lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Promotes lateral root initiation and development, independently of auxin (IAA) and abscisis acid (ABA).
Subcellular Localization:
Nucleus.
Sequence:
MRWIEWIISHSLLRMAESNSQALNNFWLNHGAKLLLRLMESSQEDVQERAATGLATFIVVDDENASIDCGRAEAVMRDGGIKLLLKLAKSWREGLQSEAAKAIANLSVNANVAKAVAEEGGIDVLAGLAKSMNRLVAEEAAGGLWNLSVGEEHKNQIAKAGGVNALVKLIFRWPNGCDGVLERAAGALANLAADDKCSTEVARAGGVHALVMLARNCKYEGAQEQAARALANLAAHGDSNNNNAAVGQEAGALEALVQLTKSPHEGVQQEAAGALWNLSFDDKNRESIAAFGGVEALVALAKSCSDASTGLQERAAGALWGLSVSEANSIAIGQEGGIPPLIALAGSEAEDVHETAAGALWNLAFNPGNALRIVAEGGVTALVHLCSSSVSKMARFMAALALAYMFDGRMDEYAMIGTSSESASKSVSLAGARIKALKHIESFVTTFMEPQVFAAAALSSAPSMLAQVSEKVRIPEAGHLRCSGSEIGRFVTMLRNPSPILKACAAFALVQFTIPGGRHAMHHASLMQNAGEARILRSAAAAANMPREAKIFAKIVLRNLEHHHQAECSKGKKSVIL
The following text describes a protein:
Function:
Transcriptional activator that binds specific DNA sequence. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. May directly activate some type-A response regulators in response to cytokinins (By similarity). Functions as a response regulator in response to cytokinins.
Subcellular Localization:
Cytoplasm, cytosol. Nucleus.
Sequence:
MAQKEGLPAGRLSAMVIDEDKCHADSTSYMLSAELNFSVTVFTSPIKALDFLQNHAEGVDLVLADVHMEEMNGFDFLKVARELHKSIQVIMMSTETTMYTMKRCVKLGAQFLVNKPLDAGTIKNLWQYVDLKVLRMEKIKDLLQGIGDESTCANETNSLAENPKNDTKKKYYLMWTPHLQKKFLHALQILGKDASPKNIKKIMGVDNIDCRQIAAHLQKHRLRLTKDLKKASFTTDTSKDESNSRIGPAESHHVCRNASTLQPRSNTQPTETTMQILSEDAEYDDVYAAMRRALQYGIVFDESKHSSDPSGDEDEQVVVGGDQDGCANEANDIDSSGDHHQVAAVVTKPCNANASQEIINKMTNSDGMQATKGSKAAVFRLVDYSESDSD
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 2270 (Gm2270) in the 21S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. This modification seems to be important for the normal accumulation of the mitochondrial large ribosomal subunit.
Miscellaneous:
MISCELLANEOUS: Present with 2760 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MTSLTNAVFKRYLAVTPSAHQALKTRIKKKSSSFDKFFPQQSNSRKKQWETLNEDKASWFKRKYAHVHAREQDRAADPYGKKKAHVEKLKEIKNQAKLNQKSHKSKFQNKDIALKLMNDNPIFEYVYGTNSVYAALLNPSRNCHSRLLYHGTIPSKFLQIVDELKVTTELVDKHRLNLLTNYGVHNNIALETKPLQPVEIAYLGDMDTSSAALSIHELGFNNENIPHELPYGTKTDAKKFPLGLYLDEITDPHNIGAIIRSAYFLGVDFIVMSRRNCSPLTPVVSKTSSGALELLPIFYVDKPLEFFTKSQEMGGWTFITSHLANATSEKYTVGKTISMHDLNGLCNELPVVLVVGNESQGVRTNLKMRSDFFVEIPFGGIEKGNRAPEPIVDSLNVSVATALLIDNILTCK
The following text describes a protein:
Function:
M/G1-specific cyclin partner of the cyclin-dependent kinase (CDK) PHO85. May have a role in bud site selection in G1 phase.
