lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity).
Subcellular Localization:
Cytoplasm, nucleoid. Note=Localizes in tight foci to the chromosomal replication center at mid-cell; targeted to the nucleoid via the 6 C-terminal residues of SSB (ssbA).
Sequence:
MSFVHLQVHSGYSLLNSAAAVEELVSEADRLGYASLALTDDHVMYGAIQFYKACKARGINPIIGLTASVFTDDSELEAYPLVLLAKSNTGYQNLLKISSVLQSKSKGGLKPKWLHSYREGIIAITPGEKGYIETLLEGGLFEQAAQASLEFQSIFGKGAFYFSYQPFKGNQVLSEQILKLSEETGIPVTATGDVHYIRKEDKAAYRCLKAIKAGEKLTDAPAEDLPDLDLKPLEEMQNIYREHPEALQASVEIAEQCRVDVSLGQTRLPSFPTPDGTSADDYLTDICMEGLRSRFGKPDERYLRRLQYELDVIKRMKFSDYFLIVWDFMKHAHEKGIVTGPGRGSAAGSLVAYVLYITDVDPIKHHLLFERFLNPERVSMPDIDIDFPDTRRDEVIQYVQQKYGAMHVAQIITFGTLAAKAALRDVGRVFGVSPKEADQLAKLIPSRPGMTLDEARQQSPQLDKRLRESSLLQQVYSIARKIEGLPRHASTHAAGVVLSEEPLTDVVPLQEGHEGIYLTQYAMDHLEDLGLLKMDFLGLRNLTLIESITSMIEKEENIKIDLSSISYSDDKTFSLLSKGDTTGIFQLESAGMRSVLKRLKPSGLEDIVAVNALYRPGPMENIPLFIDRKHGRAPVHYPHEDLRSILEDTYGVIVYQEQIMMIASRMAGFSLGEADLLRRAVSKKKKEILDRERSHFVEGCLKKEYSVDTANEVYDLIVKFANYGFNRSHAVAYSMIGCQLAYLKAHYPLYFMCGLLTSVIGNEDKISQYLYEAKGSGIRILPPSVNKSSFPFTVENGSVRYSLRAIKSVGVSAVKDIYKARKEKPFEDLFDFCFRVPSKSVNRKMLEALIFSGAMDEFGQNRATLLASIDVALEHAELFAADDDQMGLFLDESFSIKPKYVETEELPLVDLLAFEKETLGIYFSNHPLSAFRKQLTAQGAVSILQAQRAVKRQLSLGVLLSKIKTIRTKTGQNMAFLTLSDETGEMEAVVFPEQFRQLSPVLREGALLFTAGKCEVRQDKIQFIMSRAELLEDMDAEKAPSVYIKIESSQHSQEILAKIKRILLEHKGETGVYLYYERQKQTIKLPESFHINADHQVLYRLKELLGQKNVVLKQW
The following text describes a protein:
Function:
GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
Subcellular Localization:
Cytoplasm. Note=May associate with membranes.
Sequence:
MMEEKEKVILVGCQLPQDDDEKFMHSMKELASLAKTARAELLVSTTQKRPKFHPATYIGKGKLEELTMLTEELEPDVIVFNNELTPSQIRNLSSVLDARVIDRTQLILDIFAQRAKSREGKLQVELAQLQYTMPRLMGQGLSLSRLGGGIGTRGPGETKLETDRRHIRSRIDEIKKQLAVVVEHRKRYRERRKDNKVFQVSLIGYTNAGKSTLFNRLTEADTFEENLLFATLDPTTRKMPLPSGYTVLLTDTVGFIQDLPTSLIAAFRSTLEEAGEADVILHVVDSADPNYIGHEKTVKRLLSELEINHIPIITLYNKKDELHQNFIPFPKSDFLMTSAFEESDVLRIKEAIEMKMKKEMDRYRVEIPPSEGKLLTLLKTETLLAKMEFLEDKFVYDCAGYIFTHSSLNVQLKRFLVEEGENKNV
The following text describes a protein:
Function:
Plays a role in pre-mRNA splicing by facilitating excision of a subset of introns (By similarity). Involved in the regulation of G1 progression and stage differentiation of tachyzoites. May play a role in gene expression.
Subcellular Localization:
Nucleus. Note=Localizes in the nucleus throughout the entire tachyzoite cell cycle.
