lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Essential for viability. Acts as a suppressor of position effect variegation (PEV) at the white locus and regulates the expression of several unrelated genes. Plays a role in germline stem cell differentiation in the ovaries.
Subcellular Localization:
Cytoplasm.
Sequence:
MANLNFQQPPRSIANAALAGRTTGGFGGSSLAGHVTPTSGMFQTDFANSYPGTANYGQAPQQQQQQQQQPQLSPNRNAQLSVGGPAISSGNRNANLFGQRQFVERRAMQGLGSGPMSNMGNFMQTGRGGYGTGGGGGGPLNNFHVFGGGGGSDTSTPALLDPTEFPSLTNARGQNDQTLPQSNPLQPPGSKPYGNFFTSFGMVKQPTSEQSEFTMSNEDFPALPGTQNSDGTTNAVGSVAGTGGSGGASTENHLDGTEKPMNSIVVSGSASGSSGSNVGVVGGNGLGAVGSGIGGLAVGGGGGAGSSGGGGVGGNAASGVVGGSHVGLVGSNSGIGGVNSVPNSNAMMGVGGGLGSGSGSSGSGAGGEHLNDNSSNDKLVKSGVQTSPDGKVTNIPATMVNNQFGMVGLLTFIRAAETDPNLVTLSLGTDLTGLGLNLNSQESLHTTFAGPFVAQPCRAQDVEFNVPPEYLINFAIRDKLTAPVLKKLQEDLLFFLFYTNIGDMMQLMAAAELHSREWRYHVEEKIWITRIPGIDQYEKNGTKERGTFYYFDAQSWKRLSKVFQIDPEKLDKCPNISAFMNGQSV
The following text describes a protein:
Function:
The carboxylated form is one of the main organic components of the bone matrix, which constitutes 1-2% of the total bone protein (Ref.1). It acts as a negative regulator of bone formation and is required to limit bone formation without impairing bone resorption or mineralization. The carboxylated form binds strongly to apatite and calcium (By similarity); The uncarboxylated form acts as a hormone secreted by osteoblasts, which regulates different cellular processes, such as energy metabolism, male fertility and brain development. Regulates of energy metabolism by acting as a hormone favoring pancreatic beta-cell proliferation, insulin secretion and sensitivity and energy expenditure. Uncarboxylated osteocalcin hormone also promotes testosterone production in the testes: acts as a ligand for G protein-coupled receptor GPRC6A at the surface of Leydig cells, initiating a signaling response that promotes the expression of enzymes required for testosterone synthesis in a CREB-dependent manner. Also acts as a regulator of brain development: osteocalcin hormone crosses the blood-brain barrier and acts as a ligand for GPR158 on neurons, initiating a signaling response that prevents neuronal apoptosis in the hippocampus, favors the synthesis of all monoamine neurotransmitters and inhibits that of gamma-aminobutyric acid (GABA). Osteocalcin also crosses the placenta during pregnancy and maternal osteocalcin is required for fetal brain development.
Subcellular Localization:
Secreted.
Sequence:
YLDHWLGAPAPYPDPLEPRREVCELNPDCDELADHIGFQEAYRRFYGPV
The following text describes a protein:
Function:
Involved in septation.
Subcellular Localization:
Cytoplasm. Cell tip.
