lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
As part of the central apparatus of the cilium axoneme plays a role in cilium movement.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium axoneme.
Sequence:
MDLVITQELARAESQQDAASLKKAYELIKSANLGKSEFDPSESFSPDLFVLCAEQALKMRQPEVSEDCIQMYFKVKAPITQFLGRAHLCRAQMCAPKSAENLEEFENCVTEYMKAINFAKGEPRYYFLVYNASVLYWQMVRPFLKPGYRHHLIPSLSQIINVLSQTEEEDKEWRAELMLELLECYLQAGRKEEAARFCSTAAPFIKSHVPQKYRQIFSVMVRHELMDELQLKEEKKNSISLSVTFYINMLKAKAEQNDLPGDISVILRKAYRHLGHYNHQRFPSISEEKMLLLFELARFSLTLKCMEISSACLSDLKKMESKDPGKLIEMECLECESEALRLESKMKVYNRAAVEAQLDIIQRLDVALQRAVRLGDPRVIHVVCATQWNTCLPLLQHNLRHHLRKPLAGVADVLEKLDSLMTLLRCQVHMEMAQIEEDEDRLEPATEHLRKAARLDSLGLYRDRIQMASTRLRLCTTLYQAPERAEDKAIMAVEQAKKATPKDSVRKKRALLVNAGLALAPDAFQIVLDSENEAKVSTGKNRGRFTYLCAKAWHHTVSVDKAAGHLRRLGNENDKERIQIWAELAKVARKQGVWDVCRTASRFCLLYDNVKVKKLRLRRGKKKRGRDGSVQDTWSQPEVVLQRQVCPDLLRKFAEVGFIHAEATVHLLRSEGVELNDRAIPPEDLSQHPAGYVPEPPEVNAEWITYRTWIESLSRCAMNNWLRSAEIGQEIQEAWIVQNAVVYVLNHNHHLILAGRQKELVDALYHLLSIVKATGHSGDPVMLVTLCNTLARGLIISWIPVQAAEKSRKFMRPNAFHSPLDAGATSEIKTAVEVCEFALNLTNGSAPEETVPTGTRQQLIATWVKAKQLLQQQIGPRLGTEEQGTNEDVSSVTRVLVALEMYSCNGLGLMDFTVPSLAQLVKMASECNWSDPLVELQTLTRLTHFAHAARDHETTMACAHRALEMGIKYLKKFGPEESRLVAEMLCTATAIQGRSIMENLKGRKQLRLVAAKAFTESARFGGIAGSSALVMLAARHYWNAWLPLLSSAVYRKKAKGALKRLIGIINKTEARKQEKGKTLLLHQWPTADFQGGGTTEGYFLPGAEDDLALRAALYGLLFHSHADQDDWEGGLKVLDEAVQVLPRTAHRLLIFKHMVIVKAKLGQNFSMEIQKFKAESEDYLARMWHRLALNSPSVSGELACYNNAIQALQKPEMEWQKVEYLMEFGQWLHHRHFPLEDVVFHLRWAVEILLAMKPPGDVPEPQPTPDGEYVAVEMPPRSPVSEAEEAVSLEQLRSVRQLEALARVHILLALVLSPGAEGYEDCCLAAYAFFRHIWQVSLMTAGKSVLENRPLAATSSHLLLPKKEKENERSKEKEKERSKEKENERSKEKDKEKGKEEKVKEPKQSQSPAPIKQLEDLPMSIEEWASYSCPEEVLSVLKQDRSDSTVNPSSIQKPTYSLYFLDHLVKALQKMCLHELTVPVLQLGVLISDSVVGSKGLSDLYHLRLAHACSELKLREAAARHEEAVGQVCVSELEQASCRKEIALKKEKNKEPLLEESLPALNEQTLPVQPGEIKPLDAKDKILKMNGETGRDLDGTSFPHLWMLKAEVLLEMNLYQPARLLLSEAYLAFQELDEPCAEAQCLLLLAQLANKEKNYGQAKKMIAQAQHLGGSEEFWYNSTLTLAEALLSMEHSGREATVCHIFQKLINAFKILKKERPNRLPLLEFMITDLEARCLSLRVRVAQHSAVTEPTECSLLLKEMDDGLLEIERKFIDCGCKENCVDVKLERAKIKRLRAQNEKDEEQKTAYYLEAYGLAQGAVAEEEGRLHSIQGLYGLAQGAMAEEEGRLHSVQGLLSLQDLQNVNTPLMRKLARLKLGLVEMALDMLQFIWEEAHGQQSEQGSLEKLLADYLQNTSDYTSVGLQWFTLKRTLAHGALAQLGSLQPLSVGCVEIRARLLGLAGRALHLLAMQADPVHPTCYWEAGPSVGAKLSGLKSLELEVEEEGATKSSRDPPASRAAPEEHCRRGEDLKRRMVLAQQYLAQASEVLLQCLQVALGSGLLDVAAAASLEMVECVGTLDPATTCQFLALSQSCSASETMRDVLLAATANTSSSQLAALLQLQHQLRCQDRTTTSLGARVEQRLAAVSKAWQNLCVTEQHFNLLNEMPPTFWILFLHLSGDRSRLYGAAYEKPKFITAAKGKVQAVGGSCKVMRLAISPTAFSHLLACAQQFRKQTQAQVYSEDMALNIGSEPEGLQVEEKERPVQRLSSVLGPLEELLQPLFPLLSLSKARVQTPAVVADSGKSKGKDKERKTSTGQHSTVQPEVADKIVLVADRHLLELPLEGLSVFDEGTISSVSREFSLQMLWNRLHKEETEGGVKKEGRSRDPKKRSLAKKGRKGSIPRTIPPDCIIVDSDNFKFVVDPYEEAQGPEMLTPVSITQDILERFQDTFTSRWAGHLGSKHFPSQAQWEQALGSCSGFFFYGMESFLSHILVERLVAMNLQECQVAVLLDLARSYQSLKRHMESVEHRRSVGRWEANWRNSASPSEDEWRRGGEPRRGFSDLEGQAAAAPKLRAPSHHAQLGPVWAAAPSHRVVQAWTCLPSAAGAPALASALGSAPLPTHPHLPAPIPSSQLALPFLGLSPALGAASARDPPPATSRKAAAWTSSSACLCAPWGLRRGWSCVSSRGQDKGGLPLAALVLSCLDQKTIQTVSLFLI
The following text describes a protein:
Function:
Probable protein O-fucosyltransferase required for correct pollen tube penetration through the stigma-style interface. May be involved in protein O-glycosylation events during pollen-pistil interactions.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MNSPLSSKNLRIFSKSVACKCLVLVGIALFYRALLLSYSPRNALSNSLLFRDRHMSDSSSTGGIRTDKFLEVPQIVWGLNNQKIAFARACLTARMMNRTLLMPSLSASLFYKEVDKLRPIPFDKVFQFERFNSLCSGFVRLSRFSDVKNRAQVFDLEKGSGRRWTVERDLEHLKQSARNESIDEFEVIRLIGKNPFLWHDHWPVEDYAKVFECMVVVDEISREADKVVMKIREAGEAERAKLASKTEILGPVPFVAVHMRIEIDWMIHCKKLEQRKKISEICSSKREILDRVGNISGLKTPTVLYLAVADTLLEEKEEDSSVLSGWRDGLIPFEKKKLGVKEEIYGKYSYLIQSAIDYEVCLRADVFVGNSFSTFSSLIVLERTQKARRLGFMSSCKDGGNKWRSYAYNLAGESNGVPRRWMTNMTHSSLQAISYGSNSVSCSSG
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTITISKELFHVLSPVLYLSRFFCLQPLKWTKTSAGNYIITKSRFYTIYTLAASCLLVITSITGLSQVYQLDVIYLVRLGDTTRRFVTYSDIVVVLLPCVIGPVFALFKTNQTINYLSHLKQFDSLQNQPTKSTKIFQITALTTFCTAFTLSMDLFLWLKLSHNYIFLLCLPYYISYWSTVVIELLFWHFVHLIQIRISVINKKLAKMVVTGLNSVTTLKKPHAEVEDLVKGYEKLIEATNSINYCYGFPILVIILGCLIHLLVTPYGLYSIIMSTGDSTSILSQTVWMTAHILRLFLIIEPCHECFIKTKETSQLICKLLCLSVNQEVKKSLEFFLTYLGECKIEFSVYGFTKINRELLTTIAGAITTYLVILFQFK
The following text describes a protein:
Function:
Probable chaperone protein involved in dorsoventral axis patterning in early embryos. Probably acts by folding and targeting pipe (pip) into the Golgi.
Miscellaneous:
MISCELLANEOUS: 'Windbeutel' means 'profiteroles' in German.
Subcellular Localization:
Endoplasmic reticulum lumen.
Domain:
The CXXC motif was initially thought to constitute the active site of a potential protein disulfide isomerase activity. However, such motif is not essential, suggesting that it has no disulfide isomerase activity. Its precise role remains unclear.