Sequence:
MGKKRRKHDGSGSSRSPSPDRIREARNPSQAEVAGFRAPPSGKPAMTVKQLREERQKLLHEHFGYSNTNNPFGDRLLAEPFVWKKKNQLLQAAGQKGKTTVAALIHSSKSKVQEIENVKRRREEREKEEELMQQQREELQREKEREHYEEYAQKEELFHRSNQLKKTEIRLEQNRAQLIDLIVKGLRIIKGERFEKMDVLPGPPHEVLETYKNEPVTVAMLEDLIADVKLHIDVDTTVVDADFQDFWKSLLVLAREALERAKKRKDVLDQLARNSSPQMAAEAAAQLADTVCPQIRDADTGIVLSVAHEIEGLLGGKSAAELDELEAQIRSKFEEEDIDVAYWEGILNKIPSFRARAVCLQTWHMMTQSAADAEREMAREKALKEEEEAKAARAKGEELEGLLLEEADARKLARAQQIKQDAIKVARSVEKDVNPNADGSFSPELEPYDEGEVPPPVRGPYSPQLWPFDEFRHAEILAPDDDEDRRAILKKTLIQKERLKRAGLEEDPEPTPEAAENDASLDVLDPAAKVTTYEEFVKKEKKNLEADEEVMASSSEHKLTMHYTWEEKYRPRKPRFFNRVKTGYSWNKYNTTHYDHDNPPPKVVQGYKFNIFYPDLIDKTKAPTWFLEPSDTPDTVIIRFHAGPPYEDIAFKILNQEWQLERFRGFRNVFDRGIMQLYFSFKRYIYRR
The following text describes a protein:
Function:
Associates with the striatin-interacting phosphatase and kinase (STRIPAK) core complex, forming the extended (SIKE1:SLMAP)STRIPAK complex. The (SIKE1:SLMAP)STRIPAK complex dephosphorylates STK3 leading to the inhibition of Hippo signaling and the control of cell growth. May play a role during myoblast fusion.
Subcellular Localization:
Cell membrane, sarcolemma; Single-pass type IV membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MVLVCNEWLKNNVDEDQTSSSLSPTPASGAVGSTALNRTGTTDTATELPQTTRYPSGEEPAVKPEEAQYALNMETEKNLEQDNFFHIMDIKEDMADSNNEASTKNQENNNMELCDSNTVCIDRRPAEVSQHAMNMAMNSVLNANNTGVGVRVTTACSLFSPLGVLNNSALQREVASECGTLQVSSVPPTSGVDLDIGLESAPTPCKGAAKIVLLCEPKSHKFETRSILLQPNQDCKVGRLIAKSKAGEGNAIFDCKVLSRNHAILWYTPDGKFWVKDTKSSNGTFINDNKLGSDPAELHYGDIVKFGVEVIENSRQEVHGCILARVALFLPNGQEAISVEAEQMMLTVPNRISFDEVQRLSSFLQEAAQREKSLKAKLSSLQGVLDNTRKNSAMCWQSMITEDQLLHKINILEKKLQMMEKNIPENALRNEIVKLLEDKTTYQLTAKEALRKVYQERCDAMQMLSKMEMAYATSENECGILRAQVLTLKQTLTDFNTRLEELQQEYMEFKKESVRQEQEAKEQESRSLEVLNGKLTTQELELKELRLQVSRIHRDLSESDTEHLKERIVLKNLDTINLDDYDHAQDRALNERDDNESSDDDILSVSPAKNVLSETKKRKLKLSNPDLEEGNYKSNVLRLLKNSDLGKGEEGSSVLKAIFNGDDEAFECKVKEEEDMANDSVPTEFVSRNTSEIVDHFKNHSSTTHTILEDSAATKLSAPNAESKEKLVDVEENLNIPNALPTEQAIDMLQEECDTYKKKTAHLTSEIHFLQGQIELLKKQLEKGVDHNFATNLQEEENSLPRETLELIDNRDSTEGVWNEDIATINNPNVENEEELIVYKELLENSELNNMQLRKEISELHLKHKHIPFSKQELLCRFLPLGCVAIGLLIYFLSSRI
The following text describes a protein:
Function:
Participates in the second step of pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MDFLKEEIERKRRQLEGTSELPVKKAFRRGDWEKEREKKYLQEKQQKDEQRELKKRKLEEERLKYEEKKLRISRLANKESSRNEELLTETTTPSPAVKASPASTKLSVSENDRLSIPEITKDNLTLTEIIAKLREMKEPIRLFGESEEATIQRYYSLLKYKKLEEIENELLTKGVETIDFEHATTTKPKVSKQVVAFLQHGIRIWDNFLSSKSINSFESSESQMQLKIFRQAKQDLDVLIQLIVDEALNDDIFKSIAEICYRCQKHEFVKANDMYLRLTIGNAPWPIGVTMVGIHERSAHQRLQANPSSNILKDEKKRKCLQALKRFITFQERESSNLPEYTD
The following text describes a protein:
Function:
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
MAGDKAQLIKQNEQLRIHANLQRVPVSQSAADMKAYIDSHIQSDPLVNPVDKKDNPWADKSKCTLL
The following text describes a protein:
Function:
Pair-rule protein expressed in a segmentally repeating pattern to define the polarity of embryonic segments. Capable of sequence-specific DNA-binding.
Subcellular Localization:
Nucleus.
