lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Ligand for members of the frizzled family of seven transmembrane receptors.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MNLVTVFMVCLMAISAWAEVESKSKPGRGRGSMWWGIAKAGEPNNISPLAPGMAYLDPAIHATLRRKQRRLARENPGVLAAIAKGANLAINECQHQFRTRRWNCSTRNFLRGKNLFGKIVERGCRETAFIYAITSAAVTHSVARACSEGSIESCTCDYSHHNREPQMNNMGVVAGVGDWEWGGCSDNIGFGFKFSRDFVDTGERGRTLREKMNLHNNEAGRAHVQAEMRQECKCHGMSGSCTMKTCWMRLNSFRTIGDILKDRFDGASRVMVSNSLRSTSVNENTLTNRAGSANLKTNANSVGGSASPNSVLSNSIHARGHQQKRVNRYNFQLKPYNPEHKPPGSKDLVYLEPSPGFCERNPRLGIQGTHGRQCNDTSIGVDGCDLMCCGRGYRTQEVTVVERCSCTFHWCCEVKCKLCRAKKIIHTCL
The following text describes a protein:
Function:
Acts as a mechanosensitive calcium channel in response to membrane stretch (By similarity). Regulates intracellular calcium levels and cell volume for survival in response to hypo-osmotic shock (By similarity). Involved in maintaining vacuole integrity and protecting the nuclear envelope upon hypo-osmotic shock (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Domain:
EF-hand domain is involved in the detection of calcium concentration.
Sequence:
MTTPVNEVPEPSYPAAERRRRSDSDSSPTVDGNAYVHDESQPHDGAYAGAQYGSHLQVDTTFQDFDKTSRSPSAAREQAMRLEDDLAVLEAERVASRSTHGTEKDARSGDVHSLTRSRSRRAEDVDEFDEATNPLHEKAAVYNPPENPSTGVSKFIKRVHESSFIVRYFTYIVPLVLILLIPLLVGALAYPDASVGGVELLWFSVWLEIVWLTLWAGRIVAKLLPTPVNIFASIFTNNSKKWRDVAKQLELPVTLFLWWLGVEISFLPTMKNHHVDGNSRTRDWENTLNKIIISVFVWTILNLIEKFLLQLIAMSFHRRTYSDRIEINKFQIGSLTKLYAFSRNKIAETDEAFEEKQDKSGSGAKTPLRYAGKARGLALGALNKVGDVAGAVAADFTGRKANSSSHPSQVVIALLRTTAGCQTLARRLYRTFVREGFDTVFPGDLKEAFDDNEEAEAAFSMFDKDMNGDISMEELEAVCVEIGRERKAITASLKDLDSVVSRLGNVFEFFVAVIAIIVFLTLISTSAAGVLTSAGSSILALSWLFSATAQEFLQSVVFVFVKHPFDVGDRVTIYGNSGEAGLGDDYYVKQISLLYTEFKKMQGHIVQAPNSYLNTLFVLNQRRSGALAEAVPVVIKYGTTLEQMDALRQRLLEFVRSERREFQTNILTELRAVTENFSVTLNVVFFYKSNWQNEGLRLQRRNKFICMLMVALQEIGIEGPRMNLQGASVDIPYHIAGFPPPYQARDGPPVNDDGGQHPPHTPSSGDDQHHQPGHSPSYRRPSILRKGMVAANARARGVSISSRKHVDFSLGMRDVASNDIMGDVFEARSPAADSAVRQVIAERRIQEEEAERQSVESSRQRNSGSRTNLTVPTSTNEARHSIDSQGASSLSSISRNRFFRHRSHSHSTRQEDLMEQGRSSEQGSSSAAAIRPISPSYHPDEKKL
The following text describes a protein:
Function:
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
Sequence:
MKLFGSSGIRGIVNKEVTPELALQVGLVLGSRKKTAVIGRDPRVSAPMIEHALVAGLTAAGCDVTKVGMVTTPTLAYAAREYECGVMVTASHNPSEYVGIKLWNPDGMAFDSAQQEEIEDAIENENFLRVTWDLIGKVAENGNAIRDHMDLIEGLVRDSKLRVVLDCGCGAGSTITPYLLQELGCQVITLNSQPDGHFPARNPEPNDQNLSLLKKAVVAFEADFGIAHDGDADRMMAVDEKGNFVSGDELLAIFGRFECGDEKGTVVVPVDTSMMVDDYLEGSEIIRTRVGDVYVAEGIKQYGAIYGGEPSGSWIFPKISYCPDGIYAAAKLVEIVREKKLSELRAELPVYATKRGAFPCANEKKAELMEKVKTKLEPLGKVLDIDGIRVELENGWVLVRPSGTEAKVRITAEAREKVDEIYEMAEKIVKEALK
The following text describes a protein:
Function:
DNA annealing helicase and endonuclease required to maintain genome stability at stalled or collapsed replication forks by facilitating fork restart and limiting inappropriate recombination that could occur during template switching events. Recruited to the sites of stalled DNA replication by polyubiquitinated PCNA and acts as a structure-specific endonuclease that cleaves the replication fork D-loop intermediate, generating an accessible 3'-OH group in the template of the leading strand, which is amenable to extension by DNA polymerase. In addition to endonuclease activity, also catalyzes the fork regression via annealing helicase activity in order to prevent disintegration of the replication fork and the formation of double-strand breaks.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MPTAGEKRKAPTPWTSYLTNEASAQLDFLPDKLRAKLLPFQKDGIVFALRRGGRCMVADEMGLGKTIQAIAISYFYKEEWPLLIVVPSSLRYPWIEELEKWIPELEPEEINVITNKTDTGRIATSRVTVLGYGLLTTDAETLLEALDRQNFRVVIVDESHYMKSRTAARSKILLPMVQKAQRAILLTGTPALGRPEELFMQIEALFPQRFGTWVEYAKRYCNAHIRYFGKRRQWDCRGASNLSELHQLLNDIMIRRLKSEVLSQLPPKVRQRIPFDLAPATVKELNASFEEWQKLMRAPDAGAMETVMGLITRMFKQTAIAKAGAVKDYIKMLLQNDSLKFLVFAHHLSMLQACTEAVIESKARYIRIDGSVPSSERIHLVNQFQKDPDTRVAILSIQAAGQGLTFTAASHVVFAELFWDPGHIKQAEDRAHRIGQCSSVNIHYLIANGTLDSLMWAMLNRKAQVTGSTLNGRKEKLQATEDDKEKWGFLQFAEAWTPSDSFEELKDPVFTHFEKEKQHDIRSFFLPKPRKRPLETSGDAAEAVKEKTTVASDPRNMATKEGTTDKNGVEPETKRLKSLSTRDHCSALEEKPSLQAKATSIDGVHEVKSPLASPALSEKRWQCGFCTFLNDPGLPYCEMCESPQGRAAGLNHRQDNNKEEKEESQKSTSKNDQARLHCVKPCSEQPEVERLARNKEETSKGEGKTDCHFRQGMESQ
The following text describes a protein:
Function:
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.
Sequence:
MSRSDSQEKLSESDEQYVKLTHREHVLTRPDSYIGSIEPRECKMWVCNEDGKFEFREISYVPGLYKIFDEILVNAADNKQRDPPLTTIKVEVDPAQNRISVWNDGKGISTQKQFSPNDNCEYYIPEFIFSQLLTSSNYNDKQEKVTGGRNGYGAKLANIFSKKFHINIYNADEGINYQQTITDNMTNIQPPKLKNGKGKGSYTEISFWPDLERFNLQTITKDHVDLIRRRVYDLAGILPKVKIFWNGNQVPIKKWEDYCKVYLKEDVKPLVCEVKNEKGYTWKIGVAPSKSREFQQISFVNCVATSNGGTHVDVVVNQITKYITDYLKNRRSGKVETKPSVVKNFLYVFVDSLVINPSFDSQTKERLTLDQKKLKDDCKLPDNFLDKILKTDIVALVTEYANFKEQRKVANMKGTKKGRLIINKLEDANMAGKAESLKCTLILTEGDSAKATAVTGLATIGRDYYGVFPLRGKLLNTRDISAKKLSENDEIQNIIKIMGLDPMEKYENDDSMKRLRYGSIMIMADQDVDGSHIKGLIINFVHSMWPNLLKKRNFITEFITPIVKVTKGNNKKGAISFFTIPEFSQWKAANNNGKGYKMKYYKGLATSTAEEAKEYFSNISKHKKVFIYTNENDEERINLAFAKKRADDRKNWLAQLDANETYLGTKDTHIKYSDFVDKELILFSSYANYRAIPSSIDGWKPGQRKILWVCLKNNIKNDLKVAQLSGKVSEQAAYHHGEASLNETIIGMCQDFVGSNNINVFQPIGMLGTRLAGGEDSGSPRYVYTALEKITRTIFMKEDDDLLTYNTDEGLPIEPVTYIPIIPMVLVNGAKGIGVGWSSEVPQYCPQDIIDNLRRKMNDEPMVEMTPWYSGFTGKIIPIQVIKDGVKQPIVKWESRGIVKKIDDTTIEITELPIGIWTYDYKKFLEGLTVGESLNPHKKLADRKAAAAKAKRTKKKAAAGDDPVEQADVEEKVNLGGPKISEFREYHTNVSVHFIITVDDSQMREIESVGLREFFKLKSSITATNMTLFNAQNKIVQFNSPLDIINDYYPVRMKYYEERHRYLIDALQLQYKKLSNQARFIREVIAGIIKVNGVPRATILAALERGNYDLYDDKELTKRIKFADEVIQQHNEEEEEQNEFKSESNADHLALLEKGYDYLLAMKIWTLTKEKADKLDDEAKKKNQELEEMLKKKPIDFYKEDLDKFEVEWKAFEAKREKTRLENVADAEKVNRKSIAKNKKAADQKKAKQQKKDAKAKQEAAALQTANGEELKQEVENQMPTKEETVVQESDDDIIVINEDVKKPKKERKPKAETTTPTKEGEEKPKKERKPRVKKEKKEGEEETEEKKPAATKVKKETTETETKKKSKTTKKSNKSAFEDEDEDDDVDVDLEDSDEEPVETIASRLASRRKTEPKKQAILEEFFSGKKKDGEDGEEEEDEDDDQDEDDDGDDAWEDDE
