lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Carbamate kinase involved in the arginine deiminase pathway of fermentative arginine utilization.
Subcellular Localization:
Cytoplasm.
Sequence:
MSYTVVALGGNALLRGGEGSIQDQRDTIEQTVPHFVDLYERGHELVFTHGNGPQVGQLLLQNEEAESAAEKPLDVLGAESQAQIGYLLQQQLREELGETPATVITQTIVDEDDPAFDDPTKRIGPFYDEDEASEKDFPVKEGTDGDGNVGYRRVVPSPKPVDIVEAEHIKTLVETGKPVISSGGGGVPVVEDGDSLTGVAAVIDKDRAAQSLATDIGADEFLVLTDVDAVYRNFGTEDEEELSELTTEEAADMLAAGEFGEGSMAPKVEACIEFVESGGDRAIITKPETATEALDGAAGTTVVPADE
The following text describes a protein:
Function:
Plays a role in rod outer segment (ROS) morphogenesis. May play a role with PRPH2 in the maintenance of the structure of ROS curved disks (By similarity). Plays a role in the organization of the ROS and maintenance of ROS disk diameter. Involved in the maintenance of the retina outer nuclear layer.
Subcellular Localization:
Photoreceptor inner segment membrane; Multi-pass membrane protein. Photoreceptor outer segment membrane; Multi-pass membrane protein.
Sequence:
MAPVLPVVLPLQPRIRLAQGIWLLSWLLALVGGLTLLCSGHLLVQLGHLGTFLAPSCSFPALPQTALAAGTVALGTGLGGAGASRASLDAAQYPPWRGVLTPLLAVGTAAGGGLLTLALGLALALPVSLNQGLEEGLEAALAHYKDTEVPGRCQAKRLMDELQLRYHCCGRHGYKDWFGVQWVSNRYLDPSDQDVVDRIQSNVEGLYLIDGVPFSCCNPHSPRPCLQSQLSDPYAHPLFDPRQPNLNLWAQGCHEVLLEHLQGLSGTLGSILAVTLLLQILVLLGLRYLQTALEGLGGVIDGEGEAQGYLFPGGLKDILKTAWLQGGLAHKPAPEEAPPDEEPPKEVLAEA
The following text describes a protein:
Function:
Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
Sequence:
MGSGMTMIPQSQDRSALEQEQFLKILSREEAMARFEAALFPRAIPSETRKLADTLGTALAEDVTAPIDVPPFDRSNVDGFAVRSADLAAAGEGAPVRLALNGETIHCGTAPRMQVATGTATPIATGGPLPRGADAVVMVEHTQPAGPDAVDVRRAASPGQFVSYAGSDIARGEALLRAGTLVGSREIGMLAACGIAEVAVARKPRVAVISTGDELVQPGEVLAPAEIHDTNGAIVAAAIDENGGEAIFLGAIPDDEAKLESAMRRALADADMLVLSGGTSKGAGDLSHRIISRLGQPGVVAHGVALKPGKPLCLAVCDGKPVVILPGFPTSAMFTFHDMIVPVLRRMAGLPPRSDAKVSATVPVRIASELGRTEFVMVSLVEGRGGLIAYPSGKGSGAITSFAQADGFLRIDALADQMPAGTEAEVTLFTPHVRVPDLVIVGSHCTGLDLVTAQLAHAGLTVRSIAVGSLGGLAAAKRGECDLAPIHLFDDRSETYNTPYLVEGLELVPGWRRMQGIVFRKGDKRFEGLSAKDAVAAALTDPACIMVNRNQGAGTRILIDRLLGGARPEGYWNQPRSHNAVAAAVAQQRADWGMTIAPVAHAVGLGFIPLAEEHYDFALVTARKQRPAVQAFLDALGSGEARTALERAGFRPA
The following text describes a protein:
Function:
Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MATYFLVMMFGIGAWIAVNGLWVELPIIVQEIPESWSLPSYLTVIIQLANIGPLAFTLGNKFLPRFVKEIPVTYALVVIGVLASALLAHFWKETIYIAGADRSAALLILAFFLSMVDCTSSVAFIPYMSRFPMVYLSPYFLGEGLSGLLPSLVALAQGVGEGASNERCVAQPVYNSSSNSTSGSWGPGPRFTPKVFFWFLSVMMACCGLAFLALNTLQVTKKQQVKEREYDVTTSDMHELQEISKTEAQSTSDIQVTDNILTTRQNVFLLVILAIVNGLSNGIIPAIQSYACIPYSYYIYHLTLTLSNIANPITCLMFPLLRVKSIPVITFLCGVYCVMCTYIIIIASQSPDVLLRCGDTGAALIVVISVSSVAMVTYCKVAISSLMRNQGRKKLLWFGISTQLGSCIGALSIFVPVNVYYMFKQY
The following text describes a protein:
Function:
Component of a cytoskeletal structure that is required for membrane curvature.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MSWIGIKKAINRAGTQVMLKTGHIEQTIDKEYEFQEKRYRTMEENSIKLQKNLRLYLDSLRLLTNSQINIAESLNSFYGTNNDKRSSNISRTGSVNTGDKIQTIHEEEGEEKEEEENDNTTTTTTTTTTTITTTNTTYNYNNLIQEYYATIKQLNDSCIANLENPYNQTVLNPIARFNSYYIEINEIIKKRHNKLLDYDAMKNKLRKLIENPTTNISPSMKTNIIELNHNQYEEKLKIYNQELTEVESKYVEINNQLLIELPKLINHRISYFDPSFESFVKIQLRFFNENYHVLNQLQLKLDAQTRQDYIEGKLEDRIDDVLRKMKKLDITSGLD
The following text describes a protein:
Function:
ATP-dependent RNA helicase required for ribosome biogenesis. Involved in the release of U14 snoRNA in pre-ribosomal complexes. Required for pre-rRNA cleavage at site A2 (By similarity).
Subcellular Localization:
Nucleus, nucleolus.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MPPSSAAEGSTKRKKGGAAPHLKSRSKNARKLKRSAEDAEIAQLEQGIQAFVSPIDLKQFTQLPLSDRTCRGLKRAGYTDMTDIQAKSLSLSLKGKDVLGAARTGSGKTLAFLIPVLEILYRRKWGPSDGLGALVISPTRELAIQIFEVLRKIGSYHTFSAGLVIGGKDVKQEKDRLSRINILIATPGRLLQHMDQTLGFDTSNVQVLVLDEADRILDMGFSRTLNAIVENLPRNRQTMLFSATQTKRVKDLARLSLQDPEYVAVREPENEGCTPRGLEQHYMLVELEKKLDLLFSFIRTHTKCKALVFMSSCRQVQFVHETFCKLRPGVSLMALHGKQKQAKRLQIFTQFTKTQHALLFATDIAARGLDFPAVDWVIQLDVPEDVDTYIHRVGRTARYTAKGNSLLFVLPSEEKGILEALATKNIAIGRIKPKESKTQSIQNQLQAFAFQEPQIKHLAQKAFVSYVRSIHLQKNKEIFDVTALALEPFAAALGLPGAPKVKFVKEAAKAKKAAAYKAAQQQADDNSGQVKGDSDDEQAERADKNGKVRTKYDRMFERKNQDILSKHYANLIADDASSEQDSSNDSDTSDDDSVSVATTDNDDAEDREETRYGRSAGRRKENRLVGSDTSDSEEDESDDEQNDSGLHKIKSETKRSVMAARGDGDDGFLTLKRADHALEDDGDAYGIGGDDTRITMEQAKADATENLSKRKLAMGQSKKALALAGKRGIGEKLIFDEHGEAHALYELQDEEAFNKQGDAKTQAQRWAEEERERMQQADAKDKELAKEKRREKRRRQKEREKALERGDAPDNGDEGGSGDDDEEEEETGGRAVLAPIDNRSDGYETPDFDLTTEEDEDDDDDADDDDDDDDEAYRAPAPKRRKMAPSAGVTSQPSHSKKSKLEQEEELALRLLAGDA
The following text describes a protein:
Function:
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Catalyzes cleavage of bradykinin, substance P and neurotensin peptides. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of the atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein.
