lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDFTSDYAHRRMVKFLTIILIGFMTVFGLLANRYRAGRRERFRFSKANLAFASLWAIAFSLVYGRQIYKEYQEGQINLKDATTLYSYMNITVAVINYVSQMIISDHVAKVLSKVPFFDTLKEFRLDSRSLYISIVLALVKTVAFPLTIEVAFILQQRRQHPEMSLIWTLYRLFPLIISNFLNNCYFGAMVVVKEILYALNRRLEAQLQEVNLLQRKDQLKLYTKYYRMQRFCALADELDQLAYRYRLIYVHSGKYLTPMSLSMILSLICHLLGITVGFYSLYYAIADTLIMGKPYDGLGSLINLVFLSISLAEITLLTHLCNHLLVATRRSAVILQEMNLQHADSRYRQAVHGFTLLVTVTKYQIKPLGLYELDMRLISNVFSAVASFLLILVQADLSQRFKMQ
The following text describes a protein:
Function:
Involved in the placement and assembly of flagella (By similarity). Activates the SRP-GTPase activity of FlhF.
Sequence:
MQMNRYDQAATLRAKMEKRERVLPMVYSQKAKTLAVISGKGGVGKSNITLNMALALQDKGKKVLLIDLDIGMGNIDILIGNSSSATIIDVLTDRKPLLQSLSVGPKGLRYISGGTGLDVMFQLDQRKWTFFANELSHALSQFDYVLFDMGAGLSKDQLPFILSAEDILIITTPEPTAIMDAYSAVKHLVLTENKLSMKVAVNRCRDQKEGLDAFARLSRTIHMFLDVQVQFAGSVSDDVIVSKAVVEQVPFFIKSPQAKASRSVRILADALFEREETRHKEDKQTFIEKLSSFLMRRA
The following text describes a protein:
Function:
Putative cation exchanger.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSKTSCFLKKYRLILLWCILGIAYILFWTHRISKAFASVSSTSDSTVHLFERGNTLNDSNDQILLTCNDIKNITPANQCRFAKAYCKGEASGFFDYVEFYFCTINSLRFPVLSIIVGWLIFLFITIGISASDFFSTNLVTISWLLQLPDSVVGVTFLALGNGSPDILSTFAAVRVNSGGMAIGELLGSAFFIVAIVAGSVCLIKPFKIPRRHFLRDVAFLTGTILLVIMFVLHDGSLSIWQSLVMILYYLLYVLFVFFSGSSGVSVVITDENYLPVSLPVYSPVLNSFDDSDSYSSTDSELSEEAFLLPAQASRKTQKIHYINDNDPSNSYSSYQHSHVHDFIHKNNTHSNRVLSQSSGPIVRPSLLAALDFRSSNEEQHPGLRSLDPLNIQDGDLTMHPMHIRHSQSDFYPSGINTPVSGINYPNLGFSANNSVQSLVSEIFRHPTHTDEDFPLPSPSLSSLLFPTLRNFAKKSWYEKLMDVLAVPSVLIFTLALPVYQCPRLAVDPIYHMDVSNCNPSKPTWSRKLRLLQCVFVPFAFVTFSITGGNRLYIYAASSVFSILCITALYYYTDEEKPPKFLPWVSFIGFVLGIIWISTIANEVVGILRALGVIFNLNESILGLTVFAAGNSLSDLIADIMIARSGFPEMAMGGVFGGPTLNILIGIGISSFYSSISNHGNDSVIEIPHSLSITAYFLLACLLLLLIYVPLNRFRVNRVLGLLLFILYIVGTSTNIVVELLKDK
The following text describes a protein:
Function:
Involved in the hydrolysis of the beta-gamma-phosphoanhydride linkage of triphosphate-containing substrates (inorganic or nucleoside-linked). Catalyzes the hydrolysis of inorganic triphosphate (PPPi). The enzyme has a strong preference for linear PPPi compared with cyclic PPPi (cyclic trimetaphosphate) and to the linear P4. The longer chains polyphosphate are not hydrolyzed. It has only a slight thiamine triphosphatase (ThTPase) activity. Nucleoside triphosphatase activity is negligible in the presence of magnesium, but a small activity is observed in the presence of manganese, in particular with GTP.
