lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Glycosyltransferase which regulates the biosynthesis of heparan sulfate (HS). Initiates HS synthesis by transferring the first N-acetyl-alpha-D-glucosamine (alpha-GlcNAc) residue (GlcNAcT-I activity) to the tetrasaccharide linker (GlcA-Gal-Gal-Xyl-)Ser core linker. May also transfer alpha-GlcNAc residues during HS elongation (GlcNAcT-II activity). Lacks glucuronyl transferase II (GlcAT-II) activity. Important for both skeletal development and hematopoiesis, through the formation of HS proteoglycans (HSPGs). Through the synthesis of HS, regulates postnatal pancreatic islet maturation and insulin secretion; Receptor for REG3A, REG3B and REG3G, induces the activation of downstream signaling pathways such as PI3K-AKT or RAS-RAF-MEK-ERK signaling pathway. Required for the function of REG3A in regulating keratinocyte proliferation and differentiation. Required for the inhibition of skin inflammation mediated by REG3A through the activation of PI3K-AKT-STAT3 pathway. Required for the function of REG3A and REG3G in glucose tolerance in pancreas. Expressed in microglia, is activated by nociceptor-derived REG3G in response to endotoxins, leading to the inhibition of kynurenine pathway to prevent endotoxic death.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus.
Sequence:
MTGYTMLRNGGVGNGGQPWMLRWSSRIRLTWLSFTLFIILVFFPLIAHYYLTTIDDADDAGKRIFGPRTGNELCEVKHVQDLCRIRESVSEELLQLEAKRQELNSEIAKLNLKIEACKKSIENAKQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPDKDETNFPLPKSNRNCRLHNCFDYSRCPLTSGFPVYVYNSDQFSFGNSLDPLIKQAFESTVRTNVYVTENANIACIYIILVGEMQEPVTPKPTEIEQQLHTLPYWRTDGHNHLIINLSRKSETQNFLYNISTGRAMIAQSTFYDVQYRPGFDIVVSPLVHAMSEPNFLEIPPQVPVKRKYLFSFQGEKVESLRSSLQEVRSFEEEMEGNAPADYDDRIIATLKAVQDSKLDFVLVEFTCKNQPKPSLPTEWALCGEREDRLELLKLSTFALIITPGDTHLVISSGCAMRLFEALEVGAIPVILGEQVHLPYHNVIRWNEAALIIPKPRITEVHFLLRSISDNDLLAMRRQGRFLWETYFSTSDSVFSTVLAIIRTRIQIPAVPIREETAVEIPHRSGKAAGTDPNMADNGDLDLGPVETEPPYSSPKYLRNFTLTAMDIYRNWNAAPGPFHLFPHTPFDPVLPSEAKFLGSGTGFRPIGGGAGGSGKEFQAALGGNVPREQFTVVMLTYEREEVLMNSLERLNGLPYLNKVVVVWNSPKLPSEDLLWPDIGVPIVVVRTEKNSLNNRFLPWDEIETEAILSIDDDAHLRHDEIMFGFRVWREARDRIVGFPGRYHAWDIPHQSWLYNSNYSCELSMVLTGAAFFHKYYAYLYSYVMPQAIRDMVDEYINCEDIAMNFLVSHITRKPPIKVTSRWTFRCPGCPQALSHDDSHFHERHKCINFFVKVYGYMPLLYTQFRVDSVLFKTRLPHDKTKCFKFI
The following text describes a protein:
Function:
Putative OTU-type deubiquitinase. Catalytically inactive towards all diubiquitin molecules and long K48- and K63- linked ubiquitin chains in vitro. Potential modulator of apoptosis.
Sequence:
MSEVLQRLASTEVRKARDPIDRFLERRQLFRKHMLGDASSLFRVVAEQVYDTQMLHYEVRMECVRYMFTKWKTFRRFVSGDFDEYLWHLGKTKTAGTILELGAMCHLYRRNVIIYEPFDMGRMVTYNKDYKEILRIFMNSMGHFETVLTMQDVDMAAVCQSVSFKMLYKHLFRLPDVDLAVEWMLYPDTFKMGTEYEFDSRGRAIRLLCRNGRSFKLDRPESTICLLENSQMCPFHNRRLAMGGQFADFSCMRILLEENNIPFSYLVAKSMDPCRYRNVELTSAIEARREAYEFGIYIGDYNFKVGAKCQVQLDTNRRDLLSACYIQSIDKKKSVCKVFIEEQGKLVDVPSDNLHPLPPDEFKAWDFARKRPQRLHNSQMGRQSVQGDQQGFVPDPMPGTAPSMPPPPVADPRPVNVTAQQPPVFGPSRWMEPTRPLMPNPLMIHQTGSFVFVQQPRVGPPSVMMHVLIIVHNAPYMLAFDHAPHPPAPQCTAPF
The following text describes a protein:
Function:
Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.