Sequence:
MGRSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATIEPCADFFKYACGGWLKRNVIPETSSRYSNFDILRDELEVILKDVLEEPKTEDIVAVQKAKTLYRSCINESVIDSRRGQPLLKLLPDIYGWPVATENWEQIYGTSWTAEKSMAQLSSKYGKKVLINFFVGTDDKNSTYHIIHFDQPRLGLPSRDYYECTGIYAEACNAYVDFMISVAKLIRQEEGLPIDENQLSLEMKKVMELEKEIANATTKSEDRNDPMLLYNKMTLAQLQNNFSLEINGKPFSWSNFTNEIMSTVNINIPNEEEVVVYAPEYLIKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDELTWMDAETKKKAEEKALAIKERIGYPDDIVSNDNKLNNEYVELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKNEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSANNFKDQSQCMVYQYGNFTWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFNCRKNSYMNPEKKCRVW
The following text describes a protein:
Function:
[Protein AimP]: Part of the latency-replication switch system which decides at the onset of infection whether to replicate and lyse the host or to lysogenize (latency) and keep the host viable; [Arbitrium peptide]: Peptide which is released by the infected host bacteria and acts as a communication agent that affects the latency versus replication (lysogeny-lysis) decision for any new infecting virus from the same specie. High concentration of arbitrium peptide results in increased lysogeny in the upcoming viruses. The arbitrium peptide is secreted by infected bacteria and, after several cycles of infection, accumulates in the extracellular medium. When a virus from the same specie subsequently infects an uninfected bacterium which has internalized the peptide via its OPP transporter, the peptide will binds to the viral AimR transcriptional regulator and prevents AimR transcriptional activation of the aimX locus. Inhibition of aimX transcription promotes lysogeny.
Subcellular Localization:
[Arbitrium peptide]: Secreted.
Sequence:
MKKVFFGLVILTALAISFVAGQQSVSTASASDEVTVASAIRGA
The following text describes a protein:
Function:
Mediates cell adhesion in a Ca(2+)-independent manner. It plays a role in axon outgrowth, guidance and fasciculation of the developing nervous system. Function in neurons is essential for adult survival, and is important for climbing behavior and activity.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MSRIVFICLAAILTDALTWAQVNVEPNTALLNEGDRTELLCRYGRSINYCRIEIPGEQKVLNLSPEWSKTPGFTYFGAGLTAGQCGVSIERVKASNNGQVKCSLGVEGEELSGTIDLVVALRPQQPIIELLSRPNREGYFNEGTEFRARCSVRDGRPPANISWYIDNMPANKRTTPLEVMSSTNDNVELSTSVQEIQWHLSPEDSNRKLVCRSHHQTDRESVPPQEAAYIINVRYAPVHQPDAAVYGLYLEHTAIVNITIRASPQPKIEWTIDGAIVGQGRTDGRYSAYEPQYLGNDEYNVTLAIAGLTLEDTTKIYNLRASNELGLTDYQVRISSSSKPPSSSLDVAAIVGIVVAVAVLVLVVLLIVFARATGRWCFGGKSIKTPTNETSDTESADIKATSTATATTTMGGVGVSAEEEETVNEQESPQEQQQQQQKKAKRLPAFAAAILRRFNEKDSRKYKDNQESLNIVEGSVQEIPATNNAIDGNDNEPKAIVWQSTSPVWTFK
The following text describes a protein:
Function:
Degrades proteins damaged by L-isoaspartyl residue formation (also known as beta-Asp residues). Degrades L-isoaspartyl-containing di- and maybe also tripeptides. Also has L-asparaginase activity, although this may not be its principal function; May be involved in glutathione, and possibly other peptide, transport, although these results could also be due to polar effects of disruption.
