lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
Subcellular Localization:
Nucleus.
Sequence:
MWKESLAFKFGESVQYALQLQHRMLGCNSKNPDILRSSLPPKWRELTLRSPDPSPSDGVLLLPPITSAFHAGLCGGDECAPTQTSCSRQYTTMALSQMLIEVIFLAATVDALQNHCHQCVASRRPFARSIKNSSIDAPLAFVHSPTQRMTHVISSSITTLHASVDVGTTPSATTSEDGIVSPSLPLAQQFLTSYEQSLEEGQQWANEFGFADGSEGELSSEGAFYSIFRAFRKMDHDGNGELLGLDGTPFYIPSSLLKNAESEFSSKQQLSNGGEKNAFTSYFNFQHLATALEEDFLDAQRGSTDNRKGWQVSAVSQPTGSSFDDARMTLPQVQTALTAGTVIFNNIGAHIPRLAGPTLACTDALSLPGALNMYVTAKGMRTSAPPHTDRQDVVVIQMEGAKRWRIFTPPTDGEVKPTADPFARGKGEDSLPLHTLLEGKEGRLGTELLMDVVSREGDVLFIPAGFPHTTDTVEETTADKTDSSVNTEYDTSIHLTFNIDTHVWDLDYLNVRNVAMRRNGVRDVLLPSLSSGERNRYVGNVNKLPSDLRSRLMDALPLDFLDLDPRSNPDSVNLVVKRVEELAAEVDNEAATISSESFREALNRVHEYSSKILDIHRDMYLAAIEEGRLRKSETAMTAHLKKDVDGSDSPIVSMTPERIQRLSLFRVRPFFEAIDVAKKDFERWCVSEASIAQSSSSVSSSGSVTTQLDSNWQYTSPLKVGDEVEADLGGAFFAAKVSQVVGNTYNVVFFDGDRSDGLSRDQVKLLTPPKTSDEIDTTGLTPKEIKRLKKKMEKKQRK
The following text describes a protein:
Function:
The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.
Sequence:
MYRLRTTAALALARTAGTLSRRLGLGGGTSLPGQVARILDPTILTNFCTALPEGVALIAGTNGKTTTSRMVATILEQAGKPLLHNRAGANLLPGLTTVAIADADWRGRPHAHQALFETDEAALPQAIAETRPRLVVLLNLFRDQLDRYGEIDTIASHWRTALQTLPPTSTVVFNADDPALASIVQGLSAQIIAFGLADVRQATGAALHIADSQFCHVCGHRYHYQHVFYAHIGHYACPQCGQHRPEPDIALTVLEPRGLDGSDLQITHPGGTVQFRLPLPGLYNAQNALAATAATLALGITPATISSALQNFQAAFGRIERITAGPNGPPLLIALIKNPVGASETVRMFTTATDQPLHLLIAINDRFADGTDVSWLWDADFEPLAQRVAHVTVSGTRAADMALRLDYAGVAGEVITVIDDLPAALDAALSRLPPGETLAVLPTYTAMLDLRSEISRRGWAKPFWEA
The following text describes a protein:
Function:
Orphan adhesion G-protein coupled receptor (aGPCR). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRG5 is specifically coupled to G(s) G proteins and mediates activation of adenylate cyclase activity.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDHCGALFLCLCLLTLQNATAETWEELLRYMENMQVSRGRSSVFSSRQLHQLEQMLLNTSFPGYNLTLQTPTIQSLAFKLSCDFSGLSLTSATLKRVPQAGGQHARGQHAMQFPAELTRDACKTRPRELRLICIYFSNTHFFKDENNSSLLNNYVLGAQLSHGHVNNLRDPVNISFWHNQSLEGYTLTCVFWKEGARKQPWGGWSPEGCRTEQPSRSQVLCRCNHLTYFAVLMQLSPALVPAELLAPLTYISLVGCSISIVASLITVLLHFHFRKQSDSLTRIHMNLHASVLLLNIAFLLSPAFAMSPVPGSVCTALAAALHYALLSCLTWMAIEGFNLYLLLGRVYNIYIRRYVFKLGVLGWGAPALLVLLSLSVKSSVYGPCTIPVFDSWENGTAFQNMSICWVRSPVVHSVLVMGYGGLTSLFNLVVLAWALWTLRRLRERADAPSARACHDTVTVLGLTVLLGTTWALAFFSFGVFLLPQLFLFTILNSLYGFFLFLWFCSQRCRSEAEAKAQIEAFSSSQTTQ
The following text describes a protein:
Function:
Plays an olfactory role that is not restricted to pheromone sensitivity.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MRLPVKIAIGCAIGLVVIIVFGFIAFPKMIKGKVKSMINLNKGSEIRQMFVKVPFALDFKIYMFNVTNPMDVQKGALPVLKEVGPFCFEEWKEKVDLDDNDDEDVMFYNPKDTFYKANGPGCLDGSQMITMAHPLILGMVNTVVRTKPGAISLISKAINSIYGNPDSIFMTASAMDILFDGVVIKCGVKDFAGKAVCSQLKEAPDLRHVDENDLAFSFIGPKNATPGKRFKVLRGVKESHDVGRILEYDNKKEMEVWPTKECNQYKGTDGTVFPPYLTKEEGLASYAPDLCRSLVAVYSGDTKYDGIPVRIYTATLGDMSKNADEKCYCPTPDTCLKKGMMDLFKCAGVPVYVSLPHFYESDESYVKGVVGLNPNKKDHGIQILFESTTGGPVKAAKRLQFNMPLEPNPKLPIFANLPNTVLPLFWVEEGVALNNTFTKPLKDLFKIMKIVKIAKWLIMLGCLGGLGAAGYLYFSKKGEANITPVHKVKPAENGVSTLGGEVNHAMSDNEIEKY
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC).
