lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the NatC N-terminal acetyltransferase, which catalyzes acetylation of the N-terminus Met of L-A virus Gag protein. MAK10 has a role in the propagation of L-A and M viruses, perhaps in the viral assembly. It is apparently directly needed for optimum respiration.
Miscellaneous:
MISCELLANEOUS: Present with 1970 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MEVDSILGSLSITDDFDQLVDVTSLFDELCSKLKPEAIVKDPRFDLFEGTHSLEVNNSKLDSSLIELTAEEIEFDVNVAYDPPLASVAAIADRLLRCVISWLNDYQTLPTTVLSCRYTESLLSSLVKGTTAGSSWCTGNILYDKVLGSCILGVCYLTKFVQKLLSAGIVFEEEDLNFNNMGFNTFDNLPGQDVVINSLTESLQILEAYSDDSLHLTMLKHILKIIICLVHLEDHLTDYSTKTSHLDELIENANSVNGIFPQLQLSPPKGAFSTYIQKHRSNQFPPRKITKLPTDYSGFITLANDVKTILLVDKAESALETYQFAKFFNKLEQRHVIARILFPLFFIRDDRTVLGKFSYTQFYLLHVKEFSAQTPSEFESSIGNELIQESSNMLLEWYQNCSQNTCRYRQGFNRQLILWDSLQAQFESVNSQVYCSWTYFMKLSSMIEFSLKGFDLDIYKPFEAYSMFWYVYYLSHHLETFLKDSQNDIESNINAIHSMNKKLKKLKAGEKKDQLRLKYRFAMDNEMEQLQATKQFLNYLLKEINITKSLCLIEVFQFAILKSFGLIDNKNSTPSKFSNERLIHNLRFKPFNSIGVPELPEYEVFQQTLKDFVIEEKGAAFDIKLERATNFIETEVRNVVSSIDEIMQGIKGGDNNGVLVTGTRLVQELSLEYYCKLKHTSKALSVNSKVIVNTLKKNIKNKDSHEYKVELVHTTEGWNYFPIQTLRIKQDRYK
The following text describes a protein:
Function:
Choline transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MTTPLTHAQTGLRDAPPPKRKLTNLPFFLAFIVCLALVIPFSLVFALSSNLKRLLNGYDSCGNTCGVENKPLYYRNCSELNMRDKPIAMMKYYDVDPLCIFSLQKVLPDKCVEKCEPPNQLIFNRCYPPEADTNLDSKSRNFKQMIEIPHVFLSNIATITAMSFTGLILSFGLFACLRCHVAATFWTLTLFQSFVALAAAALFWHKYINSGSTMYLFLALGAMAYFTSVFIYFFVLYNTFTMVRRVYHQALNAIFRAPMILVQPLLTITVLISVITTMIFLMLLSLSPSGWPEISDEGPLVYEFATNEATLYYLIYLAFLGFWIYSFGEGFQAMVVSGATVEIYTTKDKTSLRHPVRKSYHTLLHHHLGTVACGSLLATIFAFMRGLAVYVIRKVYILTSMKGQPFCKSLKRAVELLRLNLVETIALTGFNYLIIYGFSLLIVVITVGVGVWMNLDSKFTFYVRLGILFGAVSASLVAHFVLKVLHTTTETIFLCYSEERIAGPVTPQNTATKK
The following text describes a protein:
Function:
Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.
Sequence:
MLQRLFLGFAPNDTQRQQLLQLQQCVTPQLTLHAKPVSKANFHLTLAFLGLANQAQKTQLLEAVDKLHRPRFTVQLDKLAVWPKAQVCCLKGDMVSPALALLASQAQNLAQQLQLHQSEHPFRPHISLFRKTKYFNAFDNELALKDLAKTPITELTITPDQIHLYLSSSSDSGVEYHILHSWPLE
The following text describes a protein:
Function:
Involved in telomere length regulation.
Subcellular Localization:
Mitochondrion.
Sequence:
MLQTRLFHACAALARAASRPVPKPTSEIPDVSTFLAKIGRQCSEHAELYENKWENLFMWDGPKLKEKGVPVQQRRYILQQVERLRQGGPVREIREGKKSFFGGERKRKEKVAKWRAEQRHAA
The following text describes a protein:
Function:
Transcriptional regulator that specifically binds to GA-rich elements (GAGA-repeats) present in regulatory sequences of genes involved in developmental processes.
Subcellular Localization:
Nucleus.
Sequence:
MNKKIMSILVLERDQALFAKKESLAARDEALLQRDKALTERDKALIERDNAFVRFNTIAEVIQSEEDEDIADQKEEESRRIIRRRRYSRIGGFWFMEASQLRINRIRGVATTSRDGRRQKTMSGSLVNFSGCRTYKKERRILVYRIIETATETSETIFLKVAKIQDRGMKMKILGALVNVINVERRQACDE
The following text describes a protein:
Function:
Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.
