lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
The CERK1, MEKK1a/b, MKK1a/b/c and MPK4a/b proteins are involved in pathogen defense. The pathway induces rapid growth inhibition, cell wall depositions and accumulation of defense-related transcripts. This protein is required for full defense response to fungal pathogen chitin.
Sequence:
MSRRVRRGGLRVAVPKQETPVSKFLTASGTFQDDDIKLNHTGLRVVSSEPNLPTQTQSSSPDGQLSIADLELVRFLGKGAGGTVQLVRHKWTNVNYALKAIQMNINETVRKQIVQELKINQVTHQQCPYIVECFHSFYHNGVISMILEYMDRGSLSDIIKQQKQIPEPYLAVIASQVLKGLEYLHQVRHIIHRDIKPSNLLINHKGEVKISDFGVSAVLVHSLAQRDTFVGTCTYMSPERLQGRSYAYDSDLWSLGLTLLECALGTFPYKPAGMEEGWQNFFILMECIVNQPPAAASPDKFSPEFCSFIESCIRKCPSERPSTTDLLKHPFLQKYNEEEYHLSKIL
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MPLAFYGTTNNDTGTLHFQYLEVIIRTMDSPLNLRPRPPNSRGPQTIADFIRRVNAEPGGFRALNEEEVRRNVIAERNGLHHEDVEMVTDQEADDDSKKPDIIAARHNIIMSLGQAIQISSNFLDFISLLLSKEIPTQAAVSISPWLRSQVPIGSIGATQLDAPTPLTQSRVADNKLITIGKRLVALNEAADTALAAANRLRQEINSETKYWQEVLTVSQKGWSTARLPQEPHDMGVKFGFSNAAPLFKNNSVAPLKRAEDGSVRLEYGRMGSKSERLQATLLHNGEVVGRSSLPRPLPDDAPLDDRVKEARNTIFAQELWHEINREGRTLHGHHVRLEQSAVTCALDPNRTISFELVGLDDQDHSRAPLPGDLDAETASITLHLLLSNAHRQNQLKRSERTAANAMRGPPPPYNLLLPIITYYRHEKTLEDCTTFLAAFCGALRSAGIQSSFSMTESINKGPPTAPPSEALMKTLLHPSEVQFDLTITPASRVRILAKPTPVFGTRFSIYLLHPQSNHLTSSFPPNQTDSVYENIKELVRYLSNAVPRALTMYYYPLVQEMRNSGNKGNNGETPNPPAPNTTTWIIHPDDLGLVDDDTETFGVRFAFTSNYTRGDEVGDAAKEPELRVTGDYMEDGKRVQHEWKWTASGPAGTQSGGSLDEIVKHILANGPSSSVLSA
The following text describes a protein:
Function:
Self-assembles to form a helical, filamentous nucleocapsid mesuring 1980 nm in length and 24 nm in width. Together with capsid protein 1, wraps arounds the DNA and maintains it in an A-form. Capsid proteins probably maintain the DNA in A-form by non-specific desolvation and specific coordination of the DNA phosphate groups by positively charged residues. This certainly protects the viral DNA under conditions such as the extreme desiccation of its host.
Subcellular Localization:
Virion.
Domain:
The N-terminus projects into a DNA groove.
Sequence:
MARRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQRQSGAGLGVTSGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK
The following text describes a protein:
Function:
May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.
Subcellular Localization:
Nucleus.