Sequence:
MGFHGCLSTDEYEPELIEKYGNPEPPSSSILINTRPVNPFLSTFVYVGKASSSEDVSISTGEEEMRTLLVASAVKDAKGWVYLSGKDVEEIKQKIKNLQGLLGVSIKKLAVEAKIREAAKNLMVAQAKEKKGKHKQSTIEHYEQCSRRVRELSSKIWLIERKLAEFYMHLLKHMVAVCIAELKPGSCSKVSSPVSAITADESATGFRDEEIMNNEEIEQLVERMSRILEIAQSMGNSIREPSVLDAVQMNAGERLLEQVRHLELILKQIYEKKLEEDADAKDIAPRAIVNFWRLLTELFRGDNDTPEKSNALPDDELDKHLKSDFDIESFCFLLHHLLSLYQTQKKELASSNELLASVRDENTKKLKELQDIIEEQSKHMARLHREGFSEAAENNDKPKETMPCTYDSSLADDHSDTSNLSKDKANTLCAQCSVYLSEKYQQQQSLLQLESNIQQLENEKKAAKLIEKDLLSQISHVKLQFEQQIKAHHYAKDQVRNLNDEMVALRAELEVVKAMNSQPDDPDSDYAIKQNNALQNRLEALTRENELLQSRVTTLEMEKEVQEKNSATVSNLTLKQLQMENIFASLNLENSFDFGMPLMGPYTQQNLQLEDEISEISSPSYSSDDDRKTISETQPAPKQNINEEFENSTSTDGSETNKNEQGNSLSTPDNEPRLRKESLSSDVLLDGSEKPAQAELTINSENFPVDCSLPVQTGADVVVPDTTDEEVITSEPVKLEQPINENSNVEEAEKDYQPSEKDDKSLIGGILSTVEMTQSTDVNDEIENTLTIPVEVEHSDNIDKGSEENDLGKEAVDEANNNQNDVLESVVVEQSTTTDDCENKVYEGQMNDKNSSLDMVNACEGINQTAIGFVEKPDKVTELIDEAEENIDISQDISMTETNAVDDEVQAENSILQDEVEETRQDDIEKDELEDIKEVKEDENLTTLEETIEIPANDIEVQDPEQCSCMNSTENDNITTENSSEIVQVIHTEDDSLHFDDNVSTDSVSLGNKSRISMDSMRNDCEAFLPKKEKFGSLRTLHSFESSMRRVSTSAA
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.
Subcellular Localization:
Secreted.
Sequence:
MASALNRGNSLKVPLPKASLLTRTASFPTDSSQRVSGAFQGPAATAPLMRGDTFKAGASTDSASVRWGSMKGAGKMAASTLKLAVLLFIGVYLYGAVSYARSIRYPSRVVTTEMLYRRLEEAGDTVPEHFHLYSCPQATFVVSELVNKFVTTDPNLAGGLEVLQFHDCFVRGCDASILLNSTSATTPEKDASPKADQESLRGFEQIDKIRAALEEACPDIVTCADILALVARDPTLKAGGPSWSVVLGRREGFVFLEAEAKISLPSPLSNFSSLVQNFELVKCTMDETSSY
The following text describes a protein:
Function:
Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
Subcellular Localization:
Cytoplasm.
Sequence:
MSDQPLLVNVETWITENQKAFLPPVCNKLMHFSQLQIMFVGGPNTRKDYHIEEGEELFYQLKGDMCLKIIENGKHKDVHIKEGEIFLLPARIPHSPQRQANTVGLVVERRRLLNETDCLRYFVDNTTDILFERWFYCENLGTQLVPIIKEFMASKQFKTGKPDPNEVFREPPFQLSTMNVMTPFSFKDWLERQRPSLCNGHPIDMFGAQFETEVMVFGPGLTETSVRLTDVWIWQLEGQSRVTVAEQEFSLSAGDSVLIPEQSKYQWQREDGTVALFVVQNPERKRS
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
MKVTVIALLLVIDQAIGATWVYSQGPKGPSNWLNSYAACGTRAQSPISIEHENSVANKNLGTFDRSVFTSLPASMELVNNGHALQVNMDGSYTISDRSVLPNDYKAVQFHLHWAAANKSEGSEHWLNGKQYFAELHVVHYNTKYASIGEAVNKPDGLAVLGVFVDINDETNEHFNLLLNPINRVQIPNQEMTYTSKFSVANFLPTDLSEYYRYRGSLTTPPCFDSVVWTVFKEPIHMSRDQARVLQTSLYDGINSTAKVGGNFRLPQPINGREVSRPYKSGANPIPLPIFLQITAMLAVVKTLYF
The following text describes a protein:
Function:
Likely to be involved with PKD1 in the detection, sequestration and exocytosis of senescent mitochondria.
Subcellular Localization:
Vesicle. Secreted, extracellular exosome. Note=Detected on migrasomes and on extracellular exosomes in blood and urine.