Subcellular Localization:
Nucleus, nuclear pore complex.
Sequence:
MEPQGPEPMTLGSPQSSSTSLPGSLSSQFLPAFLIGDQSPAVSPALGRQRSLLRSPSRSMTPSTLGPRDSLHRADSSDSRVGQTPRTASQVSHTPKDKGNAPPVAGLYDPIQDHRGSPAVFDTPERRQLDFTQAPSRTPRQLDSPAASRLFSPSQQSMVQSNQWSMQAPPSPPQVDPFYTQGENILPEDELDDTWITIFGFQSAATSYILQQFSQYGNIVSHVVASSGNWMHIQYSSHIQARKALSKNGKVFGGNVMVGVTPCIDKGVMSGGTSDSYGVNTTGSMDTPITPAKRLVSQNAEPEAVRRTPIRPLTAAYKAASNPHEVVQESRTPQKSSNVVSKTLEYMFGW
The following text describes a protein:
Function:
Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MATKLVQWLTVFFLVASIWSALLFDLIPIRLDDTLKEVIWPFPAYFLVVFGCFSLGTIGYRVATFNDCEDAVVSLKEELEEARKDLASKGFTFS
The following text describes a protein:
Function:
Neuropeptide with neuronal depressant and sleep-modulating properties.
Subcellular Localization:
Secreted.
Sequence:
MGGCSTRGKRPSALSLLLLLLLSGIAASALPLESGPTGQDSVQDATGGRRTGLLTFLAWWHEWASQDSSSTAFEGGTPELSKRQERPPLQQPPHRDKKPCKNFFWKTFSSCK
The following text describes a protein:
Function:
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
Subcellular Localization:
Cytoplasm.
Sequence:
MLPPGADSVVVRHGDVGVKSSHVQSDMERTLRDNVAAMLADRGVPGDVEREWGRVLVRSPAPGRAADAAADTFGVVSASPAVSVAPDLDAISDALAAAARAHYDGGAFAVDARRAGTHDFDSHDVNRVGGDAVWAAVEDDFQPVVDLDDPDITFFVEVRDAEAFVFLTHRDGPGGMPLGTQQPLVALVSGGIDSPVAAWESMRRGAPVIPLYLALGDYGGPDHRARAEAAVRTLDDYAPNHDLSLRVAPAGDAIDRLAAATGRTRMLSFRRFMYRVAEHVAEHAGAAGIVTGEAVGQKSSQTTANLGVVDRATTLPVHRPLLTWDKQRITAAARSIDTFRDSSLDVGCNRLAPRQPLTAAPIESVRADEPDALFEWARAVAADTGPVEVAVA
The following text describes a protein:
Function:
Catalyzes the GTP-dependent phosphorylation of 5-hydroxy-L-lysine.
Subcellular Localization:
Cytoplasm.
Sequence:
MDVTSVQHVVRELYAVSTITVKQLEGYADSNYYISAQPNQYSCTEFVLKIIHMENESVKCQYHAIGCSLQHLHKQGVQVSKLIPTVDGEMLGSYDFNDNACACGVMLLTYIQGQTLCEVVVTQLHMNDIAQQSGKAIAQIDEALSTLHLSDELQLKGEWNLLNLDFVKSCSHYMRCNKTKDLCHRVFNLFEDKVVKNLNKLQTGLIHGDANDANLILKQQPGCGRWIIEGIIDFGDMAHSFYLFEIAILVAYFMMKAFKDGLDADIVADHVLKGFKSVLRLNPFEHEVLYVTVAEVAAHSLCKTAADAQKSPDNYDYIIQDYDAFEKLLSHICDTNITNRM
The following text describes a protein:
Function:
Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation.
