lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MGDDLRLDFDKLPIKRLEAIDEAGNEHYPPDGSSEAQRLAAIRRIDFSWVVERDAKKAKKAAADDAARKAWPWQGLHESLQLAQQELTVILDLISTVEANDTVAVAATISKPKPLPDEVLADMAVSAATKLQRLRHLGRYFKQSAKTMGQQFQKEARFYGSLIRLQQNWKVKRQLGNAPGSNSFMFDVVDTSQLDTAEMPRLSSLSLVPIDQDSSGTLSVQIPQKSCRFLSLQFHGDSASGVESYTCKTKGVSSTTCSAAEDDASENDDVNKSVKQAHSILRNIHKSIFEEQVFDMVIRETFVQTQGVNVTGMCEDFLQLAIGQESLLCLSLANSGQDSDSEMAGHEEHTNSEANLVLATTNGKQEPLKATPQGFLTRKVWRFTCYICSMTTFLRKSGRNIVILFATRVLLTLQSLQVSRVPYLHLQSLPTWHSRTSSWSICLRVPQPILAADRLTKPSDNGEPKYKSSRRQFNTKIVLKDGQISLLGEGSPSIAGSLTRKPSDGYLINSYSCDLEDLPTMVLQQVASQVINWLHEEAQVLGMSVTRDFLGLYFDLDHGDTTLGLVGHIDPDDAYGCVSWYLTVDHLAEEDGKAPATDDPWAEEKCRFLGYLSLEVLHSTLMDLINLCGTAPTR
The following text describes a protein:
Function:
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42 (By similarity).
Sequence:
MFRQGSNSGNKRMTSGARLSQPIIPLSLPTASSKTLEMGRSSKTNPLNAMGLDHNIATSGGDPEYIMQLVNDVRKFSDVLLSLKEAFHSKESQECSQHVVNERLGELVHVLKAVIGKHQALNSSEILGAAGTVIAKVKGVNFKEVNNENKSTIFGEIHTSIDTLAFTFGNVVSDFLMGDVDGGSRLGYPQARRSRSFENLSEDSRGCSQNDLADHSLSPELSTVEQVDLLLLKNDSGVESALLYAKAWSKYTKDVLAWVEKRLSLDMECAKSFAKMAESAKAVASQQDFMPFRDIYVSAFKNEIEYNHVLLQTAAALQTNKFTQPLLARKNDLDKQRKEIKEQWQRELKKMNESESALKKARLLKMQKREEYEKARSSTSRTEEEQPAAGGRTLEKKRRVEEEALQKAEEAQEQYKACVADLEAKKVSLSNAKSEILAQIRKLVFQCDLTLKAVTVNWFQMQQAQTMPLSVNYQALSEQAKKYEPGQRYSEFVRSLPKERVWLESLSQDITASSKTGMSLHKRSQNSTRSSHGNLSQGSATSMDNHSADEVEGNMQPCKAKIAERRSNSSIDMQVPRTQGSQRAWSSGSAGGGGMCSDSESAGGSSESRSMDSPTASPGDFKRRLPRTPSTGTMSSADDLDEREPPSPSDTGLSEMVMETASSPGPFRNAQMSKAAHTHKLRKLRAPSKCRECDSLVVFHGAECEECSLACHKKCLETLAIQCGHKKLQGRLHLFGIDFAQVVKNSPDGIPFIIKKCTSEIESRALTIKGIYRVNGAKSRVEKLCQAFENGKDLVELSDLHPHDISNVLKLYLRQLPEPLILYRYYNDVIGLAKETQNMDKTDSAKEKSAGEQLGLSTELKRVLFKVRDLLRQLPAPHYKTLQFLITHLHRVSEQAEENKMTASNLGIIFGPTLIKPRHLEAEVSLSSLVDYPHQARMVELLIKHHQMIFDVPLSPMSPTSPTVSQASFGSSIQDKESKLSRHSRSLMDIKESAKLYKRHSSVIIPAQLMEEGKEMKTGDHRVQTSGEGSDVNGVGLTSVDSTSVFNRPGASSRMVQLRPQRAKPVSRPISMPIDRLLNERNSRNTVEHDHSPAAIEETTEPEKPTTPRHTNFYRNPFIDTQTLRRTWDRQYRHYDVTPRTAMIVANLPPSGVQKQPEISMASQSSTSRKDGTSQSGVAPISFRAARTLKPSSPGTFYRPPSGGQLKPSDLLAKSVSRAPTTTTGAIYTTAITVLTTASTSSVMTISTAVTTPPTTPTTSVTVALTSKPTFTTVSRSVSGGAGEGLSESDLLSPVTLSPPQSPGSSTEELSPTDAKPLYQRRSRRMQELEHREAHFV
The following text describes a protein:
Function:
Acts as a positive regulator of hedgehog signaling and regulates ciliary function.
