lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
Sequence:
MTSISEFASTAETMVSRIGSIGSSKVYLLDDHAKTLPLAQAIATANISKGSDDAFTILNLDALYKRFKLWKRELPQIELFYAMKCNSDETIIRSLAALDVGFDCASKEEIDMVIRIGVSPDRIIYANPCKSSKFIEHADLKGVKTMTFDSVDELEKIAEHHKCPGLLLRFNVSDPTATHPPSGKYGADPENTAPLLLQRAVELGINIGGVSFHVGSGCNDPSVYRTAIQHSRNLVNIGRDLGHTMAIVDVGGGFPGAEQRMPHFEKIASVIRSSLDEFFPEKDVRLIAEPGRYFAAPLCTLVTNVIAVKTVLGANGSAGKIHYFINDGIYGSFNCRIFDHARPVGRPLFDAGGEEYLSTFWGPTCDSDDRVEDNKMMRLLNAGNWVVYEEMGAYTSAASFTFNGFPRPTAIHLYCYHYETSVIPRTYSTNRAHNEECDQPMSLMEANFLKETALSSAISAFFRPAHTRGNNSSNPYWNDRGVSDNNNNDKNTNKYT
The following text describes a protein:
Function:
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MPATAYERVVYKSPSEYHYMKVCLEFQEHGVGLNVAQFKQLLVSALRDLFGEVGAALPVDVLTYDEKTLSAILRICSSGLVKLWSSLTLFGAYKSKKCAFRVIQVSPFLLALSGNSREQVLD
The following text describes a protein:
Function:
Mediates the export of free fatty acid from the plastids. Potentially prefers palmitic acid (C16:0) over oleic acid (C18:1) and stearic acid (C18:0). Not involved in fatty acid activation. Required for biogenesis of the outer pollen cell wall, in particular for the assembly of exine and pollen coat and for the release of ketone wax components.
Miscellaneous:
MISCELLANEOUS: For all TMEM14 proteins, 4 hydrophobic alpha-helical domains are predicted. However, NMR structure determination of the human TMEM14A showed that only 3 of these helices are membrane-spaning while the amphiphilic N-terminal helix is probably located at the lipid micelle-water interface.
Subcellular Localization:
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Sequence:
MASQISQLACFSSTNRQFHFQSRSFPCPMIRPQSFVVKSVDGNSSETPASLSYTAEVSKPVVEKTSKPYSTVDETATNKESITEPVEEDVATQPIRAAKIHDFCFGIPYGGLVVSGGLLGFAFSRNLTSLSTGVLYGGGLLALSTLSLKIWREGKSSFPYILGQAVLSAVVFWKNFTAYSMTKKLFPAGVFAVISACMLCFYSYVVLSGGNPPPKKLKPSATSPSY
The following text describes a protein:
Function:
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSLCGPLNLSLAGEATPCAEPGAPNASAWPPSGRASASPALPIFSMTLGAVSNVLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYAAGRSPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSAARARLALAVLAALALAVALLPLARVGRYELQYPGTWCFIGLRPAGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRRPQACGPDGRRHWGARAPRSASASSSSSVASVPGGSPGRGSARRARAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAVGGWGSSSLQRPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRPGAKGSPAGLALTRSAWEASSLRSSRHSSLSHL
The following text describes a protein:
Function:
Acts almost equally well on phenylacetaldehyde, 4-hydroxyphenylacetaldehyde and 3,4-dihydroxyphenylacetaldehyde.
Miscellaneous:
MISCELLANEOUS: Can also use NADP, but prefers NAD.
Sequence:
MTEPHVAVLSQVQQFLDRQHGLYIDGRPGPAQSEKRLAIFDPATGQEIASTADANEADVDNAVMSAWRAFVSRRWAGRLPAERERILLRFADLVEQHSEELAQLETLEQGKSIAISRAFEVGCTLNWMRYTAGLTTKIAGKTLDLSIPLPQGARYQAWTRKEPVGVVAGIVPWNFPLMIGMWKVMPALAAGCSIVIKPSETTPLTMLRVAELASEAGIPDGVFNVVTGSGAVCGAALTSHPHVAKISFTGSTATGKGIARTAADHLTRVTLELGGKNPAIVLKDADPQWVIEGLMTGSFLNQGQVCAASSRIYIEAPLFDTLVSGFEQAVKSLQVGPGMSPVAQINPLVSRAHCDKVCSFLDDAQAQQAELIRGSNGPAGEGYYVAPTLVVNPDAKLRLTREEVFGPVVNLVRVADGEEALQLANDTEYGLTASVWTQNLSQALEYSDRLQAGTVWVNSHTLIDANLPFGGMKQSGTGRDFGPDWLDGWCETKSVCVRY
The following text describes a protein:
Function:
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (Probable). Uses NADPH as a reductant with much more efficiency than NADH.
