANVPLALHDWGIDFACWCTYKYGSSGPGGIAGLFVHEKWHEAKLTRQAGWWGHEKETRFSMPDKFVPTRGAEGWQTSNPSMLDMASLKGSLETLLKATQYGERRPNDQGLTAQGKHGKGSIMPILRSKSLRLTAYLEALLLSPGFFPEGFDIRVVTPRDPLQRGSQLCIQIPDPSAATEEKAQEQQQQQDPSRADRKDVPPPIDGKRLIARAHKRAEKQHGLVADIRHPDMLRLAPLAQFSTFTDVWRTADVLRQSLLDEVKADMSA
The following text describes a protein:
Function:
Plays a role in transport between endoplasmic reticulum and Golgi.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MLSKLFRYDAFAKPTADATIKTASGGIVTLLAILLIVVLTISEYWAYTTPVMRSQMTVDRYRGDRLDIHLNITFPQLPCSLVTLDIIDSSGEVQQSVDHDMTKVTLDERGNILSSEALTLGENPDSKAVAKRTFLDDPNYCGSCYGAESEPDQCCNTCEQVRAAYATKGWAFTDGSGVEQCEVIGFKEQLKAQYNQGCNIAGKFTVQKVAGNFHFAPGVSSHRDEQHLHDLSHFKDPEAPFTFSHIIHDLSFGEQVDVSGLDWDKGVAMETSPLENTPHHTDNKWFRFNYFTKVVSTRFEFLDGKKIETNQYAATAHERPLQGGRDEDHQNTRHMRGGLPGVFFSYDISPMRIVNKQEYRSHFGAFVMQVVATIGGVLTVAAVLDRGIYEVDQVLKRKKDQ
The following text describes a protein:
Function:
Involved in pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MNFWWLKFDDASTESLRNNIFTNNSITKNMRLNADTILNAQSYINPIGDRELNLRGLQIPVIENLGVTEDHYTSLDLSDNEIRVMGGFPRLETLRTLLLSKNRITQINDVKNIAKLETLVLTQNGIATLGALESLKSLVNLTAITLDGNPVQHVPRYRSYMISILPSLRMLDFQRVTQKERDEAEAMEFDVVPVTETDNLSAVDKAELRERLKNATTIQEIEEIEAMLKV
The following text describes a protein:
Function:
Probable transcription factor involved in plant development.
Subcellular Localization:
Nucleus.
Sequence:
MPLSFERFQGEGVFGLSSSSFYSDSQKIWSNQDKTEAKQEDLGYVVGGFLPEPTSVLDALRSPSPLASYSSTTTTLSSSHGGGGTTVTNTTVTAGDDNNNNKCSQMGLDDLDGVLSASSPGQEQSILRLIMDPGSAFGVFDPGFGFGSGSGPVSAPVSDNSNLLCNFPFQEITNPAEALINPSNHCLFYNPPLSPPAKRFNSGSLHQPVFPLSDPDPGHDPVRRQHQFQFPFYHNNQQQQFPSSSSSTAVAMVPVPSPGMAGDDQSVIIEQLFNAAELIGTTGNNNGDHTVLAQGILARLNHHLNTSSNHKSPFQRAASHIAEALLSLIHNESSPPLITPENLILRIAAYRSFSETSPFLQFVNFTANQSILESCNESGFDRIHIIDFDVGYGGQWSSLMQELASGVGGRRRNRASSLKLTVFAPPPSTVSDEFELRFTEENLKTFAGEVKIPFEIELLSVELLLNPAYWPLSLRSSEKEAIAVNLPVNSVASGYLPLILRFLKQLSPNIVVCSDRGCDRNDAPFPNAVIHSLQYHTSLLESLDANQNQDDSSIERFWVQPSIEKLLMKRHRWIERSPPWRILFTQCGFSPASLSQMAEAQAECLLQRNPVRGFHVEKRQSSLVMCWQRKELVTVSAWKC
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase.
Subcellular Localization:
Endomembrane system. Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Domain:
The RING-type zinc finger domain is responsible for E3 ligase activity.