Subcellular Localization:
Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Nucleus.
Sequence:
MGTSGRGNNWSHGFLEESKLDQILDSFRRLAEASFRYDGCMITHSLAGGTGSGLGSRMALELRDLYPKNYIMSCSFAPFSSGETALQNYNALLTLASLQSSADFIGVFSNDAILNTVTKQLGLDSSRNTPCVSIDTLNYWASQTLAGIMLPISPVSLDPINFCDNSLNRYTGQESNKVVVSDSVKPFSGWDLITRVTPMPSMKLAMFSSSQSIYTASKNIPKHAHTIDSWEDHFTQLHRNMSLPVGHRRNCIGAQLNIRGVQGVEFWKRWPEMQSKWLLKLGLSTPNTCLDVRMSYIYGLDMHSKQRSLDLCYNSDDIVPIVKKVYDQALHMYSQRAYVHWYERYMQSRTDEMFSESFEAVNSILDSYSTLSTNHLL
The following text describes a protein:
Function:
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.
Subcellular Localization:
Secreted.
Sequence:
MAERRAWLACVVGILVGLVVVSSGEPQPWMNVEEDPTTRAEKLMQEMTLAEKIAMLHGYSGTSQNYNYTGFVVPNDRLKIPALQLNDGPQGFRATNNGYDRTTTAWPSGLTMAASWDVAMLSKWGEGMGAEFAAKGANVQLGPGLCVARVPVNGRNFEYLSGEDPFLGYTLVQPVIQGIQSQGVIANAKHYVNNNQETKRTTVSENVDERTRFEIYYPPFEGAINADVGSFMCSYNKINSAWSCENNETLNTDLKHRLNPDNKRFWVMSDWGATHSTSIDKGLDQEMPGDSHMGDTLADMVSNGTVPMALINASVLNILTPMFSVGLFDKPNTGAFSNNVTSDAHNQLARELAGNCHVLLQNENKVLPLNAGTANTTYLIVGAQAWNQTIVAGGGSGHVDIPYMVTPLDAFKTALGFGPTRNNQAGQKDCVVENQCVIYLDGSDTDMVASTAAEVDYVLAFVATTSHEGADRANLSLAGGQDEFIIAAASHSDKVVVIVTTPGAILMPWSADVASIVVNFMPGQEGANAAADVLFGTVNPSGKLPLTMPNVENEVGFTERQYPGLDDAAEAYYDERLLIGYRWYDAHGIEPRFPFGHGLSYAAFKYDNLTVSKDEVAFKLTNIAEDYGGEVVQLYLGFPSSAGEPPKQLKGFTKVFLHAFAEAEVKLPLRSRDRSVWDASTHSWSEVSGEFQLACRGAKVTLIERTGVACAASGKAGGFLARDWCNGGPLESLARRSFDLHEQLAAAHGNPWEYRRLRTVGINVLKSAGRPSPAVPWLDGGADGKTENMGSTENTAQVTPGLFTRKMVELAQEHGARVRVETVIGLSYREGLAEVCGVQLATGEAVPADAVLLCMGPWSGQCREWVRAITAPRIGGEKAHSIVVQPGPRADIDGTAVFINYTRRGKMQNPEIYPRPDGSVYMCGGTHAHTPLPANSADVVPTEGIGAELKEIMDACSSALQDAEVTVVQACYLPMPDSGVPFIGPLQKGLFMAAGHTCWGILNGPATGEAMA
The following text describes a protein:
Function:
Sigma factors are initiation factors that promote the attachment of plastid-encoded RNA polymerase (PEP) to specific initiation sites and are then released.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MACLAPQFLWAPSAAAHVPSSSSSYSRCSALRVHCAVTSAVVVEDRTNRSAAQLKLAYAAPAIQRNLEATLASEALLNEEAVVAAAAAEAVALARAAAEAVQEVVQMVQKNNHQPVIRQKKGVDNYLANEILRTEMQSSSPDMYANNSLMEDLESYGIMASEDELDAYAQYAENIAVKSARQSERRARRTRAAIKASTTRCASQKAASSSKKKRSKGSSSSMNPLGSLWKMTGRRLLTAKEEVEFSEGIQDLLKLEAIQAELTEYNGGQPTFSQWATAAGVDEKTLRKHLNYGIYCKNRMVTSNVRLVISIAREFEGPGMDLYDLIQEGMQGLIRGAEKFDASKGFRFSTYSHWWIKQAMRKSVSEQSQIFRLPAHMVEASYRVKECTKRLRRKLRRRPTNEEIALDTGMPIKRVEAAVNLPKYSVSLDSKIGSTDMTYQEVTADPSAETAEEMLNRMSMKKDVHKALDTLTTREKQVVVLRFGLEDDRIRTLQEIGNIMGVSRERIRQIESGAFRKLRSKKRVKALKDYLVPVGNW
