lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins.
Sequence:
MIVKLRISEHVKKRICDPTFASSPGTGELYGTICDGVPTVIGFARVLKQLAEAATVDPDAAEKCAPADTPAPIQHSLPSGLDLIGWVKTGPYADPTDFLLKAGPDAFVTDNPVYLHYTGEPGADLQTFIFEQRKLQSVECVLFADEFLHREYYLLRLQCTLTLVCEQTEKSVCENAFRLRRQLGSGSVAFTVPAAAGVMLSDYAVTGIDKEESVEMLHAMVTAPKPEQDDGFGVAGGRVKAKKVPVSNKAPSGYRVIDFGLLIKKSKDEVDEKLRREACNVTIDRRNEAQTVKVPFQVDCLSMVHRTKKLDKCFDNMVESVDCSLGLIEAALLEQLRHQKRLYVSKCYHMLPRELGHFVTCVYPLGEEVSETDSFLERQRASMHKQFVLPLNRPYFRKGNAHRFGPSKVLINPHETLTVPHPEGRTAVVDGVYTYHHYMQDSFDDNGWGCAYRSLQTLVSWFNLQGYSSGPIPTHNDIQSCLVRLGDKQRPFIGSRQWIGSTEVSMCLSGLLGIDSRIMFVMHGSELASRGMELLQHFQQEGTPIMIGGGVLAHTILGVSMNAELGETKFLILDPHYTGPDELGPVLGKGWCAWKGGDFWDKVAHYNLCMPIRPKRL
The following text describes a protein:
Function:
Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Has no protein kinase activity in vitro.
Subcellular Localization:
Chromosome, centromere, kinetochore. Cytoplasm. Midbody.
Sequence:
MSHSIRLLQPCPVRIGSIKYDSDEKQLHEDVKYGCYTKVKQMLKKGISADSINSLGQTPLFIAALLGHSKMVDLLLRYGSNPNHRCFDWSTPVHAAAFSGNQWILSMLIDAGGDLRLHDQDCRKPYCWALLAGRHNNAQMIEFIDRCTAHMQALVQCFPYKALKKVDSSSILIHNSSLMDLLSQGNAEKYGGVSTKTISSFGYGKLYFTDDSYLSCMAYIPYVEERDLVQGNDKPVFSFSAGQYMTMTNLMWGYSEVTVKELMLPTRQTCNKSYFSDLLFAEQEYLSKLHHPHILQLLAVCVSPDLEKTRLVFERVISGTLYSILHERRTDFPILDMETILNIFLQVIDALIFVHWRGFIHCAFSSHAINIILPGLAKLSNFEYMAESKDGKVHTDVSHFPVPPYLYRWSAPEVIMGKTISTKSDLFSFCVVMQEVLTDTLPWDGLDGLTVKNAVVSGQNLAVDLRIAKPYDKIVSTGIQAMAKDRAISLQDIRWMLKKDIEDFLESRKSTSETLGTECQNLYPNVNNLFQPRRSLSKEPHKLQTDTLDHKKTFGDEETEIHCNCRPIVTWHLDSENPNKQTLHTEADQSVLVSDFAQDDQNKDTISCVQVNAFSKRTDVDYQLENQKTKPQMGKNTYNLESHAEEKHVVYHQVITENSSSETDSESNTEEIYSLCEIVDPVKDTQIGETVRSNRASSLQKHISSITDKLAISNLLEKLNEALNSVENALKKSDNTHMQTYKKQKAEECVTCKISDEISRDEVDDMCGALKMKSNAVWSAVEPPSQYKPPRLSHMYTQSDKKNVQSEYAMGARLKTVKNELSCKDYCSPQTTCDGGQDTRKKTHRMYAEDNLKFSNIEVNKKRSKKYREILFGAKANVLQGRTENVGRTTGMASSEWSSARDHSTEPCTLRNVIPEHTTASDILRTDLRVGLDKSLNCTEDEFFTAKFELSCCSNDQYPELESVREEINVTQSTSNLIMCPSGRYKQAELGSDQLEMATVGVNKLSFIHHTSSFVDIQELSTINLPTPRAGKISTRISTPIAAVLDSSVLDTAENNTTRNNYKRIYLENKGINKGTTSSNNDTDRAHGTLDDALERIMHSEAMDTEVTDRAHSTLDEALERIMHSQAKETEVTDRMSSLDKDGP