Sequence:
MTEIERKFLVATFPDGELHAVPLRQGYLTTPTDSIELRLRQQGTEYFMTLKSEGGLSRQEYEIQIDVTQFEMLWPATEGRRVEKTRYSGKLPDGQLFELDVFAGHLSPLMLVEVEFLSEDAAQAFIPPPWFGEEVTEDKRYKNKALALSIP
The following text describes a protein:
Function:
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSLLFDFFSLDFIYYPVSWIMWVWYRLFAFVLGPSNFFAWALSVMFLVFTLRALLYKPFVRQIRTTRQMQELQPQIKALQKKYGKDRQRMALEMQKLQREHGFNPILGCLPMLAQIPVFLGLYHVLRSFNRTTGGFGQPHLSVIENRLTGNYVFSPVDVGHFLDANLFGAPIGAYMTQRSGLDAFVDFSRPALIAVGVPVMILAGIATYFNSRASIARQSAEAAANPQTAMMNKLALYVFPLGVVVGGPFLPLAIILYWFSNNIWTFGQQHYVFGMIEKEEEAKKQEAVRRRAANAPAPGAKPKRSPKTAPATNAAAPTEAGDTDDGAESDASTERPADTSNPARRNSGPSARTPRPGVRPKKRKR
The following text describes a protein:
Function:
Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm, sarcoplasm.
Domain:
The beta domain is required for enhancement of transcriptional activity.
Sequence:
MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEALNKKENKGCESPDPDSSYALTPRTEEKYKKINEEFDNMIKSHKIPAVPPPNFEMPVSIPVSSHNSLVYSNPVSSLGNPNFLPLAHPSLQRNSMSPGVTHRPPSAGNTGGLMGGDLTSGAGTSAGNGYGNPRNSPGLLVSPGNLNKNMQAKSPPPMNLGMNNRKPDLRVLIPPGSKNTMPSVSQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTEYSLSSADLSSLSGFNTASALHLGSVTGWQQQHLHNMPPSALSQLGACTSTHLSQSSNLSLPSTQSLNIKSEPVSPPRDRTTTPSRYPQHTRHEAGRSPVDSLSSCSSSYDGSDREDHRNEFHSPIGLTRPSPDERESPSVKRMRLSEGWAT
The following text describes a protein:
Function:
The Set1 complex specifically methylates 'Lys-4' of histone H3.
Subcellular Localization:
Nucleus.
Sequence:
MNLELLDPFSIPDYPEALTTTLKHGHATSIRFSTNGYHLASGLVNGSVVIWDLSTFSVSRVLTGHTRAIQSVCWSSCDRFLLTASRDWKCILWDLRDGSIVYQVVLSAPVWSASLHPHKINTFVASLLDESPQLIIVDDGIPKHKYLPTNPDIDENYSDRRNRSKHVTLVSFFHPSGEYILSGTSKGWFHVIDASTTKIRSSHRITSQSIKQIRLSFCKRFLIFNSTDRVIRTVSIQDLDNPEVEHKFQDVVNRLQWNSCGFSQTGEFVFATTYQMAHAIYVWERGMGSLVKILEGPKEELVDVDWHPVFPCVASVGLDSGSIYIWAVEQKESWSAFAPDFQELEENIEYEEPEDEFDIHDETGKSEEEEYFTSVVKILPHDSSAEQPFVMPPTLSSS
The following text describes a protein:
Function:
DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
Subcellular Localization:
Nucleus, nucleoplasm.
Sequence:
MPVCSAYKCKKRSDREYKEAYKRGEFSFHKFPLEDGLRVREWLRRMRWQNWWPTGNSVLCSDHFEKDCFEQVGSHKRLRKSAVPTIFNFPKHLQWKVPAVKRRSLNRTPVAVPIKPKPTLVSAPVTPRLEGTFVRVNVDSNGSSRGLFHAGSFHDDYCKPQSFHWMKLSEGDGESDDDSSDPESDVTSDDAPLETPQNPNSKFIKVTERWQWLSIDVTGPFQESKGPYSHIVVICDYYTKWIEIFPTEKPNSDSVALLMCDAISRYGFPLGFLTPWGARGIQVRTVNRALNNILMIKDISLVSRHHQASQLEPHTQYHIINMVENLVKKHPDSWHVHLPVSVLRFNCSVHPETKHRPLVLHRCEGKKPYTSPRDQPLSEDDLAKYSFKIQKPNPLKEIEALKRIFREYNPMLSEALSVSAFPLHLWSLTFQI
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Sequence:
