lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Innate immunity protein that plays several important functions in antimicrobial and antitumor defense systems.
Sequence:
MLIFVSAYQRLRDTEPGAKTDTGALLCRCLTIMLRLLAIFATLCAVANSCPTILTKAQWGGRAATCRTAMTTPVPYVIIHHTAGAHCSSQTSCISQAKSIQNYHMNSNAWCDVGYSFLVGEDGNVYEGRGWNSVGAHAPNYNSNSIGISVMGTYTNINPNTAAQNAVKNLISCGVTKGYIKSTYILKGHRNVGSTECPGNTFYNTVKTWPRFQA
The following text describes a protein:
Function:
Transcription factor that acts as activator.
Subcellular Localization:
Nucleus.
Sequence:
MNLDGTSGGFPAEEDHHNEERQTKNKRKTKHRHKFSEELLQELKEIFGENCYPDYTTRKTLAIKFDCPVNVIDNWFQNKRARLPPAERRRIFVLQKKHDFPVQAHSFLSCQETQAAAHNYATKQSLSGAQRALMRRAGCSHLEKQWIPSQEMGYNCFSLENQETPSQQVGPQCSYLEKPGIPSQQVGSQCSYLEKLGIPSQQVASQSSYLVTGTEKHPGCAMGYGGDTGSGHSGSGHSTAYHFLSYNSAECLHPPPSSVPYFHGERTETKESQHASPFLLDYAQGAYGVKKDHCLCSFCLSLLGQQQQNDWQYHLQQHQQPQNYLEGMMLQEQLPMDSGPWDLGKQWSSAQSQLQSQLPQNNGKPLCSQLQHMSLQIAADSPLLPLGQDMQERASEQPRTQMQQL
The following text describes a protein:
Function:
Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP. Diphthamide biosynthesis consists in the conversion of an L-histidine residue in the translation elongation factor eEF-2 (EFT1 or EFT2) to diphthamide.
Miscellaneous:
MISCELLANEOUS: Present with 2270 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MKFIALISGGKDSFYNIFHCLKNNHELIALGNIYPKESEEQELDSFMFQTVGHDLIDYYSKCIGVPLFRRSILRNTSNNVELNYTATQDDEIEELFELLRTVKDKIPDLEAVSVGAILSSYQRTRVENVCSRLGLVVLSYLWQRDQAELMGEMCLMSKDVNNVENDTNSGNKFDARIIKVAAIGLNEKHLGMSLPMMQPVLQKLNQLYQVHICGEGGEFETMVLDAPFFQHGYLELIDIVKCSDGEVHNARLKVKFQPRNLSKSFLLNQLDQLPVPSIFGNNWQDLTQNLPKQQAKTGEQRFENHMSNALPQTTINKTNDKLYISNLQSRKSETVEKQSEDIFTELADILHSNQIPRNHILSASLLIRDMSNFGKINKIYNEFLDLSKYGPLPPSRACVGSKCLPEDCHVQLSVVVDVKNTGKEKINKNKGGLHVQGRSYWAPCNIGPYSQSTWLNDDANQVSFISGQIGLVPQSMEILGTPLTDQIVLALQHFDTLCETIGAQEKLLMTCYISDESVLDSVIKTWAFYCSNMNHRSDLWMDKSDDVEKCLVLVKISELPRGAVAEFGGVTCKRLIVDDNDSDKKEREENDDVSTVFQKLNLNIEGFHNTTVSAFGYNRNFITGFVDSREELELILEKTPKSAQITLYYNPKEIITFHHHIGYYPVEKLFDYRGKEHRFGLHIRS
The following text describes a protein:
Function:
Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
Sequence:
MNTFAEVQKLYREYYNFAIKNNILEIPEGIEYREFGYGYLKKVDNRNLSFKNEREYKDWVLKNAPMHFYKSLAYMLYPNKSGGASKKGIFRRELAFDIDVHKTKKCKHEDDWICKHCLEEAKNQAIYLIEEFLIPDFGLNEEDLKIVFSGNRGYHIYIKPRDEKIRDIIESYSKEDRRFLMDYILGKNLNLNSVGSGWRRRLIKAIKERDKRISTKKLENEKNWKKVIENLKSKNKIYNIIEETKNKIELDEKVMDDDIRLLRVINSLHGYTGFIVKPLSGLDELRRFNPLEDAIFKDFENKVYEVNIFDDRKFEIEICGKKYNNKSKKITASALLYLFGHNIKFELLKS
The following text describes a protein:
Function:
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Subcellular Localization:
Nucleus.
