lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Essential for the invasion of host erythrocytes by blood stage merozoites. As part of the PfRH5 adhesion complex, facilitates the interaction of RH5 and human BSG required for the Ca(2+) release into the erythrocyte.
Subcellular Localization:
Secreted. Cytoplasmic vesicle, secretory vesicle, microneme lumen. Cell membrane; Peripheral membrane protein; Extracellular side. Host cell membrane. Note=In late schizonts, colocalizes with CyRPA in the microneme lumen. During merozoite invasion of host erythrocytes, secreted at the merozoite apical surface where it colocalizes with CyPRA and RH5 at the interface between the merozoite and the erythrocyte.
Sequence:
MFRIFFTLLIIILIKKTSAIDLIEGIFYEKNEIDKLTFSLDHRVRDNLKTDLILNNNGENDYAYLNKYVYTILNRDSTEKIKTFFSHNKDMKSCDYFISKEYNSSDKTNQICYKKTFCGVVIPNSEEIKTNKITNDKLYCAHFNSTHIIIYYISQPLLLEPHVVYEETFFEKGKNDQINCQGMYISLRSVHVHTHNAILQQETLTYIKNLCDGKNNCKFDFDSIKYENKSLTHYLFFINIQYQCISPLNLQENEMCDVYNDDTHKATCKYGFNKIELLKNVCEENYRCTQDICSVNQFCDGENETCTCKTSLLPSAKNNCEYNDLCTVLNCPENSTCEQIGNGKKAECKCENGKYYHNNKCYTKNDLELAIKIEPHKKEKFYKNNLYQGKALKPEYIFMQCENGFSIEVINAYVSCYRVSFNLNKLKYVTESLKKMCDGKTKCAYGNTIDPIDDLNHHNICNNFNTIFKYDYLCVFNNQNITSDKNSHLHSNIPSLYNSSILPDINKSKFHLISRNSRTNQYPHNNISMLEIQNEISSHNSNQFSTDPHTNSNNINNMNIKKVEIFRSRFSSKLQCQGGKINIDKAILKGGEGCNDLLLTNSLKSYCNDLSECDIGLIYHFDTYCINDQYLFVSYSCSNLCNKCHNNSTCYGNRFNYDCFCDNPYISKYGNKLCERPNDCESVLCSQNQVCQILPNDKLICQCEEGYKNVKGKCVPDNKCDLSCPSNKVCVIENGKQTCKCSERFVLENGVCICANDYKMEDGINCIAKNKCKRKEYENICTNPNEMCAYNEETDIVKCECKEHYYRSSRGECILNDYCKDINCKENEECSIVNFKPECVCKENLKKNNKGECIYENSCLINEGNCPKDSKCIYREYKPHECVCNKQGHVAVNGKCVLEDKCVHNKKCSENSICVNVMNKEPICVCTYNYYKKDGVCLIQNPCLKDNGGCSRNSECTFKYSKINCTCKENYKNKDDSCVPNTNEYDESFTFQYNDDASIILGACGMIEFSYIYNQIIWKINNSKESYVFYYDYPTAGNIEVQIKNEIFHTIIYLKKKIGNSVIYDDFQVDHQTCIYENVFYYSNQN
The following text describes a protein:
Function:
Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
Sequence:
MVLVVAGFDPSGGAGIIQDVKVLSALGVKTHAVISALTVQNENRVFSVNFRDWEEMRKEIEVLTPPRVIKVGLSAPETVKRLREMFPDSAIVWNVVLESSSGFGFQDPEEVKKFVEYADYVILNSEEAKKLGEYNNFIVTGGHEKGNTVKVKYRDFVFEIPRVPGEFHGTGCAFSSAVSGFLAMSYPVEEAIRSAMELLKKILERSSGVVETEKLLRDWYRYDTLNTLDEILPEFLEIGHLTVPEVGQNVSYALPWAKNEFEVGKFPGRIRLKEGKAVAVSCASFKDRSHTARMAVTMMRYHPHMRCVVNVRYEREYVERAKKRGLKVFHYDRSKEPKEVQEKEGQSMVWMIEQAIAELKSPPDVIYDEGWWGKEAMIRVFGRNPKEVLEKIKLMVRE
The following text describes a protein:
Function:
Plays a role in microtubule organization. Required for centriole subdistal appendage assembly.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle.