MKAPKAPLEVPESLCFQILGPEEIEKHSVARFDAKSELEPTKKARCKAKYAKLGVPYNAIGKCPTCGAYGRKCPGHFGHTDLAGPLFRGEEENKIIADVMRHLCFACGRPSRMKTRLAKIQDLQENKCLNPMDRRSMTEIAGNIRGPSVSATHPVLAQAGGLVLKGATRGILLRNWSQILCESCGASFKKLATTHPEMAIPRGFSALAILDALKRISDDDWARCPLRNSGRISVARPEWLLLTKLPIPPPHLCLTIAPLKKLVAKNRCLKREHAAAMRRDPDRALKLLAHRLPSELQPLANEHFGTKGTVSADVMEQVNALVGRSDGTGEERTPERKADAERNEGSGWVPRPDGEEGPGWGSGSNWDENKEQETEPEPERKPEHERKEKSAERKPAIKRRFFRKGKPLMLVPGATLKVGDTLERSLRNGDRVVINRYPSLHKGSGFSVTVRVSETKTFALHPAMCRGMGADFDGDTIVIHVPQAPEPSADVQSLLPIEENLVSPSGGEAMVTFLQDSLLALSEMVSTLTTFFTQEEAQNHFANVLLASGSEDGLTLNHFPEPAIWKHPGSEVLAGGKRVKNPVWTGPQLVAALLPDGFEYESPGDGLALIGGEFVEIDREGQLMVSVGRPVRGSAWLQPGPRGLVAALDQMSKENAFTPTTGPVCGPRGAAAALDALLALAHSVMDERGFSVGLADVTFADALKADVRWELFEAFQRETRGAAARAMAVRPKQVLGAFGKGRSREDENCAPGLMLASQSSAKAVQTIFKDYSSRLARLLLPVLPPTNAFKRMLDAGSKGSPSDLVQLCLAVGLQGHLGSGAFPLAVRQELYGAHFFSEDEFGSRLSADDAAARDAKARNCSLDQYREAAEPRARLQLLYAQANLGLVPVGFGGAVLARAREQEPMSDALRACGFWCTAQAGRDRNIAHHLLTALPHGIGSGLRAQMADVKLAYDGTCRDLSGTILYFNKEAEGPNDVDATRGALQLDPEESAGSLASYALSEPMSQQALKSKHPGQYAGETLDALELALQLKTPGSKFCHVILPFVPEVKTGEEGAATPEITSAREITSRDPATRKCHALMDKIRHVTLKDIAAAWEIRYDPKTAQRAYDQRSNFILSIELTKQAIFDHHLFDAVRTLDLPRVLGDAQPGFRARVWTEVTCHKPEGGAECPACAQMAADLAAEARLAARAENSSVDGSGYEEDPPSVFDSTARKLRGMSRQALREYAAVRGTPEVISGSCSSASLITRIIDCCKIHSEAFFIENHQVHLLAVLADHEIDLRAPKKFPGIAAGDEAGVLMGAQNARIREAEDFLRTTLKGDPMVTDLKPTFTEYNLLFPRPTPVEPSPVTASSAEPPLSTPGRLIGEVTLEVTLRRPTGKALKRWKPVAHAAAAAGGLVDAVDWNRAVLKHPGDVEKVYGLGTAEAMVKKTVTSLYAEAKAPVYEQHINLVAACMAKSGKLRPFTSAALNQSLGAARRRTEKHRAETAPMRRAHYGGAFSTFQQAALRGGTETLASAVSLSAFGRNVPLGTGGKFDLLLDLTRFPPATVIPERTWLCVEMPDAFRETEAARASGEEKRLAGSGNRKNASGTEKALHAVTAVHVSVVHHSVAGRASPAAFFTAVCVCGKELPEWIGAEHTLFPRWKARTLTHDGIRDARYFILRLGDSGVQHPPEGEGHLSAERLRDGGESDGC
The following text describes a protein:
Function:
Sorting nexin, involved in the separation or division of vacuoles throughout the entire life cycle of the cells. Involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network, for cytoplasm to vacuole transport (Cvt), and autophagy of large cargos including mitophagy, pexophagy and glycophagy. Involved in proper sorting of the v-SNARE protein SNC1.
Miscellaneous:
MISCELLANEOUS: Present with 358 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm, cytosol. Preautophagosomal structure membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Note=Endosome and other perivacuolar punctate structures. Associates to phosphatidylinositol 3-phosphate, necessary for peripheral membrane localization to the perivacuolar punctate structures.
Domain:
The PX domain binds phosphatidylinositol 3-phosphate which is necessary for peripheral membrane localization to the perivacuolar punctate structures.
