lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May play a role in neurite plasticity by maintaining cytoskeleton stability and regulating synaptic vesicle transport.
Subcellular Localization:
Cytoplasm, cytosol. Nucleus. Cell projection, axon. Cell projection, dendrite. Note=Mainly cytoplasmic.
Sequence:
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWEDSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPERDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDVAVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCAPWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTITLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENRQLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRNVEELIPALDLLCSAIRESYSEPQSKHFSEQLLNLTLSFLNNQIKELFIHTEELDEHLQKGVNILTSYINELRTFMIKFPWKLTDAIDEYDVHENVPKVKESNIWKKLSFEEVIASAILNNKIPEAQTFFRIDSHSAQKLEELIGIGLNLVFDNLKKNNIKEASELLKNMGFDVKGQLLKICFYTTNKNIRDFLVEILKEKNYFSEKEKRTIDFVHQVEKLYLGHFQENMQIQSFPRYWIKEQDFFKHKSVLDSFLKYDCKDEFNKQDHRIVLNWALWWDQLTQESILLPRISPEEYKSYSPEALWRYLTARHDWLNIILWIGEFQTQHSYASLQQNKWPLLTVDVINQNTSCNNYMRNEILDKLARNGVFLASELEDFECFLLRLSRIGGVIQDTLPVQNYKTKEGWDFHSQFILYCLEHSLQHLLYVYLDCYKLSPENCPFLEKKELHEAHPWFEFLVQCRQVASNLTDPKLIFQASLANAQILIPTNQASVSSMLLEGHTLLALATTMYSPGGVSQVVQNEENENCLKKVDPQLLKMALTPYPKLKTALFPQCTPPSVLPSDITIYHLIQSLSPFDPSRLFGWQSANTLAIGDAWSHLPHFSSPDLVNKYAIVERLNFAYYLHNGRPSFAFGTFLVQELIKSKTPKQLIQQVGNEAYVIGLSSFHIPSIGAACVCFLELLGLDSLKLRVDMKVANIILSYKCRNEDAQYSFIRESVAEKLSKLADGEKTTTEELLVLLEEGTWNSIQQQEIKRLSSESSSQWALVVQFCRLHNMKLSISYLRECAKANDWLQFIIHSQLHNYHPAEVKSLIQYFSPVIQDHLRLAFENLPSVPTSKMDSDQVCNKCPQELQGSKQEMTDLFEILLQCSEEPDSWHWLLVEAVKQQAPILSVLASCLQGASAISCLCVWIITSVEDNVATEAMGHIQDSTEDHTWNLEDLSVIWRTLLTRQKSKTLIRGFQLFFKDSPLLLVMEMYELCMFFRNYKEAEAKLLEFQKSLETLNTAATKVHPVIPAMWLEDQVCFLLKLMLQQCKTQYELGKLLQLFVEREHLFSDGPDVKKLCILCQILKDTSIAINHTIITSYSIENLQHECRSILERLQTDGQFALARRVAELAELPVDNLVIKEITQEMQTLKHIEQWSLKQARIDFWKKCHENFKKNSISSKAASSFFSTQAHVACEHPTGWSSMEERHLLLTLAGHWLAQEDVVPLDKLEELEKQIWLCRITQHTLGRNQEETEPRFSRQISTSGELSFDSLASEFSFSKLAALNTSKYLELNSLPSKETCENRLDWKEQESLNFLIGRLLDDGCVHEASRVCRYFHFYNPDVALVLHCRALASGEASMEDLHPEIHALLQSAELLEEEAPDIPLRRVHSTSSLDSQKFVTVPSSNEVVTNLEVLTSKCLHGKNYCRQVLCLYDLAKELGCSYTDVAAQDGEAMLRKILASQQPDRCKRAQAFISTQGLKPDTVAELVAEEVTRELLTSSQGTGHKQMFNPTEESQTFLQLTTLCQDRTLVGMKLLDKISSVPHGELSCTTELLILAHHCFTLTCHMEGIIRVLQAAHMLTDNHLAPSEEYGLVVRLLTGIGRYNEMTYIFDLLHKKHYFEVLMRKKLDPSGTLKTALLDYIKRCRPGDSEKHNMIALCFSMCREIGENHEAAARIQLKLIESQPWEDSLKDGHQLKQLLLKALTLMLDAAESYAKDSCVRQAQHCQRLTKLITLQIHFLNTGQNTMLINLGRHKLMDCILALPRFYQASIVAEAYDFVPDWAEILYQQVILKGDFNYLEEFKQQRLLKSSIFEEISKKYKQHQPTDMVMENLKKLLTYCEDVYLYYKLAYEHKFYEIVNVLLKDPQTGCCLKDMLAG
The following text describes a protein:
Function:
Microtubule-associated formin which regulates both actin and microtubule dynamics. Induces microtubule acetylation and stabilization and actin stress fiber formation. Regulates Golgi ribbon formation. Required for normal cilia assembly. Early in cilia assembly, may assist in the maturation and positioning of the centrosome/basal body, and once cilia assembly has initiated, may also promote cilia elongation by inhibiting disassembly.
