lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Lipid transfer protein involved in autophagosome assembly. Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion. Binds to the ER exit site (ERES), which is the membrane source for autophagosome formation, and extracts phospholipids from the membrane source and transfers them to atg9 (atg9a or atg9b) to the IM for membrane expansion. Also regulates lipid droplets morphology and distribution within the cell.
Subcellular Localization:
Preautophagosomal structure membrane; Peripheral membrane protein. Lipid droplet. Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Localizes to endoplasmic reticulum-autophagosome contact sites.
Domain:
The chorein N-terminal domain mediates lipid transfer activity.
Sequence:
MSRWLFPWSSSIKTRACRYLLQHYLGHYLEERLSLEQLSLDLYNGSGRLTDIHLDIWSVNELLDSAGAPLEIIDGFIGSISVTIPWSALVTENCTLEVSKLQVTCRPKYRGAAQGTESQSWSSCMTTSMQLAQECLKEQPEEPSEPPQPIEGLEMFAQTIETVLRRIKVTFIDTIVRIENNPGDSNLGTALEIHIKRLDYCDEAVRDSPHTVPVDIHQPPAFIQKILQLSGVSLHYEEFKTSVQTPSPTPENPLESEPVQPSKTPSWPEEPQPAPSPIQQIGSCSGCTELTIKLKQNDLFPGPKLDIDGKIGSVHLFLTPRQISNLQEILDALSISESSAIREKLLKSRPLDLEDLKLIEQDLNQQLQSGPGSLFVPDPELVPFQTIENGDMFYSMAAMTNSMTSIRSANELSDIDLESSMYSDYSSQQIPSLTPGIMLSSPRKYGRTPFSATLPQNLHKLPGKSSHPPSMELLKPEMLLRLTLGGLTVTVPHISTYISPQEDPACPEVARHFFRELGYFKDSAFSGRDFSHLRGQFEKACHLSNIRVTAVAVQLVCEQRVGGGTHQSSVDLSCGRLEILECLRQGESTSRRTKNTEYTKLMTFCSPSTSSRPCAQIHYKRSQKTPTRSSRKKQEIKVSSEILVELEEFQTDIDLGLLDRLGSIFQNGACRESYSQNDLHMTDVPQSSEDMEIRVVASKSHICLQFPVPDLRPSLERRPWAEKAVRKDCLQMEVADLDIHSQSKTGTDEARKIEITFSDLHGVYTDGEKLNVPCIRVSKGADPLAKAGGKKFIFPSILVAILPQSKVSPWYLAQDKIDDIDHPSVESPCELKQPEPSPFSSKRTMFETEEMVIPADPNEMADFQHVTLASSQYTLEITLPRAHVFFPSKEVYESLYNRLCNDLLMWEPVPELGASISDSLLSAEPHTTSNYQQDTFRMCKSAFKLDSDSDDEDSHFYSVDEAARHRRGAQDGQSYFSASVTILKGRITAWTEAKGEGAKKLDDHHGEVVLDVENGCIFSVSKYRGKEDLSYLCIQSESVALYHKATVKDYLAPVSLEIPTFLHPTNLDPTIYLSEEGVSAQLSGARKDRNQKMLSLAVRIDLNLVKNVKEFLVALRLDGATLRHHMALPYQSWHSQILDFLDVVDEPILGYSPPAVITVLHTHLFSCAVDYRPLYLPIRVLITAETFTLSSNIVVDTSTFLLRFILDDSALYLSDKCDAEVTDLRKDYVCVLDVDLLELVITTWKGNASSKLTQPLFELRCSNNVLHIHTCADSCAMLVNLTQYVMNNGDLHCPPKPEPPTEIAGQKLQPPEGPSSLPPCLPAETAQINQGDLTDALIDTGRTGKEQPETAISVDAALLEESPVSVYLFPEEIKSGNKRQTTSPSPPPLTEGRVSQESLGLSDTSGDSELTDTDDFCILDAPGIGVPPKDGEPVVRKLVDSPIAVRDGHFSRPLGSTDLLKPPAKFPVPETRIVLREISVVWHLYGGKDFGSSRPNSARAQSPRSRTSFHNARGSPSRSSVTNRPQNTWRTQGGNGRIHDILMEIQLTKVSFQHESYPEPLADGEEKLHTGDLDELPLARQVFIVQELEIRDRLASSHINKFLYLYTSEKMPRRAHSNMLTIKALHVRPEAGLGGPECYLRMSLMPLRLNIDQDALFFLKDFFTSLASGIQTIVPMELGSEASRLDGPAKSSSDCELEQETSQGSTEDETMSPSSSTDQPIYFREFRFTSEVPIWLDYQGKHVTTEQVGTFAGILIGLAQLNCSELKLKRLYCRHGLLGADKVVSYALNEWLTDIRKNQLPGILGGVGPMHSVVQLFHGVRDLFWLPIEQYRKDGRIIRGLQRGAASFGTSTASAALELSNRLVQAIQATAETVYDILSPTPPVSRCALDVRQSRKLRRGQQPADLREGVAKAYDTVREGVIDTAHTICEVASRGHEQKGLTGAVGGVLRQIPPTVVKPFIVATEATSNLLGGMRNQIRPDAHKEDALKWRADEGQD
The following text describes a protein:
Function:
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Miscellaneous:
MISCELLANEOUS: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.