Sequence:
MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVRGEMRVPEEALKHEKFTIQLQLSQKSSESELSKSACAKSIDSKVADSATEVQHKPTEALKSEEKVVDTSAMPRGTPLYGQPSWWGDDEADEQRPFKSNGKPEEKNHETGTSGCSIDAKQVEEQSAAASEEVLFPFCREPSYFEIPTKEFQQPSQITESTIHEIPTKDTPSSHTTGAGHASFTIEFDDSTPGKVTIRDHVTKFTSDQRHKSKKSSPGTQDLPGIQTGMMAPENKVADWLAQNNPPQMVWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEQKKLQKAQATEKHQDQAVTSSAHHRGGHGVPHGKLLKQKSEEPSVSIPFLQTALLRSSGSLGHRPSQEMDKMLKNQATSAASEKDNDDDQSDKGTYTIELENPNSEEVEARKMIDKVFGVDDNQDYNRPIINEKHKDLVKDWALSSAAVVMEERKPLSTPGFHNSEEGTSSSGNKRWVSQWASLAANHTRHDQEERIMELSVPVPLEHDTDISESGISLRSTGSAASLASQGERRRRTLPQLPSEEKSLESSRAKVLAQRSEIGEKQDTELQEKEAPAQVYQKDKQDTDRALSKINRAVNGETLKNGGDSKTLLHLGSSYSGKEKSETDKETSLVKQTLAKIQQQEQKEQAQWTPTKLSSSKNIAGQIDRCREESFKQESQPQEKIPGLSAGKGERAVQNEGKRRKAEEILKSQTSKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQPSSTPPSLALTTASRIRERSDSMDTDSSMDTTLILKDTEAVMAFLEAKLREDTKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVAKSSSSGAREKIEKKTKSRSADIGSRAEGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDVMSSDQETYSCKSHGRTPFTSTDEHAHSKLEGSKVTKSKTSPGAPGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSPSVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSSGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNCRSSDPRPQPAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDEIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAILPSPPKQKSSPVNDHSSPGQTPTLCQPEARVLHPAAGAVSAEFENAESEADFSIHFNRFNPDGEEEDVTVQE
The following text describes a protein:
Function:
Catalyzes the hydrolysis of triacylglycerol. It also exhibits some esterase activity with p-nitrophenyl acetate and Tween 80 as substrates, however the lipase activity is approximately eight times the esterase activity. It shows a marked specificity for the 1,3-oleyl residues of triolein.
Subcellular Localization:
Secreted. Note=During early stationary growth phase about 10% of the enzyme molecules remain cell-bound while about 90% are released into the growth medium.
Sequence:
MKKKSLLPLGLAIGLASLAASPLIQASTYTQTKYPIVLAHGMLGFDNILGVDYWFGIPSALRRDGAQVYVTEVSQLDTSEVRGEQLLQQVEEIVALSGQPKVNLIGHSHGGPTIRYVAAVRPDLIASATSVGAPHKGSDTADFLRQIPPGSAGEAVLSGLVNSLGALISFLSSGSTGTQNSLGSLESLNSEGAARFNAKYPQGIPTSACGEGAYKVNGVSYYSWSGSSPLTNFLDPSDAFLGASSLTFKNGTANDGLVGTCSSHLGMVIRDNYRMNHLDEVNQVFGLTSLFETSPVSVYRQHANRLKNASL
The following text describes a protein:
Function:
Required for retention of late Golgi membrane proteins. Component of the retrieval machinery that functions by direct interaction with the cytosolic tails of certain TGN membrane proteins during the sorting/budding process at the prevacuolar compartment. Binds phosphatidylinositol 3-phosphate (PtdIns(P3)) (By similarity).
Subcellular Localization:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Prevacuolar compartment membrane; Peripheral membrane protein; Cytoplasmic side.
Domain:
The PX domain binds phosphatidylinositol 3-phosphate which is necessary for peripheral membrane localization.
Sequence:
MSAYPQDTYFNSNPYQQQPYAYQPPPQPQPQQPPYQQQPYQQQAYQYNAQQPYQTTDPYAYQQSPPQSSTVPPQSPPVQVTHSPFIRTDSSQAVSFTDMARMAGRPQTFDEMYSVPESFLEIEIRNPMTHGIGRKMYTDYEIVCMTNIPAFKLRHSAVRRRYSDFEAFRDILERESTRVNIPPLPGKVFTNRFSDEVIEQRREGLQRFLEIVAGHPLLQTGSKVLCAFLQDPAWDKSQWI
The following text describes a protein:
Function:
Catalyzes the interconversion of ribulose-5-P and ribose-5-P.