Sequence:
MTVTAFAAAMHRPFFNGYSTMQDMNSGQGRVNQLGGVFINGRPLPNNIRLKIVEMAADGIRPCVISRQLRVSHGCVSKILNRYQETGSIRPGVIGGSKPRIATPEIENRIEEYKRSSPGMFSWEIREKLIREGVCDRSTAPSVSAISRLVRGRDAPLDNDMSSASGSPAGDGTKASSSCGSDVSGGHHNNGKPSDEDISDCESEPGIALKRKQRRCRTTFSASQLDELERAFERTQYPDIYTREELAQRTNLTEARIQVWFSNRRARLRKQHTSVSGGAPGGAAASVSHVAASSSLPSVVSSVPSMAPLAMMPGSLDPATVYQQQYDFYGSHANISVSAAAPMASSNLSPGITTTPPHHHQFYNPSANTASYIMPGENGNTTPTGNIIVSSYETQLGSVYGTETETHQTMPRNESPNESVSSAFGQLPPTPNSLSAVVSGAGVTSSSGANSGADPSQSLANASAGSEELSAALKVESVDLIAASQSQLYGGWSSMQALRPNAPLSPEDSLNSTSSTSQALDVTAHQMFHPYQHTPQYASYPAPGHAHSHHGHPHAPHPHAHPHPQYAGAHPHYPPPSSSAHFMPQNFNAAAFPSPSKVNYTTMPPQPFYPSWY
The following text describes a protein:
Function:
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Interacts with beta-1 and beta-2, but not with beta-3.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
MASGASVLALQRLVEQLKLEAGVERIKVSQAAAELQRYCMQNACKDALLVGVPAGSNPFREPRSCALL
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope.
Subcellular Localization:
Cytoplasm. Nucleus, nuclear pore complex.
Sequence:
MDDISATTIQTNHQDLVNDVTYDFYGRRMVSCSADQRVKVYDFNDDTETWAITSEWRAGDASLMRVAWAHPSFGQVLAVCSLDRGVRIYEEQKKNFESKTWVEVAKLMDARSAVLDISFCPFQHGCKLAAVSADATLRIYEAMEPGNLTYWTLMNEIALMPSPPSRNEQPAFCVNWCPSRWREQYIAVGCMNDAYIYKQNSHGKWKKVAELPGHTDLIRDICWAPSMGSSYYLIATACKDGNVRIFKVETLCEEVFQEEEDAGNSMTEDSNFNLNSLKVELIGEYDNHKCQVWRCRFNVTGTILSSSGDDGCVRLWKASYANLFKCISVVSLEKKPEKL
The following text describes a protein:
Function:
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. LAGE3 functions as a dimerization module for the complex.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSDDGASSDEEVQRELSLKHSIELRLDLESPEKAKVVCETLSVDKEPKRSNAVRELRQDGQFLLITVRSEDRRSLQKCTANILDMCDLSMSTLDMAIGKKWLVEPPKKKEKTDNSYGQAPTGMFKGLKSKLEDGAKKAAANVQAAASQYGEQLSQQFRDISANASDAGSDAGSTVGRRFFGANDSGSMNYSVGNALMEEVTDADLLDLDLPGTRQRRDSGGSTHSNESSLSALFASVPGLVGSGGLDTIDSDMESVTDGDIGFVQRTPREQGYKNRYVDLVKKYNQVVTENNKCRTILQQSQDKAINRIRKLKEEKRILSERMNEMHANGKSEESAALEARAAKYEELLEKAKAEIVKNRKELASITEECNVLKESMKDGNPEQALSELAANRVAAEWKERFEKVEEQWTERLNKAEQDAAITLATVKAEMHAALEGKDREIDVLRSKCRTLEVQDGQANERWQKKVDELKASCTALETEKETMIEKLSEAKAQGVKAVLIEEEAKRDALKAEMVEEKRKLSEECDERIREMEKEVERKIEELKAQLASSMSLRSSADDEKKKSEIEEKMEDAQREMRELREKLRDEEEKRTKQVAELEEAIEAQLQRGRTEMAEMIKEHEEILASSREQLEAQLRTANEKSDLNRVEAVQLRTMNEDLQRQLKGCEEREKREEAGRKGEMVELESELSTTRASLAEIEGRMEEMQKDLSESRIRESSSRQEADELADRLEELRGRAEENEERLAASSARFNEELSQLKEMIEERNGTVKRIEEEKENLEAELASAIELSAMHEHLRKQLEDAIESRKEAECRILEIERRAEKAEKELEEDRKRMEEETREREKRMEALPVQSSPSIPHSESLIDMGTDEETIQPSLVSVLASSPVTASSPTASTPIGDTVVSVSHSMEDEWKSAVEDGKDEEMQLLRAQLKQAEERVAALVADLTVERETRTKLEEEIKPLSLQLTELSVQLDAARDTSSGETNILRAQLSELQAENEDLTRRFLDAAADASSFESDAKDWADQVGKERDEARKLAERVSVAETYAREASDRAAKAEAALEAAEARAAMAAAEVKEVEETATEAETRATKAERRADEAEERLKEEREKKGGEDEKERAALRAQVKETESRVVAAESRASEADERALAAEDEKKKMEKRLEECEKEKEVVAKRAEDFESRCSDLLHTLEEARGEKSEVEKRVKILEEESQKKEGEREVSQGKEAELETERRRAADADTRYERLRVEFIAKASTEKMISDLRAEAESLSTRVREEEEKTREAERKMVEKEKEYLRDANSMEEELNKLKKQIEGEMIERAKKDEEEKKIRDQYACALEKLRSEVEEGKRREEEQEKEKEEGMKRLEEMERVKNEIQEKIEGVEQAHSAALEKERKRGEELREKAVRSAEGEWTAAKAEMLMEADSLRASIRSLEKEMDEGRVQRAQMEQKIADAEMERDTADRKRAEREESALRVEKTLKDEVEELKGKISGLESERGEEIKKAAAKQDNERQKIVKELQKEVKQLYSELNEKQQLLEEARQRIRGLEEWQNGEEEEEKAEEKRVSSTQAAAAAAAPAPGDAVGAEELASMRSRLEEARKEADEKGEMIDKMKKQLESKEKVKPQRSSASDYDGLSFAEPTEAEYLRNVLYRYMAERETLGKEIVTLARVIGTVAKFNHQQLEAVISAEESRTAGWLPVTGVSHGRH
