lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.
Sequence:
MLKVYPAFIQQLPVWLQQPHYSKRIKNMNGWIDLIQMTNTYLITALHFCGALNSSKRVSPYPSSRSSPPSPFFLSTSRSISCHPSSPSPSLAPPLSLFTTLFLPFISPPASWCSLLLLFDCSPPPLLSPLFLPLFLSIFKPLTLALSSLISLSLPFHLFLSLSSTSLQPPEARQLAALHPREDVDLVTEVKMAMSSILNADDIKKALDAFAVADSFDHKKFFEILGLRAKSADDVKKVFTVLDADNSGYIEEEELKFVLKGFAKDGRDLTDKETKAFLKAADKDGDGKIGVDGKQKHPIVLPDKCQRRQKCVEMTHSYPCW
The following text describes a protein:
Function:
Mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline), the primary signaling neurotransmitter in the autonomic sympathetic nervous system. Is responsible for norepinephrine reuptake and clearance from the synaptic cleft, thus playing a crucial role in norepinephrine inactivation and homeostasis. Can also mediate sodium- and chloride-dependent transport of dopamine (By similarity).
Miscellaneous:
MISCELLANEOUS: This protein is the target of psychomotor stimulants such as amphetamines or cocaine.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Cell projection, axon. Synapse, synaptosome.
Sequence:
MLLARMNPQVQPELGGADPLPEQPLRPCKTADLLVVKERNGVQCLLASQDSDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLNLPWTNCGHSWNSPNCTDPKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVIVVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINCVTSFISGFAIFSILGYMAHEHKVNIEDVATEGAGLVFILYPEAISTLSGSTFWAVLFFLMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCVVTISTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYTYPPWANWVGWGIALSSMILVPAYVIYKFLSIRGSLWERVAYGITPENEHHLVAQRDVRQFQLRHWLAI
The following text describes a protein:
Function:
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
Subcellular Localization:
Nucleus.
Sequence:
MPRYYCDYCDTHLTHDSPSVRKQHCAGYKHKANVRQYYQQFEEQQTQSLIDQKVKEHLGQTAAALAQQQVGGAVYSHLATLGGGYKPMAAPGLLRPPVLAAVRPPVLPPPSGPSSGYGSGALPSYRPPVVPPPGGSSNQYYNNNGPSQYSTSNGAPQYSVNNSLVPQSYSSSSSGAQSQYMSSANGGQAQYQTSSGGTQQQQYSNGPTRPPISSTYNQGPMYQR
The following text describes a protein:
Function:
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly. May regulate electron transport between the quinone binding sites of the reaction center. PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation; Required for association of HliB and Psb34 with PSII.
Subcellular Localization:
Cellular thylakoid membrane; Single-pass membrane protein.
Sequence:
MAQRTRLGDILRPLNSEYGKVVPGWGTTPVMGVFMALFLVFLLIILQIYNSSLILEGFSVDWAG
The following text describes a protein:
Function:
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
Subcellular Localization:
Secreted. Bacterial flagellum.
Sequence:
MIINHNLNAMNAHRQMAINTGNNGKAIEKLSSGLRINRAGDDAAGLAISEKMRGQIRGLNQASRNSQDAISLIQTAEGALNETHSILQRMRELTVQAANDTNVTVDRENLQKEVAELQSEINRISSQTQFNTKSLINGAVSKDADAMTFQIGANSGQTIKLTIGSMDAKTLNVDKIKLDDTAANVTKQIATIDNAINSVSKERAKLGANQNRLEHTIANLDNSAENLQAAESRIRDVDMAKEMMNFTKTNILTQAAQAMLAQANQAPQGVLQLLR
The following text describes a protein:
Function:
Digests TAMe (p-toluene arginine methyl ester), but not ethyl N-benzoyl-L-tyrosinate (BTEE).
Subcellular Localization:
Secreted.