Sequence:
MKIAIGCDEMGYELKQTLITRLKEKNIEFTDFGSFENEKVLYPSIAEKVALEVKNNDYDRGILICGTGIGMAITANKIHGIRAAQIHDSYSAERARKSNDAHIMTMGALVIGPSLAVSLLDTWLDSDFSGGRSQAKVDLMEEIDQKNR
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MATAISSIFRPTVNVPGNVGLKQEADVRTLNSVQPADLMAAETVQSFLEVKQKMVRGTLDHHQTTYRSVAESVHLVPEDMIKQVAERGASNLLGTMDRSAAESVHLVPEDMIKQVAERGASNPLRTTDRSAAEGFQSVSEDRIKQEVQSRTLSSLHFTDMCIETALGHTYKQEMESKTSKSSSVPEHIMQKAESWTLHTSPPPEETIQFVEGVLIKQEVDSNAVHYLSPMNEFIPSVIEVLIKEESEAFLTVGEEIHQLPLKTNIKQEPTGESVEEGVPSSLEGEIVDNGQDTVESGMSFNSGGKSHLCSHCGKVFSTTDQPDIYMRIHSGEKLHQCPCCSKRSCQASHPLLHLRSHAGEKPYECSHCKKRFSLKSNLTQHLKTHTEEKPYECSHCKKGFSQKSILDRHILIHTGEKLHECSHCKKGFSLKSNLTQHLKTHTEEKPYECSHCKKGFSRKSYLNQHLLLHTGEKPYECCYCKKGFSQKSLLNRHLLTHTGEKPFECSQCEKRFFGKNTLKRHLRTHTREKPYECCYCTKEFPQKSALNIHLLTHTGEKPYECCYCKKGFSKKSALTHHLRTHTGEKPYECLHCNKRFSRKDALNCHIRRHTGETPYECCHCKKGFPQKSALNSHILTHTGEKPYECSHCKKRFSRKSNLKKHLLLHTGEMPYECSYCKKGFPHKSALNCHILTHTGEKPFECSHCKKGFSRKINLTQHLLLHTGEKPYECSYCKKVFSRKYHLKQHLLLHEGEKTYECCYCKKGFYQKNTLKCHILTHTGEKPYECCYCKKGFPQKSALNRHILTHTGEKKYECSHCKKRFCLKSNLNQHLLLHTGEKPHECSYCEKGFSRKSALNLHLQTHTREKPYECCYCTERFSQRSEHNFHLRTHTGEKTYECSYCKKGFCQKGTFNQHLLLHKEEKPYECCYCKKGFSRKRGLNEHLLLHNGVKPYVCCYCTKGFSYMSSFNRHLRTHTQEKP
The following text describes a protein:
Function:
DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is both required for DNA repair and heterochromatin organization. Promotes DNA end resection of double-strand breaks (DSBs) following DNA damage: probably acts by weakening histone DNA interactions in nucleosomes flanking DSBs. Required for the restoration of heterochromatin organization after replication. Acts at replication sites to facilitate the maintenance of heterochromatin by directing H3 and H4 histones deacetylation, H3 'Lys-9' trimethylation (H3K9me3) and restoration of silencing.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MNLFNLDRFRFEKRSKIEEAPEATPQPSQPGPSSPISLSAEEENAEGEVSRANTPDSDITEKTEDSSVPETPDNERKASISYFKNQRGIQYIDLSSDSEDVISPNCSNTVQEKAFSKDTVIIVSEPSEDEESQGLPTMAHRNDDISELEDLSELEDLKDAKLQTLKELFPQRSDSDLLKLIESTSTMDGAIAAALLMFGDAGGGPRKRKLSSSSEPYEEDEFNDDQSIKKTRLDHGEESNESAESSSNWEKQENIVLKLQKEFPNFDKQELREVLKEHEWMYTEALESLKVFAEDQDMQYASQSEVPNGKEVSSRSQNYPKNATKTKLKQKFSMKAQNGFNKKRKKNVFNPKRVVEDSEYDSGSDVGSSLDEDYSSGEEVMEDGYKGKILHFLQDASIGELTLIPQCSQKKAQKITELRPFNSWETLFTKMSKTNGLSEDLIWHCKTLIQERDVVIRLMNKCEDISNKLTKQVTMLTGNGGGWNIEQPSILNQSLSLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLYQEGNNGPHLIVVPASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYEDYNVIVTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPVQNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFILRRVKEEVLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKKSINNLEKNTEMCNVMMQLRKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYRHINNFQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYLRLDGKTQISERIHLIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLEQDMTTVDEGDEGSMPADIATLLKTSMGL