Sequence:
MAGKEATEGSRRTTLMMPNLTDATLEASRIGKLKESLASEVVGESEKDGSCGCNSSFMCNICLDVAKEPVVTPCGHLFCWPCLYQWLHAHSSYNECPVCKGEVLEGDITPIYGRGSEGESTTNPNFPPRPRANRRDNQRQQLQTEGIARDTSEIESVIVQLIQNQHIVRGLPTPARTTPTTVAEPGSSRQSRPSESPTIRRTRRRPQ
The following text describes a protein:
Function:
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein.
Sequence:
MAKQEYKQLPKRAEVHSATEQFKDTVKTSLGLDLFKGLGLTIKEFFSPSVTIHYPMEQLPLSPRYRAVHNLQRLLDSGSERCIGCGLCEKICTSNCIRIITHKGEDNRKKIDSYTINLGRCIYCGLCAEVCPELAIVMGNRFENASTQRSQYGSKSEFLTSEQDAKNCSHAEFLGFGAVSPNYNERMQATPLDYVQEPSKEESQEETPTNPESNKGDENV
The following text describes a protein:
Function:
Involved in ATP-driven sodium extrusion.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MMDYLITQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAALTTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGSDMSVVQGLNFLGASLPIAFTGLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA
The following text describes a protein:
Function:
Required for normal levels of the cell wall 1,6-beta-glucan. Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Sequence:
MAPIVLPTVLIASAYLLSTVSAAPNVDELVGTWSTKSAAVLTGPGFYNPVNDSLLEPTHTGISYSFTADGYYEEAYYRAISNPAKPSCVSSIMQWQHGKFVLNDDGSLSLNPFSVDGRQLESAPCTADTATYTRYNQSETLQKYQVYTDPYTKLTRLDLYQFDGTPVNPMFLAYSPALMLPTETLNPTSSAKSTSSSKMKRWLGGADEPEEPTTSEGYLLPLNKNAKHISRGIEQPSLIHRIDLDLLWWAGVGMTIFGGAAYLL
The following text describes a protein:
Function:
Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. Is necessary for normal early lens development.
Subcellular Localization:
Cytoplasm, myofibril, sarcomere, A band. Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm, perinuclear region.
Sequence:
MAEAEAMQLKEEGNQHFQLQDYKAATKSYSQALKLTKDKALLATLYRNRAACGLKMESYVQAASDASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPQNQSFQETLRRLNTSIQEKLRVQFSTDSRVQTMFEILLDRNSEADKLEKAANNLIVLSREEAGAERIFQNNGVALLMQLLDTKRPELMLAAVRTLSGVCSSHRARATATLHAVRIDRICSLMAVESEEMSLAVCNLLQGIIDALSGEDKQEHRGKEEALVLDSKKDLKQITNHLLDMLVSKKVSGQGRDQALNLLNKNVPRKDLAIHDNSRTIYVVDNGLRKILKVVGQVPDLPSCLPLTDNTRMLASILINKLYDDLRCDPERDHFRKICEEHITGTFDPQDMDKNVIAIQTVSGILQGPFDLGNQLLGLKGVMEMMVALCGSERETDQLVAVEALIHASTKLSRATFIITNGVSLLKEIYKTTKNEKIKIRALVGLCKLGSAGGTDYALRQFAEGSTEKLAKQCRKWLCNASIDTRTRKWAVEGLAYLTLDADVKDDFVQDIPALQAMFELAKASTPDKTILYSVATTLVNCTNSYDVKEVIPELVQLAKFSKQHVPEEHPKDKKDFVDMRVKRLLKAGVTSALVCMVKADNAILTDQTKELLARVFLALCDNPKDRGTIVAQGGGKALIPLALEGTDVGKVKAAHALAKIAAVSNPDIAFPGERVYEVVRPLVSLLNTQRDGLQNYEALLGLTNLSGRSDKLRKKIFKEKALPDIENYMFENHDQLRQAATECMCNMVVNKEVQERFLADGNDRLKLVVLLCGEDDDKLQNAAAGALAMLTAAHKKLCFKMTEVTTQWLEILQRLCLHDRLSVQHRGLVIAYNLLAADAELAKKLVESELLEILTVVGKQEPDEKRAAVVQTARECLIKCMDYGFIKPVA
The following text describes a protein:
Function:
May act as an adapter that regulates LRP2 function.