Sequence:
MMHILVTLLLVAIHSIPTTWAVTCTGCVDLDELSFEKTVERFPYSVVKFDIAYPYGEKHEAFTAFSKSAHKATKDLLIATVGVKDYGELENKALGDRYKVDDKNFPSIFLFKGNADEYVQLPSHVDVTLDNLKAFVSANTPLYIGRDGCIKEFNEVLKNYANIPDAEQLKLIEKLQAKQEQLTDPEQQQNARAYLIYMRKIHEVGYDFLEEETKRLLRLKAGKVTEAKKEELLRKLNILEVFRVHKVTKTAPEKEEL
The following text describes a protein:
Function:
Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
Subcellular Localization:
Virion. Host nucleus.
Sequence:
MDARAVAKRPRDPADEDNELVTALKAKREVNTISVRYLYHADHQALTARFFVPEGLVEFEAQPGALLIRMETGCDSPRHLYISLYLLGIRASNVSASTRCLLESVYTASAARAALQWLDLGPHLLHRRLETLGCVKTVSLGITSLLTCVMRGYLYNTLKTEVFALMIPKDMYLTWEETRGRLQYVYLIIVYDYDGPETRPGIYVLTSSIAHWQTLVDVARGKFARERCSFVNRRITRPRQIPLCTGVIQKLGWCLADDIHTSFLVHKELKLSVVRLDNFSVELGDFREFV
The following text describes a protein:
Function:
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
Subcellular Localization:
Cytoplasm.
Sequence:
MAGNAGPKRQDTRKFVENLSGEGKCIAVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIHEGYQGMVDGGDNIKEATWESVSSMLQVGGTVIGSARCKEFRTHEGRLKAAHNLVQRGITNLCVIGGDGSLTGANLFREEWSGLLNELLEQGLINEEAVSSNSVLHIVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFIPEMPPDDGWEDNMCQKLSESRSRGSRLNIIIVAEGATDRQGQHITSSFVKDNRADKKRLNIIIVAEGAIDSHNKAITPDCIKDLVVRCLGFDTRVTILGHVQRGGTPSAFDRILGSRMGVEAVLALLEASTDTPACVVSLVGNQAVRLPLMECVQMTQEVQKAMDEKKFDEAVRLRGRSFENNLSTYRLLSYRKLDSELPNSSFNVAVLNVGAPAAGMNAAVRSAVRVGITEGHKMFAVNDGFEGFAKGQIKEIKWGDVGGWTGQGGSLLGTKRTLPAKRLAKIAEQMRIHNINALLVIGGFEAYVGLLELSSARDEYPEFCVPMVMVPATVSNNIPGSDLSIGSDTALNAITDAFESLLELYEARAHHEEFCIPMCILPATISNNVPGTDHSLGADTSLNAIVETCDRIKQSASGTKRRVFIIETMGGYCGYLATVGGLAAGADTVYIYEEAFDIRDLQANVEHLTQKMKTTIQRGLVLRNENCNENFTTDFIYQLYSEEGRGVFDCRKNILGHMQQGGAPSPFDRNFGTKVAAKAMQWITRALKESYKGGKVFTNAEDTACLLGMRRRAMVFQPVAQLREETDFEHRIPKDQWWLKLRPLMKILAKYKTSYDVSDAGQLEHVTRVRPKDFQPSV
The following text describes a protein:
Function:
Involved in the pathway of sideretin biosynthesis from feruloyl CoA, a redox-active catecholic metabolite exuded by roots in response to iron deficiency in order to facilitate the uptake of iron; this pathway consists in the successive conversion from feruloyl CoA to scopoletin, from scopoletin to fraxetin and from fraxetin to sideretin. Catalyzes the biosynthesis of fraxetin via scopoletin hydroxylation.
