lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Needed for flagellar regrowth and assembly.
Subcellular Localization:
Cytoplasm.
Sequence:
MVIHSKDAQPAFKRWEMTSFGDERPSVVALREAEQREIEAENARLEAEQRVQEALQAQQEQMEMGPPAPPPIAYPTVEELEAIREDARKDGYDEGHAAGHAEATEAVRKAADAALQQELQQVRVLADNFSKALQDADQLIANDVLELALQLAKGMLKNALPVKPELILPIVRDAIEYLPALQQPALLVLHPDDAPTVRAGLGEELDKGGWRVVEDPSVGRGGCKVDTASNTIDASAAARWQRLSHALGKEVDWLD
The following text describes a protein:
Function:
Probable serine protease, which plays a crucial role in the fertility of male mice including sperm migration and sperm-egg interaction.
Subcellular Localization:
[Isoform 1]: Cell membrane; Lipid-anchor, GPI-anchor. Cytoplasm, cytosol. Note=Mainly found in the membrane part of the cells and only in small amounts in the cytosol; [Isoform 2]: Cytoplasm, cytosol. Note=Present primarily in the cytosol and only in minor amounts in the membrane fraction.
Sequence:
MLLFSVLLLLSLVTGTQLGPRTPLPEAGVAILGRARGAHRPQPPHPPSPVSECGDRSIFEGRTRYSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGTNDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQPGPATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPKLTKNMLCAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEKVTQLEGRPFNAEKRRTSVKQKPMGSPVSGVPEPGSPRSWLLLCPLSHVLFRAILY
The following text describes a protein:
Function:
May function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction. May bind calcium in vitro (By similarity).
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, cilium, flagellum. Note=Localizes to fibrous sheath including the surface of the longitudinal columns and ribs of the principal piece of sperm flagella.
Sequence:
MISSKPRLVVPYGLKTLLEGVSRAILKTNPTNITQFAAVYFKELIVFREGNSSLDIKDLIKQFHQMKVEKWAEGVTVEKKECIKEPIKPPPVPCKPTHMEKSTDTEEDNVAGPLFSNKTTQFPSVHAEVQSEETSEGARGPSDKPTTPKTDYTPPSSPPPAPVSAEYAYVPADPAQFAAQMLGNVPSTYSEVLMVDVATSTPAVPQDVLSAEFAEEVVLSAPLVCSGETVEVQVVSKTSAQVVVGPVSEAEPPKASSAPLQGEQEPPAHEAPDTQVTSASRISSIYNDVPVNEGVVYVEEIPGYIVIPFTDHDQVACVKEIEQSPPGSPKAVEPKTKISIESLKTVQVEENSQHKSSVHVEAEATVLLSNTALDGQPEVPAEPLDAEGFFKVASENSLHLETEIVIINPDDPGQEESGGNAAPHSSGDPFPPAPGGLTEPEMQPDGEAAPEQV
The following text describes a protein:
Function:
Required for cuticle shedding and normal alae morphology and localization, and subsequently larval development.
Subcellular Localization:
Cytoplasmic vesicle. Secreted. Secreted, extracellular space, extracellular matrix. Note=Secreted by the underlying hypodermis.