Sequence:
MGKGTDKLYITHSEWSSSDAFGSARGANTSTRNSATGLSSTFKRLPFNYCAVSLQPFTDPVCTESGTIFDLTHILTWLSKHPGTSPIDGSSLKRDDLITLNFTKNEDNEYVDPVTYKVFTDNTHIVALKKSGNVFAWDTIERLNIKAKNWQDLVSDEAFTRKDIITLQDPQNIESRDFGSFKHVKEGDTVMPDSESSVNKEALGNAAKILKAKEAVAKARADRQAKAQGAQSSKALTSTTKNGKTAGASNEPKKPAYNAAVYTSGKAAASFTSTGVTPHTSNALAILSDEDYMLKPKRVKIKGYARISTNLGDLNIELLPEFAPRAVWNFVKLAQKGYYRNTVFHRNIKGFMIQGGDPTGTGRGGQSIWGKPFNDEFDGPERHSQRGVLSMANKGKNTNTSQFFITYRAVPHLDRKHTIFAKVVGGLDTTLKAMELTEVGEKDKPVDDIEIQDIVVFVDPFEEWQKERKDKEAKDVEAEEIKRQGGTADDKTTWTGKRIRADGTVDNSSGDGLGVGKYLQAAKQEVQDMGDDEIVGYVDEEEDVAPAKKKIKSSGFSNFDAW
The following text describes a protein:
Function:
This transmembrane glycoprotein is involved in the control of cholesterol biosynthesis. It is the rate-limiting enzyme of sterol biosynthesis.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MLSRLFLAQGRFCSSHPWEVIVCTLTLTICMLSMNYFTGLPRICGWNYECAPQVKESSLSSDVLVMCIMRTLAVAYLYLQFTKLRTTGSKYILGIAGLFTIFSSFLFSSAVIHLFGLELTGLNEALPFFLLLIDLTKASALTKFALSSTTQNEVVDNIARGMAILGPTITLDTVVTTLVISIGTMSSIRKMEVFCCFGILSLIANYFVFMTFFPACLSLVLELSNSNKYGRPVWHLGRFAEVLEEEEDRKPNPVVQRVKMIMRTGLVLVHAHSYWLASNDTELMSRDMLYDGNLLTDKKIDPTMPLWEFYATRLWPPTLDYILTAILATVLASHYIFFSDLATYPEKRVSIMEGHEVVNPGSDHEDASEVETIGTLSSSPSTSDVRVIESMTSRTQACQTDPVTASPRNSRSSSPVSSHSVKPARFTIGSSGSGSEDEEEEVIKEEEVEWVLETELKAPRPMPELLEILNVGKGPNALTDDEVQLLVGAKHIPAYKLENILDNPERGVAVRRQIISKLLPITDALEKLPYASYDYSFVSGACCENVIGYMPVPVGVAGPLLLDGQEFQVPMATTEGCLVASTNRGCRALRSAGGIHSVLIGDGMTRGPLVRLPSAQEAGAIKQWLEVPENFAAIKERFESTSRFAKLKSIQTALAGRYMFLRFKALTGDAMGMNMISKGTEQALHALQTMFPNIEIMSLSGNYCTDKKVAAINWIEGRGKSVVCEATVPAHIVQQVLKTSASALVDLNIHKNLVGSAMAGSIGGFNAHAANIVTAIYIATGQDAAQNIASSNCMTLMETRGPKGGDLYLSCTMPSIELGTVGGGTVLPPQSACLQMMDVKGSNIHGSGLNASQLARIVCATVMAGELSLMSALAAGHLVKSHMKHNRSALNIASPLPSIDEVATHRRSKSVDFSALKESSAAAPGTCTANAS
The following text describes a protein:
Function:
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein.
Sequence:
MPSSASGSAPATFLHKVIAAVSIAALVHAGYSAAQHRLYLRLTEQPFTALPADIVAQTLASLIFLCWAYTHVAGAFQPIRADIANGRRKWDDVGSCLSFATFEHRAKALSPTYAFDSGRSVSILLLLF
The following text describes a protein:
Function:
Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. Required for developmental angiogenesis. In this process, required for microtubule reorganization and for efficient endothelial cell elongation. In quiescent endothelial cells, triggers rearrangement of the actin cytoskeleton, but does not alter microtubule alignement.
Subcellular Localization:
Cytoplasm. Cell membrane; Lipid-anchor. Note=Enriched in lamellipodia.
Domain:
The DAD domain regulates activation via by an autoinhibitory interaction with the GBD/FH3 domain. This autoinhibition is released upon competitive binding of an activated GTPase. The release of DAD allows the FH2 domain to then nucleate and elongate nonbranched actin filaments (By similarity).