Sequence:
MSTRKASTDVHEFEGMFLGFHVHFKVTSVIGHVFRLIFLPKLSPLKSSNPSQMLNCQCYLLRAMTDSHPWFCVQRYLQINTFKPEKFWAVRPYIIQKGYELQLEWERNKLFDYDVAVMFQKLVMEDGILEVTEMVEKQESKSRPFGLNTVNLLKVASSALSYPRTESTAYPSSFDFRGTLRAQVNNPTWASYVQRLLADGYQKPRSGTDVGDHPPVTPLRSATEDMLGNDAGRLYEYICTHFIGTVSPDCKYVR
The following text describes a protein:
Function:
Synthesis of fructose 2,6-bisphosphate.
Miscellaneous:
MISCELLANEOUS: Present with 1710 molecules/cell in log phase SD medium.
Sequence:
MFKPVDFSETSPVPPDIDLAPTQSPHHVAPSQDSSYDLLSRSSDDKIDAEKGPHDELSKHLPLFQKRPLSDTPISSNWNSPGITEENTPSDSPENSATNLKSLHRLHINDETQLKNAKIPTNDTTDYMPPSDGANEVTRIDLKDIKSPTRHHKRRPTTIDVPGLTKSKTSPDGLISKEDSGSKLVIVMVGLPATGKSFITNKLSRFLNYSLYYCKVFNVGNTRRKFAKEHGLKDQDSKFFEPKNADSTRLRDKWAMDTLDELLDYLLEGSGSVGIFDATNTSRERRKNVLARIRKRSPHLKVLFLESVCSDHALVQKNIRLKLFGPDYKGKDPESSLKDFKSRLANYLKAYEPIEDDENLQYIKMIDVGKKVIAYNIQGFLASQTVYYLLNFNLADRQIWITRSGESEDNVSGRIGGNSHLTPRGLRFAKSLPKFIARQREIFYQNLMQQKKNNENTDGNIYNDFFVWTSMRARTIGTAQYFNEDDYPIKQMKMLDELSAGDYDGMTYPEIKNNFPEEFEKRQKDKLRYRYPGIGGESYMDVINRLRPVITELERIEDNVLIITHRVVARALLGYFMNLSMGIIANLDVPLHCVYCLEPKPYGITWSLWEYDEASDSFSKVPQTDLNTTRVKEVGLVYNERRYSVIPTAPPSARSSFASDFLSRKRSNPTSASSSQSELSEQPKNSVSAQTGSNNTTLIGSNFNIKNENGDSRIPLSAPLMATNTSNNILDGGGTSISIHRPRVVPNQNNVNPLLANNNKAASNVPNVKKSAATPRQIFEIDKVDEKLSMLKNKSFLLHGKDYPNNADNNDNEDIRAKTMNRSQSHV
The following text describes a protein:
Function:
Transcription factor that plays a crucial role in external sensory organ (ESO) that elaborates from a single precursor cell (ESOP cell). Mediates the differentiation of lineage branch that generates the internal 'ES' and 'th' cells (external sensory neuron and thecogen cells, respectively) from the IIIB cell. Its absence leads to re-specification of IIIB daughter cells into external tormagen cells (tr cells), or internal multidendritic neurons (MD cells). One of its role in the development of the ESO lineage is to modulate the activity of Notch and PAX2 signals.
Miscellaneous:
MISCELLANEOUS: Was named 'hamlet' because of its 'to be or not to be' role in ESOP cells differentiation.
Subcellular Localization:
Nucleus.