Sequence:
MKILLFLCFLVSVAFAKPPTIQLKSNTKSQNGFIVGGTEAVDGDAPHQVSLQHTSHFCGGSIISERWILTAAHCIDADDLSNPGGMSVRYNTLNLKSGTLVKVKSIKVHEQYSNVTSDNDIALLETVASMNLNQTNAVAAKLPAKGNDPQDGDLFLSGWGTLHSGDTTIPTNLQKVTVPLTNRSVCAEAYTGIVNITENMFCAGKMGIGGVDSCQGDSGGGAMLNKELVGVVSFGVGCGDPKYPGVYTRVSQYLDWIELSAKSSATTLVAVNITLFLTLFIGAIW
The following text describes a protein:
Function:
Required for both formation and activity of the chloroplast NAD(P)H dehydrogenase (NDH) complex of the photosynthetic electron transport chain. Functions in assembly or stabilization of the NDH complex; probably involved, together with NdhO and NdhH, in the formation of an NDH subcomplex A assembly intermediate (NAI500).
Subcellular Localization:
Plastid, chloroplast. Plastid, chloroplast stroma.
Sequence:
MASTSTLLLPSLSSKNLHIAVPIRTNSFVRRTTKFSTKCSSNPESKDQFINLTPAPESINTTSAEKFPIEKRRRSEIIRDRTQRGIEKPEPPNFEIGWKRTKEINLEKPKGYVIMDFLEKFEALMAREFGSKELLAKAGEIVAERAREEAEVLRDEGKVEERMVTELFRVLKLMEMDLAMVKASVKDETLSQRIEQARARCRQAILVANSF
The following text describes a protein:
Function:
Probable transcription factor. Required for differentiation of AIY interneurons, acting downstream of LIM/homeobox protein ttx-3. Modulates gene expression, acting downstream of AMP kinase aak-2/AMPK signaling. Modulates lifespan.
Subcellular Localization:
Nucleus.
Sequence:
MDTHLPFQTLPVSTPLPVSSSSLTDVLQTIAALQACPTSCIPSTSTGMLSPNLPFSATIPRVNLFPPSQPANSLILPTIPAQPFIPNPSLLQANPSAVEALANALFATTSRRASCPEPPASSQATVTLQVPSTGSPERRRYSETNMEVLLREQLAQLMPPTSQLPGMPGCYYQHVPAAGTSGIQGSLDAALMGAVPLAMNSMAHSRRAANHRKARTIYGTTQTQQLEDMFKGQMYVVGAERENLAQRLGLSPSQVRIWFQNRRSKHRRKQQEEQQSTTLEEKSEEIGKDEEEDDEEDEDDVKVLN
The following text describes a protein:
Function:
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
Subcellular Localization:
Cytoplasm.
Sequence:
MMRILVSNDDGVNAPGIKALTEALAEIATVMTVAPDRNCSGASNSLTLTNPLRINRLDNGYISVHGTPTDCVHLAIRELCDGEPDMVVSGINAGANMGDDTLYSGTVAAAMEGRFLGFPAVAISLNGKAFKHYHTAAVYARRIVQGLLAHPIASDQILNINVPDLPLDEIKGISVTRLGARHKAEGIVRTQDPAGREIFWLGPPGLEQDASEGTDFHAIAHGYVSITPLTVDLTAYRQLSILQNWVDKI
The following text describes a protein:
Function:
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Sequence:
MNYYGNYYGGLGYGYGGFDDLGYGYGCGCGSFRRLGYGGGYGGYGYGSGFGGYGYRSCRPSCYGGYGFSGFY
The following text describes a protein:
Function:
Forms the apical lamina, a component of the extracellular matrix.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Secreted, extracellular space.
