lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDALEKSLCDFTGSTPLDQRFRSLFTIKGLAATSDQHMQRAISIISQAFSDDSALLKHELAYVLGQLEDARALPTLKKILQDLSQDAMVRHEAAEAMGAISDPSVLPILEQYRSDSDVSVRETCELAISKISFDNSEEGQALKQSKAQAKLAEEQSGLGGVESAFKPIDPAPAMTPAASKEAARSQADGVRYDASHVPLFQSTLLDTNLSLFERYRAMFALRNVAHGGGDGAIQAVLALARGLQDGSALFRHEICFVFGELCHPASIPSMLHVLNDTKEHEMVRHEAAEALGGIVEEGEHAANDSANDYTRVLDTLNKWAHDMDAPRVVRESCIVALDELAYNNDPTQFHRIETSTPVAA
The following text describes a protein:
Function:
Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin to form chitosan and acetate. Chitosan is required to anchor melanin to the cell wall, for maintenance of cell wall integrity, and for proper cytokinesis. Chitosan offers an advantage during infection as it is less readily detected than chitin by host immunosurveillance mechanisms.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MFPVILATLAFAPMLLGSPYSVTLGQTLARHREGSLKSLSYPPEDEPGPEPLPAWVKRYQKAKSRGLIPSIRPAVLINGVPEYPFYSDSTVSNPRKVCSWTVSKCNSRRDIVNAPRGTMGISFDDGPQPPTSELLSFLKENEQKATHFMIGSRIHQNPSLLVETVHKNHDHIAVHTWSHPYMTTMTDEQILGEIGWTMQIINDLTGLVPAFWRPPYGDIDNRVRAISRHVFGLKTVMWSVDPNDWCLSDESSPGSECTPGSGPQNINQLIHDLKHRIRHGVHGDSPNRRFPKHGIISLEHELSWRTVQSFMQSYPLAKSLGWDTRSIPDLFGLDWYQKPVSNFTHTGILPILKKKPFTANHTSNINITTPSQADLLNHRNETAPIVLPHSHELNSSLARFPIRNEGHGLQPSGIAVTLASLIFFSTGFQLIY
The following text describes a protein:
Function:
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Sequence:
MCGSYYGNYYGTPGYGFCGYGGLGYGYGGLGCGYGSCCGCGFRRLGCGYGYGSRSLCGYGYGCGSGSGYYY
The following text describes a protein:
Function:
The Set1 complex specifically methylates 'Lys-4' of histone H3.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MDRDVTLNVDELVSKFKKEGHFDRLRKQILETVNEKESGPLLDRLKKIIDEEMVKDRTLKSKDQFRAAPLIAGAVDRSSLYEDSMEHIRSNVLSDQDLREVIYNSLEQIGIEQIEHEDEEKLLNSKTMDGRK
The following text describes a protein:
Function:
Deamination of 5-methylcytosine in DNA results in T/G mismatches. If unrepaired, these mismatches can lead to C-to-T transition mutations. The very short patch (VSP) repair process in E.coli counteracts the mutagenic process by repairing the mismatches in favor of the G-containing strand. This enzyme is an endonuclease that nicks double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the thymidine residue that is mismatched to 2'-deoxyguanosine. The incision is mismatch-dependent and strand-specific.
Sequence:
MADVHDKATRSKNMRAIATRDTAIEKRLASLLTGQGLAFRVQDASLPGRPDFVVDEYRCVIFTHGCFWHHHHCYLFKVPATRTEFWLEKIGKNVERDRRDISRLQELGWRVLIVWECALRGREKLTDEALTERLEEWICGEGASAQIDTQGIHLLA
The following text describes a protein:
Function:
FMRFamides and FMRFamide-like peptides are neuropeptides. KSAYMRF-amide has an excitatory effect on dissected pharyngeal myogenic muscle system.
Subcellular Localization:
Secreted.