The following text describes a protein:
Function:
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
Sequence:
MTDLSDIRREYTQGGLRRADLPKNPMQLFELWMTQARDAQLSDPTAMCVATVDEHGQPFQRIVLLKRFDDSGFVFFTNLGSRKALQIAANNKVSLHFPWHPIERQVSILGEAQPLSTAEVLKYFMTRPKESQIAAWVSQQSSKLSARQVLEGKFFEMKAKFAKGDVPLPSFWGGYLVKPSSIEFWQGGEHRLHDRFLYTREAQAWQIDRLAP
The following text describes a protein:
Function:
Probable thiol-disulfide oxidoreductase that may participate in various redox reactions.
Subcellular Localization:
Plastid, chloroplast stroma.
Sequence:
MDSIVSSSTILMRSYLTPPVRSCSPATSVSVKPLSSVQVTSVAANRHLLSLSSGARRTRKSSSSVIRCGGIKEIGESEFSSTVLESAQPVLVEFVATWCGPCKLIYPAMEALSQEYGDKLTIVKIDHDANPKLIAEFKVYGLPHFILFKDGKEVPGSRREGAITKAKLKEYIDGLLNSISVA
The following text describes a protein:
Function:
Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.
Subcellular Localization:
Nucleus. Chromosome, centromere, kinetochore.
Sequence:
MTLRDHHFYNVTYTAYRLSPLFGFEYSNLTEIGKKLTRFLRYGTDRTGYFTNSTRFADLIIEKATFTEFGNTSSFPKFLKLDISYETSSDLEVKRKGQMFFFESFRKFSHAEADRTRLSLEGNSVFFSLALVRMDGALWMAVEQFLQQEFDTQILPCLIAPEILLEFLKIWQNHVNSQTALPLELTWTTGNPNLSSVTISIRPEDLKKIFRSSSFFYPILMEHIKRCTSLDLTNSVFSLSKVNTDCAILTSSGKLKIFSKAQNIVFDVLLALEPMQLPEY
The following text describes a protein:
Function:
Exopeptidase which selectively removes arginine and/or lysine residues from the N-terminus of several peptide substrates including Arg(0)-Leu-enkephalin, Arg(0)-Met-enkephalin and Arg(-1)-Lys(0)-somatostatin-14. Can hydrolyze leukotriene A4 (LTA-4) into leukotriene B4 (LTB-4).
Subcellular Localization:
Secreted.
Sequence:
MAAGEPKAGGRALRAAQVDDVASASNFRAFELLHLHLDLRAEFGPPGPGPGSRGLSGSAVLDLRCRAPGGATELRLDSHPCVDVTAAALRRGRPEPGRPEPEPEPLPVCTQPFSHYGQALCLRFSQPCAAGECLQVRITYRVGEGPGVCWLAPEQTAGRKKPFVYTQGQAVLNRAFFPCFDTPAVKCRYSALLEVPDGFTAVMSADAWEERGPNKFFFRMSQPIPSYLIALAIGDLVSAEVGPRSRVWAEPCLIDAAKEEYDGVIEEFLATGEKLFGPYVWGRYDVLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEIAHSWFGNLVTNANWGEFWLNEGFTMYAQRRISSVLFGPAYTCLEAATGRALLRQHMDVTGEDHPLNKLRVRIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQGQFDDFLKAYVDEFKFQSILADDFLDFFLDSFPELKKQRVDSIPAGLEFDRWLDTPGWPPYLPDLSPGDSLMRPAEELAQLWAAEELDPRAINAMPTSAWKTYQLVYFLDKILQKSPLPPGNVKKLGETYPKISNAQNAELRLRWGQIVLKNDHQEDFWKVKEFLHSQGKQKYTLPLYHAMMAGSKAAQTLAKETFAATAPQLHSNVVHYVQQIVEPLGR
The following text describes a protein:
Function:
Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type IV membrane protein.