Subcellular Localization:
Golgi apparatus. Cell projection, cilium. Note=Associates with microtubules.
Domain:
The FH2 and MBD domains are essential for its function in regulating Golgi ribbon formation.
Sequence:
MHVMNCVSLASDKENGTLATAAAFMTGQTSPSASPPPPPPPPPPPPCPHSGEGFSPSPPPPLPPPLPGGPPIPPPPPPGLPSVSYLNGYSSLGKKKRMRSFFWKTIPEEQVRGKTNIWTLAAKQQHQYQIDKKTIEELFGQQEDTSKASLPKRGGALNSSFRDAREEVTVLDAKRSMNIGIFLKQFKKSPQSIVEDIYQGKSEHYGSETLREILKLLPESEEVKKLKAFNGDVSKLSLADSFLHCLIQVPNYSLRIEAMVLKKEFLPSCSSLFKDIRTLRAATKELMLCEELHSILHLVLQAGNIMNAGGYAGNAVGFKLSSLLKLADTKANKPGMNLLHFVAQEAQKQDAILLNFSEKLQHVQETSRLSLDITEAELHSLFVRTKSLQENIQLDQELCQQMEDFLQFAVEKLAELELWKRELQGEAHTLIDFFCEDKETMKLDECFQIFRDFCTRFNKAVKDNHDREEQERKQLQRQKEMEQKRYSWSTGELGSFGRSSSENDVQMLAKTGTEDLPSFLKPRPNSPSYRPPNTRRSRLSLGISADRELLTFLESATSSPEDPNKFNSLPRSSPRQARPTIAWMEPREQQSHGPNFTHEPQASKIQEKAPPPAWQNQLPTTWREEPASPLPLAGRSRPSLRKRNSEPVGLGPTQSPPLLPLDLGVREHELVTGLTQFDLQSPKSLEEGSQLTLNDFCPTKLPSPGDRSSQPFAAGGDSLPPKDTDTQEVLSPAGEDDRTISDEPSSEALVSVVVTDTEDKDAGPLLYVSDTTDCSLTLDCSEGMDSRAGGDKQEEEKEGDGSVSSGAGEAGSSQVSSNSVSSPPGEVPAPKSSKSELSCQGGLPKDRPSRGKDAIAPKRNSFKEASVGASKPVSARRSQGVTTKPVRTLNSSENEHMRKVVPISKSSRGAGPWKRPEPTPKATPRETPSSTDTPLSRRSSVRGTSDTSPRRPQVSGSGAEEPRLPRSSGSISGRPGKDAPLQPRASFRKPSAKPLRNIPRQKPEENKVSSPNSPDPESPKEEPKAPQATGVSRALPPIPSFARNTVASSSRSLRTDAPPAARTTGLTRTVSQRQLRVKGGSEDSASKDIGTLKRASSARASKKCPESAGGSSANVETSLKGRGTTERSSLRLKDSGQATLGRILRPLQK
The following text describes a protein:
Function:
Involved in spliceosome maturation and the first step of pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MKRKAVLEAFSDSEDEDEKKLKGPQLITGFSAEEGVHYQNETIQRIHEKKRAPKIIHIASDENWMEKRKARFKKKETEVHEKPSQLPDSGLNYGLNIRVASSSAADNEIVDWKANNSNEKAQNKIATNKESTDILPEEVQLVLNDLNDDVKSANSANLQPITTNVVNEKDAYRKDIDELPEPSNMKDYSEIPVEEFGAAMLRGMGWNGQLSSKDAFDVNQRPTFLGMGAKPVDSELTELDIWKNPKKTMFLPVKPLESNSALNSQNEHTEVQKKSNSIDNLTPSSELFRKRSRDNNLSRESSVSSKHLDYNSRNYNKRDRDPDRTKYREYHSERRKQHRTDRYSDDYYQGRSYSYKKRSHRSDRYTERENPDRSYRSTRTL
The following text describes a protein:
Function:
Plays a role in the sorting and targeting of vacuolar proteases.
