lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MFKEERRHAIINLLIKDNSVSVSKLSDLYKVSQETIRSDLRYFQKSGMLQRCYGGGILNRDALSKLITENKIDISSTIATPIHQDAKLRRENPKKAGKVCVLGSFNIDVSATVPWFPQSGESILASQFGFYPGGKGANQALAANNAGAAAHFIFKVGKDQFSAFAMNHIIQSGITSYSAYQTDKAPTGSALIYVSAVDGDNIIAIYPGANMMLTTQEINEQHRYIAESDVMLMQLETNIEALTEFIRLGKQENKMIMLNPAPYTKQVTHLLSDIDIITPNETEASFLSGVTITDINDAKKAGNIILQSGVKKVIITLGARGSLICEHARTLYIPAWSAVVKDAAGAGDAFNGALAAALARQADMVAAIQYASAFASLAVEQVGASSMPQHLQVLHRMRTQSNKVIHIN
The following text describes a protein:
Function:
May play a role in cell protection during the inflammatory response. In epithelial cells, negatively regulates IL6 production and apoptosis through the regulation of MT2A expression.
Sequence:
MKFGCLSFRQPYAGFVLNGIKTVETRWRPLLSSQRNCTIAVHIAHRDWEGDAWRELLVERLGMTPAQIQALLRKGEKFGRGVIAGLVDIGETLQCPEDLTPDEVVELENQAVLTNLKQKYLTVISNPRWLLEPIPRKGGKDVFQVDIPEHLIPLGHEV
The following text describes a protein:
Function:
Involved in pre-mRNA splicing.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MPPSSLAEYLAKKYLTADPATDRPKKKRKKTKTVDTAGDGLIIADDDPPDLRTSATNFDNEDDEGPSLVTSVRSAEFRRAKKSNWRTVGGPATGSSNANDERDAADAILASAAAESAARRGEGEGGDDEAPAVVDEADADDGGELRMESGARAGLQTAEQTAAMVAAQERRKKAEAARHRERPAEAQETIYRDASGRIINVALKRAEARRAEQEKREKEEAAKEALMGDVQRAEREARRQQIQEARAMPLARTIEDDALNEELKAQQRWNDPAAGFLTKTKGPGVSVTGKPLYKGAFQPNRYGIRPGHRWDGVDRGNGFEKEWFAARNKKGRLEALDYQWQMDE
The following text describes a protein:
Function:
Bifunctional nuclease with both RNase and DNase activities. Involved in basal defense response. Participates in abscisic acid-derived callose deposition following infection by a necrotrophic pathogen.
Sequence:
MDLLKQGSFRKGSAGSVTATGAVALGCGRVAGGRPRVHNPLLGCNSALHMPTLMSCASQQLHSTMRAALLAASGDAGRTGEVEQLHRHTAVPCETSRMLNPQAASRRGLLLGSATIAAAALTPWLGLDTGDAQAAAAAGALLHSRRSDVPCSLTIRNRSAMVVEARWVNYDGDEEPYATIPPGHEWTVDTFETHPWRFRDARTGGLVVEYVAARGPRLLQLTDTGAAEAEPAGSSAQGRGARQSQASDSPATRTGSGSPHAMDDVYADEDGSSEGAVTALQPEPPATGLAGGFDGLGHLQAEYTLATLLSVGILTREEQALLVLGLEAYPHPLTLLVGLLEAGSVIDAAGGSRGRRPSMLATWANTLQALGGKVERVVITRQVGGIFYARIVLSQPEQPQQSQPRGLGRPGAGSASSTGGRRIVSVDARPSDALSLALEAGVDVFVSRPVAQLVQRQYEDAERELPDLLLPPPEGGPPGLGLDEAGQYAAGRQLRSGAGQLAGEAMSA
The following text describes a protein:
Function:
Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin-catalyzed premature activation of zymogens; In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production.
Subcellular Localization:
Secreted.
Sequence:
MKVAVIFLLSALALLSLAGNTFSAKVTGKEASCHDAVAGCPRIYDPVCGTDGITYANECVLCFENRKRIEPVLIRKGGPC
The following text describes a protein:
Function:
Required for the export of polyadenylated mRNAs from the nucleu; binds to polyadenylated mRNA, and is involved in the regulation of mRNA polyadenylation.
Subcellular Localization:
Nucleus.
Domain:
The C-terminal region is required for nuclear mRNA export.