Sequence:
MAVANGWPDEKSTDQWDNLRKQARKLESELDDKLVAYRKIASGPEDSKDGTEACIKDLLKSLQHVNTQMQAWVSNGGSHVLSHTLARHKDILHELTQEFARINTRAKANLEHAKLLETFGRSNKKKDPENGQNGDSSEQALLRESANISRTSGQLDSVIGQVRATLSDLNIQRSVFGDANSKLGLIQSSLPTVNSILASIRRKKSLDNIILAIVTFAKRRNPTIHAHVATSTGPKSPRSPECHWKNSLCS
The following text describes a protein:
Function:
RNA-binding protein that initiates the antiviral response and is required to restrict the replication of RNA viruses. Acts as a double-stranded RNA (dsRNA) sensor that recognizes viral RNA and then interacts with MAVS to initiate the type I interferon response. Also required for immunity against some bacteria, such as mycobacteria.
Subcellular Localization:
Cytoplasm, Stress granule. Mitochondrion outer membrane.
Sequence:
MDGRPLGMDVPPRQPNQRGHVVGGIPQRGRNWAHNPPARAPRGADQPRRDPRANNNLLPRWQREERFGGMGRNPQQGRRNQGGQANDEARGQRNYQEYEARRRNENRDGRERRPPPAEHLHFQQDPPQHWGPRPEAGEPPHQVRRIGYKFLEGLLQKDPSEVVITLASSMGLKELLSQASMKPTFLTLLLQVFRKACSSKMDRQSILHLLGLLKNSNFLKVCLPQYVASMITEPCPAVRHQYPEHIGNIISLLQDLVSVYPASSVQETSMLISILPASLNALRASGVDIEEEAEKNLEKIQTILEHLQERKREGTLKVDTYTLVHPQGDDQEVNYRTMTIYPSYNEVHLDEKPFLRPNIIVGRYESTSIYLDTHFRLLREDFVRPLREGILELLQSFEDQGLRKRKFDDIRIYFDTRIITPLCSSSGIVYKVQFDTKPLKFVRWQNSKRLLYGSLVCMSKDNFETFLFATVSNRDPEDLCNGIVQLCFNEQSQPLLADIQPSDSFLMVETTAYFEAYRHVLEGLQEIQEEDVPFQKNIVECRTHLREPQYLLMGGKYDLTPLLGNPPTDGESSRFAEEATRPRINILDPAQWPSREALKLDESQMEALQFALTRELAIIQGPPGTGKTYVGLKIVQALLTNEHVWQISVQKFPILVVCYTNHALDQFLEGIYKCQKSSIVRVGGRSSSEVLKQFTLRELRNKREFRRNLPMHLRRAYMNIMTQMKQSEQELRKGSQHLECTTNGVLHERHLEKYIAPHHWNSLMNGPDIEWFYYRGFKQSMILEWLGLGFTTFTQSAAPSSPAGAENAAQPEKEEEEDGEEEEGLIEIPEEADLIQADRVIEDEEETIRPRRRRKEEDGAVQELAKALLAIRLDNLGTGAAEPSGQVAGEWETQRTQKKKMKRKVKLELRKLNTMTEAEAKEIQDLWQLDLNSRWRLYRLWLQMYQSDIRRKVLNHEQQYQASAERMAELRLQEDLYILKDAQVVGMTTTGAAKYRQILQKVEPRIVIVEEAAEVLESHTITTLSKACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFERLVKVNIPFVRLNYQHRMRPEIAQLLTPHIYQDLENHPSVLKYEQIKGVSSNLFFVEHEFPEQEIQEGKSHQNQHEAQFVVELCKYFLCQEYLPSQITILTTYTGQLFCLRKLMPAKTFAGVKVHVVDKYQGEENDIILLSLVRSNRAGKVGFLQISNRICVALSRAKKGMYCIGNAGMLARVPLWSRILHTLRENGQIGRALTLCCQNHPDTRTRVARASDFQRVPEGGCDLLCEFRLGCGHVCTRACHPYDPSHAEFRCMKPCQKVLCAAGHRCQLVCFQPCGDCQVKVPKTLPGCGHRQPVPCSVAEEDFACQAPCRRLLGCGHRCRGACGQECDPLCAELVPVSLPCGHSQEVKCGRAADPRRDGAVECAADCAATLDCGHPCPGSCHGCSEGRFHERCGQPCRRLLICSHQCQEPCTGACPPCRVTCQNRCVHSRCRKTCGELCSLCVEPCTWRCQHYQCSRLCSEPCDRPPCDRPCARLLACGHPCIGLCGEPCPAGCRVCQPDEVAQIFFGSEDEPDARFVQLEDCSHFFEVRALDRYMNEPGDEEVAIRLKVCPVCQVPIRKNLRYGASIKKCLEEIERVKEKILGPAGEIAAGRERLRALLREKDVLRRTFPAEYLKLEEKLERPDLSAKALGLAENLIGFFERLAELCQGLDRLDVREREGVRRRLAQVQEWLDRERLSFSGQELADLQGEVQRLTYLVGFLARCKTAGGQLSGAPAREAAAVRLILESTRRFGRDDERLVREKLKVLEEALPRSGLGVSEKERVEIVTAIGCPRGHWFKCPNDHIYVIGDCGGAMERGTCPECRAVIGGERHTLEATNRLASEMDGAQHPAWSEAANNLFNFEEFQRPR
