lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Sequence:
MFSGIIQEVARVDLIHHLRDSMEIGVFARKLIDVVPGSSFSVDGICLTLVKRQYELLFFDVTEETMAWTTIKDYTVGTMVNLERSVRLGDEIGGHFVSGHVCGIGTIIAIEKSYMFFKAPANLVPYILEKGFIAIDGISLTIARVKGDIFSVSLIPETRARTSLGYKQVGAHVNMEPDMMTKMQVDTIMRFHAEKEISK
The following text describes a protein:
Function:
Nonribosomal peptide synthesis (NRPS) is a key mechanism responsible for the biosynthesis of bioactive metabolites which are potentially contributing to organismal virulence.
Domain:
NRP synthetases are composed of discrete domains (adenylation (A), thiolation (T) or peptidyl carrier protein (PCP) and condensation (C) domains) which when grouped together are referred to as a single module. Each module is responsible for the recognition (via the A domain) and incorporation of a single amino acid into the growing peptide product. Thus, an NRP synthetase is generally composed of one or more modules and can terminate in a thioesterase domain (TE) that releases the newly synthesized peptide from the enzyme. Occasionally, epimerase (E) domains (responsible for l- to d- amino acid conversion) are present within the NRP synthetase. NRPS6 has the following architecture: A-T-C.
Sequence:
MTAIDVPWLSTPRRDNSHGTRSNSSCQPSCTQRIAVPISPDAVKYPLAVFCFAWAVTLGAYLDSQELVIGFAFHGWDGDTSIPSAGTCRIRIRPEQEILPALDEVVADGDKGLRSWVAQGAGSETDIAIQRKEVGDSLHPAVHGDEKLSPEIIITPSGNQGPYHVQGRFDPHIVAPALAHMMLHQFAFAVQGIVRGQSSIASSQVKDLQAISPDGMAQLMRWNRQSAAEEDGACVQDLIQRTCQQQPHAMAVCAWDGSWSYQELDCQASHLASQLCDHGIEPEKFVGLLFEKSKWTTVAILAVLKAGGAFVLLDPTQPAAYLSAICTMTRTALLLCSSHNQRLAAELRQTTIQVPRDPYHGAMPTSDFRRQSSPAVQPHHTLYACFTSGSTGRPKGFIIDHVAFNSGLQTYAHATGLGCDSRVFQFASYSFAPSITDQLASLIVGASICVPAEEELQNDVEGSISQLQATWLKLTPSVARTLDPGRLPCVKTLILVGEEAQVSDVAAWQDHGITVLGLYGQSENAKGTMVSRKSSEDADPGNIGSPFCAVGWVVDPDDYHRLMPIGATGELLLESPCLCRGYIDNEDETKLAFVSKPSWLTQVRGQGTAQPLLRTGDIVRYNCVDGTFCLVGRKGNRVKLRGQRLELAQVEHHLRSCLSSTHPVLADVVQPANENGRDPMLVAFVPWADSQSAADATDGFFAPPTKDFQTQARAVLGRLRHLLPSFMVPSTLLAVRTIPRTGTGKIHRRRLQEAASMLSRKQLMAYISPFIPYRAPETELERKLQRACGRLLNIEADQISMQDNFFDLGGNSLTARQLVAVARAEGLQVSVAQIFQQPTLAGLAQTHRHPVRRAEVPRSSHDPDPFGRVRDDVRREGLPHIARGNIEDALPVLYTQMTTARDHCVDFFPLRVIGGQLDPEQLRLAWTRVIQAFPILRTVFPRFRGRFIQLVVRDIGDSNFYRVVEAPSGQTAEEWARALCTEAIQFRCPVDRPVAQLTLIQAAGSSALVLRLCHAQYDGSCLEHLVRSLMMAYHGRPLVVESDFQAYTRTCLRLRIPEVLDFWRRFLAGSSPTQLASSMTGDREAARKINRSFFRREVNSLAAPAGFTLATVVKAAWSWVLRNETRSEDVVFGQLVSCRGSVPLPHADTIIGPCMNIIPVRVGRDLLGAVQAQHAQTMEFDMIGMDEIVRHCTSWPAGTEPDSIIIHENFHVDWEVHDGGVTIQKIAAVFNQQPSSLTFLITIPTETGLIAVLMAPANMSSTHADRVLDLFCNTLTRLAWSPAAVLRRSE
The following text describes a protein:
Function:
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Sequence:
MPPKSVYYAVANGRTPGIYSNWDDAKQQVTGYSSAKYKKFSSYEEAQNFCQQGKQAIYGTSSNSSNCNSYDTHNDHAIRNSVKTFIARKSNPPVLQNKLTGNRSYEYDGYRRAEKFTARKSNPPVFRDDIPGYKAYDHSANGREKRFTARKSGMPESRIGYGNNAIEKSSVHTARKSEPPITTGHLSFIHDPSLRVQLYETENKSSNAYNPHSTTNSTSNSDRTTVYVDGSCLGNGKHGARAGVGIYFPNMPEASLAEPLPGDTHTNNRAELHAFIRAMQVTKGSVDVYSDSRYVKECLENWHRKWIKNGWKSASNKPVENQDLIKTALELKRDRDISIHYVPGHSNVPGNEAADRLARMGAGQL
The following text describes a protein:
Function:
Receptor for Wnt proteins. Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes. The beta-catenin canonical signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Coreceptor along with RYK of Wnt proteins, such as WNT1 (By similarity).
