lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. Binds specifically to double-stranded DNA.
Subcellular Localization:
Nucleus, nucleolus. Nucleus. Chromosome.
Sequence:
MGDMLEFNEIYQEVKGSWNDGRLRFSKQNVVYKSNKTGKVDSIPAGELNLAQWRRVCLGHGIKLGTSTGHVYKYDGFRDTDFEKLSEFFKANYKMELAEKDMCVKGWNWGTAKFSGPLLSFDVNDNTAFEIPLSNVSQCATGKNEVTLEFHQNDDTEVSLMEVRFYVPPSQADERQESVEAFAQNVLSKADVIQATGDAVCIFKELQCLTPRGRYDIRIYPTFLHLHGKTFDYKIPYTTVLRLFLLPHKDQRQMFFVISLDPPIKQGQTRYHFLILLFSKEEDINLTLNMNEDDVERRFEGKLNKNMSGSLYEVVSRVMKALVNRKITVPGNFQGHSGAQCITCSYKASSGLLYPLERGFIYVHKPPVHLRFEEISCVNFARGTTTTRSFDFEIETKQGNQYTFSSIEREEYGKLFDFVNAKKLNIKNRGFKEGMKGKIDDYSDSDEDKHDAYLERMKAEGKIREEGNDSDESDAESDESFNPGEEDDDIAEEYDSNASASDSSDEGDDSEDESSKKKKPKKVVKEKKERKERKPRKEKKQKDAGGPKRPMSAYMLWLNSSRERIKAENPGISITEISKKAGEMWRGLGKDEKEEWDTKAGEAKRQYDKAKKEYKESGGGSTSSSKKESKKSTSKKEEKKRKSAGGDKDKERGGNDSFKSKEFIETSEESSSDSDHKSKSKRKKESDDEEEEAVSTPANSEEESD
The following text describes a protein:
Function:
Acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone. Acts by binding to angiotensin receptors AGTR1 and AGTR2. Also binds the DEAR/FBXW7-AS1 receptor; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis; Is a ligand for the G-protein coupled receptor MAS1. Has vasodilator and antidiuretic effects. Has an antithrombotic effect that involves MAS1-mediated release of nitric oxide from platelets; Stimulates aldosterone release.
Subcellular Localization:
Secreted.
Sequence:
MNFQSIWLCLSICFGYSLSNRVYIHPFNLFAYNKSECEKVEKQNHTIEVFFTPVSVETNISPEEETLGSTGALETKLLGTVERQRVSILPSLVNDAGFRCFNGWKETHKDDTILMSFTNLFGSLVSFYLGAPTHTSADLQAFLGFAHQSGDQDCVSKVDALKVISTLKHIDNRLFSKDNNIESLKMTCLFISEDVPLSETFIHNLIPSADKFYVRGVDFTNPTKAVDLINKYLNTRSTKKGKYILTPVDASANILFMSYIHFKGKLKNAYLIPEPQDFWVEPGRKIATPMISLSGMFHYKQDINMNQIIVKVPLGENDFMLLIQPINENTLENIESSLSWHTFLKWLENLSSRHINLSLPKMEIESSYDIQDILSNMELSYLLGKKADFTKISNVELTVGKIINKVHFELEESGEDANKAQDIPVNKNDQEPMEIKFEKPFYFVVFEGTTKALLFIGRVKSPLSTI
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MGKSKKQTARSATSDWTVVNKEEWAQQQQLQQAEAELEEQTSKLEAPRRLTKRDKRRGAQRVRRAGWNLVDVPEETMWNFSQEGFCRLEELDGNLIDEYQNGVLAINSEAPATEPSAADPEAADPSEKKKKKKKRKSKSKKVDAQEDASADPEGLNVIQADVVDAHTLKDQVAQKTRTKKGKAAAKRAGASSDLSDNGQAQPSEAHSRPAKKSKSIEPSDMDDEDDHDDAPSGKLSTTRESTDKKKRTDTTEHHRTPHLELGRFMDLTPVVGMCTPEDVTTSQPLADEDLAAWTVLQLDRELAEAVVRRGFTAPTPIQQAAIVPAVRDYRDVIAAAPTGSGKTLAFGLPVLQHILNRRARGRSTAGLQCLILTPTRELALQQSLWQIQQHLKPLATPLSVRVTAIVGGMALVKQERLLKAKPEIVVGTPGRLWEIIQSGHVHFAHLDSLRFLVLDEADRMVERGHFAELDKILARLPRPTQPAFPTEEDAYLQRVRENARRDGTPNVQEVPSNVEEPSATQSDGRKRSSKDKLEEEVLMDVFGTETADDRITQMLLKLRRDGMSFIPTAMDQAHDDSEDEAEDADEAVETDEGADSDDESDAAEAEDDHEQPTEDSDRAQRKTPAADSTLTQLEDKKTQGPDEVETQLALEQNKVKRQTFLFSATLLPQFQKGGRKGQRQAGGKGATDTSIERALSRVVQACGLRKSFAQLDLSTQIMAGEQRLARGLQEVRITCPSTDKEVYLYYFLRRFPGRTLVFVNTIDVLKRLKTVLDLVGLNPQALHAQMQQRLLNFRQRLKFLDRFKEQDNCVLLATDVAARGLDIQNVQYVVHYQLPKHADSYVHRAGRTARGTAAGLSVVLQSPEDQQAYANIHKTLNRTTDMQAFPVELGFFKGIKALLGAAVKVERLQRQTNKPKNNNNWFAKAAREMDIELDDDLLEEESAASQKTAQQLADCKARLKTLLGQPIMMTGASRHYVSSGNAERAFLTTKHHMRKSLLSLSLSLSLSLSPSLSLSLFFLSLSFSLSLLSFSKHARTMDYHL
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Sequence:
MDELRDIRTTGPEDVLNSVDPYRYTSQIPNGKSNNGLNAKMNGNNTLTNMINRSIAKNMGQNASSGSMRRSMRQSLRNSLPRSSIGPQQQQQMNSTQNSTYHNTARDPRPLRDKNFQNLLQQEIFSYLTDQKFDVETNHPISLKSLKQPTQKDFIYMFKWLYLRLDPGYVFTKSLEHEVYSILRTIHYPYLATINKSQISAVGGSNWPKFVGMLHWLVIINKKLDECLEHLDVSINNQVTQDITVLNQPLKTAEEQEKKQEKYELMVERLFIDYITESYKSFLRLEDDYEPYLHDLELSFQRFVHIIETDIAQLTSTTEHLSVECESIVAKNYELKNIKEKNTGLEQEYKRLSHGVQITQAKSKEWPDKLKEIEDEIDKKKRDIRQVSLQIDELTSVLKRKNISGEEIEHKNKESDSISKSLDTVSSRLDQFTGLVRQQRLETESVYKNLQDTLKQYKSATEGLVIARKNLGDHIDESSIELVLPSDLMSEEMIGLTVEELIGDKKSFTDPIKKNLNKIAEDIKMRITNIQTENSKLQIKLEDLRNEITTKNEDLDQLEQQLSSIKSEYEEYRQESQSQLLSQNIKIEKLERKIQNARVESQQKISSIEREAEETRLKLEELKLLQNRERLELHNKVIQLIEYVSNFKINTQSSIEELQNATQKELQRLQTEV
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Nucleus envelope.
Sequence:
MTVASDDSPKEARGIPFLDQKSRKLANELLEPCLPFIQFNLGEIEQRAKHYLNTVPTSKDGNTKAHYLLAGSGINAEQTWKKIESLSLQVRPPTTLELSFTDVDMFLKYHREKNVLNSLEALVQNTQIAFDQYLEEEWRSKAAKSRPSFDNILLENKKRVSFYPFSVQRSQKFASTLKMCLEEEALHGFQSKLVSSFCEVAREFAHDTKSLLLYESWKLLSSVILDKDSVTVFGNKGIISKAFDIETEDGSVNSRFYQRISDCSRKFLEAQFFEVLNKEIAKTPQAALVGGVPSIRNKIRAYLNIRLLRNGVWINPDLEIIQDVPIWAFIFYLLRCGFLKEAVDFTEENRDLFEKVAEKFPFYINAYAKAPNGILPRQLRSQLFSEFNQTIRLQESSDPYKYAVYKIIGRCDLSKTSCPSICSVTEDYIWFQLILSREFTEKSVSAHEFFSLEDVQHILLSYGSDYFTNNGSNPVMYFFLLMLCGLYERAINFLYPYFPTDAVHFAITCAYYGLLRTAPSSSVVSNEPGKIQSMLVETKSGKPSLEFDRLLIDYTQTCQELSPVMSACYLIPMCKIDKYISMCHKSLCSLVLSTRDYVNLLGDIRGDGERTPSFLENHRSLIGLSSVKEYLSKITLTAAKQADDQGLLSDAILLYHLAEDYDAAVTVINRRLGSALLRFLDQFVFPDKLISLTKSMMDVYNRNPSLYAKVDYKNRETTNLLLLTVEAFNAYTNKDYEQALSSLQQLEILPLDPLDSDCETFVVRKLAKEFRFLNENLLQNVPGIVLIAMNSLKELYAKQKSSSFGNDAISVDKLRLYRQKARRIVMYSFLIEYRMPSQILEQLNRCEIEMT
The following text describes a protein:
Function:
Plays a role in store-operated Ca(2+) entry (SOCE).
