lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Domain:
Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
Sequence:
MAMAKGLWSSTVLLLLLVSAVLMPTFVIPVSSSEDPEPQTSEETIDEPVKESFTEDKYIGAAPGVVAAVYFPKNLNNVVKAGEPTQVLINITNDGAGPMQVQYVRASLHLPHDHRVIIQNFTVQEYSSSIPQGNKATFSYWFGVVKFLQPGNYDFVGKFIYELDNKAYTHVFFNSTIDIVESGGFVSGETIFLSTLGLGLLGYLGMWVYSKVQDLIKKQKRSSKKVETGTRTNSDAHASEWLQGTSFTQKLSKNISQQRKSFKKKSSSKDSKDASKDS
The following text describes a protein:
Function:
Acts as a magnesium transporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MPPVTEPQDECAANGVGNNSLESQQELDINRNARMVLESKESTVVLVGSRANTKGVQEEDSLLENGSQSTESDDPNADACPEVSIPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWEVFTEVTEVFILVPALLGLKGNLEMTLASRLSTAVNIGQMETSKEKWAMITGNIALIQVQATVVGFLASMAAVIFGWILDGHFLMDHAVLLCASSVSTAFIASMVLGEKKSFPSSCKHIKRMTGQGLVMIGVIIGSKKLGINPDNVATPIAASLGDLVTLALLSGISCGLYKEIKNNVYVNPVVCILFLALLPIWFVIARRNPATREVLSSGWEPVIIAMAISSVGGLILDKTVSNPNFAGMAVFTPVINGVGGNLVAVQASRISTYLHMTGPPGEETELIPRKCPSPCRTFFSSDMNSRSARVLFLFVVPGHLIFLYTISSMQGGHTTLTLIFMVFYMMAALLQVLVLLYIADWMVHWMWGRGMDPDNFSIPYLTALGDLLGTGLLALSFHILWLIGDRDTDVGD
The following text describes a protein:
Function:
Non-catalytic component of the proteasome.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MNHLPQAWGRPRDDIYGAYDASYLQQNGPNQHTQSPIVTGTSVVALKFKDGVVIAADNLASYGSLARFTDVKRLRKFADTSVVGFGGDVSDMQYLDRLLQSLDTEEAYSASGHTLNARNLHKYLSKVLYKRRSDFNPLWNTLLVAGLDEHDKPFLASADLLGTTFSSPSLATGFGAHLAQPLLRKVAPDEEATAKLTKEAALEAIKESMKVLFYRDARSMDKYSIAVITKEGIDLKENEQLEKQSWAFAEQIRGYGTQVN
The following text describes a protein:
Function:
Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.
Sequence:
MTGLRYDRQVRLWGDEGQSAIGSTSVCVLGASALGTEILKSLVLAGIDSFCIIDDAVVTQPDLGTNFFLEAADLGKSRAEAALRLLKELNSSVRGTCSTRSPTSTTDAHLEELTTFSVVVATNMAESAASPISAFLYERGIPLVYSRVFGFLGTLRVAVAEHPIVNTHVENAPPDLRLDAPFPSLQALIDAVDMDKMTDEQVRHTPYLILYALALKEYRKSLGDPTAFPATHAQRKALLPHVMAFARERESGGTDENFDQAKASLARSLLKTQIPAGVRAVLADAKCAEGEAAAAARGGDPFWIVCTAMRRFVDRHGVLPLAGKLPDMASDSASYARLAAVYHERAMADADEVLAEARALEKQTTASATDAVQEHDENDDGSGESSKRLKASPPSPTTTSASDSSAGDGTTPSSISHETCMRLCKNAASIALQRGTRVDSWKGEGFRSVLATIAATAQLDEETGAPLPVDANAGAAHAAVWLLLQRAADRFAEEKSRFPGTNGIPCEMDARDLWERVKRIVDEGLARREVENGDESMEEDDLTAEAVLAQVPYSACSEMCRYAAAEPHAVASLLGGIAAQEVIKLATRQYIPVENTLVYDAHSGLTETFKLYVPAVAPGRSRISGTVVKPDPPRAADAVVVPAQPPPRIRPEPGSRIFRQSTLSNGMRVATEAFRVKQGDRAVITVIVGAGSRHETESLNGIAHYTEHMILRGATPAMQLKSFEYAHDDRLGGSTTTERTEFHMYSEMCRYAAAEPHAVASLLGGIAAQEVIKLATRQYIPVENTLVYDAHSGLTETFKLYNLCTIVVDKFNELFVSIKLSMNPQTFPNRRVPSRFAGGEGTPGTFGNLKGFHKQPASTLALLACVLVQCRRTRATSKGNETVVKPDPPRAADAVVVPAQPPPRIRPEPGSRIFRQSTLSNGMRVATEAFRVKQGDRAVITVIVGAGSRHETESLNGIAHYTEHMILRGATPAMQLKSFEYAHDDRLGGSTTTERTEFHMYCREAEDAEPAIALLARMIVDAHFQDENVERERRIIQAQCMQSGCDIRVFALECLHKVAYHPNPLGLFTGGQLRTNEAITALDICRFYDAHYKSTNTIITAVGDVDHEEIVRWAEYHFKRLCLTSETDSFFVELAVQGPSDFWNSEDGLILQLFNYAILCKAAPIFSRHNRHVNDVMSLLPYKEFTSVSQCFFTHLGLHVIIARWRYFAYGFTAADLEQTKEHYKIYNQEKGQCVRAVSCMLNLHMFHTGRHDSPDKMWSRVQAITIDRFRAVAKRILLDGEFTLVGYVPSDHPHPRLRTRKSIEFHLRRAPITRRVTRGDDSRSEMTLTE
The following text describes a protein:
Function:
Cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling. Regulates glutamatergic and GABAergic synapse development. Promotes the development of inhibitory synapses in a PLXNB1-dependent manner and promotes the development of excitatory synapses in a PLXNB2-dependent manner. Plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity. Promotes phosphorylation of TIMD2. Inhibits angiogenesis. Promotes axon growth cone collapse. Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MTMALPSLGQDPWSLLSVFFFQLFLLLSLPPASGTGGQGPVPRVKYHAGDGHRALSFFQQKGLRDFDTLLLSGDGNTLYVGAREAILALNIENPGIPRLRNMIPWPASEKKKNECAFKKKSNETQCFNFIRVLVSYNATHLYACGTFAFSPACTFIELQDSFLLPILKDKVTDGKGQSPFDPAHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDIFLRWLHPDASFVAAIPSTQVVYFFFEETASEFDFFEELYTSRVAQVCKNDVGGEKLLQKKWTTFLKAQLLCAQPGQLPFNIIRHAVLLPADSPSVPRIYAVFTSQWQVGGTRSSAVCAFSLTDIERVFKGKYKELNKETSRWTTYRGSEVNPRPGSCSMGPSSDKALTFMKDHFLMDEHVVGAPLLVKSGVEYTQLAVETAQGLDGSSHVVLYLGTSTGSLHKAVVPQNSSAYLVEEIQLSPNSEPVQNLQLAPTQGAVFAGFSEGIWRVPRANCSVYKSCVDCVLARDPHCAWDPESRLCSLLSGSPLTWKQDMERGNPEWACARGPMARSPRRQSSPQLIKEVLTVPNSILELPCPQLSALASYHWSHGKAKIPEASSTVYNGSLLLLPQDGVGGLYQCVATENGYSYPVVSYWVDSQDQPLALDPELAGVPRERVQVPLTRVGGGASMAAQRSYWPHFLIVTVLLAIVLLGVLTLLLASPLGVLRARGKVQGCGMLPPREKAPLSREQHLQPSKDHRTSASDVDADNNHLGAEVA
The following text describes a protein:
Function:
Involved in transcription regulation induced by nuclear receptors, including in T3 thyroid hormone and all-trans retinoic acid pathways. Might promote the nuclear localization of the receptors (By similarity). Likely involved in the processes that promote cell division prior to the formation of differentiated tissues.
Subcellular Localization:
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Nucleus during interphase. Weakly concentrated at centrosomes during mitosis and colocalizes with AURKC at the midbody during cytokinesis.