Sequence:
MDFNKMDDCTSPLTLEFYIFLLFGMSLPLIFFFLITKRSRNQSNACWRLLQHVFQEAIQSESLPELHEILAIQGPDITTLPATSLDEHETTAMLTAIQNGSCEVVVFLRELGVDVNLHGTFEWRGAKYDNVSPLCAAIISRQADIVDEFVVVEEEQLDAVTADMEGIKTSSIPTEQKIEALELMGAAYVFYRYSPSLVSSSYAISIWKEATRLRFSTVDGEQAIPKTISPPSDLFAKAMGFTSEFLTLEHLEQIEAQLDFDNDYLELNLYTQALLVIHRILDQSDPEQHKYILLQLCNHADRLHYEDHYNRAINIGMFMLDEFQGFEEWDDEVNDIIIKTIGILVESFAKLKDVPSSEFTFTNVMTTLENTLKVNHNSVNISEYQEFDLLIFDLIDFITEMLPTLSKEESHQFKQIVYEFIRADYRFDRVDKGNILHLACCNLFADLIGPKRFRINLMKLLLELDVDPNFTSTNGKTPLHILANSFQWERWSETTNITDAVQLLLDSGANIDQPDGEGRTPLDLFKLRKRIE
The following text describes a protein:
Function:
Required for sporulation.
Miscellaneous:
MISCELLANEOUS: Present with 656 molecules/cell in log phase SD medium.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MSYKANQPSPGEMPKRSPSILVTDARTSKNRMSAPFAGHAAGSRKNMENAGVTKSQGVRSSAIGPSPLQSFTHPRRRSSGRFSDISIDNILSDNSDIPSARREERLSSSSSDRPRQYERLSSRRKMINPLPPRTSKTSQKLVLIPEDDNLNHFQTLPTNALDRQRPKVGSMKSNSFDRLPRYSKEKSMARITAYNVADGFNLNQLYKFLQETHEVSPRLYDECLYVAYTLPLLPGKGGFRIKSNLSKKTMGGKTLIDNLIDTSEQRDHHYEYYSGVETVEDANNNYELETSGNNNNANQDTTTVPDHLPNPVGQQDSFNPMEPQFFAEETPLEIEKRERTERINMLKKEENDSDASCGNDNNNKNNDKSKLYAVEGNDQYVQSSRSPASPSSISTPSPPSSSQNDFDRVYKMHRDNDHEGNDRHAEIFIFHYGVIVFWNFTEIQEKNILGDITFADYKNLMIRPLDEQDIETEQFHFEYDRDTERPRIFNDIVTLRSGDHIIELTLSHAIAQSSKLSRFESRISPILISVTKLPKRLALYGTLGLKREQLLKKSGKLFKLRVDVNLSSTILDTPEFFWSFEPSLHPLYVAMREYLEIDQRVQVLNDRCKVFLEFFDICVDSVAERNMARVTWWFILVILFGVIFSLTEIFVRYVIIHRHTST
The following text describes a protein:
Function:
Catalyzes the hydrolysis of glucose from the disaccharide unit linked to hydroxylysine residues of collagen and collagen-like proteins.
Sequence:
MSMRGSGKLWLVMADGQEDPAVFTSTCLPSDSRLLATVTNAYLGTRVYRNILHVSGVYNGAAGDTHRADIPSPVNVRMTVPDGDVPVETFTLNTRTGTFSHKLESSSYTATHQIYAHHSLVHLMAFSITIWRSAGTSQPITVQLQAPFVPKSQDLDLQQGPDFQGAHYIYGQTLVPEVEGGPQPTVHMLWTPVPQAVTLHEEEQERRWEFLTAVAESEEEAKRSYSEGLARMAAGSLHSSHTRAWAALWRGCCVDLEGPLPLRQALYGCLYYLLSAIPPQGTPGFHFHGISPGGLSNGTRGEDYWGHVFWDQDTWIFPNILLFYPEAARAILEYRIRTLEGALLNAQEQGYKGAKFPWESAATGREVCPEDIYGAQEIHITGDVLMAFEQYYHTTQDQKLFRTDGGWELVSAVAQYWCSRMVWSEEEQCYHIRGVMPPDEYHYQVDNSAYTNAVAQRSLNFAASVARDFFIPVPEEWVECAKKVKVPFDAVRKYHPEYDGYSPGEPVKQADVVLLGFPLMHPMHPEVRRNDLVMYEPVTELSGPAMTWSMFAVGWLELKETQRAQGLLNKCFSNITEPFKIWVENSDGSGAVNFLTGMGGFLQAVLFGYTGFRITKTNLRFDPAFPSDVSKLEVTGVSYLGSKLKFSITKEKMRIAVTKCPLHPPLEAVLEESGQRFPLHEGQSISFPTAAGCIQKAPSEGL
The following text describes a protein:
Function:
Together with PE10, induces macrophage apoptosis through human Toll-like receptor 4 (TLR4) signaling pathway. Interaction with TLR4 leads to increased levels of phospho-IRF-3, increase in the transcript levels of IFN-beta and pro-apoptotic genes, up-regulation of IL-10, down-regulation of IL-1b and enhanced levels of macrophage apoptosis.