Sequence:
MNSRGLILTLGVVIAVAFAQQDSEVEREMMKRKSAYMRFGRSDGGNPMEMEKRKSAYMRFGKRSSGGDEQELVGGDDIDMEKRKSAYMRFGKRSGPQEDDMPMEKRKSAYMRFGKRSSDMEVIGNEGVDGDAHDLFKRKSAYMRFGKRSMGEEEDHDMMKRKSAYMRFGR
The following text describes a protein:
Function:
Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MSPAFSSWSDFFAMGGYAFFVWLAVAMTVAPLALLALHTVLQRRAILRGVAQQRAREARMRAAQAQQEAA
The following text describes a protein:
Function:
Protein-serine O-palmitoleoyltransferase that acts as a key regulator of the Wnt signaling pathway by mediating the attachment of palmitoleate, a 16-carbon monounsaturated fatty acid (C16:1(9Z)), to Wnt proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MDYYYDDYYDEYYDHPDQAAARLFHRDLSIEETIKNCVHPSLRFATQYITNFIAINLLFSVLVLIVRKLFPTAQRSLHLLSCVCGAALVYRVIDHGFYHFLQLAVSLYAVQWTLHRWLTGTGRYIKTPFIVIAYGIGNLLVSELLEPSPETWNRIRGTQMILLMKALSLAFDTDDNHSLRSQLTVLSYSGYILCPANIVLGPWISFNDYLTIWKPPAGIEPKQCRSSSGRRMLIHVFRIVTSALMAVGFLLTSNCMIDYLLAPINSWKWVRAYGRALSFRTSHYFIGYLSQCSMMAAAADWHRAEDERSIMLPVSSLYRITSPMAVEFPRSLVQVVTAWNIPMHLWLKRYIFRTTKRPFGTGTAIALTYIISSLLHGLHYRLWITLLTIGSWTFVEHEVRKKLATIYSACVLVGKCPSSCTVHQHKSNSVFCTVINMLFFALNIFNLIYLGCIFESSEGPPDEVQQDKSMFGPWTELNYASHWLLVFAYLFYFVI
The following text describes a protein:
Function:
May play a role in chaperone-mediated protein folding.
Subcellular Localization:
Cytoplasm.
Sequence:
MVSPEADRVLRYLVEVEELAEAVLSDKRQIVDLDTKRNQNREGLRALQKDPSVSEDVMVCFGNMFIKMPHLKTKEMIQKDQEHLDKEIERLRSQLKVKVNRLLEAQGKPELKGFNLNPLNQDELKALQVILKG
The following text describes a protein:
Function:
Involved in flowering time control. Binds DNA and RNA in vitro.
Subcellular Localization:
Nucleus.
Sequence:
MSGLYSPGFSPARNLSPQIRSNPTDVDSQYLAELLAEHQKLGPFMQVLPICSKLLSQEIMRVSSIVHNHGFGDFDRHRFRSPSPMSSPNPRSNRSGNGFSPWNGLHQERLGFPQGTSMDWQGAPPSPSSHVVKKILRLDVPVDSYPNFNFVGRILGPRGNSLKRVEASTGCRVFIRGKGSIKDPGKEDKLRGKPGYEHLSDPLHILIEAEFPASIIDARLRHAQEVIEELLKPVDESQDFYKRQQLRELAMLNSTLREDSPHPGSVSPFSNGGMKRAKTGQ
The following text describes a protein:
Function:
Ligand for members of the frizzled family of seven transmembrane receptors.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MYSLFGLFVVLCLSFWSPVVTIRWLGIRHTSQHTWDKKDCNRIHGFSGKQYKICRRNLPAMLYVTAAVEMTREECQHQFQNKRWNCSTIVKAPQFLPDLKRGTPEAAFVYALSAAALTYSITQACGMKRLKPCKCGTNPKFKHPDGEWGGCHDNIARGMRFSKDFTDAVEAQRMRKHKSMAVALMNLHNNGVGRKAVHSRLEFHCRCHGVSGGCTAKTCIRRLGDFRLVADLLKNRYARIVYVESKTKSKRKARVLKSKRGRRRYTSSDLVALQGSPNYCHKNRKRGTAGTHGRLCDPTKRRGEGSCAYLCCGRGHRTEEVVHEERCECKYIWCCYVKCQTCRKRVRESRCL
The following text describes a protein:
Function:
RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs (By similarity). May play roles in cilia formation and/or maintenance.
Subcellular Localization:
Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Domain:
The horseshoe-shaped TROVE domain is built with 7 helical HEAT-like repeats, and is closed by the VWFA-like domain giving rise to a ring-shaped monomer. Single-stranded RNA is bound in the positively charged central cavity (By similarity); The MIDAS-like motif in the VWFA-like domain binds divalent metal cations.