Sequence:
MLPHISADEAQPSMSRKVYINPNFQLQGQTAHQLPFQVPFQAFQAPLQPQPAIHINPHFLNRQRAMYDQYQREQQEQLMMQQVSASHYRLDPTIHLLATPPPPPAKIISKVSTCLVRKPSVVASGPAVKLAASVPVPTVSSLVQPPLVSISKRKIVRQGALKAAPAVAALHPPPPAKRTRYKLVRSISLTCTPLVKKRRPLREFVGQYALRRTNEAQPNRKLSSKPQALKLGVNKSLSMVSIHGVMYKKISKNKITKLDASSSARVAKSESPRTLQRTLSGRTLFVSGNKFILDPSGCRLTRVSTSSTGATQSSVNRSILRRIDIGGLTYVASPKALNVFVRTSNHVSRAHLITAKQRSLTLLNKSLVKTNVPCAIFQKLGKCVAHSRGKCRKLHDKRQVAICVSFLRGECTKPKCLLSHNVTLEKMPVCRYYLRGVCVREDCPYLHKKLSSKTEICIDFVRGYCPLAAECNKRHEFSCPELERKGKCELPRCVFCKKSPSKRLAKVKSRPKLGSKPVAFTDTAKESSTADELPTSSRYFGSHKEPAEAILTRDDVEQKKPEAEDEDQKEAGAPCPRRRPQLGTLPSFIPLGGEEKL
The following text describes a protein:
Function:
Responsible for synthesis of pseudouridine from uracil.
Sequence:
MSILLQTEKADEGKRLDIFISDKLNISRAKAQEAIEKKFVKVNNYVKTKSYKIKFNDLIEVSDEFSLKLENSEKLIPQNIPIQVIYKDDYLIVLSKPAGMVVYPCAGHPDGTLMNALAYHVKKLANVGAPFRPGIVHRLDKDTSGVMVVALDDETYYKLVEAFKKREIKKEYLALVYGQLRGSGKITTPVGRAIYDRKKMSIKSKKAKEAITEWEVIKNFKNYTFLKVKILTGRTHQIRVHFSSIGHPVIGDKTYGRKTYIEIGNKKIPVSRQMLHAHKIELIHPITEKLLQFEASLPDDIQYILNILEDRYESE
The following text describes a protein:
Function:
3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'.
Subcellular Localization:
Cytoplasm. Cytoplasm, P-body.
Sequence:
MRGGSGVVESSVIVERVDDVDKEKKKKRRSNRRSKHNSAFNSVNEARGETSDSMKSDDKTKNLVSSMGYSSSKQGLEMTSNEQTASNVGFSSMPTMHINERFGSACDDTAVDVGGSTYSKSCPESIAYPGSSKLCTDGFLPFHQFEGSSRKKLFAPYWPMEAVNEALEKGEAFKALFRVNAHNRLEAYCKIDGVPTDVLVNGMCSQNRAVEGDIVVIKVDPLGLWTKMKGSNGSSNNSTVVEDCNLVQEVNGLADNSEKGKGKVDANCEHRDGRSGVLPDRGFYDATQVTRTAAYNHVNGHHQYGSESLHVGLLPGQNEGMNSVDQLASMTIRYPLKRPTAKVVAIVEKSLRRNAIVGFLNVKQWFSYLELNRKDAKKNSVILDHEYVTFSPTDPRFPKMVVFVRDLPVSIKKRLEDGDITIEMELLAAQIEDWSAESSFPCARVSHSFGRGSDLEPQINAILYENAIPCADFSPQVLSCLPSTPWEIPSKEIQTRRDLRDLCVFTIDPPTASDLDDALSVEKLSKDTFRVGVHIADVSYFVLPNIALDVEAQIRSTSVYLLQRKIQMLPSLLSEELGSLNPGVDRLSFSMFWELNSMGDVLDRWIGRTVIRSCCKLSYRHAQDFIQGIADVENFSTLEGYSELHGQFEWSDVIRSVKYLHEISKTLKEKRFNGGALQLESAKIVYLFDEDGVPYDSNLSERMDSNFLVEEFMLLANTTAAEIISRAFPDSALLRRHPEPNMRKLKEFEAFCRKHGLALDTSSSGQFHQSLEKLREKLKGDSVLFDILISYASKPMQLASYFCSGNLKDNLNDWGHYGLAVPLYTHFTSPLRRYPDIVVHRTLAAVIEAEELCMKHRRVLKCTDGKVSKQCFTGTYFDKEAAVSPQGKEALSSAALKHGIPSPDLLGSVAAYCNERKLASRHAEDACEKLYMWFLLKRREILLSDARVLGLGPRFMSVYIQKLAIERRIYYDEVEGLTVEWLESTSTLVLSLAGHKRLFKRGGPGNYMALGNAAWVVNPYDLSVETGIDDCDATRMANGEVALSDSEPNSKPWVDPGAFPLTVRMLSTIPVALYAIGGDDGPVEIGVRLYMSSYLK
The following text describes a protein:
Function:
Receptor with a serine/threonine-protein kinase activity required for the specification of the correct number of male archesporial initials and for the subsequent specification of tapetal and middle cell layer identities. In seeds, required for enhancing cell size and the rate of embryonic development.