Subcellular Localization:
Membrane; Single-pass type IV membrane protein.
Sequence:
MSEDEFFGGDNEAVWNGSRFSDSPEFQTLKEEVAAELFEINGQISTLQQFTATLKSFIDRGDVSAKVVERINKRSVAKIEEIGGLIKKVNTSVKKMDAIEEASLDKTQIIAREKLVRDVSYSFQEFQGIQRQFTQVMKQVNERAKESLEASEMANDAALLDEEQRQNSSKSTRIPGSQIVIERDPINNEEFAYQQNLIEQRDQEISNIERGITELNEVFKDLGSVVQQQGVLVDNIEANIYTTSDNTQLASDELRKAMRYQKRTSRWRVYLLIVLLVMLLFIFLIMKL
The following text describes a protein:
Function:
Degrades mitochondrial transit peptides after their cleavage in the intermembrane space or in the matrix, and presequence peptides; clearance of these peptides is required to keep the presequence processing machinery running (By similarity). Preferentially cleaves the N-terminal side of paired basic amino acid residues (By similarity). Also degrades other unstructured peptides (By similarity). May function as an ATP-dependent peptidase as opposed to a metalloendopeptidase (By similarity).
Subcellular Localization:
Mitochondrion intermembrane space. Mitochondrion matrix.
Sequence:
MLKTRLKQSRAISRVVRRYACSHPISPNLDKYPVGLKLHGYEVTQTSPIPEFSLTAVSLKHTESGATHLHLDSPNDSNNVFSIAFKTNPPDNTGVPHILEHTTLCGSKKFPVRDPFFKMTNRSLSNFMNAMTGHDYTFYPFATTNSKDFENLMDVYLSSVFEPQLNHTDFLQEGWRIENQNVHDISSKLEFKGVVYNEMKGQYSNSAYYFYIKFLESIYPSLNNSGGDPKKIVDLSYEGLLEFHSKNYHPSNAKTFTYGKLPLEDSLSKISKYYESFEKKVSSVDVKQPIFSTDKSEIFDVTIPGPVDTMNGKETSEQYCTSITWNLGNPLDPNMQYDIFKWKILSSLLFDGHNSPFYQELIESGYGDDFSANTGLDSTTALLSFTVGLNYLTKQKVDNFNEKVMEIINNKIIPELSNEESSSYHGRIDAILHQIEIGFKRHKPDFGFGLLSSIVPSWVNGVDPIDTLQVEKILSHFKEDYKQNGLRIFKELLEKTLCNPHSQKFKFTMEPREDFTKQLVKDENLMIEKRVSELTEDNKKAIYEQNLELAKLQLEDQNTEVLPTLTIDDIPKRGDFYAIDLGQVNKKVVHERVVDTNGLVYANALKDISYLPTKLYKYLPLFNNCLTNLAGTENTPITELETKIQMLTGGITFSSKISTDPYNIEQLKLQYVLSGMALKEKSSSVYDLWLEILTTTKFDTSDEVLEKLSVLIKNMGQNQINNIADRGHSYAAAVSSSKLTPSKYISDIVSGLSQVQFVMELNSKLESEGKEYLAKEIIPILQEIQKYVLQGEFRYRLVGNQEIIVENEKLIEKFDKDISSNRPTLSLTVTDGLSALLNSFNYNHTSENVLVNLPFQVGYSSLGKIGSSYSSKDGASLQILSQLYSFKNLHSKIRESNGAYGGGLTYDGLNGTLNFYSYRDPNPVKSIQTFRDSLSYGLDANWNDKDLQEAKLRVFQSVDAPINISSQGASAFFENIDDYLRQERRENFLGTTLKDLRDVTEKYLVDNQNNLVTVIGDNEILNVDNKWQIRNFQV
The following text describes a protein:
Function:
Part of the ESX-1 specialized secretion system, which delivers several virulence factors to host cells during infection, including the key virulence factors EsxA (ESAT-6) and EsxB (CFP-10).