Subcellular Localization:
Cytoplasm.
Sequence:
MIIQIEEYFIGMIFKGNQLVRNTIPLRREEIFNFMDGEVVSNPEDEHLKVAEIILKLYFAEIDDKKVRELISYKLEVPEFTKKVLDIVKDIEFGKTLTYGDIAKKLNTSPRAVGMALKRNPLPLIIPCHRVVAKNSLGGYSYGLDKKKFILERERLNMVSFKFNKVY
The following text describes a protein:
Function:
Major hyphal cell wall protein which plays a role of adhesin and is required for mating, normal hyphal development, cell-to-cell adhesive functions necessary for biofilm integrity, attachment to host, and virulence. Promotes interactions with host and bacterial molecules, thus leading to effective colonization within polymicrobial communities. Plays a crucial role in gastrointestinal colonization, in mucosal symptomatic and asymptomatic infections, in vaginitis, as well as in lethal oroesophageal candidiasis, caused by the combined action of fungal virulence factors and host inflammatory responses when protective immunity is absent.
Miscellaneous:
MISCELLANEOUS: As a major cell surface protein expressed during infection, HWP1 detection can be used for diagnosis of invasive candidiasis. HWP1 epitopes can also be used to develop vaccines for protection against candidiasis.
Subcellular Localization:
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=Hyphal surface. Localizes to the a/a Portion of the conjugation bridge during mating.
Sequence:
MRLSTAQLIAIAYYMLSIGATVPQVDGQGETEEALIQKRSYDYYQEPCDDYPQQQQQQEPCDYPQQQQQEEPCDYPQQQPQEPCDYPQQPQEPCDYPQQPQEPCDYPQQPQEPCDNPPQPDVPCDNPPQPDVPCDNPPQPDVPCDNPPQPDVPCDNPPQPDQPDDNPPIPNIPTDWIPNIPTDWIPDIPEKPTTPATTPNIPATTTTSESSSSSSSSSSSTTPKTSASTTPESSVPATTPNTSVPTTSSESTTPATSPESSVPVTSGSSILATTSESSSAPATTPNTSVPTTTTEAKSSSTPLTTTTEHDTTVVTVTSCSNSVCTESEVTTGVIVITSKDTIYTTYCPLTETTPVSTAPATETPTGTVSTSTEQSTTVITVTSCSESSCTESEVTTGVVVVTSEETVYTTFCPLTENTPGTDSTPEASIPPMETIPAGSEPSMPAGETSPAVPKSDVPATESAPVPEMTPAGSQPSIPAGETSPAVPKSDVSATESAPAPEMTPAGTETKPAAPKSSAPATEPSPVAPGTESAPAGPGASSSPKSSVLASETSPIAPGAETAPAGSSGAITIPESSAVVSTTEGAIPTTLESVPLMQPSANYSSVAPISTFEGAGNNMRLTFGAAIIGIAAFLI
The following text describes a protein:
Function:
Promotes the assembly and stability of microtubules.
Subcellular Localization:
Cytoplasm, cytoskeleton, spindle. Note=Localizes to the microtubules throughout mitosis.