Sequence:
MDDVSDTTVLICDALSLTWTGTLPQCNRVNCPEPPVPNDGSVFGSGRYYGDVITYACDTNYRLYDPSVSRTCSEDGTWSGESPECFPDLSSPDVCPSGSWQYGNNTCFRANSAWRTWKNARDVCASGSPVGQLATVVDEDVQTFLEDKLGEVAGVATTHWIGGSYGYIWYWDDSGLPLDYFSWAWEEPSSTSDNIQCVFLSSLPNPGGDKDHDYNWNDDDCLENEVSGIPNYVICEYDMACSSISNLILSAYRKYDYDGKCEVFVTDPRNWNDGRAFCSGTSGRVVEIYDGVKQDFLVEKARSVDSSSRSNWWIGAKRKTSAGKIWHWVDGSPITNFYWGSGEPSNPDTEQCLDLLKTSNHKWNDDRCSSTADYLCQYTGPKEPQRCYDPGEPAHGTYEPSNSDWLYGSHVTYSCDEGYTLDGNITRIYCNLNGTYSPGVSKCIPVSCGGVYPSLDNSTPNCAGSDFRDIVFYVCDNGYYPVGEMSAVCQPNGSWSQARGQCQEFDECESSPCLFGSTCLDMINYYQCDCTDGYNGTNCEFEIDECFSNPCQNDATCYDVINGYTCSCTSGYDGIHCENEIDECSSNPCQNGATCSDFINMYNCTCLPGYEGMNCENEIDECSSNPCQNGASCSDHIDSYNCTCLPGYEGIHCESEIDECTSNPCQNGGTCNDFVDFYNCSCQAGYDGLQCQNEIDECSSNPCLNGATCTDFVDFYNCSCQAGYDGLDCQNEIDECSSNPCQNGGTCNDFVDSYNCSCQAGYDGLHCQNEIDECSSNPCQNGATCTDFVDFYNCSCEAGYDGLHCQNEIDECSSNPCLNGATCTAFVDFYNCSCQAGYDGLHCQNEIDECSSNPCQNGAICTDFVDFYNCSCEAGYDGLHCQNEIDECSSNPCQNGATCTDFVDFYNCSCEAGYDGLHCQNEIDECSSNPCLNGAICTAFVDFYNCSCHPGYDGLHCQNDINECMSNPCFNGATCFDSIDFYNCSCSAGYEGINCENDVNECWSNPCQNGATCLESIDFYNCFCAGGYEGINCEIEIDECSSNPCLNGATCTDFVDSYNCTCLQGFDGIHCQSEINECSSNPCMNGGTCFDAVDFYNCTCQTGYHGINCESEVTECSSNPCLNGATCNEFVDFFNCSCPRGYDGIHCQKDIDECLSNPCQNGATCSDAIDFYNCSCIPGFDGVNCENDINECLSNPCHNGATCSDETDFYNCICIPGFDGVNCENDIDECLSNPCQNGASCSDAIDSYNCSCIPGFDSVNCGNDINECLSDPCHNSATCSDEIDFYNCSCIPGFGGIHCENEIDECVSNPCYNGATCMEFVDFYNCSCQAGYDGPHCENDINECLSNPCQSGATCSDQINFYNCSCIPGFDGINCESDINECLSNPCHNGATCSDEIDFYNCTCKAGYHGVNCEIEINKCFSNPCQNGATCTDIADFYNCSCTLGYDGINCENEIDECLSSPCQNGGSCSDYINLYICTCLDGYEGSQCEQEIDECLSNPCLNGATCKDSINIYSCTCPKGYDGIHCEKKSSGEKANVALIASLSVLGFILLIAITIVTCWLTHRQSKVTPDELELDPTTKNETRSTVAWDDDGDGGRPASPMSVVMPNGDLTYIFDVEESMYEKWT
The following text describes a protein:
Function:
Involved in resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region. The C-terminal region is a kinase that phosphorylates several 4,6-disubstituted aminoglycosides.
Sequence:
MRFAKLSDGLSDGIVTLSPLCLDDVDAHLAGGDERLVRWLSGMPSTRASVEAYIRHCREQWVTGGPLRSFGIRTVAETIVGTIDLRFDGEGLASGQVNVAYGLYPSWRGRGLATRAVDLVCQYAAEHGATEAVIKVEPENSASARVALRAGFAFVRRICEQDGTVFDRYERVLRAKMHADEVDIDEDLVRRLLRAQFPQWADLPIAPVRSAGTDNAMYRLGEDLAVRIPRIGWAIESLRTEQQWLPRIAAHLGVASPVPVGLGSPAEGFGWPWSVCRWVAGENPSAAEFVEPNRAVEDLADFITALRATDPMGGPPAKRGAPLGEQDAEVRAALAALDGIIDVHAATAAWESALRVPPYAGPPMWFHGDLSRFNILTAQGRLTGVIDFGLMGVGDPSVDLIIAWNLLSAPARAQFRVAVGAADDDWMRGRGRALAIALIALPYYQDTNPPLAASARYAIGEVLADFRYGARPGC
The following text describes a protein:
Function:
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
Subcellular Localization:
Cytoplasm.