The following text describes a protein:
Function:
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MFQQVTRLASRRAFSSTVRRQAHYEEGVYSNIPMKIHNRRIPYAVLHFGFFALGFSLPFVAVYVQFKKAGL
The following text describes a protein:
Function:
Regulatory component of the SET1/COMPASS complex implicated in the tethering of this complex to transcriptional start sites of active genes. Facilitates histone H3 'Lys-4' methylation (H3K4me) via recruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylated C-terminal domain (CTD) of RNA polymerase II large subunit (POLR2A). Component of the PNUTS-PP1 protein phosphatase complex, a protein phosphatase 1 (PP1) complex that promotes RNA polymerase II transcription pause-release, allowing transcription elongation.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MKLTDNVLRSFRVAKVFRENSDKINCFDFSPTGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVSLSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAGINSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTALKFSNDGKLILLSTNGGFLRLVDAFKGAVMHTFGGYNNSKAVTLEASFTPDSQFIMIGSEDGKIHVWNCESGMKVAVLDGKHTGPITCLQFNPKFMTFASACSNMAFWLPTIDD
The following text describes a protein:
Function:
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function.
Sequence:
MNTMDVFGLLRLPLSTSSSLALLLLVQGAVLAQSPCEHQVAAQIQLFRSNDGEAIRAAVRTLGKLGAAAVPALMETLTDQQEDRGVRLSAAQTLGKVGSAAVPPLIAALEDPREQVRIDAAFALGQVGPVAATALTEALQAQSVILRHFAAFAFHQNPHLAAAGSQDLFEATKDEQPLVRANALRALSSIRPVVPQVVSVLLKALEERDAQVRTVAVQALGEIRLATPEILTAVNEMLLDTDERVSQSAVRTLLTLSNLP
The following text describes a protein:
Function:
Component of the p-aminobenzoyl-glutamate hydrolase multicomponent enzyme system which catalyzes the cleavage of p-aminobenzoyl-glutamate (PABA-GLU) to form p-aminobenzoate (PABA) and glutamate. AbgAB does not degrade dipeptides and the physiological role of abgABT should be clarified.
Sequence:
MQEIYRFIDDAIEADRQRYTDIADQIWDHPETRFEEFWSAEHLASALESAGFTVTRNVGNIPNAFIASFGQGKPVIALLGEYDALAGLSQQAGCAQPTSVTPGENGHGCGHNLLGTAAFAAAIAVKKWLEQYGQGGTVRFYGCPGEEGGSGKTFMVREGVFDDVDAALTWHPEAFAGMFNTRTLANIQASWRFKGIAAHAANSPHLGRSALDAVTLMTTGTNFLNEHIIEKARVHYAITNSGGISPNVVQAQAEVLYLIRAPEMTDVQHIYDRVAKIAEGAALMTETTVECRFDKACSSYLPNRTLENAMYQALSHFGTPEWNSEELAFAKQIQATLTSNDRQNSLNNIAATGGENGKVFALRHRETVLANEVAPYAATDNVLAASTDVGDVSWKLPVAQCFSPCFAVGTPLHTWQLVSQGRTSIAHKGMLLAAKTMAATTVNLFLDSGLLQECQQEHQQVTDTQPYHCPIPKNVTPSPLK
The following text describes a protein:
Function:
Likely plays only a minor role in eisosome assembly.
