lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in the export of the long day-specific flower-promoting signal (florigen) RFT1 from the phloem companion cells to sieve elements. Promotes flowering under long days through the transport of RFT1 from the leaves to the shoot apical meristem (SAM).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MTMTGGHHHDAHHEDFQLKDTNPLLGEQWPKGAAGPARPAVGGGIAGWLGLEKPSSTYDLVEQMFFLYVRVVKAKDLPPNPITGSPMDPYVEVKLGNYKGTTKHYDRRANPEWDQVFAFSKSRVQSNVLEVYLKDKEMLGRDDYVGRVVFDLAEVPTRVPPDSPLAPQWYRLEERRVGGGGDGGGLKVRGELMLAVWIGTQADEAFPEAWHSDAATVRGEGVASVRSKAYVSPKLWYLRVNVIEAQDVQPQARGRAPEVFVKAQVGNQILKTSVVAAPTLNPRWNEDLVFVVAEPFEEQLLLTVEDRVTPRKDDLLGRAALPLALFEKRLDHRPFVQSRWFDLEKFGIGGAIEGETRRELRFASRVHVRACLEGAYHVMDESTMYISDTRPTARQLWKPPVGVLEVGILGAAGLQPMKNRDGRGTTDAYCVAKYGQKWVRTRTMLGTFSPTWNEQYTWEVFDPCTVITIGVFDNNHLGNGNGNGNNAGGGGGGSPPARDARVGKIRIRLSTLETDRVYTHAYPLIVLQPSGVKKMGELRLAVRFTCLSLMNMVHLYTQPLLPRMHYLHPFTVTQLDALRYQAMGIVAARLGRAEPPLRREVVEYMLDVESHMWSMRRSKANFFRAVSLFSGAAAAARWFADVCHWKNVATTALVHVLLLILVWYPELILPTVFLYMFMIGLWNYRRRPRHPPHMDTKMSWAEAVHPDELDEEFDTFPTSRQQDVVYMRYDRLRSVAGRIQTVVGDMATQGERLQSLLGWRDPRATCLFVVFCLVAAVVLYVTPFRVVALVAGLYLLRHPRFRSRLPAVPSNFFRRLPSRADSML
The following text describes a protein:
Function:
Cortical microtubule plus-end tracking protein required for cell morphogenesis and cell division. Promotes the stabilization of dynamic microtubules during mitosis. Regulates microtubule-cortex attachment, thereby contributing to self-organization of cortical microtubules and subsequent cell shape.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, phragmoplast. Cytoplasm, cell cortex. Note=Associates with cortical microtubules.
Sequence:
MEEALEMARAKDTKERMAAVERLHQLLEASRKSLSPAEVTSLVDSCLDLLKDSNFRVSQGALQALASAAVLAGEHLKLHLNALVPAVVERLGDSKQPVRDAARRLLTTLMEVSSPTIIVERAGSYAWMHKSWRVREEFARTVTSAIGLFASTELPLQRVILAPILQMLNDPNQAVREAAILCIEEMYMQGGSQFREELQRHHLPSYMVKDINARLERIEPQLRSTDGRSAHHVVNEVKASSVNPKKSSPRAKAPTRENSLFGGDADITEKPIEPIKVYSEKELIREFEKIAATLVPEKDWSMRISAMRRVEGLVAGGATDYSCFRGLLKQLVGPLSTQLADRRSTIVKQACHLLCLLSKELLGDFEACAETFIPVLFKLVVITVLVIAESADNCIKTMLRNCKAARVLPRIAESAKHDRNAILRARCCEYALLTLEHWPDAPEIQRSVDLYEDLIRCCVADAMSEVRATARMCYRMFAKTWPDRSRRLFSSFDPVIQRLINEEDGGIHRRHASPSVRERHSQPSFSQTSAPSNLPGYGTSAIVAMDRSSNLSSGGSLSSGLLLSQSKDVNKGSERSLESVLQSSKQKVSAIESMLRGLHISDRQNPAALRSSSLDLGVDPPSSRDPPFHAVAPASNSHTSSAAAESTHSINKGSNRNGGLGLSDIITQIQASKDSGRSSYRGNLLSESHPTFSSLTAKRGSERNERSSLEESNDAREVRRFMAGHFDRQQMDTAYRDLTFRESNASHVPNFQRPLLRKNVGGRMSAGRRRSFDDSQLQIGDISNFVDGPASLNEALNDGLNSSSDWCARVAAFNFLQTLLQQGPKGAQEVIQSFEKVMKLFLRHLDDPHHKVAQAALSTLADLIPSCRKPFESYMERVLPHVFSRLIDPKEVVRQPCSSTLEIVSKTYSVDSLLPALLRSLDEQRSPKAKLAVIEFAINSFNRYAGNPEISGNSGILKLWLAKLTPLTRDKNTKLKEASITCIISVYNHYDSAGLLNYILSLSVEEQNSLRRALKQYTPRIEVDLLNYMQSKKEKQRIKSYDPSDAIGTSSEEGYAGASKKNIFLGRYSGGSIDSDSGRKWSSSQEPTMITGGVGQNVSSGTQEKLYQNVRTGISSASDLLNPKDSDYTFASAGQNSISRTSPNGSSENIEILDDLSPPHLEKNGLNLTSVDSLEGRHENEVSRELDLGHYMLTSIKVNTTPESGPSIPQILHMINGSDGSPSSSKKSGLQQLIEASVANEESVWTKYFNQILTVVLEVLDDEDFSIKELALSLISEMLKSQKDAMEDSVEIVIEKLLHVSKDTVPKVSTEAEQCLTTVLSQYDPFRCLSVIVPLLVTEDEKTLVACINCLTKLVGRLSQEELMDQLSSFLPAVFEAFGSQSADVRKTVVFCLVDIYIMLGKAFLPYLEGLNSTQVRLVTIYANRISQARNGAPIDADT
The following text describes a protein:
Function:
Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
Sequence:
MTIKAPTLNIGGLGADPLTQRIQEKQKKWKYKIAVLSGKGGVGKSTVAVNLAAALAKMGYFVGILDADIHGPNVAKMLGVDKADVLAERMDDGRFEMIPPMADFMGQVTPIKVMSMGFLVPEDQPVIWRGSLVTKAIKQLLGDTKWGELDFMIIDFPPGTGDEILTVTQSIPLDAAVIVTTPQEVALLDTGKAVNMMKKMEVPYIAVVENMSYLICPHCGNEIDLFGRGGGRKLAEKEGVEFLGEIPIDLKAREASDAGIPIVLYGDTMAAKAFMELAEKLVKKLEEMKGEKAEE
The following text describes a protein:
Function:
Plays a role in the Agrobacterium-mediated plant transformation via its interaction with VirB2, the major component of the T-pilus.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MADEHKHEESSPNLDPAVEVVERESLMEKLSEKIHHKGDSSSSSSSDDENEKKSSSSSPKSLKSKVYRLFGRERPVHKVLGGGKPADIFMWKDKKMSGGVFGGATVAWVLFELMEYHLLTLLCHVMIVALAVLFLWSNATMFIHKSPPKIPEVHIPEEPLLQLASGLRIEINRGISSLREIASGRDIKKFLSAIAGLWVLSILGGCYSFLTLAYIALVLLFTVPLFYDKYEDKVDSYGEKAMAELKKQYAVLDAKVFSKIPRGPLKDKKKD
The following text describes a protein:
Function:
Part of the ABC transporter complex YbhFSR that could be involved in efflux of cefoperazone. Probably involved in the translocation of the substrate across the membrane.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MFHRLWTLIRKELQSLLREPQTRAILILPVLIQVILFPFAATLEVTNATIAIYDEDNGEHSVELTQRFARASAFTHVLLLKSPQEIRPTIDTQKALLLVRFPADFSRKLDTFQTAPLQLILDGRNSNSAQIAANYLQQIVKNYQQELLEGKPKPNNSELVVRNWYNPNLDYKWFVVPSLIAMITTIGVMIVTSLSVAREREQGTLDQLLVSPLTTWQIFIGKAVPALIVATFQATIVLAIGIWAYQIPFAGSLALFYFTMVIYGLSLVGFGLLISSLCSTQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQNLTWINPIRHFTDITKQIYLKDASLDIVWNSLWPLLVITATTGSAAYAMFRRKVM
The following text describes a protein:
Function:
May be involved in MAP kinase activation, epithelial sodium channel (ENaC) down-regulation and cell cycling.