Sequence:
MAFSPWQILSPVQWAKWTWSAVRGSGAGEDEAGGPEGDPEEEEDSQAETKSLSFSSDSEGNFETPEAETPIRSPLKESCDSSPGLAEPEAKPQESREADEQLVAEVIEKCSPDTCSRSSENEAPQATVDSHPVKDVRGKAEHDVSKISVVRPFSIETRNCTDDPAALGTAAAHGCVPVLPGMALPSTTPEATQDEPVMDRGMGVTLEAFTEASLKTGGPCPEPVASRSKLRKPKPVSLRKKMAPEPEMLMEGSPLPKASSPWLPDGLDQNANPSVLRGSGAQRSPLNLKETAGVLSNDTSDSGVEVAPGSPPLQLEDDFTEDGENVKIRSALPKQSGRKPSNKLAPSIRKDGVSKPVGVEQPSDPTVQDALLDQMSPKLDPSKRSHPPANFFGSGPILQNSPPLSSKCSHHFDPNNINTDDSGDPCKPTPALTSSGFCPATGNHVNEILDSPKKAKSRLITSGCKVKKYEAQPLDLDACSQDEGAVISKISEIPNRDGHATDEEKLASTSSCAQKSAGAGVKGIEKETCQKMEKEELAVHGLLESSSEKAPVSVACGGESPLDGICLSEADKTAVLTLIREEIITKEIEANEWKKKYEETREEVLEMRKIVAEYEKTIAQMIEDEQRTSMSSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKVHAEEKLDRANEEIAQVRSKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD
The following text describes a protein:
Function:
Translation factor required for the incorporation of the rare amino acid selenocysteine encoded by UGA codons. Replaces the eRF1-eRF3-GTP ternary complex for the insertion of selenocysteine directed by the UGA codon. Insertion of selenocysteine at UGA codons is mediated by SECISBP2 and EEFSEC: SECISBP2 (1) specifically binds the SECIS sequence once the 80S ribosome encounters an in-frame UGA codon and (2) contacts the RPS27A/eS31 of the 40S ribosome before ribosome stalling. (3) GTP-bound EEFSEC then delivers selenocysteinyl-tRNA(Sec) to the 80S ribosome and adopts a preaccommodated state conformation. (4) After GTP hydrolysis, EEFSEC dissociates from the assembly, selenocysteinyl-tRNA(Sec) accommodates, and peptide bond synthesis and selenoprotein elongation occur.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAGRRVNVNVGVLGHIDSGKTALARALSTTASTAAFDKQPQSRERGITLDLGFSCFSVPLPERLRPAPPGTEPESGAELQITLVDCPGHASLIRTIIGGAQIIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKTDLLPEGKRQAAIEKMTRKMQKTLENTKFRGAPIIPVAARPGGPEAPETEAPQGIPELIELLTSQISIPARDPSGPFLMSVDHCFSIKGQGTVMTGTVLSGSVSLGDSVEIPALKVVRKVKSMQMFHTPVTSAVQGDRLGICVTQFDPKLLERGLVCAPESLHTVHAAVISVEKIPYFRGPLQTKAKFHITVGHETVMGRVMFFSPAPDSFDHKPVLDSFDFSQEYLFQEQYLCPSSAPAATDTTDSGGDDKKAGQASEGHCPRQQWALVEFEKPVTCPRLCLVIGSRLDADIHANTCRLAFHGVLLHGLEDKNYAESCLPKLRVYKLKHKHGVVERVMDDYSVIGRSLFKKETNIQLFVGLKVHLSTGELGVIDSAFGQSGKFKVHIPGTAALAMVLSSEASVKAGSPIRADGGPPRAEVHVGTSAATPGFRLPSWATGAHTGGLSPESKKILTPALKKRGRAGRGEAAKQEEGAERLEPTQHVELSLSFKRYVFDTHKRMVQSP
The following text describes a protein:
Function:
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.
Subcellular Localization:
Synapse, synaptosome.
Sequence:
MAELSPEEIQLRANQVTDESLESTRRILGLAIESHDVGVRTITMLDEQGEQLNRIEEGMDQINKDMREAEKTLTELNKCCGLCVCPCNRTKNFETTKAYRTTWGDGTENSADHVISMQPRSINQQQPHNSRGPSGGYITRITNDAREDEMDENLTQVGNILGNLKNMALDMGNEIDAQNKQIDRINVKIQIEIALSKPTSERRNSLTIRTYCSCSVTLSLHLQATVFMDL
The following text describes a protein:
Function:
Probable transcription factor. May bind to the promoters of target genes, including micro-RNA genes, in order to repress expression, and acting redundantly with flh-2.
Sequence:
MNLASQISQAKTGNATMEWAKNYVSKLNDGQLALLQKMYADHQAKLKASEDEKKKKEMEELKMKAQQQAILDSLTQQIPIMVDVLRSSTSPDSQPSSSSSVMSSTDEDQITVKDVLIGKINKAQRQSSPNSSKPYTPRGIRERVLFDEHLYVFDKCSYDSKKRFFRCERKNTCPARIHTPFDAERVIHKVQVHNHPPPTTFDLAHYNIDYGKVKSGHILSLNGPQQTKNLLPPSLLTPKSDLEDETLSTKTEQKNASTMNILLSMTNNCDGRKPITLRLPDLFNKISEMEIHDMEMTLTKFLLENRELRTDLISRNGDLPVFFPNAHNDELVLFVADQHENDSVFQMIRVSERNEKSIRQAIQEHLQKVSNRSLMMNISSKINVPLSQQMIDQWRTEEFIRLDSSKPNFWKIHHVSKLQD
The following text describes a protein:
Function:
Plays a role in pre-mRNA splicing. Involved in both constitutive and alternative pre-mRNA splicing. May have a role in the recognition of the 3' splice site during the second step of splicing (By similarity).
Subcellular Localization:
Nucleus. Nucleus speckle. Cytoplasm. Note=Shuttles between the nucleus and cytoplasm.