Sequence:
MISDYDALLQFNKKPVSQEMIQFLATSTASIIKIRENNNPIQGCRPPDLSIFIKNVVIQSNVQTPTLMATSVYLNKLKSVIPKNVYGINTTRHRIFLGCLILAAKTLNDSSPWNKHWTTYTEGLLRIREVNTIERELLEYLNWDVRITTPDLIDSLSYFLGPIKEQLFLQRRQEMLLFNAPSPGQLKEYINHRRPVSHSRTSSAISVPSLTSMATVSTTDSRSSLLAKYQPSLPLVESDNFNKKNHVPLRNNNDICNNFRAEENIHSVNHIDVTMGSSPVMSHKPTIHQRLNFTRRGWSSFFKQ
The following text describes a protein:
Function:
Ubiquitin-specific protease that regulates cell survival in various contexts through modulating the protein stability of some of its substrates including DDB2, MCL1 or TP53. Plays a positive role on ferritinophagy where ferritin is degraded in lysosomes and releases free iron.
Sequence:
MESEEEQHMTTLLCMGFSDPATIRKALRLAKNDINEAVALLTNERPGLDYGGYEPMDSGGGPSPGPGGGPRGDGGGDGGGGGPSRGGSTGGGGGFDPPPAYHEVVDAEKNDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLLASTYLARLGLSESDENCRRFMDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLIELVAERIKQDPIPTGLLGVLTMAFNPDNEYHFKNRMKVSQRNWAEVFGEGNMFAVSPVSTFQKEPHGWVVDLVNKFGELGGFAAIQAKLHSEDIELGAVSALIQPLGVCAEYLNSSVVQPMLDPVILTTIQDVRSVEEKDLKDKRLVSIPELLSAVKLLCMRFQPDLVTIVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTLSKSVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWKIQSGQSSTVIENIHTIIAAAAVKFNSDQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARFETTSGKVLDVLWELAHLPTLPSSLIQQALEEHLTILSDAYAVKEAIKRSYIIKCIEDIKRPGEWSGLEKNKKDGFKSSQLNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLIACHRLAAAVAGPGGLSGSTLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFNLFKTFFENVNLCDHRLKRQGAQLYVEKLELIGMDFIWKIAMESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDFYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTVEAHSNETIGSVRWKIAKQLCSPVDNIQIFTNDSLLTVNKDQKLLHQLGFSDEQILTVKTSGSGTPSGSSADSSTSSSSSSSGVFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDSLGRKKTLLSESSSQSSKSPSLSSKQQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDDMARSCAKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTMPTLLDEDLTKDGIEALSSRPFRNVSRQTSRQMSLCGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEVSDFTSTVACFMRLSWAAAAGRLDLVGSSQPIKESNSLCPAGIRNRLSSSGSNCSSGSEGEPVALHAGICVRQQSVSTKDSLIAGEALSLLVTCLQLRSQQLASFYNLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSAHPDVQKPNQFLLGVILTAQLPLWSPTSIMRGVNQRLLSQCMEYFDLRCQLLDDLTTSEMEQLRISPATMLEDEITWLDNFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEMLGSSLIKPLLDDFLFRASRIILNSHSPAGSAAISQQDFHPKCSTANSRLAAYEVLVMLADSSPSNLQIIIKELLSMHHQPDPALTKEFDYLPPVDSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGRDQIFKNTFQGIYSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGENGRSVDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYTDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEKKGLFVEKMPARIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKLKHPYYPCMAKVSLQLAIQFLFQTYLRTKKKLRVDTEEWIATIEALLSKSFDACQWLVEYFISSEGRELIKIFLLECNVREVRVAVATILEKTLDSALFYQDKLKSLHQLLEVLLALLDKDVPENCKNCAQYFFLFNTFVQKQGIRAGDLLLRHSALRHMISFLLGASRQNNQIRRWSSAQAREFGNLHNTVALLVLHSDVSSQRNVAPGIFKQRPPISIAPSSPLLPLHEEVEALLFMSEGKPYLLEVMFALRELTGSLLALIEMVVYCCFCNEHFSFTMLHFIKNQLETAPPHELKNTFQLLHEILVIEDPIQVERVKFVFETENGLLALMHHSNHVDSSRCYQCVKFLVTLAQKCPAAKEYFKENSHHWSWAVQWLQKKMSEHYWTPQSNVSNETSTGKTFQRTISAQDTLAYATALLNEKEQSGSSNGSESSPANENGDRHLQQGSESPMMIGELRSDLDDVDP
The following text describes a protein:
Function:
Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity.