Sequence:
MSSLEELLSQVNSGAVNVNKSDATKRQQRKPKAQSDLQKKLRGQAGVVNNAAGAAAKPTAAERRSAAAASTRATPPPQPGGGGSVGGAGGSGTPGPSVGATAPGPGLGPSVGGTLPPAAPAVPPPLAADAPVPMRLKRVLDLLRSNRDTFTFADLKAKLNMDLSQDTELLEHLQSHTQVTYDGVDRTLRYRPKVQGISNSTDLLNYLRRHTTVEGASAAVPMTGVRLGDIADAYLNIADDIKRLQAEGSICVLGHTSAGSETLFAVQSMGMAPASEAVFELFHNTRLPVDMIDMQWRCKDLGLKSALASRPARIKDDSKDKKKKRKRTERRFNVEKATNAHMRELFEGAQPTNIDSK
The following text describes a protein:
Function:
Multifunctional actin-bundling protein. Plays a major role in regulating the organization, dimension, dynamics and signaling capacities of the actin filament-rich microvilli in the mechanosensory and chemosensory cells. Required for the assembly and stabilization of the stereociliary parallel actin bundles. Plays a crucial role in the formation and maintenance of inner ear hair cell stereocilia. Involved in the elongation of actin in stereocilia. In extrastriolar hair cells, required for targeting MYO3B to stereocilia tips, and for regulation of stereocilia diameter and staircase formation.
Subcellular Localization:
Cell projection, microvillus. Cell projection, stereocilium. Cytoplasm, cytoskeleton.
Sequence:
MALEKALQASRQGDLEALKALHRAGSLLPTLRDSLDALPVHHAARTGKLHCLRFLVEEANLPATARARNGATPAHDAAATGHLACLQWLLTQGGCGVEDKDNSGATVLHLAARFGHPEIVDWLLRYGESDPSSATDTGALPIHYAAAKGDFPSLRLLARHYPKGISAQTKNGATPLYLACQEGHLEVTQYLVQECEADPHTRASDGMTPLHAAAQMGHSPIIVWLVSCTDVSLSEQDDDGATAMHFAASRGHAKVLSWLLLHGGEITTDLWGGTPLHDAAENGELECCQILVVNGAELDIRDREGYTAADLSDYNGHSHCTRYLRTVENMSVEHRVLSRDPSGEPEGKQPDSGMSSPNTTMSAQPPHFDLCSPTSTLSNYDSCPSSRSSTRGHLGGPGPRLRNSTVTDMQTYMDMLNPEMGLHGRKKGGPTTPPPPPSFPPPPPPPGNQMPPPPPAYPAPKPPSGQHTADIYVQAKSKLRHVEREALRRELSSRDGHDGLRRVDSGRRSRSFGKQPSTGDYYRQLGYGPGEPLATSPGMAHSEEAALLSGSQVHNGSVADHRGARDLPPPPPPPPLPEALSSPPPAPPLPCEGSGPVCSQRRSSSSTGSTKSFNMMSPTGDNSELLAEIKAGKSLKPTPQSKGLTTVFSGSGQLPSLVRRGASSVQRLRPRSLGPSSRGPPSDHAFPFQTDAPPLSPSMPRARSPTPPASTIPGAGGGPHQPVLNGTVAPPLTPTQNLQLDVETLIPTHDEQGRPIPEWKRQVMVRKLQMKMQEEEEQRRKEEEEEARLAGMPAWRRDILRKKMEEEREQKRKEEEQLRQEAERREKEQSEKLRTLGYDETKLAPWQRQIILKKGDIAKH
The following text describes a protein:
Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Sequence:
MTKPTLTYFPVRGRVQFPRCLLEYLGEEYNFNEVKTISDDLRKQLLFKQLPLYQEGDFKIVQTPAIIDYISEKHDFRGKTKEERARAHQCLAGIMEVLDHCLGYSFKMDKQQQEKFRNESPIKKFFEGFEMVLSQNKYLASGEKETYVDLMAFVMVDYVTNLGLMPSGDYPKLISLKKHYESSPQLKKYLESRPQSNF
The following text describes a protein:
Function:
Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway. Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP). The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.