Subcellular Localization:
Membrane; Multi-pass membrane protein. Golgi apparatus. Cell membrane; Multi-pass membrane protein. Note=Colocalizes with GOPC at the Golgi apparatus.
Domain:
Lys-Thr-X-X-X-Trp motif interacts with the PDZ domain of Dvl (Disheveled) family members and is involved in the activation of the Wnt/beta-catenin signaling pathway; The FZ domain is involved in binding with Wnt ligands.
Sequence:
MEWGYLLEVTSLLAALAVLQRSSGAAAASAKELACQEITVPLCKGIGYNYTYMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYNRTDLTTAAPSPPRRLPPPQPGEQPPSGSGHSRPPGARPPHRGGSSRGSGDTAAAPPSRGGKARPPGGGAAPCEPGCQCRAPMVSVSSERHPLYNRVKTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFLIDMERFKYPERPIIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAATAGAGAAGAGASSPGARGEYEELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDNLRGFVLAPLVIYLFIGTMFLLAGFVSLFRIRSVIKQQGGPTKTHKLEKLMIRLGLFTVLYTVPAAVVVACLFYEQHNRPRWEATHNCPCLRDLQPDQARRPDYAVFMLKYFMCLVVGITSGVWVWSGKTLESWRALCTRCCWASKGAAVGAGAGGSGPGGGGPGPGGGGGHGGGGGSLYSDVSTGLTWRSGTASSVSYPKQMPLSQV
The following text describes a protein:
Function:
Small subunit of the DNA topoisomerase that untwists superhelical DNA. Controls topological states of double-stranded DNA by transient breakage and subsequent rejoining of DNA strands.
Miscellaneous:
MISCELLANEOUS: There is a 50-nucleotide untranslated region in the coding sequence of gene 60. The ribosome apparently skips this region while reading the mRNA.
Sequence:
MKFVKIDSSSVDMKKYKLQNNVRRSIKSSSMNYANVAIMTDADHDGLGSIYPSLLGFFSNWPELFEQGRIRFVKTPVIIAQVGKKQEWFYTVAEYESAKDALPKHSIRYIKGLGSLEKSEYREMIQNPVYDVVKLPENWKELFEMLMGDNADLRKEWMSQ
The following text describes a protein:
Function:
Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded, thereby facilitating ribonucleotide turnover. It also participates in Ty1 retrovirus-like transposition via an RNA lariat intermediate in cDNA synthesis.
Miscellaneous:
MISCELLANEOUS: Present with 1130 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MTKLRIAVQGCCHGQLNQIYKEVSRIHAKTPIDLLIILGDFQSIRDGQDFKSIAIPPKYQRLGDFISYYNNEIEAPVPTIFIGGNHESMRHLMLLPHGGYVAKNIFYMGYSNVIWFKGIRIGSLSGIWKEWDFNKQRPDWNDLENNNWKANIRNLYHVRISDIAPLFMIKHRIDIMLSHDWPNGVVYHGDTKHLLKLKPFFEQDIKEGKLGSPVTWQLLRDLRPQWWLSAHLHVRFMASIKHNKRSHEPPNKSTSKTKKNNNEIDLDLSSDEDERSGIMNCQEENEYDSKYGETRFLALDKCLPRRRWLEILEIEPDTSHASWKDENHRMFWDPEFINNLVICQKNKNLLSNKPFNSVNWIELSQSNREEGRDIDWENYAIPAYTLDIQKDEVRQTKAFISKFMT
The following text describes a protein:
Function:
Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Regulates negatively the transition to flowering time and confers flowering time delay.