Subcellular Localization:
Secreted, cell wall. Cell surface.
Sequence:
MSYMIATPAALTAAATDIDGIGSAVSVANAAAVAATTGVLAAGGDEVLAAIARLFNANAEEYHALSAQVAAFQTLFVRTLTGGCGVFRRRRGRQCVTAAEHRAAGAGRRQRRRRSGDGQWRLRQQRHFGCGGQPEFRQHSEHRR
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MAFVVRSGRLAGPLRNYLRPIAIGNRCISTSKKKDETAVVTEKIPSHKVTHDIDVAAASARKKWMTYGFTTQDETEDVALAHLFSLFGITLCIVIGSLAYMYGPDHALRDWSQREAYLLVREREAKGLPLLDPNYVDESTVVLPSEEDLGAYEIII
The following text describes a protein:
Function:
Involved in the biosynthesis of sulfolipids in the chloroplast. Catalyzes the first committed step in sulfolipid biosynthesis. Converts glucose 1-phosphate to UDP-glucose, the precursor of the polar head of sulfolipid. In addition to glucose 1-phosphate, can use galactose 1-phosphate, but with much lower activity. No uridyltransferase activity with other hexose monophosphates. Specific for UTP and cannot use ATP, CTP, and GTP.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MANPQASPILHHPQNHLSLFHFRTTTSPRSFSSLHFRKPLLFLSSSSSFSSKLQQSEQQCNNHQVRHVSTVPVEYSTPTPPESDDFLSEIDRLKSLLSKLDVSKDLRRKDAVIDADSRVRRFFSENRGGLSKVFGYLGLNSNEMFLVKCVIAAGQEHALCMNYEEAFGEEEEEYTVRSSVKNALYALVEMIERFDVNSSGYKGRREMGTVLDSEEIAHFRKFLTFLEEIEQFYDCIGGIIGYQVMVLELLHQSSKRRNTNRSQLVEESLGCQYLEMHTPSVLDLTQEEDYASQAALWGIEGLPDLGEIYPLGGAADRLGLIDSETGECLPAAMLAHCGRTLLEGLIRDLQAREFLYFKLYGKQCVTPVAIMTSAAKNNHEHVSSLCERLKWFGRGQSNFRLFEQPLVPAVSAEDGQWIVSKPFVPVSKPGGHGVIWKLAYDKGVFNWFYDHGRKGATVRQVSNVVAATDVTLLALAGIGLRYNKKLGFASCKRNAGATEGINVLMEKKNFDGKWEYGISCIEYTEFDKFDISNRSPSSNGLQADFPANTNILYVDLHSAELIGSSSNAKSLPNMVLNTKKRIEYLDQYGDYHSVMGGRLECTMQNIADNFFNKFPSRCHGSLEDKLDTYIVYNERRKVTSSAKKKKPHASAALHQTPDGALLDILRNGYDLLTECDIKLPMIEANDKYVDSPPPYLILLHPALGPLWEVSRQKFKGGSISSCSELQLEIAEFSWNNVQVDGSLIVTAENAMGSTTPNDNGEPILQYGLRCGKCKLHNVNVVNRGIDWNSKSNVYWRNDVNRLETCKIILHGNAEFEASNVTIEGHHVFEVPDGHKLKITSGNAGLSINLEALKEEVMETGSWYWNYQLNGSHIHLQQVEVSQS
The following text describes a protein:
Function:
Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
Sequence:
MKLSDLISRWIDVEPSKNAQIILRDRYFMKDLDGNYLETKWEDVARRVARVVATAELLNPSYKKNEKLDRIKEWEDIFFRVLKARLFIPNSPTLFNAGLGVKHDLLWKPIDQMTLEDYEEIYRSRNHLHMLSACFVVPVGDSIEEIFEAVKEYALITKVGGGVGSNFSELRPKGSFVAGTHGKASGPVSFMHVFNSAISVVKQGYRRRGALMGILNINHPDIEEFIDAKKENTGEAVLNFFNLSVGFPMDKKEILKLYEEDGELELSHPRSTIRKKVKIRELFRKIATNAWKSGDPGLAFLGEMNKYYPLYPHRKINSTNPCGEIGLSDYEACNLGSIDVAKFYNNGFVDLEALQELVQIAVRFLDNVIDVNVFPIDKITKAVKESRRLGLGIMGFADLLYKLEIPYNSQEARDFAANLMAFIALHAHRTSYELGKEKGNFPLLEISRYRTEDNFVPFAMGMSNYDDEIREVMKMTKEFRRNVALLTIAPTGSISNIADTSSGLEPNFLLAYTRFVTKEDGTKEPLLYVNQVLREKLNPEILKRIEKELIEKGSLKDIPDVPEKIKKVFVVALDIDPMDHLLMQDAFQRYVDNNISKTINMPQSATVDDVLNVYLEALRTNVRGITVYRDGSLQTQVLTKALKTPEAPKVQFFVVDEKLKLHPRPRKDTLRSVTRKYKRPDGTTYITISFDDTGEAVEIFISNGSEMAEAIGRLSSIALRAGVSIDEIVEQLSKVKGEYCKGLAEEIKKALEDFAKLWLRTGEEAPESEEEPIEREKFIVAHNLRWQSGYYVDDEGNVYCPVCLSKNSLIKQEGCVSCKNCGWSKCE
The following text describes a protein:
Function:
May play a role in hearing.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein. Secreted.