Sequence:
MEGSANQLQPLSETQVVNSEGGCVWQVTDMNRLRRFLCFGSEGGTYYIKEQKLGLENAEALIRLIEDGRGCEVIQEIKSFSQEGRTAKQEPLLFALAVCSQCADINTKQAAFKAVPEVCRIPTHLFTFIQFKKDLKESMKCGMWGRALRKAVADWYNEKGGMAVALVVTKYKQRNGWSHKDLLRLSHLKPSSEGLAIVTKYITKGWKEVHEEYKEKALSVEAEKLLKYLEAVEKVKRTKDDLEVIHLIEEHQLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSEVSLICEKLSNEKLLKKARIHPFHVLIALETYRAGHGLRGKLKWIPDKDILQALDAAFYTTFKTVEPTGKRFLLAVDVSASMNQRALGSVLNASTVAAAMCMVVTRTEKESSVVAFACDMVPFPVTTDMTLQQVLTAMNKVPAGNTDCSLPMIWAQKTDTAADVFVVFTDNETFAGQVHPAVALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLDMCGFDTAALDVIRNFTLDVI
The following text describes a protein:
Function:
3'-to-5' exoribonuclease (RNase) specifically targeting single-stranded RNAs. Triggers miRNA accumulation in RNA-induced silencing complex (RISC), composed of miRNAs and AGO proteins, by degrading uridylated cleavage fragments. Required during plant growth and development.
Subcellular Localization:
Cytoplasm.
Sequence:
MTSFDGPKFKMTDGTYVQTKSIDVGSTTDISPYLSLIREDSITNSNRAVIFDVNWETDTKPSKWSLSSVKLSTRNLCLFLKLPNPPFHDNLNDLYRFFASKFVTFVGVQIEEDLNLLRENHGVVIRNVIEVGKLAAKARGTLLLEYLGTRELAHRVLWSDLSRLDSIESKWEERGAEERLEAAAIEGWLIFNVWDQLYE
The following text describes a protein:
Function:
Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation.
Subcellular Localization:
Cell projection, cilium, flagellum membrane; Multi-pass membrane protein.
Sequence:
MWLQDRIATFFFPKGMMLTTAALMLFFLHLGIFIRDVHNFCITYHYDHMSFHYTVVLMFSQVISICWAAMGSLYAEMTENKYVCFSALTILMLNGAMFFNRLSLEFLAIEYREEHH
The following text describes a protein:
Function:
Produces ATP from ADP in the presence of a proton gradient across the membrane.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein.
Sequence:
MAEKLKVDLVTPYKKILSEEVDEITATGALGEFSVLPGHAPFLTSLKIGELTYKKSGQIVHLALNWGYFEVEDDKVTVLVETAERADEIDLERAKAALGRAEAALKKLSPEDKDYRVMEAALERALIRMQVAGKAARK
The following text describes a protein:
Function:
Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.
Subcellular Localization:
Nucleus.
Sequence:
MEKKLVTLFGAAKKAADAAAATNRSEPEVQRCADALKHLQAFPVTYDLLVSTQVGKSLRHLKKHPCEKVQNAASELLHIWKQKIVLGKETNGNKRNGSKLSVDEKFQKQTSDSNAVKSGCSTAKEKKATASIRKPSHADQAKDSMRDKIRKDLEKALSRVASEAADDEEITDRVKARDPKQVAASVERVMFEKLRPMGVAEKRKHRSIMFNMSDEKNPDLRRRVLIGEVTPERLATMTPEELASDERRQENEEIKAKFMFKCEVPEKKKGTTDQFKCSGCGKSNCSYHQMQTRSADEPMTTYVTCAECNKRWKC
The following text describes a protein:
Function:
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Sequence:
MTAQAKLARRASKAVAASKKASKEAPCLPKSTSASPGQRAQAASALLQSTDPVQVYLRTVPTPLGPFSLYVDADGAVRFCRWQGSAPGDAAALFTEAQEVCAIIQSRWYKSTPVTVAGVSADGASELPGERAVTLMRNYFNPSTAKTGRTEELERLLLQVPIIYPPTTAFMTQTWATLRHTVPSGKTISYKGLGVRVNKALNLPASAAVAPRAIGVAMGANPIPVIVPCHRVLSSTNSLCGYGLGLRFKVWLLRHEQADVAADKLRVGEEETAVSTAASRR
The following text describes a protein:
Function:
May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.