Sequence:
MGINFEDQTTLFNFVVREGNGVKGMIDSGLSSVPRPFVQPLSERIPTQKALTCEATQPIDLSNLDGPQHKEVAKQIVEAAETLGFFQVVNHGVSVELLELLKSSAHEFFAQAPEEKSMYLKEVSPSKLVKYGTSFVPDKEKAIEWKDYVSMLYTNDSEALQHWPQPCREVALEFLNSSMEMVKNVVNILMENVGVTLEEEKMNGLMGTKMVNMNYYPTCPSPELTVGVGRHSDMGMLTVLLQDGIGGLYVKLDNGEWAEIPPVHGALVINIGDTLQILSNGKYKSAEHRVRTTNIGSRVSVPIFTAPNPSQKVGPLPEVVKRDGVARYKEFLFQDYMNNFFGQPHDGKKSLDFARAE
The following text describes a protein:
Function:
Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MEPNVRFWITERQSFIQRFLQWTELLDPTNLVLSIEKIEKSRQLLLTNEDASRGDLEDKRIQEAWKRSLSTVHPDNSRLIPGPFRPAALLPFTAPTLFLSMLPVKSLKSMILPQASFYTYSTAFNIVNGNASYDRRAHESLLLGAGVIVSSTFLGLFPRLLQVRLSMNSVLSRNFIPVIILAQLSGMNVIASRSLEPMRGIEVMDKEGNVIGYSRKAGTKAVKDTATSRVVLFGTSAFIPEVFAYFFKRTQFFLQNPWSLWTLKLSCTVLVMGLMVPVSFSVFPQIGRIQCNELEKEIQSATEETELFYNRGV
The following text describes a protein:
Function:
Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. The AP-1 complex interacts directly with clathrin (By similarity).
Subcellular Localization:
Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Sequence:
MQTTHPKNLHLTCSGVERGFTNSPKTHPKMSSLKSFIKAVRASKTTAEEHTTILKESAQIRKNIRQGSNDMRMRRKNVAKLLYLFLLGEPTHFGQIECLKLLSSSRFMDKRLGYLAAMLLLDENQEVLTLLTNSLQNDLKSRDKFIVGLALSAFGNVAGPELARDLSNDIAELCSNHHNYISKKAVLCALRVIQKEPDLESLYIEKTDELLHSKSHGVLMAALAFAISACKINPSLISRFESQADDLIYRIRQLSTSTYSSEHNIGNISDPFLQVKILQFLSILGQNNPKIYDKMSDLLAQVCTNTDSSRNAGNAILYQAVRTILDLNSDSSLRVLGVNILAKFLGNRDNNTRYVALNMLKLVVNSEENAVQRHRSTILACLNDVDSSIQSRALELSTFLVNEANVRFMVRELLSFLDNVSDELRGSTAQYITEVTNAFAPNKRWHFDTLLRVFKSAGNFVSESTLSTFLRLIASAPELHEYAVVKLYAALKEDVSQEALTLSAFWVIGEYGQMLLSPTMNFDDDQTLPHSVSESDIVDIIEEVFNSVEASRYIIVQYGLFALTKLSARLGSSSTASRIDKIIYSYKRNKNTEVQQRSVEFHLILNDSKLSKTILEPTPAPLPPPRTTPYQNAEQKLKANKHVEKRVQESNELLDLIGLTTPSVAEPLETPVDEMTQSPQSSLSRAPSTSKKSHFEDILGLFASPAPSAQPVDSLASSFASLDFNASASQPSNNLSLLSSIPSTSKSYPPIVVFDKHDVTLTLVPSKEESTKTAVIEAKFKNKNPMTRVEKIHLEVAVPKSQKLKIQPLRTTSMEPGGETSQTLRVHGPSGSQVKLRLRISVVRQGGSNTLDQVDFGKLPSDLLQ
The following text describes a protein:
Function:
Plays a role in autophagy. Functions at the preautophagosomal structure (PAS) in order to form normal autophagosomes under starvation conditions. Also plays a role in mitophagy and regulation of filamentous growth.
Subcellular Localization:
Preautophagosomal structure.
Sequence:
MKPTIYLRFPFNRNGFEDPATPATALSDKQLSDFISKLVSQAPIDWHKTALSYHVSVVHLLQLACHLYDKKGKGLNDETQRRNWVDKLAHASLPETRDVNAVNMASRDHSNSTTSANSHSNSSVPSLIKSREKSLVISPTDDAVFASVDHMSNPHVEISHATSGTATTNTDPHLFSSTDLEGVSASALEEAILSALND
The following text describes a protein:
Function:
Actin nucleation and elongation factor required for the assembly of F-actin structures, such as actin cables and stress fibers. Required for cytokinesis, stress fiber formation and transcriptional activation of the serum response factor. Binds to GTP-bound form of Rho and to profilin: acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics. Also acts as an actin nucleation and elongation factor in the nucleus by promoting nuclear actin polymerization inside the nucleus to drive serum-dependent SRF-MRTFA activity.
Subcellular Localization:
Cytoplasm. Nucleus. Note=During mitosis, co-localizes with the actin-rich cleavage furrow and with the microtubule-rich central spindle during cytokinesis (By similarity). Shuttles between the cytoplasm and the nucleus (By similarity).
