lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.
Sequence:
MIRILHTADWHLGQTFFGYDRAEEHKAFLDWLAEEIRQNEIDALVIAGDVFDVSNPSAASQRIYYEFIYRVTAENPKLQIVIVAGNHDSAARLEAPLPLLQAMRTEVRGVVRKLEGGEIDYDHLTIELKNREGEVEVLCMAVPFLRQGDYPVVETEGNPYMEGVRELYARLLQRLWARRKTNQAILAVGHLQATGSEIAEKDYSERTVIGGLECVSPDTFSEKIAYTALGHIHKAQRVSGRENVRYAGSPIPMSFAEKHYHHGVVMVILDEGCAVDIRRIECPQSIPLISVPGGEAASPEKIIEILRDLPEVDGEAPYLEVKVLLEEPEPMLRQEIEEALAGKKYRLARIVSAYRQEERVEKEVDGWKKGLQEMSPLQIAQSAFEKVYQAEMPADLTDLFQEAYISATRKEEEEGE
The following text describes a protein:
Function:
Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors.
Miscellaneous:
MISCELLANEOUS: Plants over-expressing OFP15 show small rosette size, late flowering, reduced fertilization and blunt-end siliques.
Subcellular Localization:
Nucleus.
Sequence:
MKLPFLNKNHSTSSYSSNSSSSSWPWPSCNQNPKTLSFRATITFTNPIHDQDDDELDLLDPPEITDSVENVIKGLRSSERLIFESKGETNSILEEATSKREEEDEEEGFMLFSLESDDPYSDFKRSMEEMVEAHALHHDWKSLEKLLLQFLKVNAKTSHRYIFAAFVDLLMNLALDTKKAIINNDISKDDGVSASRAAAAGEASTSCCNSMTLGESPSSPLSFYTSCSSSSSSDETSSMSVRFLPLSSLLEMDEKTKEILV
The following text describes a protein:
Function:
A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
Miscellaneous:
MISCELLANEOUS: In the RecBCD complex, RecB has a slow 3'-5' helicase, an exonuclease activity and loads RecA onto ssDNA, RecD has a fast 5'-3' helicase activity, while RecC stimulates the ATPase and processivity of the RecB helicase and contributes to recognition of the Chi site.
Domain:
The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA; The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.
Sequence:
MSAPSNNMILPTTSQALPLDPLTLPFGGSRLIEASAGTGKTYTISGLYLRLLLGDGLSEPLSCEQILVVTFTNAATEELRDRIRRRIQVAFKCFLGLEINDPFVQALYDKTPESERAIALRRFDLALKSLDEAAIFTIHGFCQRILADLAFESSLLFESDFTLDDSEFLHHAVRDFWREACYPLPEYLAQIIASEFGDPDGLVKQLRALLGASEAKPLKPVQPFARLAESLSQSVQRFKLAWPRGRDALLALLHSLPLNGQRFGKASDNYPKLAEMFDQLDNFIAFGHGLPPLKVLEALSLSELKLNKGGVLPSVSEAPLLDHMEQLATLINAIKPAFLFSAKQGISERFAKQKQLKNVLTPDDLLTTLAAAMLANPDTLPKAVASRFPVALIDEFQDTDPLQFAIFSWIYQTRLGVKAQNSTAVEPKARTDSKLSLLMIGDPKQAIYAFRGADIYTYIEARRQTQAHYFLDTNYRSSRNLVAGVNHLFAQHPNPFISQSIPFDRVKTPASAAAKQLVESTANSAALRLKLLREGETGLNKASARQTLAEDTAAEITRLLTEAANGQCHTPKGPLIAKDIAILVRDRNEAAVMKTALSKRQIGAVFLSRDSVFDTVEAREMALILRALASPKDERALRSALATALLGYSAEQIHAFNQDEEQRQMLLEQFFALHQIWQKRGIMPALLSLANATHMVARLLQTPSVTATADQDSEEPDEASNGERRLTDFRHLAELLQQKATEIDGISALLNWYEQQLIDNTGTDEQQLRLESEQNLVQIVTIHKSKGLEYPVCFIPFVSLARDNRRRPTPMLYHRTDADGAQELVWDIEGTDEGWEQAKQETLAEDLRLLYVALTRPVYLCYLYIANHSRMLKAGIKSQLHETAIGYLLGVTDAGCDFARLHSAAQALLNGVESNAQAISVECVADNIADNKLHTGETQSHTLNARNVTRQYRTPWRVGSYSGLVKNAPHAKASPGADDEVSAVFGAEPANSLSESSWQDSADVPQLPLLNRFSFERGANAGSFMHLVLELIDFTQAKIDLPRELPKAMLQYGIAPEWQTVLQDWYMEILQAPLALMAQDNQLINPELCLAALVPQHTLVEMEFYLPLNRLKDAELNQLLGQFGYDTALHFDELQGMLKGFIDLTFEYQGKFYIADYKSNHLGDTIQAYHYGALKQAISDHRYDLQYILYSLALHRYLAMRLPNYDYDIHIGGCYYLFLRGMSVQYPGFGVYYDKPPKALILALDALFNRSQDESHMSQQNTGAMA
The following text describes a protein:
Function:
May catalyze the formation of 25-hydroxycholesterol from cholesterol.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MTLAHIFQTIWDFGTKDSVLQPIWDYVRLNHSETLRSPLFPVVLTVSSYFVLVLPYLSCDILGRKWPAIYRYKIQPDKLPTTAMLLHCSGVTLYNHILLVIPAAVAQWMWRPPIPLPEQAPTLLELVGGVTGNLLLFDLQYFIWHFLHHKIRWLYVTFHAIHHNYSAPFALATQCLGGWELVTVGFWTTLNPVLLRCHLLTTWMFMVVHVYVSVEDHCGYDFPWSTSRLIPFGVYGGPSKHDVHHQKPNTNFAPHFSHWDKMFGTHADFRFSKPRE
The following text describes a protein:
Function:
Rab-3 effector.