Subcellular Localization:
Nucleus.
Sequence:
MLDLNLDVDSTESTQNERDSITVKGVSLNQMDESVTSNSSVVNAEASSCIDGEDELCSTRTVKFQFEILKGGGEEEEEDDDERSAVMMTKEFFPVAKGMNFMDSSAQSSRSTVDISFQRGKQGGDFIGSGSGGGDASRVMQPPSQPVKKSRRGPRSKSSQYRGVTFYRRTGRWESHIWDCGKQVYLGGFDTAHAAARAYDRAAVKFRGLEADINFVIGDYEEDLKQMANLSKEEVVQVLRRQSSGFSRNNSRYQGVALQKIGGWGAQMEQLHGNMGCDKAAVQWKGREAASLIEPHASRMIPEAANVKLDLNLGISLSLGDGPKQKDRALRLHHVPNNSVCGRNTMMENHMAAAACDTPFNFLKRGSDHLNNRHALPSAFFSPMERTPEKGLMLRSHQSFPARTWQGHDQSSGGTAVAATAPPLFSNAASSGFSLSATRPPSSTAIHHPSQPFVNLNQPGLYVIHPSDYISQHQHNLMNRPQPPP
The following text describes a protein:
Function:
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
Miscellaneous:
MISCELLANEOUS: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
Domain:
Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.
Sequence:
MSKDEELLQNYCSILFTYKTIGISNLHLYYFRETEIKSLKQLINAEFAILQTCNRVEIYLYSDTNTLKEVNKIIQYLNNIHNEPIGNQARVLCGKDAAKHLFLVASGADSLSIGEYEILSQIRSTIDMFKKLGFSGKYLQIFFERAIKVGRKVREETSISKGKVGIYSLAIDEAKKRFNDFYDRRILVIGAGEMAQKITSMLHNEGAKDVTIMNRTIEKAKQLALKFGYNYEKLDLDKLGNFDVAFISIYHENLRLENKWNTLIVDITVPPLFTGNNVITLEELERISNLNFKAREEELAKINKLVEDGINELLYDYKKEIYTEFMSKIMKRIETIRENEILRAYKELEKLGINDQQAKEILDLMTRSIIKKSFQPLFDNIRSLIFNGENSINYINFLIDIFKDGNISGFETEKIKEKQVSERSSI
The following text describes a protein:
Function:
Secreted effector that interacts with and inhibits the pathogenesis-related P69B subtilisin-like serine protease of host tomato. Inhibition of host proteases by a pathogen extracellular protease inhibitor forms a specific type of defense-counterdefense mechanism between plants and microbial pathogens.
Subcellular Localization:
Secreted. Note=Localizes to host apoplast where it targets defense proteases for inhibition.