Sequence:
MADPTFAATSSSTSFRGLHERLVAMTQELAEERRHKRGINSSAGANKRSSSTPDGSVLKNDVKQQLAKERREQQKRQQEANKEKQLLEKEQKAKLQYEKQLEEKHRKLKEQKEKDQRRQASAEEKRKQKQAEDTEKFKAVVSRTLERCNRIDQRQKRWSWEGGVMNADKSGKLENKRSSSLSRKDNRLHPRGDMQHVDNTPGMTKYVFRYVTAPVFSSDEIKSSAMFCKPSAKTPVAAKLEKITTKKLDASLRGHVEGLSMMNIEIPPKITIEVPSPPKLEESSEADAEVRLQTMDDISKVKEDASQKVDIKVPTDENIARHPKPNVEELSPVSVDTSSSVELSSIVSVNSSPSLSTGSFSFGSVEISPVVSIDASLETNIDTSPELSMDSGNTKVASEIKTEAPLQARGESRLEASVEGQPEANVEGSPKNPEIDKRNINLTTKKQPLCHIPCYRWPSSSALGCRPPSPLKALQTRKIRPPSPIPVSSKLSTKTSLSYKITPVQNVLYVPNSLGVIATKKETIQKYPIKKEFGNRSMPSAEAIKKAFIQIRHAAYEQSKNEKERLQKEETKQRIARKPEIMAEKLDKVPAEGSLPCQDEQQDKNPTKTFLESPEVQKAELQKGDSAMMKSRDSAEQRKKEQENILQHWQERLERRKASEISFSSEDEADDEGESEDSLEIFPSGGKMLSMKLKKFHKYAKTKPQKLVFLQSGTDEVDTNKNVYFNGDMKAVKQKDPKYSMIQGKGSKLSAKKPPTRPIRSRKTKEGSTAIRPTQSASSNPNHKWVCDKVIDFNQTPFLKTTLTKSNKESPADSKIACQGPQAHLDHRKRTKSVSVPLTNVLSHLHITGRASNLEHPFASVYSRLAFGKEAEESDV
The following text describes a protein:
Function:
Acts as a negative regulator of abscisic acid (ABA) response.
Subcellular Localization:
Nucleus.
Sequence:
MAPGAGSSSSARRGRRVAAAEPPRRALRMRASSPMYYTSDDEDLPEIVLTPPAPAPPRTGTRSLRMHASPPDYGRRRTNRPRRVARTRSPPVVQEAEREPPAPQQPAAVVVERVFYMVGSPPDVITATGEGPGGRTVAGFRCRRLTSTRTLVDGEDAAARAAAISGARALVMCSCHGAPFTHAEFLLHAGGTDLGRNVTGYPWLGDEMELTPPGAGGPHL
The following text describes a protein:
Function:
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type.
Sequence:
MLHLLALALLLSLVSAAPGQALQRAGIVGGQEAPGSRWPWQVSLRVSRRYWRHHCGGSLIHPQWVLTAAHCVGPEVHGPSYFRVQLREQHLYYQDQLLPISRIIPHPNYYSVKNGADIALLELDKLVNISWHVQPVTLPPESETFPPGTQCWVTGWGNVDNGRRLPPPFPLKQVKVPVVENSVCDRKYHSGLSTGDNVPIVREDMLCAGDSGRNFCQGDSGGPLVCKVNGTWLQAGVVSWGDGCAKPNRPGIYTRVTSYLDWIHQYVPQGP
The following text describes a protein:
Function:
Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.
Subcellular Localization:
Cytoplasm.
Sequence:
MRLKLKSTNGVSTITLDDSKKLFKDFLIDIQQDTQLHQDTSESVSTIKLGFPPKPIDLSYGLETTLSDKNIKDGDQLLIEFTSFKRKSVSEPPLSPQPSEKKPNLRDDIPSTFIESLNKYLILRNIPDDNSCLFNSISYAISGYDSFKNISPPEELRKVVVNYIEKDPELYSDLILGRPREEYCRWIIKKDSWGGAIELGILADWFNVRIVCIDIESGNFIRFENEKDHPEKFIILIYSGIHYDVLATNDELSTENKDTDVAQWSTGDVQQEEDILAASQKLCKLLQSKDYATNTTTFRVRCLDCYSVLVGEMGASKHAEETGHLNFGEVKKS
The following text describes a protein:
Function:
Lectin involved in innate immunity. Agglutinates all types of human erythrocytes, Gram-positive and Gram-negative bacteria. Has a stronger agglutinating activity towards Gram-negative bacteria than towards Gram-positive bacteria. Specifically recognizes acetyl group-containing substances on agglutinated cells. The hemagglutinating activity was inhibited by EDTA, acetyl group-containing mono- and disaccharides, N-acetyl derivatives of amino acids, other acetyl group-containing substances, propionamide and benzamide. Enhances the antimicrobial activity of big defensin against Gram-positive bacteria but not against Gram-negative bacteria.