The following text describes a protein:
Function:
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient; Tetrodotoxin-resistant channel that mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Plays a role in neuropathic pain mechanisms.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDDLTLLGANNFRRFTHESLATIQKRIAAKKESKDILLRDKLRPQLDLQAFQKLPALYGNLPPELIGEPLEDLDPYYNDHKTFMVLNKGKAIFRFTATRALWIFSPFHPIRRLAIKILSGTNETSSSKYVEFTFTGIYTFECLIKILARGFCLNEFTFLRDPWNWLDFSVIMMAYIGAFIDLGNVSVLRMFRVLRALKTISVIPGLKVIVGALIQSIKKLADVMILTVFCLSVFALIGLQLFKGHLRHKCVKNYTEYVGGNPDYGFTSFDTFGWAFLSLFRLMTQDYWERLYQQTLRASGKIYMLFFMLVIFLGSFYLVNLILAVVTMAYEEQSKATIAETEAKERKFREAMEMLKKEQEVCISFCFLSETISVFHILFMLPVLLHFVSCLELEESNQRCPPFLKKLAFRYLVWECCPMWMKIKKKVSIFVMDPFTDLTITLCIVINTLFMALEHYKMTPGFKLMLSIGNKIFTGIFTAEVILKIIAMDPYYYFQQSSNIFDSIVVFISIIELSIPSGKKGTFTVLRTLRLLRVFKLAKSWPTLNTLIKIILNSINALSNLTLVLALIVFIFAVFGMQLFGNSYRLGRCNITSTCKPRWHMEDFFHSFLVIFRILCGEWIETMWGCMVVAEPPLCLFVFLSVMVIGNLVVLNLFIALLLNSFSADNLTQLPEEDRETNNLKIACARIHRGLQGAKQWMLTFCFKAFGYKKKAAQKKIKCDTEKNGLELTKEGLHSNEKYSNGGNEKMGEKYSMNNILDDYIRNPSVFVSVPIAHGESDSDGSEDAADKQDTVIETDPTKQFSIMCTISFVPLLGFTRHYPWCSVNTTKFPGRMCWNLRKTCYQIVEHNWFESFIVFMILLSSGALAFEDIYLTEKPRIKMMLEYADKIFTYIFILEMLLKWVAYGFHKYFTNAWCWLDFLIVDVSLVSLVASLAGKSEIGAMKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIVGVSLFAGKFGKCINMTEANSTINDALIKTMADCRKVNNTRQQRLYWTTVKVNFDNVGSGYLSLLQVATFKGWMDIMYAAVDSVDVSYSFTLLLRLILMSILIDIITERQPQWESNKYMYLYFVIFIIFGSFFTLNLFVGVIIDNFNQQKKKITPNNNNNCLFFLYFGGEDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKYQGFIFDIATHQAFDISIMVLICLNMVTMMVEADEQSAEKTYVLSKINVLFITIFTAECVMKLVALRYYYFTNGWNIFDLVVVIMSIPETKSLEEPPVLMIKFWILITDFSSLGSVLSGIVVSFSPTLFRVIRLVRIGRILRLIRSARGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMANFAHVKMEVGIDDMFNFKTFGNSMLCLFQITTSAGWAELLSPILNTGPPFCDPNPVSQRGDCGNPALGIMFFVTYIIITFLIVVNMYIAVILENFNVATEESTEPLGDDDFEMFYEVWEKFDPLATQFIPYAKLSDFANTLAAPLRIPKPNKLELITMDLPMVSGDRIHCLDILFAFTKRVLGDSGEMDTLKVQMEEKFMAANPSKSSYEPINTTLQRKYEEMAAVTLQRAFRSHLLQRSMKQASFLHRQKTSDGDILEEDAPEKEGLIAHLMNENYITSPDKTRTPSLESIPPSYHSVTGTLGDGAEGETSKALKHEEPRDGHLSPRKDKESNM
The following text describes a protein:
Function:
Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Note=Predominantly cytoplasmic. Localized to the interphase centrosome and mitotic spindle poles.