Sequence:
MRRLSAILPILLLSNFWPTVESLNYKCHNDQILVVQSFGNDTIRMHCQRLDLCGYQKLKCDYDELQPQCGGKLNFVSHVNQKGSTAPVEHTCCNLFNPRSHHSIPTHIGNDCFIYELPDGSSNGKKVDPAPADDAPYAVLKNPAEIPEQFDGVTGYRLRLFLLKNKSPPTLLVKGIERRLDGYRVTICRPRCTSYDKVVNDNEGAEDGEWKAISWSSWSSSSWSTWARHAFNKAAAEGGEAAERIRTRMPIGEKTVAGAAGATGAAGSDKSNINIHVESNGNNNNSFEGGRSSSEKSDGQLNREISGSSEAGAGGKGGAGADGAAGSGAGAGAGAGTNGNINITVHTDGKSGGNAVAVANANVTVNGAGGVSTTGTGAQTGNESGLGGSAGTDKAGGKKGGHGDSGDSGNNKNKDNGKGKGKGKNDEEDEEDNGDEDGNGKGGNGGNPKGEWDDGDGDEDDDGTDGGSKESGNNGKGKGKGSGDGDGNRNGNGDGNGRPKGDGNIKINIHSPDDNDLLEKDENGPNGKGGAGNGNGDGDKDNNGKGNGTGDGDGDGNGNGNGLTGDGNGTGDGDNNESGNGNGDGSDKNSGAGAGTKPENREGGDGNGNGTGDGNGDGNDNGNGSKGLGTGSGDGKGEGNKSGTPGKSDGKEDGAGSNGSGNGKEGDGNKSGGSGKGGAGNGKSGDGSGDGKNNGNGGTGDGKDKNGKGSGSGDNDKSGTRAAGKGNAEGNGKGNGNDGKGSGSGDGSGAGGKGDKSDSESGNEADGKDGKKNEGAGGEAAAGSGGANKGGSDGDDDDVDVTDVEVGTKPLTGTKLEELLAKLPNETADGNATGDGNEFGTVQTGAKHNAESSASGIPLVQARSNTVNGGAPVPPAPGSGATGSGTSGSGTSESVTNGSGATESGSTGSGTTGTGTSGTGSSGTGASAARTSSIAGDAPQAAVLADTPGAAGAAGGGRSNCFSADSLVTTVTGQKRMDELQIGDYVLVPSSGNVLKYEKVEMFYHREPKTRTNFVVLYTKSGRKLSLTGRHLLPVAECSQVEQYTMNPDGIDVAMRESKYAEKARKGECVLSIDESGEVIADEIVRVGRMTNVGIYSPMTVEGSLIVDGVLSSCFSHLESHSAHKLIFDFIYYVYNAFGLLNTNHVDLQPIPTFVSFAQYLSKTVLPFS
The following text describes a protein:
Function:
Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is essential for virulence in a mouse model of acute infection.
Subcellular Localization:
Cell membrane; Lipid-anchor.
Sequence:
MPKVGIAAQAGRTRVRRAWLTALMMTAVMIGAVACGSGRGPAPIKVIADKGTPFADLLVPKLTASVTDGAVGVTVDAPVSVTAADGVLAAVTMVNDNGRPVAGRLSPDGLRWSTTEQLGYNRRYTLNATALGLGGAATRQLTFQTSSPAHLTMPYVMPGDGEVVGVGEPVAIRFDENIADRGAAEKAIKITTNPPVEGAFYWLNNREVRWRPEHFWKPGTAVDVAVNTYGVDLGEGMFGEDNVQTHFTIGDEVIATADDNTKILTVRVNGEVVKSMPTSMGKDSTPTANGIYIVGSRYKHIIMDSSTYGVPVNSPNGYRTDVDWATQISYSGVFVHSAPWSVGAQGHTNTSHGCLNVSPSNAQWFYDHVKRGDIVEVVNTVGGTLPGIDGLGDWNIPWDQWRAGNAKA
The following text describes a protein:
Function:
Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAATCEISNVFSNYFNAMYSSEDPTLAPAPLTTFGTEDFVLTLNNQHMSPEGPVGCVGPQTRSQRDRTEPPAVLHLAEKASWTGERPQFWSKTQVLDWISYQVEKNKYDASSIDFSRCDMDGATLCNCALEELRLVFGPLGDQLHAQLRDLTSSSSDELSWIIELLEKDGMTFQEGLGDSGPFDQGSPFAQELLDDGRQASPYYGSSYGPGAPSPGSSDFSTSGTDTPQSSHSSDSGGSDVDLDLTDSKVFPRDGFPDYKKGEPKHGKRKRGRPRKLSKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSGWKEEEVGESQN
The following text describes a protein:
Function:
3' to 5' exoribonuclease required for proper 3' end maturation of MRP RNA and of the U5L snRNA.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MFSPLGQFKHIVCPFLRTGRKCQSRNCFFSHDFQNSTKISPPYSENVEGYPKVKIEKSLPYKYDNCKLSICVPIVTTCIPYHSVENLNFNIRQNISTTLNLEKTNDSIKETKNENFRMDVLETYKCKQLNHQTTHLPTNTVLKKRSLFNDAISIVPNKKKQLVSAISTNSDSQGASSNIIPTPKYDSNSPAGHELRKRMTHLLYESYKDLGYSNAESSMLALLDEKNICETANSKMIYSSSCKSKILSLKKAPKKNEIQGSTPDEKLESLVHSEEELILWGYNIGDVAPVNPPDELRECDRCGTRFADPRGPCTYHWGKLFREKQGGEKIRTYTCCGVKEGDSSGCIIEDNHVFKYRHLPYLASVHPFSYLPDSTNSKQLSHCALDCELCYTTNGMELARLTVVAKESIIMDVFIKPKGKILSLNTRFSGIHDAKELESGITMDQMYIKIKELGMNKNTILIGHGLENDLNAMRLIHKRVIDTALLFTHARGPPFRYSLKYLTKKYLGTTIQTSTHDSEEDAVSALQLVFYKTKSNESQN
The following text describes a protein:
Function:
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSTPGVNASTSLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAATAVTSVVSRGHPAASPGLPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSGQHCSDSRRTSSAMSGHSRSFFSRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPGMGLAQKDTTSLRTLRISETSDSSQGQDSESVLLVDEVGGSGRAGPAPKGSSLQVTFPSETLNLSEKCI
The following text describes a protein:
Function:
Effector protease that disrupts necroptosis in host cells by mediating proteolytic cleavage of host RIPK1 and RIPK3.
Subcellular Localization:
Secreted. Note=Secreted via the type III secretion system (T3SS).
Sequence:
MPSVNLIPSRKICLQNMINKDNVSVETIQSLLHSKQLPYFSDKRSFLLNLNCQVTDHSGRLIVCRHLASYWIAQFNKSSGHVDYHHFAFPDEIKNYVSVSEEEKAINVPAIIYFVENGSWGDIIFYIFNEMIFHSEKSRALEISTSNHNMALGLKIKETKNGGDFVIQLYDPNHTATHLRAEFNKFNLAKIKKLTVDNFLDEKHQKCYGLISDGMSIFVDRHTPTSMSSIIRWPDNLLHPKVIYHAMRMGLTELIQKVTRVVQLSDLSDNTLELLLAAKNDDGLSGLLLALQNGHSDTILAYGELLETSGLNLDKTVELLTAEGMGGRISGLSQALQNGHAETIKTYGRLLKKRAINIEYNKLKNLLTAYYYDEVHRQIPGLMFALQNGHADAIRAYGELILSPPLLNSEDIVNLLASRRYDNVPGLLLALNNGQADAILAYGDILNEAKLNLDKKAELLEAKDSNGLSGLFVALHNGCVETIIAYGKILHTADLTPHQASKLLAAEGPNGVSGLIIAFQNRNFEAIKTYMGIIKNENITPEEIAEHLDKKNGSDFLEIMKNIKS
The following text describes a protein:
Function:
Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSLWLEHFLTGYFQLCGLVCGWSGSRLGRLLSSTFLVLILIELVGEIETYFTEENPDNESVPAYFAKVIMGVNMAYKMIHAWIALSALFECRRFRYLLEELPPVKATSFIYRHLILEIILFACNAFLVLSEYTIRGIYLENLRYAYSLQAVRARYLQMMVLVDRLDGKLEQLHHRVISGSSDYKTLRLDYAHLAKVTRSLSHLFGLSLLLLNVLCLGDWIIVCNVYFMVAYLQVLPATLFLFGQVMFVVCPTLIKIWSICAASHRCVSKSKHLQQQLKDLPGQTPVERSQIEGFALQIMQDPIQIDVCGIYHLNLQTLAGMFFFILEALVIFLQFVSLVRT
The following text describes a protein:
Function:
Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: There is no evidence for the expression of the corresponding protein in vitro.
Subcellular Localization:
Apical cell membrane; Multi-pass membrane protein. Cell junction. Note=Localizes to the apical membrane of epithelial cells. Localizes on internal membrane structures under resting conditions, translocates to the plasma membrane and cell-cell junctions upon challenge with enteric pathogens.