Sequence:
MTLASSLKFPTAQRGELPPVPAWREPRTMGTPASIVCDLPQHPTPKSCTRKRASANIFQGVDLWQLRRLFHSSGDAKAEERAQLIWQCAENRCITQALQQLHRRQRKRRLQSHHRPPSEKGSATRLLELQHFSRLRIEDHTPSCADIENSSNGKEIEDTDQTDHSTVSQHRKKRGMGAADYLHHLHRHQLCSSVLSVLLC
The following text describes a protein:
Function:
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MVKNLLLDIEGTVGSISFVKDKLFPYAASRYESYVNENYESDENLRELGKTPEEALINLRKLHAEGSKERSFKMVQGRIWKKGYESNELTSHLFPDVVPAIQRSLQLGMRVYIYSSGSVPAQKLYFEHSDAGNLLKYFSGYYDTTIGLKTECGSYVKIVGNSNPREWLFLSDNINELKAARKVGLHTGLVVRPGNDPVVDTSGFPVYNSFEILFTE
The following text describes a protein:
Function:
Possesses chitinase activity in vitro toward glycol chitin, carboxymethyl-chitin, colloidal chitin, and the chitin oligosaccharides (N-acetylglucosamine) (GlcNAc)6 and (GlcNAc)5. Hydrolyzes (GlcNAc)6 into (GlcNAc)4 and (GlcNAc)2, or two (GlcNAc)3 molecules. Has the capacity to inhibit hyphal growth of the fungus Trichoderma viride in an agar-plate bioassay.
Sequence:
MAVQKIIITPILVFLVTIFFNVSSSSSSNNSQYQFLNHGVRSAYWPAGDDFSPSLIDTNYFTHILLAFIQPEPISFKLEITKSGIKWGQNFIKALRHRSPPVKTLLSIGGGGSNSTLFSEIASTKQNREIFINSTIEVARKYRFDGVDLDWEFPETQQDMFNLGLLYEEWYNALFAEAKVRRKPRLLLTSAVYYNSTVRLIGKHGPRSYPTQAINKYLDWASPMCFDYHGTWDNNTDFNAALYDSKSEISTNFGLHSWIKSGVRPEKLVMGLALYGRAWELKDPNVNGVGAEAVGPATDTDGSMNYNEILKFNKQSGANVVYDKVAISFYSYAGTTWIGYDDGPSITTKVRFAKSLGLKGYFFWALGKDKDWSISKQASNAWGH
The following text describes a protein:
Function:
Peroxisomal transporter for multiple cofactors like coenzyme A (CoA), flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN) and nucleotide adenosine monophosphate (AMP), and to a lesser extent for nicotinamide adenine dinucleotide (NAD(+)), adenosine diphosphate (ADP) and adenosine 3',5'-diphosphate (PAP). May catalyze the transport of free CoA, FAD and NAD(+) from the cytosol into the peroxisomal matrix by a counter-exchange mechanism.
Subcellular Localization:
Cytoplasm. Peroxisome membrane; Multi-pass membrane protein.
Domain:
The N- and C-terminal portions are exposed to the cytoplasm. Lacks a typical peroxisomal sorting signal. A region between helical transmembrane domains (TM) 4 and 5 and TM1-TM3 or TM4-TM6 are necessary for the peroxisome-targeting activity.
Sequence:
MASVLSYESLVHAVAGAVGSVTAMTVFFPLDTARLRLQVDEKRKSKTTHAVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKAVWVKGQRSSTGKDLVVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIIPTNYKGIIDAFHQIIRDEGILALWNGTFPSLLLVFNPAIQFMFYEGLKRQLLKKRMKLSSLDVFIIGAIAKAIATTVTYPMQTVQSILRFGRHRLNPENRTLGSLRNVLSLLHQRVKRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMGLKSTHKH
The following text describes a protein:
Function:
Plays a role in the transport of magnesium and cobalt ions.
Sequence:
MNDEQQNSNQSENTKKPFFQSLFGRFFQGELKNREELVEVIRDSEQNDLIDQNTREMIEGVMEIAELRVRDIMIPRSQIIFIEDQQDLNTCLNTIIESAHSRFPVIADADDRDNIVGILHAKDLLKFLREDAEVFDLSSLLRPVVIVPESKRVDRMLKDFRSERFHMAIVVDEFGAVSGLVTIEDILEQIVGDIEDEFDEEEIADIRQLSRHTYAVRALTDIDDFNAQFNTDFDDEEVDTIGGLIMQTFGYLPKRGEEIILKNLQFKVTSADSRRLIQLRVTVPDEHLAEMNNVDEKSE
The following text describes a protein:
Function:
Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAGRPLLAPAVTLRPPGPALGSWASLYVGDLDDGVAEGHLYALFCKVGPVASLRICRDVTGRSLGYAYVIFYSREDAKHALDSLNFTPANGKHIRVMFSNRDPTLRLSGKANIFIKNLVPNIDGKSLSDMFGQYGTILSCKVATHFNGQSKGYGFVQFADETSANDAIDSLNGKLVNGKRIFVGLFIRRQERQPNISLSNYTNVYVKNLPKEFTHNDLLQEFGPFGTITSAVIMRDNDGISKCFGFVNYGESECAVEAVKILNGKKIKDTILYVGRAQKKSEREAELKENFECARNEKFKKFEGLNLYVKNLDDSINDLNLRGLFEVFGEIGSCKVMVDSQGRSKGYGFVSFTTIEAVHKAIDGMNRKIVGKKPLYVGVAQRKEERRAMLVAHFARIQNTGVLAPAVPQNFAPRQFYVGPGVPGMFPPQVRAGFGYQQFPQQHFSPWVPSGMTPYTYNMPRPLHHAWRGIQDEKLYPLGEQLEPELGGKVTGILGEAMEALQGRKLEEARDTVDLATIPSSSTLSVSRDAIDPASTASSSSASADGANLAPSPSSSSA
The following text describes a protein:
Function:
Shows both esterase and beta-lactamase activities, with a much higher activity against phenyl esters than against beta-lactams. Shows esterase activity against both long-chain and short-chain p-nitrophenol (pNP) esters, with a preference for shorter chain esters. Hydrolyzes substrates containing beta-lactam ring such as nitrocefin and ampicillin. Functions as an immunogen that activates both humoral and cell-mediated responses.