Sequence:
MDKKFYITTLGCPKNIADSMSMHHSLLEEGFTLASLPEESDFHFINTCTFIQSATEETIQTILSAAQVKKQNHQKLVVVGCFAERYPDNIHSEIPEVDLFFGTGKYSQAGKILREKFPELSPSQLEFNDSLLERWKLSSKIENYSKPYAYVKVSDGCNRGCSFCIIPSFRGKFVESPLDDILRDTNRAIRAGAKEICLVSQDTVYYGRDSEILLDMVRKVAEIDSLEILRLLYLYPDKKTEKLIRLMGETSKIAPYLESPLQHVSSKILKVMNRTGESSYFKDLFSLAREVKPGLEIRTSFIIGYPGEEPEDVDQILRFIEDTRPEKVNLFSYSPQEGTKGAQLKQTVSEKEKSKRINLIRDSHLEILEEIHESRIGRTYDAIVDGIEDGQVVVRRFQDAPEMDEVVYVDDVSLIPGRIGKVRIDSFYEYDMNGTWV
The following text describes a protein:
Function:
Required for the maintenance of centromeric cohesion during interkinesis, until meiosis II. Required for regular configuration and segregation of sister chromatids in meiosis II. Also required for centromere cohesion during meiosis I. Involved in spindle organization at the end of telophase I and in meiosis II. Required to prevent precocious release of pericentromeric cohesins during meiosis, but not for cohesion establishment and monopolar orientation of kinetochores at meiosis I. Involved also in somatic development. Regulates mitotic cell division and ploidy stability in somatic cell types. May be involved in the organization of microtubules dynamics. Involved in abiotic stresses and mono- or divalent ions tolerance and may play a role in maintaining meristematic activity under saline conditions. PANS1 and GIG1 are part of a network linking centromere cohesion and cell cycle progression through control of APC/C activity. Regulates the number of dividing cells in root meristem and is necessary for the anaphase onset control through an APC/C-mediated pathway. Involved in maintaining correct chromosome arm cohesion under stress conditions.
Miscellaneous:
MISCELLANEOUS: Patronus is Latin for protector.
Subcellular Localization:
Nucleus. Cytoplasm. Note=Excluded from the nucleolus.
Domain:
The DEN-box is not essential for the meiotic function.
Sequence:
MANMNALQQMIFPDENAPIHRKKSVTAASVKSKGTVLGQKKPGGARKALNDITNKSGIHAKAAASSKNKQIASAAVKEIDIAGERFLHDHSKCIKEQQNLWDDHYSADLMLLHHGSSIKEKHLNWDIEKMDAKDDLTYEEPEEMASPKFSDWLKNSTPWRSPIRHGSMMPSTPLAWRFDSCEFTLKEDSDDLF
The following text describes a protein:
Function:
Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.
