lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
Sequence:
MPVSQHGGKVGHRSTSSCLTRDHQRTPCCPFRRRDGFPCCAGALAASPSSPSPPPSARSSMTTAPDRSAPARTDKTTQHFDENAQHIAKRQYLQGNDGDISGMFWRIADWVAGAEAPEARQGWAQQYYDLMAEKKFCPGGRVLAGAGTQHGNVLNCFVQGATEHDPSSFEGVMEVAKKLALVTKVGGGNGVNLDVYRPRAQSSRSDNGVRGWVYMSAEHADVQDFIEGLMRPPTQPDGEKQPVSVRNWTRVVYGQAISPELVASARANGVQIVRTLPEGVTAVADDMGGIIDAARQVAEIAKLNIEPRIDLSAMRPEGAPIKGSGGTSSGPVSFLMEIFDNFIEWANRGAEDSGPINTLRYVYAPVLRVVRQGGTRRGAGMATISIGHPDVLDFLTAKDLDREAAEGDISTFNISILVDTKFWDTLQADGVWTIDAQDVPGKYFPVPQEGEYAGTFPELPTRAEDGAKGVPVYGSGIPARWLWDQIAQHAWSTGEPGLIFNDRVNEYSALKNLGERYEIRSTNPCVTADTWVSTAFGARQVQDLIGKDFCATVNGESFSARGGFWLTGVKSVLKVTTRRGYELRLTGNHQLLKVTHQTRKVQQTAWVETATLAAGDRIMLNDHRTVKPWAGAGNFSEGWLLGSLIGDGTFLTDKARPMAALGFWGEERQAQADSAQARLSKLGAVKKLWRSNDEQRQRVRLSSEALAELGAKYGVVHGHKTLTDKVEQGGYEFYRGVLQGLFDADGSVQGTQSKGVSVRLAQSDLSLLKRAQRMLSRLGIMSSLYAERRLAGTSTLPDGKGGSAEYPTQAQHELIISGSNLAVFAERVGFSEAGKAARLAEKLAGYARNLNRERFSDEIVSIVPDGEEAVYDVTVEQVHAFDANGVLAHNCGEIPLTVGEPCDLGAINLAAYVRGSDFDFAAFRADVRTCVRFLDDVLDVNVFALEDNRVASQDLRRLGLGVMGLADALIKMGLRYDNESGRQAIYDIMSALREEAVAESERLGQERGFYPVYERNREQVPHDPRRNVAVLTVAPTGTTSMLMGVSSGIEPVFSPFIWRKIGSEYRALLAPLFVELLESYPAPKGMEKDGGWDWDKVTEAVSENHGSVVGLSFIPDALQQVFVCAHDISPVDHVRMQGTVQRAFDDGGQLAANSLSKTINLPNSASVDDVKSAYEEAYRTGCKGITVYRDGSRQFQVLSTSKKKAKTEERGSAEPLADSKPAEAPAVTAPVSAPAAAAQPQPHYERPGRLHGITDMVKLTDPTSGHRRSFLVTVNHLNGNPVEVMVISGRAGDEANADSEALGRVVSIALQHGVPASALIHTLRGINGGLYGSYNGRLVGSKADLIAVALDTFQKDMAAAPLPPLAGGSGEVAPSAPASTGVSVDGLGQERCPVCEEKAVIREEGCLKCQACGYSKCG
The following text describes a protein:
Function:
Involved in the degradation of beta-alanine. BauR activates the transcription of the bauABCD operon.
Sequence:
MAKSRNPSLGQVSDFDIRLLRIFKTIVECGSFSAAESTLGLSRSAISLHMGDLEKRLGMRLCQRGRAGFALTDEGREVYRATQTLLAALEGFRAEVNDLHQHLRGELNIGIINNLVTLPQMRITHALSALKGQGPQVRINIGMTTPNEIELGVLDGHLHVGVVPLISPLSGLEYLPLYDEHAQLYCSRGHALFERADGDIAVDEVLAADAVAPSYRLPAEAQARHQELNNSASASDREGMAFLILTGNFIGYLPSHYAADWVAAGMLRPLLPERFHYAIALTIVTRKGRRPNLVLERFLEAVAVS
The following text describes a protein:
Function:
Activates endogenous long-chain fatty acids (LCFA) by esterification of the fatty acids into metabolically active CoA-thioesters for subsequent degradation or incorporation into phospholipids. Acts preferentially on C16 and C18 fatty acids with a cis-double bond at C-9-C-10.
Miscellaneous:
MISCELLANEOUS: Present with 6440 molecules/cell in log phase SD medium.
Subcellular Localization:
Cell membrane.
Domain:
The FACS motif is required for catalytic activity and substrate specificity.