Miscellaneous:
MISCELLANEOUS: Present with 538 molecules/cell in log phase SD medium.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to eisosomes.
Sequence:
MIQESSPDALAAAAAIGNALSYNGRTVDKSKIPQYNQSFTSRTTSIAGINRYTMLSNSRTNSRMLLMNGNVRQYSKRTSSLPNQGHKNTSNNSAGRRQHRAHEDAETTFREFGGKQSSKVLNISSSTGQNSKSRTTSLGNSGSTIRTIKKYIPGPRGLMAVEVPVEVEPPRYSLSNRSNQRGGRAYSLPTRNNKTSLMHRNKTTKKAGSQEKKSESGGKSKNDYHGKVLSKMHTTSLKQRHNNVPLIPTTMNEETEQELQEDLHDPLEFKPMIISDDENSFIEPSVLDRSIPKKDKSGLSGREKKEEIETLLKEVHSLEEKISNIEIAKLNEEEREQSLILELRKVKLDEERRMELLKRELNIVKENADLEAQELKLIESKRKQHFHKGQEVASEVKSITIRQPTLSEPKPAYVPPEDVEKEPSTLSNQTQNIENAENIDSVDAEGNLVDPILLGSLNNSNFHMNSDNEVRCIADSNSLTGSELSDYNYIEGSATDLRATAKTSVESEIGGNQVGLKIPQDDDSEKQEERTKGKKSGLVDTNCFLVQKEDQEEALSDNEPESSEKFPSTSGIENVKLEDETGSVMDKNNGPNNDKDDDDDKDNDNDDDDDKDDDVNDDDKDENVDDDENVDDDDDDDDDDDDEYHDSYDVIMRDPVQIEQDISDVPSLKHPSEYSTETEDNKKKEQNSENAEVSQSGTNMAKYLRGANPYLTNTSSDTFSLDSENVNSKSSTDTTRVAPDLLKSSLQPQLRSDLKQSAVPSSTSSSIYSIETSPNIDSSTGKTASNTKTNSHGPPTSISKQKYDQSSSHQIPVMSPKRLDDKRKITNRSCLRTLRGSSNEATLSHNIVYPASDSSSSPPYHSKKPSNPPSSGNLASHEASKCFPKAPQASTTSRRLPDHVPLYIDKNNSALYPKEPPARKSSFEKERPAKDNLGFRSMSLREPLITKNATATAAENLDVEEKKEKGGHVSRKSWTFGLPSPLKRRTSHSTHTTNETEIVNPMTNFKNKTNENDMPILANKKSCNNDDSSPYTASSMNTNDVSEAGTEGHRFSLFGNKSQLSNRNISGGTATLESSNPDLPTALPLSVPVTIIDKNGEIHKLHNDDAAIKDKSHDRHGHSKFGRKLKKIFGRK
The following text describes a protein:
Function:
Involved in autophagy. Thought to act in autophagasome and omegasome formation.
Subcellular Localization:
Cytoplasm. Membrane; Multi-pass membrane protein. Note=Forms a reticular pattern throughout the cytoplasm.