Domain:
The DAD domain regulates activation via by an autoinhibitory interaction with the GBD/FH3 domain. This autoinhibition is released upon competitive binding of an activated GTPase. The release of DAD allows the FH2 domain to then nucleate and elongate nonbranched actin filaments.
Sequence:
MEKHRARALGRDSKASRRKGLPSAPPAGPYELGEKRPKLHLNIRTLTDDMLDKFASIRIPKGSKKERPPLPQLKTVSGSSDYSSVSSETMENNPKSLSENEVLKLFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLRSSRQISPQEFIHELKMGYTGERLFTYLESLRVSLTSNPVSWVQNFGHEGLGLLLDILEKLINGQIQEKVVKKTQHKVIQCLRALMNTQYGLERIMSDERSLSLLAKAMDPKQPSMMADVVKLLSAVCIVGEESILEEVLEALTSAGEERKIDRFFSIVEGLRHNSVQLQVACMQLINALVTSPDDLDFRLHLRNEFMRCGLKEILPNLKGIKNDGLDIQLKVFDEHKEEDLSEFSHRFEDIRAEFDEASDVYSVVWDTVKETRAEGHFVSILQHLLLIRNDRFIRQQYFKLIDECVSQIVLHRDGIDPDFTYRKRLDLDLSQFVDVCIDQAKLEEWEEKASEHCKKFEKECTDHQETQAQLQKKEAKINELQAELQAFKSQFGALPPGTKIPLQTSAKGEPGPSAFPPAPPALGAGVPPPPPPPPPPPPPLPGMAMPFGGPVPPPPPLGFLGGQNFIPLNLPFGLKPKKEFKPEISMRRLNWLKIGPNEMSENCFWIKVNENKYENKDLLCKLENTFCCLEKEKRDTNDFDEKKVIKKRMKELKFLDPKIAQNLSIFLSSFRVPYEKIRTMILEVDEAQLSESMIQNLMKHLPDEEQLKSLSQFRSDYNSLCEPEQFAVVMSNVKRLRPRLTAILFKLQFEEQVNNINPDIMAVSTACEEIKKSKSFSKLLELVLLMGNYMNAGSRNAQTFGFDLSSLCKLKDTKSADQKTTLLHFLVDVCEEKHPDILPFVDDLAHLDKASRVSVEMLEKSLKQMGRQLLQLEKNLETFPPPEDLHDKFVIKMSSFIITAKEHYGKLSTLLDNMTQLYQSVMSYYAVDTKKVSVEEFFNDLNNFRTSFMQALKENIRKREAAEKEKRARIAKERAEKERLERQQEKKRLLEMKTEGDETGVMDSLLEALQSGAAFRDRRKRTPKLKDIRQSLSPMSQRPVLKVCNHENQKMQLSEGSRPHHSINCTSTRTPVAKELNCNLDTHTSTGRIKAVEKEACNAESNRKKEMELLGSVSKSESVPEVEALLARLRAL
The following text describes a protein:
Function:
May act as a carbohydrate transporter.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MSSLMICYLFLLLCLLCEGREILVGGKSNTWKVPESTEETLNQWSERTRFKIGDALLWKYNAENDSVMQVSKKDYERCDRSEPIKGYKDGHTKIELKRSGPFYFISGEDGHCQRGEKLLVVVLSPNHNRSYTADAPLTTPVTDKGSDHVLINQAQRSIATACLIFLLPLVLFGLVLLPL
The following text describes a protein:
Function:
Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3' (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MLLDAGPQYPAIGVTTFGSSRHHSAADVTDREVGLGINPFADGMGAFKLNPGGHELASAGQTAFTSQAPGYAAALGHHHHPPHVGSYSSAAFNSTRDFLFRNRGFGEAAAASAQHSLFASAAGGFGGPHGHGDAAGHILFPGLHEQAAGHASPNVVNGQMRLGFSGDMYGRAEQYGQVTSPRSEHYASSQLHGYGHMNMNMAAHHGAGAFFRYMRQPIKQELICKWIEPEQLANPKKSCNKTFSTMHELVTHVTVEHVGGPEQSNHICFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSSQGSQPSPAASSGYESSTPPTIVSPSTENQTASSLSPSSSAGHHTASHSTLTSNFNEWYV
The following text describes a protein:
Function:
AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with broad substrate specificity that uses the proton motive force to export substrates; (Microbial infection) Involved in contact-dependent growth inhibition (CDI), acts downstream of BamA, the receptor for CDI. Its role in CDI is independent of the AcrA-AcrB-TolC efflux pump complex.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKNEDIEHSHTVDHH
The following text describes a protein:
Function:
Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
Sequence:
MRSDIIKEGPERAPNRSLLKATGVTDSEMKKPFIAVVNSWNDIIPGHMHLNKLAEAVKAGIRNAGGVPFEFHTVGVCDGIAMGHEGMKYSLPSREIIEDTIELMVKAHQFDGMVLIPSCDKIVPGHLMAAGRLDIPAIVVTGGPMLPGYVDDNYRDLISVSEGVGAYSAGKISETEFKRLENLSCAGAGSCAGMFTANTMACMTEALGLSLPGCATAHAVDAKKILIAKESGERIVELVKENLTPRKIVTQKSFENAIMVDMAVGGSTNTTLHLPALAHEFGLGLPLEAFDELSRKTPHLISLRPGGPNFILHFDRAGGVEAVMQRLASKLHLDQLTVNGKTIGENLDELEIVNPKLNAEIITTLENPIHAEGGIAVLKGSLAPDGSVVKQAAVDPKMHVYTGPAKVYDCEEDAMKSILAGDVKPGDIVVIRYEGPKGGPGMREMLAATAALGGRGLLESVALVTDGRFSGGTRGPCIGHVSPEASDGGPIALVKDGDLIEINIPERALNLKISEEELKQRKASFVPPKTEITGYLARYQRAVHSANTGGIVD
The following text describes a protein:
Function:
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MPIDRYQIRNVYSLADQELYKAADKDDPEALLEGVAMAGLVGVLRQLGDLAEFAAEIFQELHEEVTATAARGHGLLVRAQQLELEIPSIQRSFMSQTCHSAFFTNSGVDWHPNLKTTPNLITTGDLPRFVMNSYEECRGPPRLFLLDKFDVGGDGVCLKRYTDPSFYKVEVSLNEIENAEIQRDKKIRKNKKKGSQCKVGGTPEISPNSKAKLHQLFMEDRMQNSTTEYTHRVKLKKRPNKSPFDSETYINKLLKSPSSKGKIVHPLPFHPSIIPVPFDSPNQIFKDTIGSPFNLATPSRSSSVSSSAENTGCRIPADNLAGKVIDRKISDLTNSGSPDVNEEIKTDGVQNGYRSDDVASEMDNYVDALGTMESGLQFQFSDSQSTRSTEILFHPRGPLEKTPRTSYDMNEGVVLEEDENLKNEENQTDFHSPAGSLLSFQFFGNFEGEVEHEHEHPNDGSSPMIHPPNILETADKINEDNHNHSTKDDSVVEETLDSCEKFSLPEEKLNEIGDDEPKVSSFIEDEKELKERETGLVNSETTPDDVDRNDDKALSTLEDDTKSEGREEDSVDPKMEKNVVVLLPLDVNTNENNARNDENALPTLEDDTPLEGKGEEDSVDLEEMKNIPPDLDEDDVDRNDDNALSTHSLLEETNENGEKTVVVLNDIGSQPMTVTEKPPMLELPPSEMEDKEDPQLLFASAGSQFSSQSDSPSHDIDQFDQVNHQLPPVKLEDTPPLPPLPPMQWRMRKLESPMLTPTDGGQLKVNEIKNTEIENEKFENEGSLHAQDHDKKSASTEVKFSEILAPKEAVDEIPNNIRPTKIQRPRNPLIDAVATHDKSKLRKVLAMSQITKGQENDKLLEQIRTKSYNLKPPAQTRPNIQGPTTNVRIAAILEKANAIRQAFAGSDDDDDDSDSWSDS
The following text describes a protein:
Function:
Involved in 20S proteasome assembly, facilitating the alpha-ring formation.
Miscellaneous:
MISCELLANEOUS: Present with 1820 molecules/cell in log phase SD medium.
Sequence:
MISYEFQTHLPKGKDSSLNASSENKELYVQATHFNNTILLQIRLNGEMDSTYEVSSKGLNPILDINVPLAGNLGNTGGDYDDEEEEFVRDHLSDYQVVTKLGDSADPKVPVVCVQIAELYRRVILPEVSGTMAQDNMQFSLLISMSSKIWRATKEQSADDNDFGKLVFVLKCIKDMYAK
The following text describes a protein:
Function:
Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex).