Sequence:
MISMRTSSVVGYVPQSSEPHHCGYCGKNGSRHAAGIWGHRLRVSDYQILMDRGWRRCGKFIYKPDLQKSCCPLYTIRIEALECVISKSHRKVIKKVMNYLQGNTTLEELKRKHEEGNDTQQIDTKSHNDNVKKSIDGEKGKNQRDASVLHQNNVEAKATSRGPDPTKPKRRKAKDIRREKKLEKLSRESDMTTEQIKKHIEEAKEKEVKENIQKRVQILDELFKQMAPTLTPGHKLEVKLVLADRSLPQFQLTFKKSHEIYQKYQMAIHNDRPDECDEGQFKRFLIDTALMFERSPEFPSTGCGTFHQQYYLDGELIAVGVLDILPQSLSSVYFFYDPDYAFFSLGVFSCLRELSFARQINRDTPSMQYYYMGLYNYDCKKLTYKGQYDHSYLLCPETYVWTPLPECIPKFKVTKYSRLYHGSENNNPETDYNKVHIMFMNRIMTFPVYCKLSESYETEVAENYAKHVGLTLCRRMLLHRS
The following text describes a protein:
Function:
Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis.
Miscellaneous:
MISCELLANEOUS: Plasma contains 4 isoforms, which are named isoforms Se-P10, Se-P6, Se-P2 and Se-P1, according to the number of selenocysteines they contain. All isoforms arise from the same mRNA. The 3 shortened isoforms terminated at the opal stop codons at positions 264, 282, 371, when selenocysteine has not been inserted.
Subcellular Localization:
Secreted. Note=Passes from plasma into the glomerular filtrate where it is removed by endocytosis mediated by LRP2 in the proximal tubule epithelium.
Domain:
The C-terminus is not required for endocytic uptake in the proximal tubule epithelium.
Sequence:
MWRSLGLALALCLLPYGGAESQGQSPACKQAPPWNIGDQNPMLNSEGTVTVVALLQASUYLCLLQASRLEDLRIKLENQGYFNISYIVVNHQGSPSQLKHAHLKKQVSDHIAVYRQDEHQTDVWTLLNGNKDDFLIYDRCGRLVYHLGLPYSFLTFPYVEEAIKIAYCEKRCGNCSFTSLEDEAFCKNVSSATASKTTEPSEEHNHHKHHDKHGHEHLGSSKPSENQQPGALDVETSLPPSGLHHHHHHHKHKGQHRQGHLESUDMGASEGLQLSLAQRKLURRGCINQLLCKLSEESGAATSSCCCHCRHLIFEKSGSAITUQCAENLPSLCSUQGLFAEEKVIESCQCRSPPAAUHSQHVSPTEASPNUSUNNKTKKUKUNLN
The following text describes a protein:
Function:
Required for spermatogenesis and is involved in the suppression of retrotransposon transcription in male germ cells.
Subcellular Localization:
Cytoplasm.
Sequence:
MEETYTDSLDPEKLLQCPYDKNHQIRACRFPYHLIKCRKNHPDVASKLATCPFNARHQVPRAEISHHISSCDDRSCIEQDVVNQTRSLRQETLAESTWQCPPCDEDWDKDLWEQTSTPFVWGTTHYSDNNSPASNIVTEHKNNLASGMRVPKSLPYVLPWKNNGNAQ
The following text describes a protein:
Function:
V region of the variable domain of T cell receptor (TR) delta chain that participates in the antigen recognition. Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids presented by MH-like protein CD1D and phosphoantigens presented by butyrophilin-like molecule BTN3A1. Upon antigen recognition induces rapid, innate-like immune responses involved in pathogen clearance and tissue repair. Binding of gamma-delta TR complex to antigen triggers phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) in the CD3 chains by the LCK and FYN kinases, allowing the recruitment, phosphorylation, and activation of ZAP70 that facilitates phosphorylation of the scaffolding proteins LCP2 and LAT. This lead to the formation of a supramolecular signalosome that recruits the phospholipase PLCG1, resulting in calcium mobilization and ERK activation, ultimately leading to T cell expansion and differentiation into effector cells. Gamma-delta TRs are produced through somatic rearrangement of a limited repertoire of variable (V), diversity (D), and joining (J) genes. The potential diversity of gamma-delta TRs is conferred by the unique ability to rearrange (D) genes in tandem and to utilize all three reading frames. The combinatorial diversity is considerably increased by the sequence exonuclease trimming and random nucleotide (N) region additions which occur during the V-(D)-J rearrangements.
Subcellular Localization:
Cell membrane.
Sequence:
MILTVGFSFLFFYRGTLCDKVTQSSPDQTVASGSEVVLLCTYDTVYSNPDLFWYRIRPDYSFQFVFYGDNSRSEGADFTQGRFSVKHILTQKAFHLVISPVRTEDSATYYCAF
The following text describes a protein:
Function:
Acts as a positive regulator of hedgehog signaling and regulates ciliary function.