Sequence:
MASPGPPGAGQGQEEEERAGVSAGHQAEVLQQAQELFVLCDKDAKGFITRQDLQGLQSDLPLTPEQLEAVFESLDQAHTGFLTAREFCLGLGKFVGVESVPGRAPLRTPEETFESGTGGSLEEEDDVETFYTSLEKLGVARVLGEQWAVRTLWVGLQRERPELLGSLEEILMRASACLEAAARERDGLEQALRRRESEHEREVRGLYEELEQQLREQRQRRQSQNPPREEERGHLELELQTREQELERAALRQRELEQQLQARAAEQLEVQAQHIQLQRAYEALRAQLDQAQEQLIRLEGEAQGRQEQTQRDVVAVSRNMQKEKLSLLRQLELLRELNLRLRDERDACETKLLGSSHRKALAIAHKPGPIYCCCCCGWARPPRRGSGHLPSAR
The following text describes a protein:
Function:
Acts as the pointed end capping protein which maintains the length and dynamics of the actin filament. Blocks the elongation and depolymerization of the actin filaments at the pointed end (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MSQAKTDYYSEEKTFSAPSANSQQGTQLPSKVYNKGLKDLEDNDIEGLLSSLSIDELEDLNNDFDPDNSMLPPSQRCRDQTDKEPTGPYKRDNLLKFLEDKAKTEKDWEDVCPYTPGQKRGKVYDSDSGRNSEEPENGKMEMPIEIDLDDDEEELECALVTAPEKDLVDLAGILGMHNVLNQPQYYNALKGKTQDESTGTTFNGIMQSYVPRIVPDEPDNDTDVESCINRLREDDTDLKEVNINNMKRVSKERIRSLIEAACNSKHIEKFSLANTAISDSEARGLIELIETSPSLRVLNVESNFLTPELLARLLRSTLVTQSIVEFKADNQRQSVLGNQVEMDMMMAIEENESLLRVGISFASMEARHRVSEALERNYERVRLRRLGKDPNV
The following text describes a protein:
Function:
Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology; Involved in a reduction step in the biosynthesis of the plant steroid, brassinolide.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane.
Sequence:
MDLNAGTLLGKSGVEPALEAWCFLATWAMIGTAVPVFLALIAGITAPYGRYVRSGWGIFLNARVAWLTQEIPSLIVFVVMLLLFSTPDSFLQHPLSARTVLSGAFCAHYVYRSIVFPFIIRGGKPTPLSVWAMSFVFCIWNGFIQGWCFARQMTSDTPVWNPRVMVGLAVWLFGWLNVMRADLILINLRKPGESGYKIPHGGMFNFVSAGNYASEICEWSGFALAAGTLPAAAFAMFAFCNLSPRGHHHHRWYREKFKGEYPASRRAVIPFVW
The following text describes a protein:
Function:
Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
Subcellular Localization:
Nucleus.