The following text describes a protein:
Function:
Transporter for bile acids.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDGLDNTTRLLAPSSLLPDNLTLSPNASSTSASTLSPLPVTSSPSPGLSLAPTPSIGFSPDLTPTPEPTSSSLAGGVAGQDSSTFPRPWIPHEPPFWDTPLNHGLNVFVGAALCITMLGLGCTVDVNHFGAHVRRPVGALLAALCQFGFLPLLAFLLALAFKLDEVAAVAVLLCGCCPGGNLSNLMSLLVDGDMNLSIIMTISSTLLALVLMPLCLWIYSRAWINTPLVQLLPLGAVTLTLCSTLIPIGLGVFIRYKYNRVADYIVKVSLCSLLVTLVVLFIMTGTMLGPELLASIPAAVYVVAIFMPLAGYASGYGLATLFHLPPNCKRTVCLETGSQNVQLCTAILKLAFPPRFIGSMYMFPLLYALFQSAEAGVFVLIYKMYGSEILHKREALDEDDDTDISYKKLKEEELADTSYGTVGTDDLVLMETTQTSL
The following text describes a protein:
Function:
Probable transcription factor required to initiate organ founder cells in a lateral domain of shoot meristems. Involved in leaf formation.
Subcellular Localization:
Nucleus.
Sequence:
MEGSSNSPDRQSSGGSPEERGSGGSGSGGRGTGGEPVRSRWTPKPEQILILESIFNSGMVNPPKDETVRIRKLLERFGAVGDANVFYWFQNRRSRSRRRQRQMQAAAAAAAAAASSAAQSSPAASPTVGLPSGAVQYPLAMGGSACQYEQQASSSSSSGSTGGSSLGLFALGPGVPGTGAGYFQASCGASSPLASGLMGDVDSGGGNDDLFAISRQMGFAESPVAASSSVAPSTAGHQQQYYSCQSPAATITVFINGVPMEVPRGPIDLRAMFGQDVMLVHSTGALLPVNDYGILTQSLQMGESYFL
The following text describes a protein:
Function:
Involved in 5' and 3' splicing site selection of introns, and may bridge the 5' and 3' components of the spliceosome. Isoform 1 is required during flower petal development and isoform 2 is involved in root growth. Negatively regulates glucose and abscisic acid (ABA) signaling during early seedling development. Involved in the RNA-directed DNA methylation pathway. Modulates KIN10 stability in response to sugars, probably through the splicing regulation of 5PTASE13, a protein implicated in the proteasomal degradation of KIN10.
Miscellaneous:
MISCELLANEOUS: The splicing pattern of the pre-mRNA is regulated in a tissue-specific manner and by development, and changes in response to various types of abiotic stresses.
Subcellular Localization:
Nucleus speckle. Nucleus, nucleoplasm. Note=Colocalizes with spliceosome components. During interphase, present in both nuclear speckles and nucleoplasm. Nucleoplasm-speckle shuttling protein. The intranuclear distribution and mobility depend on the phosphorylation status, ATP and transcription activity.