Subcellular Localization:
Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Nucleus.
Sequence:
MTQLIACGVGQCGVQMASSFTETYMKEAQNYVDQDAFHRLFYETSDHQYIARTVLIDTERKAITDILSDKFATRNWKYDKCSIWAEGCGSGNNWAYGYDKNGFAAKNEVMDRLQHQAEKCDRFGGFLFFQSLGGGTGSGLGSRITECVRDTFGPRAQIVNNVVWPYTFGGVMVQNYNSVLSLAALIKNSDAVVVTYNDTLHAICAAQKGPENVTLADMNDVFSRNLAGLLLPSYELCTVPIWSQPLSHLVQIPTRRLLHIFGYPIESDVAHGFSNYNWSSLIDNVLSMVATGNFVGRSIRQIRSIIDPRRQLPIKKCDAIWTVFRGIETNQAKQYMLNHDIMKCQHFFPADNDDPLLVSTSTRKFLGYDQYTTVMANSQVIIDPLEDLLQKFHNMIETGAYIHQYLDTGMEKSKLQEDKLFLEQVLFDYKTM
The following text describes a protein:
Function:
Has oligopeptidase activity and degrades a variety of small bioactive peptides.
Sequence:
MTTATTSQTALRSRKDVPLSDCWDTKSLYASREVWQDELKKVGAEGAPFWPHLSENNFDIKQPSSLRELLTTVFSIERTLDKLYVYAHLTYDEDIANQEAAADLKSITFLLTSFVEEISWIQPALIALPQQVVNMLLASPELQEYHFYLKKLFRLAPHTGTSREEKILASSFPALEVAYKTFSSLTDSEIPFGEAVDSEGKSHPLSHALASLYMQSTDRELRKNTYQKQCQRHHGYRLSLANLLNGKIQAHLFNAKARDYDSCLEAALFQNDISTSVVTTLIDTVKQHTHLITEYFQLKQKALGLSDFHFYDVYAPLVASEASRHYSYQEAVTLICDSLSLLGNDYVETLRKGLTSDGWVDKYENTNKRSGAYSSGCYDSKPYILLNYTGTLYDVSVVAHEGGHSMHSFLSHKHQSYHEAQYPIFLAEIASTLNETLLMEFLLKQAPSKEEKIAILSRSLDTVFATLFRQTLFAAFELEMHSAAEQGLPLTEEFFSQSYEKLQRLFYGDCITFDEHSCIEWARIPHFYYNFYVYQYATGIIASLCFSERILSGEEGAQEAYLTFLRSGGSDFPIEILKKSGLDMTSSAPMLKAFSYIERKLEELASLL
The following text describes a protein:
Function:
Involved in a cysteine salvage pathway from S-alkylcysteine. Catalyzes the oxidation of N-acetyl-S-benzyl-L-cysteine and N-acetyl-S-methyl-L-cysteine to (R)-N-acetyl-S-benzyl-L-cysteine sulfoxide and (R)-N-acetyl-S-methyl-L-cysteine sulfoxide, respectively. This pathway is likely important in the catabolism of alkylated cysteine generated by proteolysis of alkylated glutathione formed in the detoxification of a wide range of electrophiles.
Sequence:
MIRLSILDQSLIGEGETAADTLQHTVKLAQMAEECGYHRFWVAEHHNNDEIAGSAPEVLLGYLAASTRKIRLASGGVMLQHYSSYKVAEQFHLLSALAPGRIDLGVGKAPGGFQLSTDALQAEYKKPVRQFDEKLEELTHFVRDDFPDTHRYAALRPRPQVDRKPGIFLLGGSTESAISAAKLGISFVFAYFINGEEEVLKEARRAFDAHLPPGSEAEFHLAPAVFAAHTKEEAEKHIVSRESIKVVLKDGRKVNVGSREQAEAYLENVTEPYDIIVQKTGIIAGTKEEVAEELTRLSGTYKINDFVIFTPIKNAVEKQLSYQLLSDAVLAAKR
The following text describes a protein:
Function:
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MEKTGLRAFLAVILSMAILFGSQYLYTKYYKPSEVQQQPVEVKKEDKKQIPQSVQPEPLKKEEPKQISKDIKYREVSIENDVFKVILSNEGATIKSVELKKYKDNSGKPIILTSSDILPLSISKDGKFNYSKVMFNIDDSNVSFKNSNQAVVVFTYNDSNIFLKRTFFFNKTDYVIDIKEEVKGFGSYYVTLGKDFGIFEKEDSPHWGPVILKEADRIELNPSKIKETNTYKEGVKWIAQEDKYFFSAIVPVTKANQFVVLPYNGDALTGVEFNDGINSYRVFAAPKEYDYLKKFNVGLEHIVDFGFFSIIARPLFWFLKLLYSLIGNYGIAIIILTILVRIPFIPIVNRGQKSMQKLSELQPKLMQLKEQYKNDPQRLQKEMMELYKKYKINPMSGCLPMLLQIPVFFALYKILTIAIELRQAPFMFWIHDLSAKDPYYVLPIIMGATMLIQQKMTPSTADPTQQKIMLLLPVVFTFLFLSFPSGLVLYWLINNLFGIAQQFYINKKIKKSV
The following text describes a protein:
Function:
Positive regulator of Notch signaling. Maternal neurogenic factor involved in Notch signaling-dependent neuroectodermal specification during early embryogenesis. Functions cooperatively with amx/TM2D3 and bisc/TM2D1.