Subcellular Localization:
Cytoplasm. Note=Detected in a vesicular staining pattern close to the plasma membrane and throughout the cytoplasm.
Sequence:
MKLSSEKLPKNPFSLSQYAAKQQKFFQWKKEKPDYYLHANLVDTALQFLKERIRRGDAMAYFLRGQLYFEEGWYEEALAQFEEIQEKDHQAIYQLGVMYYDGLGTIANAEKGVNYMRKILDSSCPQTMHLKFAAAYNLGRAYFEGKGVKRSDEEAERLWLLAADNGNPKASVKAQSILGLFYSMKEPKELEKAFFWHSEACGNGSLESQGALGLMYFYGQGIRQDTDAALHCLREAAERGNVYAQGTLVEYYYKMKFFTKCVSFSKRIADYDEVHDIPMIAHVTDCLPEFIIKGMAMAAFYHGRCLQLGLGIMKDEESAKHYYSKACRLNPTLADELHSLLIHQRI
The following text describes a protein:
Function:
Ribosome-binding protein that acts as a regulator of mRNA translation by promoting ribosome inactivation.
Sequence:
MDKSKNLFDLLQDDEEVEKKPTTKSTQAAAAPVAAKKPVAPKTENKVENRSPKLGGQSKPKRVNNGEQQVATSEERQNTKRDSKSYPKHQPRTDATGNIRNRQFDRKSGTGRPHNENKKGGAGQGNWGKEGSVDAETNVATVTPTEGEKESTEPVVAAPVEDKTLTLGEYLKQQGSVTLEAPKLRVAGEGETKNAQWDEFEPIQREVVKQRDTKSVKEEKKTKKNVIQVELKSAPSTQRPKGNTKKVVKGVDVTDVNIFPSLSKA
The following text describes a protein:
Function:
Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
Sequence:
MARGVNKVILIGNLGQDPEVRYTPNGNAVANVTLATSTTWRDKQTGELQERTEWHRIAFFNRLAEIVGEYLRKGSKIYIEGSLRTRKWQDKNGVDRYTTEIIANEMHMLDNRGGGNSGNYGNHSEGGASNKQSAPTSSQTPTAGDDSSVADFDDDIPF
The following text describes a protein:
Function:
RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. Involved in maintenance of genome integrity, DNA damage response and DNA repair.
Subcellular Localization:
Chromosome, telomere. Nucleus.
Sequence:
MQGSTRRAGVMTDVHRRFLQLLMTHGVLEECDIKRLQRHCYKVHDRNAPVEKLEDFINNINSVLESLYIEIKKGVTEDDGRPIYALVNLATTSVSKMASDFAENELDLFRKALELIIDSESGFASSTNILNLVDQLKGKKMRKKEAEQVLQKFVQNKWLIEKEGEFTLHGRAILEMEQYIREVYPDAVKVCNICHGLLIQGQSCETCGIRMHLPCVAKYFQSNAEPRCPHCNDYWPHEIPEVFDPEKEREAGVSKSNRRSSRSRQH
The following text describes a protein:
Function:
Catalyzes the reduction of sulfite to sulfide using reduced F420 as the electron source. Involved in sulfite detoxification and assimilation. Cannot use NADH or NADPH.
Miscellaneous:
MISCELLANEOUS: Expression in Methanococcus maripaludis, a sulfite-sensitive methanogen, leads to sulfite detoxification and use of sulfite as a sole sulfur source by M.maripaludis.
Domain:
Contains an N-terminal H(2)F420 dehydrogenase domain and a C-terminal dissimilatory-type siroheme sulfite reductase domain.