Sequence:
MSPFGTLPKGVRLIPYPTRSRTEPGQRNRQPTRSEIMKKLMNGAALALALAAGPALAADEVKLQLQWVTQAQFAGYYVALDKGFYDEEGLDVTILPGGPDIAPPQVLAGGGADAMLNWMPSALAAREKGLPVVNIAQPFKSSGLMLTCWKDTGITGPQDFKGKTIGVWFFGNEYPFLSWMSQEGISTDGGADGVTVLKQGFNVDPLLQRQADCISTMTYNEYGQVLDAGVSEDELVTFKYEDMGVATLEDGIYVLEDNLKDEAFKDKMTRFVRASMKGWKYAEANPDEAAGIVLDNDATGAQTEAHQVRMMGEIAKLTAGSNGALDPADFDRTVGTLLAGGSDPVITKTPEGAWTHEITDAALK
The following text describes a protein:
Function:
Pore-forming subunit of a voltage-gated ion channel.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MDSFKTVLKFFTDQKTTIGYSVMAILTIGSERIFSMVSFQCPCTKGQNFPYGICFLLGPAVVLLVVGFFVSTRFWRLYTGCCLNPLKLCPRGNFVGCLKGLIKVLYGACVAPVMWLTVALLNGTFYECAVSGLDEVAVIQIFCADKGSVCQDELHRVPCGKSTLPPEQNTELLYMLRAQSQILGWSVIITAVVIALIGTCYKNCVSQVSYLQLTFWKIYMEKEREKFDAFANDYATKLADRNLKSFFDNKLPEEFPFPNHKAWEEISAIYNFRKSEQHYSTLQRYVERSDRDYSPDEHPMVEMDHGIEMV
The following text describes a protein:
Function:
Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSETKNIESLILDAGPLITQPATTLQQYATAYYTTPGVHSELKDEYARQQLAIWGDSLKIKQPKQEYIDRVVKFAKLTGDYSVLSVNDLHIVALAYELECLNNGEDNLRSFPGEVLKNQQAENENGSNKMSNIIGDDDGFVVATKRRGGRRQREKAELRKKGLLPTFSPKPKGGSETEEPNESSNDKTIDETPQTDLIKGVDVQEQESQEEPVSESNTVGLDEITEEYNEDDDDGEWITPENLQEEIIKDKNEQVQESNTNGPLIKVALATGDFACQNVAMQIGIKLLNAMSGKQITRVRNYMYRCHACFRLTPMSKDGRPKHFCPKCGGNTLLRCAVSVDNKTGKITPHLKQNFQWIRRGERYSLPSPLSKNQKKLQGNGGYQHNKENRHKSLQTPLILNEDQKEYQRALKNDEWERKQQDKMLQEWIGGGSADNFVSPFGNTIRNSGVKVGRGRYANSSKKKRK
The following text describes a protein:
Function:
Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
Sequence:
PGNSDPSFSPSSSPLHFTSLHPAPAFAVFFPKLCPVANSHSATQPNAPPRRAERPTALRRGKSGGVPGGAVGSRKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA
The following text describes a protein:
Function:
Mitochondrial amino-acid transporter that mediates transport of serine into mitochondria.
Miscellaneous:
MISCELLANEOUS: Present with 9290 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion membrane; Multi-pass membrane protein.
Sequence:
MASSVPGPIDLPESRYDLSTYWGRIRHCAEISDPTMLLTTEKDLAHAREIISAYRHGELKETTPEFWRAKKQLDSTVHPDTGKTVLLPFRMSSNVLSNLVVTVGMLTPGLGTAGTVFWQWANQSLNVAVNSANANKSHPMSTSQLLTNYAAAVTASCGVALGLNNLVPRLKNISPHSKLILGRLVPFAAVVSAGIVNVFLMRGNEIRKGISVFDSNGDEVGKSKKAAFMAVGETALSRVINATPTMVIPPLILVRLQRGVLKGKSLGVQTLANLGLISVTMFSALPFALGIFPQRQAIHLNKLEPELHGKKDKDGKPIEKVYFNRGI
The following text describes a protein:
Function:
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MKRSGAYHSELDKDIVQKAGNFPLMQFKTKVKVNPKFLLKGDDMDIVDEAITYYKANVFYKNFDMSICEADKLLVYLIFYIQSLLLKFNGHTKVECDKMAYSLAIENFALPGDGKFCLGGIVEPLKASEKEVVRQYMTAIRNETGLRLTQAVFKNDPTKCDKWWMCFNKRKFLNKTI
The following text describes a protein:
Function:
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Modulates plant growth and development.