Subcellular Localization:
Secreted, cell wall. Cell membrane.
Sequence:
MMVDTGVDHRAVSSHDGPDAGRRVFGAADPRFACVVRAFASMFPGRRFGGGALAVYLDGQPVVDVWKGWADRAGWVPWSADSAPMVFSATKGMTATVIHRLADRGLIDYEAPVAEYWPAFGANGKATLTVRDVMRHQAGLSGLRGATQQDLLDHVVMEERLAAAVPGRLLGKSAYHALTFGWLMSGLARAVTGKDMRLLFREELAEPLDTDGLHLGRPPADAPTRVAEIIMPQDIAANAVLTCAMRRLAHRFSGGFRSMYFPGAIAAVQGEAPLLDAEIPAANGVATARALARMYGAIANGGEIDGIRFLSRELVTGLTRNRRQVLPDRNLLVPLNFHLGYHGMPIGNVMPGFGHVGLGGSIGWTDPETGVAFALVHNRLLSPLVMTDHAGFVGIYHLIRQAAAQARKRGYQPVTPFGAPYSEPGAAAG
The following text describes a protein:
Function:
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
Subcellular Localization:
Cytoplasm.
Domain:
Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
Sequence:
MTKKTQDLTSWYDQLLVKAKLICHGEVKGTVCFLNNSWGLWMEIQQLYNDAIANKNQLSAIALTKFQPTTSFCYQVFQVQLPTLSFYSEYQKEKTHIKGFNPELFLINQVGQKQLNDPLVLRPTSEIAFCNLWKKQELSYHDLPLIYNQWTQVFRAEKNTRPFLRNSEFYWQETHGLFVDQSQSEQAAISFWNLYQDLIINKLCIPAFVGLKSESEKFAGAKNTWTIEAIMPDGQSLQCATSHDLGDTFTKSFTISYQSKTNQKMTPSSFSCGMSTRILGAIFLTHSDDYGLVLPWYLASKQVKLYLFDKNNNPKTRALAFLVKDFLEKLKIRFSFIEINNQLGKQLLKGEIEGIPLQMIVDNEKTINIFNRLTRLKTSLTFANLQTEFVNLVNNYHTEMYRKANDLVEQKLARVQTLKEIEQAFKNKKAVLCTVKLTGELEQHLKTKYQVSVRCVFKKSDVTQNCPFTNQPCFDSVLIARAY
The following text describes a protein:
Function:
Plays a role in the ovary in limiting the number of primordial germ cells (PGCs) that develop directly into gametes, allowing them instead to enter the developmental pathway that produces germline stem cells (GSCs) from PGCs and ensuring lifelong production of gametes from these GSCs. Negatively regulates epidermal growth factor receptor (Egfr) signaling. Probably down-regulates EGFR signaling on intermingled cells, a type of somatic stromal cell which contacts PGCs, and the resultant low level of signaling limits the proportion of PGCs which start gametogenesis, maintaining them in an undifferentiated proliferative state.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein. Note=Not uniformly present at the cell membrane but is concentrated at the interface between germ cells.