Sequence:
MAKPSRGRRSPSVSGSSSRSSSRSRSGSSPSRSISRSRSRSRSLSSSSSPSRSVSSGSRSPPRRGKSPAGPARRGRSPPPPPSKGASSPSKKAVQESLVLHVDSLSRNVNEAHLKEIFGNFGEVIHVEIAMDRAVNLPRGHGYVEFKARADAEKAQLYMDGAQIDGKVVKATFTLPPRQKVSSPPKPVSAAPKRDAPKSDNAAADAEKDGGPRRPRETSPQRKTGLSPRRRSPLPRRGLSPRRRSPDSPHRRRPGSPIRRRGDTPPRRRPASPSRGRSPSSPPPRRYRSPPRGSPRRIRGSPVRRRSPLPLRRRSPPPRRLRSPPRRSPIRRRSRSPIRRPGRSRSSSISPRKGRGPAGRRGRSSSYSSSPSPRRIPRKISRSRSPKRPLRGKRSSSNSSSSSSPPPPPPPRKT
The following text describes a protein:
Function:
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MKEAVSLNQAIDRLKVLRDSGLRQSQEVVELAEVILGTAGRTSRLGDDLWTVYEQVAVAALDVGNVELAKTLIQRLEAKFPKSARVTVLHGMLMEAQGDLLGAKSFYEQELEKSFSPKNADLGSVGELNMRVRKRLIALHLHHSPPTCPQASQPSSSSSSTSSTPFSLHTAIQLLVDHLDTVYSDPEGWLQLADIYASLGLYEQSLSALEDLILIQPENTFHILRYAETAYTAGEYELESKGGPCRRAALGLKVCIQRLPKSSTRQEIEKVIDEALVTCYSQDWVPLQPGLRVASEPCRKVLKTFLTQHSSSS
The following text describes a protein:
Function:
Required for endoplasmic reticulum integrity. Regulates the distribution of TOR1A between the endoplasmic reticulum and the nuclear envelope as well as induces TOR1A, TOR1B and TOR3A ATPase activity (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus envelope.
Sequence:
MSQTLKSQDTNMSDSGYRDPVEDSQNVLGNDPSVNSQAQDPIVTPSNTVEAQTLHPTSDLKEDHHEIGAKGQEHADTGDRAESSEEPALEKPPLDKAELERSPSSQDTEQRHHPYSEHVGGDTLVLDPNYSQSDLGGRADAHLESSSAAPTEGAGEGGEAGAHLESSCAALPVGADEGGRANAHLESSSAAPTEGAGEGGEADVHLESSSAVPPEEAHLESSSAAPSEGAGEGGEADAHLESSSAAPSEGAGEGGETAQNLLAVDSTDAQSPCHSSAGPGSQDSLRRRLPVTEAERHEEETQLVTEKEEVAQETLRKTEKKSLWTYGSMFLGCLIVAVVLSSVNSYYSSPAQQVPQNPALEAFLAQFSQLREKFPGQSAFLWQRGRKFLQKHLNASNPSEPATVIFTAAREGKETLKCLSYHVANAYTSSQKVTAVSIDGAERALQDSDTVKLLVDLELSYGFENGHKAAVVHHFESLPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEETLEASVSPRETEEKVRDLLWAKFTDSGTPSSFSHMDSDKLSGLWSRISHLVLPVQPVKNIEERGCLL
The following text describes a protein:
Function:
Possesses 5'->3' exoribonuclease activity. Acts as an endogenous post-transcriptional gene silencing (PTGS) suppressor.
Sequence:
MGVPAFYRWLADRYPQTVSDAEEEEPVELEPGAFVPVDPRRPNPNGLEFDNLYLDMNGIIHPCFHPEGRPSPTTYDEVFKSIFDYIDHLFCLVRPRKVLYMAIDGVAPRAKMNQQRSRRFRAAKDAADAAAEEERLRLEFEAEGRNLVRKEKSEAIDSNVITPGTPFMFVLSSALQYYIQLRLNHSPGWQSVKVILSDSNVPGEGEHKIMSYIRLQRNLPGFDPNTRHVLYGLDADLIMLALATHEVHFSILREVITMPGQHEKCFLCGQVGHLAAECQGPGPADNVVELPPIHKKKYQFLNIWVLREYLEKDLEIVDPPFKINLERILDDFVFLCFFVGNDFLPHMPTLEIREGAINLLMNIYRAEFKPMGGYLTDGGEVLLERVEHFIQAVAIHEEQIFRKRARIQKAYENNEDRRRAQGDISEENQYVDMVKLGEPGFRERYYAEKFREEAESKPIDQVQRDVVQKYVEGLCWVMRYYYQGVCSWQWFYPYHYAPFASDLKSLTEFEITFFLGQPFKPFDQLMGTLPAASSNALPKHYGDLMTDPNSPLNYFYPKDFEIDMNGKRFAWQGIAKLPFIDERRLLAETQKLEDTLTEEERFRNTTMFDIIYVRETHPLSAHIALLYQMYSQQMITDPSYCLPIDPAASGGMNGFLCLSQRNWYSISVESPVKGFNGITNNRVLNATYVSPQYHKHIPEPPEGVIIPPKILKPYDFKPFPILWHEDNSRRQTRDRPQVHGALTGSVLGEAAHRLLKNSLQIKSGSSAGLLHVPYGAAPYGPGHRARPSGPLGYERGFVDNPYHAHMSRSAPNPRPQFFGEAQPNRQNVRILERPNNRSRDAGIHSGMSKLAIQDGPRMQQNHRMQGPGYFPNQPYPNQYAGFPPQRPMQNNNFTQQRPVQNAGFPQQRPVQNAGFPQQRPAHNAVFPQQRPVQNAGFIQQQQAVNGVPPPFPPSTWIDKQPSGGQAGTPAKQDPRTNRHPKPKQDNLRSQHESRHQAAKVMYRVKGQAPNDLPE
The following text describes a protein:
Function:
Required for the insertion of some light harvesting chlorophyll-binding proteins (LHCP) into the chloroplast thylakoid membrane. Required for the insertion of LHCB1, LHCB4.1 and LHCB5 proteins into thylakoid membrane, while it is not required for insertion of proteins PsbX, PsbW and PsbY.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Domain:
The C-terminus (339-462) is required for interaction with cpSRP.