Sequence:
MKSAFTLSLALVAVTATISAAADDNCSFGCLDVYKPVCGSNGETYSNSCYLRLASCKSNNGITEAGDGECASTPASSATPSPVTSSTGSTSGTVGCPDMCLDVYDPVSDENGKEYSNQCYMEMAKCKGTGYDDNKRSGNPGISTLDAERKLAFAPGYQGPPCGDMLCPDNYAPVCGSDGETYPNECDLGITSCNHPEQNITMVGEGTLPVTGAATATATATAEVVTRW
The following text describes a protein:
Function:
Non-catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSKLSEKEAFLFDRSIDQFEKGQYSKSLKTIQSVLKKKPKHPDSVALLGLNLCKLHDSRSALLKCGYASSIDPKSQFCWHALAIVYRETKDYNNSLKCYQNALAISPNNESLWYDAAYLQAQLGLYQPLFDNWNRLLQLDSSNLEYRLCFTLSAFLSGNYKESLEQIQYLISSCNLSPLVVSRLISFLPRICEHIENGSQTVLEILLMNQNSFLNNFNFEHIKADFAFRQKNYEESIYLYARLLIKFPNRLDYSEKYLNSLWNFYKSGGLALDLLLKRTDSLIKTFSEILQTGISVLIFLLSKNLDYDFCLNHLISYSMHHFIPSFISLLKIPLKTNDAFSKKLITMLSNFREGDSAKNIPTHKLWCTYCLCLAHYKLGDYEESNYWLNLAIDHTPTYPELFLAKAKIFLCMGEIEEALCSFKRSVELDKSDRALASKYAKYLIRMDRNEEAYIVLSKFSRFRFGGVCNYLAETECVWFLVEDGESLLRQKLYGLALKRFHSIYQIYKKWSFLKFDYFTQCAEDGEFQEYVELVEWSDNLWSSTDYLRATLGALTIYLLLFESKFNMYGNKAEEISHMSEVEQIAYAREDNKKIMKLQKIEEDKIKSYIPSESEEPLVIDEDYFGHKLLITDDPLTEAMRFLQPICWHKIKGWGFLKILSSKLYKLKGIIFCYYALTNNIEGLHQKANSLETSVL
The following text describes a protein:
Function:
Plays a role in germline stem cell maintenance, perhaps acting in concert with mRNA-binding factor fbf-2 (Probable). May regulate fbf-2 by modulating RNA-binding and perhaps by competition with the intramolecular interaction between the fbf-2 RNA-binding domain and C-terminal tail.
Domain:
Contains two Lys-Xaa-Xaa_Leu (KxxL) motifs, which are essential for the association with fbf-2.
Sequence:
MCSTFILPPRRNNCNKSSSTIAYSKSQHEAPKQLLQLRSEIKPLIPLNQPSNFWESSQDSGVLSSLSSSPQQRSGLRSQKLHLTYIEKNKRVRAMIPQQQHYHAFDRPTHYNSRKTSGPPPLMRTPSSGFSSASSSENMFSGLTLSDNENKIHEIMDPSVDVDLDMFLLPDCRYKQPVQPSTSTSRNNVSQISGSSRLNGSTRHVAPIVPKVAMPSELSYANVKRSSGYVDYMPTTYNSNVTSNSSAASVPMSPGTWVRCHYCWESYVKLCQRVANLEPLISCDGPWNWHTLYDMQGRVTCPRLWFAQLDRAGSEMVEQMGHARNVPV
The following text describes a protein:
Function:
Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteromeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteromeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton. Cell junction, adherens junction. Note=There are at least two distinct SYNM subpopulations, one in which SYMN interacts with DES within the Z-lines, and another in which it interacts with both DTNA and DES at the costamere.
Sequence:
MLSWRLQTGSEKAELQELNARLYDYVCRVRELERENLLLEEELRSRLSREDRWAEDQALYAEEARSLRQQLDELNWSTALAEGERDALRRELLELQREGVEAGTARSRLDAELGAQRRELEEALGARAALEALLGRLETERRDLDAAHERQVRDLRARAASLTMHFRARATSPAAPPPRLRDVHDSYALLVAESWRESVQLYEDEVRELEQALRRGQESRLQAEDEARLCAQEADALRNQALELEQLRARLEDELLRMREEYGMQAEERQRVIDSLEDEKEALTLAMADRLRDYQELLQVKTGLSLEVATYRALLEGESNPEILIWTENIENVPQEPRNTSYRYTNSVLQRKNEKNLFPRRKTPWAAVNHSSASYSNWPGHLDSQTTTAVGSAARRGLLTSRHSSSATTSGQQKPLEKTISSRANLRPVTPTHGFLRNTDAQMKTLPHRSKVEGTGDTHARRATESVITRESYRGHQGHVAAGAVSSTPSNERTVILGKKLEAQATKEQERDRSGVIRIKPEEKMFDSKEKASEERNLRWEELTKLDRDARKRESRHLRDEAREKEALKERSVKEREVPISLEVSRGSRAEVSTIHLQSPGRKDVSHSGGREAETKETRFRLDTQDTASSLQSDSTTETIAESIVTTILKQFTQSPGAEEEATSFPDTKVTYVDRKEFPGDGKTKTEIVVESKLTDVVDVSDEAGLDYLLSKDVKEVGLKGKSTETMIGEMINLGLKGREGRAKVVNVEIVEEPMSYIGGGKIDFSTPFQVEEVDDVSPSPKGFVEEEDGEGETHMAFSMRPHQTKQPQGTIPHVEEVTEAGDSEGEQSYFVSTPDEYPGGHDREDDGSVYGQIHIEEESTIRYSWQDEIAQGTWRRKMRGDVGGEKPVKVLEVPALSLGGAIGSAHLKEEASGELRAEPTVIEKEIKIPHEFHTSIKGVFSSEPRHQLVEVIGQLEETLPERMKEELSALTRQSQGESGSVSVDVKKVQSAAGGSVTLMAEVNLSQTVDADQLDLEQLSRDEAGEIERAVESVVRESLAKRSSPVPRSPDREDGEEVPAGGILFKRWATRELYSPSGERDDAGQVSPSSDQRVTQGPVSATVEVTSPTGFVQSHVLEDVSQSVRHVKLGPTEMWRTEQVTFGGPTAQVVEVSGDFSEAVSSEGASRSVRHITLGPHQSQVSTEVIFRGSVPTWQETGDTEKPGPVVLSVGADISGSGRMPGSERSHTEKEIRFQGPVSGTAQVGGNFATEESVGSQTFVRSLQLGPKEGFREEIQFIAPIPDKVGWGEEDSEHTKVSLERATSIQRIDIVPQRYLASKQMAPQTLEFRDSEDMVMVEGSAGTIQATHNFTSDREILQNKENTFQRVISGSPPDSVGDTGAEVTANVSRSFRHIQIGPTEEEPSEYFVTGRPVSKTFVLDGSVASPGLVGGADGGSTPCRIALGPKETSFTFQMDLSDTRAIRSWTRDTGSEVEAHGVSHRGGWRIAHSRDERVASTGSGASPGDAHQAPGEKGTEQAGFDKTVQLQRMVDQRSVASDEKKVALLYLDNEEEEEEEGEGWF
The following text describes a protein:
Function:
Thought to play a role in cellular copper homeostasis, mitochondrial redox signaling or insertion of copper into the active site of COX (By similarity). Participates in copper and redox homeostasis.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MLPCRRLVLSCKNQAASFLRRCGPSKRIQSVNYCKSTRQGHEIPDVKPLFPTGGGTQAPSRSRARYAVPAILLGFAGFVGFLHYNDERRAVPRGQASSNSGCGCGSNTTVKGPIIGGPFTLVSTENKIVTENDFCGKWVLLYFGYSFSPDVGPEQLKMMSKAVDKLESKHNEKILPVFVTLDPQRDTPSHLHAYLKEFDSRILGLTGTASAMRQMAQEYRVYFKKVQEDGEDYLVDTSHNMYLINPKMEIVRCFGVEYNPDELSQELLKEVASVSQ
The following text describes a protein:
Function:
Probably catalyzes the synthesis of phosphatidylglycerophosphate by transferring a phosphatidyl group from CDP-diacylglycerol to glycerol 3-phosphate.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSRSTRYSVAVSAQPETGQIAGRARIANLANILTLLRLVMVPVFLLALFYGGGHHSAARVVAWAIFATACITDRFDGLLARNYGMATEFGAFVDPIADKTLIGSALIGLSMLGDLPWWVTVLILTRELGVTVLRLAVIRRGVIPASWGGKLKTFVQAVAIGLFVLPLSGPLHVAAVVVMAAAILLTVITGVDYVARALRDIGGIRQTAS
The following text describes a protein:
Function:
Involved in cell adhesion. May be involved in the attachment of the actin-based microfilaments to the plasma membrane.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction. Note=Cytoplasmic face of adhesion plaques.