Sequence:
MAINQGKYKPSICAIDEVDDRSFKLHNSQDEIGGKQQLQQIEGSETAPLTTNQQKLHMDDGSHLTPKDLEAARQDALNEVAAGGAGGRTPAAITPNSTHPSANGLRALLLPGRRSFDALMSLSRKRRILYVTTACLCALLLLIIILLLAFWPEVPFYLRAPLCLDKECVESSRQLLLWANTSKSPCHETYEWACGNFASDYANHEYFVIKRGEWNYETYNEYQELNELNRFIAMLPNSQEGSVESTVSSLYRSCRETDVLDKSQSDLLLKRAINAVYGWQAFRDSNRLQSWEYKRVLVVLQAKHGIFPYYRVTVENGFSNPHDYVITLDEGELGLPDKYFYGNDADEEVVRGYKLLLRDFAINMGIVSREADLFADDIFHYERRIVNHIEDAKADANRPINKLMRLADLKIKAPSLPILESLQAIFPKTKITEDTEVLVRDPEVMHALSVLLSTSDKKPINNFIVWSLARKMLPHLSKEYRTLAETFDHALYGRTASYPRWLICSKVVRDWLPFAVDALQQQPPRQQFETMTSKSRGLNKTQGNEELLKLMFFSLRNQLKDSLEQAKWLEPAARQFIQKKLNEMRLQFGIPDEVLQQPTYLAQYYNELILNNVFFVEHLEWIWTFRRSQMEKKLGPLAILDVIVSEMYTRDNPQAIAYSNKLNMLLVSKVLISSNYYDYRYPVAVNFARIGTDILEALIDNFSTFLLQFNTQSTDISDAAPEIRYAQPDVNCLAAGQPPRLVHELNELSSNALKSFHVTLSAARTAARALSNFVNAIDAGSAIQGSGIDQANTYEALGLTRRLRIPGLRSFNENELFTLSYMQQHCSTTIADKDYARIKPLVESQLAESYLFNATWQHIQFLPRSTNCAAAEATCSNLL
The following text describes a protein:
Function:
Component of the intraflagellar transport complex B (IFT-B) involved in flagellar assembly (Probable).
Subcellular Localization:
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasm, cytoskeleton, flagellum basal body. Note=Localizes to the cytoplasmic and membrane-bound portions of each of the eight axonemes, localizing particularly at the flagellar pores and at the distal flagellar tips. Localizes to the basal bodies. Main cytoplasmic localization in the posteriolateral axonemes. In the examined anterior and posteriolateral flagella, higher levels are observed in the cytoplasmic portions of the axonemes compared to the membrane-bound portions, but lower levels compared to the flagellar pores. Dynamic in the cytoplasmic axonemes and at flagellar pores, accumulating at the flagellar pores.
Domain:
The CH (calponin-homology)-like region shows high similarity to a CH (calponin-homology) domain and mediates binding to the globular domain of tubulin.
Sequence:
MQPPTSTDQLQTITDGLNLPPFERRMTLITLSEILHDPVRAMQLLADVAYQVRPHSLAEDSKAVPPPVKVNAANLEQVAAGITDFTVCLLNLNESRSMADKQAFVQELVLSDSANMRVLLSAILKDLAASRETIYVSKFKLPPVIPADYMVDPQIQTLLSQLREAQSRFTEALNQNRDVQKDQILQKMERLATDKTTFLTRRDKLFDRVKQAKALSVPKEAVRLASRRRVALSEIEELKTQINSQNEIRRAALNAAKAVVNSARGTPANILEASEAENKRLKQEIINLTAEITEKESLAHLIQSEPGQEAIELMENELETLRTDLVKYREMVSTVGSPDEEDNEQEKMSFLNQQITKIKTQRAQLENRLTNARRESAEVDAEVAKRCSSTDMASLMKDIDDMDSIPMLLFKNLLSKGRALKPLHKKAMDEQQLLRKENAIVSRTKDILAAIPNLSAEAPDELTDAGGLRPIGGGKQRVLGSIGGVGLNAKNLMEAKAVLAELDATLQQKKRDLAPRVSELAALKRQCAQLEADTESENQRARTLEVSREGSVYKLRLSVRALELEIDNLKTQAIVTDKKAELLRLELEQADNVREFDRLKREITSENNACKTQMMEIRAKQEELKCNLPNRMAQNKLFKSLVSILEFRKQAALERQEDHAAEMRMDKIRITN
The following text describes a protein:
Function:
Forms a receptor-activated non-selective calcium permeant cation channel. Forms a heteromeric ion channel with TRPC4 or TRPC5 that has reduced calcium permeability compared to the homomeric TRPC4 or TRPC5 channel (By similarity). Also permeable to monovalent ions including sodium, lithium and cesium ions (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MMAALYPSTDLSGASSSSLPSSPSSSSPNEVMALKDVREVKEENTLNEKLFLLACDKGDYYMVKEILEENSSGDLNINCVDVLGRNAVTITIENENLDILQLLLDYGCQSADALLVAIDSEVVGAVDILLNHRPKRSSRPTIVKLMERIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDIYRCLASPALIMLTEEDPILGAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQARNSRELEVILNHTSNDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASYFTFLLLLNLYSLVYHEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKEEAHNKFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFYVYTSSILGPLQISMGRMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTPKEQKDCVGIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAILCTRFSYGEELQSFVGAFIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYMISSLSKWICSHTSKGKVKRQNSLKEWRHLNEKRDENYQKVMCCLVRRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEIRDLLGFRTSKYAMFYPRN
The following text describes a protein:
Function:
Probable GTP-binding protein that may be involved in cell development.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MDEVSPTKHFTSKPLLPTKTPRDKAISHYVNALNSPRNVVKTETPECGIQIIDGDGNFASTDTRERPSLKNYILSKPEFLKRGMDYNAVGILGAQSSGKSTLLNYLFNTKFRILNEVMGRSRTTHGVWMALSGKESNIVVFDLEGTDGSAREDDYSFERKTSLFSLSVCSVLMVNLWSHDVGRFQASNMSLLKTVFELNLQLFVKEETPKTLIVFVIRDREADTPFDQIERDIMEDIMRIWDTVIPPEEFINSPINRFFDFQFTSLPHYEHFYENFVEEVNLMKKKFDPKNKDTYFLPQYNKEIPADGLSCFCEQIWETIKDNKDLDLPSQREMLSRYRCTEISNQIYKEFNDSIKGEMKILKKGNIIEDFKKVFTKQIDAALERYKEVTERYMETIVEEIEEQLKKQLCGLVESLFERQAELMEKAIGKRVKGEFTIIRNEYALLYNKKEFNPMKYQKYSQELSRTKAVIERDWRKQFDDSVPKFLAEKTKEKFNSVCKDIGIAYEDSVSKMTEVMKQHFGDYLESTIKPKITPYLEACKKDMWKNIRNVINIQFTNGFNKLEEGFKTCSNMNKDTIEEEIKKSKTDILNSIKELVIKRKIELPYLLERKFNNMFRFDNKGLPRKWEPTDDVDTLYFAARDETEDILDMYCYFRIEESDDQYKFTINYRDGDLPSESIETLPKGADEEKVILNHEERKELIETLNGFFEKGYLIALREKENSEIKYQIPLYLIVLVVFFGFDEFIAILTNPLLFILTLIIGGGVYIGYKLNLGGVAKNYIQYLLSMSLSSTMEYLRTIPFFTPLIDKVWPKDDNNTEETQEEIK
The following text describes a protein:
Function:
Rho GTPase-activating protein involved in the signal transduction pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MTTTNTSIFGPRVNNSKFNNNNNNNNNNNNNNNNTSNNNNSNIIKPPQVVQETQQQQQAQQQPLQTNEEVCVICKSKNVQVCTGCLMVYYCGAEHQNIDWPNHKSLCSGLNRRNDLLDRAEKSKDLRKKLQSDIFSSGNRVSNSNNNSSIYSNSTGNINNNNNSNNNNIKGGIGGGAVTNSSTVMAPERKSIAISNIKHLQQQIQQTQQTQQQPPPTTTSIPTQPNSSSFNKPTAKKPGTSFKSSSSGDNTPINQSPSSSSSSLVSSTNNNNNNNNNNNNNNNINSNSNNMSGSSGGIKALQNQLQNSINNKPSNTTSNSPNPSPPSSTFVPNSNNNSNSNSSSGSGKSNLNISLKSSTSSSPVTSTYLYNNNNSNSNSNSNNSSTETTTCISSNSNNSSNIENSDNTNEENGMKNIKNKLSQINFGAPPPSFKKPTSKVIENEDNNNSNNDGTLKQSSSSDSIYFNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNFDINNSNNIINNKQSTCSSIDGLSYNNNNSGSSLKNSVPPTTSNTPPRKRSSGGSSSSNNSNIGSNGNRIGFIKEHKKNQSLPDSFVDFYQSNKNQSNGYESLLDNDDNKTRGYGSFNENDDSHEECDDDDDDDDGGGQDGDDGLDGTEFKRGRNRPTGLRTNNNAVFEWESGTIEYSTNNTSQHKKLGVGSRGGNSFSKDTQSQSTNSTTTDDHQTGSILNSNSGSSDDLQQQQTQTQQQQSQLSAGVGRIAGKFRMIGGDIKKKAAIVGTLTKNKVSEVTSKSKSSTSVNNNNNDEVDHNENNNNNNNNINNNNNNNNNNIENIIFGIPLEEAVKKSATLHPLIPDVIYKSIEYIREKGIQEEGIFRLSGSANAITLLKNEFDRGVNVDLYQQLDQHVVSGILKLYLRQIPETLFTQDFGEELEELRVGGNSSDAISKRIAGSIILLQRLPESNRCILHYLCNLLNAISFEPSTKMGTVNLAIVFAPTLGVSVEVMTCLISYYDEIFGIQTYNYNS