Sequence:
MLPTSLKTLVLLGALLTGPLGPAGGQDAPSLPREVQRYDGWFNNLKYHQRGAAGSQLRRLVPANYADGVYQALQEPLLPNARLLSDAVSKGKAGLPSAHNRTVLGLFFGYHVLSDLVSVETPGCPAEFLNIYIPRGDPVFDPDKRGNVVLPFQRSRWDRSTGQSPSNPRDLTNQVTGWLDGSAIYGSSHSWSDTLRSFSGGQLASGPDPAFPRNSQNSLLMWMAPDPATGQGGPQGLYAFGAQRGNREPFLQALGLLWFRYHNLCAKRLAQEHPHWGDEELFQHARKRVIATYQNIALYQWLPSFLQKTPPEYSGYRPFMDPSISPEFVAASEQFLSTMVPPGVYMRNSSCHFREFPKEGSSSSPALRVCNNYWIRENPSLKTAQDVDQLLLGMASQISELEDRIVIEDLRDYWPGPDRYSRTDYVASSIQSGRDMGLPSYSQALQALGLEPPKNWSALNPKVDPQVLEATAALYNQDLSRLELFLGGLLESHGDPGPLFSNIILDQFVRLRDGDRYWFENTRNGLFSKEEIAEIRNTTLRDVLVAVSNVDPSALQPNVFFWQEGAPCPQPQQLTTEGLPQCVPVTVIDYFEGSGAGYGVTLLAVCCFPVVSLIIAWVVARFRNRERKMLLKKGKESLKKQTASDGVPAMEWPGPKESSYPVTVQLLPDRSLKVLDKRLTVLRTIQLQPTQQVNLILSSSHGRRTLLLKIPKEYDLVLMFNSEEDRDAFVQLLQDLCVCSTPGLRIAEMDEKELLRKAVTKQQRAGILEIFFRQLFAQVLDINQADAGTLPLDSSQQVREALTCELSRAEFADSLGLKPQDMFVESMFSLADKDGNGYISFREFLDILVVFMKGSPQDKSRLMFTMYDLDGNGFLSKEEFFTMMRSFIEISNNCLSKDQLAEVVESMFRESGFQDKEELTWEDFHFMLRDHDSDLRFTQLCVKGGAGGTGDIFKQSNACRVSFLTRTPGNRVMAPSPRLYTEALQEKMQRGFLAQKLKQFKRFVENYRRHIVCVTIFSAICAGLFADRAYYYGFASPPTDIEETTYVGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYIPFDAAVDFHRWIAMAAVVLAVVHSLGHAVNVYIFSVSPLSLMTCVFPSVFVNDGSKLPPKYYWWFFETVPGMTGVLLLLVLAIMYVFASHHFRRHSFRGFWLTHHLYVVLYALIIIHGSYALIQLPSFHIYFLVPAIIYVGDKLVSLSRKKVEISVVKVELLPSGVTYLQFQRPKTFEYKSGQWVRIACLSLGTNEYHPFTLTSAPHEDTLSLHIRAVGPWTTRLREIYSPPVGGTSARYPKLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFKSSMGTQMLCKKIYFIWVTRTQRQFEWLADIIREVEENGSRDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSVTHFGRPPFELFLDSLQEVHPQVHKIGVFSCGPPGMTKNVEKACQLINRQDRAHFVHHYENF
The following text describes a protein:
Function:
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
Subcellular Localization:
Cytoplasm.
Sequence:
MAKTIFYFSYRKTEELHAKAKELKKITTDYGYELTDDYQKANVIISIGGDGAFLKSVRETGFRQDCLYAGIALTEQLGQYCDFHINQLDEIIKAAIEDRWLVRRYPTIYGTVNNTKAFYVLNEFNIRSSIIRTLTMDLYINDSHFETFRGDGMVISTPTGSTAYNKSVNGSIVDPLLPSMQVSELASINNNKFRTLGSSFILSPKRKLRIEIASEEGNNEFPMIGMDSEALSIQHVHEVNLEVGDRFINIIKLPKNSFWDKVKRNFL
The following text describes a protein:
Function:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Sequence:
MGIALCKPERDAAAKNRQIETQIRIENQANKRKIKMLLLGISDSGKSTIVKQMRVNYCNGFNETEVVNAIFLIRNNIIDAFKHISLLILDSHIIKSDTEKVLLKLFAFESQKIEMMQEVDELRLINSIRVLECISVFFEHYSYHPMIPDNIHYFFPHLERIAISEYMPTVEDLIHMRQTTLGVHEISFDYQTQTIRLIDVGGQKTERRKWIHFFEGVTAVMFVCSLSSFNQATEQEPNNAFAWETSLNKVQNKILVRSTGKAKQRPGMVNRLDESVDLFTSIRENNFLKSSNFMLFLNKIDLLGKKLETIQFVNHFPAYEQWITNDNSVQSVAEFIESMFREGLDADQKIYAHLTQATITTNIEYTFGLCCDVIFNKNIETLSLE
The following text describes a protein:
Function:
Has a glutathione transferase activity with ethacrynic acid and nitrophenyl acetate. Has low glutathione peroxidase activity with cumene hydroperoxide.