Sequence:
MGHICGGSIVNSQWIVTAAHCVTTKPPGASRYTMYAFSDLNVTLGEHQLYQLDGSEQNIPIEGIVVHPSYNDLDYDIALLKLRQPITFNAYVSQVCLPQDALLAGTPCYVSGWGRIGESSPGSNVLQEASIPLVDQRACEEQYRNLKPITARMRCAGIYGTPKGTCKGDSGGPLVCESKGRWVLMGVTSWSYNGCADSGYAGVYADVVYFKDWIRQTVST
The following text describes a protein:
Function:
Involved in mitochondrial potassium homeostasis through the mitochondrial K(+)/H(+) exchange regulation.
Miscellaneous:
MISCELLANEOUS: Present with 11300 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MLKYRSLPIKRAIHHPAPGITPISPRIMVSRLRVIPSFNLKFNRWNSSVPESSKKELKTTDGNQESASKVSPVKEKEKVPFKVKMQKALRHYWDGSKLLGLEIKISSKLLMKSAAGYPLTRRENLQLKRTTQDIVRLVPFAAFLIIPFAELLLPFALKLFPNLLPSTYESSKKRENKLENLRNTRKLMSEIIKNNKSHFKPNNISEEQKALFNRFYTHVRATGVPESRQQLIEVARLFTDDTVLDNVTRPYLIALAKYMNLQPFGTDVMLRYRIRYKMLELKKDDLSIYYEDAEQLSLSELKTACASRGIRSVDVEPSVLYSNLRLWLNMRLKDKIPSTLLIMATAYNYGNVQSKESLYDALCDVLIGIPDELYHEVKVNVVKEDEASAKQKLKQLREQEEIMKEEEQQEENAIVSVKDELSLDDQDKNIDAAAPDVKPHDTKPIGEAAAIKEK
The following text describes a protein:
Function:
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species. Prefers NADH over NADPH as coenzyme. Is also able to catalyze the reverse reaction, i.e. the NAD(+)-dependent oxidation of G1P but not of G3P. Does not possess glycerol dehydrogenase activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MNRIAADVQRAFENAGEKTLPIKVEEIVLGKQAADSLLDYVKRKNNQHIVLVCDANTHRIAGIDLENRLNQEGFQAECLIIPENEAGDVTADERSLIHVLIHTKQPTDVMIAVGSGTIHDIVRFAAFQRDLPFISYPTAPSVDGFTSAGAPIILYGTKTTIQTKAPSALFADLDLLKAAPQSMVAAGFGDMLGKITSLADWEISRHLAGEPYSPAGAKIVQEALAACIEHTEDIAMKTETGIRVLMESLLVSGLVMLALDHSRPASGGEHHISHWIEMELMEKKRPQILHGAKVGCAAVLLTDTYRKLAQDDGLNEFSPSRREAIQSAYQTLPRGEVLADWLRSAGGPAYFDEIGVGQDSVKNAFRHAHTLRDRCTGLRIINENKTLINHGLYE
The following text describes a protein:
Function:
May function as an ATP importer.
Subcellular Localization:
Plastid, chloroplast membrane; Multi-pass membrane protein.