Sequence:
MDAFFKDRAQAEHILQEWVRRREPVCELDIRDSGGVYAKTPLQRGTRYGPFPMKLSHQPNDPQLAWKAHSRHYNGWLEPTEDVSTWLKKIRSVQDDCIGEANLQSYINAGYLWYETNRYVNAGSEMVVDGRPKSPVQLNEDFMNGGKVLAAAAAAAAAVVAASSSGAKSGGGGSSAPSDDRSDRDNGSLYSGDEFSKDKKNSSLIREGDIDFTDDENGFDIRCEVCDKVYPDLDLLDDHLIGAHHFKQDEFPCKQCALRFCHRPLLIKHEAISHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARCHPCPECGKTFGTSSGLKQHQHIHSSVKPFACEVCSKAYTQFSNLCRHKRMHATCRMQIKCDKCNQSFSTLTSLTKHKKFCDSTGPGPYRNQHVNRHHQHPHQHPLPHQPHLAATATSTCPAPPRESSESSSSAAAAAVAAMSTPPNPFLMFRTAPSFFPGFPPYGFPPFLPQNPLHPTNIPMFFSKNPMDLGCGGPEITSPVSAFDQKLPFGFLKGENSESQAYDKVTEKELVFKAEEKLKKEPLVQAFEGEEDESRSSLDIKGKLEDTRNDSKSEEQDDMKQEPERVSTPDQQQAEDDRKSIDIMSTPPPADTPSGGDGPLDLSICRKRSAGSFFTAPAEDNLMLHRFMPRLHEFEAERGQPLKMRKSHSSAESSTSQKSHKGSSPTPTPTASPGLTPSPSPPTSAGGELSSTSEGGAVPTMAAAAFAADHSALASGPTLPQTHPTFHPLLLEEIYRSGFPFLCQPGGRRGIEALLAGAASAAAPKRPLPPVKFSAGSVVGLKTKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYPCKYCDRAFSISSNLQRHVRNIHNKERPFRCELCDRSFGQQTNLDRHVKKHESEGNNFRDSPSSSGIAEREEYFDDIRKFMNRVYTPNSLAGNEGDTEEYPNSDDQSVNLEKDSGNFNNNSSNISNNNSSSGNNNNSSKAITISS
The following text describes a protein:
Function:
Required for normal localization of actin patches. Involved in tolerance to sodium ions and hydrogen peroxide.
Miscellaneous:
MISCELLANEOUS: Present with 2000 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAFLNIFKQKRGDEASQLSAKGREEISQSIKICKSDDAANEHSCSGDCKTEIEEGEQAFAKLKIEHETPLLNSSKTPKIHFVVPTSQIDWQHDACLEDPKSVQYKISQWCDKNSAKFSNVGTGKTLNCAVSSLPKDIMDIDVMRGTKNNVLILPYFIWLNDLRSDDVEATLDGLVPDLLDENISREKLLETRPNVAVARERAFVFICSHTTRDKRCGITAPYLKKVFDSKLQEHGLYRDNSDYRAEGVKIAFVNHVGGHKFAANVQIYLRNPNTLIWLGRVTPTIVPSIVEHLIVPEEPTLPFPEKVRCIKKYQSW
The following text describes a protein:
Function:
Efflux pump; part of the gene cluster that mediates the biosynthesis of asperfuranone, a probable antitumor agent.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAETDSSHTRGPVDSIQKNDASSDDAEAETKIQYPSGWRVTMILTSVTLAYFLFFLDLAVLSTATPAITSQFDSLVDVGWYGGAYQLGSAAFQPLTGKIYSQFSIKQWTFLVFFIVFELGSVLCAAARNSPMFIVGRVIAGVGSAGMSNGAVTTISAVLPTQKQALFMGLNMGMGQLGLATGPIIGGAFTTNVSWREDAPADDDAGFYINLPLGAVVGGFLLFNTIPEPKPKAPPLQILGTAIRSLDLPGFMLICPAVVMFLLGLQFGGNEHPWDSSVVIGLIVGGGATFGVFLVHQWWRGDEAMVPFALLKHKVIWSAAMTMFFSLSSVLVADFYIAIYFQAIRDDSPLMSGGAISAVGYGLLSTLSPTTSVAKWVGYQILYGVASGCTTAAPYVAIQNLVPAPQIPQAMAIIIFWQNIGAAISLIAANAIFSNSLRDQLAQRASQITVSPGAIVAAGVRSIRDLVSGSALAAVLEAYAEAIDRVMYLGIAVSVMVIVFSPGLGWKDIRKTKDLQALTSDGAQGEATEKETVPVALG
The following text describes a protein:
Function:
Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.
Subcellular Localization:
Nucleus.
Sequence:
MFSKRESAMDWIVFLTNDNEADRKVIEPDHLKRAVQFISPTDYEEDILIERNLSDLCGYPICLKSPKEAKTTLSPIRRNLKNPSYLQHTTGASSTWKTVTSTTSGSQEQEPRFCSQECQARSDYYLTCILKSPRFRTQNQNNGTSDAVCQRDKKIVLLEELDQIDDRPAFQSSTSAKQQGDTLLKSQALDEDQRTKPQQHNFLEPLLNQFQSHNTTRWVDKNLNPIFSSIQIIEHPPQSCLSPSDTLSPVAPHPSNNQDPDQRFFHVAPSSDCSLSKPSMNLVKPDQDLNPIHELSSSLTQALTSQAILSNSNPHRSIAPKPRPEPKDDDHPTPPSTSESELPAPGLLEAEIIYNVGSVEDQFAIDQAMALRDQLGLVST
The following text describes a protein:
Function:
Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.
Subcellular Localization:
Cytoplasm.