Sequence:
MSEQHSVAVGKAANEHETAPRRNVRVKKRPLIRPLNSSASTLYEFALECFNKGGKRDGMAWRDVIEIHETKKTIVRKVDGKDKSIEKTWLYYEMSPYKMMTYQELIWVMHDMGRGLAKIGIKPNGEHKFHIFASTSHKWMKIFLGCISQGIPVVTAYDTLGESGLIHSMVETESAAIFTDNQLLAKMIVPLQSAKDIKFLIHNEPIDPNDRRQNGKLYKAAKDAINKIREVRPDIKIYSFEEVVKIGKKSKDEVKLHPPEPKDLACIMYTSGSISAPKGVVLTHYNIVSGIAGVGHNVFGWIGSTDRVLSFLPLAHIFELVFEFEAFYWNGILGYGSVKTLTNTSTRNCKGDLVEFKPTIMIGVAAVWETVRKAILEKISDLTPVLQKIFWSAYSMKEKSVPCTGFLSRMVFKKVRQATGGHLKYIMNGGSAISIDAQKFFSIVLCPMIIGYGLTETVANACVLEPDHFEYGIVGDLVGSVTAKLVDVKDLGYYAKNNQGELLLKGAPVCSEYYKNPIETAVSFTYDGWFRTGDIVEWTPKGQLKIIDRRKNLVKTLNGEYIALEKLESVYRSNSYVKNICVYADESRVKPVGIVVPNPGPLSKFAVKLRIMKKGEDIENYIHDKALRNAVFKEMIATAKSQGLVGIELLCGIVFFDEEWTPENGFVTSAQKLKRREILAAVKSEVERVYKENS
The following text describes a protein:
Function:
Essential for the formation and stability of microtubules (MTs). Required for the organization of the mitotic spindle and for the proper attachment of kinetochores to MTs. Promotes the recruitment of NUDC to the mitotic spindle for mitotic progression.
Subcellular Localization:
Cytoplasm, cytoskeleton, spindle. Midbody.
Sequence:
MEETQPSGEFCTTAKWENRLQTQEEEIMLLKSTLCDVLRRICVLEHQIPPETQGDTSLKVQQIADISKSSQVNRNDVGTQTEWAVEHTGSIESIDTGEGPGVFENESLNGGATDGIGDSDGPREFEQLPQSQGPDEAVAHARTVHALKQTRNEFFRRSSTSDKLVKDAKDKGKKLEKKSASSANLLGSSGSRRSNYNLEGLTVKVFLRGRPITMYIPSNMQNHDDHKPELPSEKLQLEWVYGCRGRDSRCTLRMLQSGEVIYFTACVIVICDVSRGTQRHFLRHTDCVRCLAVHPDGVRVASGQTAGVDKDGKPMVYIWDSCTLQILHQIGLGFFERGVGCLAFSTADSGSFLCVVDDCNDHVLSVWDTARGNKIAETKSTNEPVLCVAFNPVESSNIVTVGKSHVHFWTWSGTSLTKKQGIFGKYKKPRYVQCLLFDRTGDVLTGDSEGQILTWGRSAADTRTLGKGAKDTYQIVRHTRAHEGSVSTLTALRGGLVLSTGGKDRRVVLWSETLSQLKECEIPEHFGTVRSVAEGLGGELLVGTTKNALLKGSLELGFTHVIQGHTDELWGLATHPSQNMFLTCGHDKQFCLWNGTEHTLSWGCVLEDPGLCADFHPNGREVCVGLSTGRWVVLDIQSRCTLYIHSDGNEQLSVVRYSTDGTYLAIGSHDNVIYIYSTGQKDHRVERECSRESYMEEKDCQEEGDSPRGEGDSITSDRVHRYTRYGKCVGHSSFITHLDWSRDGKYIMSNSGDYEILYWDIAGGCKLIRNRYESKDREWATYTCVLGYHVFGVWPEGSDGTDINALSRSRGMTLVSVADDFCKVHLFRYPCNKPKAPSHVYSGHGSHVTNVRFTHDDSHLISLGGKDASIFQWRVVGGGYLPRSHSLSSSSLEAAQ
The following text describes a protein:
Function:
An odorant receptor which affects chemotaxis to the volatile odorant diacetyl. Specifies AWA neuronal cell fate via the odr-7 pathway.
Subcellular Localization:
Cell projection, cilium membrane; Multi-pass membrane protein.