Subcellular Localization:
Synapse.
Sequence:
MTKSTKLRHCKQKKKKPEKTPKGNPPILITEKSIEDAATTTSTTDALLGSPEGSRSKSRKLKLCCCTAQAATLSPLDPTSYGGIASTSAHNGMVGGLSRDSRAASRTSKRGSSKSLNRPQIDADEPSTSGTNPDRRPSTHFVLDLPVVSTRLRKLSEAFFNAQHGDKIDLMNDWEIGGTQNKWVCPSDRHLHLRAQLKSGWSVRTATARSPTNSKAQTGSITAAEQEHIQKVLAKAEESKSKEQQRIGKMVDRLEKMRRRATGNGVTHCLLCHTEFGLLASKSYAAMCVDCRKYVCQRNCGVETTDVNQTTGKVETVFLCKICSEAREVLWKKSGAWFYKEMPEFQRPDDRLPYYVPVTTNGTLPNASSAATPLSGTPGGAGPQPMTMPSTSSCQMTTPKWASPGVCNSPGLQMNGGPTSPLPNGTRRNTGHGGIEFPSSSRPSICSVLQAIEPLDRSKSPRPRIQPRWVNEKVMSSMSVDDEEKAASSSDGESFVQSGVPRRALNNKTPVGSTSATTSPAPPPTSTTPTSRREANMERFSRHTHAHANRLYSTDDDDDSSPESRPSTRSTSPRHSLATPSSYAHDTCHDTSLPDADTRSIDSGVVQSDHSNPQQSGLTCSSSSLTPLQQQASHDHHSGGGTPRRISNPDRTTSRVAQSASGTSLVTPPPPISSRTSPDNCNSSPLNVMEHKSSSASTASSGGNRRVGSAEPVLNNHHAMHNNQNHNDINKKLISQTSRAESPLAASSSFLSSPDDDTKQKNRRRDGVGRVNSLQLRTSLDDVAPPVAPISKMNGHIVSSEPTSSTTSNQNHTSVPIPTVPVVPEEEEEKAITASTESASEPGSLGSITLTLTYHSADKKLKMHLIRAKNLKAMDSNGFSDPYVKFHLLPGNTKATKLTSKTIEKTLNPEWNEEMSYYGITEDDKEKKILRVTVLDRDRIGSDFLGETRIALKKLNDNEMKKFNLYLESALPVPQQTKEEENEDRGKINVGLQYNIQQGSLFININRCVELVGMDSTGFSDPYCKVSLTPITSKAHRAKTSTKKRTLNPEWNEQLQFVVPFKDLPKKTLQIGVYDHDLGKHDDYIGGILLSTSAKDERGRQWIKCIENPGTLVEAWHRLELDS
The following text describes a protein:
Function:
Involved in the transposition of the insertion sequence IS5.
Sequence:
MKTFTDFALKEKYKHIQLVGDNLSELESLIGWKRFRLILEPMYVNKTASGGRPEADVIVMFKMLVLQQWHGLSDPELEKHCIDRLSFRNFLGFPDYIPDSTTVWLFRKGIIDNEKEEEIWDELQSQLDSHGLKIKKGMIQDATFIHSDPEHAKADKPRGNEAKTRRSRDGTWTKKGSKLYFGYKLHSIIDRDYELIRRFKTTTALVHDSQVDLSEENEVVYRDTGYFGAEAKGFAATMKRAVRGHPLGIRDIIRNKRISLKRVPGERVYAVTKNVFSSGTVLVTTVERVNMKMLFTAFCYNLHQLRTLKRKGVF
The following text describes a protein:
Function:
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MGKLIALGISLILVVGVVIGTVVGVNKGRHPKDDLSSKDIASGSTSTTMKSVSAICASAYYEDSCIRTLTPVAKNESATPHDYLKASFEAIVEEVQAALEKFGVIGKDANSSIDKMAVGDCKELMQYAISELQSAISMVNDPKRHPASDXVAELKNWLSAVVSYEETCTEGFEHPKLKSSMENGLLNATQLTGNALAIVTELSAILRALNIRLDTNINSRRRLLDAQGYPTWFTLKDRKLLALQGNGQLTPNAVVAKDGSGQYKTIAEAIAACPKNSVSRYVIYVKAGTYDEYIIVTKGQNNIFMYGDGPTSTIVTGKKSYATGTSTFRTASFSVIGDGFIAKSMGFENTAGPQGHQAVALRVQGWMPWNGTFALDTLLYAEYNNRGPGANTAQRVKWKGFKVITDRNEALRFTAGPFLLGNEWLKDTGAPFILGLKY
The following text describes a protein:
Function:
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression.