Subcellular Localization:
Cytoplasm.
Sequence:
MEVGVELWRTRRLLGDLSEMQGNGTSMITLMVPPRDQVARVQKLLVEEMGAAANIKSRTNRQSVQGAIKSAQQRLKLYSKVPPRGLAIFVGTIALGGNKDRMIAVSFEPAKPLSRFAYLCDKRFHTELLDFLLEESETNVDLPKKHGRGGQSALRFDRLRTGCRHNYLVQASEAAVKHFIDPSSSQANVAGLILAGSADLKTELEPLLDPRLRAKVLKVVTISHGGERGFNQAIELSEDVLASVKFVQEKKLLGEFFEEIGVCSNKHVSGIRDTLQALEMGAVKSLIVYEDLETRRYVYDDPQTGNKVTKVLSKEEAKEEVPRNREVEDKALVEWLAEEYKGFGCELHIITNHTEEGSSFCSGYGGIGGILRYPLDFAAMNEEGDEA
The following text describes a protein:
Function:
Glutamate-gated receptor that probably acts as non-selective cation channel.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MRSATTHDVFSLLLVYFLLIYQMANNKNGVNGSVNDDCNIIWRIGAIIDPISRLGKEQKVAIEMAVHEFNGQNSKCSELVFDFAYYSHGSSSPAASIATYLVNKKQVHAILGPLTQQEAVLFSEFDESYKGIPIISLSPTATYSPQLVSPKDPPSSLVQISDDVKSQMQCIAALIGHFKWRKVIALYESTNSFSNMDSGLITHFSDSLKVVGSTVEYHLAFPPLLSLSNSKSFTKEELEKLKTKNVKVFVVVQCSLDFGLVLFEMATEMGMMGKDYVWIISDNMASFFDSVEPSVLLNMQGVIGFKSNVDDKSESFKQFNAKFRRKYRSEYPEEEEGNPSPSFYALKAYDATWATAKAMQKLTKNNSSELVKTILSSDFEGLSGKVSFKNGVIFQKPIFKIINVIGKSYREVSFWSPEFGFFNDLVEYNGMKLKIGNGLGGDLESILWPGGQQKVPKGWTIGGLEKPLKIGVPAKGAFNQFVTVNFNQERNETIIGGFSVHVFEAVVRQLPYYLPYVLVPFYGTYDEMVVGVSNKNLDAAVGDTEIMADRYEYAEFSQPYIDSGLVMIVTERPILKKPRFIVIKAFKLKLWILLAVMSMSTGVVIWLNEYVNNNPDFSGSFPQLIGSMLWFSVTVLSFSQRESIRSNLSRLVLTTWLCVVVVITACFTAVLSSIMTVPRLEPSILDVDYLIRTNAAVGCNGNSFIVRYLVNLRFKPENIKKISSISDYPEAFKKGEISAAFFVAPHAKVFLSKYCKGYTKSGPVFKLGGFGFVFPKGSPLAVDISEAVLKVSQSGEINQLEEQMLISSNCSSSSAKEQDPGLGPELFSGPLLISGVICGIVLLISIARLVKRHWLILSSIIASNAAMVSRWVSLALTQCYSILGIKFCKVSSPVIDQRSNNQQNGEIAEVF
The following text describes a protein:
Function:
Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
Subcellular Localization:
Golgi apparatus, cis-Golgi network membrane; Single-pass type IV membrane protein. Golgi apparatus membrane. Endoplasmic reticulum membrane. Note=Concentrated most in the intermediate compartment/cis-Golgi network and the cis-Golgi cisternae 1 and 2. Greatly reduced in concentration at the trans end of the Golgi apparatus.