Sequence:
MGKLSKDRRDIYYRKAKESGYRARSSFKLIQINEKFGILKLFKPDIYNCNNEKDLINIYNEHYCYNIVDLCAAPGSWSQVLKNICLYNYYQILYMINKYNNNENIKNIQHEEFLNKFSLYINYNEELENKIKNLKIKCSNIKEPNIVAVDLQEIGNMNYVKIIQGDITKMSTIDKILKCMNNKINSDEENVNVFYNMEQQKKENNFSYAHTVVSDGAPDITGMNDIDEFIQSQLILSSLKVCCSVLKVGGNFISKIFRGEHTGLLILHLNKFFQRVYICKPQSSRNKSLESFLVCLNFSLPRSNIISMNNHNAENKINDKYLSEEQMRKFHAQLITYKDKDDQESEEKKENYNSHDNIDYNLCHTTKHNKNISDEIETKEVSSPYEHNNIVENNVTPNSDMLKNINKIINEYDNDKNNLDIFNFYCSDSDEEIKYFNSEDEEVVNNYISSESFMSNKLFSFIATDNYYDSDKSYLLPENYVRHEPQLMPLKPPYMLSLQKKRQEVKK
The following text describes a protein:
Function:
Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.
Subcellular Localization:
Nucleus. Chromosome. Chromosome, centromere. Note=Associates with chromatin. Before prophase it is scattered along chromosome arms. During prophase, most of cohesin complexes dissociate from chromatin probably because of phosphorylation by PLK, except at centromeres, where cohesin complexes remain. At anaphase, the RAD21 subunit of the cohesin complex is cleaved, leading to the dissociation of the complex from chromosomes, allowing chromosome separation.
Domain:
The flexible SMC hinge domain, which separates the large intramolecular coiled coil regions, allows the heterotypic interaction with the corresponding domain of SMC3, forming a V-shaped heterodimer. The two heads of the heterodimer are then connected by different ends of the cleavable RAD21 protein, forming a ring structure (By similarity).
Sequence:
MYIKQVIIQGFRSYRDQTIVDPFSSKHNVIVGRNGSGKSNFFYAIQFVLSDEFSHLRPEQRLALLHEGTGPRVISAFVEIIFDNSDNRLPIDKEEVSLRRVIGAKKDQYFLDKKMVTKNDVMNLLESAGFSRSNPYYIVKQGKINQMATAPDSQRLKLLREVAGTRVYDERKEESISLMKETEGKRDKINELLKYIEERLHTLEEEKEELAQYQKWDKMRRALEYTIYNQELNETRAKLDELSSKRETSGEKSRQLRDAQQDARDKMEEIERQVRELKSKISAMKEEKEQLSSERQEQIKQRTKLELKTKDLQDELAGNSEQRKRLLKERQKLLEKIEEKQKELAETEPKFSSVKQKEESGIARLAQATQERTDLYAKQGRGSQFTSKEERDKWIKKELKSLDQAINDKKRQIAAINKDLEETEVNKEKNLEQYTKLDQDLNEVKTRVEELDKKYYEVKNKKDELQSERNYLWREENAEQQSLAAKREDLEKKQQLLRAATGKAILNGIDSINKVLEHFRRKGINQHVINGYHGIVMNNFDCEPAFYTCVEVTAGNRLFYHIVESDEVSTKILMEFNKMNLPGEVTFLPLNKLDVRDTAYPETNDAIPMISKLRYNLRFDKAFKHVFGKTLICRSMEVSTQLARAFTMDCITLEGDQVSHRGALTGGYYDTRKSRLELQKDVRKVEDELHALEAKLNENLRRNIERINNEIDQLMNQMQQIETQQRKFKASRDSILSEMKMLKEKRQQSEKTFMPKQRSLQSLEASLHAMESTRESLKAELGTDLLSQLSLEDQKRVDALNDEIRQLQQENRQLLNERIKLEGTITRVETYLNENLRKRLDQVEQELNELRETEGGTVLTATTSELEAINKRVKDTLARSEGLDITIDKTEVESKDLVKSMDRWKNMEKDHMDAINHDTKELEKMTNRQGMLLKKKEECMKKIRELGSLPQEAFEKYQTLSLKQLFRKLEQCNTELKKYSHVNKKALDQFVNFSEQKEKLIKRQEELDRGHKSIMELMNVLELRKYEAIQLTFKQVSKNFSEVFQKLVPGGKATLVMKKGDVEGSQSQDEGEGSTQSSVPSVDQFTGVGIRVSFTGKQAEMREMQQLSGGQKSLVALALIFAIQKCDPAPFYLFDEIDQALDAQHRKAVSDMIMELASHAQFITTTFRPELLESADKFYGVKFRNKVSHIDVITAEQAKDFVEDDTTHG
The following text describes a protein:
Function:
Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
Subcellular Localization:
Lysosome.