Sequence:
MPNVYLPQILWHSKDNKRSDRIYSLDIQPYPNYYSVKKLNRKYELFIKYLKEKGKIECNKFDTLEEKQKIINDSTLPSNNNYNNSSNNNNNNNKYETLKLDKELNQGNEDNIIKTVIGNNTEVSNNNLLDDTNNKLNEIKTNTSTEDHQEHNLVNKKNETNSSSNDNISHNKTPMQSNKLLTSLQDDKTKKKPIKFNIATCGADEFVHLWRIFIKDDISIKCLGRFIGHSGEINCVRFNKNGRYIASGGEDKFLYIWEKSKKPKNIPLGYDISFLDYKEWWNVVGSFRCSGVINSIIWSNNDTLYVANEDNNINIIDFVKNTNCKVQVLEGHSGIIQGISFDNNYEYLASLSADQTLKIWKKKNDGKSWKLENSIKNIRRDELDKLNNACTTCTEYDFPDKNNTDKYESNTLKQENKKLINYDLLEQEAYKKKTKNKKEKADEDEEEANNNEDVEEQQTDVGEEHIEGHLNNNIVLNSNINKMNNSNNLKMNNSNTIKMNNSFNQENNVKPYQQIHTKFMSKKHLEDGEEEQEEEEEEKKFKRSLFSSEEMLPSFFRRIDFSPNGEFLITPSGIQFEQVEKVNEKNNKTDENAKPNYEIKAYSCFYIYHKNLFLKYNIPFFTIFSQTSHFLVAKFNYNTFKLRTEQNILKRCYEHFLNNLSDVNDEDISNSNKKRKIYDDNLKLNELMYNEKLIKLNYEKTLLYNHIDIPDDVSQIVSSTISESDVEFNEDKVSLKELSAENCLMKNTERNEDGNDEDNTEENVEEKKDDIKEEKQDDLKEEKKDDSKDDSKDDSKDDSKDNSKDDSKGDSKDDSKGDSKDDSKDDSKDDSKDDSKDNSKDDSKDDSKGDSKNDSKDDSKNDSKDDTKEESKKENELDINNKLNADEEEGKNDIMDKYNDNNDNVEILNEQDASSELKDKKEERFIYTLGTFDGSVYFYDSEILDIPISIVKNIHLCPITDISWNNLGNVCACSSSDGYVSFYHFNNNELGNIKSYKNYYLDKKCNDLTFDQNYFKNTFYDEVEFLNKDESNDYTSSEDEFDDHNLIPPKEETKVKRINLIVGNAANFVLSQNTKK
The following text describes a protein:
Function:
Transcriptional repressor and activator. Binds to CACCC-boxes promoter elements. Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion kinase (FAK) (By similarity).
Subcellular Localization:
Nucleus.
Domain:
The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors. In KLF8, the motif is inactive.
Sequence:
MDKFIDNMDVRIKSESGSMQVFKQVTGPVPTRDPSARADRRNMTSPSFLAASPMENPALFNDIKIEPPEELLESDFNMPQVEPVDLSFHKPKAPLQPASMLQAPIRPPKPPTAPQAIMVPTSADTVTSAAIPTVLTPGSILASSQGTGGQPILHVIHTIPSVSLPNKMSGLKTIPLVVQSLPMVYTSLPTDGSPAAITVPLIGGDGKSAGSVKVDPASMCPLEFPSDSDESAIESGSSALQSLQGFHHEPATMVHMQGEESLDLKRRRIHQCDFAGCSKVYTKSSHLKAHRRIHTGEKPYKCTWDGCSWKFARSDELTRHFRKHTGIKPFRCTDCNRSFSRSDHLSLHRRRHDTM
The following text describes a protein:
Function:
May play a role in activation of the SPEC2A gene, binds to the TAATCC motif with high specificity. May have additional functions in the developing embryos.
Subcellular Localization:
Nucleus.
Sequence:
MEALSDLACREIKMESHSPQDSKDLNVKPVKLERLGMSSSPPRLTIDCGDTGRSPVPSHMEPPGGARVPYPMHLYPYPYAYSNPMYGEGALPAPDRHLPPTQQHPMFQPQVLGPMTSERPHSNGIDPPRKQRRERTTFTRAQLDVLETLFSRTRYPDIFMREEVAMKINLPESRVQVWFKNRRAKCRQQQQQQQNGPNSNNTTNKPRPAKKKTPPPTPRENDAPTTTSSDTPPFKASPSVSSSMPNNNSIWSPASIAPQPMSSDHLAANMSNNSCMQHSYTMPNAQPAAGYTAQGYQSPYFGAGLDYLSHMPQFPGSINHQMAASAMNNGPMTTMASQLPPPHHAHMPMGAMSSAECIDGKEQPQWKFQSL
The following text describes a protein:
Function:
Key enzyme of fatty acid beta-oxidation. Able to isomerize both 3-cis (3Z) and 3-trans (3E) double bonds into the 2-trans (2E) form in a range of enoyl-CoA species, with a preference for (3Z)-enoyl-CoAs over (3E)-enoyl-CoAs. The catalytic efficiency of this enzyme is not affected by the fatty acyl chain length.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MIGLTLIHHTSPQLQKYCLSRVQTPSVLASLFSTASAKDDFTHISVNEESGVAMLMLNRPPANSLSLEMNEAISTSIKQIEANPKVQSVIIASSNPSIFSAGLDIAELVEPDKDRLPKFWNSLQQVYLDLYGSRLATIAAIQGHAPAAGCMLAMACDYRIMCAGHGDDEVDGKKRRKHVPTIGLNETQLGIAAPPWMGQLMVRTIGFRMAERALALGTLFQPTDALKVGLVDEVGNEQVSNPLMQKAYREAALYAKIPPQARVASKMVTRSDCLQDMFATREADNDFFCGFIGQDEVQKNLKGYVEALKQKSKKV
The following text describes a protein:
Function:
Transcription factor that negatively regulates pleiotropic drug resistance genes, including the ABC transporter genes CDR1, PDH1, and YOR1.