Sequence:
MEAQYQSTNFLLQKVQHDLGRLEGTQNEQDAQVVVQSIYGDISTLKDNLQALDNYVSREQPARRQAARMRVDQLRMDVQRVDMAVSAVHTRMTQRWRSASEREELLSARYRPNDTALSIGDHELQLNDRLHSSHNRLDELISQGSAVLDNLKSQHFSLRGVSRKMHDIGQALGLSNSTLQVIDRRVREDWIFVIGCIVCCIFMYAFYRFWRG
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MASNLLKALIRSQILPSSRRNFSVATTQLGIPTDDLVGNHTAKWMQDRSKKSPMELISEVPPIKVDGRIVACEGDTNPALGHPIEFICLDLNEPAICKYCGLRYVQDHHH
The following text describes a protein:
Function:
Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
Sequence:
MTEPLQIFGWRDAIDIAIVAWIIYRLIIMLRGRVANRLLLVLAFLAALYSLSRLAGFEAFHWIVGSLFSSLILILVILFQHDIRRALVTHGKHRHALTEDRDEQEERDHASLIVGELIAAATSLSSRRIGALIVIEREMGVMSHVETGTEVDAKITSEILTSIFLPYSPIHDGAVIIRRGKLTRAGCFLPLSQDPTINKNLGTRHRAALGLTELVDCVVLVVSEETGTISVAVGGRIISVSDAASLRKILKKLLEPRWLTE
The following text describes a protein:
Function:
Putative transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MSTNLEMEPRARDSPAEPILANNHTDQAAYQIPAYPNHPTSPSGGQGGSRTSPIAAAPPALPHGYNHQTPTGPHEAHLHPELRTHESGPTNGYQPVPGMMPVGVPPQPEQQGAMPAPSTPVGVSQMGIVSPGDSAGDGRKSKRELSQSKRAAQNRAAQRAFRQRKEGYIKKLEQQVRDYSEMEMSFKALQNENFALRDYILHLQNRLIDVQGDYPQPPPNISLATPHTQQLQQQQPPPPPSVPHGIAPDPVQAVQQVPPATSAPSASLEEAAQAVAGLSRSDHHMGGTSRDPYNTAVSAAAAAAAAAAAAAASRTDDDARTAEVIQRQLQADNNSGMSDGLPLQQAAI
The following text describes a protein:
Function:
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Sequence:
MVHKVSQREFSRCYKRNCDCICRKPKQRRNVYLNYSLELLITIFKEVIPNLPMDKKIAFVKDYGAYLKVEKGLITCKIKNQVKWSIAPTELHSIVVLTNSSISSEVVKVANEYGIEIVFFNKHEPYAKLIPAKYAGSFKVWLKQLTAWKRRKVEFAKAFIYGKVHNQWVTLRYYERKYGYNLTSQELDRLAREITFVNTAEEVMQKEAEAAKVYWRGVKSLLPKSLGFKGRMKRVSDNLDPFNRALNIGYGMLRKVVWGAVISVGLNPYIGFLHKFRSGRISLVFDLMEEFRSPFVDRKLIGLARESADKVTDLKTVYSLFSDVKEDEIYTQARRLVNAILNDEEYRPYLAK
The following text describes a protein:
Function:
Catalyzes several different glutathione-dependent reactions. Catalyzes the glutathione-dependent reduction of lipid hydroperoxides, such as 5-HPETE. Has glutathione transferase activity, toward xenobiotic electrophiles, such as 1-chloro-2, 4-dinitrobenzene (CDNB). Catalyzes also the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4 (LTC4). Involved in oxidative DNA damage induced by ER stress and anticancer agents by activating LTC4 biosynthetic machinery in nonimmune cells.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.
Sequence:
MAGDSSLLAAVSLLSACQQSYFALQVGRVRLKYKIAPPAVTGSLEFERIFRAQQNSLEFYSVFIISLWMAGWYFNQGSLVSG
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MELANKFFSKLFGEKVGEDEFGNIFYKSNRFSRYFSRDMRWVIYNGIPEATKISANWYSWLHHQDDKLPIKNTKTLYKWVKPRTPNLSGSELSYYPPGHFFSNDKSSDHKLDKNDQYIINAIFDNIDGIKLGSGVKVSGVVIGKVTSQRLDYDTYSAEVQMLINKKIKLPEDSSAQIVSSSILGDKYISITPVQKTQLVKYTIIIFIYLTFIFNCNQYISAFEEIENENAESPFSVLDEDIYKSTNSDLDITKQSIIQGELESFNLAKIRILDYNTGHSSNKELKLEENLELTEGLFVNLKECKKDIKDTLNPVSMAFISVTNHDKIIYEGWIFSKNTSIALPKIDDGLIYLTSCDNQVINEEEVNK
The following text describes a protein:
Function:
DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
Subcellular Localization:
Nucleus.