Miscellaneous:
MISCELLANEOUS: This protein is named 'amaretto' after the sweet almond flavoured Italian liqueur because of phenotypic and molecular similarities with TM2 domain-containing protein almondex.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MRIFYGLLAFLVARQHDAQAIQARSDKEQPQTVVSGTAVQSVVPVQAQLGSGMGPSSSSSSASSASGGAGNSAFYPLGPNVMCSFLPRDFLDCKDPVDHRENATAQQEKKYGCLKFGGSTYEEVEHAMVWCTVFADIECYGNRTFLRAGVPCVRYTDHYFVTTLIYSMLLGFLGMDRFCLGQTGTAVGKLLTMGGVGVWWIIDVILLITNNLLPEDGSNWNPYV
The following text describes a protein:
Function:
Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.
Sequence:
MEYVKLINCMRCGMCLPQCPTYKETFLETASPRGRVALMRKIEEGDLEVSERLLEYLSLCLDCQACASACPCGVNAGEMVAGYRCERRDGKELSTMENLILRRLLPHPDRLEAATAPMRLYQRTGLQKVVRKLGILKMFPPTLERMEGLLPELPVKPLRQTIDEVTPAVGPERGTIGFFLGCVMSLVFSEASYATVKLLSSLGYRVVTPKAQKCCGAPNMLSGDREGLLDAARFNVDLFAGHRLDFIVTDCGGCGAELKKYGHHLEDDSRAATFSAQVRDITQVLALHADELKAKLNPLSLKVTYHDPCHIAHCQGIRQEPRTLLRIVPELDFRELPEADACCGSGGTYNIEKPEMSDRVLRRKVENIKATGADVLVTANPGCLLQLRKALAQETPPIRVLHVTEVLAASLLPPLL
The following text describes a protein:
Function:
ARL8 effector that promotes the coupling of endolysosomes to dynein-dynactin for retrograde transport along microtubules. Acts by binding both GTP-bound ARL8 and dynein-dynactin. In nonneuronal cells, promotes concentration of endolysosomes in the juxtanuclear area. In hippocampal neurons, drives retrograde transport of endolysosomes from the axon to the soma. Positive regulator of macroautophagy in dendritic cells. Increases autophagic flux, probably by stimulating both autophagosome formation and facilitating tethering with lysosomes. Binds to phosphatidylinositol 3-phosphate (PtdIns3P) through its FYVE-type zinc finger. Positive regulator of osteosclast bone-resorbing activity, possibly by promoting late endosome-lysosome fusion by acting as an adapter protein between RAB7A on late endosomes and LAMP2 on primary lysosomes.
Subcellular Localization:
Cytoplasmic vesicle, autophagosome. Lysosome.