Sequence:
MAEFPFEISPMFEGERVRKEGMFVELGGPKSLGLELVRAADMDAIEDDKVTIVGPDLKDMEEGKTYPWAMIFNIGGELVEPDLESVVERRVHDFINYCQGIMHLNQRYDVWMRVSKDTAGKMDSFEPFGKAVMMLFKTELPFIEKMQVTFYTGKEEVEKQMELAKEIFKARDARTKDLHDEDVDVFYGCTLCQSFAPTNVCVVSPDRISLCGAINWFDGRAAAKVDPEGPQFEIAKGDLLDAVTGEYTGVNEIAKKLSSGEFDKIKLHSFFDSPHTSCGCFEVVGFYIPEVDGIGWVDREYQGMAPNGIGFSTMAGQTGGGKQIVGFLGIGVNYFYSPKFIQADGGWNRVVWLPSGLKAKIDEAIPADLKDKIATENDATDIASLKDFLEAKNHPVVATWAAAEEEEEEEEEEEEVAVAAAPMMMPAAGFQMPAMPMMSGGSGGGIKLTFKNAKITIDKLVISEKKEKK
The following text describes a protein:
Function:
Seems to act indirectly to modify IME2 activity, thus permitting IME2 to carry out later meiotic functions.
Miscellaneous:
MISCELLANEOUS: Present with 1850 molecules/cell in log phase SD medium.
Sequence:
MDNQQESISEDITGDLAAAVRKSWSESQDNPLLLNFNNSPIGTPTDRYSPEPATMMEGNAMNLSSLARGSTQQQQRLYGSSQTREKSDQQQQDYQLFKHHYSLGQETRESVSDILNDLTLGSPEPSERASPIRQPSVDVPPLTTRRSSIQDVQWIRHLLNPRSSFSGASSNEPTNSPGDFLNQSRAWITILHDSSAESLQAVIVLAESLKNVNSQYNLWVLHSSEVNAFQLAQVGIKTLIIDEYINLFMNFGTGSGFSASSQSTETKGELNFKWCKLFLFFSLIDRFELICYLSPTCLVLQNIDELLESTEVSDEIDNETCVLLSNKVNYINEDLVSVNQDQSSAENYDDDPQIIILKPNRAVAMCIKEYFTIYGNDFEGESKRSMFHQMNDLQIMKALFGDKWSYIDSVGYCAVPIASVPANRLNYKIIEFKILKPWERQNYIAAGQHRESIMNKWLDLWRDFLNQAN
The following text describes a protein:
Function:
May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function.
Sequence:
MATFRSRMPLFAVSKAFVSTLGRAAKTFRPFSTSRNLSSPESKRVVVTGLGLVTPLGAGTKTTWSRLLNGECGITAVQGPGYEKIPCQVAAHVPRGAEEGQFDADKFVSAADKRAMTDGMIFALAAADEALQDAKWKPETEEDSNMTGVAIGTGMVSLQDIVDTGVTLRERGYNRVSPYFVPRILVNLAAGHVSMRYNLKGPNHAVSTACTTGLHAIGDAYRFIKFGDADVMVAGGTEASINPLAFAGFSRARALTTKFNDDPQTASRPFHPDRDGFVMGEGAGVVVLEEYGHAKRRGATMYAEVVGYGLSGDASHMTAPSETGDGAMRCMKRAMQCAGVTPSEVTYINAHATSTPLGDTVENTAIKTIFNSCTSSLAVSSTKGAVGHLLGAAGAVEAIFTVLACADGMLPPTLNLTRVDKEFDLNYVPCKAQEWKVKDGRKRVALTNSFGFGGTNASLCISSIN
The following text describes a protein:
Function:
May function as activator of the canonical Wnt signaling pathway upstream of ctnnb1/beta-catenin. Might be required for dorsal axis formation.
Sequence:
MGTPGSGRKRTQIKDRFSAEDEALSHIAREAEARLAAKRAARAEARDIRMRELERQQKELTHRYHDKKWGQIQKWMEDSDHARHLQRSSHRHSMASSRVTPNHRSSSVDVSGSHRGRESISRRRDSVYNTLKDSSRRTSNSYSNSYDVKNTTSSSHRDLLSGLYHDQRKYSSLKYNKPISTHHIRSSSLYSEPLATKRTYGTSLYKDGLYNASSSRAPSEYSCYSSRASSARSSPVCSDDEGSVSYSSCRGRRDSVSSDFSDQSESAADYFSRSNRRGSIVSDVDDVSIPDLNSLDEKTDKQFTTENYSRPSSRNATSGIPGTFTPLSGSSSRRGSGDASCSLDPDASLSELRDIYDLKDQIQDVEGRYMQGLKELRESLAEVEEKYKKAMVSNAQLDNEKSNLVYHVDTLKDVIEEMEEQMAEYHRENEEKSKELERQKHNCSILQHKLDEHKEGIRQRDEFIEENQRMQQRVDSLVREVYDLQETINWKDKKIGALERQKEYFDCIKNERDELRDELTAVKEKVKIGEKHGLVIIPDGTPNGDINHEPMVGAITVVSQEAAHVLESAGEGPLDVRLRKLAEEKEELVAQIRKLKLQKDDERQKSAKNNSTTTDPTGLENGSDLQLIEMQRDANRQISEYKFRLSKSEQDITTLEQNVMRLEGQVVRYKSAAENAEKVEDELKAEKRRLQRELRTALDKMEEMEMTNNHLVKRLEKMKANRTALLSQQ
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Sequence:
MPPPAAVASLTLQVPGGAHDVTSLATSPRTMAVPGTTEQLTIFYSGSMVKFDNVPREKIRYACRLRRLYSSLQRSLQTQDTSMFPSSSSLHIQTKRRGYSVIRLLREMLMVCSSTRTKPMLVHSDSIGAQRTGTPPSRRRIHARGKSRSCQEMSHCW
The following text describes a protein:
Function:
Not known. Could be involved in the processing of hydrogenase.