Sequence:
MYEWKLNEIVDSGVCARCGTCTIVCPNGILTFDERPKLIDECLRKGHGMCFEVCPRVSSAKYQIKIREKFYEKYYYAKSDIEGQDGGVVTAFLKYLLENGKIDGAIVVGDECWKPVSLVVQNAEDLLKTAKSKYAISTLDALRKAGEMGLEKVAVVGLPCQINGLRKLQYFPYHAKHDLELGRNGKPVKLPKIEYLIGLFCTEKFRYDNMKEVLSKHGIDIEKVEKFDIKKGKLLVYVNGEKKEFDLKEFEICSGCKMCRDFDAEMADVSVGCVGSPDGYSTIIIRTEKGEEIKNAVELKEGVNLEEIEKLRQLKLKRFKKEVERRRENNEYVSFYWTADYGGIGKRADGTYFIRVRAKPGGWYKPEEIKEILDIAEEYNAKIKVTDRAGYELHGISGFDVEDIVLRLREKGLLTGSEGPLVRATLACPGGGNCSSGLVDTTELARIIEDNFKERPAPYKFKIAISGCPNGCVRPQVHDIGIAGVKYPKVNEEKCNGCGRCAEVCKVEAIDIRGETSYTNYNVCVGCGKCIKNCPNEAREVKEEGYLVYVGGKTGREVVEGVKMKLMSVDEIINFIDKVLVVYGKYAEKPQRERLAAVMKRVGYGKFLEEVKELMKKEIC
The following text describes a protein:
Function:
Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines.
Subcellular Localization:
Lysosome.
Sequence:
MKLKFIFLILFFIIGNSIGIKISKEINKIKLNDISIDGEILLNKSSDSSSSQSSKIINIWPMPKKVLNGDITVYISPHFQFTTNLTKSTTLKKAMDRYYKLIFTEDSKSHSGISILNEIKILVKSEDETLQIGFDESYEIYIDDSGDDGGKIIAETVYGAIRGLETLYQMIGFDYQREYYQIKHCPWIIQDSPRYPHRGVMLDTSRHFYSVDVLKEFIEALAYNKFNVFHWHAVDSQSFPLTSTTFPKITKGSWSSQEIYSTRDIKEIIQHAKEYGIRVELEIDMPGHAYSWGIGYPSVLPANFSHSIQCQQPCPTECNIPLDVSSKESYVIAMGLLEEFNGASMFNESFFHIGGDEVAYSCWNNSLRIVDWMKRENISSFQDAAIFFEIKAIEQLIQLGKTPVMWEDAYLLFGSSGITEKLPEEVVVQIYHDPLLALNTTRDGYKTLQSPYWPYYLDNPSVDWEKVYEFEPSNGIHEKRLRLLLGGETCMWSELVDASNLFAKVFPRAFATAERLWFSIENSNSTTFAKPRLERFRCFLLERGIGAAPLNSTSPDDPNSCYSS
The following text describes a protein:
Function:
Binds directly to 16S ribosomal RNA.
Miscellaneous:
MISCELLANEOUS: Was identified as a high-confidence drug target.
Sequence:
MANIKSQQKRNRTNERARLRNKAVKSSLRTAVRAFREAAHAGDKAKAAELLASTNRKLDKAASKGVIHKNQAANKKSALAQALNKL
The following text describes a protein:
Function:
Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex. The SEC61 channel cooperates with the translocating protein TRAM1 to import nascent proteins into the ER.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MDQVIQFVERSRQFVKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNIIVGG
The following text describes a protein:
Function:
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability (By similarity).
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus.
Sequence:
MPEQLQKLVIDNGSYTIKAGFNTGDDDGNDTSTPIKVTNAISKTKDGIIHVGNQYLSHTNNFSGIQFRRPFEQNNLTSWETEKPIWDYTLDNLLLQTNDQSQSTSSSSSSSLQKHKRGKVIDPDDIHLILTEQPYQLPQLSTNTDQIIFEEYGFNKYYRCIAPSLVPFSVDTNQINDDFVLVIDSGFNSTWIVPMIYQQIHWPAVKKLPIGGNLLNGLLREMISFRHYDISEDPILINTIKESTCFISSSNYQQDLQHKHDLMCEFVLPDFKLTITGFVKNENSMSSQKLPNDTQVLKLYDERFTVPETYFHPEIIFDNNRTTASSSLLNNAPFKNLTDLIVESIMACPSITQPLLSANICLSGGSTNIPNFKTRLIGELRKELPSNWKVNIFDKQYDINRDELSWYGGINLSNESELLQEISISKKDYFEHGANWCQQQFGFKNV
The following text describes a protein:
Function:
Golgi membrane protein involved in vesicular trafficking.