Sequence:
MGNLESTDGGPGEPPSVPLLLPPGKTPMPEPCELEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPNVTRKKFRRRVQESTKVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQPPNALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSNQVHTLRRLIKEKEEAFQRRCHLEPSARGLESMGGEALARVGPTELTEGIPPSDLDLLAPAPPTEETLPLPPPPAPPLPPPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQINGTVFSELDDEKILEDLDLDRFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPELANFWQELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTARTAKRGSRFFCDAAHHDESNC
The following text describes a protein:
Function:
Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MKQKTSLPTAFMAGAFSGTCSTILFQPLDLVKTRLQTRAIASGNGGMFYTFYTVFRADHVAGLWRGLTPSIYRCVPGVAMYFTSLHGLSSFVSEDPSPLQSIVLGATARTIAGVCMMPVTVVKTRYESGNFNYTSMRQALVSIWTNEGGRGLYSGLVATVARDAPFSGLYLMFYTQIKRRAKGLLQVGDLTSGQNFICGIMAGAMASVVTQPADVVKTRLQMNPYMYPSNRAAVVAIIEAGGIEGLFRGLVPRTVRRTLMSAMAWTIYEEVSRYFGLRKHK
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MASTITGSQDCIVNHRGEVDGEPELDISPCQQWGEASSPISRNRDSVMTLQSDYLENIESETYLPLKVSSQIDTQDSSVKFCKNEPQDHQESRRLFVMEESTERKVIKGESCSENLQVKLVSDGQELASPLLNGEATCQNGQLKESLDPIDCHFKDIHGWKSQVVSCSQQRAHTEEKPCDHNNCGKILNTSPDGHPYEKIHTAEKQYECSQCGKNFSQSSELLLHQRDHTEEKPYKCEQCGKGFTRSSSLLIHQAVHTDEKPYKCDKCGKGFTRSSSLLIHHAVHTGEKPYKCDKCGKGFSQSSKLHIHQRVHTGEKPYECEECGMSFSQRSNLHIHQRVHTGERPYKCGECGKGFSQSTVMLLAYGDKEKKEPIWHQAQKCLVPWKMGVRCEEKAMKLMAICIWNIPPHYINTHCSPTPVRG
The following text describes a protein:
Function:
General aromatic amino acid transaminase involved in several otherwise unrelated metabolic pathways. Responsible for phenylalanine and tyrosine biosynthesis. Active with glutamate, phenylalanine, tyrosine and tryptophan as amino donors and with phenylpyruvate, hydroxyphenylpyruvate, 2-oxoglutarate and pyruvate as amino acceptors. Also active with methionine, alpha-aminoadipate and leucine as amino donors when phenylpyruvate is the amino acceptor and in the reverse reactions with the corresponding oxo acids and phenylalanine as amino donor. Catalyzes the formation of methionine from 2-keto-4-methylthiobutyrate (KMTB) in the methionine salvage pathway primarily using aromatic amino acids (tyrosine, phenylalanine and tryptophan) as the amino donors. Catalyzes the formation of alpha-aminoadipate from alpha-ketoadipate in the lysine biosyntheic pathway.
Miscellaneous:
MISCELLANEOUS: Present with 1770 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MTLPESKDFSYLFSDETNARKPSPLKTCIHLFQDPNIIFLGGGLPLKDYFPWDNLSVDSPKPPFPQGIGAPIDEQNCIKYTVNKDYADKSANPSNDIPLSRALQYGFSAGQPELLNFIRDHTKIIHDLKYKDWDVLATAGNTNAWESTLRVFCNRGDVILVEAHSFSSSLASAEAQGVITFPVPIDADGIIPEKLAKVMENWTPGAPKPKLLYTIPTGQNPTGTSIADHRKEAIYKIAQKYDFLIVEDEPYYFLQMNPYIKDLKEREKAQSSPKQDHDEFLKSLANTFLSLDTEGRVIRMDSFSKVLAPGTRLGWITGSSKILKPYLSLHEMTIQAPAGFTQVLVNATLSRWGQKGYLDWLLGLRHEYTLKRDCAIDALYKYLPQSDAFVINPPIAGMFFTVNIDASVHPEFKTKYNSDPYQLEQSLYHKVVERGVLVVPGSWFKSEGETEPPQPAESKEVSNPNIIFFRGTYAAVSPEKLTEGLKRLGDTLYEEFGISK
The following text describes a protein:
Function:
RNA helicase that plays an essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes. Involved in spliceosome assembly, activation and disassembly.
Subcellular Localization:
Nucleus.