Subcellular Localization:
Nucleus.
Sequence:
MSGPDKGSDSGQTANDPKQKKARNGQMETYSCARCRKLKKKCPRQLPECSNCLKAREPCNYPGRAPRRTKKELRDAIMKGEVLPSMRRKHRKIEKELKTADLRHLESVDDRPVNQVMGGSMPPLGAYRGGEQQYNNGPPISGIDGNDSINRGKAQSVGSYQILPPQRKSKLVLDQNPKFVHSQSSALKTNEYPVPIMSPHIANQVYPEGVSSLISALNTMNDNVSANTPIALSYLQLQKLHQEQQQIQQQQIQQQQQHQHLVQQHLQHVRADATSILPPVTSQTVYTPIPGPRTSQIPFGFTHGYTASAPPPLMQPYSMPTSPFESREKQQQFDNIQYHPVYKIPPIAARQSPIDEIIGIENGSISIDAGSITREVVNSRMKGPHSTSWVNEDGSPKPIKKSLLEKFVSAYFEHNHRLFPMVDKVTFLKKLATINSFESIEMLAVNNPELPKTFIFEIYMIMAIGCTTLQRAGKLTTDEGHLYEHLAYLAMRNFRDILHQQDITTLRCLILLGIYSFFEPKGVSSWTISGIAMRLAIELGLNRPLTAKEMGDMSAVEVESRYRVFWSAYCFERVVATSLGRVSAIDDEDIGIPLPRALYDSEKEDIEVTNLIISLRKMGGKIYKEVHSLSAGRKDITMEQKQLIIQKLRKELDDIYEEECEKRRLKGKSRSSKRFEKSKESDSDRGVTEEDVKSGNENLIGLLASDDVSMTEHGQSIDNTLESTPLPTTIPTTIVNDSVDQHSTLENIPTSATSKDQIETIITKPTANIMNDQTDSDPLPKVDNKPISNNEEGPKSLKEGNSEQNPSENISPEDVTLTKTDNSENKESSLRSNSNISFHISNVWLEMRYTQLQILLYRPSALIPKPPIESLTVLGEFCLAAWRHTYTLYKEKLLPLNWITLFRTLTICNTILYCLCQWSIDLVASTIEIQQCVEILQHFGEKWVFAMKCADVFQNISNTIVEISLSQGQDPNIDKLTRELFGASNAYLEILNENNVDVSWEDRFR
The following text describes a protein:
Function:
Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.
Subcellular Localization:
Cytoplasm.
Sequence:
MDMREVVVIGAGISGLSTAYRLKKEGVDVVVYEKDDRIGGTIHTVKEKGYLFEVGAQTILADQEVIDFLKEAGIEPVEASPSSKYRYIYKKGRLIPLPMSPVEFLKTPLLSLKTKLKVLTEIFKRGVDEDISIADFVREHFGEEFLNYVVAPFISGVYAGDPEKLSLKHATPKLYEAQKKYGSLIKAFIKEKTAGPKGKLISFGEGLGELINALAQKLEVHTENVVLRMRKFEDFFRLDVRGKKVETKSVVVASPAYTSSYLLKEVSFSASEEFDKIDYPPVVVVNVGVEGKFPKVRLLSSESGKKRILGAMFMSKLFPGRAPQGKELLTVFLGGATDREVIELSEEEIENIVERELKEILQIDCIDFMHVQKWKRAIPQYTLGYDRFLNLAQEMEKDYPGLFLTGNWLYGVSTADCIRASKKVAQKVLSFLRPQA
The following text describes a protein:
Function:
NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MRPAGTLASFLERCSARKRGRGCVVLTGAGCSTESGIPDYRGPNGQYHRADFVLLTFQKFMRDDNEKRRYWARSMLGYSTMCGASCNAAHMALQAFTKSGAVAHILTQNVDGLHHLATYGGVGDAEEEHYYKYTTSDAPLKELHGNIHNVICTSCGFFMPRARLQRELRERNPGFYEQYGADVSRTRPDGDYSAPTEAVNAMHLVMCPRCNGFFKPHVVLFGENVPKPIVEATMSLVRDKASCLLCLGTSLQVYSAYRYVLQANQLGIPVAIVNAGTTRGDAIADLKLDVESVGSVLAETAHEMLGVPASMFFRRKTIQL
The following text describes a protein:
Function:
Common component of the spliceosome and rRNA processing machinery; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MGSDSETERSAQKQREKKKLAALAPIAKPLAGKKLCKRTLKLVRLAAEHKCLKRGVKEVVKSIRRGNKGICVIAGNISPIDVITHVPILCEEVNIPYVYVPSKEDLANAGATKRPTCCVLVLTKPAKGELGQEEQEKLKGEHDLVATEITELANSMF
The following text describes a protein:
Function:
Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side.