Sequence:
MTAALWVALIAGLSAAVRDGTATYVYQTKTIDVPIDHFTYTGEATFKLRYLINDTYAPGGADLPASPILFYAGNEGDIELFAQNTGFMWELAPKLKATLLFVEHRFYGHSLPFGNASYDSPKNLGYLTSEQALADFALVLRTLNPPNGTTRARPVIAFGGSYGGMLAAWIRIKYPHLVAGAIAASAPVRQFAGVTDCGIFNQILTSVYQVAYTADCADNIRRSWTTLQNYSTSADGLRLLNEKFKFCTNLTKGTDVTETLFDYLTDVYGNLAMINYPYPSSFLAPVPAYPVREFCGRLAQNYTGVELLDHLQSALSIYYNYDGKAACLNINSSYDGTGISDRGWDFQACTEMVMPICADGVHDMFPPQQWNMQTYADKCFKKYGVHPRPANALLNYGGEFLDASITNIVFSNGLLDPWSGGGVLRSSNENVKIVLIPEGAHHLDLRASNPADPASVTRARAVHVQNIQKWLTEYRKQRKVY
The following text describes a protein:
Function:
Nucleoside transporter involved in adenosine transport and required for nucleotide metabolism which influences growth and pollen germination. Has high affinity for adenosine when expressed in a heterologous system (yeast).
Miscellaneous:
MISCELLANEOUS: Plants over-expressing ENT1 have decreased leaf content of adenosine and show growth deficiencies. Plants silencing ENT1 have increased leaf content of adenosine and decreased rate of pollen germination.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Sequence:
MTPISQRISQKSPKLRETKQIQMTTTDKSAGIVTDSEAGPETSLLLNPHEGSTKKAPSDSYHFAYIIYFTLGVGFLLPWNAFITAVDYFSYLYPSTAVDRIFAVIYMLVALVCLFVIVVFYAHKSLASFRINLGLLLFVIALLVVPVLDLVYVKGQVGLYAGFDVTSAAVALSGLGDALMQGGLIGVAGEMPERYMQAVVAGTAGSGVLVSLLRILTKAVYPQDPDGLRKSANLYFAVGIVVMVICAVFYNVAHKLPVIKFHEERKNEELIREKSEEKGSLTGLAWRTTLWDIVTKVKSHGFGIVLLYMVTLSIFPGYITEDVHSELLTDWYPILLIAAYNVFDLVGKCLTAVFMLEDEKIAVGGSIARLLFYPLFWGCLHGPMFLRTEIPVTILTCLLGLTNGYLTSVLMILAPKSVPLRHSETAGIVTVMFLVVGLASGSVIAWFWVI
The following text describes a protein:
Function:
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
Sequence:
MKMIIGRKIGMTRVFVGNDSVPVTVIKAGPCVVVQKKTVEKDGYNAVQLGFEKAKKVNKPLAGHFKKFGVEPMKILREFRVENPDEYEPGQVIKVDVFEKGEYVDVTGWTKGRGFAGAMKRWGFSGGPKSHGSKFHRELGSVGQHTEPAKIWKGKKMPGRYGNERVTVRNLQVVDIDPENDLLVVKGGVPGARGGLVLIRSAKAPKK
The following text describes a protein:
Function:
VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MRSLIANLLTALVALTSVAHSARENAQEYEALCAAYQAATGTIEPADFNTAQADAEVPTAVKALYAATIPDEHYNNKTFGIFTTDTEFTAVKDTVKTEKNIDKSPVYTRPPESPGKRAALTALERLYNSTKATAGQAAEKQKELQSLKEKAEKFLKAAVFGHETATEAKEENFDTRANACNGGGNAKAASQNLAQALACVCGTASTNNGICVQGEDQANYGTGSGASAGVSAYKAIVAKCQPATEPKKVTAELLTAAVSQVESVLGNKAFTGHTNNGRYVLGNGAAANCNGGDSSATCIDYTTTVGTGTFHKVKWVENMLQATKELKKAYTIRAEQAKMQAQLEAAEAQAWQLRDTLAIATITAAHAAETIKPSKRQRQETIDSKEAECNTKDKDTDCKPPCAWNAEAKDEKKRCTLSEKGKEAAEKVAANQAGTDGKNESKCGEAKTEDECKKVPGKTPEGKKAVCGWIEGKCQDSSILASKQFALSVVSAAFVALLF
The following text describes a protein:
Function:
Possible role could be the docking of the LHC I antenna complex to the core complex.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Sequence:
MASLATLAAVQPTTLKGLAGSSIAGTKLHIKPARQSFKLNNVRSGAIVAKYGDKSVYFDLEDIANTTGQWDVYGSDAPSPYNSLQSKFFETFAAPFTKRGLLLKFLILGGGSLLTYVSANAPQDVLPITRGPQQPPKLGPRGKI
The following text describes a protein:
Function:
Nonessential component of the UAF (upstream activation factor) complex which interacts with the upstream element of the RNA polymerase I promoter and forms a stable preinitiation complex. Together with SPT15/TBP UAF seems to stimulate basal transcription to a fully activated level. UAF30 seems to play a role in silencing transcription by RNA polymerase II.