The following text describes a protein:
Function:
Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MMFLIPYLIGPLKKIISVLTGFSDDLFILYTAHPILTVTVIALTTLSLSFVVQILLSFTNYLILILLPSSFWASKGSILKLQLQEKNKAGKLVPSKKLRPWAVVTGASDGIGKEFALQLAHLGYNIVLISRSVDRLKLVADLISTQDPLSKTLILPVDYAAASTHDYDTIAAALRPLHITVLINNVGISHAFPISFVEETSDMVHSIVQVNIMAQLTMTRIILPQMLARKEGTIINVGSMAGKVPSAYLSVYSGSKAFLRFWSQALALEVKPSNIHVEHVNTYFVATAMSKIRKASWLAPSPKLYVQSVLANVGNSINSTPYPPHGFVSWMFERFAPEHLLMKLSCDMHLDIRKRALAKIAREAKKN
The following text describes a protein:
Function:
3'-to-5' exoribonuclease (RNase) specifically targeting single-stranded RNAs. Triggers miRNA accumulation in RNA-induced silencing complex (RISC), composed of miRNAs and AGO proteins, by degrading uridylated cleavage fragments. Required during plant growth and development.
Subcellular Localization:
Cytoplasm.
Sequence:
MSSSIVKIGIDSIKTTVTEKERDINRLVKTFLSNKNNRKKIIGLDTERVQKGRKLNKTVLLQLCDGDNCLIVQLPDEDEDEGEGEDDNLPLPLFNFLNLPEFTFVGIGINKTMMRLESEFGLTCKNVVEIGPATWNLTNMTTDVKFRISAIVSTERPSNAVLEDWEKFVLNKNQIKLAASNAYFAFGIGNILLDVQILS
The following text describes a protein:
Function:
Catalyzes the desulfonation and deamination of L-cysteate, yielding pyruvate, sulphite and ammonium. Is involved in a L-cysteate degradation pathway that allows Silicibacter pomeroyi to grow on L-cysteate as the sole source of carbon and energy. To a lesser extent, can also act on D-cysteine in vitro, leading to the production of pyruvate, sulfide and ammonium. L-cysteine, L-cysteine sulfinate, and 1-aminocyclopropane-1-carboxylate (ACC) are not substrates for the enzyme.
Sequence:
MHLARYPRRFIAHLPTPLERLDRLTAELGGPEIWIKRDDCTGLSTGGNKTRKLEFLMAEAELQGADMVMTQGATQSNHARQTAAFAAKLGMDCHILLEDRTGSNNANYNNNGNVLLDHLHGATTEKRPGSGLDMNAEMEKVAEKFRADGRKVYTIPGGGSNPTGALGYVNCAFEMLNQFNERGLKVDHIVHATGSAGTQAGLITGLQAMNAQIPLLGIGVRAPKPKQEENVYNLACATAEKLGCPGVVAREDVVANTDYVGEGYGIPTESGLEAIRMFAELEAILLDPVYSAKGAAGFIDLIRKGHFKKGERVVFLHTGGAVALFGYDNAFDYSGRWVA
The following text describes a protein:
Function:
In vitro, the reduced form of Rv2466c catalyzes the reduction and activation of TP053, which is a thienopyrimidine derivative drug that can kill both replicating and non-replicating M.tuberculosis.
Subcellular Localization:
Cytoplasm.
Sequence:
MLEKAPQKSVADFWFDPLCPWCWITSRWILEVAKVRDIEVNFHVMSLAILNENRDDLPEQYREGMARAWGPVRVAIAAEQAHGAKVLDPLYTAMGNRIHNQGNHELDEVITQSLADAGLPAELAKAATSDAYDNALRKSHHAGMDAVGEDVGTPTIHVNGVAFFGPVLSKIPRGEEAGKLWDASVTFASYPHFFELKRTRTEPPQFD
The following text describes a protein:
Function:
Negatively controls the salicylic acid (SA)-mediated pathway of programmed cell death in plant immunity.