Sequence:
MAHLGGGAEAHARFKQYEYRANSSLVLTTDTRPRDTHEPTGEPESLWGRIDPRRFGDRVDHGKPPELLEKKAKASKRKEKENQDDVLRRPSKRSKGSQEESVLSLQEEGTYRPKTKETRAAYEALLSTIQQQFGDQPQDVLRGAADEVLVVLKNDKMKDSDKKKELEKLLNELGQERFNQLVNIGKIIVDFYDGGDAGGAAGEALDDDIGVAVEFEEEDEEEESDVDEVQEESENEEDGQETNEASAMQMGGLDDEDMEEADEGLNVQDIDAYWLQRKITQAYEEIEPQHSQKLAEEVLQTLGEGDERDVENRLVMLLDYDKFGLIKLLLKNRWKIVWCTRLARSQDDKERKRIEDEMTEGGSVLSGILEQLHATRATAKERQKNLERSIREEARKLREEGGDGEKDRRPEREVVLEGGWQGQRQFLDLKDLAFEKEGLFMANKKCELPEGTYRTMKKGYEEVHVPAMKVKPMEEGEELVKISDLPSWAQPAFKEMKTLNRIQSRVYETALFTQENILLCAPTGAGKTNVALLTILQELGSKQESDGTFDLSHTKIVYIAPMKALVAEMVGNLQKRLADYGVVVKELTGDQSLSRQQIEETHIIVATPEKWDIITRKSGDRAYTQLVKLVIIDEIHLLHDGRGPVLESIVARTLRQVETTHDMIRLVGLSATLPNYVDVSMFLRVDKSRGLFHFDNSFRPVPLSQQYVGISVKKPLQRFQLMNEICYEKVLAVAGKSQILIFVHSRKETAKTAKAIRDSALTNDTLGKFLKGDSASSEILRTEAENVKNTDLKGLLSYGFAIHHAGMARADRTLVEELFADGHIQVLVSTATLAWGVNLPAHTVIIKGTQVYNPEKGAWTELSPMDVMQMLGRAGRPQFDSTGEGIIITGHSELSYYLSLMNQQLPIESQFISKLPDNLNAEIVLGSVQNAREACAWLGYTYLYIRMLRNPLLYGVNPEVLETDETLEERRADLIHTAATILDKNNLVKYDRKSGYFQVTDLGRIASHYYISHGTMATYNEHLKPTMGEIELCRLFSQSEEFKNVGVREEEKLELAKLLDRVPVPVKESLEEPSAKINVLLQAYISQLKLEGFSLFTDMTFITQSAGRLMRALFEIVLKRGWAQLAEKALNLCKMVQRRMWSTQTPLRQFKGIPIDVLTKIEKKDYAWERYYDLTSQEIGELIRIPKLGKMIHKFVHQFPKLELSAHVQPITRSVLKVDLTITPDFQWDEKIHGFVEPFWVIVEDNDGETILHHEYFLLKMQYVEDDHNLSFTVPIFEPMPPQYFIRVISDRWLKAETVLPVSFRHLILPEKYPPPTELLDLQPLPVTALREPSFEALYQQFKHFNPIQTQVFTVLYNTDDNVLVAAPTGSGKTICGEFAVLRMLQKNADTGGGKCVYIAPKEALAKERFEDWEKKFADLKVQVVQLTGETAMDLKLLDRGQVIISTPERWDVLSRRWKQRKQIGQVNLFLVDELHLIGGEGGPVLEVIVSRMRYISKQAGDKIRIVALSASLANAKDLGDWIGASSHGLFNFSPAVRPVPLEIHIQGVDITNFEARVQAMTKPTFTAILQHAKGGKPALVFVPTRKHARSTASDLVLYALAGGNSFLQCTEKDLEPLLERIRDPELKETLQGGVGYLHEGLSPTEQDIVGELFSAGAIQVCVASSSMCWGMTLTAHLLVVMGTQYYDGRENAHTDYPITDLLQMMGRASRPLVDSSGKCVILCHAPRKEYYKKFLYEPFPVESHLDHYIHDHLNAEIVVHTIENKQDAVDYLTWTLMYRRLTQNPNYYNLQGVSHRHLSDHLSELVESTLNDLESSKCIAVEDDMELSPLNLGMIASYYYIRYTTIELFSNSLTAKTKMKGLLEILASASEYATLPVRPGEEDIVRKLVNHQRFSVDKPKYSDPHLKANALLQAHFSRHPVPGNLAMDQREVLLQAIKLLQAMVDVIASNAWLNPALAAMEISQMVTQGLWERDSVLLQLPHFTKDLAKKCKERNVETVFDLLEMEDGERRELLGMDDSQLLAIARTCNRFPNIDMAFEVLDEAEATVGEPVAVQVTLEREVEGNEEVGIVEAPRLAKTREEGWWLVLGDTANNVLLAIKRVTLQRRNKCKLEFTPQEAGVKNYKLYFMCDAYLGCDQEYDVTIDVKEAAGGGEAGEVRAMEE
The following text describes a protein:
Function:
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSAKNPWFWLAAILAIALDRLTKVWVVAQLAPGESIALWPGVFHLTLVKNSGAAFSLFAGGSDWLKWISLLVSVGLCVYALVGPHLGSWEQMGFGLLLGGAVGNGFDRFAFGEVTDFLDFRLIQFPVFNGADIAINLGLACLLIGTLRSESRTPAPARPASKQIREPTDTTGG
