lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Serine/threonine protein kinase that phosphorylates proteins on serine, threonine and tyrosine residues.
Sequence:
MLEGAKFNVLAVGNHHNNDNNYYAFTQEFYQKLNEGSNMSMESMQTSNAGGSVSMSVDNSSVGSSDALIGHPGLKPVRHYSLSVGQSVFRPGRVTHALNDDALAQALMDTRYPTEGLTNYDEWTIDLRKLNMGPAFAQGAFGKLYKGTYNGEDVAIKILERPENSPEKAQFMEQQFQQEVSMLANLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTRRQNRAVPLKLAVKQALDVARGMAYVHGRNFIHRDLKSDNLLISADKSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRAYNQKVDVYSFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPNDCLPVLSDIMTRCWDANPEVRPCFVEVVKLLEAAETEIMTTARKARFRCCLSQPMTID
The following text describes a protein:
Function:
Loads (host) replicative DNA helicase DnaB onto single-stranded (ss)DNA at the origin of replication (Probable). Reconfigures the DnaB hexameric ring, generating an opening large enough to permit ssDNA into the central channel. Necessary for the bidirectional replication of lambda DNA. It interacts with the ori (origin of replication) region of the genome during the initiation of replication.
Sequence:
MKNIAAQMVNFDREQMRRIANNMPEQYDEKPQVQQVAQIINGVFSQLLATFPASLANRDQNEVNEIRRQWVLAFRENGITTMEQVNAGMRVARRQNRPFLPSPGQFVAWCREEASVTAGLPNVSELVDMVYEYCRKRGLYPDAESYPWKSNAHYWLVTNLYQNMRANALTDAELRRKAADELVHMTARINRGEAIPEPVKQLPVMGGRPLNRAQALAKIAEIKAKFGLKGASV
The following text describes a protein:
Function:
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.
Subcellular Localization:
Nucleus.
Sequence:
MPGMTHSADRLRQSSGNFHWGLLPNWKEACRRRGPPSISPRCSAPTCGAPGLLSADPDRPLKGGGPLKSGGLPPAPAFKGPGCPDGSPVRLAGGWPNSAGRGAEPSRGRPNRRAGARRARGGRGRGSGSARGRMESLLQQLERFSEVLAVSRTAAVSAWGPAAVRRAVQWARYLRRAHGRLRAALEGRRRAGPRLGAWGGRDVVLSARLLGNRALGAAAHRCLLRLLFPGPAAPAPAPAAALQARLARLARRRGAVRLLLRGGPAEDAALRTQAELLLRRLRDGPAGGLLDGLWARAPRAAFLRAAAAALLLDPAGPAPGELLRWLLGRADALAALCRDLPAARLAALAARHPALRRAYLRQLARWGCRLRYDLPSGRWEAAEPAHVSWAELRGRFLSLARAPPPLKDAALAALEAWSARDGAFRVRGLSVWTDLLLALGPGAGTDSLGAAPSSGVLGAGGCRLARPGPARSPEHAHFPK
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MKSKISKVLGVCKKHKASTRNSCSLSKISGDLESITAAITTCHDDEKQHPGLDTFSRESETNEPAEMLVEDTSQSQGFAPWVDGSQSVENMENACNHMSNSDTIFSPVLNDELDGTGRDTDKINLDNHDLFLAFNRTRSYNVEPDDRAESEVAEDFDPQLFIKNQPELSDVVSNYWPRDTLRKKSVTLVLDLDDILDPDGKFISQRFYRDSCILLDGIYTKDLTVLGLDLAKVAIIDNCPQVYRLQINNGIPIKSWYDDPTDDGLITILPFLETLAVADDVRPIIGRRFGNKE
The following text describes a protein:
Function:
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Subcellular Localization:
Nucleus.
Sequence:
MLKFDKKQLRVVLNKLKNDKFLKSRSYVETQEDGKVTKQNYYYINYRTVANVIKYKLHHMHKRIETRERDSNNRPSFKCPTCGNTYSDLEVNQLIDPMFGTLNCVYCKTEVLEDKESASNQDARTSQARFNQQMEPLYKMLKEVENITLSQDILEPKPTLIPQLHPKYGMTRSAPKARASKPRSGEDWSSTRSDLNIDYKQEVIIDMGGGGKVEEEKKEMPRWLTESTVTGDSIQSYSNNGNEAPRLDDTDSKSTNNEVLQTLIVQERSKVTAAPSYHDNHDDASESDEFDDVTDDAVVMVAGKQYSYHEVANQGGALVELMTEAEKDEYIRIGQQVYEAMED
The following text describes a protein:
Function:
Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex.