Sequence:
MENRKGGNFSVPSSEALTTTLRNAIQALGRGFDVTSDVRLLYCKGAPGSRLVRIEEGQNRDLELSHGFLLPNVPADIDCSRGNSGTQRISVCSFHEMAEEFNVRSGVKGNIPLGCFNAMFNYTGSWQVDAASTKSLALVGYFIPLYDVKLAKLTLVLHNEIRRAVPSSWDPASLASFIENYGTHIVTSVTIGGRDVVYIRQHQSSPLPVSEIENYVNDMIKHRFHEAESQSITGPLKYKDKDITVIFRRRGGDDLEQSHARWAETVPAAPDIINMTFTPIVSLLEGVPGLRHLTRAIELYLEYKPPIEDLQYFLDYQIARAWAPEQSNLQRKEPVCSSLQFSLMGPKLFISADQVTVGRKPVTGLRLSLEGSKQNRLSIHLQHLVSLPKILQPHWDSHVPIGAPKWQGPEEQDSRWFEPIKWKNFSHVSTSPIEHTETHIGDLSGVHIVTGAQLGVWDFGSKNVLHLKLLFSKVPGCTIRRSVWDHTPVASSGRLEPGGPSTSSSTEEVSGQSGKLAKIVDSSEMLKGPQDLPGHWLVTGAKLGVEKGKIVLRVKYSLLNY
The following text describes a protein:
Function:
Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain. Prefers cross-linked murein in vivo.
Subcellular Localization:
Cell outer membrane; Lipid-anchor.
Sequence:
MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQKAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSDRKKAISKINDLDADEFLEHVARNHPAPQAPRYIYKLEQALDAM
The following text describes a protein:
Function:
Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3. Histone methyltransferase activity has not been confirmed in other species. Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR. Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation. In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival.
Subcellular Localization:
Nucleus.
Sequence:
MEDSGIQRGIWDGDAKAVQQCLTDIFTSVYTTCDIPENAIFGPCVLSHTSLYDSIAFVALKSTDKRTVPYIFRVDTSAANGSSEGLMWLRLVQSARDKEEQNLEAYIKNGQLFYRSLRRIAKDEELLVWYGKELTELLLLCPSRAHKMNGSSPYTCLECSQRFQFEFPYVAHLRFRCPKRLHSTDANPQDEQGGGLGTKDHGGGGGGKEQQQQQQQQQQEAPLIPGPKFCKAGPIHHYPASSPEASNPPGSAGAGSAKPSTDFHNLARELENSRGSSSCVAAPGVGSGGSGHQEAELSPDGVATGGCKGKRRFPEEAAAEGGGAGLAGGRARFSERPLATSKEELVCTPQQYRAAGSYFGLEENGRLFAPPSPETGEAKRSAFVEVKKAGRAVGLQEEAAATDGAGGTAEDPDAGGGVAGGGSNGSSTPAAGSPGAPEKLLAPRPGGSLPGRLEGGSPARGSAFTSVSQLGGGGGAGTAGTAGGSGGGQTAASDERKSAFSQPARSFSQLSPLVLGQKLGALEPCHPGDGVGPTRLYPAAADPLAVKLQGAADLNGACGPLASGGGGGLPKQSPFLYATAFWPKSSAAAAAAAAAAAGPLQLQLPSALTLLPPSFTSLCLPAQNWCAKCNASFRMTSDLVYHMRSHHKKEYAMEPLVKRRREEKLKCPICNESFRERHHLSRHMTSHN
The following text describes a protein:
Function:
Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
Subcellular Localization:
Cytoplasm.
Sequence:
MKFTLSTVTKCSGRLGVLGGLDRLPNLSLQTPAFIFHTKGGSIPHLSKEAMQHVSGDPSCFLHLSISNTLHMQEAIKASRITIAEFIAQSNCATLLFVRDPSEPPIPGLPEKDSLPIYTRNGRRNITLEQYMTLVETFRPDAYVPLYDGDTDASSSKKRDQKSLDRTEKFVEQCLEWHRKSDALQSSCLIGPVVGGYNEKLREQSVAFLRQSDDAFAGYLIEGLHMHGPSVARMDGSAALGIVANVCKQLPEAKVRLCFGSYDPALVLEMVAAGVDVFDTSYVYLKAAQEHRALVFSFDVTSTEQEHVTELDTTDARWAEDFGPLLPGCKCYTCQKHSRAYVHHLHNTREMLGPILLMMHNLHHYVEFFKAIRHHVANDSLPELRNHLAGQKSLPPYEPPKEEKLPMPAAQKAELMEPMEDLGEKQNKKQRA