Subcellular Localization:
Cytoplasm.
Sequence:
MKYGIVGYSGRMGQEIQKVFSEKGHELVLKVDVNGVEELDSPDVVIDFSSPEALPKTVDLCKKYRAGLVLGTTALKEEHLQMLRELSKEVPVVQAYNFSIGINVLKRFLSELVKVLEDWDVEIVETHHRFKKDAPSGTAILLESALGKSVPIHSLRVGGVPGDHVVVFGNIGETIEIKHRAISRTVFAIGALKAAEFLVGKDPGMYSFEEVIFGGE
The following text describes a protein:
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins.
Sequence:
MILCLHFAGKSKIGFRGPKLTMNLFEELDTLDPSFKLEPPRIETPTAHKITVLILLKQYVINKKNCLDTGISMRTQRRRMFYMLVFKLIQEQDKSYNELHSLLTTGKYKLDTLMLESFEKAMSEFCAGSIEALFDFSEIQNIDEILNENYGISQFSMVGVYVRRVGVVLERLSFPEMMDMYKNVCSYYERGVRAAASGSRMAVAGGILHREETPPPNPITEKPEDPKPKKKVEAVARIAQERNPMSKWAPKQAKFFINKQSELLENNERKALPPLELQKKVQEIIHDLPLTTTPYFLGYMNRLRVRDYYNALSALHRALDRSPVRLMSQEKGYQYFCVNLAVLHATFGHRDEALAALRESIMLAQEHGDKRSLNLANTWYCLLRDELPLSAVQKSVQDANEVDGSLLQNYTLALHFAVKLGTVAGYQPLRLFDLLQHSDNLTNRNNFADHASEALALRSAVWSAYGRHELAALYSQVLLTGRDRFGSGSAGLGSALASFALWLQLQGEPQLSKVLLHHAKQRFPRLPSAEGWMISQCHVVIQAGIYQCRWHDALKACDQLYLIDPSDSLFQRASIYVAKREFFNARRLLDKLAVQDNIPFLLRMRVQVLLGYCGMANGRFSSETTMLLLRVSEEMSEAQMDYELALVDLLLAQQLLLLGMPQKAYQAIKRCMHDIHINGGLYERAKTDFVFVRCLLAVNQNDAEKRKAQLLKSQVILQRAAQSFKKLSAHAKVLDVTCSWHSDLTNLAIGI
The following text describes a protein:
Function:
Acts as a regulatory protein involved in the regulation of numerous cellular processes. Together with its homolog TMC6/EVER1, forms a complex with calcium-binding protein CIB1 in lymphocytes and keratynocytes where TMC6 and TMC8 stabilize CIB1 levels and reciprocally. Together with TMC6, also forms a complex with and activates zinc transporter ZNT1 at the ER membrane of keratynocytes, thereby facilitating zinc uptake into the ER. Also inhibits receptor-mediated calcium release from ER stores and calcium activated and volume regulated chloride channels. Down-regulates the activity of transcription factors induced by zinc and cytokines. Also sequesters TRADD which impairs the recruitment of TRAF2 and RIPK1 in the pro-survival complex I and promotes proapoptotic complex II formation, and may therefore be involved in TNF-induced cell death/survival decisions.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Note=Localizes to the ER, Golgi and nucleus membranes in keratinocytes.
Domain:
The TMC domain mediates the interaction with SLC30A1/ZNT1.
Sequence:
MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQTLRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTNTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLLGLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASARRFRFPSGAEL
The following text describes a protein:
Function:
GTPase-activating protein (GAP) for ARF1 and ARF2. Involved in intracellular vesicular transport. Required for transport from the trans-Golgi network. Implicated in the regulation of retrograde transport from the Golgi to the ER and in actin cytoskeletal organization. May be involved in the maintenance of mitochondrial morphology, possibly through organizing the actin cytoskeleton in Saccharomyces.
Miscellaneous:
MISCELLANEOUS: Present with 9560 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Mitochondrion. Cytoplasm, perinuclear region. Golgi apparatus. Note=Found also in the mitochondria and in the perinuclear region.
Sequence:
MSDWKVDPDTRRRLLQLQKIGANKKCMDCGAPNPQWATPKFGAFICLECAGIHRGLGVHISFVRSITMDQFKPEELLRMEKGGNEPLTEWFKSHNIDLSLPQKVKYDNPVAEDYKEKLTCLCEDRVFEEREHLDFDASKLSATSQTAASATPGVAQSREGTPLENRRSATPANSSNGANFQKEKNEAYFAELGKKNQSRPDHLPPSQGGKYQGFGSTPAKPPQERSAGSSNTLSLENFQADPLGTLSRGWGLFSSAVTKSFEDVNETVIKPHVQQWQSGELSEETKRAAAQFGQKFQETSSYGFQAFSNFTKNFNGNAEDSSTAGNTTHTEYQKIDNNDKKNEQDEDKWDDF
The following text describes a protein:
Function:
Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5.