Subcellular Localization:
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Synapse, synaptosome.
Sequence:
MDIANQLVAQGQFRVLKVPLGFIKILEWVFAIFAFSTCGSYSGSFRMSVECKNRSDSNLKIDVDFEYPFRLHQVYFNAPTCKNGQSDRFFLVGDYSSSAEFFVTIAVFAFLYSMAALSIYIFAFEKYRENNKGPLIDFGVTCVFTFMWLVSSAAWAKGLSDVKTATDPEKVLDLIPACENSGNRCREVYDPVMSGLNTSVVFGFLNLILWTGNLWFVFKETGIVAPFMRQQPAQEKQPAPDSYGQAGYGQQDPYAGSQGGYQPDYSQQGYNQGGDYGQGGYEQQGAPTSFSNQM
The following text describes a protein:
Function:
The phosphorylation status of MCRIP1 functions as a molecular switch to regulate epithelial-mesenchymal transition. Unphosphorylated MCRIP1 binds to and inhibits the transcriptional corepressor CTBP(s). When phosphorylated by MAPK/ERK, MCRIP1 releases CTBP(s) resulting in transcriptional silencing of the E-cadherin gene and induction of epithelial-mesenchymal transition.
Subcellular Localization:
Nucleus. Cytoplasm, Stress granule.
Sequence:
MTSSPVSRVVYNGKRTSSPRSPPSSSEIFTPAHEENVRFIYEAWQGVERDLRGQVPGGERGLVEEYVEKVPNPSLKTFKPIDLSDLKRRSTQDAKKS
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MSPTSSHPPLLSTSHFSPPSPSLSSALHLDPPVPMRVTFADMAVYFGDVMWESYRNLISLGFPIPKPELITHLEQEAEPWGPGPQESEERDPRDPYPSVRTKEEEEAESVPDPPSALDGSAPPATACGTALPPPPASPPPPPKPFSCPECGSCFSRRSHLSRHRLIHSGERPFPCPECGKCFAQGAHLALHLRSHTGDRPYSCGQCGRSFRHGSHLARHRRTHLPEPPYRCGQCGKGFSQSSGLLQHATVHTGERPYICAVCGRGFGRHPSLIRHQKSHSGERPFPCQECGKRFTQSANLARHLRTHTGETPYLCGECGRGFSQHPRLVAHRKAHHMGPPPPPPPVHSCADCGLLFPQALALARHRAAQHGGEKPFRCAQCGEGFGHRSNLRRHQRGHGGERPYRCSQCGKGFGQSSGLVQHQRVHTGEKPFRCPDCGRGFRYSSNLAQHYRGHTGDRPFRCEHCGRGFTRSSHLLRHRATHGGEDGDEDCGPGGVPVPIIKATSPTAISQESPKESGNAPQVTEPLSQPE
The following text describes a protein:
Function:
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis, transfering GlcNAc-1-P from cytosolic UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol embedded in the cytoplasmic leaflet of the endoplasmic reticulum membrane.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MFETRFIPGLVVVVLAYVLNGLKGALNQEQFFAFMGYMVLSFFAYVLSYWMIPKIAQLTEKADIFGYDINKKGSDAGKIKIPESLGIVPATIYLIFNILGILFTRAYMPDLILSHISGLLAITFIVFLGFADDVLDLAWRYKLLLPPIASLPVIVAYTGGTQIVLPQLIRPYLGQTIDLGPIYYLYMIMLSTFQSNAINIYAGVNGLEVGQSIIIALSIAVYNIIEISTQQQHLFSLMIIVPYISSALALYNYNRYPSKVFVGDVFCYWSGMTFAVAAVLGHFSKTLMLFCIPQLINFLYSLPQLFGIIPCPRHRLPRYDQSTGLLYAIKTNLTLINLVLLIKGPTSEKNLCRVLLSFQILCTIIGFGIRYLGSQMFF
The following text describes a protein:
Function:
[Isoform 1]: Kinase that contributes to activation of the hypersensitive response, a form of programmed cell death, upon fungal infection; [Isoform 2]: Secreted protein that contributes to activation of the hypersensitive response, a form of programmed cell death, upon fungal infection. May sense the presence of fungal material and relay the signal to WAK17 isoform 1 (Probable).