Sequence:
MIFRFLGNNNSNELPDQQLLNEIGYLSNFEDEALEQLIENVFEFMIIQKAEDLMKSISDFSQQHSVNENTIKNIVRGCIVFFKGSAKNNLTPDYVKEDLINFKLSEDQAKIVSLKYKQHFIDLSRSLVGNSLSIQQVLDMQWRFGVTTSSSEFTKSNTTGSTFLQLKLVLDKGNNIKEDVHMELTLPQFYEFLKQMQSAKQSLEYLN
The following text describes a protein:
Function:
Functions as an E3 ubiquitin ligase.
Sequence:
MPGNLEPLDLGIQIPYHFRCPISLDLMSDPVTISTGQTYDRTSIDSWIAMGNTTCPVTRVALSDFTLIPNHTLRRLIQEWCVANRSNGVERIPTPKQPADPISVRSLLSQASAITGTHVSVRSRAAAIRRLRGLARDSEKNRVLIAGHNAREILVRILFADIETTSLSSELVSESLALLVLLHMTETECEAVASDPSRVGFMTRLLFDSSIEIRVNAAALIEMVLTGAKSMDLKLIISGSDSIFEGVLDLLKNPISSRRALKIGIKAIFALCLVKQTRHLAISAGAPGILIDRLAADFDRCDTERGLATVELLCRLPEGCAAFGEHALTVPLMVKTILRVSDRATEYAAGALLALCTAEERCRDEAAAAGLVTQLLLLVQSDCTERAKRKAQMLLKLLRDSWPDDSTVHSDDFNRSEVAPF
The following text describes a protein:
Function:
Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MAGLMLLSLMALLGLGAGAPLCLSRQLRMQGDYVLGGLFPLGTAEDTGLSDRTQPNATVCTRFSSLGLLWALAMKMAVEEVNNRSTLLPGLRLGYDLFDTCSEPVVAMKPSLMFMAKAGSCDIAAYCNYTQYQPRVLAVIGPHSSELALITGKFFSFFLMPQVSYGASTDRLSNRETFPSFFRTVSSDRVQAVAMVELLQELGWNWVAAVGSDDEYGRQGLSLFSSLANARGICIAHEGLVPLPHTSSLRLGTVQGLLHQVNQSSVQVVVLFSSTRAARTLFSYSIHCRLSPKVWVASEAWLTSDLVMTLPGMAEVGTVLGFLQQGAPIPEFPSYVQTCLALAADPAFCASLDAEQPGLEEHVVGPRCPQCDHVTLEAMSAGLLHHQTFAAYAAVYGVAQALHNTLLCNASGCPPREPVRPWQLLENMYNLTFRVRGLALQFDARGNVNMDYDLKLWVWRDLKPELRTVGAFNGRLKVWHSQMSWHTPGNQRPVSQCSRQCGEGQVRRVKGFHSCCYDCVDCKAGTYQRSPDDLLCTQCDQNQWSPDRSTRCFPRRLTFLAWGQPAVLVLLILLALALGLVLVALGLFIRHRDSPLVQASGGPRACFGLACLGLVCLSVLLFPGQPGPASCLAQQPLLHLPLTGCLSTLFLQAAQIFVGSELPSSWADQLRRCLQGPWAWLLVLLALLAEAALCAWYLVAFPPEVVTDWWVLPTQVLVHCRMRSWISFGLLHAINAMLAFLCFLGTFLVQSRPGRYNGARGLTFAMLAYFITWISFVPLFANVHVAYQPTVQMAAILLCALGILATFHLPKCYLLLQQLELNNPEFFLGDDARGQGSSGSGGKET
The following text describes a protein:
Function:
May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MNNVIENALRETPITLVLCGLMGMLGVMSSLEVIHPLYLLLSPSLVFKEHQYWRLVTNFLYFGPISAHCIMEIQWIYLVSSYLEAQYYHRRPLDYIFLLLIIGCSLLGLRFSSIVNVPYLSYMLGTCLTYIMSRIFNDMEVAIFFVVPVPMRLLPFVLLIMNTMVSGMTNEVLGNVLGHILWYFLEVFPRITGQSPLRIQRVFERAFAVPVRQAT
The following text describes a protein:
Function:
Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