Sequence:
MTDKGKNDLTSKAKDKARGNPEKPPYWFEIIVSDPQKRTGDPGSSSGYVSYQISTKTNNTSFYDNRGDPESIIVVHRRYSDLLLLHDILLNRFPTCIIPPLPDKKVFQYIAGDRFSQRFTQKRCHSLQNFLRRVSLHPDLSQSKVFKTFLVSKDWESHRKVLQDSLQPNKDEVTDAFMNAFKTVHKQNEEFTEIREKSDKLDRTVTKIDKLFHKVVKKNDSMSEDYTKLGSNLQELQELVTGENEELAAKLKIFNEGVTQLSYGLQDLTKYLDYEYIVDLKDLEHYIDSMRQLIKLKDQKQIDYEELSDYLTRSIKEKNNLISGYGGSNFFANKLEELAGINQEASRREKINKLEGKITSLTGELENAKKVADGFEQECLKEIDHFESVKTAEIKKSLGSLADHHIEFYERILEAWEKVDDSL
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MSAPESSPSTFYTVPTKHILSKAHLAAFQRSKTHSDIFNFIEELNEDIVGKKLTEAGQGSERTRPLISILDSVREIAESTPPVDNKLSRFGNPAFKTFYDKVGDASLELHKRIPGLPEEAIQEVEVYFKESWGNKQRVDYGSGMELNFLSWLLCLAKLGVVTKEDYPFLVLGVFWRYIEVMRYLQSTYWLEPAGSHGVWGLDDYHFLPFLWGSGQLRNHKYLRPKAIHDPEILGEFSKDYMYLSCIEFINSIKTASLRWHSPMLDDISAVKTWEKVNQGMKKMFVAEVLGKLPVMQHALFGSLLPFPTPEEDPELKRALEEEDGQSATDMHGHIHDPSEKGWSMDCCGIPVPSAFAAAQDANSHKGVPTLGNRPGIKPIPFD
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
MGDWSYDEATGPSTWPNHFPHCGGKMQSPININTEEAKYDGSLTDLDIKYPNTTDVLLVNHHGHAIEADILSSEPFVATGADLSSRYRLAQFHFHVGSSDIQGSEHHIHGVKYPLEMHLVHYNDKYPNASSAQGLLDGLAVISVLFESSSTDNPALNEIIDNLQNASYKDEEITVQNVPVGKIIPTDTEKFYRYNGSLTTPPCFETVKWIVLKKTASISEKQLRQFRSVFSTSRQATKPNSLVDNFRPTQSLNGRIIRKNFGKLLKYIIY
The following text describes a protein:
Function:
Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (By similarity).
Sequence:
MTVKTTVSTKDIDEAFLRLKDIVKETPLQLDHYLSQKYDCKVYLKREDLQWVRSFKLRGAYNAISVLSDEAKSKGITCASAGNHAQGVAYTAKKLNLNAVIFMPVTTPLQKVNQVKFFGNSNVEVVLTGDTFDHCLAEALTYTSEHQMNFIDPFNNVHTISGQGTLAKEMLEQAKSDNVNFDYLFAAIGGGGLISGISTYFKSYSPNTKIIGVEPSGASSMYESVVVNNQVITLPNIDKFVDGASVARVGDITFEIAKKNVDNYVQVDEGAVCSTILDMYSKQAIVAEPAGALSVSALENYKDHIKGKTVVCVISGGNNDINRMKEIEERSLLYEEMKHYFILNFPQRPGALREFVNDVLGPQDDITKFEYLKKSSQNTGTVIIGIQLKDHDDLIQLKQRVNHFDPSNIYINENKMLYSLLI
The following text describes a protein:
Function:
Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP. Affects motility, biofilm formation and virulence of this bacterium when there is a complete loss of phosphatidylcholine formation due to absence of both the synthase (pcs) and the methylation (pmtA) pathways.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MKIFNYKRVPYAEIRAFSVHILTASGSFLAFLGVVAASEHRFVDMFWWLGLALLVDGIDGPIARKVRVKEVLPNWSGDTLDNIIDYVTYVLLPAFALYQSGMIGEPLSFVAAGMIVVSSAIYYADMGMKTDEYFFSGFPVVWNMVVFTLFVMDASATTAMTVVTVSVFLTFLPINFLHPVRVKRLRPLNLLVVAIWCALGGYALLMHFETPTWAVIAFVASGIYLYCIGGILQFFPSLGAK
The following text describes a protein:
Function:
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
Subcellular Localization:
Cytoplasm.