Sequence:
MEAVIQTRGLLSLPTKPIGVRSQLQPSHGLKQRLFAAKPRNLHGLSLSFNGHKKFQTFEPTLHGISISHKERSTEFICKAEAAAAGDGAVFGEGDSAAVVASPKIFGVEVATLKKIIPLGLMFFCILFNYTILRDTKDVLVVTAKGSSAEIIPFLKTWVNLPMAIGFMLLYTKLSNVLSKKALFYTVIVPFIIYFGAFGFVMYPLSNYIHPEALADKLLTTLGPRFMGPIAILRIWSFCLFYVMAELWGSVVVSVLFWGFANQITTVDEAKKFYPLFGLGANVALIFSGRTVKYFSNLRKNLGPGVDGWAVSLKAMMSIVVGMGLAICLLYWWVNRYVPLPTRSKNKKEKPKMGTMESLKFLVSSPYIRDLATLVVAYGISINLVEVTWKSKLKAQFPSPNEYSAFMGDFSTCTGVATFTMMLLSQYVFNKYGWGVAAKITPTVLLLTGVAFFSLILFGGPFAPLVAKLGMTPLLAAVYVGALQNIFSKSAKYSLFDPCKEMAYIPLDEDTKVKGKAAIDVVCNPLGKSGGALIQQFMILSFGSLANSTPYLGMILLVIVTAWLAAAKSLEGQFNSLRSEEELEKEMERASSVKIPVVSQDESGNGSLGESPSSSPEKSAPTNL
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular Localization:
Mitochondrion inner membrane. Mitochondrion membrane.
Sequence:
MVAKIFKLAAVPAGLVFTSYGLYAVSDREPKGNLLKPIQLSVYSVPAQKSKYIEEHPGRLQSGLSSVRETIWPYVVWGKHFCSSVRNGVEDTVQFGKDSYVYLKNPPPEFLARLGIITVSGLAGLVLARKGSRLKKIAYPLGLTTLGISVCYPTQAVIFAKLTGRKIYTVSHQTYDTLSSLWKTSIHKEDKPQTQTEDLKIPVSVTEGDHYQGNQEEVLETLIPDLTNSTKYEDPEPLIAVETEPPALINQEILDVNEEVNLNKEGLNNQEKQTTGSSDLKNQRKFKPDPSLLDHGQAHPEDVDMYSTRN
The following text describes a protein:
Function:
mRNA-binding protein required for maternal mRNA storage, translation and degradation during oocyte maturation. Probably promotes formation of some phase-separated membraneless compartment that stores maternal mRNAs in oocytes: acts by undergoing liquid-liquid phase separation upon binding to maternal mRNAs. Binds to the 3'-UTR of maternal mRNAs, inhibiting their translation.
Subcellular Localization:
Cytoplasm, Cytoplasmic ribonucleoprotein granule.
Sequence:
MKVEHKTRPETNCLGILRCAWAPGGRMERIFCVPYSLYPGYGNMLRLGQSGLSEPRQPHWRQTNVPPTFLARPRLLMPSNASDCCVDPYKRAQLMAVFSHMNPGLSLRLRKANTKDVGVQVSLRVGKSVQCSLGPRTLDSLSPWASAGHRAPASAWGVSSSVPGHWGEVRLREELSDPPEAGQPPPPLPPPSPPPRSEEDPPEELQPREELVEEDSSSPRERKSKPAPVDSSQPLGRPNFQFLEPKYGYFHCKDCKTRWESAYVWCISGTNKVYFKQLCCKCQKSFNPYRVEAIQCQTCSKSRCSCPQKKRHINLRRPHRQELCGRCKDKRFSCGSIYSFKYIM
The following text describes a protein:
Function:
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. SSRP1 binds specifically to double-stranded DNA.