Miscellaneous:
MISCELLANEOUS: Was identified as a high-confidence drug target.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MRNPLGLRFSTGHALLASALAPPCIIAFLETRYWWAGIALASLGVIVATVTFYGRRITGWVAAVYAWLRRRRRPPDSSSEPVVGATVKPGDHVAVRWQGEFLVAVIELIPRPFTPTVIVDGQAHTDDMLDTGLVEELLSVHCPDLEADIVSAGYRVGNTAAPDVVSLYQQVIGTDPAPANRRTWIVLRADPERTRKSAQRRDEGVAGLARYLVASATRIADRLASHGVDAVCGRSFDDYDHATDIGFVREKWSMIKGRDAYTAAYAAPGGPDVWWSARADHTITRVRVAPGMAPQSTVLLTTADKPKTPRGFARLFGGQRPALQGQHLVANRHCQLPIGSAGVLVGETVNRCPVYMPFDDVDIALNLGDAQTFTQFVVRAAAAGAMVTVGPQFEEFARLIGAHIGQEVKVAWPNATTYLGPHPGIDRVILRHNVIGTPRHRQLPIRRVSPPEESRYQMALPK
The following text describes a protein:
Function:
In complex with CFAP263, acts as a regulator of ciliary beating that connects radial spoke 3 (RS3) to the inner dynein arm (IDA) and the nexin-dynein regulatory complex (N-DRC). The complex is positioned parallel to N-DRC and forms a connection between the arch at the base of RS3, the IDA tail and N-DRC.
Subcellular Localization:
Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes at cilium but not at the ciliary tips.
Sequence:
MDVSSEHTKDPGGEGGDGESLAARPSKIKASSGPPTSPEPGELESEPEEEEEEQAASQGGTAADEQAEAPKGLTAAEAAGEEGPGEPGRPAEPQPEPEEPAEVGAEEPAQPEPGAGPEELEAEAGAEELEQAAEGKEVRFQASLPLTRIDEEEAAAAPEAETERVEGEEEDKEETQRDGAESKERDGEGRPAKSQEEGKRLYGRDEFEDLEWSEEVQKLQEQQLRSDLLDQYRSLLVERNRSQRYNLYLQHKIFEALRRKKGLEAAEVADRGAEAEAPEKEQAYLRHLGMLEELKKQQADDLQWYHQELGQLKRQCQEKLTRVEKEWRRFQALKKQVVMQAMGSCRMRGGRQAALREVEQIQALEDKKEKEMSAVRLENIQLKQSLVHFETRMRTQEDLTQGLLLIDFEQLKIENQTFNEKIEERNEELLKLRSKVTNSVQVITHVKEKLHFMDMENACKKTQLAEIEAQAALGRDILTKTKQAREGLRTDNIRLNQKCGLLGKDSLLRDLEEKVDKTELLHRRLESLKRHHASLTLSCRGVRQKIREAKAFLPS
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MSVPRARLLQLVKARCELFSTTFNPEGIRTGNKILRQRLKGPALATYYPRKNVGIRELQKEFGTLGLEVDDEVDDDRLEHLAALRARDKGAPKKKRTAPSAADAKKKK
The following text describes a protein:
Function:
Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate.
Subcellular Localization:
Nucleus.
Sequence:
MIQLEEREIPVIPGNKLDEEETKELRLMVAELLGRRNTGFPGSQPVSFERRHLEETLMQKDYFVCEKTDGLRCLLFLINDPDKGEGVFLVTRENDYYFIPNIHFPLSVNETREKPTYHHGTLLDGELVLENRNVSEPVLRYVIFDALAIHGKCIIDRPLPKRLGYITENVMKPFDNFKKHNPDIVNSPEFPFKVGFKTMLTSYHADDVLSKMDKLFHASDGLIYTCAETPYVFGTDQTLLKWKPAEENTVDFQLEFVFNEVQDPDLDERDPTSTYLDYDAKPNLIKLRVWQGSNVHTDFAKLDLSDDDWERLKALEQPLQGRIAECRQSTTKKGYWEMLRFRNDKSNGNHISVVEKILVSIKDGVKEKEVIEWCPKISRAWKKRENDRRQKHFNGVARPASVSHEEPLRKKIKTESNGNGHQTPPRQEQQQQSQQILNDIPTYEDSDDE
The following text describes a protein:
Function:
Forms chloride channels.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane.
Sequence:
MMHYERSKSQVFQVPSALAVANTAPDANRFGECICILMRWKGSIYKLVWRNLLVYYTLYYMLTILHKFILDEDGQKTFTALAKYCSRNENSFNFMIMLGFFTSTAMQRLFAMQTMMPGTAKVIGCFTLAIKPNMPEIYPDMFSLQTAGILRDKERLILERADADDRMLLLLKETSNQNRFVEKSSHLKLVEAVLAFKKSCGNTIKAAIIIVYAFGLLTLMARNLDEDNEEENKLANNIVSYFPILPSMQFFIFLAWLKFGRAAVNPFGTDETDIDIKHLLKTHIQDSLRLTKLYTQNLEDFFGMMLESWPAARPCSTGVYNFLYLPYGCVVAQEQLQSCSQLFQFGSASDADASLTVSMR
The following text describes a protein:
Function:
Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of wapl which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair (Probable).