Sequence:
MSSARFVARTATWFRRRSRWILLILTAFFISYLLIVQRQSFAYLTNPSIPSEWMQGGQKDGAIDHPKDLLKLESRTELLATPRKSAEICHQEMKAETKHDFDLHDIYENVIARAGKQEKSASTRPAAQGKLRVFVLPFTHVDPGWLSTFDEYSKDTKTILDNMHLFMMKNPKMRFMWAEFVFFERWWKEQTEEVKKDVRELVSSGRLELASGSWVMTDEANAYFPVSVDNIVEGHQFIQKEFGRLPTVVWSNDPFGYSNSVPYLFTQAGMNRTVINRIHHGIKGHLQSQRAIPFKWKQYFGDSSMLTQVLPYTHYDILNSCGPNAGSCCQFDFRRITKWSCPGPRPVPITPHNVKEKSKLLIDSLRQMASMYEAPVMLMMHGDDFRFDNEEEWPQQHDNFLPLFDEINKGDQVEINFGTFSDYFNELEKWYRTEKIEPPSVTGDFFPYMCALGDYWTGYYTTRPFYKKQSRQTHHLIRTADLLSAEAGLTGTYEKLTKARRILALFQHHDAITGTSKIHVMKDYSKQLFDAGNIAKSVIEESIRKMEKTDEKTKMIEYSVKVDETIEKEMLNSHLYLQFSSLRSTFGCFSTVVDSDGNEVEAQIEPTLIHEKWRSEGVILSFRVTLPPLSSRVYVLHHSDSPSKTTIVRLSAPSASVETLKGKLPSIFKVSSISSPTVTLTNGHLTTTHYAGSGMMKSAKSSIVGDVSLELGVTQLTGSNGGAYIMRTHGVARNVSMTSVLFVSGSIQSSAYSLSTTVQHWTTVRDLPGTLSDQVHVSMRVDLRAEHNTEMVWSVVSEGDDSYSFYTDSVGLQMLRRKSYSTLQTPANYYPMPTAAILEDGKKRITVVADVEHGVMETGKMGMEIMIDRMLNQDDGKGLGQGEDSYPTDLLPVQMYFTLVIEKRNGAANTTHHTYNSVAGTLALQEILYPTVPLVTTKVSSSHFPQKSFPCDLQLLTTRLISPTKMMITLFRNGIDCTIDSTVSCSDSKITDAIRSLVNRLGGKSSITRTLLNGIEVLQEYSSIDELDETIVPPPQKFTTLVFNV
The following text describes a protein:
Function:
Potential negative modulator of chondrocyte differentiation. Inhibits collagen fibrillogenesis in vitro. May influence chondrocyte's differentiation by acting on its cellular collagenous microenvironment.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MGVRPLLWASPSGACLRAQQPSGPWMLVPQDLSPWAPPWPVLNLQPHHRLWRMPPAPRLGLDHRTPRRLINMVTTQSQGLSLVLLLPLLLLLGPTWQATGQRCPWTCVCDNSRRHVACRHQNLTEVPNAIPELTQRLDLQGNMLKVIPPAAFQDLPYLTHLDLRHCQVELVAEGAFRGLGRLLLLNLASNRLTALPQEALDGLGSLRRLELEGNMLEELRPGTFGALGALATLNLARNALVYLPAMAFQGLLRTRWLQLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGLALSQAQGLVHLELGHNPFTYMGEEDGLALPSLRELMLDHGALQALDPRAFAHCPHLHTLDLRGNQLDTLLPLQVPGQLRRLWLQGNPLWCGCQARPLLEWLARARVRSDGACRGPRRLRGEALDALRPLDLRCPGDGAEEEEEELAALRPRGPPSTPKEEDGAAKPCPHVCVCASESRHSGCEGQGLQAVPRGFPNDTQLLDLRQNHFSLVPRAAFPGLGLLVSLHLQHCGITELEAGALAGLGSLMYLYLSDNQLSGLSAAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLAGVRALRWLYLSGNRITQVSPGALGPARELEKLHLDRNQLREVPTEALEGLPALLELQLSGNLLRTLSHEAFRPVGRSLQHLFLNSSGLEQISPGAFSGLGPQLQSLYLQKNQLQALPALPGLSQLELIDLSGNPFRCDCQLLPLHRWLTGLNLRVGATCAAPPRARGQRVKAAAAVFEACPGWAARKAKRTPSARRITP
The following text describes a protein:
Function:
Transcription activator required for the culmination, at the time of the fruiting body formation. Regulates genes involved in the cell differentiation within the fruiting body.
Subcellular Localization:
Nucleus.