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MADHQNGGSKPSASGSGAYTIDLENFSKRLEAFYSHWGKHKSDFWSSSDAVAIATPPTSEDLRYLKSSALNIWLLGYEFPETIMVFMNKQIHFLCSQKKANLLETIKKSAHEAVGADLIIHVKAKHDDGTALMEEIIRAICVQSKSDSPIIGYITKEAPEGRLLETWSEKLGSSSLQLTDVTNGFSDLFAVKDVSELTCIKKAAYLTSSVMKNFVVPKLERVIDEEKKVSHSSLMDDTEKAILDPSRVKVKLKAENVDICYPPIFQSGGQFDLRPSASSNDEDLYYDSTSVIVCAIGSRYNSYCSNVARTFLIDATASQSKAYEVLLKAHDASVSALKPGNTVAAAYQAALAVVQKEAPELLPNLTKSAGTGIGLEFRESGLSLNSKNNRLLKAGMVFNVCLGFQNLQAQTNNPKTEKYSLLLADTVIVSEKPPEVLTAGCSKSVKDVAYSFNEEEEEEPPRVRSDMKSTGVLPSKATLRSDNQEMSKEELRKQHQAELARQKNEETARRLAGGGSAGAEGRGPARTSSELIAYKNANDIPFSKELAIQVDQKNEAILLPIYGSMVPFHVSTVKSVTSHQDNRTCTIRIIFNVPGTPFTPHDANSLKFPGATYLKEITFRSKDPRHSSEVVQLIKTLRRHVASRESERAERATLVTQEKLQVSGNRMKLIKLPDLWIRPSFGGRGRKLTGTLETHVNGFRYATSRPDERVDIMFANIKHAFFQPAEREMITLLHFHLHNHIMVGNKKTKDVQFYVEVMDVVQTLGGGRRSALDPDEIEEEQRERERKNRINMEFQNFVNKVHDLWAQPQFKGLDLEFDMPLRELGFHGVPHKSSAFIVPTSTCLVELIETPFLVVTLSEIEIVNLERVGFGQKNFDMAIVFKDFKRDVLRIDSIPSSSVDGIKEWLDTTDLKYYESRLNLNWRPILKTITEDPEKFIEDGGWEFLNMEASDSDSENTEESDQGYEPSDVEPESASDDEGKDSESLVESDEDEEDSEEDSEEEKGKTWEELEREASNADREKGDESDSEDEKRRRKAKALGKSRIPDRRDPKGAPPKRRKFK
The following text describes a protein:
Function:
Mediates the export of the majority of mRNAs from the nucleus to the cytoplasm. In ovarian follicle cells, plays a role in transposable element silencing regulation by enabling the nuclear export of flamenco (flam) transcripts and subsequent piRNA biogenesis.
Miscellaneous:
MISCELLANEOUS: Mutations affect the morphogenesis of embryonic neurons, embryonic muscle and adult sensory bristles. This is thought to be due to reduced rate of protein synthesis as the mRNA is not efficiently being exported out of the nucleus.
Subcellular Localization:
Nucleus, nucleoplasm. Cytoplasm. Nucleus envelope. Note=Localized in the nucleoplasm and at both the nucleoplasmic and cytoplasmic faces of the nuclear pore complex. Shuttles between the nucleus and the cytoplasm.
Domain:
The leucine-rich repeats and the NTF2-domain are essential for the export of mRNA from the nucleus; The C-terminal fragment, containing the TAP domain (also called UBA-like domain) and part of the NTF2-like domain, named the NPC-binding domain, mediates direct interactions with nucleoporin-FG-repeats and is necessary and sufficient for localization of NXF1 to the nuclear rim; The RNA-binding domain is a non-canonical RNP-type domain.
Sequence:
MPKRGGGSSQRYNNNVGNGGGRYNAPEDFDDFDVEDRQRRKDRNKRRVSFKPSQCLHNKKDIKLRPEDLRRWDEDDDMSDMTTAVKDRPTSRRRGSPIPRGKFGKLMPNSFGWYQVTLQNAQIYEKETLLSALLAAMSPHVFIPQYWRVERNCVIFFTDDYEAAERIQHLGKNGHLPDGYRLMPRVRSGIPLVAIDDAFKEKMKVTMAKRYNIQTKALDLSRFHADPDLKQVFCPLFRQNVMGAAIDIMCDNIPDLEALNLNDNSISSMEAFKGVEKRLPNLKILYLGDNKIPSLAHLVVLRNLSILELVLKNNPCRSRYKDSQQFISEVRRKFPKLVKLDGETLEPQITFDLSEQGRLLETKASYLCDVAGAEVVRQFLDQYFRIFDSGNRQALLDAYHEKAMLSISMPSASQAGRLNSFWKFNRNLRRLLNGEENRTRNLKYGRLACVSTLDEWPKTQHDRRTFTVDLTIYNTSMMVFTVTGLFKELNDETNNPASMELYDVRHFARTYVVVPQNNGFCIRNETIFITNATHEQVREFKRSQHQPAPGAMPSTSSAVTSPQAGAAAGLQGRLNALGVATGPVAILSGDPLAATAPVNSGSAAISTTAVAPGAQDESTKMQMIEAMSAQSQMNVIWSRKCLEETNWDFNHAAFVFEKLFKENKIPPEAFMK
The following text describes a protein:
Function:
Receptor for CM101, a polysaccharide produced by group B Streptococcus with antipathoangiogenic properties.
Subcellular Localization:
Basolateral cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Lysosome membrane.