Subcellular Localization:
Cytoplasm.
Sequence:
MATAKPILYGAWISSCSHRVRIALNLKGVDYEYKAVNPRTDPDYEKINPIKYIPALVDGDFVLSDSLAIMLYLEDKYPQHPLVPKDIKTKGLDLQIANIVCSSIQPLQGYGVIGLHEGRLSPDESLEVVQRYIDKGFRAIEKLLDGCDSKYCVGDEVHLGDVCLAPQIHAAINRFQIDMTKYPILSRLHDAYMKIPAFQAALPQNQPDAPSAK
The following text describes a protein:
Function:
Intramembrane glycolipid transporter that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. RFT1 could mediate the translocation of the cytosolically oriented intermediate DolPP-GlcNAc2Man5, produced by ALG11, into the ER lumen where dolichol-linked oligosaccharides assembly continues. However, the intramembrane lipid transporter activity could not be confirmed in vitro.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MNCPQQTVGGALRGIASSVLFQLLQRSITFISNVIVIRSVGEEVTGFFHVHLQLLMNIVYFLSREFSRRTIMRKYTDNLSKGISFSLITIIVGLIINIIALPILYYQAPEMKYALLSYCIHSIGLFLELIQEPYLVYMLLTQKHIFRIYCELPSIFIRMILQAILISLYPKYALIIQPTLFALSSLTIFISYHHSIKLPQIDIQMISFKSLKSHSDNLWLFGRQTIQKFLLQEGEKAVLIVTTTLTIQGIFSVISNISSLVVRFLFLPIEDVSYSLFSKIRQNKDELLNAFCSFLKIILHLSLLILVFGPPYSKALLDFLYKNEEFTNNSYLLIIAFITISTIAINGISESFFHATATDEQLNTSNNLMFLFSIIYVSLCIVLSKLFGPSGLFISNIISMILRAFYSHYNIYQLYGYLPWKKCTPTKLTLVSLFVVFGINTYISYIFSTQSFICLILGVCLGFIELLVIWLCDKPFITSLKMFWNERKSSSPYDN
The following text describes a protein:
Function:
Component of the GSH degradosomal complex involved in the degradation of glutathione (GSH) and other peptides containing a gamma-glu-X bond.
Miscellaneous:
MISCELLANEOUS: Present with 1940 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MYDSRGVALHSELIHRWNHAFSILSIVAFPKKRLLFAGSQDSKILVFDLPTYNLIHTIRLGESQEETHTRSSVLCLTGSEDENFLFSGGADSLVRIWSIGEKTIRDDFLPVTEIATVYSVTDIGDIFSLAYLDSLETIVFGCQNASLLYVENLIQKIEKKSSDGVENINKLPHRRYDKFFDSLGPTGYSSNSLSQTSLTSLQENCGAAIIEVPSENIIKYAHYGFIYSINKLCPRFNQLLEKSSRTSGAEHIISSAGDGISKLWEFSKDKGQNTVKISLINDKIDNEDSVISQTIEFPFLYCGLTDGIIKIWDLNTQQIISTLKTKHESDVISISVYMDHVFAIDESGITHFYQNQVNHWNPQQGKILSSEIFSKSNAGSVSLLTGGSDGSLTLWDITSLLSAVPLSSNSPINASSTLQTTNLWAAYQSASLNNEEMLNTLRELISFQTVSQSKDTTNTLSLRRCAIYLQQLFLKFGATNSQLFPLPDGGNPVVFAYFQGNGKVSQVKGAKKKRILWYGHYDVISSGNTFNWNTDPFTLTCENGYLKGRGVSDNKGPLVSAIHSVAYLFQQGELVNDVVFLVEGSEEIGSASLKQVCEKYHDIIGKDIDWILLSNSTWVDQEHPCLNYGLRGVINAQIKVWSDKPDGHSGLNGGVYDEPMVNLVKIVSKLQNEQNEIMIPNFYSPLKDLTEEEYQRFQKITELANIDENTTVQDLITNWTKPSLSMTTVKFSGPGNITVIPKSVTMGISIRLVPEQSVEQVKRDLKAYLEESFKQLKSQNHLEIKVLNEAEGWLGDPTNHAYQILKDEITTAWDVEPLLVREGGSISCLRMLERIFDAPAVQIPCGQSTDNGHLANENLRIKNWSNLTEILSKVFNRL
The following text describes a protein:
Function:
Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MENSYTVDGHRLQYSVPLSSMHETSQNSETYGLSKESPLVCMPLFETNTTSFDISSLFSFNPKPEPENTHRVMDDSIAAVVGENVLFGDKNKVSDHLTKEGGVKRGRKMPQKTGGFMGVRKRPWGRWSAEIRDRIGRCRHWLGTFDTAEEAARAYDAAARRLRGTKAKTNFVIPPLFPKEIAQAQEDNRMRQKQKKKKKKKVSVRKCVKVTSVAQLFDDANFINSSSIKGNVISSIDNLEKMGLELDLSLGLLSRK
The following text describes a protein:
Function:
Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MEFSVKSGSPEKQRSACIVVGVYEPRRLSGIAEQLDKISEGYISNLLRRGDLEGKPGQMLLLHHVPNVLSERVLLVGCGKERELDERQYKQIITKTINTLNETGSMEAVCFLTELHVKGRDTYWKVRQAVETTNSSLYCFDALKTRKGETRRPLRKLVFNVPTRRELTLGERAIEHGMAVSSGMHLCRDVANMPPNICNPAYLASQARQLAEIHENLHVSTVGEEQMAKLGMNSYLAVGRASANESIMTVMEYKGAVDSTEKPIVLIGKGLTFDSGGISLKPGEAMDEMKYDMGGAAGVIGTMKAICEMKLPINVVGILAGCENMPSGNAYRPGDILTTLSGQTVEVLNTDAEGRLVLCDVLTYVERFDPELVIDTATLTGACVIALGKHASGLFSSHNPLAHELLNAGEQSGDRAWRMPLWDEYQDMLDSPFADMTNLGGRPAGAITAACFLSRFAKKYNWAHLDVAGTAWNSGANKGSTGRPVPILTQFLINRAGVELGE
The following text describes a protein:
Function:
Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
Miscellaneous:
MISCELLANEOUS: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
Subcellular Localization:
Nucleus.
Sequence:
MKPGQTCDDCQQIKTSDWSYGRPQSNSSLENFKSCKLITQWTKNGVFAISAIKRNAPSKDAGRDSKIAAKVEKWSIESVCKYGRSLDFTSNEPNAASVIKTLFKEIHGSVLSKLNIHPLHWDECADSELGPFLKTFNNSVKVFRKNNPRDVLLSKENWRQKEASEFRVICDLACQLAIPNPRVLNTYYAGFSSGTYGETNIETLQKILDLLGVKEDDVFIDLGSGIGQLVTFAAAYTNIAHVRSIELQQVPAGFADENARQFKKLMRHFGEKPRPFELELGDFNTEETETFLKEKATIIFCNNLAFDPGLMIKLRAILQFCNNGTKIVVTQKLETTKKGRTPRDYLWRNELRTVPGHSGPD
The following text describes a protein:
Function:
Myoblast-specific protein that mediates myoblast fusion, an essential step for the formation of multi-nucleated muscle fibers. Actively participates in the membrane fusion reaction by mediating the mixing of cell membrane lipids (hemifusion) upstream of MYMX. Acts independently of MYMX (By similarity). Involved in skeletal muscle regeneration in response to injury by mediating the fusion of satellite cells, a population of muscle stem cells, with injured myofibers (By similarity). Also involved in skeletal muscle hypertrophy, probably by mediating the fusion of satellite cells with myofibers (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Localizes on the plasma membrane of myoblasts, where it mediates myoblasts fusion. Also localizes in the Golgi apparatus and post-Golgi following palmitoylation; the role of Golgi localization is unclear.