Miscellaneous:
MISCELLANEOUS: Present with 1040 molecules/cell in log phase SD medium.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MDQARNFYNTILKSSHPLLLSFHLAGKAVPIVFYIIGSMFLNFTPQFITVVLLLSFDFYLTKNITGRKLVQLRWWYDSTDVNKDSNFTFESYKQYAPGPPINAIDSKLFWWSMYVTPVIWGVFAVLCLLRLKIFYLILVIVAMCLTAWNTYGFRCCDRWEPNSGQSDGQDTNNWFALPSVPGFENLSRLANIQSFFQRQ
The following text describes a protein:
Function:
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MRAVVSLAVVFVLSYLLGSLVAGVLYSRGRGEDIRGRDLPGGSGTYRQYGKGAAAAVTLADILKGAAAVGLALWLAPQALPLATALATFGVVFGHCYPVWFGFRGGGGIAPFLGAMLVVAPWTLLATVTFALALIPLYRATLQPRLRLNAIPFATVVAVPVGLLIASRLGGGAEFLAGSAAMGIRAVHLLAEQRA
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MDFPGHFEQIFQQLNYQRLHGQLCDCIIVVGSRHFKAHRSVLAACSTHFRALFTVAEGDASMNMIQLDSEVVTAEAFAALVDMMYTSTLMLGESNVMDILLAASHLHLNNVVKACKHYLTTRTLPVSPSSERPAHHHSQQEQQRHRQQQADLGGNPASAGNTSLTGNAATSKVQRSFLLQQLGLSLVSSALGGMEEGGVSNRAVDQRASFPVRRFHKRKPSLALTISEERPRQRQRTSGGANLGLLEEDGENADQDEAALHSPDSHKPGDDSKLGAGITGFVAVAQDDPQMPSQSDSGRSEGENSVRIPGGVNKEEDMGDQDQQASRATVKIKSGNEEEQGEDEERKVVVKREVLSSPEPVDENSDVTSQAEGSDPAEPGCQEEEEKVELSPEGSDRSFTSDPQPSSESLLHSSSQLLLKGSMGGGMGVTGGFGSNNGLSSSSNFNISNFLSSKDFGRGGSGLVSGEDDLPNTTTGEAVAHRFLMRHDAAGPSSSASSSLIQSGTLSGESRNGFGDNLQPDSLFLQPPYENLGGLRGSSGSAGRGGVDPFALDFQRSSLGLHSLGRPSRGMGSASASTLSYPSYRRIAPKMNSGIGGEGRVQDPASPSSNLTSPLLLNESGGYEMNGGRPTSLPPQLTRASADVLSKCKKALSEHNVLVVEGARKYACKICCKTFLTLTDCKKHIRVHTGEKPYACLKCGKRFSQSSHLYKHSKTTCLRWQNMNMSNSLL
The following text describes a protein:
Function:
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
Sequence:
MPTLIVLIGPTGVGKTELSLRLAENFHTSIVSADSRQLYAELKIGTAAPTPDQLKRVPHYLVGTLHLTDYYSAAQYEQEAMEILHQLFTEHEVVVLTGGSMMYVDAICKGIDDIPTVDAETRQVMLQKYEEEGLEQLCAELRLLDPDYYRIVDLKNPKRVIHALEICYMTGKTYTSFRTQQKKERPFRILKIGLTRDREELYDRINRRVDQMMEEGLLDEVRSVLSYRHLNSLNTVGYKELFKYLDGEWELPFAIEKIKQNSRIYSRKQMTWFKRDEEIRWFHPEQETEILEYLRLQNLTHLPSLDTF
The following text describes a protein:
Function:
Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
Subcellular Localization:
Nucleus.
Domain:
The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors.