Sequence:
MGKAVIAIHGGAGAISRAQMSLQQELRYIEALSAIVETGQKMLEAGESALDVVTEAVRLLEECPLFNAGIGAVFTRDETHELDACVMDGNTLKAGAVAGVSHLRNPVLAARLVMEQSPHVMMIGEGAENFAFARGMERVSPEIFSTSLRYEQLLAARKEGATVLDHSGAPLDEKQKMGTVGAVALDLDGNLAAATSTGGMTNKLPGRVGDSPLVGAGCYANNASVAVSCTGTGEVFIRALAAYDIAALMDYGGLSLAEACERVVMEKLPALGGSGGLIAIDHEGNVALPFNTEGMYRAWGYAGDTPTTGIYREKGDTVATQ
The following text describes a protein:
Function:
Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MGAINQGISLFDESQTVINPINTNHLGFFFSFPSHSTLSSSSSSSSSSPSSLVSPFLGHNSLNSFLHNNPSSFISHPQDSINLMTNLPETLISSLSSSKQRDDHDGFLNLDHHRLTGSISSQRPLSNPWAWSCQAGYGSSQKNNHGSEIDVDDNDDEVGDGGGINDDDNGRHHHHDTPSRHDKHNTASLGVVSSLKMKKLKTRRKVREPRFCFKTLSEVDVLDDGYRWRKYGQKVVKNTQHPRSYYRCTQDKCRVKKRVERLADDPRMVITTYEGRHLHSPSNHLDDDSLSTSHLHPPLSNFFW
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MVYGLVRSVQAALKYRGGWKGLLEHMYTNGDYPFKFGTYMGTDPSGNRYYENRVDYPFGQHRWVEPGDIHNFDSASIPPEWHGWMVSMNDAPPSAEESYIEGRKGDIIEMCKSDAGIDHNVGHQEKIYNFHHLHNLSTVRSRGYGIGNPIVGLPPDAKDSYYTQPGSPYNEASIRPRVNIGDLGGGRVYKSEKWADRLRTKEEKEAIEKERLASVDRAIAAGKAAGDRRKRALAMRGDGTVAGA
The following text describes a protein:
Function:
Putative transcription factor.
Subcellular Localization:
Nucleus. Note=Interactions with MIF proteins prevent nuclear subcellular location and leads to a scattered repartition throughout the cytoplasm.
Domain:
The homeodomain differs form the typical one by having namely 4 instead of 3 extra amino acids inserted in the loop between helix 1 and helix 2.
Sequence:
MDEIKPKKEENSKRRRNVKPICRETGDHVHYLPTCKTKPKPTRTHHAPPPILDSIFKVTHKPHYYECRKNHAADIGTTAYDGCGEFVSSTGEEDSLNCAACGCHRNFHREELIPENGGVTETVLEVLKISSCQFRRIFCSPYGGGKSEGKKKKKEKESYGGDPIIKDRFGGAEEEEGIVKRLKTKFTAEQTEKMRDYAEKLRWKVRPERQEEVEEFCVEIGVNRKNFRIWMNNHKDKIIIDE
The following text describes a protein:
Function:
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MATLHFVPSAFSLPKQKQPIKLSSVRPTTQISCSRRRLVVRSYKVVIEHEGQTTELEVDPDESILSSALDNGLEIPHDCKLGVCMTCPARLVSGTVDQSEGMLSDDVVAQGYSLLCVAYPRSDCHIKTIPEEELLALQLATAND
The following text describes a protein:
Function:
Mediates cell-substrate adhesion and promotes biofilm formation.
Subcellular Localization:
Secreted, cell wall. Note=May be GPI-anchored.
Sequence:
MRKLPLFMAWKFWLICLYIIKVASTQIVIKSNTIVGGNNPSGFQNGYIVSGDAFLAFQDMNTVPMYQTVRIDKGGALYYINNDKQGFSILSDHNYNHPFVFLNEGTVVVDDRRSISPGSWTIKDGSFTNNGNIMFTSSQGDIFSIGSNYITNTGFIFSKGTSFEKPQRLQIGNGNIWINTGTVCMANTTYILENAIQGGGCISVGENSVFNIYSFDMQQQTVYLSHPSSVLILNGGHEVPVYGLGNGNGILYPDAPIRDIYYDSSTGIMDVTAGTNGIYKFTVYIGAGYNESNFEIVSSIKIHGISYDNYNFVRYRGPPPNLAPSVCQPCVEIPLYSFQVPDPYTTTNELGFSETVSFYSTYNENDIPVIGNTTIYVPPAIYTLTKVNENTTETDIISRVTGMGYNGLPFTYYTTITVGEMETGVVTKTITITENKSRSTKTTLMSRNYTFSFSNYSPISSSGTYSVSTVDNITTLTDTVANVSSSGPNSIVTATMTTYQNNHEFNNASVINVTNSSNIMVPITSTFYSSVDSNLTTPITSLTRTSQSQIVSHITKLASSINETTIANTFPSPAASGTNYTTVVTNAEGSVQTDIVSHITTTDSDGKPTTIVSHITTTDSDGKPTTIVTTFPAPAASGADYTTVVTNADGSVETDIVSHITTKDSIGKPTTVVTTVPYTLCASNADYTTVVTKSNVSVETEVVSHITTTAPCSDLESHVENQTTSPSMHTTSLVGSENGVSAKTVNDKPNPTIFTEVAVSEGTTSNAGYVTDQGSSLEMFAPTGASAVESGNKVSQTQTASIFHGAGSTFKIKFNTILLSTSLTILILLGMA
The following text describes a protein:
Function:
Enzyme with a broad specificity. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172'. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
Subcellular Localization:
Cytoplasm, cytosol. Membrane; Lipid-anchor. Note=Weakly associates at the membrane and N-myristoylation mediates the membrane localization.