Sequence:
MAAQSQSSKRAWKLEEFVAHTSSVNCLSLGSKSGRVMVTGGEDNKVNMWAIGKPNVIMSLSGHTSPVECVKFNPTEELVMAGSKSGTLKIWDLDSAKIVRTLTGHKSNIQSLNFHPYGDFVASGSLDTNVKLWDIRRKGCIFTYKGHTDGITAIEFSPDGRWIVSSSADSSARLWDLTAGKILHSFSHNGPVNTIEFHPNEFLLATGSSDRRIKFSEDGSVIFSGLQDVLKVYNWEPIRCYDTVQVGWEKIVDFTVTSNQLIGASFNQANVSVSIIDIEKLNMTGSSGQHMGITQDHTAKVDIARLETSEIPNSEKAPTSQRQSLTDMGEVERLSSPARDSNPKDIPVDPFKTEVGAVGDTKQSKSNEKCEVENLSEKTTDADDLQSCQNNKRVSSAISSEAVSVTLKEKAPEIDLSLFPTEKTDSKIDENKILLELLKDHSVICSVIGNRIQNLNAIHEPWMNGNIKDSIDKAIQIQDTAVLVDLLNILIRNHKLWTLDICAYTLPQVKTLIQDKRECYIRVACQVLRLILKNFGSLIKSTLRSTDFVTGVDITREERLEKCRICYEELSNIKTVISEKAMISGKIGGTFRELQLAFATAID
The following text describes a protein:
Function:
Uridylyltransferase which mediates terminal uridylation of miRNAs, leading to their degradation. Has high specificity for splicing-derived miRNAs (mirtrons) and other miRNA substrates containing a 3'-G terminal nucleotide. Appears to be a major suppressor of mirtron biogenesis.
Subcellular Localization:
Cytoplasm.
Sequence:
MRIEPGDSFWTKKAMFSNAERQYFETVRPRKTSLPGSTAPNIAAPVTKATKKNKTMAEMMPNKLLYMNPLTMEAHFFLQTLNSVNQTTNPPQLDPHLANLLERIMVGIESYLDRNPTYVLPQEMAAPGEGVAFVQPQELQTIKRTFSCSSCSNRIVGTTIAKAVAHLSEQHPKPNPNNQPVQPHPTHQTKQEKKQAQVKARQHITVRLPKKARAMIVGEITNVFKDKYPIADKLKVIPEYDVIEQDLCKLLSPGFPKQPLRVYKFGSRITGIGNRSSDLDLFVDIGNTFHTFEHRASNATVAKLRAMRKFFCDSEDWRLINFIEQARVPIIKTCHLPTGIECDICLNSMGFCNTNLLKYIFESQPLTQYMCIYVKNWLERCKLTEQISTYSITLMVIYFLQLQALLPPIAMLQIEDAANQAVLVGPWVVNFAQKSFSELGLQQLKATVPVIKGFLRNFFAYFAKFDYEHFLVCPYIGQANVEIAKIERMLHARYSAYVSDNPECSIQLKKPMVVQDPIQLNHNVTKAVTKYGLQTFVDYCQQTAELLEEPSTNWRQRYAF
The following text describes a protein:
Function:
Probable methyltransferase.
Sequence:
MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI
The following text describes a protein:
Function:
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
Subcellular Localization:
Cytoplasm.
Sequence:
MSNSSPSISISNVQLQHISHLTNYNSQIKTHTNPLAVNPFFRTFPGFFLTSSDIVLRHNVLDLSGTFPSPNPPLAYHRAGPRNQILFDPVTVRAAIVTCGGLCPGMNTVIRELVVGLWELYGVREIFGIKAGYRGFYSYDPVRLNPKMVDDWHKRGGTVLETSRGGFDLKKIVDAIQDHGFNQLYIIGGDGTMRGAVEIFEELKQRKLYISVVGIPKTVDNDVGIIDRSFGFQTAVEMAQQAINAAHVEAESAVNGIGLVKLMGRSTGHIALHATLSSRDVDCCLIPEIDFYLEGKGGLFEFLEDRLKEMGHAVLVVAEGAGQDIIPRTESQKTEKDESGNPVFLDVGGWLKSELKNWWSRDHPNELFTIKYIDPTYMIRAVPPNATDNSYCTLLAHSAIHGVMAGYTGFVCGPINGNYAYIPVDEVAKAKNKVDTRDHKWSWVRSVSNQPDFIRS
The following text describes a protein:
Function:
Involved in RNA editing. Catalyzes the specific deamination of adenosine-37 in the cytosolic tRNA-Ala. Generates inosine at the position 3'-adjacent to the anticodon tRNA-Ala.