Miscellaneous:
MISCELLANEOUS: Some ecotypic variation may occur: in cv. Landsberg erecta, meiocytes of a null mutant fail to undergo cytokinesis while in cv. C24, cytokinesis clearly takes place, with the mutant meiocytes degenerating shortly after the tetrad stage; MISCELLANEOUS: In cv. C24, the gene is expressed in the young ovular primordia, but the protein is not present in these organs.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MAFLTALFLFLFFSFSSSAIVDLSSETTSLISFKRSLENPSLLSSWNVSSSASHCDWVGVTCLLGRVNSLSLPSLSLRGQIPKEISSLKNLRELCLAGNQFSGKIPPEIWNLKHLQTLDLSGNSLTGLLPRLLSELPQLLYLDLSDNHFSGSLPPSFFISLPALSSLDVSNNSLSGEIPPEIGKLSNLSNLYMGLNSFSGQIPSEIGNISLLKNFAAPSCFFNGPLPKEISKLKHLAKLDLSYNPLKCSIPKSFGELHNLSILNLVSAELIGLIPPELGNCKSLKSLMLSFNSLSGPLPLELSEIPLLTFSAERNQLSGSLPSWMGKWKVLDSLLLANNRFSGEIPHEIEDCPMLKHLSLASNLLSGSIPRELCGSGSLEAIDLSGNLLSGTIEEVFDGCSSLGELLLTNNQINGSIPEDLWKLPLMALDLDSNNFTGEIPKSLWKSTNLMEFTASYNRLEGYLPAEIGNAASLKRLVLSDNQLTGEIPREIGKLTSLSVLNLNANMFQGKIPVELGDCTSLTTLDLGSNNLQGQIPDKITALAQLQCLVLSYNNLSGSIPSKPSAYFHQIEMPDLSFLQHHGIFDLSYNRLSGPIPEELGECLVLVEISLSNNHLSGEIPASLSRLTNLTILDLSGNALTGSIPKEMGNSLKLQGLNLANNQLNGHIPESFGLLGSLVKLNLTKNKLDGPVPASLGNLKELTHMDLSFNNLSGELSSELSTMEKLVGLYIEQNKFTGEIPSELGNLTQLEYLDVSENLLSGEIPTKICGLPNLEFLNLAKNNLRGEVPSDGVCQDPSKALLSGNKELCGRVVGSDCKIEGTKLRSAWGIAGLMLGFTIIVFVFVFSLRRWAMTKRVKQRDDPERMEESRLKGFVDQNLYFLSGSRSREPLSINIAMFEQPLLKVRLGDIVEATDHFSKKNIIGDGGFGTVYKACLPGEKTVAVKKLSEAKTQGNREFMAEMETLGKVKHPNLVSLLGYCSFSEEKLLVYEYMVNGSLDHWLRNQTGMLEVLDWSKRLKIAVGAARGLAFLHHGFIPHIIHRDIKASNILLDGDFEPKVADFGLARLISACESHVSTVIAGTFGYIPPEYGQSARATTKGDVYSFGVILLELVTGKEPTGPDFKESEGGNLVGWAIQKINQGKAVDVIDPLLVSVALKNSQLRLLQIAMLCLAETPAKRPNMLDVLKALKEI
The following text describes a protein:
Function:
Part of the H2 type VI secretion system (H2-T6SS) specialized secretion system, which delivers several virulence factors in both prokaryotic and eukaryotic cells during infection. May form the spike at the tip of the elongating tube formed by haemolysin co-regulated protein 2a/Hcp2a. In turn, may allow the delivery of the Tle4 antibacterial toxin to target cells where it exerts its toxicity (Probable). Also promotes the release of VgrG2b toxin to the host cell.
Sequence:
MRQRDLKFTFVVGEGKLAFDVVEFELEEALCEPFRLNLKLASDKNAIDFRQVLDQPGTFTLWQDGRPARYVHGIVSHFTQGSSGFRRTRYELLLEPQLARLELCCNWRIFQEKSVPEILQALLKEHRVLDYEQRIYHEHLPREYCVQAGDSDHYLHDRLAFEEGLVYYFRFDEHRHTLVCSDRLYVQERIAGGPVLFSAQPEGDNPQPVLHSFRYSENVRTARQTQRDYSFKRPTYDQEHHLAGEALEHQGSSYERYDYPGRYKRSGAGRPFSESRLRGHRRDARVASVSGDDPRLIPGHAFALEGHPRADFNAWWRPVRVVHRGTQYAGQEEESADAPLGVSYDLRAELVPEDVEWRPAPLPRPRIDGPQIATVVGPAGEEIHCDEWGRVKVQFPWDREGRHDEFSTCWIRVAQNWAGADWGHMAIPRIGQEVIVDYLDGDCDQPIVTGRTYRATNRPPYALPDHKILSTIKSKEYKGSRANELRIDDTTAQISAALMSDHGASALHLGYLTHPRPEGGKPRGEGFELRTDEHGAVRAAKGLLLSTEEQLRAGAGHLDRGVVVQVLEAALKLARELGDYAGEHQGVGHDAAPQQTLQEAVRDLGHGANDESGKSNGGKPAIALSGPAGIAAATPASLTLAAGEHVDSVARQNQQVTAGQKVVINAGSDIGLFAQGGELRQITHQGPMLLQAQKNDIRLEAEQSVEVSASQQHVLVTAKEHITLMCGGAYLTLKGGNIELGMPGNFVVKAAKHSHVGPAHASTSFNAWDSTPFDDRYVLRDEATLEPLPNIAVEVIRGDGGVVKLMTDSQGRLPKQQHLAMDPVQIRILGKGSHNSDTESNT
The following text describes a protein:
Function:
RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U).
Sequence:
MDGVVTDLITVGLKRGSDELLSSGIINGPFTMNSSTPSTANGNDSKKFKRDRPPCSPSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYYTPITPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTVLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGASGIPGNSVLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI
The following text describes a protein:
Function:
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
Miscellaneous:
MISCELLANEOUS: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.
Subcellular Localization:
Mitochondrion.
Sequence:
MFRKIYTNISITLIKQLREASGSPINDCKKALESTDGNFEKAIQYLKERGLAQAEKKMGNQTKQGVIVAYTNNKVAALAEINCETDFVARTSEFLEFSTNFIKTIVNQEQDFSSSNIDSVLNDKRKQLVGKLQENIVIGNLNAFVATKNSVFGVYQHNCLKNTICGLGGSVVELITESELTDVKTQILREGANNLAVTYLGLKPRFLYQHEVSSDVVDQIRKEVEKEFGSKTAQQQNFIVKGKLQNYYSDNVFEHQEYFLNEDEPKTIKQYMAKELEEVIKDKVKIGRCLYLTI
The following text describes a protein:
Function:
VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MLIRAFITLAFLFAQKVAETSADANKPCSTACGCKKRLHARLGLYTTKLKEAKQTNHQNLKEYNSLLLAAAVGSPLDTTIILPILAGSGELIQQCNEQISAADKAVAAATIKVGEASGVYNVIHKLKDGMGKLMINFGGGDLQLPASKFTSRTLGGINANACCSSNNGEEGVKTDLEHEPKEPEPTKLITHAYLEAKCDSNPGAPATCHNAAVDQDTQISIGLGFGNGAKDEKSAWGAGSHTKMHKIASTAVDFFSSNETAAHQALKALATDKTGLPACHSLQDFGAMAETRAFQLMLLKLAAGKPEAEKVGPDDRQDIDSAITSSYGKSGANYKDKIWDQIQKTEVPQGKQTGEKTAALEKGADIKLQTEALARLFAKEIKEKKQAKTTQKVSKTTDCNKQTEKTAEECKNLGCDHDAENKKCKPKAGTENTAPGAGATAGCTKHGTDKPKCEGDKSCKGNGKECKDSSFIVNKKLASMNAAFVSFIAF
The following text describes a protein:
Function:
Transcriptional activator that binds to the SBP-box DNA core binding motif 5'-GTAC-3'. Can target the TCP motif 5'-TGGGCC/T-3' through interaction with PCF1 and PCF2. Key regulator of the plant architecture that controls shoot branching and panicle development. Promotes panicle branching. Promotes high grain yield. Binds to the promoters of TB1 and DEP1. Suppresses rice tillering mainly through positive regulation of TB1. Regulates plant height and panicle length through positive regulation of DEP1. Repressed by D53 in strigolactone (SL) signaling. Acts with D53 to mediate the SL-regulated tiller development. Functions as a direct downstream component of D53 in regulating tiller number and SL-induced gene expression. Binds directly to the D53 promoter and plays a critical role in the negative feedback regulation of SL-induced D53 expression. Involved in defense response against pathogens. Phosphorylated at Ser-163 in response to infection by the fungal pathogen Magnaporthe oryzae. Phosphorylation reduces SPL14/IPA1 binding to the GTAC site in the DEP1 promoter and enhances binding to the TGGGCC site in the WRKY45 promoter. Binding to the promoter of the pathogen defense gene WRKY45 activates its expression, leading to enhanced disease resistance. Reduces gibberellin-mediated disease susceptibility by stabilizing SLR1. Possesses transactivation activity in yeast cells.