The following text describes a protein:
Function:
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Miscellaneous:
MISCELLANEOUS: Present with 6490 molecules/cell in log phase SD medium; MISCELLANEOUS: There are 2 genes for uS14 in yeast.
Subcellular Localization:
Cytoplasm.
Sequence:
MAHENVWFSHPRRYGKGSRQCRVCSSHTGLIRKYGLNICRQCFREKANDIGFNKFR
The following text describes a protein:
Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Subcellular Localization:
Endoplasmic reticulum membrane. Microsome membrane. Membrane.
Sequence:
MGLLSGDTLGPLAVALLIFLLLLDLMHRRSRWAPRYPPGPMPLPVLGNLLQVDFEDPRPSFNQLRRRFGNVFSLQQVWTPVVVLNGLAAVREALVYRSQDTADRPPQALYKHLGFGPRAEGVILARYGNAWREQRRFSLSTLRNFGLGKKSLEQWVTEEASCLCAAFADQAGHPFSPMDLLNKAVSNVIASLTFGCRFEYNDPRIVKLLDVMEDGLKEEMKIMRQVVEAVPVLLSIPGLAAKVVPGQKAFMTLVDELIAEQKMTRDPTQPPRHLTDAFLDEVKEAKGNPESSFSDENLRLVVADLFSAGMVTTSTTLAWALLLMILHPDVQRRVQQEIDEVIGQVRRPEMGDQALMPFTVAVVHEVQRFADIVPLGLPHMTSRDIEVQGFHIPKGTTLITNLSSVLKDETVWEKPFRFHPEHFLDAQGRFVKQEAFIPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPAGQPRPSDHGVFVALVTPAPYQLCAVPR
The following text describes a protein:
Function:
Plays a role in septum formation. Has no chitin synthase activity.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Note=Septum.
Sequence:
MSFQNPSYINAKHRSFLQPKDTQDSQDLRNWVSHSSVDEETAYSSSTLSSSSSKSFPCYDEYDEIKSPDDQKVEYMKTLRTLEEDAFSYTDSVYDFEERSFDEHEPPIPPLHKTGVFSVPLQPTHTVNSNSDDGYENSSKNEYLDFNSEISASPVNEPMTHSQSYTSIDRLNSSSSHYSKDVPLLCGSLTIDCPTPIDLRGMLGPFMQKNPDEASFLRYSAITCQPEDMNNNGLQLRTWSTGRDIQIAVCLTLSDEDLASFAISLSSIMNNLKHLCSRSKSRVWGNESWEKVLVCVVIDGRNTVHQNVLDLLASIGVYQPHIAKGRVNGKRTLSHMYEFTSTINVDEKLNLTTATGDGNVPMQMLLCVKDRRLGTYNSHRWFLNGIASLARPKVCLFVRNGARLGPTSIYHAWKAFDVDSTIGGMCGKTSIDTGKFGFRLLNPFIASQHFDQMIHNNLRLPYDSCMGYISNALNAIYGFRYVALQDSYPNPGPLADYFEQDQYEIPRRGILQSNAFLAQEQLLFWKVITRKDAKWHLQYVPEACATIEAPNSMAGILESKKSEINSSFSLAVYVIVDFFSLWTTRHKFFRFLLLTVQSLVFAIEKLVNFFSMANFFLAFYFVCNATSYSSLNPYGNWARPLFLVFEYILICLIFSQFMLAMGNRPRSCRVLLFISTALFSIIMIYFVFCVFYISLIPLHNSDNSEIVLGNNYFTTLIFSSLLILACYAFVSLICMDPFFIFTCIVQYILLMPTRIYTEQIYALCHLDDASISKDDNQQEFNFDTGITHCSMNDEGYTTISIPKANVLNSVYNSSLKNFSSSNDTSVYHDVQDHCYRKPQSYEDHYQDIRTRYVLVWAVSNLILAIVLIQVFDGMRFINNGYMKYIFWSIVAFTAWKTMGAVTFIATKIISRIANCVKSKLYIFNDP
The following text describes a protein:
Function:
t-SNARE involved in diverse vesicle trafficking and membrane fusion processes, including cell plate formation. May function in the secretory pathway.