Sequence:
MTINVYSVFSCLVVVLFSTPKVHGVEQNDSHPSLTGFGYEFITAKLEYLQYKLIAMELAMKEDRETIEQKLAHQETLMDELLWTIDQKQSEVTGAISQLSQAIGHNLTALKTQSCKMLSQQEACANHEQMRNEIQMLASKEDRGQFKGNFWSTSTKTPVRSCKEEPSKQSGKYLIQPTENDEPFQGYCDQTTFGGGWLVIQHRFNGSLNFYRNWVEYRNRFGSVDGEFWLGLERLHWLTSARSHELLVELKDFSGNYIYARYSEFAIGSEAEQYPLAKLGSYIGTAGDSLHHHKGMKFSTKDRDNDSTGGNCATEYEGAWWYKECHYSNLNGVYMDKVDPKAICWYHYKSSYQGLAYSRMLIRET
The following text describes a protein:
Function:
Acts as a methyl group carrier in the anaerobic acetyl-CoA pathway (Wood-Ljungdahl pathway) of carbon monoxide and carbon dioxide fixation.
Sequence:
MAVQILRDRSRAAVQKVVLGATKDQGGTRSHTIVVGGDAALPFHHFEGEIVNRPVIGMEVQDIVPDWPDVLKDPFTDVINEPGRWAQKCVAEYGADLIYLKLDGADPEGANHSVDQCVATVKEVLQAVGVPLVVVGCGDVEKDHEVLEAVAEAAAGENLLLGNAEQENYKSLTAACMVHKHNIIARSPLDINICKQLNILINEMNLPLDHIVIDPSIGGLGYGIEYSFSIMERIRLGALQGDKMLSMPVICTVGYEAWRAKEASAPVSEYPGWGKETERGILWEAVTATALLQAGAHILLMRHPEAVARVKENIDQLMVSNAY
The following text describes a protein:
Function:
Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters.
Subcellular Localization:
Nucleus.
Sequence:
MENNHQQSAEPLYPGYPFHQMLMLQQHEQLQLQQQQQVEQQMRIFWNCQREEIEELDDFKHHQFPISRIKRIIKSENNVLKVSAETPILFSKACELFVLELTLRSWFHAQENNRGTLKKTDFAAAIRRTEIFDFLADVVPADEINEVATGFGPGMVGPTAGGGFPYFYPPMGQLAMPGVMLGGPAMPGVMPGGLAMPGPMLGGPAMPEVMIGGPAMPVVAPSVYVQPPLQAWQPAGDNSNAGGGNGGQGNFGP
The following text describes a protein:
Function:
Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-).
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Membrane raft. Golgi apparatus. Note=Secreted forms may arise by cleavage of the GPI anchor.
Domain:
The C-terminal leucine-rich repeat (LRR) region is required for responses to smooth LPS.
Sequence:
MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIHAGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKELTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQAHSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGVCAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLRVLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVGVSGTLVLLQGARGFA
The following text describes a protein:
Function:
Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Multi-pass membrane protein. Note=Localized in the Golgi in the absence of bound proteins with the sequence motif K-D-E-L. Trafficks back to the endoplasmic reticulum together with cargo proteins containing the sequence motif K-D-E-L.
Domain:
Binds the C-terminal sequence motif K-D-E-L in a hydrophilic cavity between the transmembrane domains. This triggers a conformation change that exposes a Lys-rich patch on the cytosolic surface of the protein (By similarity). This patch mediates recycling from the Golgi to the endoplasmic reticulum, probably via COPI vesicles (By similarity).
Sequence:
MNVFRISGDVSHLLAIIILLLKMWKSKSCAGISGKSQLLFALVFTTRYLDLFTVFISAYNTVMKIVFLVCAYVTVYLIYGKFRKAYDSENDTFRLEFLLVPVIGLSFLENYEFTPLEILWTFSIYLESVAILPQLFMISKTGEAESITTHYLFFLGLYRVLYLANWIWRYHTEKFYDQIAVVSGVVQTIFYFDFFYLYITKVLKGKKLSLPMPV
The following text describes a protein:
Function:
May have a specific function in the mechanism or regulation of T-cell cytolytic activity.
Subcellular Localization:
Endoplasmic reticulum.