Sequence:
MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLDNWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAADKSGSALEPSVESVKTGIRTGFLKIDEYMRNFSDLRNGMDRSGSTAVGVMVSPTHMYFINCGDSRAVLCRNGQVCFSTQDHKPCNPVEKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEIVRAEEDEFVVLACDGIWDVMSNEELCEFVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSVVLVCFSNAPKVSEEAVKRDSELDKHLESRVEEIMQKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKRHVIEAVYSRLNPHKDNDGGAGDLEDSLVAL
The following text describes a protein:
Function:
Probable transporter of a GTP-driven Fe(2+) uptake system.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MRKVTVAVTGNPNSGKSTLINAIAGISLQIGNWPGVTVEKKTATLKIDELMVNLVDLPGTYSLSPYTQEEVIARDFLVQEKPDLIIDVVDSTNLERNLYLTVQLLELGIPIVVTLNIFDEAKKKGYEFDIEKLEQLLGVKVIPTVATKKEGVKEILNYIKEFANGNYAVVQQKINYGEDIENSIKIIEDELRVKNPALLNEYPSRWLAIKLLEEDELVLKETGIKKDESFLKKAKQHFVSAHNKDIESILADIRYGIASGVTRDVFRKREVRRLDLTEKIDSVVLNRYLGIPIFLLAMWLVFKIAFDFSTPLSDWIDSTVSGPVTKWSNFVLKSVGSPEWLVSLFTEGVIAGVGAVLVFVPVIAMIMLIITLLEGSGYMARVAFVMDRLMHSIGLHGKSFIPMLLGFGCNVPSIYATRVLETERDRKLTAMLVPLMSCGARLPVYVIFIGAFFTQNAPTVLWSLYVLGIFMAVLLGFVLKKTFFKGFAPVFIMELPPYRVPVFRDLMVHTWQKLKHFVIKAGTYIFAASVIMWFMLNTPYGVEKENSVLGRVGKTISPVFAPLGFGTWEASSSLVAGLIAKEVVVSTMAQIYVGENEGEKKKALEEGTSETPQKEEAKGFFEDLKDTVMSFAVSIKDAFLSLFSGFGIQSLSTVEGEEQRPLQSKLQGIFTPLTAYAFLVFVLLYWPCVVVGIAMKHEFGSWKLYGQALLIHSVMAWFVAFIIYHGGKILGF
The following text describes a protein:
Function:
May be involved in the final steps of mitochondrial differentiation within the flagellum.
Subcellular Localization:
Nucleus. Mitochondrion. Note=Predominantly nuclear. Some fraction is associated with mitochondria.
Sequence:
MFKRTALILRRCFQPTFIRPHHINVLENFKEADDLPNQGQAKFVDVSIHDPQHIRSALVSPMQRKFLQDLEQQQTVRIKWFKEGNQDELENMKNECRRLALEIIMAAKGGDIKKACKELAEKEKCKQIELKKKCKELEKKTKCAKKDPCKKKDPCKKKDPCKKKDPCKKKDPCKKKDPCKKKDPCKKKDPCKKKGGDLKKKCKKLAEKEKCKKLAKKEKMKKLQKKCKKMAQKEKCKKMAKKDKCKKK
The following text describes a protein:
Function:
May negatively regulate the ATPase activity of VCP, an ATP-driven segregase that associates with different cofactors to control a wide variety of cellular processes. As a cofactor of VCP, it may play a role in the transport of CAV1 to lysosomes for degradation. It may also play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Together with VCP and other cofactors, it may play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes.