The following text describes a protein:
Function:
Catalyzes the NAD(+)-dependent conversion of homoisocitrate to alpha-ketoadipate.
Miscellaneous:
MISCELLANEOUS: Present with 19079 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MFRSVATRLSACRGLASNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYAGFQTFQETGKALPDETVKVLKEQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEGEKGKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQTRGQATLTVTHKSNVLSQSDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHGSAPDIAGKGIANPIATIRSTALMLEFLGHNEAAQDIYKAVDANLREGSIKTPDLGGKASTQQVVDDVLSRL
The following text describes a protein:
Function:
Sinapine esterase that catalyzes that hydrolysis of sinapine, releasing choline and sinapate. Sinapine (O-sinapoylcholine) is the predominant phenolic compound in a complex group of sinapate esters in seeds of oilseed rape (B.napus). Sinapine has antinutritive activity and prevents the use of seed protein for food and feed. Shows broad substrate specificity towards various other choline esters, including phosphatidylcholine.
Miscellaneous:
MISCELLANEOUS: Overexpression in seeds induces a strong decrease of sinapine levels together with an increase of choline. Seeds display higher weight, size and water content and a fraction of seeds display morphological alterations, characterized by large cavities near the embryonic tissue. Seed quality parameters, such as fiber and glucosinolate levels, and agronomically important traits, such as oil and protein contents, differ only slightly, except that amounts of hemicellulose and cellulose are higher. Seedlings are larger and young seedlings exhibit longer hypocotyls. Metabolic profiles of transgenic seeds indicate that, besides suppression of sinapine accumulation, other differences in primary and secondary metabolism are observed.
Subcellular Localization:
Secreted.
Sequence:
MASSLKKLITSFLLFFFYTIIVASSEPSCRRYKSIISFGDSIADTGNYLHLSDVNHPPQAAFLPYGETFFSVPTGRDSDGRLIIDFIAEFLGLPYVPPYFGSQNVSFEQGVNFAVYGATALDRAFFIEKGIVSDFTNVSLSVQLNTFKQILPTLCASSSRDCREMLGDSLILMGESGGNDYNYPFFEDKSINEIKELTPLIIKAISDAIVDLIDLGGKTFLVPGSFPVGCSAAYLTLFQTAKEKDYDPLTGCLPWLNDFGKHHDEQLKTEIRRLRKLYPHVNIMYADYYNSLYRLYQKPTKYGFKNRPLAACCGVGGQYNFTIGEECGYEGVGYCQNPSEYINWDGYHITEAAHQKMAHGILNGPYATPAFNWSCLDAASVDNESSFGS
The following text describes a protein:
Function:
Hydrolyzes acetyl esters in homogalacturonan regions of pectin. In type I primary cell wall, galacturonic acid residues of pectin can be acetylated at the O-2 and O-3 positions. Decreasing the degree of acetylation of pectin gels in vitro alters their physical properties.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MNLVDSKVGLTYFVDLGMNLADLEMRFVDLRMCFEDLGMDSKMGSVGLRTNFMDVRSLRYFLSFLDDGQRMGFCALSIGFPTILRLSSESEAAIGCSQQVPVHELACGLSGPYVPFCFQVCLDGSPPAYYFDPGFGDGVDNWIVQISCLYSQNIQQDIKTPLFIFMSAYDKIEIKYTFGDHMTPLVDAGKCSASQNQSLQEMRSEFLNALPKGDNPKLRGVFVDSVHHHNSLLKRWIPEIAIKVNGQLHTEAFADWYFDRKYTYLIDETNELPLENNARLIWAVDNATARVIYTATL
The following text describes a protein:
Function:
Involved in pre-mRNA splicing and cell cycle control. As a component of the NTC complex (or PRP19-associated complex), associates to the spliceosome to mediate conformational rearrangement or to stabilize the structure of the spliceosome after U4 snRNA dissociation, which leads to spliceosome maturation.