VGSMALSEKQYLERTGALQRNLHEGEKKRLELERELFTYCRSDRISQIKNTKLRCYLKEICERENQAKIRNLQFLKDFQHIELHLKTLVPDYSTLYQKKVMHLMHVDWVECGNQIAKLLALWKMLQHHIHNLPMESLSQEPATIFMGRQTSRVFNGEMSPMKPSLQPADCISNQYPLSLQELDCKLSCKANVTAKGAECFTGLSDEVRSSRNFNTNRSVPIKNENSVPSASGSILGPVSSPNLEHMASHVIVNAPDKRVPSQTSVGQRESNSPFSRNSDLSTDIMKKSHHESGRCVPHHYCHFSDLENGPQNPVPNAAINMERLENETADTDSDLTVSLSEDGDPSGLLESGGDKDLDSRVYELFCSEKNKTAKYHCRAWCYLSNNKFTLLPEGLVHLMKSIEERLHQREKYLELYKTMSISKEKLNALISLCNHKACLNEEDLEACGAVVLHQLQRLSWSTSKGCLLPEEIVSGNWNTVEERKIRSCLPPDSALLWECWYKHALILEDCHILTTDEIIDLFTPLLVSENSSNISKAKALLKTLLPQMSEGSLSIQSNESSRSLPSILNDSCEIKQAKPAQWLYSTVIGKQVLTELQSGEEDSKEESLVESIPIRETKEYQLLKQSAVQHGRQTSIEEDGLSDTEMSEHLFRTRMSSNAFLTHVKDEGKKKTISAVKSKAFWGESDDSNTDIEAALRPQIHSTNSDDFDDFYD
The following text describes a protein:
Function:
Component of the srb8-11 complex. The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MTSRPPLGVQQRQPQQRKLSGPVLSQQRSLSQSQAQAQAQAQQQQQQQQQQQQQQQQQQQQQQQQQYDASSYLPPPPPVPTRNNNHNNFSNPNNTLNNAFPPELAQQDPTSIVSPADPSGSSPALSVGVGRYGTQRRGGSRLRLELSHNDPFDAFSSPTVIESPGLVEPHTQNGSLTHPMMPLADGPDLGDMSPHHRVSIPPQHLDADVPIPFPQRRPKAVPDHSRREQPPPPPNPARKDTRPKPYTIELPAAAPRYRIRGRSDGQGGQGRSSALATASSSSTTGSSATANYGCADFFPWSGTAGNHPEDQFNDTAIRVGYSEKQFVTPETQSAKTVLFHGLKQRSGLNALSIFFAGVLWHRRNAGQVTAPSTFKPPPRVTLTDTKKEVWLKDLANSAIPLRKLSRSIPHGVRNKVLLDQCLNKNVPIDRAVWLAKCVGTNELRTFRRLGKGNNASVLEGERKWLKDWTLVIENFIERVFFSFGEQNWKAKVNYAIQLAAHLYAEGLMDREHYLDWTVSSLESSHHSQLPMWIIIAQIYWKDLLRLRKYGRRLATALISHYHVIHAHEDRDIYVPLLSKLSHLLGTLMVATPENFVSPSVWVKYRDALKTCLPQGDEARHRSFAGINYRNEQLVASANRSQPAARIILVRNLDQVILEKPMPDEFPAQCWTVSKDKAALVRALLEWCTTPYRPGLAKVYVAHRILMHWSTLRLDVTSAVLGFMEGEALEEMECKDALYHLVSELVRSGIFLVSQYIQWLITRGGLTDPQLVMPDGPPFSRLLAELPSHILGSSQKRSRDALLRRAGFRIADDAQDADMAIRHLRHALGLPAGVTDAVSMGRPFPIKKIARRIEDASRARKAEIASWLRNTVFGGELEHSSLNAFGQHDLSTRLFNSIRTVFEAAQEFSVFADVLRMLTKCSNPEVLASIADTITRYTFVFAALSCLKNLFSILHSRLREVQEQGIGARPLLASLAYLASRVPGMDEVAMQLKSDLAVSDRHNPVDACSPVSDNMVSRLSDHDGDLHEEVEKLLANGTSLDRNTMDRLFSAVIQRLQAYWSKGDEQQRVYGILLKRLRMFNPQHFDELMTRWLLYVRGLDTRATILHLYPLLVSIGCLEMPAILATASESPNALGAGNSRHPQSAVATSQIVQTTFRTRYMQEVLQLFMAPVSSESLLTPEERYRFGILQEQAKKESPRELLCLIQLALAEYTCARAQNDLEELPLDKEANQDRLLRLLKLLVLKDPVGVAKALQIRGPDAQIDGWIDRMTTKLLVTAAGEGTRVTFEQVLNLTNEFTLPFCHVKLLLSLSSNDQQQNAADSGERVPSNVELFMNAMEKSMDAQRVSWIGMLPSLSPDLTHHLKNQAQARFLNLLPSARNPPSMTLDRSMLQMRLQKAENFLAIMDTIIRGSGPMGFRQHQLVPVMVERFTDILELLQTLTPFPSQAGGLGGWGGQGASAAAAGGDSHIDLKSDILNHWLPLFLNFLTLHAQTFDTSKPGNEVRGRALMVCAGLIRELDLIHGPDFDTRQLGGRIFDLACVLVDNLAEDARLQCIQALKSPSDVKLRYIFSYQDNPHANLMLCHKERPTAMAIGTATGTGSPAPGTTPTHTPGVTPGPQNAVGAGSAVSGAGGSGNGGSYFSLPGHTQQAQAQGWHAAQQQQQQQQQQQSQQQQQQQQQQQYQLQQQQQQGGTGPIPSPAISINTNLTHLNLGNNSNPPTPSPMNPTRPAMMMVANPWGGYSWVPTMGGPQERLTPFNFRQWEMLSEPTSQVGENDTAVNLMLFESRKVQ