The following text describes a protein:
Function:
Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MATRTQVKQATFLANLQYVLGQNIRQYGMFIALFVIMIIFSITTNGIFISSRNLSNLINQTGYIAVLAVGMTLVIVIRHIDLSVGFLAGFLGAVAAIALRFWELPTIVVVPMVLVMGALAGLLTALPVAELKIPSFVASLAGWLIYRGALQLVTAGTGTIIIEDETFNAIGNGFIPDVPFSLIPGYHTLTLLLGVVAIVAYVLSEIRTRNKKLAYNFEVLPLDMFVLKLVFISTLIGLLAWIMAGYNGLSWTMVIVLLVVAIYHFVTTQTVLGRHIYAVGGNPEAAELSGISVKRITYIVFASMGMLAALSGVLFASRLRSATTTAGTLFELDAIAAAYIGGVSAAGGVGNVIGSIIGALVYVSLTSGMNLMGIDIAYQYIVRGLVLVAAVIFDVTTRRRGRSA
The following text describes a protein:
Function:
CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
Sequence:
MDILLSDPNGRVYKYDILLSLHLNRLLFVGFFFLRKLRNRKREEEKRREEKMRAGLDRDYIVGDEIGRGKFGIVYLCKSITTGESYAVKSIDKTSIVDQIDLDAMEKESKLMQLVSGHSSIVGFHAVYEDAISIHLVLELCAKSDDLYSRITGNDGPMSEYHAAQVMRPLMDAIAHCHSRGVAHRDIKPDNILFSSSDNDDDRRLKVEDFGSAGFFGEGRGMEGLVGTPYYVAPEVVAGRVYGEKVDVWSAGVILYIMLAGIPPFGGESAVQVFEQVLRGSLRFPPSLFRNISSNAKDLLRRMIHRDVSRRFSADQVLRHPWMTSSGNAVTLPANGAMPAEQS
The following text describes a protein:
Function:
Proton-coupled high-affinity transporter for external inorganic phosphate. Acts as a transceptor, a membrane protein that in addition to its transporter activity also possesses receptor-like signaling activity; mediates activation of the protein kinase A (PKA) pathway targets during growth induction, triggered by phosphate addition to cells growth-arrested due to previous phosphate starvation. Is not an essential protein, since constitutive, low affinity phosphate transporters exist in yeast. Can function as a low affinity metal transporter that transports manganese, zinc, cobalt and copper. Plays a role in manganese homeostasis predominantly under manganese surplus conditions.
Miscellaneous:
MISCELLANEOUS: Present with 335000 molecules/cell in log phase SD medium.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Vacuole. Note=Accumulates at the plasma membrane in cells starved for phosphate. At high external phosphate concentrations, removed from the cell membrane via endocytosis and internalized in PKA/TPK3-dependent manner.