Subcellular Localization:
Membrane. Note=Plasma membrane, some endomembrane compartment and cell plate in dividing cells.
Sequence:
MFGLRKSPANLPKHNSVDLKSSKPNPFDSDDESDNKHTLNPSKRTTSEPSLADMTNPFGGERVQKGDSSSSKQSLFSNSKYQYKNNFRDSGGIENQSVQELEGYAVYKAEETTKSVQGCLKVAEDIRSDATRTLVMLHDQGEQITRTHHKAVEIDHDLSRGEKLLGSLGGMFSKTWKPKKTRPINGPVVTRDDSPTRRVNHLEKREKLGLNSAPRGQSRTREPLPESADAYQRVEMEKAKQDDGLSDLSDILGELKNMAVDMGSEIEKQNKGLDHLHDDVDELNFRVQQSNQRGRRLLGK
The following text describes a protein:
Function:
Involved in the biosynthesis of pyridine alkaloid natural products, leading mainly to the production of anabasine, anatabine, nicotine and nornicotine, effective deterrents against herbivores with antiparasitic and pesticide properties (neurotoxins); nornicotine serves as the precursor in the synthesis of the carcinogen compound N'-nitrosonornicotine (NNN) (By similarity). Catalyzes a late oxidation step subsequent to the pyridine ring condensation reaction in the biosynthesis of alkaloids (By similarity).
Subcellular Localization:
Vacuole.
Sequence:
MKRNISMFLQLLLIILMMISFLFTSLLVPSVSATTLNTISTCLINYKVSNFSVYPTRNHAGNSYYNLLDFSIQNLRFAACSKPKPTVIIVPESKEQLVSSVLCCRQGSYEIRVRCGGHSYEGTSSVSFDGSPFVVIDLMKLDGVSVDVDSETAWVQGGATLGQTYYAISRASNVHGFSAGSCPTVGVGGHISGGGYGFLSRKYGLAADNVVDALLVDAEGRLLDRKAMGEEIFWAIRGGGGGIWGIIYAWKIRLLKVPKTVTSFIIPRPGSKRYVSQLVHKWQLVAPKLEDEFYLSISMSSPSKGNIPIEINAQFSGFYLGTKTEAISILNEAFSELGVLEGDCKEMSWIESTLFFSELDDVANSSDVSRLKERYFENKSYFKAKSDYVKTPISVGGIMTALNVLEKEPNGHVILDPYGGAMQRISEEAIAFPHRKGNLFGIQYLVVWKEKDNNNIVKSNIGYIEWIREFYNTMAPHVSSSPRAAYVNYMDLDLGVMDDYLLPCTSTTASANHAVERARVWGEKYFLNNYDRLVKAKTKIDPLNVFRHQQGIPPLFASMQEYTYSSK
The following text describes a protein:
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Localization:
Nucleus.