Sequence:
MPVFHTKTIESILDPVAQQVSRLVILHEEAEDGNAMPDLSRPVQVVSAAVANLVKVGRDTINSSDDKILRQDMPSALHRVEGASQLLEEASDMLRSDPYSGPARKKLIEGSRGILQGTSSLLLCFDESEVRKIIQECKRVLDYLAVAEVINTMEQLVQFLKDLSPCLSKVHREVGAREKELTHQVHSEILVRCLEQVKTLAPILICSMKVYIHIVEQQGRGAEEAAENRNYLAARMSDELQEIIRVLQLTTYDEDTSELDNLTVLKKLSNAISNKMEQANEWLSNPYALRGGVGEKALRQVIDNATEISERCLPQDSYPIRKLADEVTAMANTLCELRQEGKGQSPQAESLVRGIRDRMGELKSLVHQAVLGVDKAGVQQTAHTIQGRLEQAVKWLQHPEINDGGLGERAINLIVEEGRKVAEGCPGHQKAEIQQLCDEVERLKRQAAGSGPAAKQAAKQLTQKLYELKAAIQNALVNRIVQDFMDVSTPLKQFTEAVLQPEGTPGREQNFNQKSNNLQAFSDRASKTSRMVAAGGACGNKKIAEILLSSAAQVDSLTPQLISAGRIRMNYPGSKAADEHLQNLKQQYADTVLRMRTLCDQATDPADFIKTSEEHMQVYAKLCEDAIHARQPQKMVDNTSNIARLINRVLLVAKQEADNSEDPVFTERLNAAANRLERSLPAMVGDAKLVATNIADPAAAAAWKNSFQRLLGDVREVRDAIAPPQPPPLPTSLPPPIPELSALHLSNQNAERAPPRPPLPREGLAPVRPPPPETDDEDEGVFRTMPHANQPILIAARGLHQEVRQWSSKDNEIIAAAKRMAILMARLSELVLSDSRGSKRELIATAKKIAEASEDVTRLAKELARQCTDRRIRTNLLQVCERIPTIGTQLKILSTVKATMLGAQGSDEDREATEMLVGNAQNLMQSVKETVRAAEGASIKIRSDQTSNRLQWVRRQPWYQY
The following text describes a protein:
Function:
Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Responsible for energy coupling to the transport system.
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MPLLEVENLSIDLGDFHLRDVSLSVEENDYLTIIGPTGAGKSVLLEAIAGFYPLLKGRVILEGKDITREPPERRGMSIVYQDYVLFPHMTVFENIAFGLRKKGLVRAEIEREVRHIAEELHIDHLLHRKPGTLSGGEQQRTALARALVVRPRVLLMDEPFSALDSKTREKLRSLVRNVIDEYGTTVLHVTHDFEDVFALAKHVAVMRDGRIVQFGTPEEVFSRPADEFIADFVRTNLLRGEVVGKEGELTAVRVGNVILYTADDAEGKVTLSIRPEDIILAREPGECSAQNVVPVLIESLEKRGHLVWLSLSSEGVPLSAVVTPNAAELLGIKPGEKFYAMFKASALRVIK
The following text describes a protein:
Function:
Member of a network of 50S ribosomal subunit biogenesis factors which assembles along the 30S-50S interface, preventing incorrect 23S rRNA structures from forming. Promotes peptidyl transferase center (PTC) maturation.
Subcellular Localization:
Cytoplasm. Note=Associates with late stage pre-50S ribosomal subunits.
Sequence:
MAEFHDDDSQFEEKSKSQIKRELHALQDLGERLTTLQPQLLERLPLTDPLRKALLEAPKHKAHIARKRHIQYIGKLMRDQDVDAIVALIDQVDSSTRQYNERFHALERWRDQLIAGGDAALDAFVGEFPECDRQHLRGLVRHAQHEAAHNKPPAAARKVFKYIRELDETKRGLR
The following text describes a protein:
Function:
May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MGLMNRSKNDEYVKLLGAWPSPFVLRTRIALNLKNVAYEYLEEEDTLSSESVLNYNPVHKQIPILIHGNKPIRESLNIVMYVDETWLSGPPILPSDPFDRAVARFWDVYIDEHCFTSINGVAVAKGEENINAAIAKLEQCMALLEETFQECSKGRGFFGGENIGFIDIGFGSMLGPLTVLEKFTGVKFIHPENTPGLFHWADRFYAHEAVKPVMPDIEKLVQFARLKFNTSIFK
The following text describes a protein:
Function:
Not required for the biosynthesis of any of the c-type cytochromes. Possible subunit of a heme lyase.
Subcellular Localization:
Periplasm.