Miscellaneous:
MISCELLANEOUS: Plants overexpressing SPL14/IPA1 exhibit enhanced disease resistance against the bacterial pathogen Xanthomonas oryzae pv oryzae (Xoo), and increased grain yield.
Subcellular Localization:
Nucleus.
Domain:
The SBP-type zinc finger is required for the binding to DNA.
Sequence:
MEMASGGGAAAAAGGGVGGSGGGGGGGDEHRQLHGLKFGKKIYFEDAAAAAGGGGTGSGSGSASAAPPSSSSKAAGGGRGGGGKNKGKGVAAAAPPPPPPPPRCQVEGCGADLSGIKNYYCRHKVCFMHSKAPRVVVAGLEQRFCQQCSRFHLLPEFDQGKRSCRRRLAGHNERRRRPQTPLASRYGRLAASVGEHRRFRSFTLDFSYPRVPSSVRNAWPAIQPGDRISGGIQWHRNVAPHGHSSAVAGYGANTYSGQGSSSSGPPVFAGPNLPPGGCLAGVGAATDSSCALSLLSTQPWDTTTHSAAASHNQAAAMSTTTSFDGNPVAPSAMAGSYMAPSPWTGSRGHEGGGRSVAHQLPHEVSLDEVHPGPSHHAHFSGELELALQGNGPAPAPRIDPGSGSTFDQTSNTMDWSL
The following text describes a protein:
Function:
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
Miscellaneous:
MISCELLANEOUS: Present with 846 molecules/cell in log phase SD medium.
Sequence:
MSDLQKLQRFSTCDISDGLLNVYNIPTGGYFPNLTAISPPQNSSIVGTAYTVLFAPIDDPRPAVNYIDSVPPNSILVLALEPHLQSQFHPFIKITQAMYGGLMSTRAQYLKSNGTVVFGRIRDVDEHRTLNHPVFAYGVGSCAPKAVVKAVGTNVQLKILTSDGVTQTICPGDYIAGDNNGIVRIPVQETDISKLVTYIEKSIEVDLLVSEDIKNGIPAKQAQNDRRSVLKKYI
The following text describes a protein:
Function:
Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4. In kidney podocytes, plays a role in podosomes and filopodia formation through CDC42 activation.
Sequence:
MLEKCKYNLVDDSMDQRIPADNEGQFQHGLTFEVKFIGSLDIVRPKSRIEILAAMRRIRYEFKIKNIKKKKVSLIVSVDGVKVVLRKKKKVKFEYSWDESPVTLAQDPIFRIFYVSHDSQDLKIFSYIARDKKSNVFRCNVFKSKRKSQAMRIVRTVGQAFEVCHKQSLDNADAWLVKGEEERSKDEAVAAGSSTERAGDADPETDEKVEEESKSPLSSPLSVSHQVQLLQRQFQQQEQRSHAASAQVVLLQQQLSVETNARTEAQARVQQLLQQNTELLQHLSLLVKHVQELELRTQPHKNSPLGSQDSLLEIALRANMPAVSREPKPNPLLSAQRSFPLSNSLVRLDGFHFFTGASEQEKKPEQDRDSGRGQDEDQSGGSSPPENQFLSALDTPGFRESGIASGYESNTDESDDRDSWGQ
The following text describes a protein:
Function:
GTPase-activating protein.