Sequence:
MAPPSRHCLLLISTLGVFALNCFTKGQKNSTLIFTRENTIRNCSCSADIRDCDYSLANLMCNCKTVLPLAVERTSYNGHLTIWFTDTSALGHLLNFTLVQDLKLSLCSTNTLPTEYLAICGLKRLRINMEAKHPFPEQSLLIHSGGDSDSREKPMWLHKGWQPCMYISFLDMALFNRDSALKSYSIENVTSIANNFPDFSYFRTFPMPSNKSYVVTFIY
The following text describes a protein:
Function:
Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MGKLLNLFRDMKVAKKLLISFFVILIAAVSIIGGMSYQTAKKNFESQITSSANDNIKILDNLINQMIEAKFNDVNNFARVIQGNMYQGDNQDELRKTLSQYINLNIDVEQVYVAGNDKKFVQEPNIQMAADYDPTTRPWYKDAVAKQGGIVVSEPYKAKGNGHIVVTIAKQTEDKNGVVALDLSLDNLLKTTKLINIGKKGYAFILDGKQKIIAHPQEKSGDKAADSWAKKIYEDNHGAFTYSYGGSEKNMVFATNVKTGWKIGGTMYATEVIEAAQPVFYNMLIVMLISLVVGGALIYFVTLSITKPLKRLVVTSKEISEGDLTQTIEIHSNDEIGQLAKGFNEMTNSLRTLIGRINDSAGHVAAASEELTASVRQASEATEQITIAMDEISSGATTQTTSVENGAMLLFDVTEGIQHVANSSSSINTASAHTREKAEDGGKLVGRTVNQMQSIAESVSQSDAVIQLLNNKSKQIGDILEVIQNIADQTNLLALNAAIEAARAGEHGRGFAIVADEVRKLAEQSSVSSSEISKLICEIQDDMGKTVKSMNHVNEEVQSGLVIANETKQNFAEILQSTNEIANQIKTMVETANGMSKGANEVSISVGQIAMTAQNNATSTQNVAASAEEQLASMEEIGSAAGTLSQMAEELQGLIDRFKV
The following text describes a protein:
Function:
Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex.
Sequence:
MDQPKYFSSLLGFLLKKEYEKDEDCKSLETLKEMVFSEQDDVTLELIEFTYNKCFEIIQKASYSDMQISTFENIVKESDFTTVQQECLNKFWKVNKKKIHEIIYKTTRFNNSLQKISWRIDVKTKSKEISEINEPVSIVELKLKNTNTNNNNNNKNDLIRFEMDKNQLEETLQQINSIQKHLQAKSL
The following text describes a protein:
Function:
Helps load the DnaC replicative helicase onto single-stranded (ss)DNA and simulates the helicase activity; in the presence of DnaB more helicase activity is seen. Regulates DnaC helicase activity, at low concentrations stimulates the DNA helicase and ATPase activities of DnaC. Has no measurable ATPase activity after 1 hour incubation of 6 uM DnaI with or without DNA. Another group has found the protein has weak ATPase activity that is not stimulated by ssDNA. Whole protein binds forked DNA (but not ssDNA) weakly; ATP and ADPNP (probably 5'-adenylyl beta, gamma-imidodiphosphate) have no effect on DNA binding. DnaB, DnaD and DnaI may be required for a PriA-independent pathway of replication fork restart.
Subcellular Localization:
Cytoplasm. Note=Forms foci near both cell poles and in the middle of cells.
Domain:
The N-terminal domain (approximately residues 1-136, Nd) interacts with helicase DnaC and has a Zn(2+) cofactor. The C-terminal domain (approximately residues 137-311, Cd) has ATPase activity. The ATPase activity of the Cd (not whole protein) is stimulated by ssDNA; Cd has a cryptic DNA-binding site that is masked by the Nd. The CTD binds both ssDNA and forked DNA.
Sequence:
MEPIGRSLQGVTGRPDFQKRLEQMKEKVMKDQDVQAFLKENEEVIDQKMIEKSLNKLYEYIEQSKNCSYCSEDENCNNLLEGYHPKLVVNGRSIDIEYYECPVKRKLDQQKKQQSLMKSMYIQQDLLGATFQQVDISDPSRLAMFQHVTDFLKSYNETGKGKGLYLYGKFGVGKTFMLAAIANELAEKEYSSMIVYVPEFVRELKNSLQDQTLEEKLNMVKTTPVLMLDDIGAESMTSWVRDEVIGTVLQHRMSQQLPTFFSSNFSPDELKHHFTYSQRGEKEEVKAARLMERILYLAAPIRLDGENRRHP
The following text describes a protein:
Function:
Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN.
Subcellular Localization:
Cell junction. Cytoplasm, cytoskeleton. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein.