Sequence:
MALGRAPKIISEMKEYIQDLKRNYEETQLPVTDDSVPLHKLCAKLEYMLQIDMKPSARSGMFASKRDYWDYIYQCLYKVKGLDDGIRFVRAKNEVKTSLGRGRAFIRYSLAHHRLGDSLQQCFNNQKVTRTWYNPNSLVLNPSLYGPLVNDLYDLNDLQFDLAPSGHDLDASWPTHSRHVMGPSAGMYSSWQPPSRTESLSSLSSQPSTLDGYPSPTAESRPTIGEERALHQAQSELEECEQVNRELRKRIVQLESENDDMHRLAMETEERMSSMQSELERKVQQLQYELEKSSKESLDITEKMNRSEENWKKKIEDTEKVNSDLCSRLEATNLQHGSQAKLWQEAERDHQSKLIEAERVLAEVKVELTGVKGELAAIKGMEMKKDKTVQSLEEKVSAMEIKNVELFEKMEGMVESKDAEVSNHLQSANKVHELLDKLSEAESKNQELRGEKGALRRQIDLLEDNRSSQETDIVAKVAELELVVSKKETEEVMGENIAAQEVKHENLVQELQATISALTDEKLTLKSDLKEQLQKRDDSSKSLESTQSELLQSKTAIVSMQQKLVELQKDTERLRKELHAAGVQNEALKARIKHTEGVCQERQKEIDDLDKEMKEQISKYTEVNGLLKKERERTSSLETQFKDSQDKVSEVEMEKKNIMQQLENVQNILSFGEESSITRESLQGSSDEPDSSDPKGTLISQHLTRMVSQKNDALQSVKELQLENQRLSKEVKTLTEKNMHDSEDASHTADQVLKTEKELGALQQKLDNMGKMLESKEKGLQTQSIERQRIEGQLQEAMNEKEQLETDIVRLRLAIDSKDKERDLLIVEKTKLELARDGLEKDLLVSRQEKNEKEKKLREQGEVISQLMADIEHLKTQKQEAEEGRDGIQKQLNRERLTTRELEDTVEDLKRLQEETVTLEQVYEERKTKMTQEHGDKVEFLTEQFQLLKEEQEKTSGERLHYQEQAEDLSKELDDVKERCEILETENKAVRDKNNDLNLEILRMQEEVELSKTERNEITEKLEQVSTETSRSLQETKLEMEQLQGKVEEEQERSRIIQKLEGALEKEKENVQVAEAKAQGAEEETQRVQSTMKEEISGLKFQLSSEAMQYQQTLQGYQEQESDLENLKVQSEEQHETILALSNEIETVKKQSNQDKINFQKKLSEQENEVARQEKQITIHEASVEELSRCLEEEKRKSVSVQSEVLELRNANGSRVASLEEELALAQDDNEQLKKQLVKLIKEKDTLWQRTEKLEYNRKMKASERWMDDRQVTQCMSCLCEFGLTVRKHHCRLCGRIFCAKCTSFFVLTSHSKKKSRVCEQCYVGHQHSLEAASINTSIISTNSYEDNLDDGPPNQRTEDVPGGSSYVASDEGMSDVMSESVNSEPVRMEDVDESLRIVGMNAIAQGDDKHMLSREDMVPSPNLTSENTASEPDFDIIGEDEVSAARQDEKENEENEQEIQPEESSSSPQDGTDGQLLTAEELEGEGITGEEVTVAAYQKYNLPVAINDVGLMLCWEFVSSPKSIGFSVIFQDSSDSTSPHEELIPLCKCNSHQHAVQGELLARKPGVYTLIFDNKFSRFTSKIVKYSLHIKRPEAAY
The following text describes a protein:
Function:
Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Has an essential role in mediating growth by negatively regulating insulin signaling. It also has a role in maintaining presynaptic function in the neuromuscular junction synapses of third-instar larvae.
Sequence:
MCGVFDFKDMEGSSGYGGNNCNDVGTSDEGCESHSTEEQHREAALRMQDSDANSESAAEMSSEGEIGSQSEDYSGHHDQGDAHWEPQEALTFNTSLASAHTYLGGLGDLEDVVSDGFNGAGGQVLKLPMFYLEGIVLFPHQKLPLRVLQQRFKAAVTHALCPDSNDAFQTLGVIHIRVSRRGIHVANYGTTAKICKVKEQRDGSVNVMTTGEQRFRILTVWTRPDGALFAQVQIIEEDTKKLGDFPGRFNHAFSPMASVFKRRTGRAKHSPTGLLSGYAPRAASEDEFFEEPEDAEPNVNYHADIREGQMAQGDHVLQEESEVEDEVADEYRIEALNGDESDDFVDAVAGDGDCSDEDYDGTGSFFERPPVRQRLDFESSIARRLEEMESVEREPTEGRNRKPPEPLEVSQYREKGFPLEGEQSTEEVGDKERQPAQSEESTAAETLPLCAVGSRGGPYVNAYRKWRKDASRWSMRAQLSTWPHWVYRQYDAFDLARRAADMMRQMGNHPRLEELVTKPTELSYYIGSNMPIQDHTRQELLEIDTTLARLKREIQLLEGLDTLRCNCCREVIGRRRDVFVMSTEGAIGAYVNAHGYIHETLTMSCARNMRIKGAPQTENSWFPGYAWILAKCQTCYLNNREQHMGWRFIAEDPNTRPQTFWGIRRTQLISSSESRAPDTN