The following text describes a protein:
Function:
Porin specific for oligogalacturonides. Also required for full virulence.
Subcellular Localization:
Cell outer membrane.
Sequence:
MKIKLLTLAVASLVSVNALAVSIDYRHEMQDTAQAGHKDRLLISHRFANGFGLSSEVKWAQSSADKTPNKPFNEQVSNGTEVVASYVYKFNSVFSIEPGFSLESGSSNNNYRPYLRGRANVTDDLSVALRYRPYFKRNSGNIGKDNTMDKGYTLTGNIDYTFLKDYTIGYELEYKKGTSGKTILSDNDDYDITHNVKLSYKWDKNWKPYVEVGNVSGSETTDERQTRYRVGVQYSF
The following text describes a protein:
Function:
Lectin that functions as a pattern recognizing receptor (PRR) specific for beta-1,3-linked and beta-1,6-linked glucans, which constitute cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and activation of NF-kappa-B: upon beta-glucan binding, recruits SYK via its ITAM motif and promotes a signaling cascade that activates some CARD domain-BCL10-MALT1 (CBM) signalosomes, leading to the activation of NF-kappa-B and MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) pathways which stimulate expression of genes encoding pro-inflammatory cytokines and chemokines. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation. Induces phosphorylation of SCIMP after binding beta-glucans.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein.
Sequence:
MEYHPDLENLDEDGYTQLHFDSRSNTRIAVVSEKGSCAASPPWRLIAVILGILCLVILVIAVVLGTMAIWRSNSGSNTLENGYFPSRNKENHSQPTQSSLEDSVTPTKAVKTTGVLSSPCPPNWIIYEKSCYLFSMSLNSWDGSKRQCSQLGSNLLKIDSSNELGFIVKQVSSQPDNSFWIGLSRPQTEVPWLWEDGSTFSSNLFQIRTTATQENPSPDCVWIHVSVIYDQLCSVPSYSICEKKFSM
The following text describes a protein:
Function:
Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin.
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MKRGKCKEKDNGLKRISSESEVWNFLDVTVSELNKQKRSPGQTVSKRLHKKQRVVSNPDLSLPSSPVKQILRNGLQNSKYGSHKTGLERSASCSSIDASANHSSTTYREQRSYLMEEGLDTQPIVPREVSSGRELDSTNHTIGTERAFLIEEDVSEDDEIQMKSIHELRFAGEQQRIVDEIEYLVDGVTFSGNSSASRYLSLIGIAEKMFDNSFRLCLKSIRDVFLRIFEEIDPKDTLHTFLQIYIFATMANEMDCMSSLLDAYSNNVKLLLQTAITLEPQVPVSILAKSLPKSVKGAVQEFVIKAELTFSFSNESLASSDSISLAAIALMKTSSGVFAESELFTELINLLIEKSYPILKENDGSNNFLLHALCSSLEKFTDFQGSEKIQKVSQILSSKLQILIDEHNETNSPKIDDTVVHACSEKLLRTLIQTVNSNSDHALAVSKSEVPLFAYKILQKFSNFSSDDETTRELIILILGLLLGLVEESHEFIQTITHVEVSFGASALDVLISFYQKNESIVEISGYVVMILSHCFLNDPKAFAQLKPLISQFYESLHKFKNFHLKLKEELMMMGSNGLAIVSIIDELHKSLQDYLRSDLVK
The following text describes a protein:
Function:
Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
Subcellular Localization:
Nucleus. Mitochondrion.