Sequence:
MVKFQIIARDFYHGFIDSFKGITFVRRIREEEAKEVKVEPPKPVERTVLMMRREKQGIFKRPPEPPKKKDSFLKKLWQIYAMNIGFLVLWQVCILILGLFFSFFDRTDLGHNIGYILIIPIFFASRIIQALWFSDISGACMRALKLPPPPVVPFSSMLAGTLISALHQIFFLIQGMLSQYLPIPLITPVIVYLHMALLNSMYCFDYFFDGYNLSFLRRKDIFESHWPYFLGFGTPLALACSISSNMFVNSVIFALLFPFFIITSYPANWNRKYEEEIPKIAFCRISYMFTELVGKFVKSITPTNNPTAARNNAQN
The following text describes a protein:
Function:
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
Subcellular Localization:
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MASFDEGDFPAQTTHSPSQPDNFFMSDHNISEAHPPPSTQHSLNRDGDGDDDFGSENNPASPNHANGNDDALFASDGPFLRLEWRWRRKRKRRRCAIKKAFYEKREKTIETKKADNREREKSELISREVPNIDKKRGKNDPDKKPSMIVIQGPKPGKPTDLGRMRQIFLKLKTNPPPHMMPPPPPAKMPKTENLQRKQRGQKKNMLHLKQ
The following text describes a protein:
Function:
Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MTKLLQWLLAVSLIGIAWGLVTFDLLDLHLLPQYKELAWPMPVYLLVVFGCYSLATVGYRVATFNDCEDAAKELQAQIKEAKEDLRKKGLKM
The following text describes a protein:
Function:
This protein binds to 23S rRNA.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MKYAIVEISGRQFWIETGKYYDLNRIPTELEKEIILNRVLLANNDGEILIGKPYLDSVKVKGKILEHLRGRKTIVYKMRPKKKTRKKQGHRQDLTRVLIEEIKIN
The following text describes a protein:
Function:
Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
Sequence:
MNILSIGGSDPSSGAGIQSDIRVFSALGVHTLTVITAITSQNTSKFGMVEPVSSKILQKQLESVFSDFKINGVKIGMVYNSKIIKIIHQQLKKLKIPIVVDPVIRSTTGGSLIENNARKDFQKYIVPLATIITPNKKEAELLTKMKISTKNTPEKVAKEIQNMGAKNVTITGIEEKKKVSDFVLEKNSKYIISGEKIPKINHGSGCIHSAAVVYSLAKKKSIKESLYFAKKFTYKSIKNAKKIGKGIAITDIQSKNKIEDELSSAITKFIKLKGIYKNIPECQTNFVFSKQRPKSTKDVLGISGRIVKAGTNVLVAGDLKYGGSKHVATALLSMNKKYPGICSAINLKYQSTTLSKIKKSKLEVSSYDRSKEPKHVKIKGSTIRWGINSAIKNSKKIPDVIFHKGDFGKEPMIIVFGKTPENVLEKILKIKG
The following text describes a protein:
Function:
Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptive immune responses (By similarity).
Subcellular Localization:
Endoplasmic reticulum.
Sequence:
MEPLPEPASGPRPRPHRLLLLSLLLLLLPLLPAPELGPRQARAEDTDWVRLPSKCEVCKYVAVELKSAFEETGKTKEVIDTGYGILDRKASGVKYTKSDLRLIEVTETICKRLLDYSLHKERTGSNRFAKGMSETFETLHNLVHKGVKVVMDIPYELWNETSAEVADLKKQCDVLVEEFEEVIEDWYRNHQEEDLTQFLCANHVLKGKDASCLAEQWSGKKGDTAALGGKKSKKKSGRAKGLGGGSSKQRKELGDLDGDPSPEEDEGIQKASPLTHSPPDEL
The following text describes a protein:
Function:
Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MSEFRIHHDVNELLSLLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTPEDFLKKYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAAAAVGSSTTSINVPAAASKISMQELEELRKQLGSVATGSTLQQSLELKRKMLRDKQNKKNSGQHLPIFPAWVYERPALIGDFLIGAGISTDTALPIGTLPLASQESAVVEDLLYVLVGVDGRYVSAQPLAGRQSRTFLVDPNLDLSIRELVHRILPVAASYSAVTRFIEEKSSFEYGQVNHALAAAMRTLVKEHLILVSQLEQLHRQGLLSLQKLWFYIQPAMRTMDILASLATSVDKGECLGGSTLSLLHDRSFSYTGDSQAQELCLYLTKAASAPYFEVLEKWIYRGIIHDPYSEFMVEEHELRKERIQEDYNDKYWDQRYTIVQQQIPSFLQKMADKILSTGKYLNVVRECGHDVTCPVAKEIIYTLKERAYVEQIEKAFNYASKVLLDFLMEEKELVAHLRSIKRYFLMDQGDFFVHFMDLAEEELRKPVEDITPPRLEALLELALRMSTANTDPFKDDLKVRVGCSGTCQIFTQVWQKRELCHAVATSSHRGPKAALPGLQCPRDSRAVRGPRCGLWSTDAVSTTPPVTEAHLRCRHVSCRKALTRYQMLFRHMFYCKHVERQLCSVWISNKTAKQHSLHSAQWFAGAFTLRQRMLNFVQNIQYYMMFEVMEPTWHILEKNLKSASNIDDVLGHHTGFLDTCLKDCMLTNPELLKVFSKLMSVCVMFTNCMQKFTQSMKLDGELGGQTLEHSTVLGLPAGAEERARKELARKHLAEHADTVQLVSGFEATINKFDKNFSAHLLDLLARLSIYSTSDCEHGMASVISRLDFNGFYTERLERLSAERSQKATPQVPVLRGPPAPAPRVAVTAQ
The following text describes a protein:
Function:
As a component of the decapping complex, involved in the degradation of mRNAs. Promotes P-body formation. Translational repressor.