Sequence:
MSTPTVDASGASTRTAIRYQDSIGSLSRSEKSVQRILSQSTRIHVLRDKLDERSVEELEASAQQLGAQLTTSAESANIVVTAIKAPKRILKWIPDGEANVVPPRTERGETGRAREEVQRVERQLGEEVLRDWRRFVVTPQWLDAVKAEARLVDPDLFAVVAIKDESKTLESKPSATSDRKRKHSPSGSPLLAPSHHASPPAVLRRKHLSSSPTPTTASSSYYDAIYPPAPCPRWQNTRYACRRPSPLHSPNQALITELELIRTERRLTGDTYSEMAYMRAISALKAFPFPIPDRILDPPEVFDPALLELRLSEVEKLKGVGKKVFSLIKQFYASENKSGERIVEAKVIARDPAVYIMNAFTELYGIGPIGAREAYNSGARSFSDVLHRGKSLATHLSVQESVRILADLRKPIGREECRSITAHIMALVRSMLADDVEVKYEICGGYRRGKESTYDVDIIIGHSEPPSRALHMRLLNEMKRKGLITHLVNVSTPASSYLDPDTTIHDKHTPPPVHIDIANIVVLPPLSDRTHLAMHRRVDLVFCPLRVYGATVLGWTGSMTFERDLRLWAKSKGFNFSFDGLTNLADESLVDTTDEKAVFDALDLQYMPPEWRNCDA
The following text describes a protein:
Function:
Pseudouridine synthase that catalyzes pseudouridylation of mRNAs.
Sequence:
MYCRYTNKNIFTEKGVILPLVRSLSGEFVHQSHLRRLVLYSKVDIQNRKGIQAHRFCLVRNLVHQDHIMPKRKSKNSNHPQKIKKFAHEQQFEGVEYYFENGLRKIKPYVYKFECYAKGRWFGSKLLDVFKKEFRLESAEYYETAIHEGLIRVNKGKASPDLILKNNDFMQSKVHRHEPPVSGEPIQVIADTQDYLVINKPSSIPVHPCGKYRHNTIVFILGKDYGFKGLHTIHRLDRLTSGLLLFARTLQVSHRLDAYVRERKLEKTYVCKAHGEFPSTPVVCEEPIFIVSHKIGVCRVKEDGKPCKTRFERLSYDGETSIIKCHPHTGRMHQIRVHLQYLGFPIINDPLYNNTVWGQHRGRGGNNQLTDEQLLKDLIDQHDIDIDSALEKARLQALINKPKVTSHIDTARPEDASLTPGSQEPSKDAVINTKDVRTSGTFIPSTNESDQVHLSVASITHCATTTEELGEDTAVEITSNSHVECSPLGDPPATVSSSMGVTDEVTKACPSDKDDKGIVGNGRTSINSSSMGNSNIFGNPGMVERSHDKTRTSTEEVCRSMSSATSDAMKDKDDDAVREVQDVESTETRTFSDVGNIKDDCNEESLIDERTDKLAVSLCRECRDPMPDPEPDEMLIYLHALTYKGPDFEFSAPMPAWAQEHFERTGTKYS
The following text describes a protein:
Function:
GTPase-activating protein for the ADP ribosylation factor family.
Subcellular Localization:
Cytoplasm. Golgi apparatus.
Sequence:
MINSKSKKKESNALVLKSLLREPYNKVCADCKRNEQPRWASWNLGVFICIRCSGVHRSLGVHVSRVKSVDLDSWTDEQTENMTRWGNERANLYWEAKLAGGHVPSDSKIATFIKTKYEFKKWVLYPEIPSPETLKPEQNTRPVSEVNASLDLNTASRSSSAHSVKSTSSATVTNVTSKKEAISATTSLAQSSPNLASLSKQPSTVHAPSTRQRDLKSSILSLYASPRPQVSSSSITTNATYQNLPSPVSTSTTSSQPYGAFHQPATTGSSFVADKWKMPMFTSNVTSAQPSARASPVQSNSSRPRSSLDSKIINSHDVWK
The following text describes a protein:
Function:
A flexible structure which links the flagellar filament to the drive apparatus in the basal body.
Subcellular Localization:
Bacterial flagellum basal body.