Sequence:
MGRRSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRRPRSDSRSWSRDRQLRSHSYERRRRRRSSSSSSYGSRRKRSRSRSRGRGKPYRVQRSRSKSRTRRSRSRPRPRSHSRSSERSSHRRTRSRSRDRDRRKVRDKEKREKEKDKGKDKEVHSIKRGDSGNIKAGLEHLPPAEQAKARLQLVLEAAAKADEALKAKERSEEEAKRRKEEDQATLVEQVKRVKEIEAIESDSFVQQTFRSSKDVKKAVEPSEVQHVTAASGPASAAAEPPSTGKEIDPDSIPTAIKYQDDNSLAHPNLFIEKAEAEEKWFKRLIALRQERLMGSPVA
The following text describes a protein:
Function:
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
Subcellular Localization:
Mitochondrion. Nucleus.
Sequence:
MADDSPAQDCPSSPHAHPAVCRVFCTMDTHMDTSEDGDPPITPPPDLKDIAPWRTASDDEADETLGSLFPNFKYGERLRVSALLDEREPELGDIARPGGRPASPHLVVQQRDDEGEEFDRSIMTRALEDNSDSATVTAQKAAALPKVARHISLRLPPAVMTSTLETHTSLLLLISCPFCTLPDRSLPLSQPPSVSLKLSLSNPLPQTLSFKLSLSNSLSLSQTLSLSLKLSPSNSLPQTLPLKLSPSNSLLLALLHMFLTLGTSLLRFSQPRCLLAHERAEQLASREAAEALLESEDSVQQTSNYQNEPPSHRGGLPLACLVNWEDNIIWEHPNGQQASGVNANVHEVYTEIMSSNRDINLADAEDRQKRDEEQQERNRREKEARSRNPKGPTNEGDTKAEKRRRNKSPKVKTVKKQEQERLQLKYGVATDAKHVVPIMAVNSMPKPVVDVSTAVSELPPINEHLCYERWENKIYWTKDDIESSSSEEEPDEEDGQDEDHLAKHKKRHSNLYLDLNDPLFVSDYAVRAPTFKRYMILHQGRGRQYVADWKLERIAKVMAERGPFAEAANQAMGLQRFNVSNDFFYQPRVGTQTEQRHAWRSMLQYHVRHPRPARRVYQKFFPWKQPFMSFRHWHRPLLKPEKKPCVLANGSQVTAQFAPALEEFRRGSKRAFHKTWEISAFYDQLVVLEYAEEYPPLLCRPSMCSELRCYYRKIKANDRTRPSIELGTLAILNTNEESPFLGTLPPGHPVMSIENNLFRAPIYDQKLEQTDFLLVKRNDQWFILRLKTAFVVGQTLPKLEVPAPNSKREQDLEKRHLEMIIINLFNNKMTDPRRSPNDPVLLRVDDVRRTTNSTDSSIRKVLKEYATFKRHAASDFKGAWEWRSVDKKNKIGQELLEGKFSPEDFCAYESMKAAEQRLVDMGYRLANDKNLEAIDETDPGTSKGRRFWSVLLLTLGRTMWVQVDERRLAPWQITKNFVDCIKRSCLLAVTGAGDPTGHSLGYSFLRLANKPAANRRDDEMLPELPESRNKQLGKMSSKDKDLRKLNLKEARELLHQKYGLGMDYLNSLPRWQCISLVRYKANEEADEQGKTLNYSRGTKSSAAEHKMRFTSDSQLVFDNERKSLENDEILSEPETSDGEDGGADGDDDLSDLDGEDAGEDRAEAKAARELRAMISQDRERAQTASQEDAATVNEVASGAAAPERRPQAFHLKIVRKVGNRTHTALIQDPKVIQAYLHQRRHPHTPSLRRQQTKGSGGNGRRTESDDDNDEDDDDYQDDDDGRSVVSTASRRSKKSTKGPTQRKATSRSKKRGADGASSVASKRSNLQAESPPAPRELNVNSVINVALQKLANYDQSKTFQTDATAPSGMAIMGLRRLTERARRSEFETAGEFVQALRQLVDLKGDSNPAIRALGNRMITVAEEEFKKHNVVTVAHVKKLREQTALPMKLCREALEASNDNVDAALQWLQDNEEARGQQALGKLAGRSTAQGRLAIAINEQAAAVLQLNCETDFVARNEAFGETSRLGAESLAQWLAQNKAEGNDAHLLSAEEVAAVPVAESDTLADRVKALVAAVGENVALARGAGFVKSGATFGSYVHDNGSYAALVLAETSGADRHVSEQHNPLLDTRAMLVHFLSSRATSEALNKVAQHAAAIDPTGDSAAATVENLLSAPYVFNSSQTVAEFIKSAAKDQTVTVQNVLRWERS
The following text describes a protein:
Function:
Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSLLTHLLVCIFGSASWVAINGLWVELPLVVPKLPEGWNLPSYLTVIIQLANVGPLFITLFHRFRPGCIPEVPVIFVMLVLGTIACLLFAFLWEKTSVVAGVPHSTAFLVLTFFLALVDCTSSVTFLPFMARLPPQYLNTLFVGEGLSGLLPSLLALTQGTGIKICVNVTNDSITTEPPSIAKASFITGIPNMTLTPDLIARGPQLTNCYLSANFSTFVYFLLLSGMMACCLAAFFGLTRLSKQWELSTEDLLVSQVTLTTFKLQEDSAGNSKRDSCSLPPVPEEKKKAVWSRAQLAFIYALVAFVNALTNGILPSVHSYSCLPYGSKAYHLSSVLGSITHPLVCLLSMFLPDMSLPWLGVTTMVGAGFAAYNMAMAVLSPCPLLKGSRWGEAIIVISWVLYGGILSYVKVMTGVHLRKMNQSALLWCGAAIQLGSAFGAIIMFPLINVLHLFKSASESSQQCPI