Subcellular Localization:
Cytoplasm, P-body.
Sequence:
MASSSSSSSSKAGESYIGSLISITSKYEIRYEGVLYHINPQDATIGLKNVRSYGTEGRKKDGPQIAPSDKVYEYILFRGSDIKDLQVQSPPPDQTEEQIYNDPAIIQNHSALSSSTAAGVQAQHTPALTTRAYSGALPLFQPVNHVGLTNLSQATQNAGPSLSIPKHSQGYHGISSQQSMVSSPLIVQNHMQALGLQEPPVMGLKSPSECITPESTVATNPFNPIFSSSLSPVQYATSPDTSSFLSLKTPVPSHAASLPANRLTMSSIPMTSIPMSSQDINTTETLAVADPMAMRPAQSLPYLMPSYVGSTSSSVLTPLPSLLSPHHFLQSRPPVLSSPQKLYPDQKDVAALTPLSSTSPPLLSTPASQPPLLPLPGSVQQHKYLTSKFTEEFDFEAMNEKFKKDEVWGYLGKAKQREKTEGMEDNTTDQSMVDKEAPVVVLNLDPKPAYKKDEFFDTISCNIRNQRWNGQNCFSERMKLDTETFGNLHLRPNLGYGGIGSGRGDTYHTSRGRGRGYGYRGRGRGYIGF
The following text describes a protein:
Function:
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Required for the correct development of pollen.
Subcellular Localization:
Nucleus.
Sequence:
LNCFFIFFSTFSFFFSTYYFAYSPHQLQSDFWYYRFLRSRNAYIKVEHGSETTNPEKQFYQVILFVPIRELHKARERLLRNLKNHPIESNNTQIRIERERIRSEKTVIRRLVLGLMGAAGSKLEKALGDQFPEGERYFGFENFGNTCYCNSVLQALYFCVPFREQLLEYYTSNKSVADSEENLMTCLADLFSQISSQKKKTGVIAPKRFVQRLKKQNELFRSYMHQDAHEFLNYLLNEVVDILEKEAKATTKPERETSSSSSPEKIANGPKAPLANGVHKEPVVTWVHNIFQGILTNETRCLRCETVTARDETFLDLSLDIEQNSSITSCLKNFSSTETLHAEDKFFCDKCCSLQEAQKRMKIKKPPHILVIHLKRFKYMEQLGRYKKLSYRVVFPLELKLSNTVEPYTDVEYSLFAVVVHVGSGPNHGHYVSLVKSHNHWLFFDDENVEMIEESAVQTFFGSSQEYSSNTDHGYILFYESLGPTTK
The following text describes a protein:
Function:
Trithorax group (TrxG) protein that has histone methyltransferase activity. Specifically trimethylates 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. TrxG proteins are generally required to maintain the transcriptionally active state of homeotic genes throughout development. Does not act as a coactivator required for transcriptional activation, but specifically prevents inappropriate Polycomb Group (PcG) silencing of homeotic genes in cells in which they must stay transcriptionally active.
Subcellular Localization:
Nucleus. Chromosome. Note=Localizes at the promoter of active genes.
Domain:
The SET domain is sufficient for methyltransferase activity.