Sequence:
MAPTVHLSCLLALLVAGLAQGIKDSLRGQDPGPQPLELKEVFRLFQMQYNRSYPNPAEEEFVQLYGSQVAGEALGVSRKVGSEEWGESEPQTCDWRKVGTISPVRDQRNCNCCWAMAAAGNIEALWAIKFRHFVEVSVQQLLDCDRCGNGCRGGFVWDAFLTVLNNSGLASEKDYPFNGSGKTHRCLAKKYKKVAWIQDFIILQACEQSMARHLATEGPITVTINMTLLQQYQKGVIKATPTTCDPTQVDHSVLLVGFGKTKLVEGRQGKAASFGSYARPRRSMAYWILKNSWGPQWGEEGYFRLHRGSNTCGITKFPVTARVDKPKKQHQVSCPP
The following text describes a protein:
Function:
Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.
Sequence:
MQRDTSLRDPFATEDESSASEIGRAPERRLRIPQNQLRNADERCEIRSPQPVPGPGLPRSIAVRTETAATSKDAPAPAPSLRLSLGLPRSRTKAHSGQTSDATNITSTARQADDAVRNTDSDALLSRLSALKLGYLPSEPFTQEFSSTLPSNGGHPTGRSGFPQPHHPGSSIRRSPLINIGTYLRCSTIDAEVESFLRQGCEQKQIISVGAGSDSRYWRIMADTDLSRRLHHYVEIDFEENTSQKLSRILKSPILRASLDTNSSVYGVPLSHLSQFSLGVPCHTGSESRQFDVIRSSKYSLLAADVRSLHPDTPSAERIDLEHLLGPASTGLDSTLPTLILFECVLAYIAPDRADWLIRHLGQRFAAVQALSYDIALAGDAHPSAKAVACVSSESESSECGQTVGTADSAISTSTTVASPAPPSRFGRVMLQNLEMRKLSLPGARAYPTIHAQSQRFAQAWSDSQALQIETSGRSLFSIWSDLGAEQRSRLSRLEGLDEVEEIDMLLQHYCIVQARRQRP
The following text describes a protein:
Function:
Polycomb group (PcG) protein. Involved in flowering processes by repressing unknown target genes and preventing reproductive development. Participates in polycomb group (PcG) protein complex-mediated (probably in complex with EMF1) silencing of the flower homeotic genes AGAMOUS (AG), PISTILLATA (PI), and APETALA3 (AP3), as well as of some regulatory genes such as ABSCISIC ACID INSENSITIVE3 (ABI3), LONG VEGETATIVE PHASE1 (LOV1), and FLOWERING LOCUS C (FLC) during vegetative development, by mediating trimethylation of histone 3 lysine 27 on the AG chromatin (H3K27me3). PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility.
Subcellular Localization:
Nucleus.
Sequence:
MPGIPLVSRETSSCSRSTEQMCHEDSRLRISEEEEIAAEESLAAYCKPVELYNIIQRRAIRNPLFLQRCLHYKIEAKHKRRIQMTVFLSGAIDAGVQTQKLFPLYILLARLVSPKPVAEYSAVYRFSRACILTGGLGVDGVSQAQANFLLPDMNRLALEAKSGSLAILFISFAGAQNSQFGIDSGKIHSGNIGGHCLWSKIPLQSLYASWQKSPNMDLGQRVDTVSLVEMQPCFIKLKSMSEEKCVSIQVPSNPLTSSSPQQVQVTISAEEVGSTEKSPYSSFSYNDISSSSLLQIIRLRTGNVVFNYRYYNNKLQKTEVTEDFSCPFCLVKCASFKGLRYHLPSTHDLLNFEFWVTEEFQAVNVSLKTETMISKVNEDDVDPKQQTFFFSSKKFRRRRQKSQVRSSRQGPHLGLGCEVLDKTDDAHSVRSEKSRIPPGKHYERIGGAESGQRVPPGTSPADVQSCGDPDYVQSIAGSTMLQFAKTRKISIERSDLRNRSLLQKRQFFHSHRAQPMALEQVLSDRDSEDEVDDDVADFEDRRMLDDFVDVTKDEKQMMHMWNSFVRKQRVLADGHIPWACEAFSRLHGPIMVRTPHLIWCWRVFMVKLWNHGLLDARTMNNCNTFLEQLQI
The following text describes a protein:
Function:
Transcriptional activator that binds to the G-box motif (5'-AACGTG-3') found in a number of promoters of jasmonate-induced genes. Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes. Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation. Acts synergistically with EOT1 in the transactivation of TPS5. Involved in type VI glandular trichome development. Involved in the activation of terpene synthases required for volatile mono- and sesquiterpenes synthesis by the glandular cells of type VI trichomes.