Miscellaneous:
MISCELLANEOUS: Present with 2170 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSAYIAMKGVITNVDENIRNDEDVAFEYEIQKTPQNILTWKRYIEYWKEEGRTDKQIRWLYERFCSQFVTDTSIWEDYIRWESTKEVVETSRIFWLFQRCLKSCVRDCDRICLSYLELAIEQYDLAMIRHALASSLMKMEREMHRKVWDPVIKFVEEKVLPLTQLDSTQEDEEESTDEAELINVLLVKGFTKGGFISEEISENGSRGDIWSSHILERYLKVAPQQKRNESLATLALTRDNITIKSVYEKYLPQDENSGKYLPSSELPFELNFNYLASLEKLGLDNQYEEFMRQMNGIYPDKWLFLILSLAKYYISRGRLDSCGDLLKKSLQQTLRYSDFDRIYNFYLLFEQECSQFILGKLKENDSKFFNQKDWTEKLQAHMATFESLINLYDIYLNDVALRQDSNLVETWMKRVSLQKSAAEKCNVYSEAILKIDPRKVGTPGSFGRLWCSYGDLYWRSNAISTARELWTQSLKVPYPYIEDLEEIYLNWADRELDKEGVERAFSILEDALHVPTNPEILLEKYKNGHRKIPAQTVLFNSLRIWSKYIDYLEAYCPKDANSSDKIFNKTKMAYNTVIDLRLITPAMAENFALFLQNHYEVMESFQVYEKTIPLFPPEIQYELWIEYLEVATSHQLSSLSPEHIRFLFEKALKNLCSNGIDCKTIFIAYSVFEERISGLISKSIEILRRGAVIGTVSVSTHLESRLQLWRMCISKAESTLGPSVTRELYQECIQILPNSKAVEFVIKFSDFESSIGETIRAREILAYGAKLLPPSRNTELWDSFEIFELKHGDKETYKDMLKMKKVLESNMLIDSASVSHEEGNINFVAAATSHAPNSHTLTQSTSSYSINPDEIELDI
The following text describes a protein:
Function:
Lytic polysaccharide monooxygenase (LPMO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding C4 oxidation products. Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate. Active on carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan. Also active on soluble cellohexaose, a property that is restricted to only a few characterized LPMOs.
Subcellular Localization:
Secreted.
Domain:
Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM). The genes for catalytic modules and CBMs seem to have evolved separately and have been linked by gene fusion.
Sequence:
MKFSSVLALAASAKLVASHATVFAVWINDEDQGLGNTADGYIRTPPNNSPVTDVTSTDLTCNVNGDQAAAKTLEVAAGDKITFEWHHNSRDSSDDIIADSHKGPVLVYMAPTEAGSAGKNWVKIYEDGYNDGTWAVDTLIANKGKHSVTVPDVPAGNYLFRPEIIALHEGNREGGAQLYMECVQFKVTSDGTTQLPEGVSLPGAYTATDEGILFDIYSSFDSYPIPGPAVWDGASSGSGSSGSGSSSSAAATSSAEKTATSTTAAATTTAVATSTSSATQVQPTSVATFTTSVRPTTSAAPTTSAPTSSAAPTGGTGTGSIQIYQQCGGMNYKGATGCASGLTCKQWNPYYHQCVQA
The following text describes a protein:
Function:
Involved in pre-rRNA processing and 40S ribosomal subunit assembly. Required for the early cleavage steps of 35S rRNA at the A(0), A(1), and A(2) sites (By similarity).
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MTEIGLSVDLATISKLLESAKSTLQEKQASDDDKHGQQKLLTKIPKIISSSFELPSYFEKKFVMGLKKDELVENSESYINDASFEPTVPIYESHVSAPGISKKKKNIKDTAGSNWFDMPATELTESVKRDIQLLKMRNALDPKRHYRRENTKSMPKYFQVGSIVEGPQDFYSSRIPTRERKETIVDELLHDSERRSYFKKKYLELQKSKMSGRKGQYKKLQQRRKPSYLK
The following text describes a protein:
Function:
Broad-specificity glycosaminoglycan lyase, which acts in an exolytic fashion degrading chondroitin sulfates and dermatan sulfate to yield only disaccharide products. Has a preference for chondroitin 4-sulfate over chondroitin 6-sulfate. Has extremely low activity against hyaluronic acid. Is not active against acharan sulfate, heparin or heparan sulfate.
Subcellular Localization:
Periplasm.