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MSKIKKFFSRKKAEAAFKLNLTGSGMGTGHKLNSPKQETPSSSSRQKYEAYVPPKRNEISNEARAAASAALARIDKKTSREFNTSLSAVKAQAKRELEAERRQREEAMGTPSTTSTSTSASGGDTRNLACEGVFFRCPLISEEILPKSVWKVRIKEFLYQQLEADRGLTACLIIHNCNVKEKADECIATLIRYLENLIKNPEEEKFCKIRMSNKIFSEKVRYVEGALDVLQAAGFNEVQIDGEPFLLWTKEQTEKDLDLPTLVEALKSSEIIPLELDRNIKVLLPSQACRVALPDEFYRLSPEEIKKEQQLRSEAIAQSQMLRTKAMREREEQRNLRMYRYALVRVKFPNGLFIQGTFNVYEKISDVFEFVQSCLADESLDFSLVSNSDGKLGDEDLEKTLYDCKLIPNTLLLFSANDTPAPLQTDINYLKEDLLMLVQAM
The following text describes a protein:
Function:
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Subcellular Localization:
Nucleus.
Sequence:
MQKRRTKESRDNEGAVGWTRASRELRLLCLTTDVNARHGPPCAKPARIIASFAAPVAAAYNVSFTALLPHITVTFTFTVAAHPAARSLSFASAAMSFLKANSASRVNAPSPTPSNTSANGAKRKRPAEGAAAVVYSQPIDQGTGEHVYTRFTYTVNHLRDKNKWLPFDEIMNFLGVKVGDPQREQLRTLFRSESDGNRIMWNSANDTYRYKPKLDIRNPAQLKGYLQNQKSAQGLSIKDLKDGWATVADDIKGMEDKKEVLVKRAKDGVAKIVWDNDPSLMHPMDPEFMNEWHKIAIPANPDDLRATLMNVGLHAASAPRQINGGGPKQKKKRAARRGGKQTNTHMMHILKDFSGMRK
The following text describes a protein:
Function:
Required for primary cilia formation and promotes the localization of the ciliopathy protein BBS4 to both centriolar satellites and cilia.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, cilium basal body.
Sequence:
MAADESSQNTLRLQFKAMQEMQHKRLQKQMEKKREKELSLKSRADDQEEPLEVSDGLSLLHAGEPNSKNSFEKRVLEDEIEHLRNELRETVDENGRLYKLLKERDFEIKHLKKKIEEDRFAFTGTAGVAGDVVATKIVELSKKNRLLMAESEGAKTRVKQLTNRIQELERELQTALTRLSAKGATDAGAKPPRAQMGDRALLETPEVKALQDRLVATNLKMSDLRNQIQSVKQELRMAQKVLAREVGEDINVQQLLSSPGTWRGRAQQILVLQSKVQELEKQLGQARSQSAGTASDELSVYPDPRKLSAQEKNLLRIRSLEREKQEGLEKLASERDVLQRELEELKKKFEGMRSRNKLLSSEMKTLKSQMGTLVEKGRHDDELIDALMDQLKQLQEILGSLSLQEEKTRVSQHHLDQQLNSEAQRSNSLVAQLQAMVAEREAKVRQLEMEIGQLNVHYLRNKGVGEGSSGREVSPAYTQFLEDPGLTKSPASAGDHVGRLGSSRSVTSLGHTLVESALTRPSLPSPHRTSPRFSDSPEQKGWQAQVSEIKALWQAAEVERDRLTEFVTVLQKRVEESNSKLLESERKLQEERHRTVVLEQHLEKIRLEPGKASASQRAAPRTKTGLPTSNNRHNPTGSEKKDPSFAQLSDVPVESQMEELTTRLAIQVEENEMLKAALGSALRGKEEDFRMYHEILGQVKSVFLQALRQQKTGKQ
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MAEKFDHLEEHLEKFVENIRQLGIIVSDFQPSSQAGLNQKLNFIVTGLQDIDKCRQQLHDITVPLEVFEYIDQGRNPQLYTKECLERALAKNEQVKGKIDTMKKFKSLLIQELSKVFPEDMAKYRSIRGEDHPPS
The following text describes a protein:
Function:
Positive regulator required for the expression of xapA and xapB. Binds to the inducer xanthosine.