Sequence:
MGTLVAKLLLPTLSSLAFLPTVSIAAKRRFHMEAMVYLFTLFFVALHHACNGPGLSVLCFMRHDILEYFSVYGTALSMWVSLMALADFDEPKRSTFVMFGVLTIAVRIYHDRWGYGVYSGPIGTAILIIAAKWLQKMKEKKGLYPDKSVYTQQIGPGLCFGALALMLRFFFEDWDYTYVHSFYHCALAMSFVLLLPKVNKKAGSPGTPAKLDCSTLCCACV
The following text describes a protein:
Function:
Catalyzes the stereospecific oxidation of D-lactate to pyruvate. Involved in the detoxification of methylglyoxal and D-lactate, but probably not involved in the metabolization of glycolate.
Subcellular Localization:
Mitochondrion.
Sequence:
MAFASKFARSKTILSFLRPCRQLHSTPKSTGDVTVLSPVKGRRRLPTCWSSSLFPLAIAASATSFAYLNLSNPSISESSSALDSRDITVGGKDSTEAVVKGEYKQVPKELISQLKTILEDNLTTDYDERYFHGKPQNSFHKAVNIPDVVVFPRSEEEVSKILKSCNEYKVPIVPYGGATSIEGHTLAPKGGVCIDMSLMKRVKALHVEDMDVIVEPGIGWLELNEYLEEYGLFFPLDPGPGASIGGMCATRCSGSLAVRYGTMRDNVISLKVVLPNGDVVKTASRARKSAAGYDLTRLIIGSEGTLGVITEITLRLQKIPQHSVVAVCNFPTVKDAADVAIATMMSGIQVSRVELLDEVQIRAINMANGKNLTEAPTLMFEFIGTEAYTREQTQIVQQIASKHNGSDFMFAEEPEAKKELWKIRKEALWACYAMAPGHEAMITDVCVPLSHLAELISRSKKELDASSLLCTVIAHAGDGNFHTCIMFDPSSEEQRREAERLNHFMVHSALSMDGTCTGEHGVGTGKMKYLEKELGIEALQTMKRIKKTLDPNDIMNPGKLIPPHVCF
The following text describes a protein:
Function:
Plays an essential role in chain termination during de novo fatty acid synthesis.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MASSTPEEISSVKNSITSKGLNRALKVLSALASSLKDRSPSRTKKQCFTIRSYEVGANKTATVETMMSLLQEFAVNHMSRTDGFSKDGIWTSPSMRRNSVTWVVAFIHLKIDTYPSWNDIVEIETWTRALGDRLGMHGDWLIKDQNTRSILARATSTWLMINTETRRFSKIPYEVWNEIMPFFNEESRALGEDGDPLDDIEEIVASQAEYVRSDLRAHHNDLDMNQHVNNSRYFRWLLEAVPPSVLKSHELARVTLEFKRECREAQPVRSLCRLKSQTPTGVEFVHRLLLQDRGSEVLRGQTLWRATNKAKI
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase able to catalyze polyubiquitination with ubiquitin-conjugating enzyme E2 UBC8, UBC10, UBC11, and UBC34 in vitro.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Domain:
The RING-type zinc finger domain mediates binding to an E2 ubiquitin-conjugating enzyme.
Sequence:
MSFIDPRTYIPSNSTESQILKFTFIVCVPICVILIVLLVLYIMRRNSNTNVDWSSLGGFVPTNNNLSTAELGLSKDIREMLPIVIYKESFTVNDTQCSVCLGDYQAEEKLQQMPSCGHTFHMECIDLWLTSHTTCPLCRLSLIPKPSVDLSHQSIEIVSSIENTNGGEASTQPDSQSATEAIIHIDDVEEGNRDSIEVVKESEENDRNSVGTSDGCCSCRLGEKA
The following text describes a protein:
Function:
Plays a role in determining ER morphology.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Domain:
The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.