Sequence:
MNSNANNTPIAIGISQVFPCSYLDGQQEQLLVIQEETLDPILFERLLAIGFRRSGSAIYKPRCPRCSACQPIRVPIQEFVPSKRQKRTLAHNRDLTWRITTEHTETQYALYEKYIRERHFDGPMYPPSKAQYEQFLFCHWLPPTFIEVYDDNRLVAVAVTDTLPNSFSAIYSYFDPDEERRSLGVLLILLQCRLAKLQGKAFLYLGYQIDANRKMSYKRLYRPYQILTHQGWEYSQVC
The following text describes a protein:
Function:
May act as a component of the cytoskeleton or as a chaperone for the reorganization of intermediate filament proteins during terminal differentiation in the lens. Does not seem to have enzymatic activity.
Sequence:
MDVQKIVSSFEADDIAFVRFEQTDLYGIARSRTIPARHFKEKAVKGLHFKGHLGYDPQTNFIGNSAYSAGVGKFDAVCFPDLDTYQVLPWSKRTARILIEPTYKGKLVEAQPRVVARRQLDKLTEMGYSLMSAHEHEFYLVEKESRKTIDDVVNVRSTVRLAACEDIVYTFLDGLAGVGVDVECAETEHSPGQLEITYKPAFGIRSADNAHTYKTGIKEMAVKNGFIATFMSKPYPDVSASGCHFCHSLWDSQGKTPLLYDASSHTGLTLVGEHWVAGLLEHTPAISLLMGPTINCLKRYLEAFTPSNATWGIDNRSCAVRVKLNGNEGTYLENRLGASGCNPYIALAAIVAAGMDGINRKLPLPPCVKDIDNAYNPVHIPPGTANVPTNMKEVMETLQMDDVITSALGEEFIDCFLAAKRHEILLQENNEENWEQNLFFETM
The following text describes a protein:
Function:
May play a role in mitochondrial aerobic respiration. May also regulate mitochondrial organization and fission; Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.
Subcellular Localization:
Mitochondrion.
Sequence:
MLQKLLRFLRMVLQQITYNMESALRSGKPYGSSRSIVRKIGSNLSLIQSPRVHFQLIPYPVEINAQNGNTIASFADVGWVAKDEGESFARLRSEIRPNQNTPVLPEPVPMEQPLIRQTSLPVLAEEEVKAQGVANKDAMQKISALESELANLRAQIAKIVTFQEQQSLTGSSTSTDSGSLSTPPPSAAPPPPPPPPPPPPPGLQKSVSAIDLIKERKGKKTSTDISLTDSAPKKPEMPSMLDVLKDMNRVKLRSVKRSPEEHKPSDPTDPATLIAEALKKKFAYRYRNDSESERTVSKAEHQHVPEVPLFGPHMLKSTGKMKTLIKASHS
The following text describes a protein:
Function:
Has a role in the regulation of vacuole fusion.
Subcellular Localization:
Vacuole membrane; Peripheral membrane protein.
Sequence:
MSIRFLKRLRAPLYIQNAYCSKNYFYRSFIQYYSPSNGPYLKISMNKAPQSLGLCTARGDSPTNQDRMAYGYLNNLKDTTNRDSPFFYGLFDGHGGTECSEFLSTNLGKIIENQDLNDTEKILKEVHSVGGYMAGLKPPFSLRTVLQSRDEDLLWRARLYYSFLQADMDYLTNYARPSPDSAVPGAVGTVAIITSKNNLSYWESDSYIIHLAHVGDTRALLCDSRTGRAHRLTFQHHPADVEEARRLRRYNMGFSRDSFGQKRFAWVANTRSFGDGYKLKKLGVVAEPQLTSIHSLRDDWSFLTLLSDGITDVVSDDEVVDIIKLSESPQDAANNIIRYAQNVGAVDDITCLVVRLPGWKKRTINDFTKNLRLEKSAYHPRRS
The following text describes a protein:
Function:
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
Sequence:
MDPGECTCMSGGICICGDNCKCTTCSCKTCRKSCCPCCPPGCAKCARGCICKGGSDKCSCCP
The following text describes a protein:
Function:
Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope.
Sequence:
MRGRLRWRIGGLQFPVRVGERVSFCPRSVPLQNVEHDTLSLQECLRSEELSLSRSLEILNQNLSLSASSALNSLEQAEAMSLRPTTRAEARKKSYKVAVDAEEARWRRENVLVEIRKSKREENLNKKRCEAGPHHLSPPPTHACGMKIDNLSEMAEGAYYEDPAVPSSVITQFRRLLSDGAPIEEVVKAGIVPRVVEFILRHETPLPQIKTALPVLQRLIHLNDEEVLVDACWAISHLSHGSKDRIQAVIEAGVCPKLVELLSHPSHKVLVPALRTLGNIVTGNDVQTQIMIKNLALPRLLQILTSSYDNYIKQEVCGVISNITAGNSNQIQAVIDANIVSPLVQLLQHAEFSVKKVAFWAISNAIHGGSNCQIQFLVSQGCIEPLCDLLAYPAPSINAICMECLDKILEVGEANKHLGITAGRNLYAQMICDCDGFNKIESLVAHDNIVIYKMAVNILKRFWVDDEEDMQDFD
The following text describes a protein:
Function:
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.