Domain:
The PH-like region is similar to the PH domain but is not detected by Pfam and PROSITE prediction tools. It is unclear whether it is a real PH domain.
Sequence:
MENINIEYGIDSNLNLDKFQDNEMEIKNLSKSFDNNNNNNSNTNNIKNNNRERSRRKSLSMPLLEPLPKPKRPPVPPRAFLMNDGADEKITNYIPTTPPSINITFEKKEDGDNYDDNYDDNYSGEDIKTSTTPPQFNSPEFNKNKPLPPIPIDQEKEDYHTMAPKPLPRVPSKIETFNDQNNNEGLQNSTSPLSSSPPPLGNLLNTSNGWRSANKPIDSSFSNIAPKRSTTLFDVTNPTIFPSSLNSSGSCCSSSGSGGKSPSNFLNFEPSKPNFENFDDYVFGNDSSELSQSQISPVVRTRRQRVFTRKAATMKLLDNGVDTDDENESELSKKSGTTLDSEPNLKSVSSSNRGSFVISKSSYNLRGSCSDEDDQENQTTNKNNSNNNNNNTTTNNNNNNNNNNNNNKDTLKVTETKHGRTVSLPEEPVSTLIPNATVSKKRPSLFNKFDFKSVIFEKIEEQQQKFESIPSRRSQLPYINDSTIFNKVVKEIIETEADYLDHMEITINFYLFAALEMVKYKILEKRDIFSIFSNFEEVYHISLKIYPMLLNCIPLLEKNQYPNIEEVFLFNSKSFQRYGSYLSSHDSCNKFLQEILLTNQTAAQIFQKLIPICKLNNLHSFLIKPCQRLCKYPLLLKELSKALPKEDEQNHKTIKRTTSLMGKIVSDINGKMKNDTKIQEIIKEIGTKDIEYLLHHQTFIGEGKVKKVNKNGSTSEGTLYLFNQRIVFAEKNSLFNKKATVISLSNISRVCDYDYRYPSGFAIYHNSKKVSTSSSSNLGTLSLGALIIISDEKLKWMNKIEDQIVSERVLAGTYTYVTNHFESFKNLENCSFSQSDSQSDFVDHDIQQEQQEQQQQQQEEEQTRVKIPQIVEPLSQQHDQPKLDHQQSSIQPKLSFPHLKQPKQDEKPIKKPKSPKHKNTEPENFSFY
The following text describes a protein:
Function:
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
Subcellular Localization:
Nucleus.
Sequence:
MPRENDEENSPQDGMYISAPDEYQMYQSEQQIYSAFSMDESQDKYANINNEIQDEPHLQDNIDDEDMFIKTFKPGPNGYQEIPLELVQNFFDITELEDQACTSTGRTKFKVVINGQEMIIDGTVTPANEYTPQQQQTPGELEEELEEPVEYNMMHLPEAVMSGGQSMQMITLPDGQLALQVTQMEQKPQMAQVVTVDEEGNIISTDGTFAIGMPSSAQSQGAVMMTMQTDEFGNMYLQEESAPSTSGVGNFHCMEVTGDPAEIAAMYPGMQMLAVNPDGTLESVFEDGLPPPTAATTYVNAKQYHRIMKRREARARLESSGRVPKIRSKYLHESRHRHACNRVRGEGGKFNSKKGRDANDITGDDHSPIKMKKFEMNSPTQNDKEDIFTADKNDVVPLLPRPIFTRPAKNAPALKARIPTPLTVRSTTTPNQRPTAVITHLPLPPQSKVRPPGFRVARPSEIKKLLPTTYSKPGSATSKVDSLPDKILEESPSNSNSPPYSAEIDDSLKKEPDFSNLNSL
The following text describes a protein:
Function:
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
Subcellular Localization:
Nucleus.