Sequence:
MSFAWISIQNRIQHFSTIISFFLNSVMIYLIVIFSPKKIGTYKYLMIYISFFQMFYSIMDVISLPVYHTVSSVFVVFKDIHEEDYIPVWVHYWLLVVYTGCYGFCMGIFGIHFFYRFLAIYGHSKILKTFDTWKLFLWLLIPPIFAFIWAITVGICFAPTPETSLEIQQSILESYDLKIDQIVYIAAFIWPKNPGTGRKQLNLRPAIGIGIEELIVVSSLSAIFYFGSRCYYKIQEHMKVAISVSKITKNLHRQLFYALVMQTVIPLLLLHIPVSGLFMFPILDSDLGFLTGFVTITIAIYPAIDPLPTMFIIENYRKAIFGFF
The following text describes a protein:
Function:
Member of the two-component regulatory system RstB/RstA. RstB functions as a membrane-associated protein kinase that phosphorylates RstA (Probable).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MKKLFIQFYLLLFVCFLVMSLLVGLVYKFTAERAGKQSLDDLMNSSLYLMRSELREIPPHDWGKTLKEMDLNLSFDLRVEPLSKYHLDDISMHRLRGGEIVALDDQYTFLQRIPRSHYVLAVGPVPYLYYLHQMRLLDIALIAFIAISLAFPVFIWMRPHWQDMLKLEAAAQRFGDGHLNERIHFDEGSSFERLGVAFNQMADNINALIASKKQLIDGIAHELRTPLVRLRYRLEMSDNLSAAESQALNRDISQLEALIEELLTYARLDRPQNELHLSEPDLPLWLSTHLADIQAVTPDKTVRIKTLVQGHYAALDMRLMERVLDNLLNNALRYCHSTVETSLLLSGNRATLIVEDDGPGIAPENREHIFEPFVRLDPSRDRSTGGCGLGLAIVHSIALAMGGTVNCDTSELGGARFSFSWPLWHNIPQFTSA
The following text describes a protein:
Function:
Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP, which cleaves pre-rRNA sequences.
Subcellular Localization:
Nucleus.
Sequence:
MVRIKHRYILFEILYPPTADTRVTPREDFNQFSQSESNALLTLHQSSPNSINVKTILNVIRKSLSDHYGDVGAGKAGMLLNVKYFSNRTSTGILRCGRDQSDYIIGAMSLIEKMENNYVIIRCLHVSGTIKKCEEYSIERTKQLINVIKNKSKGKVDEYISQMNEINHVEEDEEEEQEEENQDDVRISKS
The following text describes a protein:
Function:
Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions.
Miscellaneous:
MISCELLANEOUS: Present with 5530 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MTKKDKKAKGPKMSTITTKSGESLKVFEDLHDFETYLKGETEDQEFDHVHCQLKYYPPFVLHDAHDDPEKIKETANSHSKKFVRHLHQHVEKHLLKDIKTAINKPELKFHDKKKQESFDRIVWNYGEETELNAKKFKVSVEVVCKHDGAMVDVDYKTEPLQPLI
The following text describes a protein:
Function:
Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
Sequence:
MSSEDLSADDLTLPVKRVTGDSLEDRLTANAYHNILPARYLRKDTDGEHVESQEDLFERVAKNIALAEVVFESDDPVTATPSQLKPDHPRRDELAAEVFGSDVDPDSETATVELTDSNINKFAYDTVVPELDDPEVREHVEGVAAEFQDLMASLSFMPNSPTLMNAGDELQQLSACFVDSPDDDITDIHQTAKEAAEVFQSGGGMGYAFWQLRPYGDTVGSTGGIASGPLTFMETFDQMCETIAQGGARRGAQMAVMRVSHPDVVEFIHAKNKDVSLAQTLKLNDPDDYTYTEFSEALEEARDLIDEDGRVPEHLRNAVEGHLSNFNISVGVTDGFMEALEAGEEYTFTNPRTGEAHIATEETKEMYSRYGLGHYVTPGEELTLPAEELWSRIVEGAHENGEPGVIYLERVNDEHSFDVEEHPDHRILATNPCGEQPLEEYEACNLGHINLSTLAAQDAPDWRVWSQTHDFDTLEAGVSRFLDEAMDTDAFQRRIEMGTRFLENVVTMSDFPVPEIEQKVSEMRKIGLGVMGLAQLYIQLGVKYGSEEGNEIASQLMQTINHDSKTASHELALERGSFDEWDNSKFAAPTEYADWFEHHTGEDAADWADGYPIRNHNTTTIAPTGTTSMVGNTTGGCEPIYNVAYYKNVSDDVQGDEMLVEFDDYFLRTLEDNDIDVQAVKEEAQTQMANNDFDGVDGLTTVPDAIGELFVVTSDLSGKDHAAVQTACQNGVDSAISKTCNFPNDASVEDMDEVYRYIYDNGGKGVTVYRDGTRSKQVLTTRADNTEFSGLDEEEAAAAMVDTIQETFGGIEGFLENDDIQDAFGADLRELFATGDDAAFDEEDFAEKQPRPDLLHGVTQRVDTGYGKLYVTINENPERERPFELFANTGNSGGFTGSFTEALAKTISVALRSGVDPDEIADKLQGIRSPKVAWDKGEQVNSIPDAFGTALRRYLNGDVDRAAYPQQQHLTEIDADDAAHHETDGGAAESLGGPQGPTGAGESADAQQQSQDATQSLIDAGESPECPECGAMTLYYSEGCKTCESCGWSEC
The following text describes a protein:
Function:
Involved in mRNA splicing and cell cycle control.