Sequence:
RHNQTGVLFCSAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEEKEEEEKEENKD
The following text describes a protein:
Function:
Transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MLFSSTGTMAFAAPETNSVDFRNHEAANDDLPSSFPSHVFPSSCPPHQEFQGISPLLMRRAMSFDHNQESRVEDDMSDDDGSSHLLGEKKRRLNLEQVKALERSFEMGNKLEPERKMQLARALGLKPRQIAIWFQNRRARCKTKQLEKDYEILKRQCDKLKADNDALKTQNKKLHSELQLLSLGNRESAGGTPPMLFNLNKENEGCNWNNNGSGDENNSTIDVNLGTTTRTSSTNSPLNNHDVFPTAYKVDQTVNEEGFCNMFTNVEDQTNFWPLPVQQHFY
The following text describes a protein:
Function:
Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytosol.
Sequence:
MSVSIVVEYCEPCGFKSHYEELASAVLEEFPDVTIDSRPGGTGAFEIEINGQLVFSKLELGGFPYAKDLIEAIRKASNGEPVEKITNSQAPCVIL
The following text describes a protein:
Function:
Probably lacks tyrosine-protein kinase activity.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Domain:
The protein kinase domain is predicted to be catalytically inactive.
Sequence:
MECGSHSGHRPIPIWLSSCLVAMCLGLPLGAAVPQEAPAYYYVGCYTARTDLLHESVYAKTPQTCIEICEHQGHHYAVLASEKCFCANVLEPQEQQDEQLCNTRCLANKAQYCGGVGVHSYYSTILTKQPGPHHLRISNKTENSLTLSWNAYEARKLLLAGGAEAVLPNQLLDNFLIKAQVLKTYSSLPAFPQPEFMVQSTETQFELTDLHPATLYNISVRAMCKDAQVGQSECGQASIEATTEVGLPSPVPAQPKILSRTDRTVTIELSPIRNDNGPLSKLLVIVEYVDNALSQPFDAQLLGSWQQAQQDGVPYYIAAELDYDRPEDNRTRRFVVGDGKRYGRFTNKPLDQPDAHVHISLGLVSTLEGVTKTMYSRGTHDQHVTSLDDFSYATFEKGQSSVVALAVTCVIFGSCLLLSLIAYFYLRYKTCRGRRLTGGNTHEMTLQTPIIERENNGYLVEDDPLPHSPENFKQQLQQLVEGYERIPRNALRLNVNDVIGDGRFGEIITGKVSTNDFARDCTLHVLCLDDLNGTTQAQLLRELRQLSQLKRQEHLLDFYGVSASPDWFYLIFEQQRMSLKRKLVESRLMAPSPRLTSLSEQLVLQWIYELASAMNYLSSCQVVHRQLCSHSVFVTSDFKLKLSVFGPLPYMNIARQQPDHNRWLAPEVLRHQHHHSTRSDVWSLACVAWECCALGGTPYANAVASNQQLLEAIRAAVRPAQPAYVYGDLYQLLLNCWQLEPSERSSCEDVAFGVRQLMTSPRHALSFDRVAGGLDTLPPYLPQLEAVATMG
The following text describes a protein:
Function:
Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.
Subcellular Localization:
Peroxisome membrane.
Sequence:
MGSLPSNRDSLVSSAVGFLQDPTVASSPLAKRIAFLESKGLTSSEIEEALRRASSLSTSQNAFAAGYRGPYQADRDATDWRDWFVMTVIGGGVGYLLINLAKKFLLPALKPPTQTELEEAQARLEQKYDEVSGILQTIQADTEIVKREITEQTEKLGLAMKEVESAVEECLTGEIKRDQELHSVQQEVEGLRTSVQQMFQSNKEAQTAAIVDLQTELKSLKSLMTARPGPSSNLPASSTNGVSVRSPQTPSGLNSFGIQPQASSLSKFNTTRPVGIPAWQLAPGYNTTLANQTSNNGDHSSNQTGSTPTPSASGSSPQTKTLSYSNGNGTGNLDDHNRSGTATPELSSSRQSLVEDDDDHIINSKYTTDSQNQSINEPMKASVDGLLS
The following text describes a protein:
Function:
Functions as an E3 ubiquitin ligase (By similarity). Involved in the age-dependent pseudo-self-compatibility process.