Sequence:
MRASGGAAMAVWTRAGKAGLVELLLRERWVRVVAELSGDRLSLTGDAAASCSSCSSCPSSNGLPNGTGRGEPGEPGEPGEPDEAGEAEAAGPPPGSPPVRRVRVVKQEAGGLGISIKGGRENGMPILISKIFPGLAAERSRALRLGDAILAVNGTDLRQATHDQAVQALKRAGKDVLLDVKFIREVTPYIKKPSLVSDLPWEGTSPQSPSLSGSEDSGSPKHQISIKDKKVIPLKMCFAARNLSMPDLENRLIELHSPDGRNTLILRCKDTATAHSWFIAIHTNIMALLPQVLAELNGMLGASSVTAGSKEVKHIAWLAEQAKLDGGRQHWRPVLMAVTEKDLLLYDCMPWTRDAWASPCHSYPLVATRLVHSGSGCRSPSLGSDLTFATRTGSRQGIEMHMFRVETHRDLSSWTRILVQGCHAAAELIKEVSLGCTLNNQEVKLTVHYETGFTISREGGGTISVLFRYPFEKLKMSADDGIRNLYLDFGGPEGELTMDLHSCPKPIVFVLHTFLSAKVTRMGLLV
The following text describes a protein:
Function:
Catalyzes the GTP-dependent phosphorylation of 5-hydroxy-L-lysine.
Subcellular Localization:
Cytoplasm.
Sequence:
MASLLSGRGSETHNTMSRENDQKSPLLTKPSFTELQAATLVESIFGLNVSKVKALPSYDDQNFHVHISKDNGTPEELSEYVLKITNSESSKNSDLIEVQSHAIMFLRKEGFPTAALQSTKEGNITFLMTVGCGSETKSYMMRLLTYLPGRPIAQVPATPSILYEIGKVAAKMDKTLQEKFRHPGINNLHRGDFIWNLKNVPLLEKYVHALDGNGNREIVDQVIQQFKDKILPKLNHFRSCINHGDFNDHNILVDVSRASPEDASYHISGILDFDDMSYGYYVFEVAITIMYMMIESKDPLPVGGHVLAGFESIVPLTAEERDALFLLVCGRFSQSMVMAAYTCLLYPENKEYLMITAKTGWKHLKQMFGMGQKAVENIWFEIAQSYSPEKPV
The following text describes a protein:
Function:
Probable adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases.
Subcellular Localization:
Cytoplasm.
Sequence:
MNNNPIIKNYKKSLSQSFDDLLVNKDIDDSFTCPICLKLLIDARQGCSEGHVFCNNCITSWLKNKNNCAVCRLHISQNCLSKNRFLESNIKKIKVFCPNKNDLNDLNDDSDGCPEILEIGNVESHSLKCIHRFVLCQYGGDKCGPVRLNKLLSHEIECPFVEIQFENSKKTNSLKKKKNFRFQIPNSPQ
The following text describes a protein:
Function:
Putative oxidoreductase.
Sequence:
MDLSAVNPLIAAGALAVPIGAYALVQLARLAVPGPHRQARFNFKDKTVLITGASTGLGAALARELYTRGARLILVARSIDKLKALCESIKESGPGHEPVYAYLDLAEPEKVDELVKLSHNGKIDCLVNNAGISMRGSVIDTDMAVQRKVMETNYFGQVAVTRALLPFIPSDGAIVVTSSMQGKMALPYRSAYGASKHAVQAFFDSLRAEERFGLHILVVSAGYIATELGNNALDASGRPTGVTDGNVGNGLKPEEAARQIANATERRKPELLMAPLLHRFTVFLRYWWPSLYFYSVWKRHIMQEAKEKKKE
The following text describes a protein:
Function:
Binds in decreasing order of affinity: galacturonic acid, D-galactosamine, methyl-alpha-D-galactopyranoside and further galactose-containing carbohydrates. Has hemagglutinating activity against human and rabbit erythrocytes.
Sequence:
DPDKCKTIRVESWSYKYAEKVVEDASYVLNMTVVDRQSAAACTLGESFGYQKATLWVDHGCRADFKVCYLPVMPTECQTLRVESWNYKYAEKVVEGAALFINMTVEDRQSEASCDLDKSFGFYNQNSTVWVNHGCRADFNICYLKGAVTTSTINVSSWNYQYATKVLPAASCIYSMRVVNQQSAAPCTLGTTYGFVANTMWVDDGCRADFKPSYYSP
The following text describes a protein:
Function:
Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.
