The following text describes a protein:
Function:
Force generating protein of eukaryotic cilia and flagella. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.
Subcellular Localization:
Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MAEDEGMTAAAPSSSVKDIRFDYIRDRVCSCLKVPDSAYDKLVSGDGRTSLVQFMEEAHTKRLLIMLDGKDLSATVKPPPKFKKKTVYFLKLQETKLDNDNIKKLVIHGEISENPLETLAAISQDVFMPVLTAPANQQGWPDVVAKEVTENLHKFVSNVFVTIGQMKGQTLLPLPPQNTVPTLQPEQSMHSLKDQDKIHILESAIVTWTKQIKNVLKADPDAPLKEPGAYPGPLTELNFWSERAANLNSIHEQLTSEKTQKVVKVLELAKSTYYPAFQRLFREVEAAQQEANDNVKFLKPLRKYLDKLNMMDDFPMLVDLFKPIMHTLMLIWKHSKSYNSSTRFVTLMQEICNDLIMQACKYVPGSDLIQMEPSEAVDKLRMTLRVLGTFKNYYFEYRALSMQDTPENPWKFQNNSLFARLDSFLERCHDMMDLMSTCMQFNRLERVEIGGTKGKVLTNGVKAIHQDFTSAVEKFQQVTYDVMDVDAKQFDEDFFGFRVVIKELERRLAAIIIQAFDDCTTIGTTFKLLDSFEGLLDREVIAHDLEKKHTDLLHSYARDLKDVADLFHQYKDRPIVAKNSAPYSGAAYWVRGLMERIKDPMDRLLTMNKMVLESELFREIQRTYDHLWEEMTEYRTRAVDAWCAQVAATSDEKLNLPLLSLIEETADGIRVLGVNFDPALVRLLRETKYFLLLETSTQDKNADRNAEKAAEGGEVEVVKKAPKLSVPDSAKDLFASADTFRQQISALDLICSIYNKVQRTILAVEKPLVQQKLDAVEQALNRGLAELNWKCAEIDTYIKECMELVKDVDLVLNTIKDNVKATQGILAMWEKNLMFERKDGKTYTFDELNDAFNQLIQQRHSEIRDAGKEITKLLSSSNRVLKVSKGAASWRAYVDYFSNIVIDGFSAAIISTVRYLLSQIDPDILAKTESSPLLEIQVELVAPDIVWKPDLGEGGAKPGLRDMIKKWLQSFLEIGQLMKRLDVGEGNYAKELEEDFEVYDALNQVMMVTLANESRCEDFKNQFAKFDYLWKQDLQATLQQFITDNGVTLPDGTRDDPPLAKFEEQIVKYKNVASEIASFKDTMTMGYVKVNAKPLRQALSTWASKWVYLFTHYLQEKVVNSITELYTFMDTSNSTLDLKVMGEGVEEEPEYHPDQDPEEAAAKKAAEEEEKRKALYAIMACMRDIRRRTERGTDTMFEPLKETVTALHTFGIQLSDTVLHQLDNAEFNWRTLKKKMLNRREQLAPLQQAEAVEIRRKSDAFNERVEDFRTFFQRKAPFAVSGGELKLEQVKPAYKLLDEFRSGSLEGYPSVLGIIAESKQLQEAQDLFELYQPGYLQLQRCSEELGHLKSLWDTVGTVMFTFRDWYKTPWDKIDVDFLVEETKKLSKDIKMLNKAVRNYDVYRMLEEAIKAVLTSLPLVQDLHHPAMRERHWKLLMQTTGKHFVMDDKFCLGDLLALELHNYVDACSEIVDRAQKELNIEKQLKKIEDTWAGLSLAFSTYQDSDVMALLVDDAVNEALEADNLQLQNLSGQKYVQSNPMFLETVSKWQNNMGRVSAVLETWQNVQKKWQNLESIFIGSADIRVQLPEDSKRFDAVNADFQELMRTAPDITNVVEACTLDGRQERLENMQSMLEQCEKALQEYLETKRVAFPRFYFVSPADLLDILSKGSNPQLILRHLQKCFDNIDNLSFRKDERGDPTKIATHMHSKEGEVVEFVEDCSCDGPVEVWLQNVVDSMKLALQVEFRKAIPTYDELPRTKWIYVYSAQNTVVVSRTFFTQEINEAFDDLEEGNEEALKVELDRQVQQLADLIDEINKEQTSLDRKKLITLCTIDVHSRDLVQKLIDERVEDQMCFQWQSQLRYIQSEKTKTCQVNICDAEIAYSYEYIGNCGCLCITPLTDRCFITLTQAQRLVLGGAPAGPAGTGKTETTKDLARALGIQCYVFNCSDQMDYKAMGHTYKGLAQTGAWGCFDEFNRIPVAVLSVCSTQYKTVLDAIRAKKERFTFEDADISLKSTVMAFITMNPGYPGRAELPESLKALFRPVSMVVPDLALICEIMLMAEGFQMSKILSRKFVILYKLCEDLLSKSRHYDWKLRAIKTTLYVAGGMKRAAPELSEDKVLLRALRDFNLGKLTADDTSIFMGLLNDLFPKTLELVPRALDKAFDEAAHKAATELGYQPDDQFLLKISQLRELFVVRWSVFLLGAAGCGKTAVWRTLLRAQNSSGEKTIYQAVNPKAVTRNELYGYLHPATREWKEGLMSVTFRNMANNKTNKHQWIVLDGDIDAEWIESMNTVMDDNKMLTLASNERIPLTPSMRLLLEINHMVHCSPATVSRGGVIFINADDVGWQPVVASWIDKLEAAEYRPLLTALFTKYVDPCLEHCRRNFKTVVPLPAVNQAMTICKILEGILPKETVRGAPPPDKKLLHYHFVFACVWAFGGCMLVDKVTDYRTQFSKWWVSEWKDVQFPEKGLVYDYYVDEQNCIMVPWEDRVTKFQYIPGDFTSLFVPTVETTRLTYFLDSLVSNKHYAMFVGNTGTGKSAIMVNKLRNMDTETMSFYTINMNSLSEAPALQVILEQPLEKKSGVRYGPPGSRRMVYFVDDMNMPLVDKYDTQSSIELLRQMVDYHGWYDKVKIQLKEIINCQMAACMNPTAGSFNITPRMQRHFVTFAVQMPNAEITRAMYYQIIDGHFSSFDVDVAKMSNKLVDATCELHRNVMHNFLPSAVKFHYQFNLRDLSNITQGLTRAIKEYYREPVKVARLWVHECERVFRDRMINEADMAKFDEFRVAVTKKFFDDCGGMVAIEERPLIYASHASMTYTPEDVPVYNALSSYDVLRKTLEDKLREYNESNAVMDLVLFQQAMEHVTRIARIIDLPRGNAMLVGVGGSGKQSLARLASYICGYEVYQISVSSTYGINDFKENLLGLYRKAGTKGTPITFLMTDNQIVKEGFLVYINDLLSTGYIADLFTPEDKEAFTNAVRNEVKAAGILDSAENCWDFFIDKVRKFLHIVLCFSPVGDKFRIRARQFPALVNCTMFDWFHGWPGEALVSVAQRFLVDVPNMEEVVRENIAYHMAYAHQCVSEASERFKEAFRRYNYTTPKSYLELISLYKMLLQLKRDDLRRSKERLENGIDKIAQAAAQVTDLQRVLKEEQIVVDEKKAQTDELIVSIGKEKAIVDQAVEAGREDEEAATALQTEVSAFQAECERDLLEAEPIIAQAEAALNSLNKKELSELKSFGSPAAEIVQVAAACLVLTCGGKIPKDRDWNAGKKMMADVNSFLSSLMNFDKDNVPVVCVEVVEKDYISNPGFTPDNIKGKSAACAGLCSWVINICKYFRIYQVVAPKRAALAEANKKLDTANKKLKVIRDEVKRLQDRVALLEQSLMKATEDKNAAIAQADRTARKAQMAERLINGLSGENTRWGAEIKRLESLEGRLVGDVLIASAFVSYAGPFNMQFRKSLVDEKWLPDIIERQIPMTQGIRPLDLLTDDATKAKWANEGLPTDPLSVENGAIMSNASRWALMIDPQLQGIKWIINKETNNGLVIIQQSQPKYIDQVINCIENGWPLLIENLPVDIDAVLDPVIGKMTIKKGRNIIMKIGDAEVQYDSRFRLYLQTKLSNPHFKPEVAAQTTLVNFCVTEKGLEDQLLALVVDHERPDLQEQAAGLVRSLNEYNITLVELENNLLFNLANATGNILENIELIEGLEETKRTAVEIEEKVKLAKQTEIQIAKAREVYRPVATRGSLTYFLIDNLNALDRVYHYSMANFVFVLKKGMDMTPGGKDESKVPLAERLNQEVDLDKRVELLVETTCFVLIGYVAQGLFERHKLIVATQLCMQILRSRGELHYAKFEYLLRGPKVMGADNPLHDWVSDSVWGSVQALKELDDYQGLPEDLIGSSKRWREWMELERPEDEPLPGDWKRMQEFDKLLLFRALRPDRLTSAMGRFVTNMLGAKYVTSQPYDLERSYQDASPGTPIFVFLSPGVDVAGSVEALGKKLGFTLDNGKYASVSLGQGQEPIAMDRLSAAHKNGGWVLLQNIHLTIDWTTNQLDKKVDKLVEGAHPDFRLFLSAEPPPSLERGLPISLLQNSIKLTNEPPEGLKANLRRAWNNFNEEILESCAKQAEFRAIVFALCYFHAALLERKKFGVGNLPGARSGIGWNMNYPFNTGDLLCCGQTANNYLENNVKVPWEDLRYNFGEIMYGGHIVEDYDRRLAMCYLRKYVNEGLLDNMEFFPGFAMPPNTANHRQVLEFIDEVMPPETPLAFGLHPNAEIGFKLREAESFCNSLVQLQPRESSGEGGMSAEERAKLVLDEVVDKLPDIFDMEDVRSKINPDDPNMPFVMVAIQESERMNMLLAEMKRSLLELDLGLKGDLTMTEPMERLLKALATDAVPGSWRNLAYPSLRPLGSWLGNLLARHAQLVDWTAELSTPKAVWLSGLFNPQSFLTAVMQATARRNDWPLDKTVIITEVTKKQPDQIEANSRDGAFIHGLTLEGARWDDKIGALDDSKPKELFCPMPVILVRAVTQDKAEMKDVYKCPVYTTEARFREEVFEAQLKSKHTEIKWVLAGVCLFLDVV