Sequence:
MSLEEIRNFLDPFPDDVALNLTLDLSSTSNRLSSSSVFVPDISTETMNRTSDIENSATSSVQPELPGHPSTLQMVTEALKARGDKHGTSVAAIKFYICRKYPAINMRRFRYLLKQALAKGISDGVLVRPRNSTVTGARGKFKLVSKNKAKAMKTKKLTVAIKPRKKKATRSSEAGNVSLEASTKRKAPATKKKVPEEALTKKKAPATKKKVPAAAVTKKTVPVETSTKRKTPATKKKVPAEAPTKRKTPTKASTKRRVSATKKVFEEALTKRKAPATKKMVPAEAPTKRKIPTEASTKRRVSTTKKVPQEALTKRKVLTTKKKDLVEASTKKKVPKEAQKDTKVEMVKGDSKPKDASSKKGQEKSFHFT
The following text describes a protein:
Function:
Dendrite-specific motor protein which, in association with the Apba1-containing complex (LIN-10-LIN-2-LIN-7 complex), transports vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MASEAVKVVVRCRPMNQRERELRCQPVVTVDCARGQCCIQNPGAADEPPKQFTFDGAYHVDHVTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGIIPRAFEHVFESVQCAENTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKGVYVKGLSMHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHIPYRDSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPKDALLREYQEEIKKLKAILTQQMSPGSLSALLSRHVPPDPVQVEEKLLPPPVIQHDMEAEKQLIREEYEERLARLKADYKAEQESRARLEEDITAMRNSYDVRLSTLEENLRKETEAVLQAGVLYKAEVMSRSEFASSSEYPPAFQYETVVKPEVFSTTDTLPSDDVSKTQVSSRFAELPKVEPSKSEISLGSSESSSLEETSVSEAFPGPEEPSNVEVSMPTEESRNRYFLDECLGQEAAGHLLGEQNYLPEEEPQEVPLQGLLGLQDPFAEVEAKLARLSSTVARTDAPQADVPKVPVQVPAPTDLLEPRDARPEAEAADDFPPRPEVDLASEVALEVVRTAEPGMWLEAQAPVALVTQPQPLPATAGVKRESVGMEVAVLTDDPLPMVDQQQVLARLQLLEQQVVGGEQAKNKDLKEKHKRRKRYADERRKQLVAALQNSDEDSGDWVLLNVYDSIQEEVRAKSKLLEKMQRKLRAAEVEIKDLQSEFQLEKIDYLATIRRQERDSMLLQQLLEQVQPLIRRDCNYSNLEKILRESCWDEDNGFWKIPHPVITKTSLPVAVSTGPQNKPARKTSAADNSEPNMEEDRYRLMLSRSNSENIASNYFRSKRASQILSTDARKSLTHHNSPPGLSCPLSNSSAIPPTQAPEMPQPRPFRLESLDIPFTKAKRKKSKSNFGSEPL
The following text describes a protein:
Function:
May play a significant role in p53/TP53-mediating signaling pathway.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Cell cycle dependent intracellular localization.
Sequence:
MSPSAKKRPKNSRVSKMQDEKLRDETEQPVSKVIERNRLRTVLKNLSLLKLLKSSNRRIQELHKLAKRCWHSLLSVPKILRISSGENSACNKTKQNNEEFQEIGCSEKELKSKKLESTGDPKKKEYKEWKSQVQSGMRNKEKTSLAAMPRKEKHIEPEVPRTSRDDSLNPGVQGRQPLTEGPRVIFIKPYRNRTPMGHMKQLDVADQWIWFEGLPTRIHLPAPRVMCRSSTLRWVKRRCTRFCSASLEMPMWHPYKVDVTWTRARGASRGWRSRHQLKGRNGWRNSRVYK
The following text describes a protein:
Function:
RNA binding protein. Can also bind in vitro to single-stranded DNA.
Sequence:
MDYDRYKLFVGGIAKETSEEALKQYFSRYGAVLEAVVAKEKVTGKPRGFGFVRFANDCDVVKALRDTHFILGKPVDVRKAIRKHELYQQPFSMQFLERKVQQMNGGLREMSSNGVTSRTKKIFVGGLSSNTTEEEFKSYFERFGRTTDVVVMHDGVTNRPRGFGFVTYDSEDSVEVVMQSNFHELSDKRVEVKRAIPKEGIQSNNGNAVNIPPSYSSFQATPYVPEQNGYGMVLQFPPPVFGYHHNVQAVQYPYGYQFTAQVANVSWNNPIMQPTGFYCAPPHPTPPPTNNLGYIQYMNGFDLSGTNISGYNPLAWPVTGDAAGALIHQFVDLKLDVHSQAHQRMNGGNMGIPLQNGTYI
The following text describes a protein:
Function:
Required for the processing and/or for the stability of the CYTB and COX1 intron-containing pre-mRNAs and of the ATP6 transcript. Could be a stem-loop RNA-binding protein that plays a role in determining RNA stability.