Subcellular Localization:
Mitochondrion.
Sequence:
MREIVTITASHRANHLITQFFNGQERALHERDEQAGSDPSVFLHGTIDADGRTMSYEPRAVLWDAKGGSGALGRFQYWSQDDYADEEEPPRAAPGIEVVQTAARVRRSAYQRALDAGEAPPALTAAGARYWSDYGRMIYGQDSVQELAHWHHDVAAPSAPDFEALGQRRFDRYENGYEVFTEECARDFFDISLHRQLEQCDTLQGFNLVTETDNGWGGFMAALQEQLREEVPKVCYFGWGLNVDESGPRHPPRAGFQRQSNKLRATLAMLEQSDLYFPIRSEAADSLWEAGGWACHVLDSVNSAMCLEKSRTLRFMNQLADRLHSGDEQRNVVSLMSSGQRSYSYFADAPRHRSSRGDPHTFSRCRLLRGSHSPPETTLSVENLELIRTYAWRPADTIPETARNLHHIDLGVTEKCRDVFKNWYEMVAKQFRYDPDREELKERLGTLGAAYECGWYSDDDSGDDT
The following text describes a protein:
Function:
Involved in cell wall biogenesis. Has a role in the addition of Gal-beta1,3 moeities to galactomannans and their subsequent pyruvylation. Has a role in meiosis.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Note=Recycles between endoplasmic reticulum and Golgi.
Sequence:
MTKLWVNFFSQKLLRLLIPSIIVVFAFAALFAIYSPIQLGGINFYKRTNLFTVEELGEKELELSKTVTIDIYRKAMCMDDLEQSRKCTTFGLDPPISAHLFYTYNRDTGMNRVARQWNRRIPRVFHTIKGSNFIELSQFTAFEVELRVSHPNWAFVSWSHDDLNELVDKSYHNLHNAWSQLSREAKDQWGFLLGLYEYGGVWMSRSLQLKKNIDKFVYAAELSVKQFTENITSSTVEEFQPIFMAPKSLQYDFMIATPKHPFVLSLINELCKSEVLLKILSKRPYHGLDAAEALFAENRESITIREQEFFVNTYIDDGKVFVKNNPHIIFIPTEAFASTWDFLPSEESSEMCFADSPLFDPDYCISHSSKPDGNELAIYWSNSFDLITA
The following text describes a protein:
Function:
May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact, is not able to exhibit diacylglycerol kinase activity in vitro.
Sequence:
MSHRKALLIHNGNAGNKNIEKALGAVVPVLSHHLDEVIIKQTKKKDDAYHFCRSIDDSVDTVFILGGDGTIHQCINAISALERKPAVGILPGGTCNDFSRVLGIPQNLAKAAEALMAGKKTSVDVCQMNDRYFLNFWGIGLIAETSNQINETEKALLGKISYFTSALRTVSSAASFPMTLKIDGEEIKEEAVMLLVMNGQYIGTNRIPLPDASIEDGLLDVLICRNTNLTALRELMSMEQGSIDRFTGELSYVQASRIEIETDTAKKADMDGEVYTHTPAVIQVLPQHIDMLVPANE
The following text describes a protein:
Function:
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.
Subcellular Localization:
Nucleus.