Subcellular Localization:
Nucleus.
Sequence:
MTDYRLWSNTNTTNTCDDTMMMDSFLSSDPSSFWPASTPNRPTPVNGVGETMPFFNQESLQQRLQALIDGARESWAYAIFWQSSVVDFASQTVLGWGDGYYKGEEDKNKRRGSSSSAANFVAEQEHRKKVLRELNSLISGVQASAGNGTDDAVDEEVTDTEWFFLISMTQSFVNGNGLPGLAMYSSSPIWVTGTEKLAASQCERARQAQGFGLQTIVCIPSANGVVELGSTELIFQSSDLMNKVKYLFNFNIDMGSVTGSGSGSGSCAVHPEPDPSALWLTDPSSSVVEPKDSLIHSSSRDVQLVYGNENSENQQQHCQGFFTKELNFSGYGFDGSSNRNKTGISCKPESREILNFGDSSKRFSGQSQLGPGPGLMEENKNKNKNKKRSLGSRGNNEEGMLSFVSGVILPTSTMGKSGDSDHSDLEASVVKEAVVEPEKKPRKRGRKPANGREEPLNHVEAERQRREKLNQRFYALRAVVPNVSKMDKASLLGDAIAYINELKSKVQNSDLDKEELRSQIECLRKELTNKGSSNYSASPPLNQDVKIVDMDIDVKVIGWDAMIRIQCSKKNHPAARLMAALKDLDLDVHHASVSVVNDLMIQQATVKMGSRLYAQEQLRIALTSKIAESR
The following text describes a protein:
Function:
Plays a role in the different steps of crossover formation during meiotic recombination. Participates in the crossover differentiation step of crossover-specific recombination intermediates through its interaction with PRR19. In addition, stimulates crossover formation through the interactions with RFC3 and RFC4 and simultaneously regulates cell-cycle progression through interactions with CDC34 and subsequent ubiquitination of WEE1. May also participates in an active deselection process that destabilizes or removes excess pre-CO intermediates.
Subcellular Localization:
Nucleus. Cytoplasm. Chromosome. Note=Shuttles between the nucleus and cytoplasm in a stage-specific manner of prophase I cells. Co-localized at crossover sites with PRR19.
Sequence:
MDGPMRPRSASLVDFQFGVVATETIEDALLHLAQQNEQAVREASGRLGRFREPQIVEFVFLLSEQWCLEKSVSYQAVEILERFMVKQAENICRQATIQPRDNKRESQNWRALKQQLVNKFTLRLVSCVQLASKLSFRNKIISNITVLNFLQALGYLHTKEELLESELDVLKSLNFRINLPTPLAYVETLLEVLGYNGCLVPAMRLHATCLTLLDLVYLLHEPIYESLLRASIENSTPSQLQGEKFTSVKEDFMLLAVGIIAASAFIQNHECWSQVVGHLQSITGIALASIAEFSYAILTHGVGANTPGRQQSIPPHLAARALKTVASSNT
The following text describes a protein:
Function:
Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSSPSESSSASEHEASDDNETQNAIREDLKGMSFEEIMKLKEELGAKVYKEAVLGSKSSRPQKPKAKTDLKRLNKNRPREMTTRRQVPFLGAEHRVERKKNVELRDPRFDEKSGTYSAETFKKNYQFVSQIRAKEVGQLKKKLDEVEDEAEKHHIKDTMQRLINKNVEDKKWHTKQKQLKKERSAIQKKHDLGQQPHYLTKKERRAKELVAQFEKLKNTGKLNKHMEKRRKKNAAKDRKRIGIE
The following text describes a protein:
Function:
Participates in the control of the reentry into the cell cycle following pheromone treatment.
Subcellular Localization:
Membrane; Single-pass type IV membrane protein.