Subcellular Localization:
Nucleus. Chromosome. Cytoplasm. Note=Associates with nuclear chromatin from S phase until metaphase and is released in the cytoplasm upon nuclear envelope breakdown.
Domain:
The KEN box is required for the association with the APC/C complex.
Sequence:
MSEGKKRSRGGLAIISPPKRRSQRKSTSDSPIPEPIMKRSITVKKIMPRKTLAAIVNTGSQSTPKVSNVPPAPRRSSRISPKIQKENAFSEQSQIVHKDVPGQSSAPKINVLSPIPVNIQLSPKQDNRDIIMSQKVRRSYSRLEMSLNSSSSLYSPTRKTDSSDTSTPNVVLKSGRSSLFGFDKLLNSEMPDGELKKSNGVTRKKNTKERILGTVLPEQPDHNIPGVVLAKQKRRKRKVAIIEKSDLDEWAAFMNAEFEEAEKFDLTVE
The following text describes a protein:
Function:
This is a 2S seed storage protein.
Sequence:
MAKLILVFATLALFILLANASIYRTVVEFEEDDDVSNPQQGKCQREFMKHQQLRGCKQWIRKRAQQGRIGYEADDFELTLDVDLEDDENPMGPQQQSSLKMCCNELRQVDKMCVCPTLKKAAQQVRFQGMHGQQQVQHVFQTAKNLPNVCKIPTVGSCQFKASPY
The following text describes a protein:
Function:
Transcription factor. Efficient DNA binding requires dimerization with another bHLH protein, such as ARNT homolog aha-1. Regulates transcription of target genes, probably acting in complex with aha-1.
Subcellular Localization:
Nucleus.
Sequence:
MSTTVPLHASSFSSGTTGAGGGVQQALQLQHCAYHVGASVGSSGSALNNNSINVPNNNTMGMSSAGSSNGSNLVNGQQRSTRGASKQRRDQINVEIQKLRDLLPLSDLIKDRLFQLQVMSLGCIFIRKHRYQQTVLQPQLQMLQMQMSSPMPRGIDICKALRGFMLMVTRSGKILHVSDNASEYLGHSVEEIMCQGDSIYDLVDGRDHGAVQAELASGPPGAATFPEERVFICRLNLARTAKRQLQYHKFVLFQGRYIQPAEFYQQLNAQNSQPDCDQPVFSAYCQPLINPENAEGMSTGNTHVFSTQHYLDMKFKEADTMASQHLGFSKEQLKGMSWYGMIHPNHVPEIAHKHRLLCQEKEGSVLALIRLQAANGEWIWLHTVFSIRPNNELNSDGKRLRHVIHCFHQKLTDLEAATLQANSWIYSMRHTYPTVFSCQDSPPPSEEQQPSSPQTPPFTEQPPMLVEQKPLIGAGIAPGFPSLDYNQIKVEIPMRPINTQIPLFTPESSSPESSASLHTSLLPHHNAFPLDILEDILPSNDVLPELKDEVDEILRQVEQSPATSPAHSFPSNVNFGHRHSMPNAFDSAELYKYLGPALFDGNFAMQHQHHLQQQHQSQPNHPLQMTPIPPMSCPPSNYGQSNFLFHHQHLNQHLHHSQPPHPYHFDYYNRKRSWAV
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MLLIPAAGRETMSDRASFLRGSLIESQTNTQGVVTILGSFDDRLSHLDAVMRPTQERTFGIRLAHENIDRTLRSADRILLHFDKCRKAENRIQRGLHEDIEGFMDAVNQLRSSSNFFRDNLKYESNTAMFTQVNTILSKAISKLELEFKTLLMSNSKLLDVQLLYESLPPRRSSKQSGSDLQVYELPTLISPRILPLLYQLVQQLAQSGRQIQCSKIYQDARSLKLEKCVQKFGLGNDKFTVDTVQEMQGSSLKERITDWTKCTRVTVLLLFAAERKLYDKIFQGIGKLNEEIFAEVTSASLRMIVNFVEVIVKCPHGPENLFIIFEMFDVIHELQSDIEITLKGNACAEKRTSFLMLRKQIAFTIQGILGKFPESIEKDPSKGVPSNGKVHPVNSYVMNYLKLLLDFLPSIRVFYKDFVIEDASNPETLVLNIMQALLTNLELKSKQYKDPALAHIFLMNNYHYIVLAVKDSKAKDLLGDDWVQKQRRIVQQNALMYKRESWKKILNALSIQTPGGTSEVSSGVSKEAVKDRFKSFNSQFEEIHQRQSEWIITHSELRESVRLSVNEILQPAYRSFLKRYRPVVERSRNLDKIIKYNPVTLDKMLGDFFEGKSVYVSKR
The following text describes a protein:
Function:
Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump.