Subcellular Localization:
[Isoform 1]: Cell membrane; Single-pass type I membrane protein; [Isoform 2]: Cell membrane; Peripheral membrane protein. Note=Associates with the plasma membrane via interactions with WAK17 isoform 1.
Sequence:
MPSRSPACRPRGRNRRSAADAVARPLALALILVSTLPRAAHSQDLALPPVQPRGVRRTMTCDNIPEPFGTRSRGASRLPGFEVTCGPNREAMLSIGGDAYMIDFVSVSGSYVVVFAEPITQVCYDGKGKPTPDTGTGAKSSEGTTTTFTWSLEGTPFTFSKSNKLVNFGCNRTLMANFFIVPGDSSPLYTSCTTTCNTLQISGSCLGEACCEAPMDQVNGAKAFSLSFERTTANGTGEEDGTCSAAFFLDKDETVFTFSGDEVRPLKTALLPPGERRMVLDWAIGSTSCEQTQSYTFEKLCKYGTCVDAPTGAGYLCKCPSGYDGNPYVSDGCQDINECRNYNSNNCTYQNLCNNTLGGYTCSCPENNIGDGYRTGTGCNTTLATPVSPSQQPQGINVCDHPEKNPCTYIKYCIDLEGVVSCACPEGMSGDGRKNGRGCCFSCQKHFPLDTVLGVSLVLMVTTTTAASCYCWAVKKRELGRKRAELFRKNGGLLLQQRFSTITSQGEDQYSSKIFSAEELKAATDNYSESRILGRGGQGTVYKGILPDQTVVAIKKSKVFDESQVEQFVNEIAILSQIDHPNVVKLLGCCLETQVPLLVYEFISNGTLFQHIHNRNATRPLTWEDCLRIAAETADALAYLHSASSIPIIHRDIKSSNILLDGNFVAKIADFGASRSVPFDQTHITTLIQGTIGYLDPEYFQSSQLTEKSDVYSFGVVLAELLTRQKPISAARPEDSCNLAMHLVVLFNKGRLLQEIEPHILAEAGEDQCYAVAELSVRCLNVKGEERPAMVVVASVLQELRRSFTIDQAVGIKDESIQENSEQEEKHLHESRSIPSLQSSEVSTQCSMEAKMSSFC
The following text describes a protein:
Function:
Is essential for plasmid replication. Nicks the positive strand at the plus origin of replication.
Sequence:
MAKEKARYFTFLLYPESIPSDWELKLETLGVPMAISPLHDKDKSSIKGQKYKKAHYHVLYIAKNPVTADSVRKKIKLLLGEKSLAMVQVVLNVENMYLYLTHESKDAIAKKKHVYDKADIKLINNFDIDRYVTLDVEEKTELFNVVVSLIRAYTLQNIFDLYDFIDENGETYGLTINLVNEVIAGKTGFMKLLFDGAYQRSKRGTKNEER
The following text describes a protein:
Function:
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein.
Sequence:
MENIQNGRQYYNHMEHRDIHNNNEYIKVDWSDIINEPTGVRSADFSWNLSYKIYTKSQSCCYKSLAYILGPIFALWFGLSFGCQSFMHIWCYQPCLSRFRIRFSFLQRLNTIILDATCVPLMKACSNIFSNVNVRYEKMTADFSPTHRQRERVIQIEPRPTEVIYDDVKNQK
The following text describes a protein:
Function:
Substrate-recognition component of a cullin-5-RING E3 ubiquitin-protein ligase complex (ECS complex, also named CRL5 complex), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as DAB1 and IRS1. Specifically recognizes and binds phosphorylated proteins via its SH2 domain, promoting their ubiquitination. The ECS(SOCS7) complex acts as a key regulator of reelin signaling by mediating ubiquitination and degradation of phosphorylated DAB1 in the cortical plate of the developing cerebral cortex, thereby regulating neuron positioning during cortex development. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Also inhibits prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Nucleus.
Sequence:
XRPPQLMVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDAFPRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVEPST
The following text describes a protein:
Function:
Probable transporter.
Miscellaneous:
MISCELLANEOUS: Present with 414 molecules/cell in log phase SD medium.
Subcellular Localization:
Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein.