Sequence:
MNKGLLTLLLLFTCFAHAQVVDTWQFANPQQQQQALNIASQLRCPQCQNQNLLESNAPVAVSMRHQVYSMVAEGKNEVEIIGWMTERYGDFVRYNPPLTGQTLVLWALPVVLLLLMALILWRVRAKR
The following text describes a protein:
Function:
Involved in the degradation of glucose via the semi-phosphorylative Entner-Doudoroff pathway. Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) yielding 2-keto-3-deoxy-6-phosphogluconate (KDPG).
Sequence:
MAEGRCSQGKEPAEAMISLVALGEPLIQLNAVTPGPLRYVAYFEKHVAGSEANFCIAATMAGARCSLIARVGDDEFGRNIVEYLRGRGVDVSHVKVDPGAPTGIYFVQRHFPVPGRSRLIYYRKGSAGSRVGPDDVDSSLISSADAVHSTGITLALSDSANRAVHKAFGEAKRRTFDTNIRPALWPDLAAARRAILDVLNYGVDVLVTDPDDTQILLGVRDPEEAYRKYRELGVQTLVYKLGAEGAYVFWNGGSYFRDALKVAVEDPTGAGDAVAGYFVALYLSGVDPRRALDLAVAASALVVGVRGDNEALPSPREAEELLKAL
The following text describes a protein:
Function:
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Required for modulation of the activity of the hermaphrodite-specific neurons (HSNs) by the G-protein coupled neuropeptide receptor egl-6 which in turn controls egg-laying behavior.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Perikaryon. Cell projection. Note=Detected in perikarya and neurites of HSNs.
Sequence:
MTLSVPDCAEMNRIRMSNHRKMSLGSAPLIANGRPSPPPRRTSLAESIRTLAFTARRNSSPLYRKSTKKLKKSRLVGKNGICNVYNTNVPKKDRQYLRDIFTTMIDVKWRWMLMLFASAFVLSWSIFGTTYYLIALVHGDLSLPTPVNHTACVMNLDSVYSSFLFAVETHHTIGYGHRYITTECYLAGAIVCLQAICALLLQSFMVGIVFAKMARPKKRAETIIFSDKAVICLRDGQLCFLCRVGDMRNTHLVEAHVRLQFITDRETNEGEIEPLHQFEMKVGPSIADDDRLFLVWPTTLCHVIDSRSPLYNYNQQTLMSAQFEIIVLLEGIVESTGMTAQAKTSYLPSEVLWGHRFRKLVTYQRSNGSYQIDYDLFHSTYPVRTPAMSPAEFYSSKPNLKDYYCHDSHEHKLEDNRSSDSTPLPSPSPYSYPSTPLNHFQSSSNSPVFSNNHSKFNTEAVTCEAGMLCPPTIVVQCPSTCASPNHMRRTRNQMDKSRTSSSCDLTRPSTALSDLEEECSDSGSPTKCQSPPVVPIHIEIVSET
The following text describes a protein:
Function:
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
Subcellular Localization:
Cytoplasm.
Sequence:
MPGASMESSRKHAGRALEDLDLSTEELGRFEKAMKDPKFVEMLSEYAREMEDPKLREENEKYLRQLEREGQGGAVYGKDTELVAPNAGFCVKTKNKITGAKAFINICHSDKIGAATSTPRTDSTGADWSIPYSLSTARKEKDKAGKECDVHDFVIGSATYERCRTDRRFKTFVIETALDSVEAQRKCKLDRSFTLPKLKFKGLSDSPPVLAVKASGKRDEDSTPKDSPVSPLQPSNRANRTASPFAFDKAAKSTALTTAMAAGAQPSSNEETLLKSAQYKPAETAMDKEDGRETPVSGECAPSGKITEVVSTSKASGDTEAQPNFDIVQQGLMDLSSFWLDERTGPVQASRPESLLLRVDLPLLESAAAVDLDVSEQRVVLRAVGKYLLDAALPYPVEETKGRAKFDKLRRRLEVVLPVVRPQAPPRKPFEEPRPAATVDDDSLGSCAEPSADSAAVADAFAEAVEPPEPESTGSLEATTQSIGDGSKLFLNGTAGEFEEEPRKGAADRTESNGSGTVLGNQQVVDDGSPLPCAAEVPQTGPACAAEEEVTRNVDATEQGEMSAIEDAAISKVFSMDSLMGARSVEDVPGLANGKGVAAETVETPSVVVPELVQLATEAPKVEERDPSQKSTRVAPLRYQPKLTCSLVYDID