Sequence:
MPTSSQDNRILVLGIGNILWADEGFGVRAVEEFHRRYAVPDNVTILDGGTQGLYLVNYLEEADRLIVFDAIDYGLEPGRLKLVRDDEVPRFTGAKKMSLHQTGFQEVISAADLLGRCPKHLVLIGCQPLDLEDWGGPLTPPVRDQIAPSIDLACQVLAEWGVTVSRRSAPLAESERLLANDIDHANYEMRPA
The following text describes a protein:
Function:
Mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. May play a novel role in the organization of septin structures.
Miscellaneous:
MISCELLANEOUS: [Isoform 3]: Incomplete sequence.
Sequence:
MFSRNHRSRVTVARGSALEMEFKRGRFRLSLFSDLPEDTELQRKLDHEIRMREGACKLLAACSQREQALEATKSLLVCNSRILSYMGELQRRKEAQVLGKTSRRPSDSGPPAERSPCRGRVCISDLRIPLMWKDTEYFKNKGDLHRWAVFLLLQLGEHIQDTEMILVDRTLTDISFQSNVLFAEAGPDFELRLELYGACVEEEGALTGGPKRLATKLSSSLGRSSGRRVRASLDSAGGSGSSPILLPTPVVGGPRYHLLAHTTLTLAAVQDGFRTHDLTLASHEENPAWLPLYGSVCCRLAAQPLCMTQPTASGTLRVQQAGEMQNWAQVHGVLKGTNLFCYRQPEDADTGEEPLLTIAVNKETRVRAGELDQALGRPFTLSISNQYGDDEVTHTLQTESREALQSWMEALWQLFFDMSQWKQCCDEIMKIETPAPRKPPQALAKQGSLYHEMAIEPLDDIAAVTDILTQREGARLETPPPWLAMFTDQPALPNPCSPASVAPAPDWTHPLPWGRPRTFSLDAVPPDHSPRARSVAPLPPQRSPRTRGLCSKGQPRTWLQSPV
The following text describes a protein:
Function:
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
Sequence:
MERQGGEEVGLQYQWFNTTAASNNSNPIVPSSYTLPENHLRRESASENHHIYWDPTSGNPIVFQNAMLPNNPYQNLTPSQNTNPNDHLFFPANSLPNLSCTNNLNINGTDFADQAQHHQLTAALNRLSISNHHQSGGATLNPRVNSSSGGNGFTAQYQSSHYIREEEEYLERLKNQYILLMAEMDQYMRLHGSPVANHVTTSNHALPHRANFPLTDVGSTYTGASRVGSITSDQFGYGYNPMRPNNPVRNGVISSRGSRYANGSGRQRLSPSYSSSSLEQRGQVMTSNSVAKDGSRFSNGSLRQQHPTAFNLSLEELRGKIALVAKDHVGCRFLQKKVEEGKPEEVEMIFKEVMDADLRDLMVDQFGNEFIQKLVEATNKEGQSKMLDCVMSDEKKLKDICADQHGSRAMQKLLERVETREQQSSFMRLLKRITIPLSKTQPGYYVIQVCLKHFSPESTKGILELVLENCLALAKDKFGCCLVQSSVHYAYTEAKERLVADITEHARVLSEDPYGNYVVQYIIGLKIPRVTADILAQLRGSFVNLSMNKYGSNVIEKSLKEAGEEHVNRIINEMINSPNLLTLLQDPYGNYVAQSALGVSKGAAHNALVQLVRSHYPYLHSHLYGKRVLDKTRGHRNRC