Subcellular Localization:
Nucleus.
Sequence:
MKEAIEKCVDSQLWHACAGSMVQIPPLNSNIFYFPQGHAEHTSTDVDFTALPRISAMILCRVNAVKFLADPETDEIYAKIMLIPVENKNHDFENDTVLGSSAVETTEKPSSFAKTLTQSDANNGGGFSVPRYCAETIFPRLDFTAEPPVQTVIAKDVHGAIWKFRHIYRGTPRRHLLTTGWSSFVNQKKLVAGDSVVFLRAENGDLCVGIRRVKRGGIGGMELNSSGGRFRDKGQVSPESVVKAAYLAASGQRFEIVYYPRASSPEFCVRASSVNAAMNVQWCSGMRFKMAFETEDSSRISWFMGSISSVQVADPIRWPHSPWRLLQVTWDEPDLLQNVKHVSPWLVELVSNMPVIHLSHFSPPRKKLCLPQDFALDSQFPLPSFLGNPLRSSSPFCCLSDNITAGIQGARHAQFGVPLLDLQLSKKIQLGLLPPVSQPLDADSRIPNGISKVQKESNENISCLLTMGSSSQMLDKADNLKTPRFLLFGQPILTEQQMSSGRSTNVPPQVQTKRDSSGEAQMETERISLGWKGLSESLSNATLLWNKGYHAAELGMSTGHCKVFLDSEDVGHALDISVLRSYEEVYKKLADIFGLERLDMMTRVLYIDATGASRQIGDAPFSDFVKTAKRLTILKNPDNSAARKWLTDLPTAEGCLDSSNQAGSLSIFA
The following text describes a protein:
Function:
Dynein-attachment factor required for cilia motility.
Subcellular Localization:
Cell projection, cilium, flagellum. Cytoplasm.
Sequence:
VSFAQMEKDLISALESDAHNQLENEAKLRAISQRVSYDEFRDIVRGVHLKPVPSGSLSVNKPQKGRIWNNIALSKKSYETEACEARKGTAATPANNYSLNQLPISAQFLNSWQQSDTKSRLLILYKIGPAGLNNIFTIDMPTALLGEIFEALLCFNPVTDVVAVIKLMEALTKIKRFNLIVHFLNASERATCQQLIHKLLASLVQREQDFAEEGIT
The following text describes a protein:
Function:
Has transcriptional repressor activity, probably as part of a complex with YY1, SIN3A and HDAC1. Required for B cell lymphopoiesis.
Subcellular Localization:
Nucleus.
Sequence:
MSRPEKFRLTSGIGVQPPESLVRPQREQDPNESEDDVELCITLDDQDCKGEEHRRKRKRGKEDEEEQKEAVCDFDETLDQALEDRAKQHNLTAVNVRNIIHEVITNEHVVAMMKAAITETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNLSPIKKVSEVKAPQFVDIPLEEDDSSDEEYRPEEGEEDETAEESLLESDVESTASSPRGHKRPKVCHLPEAVGMEEEDESVEGPQEPPDTPGFARYVSADVVPMGPPPPPKSKPTQDSTFMEKLHAVDAELAFSPMCMDSYQSLDESLIAFRTRSKRPLKDVPIGQLEAKLKAPDITPDMYEQNTADDDEWKKWLRSLMEDDMGNEDEGDDEDDPEYNILEDLDEPDTEDLRNDRAVRITKKEVSELMEELFETFQDEMGFSHVEEEGPDEDSNQEALPNFNTPQAIRFEEPLANLLNEQHRTVKAQLESLRLRKSLMKPQCQGADESTPAPEEPKAPPPAKAAPVMFLDETQRRRLQQQMQQHVQLLTQMHLLTCQNHQLSQQADLSRMFLVELSSFAEKSTMLRQMANPEFQSAFQPWNLKEALQLLHDFHQQLPEEGALPKPLKKNASEAASLPTHMAWIMATRPLFMYPELLPICALKAKGPRDRVYFTKAEDNLLALGLKHFEGTDYYKPLISKYLVTGKSAQQLTVRIKNLTMKKTPENIIKFYKRTKLLPVMLKFCDDAQSPGAKAPVEREKHRLPFWLKANLSSIEEEFGKYKKGAQTYPLTPPPGLQLNMKPLPQRFLHRSWRQKRSSILKPLLIRPTSNIGTNCPFPKTVAKMPSPDPFPIGLYARVSSLVQPQPAVQGLVGIHPADVPAGGKSQEVRATLPFAARPSRLHPPPVAPVPIAPAKVLQPAMLNQRARRLLGGMTRRRTAVRNPAIKAAPLVHSAPVIFAVPSATLKLVSLGSPCGVIQPISSRGGVPVTTLLLNPPPVPVSQTLVPSALSQTPRAEPERLVGGDTTEGQVQSEGGTTFKEEDEWDCVSITIKVKEEGGLVPGGHTDCGGEGTSAASHIKKERVSPFRPGEKPPQKENCPFYLTEVPLEPGSEYDPPECEQRGGAQTCESGSGLCEQQGGQGPRELGDEGQAVGHASGTQEPSGSSAGQRHRDHTLGKEGKTKENHGNRSSPSPAGLGAEPDEKEETEDVAMEEEDGGNETQNPDAAESPKNTSSSTDGDVDISSPAGTPLDSSSPSGRPESANDKDGPEEEEEEDFDDLTQDEDEEEISSASEESVLSVPELQETMEKLTWLASERRLSQEGDSEENSQEENSEQEEEEEEEGDEGIEPSSQKEEEMTDEVAEGGTESAQSHLCPTLPMPVETRAVPAGERRRGSSRGPGSHRVRSRRGRARTSKDASKLLLLYDENILAKDPLREQKDMAFAQCYLTRVREALQYAPGRYEEFLQLIYQFESSRRERTAVDLYERLRGLLRDWPQLLRDFAAFLLPEEALECGLFEEQQAFDKSRKFLRQLEICFMENPAQHQKIIKLLQSCAECPLQEITKLKAQMWQLLRGHNHLQDEFSMFFDQLRPPASRLGEFEVMTWTEDKEYKFDGYEEVTLPDVEEEEESGKVAAPRTKRKKDQDKEGEWQECSCLCHEGATEPRLKRSKRRICTQCSTKVCDSRAQRARDPPEVMAGGLPRSLRQGPTMKEVGKCNHGNMLPSWSSVTNCSCLSAPGEGALPPRDTQDRLSAELPVGQRGSSDTSGSNSNMAGAQRARGSTHSRAPSVPGSTSLGKPRPGTRDSPRTPAPPHPRSSRRPLCMKDPDQPPNKLLPSSTAPPRELNPPVPSVSEQSLASIILCSTPSAGPGTDPLDPNSKESPDPDEQTSTVCAKNITVSSSGEKVILWTREADRVILTMCQERGAQPDTFADISQSLGNKSADEVSRRFQDLVSLFQTACVTSSDEEEEAGSTAELLSDQEVED
The following text describes a protein:
Function:
Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. Involved in mitochondrial DNA mutagenesis.
Subcellular Localization:
Nucleus.
Sequence:
MGSILDANSSAVRKSIENHQFDNEEGEEYEASNFGGFGDYMRRKKIKLQNLDAEIRSSSPDRPPIFRGVVAHVNGYTQPSLQDLHRLIVSHGGGFLQYLDGKTAATHIIASSLTLKKREEFKRYRIVKPAWVVESIKAGRLLPWDAFRVVDEGHAQKVLNFDNGRLLSQANVQQSGYRDQSDFSWYTSRLKGLGMLAEEAPSVTEPPEVPEQIAQASAADEATKTATESDYGDFPSFASSDPAGNIPGVPKSEQSDSPKHLDAEDTAAADVGRRMPTQSPVIVTDQHPPLAGESVPIKTEMTPEEYNAQLLADPRMRNSSVVNPEFLQQFYRESRLHHLSTWKAELKAQLQAAAKEKSHSQAGRKKPAPGARRYVLHVDFDSFFAAVSMLKHPELKGQPVAIAHGTGSGSEIASCNYPARARGIRNGMWMKGALQACPELKVLPYDFPAYEEASKKFYSAVLAVDGVVQSVSIDEALVDITLQCLEAGGSDGRGISEGSIYREQAKADEIAQNLRESVKAATGCDVSVGIGGNILQAKVALRKAKPAGQFQLKPDSVLDLIGDLTVQDLPGVGYSLGAKLEELGVKLVKDVRGVSREKLINHLGPKTGLKIWEYARGIDRTEVGNEVLRKSVSAEVNWGIRFVNQTQAEDFVKSLCEELHRRLSDNLVKGKQLTLKVMRRAADAPLEPVKHLGHGKCDVFNRSVVLGIATNAPEVLAKEAISMLRSFGITPGDLRGLGVQMTKLEPLKLGATNKPEGSQQQLKFKASPARKSHEQVRDPDDLDSPRKADAAAVSHGPTLNDDSYKPLNISGTQFIMPSQADPKVIAELPSDIRSKLMSQGKGRQASRSTSPCPAARRTQTSTATALPPQSQLDPDTLAALPEDVRAEILGYYGRTSSTPEPQPAVSTVPSSRPASSGSLGIKKSSTPTKKRRGRPSTKGTGNMTLTQSNFIIARSTLTPVNTEEQASSRQPSPSPDPEISADFLAALPEDIRREVLEEQKRARKLQRSGLQLPAPRKVAPSTSTPAAQEKRLRLPPLPERPTFTSKKLTALTDLRDEVGAWHATFADEGPFNEDVETLARYLKSVVVDEKDIDKAVSVVTWLMWLVEDANATRGGECQSGSSHGTITWEAAIRSLQKGVSDGVEERGLPPVEFS
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MAGQTDSVTVPLENGIKSFSQPLALDKAPFSPTAAAHCHQATSSLSNGHDMTSIPEMSDEDRTKLLPEIPPNTFPFGELLSRTVQTTYTDLLDLAETLPSASNDERKKQLLNFCFAKRKLFTKLLVLLRASSKSKDIMTCQRVHAFIDHQDGAFSRTADDLFAIHSQMRVAKIANYDIQTAVDVLTTGTYQRLPKSLKAQLVSEEPLTADEVSRTKERLNDLIRMRLTCEEVVPAALRHNMKIENGYVLFKVPGEFSVTLTMSPGNSEQPWTLVDLQILAKSTSTGYGGSLPSLQPTQLQAFKDASQRHLADDKSSYWLIVRLYEFIHKFCLTYQLHILSSQASYLCQNRWMDHLQVEKQELVLKLNMWHNPSASNAVSYREYYQLRISAEYIPTVYPDRSFEPMSDSDGLQKVVLESLSQMIVNSGKNNGLKISLIGILGSTVRDIDIPDMIKLNTESLDIEELLLSITDYQSRIIICAMRDELLTNASDSSAGSLVHSAFTSEHVQMSMGIEAETGNSTSPTIKSMLPAASLLVMYRPESWVRLSVNPRTGIVIASLADASGLGSLVGANSSTCSPISENAPAGSTLSKESGNGLKRITTSIDRNLKIVEQQINANVRNTKQAILYLRRATTITQIETMALYLGLEVADFAHIGTDSPLKHLQTDKVRLTHLRFPGKDDNVLVIAAGTPNDIHHDNALHSQVSDTVIYSEDAEFYVWIMSLKPSEHRTKKPEFQIIPLSPADVPGVLDSTDSLIDVDTSFLTAKLRLSKTSQHQSFSQAWPRIDLPVLSKIQTASSNLFAFAKLTEQLDLNGLTYQILVKNIPGYIPKGQTHVGDIHIARLNPKVVLSVRELFSLYGHAAFKSTHSSNSSTMDPGSNMHIPNSNIYVYLEPAKSLSFSAKSQSPTAKIDAISTEHHTHRIVAKMRLPDRLLSLEAHSLKISEYIEYDGTSQTITFQYHSVNEYIECFITEFLRVISMIYLTLQLKRYTKALENMNVKMDFFNLLMVNVQLFPNTVMQIKWLPQHDSQTNESGFSVWHGEYAASFQHNDGSPDELMVIADLFTAILNKTKEIFPLIQLLHRVAPLVSLLEHIRQRRVAFGQTGVVLKILSLTHFRIVFPYFSQLCGIEFVYERPGSFMMFDASMLDYAAELGLGSLAKVGLGIFCDDSIVDNSIDTEHTLRPLPEYIDMPAVSVPGMDQMRPPRIGLLYTLGTRVAQELADSATATTDPPRSSRQVADTPTHSKHGSIVVLPHGILCTFSMIDTVMVGIEGYIDVMCASDLIFSYLKTQPVTHSIHEEQHCRILFATESSKAALTCHSNGRWGFVIAATERTHDNKAAVANIPDSKAWLDRLNHDVNAIPIPKRNSLQWLKTVVHIAMLPDIPLRELMSVTRVSNSLNNTKPLALEWILQSPPDAPPHIPAPGEMSFIFDRDLERMRLLYRFTDTTTQESVLIPIKYNFGSGVISIWHNEAGDAIYPDITPYHPLDPKMEGLMKTLTNTNLPSLPILERTFVQASIKHIPPTMGGPGKLFAVLKHLTSRNILELKSGVNVQ
The following text describes a protein:
Function:
Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation.
Subcellular Localization:
Nucleus.