Sequence:
MTTFEGFGLSKVVSSEETQSGQKSLVYIKNKNILNWSLEDVCIWLKSKDLGVLVDSFSKLKVDGNFLLGINEGDLKKLGITCIPRGKILKFEDALSELKMGYYSLVTSETPSLFVNDEQTSPLLGIVDFKEYNRTLIGQGGFGEVYKMVHKTNGSTMAMKQIPILKNSKIFEEVKILSKLKHDNIIKILSYQNDENHLSIFFEYFPDSISSVYKTNGAFNESRCRAIITGVLNALVHIHSEKIVHRDLKGDNILLKGNHPYIIDFGLSHNFDRESHSTFYSKAGTHFWQSPEVRLNTIGECGRSSDIWSLGCTIVEMLVGGNPWQNIKVEDGYHPPIPPNLSVNLRDFLNACFLISPEFRPSAKKLLNHPWIQGKPDLLKEITKQEIITSSTLLIEYISKGACFFINQAKKDILPFEPIVYSQSIEYKKNLEEHQQYVSQLGQAKSDEILKTFYIKVEQKKYIKTRFYKKIAKLRWEEVWNKIEVMRKENIAPVDTLGAESFNIEEIEPKERRFHILVGCLLSSQTKDQVTHAAMVRLKEYGLNVETVLKTPNEKLETLIHPVGFYRRKAVYLKSIAEILKEKYNGDIPPTFKEIEALPGIGPKMTNLIVQIAWGRVEGIAVDVHMHRICNRLGWVKTNTPEETMRQLESWLPREKWGQVNHLLVGFGQTICDPVRPKCSSCTVNNLCPVGIKEMKSLNKQEEKKKKKLK
The following text describes a protein:
Function:
Plays a role in the inhibition of apoptosis by interacting with the pro-domain of pro-caspase-8/CASP8 and thus preventing its activation.
Sequence:
MDDLRDTLMAYGCIAIRAGDFNGLNDFLEQECGTRLHVAWPERCFIQLRSRSALGPFVGKMGTVCSQGAYVCCQEYLHPFGFVEGPGFMRYQLIVLIGQRGGIYCYDDLRDCIYELAPTMKDFLRHGFRHCDHFHTMRDYQRPMVQYDDYWNAVMLYRGDVESLSAEVTKRGYASYSIDDPFDECPDTHFAFWTHNTEVMKFKETSFSVVRAGGSIQTMELMIRTVPRITCYHQLLGALGHEVPERKEFLVRQYVLVDTFGVVYGYDPAMDAVYRLAEDVVMFTCVMGKKGHRNHRFSGRREAIVRLEKTPTCQHPKKTPDPMIMFDEDDDDELSLPRNVMTHEEAESRLYDAITENLMHCVKLVTTDSPLATHLWPQELQALCDSPALSLCTDDVEGVRQKLRARTGSLHHFELSYRFHDEDPETYMGFLWDIPSCDRCVRRRRFKVCDVGRRHIIPGAANGMPPLTPPHAYMNN
The following text describes a protein:
Function:
Transcription factor required for sporulation and for early sporulation-specific genes expression. Positive regulator of SME1/IME2 expression. Directly activates expression of SLZ1 during meiosis.
Subcellular Localization:
Nucleus.
Sequence:
MQADMHGKLHAALEDGFFLFPFEQQQQPNIYYDTTTDQEDRPCFSFGSTISPRSWHFEKSDKIASSQLQNLVHTQPIHLINPQILFNEEFLNLENIDSQPISKETKTTKDCTMATGPERGKKSSESTRSSSLSSLFSNDESASTFHSSFNNHDNFQKSNRNGDDIDISDTIKYETNTNAQKDIKIFQENFEFNEFPYTQDFYPYTTNYTYSKPTNIHESINSKNTDSYSQYQDQFPPHTDNIHSFNNRHYSNHKSTNCNYYNNTSNNNNASDNVYEADPFIDEPQVPSYYYPLEIAFDVEKSPPPSLQKLNSKELEFLKKLNSKLSRYAAAYSFSSSNDQDYYDKVRFQEISYKFSKTYS
The following text describes a protein:
Function:
Probable regulatory subunit of serine/threonine-protein phosphatase 4 (PP4).