Sequence:
MTMINPLSYPVPSQYSYTYNNNNNNSNNSSNNNSNNNSNNNNNNNNNCGVPNVSYGSNLNQQSMAQDLRVPEQYSISSPSPKKRPFNSTMTTSPPTPTLLSNSPYIHGSHIVPQYSPQLQNVYNTPHQSSHSIHQPPQQTPNIFNNNNNNNNNNEKSNNQNFGNTLFNSITNNSSNSSNSLIQQNNLTNNGSSSSSSSSSSTNFNQNNNFINSSNDSIYNSNICSFYGNTSSSSSSSLNGIESPPSVELMDDDIEDQLREYISPVIWGMMDNYAREQFYNAIVEFINEEISFRSLLLELRVIAVMDVNYKSIFQFLVDLFLSIEPNQKMVNYLRDNGVEENEFNIDLKSLELSSDNDSNQKKKRERIRKSVSRGLRNPPNKWAKEESQKLIQLVHEHGDKQWKKIAHQIGGGKTGAQCAQHWKRVLCPAIRKGSWDEDEESKLFNLVEKHGQSWKNVASEIRTRTDIQCRYQYFKSCMSREVQWSSREDEILQKKVSENNQQDGTININNTRDISWMDVSKAMARGRQTKIPRTALECKTRYFQLNFGGAPIQIVVPHNDDHLNNPHSPLNSLLQDQNCY
The following text describes a protein:
Function:
A transpeptidase that forms peptide cross-links between adjacent glycan strands in cell wall peptidoglycan (PG). Part of the divisome machinery that synthesizes the septal cross wall. Beta-lactams inactivate the PBPs by acylating an essential serine residue in the active site of these proteins.
Miscellaneous:
MISCELLANEOUS: The mature form of PBP2x contains an unprocessed signal sequence followed by a membrane-anchoring segment.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKDIKKITLTLGD
The following text describes a protein:
Function:
Directly involved in telomere replication. Associates with telomerase and during its interaction with trt1, telomerase activity is promoted.
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MSQQLSSNEICEEQGKLVKALCEAAQGGFKHDLYEKIIAIEIEVEKKLLNRLKSIQTNTFERPDIIWSCCHYKIIQHFRSRFREIHPRHVVEKKKTKKVFFKFLKTCAIFYQTCISELISKFQLDSYRPFFCKWTSSATVSSTISNDEMSSIPEASYSRNHMEALECVYNCFIYLGDMARYSSTCLKKRGAYDRALGFYDLAHRTLPGNGMHRNQIAVVWASDECIVESIYWFSSALCSEDPPKSALLNLLKQLIAFYRRCFAVHFEFVSPMMILLFIISDCCIHSLKEIQPFKCPSIMVKDLENSLLQSNIRNVGYEKKNLYYISSAFSNLLHCRYFNCNDRLRSFYYRFSSWLFHQTLACAKEVESERAPTSYLTSCLPSIKVILARVLESSPAFGFIERNELEQLSYHFRICEKFFKESSENKMLNLFEDYNEFGLCKSFICLFKRLNEDIIGPKLNINPPDYTTHPFSESIKRFYQISKILNLLLS
The following text describes a protein:
Function:
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit Sdhb of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MTGRHVSRVRSLYRRILQLHRALPPDLKALGDQYVKDEFRRHKTVGPGEAQRFLKEWETYAAVLWQQAKDSRQSSSGKACFGTSLPEEKLNDFRDEQIGQLQELMQEATKPNRQFSITESTKPHL
The following text describes a protein:
Function:
Transcriptional activator that binds to the G-box motif (5'-AACGTG-3') found in the promoter of the jasmonate-induced gene LAPA1. Acts as a negative regulator of blue light-mediated photomorphogenesis and positively regulates root growth. Promotes growth in response to the phytohormones abscisic acid (ABA) and jasmonate (JA). Binds to the G-box motif (5'-CACGTG-3') of the RBCS-3A gene promoter. Acts downstream of the jasmonate (JA) receptor to orchestrate JA-mediated activation of plant responses. Positively regulates both wound-responsive and pathogen-responsive genes through MYC2-targeted transcription factors (MTFs) involved in early response to JA. With JA2L forms a transcription module that regulates wounding-responsive genes. With ERF.C3 forms a transcription module that regulates pathogen-responsive genes. Plays a critical role in orchestrating JA-mediated defense gene expression during Botrytis cinerea infection. Negatively regulates defense responses to root-knot nematodes, potentially by mediating crosstalk among the hormones strigolactones, abscisic acid (ABA) and jasmonate (JA). Regulates the termination of JA-mediated defense responses by specifically binding the G-box (5'-CACATG-3') motifs in the promoters of MTB1, MTB2 and MTB3, which are transcription factors that negatively regulates JA signaling. May be involved in JA-induced chilling tolerance, possibly by ameliorating the antioxidant enzyme system of fruit and increasing proline and lycopene levels.