Sequence:
MLILSFLCPAFLNAQIVTDERMFSFEEPQLPACITGVQSQLGISGAHYKDGKHSLEWTFEPNGKLELRKDLKFEKKDPTGKDLYLSAFIVWIYNEQPQDAAIEFEFLKDGRKCASFPFGINFKGWRAAWVCYERDMQGTPEEGMNELRIVAPNAKGRLFIDHLITATKVDARQQTADLQVPFVNAGTTNHWLVLYKHSLLKPDIELTPVSDRQRQEMKLLEKRFRDMIYTKGKVTEKEAETIRKKYDLYQITYKDGQVSGVPIFMVRASEAYERMIPDWDKDMLTKMGIEMRAYFDLMKRIAVAYNNSEAGSPVREEMKRKFLAMYDHITDQGVAYGSCWGNIHHYGYSVRGLYPAYFLMKDVLREEGKLLEAERTLRWYAITNEVYPKPEGNGIDMDSFNTQTTGRIASILMMEDTPEKLQYLKSFSRWIDYGCRPAPGLAGSFKVDGGAFHHRNNYPAYAVGGLDGATNMIYLFSRTSLAVSELAHRTVKDVLLAMRFYCNKLNFPLSMSGRHPDGQGKLVPMHYAMMAIAGTPDGKGDFDKEMASAYLRLVSSDSSSAEQAPEYMPKVSNAQERKIAKRLVENGFRAESDPQGNLSLGYGCVSVQRRENWSAVARGHSRYLWAAEHYLGHNLYGRYLAHGSLQILTAPPGQTVTPATSGWQQEGFDWNRIPGVTSIHLPLDLLKANVLNVDTFSGMEEMLYSDEAFAGGLSQGKMNGNFGMKLHEHDKYNGTHRARKSYHFIDGMIVCLGSDIENTNTDYPTETTIFQLAVTDKAAHDYWKNNAGEGKVWMDHLGTGYYVPVPARFEKNFPQYSRMQDTGKETKGDWVSLIIDHGKAPKAGSYEYAILPGTDRKTMTAFAKKPAYSVLQQDRNAHILESPSDRITSYVLFETPQSLLPGGLLQRTDTSCLVMVRKESADKVLLTVAQPDLALYRGPSDEAFDKDGKRMERSIYSRPWIDNESGEIPVTVTLKGRWKVAETPFCKVVSEDKKQTVLRFLCKDGASYEVELEK
The following text describes a protein:
Function:
Negatively regulates Hedgehog (hh) protein signal in wing development. Regulates neural-specific glycosylation by binding to FucTA mRNA and facilitating its nuclear export in neural cells.
Subcellular Localization:
Nucleus.
Sequence:
MILENSDKLKDWLSVVLEPLCDADSSALARYVIALLKKDKSDKDLKRIMIEQLDVFLSEETTRFVERLFDAIASEEYLTVPAAPLITASSASTAELTVDQELALVIDGPQDDIEAVLVADSPPPPPKDNVIKPDSNQVKLEQASQDAREAEALAFISQEAGIAMHVPTDAKPAFDHKTKDSHNQQSASNYQHHHVRSASPPGRSSGVSGSGGGGPGGAGLAAGYADKENQPRDSRRRRASLRSRSRSRSRSNERAFRRSRSRDRRVNEREKTQRQFRNKSPPGSQTDNRHHGRRNFDRRRIGGNADDRPRFGNNKSRRSHSRSMSPERNARRNQNSPDRVQTAQANLIPAPVAPPAPVEHPASHPRQRCRDFDEKGYCVRGETCPWDHGVNPVVFEGINNTSLMMSMREYNPDAPEIWARSGGPPPGAGQGPVPPPTQPGQTTINPFSGNVRPTTLMSGSGPSPMGVPNPADYARNPGAPPQAAMMPFPFNPTAVTTPLQRQLIPIPVVDGAPTGGVAEVGKRRFELEDTVAIADVPTKRKVPINSRLGPRVNPNMQQHNSSLELRKVPRGLNTIAHLNNHFAKFGKIVNIQVSYEGDPEAAIVTFSTHAEANVAYRSTEAVLNNRFIKVFWHNDSSGADVGQMNQMGGGGGGGGRKNASQYHLHNVPAVPTPNADGAKISNANPLTEAGAGNIGTPATEQANTAAPASMRLKLNTTTAGGSAGGAAGAGAPGSGRPLNPAANAASIRKKQEEQQKAVHQLANGLRKRKQELLQSYMKQMKTALELVERMDQQDPQRAPTLQTIKVLQMTIDKLRKEIKADQDQLQAQMQQQQQQQQPPVKKTKEQQKKELLDMELELIAQQQEGNDTTAIQKRLEELQRNLGVGSAANNKSTHYAPASGAPGGGAGRKRPNLPEGPTRVDRRPKAIVVTGFAAEEADFVLGHFKNFGEISKHDVDREIPQLILSYATRLNAEQAVLRGKMYKDKRLQISWAPVVTPAPAPMAAPVEKSAAPGDMSVSLENPKQLIQSVSESESLLGSDTLPELRLEDEEEDEESEDRSWRR
The following text describes a protein:
Function:
May function as a G-protein-coupled receptor.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MVGLVLLWLTLSTGATVAKSEGRGLCSRSQVLFRDTCYEFVPLEHTFHGAQGWCERRGGHLVFIPGEDTQQFLQRHVTQDREWWIGLTGGSAHNGTTGGSGIWLDTSNVNYSNWQEGQAAPAPGACGYIGSGPSSQWAALEDCAQTFAFICEFGVGHSLACEGHNITMHCDSGEAILVQDAFYGRQTPYLCTRGVWPPPDLEGDCGWVSVKDEVAGQCQGLQACQVAADGTYFGDPCPTRGSYLWVQYRCLEGLRLVVPNGNFAFDNVTISLMWLLSPYTGNLSCVLSMGDGYTFDPYYPPSVSSNVTHQFTSPGEFTVFAECTTSEWHVTAQKQVILREKMETPRVTGCSGLSGSGAGLLCQAVFGEPLWVQVDLDGGVGATYAVLSGNRTLAEFTTRRGSQLYNLTLGRDIQELLGPGRHHLKIQDVSTSTASARSGNFTVHFVELLSGLRASWASDRVELGWDLLVNVSVAHGTLEELTFEVAGLNANFSQKEESGGRSSGSYRVAVPAEGTFLVTVHVRNAFSDLSLDIGNVTVTAPSGLREPSGMKAEAENGHKWDMKVFTEPELYVDPFTDVTLGWPDDDLSLDFHWSCGHCWAQWKTCVERQLLHTDQRLLVLHTFCLPPLNSAVTLHLAILRGQELERETERCLYVSAPLDLGPQISCQKNCRPVKADQDVLLTVTVGDETPVAMFNWYLDDTSPEKAEPLPAACRLRGFWPRSLTLLHSNSSVLLLNSSFLQTWGPVIHIRVTALTDHAYGEDTHVISMLPPPEVPACVIDPEEGSVLTSFAIFCSTPTAPGPVEYCFCVQSGSCLHCGPEPALPAVYLPRGEEKDGFVLTVVISVTDQAGDREQTHMAVKVGHDDTGVEDVTFQETVSDRITTALYHEHGHEELLLLAKAVSSELNKEDQGPGSGRLRMDIKRKVRELVLRSLSTVTTGLENMQRVQALAEALREVTHHSEELTLVAQWEASQALQRNTEALLAAKVHPKDQRRQEATRAMFEAVGSVLKASLSHGSDEPAEANSSQVAHIVAQLLQVVDRLQSALLLGTLPGGLPAILATSSVSVYTDRIQPRSWQGSSVHTTAADSVIFILPATTFLCPTEDSQEPVDIRMMSFSQNPFPSRSHFEVSGTVGGLRLTSSSGRPIPVKNLSQNIEILLPRISTRIKPNTLSLATGDALSVNVTAGDAALGIQLHWGPGVALTLSLGYGYHPNETSYDAQTRLPAVADAGDLPTWILYPEDLPFGEGIYYLRVVPKDDLESTSDRNLTVGITTFLAHCVFWDEAQGTWDNSGCRVGPRTTTSQTHCLCNHLTFFGSTFLVMPNAIDVHQTAELFATFEDNPVVVTTVGCLCMVYVLVVIWARRKDIQDQAKAKVIVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTLTLYGSDGESEPHHLSDSDAAVFERGGVDVFLLSTLFPLGELQSLRLWHDNSGDRPSWYVSRVLVYDPVVDQKWYFLCNSWLSIDVGDCVLDKVFPVATEQDRKQFSHLFFTKTSTGFQDGHIWYSVFCNSTRSSFTRVQRVSCCFSMLLCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSVLMFPINLLIVQIFRNTRPRLLMEKNGKRKQGSPHPTPLPQPTEEGLLTPETGIQSLISSLFKALKVPPPASGWDSTNQMDINSLLALMEDIVSPESTAGQEFWEEARGREDPLTFTHGSVKPEENTWHLGPRLAVSDLWKDSIYRPCLYIRLEHVERKLRLVGPQGFRHPHSHAQALRQLHVLKGHLWGQPGTPALAYTSTPRASKCPGCLPWWCVLVGWLLVATTSGVAAFFTMLYGLHYGRASSLKWLISMAVSFVESVFITQPLKVLGFAVFFALVLKREDDEETLPLLPGRLSSPGPHVLSQSRRRSSKDAYRPPPAAAIEKMKTARLKEQKAFALIREILAYLGFLWMLLLVAYGQRDPSAYHFNRHLERSFTQGFSAVLDFRGFLEWANTTLVKNLYGHHPGFVTDGNSKLVGSAHLRQVRVRESSCAVAWQLRGSFDGCRAPYSLDAEDLADYGEGWNASAHNSSDGFPKVWQYQSQSRRRGYPTWGKLAVYGGGGYVVPLGTDHQSASRILQHLFDNRWLDALTRALFVEFTVYNANVNLLCCVTLTLETSGLGTFFSHVTLQSLRLYPFTDGWHPFVVVAELVYFLFLFYYMVEQGKLMRKQKWGYFCSKWNLLELAIILASWSALVVFVKRAVLADRDLQHYRKNRGEGVSFSETAAADAALGYIIAFLVLLSTVKLWHLLRLNPKMNMITSALRSAWGDISGFVTVILIMLLAYSIASHLIFGWKLRSYKTLFDAAETMISLQLGIFNYEEVLDYSPVLGSLLIGSCIVFMTFVVLNLFISVILVAFSEEQKSDQLSEEGEIADLLLMKILSFLGIRCKREETWSSSEQPELSPNTLSLQPAQALPGI
The following text describes a protein:
Function:
Participates in the formation of new permeability pathways in Plasmodium-infected erythrocytes enabling the uptake of nutrients from the blood plasma. Required for maintaining invasion capacity of merozoites. Required for the trophozoite to schizont developmental transition of the intracellular parasite.