Sequence:
MTLVEYSETLKKSLEEFCKQDKKVVTPELNSIIENISKTGITCYPWNILKELFYFKLNEILDIFEKEYIATSSTTTTSTTTTTTNTSSSSTNSPQSPQSPQSPQLNVNIKDEEMQKIKNQVNLSGLIKMKKEFLDSFKESKLSPFTVQRLCELIINYKMYTSFSKYLCAVEKMLNVSTLPHLTPEEVIEFNKNQNSGSRLNSSTNTTTTTTTTTTTTTPTEKGNNDQPNLDSFAFSSSFTTSFPSDTTSSTSTSLSTDQEMKDLDVEQQKDDTDNTANENESK
The following text describes a protein:
Function:
Involved in the glycerol metabolism. Repressor of the gol operon for glycerol metabolism.
Sequence:
MFPFERQNKIIHLLDQNNKITVPELSRILDVSISTIRNDLSALEESGMIKKVHGGAVLLKSEEKFTNFNDRIIRNIEEKEAIAKEAATLVKNNQTIILDASSTALALAKELHGFSRLTVITSGLYTAIELKDNPNISVILTGGIVTTNSFTLEGILGANLIENIHADLCFMSAKGFTMEEGLTDFNIYETELKRLLAKRTNKLVALLDHTKMGVISTASITTAENIDLLITDNKINKALYKKFQDAGLPVKIAE
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Chromosome, centromere, kinetochore. Nucleus.
Sequence:
MSSRGSNSRMSSIPAKLPRSSGVYMKRPSLGGPPMPPGGHHRPSLSRQSMAFSSSKGASAQDPRNINDKSFQKEATAELIEYLTTHGFNSPISSKLPSGKEIKDIIEFLFRQVDPHIVFGKLEDDVPGFFRSLNYPFQISKSALYAAGSPHSWPGLLAALAWLVNLLTYEEKAREIKEGNGGGFGYEGSGDLIFFEYLSQAYNEFLCGNDEACAKLDADFRVQFEEEKAQLVQQAEELEKTVNDLQAKLHTFTSEPSPLAVLESKKADFLNDVAKFTTIISNFQSHKEASLKKMEEKREDLLALKTEASNIAEENEALRQRIGAQQLSVAGVEKMDKESQILETRLHAVSKAAQELQKEAWDKEVQSANMLREVEDVVITYNTGSARLKNMYPELEARQVQLEMKVNSREEKPEDILGFNVKGVFKPLVASLMESIEKATRDAREEVLVMQKKLYADEVSFQEKSDEVSTLVTQNKKLEAQYKGRKERLDNYIASKAAQRAQFEKSLAEKQTTLRQKLNADYEIKLKAYKEEMEQEQAEALEALQMYAEHNEYIQQALSRLEDRAGQVLKMARRD
The following text describes a protein:
Function:
Zinc metalloprotease. Able to degrade azocasein in vitro.
Domain:
The HEAIGH motif probably functions as the active center of the metalloprotease.
Sequence:
MFKYIKKAEELGASFADIRYERVIANEVTITEDRKYVSHGVDEGYSIRVIYNRNWGFKATDKITENEIEDTINHIYGDERVNIVYLPSKHDTIKIGKDINKNEEEKINDLHKVASQVNTLHPSIKSYSIKYYDEIFHKEYYSSEDREIIADGSSSSLSILVVAREGDVTVEVSEILSTQMGYIFDVFDINQVLANLQKRIINQLKGSTPKAGEYPVILAPEVVGIFTHEAIGHLSEADVTLNGSLYKLRNKRIGDEFLNISDLPAMDHPQSSLVYYDDEGVEGREVKIIENGILKEFMTDRYYSAYLGQPPTGNARAQSYRNFSLIRMRNTYMKPGDASLNELFEGIKEGYYLVSPIGGETSSNGTFQFAIQEGYRVENSEIKEPLRNIGISGNTISTLNAIEMISKDFGMSSGFCEKNGQTVQVSNGGPHIKVKKLKVGGYV
The following text describes a protein:
Function:
[Major capsid protein]: Major capsid protein that self-associates to form 120 hexamers and 11 pentamers, building the T=13 icosahedral capsid which about 860 Angstroms in diameter. Responsible for its self-assembly into a procapsid. The phage does not need to encode a separate scaffolfing protein because its capsid protein contains the delta domain that carries that function. The capsid gains its final stability through the reorganization of the subunits that takes place upon expansion. DNA encapsidation through the portal triggers capsid expansion and the binding of the decoration protein to the capsid exterior. Might play a role in counteracting the host Pycsar defense system that is mediated by pyrimidine cyclases and leads to abortive infection.