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Membrane; Single-pass type I membrane protein.
Sequence:
MEIGAGPHPLRLLVCLMPLCLALLLGPGRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADLGRGRTRTGSSRPRKIDTIAADQSFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVTGTCVAHSEGEPGPPRMHCGADGEWLVPVGRCSCSAGFQERGDICEACPPGFYKVSPRRPLCSPCPEHSRTLENASTFCVCQDNYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLALRLRWLPPADSGGRSDITYSLLCLRCGREGPAGACEPCGPRVAFVPRQAGLRERAATLLHLRPGARYTVRVAAVNGVSGPAAAAGATYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPITAGAPGANGTEYEIRYYEKGQSEQTYSTVKTGAPAVTVTNLKPATRYVFQIRAASPGPSWETQSFNPSIEVQTPGEAATGSREQSTAVVITVVTISALLVLGSVMSVLAIWRRPCSYGKGGRDAHDEEELYFHFKVPTRRTFVDPQSCGDPLQAVHLFAKELDANSVTLEKSLGTGRFGELCCGCLQLPGRQELPVAVHTLREGCSDSQRLSFLAEALTLGQFDHSHVVRLEGVVTRGSTLMIVTEFMSHGALDSFLRRHEGQLVAGQLLGLLPGLASAMKYLSEMGYVHRGLAARRVLVSSGLICKISGFGRGPRDRAEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGVLMWEVMAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPSPLHRLMLDCWQKDPGERPRFSQIHGILSKMMQDPEPPKCADTTCPRPPTPLEDRAFSTFPSFGSVGAWLEALDLGRYKDSFAAAGYGSLEAVAAMTAQDLVSLGISSAEHREDLLSGISALRARVLQLQGRGVQV
The following text describes a protein:
Function:
Acts as a positive regulator of ciliary hedgehog signaling. Required for centriole stability (By similarity). May play a role in counteracting perturbation of actin filaments, such as after treatment with the actin depolymerizing microbial metabolite Chivosazole F.
Subcellular Localization:
Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Sequence:
MGRRRQRVDPAAGARAGALPEAIAALSRSLPSGPSPEIFRRAKFDRPEATSALWQLLFRVLSPLPAGNALASLALEVQARLVKSALCSQGYPRLALAQLPEDGSQGSRELLLALSWLLARGPVPEQMLAQARVPLGDEMTVCQCEALASPGPPAPHMEAEGPVDVRHVQWLMGKLRFRWRQLVSSQQEQCALLSKIHLYTRGCHSDQSLSHLSVTEAEMLRDPEGGQQVSGAGAAQNLDLAYPKCLHSFCTPGMGPRTFWNDLWLVCEQPGLLPGDWAAPLDPGGASACSLLSPFRALLRTLERENQRLEAVLAWRRSELVFWRWMDTVLGTCAPEVPAAASQPTFLPWVPERGGGELDLVVRELQALEEELREAAERRRAAWEAKAGGCGRGPEWSAARRASREAVEKELGALQQCWERDGGPAQPHGPHRLVRREDGAAGDRDLRAAVVIRTLRSQEACLEAVLRRLQGQCRQELARLVGARPGLIWIPPPGR
The following text describes a protein:
Function:
H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSRKASEDVEYTLRSLSSLMGERRRRQPEPGAPGGERSLLAAESAASLQGAELERAARRQFQRDETPAFVYAAAAFSALGGFLFGYDTGVVSGAMLLLRRQMRLGAMWQELLVSGAVGAAAVAALAGGALNGALGRRSAILLASALCTVGSAVLAAAANKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAIPAVIQFLGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIRNSIEEEEKEASAAGPIICRMLSYPPTRRALAVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASITAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALTILALGFLLSAQVSPRVTFRPTAPSGQNATCTEYSYCNECMLDPDCGFCYKINSSAVIDSSCVPVNKASTNEAAWGRCENETKFKAEDVHWAYSFCPTPYSWTALVGLVLYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFVYGCLPETKGKKLEEIESLFDHRLCTCGTADSDEGRYIEYIRVKGSNYHLSDNDASDVE
The following text describes a protein:
Function:
Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MKKPNNATAGSSKTKFKEESEEDNKTTSVTSSEEEEEIERELAEITFEDLLKARSDGSHLVYRKNSQEKKAGRANKNRPMEVSAKKPVSRFREVVQAPKRVVRDPRFESLCGNLDVEGFRKRYDFLFENTLPAEKEELKKQLKKTNDPNAVDKLKKRISWIDKQLRFESTKSTDAAILAEHKKKEREAAKHGKRPFYLKNCNRKSASKDSLRNITSSRGLAKLNHSLRKDEGRMLQRITNTCHIVGPIIMTNRTNDFTCFWLRNELYMPHRPIVHMVVRTSPCLVPNIL
The following text describes a protein:
Function:
Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB). Also required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH (By similarity).