Sequence:
MLRSPWTMLCGVGPPGLAPKRKPKIRIESGYERENQKYYEERGHFFSAFASISILSLGCTFLFVPLYRMYCAPTGRGADPKFYTPQAQRDREQLNEMYPVPKKLLKVRFLSDVGNTMPIAFVPLQKEVEVLIGEPALAFYSAYNRSNRTLLGVSSYTIAPPEATNYLNKIQCFCFEEQRFKPHELVEMPVFFYIDRDFLNDPMVNWLDEVIVNYTFFNLEKTKDIIFRSNLA
The following text describes a protein:
Function:
Responsible for supersensitivity to the spindle poison, isopropyl N-3-chlorophenyl carbamate. Has a role in meiosis.
Subcellular Localization:
Cytoplasm.
Sequence:
MTKKNAFKNSEDMKKYHLSEFNSEATSLTRPSPKSLQHVPCKFFRQGTCTSGKNCIFSHDLELATEKTICKYFQKGNCKFGSKCALEHVLPDGRKVKTRAFAPSTTAMGSSSQNISAAPMANIISNNDKILPMTTMASATASEEKNRIKDEALVIKKEESNVAIPSEVTVAANAFSASTEDVYSIVGDSLSKKASVKDFSDVTGIETIPAYVEATNGSSTVRSPHAKRSLSSISVKSSTSPFSGSKFLSSSSYPHTPEAHLNSNHISPASFGSGIRTRNIFNPESMSLGLKPPILNRSYSASMAPGFSMNTFTATGNLGRPTKSPSVPTSVGSNKSRKFPGINGSTLTATPSSLENLYPLSSRRSVPNLISSLGTSPSTFSSQFLKSTDRTHSFTSKLQSFNPVGTSLLASSLGTSQEDSVNYDIPDEFANEEDFIPNSLQELLTPEELERKMSHGDEAVSSSSASRFMSKVSSNLNSGNPTPYNSYNGTPTSSRFVAFFDRHRQESEKATPPSLNKVSQEPLTATTPKNLGNLTAISETLENGQTLKSNMASSIEKSKTSTEVVASYDTTLDEETQFQMDEA
The following text describes a protein:
Function:
Catalyzes the dephosphorylation of 2-phosphoglycolate.
Sequence:
MDTADPPLAVDIDGTLSRADRSIDGRVLDVLRGWDGPVVVATGKALPYAVALCQFAGIDERVIAENGGVAYVGDELLHFGDSRAVEQVAAAFEDAGHDIGWGDADLTNRWRETELAVSREQPLDVLSALAADHGLHVVDTGFAYHVKPESMSKGNALPAVAARLGVTAGDFVAVGDSANDVELFEAVGESYAVGNADDHAKGAAETVLSETHGDGFLAAVDRIRS
The following text describes a protein:
Function:
Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
Sequence:
MDVEASAEQPLLRGDEARKRPNSLRCGVVAWAVFAAVLVFLIVMTATFAGRGGGSSGSSSSGKPTFAVPPGAIVGCTDSELLCLIARPVPGPDADYRGHPRKVRGSKGLVATDQSRCADIGAEVLQEGGHAVDAAVAAALCQGVVNPFASGAGGGFFALLRDGASGAAEFVNAREVAPAAAYADMYSGKPAGASLEGGLAVAVPMELKGLEAMWRRHGRLPWRRLVAPAAAIARHGFAAHPYYTYSASGPGNLKKLRASALAREAFLVLDAAAAANASALASGEAWRAPEVGELCCARPRLADTLEAVGRYGVSWLYSPARAEVLAAEVRAAGGIMTAADILAAEPRIQPPLSYTLPGPVPYTLLVPPPPSSGPVLYLALSVLLGYLNSSSNGAATANATAAATAAWAAAMGGLPELATHRTVEAMKHAFAVRMALGDPGPDPAAPPPPGSPYVDVREVMADIADPAFAAELRAAINDSSVLDLANYGGRWNPKRTGVSPDDHGTSHLSVLDGEGNAVSLTTTVNTGFGSGLVSRSTGLLLNNEMDDFSQPGAPNKYNLEPAVANYIAPGKQPLSSMAPALLLAPPPAAAATATAAAAAAATAGGGQQQQQQQQLRLVVGASNGPRIITGILQTVIRLLYGGSDLLAAVSDSRLHSQWLPDSVLFENYTLNGVDFSQPPGLVAALEARGDTLEPFYDQLGDVQAILLDEQQPPAGGGGGGGGVAATAVSDPRKDGAPAAAG
The following text describes a protein:
Function:
Probable transcription factor that may function in the maintenance of the proper function of the central cell in pollen tube attraction.