Sequence:
MQQQQARLQQQLQAPGASADAVQQQTQAQLLQQRQMALLQRQQQQQMAAALHNQRANFQAVPFPGVSGAMSQSALASQPLQMPVNMSQVAVKTPGSIAAVSTAPGTVALSPGNGAAAGNSILDELEREADEMANGVNDQPLSMPESELQAATTPTGTLNAAIGNNFVNLTPTSASPTIVGAAGTGSFSAAPLSMPPDISSGVASPATSSSAGLAQLTPAMISAASATAGTNTMYNGMNLTGPQIQQIQQIQQMQQLRRMQQLQQLQQQQLNGKVSAAQLQAGATVPTSGVSTTPTSAAGGSGVTPGMIQMNEVSIAQKREELKRRLIQLKHARTCTTGECAIDYCSRTKALLSHVSRCANAQCSTLGCKSTRQLLSHFRKCRNLQCDVCSAIRPPMNENEQQLVLRRQQERLCMLRHATVPAGGSASAKQAPAGSAQQNNGASVKTEGVSVGGSDQGQKSGAGASVTASKESSLLDEMKKKPLKLQTEKEKKLRRKEQAKIAKARAQAKAAAAAALTGPVAGALATPGAAQPVMHNGLVVRGTQAELRGDHHVSHQDISFLDSMTEGQLDEHIRSLRFNFCGHISIAELKSRLMPLLTKLMDSEYGWTFNNPVDPVQWNIPDYFDIIKCPMDLGTIKKRLESEHYNSVEAFAGDVRLVFENCIAYNSSTNKFNIAAKQLLASFNKSLASLKNQLEKQLFKRCEQRREEMCQLCGGDSFKFAPCMLFCSGPCAGRIRRHTHYYSDPRGEHHWCSSCYKQMKEGPIDMSLLPQLSSAATEVAPPPGAGAALFDGVLKKSSLVKRKNSEVAEEPWVECDSCKLWYHQICALFNERNHAISGEQEPFVCPICVKKQRATGVKPSLDNGLKAKRLPITRMAKLIETRVMEAIEKAGKDEAVRMGSMGNSDSIGFSNGVKESASDTQFGITIREVLSIDKQVQVKPRMAKLLAAKYGKTKKAETGATATQSKSLKRPRSTMSAADKKAAASASASSVLSLQLTYRSRCICVFQELDGVDVLIFTLYVQEYGADSLSPNAGRVYVSYLDSVNYFQPKKLRTLMHQQVMLGFLEDCKNRGFHTCHIWSCPPLKGDDYIFFCKPENQKIPKSARLRQWYQKLLQQAKHDGLVANMSNLYAEYYMKKKAAHELPYFEGDYWPRLAEDLIKQLEEKDNGNRVKTGTPGQVDAAGNMASASGASTPANGAKTPITRSPSPSDASNENDVATDSATDVKATASKKGAMTPGSKNKSKRSKKGAPTEPSVTRSSASKARSKKGDKSSRSASSSKNVINNDPLMQKLKGILEPQKDDFFVVDLYPKCHKCGVPIVHEGYWELKTIPPPASVNNLLEATKKTRSSSSSSRNSPPRHYHYFYCGSCYDSNKTQLLHRVEVSSNCAKRARDLSERILPLNEKAAAAELAELDLQEIKFEAVLNFVDTEQEVEEETQVKDDDKSMAETKQSEELKTEKSEDKTRISDVDANVSTEASDTAATEASNKPADENAESRAAPATEKAADASSNKEKQTEENHKATEQTKETIAVTAAVSKKHKHIGAELDDLIMPCEIFDTREAFLLYCQNNHCQFDQIRRAKHSSMMVLYHLFNQGTTGFTFSCSNCKTTLLSGNRWNCSICPVFNLCDTCHTKTKHEHQLHLFKVVSIPRPGNEVSNETVSTKVKGVVSTAGGAAGRAIKREAGSSDLKRAKHAKGAGKKAGGSRKRKLHQPSSLIATPTSTTPAVKPEVAAAPATVPEGAEANAAPDAAAASASADSAANGANGNTSDGDAAKKRRIHNIDPQLLLQLEHASSCTAPNCTFFNCNRMQAMLKHGAICEQRLAGPCVLCKRIIGLLSAHARQCTKDYASCKVPRCADIRRHFLAQVQARQQQLQRARQLQAQQQAMANAATAAAASAATTPATGEETKDAAAS
The following text describes a protein:
Function:
Catalyzes formation of 5-hydroxymethyldeoxyuridylate (5HMdUMP) as a step in the pathway that replaces dTMP by thymidine hypermodifications in the viral genome. As a final result of the pathway of hypermodification, hydroxymethyluracil substitutes for a subset of thymidines in the viral DNA. These modifications probably prevent degradation of viral DNA by the host restriction-modification antiviral defense system.