Miscellaneous:
MISCELLANEOUS: Plants over-expressing MYC2 exhibit increased number of branches with reduced internode distance. Plants silencing MYC2 exhibit increased susceptibility to infection by the fungal pathogen Botrytis cinerea. Plants silencing MYC2 show decreased susceptibility to infection by root-knot nematodes.
Subcellular Localization:
Nucleus.
Sequence:
MTEYSLPTMNLWNNSTSDDNVSMMEAFMSSDLSFWATNNSTSAAVVGVNSNLPHASSNTPSVFAPSSSTSASTLSAAATVDASKSMPFFNQETLQQRLQALIDGARETWTYAIFWQSSVVDFSSPSVLGWGDGYYKGEEDKAKRKLSVSSPAYIAEQEHRKKVLRELNSLISGAPPGTDDAVDEEVTDTEWFFLISMTQSFVNGSGLPGQALYSSSPIWVAGTEKLAASHCERVRQAQGFGLQTIVCIPSANGVVELGSTELIVQSSDLMNKVRVLFNFSNDLGSGSWAVQPESDPSALWLTDPSSSGMEVRESLNTVQTNSVPSSNSNKQIAYGNENNHPSGNGQSCYNQQQQKNPPQQQTQGFFTRELNFSEFGFDGSSNRNGNSSVSCKPESGEILNFGDSTKKSASSANVNLFTGQSQFGAGEENNNKNKKRSATSRGSNEEGMLSFVSGTVLPSSGMKSGGGGGEDSEHSDLEASVVKEADSSRVVEPEKRPRKRGRKPANGREEPLNHVEAERQRREKLNQRFYALRAVVPNVSKMDKASLLGDAISYINELKSKLQNTESDKEDLKSQIEDLKKESRRPGPPPPPNQDLKMSSHTGGKIVDVDIDVKIIGWDAMIRIQCNKKNHPAARLMAALMELDLDVHHASVSVVNDLMIQQATVKMGSRHYTEEQLRVALTSKIAETH
The following text describes a protein:
Function:
Substrate recognition component of an ECS (Elongin BC-CUL5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Specifically binds to the methyltransferase cofactor S-adenosylmethionine (AdoMet) via the N-terminal AdoMet binding motif, but does not display methyltransferase activity. May provide an alternate maintenance pathway for modified proteins by acting as a damage-specific E3 ubiquitin ligase adaptor protein.
Subcellular Localization:
Cytoplasm. Membrane; Lipid-anchor.
Sequence:
MGGAVSAGEDNDDLIDNLKEAQYIRTERVEQAFRAIDRGDYYLEGYRDNAYKDLAWKHGNIHLSAPCIYSEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHSDVVEYAKEKLESFIKNSDSFDKFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKILLKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGKPDSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVFVGNQLIPQPLDSEEDEKMEEDNKEEEEKDHSEAMKPEEPPQNLLREKIMKLPLPESLKAYLTYFREK
The following text describes a protein:
Function:
This protein functions as a defense against chitin containing fungal pathogens.