The following text describes a protein:
Function:
Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
Sequence:
MIKIGAHMPISKGFDRVPQDTVNIGGNSFQIFPHNARSWSAKLPSDEAATKFKREMKKHGIDWENAFCHSGYLINLASPKDDIWQKSVELLKKEVEICRKLGIRYLNIHPGSHLGTGEEEGIDRIVRGLNEVLNNTEGVVILLENVSQKGGNIGYKLEQLKKIRDLVDQRDRVAITYDTCHGFDSGYDITKKEGVEALLNEIESLFGLERLKMIHLNDSKYPLGAAKDRHERIGSGFIGEEGFAVFFSFKEIQEVPWILETPGGNEEHAEDIKKVFEIIEKFGIEVD
The following text describes a protein:
Function:
Common component of the spliceosome and rRNA processing machinery; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSHSVTSSEMKSSVSVTFPMAEEKVEHKASKLIVRAREAKTLARGTKEVAKYIRRGRKGICIIAADTHPIYVFAHLPVLCEQNGIPYFFIKSKKALAEAAGTTGTASVVLLQEPSKDASDGEDRKTYKKIYQKAEDALKALKKHVEIH
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MPDASMEDCDGFQTQFTHIMETLLQTAVRETTKLYQSTLQSLKAELVHLRVENVNKKTAHSSCQDTRRFPQTGIQRTGSVSKYRDVGVQCENALLAERACSPRQFIGQRLHVGDITSDKLTDLCASEDGNRQLALLLIKQEPQESECDEYAPGYFLLKQEGAEPILVRKEPNKDTMERVVIPPAVQTITRHQSNPRGKSPPPVTPLSSNLSVTSCGHKPNQSTQPIQGTSLSTKENREGLSSQNKKQDASVPAQTSTTSVPNSSIPARTACAKLSVPMIQLSGAPSIPQAKQSTSLVHRRPSPNPHASNQTVVPQKEESDMCHPLQNTILSAVPSSQVVVAEPTSNKQRALFTHTEKSASSITSINQATQTFAQCSAKLTQPPFIQPQAIKNQAQEMTPVVHTAMPSGLVPATSSKPTQVHDRRGTNLVPPRPHAFASPQVIPAHSGAHSNPSFSFPAVQPVVPTPAKPTSYLPMLVSFSSSHLPVNTIPASPSLNPPQPSLTQSQYPPQSDQFSSSSSQFCPLPDNSPDLLESLDCLHLQPPIMITPQDAPDQAPPHHFQSSSGQLAPLLTPKEQQAAAASANVVLGRVPARSLQTSVPLVENLPFSPHCRAETTDRNNEDLSDDDTPTLQSRLRKQRKLCFNSRQVDPSVKEGMIKDQLQNDLTRESQLSGSNNGCQTLPKLLGKTLQRNTECPDCGRILSNASALENHMRLHTGERPYTCSQCGKAFPSVRGLNRHMKVHAEEKRYQCEECGKSFVYHFTLTKHQLIHSGERPFPCKVCGKRFLAKADRSTHMRMHTGEKPFSCTLCGKRFKHRVALNMHMQGHRGEKRYTCPHCEKGFVDLGNFKRHKLIHTGERPFECKECGKRFTQSAHLKKHLHTQHGT
The following text describes a protein:
Function:
This protein is a component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system.
Miscellaneous:
MISCELLANEOUS: The MetNIQ system is also to be able to transport the toxic methionine analog alpha-methyl-methionine.
Subcellular Localization:
Cell membrane; Lipid-anchor.
Sequence:
MAFKFKTFAAVGALIGSLALAGCGQDEKDPNHIKVGVIVGAEQQVAEVAQKVAKEKYGLDVELVTFNDYVLPNEALSKGDIDANAFQHKPYLDQQIKDRGYKLVSVGKTFVYPIAGYSKKIKSLDELKDGSQVAVPNDPTNLGRSLLLLQKVGLIKLKDGVGLLPTSLDIVENPKNLKIVELEAPQLPRSLDDAQIALAVINTTYASQIGLTPAKDGIFVEDKDSPYVNLIVTREDNKDAENVKKFVQAYQSDEVYEAANKVFNGGAVKGW