Miscellaneous:
MISCELLANEOUS: Deletion of the arsB gene results in both an aresenite- and arsenate-sensitive phenotype in the absence of IPTG.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKRLSFLDRYLTIWIFLAMALGIGLGFIFPSFVGGLNKLQVGTTSIPLAIGLVLMMYPPLAKVRYEEIGRVFKDIKVLILSLVQNWIIGPTLMFILAIIFLPDKPEYMIGLIMIGLARCIAMVIVWNDLSKGDTEYAAGLVAFNSIFQMLFFSVYAYIFVTVIPQWLGMEGAVVNITMAEVAKSVFIYLGVPFIAGMVTRYIFVKVKGKEWYEKVFIPKISPITLIALLFTIIVMFSLKGDVIVSLPLDVVRVAIPLLIYFVLMFFVSFFLGKKIGANYAVTTTLAFTAGSNNFELAIAVAVGVFGIHSGAAFAAVIGPLVEVPVMIALVKVALWFQRKYFGSHSM
The following text describes a protein:
Function:
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
Subcellular Localization:
Cytoplasm.
Sequence:
MSDALPATFDVIVHPARELRGELRAQPSKNYTTRYLLAAALAEGETRVVGVATSEDAEAMLRCLRDWGAGVELVGDDAVIRGFGARPQAGVTLNPGNAGAVARFLMGVAALTSGTTFVTDYPDSLGKRPQGDLLEALERLGAWVSSNDGRLPISVSGPVRGGTVEVSAERSSQYASALMFLGPLLPDGLELRLTGDIKSHAPLRQTLDTLSDFGVRATASDDLRRISIPGGQKYRPGRVLVPGDYPGSAAILTAAALLPGEVRLSNLREHDLQGEKEAVNVLREMGADIVREGDTLTVRGGRPLHAVTRDGDSFTDAVQALTAAAAFAEGDTTWENVATLRLKECDRISDTRAELERLGLRARETADSLSVTGSAHLAGGITADGHGDHRMIMLLTLLGLRADAPLRITGAHHIRKSYPQFFAHLEALGARFEYAEATA
The following text describes a protein:
Function:
Probable transcriptional activator that binds to the DNA sequence 5'-[AG]CCGAC-3' of the cis-acting dehydration-responsive element (DRE).
Subcellular Localization:
Nucleus.
Sequence:
MAAGEGDVGMEVETKAPAMPPPPPASSSAARKKKQARAKNGDTPEPDAAGGARARASRRAKRGPGSYRGVRQRRWGKWVSEIREPNRGKRHWLGTFGSAVDAALAYDKAAASILGPRAVLNFPAFSPPAAAIAAPEQCEPPFCSPATTAAATAPEQRQTPGCSPAAVAGSGGGAVFEERDVKPVVLPLPLPAILQDGGGTEAMAQHWDWEWDASWPELEMFECLDDIAMYLDVDAVMTTRDCKVEELDADIVDSPLWTLSD
The following text describes a protein:
Function:
Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation.
Subcellular Localization:
Nucleus.