Sequence:
MYSMMMETDLHSPGGAQAPTNLSGPAGAGGGGGGGGGGGGGGGTKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLKKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVGAAAVGQRLESPGGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGAHPHAHPAHPHPHHPHAHPHNPQPMHRYDMGALQYSPISNSQGYMSASPSGYGGIPYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGSPPAPAHSRAPCPGDLREMISMYLPAGEGGDPAAAAAAAAQSRLHSLPQHYQGAGAGVNGTVPLTHI
The following text describes a protein:
Function:
Transcription factor. Interacts, when in complex with WRKY71, specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Represses specifically gibberellic acid (GA)-induced promoters in aleurone cells, probably by interfering with GAM1.
Subcellular Localization:
Nucleus.
Sequence:
MSGEDGYCSTGTESPRADSVDEQAAADAESPTGGGGPNKRDHPSPSSPLPPPKRSRRSVEKRVVSVPIAECGDRARANGEGPPPPDSWAWRKYGQKPIKGSPYPRGYYRCSSSKGCPARKQVERSRTDPTVLLVTYSFDHNHPWPVPKSSCQPGKSSPRGLTAPKAEPDTPPVDCQPEPLAEPETEPAEATLEQEQDQEQEQEQKPVVGLADPAAITAAAAAEEEESIDYGWFDQYPTWHRTQQYVPAAFDAAPLLPPEEWERELQGEDALFAGLGELPECAIVFGRRRELALAATAPCS
The following text describes a protein:
Function:
Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids. Metabolizes sarcosine, L-pipecolic acid and L-proline (By similarity).
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MREFLKDDYDVIVCGGGPVGLATAYRCAKAGKKVLCLEKSVFFNGGGSSGDVVRMLRTMYTEDYMADLAHETLGLWKELGDDAGEGDLVWMTGLLNFGDPNYGAGGPEGTLLGPIPNLERLGMQYKVLTAQEIMEEYPFRNIPSNHQGVFAPDNGVINLPLVLRSLYKLCLQYGCKMVSHAEVKLIKNLSTTMVEIEVEHTDVDQKNKQSFKVKSKKAAITSNSFCNHIIKPSFGWELDMTIWEMTSSYFVAKPGPNATVFKSMWFNFQNDTDNDPTKSNLYYGFPAVPWMTDNHCRIALDAALRQIKDPNDRHDGVETHDVNRTRDWVREHIPGVDDTPLFNVSALMANVYDNMFVLDFIPETNNNVVMFACGWAMKFIPLLGKILSQLLDEGKTQYPIDHFALNRGNGALIIKEGQTPKSVNSQVRAPRYTSMHCKPLTIAKSTVPTNQSSNPDGASSTAPTQSLRSLFASRLLQRSVGMEAKFHSIIAKNRSKRSTKASQKDLTVGIIGAGMAGLYAAMILQDLGLQYNILEANKERVGGRIYTYRFPQNQDKYQTVELGAMRFPKIEIMDRLLNLDKPWSLFSKLEKAGHKIPTIPYHLTVDNNLVYYNGKRIFANTLLNDDPLYFSDTHNGGPGTAVPDKYTYQPYGDLLDAVYKKFSDDLENDFESGFETLLKSDNYSTRAYLFEKGPYPQSVVNYLETMDTGTGLYDMAFSETIMDYFDFSAGDEWLCIDGGTDIIVNSMVKTLRPGCIEQGKVVTKVSRVVGKSGDVSNLKVDFLDGTEGRLFKHVISTGTLASLRRVDLSDLKLSHNKRTAIRSLHYDHSVKIALSFKSRWWEDSKFMNGKPMLGGKSSTDLPVRTIVYPSYGIGQPGVSGVLIVSYTWSLDASRIGSLVGDRPSEEVLIKLCMANLAEVHNVPVATLQQLFVDYKCWDWYNDDYSSGAFALYSPSQFSQLFPSLTKPSPDGRFHLAGEATSVHHGWVIGSLNSAYRSVDHILQVEGLDELRAKLRLNWGFIDEVEDPQDDQQYVDPHHNLSGPNAKKFRSNVSQVAIQPRFKAPRNFKPRNTAASIGGLK