The following text describes a protein:
Function:
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MSDDSKIKEVYQLLRHIQPSKIEHRREDSITLAPDLEDEILQTVDVPLKIVQDEVKNAPYIACEFNRDLDSYRSPISNKYFPSLPDGQKLPKRLRNMEIKANTAFGAYTHLYYNGGICSVYFWEIDKGVFGCGVFIKNEIDTELRSGEHIKGSINCADTIEVDETDETATYTLTSSAIVNVELDVGIGTPLTISGSTSDRKVKKAKWGNDNDHIVNIGQLVESNSANFKDTIDGIFVGKMKQIMDLLANNDGRAQQAAMAEAFAAQARARGLK
The following text describes a protein:
Function:
Chaperone required for efficient photosystem II (PSII) assembly. Binds to psbA during de novo biogenesis of PSII.
Miscellaneous:
MISCELLANEOUS: Accumulates even in dark-grown seedlings.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Sequence:
MAVATAPSLNRHFPRRISNLYSRVKQRRPWLPPGDATLFNSRRNWDSHLFVYASSSSSPSSSPPSPNSPTDDLTAELCVNTGLDLFKRGRVKDALVQFETALSLAPNPIESQAAYYNKACCHAYRGEGKKAVDCLRIALRDYNLKFATILNDPDLASFRALPEFKELQEEARLGGEDIGDNFRRDLKLISEVRAPFRGVRKFFYFAFAAAAGISMFFTVPRLVQAIRGGDGAPNLLETTGNAAINIGGIVVMVSLFLWENKKEEEQMVQITRDETLSRLPLRLSTNRVVELVQLRDTVRPVILAGKKETVTLAMQKADRFRTELLRRGVLLVPVVWGERKTPEIEKKGFGASSKAATSLPSIGEDFDTRAQSVVAQSKLKGEIRFKAETVSPGEWERWIRDQQISEGVNPGDDVYIILRLDGRVRRSGRGMPDWAEISKELPPMDDVLSKLER
The following text describes a protein:
Function:
Directs RNA polymerase II nuclear import.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MEAGRTAVLRVKRKLGTEPAEALVLACKRLRSSAVELETPKTSPEGLERAAENNVFQLVATVRSQEEPVQPLLRAALRPSQGSQQRIRHHLRASAREIRQEGRYRVVFSRRSSGIPSDSLESEDASGTAKAADDANFQLLDLVHEEDAEVAAAAISCKKSDPDVILCNCVELIREGLNVSQCGPSSGHQKEQKDDFVYDIYCLERATPGWIENILSVQPYSHEWELVNDDQQPEDIYDDEDDENSENNWRNEYPEEENSDEDEDSRGSDNYSSSEERDNSRQPMWSKYPLDVQKEFDYDSPHDLDSD
The following text describes a protein:
Function:
Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.
Sequence:
MTPEGRMHGLFLGIDCGTQGSKALLLDAGSGRTLGLGSAAQRPPEGRDGRREQDPADWLEAMASAVRMALEEAAVDGREVRALAVSAQQHGLLLLDAEGRALRPAKLWCDTESAAENRELLEALGGPAGSLERLGLVLAPGYTLSKLLWSRRRFPELFARVAHILLPHDYLNHWLTGRVCSEAGDASGSGYFDVRRRTWASDVLELVEPGGRLAAALPELIEPGACIGNLRPEAAAALGLAPHTRVAGGGGDNMLAAIGTGNIRPGLLTASLGTSGTLSAYAERPLVSPHGELATFCASSGGWLPLACTMNLTGACGLVQDLLHLDLDEFSRLAAQAPVGAEGLLMLPFFDGERVPALPHASASLHGMTAANLSRANLCRAVLEGTAFGLRYGLDLLRASGLPGEEIRLVGGAAKNPLWRRTLADLLGLPLVCPRQTEAAALGAALQAAWSLGRESGAGESLEALCRRCVALDESTRTQPQARQQAAYEQAYRRYLEHLPPR
The following text describes a protein:
Function:
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of early, intermediate and late genes. DNA-dependent RNA polymerase associates with the early transcription factor (ETF), itself composed of OPG118 and OPG134, thereby allowing the early genes transcription. Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.