Sequence:
MDASSVPPKVDDYGMYTTEISHHNPIELKNLLSSSDSRRNSQDEDSLPNNTNLIKEIDWQGEKVKTYPLNYQTVPLVKLQVIACLIMFVVFGMNDQTVGALLPTLIEYYHISRVDVSNVFIVQLCGYVMASLSKERLNKHFGMRGGMLLAAGLCIVFLIILATAPSSFYVCMFCGLPLGLGIGILDSTGNVLMGSLLVHKNELMGIMHGLYGAAAMVTPPLVSYFVEWGHWSLFFLIPLFFSIIGMIVIFPAFKFETASKYDYLCSVENKESNNDVEEAGDNSLMESTKASPGFFELLRNPAIFLYSLYLFLYLGAEITTGSWFFSYLLETKSSNKVAMSYIAASFWTGLTVGRLCLGFVTERFFENEYKASKAYAFLTLSSYTLFVLVGLINSSSVFYFVVLFFVVFCCGTFIGPLFPNASIVALQVLPKRLHVSGVGVAVAVGGCGGAAIPYLAGVIAHTVGIQYIPLLCWIMVALFTLEWTLYPKFIKGHEEYF
The following text describes a protein:
Function:
As part of the CRL3 E3 ubiquitin ligase complex; polyubiquitylates monoubiquitylated RNA polymerase II subunit RPO21 to trigger its proteolysis; plays a role in global genomic repair.
Miscellaneous:
MISCELLANEOUS: Present with 815 molecules/cell in log phase SD medium; MISCELLANEOUS: In contrast to other members of the family it does not integrate a functional E3 ubiquitin complex.
Sequence:
MKSLQTLCEISLMRNHSNIQSVSNVPYHLLKRILQKVKIPQLLKLEKSNVLLIFDDDELWLEFLRQDFPTNVHEQFVSKRDIICKYYFDFVKENDIELYHSNQDLLKSCVRQSVVKDIRNNKYRIPYRMLYSKYQQEVEKKQEESAERLRLEMQKLQQEREKKQTIVVDHTVYFKKRNTKKTTRLHNEPHSQLYMKSLKDHESRLKHFKDGGFNIAKRHAQRVAFGGQAGGQSSSPKKGPLSIKPEPVKVNRQMDNVTAEKKDVTQPITPVKKRRSESPSIFLNRKKPALFRPTPKTNAAGSRPHTTAITNDHRTTSHPYPHKDVVTSISSVTANPVTKGHKKKKSGIFVRNAGSDGDSFPHVTATGPTTRPYIYEPRK
The following text describes a protein:
Function:
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
Sequence:
MANIAESAVLVSSASSAQAVAKLTQVRGPTSGFDKAQHIIGSYSTMGFQATNYGLARSIAQRMIRKQPPSKVYQIKDGKYVLVPPDVGEDGKTLQQEHVYPNLFMGVTANLMGTGCREAVRFLVQEGVVHRSLEASAPASADGTDDQLMFARLKREYVETYGGPPHPDEEIPRAHSFLCAIVVSGGGVEHDLRRACTAYTLHHYASEAQGHVSSTVSSEATAPPKGLQQRAEKPLGTRAAAGTAKPARFGNVEYPRQGSTGSELFDCLMRTFVQRLCARQARLRAAAMAKPIPDKYDDVCSWSVTPSEVWALCGLWLVDMLAEALGAVRSCTSRLTSGSAVGTAESVTANGKGPEADRDAHIATSASYRAEALARARTTVVYWAALQQVSLFSPSFVDGDITSYLLPTPAPAARPAHRKGGPVADENAGNSKELKRSRKASSSSSTSATAVKVKPPVVERLQVDLVRDVYSINKLAMLSKKTGMLICGGGVVKHHVCNANLMRNGADFTIILSNGQEFDGSDAGAKPEEALSWGKVRMEGAFVKVYGEVSTYLPLLLAEVFVPAVRQRRATDDAQPRRKRSSRGARPPQDVSGHSHLCRGE
The following text describes a protein:
Function:
Probable ATP-binding RNA helicase. May act redundantly with the P-granule component glh-4 to regulate the formation of the granular structure of P-granules in embryos. Plays a role in positively regulating the localization of pgl-1 to P-granules. May play a role in transgenerational epigenetic inheritance. May protect somatic cells from excessive apoptosis during normal development.