Subcellular Localization:
[Major capsid protein]: Virion. Note=Forms the icosahedral capsid shell which contains 775 major capsid proteins.
Domain:
[Scaffolding domain delta]: The scaffolding domain delta has a role of scaffold allowing the self-assembly of the capsid protein.
Sequence:
MTIDINKLKEELGLGDLAKSLEGLTAAQKAQEAERMRKEQEEKELARMNDLVSKAVGEDRKRLEEALELVKSLDEKSKKSNELFAQTVEKQQETIVGLQDEIKSLLTAREGRSFVGDSVAKALYGTQENFEDEVEKLVLLSYVMEKGVFETEHGQRHLKAVNQSSSVEVSSESYETIFSQRIIRDLQKELVVGALFEELPMSSKILTMLVEPDAGKATWVAASTYGTDTTTGEEVKGALKEIHFSTYKLAAKSFITDETEEDAIFSLLPLLRKRLIEAHAVSIEEAFMTGDGSGKPKGLLTLASEDSAKVVTEAKADGSVLVTAKTISKLRRKLGRHGLKLSKLVLIVSMDAYYDLLEDEEWQDVAQVGNDSVKLQGQVGRIYGLPVVVSEYFPAKANSAEFAVIVYKDNFVMPRQRAVTVERERQAGKQRDAYYVTQRVNLQRYFANGVVSGTYAAS
The following text describes a protein:
Function:
Required for the activation of chitin synthase III (CHS3) activity during the sporulation process.
Subcellular Localization:
Cytoplasm. Cytoplasmic granule membrane; Peripheral membrane protein.
Sequence:
MSMTICSNTPGAYPEIGAYNEVDKQLESSGFSSDSSLILNKPEVRQYWSSVSSHISRSGDVFTNDKEKISSSIGEDAMDIDASPSLIEKYNSFPTRKILPEQDEFENDVEDDASSSLKEKSQGSCEIEIASEISSEILNGTSADGNSEFHDFAEPPPSQNESVALSFSQSNDLDFLNNPSGSGSSNDINRSTSSISLPRHVSLDFNVYNSLCLTNEVTASESHNVAKFHLGKKNKKSLLPRWKTIEMYGEVVKKTQDIYSNFQYAQYILRVGLDTEKLHELVKELEDESNSFSVDSLKEYLVNDAKVILKKLSAVGYPDAQYLLGDAYSSGVFGKIKNRRAFLLFSAAAKRMHIESVYRTAICYECGLGVTRNAPKAVNFLTFAATKNHPAAMYKLGVYSYHGLMGLPDDILTKMDGYRWLRRATSMASSFVCGAPFELANIYMTGYKDLIISDPDYAMALYEKAAALGHTESARILEDARRSGGFVSRGHPPSAQKYHKTSHEAVAAKKLI
The following text describes a protein:
Function:
May be involved in cell wall biosynthesis.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Sequence:
MDMHDSGRASGMKCYELIINRAVLSLLLLYFGFMFSRTGDLDEMIQHFRKYLSPASAEADAHRVKDDYPLKNLDLALDPEVHQLLDMLKNASREAPPSKGYTRLDRALWDSENSCKSRVELPERYERRKHVENIEAPMGFKILMEQYEKLHRNCIRGSGNLTSLFFRHQSGDDDDGNGCKFLVAEAGNGLGNRVLWMVSTLLYAVLAGRVILIDPRSLIPSLMCEPFSGSSWVAPSEFPFADLRPDLWVSPDEFVAGIDAAAAKNGSNITLPSFKAVRGDDSWGPTSRFYCPMEQHLYSRVKWVTLGGCLYFLPELFAIPTFKLALEATFKNRVPLTHLLRSAMLPRDSVWNKVKDVLDGPFTQADELIGVHVRYRGGYVQYQNLNAHVNHKVHQCLLAGGLLRPGHHPLTFTNSSTLIFISSLYPGLHDELVKLYPRGNEDRVNILQLSSEGEQYSGLQIDEGALVEILSLSLCDAVLISPMSTYSTLAHAYGGMTPWIINFQDDQGPCTRAQALDGCYQGAGVFYVCPLDPAVDKQPIMKLVPSLKPCQDSSGVQLVH
The following text describes a protein:
Function:
Cleaves internal linkages in 1,3-beta-glucan. May contribute to plant biomass degradation (By similarity).
