The following text describes a protein:
Function:
Catalytic subunit of the DNA polymerase zeta complex, an error-prone polymerase specialized in translesion DNA synthesis (TLS). Lacks an intrinsic 3'-5' exonuclease activity and thus has no proofreading function.
Subcellular Localization:
Nucleus.
Sequence:
MFSVRVVTADYYLSSPIPGLDPCQSRFREAPAKKVPVVRVFGATPSGQKTCLHLHGIFPYLYVPYDGFGQLPENYLRHFAFSIDRALNIALGNPSSSVQHVFKVSLVHGMPFYGYHEKERQFMKVYLYNPAMVKRVCDLLQGGAVMNKIYQPHEAHIPYLLQLFIDYNLYGMNLINLAAVKFRRAKKKGNTFEEIGCSKDNLSGHFVTRTLHRWEDNQIPSSLILEGIERQSTCELEVDAVAADILNRLDIEAQIGQNPGLQAIWEDEKQRRRDNKESSQISPPNSQDRGCVTTTDSEKIFQKRLKEILKQSDLSVTLSGSVDYSNGLQEFSAELTLHSELHSPAVVSCSPANMVEAHRDTGINKEESYSKYEEENALINEEAILNIMENSQHFQPPSQKFNNTPGLMDNSVDQAMVHLLAGLEDDGYEIGRPSTLSHFSSGSCQNPQNSDDEENEPQIEKEELELSLLMSQRWDNSPNDVSGKRRSVSRSKNQSSSEYDSSSEDDMDWNDNNLLLGNLSIPQLDGTADENSDNRLNNEGSRTHTSVIATSKTSVQTSIFHKDAATLESPSSAKITFQCKHTSALSSHILNSEDLEGLSQPNMMDIRPEMAVHSIAKEGTYSVKYPTPFNNILNSENSVKENNKSEILPVLCEDISSVSRHLSNRKYTGIRKITNDVPLHMSHQIGESVMVKNSNFTDPVHSKITPSETNKNTSGTHINSLFSEPENCESLSCFEDPSTVIHSSENTTGGDSLNNLKIRYEEFHEYKAQKTNMNQQAPHYMFFPSVVLSNCLSQPQRLGPVTYKLQQGRKQSRLKLTKKKVLLSSQQPTNVCDNPFTEESCYIQGNASNNIPDKDSSLPNDNEVQVPHGAFENKMSMGTSNCVDCHFEDGAQESYQAFGLCGNKYTLRAKRKINYETEDSESSFGAHHSKINLPHSVGNDECLDGSKKCQKRRKLAKKLPPVIIKYIIINRFRGRKNMLVKLGKIDSSEEQVILTEEKMNLYKKLAPLKEFWPKVPDSPATKYPVYPLTPKKGQKRKAKCKSTKKKIGKLHNINSKNIKRSLYFRRRPHAFLSPPLPSYNTEAEDCDLNYSDVMSKLGFLSERSASPVSVSPPRCWSPTDPNAEEIMANLKKETLVFQNANMYSSKIISPYMGKKCQSKIQTKRCKKQLVASIVRTNKKNKGKLINKPGSEVKKKPRAKQKQKEKHSKIETVTDEKNAVPSSEVKHLNVPDGAHSLGNPQSLYIQKEIPSAGYSAGHVPSVQLALTANSQINPLIYFHSLLENEKPLGQQGSTLTKEDLHSSITSVVSGKEKAKINFQRSNNQSGIFRTKESSLIQNSAFDQSHHISQVTLNTYGSKDIMPKKAEVVPNLQNRFLSSFGKMNDNYIPSDTVKMDQVHPGNFLHCKDNQQSVVHLSEATKHSDHISFFKTSEEGHDSFQLPKTCFVASLRSPVKKIEWEQKQRGFVLDMAHFSSEKNRKQKGLSETNSQAKSDSHCKGKTLLTPSAFSEGHSGLAVLKELLQKRQQRVQANSMHKQLPAKTHLSRSVSYPPDKIKSMKKSRSVARKPRPRDKKSKEKTFKFLKDSANQLNNKTGPVTPVSSPVFYSDPGFESCYSLEDSLSPDHNYNFDINTIGQTGFCSLYSVNQFVPADQNLPQKFLSDAAQDLFPGQAAESELLGHNNKPAKEENHYSSDPSMWLRSGPLSPQLFDKRCLDNNDNHLHSQWKNKIFPSPFQPNLPLDIQQAEMCQKDRNAVKKGIFLNLSSPTDEWDQSHFKKETTSDPSHSLDSASVSFSSILSSPDGELMDAASEDLELYISRNNERLTPTPDSSPRSTNSPSQSKNGSSPPRAARILKPLMSPPSREEIMSTLLYHNLSEAIYQEPFCSNPTDAPEKPREIGGRLLTVETRLPNDLLEFEGEFSLEGLRLWKTAFLAMAQSPKPGSPLRNSQCTTDKKPKNSHGTSEDKKIVIMPCKCAPSYQQVKLWLQAKEDNEQLRRRTFMKSTEIEKADECLNCVSLPKNIYQIAMAGEDSSKPVVQLEDLCSSSTTPTPPQTEQDKNLVQKKEMPLVTTAVEMDREEEDSVNYSPPDSPMIPPWQQVASPDSKQFNSEDSEGIISLEETELLPEKEKKYIKNESKKPFSVSPLVNKEYDGNSENIYLHSTPIRKIQSQGRIPEGLEGSSSLPGPSTQKLNCRRGNNANALRKVLLTTQVKNQFTAQTTPKKETSQIEGPSLNNSYGFKISMQNLQEAKSLHEVQHLTLLSLELHARTRRDLEADPEFDPICALFYYISSDTSLPNADKTEITGAIVIDKEKTRTISIQGNREHAPLLTRSGISGLEVTYTTDERALFQEIVNIVKRYDPDILLGYEVQMHSWGYLLQRAAALDVDLCQMISRIPDDKKENRFAADQDEYGSDTMSEINIVGRVVLNIWRIMRHEVALTNYTFENVGFHILHQRFPLFTPRVLSDWFDNKADIYRWKMVDYYTSRVHGNIQLLEQLDLIGRTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKPMNYIAVTPSIQQRAQQKAPQCIPLIMEPESRFYSNAVLVLDFQSLYPSIVIAYNYCFSTCLGHIENLGKYDEFKFGCTSLRVPPDLLYQLRHDITVSPSGIAFVKPTVRKGVLPKMLEEILKTRIMVKQSMKSYKHDKGISRMLDARQLGLKLIANVTFGYTSANFSGRMPCIEVGDSIVHKARETLEQAIKLVNDTKKWGARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNPKPVKLKFEKVYLPCILQTKKRYVGYMYETVDQKDPVFDAKGIETVRRDSCPAVSKILERSIKLLFETRDISHIKQYVQNQCMKLLEGKASMQDFIFAKEYRGLSAYRPGACVPALEITRKMLAYDRRSEPRVGERVPYVIVYGMPGLPLIQLVRRPIEVLQDPNLRLNATYYITKQILPPLARILSLIGIDVFCWYHELPKIQKAGRTAHVEQESRKGTISQYFTTLHCPVCDELTQHGICSKCRSQPQRAVVILNQEIRELERKHDCLVKICKNCTSCLDRQIPCVSLNCPVLFKVSRVSRELSKAPYLRQLLDQF