Sequence:
MTGPGPEINKEEHPSSPGKKQITYNSIPKNANLIDGSTNSSKRPIEKYDKRIADPTKSYFPHSISRTPRRKYTYILVLTSLNGTFESKHVVIPFKPDGLKLGRPVANSNSSSSSSLRGGKRVDSHTFSQVRSDNGNFDSRVLSRNHALLSCDPLTGKVYIRDLKSSNGTFINGQRIGSNDVEIKVGDVIDLGTDIDTKIEHRKISATVEELFVQPLLESPIFENEDSDDCHTITEKEEAAAITSHIYGDSNNLELEEVILGSDTEILSGIFINNCIGTSPTLSNIIKTLAMEIPFSKCDNFKLQSMENFLINYTTHLEYTNKLLVEKNDQQLVKLQNGLRRKLSGKYEKIIEQNRNQVKQLERDHMFFKKSFEVKKRRNNEKQKSMEREIEDLKTRLEVERYKNSQMMKKNKQKEQELSTASKKKTTEHDTRGVPGMNPKGTDKFSIKNTLCNHFTLLTFGTISIGIIAIVFKILSPN
The following text describes a protein:
Function:
Required for normal meiotic chromosome synapsis. May be involved in the formation of meiotic double-strand breaks (DSBs) in spermatocytes.
Sequence:
MTAADHPAFGRDEEAALLLERTHHRHDPRWLLPVSPHVCMACALELLPEPGVSLVRKKHVVFCFQDALVRHTSLVAQLVAQDQRVCIHFVRVLFGLLNSVEDGSMADLCIEVLVQLTTQPNMEQTIRCLMNECHRELCNLRSMGGSLATTTLLGKLVDTIPGLADELVMEHGNLMEHLLRGLVYPNEGVQASICYLYGKLYSSPTAAEMLSGHFREKLCALFLSTLDSAQTKDLQINCLGLLRQLLKYDLFVSLIMNKSVPVEGAESVERPSRETSLPLVLKKFLLSRDEILQVASSHCITAVLVHSPAKHAVAFIHADIPEFLFEHLSSSSEILVWSSYNCLILLAEEPLFFSKCHTVYGIEAVVRSLQGSQQMTNTELHTQGLLLFKEILTRQPEEIRLFTSSALCRDASRALQEAVSSPVLAVAAEALRAISAFLRKDHQSSLPVQYRALRALLEAMLSRCMEFSQTPLNRRSLGHACSRNSEKATLRKGSFLLSTLEGFRNACRLAVEFQGEPSAQENPFTAPSAEKEDTLEAFSEYLLSACDSQCIPMVMRYSEEATHPKLMEVFLSILHSLFVIIPHMKVKFSRKLADSSFIRLTLELKARFCSGQSHSSLNQVCSSFLYYMCLNLLSAPEKTEPLSQEELSAVSEFLQHGLPHISSRTPESLAFLSDRQYVEAATRQRQYCILLLFYLAHIHDDRFVPEAELFVAVQSFLLSLQDQGECPPPVVCKASMYLLAVCGDKDSALAEAVISAIRKFLEGIPDLRGVYTHHPLLLRFFLAYPGLMSRFGHRVLELWFSWEESGYENLDDDSSPGRTVFPANLAALFRVLQSTPSILLILLDLVYSSPVDTARKVLIVLRVFLWENEDVKVGGLIRGHFLLILQRLLVEYGASTSGGNLPLLLNLLSLVQMRNESEQELDSMAMKLLHQVSMLCGKCSPAHVDILQPSFNFLYWSLHQTTPSSQKRAAAVLLSSTALLELLEKMLALTWTETGSSPRTPLLSSAWLLTASFSAQQHNGNLQVHRTLSVELNQVLKALSFPKKMSALLSAAILRFLRTALQQSFSSALVVLVPSGDQPLSTPEDAVLAPLGKSQVLALLIGLQNLLVQKDPLLSQACIGCLEALLDYLHARSPDIALHVASQPWNRFLLFTLLDAGENSFLRPEILRLMTLFVQYRSSCVLSREEVGLILQGAALVDLSALSNDTLQALHGFLLQVQSMGLLNDQHMTQTLQSSLEGLCSRTFPAQPLFQDMLCLGGVSVSQAHIRG
The following text describes a protein:
Function:
May act as a regulator of myogenesis. Promotes the repair of DNA double-strand breaks (DSBs) through the homologous recombination pathway by facilitating the recruitment of the DNA endonuclease RBBP8 to the DSBs.
Subcellular Localization:
Nucleus.