Subcellular Localization:
Virion. Host cytoplasm. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle.
Sequence:
MENVYISSYSSNEQTSMAVTATDIRELLSQYVDDANLEDLIEWAMEKSSKYYIKNIGNTKSNIEETKFESKNNIGIEYSKDSRNKLSYRNKPSIATNLEYKTLCDMIKGTSGTEKEFLRYLLFGIKCIKKGVEYNIDKIKDVSYNDYFNVLDEKYNTPCPNCKSRNTTPMMIQTRAADEPPLVRHACRDCKQHFKPPKFRAFRNLNVTTQSIHENKEITEILPDNNPSPPESPEPASPIDDGLIRATFDRNDEPPEDDE
The following text describes a protein:
Function:
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
Subcellular Localization:
Cytoplasm.
Sequence:
MYPKKTHWTAEITPNLHGTEVVVAGWVWELRDIGRVKFVVVRDREGFVQVTLKAGKTPDHLFKVFAELSREDVVVIKGIVEASKIAKSGVEIFPSEIWILNKAKPLPIDIWSETPDLATRLKWRSVDLKRPRNLVVFTVASAMLRSIREVLYGEGFVEVFTPKIIVTSTEGGAELFPVMYFERVAYLSQSPQLYKEQLTASLERVFEIGPAYRAEKHNTDYHLNEFISVDAEAAFMDYNDIMDILEKIMRRLASTVSEYAPKLEEVGIKALMELSNIPRVDYDEAVDRLRQLGYAVNWGDDFTVEMQKALMKYYGPVYFIVNFPASLRPFYTKRKDGEKSESYDLIINGIEVASGATRIHKRDELEEEMKKRGLDPRLFESHLSVFDYGMPPHAGFGLGFNRLVTALLGLDNVRHATLYPRDRYRVEP
The following text describes a protein:
Function:
Component of the plastid division machinery. Required to mediate the dissociation of ARC5/DRP5B from plastid outer envelope membranes (OEMs) at the midplastid constriction site in the cytoplasm, thus triggering ARC5/DRP5B ring turnover at the chloroplast division site. Binding to phosphatidylinositol 4-phosphate (PI4P) modulates negatively chloroplast division.
Subcellular Localization:
Plastid, chloroplast outer membrane; Single-pass membrane protein. Note=Plastid equatorial positioning in a discontinuous ring mediated by CDP1. Colocalizes with ARC5/DRP5B at the chloroplast division site.
Sequence:
MGEMEIEEIEAVLEKIWDLHDKLSDEIHLISKSHFLKSVKPSNRSEKRKNPHGNSGEDKRPGYVFIKGFAVDDNDSTIQEAKSLNAIRTALENLEDQLEFFHTIHTQQRTEKDVAIARLEQSRILLAMRLAEHHGKNYGVLEEALAFVGSIKSNSHYVSPDHLYDSSRNPDGANSIPDGIESNFVINAFASTFGFAKRALGFNHVKGVLGNAAIFAISVVAMLHLHQVATSEHHLQKKEDRFYRSQQRKTYGRDKSSADRSLDHLDVMMARG
The following text describes a protein:
Function:
May be involved in transcriptional regulation. Required for progression through late erythroid differentiation. May be involved in vasculogenesis.
Subcellular Localization:
Nucleus.