Sequence:
MSSVNKDTIHVAERSLHKEHLTEGGNMAFHNHLNDFAHIEDPLERRRLALESIDDEGFGWQQVKTISIAGVGFLTDSYDIFAINLGITMMSYVYWHGSMPGPSQTLLKVSTSVGTVIGQFGFGTLADIVGRKRIYGMELIIMIVCTILQTTVAHSPAINFVAVLTFYRIVMGIGIGGDYPLSSIITSEFATTKWRGAIMGAVFANQAWGQISGGIIALILVAAYKGELEYANSGAECDARCQKACDQMWRILIGLGTVLGLACLYFRLTIPESPRYQLDVNAKLELAAAAQEQDGEKKIHDTSDEDMAINGLERASTAVESLDNHPPKASFKDFCRHFGQWKYGKILLGTAGSWFTLDVAFYGLSLNSAVILQTIGYAGSKNVYKKLYDTAVGNLILICAGSLPGYWVSVFTVDIIGRKPIQLAGFIILTALFCVIGFAYHKLGDHGLLALYVICQFFQNFGPNTTTFIVPGECFPTRYRSTAHGISAASGKVGAIIAQTALGTLIDHNCARDGKPTNCWLPHVMEIFALFMLLGIFTTLLIPETKRKTLEEINELYHDEIDPATLNFRNKNNDIESSSPSQLQHEA
The following text describes a protein:
Function:
Required for seed coat mucilage deposition.
Miscellaneous:
MISCELLANEOUS: 'Roh' means corner in Czech.
Subcellular Localization:
Membrane; Single-pass membrane protein. Cytoplasm, cytosol.
Sequence:
MRPAQDNQGSFLGRISIRRNQFVDVNNEQEQEDLELFQKHIADRFTELLSPPQPPPSDEINTVASVAATEQIMSVTWLRKLMDVFLCCEAEFKAILLMGRDPTQISKPPFDRLVPEMLDRSIKALDICTAVVNGIDSVRHYQRLAEIAVTALEQRPLGDGNVRRAKRALANLVVALSLEDKENVSGGGGGGGGGNKTTERSWSFGRRSGGSSAASKGGATIGQLKSSSWAVGRNWSAAKQIHAMTANLTPPRGNEAAGLPQPMFIMSTVMVFVMWVLTAAVPCQERSGLANHLPVPPKHLNWAQSLIGIHEKIGDEWKKKEKKGSAGLMEEMTRMEKLGHSLMEFADGFHYPAEKDAAESAAVQVAEMAEICRRMEEELVPLQQQIREVFHRIVRSRAEILEVLEQAGKVSAPVV
The following text describes a protein:
Function:
Catalytic subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC.
Subcellular Localization:
Nucleus.
Sequence:
MEGAAQKEECSSDGGVFQQEDRKDLNSADTERHTEGDGNGVACISSGICGKGEGARSDQQSPRKRKREPEDEPLAKKLHSDQGHSEKVAIHYNTLQEVGLAARSQSRIFYLRNFNNWLKSVLIGDILEKVRQSRRDLTVLDLGCGKGGDLLKWRKGRISRLVCADIASVSVDQCQQRYEDMKSRNRPNDHIFNAEFITADCSKEVLAEKLKDPEMTFDVCSCQFVYHYSFETREQADMMLRNACERLRPGGYFIGTTPNAFELVKRLETSETNSFGNDVYRVTFQKKGEYPLFGCQYDFNLEGVVNVPEFLVYFPLFEEMAKKYNMRLVFKKTFCEFFAEKIQNEEHRLLMKRMQALEQYPADGRNKLVSDTPGDYEHAEGKAKSPDVKIPLGTLSKSEWDATSIYLVFVFEKTS
The following text describes a protein:
Function:
Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase. DsbE is maintained in a reduced state by DsbD.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Sequence:
MKRKVLLIPLIIFLAIAAALLWQLARNAEGDDPTNLESALIGKPVPKFRLESLDNPGQFYQADVLTQGKPVLLNVWATWCPTCRAEHQYLNQLSAQGIRVVGMNYKDDRQKAISWLKELGNPYALSLFDGDGMLGLDLGVYGAPETFLIDGNGIIRYRHAGDLNPRVWEEEIKPLWEKYSKEAAQ
The following text describes a protein:
Function:
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
Miscellaneous:
MISCELLANEOUS: Was identified as a high-confidence drug target.