The following text describes a protein:
Function:
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Sequence:
MNELLIKNVNIIDWCQNFHGDVYIKNGIIEELGKDLNKNCEIFDGRGLTLLPSFIDMHAHFRDPGFTYKEDILTGSRAAVKGGYTMVNLMANTKPICSSNKEVEYVLEKGKEIGLVDIHQCMSITKDFSGDDISHLDSIDKKVKIISEDGKDVMNTRVLIEAMFKAKEKDLIVMCHSEEHDVTNLDTRLSENLMTWRNIALSEFTDCKVHIAHVSTKESMEYIKNAKKKGLKVTCEVAPHHIALTNKIFYRVNPPLREEEDIKVLIEAIKEDLVDCIGTDHAPHSKEDKLKGSPGISGIETSFSTCYTKLVHNNHISLSKLSKIMSKNPADILGVNNGEIKIGREADLVLVDTKEEYKVKSEEFHSKGKNTPMDGMYLKGRIKVTFKAGCIVYSEF
The following text describes a protein:
Function:
The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MKNILQWSPPEGLQGAEVTYTVRYFIYGQKKWLSKSECRNILRTYCNLSAETSDYEHQYYARVKAVWGTNCSKGAQTGRFYPFLETRIGPPEVALTTDKKSISIVLTAPEKWKKDPEESSISMQQIYSNLKYHVSIYNAKANKTWSQCVTNQMLVLSWLEPDTLYCVHVASFVPGPPRLAQPSEKQCVSTLKDPASALKVKILFWYVLPASVTVLLFSVMGYSLYRYTHVSKEKHPANLILIYGNEFDKRFFVPAEKIVINFITLSVLEDAKISLKDVRVMEKSNDASALREPSEDWEPQQEEVEVKHLGYSSHLMGVLFDSEETARGTSLPQQEPLGRTTATDPAVAEYEYSLRPADICVGPADQELNLQEEGPRRGQLFERQAASADAGPQTLLYSYAPQLRDLDHLPQEHVDREQGPEEQPATTLADWDPRTGRLCIPSIPSFEHDPEGRERPEHGELLEDGLLSRLYADQAPDGPPKESEAYLTQFMEEWGLCVHVEDS
The following text describes a protein:
Function:
Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
Subcellular Localization:
Nucleus. Mitochondrion.
Sequence:
MRASRIAKETSRLFEGTTAAMATPATPRRSTRLSTLARFAYEANNANANASSSSAPVDLRSSPLRATKLEEDHEEDETGVTFGSDIEDAVKSSGLPSPKVKRRNPIGTRKRKRITTTTTTTVLKKEESLPAPTRIKTERRSTRIINQAAEAEVKSDSEIDINDIPVAGTSTTSSRKRTTRKPARKTTDAVTGEVKVEPPSDWEEVYNLVKEMRISGPAANAAVDSMGCERLASNNASARDRRFHTLVALMLSSQTKDTVNAEAMLRLKKELPPHAEGAEPGLNLENMLAVEPAVLNELIGKVGFHNNKTRYLKQAAEILRDRYNSDIPDTIEGLMSLPGVGPKMAHLCMSADNGWNRVEGIGVDVHVHRITNLWGWQNPPTKTPEETRLALQSWLPRDKWKEINWLLVGFGQSVCLPVGRKCGDCELGLRGLCKAAERKKVTEGRKRRAVVKEEKAEVDTEVVRFKREPKEEGDNEEDERDMVVKREKREARIEIKEEEEARVRELVVNEPVPPVIQEAVADEAVKMESIEDVEMEDVDEVQSTIEHSPPIIKQEGMRVKRERLADAEEDSEEADQTSGVKEEVLRVKQEQSVHDMGAGEEEENRLPHIVKRQHVRIKQESNIHGEQVESAHRRRIMKREPGRDLATVKQEPGFDEEKADDLQPQAVKPEHPSVKQESYIPEQTKEENHRSSTVKRESFNGAAIVKPEPNLNNEDAEGHQARARIVKREPLLGRTMVKQEPNLGDPEGREGQNGPTIVKREVGQLKQEAEDEQGEDEEVDEPVVKSETVERQQEPVRVKREAAGEGEEEEDGYVKTEHGGRVKVEDGMARIKLER
The following text describes a protein:
Function:
May act as a GTPase-activating protein for Rab family protein(s).