Miscellaneous:
MISCELLANEOUS: Present with 639 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MAELNDYSTMIDILLSDMDLETVTTKKVRMALKEVYAIDVESQGKAINKLIRKHLDLVKERPRFERSLEDLLKENATLAIELTKEITVSKRSSGEEKNDSETKGTHVEKKKGTVSKSPISTRKVTLSKSLASLLGEHELTRTEVVRRLWAYIKAHNLQNPNNKKEILCDEKLELILGKSTNMFEMHKILASHMTEPKKISDCPPLIQEVRRKEKPIVSDSEQSDTKGI
The following text describes a protein:
Function:
RNA demethylase that regulates the stability of mRNAs through an m(6)A-dependent manner. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing. Plays a role in pathogenicity towards plant host.
Subcellular Localization:
Cytoplasm, P-body.
Sequence:
MTVNLTELDAHEQPSDQMRAIWKSYSRADKEELLLNGAIDDLEKPEKAAEFVVAGTVPAATLTKGFAFLGSGFDAAASDAPIYYHPLLPGLLIFPSIVPLEVQKTLLSKLIHRDLSVPAHQTNMHLHYELPYVERKPTDGEGEPEDCRQSFFSHSPDSPVRFQPKDPDVHKPLSMKQVMDRRLHWVTLGGQYDWTNRVYPEEEPPKFPPDVAGFLETVFPDTIAQAAIVNFYTPGDTMMMHRDVSEETDKGLVSLSLGCDGLFMIAPSDIGKMSEEERPEDVKKQYLLLRLRSGDAIYMIKESRYAWHGVPKVLKGTCPEALEDWPAEDGRFEEWRGWMKNKRINLNVRQMRE
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
LLSLCFRACLDASDREYDYSNNSPRGPQRWASLHRSWTLCSSGSLQSPINLTKETVLRDKTLHKLDSNYNSTAIATVLDWKEDVVLNFPDNAGDLMINATQYKLVQIRVHSPSEHMLEGKTFPAEVHLVHNSTDDSSRIAIVAFYFKLGRPNTFIGQVIDALNSTQNLGELNPTLLKMVGRPYYRYSGSLTSPPCTEGVDWYVVKKNRRMSVDQFQFIHSYVNVSQSHNARPMQPANGREIEAYK
The following text describes a protein:
Function:
Acetyltransferase involved in the biosynthesis of ajmaline-type monoterpenoid indole alkaloids (MIAs) natural products, important plant-derived pharmaceuticals used in the therapy of heart disorders. Catalyzes the conversion of 16-epivellosimine to vinorine, precursor of vomilenine, an intermediate chemical in the biosynthesis of ajmaline. Acts on gardneral, but not on polyneuridine aldehyde or N-methylgardneral.
Sequence:
MAPQMEKVSEELILPSSPTPQSLKCYKISHLDQLLLTCHIPFILFYPNPLDSNLDPAQTSQHLKQSLSKVLTHFYPLAGRINVNSSVDCNDSGVPFVEARVQAQLSQAIQNVVELEKLDQYLPSAAYPGGKIEVNEDVPLAVKISFFECGGTAIGVNLSHKIADVLSLATFLNAWTATCRGETEIVLPNFDLAARHFPPVDNTPSPELVPDENVVMKRFVFDKEKIGALRAQASSASEEKNFSRVQLVVAYIWKHVIDVTRAKYGAKNKFVVVQAVNLRSRMNPPLPHYAMGNIATLLFAAVDAEWDKDFPDLIGPLRTSLEKTEDDHNHELLKGMTCLYELEPQELLSFTSWCRLGFYDLDFGWGKPLSACTTTFPKRNAALLMDTRSGDGVEAWLPMAEDEMAMLPVELLSLVDSDFSK
The following text describes a protein:
Function:
Ligand for the CCHamide-2 receptor CCHa2-R. In one study, shown to be an orexigenic peptide which induces appetite and stimulates food intake, leading to the release of insulin-like peptides which stimulate growth. In another study, shown to be a nutrient-sensitive peptide derived from peripheral tissues which controls growth by directly regulating the production and release of insulin-like peptides.
Subcellular Localization:
Secreted.