Sequence:
MEGGRVSALRVHRLARSAAAKRKKRALAGRRRRMAAALLLLAAKQRRRRRKKAAPPASPPPPPPPPPPPPPPPPPPPPEETPVQRVLRELGGIPHSKRRAARLFDWLIAPLPAAAFFERAWEREPVVVRRAQPAYYGGLFSAAELDALLRAEDLRFGRHLDAARLDGGGRRRSPHPEGARATPAAAWGLYRAGCSLRLLCPQAFSAVVWHVLALLQEHLGCLAGCNAYLTPPGAQGFAPHSDDVEAFVVQLEGRKRWRLYRPAEELPRRPGPDLAPGALGRPLLQVVLRPGDLLYFPRGFVHQADCPAATGQHSLHLTLSAFQRNSWGDLLEPLLPAALEAALEEDADFRRGLPRDYLDYMGARHADAAGDPRRAAFLARLRRLLARLARYAPVDAVADQRGKAFLHDCLPPVPTEAERAGGARALAAPRWEAGGVRGAAPRLRPATRVRLLQLGVARLVGEGGGAVLYHTLDNGRFYHQSAGGPAGREGPEEEAPRGLEVPPHLVDAVERLFRAYPAFVRLGSLPCDRPADLLALAQDLFHRGLLVTRGPLGLDAGGGADGGAPPRRRRRPGPPSPPERVGGGGAPRPPTRPTKRGASVRVRERRPGGGTRRGEASEEGETGGGGRPAGGSGAPSPSCGGGRNRGPEGRGGVGPGSNPGPPPCSDRSPGPAGARLGALSSTRLPAPLGTAPSPSASPDPDGPRRAGRPASRAPPEALPTFPTDPRLPSLGPAAPSRRRGGRGRSRGRRPRASWPLLPLGDGIRIGRWPGPRTCILRPRFAPPTAPRRLSWLSGKSPGWGVRGRGFESRLRRLAV
The following text describes a protein:
Function:
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
Subcellular Localization:
Cytoplasm. Mitochondrion intermembrane space.
Domain:
The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation; The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters; The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.
Sequence:
MPAPVPPTAFAQPSGPATQLVLGSMQRAPEYQALLTSLKSAAPPSSSVQGEMVDRILDNATTLPPPPLTIHLVLPLPLPSNLLSAIPPSTQIFIHIPADSESQLGALHSALASHSFTPVLPTPSPSTLAYTSPSAPSLPAVASEPSPAPSSSTPVTLSGARPLQLRRNGDKARKAALWAIDSPLIPDGGKSLLTPADRTRPDCVFPAENGKPVKRRRACKDCTCGLKELEQEEEAQTSAAVQEAQKAFFLEGDDDIPENLKKATEGMEGIWPADKRAEAKKTSSCGSCYLGDAFRCSSCPYLGLPPFKPGEQVQVSIGDDI
The following text describes a protein:
Function:
Probable ATP-dependent RNA helicase which may be involved in mRNA splicing.
Subcellular Localization:
Cytoplasm. Nucleus.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MDPPKLTFISKRDTKKKDEVNKEQPTKNLKILDLFSNDEEFSNPTQEEPTNTLQEKLMNVDPLEFFSKGGLKEEQKKERDDHRDDYRDSRDRDRDYRDNGGRDRDRDYRDGGGGGGGRDRDRNRDRDRDRDRDYRDGGGGRDRYRDNDRYRDTDRYRDNDRRDGSGSGSSRRRDERRENSGRRDYRDNDRRDDRRDNGRYGRDNDNSGGGGSGKNSSDKKEEINPVSNNNDIHKDRIKRDTTQFSHKVFEQINNKRDREDPELRDIKVDYMGIKRDENRKKIKGEKGKFVFEWDSSEDTSSDYNTLYTKKLEIQPQFGHGNFGGYEKNNNNNGNHYNGNIYNNNNNNNNNNNNNNNINNNNNGSMIGGKQISELPDTHWSKKPLKSMTKRDWHIFKEDFNISTKGGIAPNPIRTWQESNLPREILEAIRQLGYEKPSPIQMQSIPISLTGRDILGIAETGSGKTCAFVIPMLIYISKQPRLTKDTEADGPYALVMAPTRELVQQIEKETRNFAQHFGFRVVSLVGGQSIEDQAYQVSKGCEIIIATPGRLNDCLEKRYLVLNQCNYIVLDEADMMIDLGFEPQVTSVLDAMPSSFLKSEDDEMAEKQESDRSHIYRTTILFSATMPPLVEKLSKKYLRRPCTITIGEAGKVVDRIRQTVIFVKSENDKKEHLTQLIKDGPPPPIIIFVNKKKHCDIIAPVLEECRVSYTILHSGRSQEQREAALEGFKKRKYEVLIATGVASRGIHVDGVTHVINFDIPKNIEDYTHRIGRTGRAGSAGLASSFITDKDVEIMYDLKQILTSTNNIVPIELLKHPSSQQKHGSSKDHNKSVIFK
The following text describes a protein:
Function:
Potential transporter for phosphate.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MRELAVEILVVLALITSAFFAWSMGHHYAGAVVGPAVGGGAITIKKGLLVAGALVLIGSLVSPVVKTYVQLTNLRPAGHYSALLSAAATTTLATYAKIPTSTIQLYTASLIGAALTVGAAVNLQLLAVLVAAWAAAPLTAYALAPLVSKLTPSNTKLLLRISMFLSALVLGLNDVSNAATSLVGVVIDFITAKGLADFFMSIGLLTWGHRLVETIGGELGNLSPRSYLAAHVTKIATLAIFNSLGLNASMNQTLIGAMAKLGAERRALKRIFIGWLTSPLLGAAFSALVTFAMATWRLG
The following text describes a protein:
Function:
Transcription factor which regulates the expression of genes for gluconeogenesis, the TCA cycle, and glucose metabolism. Involved in the cell wall remodeling process and drug resistance.