Sequence:
MYQIPVKNLTKLRRPRKRVKSILCDIGMQQCQDMLETYKCFDAGDASFDNTEWDDFTDGHVGKKKKKYPYRSQSLCCSLCWYSSRSVPTFRSHIHRCHWKNLDGACLLMCPYCPFVSSPKVTEQHIQFFHMLPSRAHQSHPSHTLAHTPKTISVTVSADAADDRYTCATCGYHDSLLYVMKKHVLVNHFATLLDRYFGLGSESAPMAGPQIRDGTPVKYHCKLCKLPAETIEHLLYHILSSEKHKELHWQIMPCIIEKECMNQMVGLQNLLNLAPKSMQPVTLFARPNYMPQQTQQTNGNGTVLLAGPSNAAALFCSPGAGQMFLSPQTQALLSGTTVAALQNAPHPQSPGGMSQVLPTSPVVKPLNMVMPNMPQNTPKTLPLTMTVPRLPPPQQGPQVLLPPGVQVNLPGEMGVHSPFLVTQGLQLNQSVPRAPLITSQSVRFIPTGNKVNGVPTYTLAPVQVTVPVHGGPPQMVLAQNQISQPPNSAVVTPGLMPPVQRAMNKNSRPNELAVQAPFLKKHDNQTVKCLRCKILLTEQGIFQHLLHGLKCLFCPQMFYSFKQIMEHSKKEHSLKVKDNRLYIKEQFSLDCDDEGNLIFSTFNLNTDVPKDLLDNRELNLALVTSTKDKIYIKMYPDKAEYTTMLKSAPNACPFCQVKLQNPEDYELHLQTKHHIVPTIHAILKTPAYKCIYCFGVYTEKSTPKTISIHVQRCRCAPKAVKEAERKLNPDTSESHDGDVCSSVQMPASEVTFQGAPEFPKPKKEAVTPRNRRRNTKASKTGTLVPETPVTLVLEPMGMERTSFEDRKDFLSQYFHRKPYVTKTEIELLASRLWINKADVKAHFNSKLTKCLKAIQKKRVCVRLGFKMIEVNKLKHNLFIPEVKPVKRKDPNEVNLSSLVPGVTVKTEQVDATTQHPLFIPEVPVTIKKEEEVCEIDHGFIIQEVTVKQEEVDEMEDALCTNG
The following text describes a protein:
Function:
Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MCQSPLHDFLHGLPKCEHHVHLEGCVTPELIFQLAEKNNIQLPNPATHPAYASVEALRARYAEFTSLNDFLDFYFHGMSVLHHQSDFEELAWAYFQKAHADGVHHAEVFFDPQVHQARGIDYETVVSGFTAGCKRAERELGLSTRLILCFVRHLPVDSATKLYELALASNHFESRVVHGLGWSSSEVGPPKDMFREIYASASGKGIRLTAHAGEEGDPTYISTALELGARRIDHGIRLVEDPELMERVAREGIMLTVCPLSNVRLRCVQSVEQVPIRKFLDAGVKFSINSDDPAYFGGYILDNYCAVQEAFQLSILEWRVIAENSVNESWIDEARKAELLKRIDDHVQKHTVVA
The following text describes a protein:
Function:
The GINS complex plays an essential role in the initiation of DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MSSNDQQRGGVADKALQLVMEMKRNPDVLPPYNADLVRQCQKKIDELFHKNAAVVERMRNGLEHDPSLLQPRLAAMCHIRRCMMAYVNERKNRIRSFRWRYGGALPASVRNALCEAEIQFFNEYSSTLARFQSNLGEAGVNLLLHTAPPKTLFVQVRTLEDYGEFETSDGTQVQLTKDSLHSLPRQDCEMLIRQGVLELVH
The following text describes a protein:
Function:
Acts as a component of a SCF E3 ubiquitin ligase complexes.
Subcellular Localization:
Nucleus.
Sequence:
MENLPPELFLRIFCLLDHHNLATAQLVCRKWKMLGSENSLWCDLFIERWGSDQATFYAPDDSKSWKHVYMVQDRCDRNGLGLKIIREGDDYYLIHQGEIQRHLGSRKSKMEEISESFNCKDDREESNLSILDKILFFIGDLESASVQVKRSRLV
The following text describes a protein:
Function:
May act as a carbohydrate transporter.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MNMSSSSPILLMFIFSIWMLISYSESTDYLVGDSENSWKFPLPTRHALTRWASNYQFIVGDTITFQYNNKTESVHEVEEEDYDRCGIRGEHVDHYDGNTMVVLKKTGIHHFISGKKRHCRLGLKLAVVVMVAPVLSSPPPPPSPPTPRSSTPIPHPPRRSLPSPPSPSPSPSPSPSPSPSPRSTPIPHPRKRSPASPSPSPSLSKSPSPSESPSLAPSPSDSVASLAPSSSPSDESPSPAPSPSSSGSKGGGAGHGFLEVSIAMMMFLIF
The following text describes a protein:
Function:
Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate. Is essential for the growth and pathogenicity of M.tuberculosis, and for the generation of the bacterial cell wall.