Sequence:
MKSTISLLLVVICTVVLAAQQSQAKKGCQAYGHVCYGGHGKRSLSPGSGSGTGVGGGMGEAASGGQEPDYVRPNGLLPMMAPNEQVPLEGDFNDYPARQVLYKIMKSWFNRPRRPASRLGELDYPLANSAELNGVN
The following text describes a protein:
Function:
Adapter protein for SORL1, but not SORT1. Delays SORL1 internalization and affects SORL1 subcellular localization.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MADKEAGGGDAGPRETAPTSAYSSPARSLGDTGITPLSPSHILNDADPVSEQQTFLVVVAIDFGTTSSGYAYSFTKEPECIHVMRRWEGGDPGVSNQKTPTTILLTPERKFHSFGYAARDFYHDLDPNEAKQWLYLEKFKMKLHTTGDLTMDTDLTAANGKKVKALEIFTYALQYFKEQALKELSDQAGSDFENSDVRWVITVPAIWKQPAKQFMREAAYQAGLASPENSEQLIIALEPEAASIYCRKLRLHQMIELSSKAVVNGYSASDTVGAGFAQAKEHVRRNRQSRTFLVENVIGEIWSELEEGDKYVVVDSGGGTVDLTVHQIRLPEGHLKELYKATGGPYGSLGVDYEFEKLLCKIFGEDFIEQFKIKRPAAWVDLMIAFESRKRAAAPDRTNPLNITLPFSFIDYYKKFRGHSVEHALRKSNVDFVKWSSQGMLRMSPDAMNALFKPTIDSIIEHLRDLFQKPEVSTVKFLFLVGGFAEAPLLQQAVQAAFGDKCRIIIPQDVGLTILKGAVLFGLDPAVIKVRRSPLTYGVGVLNRYVEGKHPPEKLLVKDGTRWCTDVFDKFISADQSVALGELVKRSYTPAKPSQLVIIINIYSSENDDVSFITDPGVKKCGTLRLDLTGTSGAAVPARREIQTLMQFGDTEIKATAVDIATSKSVKVGIDFLNY
The following text describes a protein:
Function:
Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein.
Sequence:
MAPPAARLALLSAAALTLAARPAPSPGLGPGPECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGVGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPTCQMPGNLGCYKDHGNPPPLTGTSKTSNKLTIQNCISFCRSQRFKFAGIESGYACFCGNDPDYWKYGEAASTECSSVCFGDHTQPCGGDGRVIVFDTLVGACGGNYSAMTSVVYSPDFPDAYAAGRVCYWTIRVPGAAHIQFNFTLFDIRDSADMVELLDGYTHRVLVRFNGRNRPPSSFNISLDFIILYFFSDRINQAQGFAVLYQAIKEDPPQEKPTDNQMLAEVITEQANFSVSAARSSKVLYVITTSPSHPRQTVPGWTVYGLATLLILTVTAIVAKILLHITFRSHRVPASGDLRDCHQPGTSGEIWSIFYEPSTSISIFKKKLKCQSQPDDRNPLVWRQSARRRPGSQS
The following text describes a protein:
Function:
Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.
Sequence:
MGGKLRIIGGKWRSRKIDFPDLPDLRPTTDRIRETLFNWLAPYIVDANCLDLFAGSGALGFEALSRGAAQVTFVDHSRYVVDKLRKNVEILQATNAQVLCGDFTSVIPFLTTTSYNIVFLDPPFYKNLVERAALHLEESKLLAPNAFIYVETEKNLKPLPLPKTWKIYREKATSSLAYYLFQHLPQKKGVEKG
The following text describes a protein:
Function:
Involved in pre-mRNA polyadenylation. May act to repress the ability of PAB1 to negatively regulate polyadenylation. Negative regulator of poly(A) nuclease (PAN) activity. Promotes mating-type switching in mother cells by positively regulating HO mRNA translation. Localizes MKT1 to polysomes.
Miscellaneous:
MISCELLANEOUS: Present with 2870 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus. Mitochondrion. Note=Localizes to polysomes.