Sequence:
MYTFSGSKPTQLYMDILSTVIKEGDVLAPRGKRIKEIRPVMIEFKNPIRRTTFLKGRNINPFFQVAESLWILAGRSDVGFLLDYNKNMGQFSDDGVFFNAPYGERLRFWNRSDANNFIYNPLDQLRDVYEKIKADPDTRQAVAVIYNPLFDNINNDTKDRPCNLLLSFKLRNGKLDLSVYNRSNDLHWGTFGANLCQFSTILEAMATWLGVEVGSYYQITDSLHVYLDDYGAKITEDIQKVYGVNLETDEAPVVEDFEELLDPNPRMSYTMNELNQFLNEYFGIVDSLMRDDETYMHDGDCAQMLLNQIRHEPDEYIKVTLLLMVAKQALNRGMKDTVATAMNWIPLCEIKVSALRFLYKSYPEYINQYDLDEKLMKYIRREE
The following text describes a protein:
Function:
Phosphatase with broad substrate specificity. Does not have phosphoglycerate mutase activity.
Sequence:
MTAVCLVRHGETDWNLQQKCQGKTDIPLNATGERQARETGEYVKDFSWDIIVTSPLKRAKRTAEIINEYLHLPIVEMDDFKERDYGDAEGMPLEERTKRYPDNIYPNMETLEELTDRLMGGLAKVNQAYPNKKVLIVAHGAAIHALLTEISGGDPELQSTRLVNACLSNIEFAEEKWRIKDYNINSHLSGFIK
The following text describes a protein:
Function:
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
Sequence:
MTHVFEVYPKVNIFLKILHKEGAYHKLISRMCLVKDKLKDIISVKSALSFSLKGDFDCPLEENSLFKALQILKNFLKSKNFSHSVIKSLDTLAIEVEKNIPTQAGLGGGSTDAGGLLYHLNQIFDWRLSLEELYSMGSLVGADTNFFISQYKSTNATSYGEVIENFEEEPLENRLEIYAPNHVFCSTKAVYQAYKPETCFSQAKEWLKKPSLECLKTYDRNGLNDLLKPALLTNQALKDIESELGKEWFFSGSGSAFFRLKPMQKGGE
The following text describes a protein:
Function:
Part of the ABC transporter FtsEX involved in cellular division.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSKLANTESVAPSRFGVWIDHHLHSIAFSLGRAMRKPWATLLTIVVMALALALPLGLSIALDNVKLLAGSVQQSREINLFLKVDVAADAAERLAGELRARADIAQVAVRTPAQGLADLRENAKLDEAIDALGDNPLPTLLIVTPADATDDAQLAAALQALPQTDQVQHDALWRKRLDGWLHFGERLVQVLSALLGIGAVLVVGNTVRLDIQSRREEIGVLQLLGASDGFIRRPFLYLGAWYGLGAGAVALALIAASGFALRTPLATLADSYGSSFTLHGLDLLHSAMVLVGTLVLGWLGAWLVTGHFLRQTRPTET
The following text describes a protein:
Function:
Found in membrane microdomains that may be equivalent to eukaryotic membrane rafts. FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity (By similarity).
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein. Membrane raft; Single-pass membrane protein. Note=Present in detergent-resistant membrane (DRM) fractions, approximately 6 foci per cell.
Sequence:
MDDIVNSVPSWMFTAIIAVCILFIIGIIFARLYRRASAEQAFVRTGLGGQKVVMSGGAIVMPIFHEIIPINMNTLKLEVSRSTIDSLITKDRMRVDVVVAFFVRVKPSVEGIATAAQTLGQRTLSPEDLRMLVEDKFVDALRATAAQMTMHELQDTRENFVQGVQNTVAEDLSKNGLELESVSLTNFNQTSKEHFNPNNAFDAEGLTKLTQETERRRRERNEVEQDVEVAVREKNRDALSRKLEIEQQEAFMTLEQEQQVKTRTAEQNARIAAFEAERRREAEQTRILAERQIQETEIDREQAVRSRKVEAEREVRIKEIEQQQVTEIANQTKSIAIAAKSEQQSQAEARANLALAEAVSAQQNVETTRQTAEADRAKQVALIAAAQDAETKAVELTVRAKAEKEAAEMQAAAIVELAEATRKKGLAEAEAQRALNDAINVLSDEQTSLKFKLALLQALPAVIEKSVEPMKSIDGIKIIQVDGLNRGGAAGDANTGNVGGGNLAEQALSAALSYRTQAPLIDSLLNEIGVSGGSLAALTSPLTSTTPVEEKAE
The following text describes a protein:
Function:
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MILACDVGLKRIGIAALLNGVILPLEAILRHNRNQASRDLSDLLREKNIQVLVVGKPHESYADTNARIEHFIKLVDFKGEIVFINEDRSSIEAYENLEHLGKKNKRLAIKDGRLDSLSACRILERYCQKVLKNH
The following text describes a protein:
Function:
A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, dehydroepiandrosterone (DHEA) and androstenedione. Has 16-alpha hydroxylase activity. Catalyzes 16-alpha hydroxylation of 17-alpha hydroxy pregnenolone, followed by the cleavage of the C17-C20 bond to form 16-alpha-hydroxy DHEA. Also 16-alpha hydroxylates androgens, relevant for estriol synthesis. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
Subcellular Localization:
Endoplasmic reticulum membrane. Microsome membrane.