Sequence:
MVHHGQMHAQPGVGLRPDTPVASGQLPSTSIRSRRSGISKAQRETWERLWPELGLLALPQSPRGTPVDTRAWFGRDAPVVLEIGSGSGTSTLAMAKAEPHVDVIAVDVYRRGLAQLLCAIDKVGSDGINIRLILGNAVDVLQHLIAPDSLCGVRVFFPDPWPKARHHKRRLLQPATMALIADRLVPSGVLHAATDHPGYAEHIAAAGDAEPRLVRVDPDTELLPISVVRPATKYERKAQLGGGAVIELLWKKHGCSERDLKIR
The following text describes a protein:
Function:
Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.
Subcellular Localization:
Cytoplasm.
Sequence:
MADKVLKEKRKQFIRSVGEGTINGLLGELLETRVLSQEEIEIVKCENATVMDKARALLDSVIRKGAPACQICITYICEEDSHLAGTLGLSAGPTSGNHLTTQDSQIVLPS
The following text describes a protein:
Function:
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Sequence:
MNFPLNSKPFLIDSPCLLLAAIFLLSFLYLTKLRTFFLRIFDLGFLLMAEPSPIIETLDESPSDDECQTMPDSSSNEIGSRNRPPRRCMRYFDYSSDDDDDLSNGIFRNRSAVYGDLYNRRPRRYMQSFDYSSDDDVEMELPKPIDIFSCSSPENKPTGVGAGLNNSGNTCFIASVLQCLTHTVPLLHSLRSYKYHCPCNCGNESFCVLRTLRYHIEHALRSSGCDIMIDRFRDNLNYFSSDFQINHQEDAHEFLQSFLDKLEKCCLDRSHRDNPPSVSSQDVNIVDHVFGGRLVSKLRCCNCNSVSETFETSPGWSLEIEDVEDLSSALESFTCVEKLEDQFTCDDCKEKVSKEKQLKFDKLPLVATFHLKRFKNNGVYMQKINKNVKFPLELDLLPYMSSNENPEVSTKYHLYAMMEHLGSGTYFGHYSAYVRSAPETWHHFDDEKVRRISEECVLSKSAYMLFYAREGTPCFASAFEELKTLFDATPMNFSPKSVLETTTITCSEECVSDLSYQTVSDSSNACNGSVGVSIPCGNSSDYHCDEAQDEVFHSAESNSGDEYFAFESTKADDSEKPFAATFHQEERPLYPDGNRATTDDAYVPVLKIQEQVSSPKREAAERAIIGEETFLTKRKMQKRNPFSKRQGKTFQIRREHLQNKKKREETCITNPFRSIVAAASDPKEKKHAVSYLRSRPCSSRSRLLVAALGVNVKKKKVSNIRRSSLHRNL
The following text describes a protein:
Function:
May down-regulate transcription mediated by NF-kappa-B and the serum response element.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MTRWARVTTTNNKRPLRATSWEDMKKGAFEGKSQNLPKSKQLEGHRLSLKSDAPQAKHKKNKKKKEYLNEDVNGFMEYLRQNSQVVHNGEVIAADSQEVREEIAVALKKDSRREGRRLKRQAAKKNAMVCFHCRKPGHGVADCPAALENHDMGTGICYRCGSTEHEITKCKAKVDPALGEFPFAKCFVCGEMGHLSRSCPDNPKGLYADGGCCRLCGSVAHFQKDCPESQNSDRTVTVGRWAKGMSADYEEILDVPKPQKPKTKIPK
The following text describes a protein:
Function:
ATP-dependent protease that regulates sporulation. Is able to bind and hydrolyze ATP. This ATP-dependent protease activity is necessary for efficient sporulation of B.subtilis. In vitro, can hydrolyze alpha-casein, an exogenous substrate of Lon proteases, in an ATP-dependent manner. PrkA also modulates sporulation by negatively regulating the transcriptional regulator Hpr/ScoC to induce the expression of sigK. The control of sporulation mediated via the Hpr/ScoC regulator is probably indirect. PrkA was originally thought to be a protein kinase, as it has been shown to phosphorylate in vitro an unidentified 60 kDa protein from B.subtilis crude extracts at a serine residue. However, Zhang et al. did not observe autophosphorylation or kinase activity for this protein, suggesting that it may have lost its kinase activity during evolution or may be a pseudokinase.