Sequence:
MARVLVSSPSSFFGSPLIKPSSSLRHSGVGGGGTAQFLPYRSNNNKLFTTSTTVRFSLNEIPPFHGLDSSVDIGAIFTRAESLLYTIADAAVVGADSVVTTDSSAVQKSGGWFGFISDAMELVLKILKDGLSAVHVPYAYGFAIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQRYAGNQERIQLETSRLYKQAGVNPLAGCLPTLATIPVWIGLYQALSNVANEGLFTEGFFWIPSLGGPTSIAARQSGSGISWLFPFVDGHPPLGWYDTVAYLVLPVLLIASQYVSMEIMKPPQTDDPAQKNTLLVFKFLPLMIGYFALSVPSGLSIYWLTNNVLSTAQQVYLRKLGGAKPNMDENASKIISAGRAKRSIAQPDDAGERFRQLKEQEKRSKKNKAVAKDTVELVEESQSESEEGSDDEEEEAREGALASSTTSKPLPEVGQRRSKRSKRKRTV
The following text describes a protein:
Function:
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
Subcellular Localization:
Nucleus.
Sequence:
MSTLSLLVEASSCSWGKLACQHGDRTIGIILRAIVSFCNAHLGQSASNQLLVFAFGRNVEKKLIYSSARSEDRNVSSVVVDHLRDLLQSDSGNSDATMGAPIGPALAHAFCHMKKDSQLATADICDDSLGPAASNTEKSDSSTEKVSTRAVVISMTPIIGSEHGSLMNLFFSAAKQSICVDVVSMSDDLTGGILQQAADITGGSFVHAEKPQALLKILMTNMLTDASYRNTFSKLSYCSVDYRASCACHHTLVSSGWVCSICLSVLCQYTPICKVCKAAFTITNLPKKPSRKRTLRS
The following text describes a protein:
Function:
Required for pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MEIQSSGRSIEGLMDKVLSVNILSSDYFKELFKYKTYHEVIDEIYNQVDHVEPWMTGNCRGPSSAFCLLYKLLFTMKLTVKQMHGLLKHQDSPYIRAEQIYLLILHARR
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MGIPESLIDKLKLEFNALAPTEAQSVLFPAIMSHKHTILRDNTGTGKTLGLVLAMLTKPHPSVFSLRQTSRPHSFTNALQQPIIPSELASYNNTSDDKESLLKNETESLQAQKLLLRKHKYLTTLMIVPTRELAIQIVSWMRRLTASITQGNTDAEASIFQCVIAGVDASEQAAQLKRINPRILVGTPQRLFELHEQKAYDTSRLQLLVVDEVDRIVNAPSRYEPIKKKIQRQVHPLSGETLIAKISEQRKAMQATMDTREKHISHTAALSRYHRPQHVKKGKASMSESGIAESSVRFDPAQARPLQIIISSATSNSTIKNYMMKTKGWMPFATMLEMNTTTRIPATLKHKAFIVDRLGNANQLGNHSLNTNLQSQRIQNLDPITTVSNVTTTTNLSPVLPSLIPNTFIHKENTFKDVKLEQKAPLQEVLADDHDLMVETVADFILRENITKAFVFGRASMSVTKLVDRLKALGVKADKMFNLVNYKGIGTPGIEFNDASDSDSLVESASGSVPFQRFHDGQVHVICATEYEARGLDLPDVSHVFILGVPSSDANYVHMAGRASRFGREGHVTTLLGGQRLLVKYANMIKKLHIELDES
The following text describes a protein:
Function:
Modulates RecA activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MSNIITKIEVQKRNKDRVNVYIDEEFNFACSSELIYYHNLKKGKVIDQNSLNDIIKEDNYIKAKGYALKYIEKSLKTESQVKEKLYLKEYDEDTVNKVIRFLKDYNFIDDDKYCDMYIREKLNIYGRNKIKYTLLNKGVKENIVIEKINNINEEKEKKVAYKLAEKKYKIMILREKDKFKIYKKIWPYIISRGYNSNIAEWIINELKSNEALYKDNSICLDEQNMKLSQNIENNIKDENIEKFHNNSSFNSKNNSYKENIDILARKRYDIIIKSEDDKNKIYRRLSNYLLRRGFSFEEVKKSTNRVLYERE
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity).