Subcellular Localization:
Cytoplasm. Cytoplasmic granule. Cytoplasm, perinuclear region. Note=Perinuclear localization in germ cells but disperses into particles in cellularized oocytes. Component of P granules.
Sequence:
MSDGWSDSESAAKAKTGFGSGGGFGGGNNGGSGFGGGKNGGTGFGGGNTGGSGFGGGNTGGSGFGGGKTGGSGFGGGNTCGSGFGGGSTGGSPYGGASSGFGGSTATSGFGSGEKSSAFGGSGGFGGSATGFGSGGGSFGGGNSGFGEGGHGGGERNNNCFNCQQPGHRSSDCPEPRKEREPRVCYNCQQPGHTSRECTEERKPREGRTGGFGGGAGFGNNGGNDGFGGDGGFGGGEERGPMKCFNCKGEGHRSAECPEPPRGCFNCGEQGHRSNECPNPAKPREGVEGEGPKATYVPVEDNMEDVFNMQKISEGLMFNKFFDAEVKLTSSEKTVGIKPCKTFAEANLTETMQKNVAHAGYSKTTPIQQYALPLVHQGYDIMACAQTGSGKTAAFLLPIMTRLIDDNNLNTAGEGGCYPRCIILTPTRELADQIYNEGRKFAYQTMMEIKPVYGGLAVGYNKGQIEKGATIIVGTVGRIKHFCEEGTIKLDKCRFFVLDEADRMIDAMGFGTDIETIVNYDSMPRKENRQTLMFSATFPDSVQEAARAFLRENYVMIAIDKIGAANKCVLQEFERCERSEKKDKLLELLGIDIDSYTTEKSAEVYTKKTMVFVSQRAMADTLASILSSAQVPAITIHGAREQRERSEALRQFRNGSKPVLIATAVAERGLDIKGVDHVINYDMPDNIDDYIHRIGRTGRVGNSGRATSFISEDCSLLSELVGVLADAQQIVPDWMQGAAGGNYGASGFGSSVPTQVPQDEEGW
The following text describes a protein:
Function:
Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane.
Subcellular Localization:
Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Nucleus, nuclear pore complex.
Sequence:
MAFNFGGASGSASLTGTGFGAPTTTSASTGFGFGTGGTGFGPLVCSAGPGPAPSAAAVSFGGFGLGPAAPVFSFGSGLGGAAGAFGGFGSTTTSAGTGSSFSFSTPANTGSSLFNTQSKGFGFSSAPAPASGFTGALGGGALGFGGFGALQNTQQGGVFGQQAPPPCSQLFNTASALSAPAVLSDERDSILARWNQLQAFWGIGRGYYCSTTPPVEFSQENPFCRFKAVGYSCVPDVRDEDGLLALALGKREADVRLQQQQLVESLHKLLGGAHTLSVNVEGVRALPDDQTEVIIYVVERSPNGSSKRVPASTLYNFLEQVNIKTQLQQLSVIMTVSRTALSPAQLKQLLQNPPAGVDPIIWEQAKVDNPDPEKLIPVPMVGFRELLRRLKIQEQMTKQHQTRVDIISTDISELQRNQATTAAKITQYKRKLMDLSHRVLQVLIRQEVQRKSGYAVQLDEEHLRVQLETIQSELNAPTQFKGRLNELMSQIRMQNHFGAVRAEERYRVDADLLREIRQHLKHQQEGLSHLISVIKDDLDDIKTIEDGLHDSVHTRSSKLS
The following text describes a protein:
Function:
Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of pseudouridine at position 914 (Psi914) in 16S rRNA. Is not able to methylate uridine at this position.