Subcellular Localization:
Secreted.
Sequence:
MAAYSLHKRRLATLNRDANAAWGAALQRSSNPSAPQDAFLDSANDGLPVAKRPLAANFIEPPVSIDAIRHDQATVKASATPNSAQADAAAATPTSTQPSIPNSKAGGPRNAFDILLRRQPPPASVVTPLRGSSASRRDKARERHRAPSTPARTTELVLDLGQRALNKTECSLCRMLYFPGQAADEKLHRSRHDAFVNGVKWRVAVDDERVLWGAEGGPGGALILGLTADQLTHSSKDDNIMMLATTRTLCLALAAAVLVAASADVTPWMNLQDDPESRAHALLAQMTLAEKVTMLHGHTEGNYSGNVPAITRLNIPALNLNDGPQGFRAPEKLSGTSTGFPSILTLGATWDPDMAAAYGTAIGEEFAGKGANVYLGPGLNVARVPLCGRNFEQVSPSPFPHHVLLSLVFITPCKPKMSLPMPSTGSTTTRFVAQESCRPKLFFVDNIFLGSESVHPKSKGVQRGQTLCPSQASGWLYDLIRHPLLPFQEINRDRVSANVDERTRFEMYYPPFEGAIKAGVGSIMCSYNRINHVYSCENNETLGIDLRQRLLGSQRAWVVSDWLATHSTSLVEGLDQEMPYGLFFDSLLELDLDLDLHNVTVAAIDNAVLNILTPMFAVGLFDHPLNGTVEANVTSPAHNTVARKVAAAATVLLKNDAGLLPLNATQPMTIGVFGIQGDAETWAHGGGSGSVTPPYIITPFQGVLDALGIQRPAGHTGQEDAPVGPFCNAHQQCVTYYEGQNDTITEALAEAVDVALVAVGTASGELLDRVHLGLGRGQDELTTLVASHNRNTVVHVTCPGAVLTPWRNDVSAILVGFMGGQELGHAMADVVFGHVNPSGRLPVTFPNVDNEVGFAERQYPGIEDHLQTYYDEGLEVGYRWYDAHGVTPAFPFGHGLSYTSFNYSDLTANSTGVSVRIANTGSVAGAEIVQLYLGFPSSAGEPPLQLKGFAKAMLAPGATTTVHLPLTDRDLSIWDVQDHAWSKVPGTFQVQIGSSSRDVRLAGSITVSQ
The following text describes a protein:
Function:
Might contribute to the loading of the ESCRT machinery.
Subcellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein.
Sequence:
MANDAAACAERATNDMLIGPDWAINIELCDLINMDPSQAKEAVKVLKKRLGSKNSKVQILALYALETLSKNCGENVYQLIIDRGLLNDMVKIVKKKPELNVREKILTLLDTWQEAFGGRGGRYPQYYNAYNDLRSAGIEFPPRTESSLSFFTPPQTQPDEDAAIQASLQGDDASSLSLEEIQSAEGSVDVLMDMLGAHDPGNPESLKEEVIVDLVEQCRTYQRRVMTLVNTTTDEELLCQGLALNDNLQHVLQRHDDIANVGSVPSNGRNTRAPPPVQIVDINHDDEDDESDDEFARLAHRSSTPTRRPVHGSDSGMVDILSGDVYKPQGNSSSQGVKKPPPPPPHTSSSSSSPVFDDASPQQSKSSEVIRNLPPPPSRHNQRQQFFEHHHSSSGSDSSYEGQTRNLSLTSSEPQKEEKPEDLLFKDLVEFAKTRSSKANNNNRSL
The following text describes a protein:
Function:
May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS.
Subcellular Localization:
Golgi apparatus membrane; Lipid-anchor.