Sequence:
MSCSQNETAAAKVLETQRAQESGSENEETDSITDQSSQSKSIKSATQFSVQRSDTDGLRMRISAIRPTLGVVATKKPPKSRKMSTQDTESGCSEAKNRAVSKKVKVKRKKLASSSGISKSDKVSKSKKSQISAFSSDSEDDLPLKVHQQRAPRVLLSAIIQAAQSASKPTLDIGISSSDNELPNLVQAAIKRVESDTEDTTVEGSFRKAAKDKNLPQYQSTLLQDFMEKTQMLGQTVNAKLAEEKVAKAKEETLVQTAVPRKRRGRPKKVVPTVPAPGNSGPAINESADSGVISTTSTTQSTTPSPKMQNENAVPTGSLPIASSSKPKIDMAYLDKRMYATERVLYPPPRSKRRQNNKKTACSSSNKEELQLDPLWREIDVNKKFRLRSMSVGAASGTGASTTICSKVLAAKSGYVSDYGSVRHQRSSHNHNSGYKSDASCKSRYSTKSCMSRRSRAKSCGYRSDCKESGKSGLRMRRKRRASMLLKSSADDTVEDQDILQLAGLSLGQSSEESNEYISKPSLKSLPTTSASKKYGEINRYVTTGQYFGRGGSLSATNPDNFISKMMNQRKETPAPSKSSCKIKSRRSSAASMCSSYVSGVSRMRRRHRRKSFSHNKSLNIDSKLLTEIEIITSTFNSRCRIQDDRLTGSSGKEKLLADANKLQATLAAPSPAQQLTLNGGGPASTLSKPLKRGLKKRKLSEPLVDFAMLSASASGTPNGSGSSNGNTKRRHKKSQSNDSSSPDDHKLPLKKRHYLLTPGERPPAEVAFANGKLNAEAWAAAAAAAKSTASTKSQAQFNARSVKSALTPKKRHLLEQPTSVSGAGSSASNSPLRIVVDNNSISGGKLLDISPSSLCSLKQQRRGGAAKQKVSAAKDLVQLQSPAGSYPPPGVFEPSVELEIQIPLSKLNESVITKAEVESPLLSALDIKEDTKKEVGQRVVETLLHKTGGNLLLKRKRKKINRTGFPTVRRKKRKVSVEQQTTAVIDEHEPEFDPDDEPLQSLRETRSSNNVNVQAAPNPPLDCERVPQAGEARETFVARTNQKAPRLSVVALERLQRPQTPARGRPRGRKPKNREQAEAAPQPPPKSEPEIRPAKKRGRQPKQPVLEEPPPTPPPQQKKNKMEPNIRLPDGIDPNTNFSCKIRLKRRKNLEAGTQPKKEKPVQPVTVEEIPPEIPVSQEEIDAEAEAKRLDSIPTEHDPLPASESHNPGPQDYASCSESSEDKASTTSLRKLSKVKKTYLVAGLFSNHYKQSLMPPPAKVNKKPGLEEQVGPASLLPPPPYCEKYLRRTEMDFELPYDIWWAYTNSKLPTRNVVPSWNYRKIRTNVYAESVRPNLAGFDHPTCNCKNQGEKSCLDNCLNRMVYTECSPSNCPAGEKCRNQKIQRHAVAPGVERFMTADKGWGVRTKLPIAKGTYILEYVGEVVTEKEFKQRMASIYLNDTHHYCLHLDGGLVIDGQRMGSDCRFVNHSCEPNCEMQKWSVNGLSRMVLFAKRAIEEGEELTYDYNFSLFNPSEGQPCRCNTPQCRGVIGGKSQRVKPLPAVEAKPSGEGLSGRNGRQRKQKAKKHAQRQAGKDISSAVAVAKLQPLSEKEKKLVRQFNTFLVRNFEKIRRCKAKRASDAAATASSPALGTTNGDIPGRRPSTPSSPSLAAQISALCSPRNIKTRGLTQAVHDPELEKMAKMAVVLRDICSAMETLKMSDLLTTVSSKKKKPIKTTLSGKLGSTAATSKVEFRSIQAQVEQGHYKTPQEFDDHMQQLFVEAKQQHGDDEGKEKALQSLKDSYEQQKIASYVQLVEILGDSESLQSFKPKEVLSSEEEPGKIAVKKSPGAKERDSPIVPLKVTPPPLLPIEASPDEDVIRCICGLYKDEGLMIQCSKCMVWQHTECTKADIDADNYQCERCEPREVDREIPLEEFTEEGHRYYLSLMRGDLQVRQGDAVYVLRDIPIKDESGKVLPTKKHTYETIGAIDYQECDIFRVEHLWKNELGKRFIFGHHFLRPHETFHEPSRRFYPNEVVRVSLYEVVPIELVIGRCWVLDRTTFCKGRPMECNDEDHCYICELRVDKTARFFSKAKANHPACTKSYAFRKFPEKIKISKSYAPHDVDPSLLKTRKQKTELDVGAGPTTMHKVSGRQEQHQAKMVGRKPRGISAPADATAVHVVTPVAPNKQMLKKRKSRLENVLITMKLKCLDAQTAQEQPIDLSYLLSGRGARQRKTQQSSSSSTANST
The following text describes a protein:
Function:
Represses or inhibits nitriles production from methionine-derived and from indol-3-ylmethyl glucosinolates. Favors isothiocyanate production.