Sequence:
MTYNIILAKSALELIPEEIKNKIRKSRVYKYDILDSNYHYKAMEKLKDKEMRGRPDIIHISLLNILDSPINHEKKLNIYIHTYDDKVLKINPETRLPRNYFRFLGVMEKVLKGERNHLIKMEEKTLEDLLNEINAKKIAIMTKTGKLTHPKLLKEYDTFIIGGFPYGKLKINKEKVFGDIKEISIYNKGLMAWTVCGIICYSLSF
The following text describes a protein:
Function:
tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Sequence:
MEQQIHQAVEIALSGTADPTLKNQAFEFINHIKSTEEGYKACVDILIKSSNESINDGLKFFVYQVIDENIDKLSQEQVFTLNQELFKCLSSYINNNLQDPTHLRNKFAQILAKQFCQVYINIYPNFIKDLLELINVSEATSTNPNNLLAIDYYTRVLIGIHSEIGDKYITRSQEIHNRNNLLKDAIRTQDMQQMVTSWIQILTNPSFAHSEEILNNTLKIVGQYVSWMEISLFISPEFINTVFSFLQNSKLRNTTCETLIDIISKKMAPQNKLELLSLLNLTEFIGTLNLIEKNKNDDDDEDEDVEFMEFVAKLLNQIGQELLIVLENQSGLLEQVNAQLFKLWPAILGCLNHNYDDVSQNVFPFLQQFLTLSKKNPQLYTVDLMSTLLNKLILKMRFDDDDDGVSDEDTQAQFLDFRAKLKSFQDTIALLEPQLYLEAIPVIINESIFETNVDDVNWRKVELGLYQLNGFSDSIRNNVFQISRNEINQSKPYLIFQEFLIKLINSDLIMKINHPMIQSNFFELIVKHYNFLVSRESNFELIIKILQIFTSPLGLFNENEKVRIRSWYLFFRFIKLTKPKLDNEALIESIVVKMQPLLVIKAELPTKDEDDDIVENGNFNNQQYLFETMGLLISLIPNELSQLKSKLIDLIFQPIFNDLEKCISIPESQREPIVILQAHHSLQAIGTLVRGYDYESGLKFLPDVVAKIDNAAQVVLITLENFSSHEMIRDATRFAFARFIPIFKSDNDNNNKNNLIISQHLSKLITIIWSSSNLKISEYSDFLSFLGQIVHNFRTDDNIYQLLNNFITPLFQKIFQVLQNPVTEDENLRPDIIRDKNSLKRATLNFISSIVMNHLSSLLITESNKQELPEIIGKVFEYSYDLSDTTTSKLAIVQLTNFVNVFGGSGGKLDDKEDKYSENLPPIEGIDEFLINKVINLSFELPFQKQEFNLNDAQYRLIAQEIAILLKSFELKKHDEFIVVLSNYLLNMGLSQDLCNDFCLNLHNLDLKDFKKYFISFINKMKSGK
The following text describes a protein:
Function:
May play a role in vesicular transport from endoplasmic reticulum to Golgi.
Subcellular Localization:
Endoplasmic reticulum. Golgi apparatus, cis-Golgi network.
Sequence:
MEKINLNLSTRPKASILDKPLSRGKGEVSLSSYALLFSELVQYSQSRVSTIPDLQTRLHDMGKDVGCRIIDLYFVRERNSKRETKLINMLLFIKTTLWKTLFGKEADKLEHATDDECTYYIIEKEPLVNKFISVPKDKGSLNCAVFVAGIVQAVLSNCGFTCQVSAHWHKGTTYMVKFEDHVISRDKQLEDK
The following text describes a protein:
Function:
Probable transcription factor. Required for initial outgrowth and pathfinding of axon growth cones along the ventral nerve cord (VNC). Involved in specifying neuron identity, in concert with nuclear hormone receptor family member fax-1, or with transcription factors unc-3, cfi-1, or hlh-34, perhaps acting via positive feedforward loops. Establishes electrically- and chemically-interconnected neuron circuits, acting by modulating the expression of neurotransmitter pathway genes, neurotransmitter receptors, neuropeptides, and neuropeptide receptors. Required for cholinergic and glutamatergic synaptic communication. Plays a role in locomotion and mechanosensory response, perhaps via regulation of chemosensory receptor expression, and is required for expression of glutamate receptors, including glr-1, glr-4 and glr-5.
Subcellular Localization:
Nucleus.
Sequence:
MSDNLLNGANGASTVSQFQEKVKDLGVSLHDFTAYYPSSLDTVSASLRPISDPSSDGAFKKIKTEGLGGSVFGSSIAGVTNTPARLCSLERPESERLNSRRRHRTTFTQEQLQELDAAFQKSHYPDIYVREELARITKLNEARIQVWFQNRRAKHRKHEKQLNKAINPPHSFLSNPANTLMRQGMYPAALNRDGFWYQSYQRPMPYPTASPSYSNSFTNPIANFGHSITSFQADDEFYQKSLALRMTTTPSAATAATSLANINYQQTQPSEASTNPPSI