Subcellular Localization:
Forespore. Spore coat. Note=Localizes in the inner layer of the spore coat. Forms rings or cap-like structures around the forespore.
Sequence:
MDILKKIEKYREEEQRLKWEGTFADYLEIIKENPMVAQSAHSRVFNMIKDSGIEEIDGRKKYSFFDRELFGLEESLERLVEEYFHPAAKRLDVRKRILLLMGPVSGGKSTLVTMLKKGLEAYTLTDNGAVYAIKGCPMHEDPLHLIPHHLRDDFYREYGIRIEGSLSPLNVMRLEEEYGGRIEDVKVERIFFSEDKRTGIGTFSPSDPKSQDIADLTGSIDFSTIAEYGSESDPRAYRFDGELNKANRGMMEFQEMLKCDEKFLWHLLSLTQEGNFKAGRFALISADELIVAHTNETEYRSFISNKKNEALHSRIIVMPVPYNLKVSEEERIYEKMIAESDVADVHIAPHTLKVAAMFSILTRLKEPKRSDIDLVKKMRLYDGESVEGYNSVDVEDMKKEYNDEGMSGIDPRYVINRISSTIIRKNMESINSLDVLRSLKEGLDQHPSISSEDRERYLNFISAARKEYDDIAKKEVQKAFVYSYEESAKTLMDNYLDNVEAYCNKNKLRDPLTGEEMNPDEKLMRSIEEQIGISENAKKAFREEILIRISAYARKGKRFDYNSHERLREAIQKKLFADLKDVVKITTSTKTPDEQQLKKVNEVVARLIDEHGYNSTSANELLKYVGSLLNR
The following text describes a protein:
Function:
Catalyzes the trimethylation of calmodulin. Regulates roots development probably by modulating auxin signaling responses. May be involved in gravitropism. Involved in abscisic acid (ABA)-mediated and abiotic stress responses, including salt (NaCl), cold, drought and heat stresses.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDPTSSSSSALRWKILRQALLRRSDSQSQTETKRISRKATQGFNLIPCQVVDSSPQSDKSREASVCYTLPITGSPKLYLTQRVDNCSDLNDFEISNRYNIDNTGLVCQWPSEEVLAYFCKSQPERFRGKRVIELGSGYGLAGLVIAAATEASEVVISDGNPQVVNYIKRNIETNSMAFGGTSVKAMELHWNQHQLSELTNTFDIIVASDCTFFKEFHKDLARTIKMLLKAKKASEALFFSPKRGDSLEKFMKEIKDIGLHYILTENYDAQVWKRHETLVKGDEAWPNYDKNHCYPLLIQITNQI
The following text describes a protein:
Function:
Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region. Photoconversion of Pr to Pfr induces an array of morphogenic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses. Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reductase, rRNA, etc. It also controls the expression of its own gene(s) in a negative feedback fashion.
Sequence:
MASNSQHQQQHRRSQSAAQSSGTSNIRAHHNATESMTVSKAIAQYTVDARLHAVFEQSGESGKSFDYSQSVRTMSHSVPEQQISAYLSKIQRGGHIQPFGCTIAVDEATFRVIAYSENAGEMLGLAPQSVPNLEKQEILTIGTDVRTLFTSSSSVLLEKAFGAREITLLNPIWIHSKNTGKPFYAILHRVDVGIVIDLEPARTEDPALSIAGAVQSQKLAVRAISQLQSLPGGDIKLLCDTVVESVRQLTGYDRVMVYRFHEDEHGEVVAESKRPDLEPYFGLHYPATDIPQASRFLFKQNRVRMIVDCHATPLCVIQDEGLMQPLCLVGSTLRAPHGCHAQYMANMGSIASLALAVIINGNDEEAVGGRSTTRLWAFGLQLNMELQLASQLSEKHVLRTQTLLCDMLLRDSPAGIVTQSPSIMDLVKCDGAALYYQGKYYPLGVTPTETQIKDIVEWLLTYHGDSTGLSTDSLADAGYPKAATLGDAVCGMAVAYITKRDFLFWFRSHTAKEIKWGGAKHHPEDKDDGQRMHPRSSFKAFLEVVKSRSLPWDNAEMDAIHSLQLILRDSFRDAEASNSKAVVNAQLVDLELQGVDELSSVAREMVRLIETATAPIFAVDVHGCVNGWNAKVAELTGLSVEEAMGKSLVHDLVYKEYEEIVDNLLHHALKGEEDKNVEIKLRTFGAENRKKAVFVVVNACSSKDYTNNIVGVCFVGQDVTDQKLVMDKFIHIQGDYKAIVHSPNPLIPPIFASDENTCCSEWNTAMEKLTGWSRGDIIGKMLVGEVFGSCCRLKGPDALTKFMIALHNAFGGQDTEKFPFPLFDRNGKYVQALLTANKRVNMEGQIVGAFCFLQIASPELQQALTVQRQQEKKCFARLKELAYICQEIKNPLSGVSFTNSLLEATDLTEDQKQLLETSAACEKQMLKIIKDVDLESIEDGSLEFEKAEFLLGSVINAVVSQVMMLLRERNLQLIRDIPEEIKTLAVYGDQARIQQVLADFLLNMVRYSPSAEGWVEIHVRPTLKQSSEGQTIVHNEFRMVCPGEGLPPELVQDMFHSSRWMTQEGLGLSMCRKILKLMNGEVQYIRESERCYFLIIFELPMPRRGSKSITD
The following text describes a protein:
Function:
CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
Sequence:
MYAVDERETHRASPFYRAVVHAVDGRADGQTATGSCARKSRCHGYFLPKPPTTFPLSSHLRFTVPSVVHYHHRQAHIPVQPLLDQGLLLGTSKMVLAESIGKYRVGRTIGEGAFAKVRLAVDAETGGCVAVKVIDRSTVLRNNLMYQVKREISAMRLLNHPNIVKIHEVIATKTKICLVMEYVPGGQLSDKLVRQTSSSSNSSWLLSRCYLKRLDEREAKKYFYQLIDAVDYCHRRGVFHRDLKPENLLLDNQGNLKVSDFGLSVLRKLRDLWGWTEACFSTSVSTSCGSPCYVAPEVIQHKTYDGAAADIWSCGVILFELLAGYLPFQDCSLIHLYRRISRAQYALPQWITLPQKKIILRILDPSPITRAKVNDIFDDEWFQEGYNPSVRRTGSDDGDDCVDLDEAGTDSDGSHSTEVREAGGANPEPEQFINTFRLIATCRDLDLSGLFQEQKTKLGSPHSVQETLGIITAAARDVSLSARRMGSSMVIQVTPAHCVVEVSKSSGDLRAYKEVCQHVNMNTVCSIPF
The following text describes a protein:
Function:
Component of the 40S subunit of the ribosome. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
Subcellular Localization:
Cytoplasm.
Sequence:
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKIHRLRRECPADECGAGVFMASHFDRHYCGKCCLTYCFNKPEDK
The following text describes a protein:
Function:
Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.
Subcellular Localization:
Mitochondrion.