Sequence:
MTRDFKPGDLIFAKMKGYPHWPARVDELPDGAVKPPTNKMPIFFFGTHETAFLGPKDIFPYDENKEKYAKPNKRKGFNEGLWEIENNPKVKFSTPQNILAITNAALREAAEAQMQEDLEENEEKVTKRRKSTTSKILGKHSDSSSSGLESPEKDMNATKEDASISDQLGSEDAGIIKDSPVVVKGRRGRKRKVDILAESAQEIAAAPVSPPVQSPKRGRPGKTRPGRNEPWKTFAGATSWHSLATGEVKVPKPRGRPRLIKPPPSPERGITSEEDQSKKKSPERKPKKQTLQKKDEVLKDEEETPRKETDKKEARVEAETKKKVAAKTDSPAQSDSDDDEQEDGKKGKAGKLSQVAQKRSLKAQQEKDIPDKKRKQEETVDMESQSKDEVKKIDVKKLDKKKETSTDARLQRIHAEIKSSLKIDHLDVNRCISALDELASLQVSMQQAQKHTDMITTLKKIRRFKASQVIMDKATMLYNKFKNMFLVGEGDSVITQVLNKSLAEQKQHEEANKAKEPGKRGPHKKVEKEQNPDTNTFNGDQESQDQAQQNGDSSEETEEKEDNTLKRSVSASKGNEASKQTRDDSAPDN
The following text describes a protein:
Function:
Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.
Subcellular Localization:
Endoplasmic reticulum.
Sequence:
MPANERAVFVTVGTTKFETLVERVDSLELLRALKDKGYTKLVIQKGNGSYCPSVIVPKGQTKGTTEGVDVEYFDYSPSLAAYITSAALVISHAGSGSIFETLTAGVPLIVVPNPLLMDNHQVELGEQLAAMGHLVSAAPEQLLAAVRSFDPARLKPYVKGSAAGMAAAIDKQLGFTP
The following text describes a protein:
Function:
Catalyzes the dephosphorylation of D,L-glyceraldehyde 3-phosphate in vitro.
Sequence:
MIKGILFDLDDTLYNSSEFVEIARREAVKSMIDAGLNIDFEEAMNILNKIIKDKGSNYGKHFDDLVKAVLGKYDPKIITTGIITYHNVKVALLRPYPHTIKTLMELKAMGLKLGVITDGLTIKQWEKLIRLGIHPFFDDVITSEEFGLGKPHLEFFKYGLKRMGLKAEETVYVGDRVDKDIKPAKELGMITVRILKGKYKDMEDDEYSDYTINSLQELVDIVKNLKKD
The following text describes a protein:
Function:
Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.
Subcellular Localization:
Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MICTLLRAVRCTERLHGCPGKPWFLPHSVPHRACSQTEPRWRWGLQEQNTTARPRCIWGVTQRSIWTQVRSPQSAKEDGSKQVSVHRSQGGETVLSTSQKVKEAGRDFTYLIVVLIGISITGGLFYTIFRELFSSSSPNKIYGKALEKCRSHPEVISVFGEPVKGYGEVTRRGRRQLVSFIEYKKDGLKHMRVKFYIQGSEPGKQGTVHLEVKENPESGEYEFRYIFVELEPYSRTIVVEDNRS
The following text describes a protein:
Function:
RNA-binding protein required for assembly of the holoenzyme telomerase ribonucleoprotein (RNP) complex. Specifically binds telomerase RNA ter1 and promotes assembly of ter1 with catalytic subunit trt1. Telomerase is a ribonucleoprotein enzyme essential that copies new telomeric repeats onto chromosome ends and functions to maintain cell division.
Subcellular Localization:
Chromosome, telomere. Nucleus. Cytoplasm.
Sequence:
MFVPRQLNVRKIKAFTGKENNSIADGNNNKLKDEHYKHNEASKEPSHSISGGLMLNQQDRQLIEPLNPDFLSAVDSILEIYFHRERQKEKVHLAFLIQQDDFWKGIRPNPTQNNLKYALSYVTNALFHFDNSSHMVIRNENIVLPLDIPLYDRIIYVEPVPATLSNKSLLLAGKLRKYLKEFLPYVDAIGTPEGYAFVILYKKVDQSALSKLPVPPGWVLLTRKEWTNREEKYFENQLHLVKASSSDVSNSSNSFPENRYPKLTKVEKQMTKSVSKTSQTDKDEDNLDFTKNLLTRIKNLHPLTNKSTIHSLLSYVFSRQTQNIACEPMYIDYRKDETEAIIRWKTPLHAETCINAFRTQERKQNSHDDIRAHRKKGSSRPFLIAELITGEEEKNYWRMLKK