Sequence:
MFLHRLFLQKFGEPFLALVPSTRFSLAIACFLGSAVVYMLRTSLSMAIVCMVNKQPNNDTNNACAPNGVSTAVDLFNATTAEPKKQYEFDWSTKEEGYVMSSFFYGYLFSQVLGGMVAAKFGGKRVVLGAMLLAAVFTLMSPVAARTHIVALMGMRATIGFTQGAVFPAMHSMWSQWAPPQESTVLTSISYAGTQFGNIIVLPLGGFLCMHGPDGGWPSIFYVLGLVGLLWCAVWMYMAADRPTTHPRISTAERAYILTSREATMGKASSKPVSTPWAQLLTSRAVWACWLGHFAGDWGAYTMLVCMPSFLSDVLGLELQSLGLLSAVPYIAYFIMINVGGIAADYIRARNIMTTLNMRRTAILIALIGQAVFLVLSTFCSCGQDGLVIFFLTVGMALSGLQYIVNYIDIASTHSGTVMGIGNTMSCMGGIISPMITAAIVEKKTQAEWQIVMMITAAILFAGSLLFCLLAKDEVEPWAKNEEEDAKEVELAPLRNEKD
The following text describes a protein:
Function:
Involved in the synthesis of both tocopherols and tocotrienols (vitamin E), which presumably protect photosynthetic complexes from oxidative stress. Catalyzes the conversion of 2-methyl-6-phytyl-1,4-hydroquinone and 2,3-dimethyl-5-phytyl-1,4-hydroquinone (DMPQ) to delta- and gamma-tocopherol respectively. Also converts 2,3-dimethyl-5-geranylgeranyl-1,4-hydroquinone (DMGQ) to gamma-tocotrienol.
Subcellular Localization:
Plastid, chloroplast, plastoglobule.
Sequence:
MEIRSLIVSMNPNLSSFELSRPVSPLTRSLVPFRSTKLVPRSISRVSASISTPNSETDKISVKPVYVPTSPNRELRTPHSGYHFDGTPRKFFEGWYFRVSIPEKRESFCFMYSVENPAFRQSLSPLEVALYGPRFTGVGAQILGANDKYLCQYEQDSHNFWGDRHELVLGNTFSAVPGAKAPNKEVPPEEFNRRVSEGFQATPFWHQGHICDDGRTDYAETVKSARWEYSTRPVYGWGDVGAKQKSTAGWPAAFPVFEPHWQICMAGGLSTGWIEWGGERFEFRDAPSYSEKNWGGGFPRKWFWVQCNVFEGATGEVALTAGGGLRQLPGLTETYENAALVCVHYDGKMYEFVPWNGVVRWEMSPWGYWYITAENENHVVELEARTNEAGTPLRAPTTEVGLATACRDSCYGELKLQIWERLYDGSKGKVILETKSSMAAVEIGGGPWFGTWKGDTSNTPELLKQALQVPLDLESALGLVPFFKPPGL
The following text describes a protein:
Function:
Lipid transporter that specifically mediates export of sphingosine-1-phosphate (sphing-4-enine 1-phosphate, S1P) and sphinganine-1-phosphate.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.
Sequence:
MCLESDGVGTVSNSQGCIPGAEERGLETLPGRMNPTSLDVKAVELESSSSKPDKAYNWKRASVAAAGILSVGNVLNYLDRYTVAGVLLDIQQHFEVKDSGAGLLQTVFICSFMVAAPIFGYLGDRFNRKVILSSGIFFWSAITFSSSFIPKKYFWLLVLSRGLVGIGEASYSTIAPTIIGDLFTKNTRTLMLSVFYFAIPLGSGLGYITGSSVKQVAGDWRWALRVSPVLGVITGTLLLIFVPTAKRGHAEQLKGSSWIRDMRGLIKNRSYVFSSLATSTVSFATGALGMWIPLYLYRAQVVQKSVEPCNIPPCSTKDSLIFGAITCLTGFLGVIIGAGATKWCRRKTQRADPLVCAVGMLGSAIFICLVFVAAKSSIIAAYICIFAGETLLFSNWAITADMLMYVVIPTRRATAVALQSFTSHLLGDAGSPYLIGFISDLIQQSTTKSSLWEFLSLGYALMLCPFVVVLGGMFFLATALFFLEDREKAEKLEPCSDPFTVGNCSDSEEASIL
The following text describes a protein:
Function:
6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MTLQGNWKKFCLLLTFCALTFLISVLYLCSNSSCDIATLAPNKLRYLSEGNPQKMHRIRFGFTIKESIKKYQFDFAGTDVMVFLHIQKTGGTTFGKHLVTNLQIRKPCDCSKKKGKKFRCTCNRPNSKKIWLFARYALGWPCGLHADYTELTECVPKFINKRDGREKRRFLYVTMLREPMARVISEFLCYTRGTTWAESKHKCKGKVPTKEELPPCYTGDNWMDVTLEGFNKCSSNLAFNRQARMLADLKLVNCYNRTNGPSPRKRGKIILKSAMKNLRNMAYFGLAEYQKESQYLFEKTFGIKFMKPFQQKAEEETRSADAMKSMTQIEKRRTKSLNSLDIRLYDYAKALFFYRVRYFQKEEKRGEKQIFNSS