Sequence:
MFHFHQLLRHVSGLHHHTTTLQHALKAQQQQQRRQFGSGAREQLRRVLVVSKLTRLEFEKIREEQLSDECLEQRIRDRGTDYDALKYYHHLHKDVERQVVRSFQQHGIEVQVVNRITIHKDALQWADLIVPIGGDGTFLLAAGRASPFFLSNGKKTPVVGFNSDPRRSEGRLMLPKQYSVRVDEAVRRIIAQDFRWMHRSRIRTTLVGAATTERPSPMDLHEFHSQPVEHQEVMSTAPNGKSRILPYLALNEVFIGEMLSARVSHLHLRIDSSDVTTKTKSSGLCVSTGTGSTSWLTSMNRLSTNNVKDLLAIVRKRTGRTGSPLDTIDPESVSQEYNDNLVFAPDDPRLCYSIREQICVGVWPNPKGLESRGFAKEIFVKSRCVDASLVIDGSIAYNFNDGARALLEVYPEDSLLTIDMDD
The following text describes a protein:
Function:
Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
Subcellular Localization:
Periplasm.
Sequence:
MICGALLCANTISAAENNTRKQVYTQALHAATADIAQTAKNKNWQGYSVKMNIFIPAEISRYKPCQKALQVALPTAETQHLSRLRYEISCPDGQGWEVVATVKPDIYLPIWVAKQTLERGRKVQADDIELKKKNITGVQGGYITDPDEILGLTIKRRIRQLQAVIPSQLEQPVLVTRNQHVLMLAAQDGIEAQMLGIAQKNGRKGELIKVKNLSSGRVVTATVDGSGRVRMLGLSTP
The following text describes a protein:
Function:
Substrate adapter for ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MEEIFALIVSMILIAAVIPLFLWKRRVDSSRSREEDAAPPPQVQARENVGRGTGGGGRRMRRRPAASAGASSSSASNVQENISGSEDEEEDEAGGNQARASKKKEKKRQEREEQRQAEEAARESRSTKQDWYAEMRRKKDEEREAEERKLEEEEKAREAKEEEAAALEFDKWKGEFSVDAEGTTEEVEGGNQDLLSEFVEYIKKQKCVPLEDLAAEFHLRTQECINRIASLESIGRLSGVMDDRGKYIYISMEEMNAVADYIKRQGRVSISHLASKSNQFIDLEPKVQHDLTEEISGVVEEISVS
The following text describes a protein:
Function:
Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid. Assembled into trimeric units with the help of the chaperone shutoff protein. Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid. Might be involved, through its interaction with host dyneins, in the intracellular microtubule-dependent transport of incoming viral capsid to the nucleus.
Miscellaneous:
MISCELLANEOUS: All late proteins expressed from the major late promoter are produced by alternative splicing and alternative polyadenylation of the same gene giving rise to non-overlapping ORFs. A leader sequence is present in the N-terminus of all these mRNAs and is recognized by the viral shutoff protein to provide expression although conventional translation via ribosome scanning from the cap has been shut off in the host cell.
Subcellular Localization:
Virion. Host nucleus. Note=Forms the capsid icosahedric shell. Present in 720 copies per virion, assembled in 240 trimers.