Subcellular Localization:
Nucleus.
Sequence:
MEEDWGKTVSEKVISAYMSLPKKGKPQGREVTVLSAFLVSSPSQDPKVIALGTGTKCVSGSLLSPRGDIVNDSHAEVVARRALIRFFYSEIQRMQLTSGKSNEAKRQRIDSETSSILESADSSCPGEVKYKLKSGCLLHLYISQLPCGYASTSSPLYALKKIPSTQVDDSLLVQASDICSSRHSDVPEIGSNSNKGNGSQVADMVQRKPGRGETTLSVSCSDKIARWNVLGVQGALLYQVLQPVYISTITVGQSLHSPDNFSLADHLRRSLYERILPLSDELLTSFRLNKPLFFVAPVPPSEFQHSETAQATLTCGYSLCWNYSGLHEVILGTTGRKQGTSAKGALYPSTQSSICKQRLLELFLKETHGHKRESSKSKKSYRELKNKATEYYLMSKIFKGKYPFNNWLRKPLNCEDFLIN
The following text describes a protein:
Function:
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MTSTLELKADKMLKVQFVGDDDVLNHILDREGGPKIKKERAQLLVNTQKIIKKPENELEEDDQEVLKDHNYVEVLGQDVQESLKNGSATDGGNKVYPFQNRKHPEKMAKLASELAKTPRKSVSLNMKNDPKITIDIPQCSKGKILPQLFKESFQELLQIINNDKSEFLSTAPRGLRKRLIVPRSHSDSESEYSASNSEDDEGVAQEYEEDTNEDILSQKIQAQNREVSAPVFRETPSKKMKREKTSHLVEKYFEAHSSSKVLTSDRTLQKLKRAKLDQQTLHNLLSKVSPSFSAELKQLNQQHEQLFHKWMLQLHLGFNIVLYGLGSKRDLLERFRTTMLQDCIHIVINGFFPGISVKSVLNSVTEVLDHVGTFRSVLDQLEWITNKFKEDSSLELFLLIHNLDSQMLRGDKSQQIIGQLSSLRNIYLIASIDHLNAPLMWDHAKQSLYNWLWYETTTYSHYTEETSYENSLLVKQSGSLPLSSLIHVLRSLTPNARGIFRLLIKYQLDNQDNPSYTGLCFQDFYQQCREAFLVNSDLTLRAQLTEFRDHKLIRTKKGTDGVEYLLIPVDNGILTDFLENEEEEL
The following text describes a protein:
Function:
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Mitochondrion inner membrane; Multi-pass membrane protein; Matrix side.
Sequence:
MFRRTPFWPKVTRSWTKSSISAATAHFPDAVRADPASSRTGSTSAKESRSWKLGDDTVKAEALPKHLQLAVRKLQLYGDIVRFTRPVGWQLLLIPCYWGSSLAVTRALVWEGADPVVLCAPFIPLHLCVQFLLGAYLMRSVGCIVNDMWDRKFDRMVERTAQRPLACGAISMAEASVILLLHLAVAGVIALNLSPVALQACVAITPVWLMYPFMKRITYAPQFFLGLCFNWGIFVGYAAVLGRVDMAVCLPIYGGAVIWTILYDTIYAYQDRRDDLKCGVKSTAIWIGDRKYILNAMVAPIGASMLISGFLASQSLPYYIGIVLCMYHLHSIVDDVNIYDSWSCAQGFTRNVRLGMYVFLAMCLGNLCWAFASEHEAELDRNTDSAPKSSVLSRFLFLDQETHGPAYTKGSFNWADRFMHPAFVQAESAKLAGATEAPPIPAWMRREYFWQNVSAILLFCGVAEDTVAAWSTFSYEWMDHYNMFSKVSP
The following text describes a protein:
Function:
Has both a phosphomonoesterase and phosphodiesterase activity.
Subcellular Localization:
Secreted. Periplasm. Note=Secreted and to some extent periplasmic. Secretion is hxc-dependent and xcp-independent.