Miscellaneous:
MISCELLANEOUS: Present with 2060 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MIRTSSILKNCNYRYIHCIHRCLLNEANLKDRKTHNVERVSNEKTFEQALEEERKVFGELFEAGARVENMRHTNASKIIDKYYNGLQDNSEGTSVKKEKIVFNHSQRAQRKLPNKDHEFLKETAGNDYVYERAEPSAISTKTISEQTRTLLEKIFDEDNSINKSNRELLNLNLRKGSGMEALRQPVAHSNVKFSEEVMQEIGNKIRYQTTLDQVLEPHIDYLREAVKSDYDLLRYLKQSLDIYKKRNKDLELKMNAESSNIFEDIRSACINKPAELPKPLAMTLPYIIVKSLRLGDFDFPADRKYTLISYVYNECKNNMDASLYLTICNVDFYNLLVQLLWENFQEIRYLRRVVTEMSVNGVIGNIETVDILDKIVKEMRSLNEDVFLEAGEQLSADEEVSSSANKIVNVGVLWNKDTNNDLLIVENYLKSLKKNLTRDR
The following text describes a protein:
Function:
May be involved in floral abscission.
Miscellaneous:
MISCELLANEOUS: IDL5 is only partially redundant with IDA.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
MGNKRIKAMMILVVMIMMVFSWRICEADSLRRYSSSSRPQRFFKVRRPNPRNHHHQNQGFNGDDYPPESFSGFLPKTLPIPHSAPSRKHNVYGLQRTNSRSSYFWTHAHLS
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway (By similarity). Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity). In complex with ced-3, required for the ced-3-mediated cleavage and subsequent degradation of the heterochronic protein lin-28 to regulate seam cell fate patterning during larval development. Negatively regulates glutamate metabolism through the aspartate aminotransferase got-1.2. Modulation of glutamate levels most likely controls locomotory behavior, in particular backwards locomotion or 'reversals'.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Domain:
The RING-H2 zinc finger is an atypical RING finger with a His ligand in place of the fourth Cys of the classical motif.
Sequence:
MIVDLIQSARQGEWAQVRQLLLKHWLVQVPEVFEVNSDLPWDNTAANERILGSQGEILLAPLVSAFVLDVRNTKSTLEAMNGIAGVDPARRGQICGHVFKNGELTYTCLDCATDGTCVMCLQCFEVSIHKSHKYKMHSSSGSGYCDCGDADAWTEGYACANHEKKDDEEAAVLAPELKKRCEQLVEIILQFSLSMITHKDDLKLPEIFEKMKPEVTNEAQQYLTVLYNDETHTYESVIKVLELYIHCTKDQAMLVATIVDREGRSAVKLGSKADCTKAKDDVQRKTARDPTSIRRSSNHNLPLSVKVMDTTLFALQNFSISLLTWLNTQMDVFPPLREIVGEILLSSKFALKKNYTRKMKSEDQRLVAGIIRNVMVLPDDEEEELFALDGRMDVDEMDDDDIGGEALQMEIDADDEEEITAALAGVSEHQESPGPSRDSSTFTMLENILLQDTQMWKAGRSILHQMLMRTVFMIYDQKVRFAKAFMLHYNEIYEDFIKDDHEMDVSVVGLSVQFMTVPSLARKLVAEDQAFSVISKAIRDQTDKFVKYYNDGKIARFDFTSRSFPPELRRSLHITRDMAYILNAVPSESDWNRELIDGFVQGFADFLLFLQHLQGMDEVKRQAVEHQVWESEWETAFNILLRLKDAISMIIGWAETNEEVHNRLMIMCLELMNRMPPVYTKSEEDTYELTVTINGESCRISHFDVLKSSTSVHQPVVRIIAGLFSASNYTGFLLNRSNNSHTSLNQERIKELINCKDETNLYELSLRVLVLCAQSNATLWRRNGFSLINQIHNYFSPLCRNEMFDRDVLMMQVGAALTPSTKFIFHLLHRFRLFKWATSEFEQDKANEKPAKPESEDLSKTLVMIAEEFIQCLILILCERYTYGVGKTRPMDQMKREVIHILCTGSHTFSHIQQKMSHDINSKRLSLHEAVNLVADFRKPLATTAGQFHCKESSLPTYSPFFMHYSKSDQSAAEQSQARVRAKMEKSVRACAPPILPDFQTFFERIPEILTTNVLIHVVRLIIDRTARRSRFSSDRLFHKTLYLIGIALNEEEKNPSFGFTQRAEESIGLLSLLEGLVGKPESSICPILLEVTVEKYRKLIKARAGVPEAAPAPENKPAQSEEEIKAKRAARAAEMRQKAMAKMSNMQSKFMKKIEDEEKKDESQTPSEKSETVVKKDDYDNKHFFDEDVVKQVGHDFPVCIGANKWHAELVKPRTLTCILCQEDEIIAPQQGKPMVCAAFIQQSQLFTHKNKNGELMTASSGTISTRDLLTAPATLQYGVDVSTCSHSMHYECYRSLAEANRSRESLRARQVGQHSHKMVDTENGEYQCPLCKRLSNAAIPVLPAYQLTNQNGFSTVSGAGKENFDTWVARVKRNLEMPLSSESVSKKGHSRKRSHSERSLLDLEKLSKDPDTANTSAGVLQFGAMEMSSATHMPASAESQMLMTTSPSQDDVEFYNELAAMFVDQDVNNTTSPAATPETIPAIGSSSRIPESQESGKKPLSSQIQHVLYSLIRPFPALINSNRICSSSFEGFEEPIKDLGKNMMKFRKRGNELKTNFIEKHLKGYVISTVTWQSTAHVARAISSYLHYDKKPLFGALNTRQRDCLSAMARLCASLSHNMQFLLHAVSDMLRVFLCEPPRPKLAQTPGSPLLSAPSTSSFTPAPAQIPHSGTNFAFLVQLFNPAGPRKNVNLNILQIDILSLAISLMMTIGWTWNNGTQSMNSSSTHQKARLLTPDGSVDEAYVLRLSLLAHYFQIIATHSEADGNDVNMEEEQESQMEVDPVAAQTIRKLYALCHPFDGPLRRVDILWRKMEEGAQSLLRPIALLYHFITLVDPPEALKDPSINSSEPLFRYLGLPHKIEEQISGSMLEKLFTMWSSSIPSDQALRQDLVVQPVRPNLLVELPEKYSQLINQVATFKCPTIPIEESTSNVPTLCLVCGTILCSQAYCCQKIINKQSYGACRYHMSQCSGSVGMFLRVRDCSLVLMTTRKRGCFRPAPYVDEFGEVDQGFRRGNPLHLNPELYQKLKSLWLQQGITEEVVNYNEIDFRNVQYDWGHF
The following text describes a protein:
Function:
Hydrolyzes sphingomyelin in addition to phosphatidylcholine.
Sequence:
MTENWKFRRRTFLKHGAQAATLAGLSGLFPETLRRALAVEPDIRTGTIQDVQHVVILMQENRSFDHYFGHLNGVRGFNDPRALKRQDGKPVWYQNYKYEFSPYHWDTKVTSAQWVSSQNHEWSAFHAIWNQGRNDKWMAVQYPEAMGYFKRGDIPYYYALADAFTLCEAYHQSMMGPTNPNRLYHMSGRAAPSGDGKDVHIGNDMGDGTIGASGTVDWTTYPERLSAAGVDWRVYQEGGYRSSSLWYLYVDAYWKYRLQEQNNYDCNALAWFRNFKNAPRDSDLWQRAMLARGVDQLRKDVQENTLPQVSWIVAPYCYCEHPWWGPSFGEYYVTRVLEALTSNPEVWARTVFILNYDEGDGFYDHASAPVPPWKDGVGLSTVSTAGEIEVSSGLPIGLGHRVPLIAISPWSKGGKVSAEVFDHTSVLRFLERRFGVVEENISPWRRAVCGDLTSLFDFQGAGDTQVAPDLTNVPQSDARKEDAYWQQFYRPSPKYWSYEPKSLPGQEKGQRPTLAVPYQLHATLALDIAAGKLRLTLGNDGMSLPGNPQGHSAAVFQVQPREVGNPRFYTVTSYPVVQESGEELGRTLNDELDDLLDANGRYAFEVHGPNGFFREFHGNLHLAAQMARPEVSVTYQRNGNLQLNIRNLGRLPCSVTVTPNPAYTREGSRRYELEPNQAISEVWLLRSSQGWYDLSVTASNTEANYLRRLAGHVETGKPSRSDPLLDIAAT
The following text describes a protein:
Function:
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
Subcellular Localization:
Cytoplasm.