Sequence:
MWELVCLLLLILAYLFWPKPKTSDAKFPRSLPFLPLVGSLPFLPRHGHMHVNFFKLQEKYGPIYSLRLGTIPTVIIGQYQLAREVLIKKGKEFSGRPQMVTLGLLSNQGKGIAFADSDDAWQLHRKLALSSFALFRDGDQRLETIICQEASSLCDLLLTHNEESVDLSQPIFMSVTNIICAICFSTSYENRDPILTTIQTFTEGILNCLDNENLVDIFPWLTIFPNKTLEKIKRHVKVRDEVLIDMLEKCKEKFNNDSISNLTDILIQAKMNADNNNTTDHQGSFSDSHILSTVGDFFGAGIETTTSVLCWIVAFLLHNPEVKKKIQKEIDQNIGFSRTPTFNDRNHLLMLEATIREVLRIRPVAPMLIPHKANIDSSIGEFTIPKDTHVVINLWALHHNEKEWDQPDRFMPERFLDATGSHLITPSLSYLPFGAGPRACIGEVLARQVLFLYVACLLQRFDLDVPDGAPMPCLKGDPKVVFLIDPFKVKVTVRQAWKDAQAEVGTWRP
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular Localization:
Mitochondrion inner membrane. Mitochondrion membrane.
Sequence:
XGLLLARGSKIKKLVYPPGFMGLAASLYYPQQAIVFAQPGNVKNSPGTK
The following text describes a protein:
Function:
Involved in pre-rRNA processing.
Subcellular Localization:
Nucleus.
Sequence:
MSRLIVKNLPPYLDEAGLKKHFSTVKDPKSAGFAPSDITDVKVVRARDGKTRRFGFVGFRSDETAEAAVKYFDTSFINSTKISVAVAMTFTDPNVPLSSRERKRQAAQRAREDAEDDREAKKARYLEKPMTIDDINGLGNASDPRLADYLDAMQVRSNAKTWANNDAGAVANEPQVIQSTASDDEYDEFTGKGDDEIDEDEDEEEESENKKDDDNEEAEEDEEDPVIEDGLAADPGVSDMDWLRQRQTRIKEGEPEEDRENRHTESKSEGKKGKGNAPKAATPVDEEPSEDPTIVSIRKTGRLFLRNLLYTAKEEDFRQLFSQYGELEEVHLPINTKTGQCKGFAHVQFEDPENAIAAYEAQDGKIFQGRLLHILPGKPKKDYNRLDEHDLKNLPLKKQQELKRKAEAAKQQFSWNSLYMNQDAVMESVAKSMGIKKSELIDPDSSDAAVKQALAEATVIGDVKSYFEKMGVDLASFDNKDRDDRVILVKNFPFGTTQPEIAEMFSEYGDLYKVMMPPAGTIAIVIFKHIPDARAAFAKLAFRRFKTSILYLEKGPKNLLPNEKMESDEVEHVKQDKIVTIEDKLSASDVMDTGSNDERPATASTSVFVKNLNFKTTSRVLTDAFKALDGFLVAQVKMKPDSKNKGKFLSMGFGFVEFSSKEAAEIAQKAMDGHVLDGHKLQLKISNRGQDEETTETKKAIDSKILIKNLPFEATKKDVQKLFGAFGSLKTVRVPKKFNSESRGFAFAEYVSAKEAEHAMSALQGTHLLGRRLVLQYAQADASNAEEEIERMQATVSKQAAQRSFADMKLAGEGKRRVDLEGEDEEEF
The following text describes a protein:
Function:
Controls heterocyst pattern formation. Required for the differentiation of intercalary heterocysts but not for terminal heterocysts.
Subcellular Localization:
Cell septum. Note=Localizes at sites of cell division.
Sequence:
MKTLPITRYRFFQKIQPLSLLKKITGKTITGCLQVFSTSGTWSIYVEEGKLIYACYSERMFEPLYRHLGNLSPQIATLPKEINEQLRAIFETGIENQAIPNPDYLAICWLVNQKYISSSQAAVLIEQLALEVVESFLMLEEGSYEFIPESFLDDLPKFCYLNVRLLVEQCQQHGRVPEAFRREASSQEISSSTEHNQIPVNNRRSTKFTSPPHTQPKPEPRLPQINTNKSTEYSKRYASQPNTVNHGYSQTSATSTDKKIYTIFCIDENPIVLNNIKNFLDDQIFAVIGVTDSLKALMEILCTKPDIILINVDMPDLDGYELCSLLRKHSYFKNTPVIMVTEKAGLVDRARAKIVRASGHLTKPFNQGDLLKVIFKHIT