Sequence:
MKVGGVCDRSWKAEEQEEAEEGAAAEGLRLCPLANLDSEMRPPQPPVASKVFVQRDYSSGTKCQFQTKFPPELENRLDRQQFEETVRTLNNLYAEAEKLGSQSYLEGCLACLTAYTIFLCMETHYEKGPAPSFQIPPSPPLLHHSFLLLPTPQCHLPQGLTLQSPFPWPGETCELVSIHFVSLGQASCVGVV
The following text describes a protein:
Function:
Involved in nuclear export, actin cytoskeleton organization and vesicular transport.
Subcellular Localization:
Nucleus.
Sequence:
MVKRAPEEREDVTMGGQEAPVDSDIIQVDFEFFDIKPIDFHASKNLLKQLFGYDHTFINLSAVSDFILGSAVAGSTVKVDGPESDPYAMLALLDVSANKAQEALSCIIKYLSDRSASANPELKNFFESSLADGSKEHVGLLLNERLINMPVQVIPPMYKMLFDELAQDKKGEFTHYILVSKTYTECTPQLDVDDDDAPRPTKKGKKLKKKKEKNSNEVFYFHPEDEILRQFATLAIDFPYVNQDFNPDANRVFQEAGIKPQGLAMVFTHDALSRLVPTLLQSFQA
The following text describes a protein:
Function:
Scaffolding protein that plays a role in ciliogenesis, cilium positioning and dendrite anchoring in sensory amphid neurons including AWB, AWA, AWC, ADL and ASI, the phasmid neurons PHA and PHB and the gas sensing neurons AQR, PQR, URX and BAG. Its role in cilium positioning may be through regulation of the localization of cell adhesion proteins such as the apical junction protein ajm-1, and the ciliary scaffolding protein Rootletin/che-10. Plays a more prominent role in regulating dendrite morphogenesis in AQR than in PQR neurons. Regulates localization of hmr-1 to the distal AQR dendrite. During embryonic elongation, required for the anchoring of URX and BAG dendrites to the presumptive nose.
Subcellular Localization:
[Isoform a]: Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Enriched at the proximal ends of centrioles. Localizes to the cilium basal body in AQR and PQR sensory neurons. Localizes to the cilium basal body in the outgrowing AQR dendrite. Localizes to puncta near dendrite contacts in the nose.
Domain:
The C-terminal domain is required for localization to the cilium basal body and role in ciliogenesis.
Sequence:
MKEKHENWSHPLAFWLCDCAAIIPNPATQNFAKNDFLDGLLMLNLMKFINPHFSENEKNGQSLYEELLNQISQFYEKNLDQVIVCKMPEISILESSGEIDEITFEELKKLLLLLLGCAIQSDHKKVFVDRITGFDQTIQAELAACIQKLTESDEIVQNLEDFERRKMKETDEVGGGGGSIEDVDSDDMESSTTSSSNGEIAIKQQDQSFLMSRSTSPTSELRHQTLQIANLQHEMRQMRTQAENRDEECQKLELDNEEKAQKIKILENERLKLVDFKKKWKSVNDDLQEANCKIEKLQNLVGIEKKYREARDGKELYKSKYDIVVKKNLEMEETITTLEKNLKTLQMEMKEKFGVEDNLQRMRNTIDDLEAEISKKNLEIEDFLDEKHRMDREIKELKEIVHQMEVPSTTTTPRIMDSLADQLENAKQDEFEMMKAEIRKLRAQTEGATPETTIIQCNQDLDTLRSQLSTEQHQTAQLHLEIQKMQVEKEQIDGNMERIGIELEEMSAQVENLNLERDEAVKQLLEARRKFGEFQMGQSRDLEEKWSKEVEKSNKISKKCEILEEKLQESDFLLAKSRDEAKKLQFELDEALEETSHVTRSLSSEKNTLKAKLLELQDQVEAQTLELLNQKNCGKRLEDRDQMISNLHNLKNELENDLKTCQTQLELESKKLQRLREDLVLEKSRRADLIGRIHSLCTTLSLNGANFEKINNDDELIDNIDDIMMNALVAVKRERDDLRIQGNQQIQELHDLKRDIEKLRRSESESLNESDDRVRELTRENMHTKEQVFMLQEKLRELNLELSTKNDEIDMVKASIEELNRNSTASCTSNAEIARLQVSIRNSQIQEDLVKQENTKLRDELQEMQKMSKKRSQNLDELENMHKTLLVDHSRLQQLHNLLTRDYDEAKKESMELRQKVQNIPRQQAVFMNANIRELEAKLSEEISRREQLEKEHKMCRIHCENLRRDITELVQTRDELSLELRRAHDTCHNKNNQIDELKKQLNQKISEVNKLSSKIEALSQLNRTYNEENRNLSRQLEILLTQNKELLQRALHDKDQYHLEMKDFQDQLSALRRHKEKLEDKIMDQYRTMENKKSTPERKQPLVKRAAKALINRRRATSNGGSTTEDSSVYSADERSSPPLAGTNEDVDHLPPTCSSSDDHDVISPDFSAKNPLLRSRNDFMGGSVRSPRRYGNDHDGHIYTSPFLPPRVPIRNSPMTSSLRSRPPPPPYNRSPAHKIEQNSSFFEPIAHSTPNSSILEERRVVGEGEKRELVRDKEERIDKTLSYYENVNLPQNPPDLPENSDLKPNESTIWHEYGCV
The following text describes a protein:
Function:
Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
Subcellular Localization:
Nucleus.