Sequence:
MSIILSNELKQSIARISDLLKAENATLVAHYYTPAEIQALADETGGFVGDSLAMAQFGVEQPATTLMVAGVRFMGESAKILSPDKRVLMPTVEATCSLDLGCPIESFSQFCDENPDRTVVVYCNTSAAVKARAEWVVTSSNAVEIIHHLDDEGKKILWAPDRYLGSYLQKTTGADMILWKGACIVHEEFKGEVLAELRKQYPHAAVLVHPESPPSVVEQATVVGSTSQLLKASQELPNDTLIVATDRGIFYKMQQLSPHKTFIEAPTAGHGATCRSCGHCPWMAMNNLQSLEQSLITGSNEIVLDSEIMAKAKVPLQRMLDFSYNRIGATA
The following text describes a protein:
Function:
Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
Sequence:
MEEISSRNVVEGTSRAPQRAMYKAMGLDDSDLSKQMIGVCHTGNEATPCNIHLPRLALKAKEGVSDTGATPREFSTIAVSDGIAMGHEGMKSSLISREVIADSIELMVRAHQYDALVGIAGCDKSLPGTMMAMARLNVPSVFVYGGTIMPGMLNGEELTVVDVYEAVGAYDAGQLSLEGLKNIENTACPNEGSCGGMFTANTMASISEAIGLALPGSASPPAEDDRREKMVYDTGVACAKALQMDIRPREVLTFEAFENAITMLNSVGGSTNGILHLLALANEVGIKLTYDDFERVRKKTPHIADMKPGGNYVMNSLDKIGGIPFVLKKLLDKGLLNENCITITGKTIKENLNAMVMPQTEQQIIRPMENPLHNVGTAVILKGSLAPDGAVIKTAGVEMTKFTGKARVFDREELAFEAVKRGDIDEGHVVVIRYEGPKGGPGMREMLATTAALVGQGLGKKVAMVTDGRFSGGTRGFMVGHVAPEAYVGGPIALVKDDDEITIDTETNIIDLHVSSEELENRRKQWSPPKPNYTSGALAKFATLVGSAAEGAITKPNL
The following text describes a protein:
Function:
tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Sequence:
MMDGKATAVDGRFLTSALNDPTKQSQIYEYVEALKGDENGWKKSIENIVTNDLRSAEECFIMLQVVEDYVKTRYAMSDESSTNIIKQFLSHLLRKNGEEDIPSFLVNKMAQIFALVFAVDFPVRWPNFIQEVFLSSGMEDTRAIQFYLKTLLAIDSEVVDRDIQRASHVFDRNAKIKDAMRDVCMIDCVRSWYHILKEISDISTQSLVLDVIAIYVDWIDIELVANEELVPLLIDRLAHSCTTQAAQGAVCGIIGKKMPSHKKIPLVLAIAKVINEHKLLEISEECGEEDELRAANLLSAIGLAVIDSYTKTDKESLSEEKQGTLTGMKMLEKEVKTMLQLLGSNNEDVSMSMMDFVKNYIGLIMQNPSQEGDRILMNIMGVVLKRYEMDEDVDMDGTGEKQSDFHEYRKELRHVMHAITLKRPDLIIVPLEVRMREMKENRVGLKKTEANLHLIYSLSELLPNGLLNARGGWLERGGRLPLEALSILSPHSSSPTLTLLYFEIVSRYEKLMCRDSAVIISLVPHFISDYGLGNNNPTVRARQRVVRSRVIYLFSRFVKSQKSLLAAAVPEVIMRVAPLVSCQDDLSSSLLSHQDHGYLLEATATLIVFSDIEASVKAQYMTELASTIGNRFKKQLEWMGDMESRGQLDGKAKHFLEESLPANVSYTIKLTKAFGLSGKEKNMKECGCAGIFIELLNLFTSSLSFSRAFLAESTRQLAGRLVLCLDDELFPSLSLLLSSLSSLASDADSMLHLLILTNNIVQKHKGGLLSSSINVSSILEASFRLATDSNPQLLNDPTGRSLMYLKRSFLTLVLSLLTTELFERVVDADIGSRLFEFARLLSIDSDATTQKTAVTVLSRMVVGRGDEVMEQVLSTLLSLPLTPHFSFKDAASQLVLHEVRSTIHACFVQRPTLVTSLISSNFPGDFCEQMLSSLTTLSGKDADRTFTMLYTQLRAS
The following text describes a protein:
Function:
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
MKGFNIPMYINKRYKHLQNSDIRTSLLKPEHLSSTPQTKCALEPVMDVYCSNNVLQARRAVEQLRMETELQRIKISAAAEQLVQYCQEHRRADPLLTGIAASSNPFKDKKTCVLL
The following text describes a protein:
Function:
Shell component of a type 1 encapsulin nanocompartment. Assembles into proteinaceous shells 23-24 nm in diameter with 2-2.5 nm thick walls. Cargo protein Flp (ferritin-like protein, probably stores iron) is targeted to the interior via its C-terminal extension; empty intact shells can be isolated in the absence of cargo protein. Fe(2+) may be able to pass though the 5-fold and dimer channels in the protein shell (Probable); Protease that exhibits activity toward chymotrypsin and trypsin substrates. Probably does not have antibacterial activity (Probable).