Sequence:
MGLSIGIVGATGQVGQVMRTLLDERDFPASAVRFFASARSQGRKLAFRGQEIEVEDAETADPSGLDIALFSAGSAMSKVQAPRFAAAGVTVIDNSSAWRKDPDVPLVVSEVNFERDAHRRPKGIIANPNCTTMAAMPVLKVLHDEARLVRLVVSSYQAVSGSGLAGVAELAEQARAVIGGAEQLVYDGGALEFPPPNTYVAPIAFNVVPLAGSLVDDGSGETDEDQKLRFESRKILGIPDLLVSGTCVRVPVFTGHSLSINAEFAQPLSPERARELLDGATGVQLVDVPTPLAAAGVDESLVGRIRRDPGVPDGRGLALFVSGDNLRKGAALNTIQIAELLTADL
The following text describes a protein:
Function:
Plays a role in the control of cellular growth (By similarity). May have a role in epidermal development. May act as a receptor for Sonic hedgehog (SHH).
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MVRPLSLGELPPSYTPPARSSAPHILAGSLQAPLWLRAYFQGLLFSLGCRIQKHCGKVLFLGLVAFGALALGLRVAVIETDLEQLWVEVGSRVSQELHYTKEKLGEEAAYTSQMLIQTAHQEGGNVLTPEALDLHLQAALTASKVQVSLYGKSWDLNKICYKSGVPLIENGMIERMIEKLFPCVILTPLDCFWEGAKLQGGSAYLPGRPDIQWTNLDPQQLLEELGPFASLEGFRELLDKAQVGQAYVGRPCLDPDDPHCPPSAPNRHSRQAPNVAQELSGGCHGFSHKFMHWQEELLLGGTARDLQGQLLRAEALQSTFLLMSPRQLYEHFRGDYQTHDIGWSEEQASMVLQAWQRRFVQLAQEALPANASQQIHAFSSTTLDDILRAFSEVSTTRVVGGYLLMLAYACVTMLRWDCAQSQGAVGLAGVLLVALAVASGLGLCALLGITFNAATTQVLPFLALGIGVDDIFLLAHAFTKAPPDTPLPERMGECLRSTGTSVALTSVNNMVAFFMAALVPIPALRAFSLQAAIVVGCNFAAVMLVFPAILSLDLRRRHRQRLDVLCCFSSPCSAQVIQMLPQELGDRAVPVGIAHLTATVQAFTHCEASSQHVVTILPPQAHLLSPASDPLGSELYSPGGSTRDLLSQEEGTGPQAACRPLLCAHWTLAHFARYQFAPLLLQTRAKALVLLFFGALLGLSLYGATLVQDGLALTDVVPRGTKEHAFLSAQLRYFSLYEVALVTQGGFDYAHSQRALFDLHQRFSSLKAVLPPPATQAPRTWLHYYRSWLQGIQAAFDQDWASGRITCHSYRNGSEDGALAYKLLIQTGNAQEPLDFSQLTTRKLVDKEGLIPPELFYMGLTVWVSSDPLGLAASQANFYPPPPEWLHDKYDTTGENLRIPAAQPLEFAQFPFLLHGLQKTADFVEAIEGARAACTEAGQAGVHAYPSGSPFLFWEQYLGLRRCFLLAVCILLVCTFLVCALLLLSPWTAGLIVLVLAMMTVELFGIMGFLGIKLSAIPVVILVASIGIGVEFTVHVALGFLTSHGSRNLRAASALEQTFAPVTDGAVSTLLGLLMLAGSNFDFIIRYFFVVLTVLTLLGLLHGLLLLPVLLSILGPPPQVVQVYKESPQTLNSAAPQRGGLRWDRPPTLPQSFARVTTSMTVALHPPPLPGAYVHPASEEPT
The following text describes a protein:
Function:
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
Subcellular Localization:
Cytoplasm.
Sequence:
MCFNQRILIGSISTEQLNKTIVIIGWIKRIKKLGEINFIIVGDKSGTIQVTCKDKEQIQQLTREDIVIVKAKLQRLDSVRFELINPTIKLFSKSKTPPLIIEDETDALEEVRLKYRYLDLRRRLMQKRLLLRHQFILAIRNWFNQQGFIEIETPTLSKSTPEGAQDFLVPARIRKDCFYALVQSPQIYKQLLMIAGVEKYFQIARVYRDEDSRKDRQPEHTQIDFEISFCNQKMIMNLVEKLFFSVFLDVFQIKIKKTFPVFKFSELFERFGSDKPDLRYGFEIKDFTSLFQDHQNQFTKLIEAKGIIGGIELTNIELSTDKIKALRKIAKDHDVSLEVHNKNNSTLKTSIKCDEKNTLLLVANKSKKKAWTALGAIRNELKYHLDIVKPNQYSFCWVVDFPLYDFDEKTNQWISNHNIFSKPKQEWIDNFESNKNEALSEQFDLVLNGFEIGSGSIRINDPIVQKRLMNSLNIDPNKFAFLLEAYQYGAPVHGGMGLGIDRLMMILNQTDNIREVIAFPKNNHGIEVHTNAPDKIDKEEVKWWIKELVK