Sequence:
MWVNPEEVLLANALWITERANPYFILQRRKGHAGDGGGGGGLAGLLVGTLDVVLDSSARVAPYRILYQTPDSLVYWTIACGGSRKEITEHWEWLEQNLLQTLSIFENENDITTFVRGKIQGIIAEYNKINDVKEDDDTEKFKEAIVKFHRLFGMPEEEKLVNYYSCSYWKGKVPRQGWMYLSINHLCFYSFLMGREAKLVIRWVDITQLEKNATLLLPDVIKVSTRSSEHFFSVFLNINETFKLMEQLANIAMRQLLDNEGFEQDRSLPKLKRKSPKKVSALKRDLDARAKSERYRALFRLPKDEKLDGHTDCTLWTPFNKMHILGQMFVSTNYICFTSKEENLCSLIIPLREVTIVEKADSSSVLPSPLSISTRNRMTFLFANLKDRDFLVQRISDFLQQTTSKIYSDKEFAGSYNSSDDEVYSRPSSLVSSSPQRSTSSDADGERQFNLNGNSVPTATQTLMTMYRRRSPEEFNPKLAKEFLKEQAWKIHFAEYGQGICMYRTEKTRELVLKGIPESMRGELWLLLSGAINEKATHPGYYEDLVEKSMGKYNLATEEIERDLHRSLPEHPAFQNEMGIAALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAFWLLVALCERMLPDYYNTRVVGALVDQGVFEELARDYVPQLYDCMQDLGVISTISLSWFLTLFLSVMPFESAVVVVDCFFYEGIKVIFQLALAVLDANVDKLLNCKDDGEAMTVLGRYLDSVTNKDSTLPPIPHLHSLLSDDVEPYPEVDIFRLIRTSYEKFGTIRADLIEQMRFKQRLKVIQTLEDTTKRNVVRTIVTETSFTIDELEELYALFKAEHLTSCYWGGSSNALDRHDPSLPYLEQYRIDFEQFKGMFALLFPWACGTHSDVLASRLFQLLDENGDSLINFREFVSGLSAACHGDLTEKLKLLYKMHVLPEPSSDQDEPDSAFEATQYFFEDITPECTHVVGLDSRSKQGADDGFVTVSLKPDKGKRANSQENRNYLRLWTPENKSKSKNAKDLPKLNQGQFIELCKTMYNMFSEDPNEQELYHATAAVTSLLLEIGEVGKLFVAQPAKEGGSGGSGPSCHQGIPGVLFPKKGPGQPYVVESVEPLPASLAPDSEEHSLGGQMEDIKLEDSSPRDNGACSSMLISDDDTKDDSSMSSYSVLSAGSHEEDKLHCEDIGEDTVLVRSGQGTAALPRSTSLDRDWAITFEQFLASLLTEPALVKYFDKPVCMMARITSAKNIRMMGKPLTSASDYEISAMSG
The following text describes a protein:
Function:
Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MVLNENDKEFVKKLFDSLDKDNNGKLTREEIKEGFFKLRIPSSEKDIESFLTNVDKDKDGSVSFKEFEDFTIENIKKLKIVFEELDTNKSGTLDIHEIEESIKKLNIPLYSEQELIRLFHRIDKNRDNQIDFNEWRELLVLLPNSNLQLIISFWKDSQILDAGFDNGGFIPPMVEKKEKASSLRNTITYMLAGSVAGFASRTSTAPLERVKIMCQLNHGKPISLISAFKACYKDGGIKGFFRGNLANIIKVSPESAVKFGTYEYVKKLFAENDCELTSAQRFISGSVAGVVSHTTLFPLEVVRLRLSAEIAGTYNGIFDCFKKIAISEKSIRPFYRGLGASITATIPHSGVNMMVYEFLKHKVIKMTGNEFPTAGQLLVCASTSSVCGQLVGYPFHVVKSRLITQGSSVNQEKYTGLFDGLTKIIKKEGPIGLYKGIVPSFMKSIPSHSITFIVYEGFKKAFDVNLKEKKHH
The following text describes a protein:
Function:
Adhesion molecule that promotes lamina-specific synaptic connections in the retina. Expressed in specific subsets of interneurons and retinal ganglion cells (RGCs) and promotes synaptic connectivity via homophilic interactions.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Synapse.
Domain:
The PDZ-binding motif mediates interaction with PDZ domain-containing proteins and is required for is required for synaptic localization in photoreceptors.
Sequence:
MKGLGVPAAALLWGGLSALLPPSLPADDVSPYFKTEPVRSQVHLEGNRLVLTCMAEGSWPLEFKWLHNSRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEDSETQQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKISPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVANVGGPADPIAPTIIVPPRNTSVVAGTSEVTMECVANARPLIKLHIIWKKDGVPISSGISDYSRRLTILNPTLGDSGYYECEAVLRSSSVPAVAEGAYLSVLEPPQFVKEPERHITAEMEKVVAIPCQAKGVPPPDMAWYKDASLIHPEQLSRFQLLADGSLQISGLLPDDTGMFQCFARNAAGEVQTTTYLAVTSIAPNITRGPQDSTVIDGMSVILNCETSGAPRPAITWQKGERILASGSVQLPRFTLLESGSLLVSPAHLTDAGTYTCLATNSRGVDEASADLVVWARTRITDPPQDQSVIKGTKASMSCGVTHDPSVDVRYIWEKDGAPLGTESGPRLRLDETGTLHISQTWSGDIGTYTCKVLSAGGNDSRSAHLRVRQLPHAPESPVAVLSPLEKRAINLTWAKPFDGNSPLLRYLVEISENNAPWTVLLASVDPELTWVVVRGLVPARSYQFRLCAVNDVGRSQFSKDTERVSLPEEPPFAPPQNVIASGRTNQSIMIQWQPPPESHQNGVLKGYIIRYCLAGLPVGYQFKNITNADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSMKVTEWTLQGVPTVPPGNVQTEATNSTTIRFTWNPPSPQFINGINQGYKLIAWEPEHEEEATVVTVRPNFQDSVHVGYVVGLKKFTEYLTSVLCFTTPGDGPRSPPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPLEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSSSTISSGVPPELPGAPTNLGISNIGPRSVTLQFRPGYDGKTSISRWQVEAQVGQNGEAEEWGLVHQLANEPDARSLEVPNLNPYTYYSFRMRQVNIVGTSPPSLPSRRIQTLQAPPDVAPANVTLRTASETSLWLRWMPLLEQEYNGNPDSVGYRIRYLRSDGQGRAVVHVIHDRVEREYTIEDLEEWTEYRVQVQAFNAIGSGPWSHLVLGRTRESVPSSGPSNVSAQATSSSNMLVRWSDIPEADCNGLILGYKVMFKEKDSEARAQFWLAEGNTSRSAQLTGLGKFMLYEIRVLAFTRIGDGVPSRPPILERTLDDVPGPPVGMLFPEVRTTSVRLIWQPPTAPNGIILAYQLTHRLNTTTANAAVSEVLGPSTRQYTATGLQPEATYLFSITAQTRKGWGEAAEALVVTTEKRDRPQPPSKPLVRQEDVRARSVLLSWEPGSDGLSPVRFYTVQTRELPSGEWALHPASISHNATAFVVDRLKPFTSYKFRVKATNDIGDSEYSEESESLTTLQAAPEEAPTILSVTPHTTTSVLIRWQPPSEDKINGILLGFRLRYRELLYDSLRGFTLHGIGNPGATWAELTPVYAVHNLSEVSLTQYELDNLSKHRRYEIRMSVYNAVGEGPPSPPQEVFVGEAMPTGAPQNVAVKAATATQLDVTWEPPPTESQNGDIQGYKIHFWEAQRQNESARVKTLFLPETGVKLKNLTGYTSYWVSIAAFNAAGDGPRSTPVTARTQQAAPSAPGSIRFSELTTTSVNVSWEPPPLPNGILEGYRLVYEPCMPVDGVSKIVTVDVKGNSPLWMKVKDLAEGITYRFRIRAKTFAYGPDVEANITTGPGEGAPGPPGEPFISRYGSAITIHWTSGDPGQGPITRYVIEARPSDEGLWDILIKDIPKEVTSYTFSMDILKQGVSYDFRVIAVNDYGYGTPSTPSPSVSAQKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKSDSGNGSKANALTHGEMVSLDESSFPALELNNRRLSVKNSFCRKNGIYTRSPPRPSPGSLHYSDEDVTKYNDLIPAESSSLTEKPSEVSDSQGSDSEYEVDPAHQKAHSFVNHYISDPTYYNSWRRQQKGISRAQAYSYTESDSGEPDHTPLSNSTSTQQGSLFRPKASRIPTPQTPGNPPSQPGTLYRPPSSLAPGSRAPIGGFSSFV
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
METPEECLLLEDLSQVMIQSNSNTELVDAEGDSTLNTPPPENGDADGVPLLGLDLVTQCNSSSQEDNSDDGLIPQFMDCIKVLEKENEILVPMVSSHVDKYLKAMLDSESKPELSPPPPELYPDVNMVVDALPSGIVTRLSDTAKQMMEAGFERECCEAYSKWRREFQEQCLSALGLKLQELKIEDFENWIKTCKAAVKIMFPNERRLSNIVFSGFHRAADVSFTEVCMKLTICLVSFADTIITTTTTTTDQSYLLPSFLSSVIPEMSKSLHELNQESLLHGFCKDGILLEADVKKVHERFEIFKAFANLIYINTAQETVAGGGGLHLITQQATNYIDHVCESFGETVREYKVIPGREGKSSFSELLARMIELLESILETKSRDDYTDPALGYVFMMNNLWYIGQEACKWRSLVDGRTILDDHWFQQNTTKVEQNCKLYQRSSWNKMLDILKLEGNESVAPPNVVAESMKDKLNLFNLQFEKIYFFQSTWILSDHKQLREQVINSIDSTLLPAYGKFIDRFQDVLGEHACEYIEYGIVDIQNRLSCLFLLSE
The following text describes a protein:
Function:
Involved in metal ions homeostasis, including iron ions (Fe) acquisition, via the regulation of NAS4 and NAS2 genes expression. Necessary for plant survival in alkaline soil where iron availability is greatly restricted. Triggers tolerance to nickel (Ni) and zinc (Zn) ions.
Subcellular Localization:
Nucleus.
Sequence:
MGNRRAPCCDKSQVKRGPWSDEESERLRSFILKNGHQNWRSLPKLAGLMRCGKSCRLRWINYLRPGLKRGNFTKEEEDTIIHLHQAYGNKWSKIASNFPGRTDNEIKNVWNTHLKKRLVKRSISSSSSDVTNHSVSSTSSSSSSISSVLQDVIIKSERPNQEEEFGEILVEQMACGFEVDAPQSLECLFDDSQVPPPISKPDSLQTHGKSSDHEFWSRLIEPGFDDYNEWLIFLDNQTC