Subcellular Localization:
Nucleus.
Sequence:
MVVLKGGAWKNTEDEILKAAVSKYGKNQWARISSLLVRKTPKQCKARWYEWIDPSIKKTEWSREEDEKLLHLAKLLPTQWRTIAPIVGRTATQCLERYQKLLDDLEAKENEQLGLISGEGAEAAAPVNDPNSRLRFGEAEPNLETLPALPDAIDMDEDEKEMLSEARARLANTQGKKAKRKDREKQLELTRRLSHLQKRRELKAAGINIKLFRRKKNEMDYNASIPFEKKPAIGFYDTSEEDRQNFREKREADQKIIENGIRNNEMESEGRKFGHFEKPKPIDRVKKPNKDAQEEKMRRLAEAEQMSKRRKLNLPSPTVSQDELDKVVKLGFAGDRARAMTDTTPDANYSTNLLGKYTQIERATPLRTPISGELEGREDSVTIEVRNQLMRNREQSSLLGQESIPLQPGGTGYTGVTPSHAANGSALAAPQATPFRTPRDTFSINAAAERAGRLASERENKIRLKALRELLAKLPKPKNDYELMEPRFADETDVEATVGVLEEDATDRERRIQERIAEKERLAKARRSQVIQRDLIRPSVTQPEKWKRSLENEDPTANVLLKEMIALISSDAINYPFGNSKVKGTANKVPDLSNEEIERCRLLLKKEIGQLESDDYIQFEKEFLETYSALHNTSSLLPGLVIYEEDDEDVEAAEKFYTNDIQRDLAKKALECNKLENRVYDLVRSSYEQRNFLIKKISHAWKALQTERKNLTCYEFLYNQERLALPNRLEAAEIELSKMQQIEAYAQQDYARVTGQN
The following text describes a protein:
Function:
Positive regulator of abscisic acid (ABA)-mediated signaling pathways involved in abiotic stress responses (e.g. osmotic stress) and leading to various plant adaptation (e.g. stomata closure).
Subcellular Localization:
Cell membrane. Cytoplasm, cytoskeleton. Note=Associated to the cytoskeleton in hypocotyl and cotyledon cells, but not in root cells, where observed as disconnected cytoplasmic speckles. Localized to the plasma membrane in the epidermal cells of cotyledons and roots, including root hairs.
Sequence:
MKKHKFRETLKSFFEPHFDHEKGEMLKGTKTEIDEKVNKILGMVESGDVNEDESNRQVVADLVKEFYSEYQSLYRQYDDLTGEIRKKVNGKGESSSSSSSDSDSDHSSKRKVKRNGNGKVEKDVELVTGALKQQIEAANLEIADLKGKLTTTVEEKEAVDSELELALMKLKESEEISSKLKLETEKLEDEKSIALSDNRELHQKLEVAGKTETDLNQKLEDIKKERDELQTERDNGIKRFQEAEKVAEDWKTTSDQLKDETSNLKQQLEASEQRVSELTSGMNSAEEENKSLSLKVSEISDVIQQGQTTIQELISELGEMKEKYKEKESEHSSLVELHKTHERESSSQVKELEAHIESSEKLVADFTQSLNNAEEEKKLLSQKIAELSNEIQEAQNTMQELMSESGQLKESHSVKERELFSLRDIHEIHQRDSSTRASELEAQLESSKQQVSDLSASLKAAEEENKAISSKNVETMNKLEQTQNTIQELMAELGKLKDSHREKESELSSLVEVHETHQRDSSIHVKELEEQVESSKKLVAELNQTLNNAEEEKKVLSQKIAELSNEIKEAQNTIQELVSESGQLKESHSVKDRDLFSLRDIHETHQRESSTRVSELEAQLESSEQRISDLTVDLKDAEEENKAISSKNLEIMDKLEQAQNTIKELMDELGELKDRHKEKESELSSLVKSADQQVADMKQSLDNAEEEKKMLSQRILDISNEIQEAQKTIQEHMSESEQLKESHGVKERELTGLRDIHETHQRESSTRLSELETQLKLLEQRVVDLSASLNAAEEEKKSLSSMILEITDELKQAQSKVQELVTELAESKDTLTQKENELSSFVEVHEAHKRDSSSQVKELEARVESAEEQVKELNQNLNSSEEEKKILSQQISEMSIKIKRAESTIQELSSESERLKGSHAEKDNELFSLRDIHETHQRELSTQLRGLEAQLESSEHRVLELSESLKAAEEESRTMSTKISETSDELERTQIMVQELTADSSKLKEQLAEKESKLFLLTEKDSKSQVQIKELEATVATLELELESVRARIIDLETEIASKTTVVEQLEAQNREMVARISELEKTMEERGTELSALTQKLEDNDKQSSSSIETLTAEIDGLRAELDSMSVQKEEVEKQMVCKSEEASVKIKRLDDEVNGLRQQVASLDSQRAELEIQLEKKSEEISEYLSQITNLKEEIINKVKVHESILEEINGLSEKIKGRELELETLGKQRSELDEELRTKKEENVQMHDKINVASSEIMALTELINNLKNELDSLQVQKSETEAELEREKQEKSELSNQITDVQKALVEQEAAYNTLEEEHKQINELFKETEATLNKVTVDYKEAQRLLEERGKEVTSRDSTIGVHEETMESLRNELEMKGDEIETLMEKISNIEVKLRLSNQKLRVTEQVLTEKEEAFRKEEAKHLEEQALLEKNLTMTHETYRGMIKEIADKVNITVDGFQSMSEKLTEKQGRYEKTVMEASKILWTATNWVIERNHEKEKMNKEIEKKDEEIKKLGGKVREDEKEKEMMKETLMGLGEEKREAIRQLCVWIDHHRSRCEYLEEVLSKTVVARGQRRVSQRT
The following text describes a protein:
Function:
May function as a Ras GTPase-activating protein.