Sequence:
MSKQPTNPLMRSKKYDSPLRRDRPSLRPQMRKGPINIPARPGHKFIQSTPGVKKEENEPKYKEYSLVAASKDELKDLRYHIMRLHSIKNVDPGADFTPPIKLHRKDPRNLQFQATQEEQAAESNADSGAEEGTEPVKREQADLSKIAPDGGARHAKKNQFNKKAKQVIHRDEDAKKLRYEEYYPWVMEDYSGKNTWVGNYEAAQSDSYCVFVFHGNGFKMVPVEKFYKFTPRNQYATLTLEEAEKRMADSVKAGTPRWLMKHMSPEMQQSRMRDQRPRKFQTVDSGGPVDDDDGLSRRRERDDEDLDFDHVFDDDEEAPIMDGDEEDQKEVERKMKNEHRSAAVLKDDNHDDMGDLFGEEEEEKMDKEGRKLKKYLRSLEKNAHYDSDDDENPYASSSEDDDDEEDGIKKEDPVKKEEDLAIKEEPMPLFVKKNITGLPRGMAVIQLPPHVLAKFTRGVWNPNAKRPREAGGESGDAKRPRTADADLPPPFGPNDTVLSDDIILNTLRSRPPMAVQDLLRILMPIMRKDADNKARLTACLKKHAKVQNGVLVLRE
The following text describes a protein:
Function:
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
Sequence:
MAELNHECGVAAIYHLSGRGRSPVCTDDGPRQISRLLPRMLLDIQNRGQLAAGMSTFDPDRPALLKTRRDVGTVTEVFRLNHRAKAESLMKSLAGRAAIGHVRYATCGADDRNYAQPFERRHIHKRKWFSFCFNGQLANYTLLKQRLLADGDHHLALDTDTEIILHEIARLLSQSQERVDWIDVLKQVTAGFDGAYSMALLTAEGEMLVARDPLGIKPMCYIHEGPLFACASESVALLNLGFEPDQIRSLPPGHAILIDPDEGFRMERFAEPETPKHCFFEWIYFANVASTLDDRSVYLSRTNLGRELATAEREFGRVPLDDPDTIIVPVPDTSKAAADSMAYELSIPCREGLIRNRYAGRTFIEGGRARKAKAAAKYTPLREVLQGKRVILVEDSIVRSTTMNALLDRIRDVGGAKEIHVRVACPPIVAPCFYGIDMSTIDQLIAPKYFSLTGELDEESQQRMADDLGADSLQYLPVSAIARAINLPEEHLCQACVTGKYPTPIGQHLYQIACDNRGARVNNQRTYEQLAAAVAGQ
The following text describes a protein:
Function:
Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.
Subcellular Localization:
Nucleus.
Sequence:
MSEQAEPQVSQILPLELVDKCIGSKILVLVKSKVEFTGTLVGFDDFVNMVLEDVTEVNTKTGKETNHSKLLLSGKSIYMLVPGGL
The following text describes a protein:
Function:
Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity).
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MATRKRNEWLDAAESDDDERGYDSEEESRARMLPSAKRQKRDHDSEDEEDAEDQEEDVDQDDKEDDEDDEDDEDATDDIPKTAELAHLEKLAAGLPSNLKLQTTKLGKPVAPKKDKSGVIYLSRVPPFMKPTVLRSLLTPYGAVGKIFLTPEPAASRTQRLRGGGTRRKLFLDGWVEFLHKRDAKFVADNLNAQTMGGKKRGRWHDEVWNIKYLSGIKWNHLVETIQNENAERAARMRVEISRGKSENKAFLENLEMGKMIQGIEAKKKEKEDRGDDGEGMKAAEQVVEKKVKKPRREFVQHGVTSKGAKKPEPGQDVNRVLSSMM
The following text describes a protein:
Function:
May only reduce GSH-thiol disulfides, but not protein disulfides (Potential). Probably involved in the regulation of the redox state of the BOLA proteins (Potential). May act as Fe-S cluster donors to Fe-S cluster-requiring proteins. May protect cells against protein oxidative damage. May regulate CAX cation transporters. The GRXS14-BOLA1 heterodimer binds a labile, oxygen sensitive Fe-S cluster.
Miscellaneous:
MISCELLANEOUS: The GRXS14-BOLA1 apo-heterodimer model derived from NMR data shows a domain arrangement totally different from the holo-heterodimer showing evidence for a Rieske-type ligation of a [2Fe-2S] cluster.
Subcellular Localization:
Plastid, chloroplast.
Domain:
The C-terminal region (79-168) is involved in BOLA recognition in GRXS-BOLA apo-heterodimer.