Sequence:
MAFDLPNDFRCPISLEIMSDPVILQSGHTFDRVSIQQWIDSGNRTCPITKLPLSETPYLIPNHALRSLILNFAHVSLKESSRPRTQQEHSHSQSQALISTLVSQSSSNASKLESLTRLVRLTKRDSSIRRKVTESGAVRAALDCVDSCNQVLQEKSLSLLLNLSLEDDNKVGLVADGVIRRIVTVLRVGSPDCKAIAATLLTSLAVVEVNKATIGSYPDAISALVSLLRVGNDRERKESATALYALCSFPDNRKRVVDCGSVPILVEAADSGLERAVEVLGLLVKCRGGREEMSKVSGFVEVLVNVLRNGNLKGIQYSLFILNCLCCCSGEIVDEVKREGVVEICFGFEDNESEKIRRNATILVHTLLGIPMSS
The following text describes a protein:
Function:
Intracellular storage of molybdenum. Binds polyoxomolybdates. Can bind at least 90 molybdenum atoms per protein molecule.
Subcellular Localization:
Cytoplasm.
Sequence:
MTDTTNSIKHVISPLARQTLQDRDLTRPVAGKRPIRLLPWLQVVKIGGRVMDRGADAILPLVEELRKLLPEHRLLILTGAGVRARHVFSVGLDLGLPVGSLAPLAASEAGQNGHILAAMLASEGVSYVEHPTVADQLAIHLSATRAVVGSAFPPYHHHEFPGSRIPPHRADTGAFLLADAFGAAGLTIVENVDGIYTADPNGPDRGQARFLPETSATDLAKSEGPLPVDRALLDVMATARHIERVQVVNGLVPGRLTAALRGEHVGTLIRTGVRPA
The following text describes a protein:
Function:
Transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) complex and plays a key role in repressing rDNA transcription. The sumoylated form modulates the stability of the NoRC complex component BAZ2A/TIP5 by controlling its USP21-mediated deubiquitination (By similarity). Binds to unmethylated major satellite DNA and is involved in the recruitment of the Polycomb repressive complex 2 (PRC2) to major satellites. Stimulates the ERCC6L translocase and ATPase activities (By similarity).
Subcellular Localization:
Nucleus. Nucleus, nucleolus. Note=In the nucleus, observed in heterochromatic foci containing CBX1, CBX3, CBX5 and histone H3 trimethylated at 'Lys-9'. Released from chromatin during decondensation. Association with heterochromatin does not depend on sumoylation.
Domain:
The BEN domain 4 is necessary and sufficient for the localization of BEND3 to heterochromatic regions.
Sequence:
MNSTEISEDVEEVLKNNPVKAEGSDATLDCSRNSRASEKHLLESVLTALHDSSKRKQLDSDGQPDSVPSVKRRRLIPEALLAGMRTRENSSPCQGNGEPASRGRSGSCAWPAEEEPSTEATVPSYKKPLYGISHKIMEKKNPPSGDLLSPYELFEKANSSSGPSPLRLLSESQKRECGVGVATDGDLNIYFLIQKMFYMLNGLTTNMSQLHSKMDLLSLEVSRVKKQVSPSELVAKFQPPPEYQLTASELKQIAEQSLSCGDLACRLLLQLFPELFSDVDFSRGCSACGFAAKRKLESLHLQLIRNYVEVYYPNVKDTAVWQAECLPQLNDFFSRFWAQREMEDSQPGGQVTNFFEADQVDAGHFLDNKDQEEALSLDRSSTIASDHVVDTQDLTEFLDEASSPGEFAVFLLHRLFPELFDHRKLGEQYSCYGDGGKQELDPQRLQIIRNYTEIYFPDMQEEEAWLQQCAQRINDELEGLGLEGGSEGEAPRDDCYDSSSLPDDISVVKVEDNFEGERPGRRSKKIWLVPIDFDKLEIPQPDFEMPGSDCLLSKEQLRSIYESSLSIGNFASRLLVHLFPELFTHENLRKQYNCSGSLGKKQLDPARIRLIRHYVQLLYPRAKNDRVWTLEFVGKLDERCRRRDTEQRRSYQQQRKVHVPGPECRDLASYAINPERFREEFEGPPLPPERSSKDFCKIPLDELVVPSPDFPVPSPYLLSDKEVREIVQQSLSVGNFAARLLVRLFPELFTTENLRLQYNHSGACNKKQLDPTRLRLIRHYVEAVYPVEKMEEVWHYECIPSIDERCRRPNRKKCDILKKAKKVEK