Sequence:
MERVYRTDLKLLRYFLAVAEELHFGRAAARLNMSQPPLSIHIKELENQLGTQLFIRHSRSVVLTHAGKILMEESRRLLVNANNVLARIEQIGRGEAGRIELGVVGTAMWGRMRPVMRRFLRENPNVDVLFREKMPAMQMALLERRELDAGIWRMATEPPTGFTSLRLHESAFLVAMPEEHHLSSFSTVPLEALRDEYFVTMPPVYTDWDFLQRVCQQVGFSPVVIREVNEPQTVLAMVSMGIGITLIADSYAQMNWPGVIFRPLKQRIPADLYIVYETQQVTPAMVKLLAALTQ
The following text describes a protein:
Function:
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MNGKEMKTERKILMAIPVHFLLIFALLLQESYGKEFHIRNLECFNDYDSELMCSWEVANSSSNCSADFQLKYETQSVQQNVCIPQNRQHGGAVVPNQCVCTMSGFYIVALTNFIINLESNGTSVQRGVFPALDTAIPKVPRSITVTSGNEDDINVTWDNGYSGSKDIFLSTYLMYNIQITCKQDPTLFESMNVTIRSCSINKRYFKSGCDYEVKVRSKFTFGENGVQSFPWSDWSSAIEWHNDYSPSFDYIPSIVIPVCCFLLFLLILLCYCIINICKKKWWQNIPDPAKSSLHLIRRHMSQETAVKSDENANIYPPSNKQENAKRICTNWFNKLFFKNHHKKHLSQDCTSKRYEHICRTEGTEYSVLVPEVSVVDTATVESHLPESRKNSVYETKDIIEDKDEKQPFFDPSIDQMFQDIIDDSPFKAHGLSTTRDTLKNSNNNILPVFAFFEDHPAPLEVIQESPDRSYPCDNSETDLPTKSDHCLFSGMDHCSADQQDSLCFVPQESLYQASETKLDNGYANNGCQANTYCDSGYSSFANAVSGSEMYSVSSEYSTDKDNELSNTSSCLSRSAFGSSNSSLHSDTTDRSVYYNRQSRFFLPDTSCDTSSMNVELTLTRISEDYNTSPKEERELSSSMNICAVSNYQTFADAIQQDGTSVNHPSETLDSSVLESAYKSFESLLNQNTPEAESDTESCLCALDMGVQKEEMTQITAQNTGTNEFDNMKNTGGQTKIDFAEAPAHEITFGFLNLLSTENCLDSGCKESTEDKQPFPPKDSSDQTQDNPIKAEDIKNDFSLIYKGDTNCHLPFAWTHGLSEQWKDLTNMYGPDFPQSSPVDKIDRIIRGSHSNHTDHGKSTVTETDIGIFPHQPAFSDHNNASDSQTMKFANMSYFVPLYNELKTKRNDTQDDLATLSDHTPEHPKNHENDGCSYMQISLPVGLDLYCREGSRVML
The following text describes a protein:
Function:
Involved in copper tolerance.
Miscellaneous:
MISCELLANEOUS: Restores the copper-resistant phenotype in the R.gelatinosus deletion mutant under anaerobiosis.
Subcellular Localization:
Periplasm.
Sequence:
MFPRRLLPASLIVLGVLFGASAQASPAHGQAFGKPAQAAQASRSIEVVLGDMYFKPRAIEVKAGETVRFVLKNEGKLLHEFNLGDAAMHAEHQKEMLEMQQSGMLTPTGMASMDHSQMGHGMADMDHGRMMKHDDPNSVLVEPGKSAELTWTFTKATRLEFACNIPGHYQAGMVGQLTVQP
The following text describes a protein:
Function:
Toxic component of a type II toxin-antitoxin (TA) system. Its cognate antitoxin is RelB (By similarity).