Sequence:
MELQSNRSLALFSVVVLVLAASCDAGGIAIYWGQNGGEGTLAETCATKNYDFVIIAFLPTFGNGQQPMINLAGHCDPSVGECTKLSTDIKSCQAEGIKVILSIGGGAGSYYLASADDARQVATYLWNNFLGGRSANRPLGDAVLDGIDFDIEGGTNLYWDVLAKSLSAYSSMGKKVYLTAAPQCPFPDAWIGNALKTGLFDYVWVQFYNNPPCQYSSSDISNLEAAWKQWTTDIPATKIFLGLPAAPAAAGSGFIPAGDLTSQVLPSIKTSSKDNENSVFVLSIFRAEATVHFVEKLVFGRGTVNKQNQQEMELQSNRPLALFSIVILVLAASCDAGGIAIYWGQNGGEGTLEETCATKNYDFVIIAFLPTFGNGQQPMINLAGHCDPSVGECTKLSTDIKSCQAEGIKVMLSIGGGAGSYYLASADDARQVATYLWNNFLGGRSTNRPLGDAVLDGIDFDIEGGTNLYWDVLAKSLSAYSSMGKKVYLTAAPQCPFPDAWIGNALKTGLFDYVWVQFYNNPPCQYSSSDISNLEAAWKQWTADIPATKIFLGLPAAPAAAGSGFIPAGDLTSQVLPSIKTSSKYGGVMLWSKYYDDQTHYSSSIKSDV
The following text describes a protein:
Function:
Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC2 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MDELQSQTEREARILARRKRIQERLAALREGDHGGGKEGENKEEIGKGKQQIIESKRRLMRVKYRTDQDVSSVRVAGDDRENQHRIQEEQTRQDLRAKLLAEAEQSARQNAAVAMRWADLFSIEVPQDLYNEIESQRQACERIIASKDKLIGEIKGELKKKDDEFVKTLKRQAEDIDTLLQYMSRQFVEVQNAYKEELDEIENAFLQERSDLLESNRREMQELFDKRSRLEQDFMDRYLAAVEAYQSQLEGHRQMDAEEYHILKIRLETDIQNLEQHLEAMRATYQLNTEKLEYNYRVLKEREKENTQTIESQKKKLSRQRDILSSLKQRYAETDRRYRDDNMKLTDEYKRITEQFKDLQSKFRHFELVDTKKYKEVWGMKEADVAALVRQLLQADKVLHEQQLGWDWRPPDDAVFAPVHGDAGSGGGAAAAATGGAAGGAAAAGGVGPNGEEESEEDAAARVREAELAERLRDGRNWGALGLLCDEAGFLIDIKARNMIERLPKDEQGQVKAEAILRSLGIADGSAFDALLEALSADSNIELRAKGMVAPQGRGMAEEKSDRGGTAVLVHPDEAVRRLKAFVEVYGTGPSRGPGGGGGGGGGMSGPMRVQGAMRRAAEREQEFWSRMTHVISDKHTRVWGALEKQLEKYLALLQERAGSLRDVESLQHQNNELRALLNQYLSSRINDELQIPPTQII
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MTRKGLRNLLQCKPFGRRHHRDSQSAAATASSSSSSSSSSLEEKVARAEVVVIKWDPESSAYAKITSLFYEDRSEARKFLAEASDLQRAMLVFVADAEPASLSHPCLVRAQTLMQAAMRRLEKEFFQILAANRDLLDPESVSVRSAYSSVSEGPDYDPWENSPEEEAHLAGKSIGEVERAAGVVMADLRAIADTMVFAGYRKECVRTYKSLRKSIVDEGLYRLGFERLAPAQIQKLDWAVLELKVRSWLVASSVAVRTLFHGERVLLDHVFAGSDAVREVVFADIAGEAALQFLGFPESVAKSKRSPEKLFRLLDLYDAVTELRPDIELIFSFDSTAAIRAQALASLSKLAEAASATLADFESAIMKESSRSTVPGGGVHPVTRNAMNYISLLADYQSALVEILADFPIQTPTAIPAFLFDTWQAPTEQQTAVSGSSSTPASSSSSEGSRRSAIAVRFAWLILSLLCKLDEKAAAYRDVGLSYLFLANNLQYIVNKVRSCRLRELLGEEWATRQAAKARQHAAGYERAAWGRVAATIPTGNVSAGEARGGMRAFNAALEEVRAAGSGWVVADAAMREEVRANVRRMILPAYRGFYTLWETAMEDAAAVLLSPDDVGNRLGELFSGSGSYRPKASSSRTV