Sequence:
MMESLTVNENTINEFEIKNDIIIEQQQIQSKTSIPLLNIKDGNTTTTNTINEINNNNNNIETSTMSRKSLMTPSATYESLIRQQKTKDCNLTVKVFEARNLIEARLRKREMVKNGKSFKRAQNLLTEISSPNLMTFSDTTDPYCTVQLEKQKQRTRTIPKKLNPFWCEEFQLEISDPASAKLVLSVMDEKKYSNDEHIGKLVIPINTLKDQKERELWFPLTQPQSSKKVPQIQILFNFKPISLTDPSQPGHIQWKVLFGRNLSHSLATPLPSMSAASMGGSTSTENISNVYTNTTPFINWSVRSKKGDIVIDEEGIAWQDALTNGITRELKDSIECITFTLWRYEPKTFSDDGDISGLKSPRGTNSSASGSGFIPSTPPPSSHQKSNDTTATTTPSSTPSTPISPSSQSNNIKTPDSKTRSSSNASTNTPQTTPKSTGTSGGPAPPETINLSSSINSTSSLISNGSINVIDSSNNLHHHHNNGTNIMNPLKDGYEQYFIGQGIVLASHIDIEKPNDQWLCLYPKQTLDNKFGDIRLKLKYSEEVVLPLQSYQPLLELLQQENLYTITLLGKVTKHRESVSNNLIRVFEKTGKCLYLLKSLTDHEIDSTNNPDIIFRGNSLATKSVDLFMKLIGIPYLSQTIGPLIKKIYSSKKSCEIDPTKLEKGEDIKKNCKNLLSWVKKMTTAILSSVNNCPGPLREVFKSIQDKVVQRYPKDEITRYTAVSGFIFLRFFCPAILAPKLFDLMPDHPGIKTTRSLILIAKTLQNLANQVEFGEYKEDFMKDMNRFVIDNMENMKSFINTLSTVPADCPPGALQSPIILEKELACLYRHLIKQRQDMAEEMESTESEPKTQQEKDSFGKLIKILNSLDEDVQLASN
The following text describes a protein:
Function:
Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
Subcellular Localization:
Nucleus.
Sequence:
MARIAVDEEDLAQEFGTFDIKIQDEDVVDKLKELCMLYRLDASDMADEWMAFSISNNSASLTMDKLEQFERERANKTKTPKVKREKPAAVMHDISNINPDAEDDLLDVYSTPAAKGKNKRMLTTPENVSVVNKKLTSVSRSPVVPFSPGSFSPVNATPSQQYRSRSGAGETMVTFGEQRAKWKGQGAEGVAIQQYDRDNALTEKYKHMFYRVIDKSNVLNDLIEDMSSQLQQSHNMENLQHLAWPCQEPITVSGRVCCDMSTGRLNAHSVLLEGSRETSARKTVHLDLSEVSEYSLFPGQIVACDGLNTTGSKLVVSKFYQGVHLPFAEVDETSENLSVPVQVLVAAGPFTPSDSLAYEPLEDLLKYLKRDQPDVCVLMGPFVDSKHESIEKCTVEVPYDDMFKKIVLNLIKATEELETHLVFVPSQRDVHHEYVYPQPPFTVDGVNSPRVHFVSDPCTLTINGVVELASVLSLFQRVHFVSDPCTLTINGVRVHFVSDPCTLTINGVVELGEMFTHIHRVHFVSDPCTLTINGVRVHFVSDPCTLTINGVVELASVLSLFQRVHFVSDPCTLTINGVRVHFVSDPCTLTINGVGKMQEMTSHFGGGVICCFPFSRGSSDRLGRLIKHILTQQSYYPLYPPSEDVNIDYEHYEQFCRLQATPDVLIIPSDLRYFVKDVLGCVCVNPGRITKAQTGGTFARFVIQCPPSPTQGGAARKPRCTAAEVVRV
The following text describes a protein:
Function:
Acetylcholine receptor.