The following text describes a protein:
Function:
Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MTYSQFQFLPLQVVTSSSFIRSDARTVSAAGDSAETSSQTEDDRYRLLKFTDARDPRHKHLYPISGSMIENYNTQVNPKSRNKSTGKVLEFSDNWCLLPRAGEENEQQQPQRDAPYPHRGHPVLYVPGHWGSFSQARSIGAHGTRWTGHATRSKSDQDVYNSLLTGKGMHDGNSDRALDELLSGLHSSTSSELDFFVMDVFALDFDGGEGAALHSSKLLRQAEFFARAVETIVEGCQNSGQKGITIVAHSIGALVVRIALRMHPHLTSEGWVRNVITLASPLASIPFAVDAGVHDIMKHLNDGDVSDGDVTIISVSGGLRDEMIPPELCEVPSSRSHTTKSKADEGITSSTQVINEAFLSVSAMSTTKQPLAGNAFGMDHRAIVWCYELLKTVREVIFVMVVATDRGIVSSERMEVARKIMKINDNQQTGASSSFRDDVMNQRVALVQEKGYATTVTIQLASPYHLNSLLKICILVALLHSHVTLPLLGLSSRTTALHILLVPLIVTATAWIRRSTASCYMQECQMLLGTTFILAQLAMSAYFLICYGICLILAYLRRKFFHAATTTDVHLQAQSFGHVFLHCFMQQLKAYALVVVLVTAAVYYIHTRLLGGNADFVWNRVAVTSYFFVSTVVLLISSIINVACSSDSSDHHRTIMFVLLLSIIKVTYGKVIYALSLITNWGQIDSQLYDEFLKTMNSSVGSMIGHHKEMILCVATYLVPTFAAVVVIQTHTIMVRNWNLHFSKSLSKAEDGDTDQSLNKASLGHGDRIAILVADVSVVVWYAWNAFVSYGRDDMLVPLYTFATFASFYLRCIPLSSKAMGVYSAVVDNDLSLCSNSPKDHNKKE
The following text describes a protein:
Function:
Plays a critical role in the assembly of axonemal dynein complex (By similarity). Plays a key role in ciliary motility.
Subcellular Localization:
Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasm, cytoskeleton, cilium axoneme. Dynein axonemal particle.
Sequence:
MSNTTVTQKRRTLKVAKSSKTLNVSSGVFRPNQSTTKSINPLFSGKSFGSTGDSKVVDKISAQTPKHTAMVVDENGQDVTPHPLYNPDPGVLQSKQGKVFTALDTSLTTMTEFPSIAFQTTNASLTGPFTRSFFGSASASRISQTAESVTDETKDLLVKQDLSNSISDIQSHREEPKEQLRENILDSTANCYLSETETIWLLDIPAVSVSVESEDAEAVKERNNAYTELCKNRQGNDKYVERSMQTFSDASKTKEVQCDSITMVDKAVMCTVWDMYDSFNNISDVSANTVVSSERHEATIPESSSEGHLVHPKRSNQSLSVVSTVSTVSGSSTHIEKMACVLPLDEEPDLQLILQSDKLKQDLALMERVVLANVFQPKLAAYRQLPIIEDPDCVQMVMEEESWTEQSKNSHCPFLERLWDFSCELTMGRNVSCMVWNKKNPDLLAVGYGQVEFKNPNSGLVCCWSLKNPTWPDRVFHCESGVTALDFSASNANQLAVGMYDGTIAIYNVQTSEQTPITDSSDCANLHTSPVWQLTWIDHEDGLAADKGEILVSVSSDGRISKWIHYKSMECVDLMKLKIHDLQWKRHISSLTPGMCFDFHPNDSKIYLVGTEEGHIHKCSSSYNEQYLESYKAHKRPVYKVTWSPFCSDVFLSCSSDWTIQLWRQDLQIPVMGFTSGQRVVFDIMWSPHCATVFGAVSEGKVEIWDLRVSSLDPTLVNWTSPGVNPTALLFSPETDCVLVGDSEGQVTVYKLKNITAGGGSQGETLEDVIQSTLSSQH