Subcellular Localization:
Nucleus.
Sequence:
MKQSSFSSSSSSRNSTSLTNRLKTIFKKAEELSILCAIDVCVIYYGPDGELRTWPKERNTVKDMASRYKEATKRKKKRTLSTLQERLRIVESQKQQNKNLVHQSLTPSYLNQIQHLNPSNFSPYMYNHGDAATLSQLPLSASLSNQLQLPESLDAAWFWSEHVFGQHHQQQQLSTSWRVKHTRILTVSFGTSICSE
The following text describes a protein:
Function:
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MAQRRTGSSQPSESTSWSPPNNVSSQHASVTPKRLAPAPMQLVTLSLVMRILSVTLLIATSHLQQAFDTSHELLSYTLDPHTSHSLSAGSFNWTLAFVRWDTIYFLASASPYHASSTGSVHQGGYAWEQTLAFQPGIIGLLRLTGYLTPTMDGSWSPTAAILVTMLLANVAAAASVVLLYRLSLRVTRNAELAYTAALLSIVAPSAGTTLASPTPESFYSLASLVGLLYLETNSIHGCGWGTVAITSFWFAVATAFRANGALLVGYVAFKLIGEARCGRVISAALKLAASTAVCMSANVLFQVWAYGRFCLDEQTKRPWCARCVPSVYTFVQSQYWDVGLFRYWHASQLPNFALGAPVLALIAYTAYTFYCRSSWSKLARSLIGSACNGDAGKTTRDTGLMLATTPRAVPYIVHGGVLGAMLLFASHVQIALRLATPGGMPMLWWGAAHAVLYCKRSWLSRALVGYLCVQYCVGIVLYAGFYPPA
The following text describes a protein:
Function:
The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel (By similarity). Plays an important role in excitation-contraction coupling (By similarity).
Miscellaneous:
MISCELLANEOUS: Binds gabapentin, an antiepileptic drug.
Subcellular Localization:
Membrane; Single-pass type I membrane protein. Cell membrane.
Domain:
The MIDAS-like motif in the VWFA domain binds divalent metal cations and is required to promote trafficking of the alpha-1 (CACNA1) subunit to the plasma membrane by an integrin-like switch.
Sequence:
MAAGCLLALTLTLFQSWLIGPSSEEPFPSPVTIKSWVDKMQEDLVTLAKTASGVTQLADIYEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLAMEAEKVQAAHQWREDFASNEVVYYNAKDDLDPERNESESGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVLNELNWTSALDEVFKRNRDEDPTLLWQVFAADRLARYYPASPWVDNSRTPNKIDLYDVRRRPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQDVSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFTFAFEQLLNYNVSRANCNKIIMLFTDGGEERAQEIFAKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIRINTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNVTGQSENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKNPKSQEPVTLDFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYRYLALVLPTYSFYYIKAKIEETITQARSKKGKMKDSETLKPDNFEESGYTFIAPREYCNDLKPSDNNTEFLLNFNEFIDRKTPNNPSCNTDLINRILLDAGFTNELVQNYWSKQKNIKGVKARFVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGIMVSKAVELYIQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVILDDGGFLLMANHDDYTNQIGRFFGEIDPRMMRHLVNISLYAFNKSYDYQSVCDPGAAPKQGAGHRSAYVPSITDILQIGWWATAAAWSILQQLLLSLTFPRLLEAVEMEEDDFTASLSKQSCITEQTQYFFKNDTKSFSGLLDCGNCSRIFHVEKLMNTNLVFIMVESKGTCPCDTRLLMQAEQTSDGPDPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWSIFGLQFILLWLVSGSRHYLW
The following text describes a protein:
Function:
May be involved in plant defense signaling.