Subcellular Localization:
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Sequence:
MVICHSCTTFCILLVIDLVPCRIVGMENVENRVMFSLLDRSPQTNDTGPKPEKFEIAKGKFKVLEENSIGADTVSHLPTTREEHVSAVVPMPNFDPHRLEKALRTKGSIDGTEEALYRSLLDHTVYEKDVRPCIHHSQPTNVTFGFLLNQIVEMDERNQALTTRSWLNINWMDPRLSWNESLWSDIKAIYIPHARIWKPDIILVNNAIREYYASLVSTDVMVTSDGNVTWLFSALFRSSCPIRVRYYPFDDQQCDLKFASWSHDITEINLGLNTDKGDLSSYMNNSEFDLVDMTAVREVVRFPSDTNSDWPTIVIRIHMHRRPLFYVFNHIVPCVLISSMAVLGFLMPPETGEKINMIITTLLSMGVYLQSITESIPPTSEGVPLIGMYYVSSLLMVCLATCVNVITLNMHRNGAANQGRHVPAWMQKWILGYLATFMRMSIREPDSIALLKASQSKKSTIRRSSILRDLKRVKNMSNVRAKSKEQNANRECECMDPLVHIYAESIMTSLVSDPKPMNGSTIREDFASESTFLGRVVSDGIMPRISASSNSVLTEFETRFRRILKRVYRSLQQHEIREEILDERSRIQWQWQQLASVVDRLLLCLFCTATLFTIICLLIVPVVYRDNDVLSILNFF
The following text describes a protein:
Function:
The product of this enzyme, tetrahydrobiopterin (BH-4), is an essential cofactor for phenylalanine, tyrosine, and tryptophan hydroxylases.
Sequence:
MSKNILVLGGSGALGAEVVKFFKSKSWNTISIDFRENPNADHSFTIKDSGEEEIKSVIEKINSKSIKVDTFVCAAGGWSGGNASSDEFLKSVKGMIDMNLYSAFASAHIGAKLLNQGGLFVLTGASAALNRTSGMIAYGATKAATHHIIKDLASENGGLPAGSTSLGILPVTLDTPTNRKYMSDANFDDWTPLSEVAEKLFEWSTNSDSRPTNGSLVKFETKSKVTTWTNL
The following text describes a protein:
Function:
Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
Sequence:
MAAKKKVNDHPSLDIVSSHGVELTGKKIVLCVAGSVAAYKAIELARLLMRHGADVTCVASGAVTKLIQPDYFKWATGNDVITKLTGKLEHIKLADYNQSDLVIVYPATANTLGKLANGIDDTPISTVLTVGFGSKIPILMCLAMHESMYDNSAVKKNIEFLKNKIQFLSPQMIEGKAKAPEPEDVLDFVLKKFGFSSTLQNKKVLMTAGPTIEYIDPVRVITNLSSGKTGVLLASELISAGAKVTLIYGPGNEEPPKGAKIINVTTNKEMLDATKKELKKKYDIVIMAAAASDYTPEKPTKSKIKSNKKALTIRLKKAPKIIDQVKKSQKNTILVGFKAETNLSKSALIKSAKTKLKESNADIIIANDIGTKYQKNPNNNQIIIVDEKNTITSGWKKKEKIVKIIRKEIEKKIR
The following text describes a protein:
Function:
DNA-binding transcriptional repressor involved in response to toxic agents such as ribonucleotide reductase inhibitor, hydroxyurea (HU).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MNYLRDRFPPDNDQRPFRCEICSRGFHRLEHKKRHGRTHTGEKPHKCTVQGCPKSFSRSDELKRHLRTHTKGVQRRRIKSKGSRKTVVNTATAAPTTFNENTGVSLTGIGQSKVPPILISVAQNCDDVNIRNTGNNNGIVETQAPAILVPVINIPNDPHPIPSSLSTTSITSIASVYPSTSPFQYLKSGFPEDPASTPYVHSSGSSLALGELSSNSSIFSKSRRNLAAMSGPDSLSSSKNQSSASLLSQTSHPSKSFSRPPTDLSPLRRIMPSVNTGDMEISRTVSVSSSSSSLTSVTYDDTAAKDMGMGIFFDRPPVTQKACRSNHKYKVNAVSRGRQHERAQFHISGDDEDSNVHRQESRASNTSPNVSLPPIKSILRQIDNFNSAPSYFSK
The following text describes a protein:
Function:
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
Subcellular Localization:
Cytoplasm, cytoskeleton, spindle. Nucleus.