Subcellular Localization:
Host cell membrane; Single-pass membrane protein. Host cell membrane; Peripheral membrane protein. Parasitophorous vacuole membrane; Peripheral membrane protein. Cytoplasm. Cytoplasmic vesicle, secretory vesicle, rhoptry. Note=Export to host cytosol is mediated by the Plasmodium translocon of exported proteins (PTEX) complex.
Sequence:
MRSKHLVTLFIITFLSFSTVKVWGKDVFAGFVTKKLKTLLDCNFALYYNFKGNGPDAGSFLDFVDEPEQFYWFVEHFLSVKFRVPKHLKDKNIHNFTPCLNRSWVSEFLKEYEEPFVNPVMKFLDKEQRLFFTYNFGDVEPQGKYTYFPVKEFHKYCILPPLIKTNIKDGESGEFLKYQLNKEEYKVFLSSVGSQMTAIKNLYSTVEDEQRKQLLKVIIENESTNDISVQCPTYNIKLHYTKECANSNNILKCIDEFLRKTCEKKTESKHPSADLCEHLQFLFESLKNPYLDNFKKFMTNSDFTLIKPQSVWNVPIFDIYKPKNYLDSVQNLDTECFKKLNSKNLIFLSFHDDIPNNPYYNVELQEIVKLSTYTYSIFDKLYNFFFVFKKSGAPISPVSVKELSHNITDFSFKEDNSEIQCQNVRKSLDLEVDVETMKGIAAEKLCKIIEKFILTKDDASKPEKSDIHRGFRILCILISTHVEAYNIVRQLLNMESMISLTRYTSLYIHKFFKSVTLLKGNFLYKNNKAIRYSRACSKASLHVPSVLYRRNIYIPETFLSLYLGLSNLVSSNPSSPFFEYAIIEFLVTYYNKGSEKFVLYFISIISVLYINEYYYEQLSCFYPKEFELIKSRMIHPNIVDRILKGIDNLMKSTRYDKMRTMYLDFESSDIFSREKVFTALYNFDSFIKTNEQLKKKNLEEISEIPVQLETSNDGIGYRKQDVLYETDKPQTMDEASYEETVDEDAHHVNEKQHSAHFLDAIAEKDILEEKTKDQDLEIELYKYMGPLKEQSKSTSAASTSDEISGSEGPSTESTSTGNQGEDKTTDNTYKEMEELEEAEGTSNLKKGLEFYKSSLKLDQLDKEKPKKKKSKRKKKRDSSSDRILLEESKTFTSENEL
The following text describes a protein:
Function:
Plays an important role in fat metabolism. It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activity against insoluble emulsified substrates than against soluble ones.
Subcellular Localization:
Secreted.
Sequence:
MLMLWTFAVLLGAVAGREVCFDKLGCFSDDAPWSGTLDRPLKALPWSPAQINTRFLLYTNENPDNYQLITSDASNIRNSNFRTNRKTRIIIHGFIDKGEENWLSDMCKNMFRVESVNCICVDWKGGSRTTYTQATQNVRVVGAEVALLVNVLQSDLGYSLNNVHLIGHSLGSHIAGEAGKRTFGAIGRITGLDPAEPYFQGTPEEVRLDPTDAQFVDAIHTDAGPIIPNLGFGMSQTVGHLDFFPNGGIEMPGCQKNILSQIVDIDGIWEGTRNFAACNHLRSYKFYTDSIVNPTGFAGFSCSSYSLFTANKCFPCGSGGCPQMGHYADRYPGKTSRLYQTFYLNTGDKSNFARWRYQVTVTLSGQKVTGHILVSLFGNGGNSKQYEVFKGSLQPGTSHVNEFDSDVDVGDLQKVKFIWYNNVINPTLPKVGASRITVERNDGRVFNFCSQETVREDVLLTLSPC