Sequence:
MALRSVKTPTLITSVAVVSSSVTNKPHSIRFSLKPTSALVVHNHQLSFYGSNLKLKPTKFRCSASALTPQLKDTLEKLVNSEKVVLFMKGTRDFPMCGFSNTVVQILKNLNVPFEDVNILENEMLRQGLKEYSNWPTFPQLYIGGEFFGGCDITLEAFKTGELQEEVEKAMCS
The following text describes a protein:
Function:
Transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MGRPPCCDKVGIKKGPWTPEEDIILVSYIQEHGPGNWRAVPTNTGLLRCSKSCRLRWTNYLRPGIKRGNFTPHEEGMIIHLQALLGNKWAAIATYLPQRTDNDIKNYWNTHLKKKLKKLQLPPFEAPPPPQIAASSQDSTFYRQFISKSYNGAERIIDNNHKVVVSENSS
The following text describes a protein:
Function:
Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
Sequence:
MAQNQGNCSCSPSNSSGKPRKVALITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSFNTGRIEHLYKNPHAHTEGNMKLHYGDLTDSTCLVKIINEVKPTEIYNLGAQSHVKISFDLAEYTADVDGLGTLRLLDATKTCGLINTVKFYQASTSELYGKVQEIPQKETTPFYPRSPYGAAKLYAYWIVVNFREAYNLFAVNGILFNHESPRRGANFVTRKISRSVAKIHLGQMESFSLGNLDAKRDWGHAKDYVEAMWLMLQTDEPEDFVISTGEVHSVREFVEKAFKHIGKTIVWEGKNENEVGRCSETGKIHVKVDLKYYRPTEVDFLQGDCSQAKNKLGWTPKVSFDELVKEMVESDVKLMATNPNA
The following text describes a protein:
Function:
May have a regulatory function possibly in association with the Notch gene product.
Subcellular Localization:
Nucleus. Chromosome.
Domain:
The protein has many AA homomeric domains: 21 poly-Gln runs (from 5 to 16 AA in length), 4 poly-Gly (6 to 10 AA), 3 poly-Asn (3 X 5 AA), 1 poly-Ala (10 AA) and 1 poly-Thr (5 AA) runs.
Sequence:
MDAGGLPVFQSASQAAAVAQQQQQQQQQQQQHLNLQLHQQHLGLHLQQQQQLQLQQQQHNAQAQQQQIQVQQQQQQQQQQQQQQHSPYNANLGATGGIAGITGGNGAGGPTNPGAVPTAPGDTMPTKRMPVVDRLRRRMENYRRRQTDCVPRYEQAFNTVCEQQNQETTVLQKRFLESKNKRAAKKTDKKLPDPSQQHQQQQHQQQQQHQQHQQHQQAQTMLAGQLQSSVHVQQKFLKRPAEDVDNGPDSFEPPHKLPNNNNNSNSNNNNGNANANNGGNGSNTGNNTNNNGNSTNNNGGSNNNGSENLTKFSVEIVQQLEFTTSAANSQPQQISTNVTVKALTNTSVKSEPGVGGGGGGGGGGGSGNNNNNGGGGGGGNGNNNNNGGDHHQQQHQQQQQQQGGGLGGLGNNGRGGGPGGMATGPGGVAGGLGGMGMPPNMMSAQQKSALGNLANLVECKREPDHDFPDLGSLDKDGGGGQFPGFPDLLGDDNSENNDTFKDLINNLQDFNPSFLDGFDEKPLLDIKTEDGIKVEPPNAQDLINSLNVKSEGGLGHGFGGFGLGLDNPGMKMRGGNPGNQGGFPNGPNGGTGGAPNAGGNGGNSGNLMSEHPLAAQTLKQMAEQHQHKNAMGGMGGFPRPPHGMNPQQQQQQQQQQQQQQAQQQHGQMMGQGQPGRYNDYGGGFPNDFGLGPNGPQQQQQAQQQQPQQQHLPPQFHQQKGPGPGAGMNVQQNFLDIKQELFYSSQNDFDLKRLQQQQAMQQQQQQQHHQQQQQQQQPKMGGVPNFNKQQQQQQVPQQQLQQQQQQQQQQQQQQQQQYSPFSNQNPNAAANFLNCPPRGGPNGNQQPGNLAQQQQQPGAGPQQQQQRGNAANGQQNNPNAGPGGNTPNAPQQQQQQSTTTTLQMKQTQQLHISQQGGGAHGIQVSAGQHLHLSGDMKSNVSVAAQQGVFFSQQQAQQQQQQQQPGGTNGPNPQQQQQQPHGGNAGGGVGVGVGVGVGNGGPNPGQQQQQPNQNMSNANVPSDGFSLSQSQSMNFNQQQQQQAAAQQQQVQPNMRQRQTQAQAAAAAAAAAAQAQAAANASGPNVPLMQQPQVGVGVGVGVGVGVGVGNGGVVGGPGSGGPNNGAMNQMGGPMGGMPGMQMGGPMNPMQMNPNAAGPTAQQMMMGSGAGGPGQVPGPGQGPNPNQAKFLQQQQMMRAQAMQQQQQHMSGARPPPPEYNATKAQLMQAQMMQQTVGGGGVGVGGVGVGVGVGGVGGANGGRFPNSAAQAAAMRRMTQQPIPPSGPMMRPQHAMYMQQHGGAGGGPRTGMGVPYGGGAGGPMGGPQQQQRPPNVQVTPDGMPMGSQQEWRHMMMTQQQTQMGFGGPGPGGPMRQGPGGFNGGNFMPNGAPNGAAGSGPNAGGMMSGPNVPQMQLTPAQMQQQLMRQQQQQQQQQQQHMGPGAANNMQMQQLLQQQQSGGGGNMMASQMQMTSMHMTQTQQQITMQQQQQFVQSTTTTTHQQQQMMQMGPGGGGGGGGPGSANNNNGGGGGGAAGGGNSASTIASASSISQTINSVVANSNDFGLEFLDNLPVDSNFSTQDLINSLDNDNFNLQDFNMP
The following text describes a protein:
Function:
Is required for normal leaf, flower and seed development and controls cotyledon and leaf patterning by inhibiting premature differentiation. Regulates the expression of a subset of PcG target genes. Is required for the repression of the floral specific genes PI, SEP2, and SEP3, but also for the activation of FLC. Involved in response to cold. Involved in the regulation of COR15A, COR15B, BAM3 and AMY3 transcripts, and ascorbate levels in response to prolonged chilling temperatures.
Subcellular Localization:
Nucleus. Cytoplasm. Note=May shuttle between the nucleus and the cytoplasm.
Sequence:
MASATSSRRQEDVEAGRRKLEQFRKRKAAEKAKKASQNTQPVDNSQQSVIDSDGAGASISNGPLKQSAESTSNETHTKDVYNLSFSNTAMDDGSKERSRQDDGQESVGKVDFSNSLELIGSSKDLTVNTRPEVVPYSNIDKQSSESFDRASTLRETASLFSGTSMQMDGFIHGSGLTSSRKDSLQPTTRMAGSFDEVAKNQQGSGELGGSIVQKPTLSSSYLFNSPDTSSRPSEPSDFSVNITSSSPLNSAKSEATVKRSRPSFLDSLNISRAPETQYQHPEIQADLVTSSGSQLSGSDGFGPSYISGRRDSNGPSSLTSGASDYPNPFEKFRSSLYPAANGVMPGFTDFSMPKQNDDFTALEQHIEDLTQEKFSLQRDLDASRALAESLASENSSMTDTYNQQRGLVNQLKDDMERLYQQIQAQMGELESVRVEYANAQLECNAADERSQILASEVISLEDKALRLRSNELKLERELEKAQTEMLSYKKKLQSLEKDRQDLQSTIKALQEEKKVLQTMVQKASSGGKSTDLSKNSTSRKNVSTSTEGLAISDTTPESSNQETDSTTLLESDSSNTAIIPETRQLTLEGFSLSVPADQMRVIHNINTLIAELAIEKEELVQALSSELSRSAHVQELNKELSRKLEAQTQRLELVTAQKMAIDNVSPEKQQPDTHVVQERTPIADEGDEVVERVLGWIMKMFPGGPSKRRTSKLL
The following text describes a protein:
Function:
Regulates the function of the receptor protein kinase WAK1, and namely the phosphorylation of OEE2.
Miscellaneous:
MISCELLANEOUS: GRP3 and GRP3S bind to WAK1, WAK3 and WAK5, but GRP2, GRP4,GRP6, GRP7 and GRP8 did not bind to any of the WAK isoforms.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Domain:
The Cys-rich C-terminus (111-145) is essential for the interaction with WAK1.
Sequence:
MASKALVLLGLFAVLLVVSEVAAASSATVNSESKETVKPDQRGYGDNGGNYNNGGGYQGGGGNYQGGGGNYQGGGGNYQGGGGRYQGGGGRYQGGGGRYQGGGGRQGGGGSGGSYCRHGCCYRGYNGCSRCCSYAGEAVQTQPGH