Subcellular Localization:
Secreted.
Domain:
The CBM6 domain binds the non-reducing ends of beta-glucan; this domain may therefore target the enzyme to polysaccharide termini in damaged regions of the plant cell wall susceptible to catalytic attack; The CBM56 domain modulates binding affinity for beta-glucan and aids binding to insoluble beta-glucan.
Sequence:
MKGKNVQLLFALVVIILLFPTGASASPHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQESSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNGDGPTNPDPSEPDLKNPYERIQAEAYDAMSGIQTEGTDDDGGGDNIGWINDGDWVKYERVHFERDASSIEVRVASDTPGGRIEIRTGSPTGTLLGDVQVPNTGGWQQWQTVTGNVQIQPGTYDVYLVFKGSPEYDLMNVNWFVFRANGQGNGDSHTHPDYTAGIRGITGNEVTIFFAPTTEARYVDVHLKVNNGQQLNYRMTERNGEWERVVENLSSGDVLEYSFTYEKLGPQYTTEWFTYSR
The following text describes a protein:
Function:
Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
Subcellular Localization:
Cytoplasm.
Sequence:
MFQVQKELAGHEAVIVALFEEEKMSSFVQELDKAFEGQLQVLLEEKELSTKKKAISKVHSLGKTNVKRYYFVGLGKKESYTTETLRAALGKAFKTLQAAKVQDAAILLDSFVTEKLDAIDVAHIAAEVQGLGTYELQTYKSDKKDRVELEKFMAITSEDAQEIEAALTVGYVHGRATNSARTLVNMPPNVLTATKLAEYAVELAEKYDMDYKVLEKEEMEDLGMGALLAVNQGSVEPPKMIALIYKGKEEWKDVIGFVGKGITYDTGGYSLKPREGMVGMKGDMGGAAAVLGAMEIIGELRPEQNVIAVIPSTDNVVSGTAFKPDDVITSMSGKTIEVLNTDAEGRLALADGITYAKKLGANYLVDVATLTGGVIVALGNYTTGAMTNNEELFEQVLEASMETDEPIWQLPIFDRDKERVRNSKFADLNNSPGREGHAVMAGTFLGEFAEDTPWVHLDIAGTSETKGAHDLGPAGATGAMVRTLATLVERFGEE
The following text describes a protein:
Function:
Inositol phosphate kinase with a broad substrate specificity. Phosphorylates inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) first to inositol 1,3,4,5-tetrakisphosphate and then to inositol 1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5). Phosphorylates inositol 1,3,4,6-tetrakisphosphate (Ins(1,3,4,6)P4). Phosphorylates inositol 1,4,5,6-tetrakisphosphate (Ins(1,4,5,6)P4). Phosphorylates glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate to glycero-3-phospho-1D-myo-inositol 3,4,5-trisphosphate. Plays an important role in MLKL-mediated necroptosis via its role in the biosynthesis of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Binding of these highly phosphorylated inositol phosphates to MLKL mediates the release of an N-terminal auto-inhibitory region, leading to activation of the kinase. Essential for activated phospho-MLKL to oligomerize and localize to the cell membrane during necroptosis (By similarity). Required for normal embryonic development, probably via its role in the biosynthesis of inositol 1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5) and inositol hexakisphosphate (InsP6) (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MAAEPPALRLRPPGSTGDSPPVPRLLGGCVPLSHQVAGHMYGKDKVGILQHPDGTVLKQLQPPPRGPRELEFYTMVYAADCADAVLLELRKHLPKYYGVWSPPSAPNDVYLKLEDVTHKFNKPCIMDVKIGRKSYDPFASAEKIQQQVSKYPLMEEIGFLVLGMRVYHLHSDSYETQNQHYGRGLTKETLKEGVSKFFHNGFCLRKDAVAASIQKVEKILQWFENQKQLNFYASSLLFVYEGSSQPATTKSNDRTLAGRFLSKGALSDADVLECNNNFHLFSSPANGTSVGKSLSKAYSRHRKLYAKKHQSQTSLKVETLEQDNGWKSMSQEHLNGNVLSQLEKVFYHLPAGRQEIAEAEVRMIDFAHVFPSNTVDEGYVYGLKHLIAVLRSILDS