Sequence:
MFKRSLIAASLSVAALVSAQAMAVTGGGASLPAELYKGSADSILPANFSYAVTGSGTGKNAFLTNNSSLFGTTGTVHYAGSDSVLSGSELTTYNSNYNGTYGPLIQIPSVATSVTVPYRKDGNTTLNLTSAQLCDAFSGAKTTWGQLLGTTDSTPIRIVYRTGSSGTTELFTRHLNSICPTRFATNSTFTNARLPAGGTLPSNWVGVAATSTVVSTVKATNGSLGYVSPDAVNINSNAEVSRVNGNLPTQANVSTALGSVAPPANAADRADPSKWVPVFTNPSAGYSIVGYTNFVFGQCYKDASVSTDVRAFINKHYGGTTTNAAVAAHGFIPLTPAWKSAIVSAFYTGTSENLAIGNTNVCNTKGRP
The following text describes a protein:
Function:
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
Sequence:
MKILQQDDFGYWLLTQGSNLYLVNNELPFGIAKDIDLEGLQAMQIGEWKNYPLWLVAEQESDEREYVSLSNLLSLPEDEFHILSRGVEINHFLKTHKFCGKCGHKTQQTQDELAVQCIHCGYQTYPVICPSIIVAVRRGHEILLANHKRHYSPNGGIYTTLAGFVEVGETFEQAVQREVFEETGISIKNLRYFGSQPWAFPNSQMVGFLADYESGEITLQESEIHDAQWFSYDQPLPELPPTGTIARKLIHVTLELCKAEHKCD
The following text describes a protein:
Function:
Plays a role into cellular response to oxidative stress. Decreases cell proliferation (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSQATKRKHVVKEVLGEHMVPSDQQQIVRVLRTPGNNLHEVETAQGQRFLVSMPSKYRKNIWIKRGDFLIVDPIEEGEKVKAEISFVLCKDHVRSLQKDGHWPEAFSQVTEKDNNDRNRQTQPELPAEPQSSGEESSSEDDSDLFVNTNRRQYHESEEESEEEEAA
The following text describes a protein:
Function:
Phosphatase that hydrolyzes imidodiphosphate, 3-phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAVQRVKLALIDLSGTLHVDDQPTVGAVEALKRLRQHGVQVKFVTNTTKESVGSLYDRLRKIGFELQRDEIYGSLGAAAEYVRRNNLNPYYLLTDDARTDMPPNDPERALDSVVVGLAPERFCYEHLNEAFRVLHQRSVKQEVQLVAVHEGRYYKAKDGIALGPGCFVKGLEYSTGVPAVCIGKPNEYFFRSALPDGIDVAECVMIGDDPNDDCLGAMRIGMKGYLVETGKYQPEKYTDEDRPAVSGIFPTFSDVVQHIISSSAEQ
The following text describes a protein:
Function:
May function as histone H3 lysine demethylase and be involved in regulation of gene expression.
Subcellular Localization:
Nucleus.
Sequence:
DYYRSCPRCSYDLCLTCCREIRDGCLQGGVNMYTSHFDRGKAYLHGGESLPLPSGKKSGIRFSSKKRMRKISQWKARENGDIPCPVNKLGGCGHEYLELKCIFANGWLSELKVKAKKLVKVHNLVDRPHHSGQSCSCFKLNGQIDCCSKSLRKAASREGVSDNYLYCPSATDVQHESLEHFKSHWIKGEPVIITNVLDYSSGLSWEPMVMSRAVRDTSYSKGSQKLVVKTVDCLDLCEVKINTYQFFKAYMEGRTHSNSWPVILKLKDWPPSCLFEERLPCHGAEFMNILPYKDYTHPYSGILNIATKLPPDFLKPDLGPKAYIAYGVAEELGRGDSVTKLHCDMSDAVNVLMHTAKVDYSSKQVAEIEKLKRKHAIQDRREFFNPLYARDETFDMNHSKSEEKLRPISSMQSNTLSLNGKDGGALWDIFRREDVPKLGEYLRNHHKEFRHVYCSPVEQVVHPIHDQTFYLNMYHKKKLKEEFGVEPWSFVQQLGEAVLIPAGCPHQVRNLMSCTKIALDFVSPENINECIRLTDEFRTLPRNHRAKKDKLQ
The following text describes a protein:
Function:
Anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) and protein kinase C (PKC).
Subcellular Localization:
Cytoplasm, cytoskeleton. Membrane; Lipid-anchor.