Sequence:
MATPSMMPQWSYMHISGQDASEYLSPGLVQFARATETYFSLNNKFRNPTVAPTHDVTTDRSQRLTLRFIPVDREDTAYSYKARFTLAVGDNRVLDMASTYFDIRGVLDRGPTFKPYSGTAYNALAPKGAPNPCEWDEAATALEINLEEEDDDNEDEVDEQAEQQKTHVFGQAPYSGINITKEGIQIGVEGQTPKYADKTFQPEPQIGESQWYETEINHAAGRVLKKTTPMKPCYGSYAKPTNENGGQGILVKQQNGKLESQVEMQFFSTTEATAGNGDNLTPKVVLYSEDVDIETPDTHISYMPTIKEGNSRELMGQQSMPNRPNYIAFRDNFIGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLLLDSIGDRTRYFSMWNQAVDSYDPDVRIIENHGTEDELPNYCFPLGGVINTETLTKVKPKTGQENGWEKDATEFSDKNEIRVGNNFAMEINLNANLWRNFLYSNIALYLPDKLKYSPSNVKISDNPNTYDYMNKRVVAPGLVDCYINLGARWSLDYMDNVNPFNHHRNAGLRYRSMLLGNGRYVPFHIQVPQKFFAIKNLLLLPGSYTYEWNFRKDVNMVLQSSLGNDLRVDGASIKFDSICLYATFFPMAHNTASTLEAMLRNDTNDQSFNDYLSAANMLYPIPANATNVPISIPSRNWAAFRGWAFTRLKTKETPSLGSGYDPYYTYSGSIPYLDGTFYLNHTFKKVAITFDSSVSWPGNDRLLTPNEFEIKRSVDGEGYNVAQCNMTKDWFLVQMLANYNIGYQGFYIPESYKDRMYSFFRNFQPMSRQVVDDTKYKDYQQVGILHQHNNSGFVGYLAPTMREGQAYPANFPYPLIGKTAVDSITQKKFLCDRTLWRIPFSSNFMSMGALTDLGQNLLYANSAHALDMTFEVDPMDEPTLLYVLFEVFDVVRVHRPHRGVIETVYLRTPFSAGNATT
The following text describes a protein:
Function:
Component of the chloroacetanilide N-alkylformylase multicomponent enzyme system involved in the degradation of chloroacetanilide herbicides (N-alkoxyalkyl-N-chloroacetyl-substituted aniline derivatives). In vitro, catalyzes the transfers of electrons from ferredoxin (CndB1) to NADH. N-dealkylase utilizes NADH, but not NADPH, as the electron donor.
Sequence:
MAQYDVLIVGAGHGGAQAAVALRQNKFEGTIAIVGDEPELPYERPPLSKEYFSGEKSFDRILIRPATFWAERNVDMLLGKRVASVDPAGHSVTLTDGSTIGYGKLVWATGGAPRKLACSGHHLSGVHGVRTREDADRMLGEMERTTSVVVIGGGYIGLEAAAVLSKAGKKVTVLEALDRVLARVAGEALSRFYEAEHRAHGVDVQLGAKVDCIVGDDQDRVTGVQMHDGSVIPADMVIVGIGIIPAVEPLIAAGAAGGNGVDVDEYCRTSLPDIYAIGDCAMHANAFAEGARIRLESVQNANDQATTAAKHILGGTDAYHAVPWFWSNQYDLRLQTMGLSIGYDETIVRGDPANRSFSVVYLKNGRVLALDCVNAVKDYVQGKALVTGGVSPDKASLANPEIPLKTLLPA
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane. bL19m is essential for respiration.
Subcellular Localization:
Mitochondrion.
Sequence:
MFNAKHFFNLGLGFQWLQKRGIGSLKRPYNFPKPVPGPKHKDVLSLFEKKCRSVLDEQSERFKMFHRSQPNRVRPGAVLLVESYSKYPSKDSVNRFAGYLLRIRHRGPKSSILLRNVVMGVGVEYLLPIYSPQIKRIVVLKENGLSKRPRRAYLSYLRQPRFRLPPVESLVRKYIEQNQHKP
The following text describes a protein:
Function:
Plays a role in the inhibition of host NF-kappa-B. This inhibition affects both the canonical and the non-canonical pathways. Blocks the induction of host IKK phosphorylation. May also influence the normal phosphorylation state of several tegument proteins including pp28 in virions. Also suppresses virus-induced ISGylation independent of its own ISGylation.
Subcellular Localization:
Virion tegument. Host nucleus. Note=Also found in dense bodies.
Sequence:
MYAVFGLTRSEVTPHEAAAARYKHRGVIDRRGAAMTSRRAPDGGLNLDDFMRRQRGRHLDLPYPRGYTLFVCDVEETILTPRDVEYWKLLVVTQGQLRVIGTIGLANLFSWDRSVAGVAADGSVLCYEISRENFVVRAADSLPQLLERGLLHSYFEDVERAAQGRLRHGNRSGLRRDADGQVIRESACYVSRALLRHRVTPGKQEITDAMFEAGNVPSALLP