Miscellaneous:
MISCELLANEOUS: Present with 799 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSANSGVKRASKAFKTCLFCKRSHVVCDKQRPCSRCVKRDIAHLCREDDIAVPNEMPSQHESSPNDNNIQGKYANKAHTGIPSDYQNEPVNKSGSTYGEELSPKLDSSLVNDTTSLLLPQQPVFVSENVGSEFSSLNEFLSMLENPLLTQTSLSSSSASNVHLENGSQTTQSPLEYQNDNRRDEIGVARQENRSPTIMSGSSNSISKGDKQDQEKEESRILANANENSAPTPKEQFFLTAADPSTEMTPEHRLKLVINAKLEAGLLKPYNYAKGYARLQDYMDKYMNQSSKQRILKPLSTIRPAFRTIARSLKDVDLVLVEESFERMLLSYDRVFTSMSMPACLCRRTGEIYRANKEFASLVDCTVDDLRDGKLAIYELMTEESAVNFWEKYGSIAFDKGQKAVLTSCSLRTKDGIRKRPCCFSFTIRRDRYNIPICIVGNFIPLS
The following text describes a protein:
Function:
AMP deaminase plays a critical role in energy metabolism. Catalyzes the deamination of AMP to IMP and plays an important role in the purine nucleotide cycle.
Sequence:
MNFNRMDTAHRLRVDVRLYGGSMGNQLNDKGTASSTPTISSDDLSDLADSPVDEKAEADVEVTNEISAPYEVPQFPIEQIEKKLQIQRHLNEKQATGPRPVATAAVLATNRESSSSTEGRESAVTMERNDADINFQRVSISGEDTSGVPLEDLERASTLLIEALRLRSHYMAMSDQSFPSTTARFLKTVKLKDRINNLPVKEVSDIIRKMSVANIQESADVHLRHSPMKITNPWNVEFPNDEDFKIKPLNGVFHIYENDDESSEIKYEYPDMSQFVNDMQVMCNMIADGPLKSFCYRRLCYLSSKYQMHVLLNELRELAAQKAVPHRDFYNTRKVDTHIHAASCMNQKHLLRFIKKTLKNNANEVVTVTNGQQMTLAQVFQSMNLTTYDLTVDMLDVHADRNTFHRFDKFNSKYNPIGESRLREVFLKTDNYLNGKYFAQIIKEVAFDLEESKYQNAELRLSIYGKSPDEWYKLAKWAIDNDVYSSNIRWLIQIPRLFDIFKSNKMMKSFQEILNNIFLPLFEATARPSKHPELHRFLQYVIGFDSVDDESKPENPLFDNDVPRPEEWTYEENPPYAYYIYYMYANMTVLNKFRQSRNMNTFVLRPHCGEAGPVQHLVCGFLMAENISHGLLLRKVPVLQYLYYLTQIGIAMSPLSNNSLFLNYHRNPLPEYLARGLIISLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSSCDMCELARNSVMMSGFPHAIKQQWLGPIYYEDGIMGNDITRTNVPEIRVAYRYETLLDELSNIFKVNQTCSIADMNAT
The following text describes a protein:
Function:
Antibacterial activity against several Gram-positive and Gram-negative bacteria. Antifungal activity against A.fumigatus, B.cinerea, F.culmorum, F.oxysporum, N.crassa, C.albicans, C.neoformans and S.cerevisiae.
Subcellular Localization:
Secreted.
Sequence:
MNFSKIFIFVVLAVLLLCSQTEAGRLKKLGKKIEGAGKRVFKAAEKALPVVAGVKALG