Sequence:
MSEEKPLKVSYSKQFVRDLTDLAKRSPNVLIGSKYITAIHCLLNRLPLPENYQDHALVGEWKGYRDCHIQGDLVLIYQYVIQDEFDELKFSRLNIHSQTALK
The following text describes a protein:
Function:
Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.
Subcellular Localization:
Cytoplasm.
Sequence:
MKKKIKEVIVVEGKDDISAVKNAVDAEVFQVNGHAVRKNKSIEILKLAYENKGLIILTDPDYAGEEIRKYLCKHFPNAKNAYISRVSGTKDGDIGVENASPEDIITALEKARFSLDNSVNIFNLDLMMDYNLIGKDNSADLRSLLGAELGIGYSNGKQFMAKLNRYGISLEEFKKAYEKINMK
The following text describes a protein:
Function:
Plays a role in the modulation of host cell cycle. Induces a cytoplasmic sequestration of host RB1 at the mitochondrial membrane.
Subcellular Localization:
Host mitochondrion membrane.
Sequence:
MHAELAEVAAAVSAAACIVGLRHARPGCARAFVAGALVSSVGYTCFPAIRHCVHMAARYLSYLCFVRGGATACVHSVADEAVQELVDSLHRVLAERDQCVLGSVELVQGSEPLVLGLPQAPVLCVPEPSGAVDPECVEVDLYCHENLRYESDVSEDEDKDDACDEGISLARQTLLDLLACSEDASGFSPPEDSFSSLLETGELYDEVLDASLARAEA
The following text describes a protein:
Function:
Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.
Sequence:
DIKLSKALSYICRHGAAKEGLQMNFGGLIFVDEILKLRQFCQFTEEDVRRVVKDNDKQRFVLATDQDSGRLQVAASQGHTMEVEGLDLSPITDKDIDKYPTVIHGTYLNSWQSIKKQKLRPFLRSLPGPTRLKIQDGARSPNVDGFRNNNTDFCFVCLFLDGYEFFTSTNNVILCPGNVDGLLPPCYFDQVIQLK
The following text describes a protein:
Function:
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. The condensin complex probably also plays a role during interphase.
Miscellaneous:
MISCELLANEOUS: Present with 704 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Cytoplasm. Chromosome. Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, condensin associates with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.
Sequence:
MTTQLRYENNDDDERVEYNLFTNRSTMMANFEEWIKMATDNKINSRNSWNFALIDYFYDLDVLKDGENNINFQKASATLDGCIKIYSSRVDSVTTETGKLLSGLAQRKTNGASNGDDSNGGNGEGLGGDSDEANIEIDPLTGMPISNDPDVNNTRRRVYNRVLETTLVEFETIKMKELDQELIIDPLFKKALVDFDEGGAKSLLLNTLNIDNTARVIFDASIKDTQNVGQGKLQRKEEELIERDSLVDDENEPSQSLISTRNDSTVNDSVISAPSMEDEILSLGMDFIKFDQIAVCEISGSIEQLRNVVEDINQAKDFIENVNNRFDNFLTEEELQAAVPDNAEDDSDGFDMGMQQELCYPDENHDNTSHDEQDDDNVNSTTGSIFEKDLMAYFDENLNRNWRGREHWKVRNFKKANLVNKESDLLEETRTTIGDTTDKNTTDDKSMDTKKKHKQKKVLEIDFFKTDDSFEDKVFASKGRTKIDMPIKNRKNDTHYLLPDDFHFSTDRITRLFIKPGQKMSLFSHRKHTRGDVSSGLFEKSTVSANHSNNDIPTIADEHFWADNYERKEQEEKEKEQSKEVGDVVGGALDNPFEDDMDGVDFNQAFEGTDDNEEASVKLDLQDDEDHKFPIRENKVTYSRVSKKVDVRRLKKNVWRSINNLIQEHDSRKNREQSSNDSETHTEDESTKELKFSDIIQGISKMYSDDTLKDISTSFCFICLLHLANEHGLQITHTENYNDLIVNYEDLATTQAAS