Sequence:
MGLQSALTTALTGLSAAETQIDVIGNNLANAQTVGFKSSDAVFATQFLQTLSLGAGPSANNGGTNPRQIGLGVQVAEIAANHNQGTIEISSSSSDLAIQGDGFFQVQAADGEKLYTRNGIFKLNSDAELVNATGQRLLGYGIDEQFRLQTDSLVPLSVPLGTKTVAKATENVSFEGTLTPEGDVATAGQVIESLHLGDSQVPRPDASGVSIESSPIADHTSVTGTVGAGSLPAGTYQYKFALVDASGNESAPSAARAFTVGANGNVDLGNLPQDPLGGDFPTVNIYRTGPNGTEFEYLASAAAGGTFNDDGSTALSGTPINEDTLTGNYTYMVTYYSSGDPESRPSSFLGPKSVVDGRITLSDFPTPPTPPAGGGFPAYDSIRIYRNLAGDQNNFYLVGEVAPGDTFTDSATDAEISDLTDPGNQLLDMDGPAVNSNTLLTDVLRRDGLTYEQVFSEGTLSYTGRKGGANLGTKELEITSTSTMQDLLDFISDASGIQTLQVDSSNPIPRSDNNITGESGDLVAGAYIQDGKIRLVSNNGEANAVDIELSAFRLTDELGQISTPNLAFGTLQEAIGQSASSDFVVYDSLGVPINVRVSATLESRTDQATIYRWYADSPDNSVSGSTDITVGTGLIQFDGNGNFVTATEETISINRQGLPSVSPMQFEMDFSLVSGLATDEATLAATQQDGSEPGVLNSFIVGEDGTIRGVFSNGISRDLGQLQLARFANPAGLEARGLNLYAEGVNTGLPVTGQPGENGIGTVIGGALELSNTDIGKDLVELVLASTQYRGNSRVITTTQQLIDELLNLRR
The following text describes a protein:
Function:
Component of the CUL4-RBX1-DDB1-DCAF1 E3 ubiquitin-protein ligase complex, DCAF1 may function as the substrate recognition module within this complex. Appears to be required for plant embryogenesis and to affect several other developmental processes including leaf, shoot, and flower development.
Subcellular Localization:
Nucleus.
Domain:
The DWD boxes are required for interaction with DDB1A.
Sequence:
MDGQEHAEVPNSMVEDDQSVVAAEAIAELANSTGEPNPEEGEEQSVEDELIAKAQKLMEDITSVANNPNPNILHALSQLLESQESLFLEENGHFSNARGSHNSGKLCILIRENDEFFELISSTFLSENSYSTAVKAASARLLMNCSLTWMYPHVFDDAVTENFKNWVMEEAVKFPGEDSAKKEASDFEMLKTYSTGLLALSLASRGQIVEDVLTSGLSAKLMHYLRVRVLKEPSTSRIHTTETKHVSLKTKEEGRSRVRKIVDTVEGDHVLETDSGREMGQTDVQPDGEFEIDGRDVFNVSGVVDCKIKPGDDNSVRDDPSRHRLNRSKSRGRGRVHEGAPDTEVLLASPRLGRLLVRDRDLSKISDGRNAEDVTVCLGKMKSGIMEIEREDNDECFQGCIIGTKNITDLVKRAVGAAETEARAAHAPDDAAKAAGDAAAELVKTAALEEFKSSGSEEAAVSAATRAAITVIDAAEVSRNPTCVTSDQTTDVSEVSLPDIESLAQLQEKYCIQCLEILGEYVEVLGPVLHEKGVDVCIVLLERTSQLDDRSTVSPLLPDVMKLICALAAHRKFAAMFVERRGILKLLAVPRVSETFYGLSSCLYTIGSLQGIMERVCALPLVVIHQVVKLAIELLDCSQDQARKNSALFFAAAFVFRAILDAFDAQDSLQKLLAILKDAASVRTGANTDRSAPEVMTSSEKQMAFHTCFALRQYFRAHLLLLVDSIRPSRISRGGVPSSMKPNIRAAYKPLDISNEAVDAIFLQLQKDRRLGPTFVKAQWPAVNNFLASSGHVTMLELCQTPPVDRYLHDLLQYAFGVLHIVTSIPDGRKAIAHATLSNNRAGIAVILDAANISNSIVDPEIIQPALNVLINLVCPPPSLSNKPPLAQNHQPVPGQATTRPSTDVAVGTQSTGNAPQTPVAPASSGLVGDRRIFLGAGTGSAGLAAKLEQVYRQAREAVRGNDGIKILLKLLQPRIYVNPPATPDCLRALACRVLLGLARDDTIAQILTKLEVGKSLSELIRDSGGQSSGTDQGRWQAELAQVALELIGIVTNSGHATTLTASDAATPTLRRIERAAIAAATPITYDSKELLLLIHEHLQASGLGDTASALLKEAQLTPLPSSASPSSIAYSTTQEMSTPLAQEQWPSGRANSGFFTSKPKVCAHDEDPNSRSNAALSAKKKHLASSTLEMPTPVAQQQWPSGRANCGFCPSIPKINARDEDPSSRGNAAPSAKKKQLTFSPSFSSQSRKQSFSHDALPQSTQRINCCSNSDPALADTSETAAELVLKNDLDADAQFKTPISFPRKRKLSELRDSSVPGKRIDLGERRNSTFADGSGLQTPASALDANQSGSSRLGQMTPASQLRLPSDPQPSNPERLSLDSLVVQYLKHQHRQCLAPITTLPPVSLLHPHVCPEPKRLLEAPLNMTGRLGTRELQSFYSGVHGNRRDRQFVFSRFKSWRSFRDETALFTCIALLGGTNHIAVGSHAGEIKIFEASSGSMLESVSGHQAPVTLVQPYVSRDTQLLLSSSSSDVQLWDASSITGGPRHSFDGCKAAKFSNSGLQFAALSCEASRKDVLLYDVQTCSPCQKLTDTVTSSRSNPYSLVHFSPCDTLILWNGVLWDRRIPEKVRRFDQFTDYGGGGFHPSRNEVIINSEIWDMRTFKLLRSVPSLDQTAITFNSRGDVIYAMLRRNIEDVMSAVHTRRVKHPLFAAFRTLDAINYSDIATIPVDRCLLDFATEPTDSFLGLITMEDQEDMFSSARMYEIGRRRPTDDDSDPDDDDETEDEDEDDEEEDDLDRILGLAGDNSDSGDDDLSSEDNEDSVSDFDEEADILIDGDFMEELIEGENEDDGNGEDEDDDDDGEMQDFMSSGEEDDYRDNIRSS
The following text describes a protein:
Function:
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
Sequence:
MRMAESNKLKTGIFSGSFNPVHIGHLALANYLCEYEELDEVWFMVSPQNPLKAGTELWPDDLRLRLVELATEEYPRFRSSDFEFHLPRPSYSVHTLEKLHETYPERDFYLIIGSDNWARFDRWYQSERIIKENRILIYPRPGFPVNENGLPETVRLVHSPTFEISSTFIRQALDEKKDVRYFLHPKVWEYIREYIRQSITDN
The following text describes a protein:
Function:
Component of a carbamoyltransferase involved in the anaerobic nitrogen utilization via the assimilation of allantoin. Catalyzes the conversion of oxalurate (N-carbamoyl-2-oxoglycine) to oxamate and carbamoyl phosphate.
Miscellaneous:
MISCELLANEOUS: Oxalurate could not be used as a standard substance due to its unavailability, and the enzyme reaction was performed in the reverse direction: the synthesis of oxalurate from oxamate and carbamoyl phosphate; MISCELLANEOUS: Multicopy suppressor of dominant negative ftsH mutations.
Sequence:
MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ
The following text describes a protein:
Function:
Metalloprotease.
Subcellular Localization:
Secreted.
Sequence:
MIFLLFVVFPFVYAQLLPELLAGFQNGRFRGGPDGFNRGPGGFHRGPDGFGGDPRGGVDLGHLIGNIAANVGQEMGLNDADVIGDLRGISRGPRPSSMEWGRRARHFCRRYPGHPKCQRGQLPQFTDVPTIINTIIYNAGDLLPRVPTLNIHDPLAGLNSELVGFIKSLQSQFGQLSSQQRNEIHDSCRSFKCDQQSPQNTQAKQELLTKMLAFDQAVGGKAAPAHDKVNLRFDRTQQVKQALLKRANLSHIIVPADNGVFDRDVLLTEHQANFLLNELGEAGRGADVGAGGGGGGRVPRSGVFFQESAVQKWDIWKPIQYTLDDSLEESDKKDIRDALHEISINTCILFRYNATPKGYHLNYMKVDSTTFCGLSYVGRTDPANPIYLSFQCGDNRGVAMHETMHALGVSHQHLRLDRDKYIKIDWSNIDPQHYDTFAISDAKLYTSYGTKYAYDSIMHYNAYLGAKDPNKPTMIPLVNPQENTPKLGQRAKLTRGDIRLLKKMYCRPGCDDQNVHCGTWALHGYCKMKEQMKWMNENCKASCDKC