Subcellular Localization:
Cell membrane.
Sequence:
MHFPLVSAWNKRRRSKSYDTDPCTFLFSIIFARWHKRVYRTAECWQIEDQASQPRKRRFGSSVYTLKEMEEATSSFSDENLLGKGGFGRVYQGTLKTGEVVAIKKMDLPTFKKADGEREFRVEVDILSRLDHPNLVSLIGYCADGKHRFLVYEYMQNGNLQDHLNGIKEAKISWPIRLRIALGAAKGLAYLHSSSSVGIPIVHRDFKSTNVLLDSNYNAKISDFGLAKLMPEGKDTCVTARVLGTFGYFDPEYTSTGKLTLQSDIYAFGVVLLELLTGRRAVDLTQGPNEQNLVLQVRNILNDRKKLRKVIDVELPRNSYSMEAITMFADLASRCIRIESKERPSVMDCVKELQLIIYTNSKGGLGGTIPTFRRL
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.
Subcellular Localization:
Secreted.
Sequence:
MATNLAALVVLAAFLAGPAACEGASICFNGWLRLPTYNPWLCSRGSRTRGLPWQRGRSPSGLGLGHGYYDNRWSRSYCPRAEVIVRGAVRDAVAAYPGIGAGLIRLFFHDCFVRGCDASVLLTTTNSNNSDTEREGLPNKNSLRGFEVIDAAKAAIEAACPGKVSCADIVAFAARDASYFLSNRRINIRMPGGRYDGRESFANETDQLPGPFSNVAELQASFAAKGLTSDEMVTLSGAHTIGGARCMFFSSRFSEMDPAFAAKLRTQCNGNDDTNVNQDDVTPYVLDKQYYRNVIDRKVLFTSDAVLNSTDTMTQVRENANRAGAWERKFERAMENMGKIGIKTRADQGAEIRKVCSRVNN
The following text describes a protein:
Function:
Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MAPHLKVTLYEGSERLGGWLRTKRIDVGDGEVVFEQGPRTLRPNTPAGFVTLNLIRDLGLTEQVIKTDKTSAAALNRFIYYPDRLVCMPEPSQGTYAIAWKLLTEPVFKGFYKMLFEYKRPRRPRELDDESVGSFLARRTGTTDIPNNLVSAVFHGIYAGDIYKLSAKSITSAQWGMEGAYGSITAGISQMGKFQNAIPEDVDMENEEKSLFTDNERAIVEGTSVYTFRRGIGTLSEALESSLRSNPNVEIKLGENVGKIEYDDQKEGIKVYTTQTGEPPTFHSYVISTLSGRTLSTLTTASDDSFLTSLAETEAVTVMVVNLYYRDEDLLPERGFGYLIPRSIPYDQNPEFALGVVFDSDATVGQDTVPGTKVTVMLGGHWWDDFETYPDEEEGISMAKAVLQRHLKIDQDPEMAHASLQKDCIPQYTVGHEKRLKQAHYELLSAYKGRLAVAGNSYTGVGVNDCIKAAKVVASDVARVFAITGKRVSARPDLLHSSAFYTDTANEKLPSFAFDHEDSISTRFVFERSYGNEMMQKGFHLRHLNKRSLFSTDRRLRILR
The following text describes a protein:
Function:
Cofactor for serine ADP-ribosylation that confers serine specificity on PARP. Switches the amino acid specificity of PARP from aspartate or glutamate to serine residues. Acts by completing the active site of PARP: forms a composite active site composed of residues from HPF1 and PARP.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MAEVSSKRRKRTKTDIGCQSSAIKKIKEMFDAVMPEDFYDFWAFCEELNPKNPEDALMDTMGLQLVGPYDVLTGKLDGLSESSYHLHWRYYYDPPEFMTVIRGNEDQGFHIGYYRDEPQALPVFVASNKAKVSCEMSVIGENLFSALNTCITENLKKIKDKSQQSSLKKMQTSLITKAKELQYSLATTTPAIKARNKKVNSKTLHKAGIVVPVNAMDVGYRPLTVTDAELKKMLKTITESENKSAKDKASDELQELLTFVQFANDEGDYGMGLELGLDLFCFGSKQFHNTILQLLPLAYQLLGREKYAKIIQEHLENRDREKLSEAS