Sequence:
MKGNFRKRDSSTNSRKGGNSDSNYTNGGVPNQNNSSMFYENPEITRNFDDRQDYLLANSIGSDVTVTVTSGVKYTGLLVSCNLESTNGIDVVLRFPRVADSGVSDSVDDLAKTLGETLLIHGEDVAELELKNIDLSLDEKWENSKAQETTPARTNIEKERVNGESNEVTKFRTDVDISGSGREIKERKLEKWTPEEGAEHFDINKGKALEDDSASWDQFAVNEKKFGVKSTFDEHLYTTKINKDDPNYSKRLQEAERIAKEIESQGTSGNIHIAEDRGIIIDDSGLDEEDLYSGVDRRGDELLAALKSNSKPNSNKGNRYVPPTLRQQPHHMDPAIISSSNSNKNENAVSTDTSTPAAAGAPEGKPPQKTSKNKKSLSSKEAQIEELKKFSEKFKVPYDIPKDMLEVLKRSSSTLKSNSSLPPKPISKTPSAKTVSPTTQISAGKSESRRSGSNISQGQSSTGHTTRSSTSLRRRNHGSFFGAKNPHTNDAKRVLFGKSFNMFIKSKEAHDEKKKGDDASENMEPFFIEKPYFTAPTWLNTIEESYKTFFPDEDTAIQEAQTRFQQRQLNSMGNAVPGMNPAMGMNMGGMMGFPMGGPSASPNPMMNGFAAGSMGMYMPFQPQPMFYHPSMPQMMPVMGSNGAEEGGGNISPHVPAGFMAAGPGAPMGAFGYPGGIPFQGMMGSGPSGMPANGSAMHSHGHSRNYHQTSHHGHHNSSTSGHK
The following text describes a protein:
Function:
Potential calcium sensor.
Sequence:
METIAADTFSPSLSSLDFVWLLFVYSNLVVELKNFYSGLLFSIRNKLESLSTLKALEERNISKLETKIRRSNSKFCSTNITPHVEDIEIEAEDIDTVMERLGLTRHAKERETHFSERIERMGREEFSNLFEEQEPSSEELKEAFAMFDENRDGFISPSELQKVLSKLGFDEGTKLEDCKNMIKAFDENGDGKIDFQEFESFMESSFS
The following text describes a protein:
Function:
Is a positive regulator of NF-kappa-B signaling downstream of TLR4 activation. It acts as a scaffold molecule to assemble a molecular complex that includes TRAF6, MAP3K7, CHUK and IKBKB, thereby facilitating NF-kappa-B signaling activation. Regulates TRAF6 and MAP3K7 ubiquitination. Involved in the regulation of cell mobility. Regulates lipolysaccharide (LPS)-induced endothelial cell migration. Is involved in the regulation of skin pigmentation through the control of melanocyte migration in the epidermis.
Subcellular Localization:
Cytoplasm.
Sequence:
MYPLHKSNSEDGCVGKADWKKKNKYFWQNFRKNQKGIMRQTSKGEDVGYVASEITMSDEERIQLMMMVKEKMITIEEALARLKEYEAQHRQSSALDPADWPDGSYPTLDGSSTCNSREQSDDETEESVKFKRLHKLVNSTRRVRKKLIRVEEMKKPSTEGGEEHVFESPPVQDERSALYSGVHKKPFFYDGSPEKPPEDSADSLTPSPSSSSLETWGAGRKLVKTFSKGESRGLIKPPKKMGTFFSYPEEEKAQKVSRSLTEGEMKKGLGSLSHGRTCSFGGFDLTNRSLHVGSNNSDPMGKEGDFVYKEVIKSPSASRISLGKKVKSVKETMRKRMSKKYSSPVTEQDSGLDGTPGSPTSVKPDSEHMDKPKLKAGGSVESLRSSLSGQSSMSGHTVSTTDSSTSNRESVKSEDGDDEEPPYRGPFCGRARVHTDFTPSPYDTDSLKLKKGDIIDIISKPPMGTWMGLLNNKVGTFKFIYVDVLNEEEEKPKRPTRRRRKGRPSQPKSVEDLLDRINLKEHMPTFLFNGYEDLDTFKLLEEEDLDELNIRDPEHRAVLLTAVELLQEYDSNSDQSGSQEKLLADSQGLSGRSPRDSGCYESSENLENGKTQKPSALSTKSSTESNLKSFNRSQPGNYPTLPLTKSGEVRKQGEESRLGRGLAPDTAKCCDVPCVTGLSKNRRSLPVSICRSCETLEGPEPVESWPRSHSLDDLQGDADVGKDVPTEKPETCPENVPEVPQKASACTSKALPRGRDPTAEDVMFLTQSKRFSDPPKTMAKKLEGSAVASNLGIAPPQCIPRNFEAQPPVKPGLTRTSLEGLRKGHDHHSLGTKEGVDGEQSTPETRTQSRHPSQPPPVPAKKSRERLANGLHLVPSPEAPILPLKKASPASPVSPSDCPSPREPRSSSGTEPGSPVCTRPPPWLAELPESTSLQEHGVKLGPVLSRKVSCIRGVDLEMLTENKLQAEGIDLTEEPYSDKHGRCGIPEALVQRYAEDLDQPERDVAANMDQIRVKLLRKQHRMAIPSGGLTEICRKPLSPGCVTSVSDWLISIGLPMYTSTLSDAGFSALSQVPSLSHTCLQEAGITEERHIRKLVTAARLFKLPPSPEAM