Sequence:
MGSFIGILKKNKSSKEILEDIEEKIKNNESTKRLYDHRLKNVTFDLVAVVLPLYITSLIGYYYLYLPEQTPDKIIYSLPFAVVPFGAYGIKKFLEYWYKKAIGKSNLTLRELQDSKKKVLEEVMEKETYKTAKEILERFDPASKKLQMFNQEANNTDIRRRGNAATKAKKKPDDGANNSVVLADVALRQQQQLLYQEKIIKEQHLKLQKQNDQISQGSKLLQSKKSNDSKNTTSTSENIESSINAANETVKQAEGDDDDYLLLLPGTATDGNKEPVSYPILPKDRSMTDKIMEYFVGDGPTNRYALICSNCAGHNGMALKEEFEYTTFRCAYCRYLNPSRKRRQSAPPLNVSLSESVPTSTLASDTKNTLSTPSSKRKVIHTSTPKVKETKPPDVGPKASESTSLAAVTEESTIRNEDESSNES
The following text describes a protein:
Function:
May transport inorganic phosphate (Pi).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKFGKEFASQMVPEWQEAYMDYDYLKTLLKELQRFKHRTKPPAAPSLKRKLTLYRAFSGLTQTHHHHNPTSPSSSPDDIESQPILVNSVSRDGSQSYETTFLMSSEEGGEYELVYFRRLDDEFNKVDKFYRAKAQEVMKEADVLNKQMDALIAFRIKVENPPGIHFDRSVEMTRLASDIAASAAALSASTPSGAKSASKRAAHLEAIEESTHGQADDDDNGDEKERNTPTLEAKPAKPKPKVIVPAPLEILDRVKMNNTLETPRSTIKGVLKVPNHTDLSFSRENLRKVEEQLKRAFVEFYQKLRLLKSFSFLNTLAFSKIMKKYDKITSRSASKSYMKMVDNSYLGSSEEVTKLMERVETTFIKHFSNANRSKGMSILRPKVKRERHRTTFSTGFFAGCAASLLLALILMIRARNIMDSEGRTQYMETMFPLYSLFGFIVLHMLMYAINIFYWRKYRVNYAFIFGFKPGTELGYRQVLLVSFGLGALALASVLANLDMEMDPKTKDYKAFTELVPLMLVVFIFIVLFLPFNVLYRSSRFFLLTCLFHCICAPLYKVTLPDFFLADQLTSQVQAIRSLEFYVCYYGWGDFKRRENTCRDSNVYNTFYFVVAVLPYLARLLQCLRRLFEEKDAMQGLNGLKYFLTIAAVCLRTAYSLNKGIAWRIIAWIVSAIAAIFCTYWDLVYDWGLLNRHSKNRWLRDKLLVPHKKVYFGAMGLNILLRFAWLQTVLNFQLPLHPQTLTTIVASLEIIRRGIWNFFRLENEHLNNVGKYRAFKSVPLPFNYDEDDDKDD
The following text describes a protein:
Function:
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.
Subcellular Localization:
Nucleus.
Sequence:
MTARIASARFRQRKLSTKQNLPIVREHEVEQLADDDASRHIPKVETGVEKGEEIAVISAAQASSTGGKIAQLFIPTPDAVASQLQYDDLYQKVFRQPATYIRFSSTVEDTSGCPYCMTSDDAAFLKSFNQKQGKKAHCSEDEFEEIMYFFEEKTQEKQPYADVDNTPVLPFEELEADFDETISESARRFAKEVYVHWKNQRLLKGNRPLLPSLKFEKNLETDDADPYVCFRRREVRQVRKTRGRDAQVNDKLKKLRKDLEDARLLMSHVRRREVLQREQIQIDKTIFEQRAAVKEIKRKLSIKGDDEELLITQKPAPKPKRPADLERVRQNIPGMKPRDTRSDGRLVDGDLVYLEEQQTKKTEAIESFIEDNLVKHQKWNVGWVDATWRPITPPLELPAAKSDFRTVFTQSQLPTPPASVSDEGGADAMTVDRVNKQDEPRRSARIRFATPPEDVPFQDQTRFRRRIGRGGRVMIDRRGMKRQKIENGEVDERVADRWKFSGDSSEDEQIYAVDWTDTMHIRYRNMIDRQGEKQQPQQVAPNPNRRSIENHNRSASGHLMPPTPTNASAG