Sequence:
MEHGDLVFFPCLAVASIEDSGAQKQFCIPYLQSQSLMQLDRHTVYMIITNFMKTREEELKNLGADFTYGFIQVMDGEKDPRNLLVAFHIVQDIITKNYALGHFLEELFEVTSCYFPIDFTPPPNDPHGITREHLILGLRAVLASTSRFAEFLLPLLIEKMDSDVQSAKLDSLQTLSACCTVYGQKELKEFLSGLWSSIRREVFQTASEKIEAEGLAALQALSTCLSRSILSPDAEDLLDSFLNSVLQDCKHHLCEPDMKLVWPSAKLLQAAAGGSSRACWKVTANVLPLLLEQYNQHAQMALHTSASISKEKIHPPSSWLQYSCFAEQQTSNHRRTILEMTLGFLRLQSRWLDEEDENGLGSLKEALCSMVFSAVTDSSTQLHLVAVRILTALAMQQGFLSSRDTDLVVDHLTRLILQESDSESCMAAVEASGTLAKVHPSAFISRMLPQLCANLQTEPNDINLNESRVVSEHSVRRHCLEALAAVCTHQSILKETVPILLDYIRTAPNGEGETNAENVVSVCKSLYRVAVQCQEDSESLQFYHQTVLPCLLSLTVQAATQDSETSSHVLLKDDILTAMVPVISAACTHLKPELASKSVSQIVGLFLDGDVSLLPENNFSSKFQPFQVNGPTELQNRLVSLLMAFVCSLPRNTEIPHLRRLLQHLLLLSLAGCSPFAYSSASKCFAGLINKCPQGDLLDDILQVTTQRIDVGLADEPSRNQAITLLVWVTKALILRYHPLSGQLTDKMIGLLSDKQLGPSVANMFSLLVSDSPDVLNKACHADVRIMFRQRFFTENVPKLVQGFNSANGDDKPNYLKALSHVLNTLPKQVLMPELPSLLSLLLEALSCADEVVQLSTLTCLEPLLLEAPETLNVHIDGLISKLLRLTSSPAMAVRITSLKCIRALIKLPLHMLLPYKQQVIRALAKPLDDKKRLVRKEAVETRCQWFLLGSPGS
The following text describes a protein:
Function:
Putative Notch ligand involved in the mediation of Notch signaling.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MSPKLHIFLIFLLLLIPNSQSSGYLEIRLKSPFLLNATVTITEDIYFPTNKRVYNVPLVPDHTRILTNIPVKFHRPGTVLINSGPVDKFGLHYATIRSDRWNTKTMRIAPDEIQLPFTGFRIDVQCNRNWHGPYCDKFCNDDHARIINRRCTQNGTLGCPFMLSGPNCDIPLLQTECTLPCMNHGYCVSEFLNPLDTVDRSICECGVGFEGEQCEEKEYDYADAIEIEMHGIPRKYNLLKEFLNGSTVDNELRHLYH
The following text describes a protein:
Function:
NAD(+) hydrolase (NADase) that catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide. In addition to ADPR, also generates a cyclization variant of cyclic ADPR (cADPR), termed v-cADPR (probably 2'cADPR).
Domain:
The TIR domain mediates NAD(+) hydrolase (NADase) activity. Self-association of TIR domains is required for NADase activity.
Sequence:
MEDLEIFLKRFEDLLIDLATYNENESNDYIIYRKKLLSYDYLKDFIPDFIIKNRKPQFFRAYMQEIGGYKERRDLIYKGFERLYDYETIKNFDSDNSYNVNQIENFLERFEDLLIDLATENLKKDGFEEYSLFRKKFLTCNYFKDMPIFLKRNPKHFRYYMQSQGGYKERRKIISEEFNKLFSIIEGSNFNSDSNNKNKSINKKEYDIFVSHSSEDKEDFVKEFVNLLKQKGLSVWYDDDIVKIGHNLRKRISKGIKSSNYAVVIFSEDFFKSKWTNYEYDNIFLDFYDEEKVLPILHDLTIEDLEKFDGSIPLIRALSTKKFTVEEIIHEILERINEEKS
The following text describes a protein:
Function:
Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, CDP-glucose, GDP-glucose and GDP-mannose.
Subcellular Localization:
Cytoplasm.
Sequence:
MDDVKIISVNGLKESNFIRPRRLKYTQAGKDKIWDYMIVHDSVAILIFDVSIKSVVLVRQFRPAVYMTMCHYAEKTNDQPEPKPSDGITYELCAGIMDRKEPPQAIAASEVLEETGYEIEADKLQLISEYRNGVGTSGSLQFLYYAQVDNSMKVSEGGGCDEEGEMIDLYNLPLKDIKSFIEDTTVTNRPVGVLFALQWFLNNKAENFEQVD
The following text describes a protein:
Function:
May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding. Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I; The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Cytoplasm.