Sequence:
MNHNGNPIFCMDSHPKEPLVATGGGDGKIKIWNVRSLYEDNVEDIPKLQAVITLAHNVNCLRWSKDGKLLACGCDDSSVTIYKLSKVMDEGAFVNETLIFREYELVFILRGHNDSVTDLSFSYDGKQLATASLDCKVILWDIITGKQIGVLDHSLPVYGVAFDPLNILLFSQCSNAAIIWNVAKQQAEKKITEQFKLASHSNFFLRPSWSPEGTQLVMVGAISQKRYVACVTHREMNDVISFQGHKNEVVCCRFSPCLYKSVNFDGKKRAFSCFVIGGLDNSLSVWVARKQNQVCHFLNVFKGCIQDITWLPGGLRMMACSVDGFVAYFEFNENEIGGEVQGEEYLNKTIEKYMLNQQSIKEPLIPSGVKKQTTQTTLNFSGGKLTVERPVKKRVQPELVTEQPQKVELDEKSQLEKKLIEREKLEEKAKELIESERRSETRKSLVEESKIEREKMKERIKERWSEEEIKPRNERLSEKRKRDRKDEIPEDNEIKKKTWQLKELEICDSIKKSIMINKVMYDIIAERNNGEKIITTITEERHHDKKIIWSTIIPFKVRSIIATETHVLIVSEHVLYLLNVDTGIMETNPIVITFNLHKAFLDEKVILIDVMGNIQVLDKEFKKIYNGNIKELLTTFDCTEVTKAIVVKGVIQIEINGMFFAIDGDKFVLTSMGRIKPNSSSIEEKTILELNIRSQLKYGLQNSFDGLVNSFLSICNTSKDTIRIKALHDTLFELTKTLPNNSSLKNKFIGLTERITEIFITMKP
The following text describes a protein:
Function:
Key component of the Ran GTPase system, which comprises ran-1, ran-2 and ran-3 and is essential in nucleocytoplasmic transport. Promotes the exchange of Ran-bound GDP by GTP and regulates the onset of chromosome condensation in the S phase. Binds to the chromatin. RCC1 (ran-3)/RAN (ran-1) complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA.
Miscellaneous:
MISCELLANEOUS: Loss of ran-3 causes low levels of chromosomes to misalign on the metaphase plate and segregate incorrectly in early embryonic cell divisions.
Subcellular Localization:
Nucleus.
Sequence:
MSTAEQRMDTSEVELPNDNVNEQGNKTPRADQPESSASGARNHGEDEEVTEQVELAAMETEASDSIVDNVPKTPRRAGRPKKLPSTSTAAAESAVTPGKRGRKRKGSESVNTTINSTMNSTLNEPKTPGRKQAKLVAPLLTYDLFAPSIIGDRVLSCGEGEALGHPGRTTTKKPRKVDIFEEEGLKPLQAVAGGVHSAVLTSEGEVYMCGINEKGTVPAEGVEKEGSTDEFAKVKFEEDIEKEGKIVMLAAGASFTAALTDQGSVIAWGNLRNSNGNVDVHPLLHKMQEAPVVIVHQAKRKIVKIAAGENHLVMLDEKGCLLTFGDGEMGQLGRSSRTKTIRSKYMCDESGDHLLVPLRFKHKGKFFDVVAKNVFASGFWTIVHGEDGKYYAFGLNNYAQLGIKVDEADVGQDGQDNRELRVFLPAEAPAFGAERTFVNIEGVQHVVILGSDGKVFAMGKNTDNALGLGNWTGKDDQQHWLYDTIQEIEFDSKIVGVSAKLATSIAWSEDGTAYAWGFDTTGQLGLGLKDEDEKMVSKPEEISSAHLDGYSIIGASISDQHTLIIAKKN