Sequence:
MASMVPQMVQPQPLPTLPASWQSEADTADRQRMTDHIYHIFQSKRPSQQPYNNKLPEFVKRLEDGLYRSAKSKDEYTDMNTLEQRLHDVAKRFVARPNAGQQPPQPGAPPGGVLQGTQMAQNGLQQPVAPPGQMPGMMNVPMQNMAQFQNGMQQPMQAQQGFMPNNGAMTANMGLQDPLRNQMAQVPGQNMVATQPMQQLDPANQYPLMGANNTAFNAGAPMPQGVMSNGAPVLIRGQRDWNAQPTQPMLGAQPAPQPMNKLTINGLLPGQLATGPGMVPQQQQMPQQGFVPSAAAAPAPSGMIPMGNGMVPMGAPAMPMGNNGSPMLNGMGMFNAPQQTVPNGGMAAVGPSLPGMVPVGGMANNPASLPGMMPVANNAAFPGPGGVNPMGQVPAMPAPIPNGGLPGMNAAGGADDPAKQREQSIQKQQRWLLFLRHCAKCRAPGEDCQLKSQCKFGKQLWQHILSCQNPACEYPRCTNSKDLLKHHQKCQEQTCPVCMPVKDYVKKTRQATQQQQQMQQQQQIQQQQQQQMQQQQMQQQQLQQQQMQQQQQMQQQQQPGVGANFMPTPPMMPNGMFPQQQPQQAMRLNANGLGGQKRPHEMMGMSSGGMDGMNQMVPVGGGGMGMSMPMGMNNPMQGGMPLQPPPQVQAPGQGPMMSAPQQQQQQPAPKRAKTDDVLRQNTGTSLLETFDAKQIRVHVDLIRAAAVTQKAQQPPPANPDDACKVCALTKLSFEPPVIYCSSCGLRIKRGQIFYSTPPDHGNDLKGYFCHQCFTDQKGERILVEGVSIKKSDLVKRKNDEEIEEGWVQCDHCEGWVHQICGMFNKGRNNTDVHYLCPDCLAVGYERGQRQKTEVRPQAMLEAKDLPTSRLSEFITERLNRELEKEHHKRAEQQGKPLHEVAKPEPLTVRMINSVMKKCEVKPRFHETFGPTDGYPGEFGYRQKVLLLFQSLDGVDVCLFCMYVQEYGKDCPAPNTNVVYLSYLDSVKYFRPEIPSALGPAVSLRTFVYHQLLIAYVEFTRNMGFEQMYIWACPPMQGDDYILYCHPTKQKTPRSDRLRMWYIEMLKLAKEEGIVKHLSTLWDTYFEGGRDHRMERCSVTYIPYMEGDYWPGEAENQLMAINDAAKGKPGTKGAGSAPSRKAGAKGKRYGGGPATADEQLMARLGEILGGNMREDFIVVHMQVPCTFCRAHIRGPNVVYRYRTPPGATPPKAAPERKFEGIKLEGGGPSVPVGTVSSLTICEACFRDEETRTLTGQQLRLPAGVSTAELAMEKLEEMIQWDRDPDGDMESEFFETRQTFLSLCQGNHYQFDTLRRAKHSSMMVLYHLHNPHSPAFASSCNQCNAEIEPGSGFRCTVCPDFDMCASCKVNVGHAHPVVPHKRALDETRQRLTEAERRERNEQLQKTLALLVHACGCHNSACGSNSCRKVKQLFQHAVHCQSKVTGGCQLCKKMWCLLNLHAKSCTRADCPVPRCKELKELRRRQTNRQEEKRRAAYAAMLRNQMAGSQAPRPM
The following text describes a protein:
Function:
Part of a heterodimeric complex that catalyzes the two-step biosynthesis of 4-amino-4-deoxychorismate (ADC), a precursor of p-aminobenzoate (PABA) and tetrahydrofolate. In the first step, a glutamine amidotransferase (PabA) generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC. PabA converts glutamine into glutamate only in the presence of stoichiometric amounts of PabB (By similarity).
Sequence:
MTSVLMIDNCDSFTYNLVDQFSPHGTIVIVKRNHPFYDGEIEAIMALTSICITPGPCYPAEAALNSCSIIGHLAGRIPILGICLGQQALGQARGGLVIFAHGKLSNIEHNGIFAPLFNPPRALPAGRYHSLVVEPARIEVTGQCNQLEVVPQEIMAIRHRDLPVEGVQFHPESILSSNGAAILANLIHRPCH
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Sequence:
MQILRLSGRHLCNITLKCLKRQITTLSVPDRSVSDITSSIFEVTKDINHGPRSSTKVMKYVSSFYQNVKIMNLEQISRILTDIANDMLKRDDNVINNCEFYFNCLKIGLNCFSESTSTEALYLLRNNIEDYRKVIVKFRGLGTVPETVPYSEMKNIQNLFLKTILHLYSVSKQSGKSRIITNPIMEYFLHSLKSFDTDIQEFANELTQEESLQKALTEICFEKQISLPVTKTSIEREPYHSVSIDQYLDEYGGIDYENICKYISDYKFTWRGQYINDKLFNYYDTLSTEEKSQFMEAYLDFNKSKELIIEKYTNRIVHVSSEASKQFEKSFKFGMSEKNLIHKWITDTTEQIEKILEIETSLSNEEVIIHHFKPFLETVTIQSIINYIIFSILGSPDGKLTTVIEKMKYSFPSVLSQHASPNLKGEVFQYINDDAYIKLTHQLVKLIIENCKVPITSKQMEQLQNSLKLENKEIADQFLISSGGNDDEYLAFCKETKRITNTKNKTYIIVKMHPYIELKLQSLKLGTHLHYLPMLHPPKPWVNPQSGGYLTIKTSFVSTNDSIQVELLNRAGVRGQLDNAYSCLDQMGNTAWAINPLMLDVFNKLMGNPDGFLSIPPSVPDETLPQKTKTELKSLRITFEIMNKLANAFGENGDLLYHCYSLDFRGRIYPFSPLTHYGGDLARSLFMFWYSEPLGPNGFYWIKYQLASLFGQKNCLEFYEENYDNIIDSARNPMTGKKWWMKADKPFSALAVCFEIKKILDYRMSGGKIEDYKCRLPIHQDGSCNGLQHYAGLAADETGGAAVNLIRSETKQDVYTKVLEIVKKKIEQDISEQNLGTVNLETAKFFLPILNRKLVKRPVMTTVYGVTLAGASSQIMQTIKEIVEDHRTNPSKTTFSNETLHKLKSVQLTQTSYLAKKILDSIDELFVHAKQIEKWLLQNTKRILTSYNIKTIDHLLNNNPSSFETIFTTPMSFFPMSWISPCGLPVIQAYRKIPTSRFNGAIGKTTWNNSNKLSPMDRRKHELGIAPNFIHSLDAAHLFMTCDSANKAGLTFSAIHDSYWTHPNNVEKLSKILREQFVELYSMDYLKYVRQDFINQVKNSYQLVYFKKKDYPGLANKIAEIRKHYPERKKPHKLAFELREMTEQGEEHIMRKLYQRYKPRVFHIVSDKCYEYRNDTVVQPEPKCKGMMEIFVPVSIINVPPKGNLDISKVLDSPYFFS
The following text describes a protein:
Function:
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MPLLRGRCPARRHYRRLALLGLQPAPRFAHSGPPRQRPLSAAEMAVGLVVFFTTFLTPAAYVLGNLKQFRRN
The following text describes a protein:
Function:
Septins are GTPases involved in cytokinesis that assemble early in the cell cycle as a patch at the incipient bud site and form a ring before bud emergence, which transforms into an hour-glass shaped collar of cortical filaments that spans both sides of the mother-bud neck. This collar persists until just before cytokinesis, when it splits into two rings that occupy opposite sides of the neck. The septins at the bud neck serve as a structural scaffold that recruits different components involved in diverse processes at specific stages during the cell cycle. Many proteins bind asymmetrically to the septin collar. The septin assembly is regulated by protein kinase GIN4. Septins are also involved in cell morphogenesis, chlamydospores morphogenesis, bud site selection, chitin deposition, cell cycle regulation, cell compartmentalization and spore wall formation. SEP7 is required to convert hyphal septin rings into the hyphal-specific state and is necessary for CDC10 turnover during hyphal growth.
Subcellular Localization:
Bud neck. Note=Present at the bud neck during cell division.
Sequence:
MSRFDYRNTSKNTSVVDPDHSSPIINYRKDAKKGIKFTFMVVGESGTGKTTFINSLLNKKVLNHRYEKLSPTVGDTKTLMFTSAKSVALPNTSILTKNEFNPRTINEEPGIALTETHIEIIDDDNQKLLLNIIDTPGFGENLNNELCFIEIENYLKQQFDLVLAEETRIKRNPRFVDTRVHVMLYFITPTGHGLREIDIQCMKRLSKYVNIIPVIGKADSFTLNELQHFKQQIRIDIQKFNVPTFQFDNSLNDYDEDEDYDLIQECKFLTNLQPFAVVTSEDVFEVRESTTSTKGNNDKPKIIRARKYPWGLVDINDTRYSDFPILKSVLLGSHLQDLKDLTHDFLYETYRTERLTKVTGNGQAFDDEENEDAEFHDTVEHQLNDSNRGVGGDDNNNNNNNNNNASTIPSMSNLAQLTTSTNEHDASHIDNNSITSTSSSIKKSTSMLIDDHPSSSPKLKNISSFTSSTSTVSLEGGEKEGGHHDRGANSTSTNNNNNNNAFKRLSIGPQRNQLRQISETVPYVLRHERILERQQKLEEMEQASARELANRAALLEKKAAQLKAKEKALRQLELNRQKQEESATSSLHRKDSDISGSVQSGGVDDGKSESTNNNNNNRNGYGYGHGHGHGQSHEYDNSEYHHDDSTPNYETSRLQKDETLTDLHSIVSNH