Sequence:
MGPASPAARGLSRRPGQPPLPLLLPLLLLLLPAQPAIGSLAGGSPGAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGAEDEEEEESFPQPVDDYFVEPPQAEEEEERVPPPSSHTLAVVSKVTPTPRPTDGVDIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADPPQAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVQTHLQVIEERVNQSLGLLDQNPHLAQELRPQIQELLHSEHLGPSELEAPAPGGSSEDKGGLQPPDSKDADTPMTLPKGSTEQDAASPEKEKMNPLEQYERKVNASVPRGFPFHSSEIQRDELAPAGTGVSREAVSGLLIMGAGGGSLIVLSMLLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP
The following text describes a protein:
Function:
Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
Sequence:
MADHDMLDNDEPLLVANSLSKSYGRIAACRDVSFSLYSGEVLAIVGESGSGKSTLLQLLSGQLAASGGHVTYRMRDGVTRDLATLGEAERRFLFRTDWGFVHQDPAQGLRMAVSAGANVGERLMAVGWNHYGRIRDTASDWLTRVEIDTARIDDAPRTYSGGMRQRLQIARNLVTEPRLVFMDEPTGGLDVSVQARLLDLLRSLVAELNLAVVIVTHDLAVARLLSHRVMVMKGGRVIETGLTDQVLDDPREPYTQLLVSSILPP
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSEPPQPPGKPSANAPKPAPRLKSIKPTTPGDANKITTPTIPSIKTKKEFKPNIPTARKKKDEKDPLSGAISDLISASLSPLAVVGDRPGKPNATSSGKFRSNLNPNRKKPAAIPITNLFQTPLVQAETQQPQSTYEMNKKNEKKDSDLLAQLFHEMEVDPMQPFHPTHLPLVDPRKIMKAYSLDDASKDLNETKRELEEKIKNGELSDTTNFTLNSIGSEDNNNNGGGSGQVKFVESSKKKNKEISTKDKPFYVEDQFLNKDKLFFIQLPNLLPSTQSKPNFNIPNPVLPPPKPTTITKTVTNPDGSITTTTIPINENTKIEDQPPPPPKELDEKAFVPVIYPGDFPPSIKEMPSGKLGTLKIYKSGKSILKIGTVEYDISSGDKLKFLEEVQCFQTKGGPDNSPTCYTLGIPSQHLVAAPIISQISGI
The following text describes a protein:
Function:
Transcription factor that may act during endoplasmic reticulum stress by activating unfolded protein response target genes. Activated in response to cAMP stimulation. Binds the cAMP response element (CRE). Activates transcription through box-B element and CRE. Seems to function synergistically with ATF6. In acute inflammatory response, may activate expression of acute phase response (APR) genes (By similarity). May be involved in growth suppression. Regulates FGF21 transcription (By similarity). Plays a crucial role in the regulation of triglyceride metabolism and is required for the maintenance of normal plasma triglyceride concentrations (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein; [Processed cyclic AMP-responsive element-binding protein 3-like protein 3]: Nucleus. Note=Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus.
Sequence:
MDGDISTGKMASPACAMAPLDSMEVLDLLFDGQDGILRNVDLAESWILTREEQKVLPNSDSDEFLNSILGPGDSDPSSPIWSPADSDSGISEDLPSDSQDTPPGSGPGSANVAARCHPSKQGEGPCPSYLPSTACPEPPRTQVHESSVAIDLDMWSTDTLYPEEQAGSPSRFNLTVKELLLSGGGGDLQQHPLAASQLLGPGSGHCQELVLTEDEKKLLAKEGVTLPTQLPLTKYEERVLKKIRRKIRNKQSAQESRKKKKEYIDGLENRMSACTAQNQELQRKVLHLEKQNLSLLEQLKHLQALVVQSTSKPAHAGTCIAVLLLSFVLIILPSISPFTANKVDSPGDFIPVRVFSRTLHNHAASRVAPDVTPGPEVPGPHKGSSGGLSADWGNFLEIPMLDDPTEELDNTTLVLANSTEDLGRATLLDWVASEPLLGQMGLEIPGEEIWLSWVPRWLRVRVVQDALGVL
The following text describes a protein:
Function:
Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML).
Sequence:
MFVQRRLSSSITRVIGWNFKNIRSKNDSLEVTFEEDGKPSKLIMPLAWLRDHCTSKTHYHYPTNQRKSNCTDLMNLSRIEGSDKISMDQNQKSLIIDWIDGHRSVFEIGDVVGKGRKKKGEKMDGVLKLWDSKTLGGVPRIEKSNLSLQSFSENLVKYGVVIIDGIEGTAEATEKLCQSLVPVHDTFFGQFWVFSNSATQDEPAYEDTAYGNEEIGPHTDGTYFNQTPGIQVFHCLTPANVGGDTVVVDSFHCAQILKNKHPEHFETLCNTKIAHHYLEGLRLAARSKVFNPYDRAPYSCLSSSESSASGAIKFYEAYQEFSRICHDHLNALTVSLRPGSVIFIDNFRVLHSRTAFQGYRKMCGCYLSRDNFMAKARPFFDGNVKEFL