Miscellaneous:
MISCELLANEOUS: ESM1 is highly expressed in cv. Columbia while lowly expressed in cv. Landsberg erecta.
Subcellular Localization:
Secreted.
Sequence:
MADNLNLVSVLGVLLVLTIFHNPIIVYAGEGVPNVALFTFGDSYYDAGNKVFLSQRKDLPQTYWPYGKSRDYPNGKFSDGHIVPDFIADFISIPNGVLPPVLKPGVDISRGVSFAVADASILGAPVESMTLNQQVVKFKNMKSNWNDSYIEKSLFMIYIGTEDYLNFTKANPNADASAQQAFVTNVINRLKNDIKLLYSLGASKFVVQLLAPLGCLPIVRQEYKTGNECYELLNDLAKQHNGKIGPMLNEFAKISTSPYGFQFTVFDFYNAVLRRIATGRSLNYRFFVTNTSCCGVGTHNAYGCGKGNVHSKLCEYQRSYFFFDGRHNTEKAQEEMAHLLYGADPDVVQPMTVRELIVYPTGETMREYWEPNNLAIRRRPSRDFYLGLAAYY
The following text describes a protein:
Function:
Binds to tRNA and functions as a cofactor for the methionyl-tRNA synthetase (MetRS) and glutamyl-tRNA synthetase (GluRS). Forms a complex with MetRS and GluRS and increases their affinity for cognate tRNAs due to the presence of a tRNA binding domain in its middle and C-terminal part (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MSFLWAKEFCVLKYPYKLFITHKFSYLLRFETVTLNNIRSPQFYAKLTFSHHQPTVSGTMSTELKFISKYLQISIPETKEGPVSSLFKAVSEQKPELLGNTDFEKAQILEWTTKAFSPIETQSIVEQLDEFLKSSTFIAQDSGISVADLAVYARIHSYICGLSAKEGYKLNNVCRWFDFIQHQESVMEAANSMSMKLANIDLNAPKIQRPSVIKKDKKEKKEGKPSQEASVKSVEKAPKGLEGAKKEKQNKKEKKDKKDKKDKKEKAPKEPPKAATPVPSMIDFRIGFIEKAVKHPNADSLYVSTIHCGDAEGPRTVCSGLVKYIPLEQMQQRKVIVVANLKPVNMRSVKSQAMVFCASSPDKSVVEFVLPPENAEIGDRLTFEGFDTEEPEAQLNPKRKIWEAIQPGFTSGEDLICGYKDESGLHRLFVKGKKDLGFCKAQTVVNGTLS
The following text describes a protein:
Function:
Contributes to degradation of small RNA (sRNA) RhyB. Upon overexpression suppresses sRNA-mediated RhyB-silencing of multiple RNA targets but not other sRNA's targets; overexpression leads to loss of RhyB sRNA. Enables degradation of RhyB by 3' to 5' exoribonuclease PNPase (pnp). Endonucleolytically cleaves ssRNA, probably generating a 3'-OH and a 5'-phosphate group.
Sequence:
MIRSMTAYARREIKGEWGSATWEMRSVNQRYLETYFRLPEQFRSLEPVVRERIRSRLTRGKVECTLRYEPDVSAQGELILNEKLAKQLVTAANWVKMQSDEGEINPVDILRWPGVMAAQEQDLDAIAAEILAALDGTLDDFIVARETEGQALKALIEQRLEGVTAEVVKVRSHMPEILQWQRERLVAKLEDAQVQLENNRLEQELVLLAQRIDVAEELDRLEAHVKETYNILKKKEAVGRRLDFMMQEFNRESNTLASKSINAEVTNSAIELKVLIEQMREQIQNIE