Sequence:
MGAGSSTEQRSPEQPAESDTPSELELSGHGPAAEASGAAGDPADADPATKLPQKNGQLSAVNGVAEQEDVHVQEESQDGQEEEVTVEDVGQRESEDVKEKDRAKEMAASSTVVEDITKDEQEETPEIIEQIPASESNVEEMAQAAESQANDVGFKKVFKFVGFKFTVKKDKNEKSDTVQLLTVKKDEGEGAEASVGAGDHQEPGVETVGESASKESELKQSTEKQEGTLKQAQSSTEIPLQAESGQGTEEEAAKDGEENREKEPTKPLESPTSPVSNETTSSFKKFFTHGWAGWRKKTSFKKPKEDDLETSEKRKEQEAEKVDEEEGEKTEPAPAEEQEPAEGTDQARLSADYEKVELPLEDQVGDLEALSEKCAPLATEVFDEKTEAHQEVVAEVHVSTVEKMTKGQGGAEVEGDVVVEGSGESLPPEKLAETQEVPQEAEPVEELMKTKEVCVSGGDHTQLTDLSPEEKMLPKHPEGIVSEVEMLSSQERIKVQGSPLKKLFSSSGLKKLSGKKQKGKRGGGGGDEEPGEYQHIQTESPESADEQKGESSASSPEEPEEIACLEKGPSEAPQEAEAEEGATSDGEKKREGITPWASFKKMVTPKKRVRRPSESDKEEELDKVKSATLSSTESTASGMQDEVRAVGEEQRSEEPKRRVDTSVSWEALICVGSSKKRARKASSSDDEGGPRTLGGDGHRAEEASKDKEADALPASTQEQDQAHGSSSPEPAGSPSEGEGVSTWESFKRLVTPRKKSKSKLEERAEDSGAEQLASEIEPSREESWVSIKKFIPGRRKKRADGKQEQAAVEDSGPGEINEDDPDVPAVVPLSEYDAVEREKLEAQRAQENVELPQLKGAVYVSEELSKTLVHTVSVAVIDGTRAVTSAEERSPSWISASMTEPLEHAEGVATPPVGEVTEKDITAEATPALAQTLPGGKDAHDDIVTSEVDFTSEAVTAAETTEALRAEELTEASGAEETTDMVSAVSQLSDSPDTTEEATPVQEVEGGMLDTEEQERQTQAVLQAVADKVKEDSQVPATQTLQRAGPKALEKVEEVEEDSEVLATEKEKDVVPEGPVQEAETEHLAQGSETVQATPESLEVPEVTEDVDRATTCQVIKHQQLMEQAVAPESSETLTDSETNGSTPLADSDTPNGTQQDETVDSQDSNAIAAVKQSQVTEEEAAAAQTEGPSTPSSFPAQEEHREKPGRDVLEPTQALAAGAVPILAKAEVGQEGEAGQFDGEKVKDGQCVKELEVPVHTGPNSQKTADLTRDSEVMEVARCQETESNEEQSISPEKREMGTDVEKEETETKTEQASEEHEQETAAPEHEGTHPKPVLTADMPHSERGKALGSLEGSPSLPDQDKADCIEVQVQSSDTPVTQTTEAVKKVEETVATSEMDESLECAGAQSLPAEKLSETGGYGTLQHGEDTVPQGPESQAESIPIIVTPAPESILHSDLQREVSASQKQRSDEDNKPDAGPDAAGKESAAREKILRAEPEILELESKSNKIVQSVIQTAVDQFARTETAPETHASDLQNQVPVMQADSQGAQQMLDKDESDLQVSPQDGTLSAVAQEGLAVSDSSEGMSKASEMITTLAVESASVKESVEKLPLQCKDEKEHAADGPQHQSLAKAEADASGNLTKESPDTNGPKLTEEGDALKEEMNKAQTEEDDLQEPKGDLTES
The following text describes a protein:
Function:
Modulates RecA activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MPAGTITAIRQQTNDAQRVNIFIDGEFAIGISLNTLTRMRLAVGVHLDDHGWQQLVACEEADQAMQKALRQLERRPRSVNEIYRYLQRKGFREAICQQVVARLQELGLLNDADFAERWVANRRTLRYRGERALRAELRQKGIAPELIEDALSGEKDELGEALRAEQAARAVLARYLRHTDWLTFQRRLGGYLLRRGFASDLVRPLLLRLWREAHPADDIDDEEPY