Miscellaneous:
MISCELLANEOUS: Shows substantial structural similarity to gp5 of the HK97 viral capsid; while the sequence homology is weak, it suggests this protein may have evolved from a viral capsid protein.
Subcellular Localization:
Encapsulin nanocompartment. Note=Globular particles 19-20 nm, with 60-80 nm long tails (Probable). Shells are 23-24 nm in diameter, walls are 2.0-2.5 nm thick.
Domain:
Has 3 domains; a discontinuous peripheral domain (P, 13-39, 76-133, 221-254), an elongated loop (E, 53-73) and the discontinuous axial domain (A, 137-216 and 259-263). The E-loop forms contacts between two subunits, while the A domain mediates contacts in the 5-fold interface. Pores are formed by residues 184-189, pore size can be modified by mutagenesis.
Sequence:
MEFLKRSFAPLTEKQWQEIDNRAREIFKTQLYGRKFVDVEGPYGWEYAAHPLGEVEVLSDENEVVKWGLRKSLPLIELRATFTLDLWELDNLERGKPNVDLSSLEETVRKVAEFEDEVIFRGCEKSGVKGLLSFEERKIECGSTPKDLLEAIVRALSIFSKDGIEGPYTLVINTDRWINFLKEEAGHYPLEKRVEECLRGGKIITTPRIEDALVVSERGGDFKLILGQDLSIGYEDREKDAVRLFITETFTFQVVNPEALILLKF
The following text describes a protein:
Function:
Required for arbuscular mycorrhiza (AM) development during AM symbiosis with AM fungi (e.g. Glomeromycota intraradices).
Subcellular Localization:
Secreted, extracellular space, apoplast.
Sequence:
MDRSSIGLLLLLVSITSFSVTCCYSASEDDLMQTYIVYTGNSIKDESSSLLLHYENLLQQVVDSNQMPKPILQHYKRSFNGFVANLTKKEADRMAGLDGVVSVFPNKKRKLLTTKSWDFIGFPQNVQRENYESDVIVGVIDSGIWPESESFNDKGFSPPPSKWKGTCQTSDVPCNNKLIGAKYYISFYDEPSSEEYLDSPRDSNGHGTHTASIADGNLVSMVSMLGLAQGTIRGGVPSARVAVYKVCWSKHCYDANILAAFDDAIADGVDILSVSLSSNENEDSIYFRDGLSIGSFHAMKHGVLTIFAAGNAGPHPSSLRNFSPWAVVVAASTLDRKFVTKIKLGDNRTYEGVSLNTFDLEGKLYPIIYGGDAPNKLAGYNRHQSRLCGTNSLDDKLVKGKIVLCEGVEGDPEALRVGAVDTLAPVVASFSSRGPSNATLEILKPDLIAPGVDIIASWPARSPISENLGENRKLEFNIMSGTSMSCPHVSGAAAYLKSFHPTWSPAALRSALMTTAKQMSPKNNHCAEFAYGAGQIDPVKAVNPGLIYETNEGDYIRLLCGQGFNETVLQLITEETISCSEIGYATARDLNYPSFALKAPHPKHYLSGSFKRTVTNVGLAMSTYRSIVTSHEGLNISVNPSVLTFTSLGEKQTFVLAVNGRMKNYLESAYLIWDDVQLSTAIIEKH