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MATSLTSQLENLRTSAARHLTVEKRHVSLLFDRKEANKLSNETAHRIGVAGLEQMKRIDPVFDTEFANDLFSEERVDFVRSMLEKGANEELNKQIEKLLLELSPYLQHFACQQVLEFLIHTYQIYSFNAETLLLTFLPFHETKVYSRLLRILDFDWKRSKEWQFMQQFTKTETPIPFTSIARATLSSKHSIITCITDHIRHAVEIVGSDYLEIKHPILFNFHAKLLLSMFTDPEKVDEMMLAKLMPFIENGIKSPMKSFRYSAMVVISQLVLTVKLKDEVLNSMCKLLITKMRSDTAAASLSTLMVVFQQQNVQSLSKNTLKKLLRHEEGIDVWKILKELSERTDTTKFFNVLWKELIVLSKDAESEDNTLAIDVLIETIEDASILTGDQAGTILKLILQEGMDGNIFDNKKKLKSNIRAIGMRFAKQFDAIHAELKAKDKKTLKNVLKEYQIEDIVQFASEAVAATQSEESIEIISEEAPSSKKIKLTASEKAQKLAQSSEFAKREVFSGDPINKATEWLNGEKWDKVEWALNEMAQRGEKYFSRKVEDDVEQFVLEIVKVVGVGGVKQIDGGSVKAALAGANLNPQFVADLLTKFDGVSEIAPKRTKGAQKKNLVEKTFGTEESWEAFNQRVVFVLDLLNARQIIPSSEKVLAALFAVVKQVNSKSDVESSSYQQHLAVNAIRKILEHPEKTKIGASEVDMDCVIETMRSTHNHHLLRDCLRLIVAAAKHTPNSVVKHVMSVFTFMGNGMLRKDNELTLSIVEKTVESLFSTIINSSGQAVLTKQQQTEKLIELARLFAASAIDIPAHRRARIAQAIARAVQAENASTVVLVLVSSFCARWQRSSDAAAQEAMKRGSDQDAYDDLAIELLSALNPFEQLSSVLEMCEYVRRLGGDKPAKSTTTKKDLDTMIFDRTAQTLPRIRHFRYVVVTLISRIFSNRVLIERLAAYDDEELLKNALPLGKRLIECSVELDEFANKEANDQDGSDPQAQRYWVAFASRTEVVSEKLRHLLPGGVAARLIADVLQECVNDKKMSYKMCEKVLQLANIKLGHDRYLFADSGINEKELITLAQALNKFIVAETKSEEKMRMCQNSAYTLKLIAKNLPSQSESLVLADTMQRCVSIVSQYQKLDENLTGNVLLLAGELIRSHNMRSTIHHATSLLKTCLATVQECIARFSKPQYDSAASPGSSVAGGRGNRGHRIRQQSLGGNKFGSDTLLICSLTCIQRVYDQFASFVVESTGDVIIRYCRLIARFGDPSELLALNQPSSSTTAAFQGGSQTSGFGSKTGIHHRLSLIRRSLLSIELRVLPAHIVKTVGELKTEKKALSALFNLLTGYIETQHQQKPEILRKSVIQLRRTFVSDVITPTLIVRSQERQSDQFENVEKLEHTVFNFVISIASILSEVEFRTVVNELVAWAEPGLEAKADLAARLRLVSLLHFANDLYTSFNSLALPYFGRILEISALVLKKCNATLLLGTDELLLSGKRGSIEALETDLALTLAIDVISNAARHRDFFTVDRCQLVSDVIVNELVNTKVEGHEKRCSDHLVPAIYRIGNADPDSFPELLNKIMLKTRDSRAKIRYRALIVLELLIKEIGDGVQPHLSILLPFLNELIEDENKQVEAQCQKVINSLQHKFGETFWSGGSSA