Subcellular Localization:
Cytoplasm. Endosome membrane; Peripheral membrane protein.
Sequence:
MWSYLFGSGNAKQKKELPKKAILELREHIQLLSKKQAHLQTQMTSQEESARHFLSKGNKNMAKAALKRKKVFESQLLKIDKQVDSLEQQLYSIENANLNLETMKAMKQGASAMKHIHEGLDVERVDETMDEIREQVELGEEISEAISRPLYTGVNEIDEDELDEELDMLAQEEVARKVMEPGAAVPAAAPATKVSLPSVPSSDMPQQDRGQPVTLGMDQEEDEDERALRELQAEMGL
The following text describes a protein:
Function:
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
Sequence:
MGNVNQKPQPNSQTLQQIEEEESASSTFTCEICIEPVTLPNKRFKNSNRCVHPFCTDCMIKYIQVKLEDNVSDIKCPALTCDHSLEPLSCRPKIAHQLFDKWCDVLCESAVLGLDRVYCPNRDCSALVINECGGEGNLKRCVCPNCKKAFCFRCKVPWHAGYRCEESGEMRDRNDIAFGVLSERNQWMRCPMCRHCVELVKGCAIVKCRCGIEFCYKCGKKVDHHWCNCRRSSTFCMWIFHLCIVILVLWPFFLLFTAITRKGHH
The following text describes a protein:
Function:
Part of an ABC transporter complex involved in ferric-petrobactin uptake. Probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSKNMISRVENISQPQFYNQNKIWTKPFIIAVIVVIILGIISLFTGVYDIRGQEDGTEMFFITRVPRTAALMLTGAAMAMAGLVMQLITQNRFVEPTTTGTIEWSGLGLLFVYLLFPAPTLVQRMTGAIIFSFIGTMIFFLFLRRVKLRSSLIVPIIGLMLGAVISAVSTFLGLLFQKTQSIETWFVGSFANIQVGRYEYLWLIVIITFLIFMYANRLTLAGLGEDVATSLGVNYNRIVLFGTALISVAVGIVAAVIGHLPFLGLIVPNIVSMFRGDDLRSNLPWVCVIGMGSITACDIISRTIIQPFELPVSLILATVGAVVFITILLSQRKPRRLR
The following text describes a protein:
Function:
Transposase-like protein that is essential for plant growth and development. May regulate global gene expression by recruiting other cellular factors.
Subcellular Localization:
Nucleus.
Sequence:
MDEMIPKPLISNDNEMMHGHGYTTMVHGNNEILNGNELAVHAEVIPSASTRGQKRKSAIWEHFTLVDVSDGCKRASCIHCNQSLAYSSGSKNSGTSHLTRHIAEWCRVLKDRQKSRRYTTYNSSNENASFDQERSCLRLAKMIILNDYPLHIVQQPAFLSFVDSVQPNFKMVDIGTIETEVYAIYLKEKDHLQQALANIPGRISLTVGSLTTNQSIRYISLAAQFIDSEWRLHRRVLKVMMAPWPQSENAVSRAIIKCLSDWNMQDKLFTITLEHDCSSHDIYSANLRNHLSGDNILMLKGQTFAVRCYANILNAVAHGVLASVHNVIYLIRESIKFIKADDAHENKFAEIAVELKITSNNSLCLDVTSEWNTTYLMLLAALDYRQVFTLLESYYDNYGTAPSTEDWKKVEAACGFLKLLYAFTLNIMSAEGNHQTANMFFHDAWVLQLELQNGMAHGDDVIRGIVIGIHEKFDKYWKDCNVVLAIAVAMDPRFKMKMVEFAYSKIYGPTDAAKYVKLVDDAILDLYKEYAAQPELLPLSPIYVDQVPADGLPFIETGGAPATASPSTAAAGAGLVDFDMYLSEVTTMGQPFKHELELYLEEALTQRTPDFDVLKWWQDNTLKYPTLSRMARDVLAIPMSTVGVGSSVFLPDNGSRSLDDYRSSLRPELVEALLCAKDWLQYSP
The following text describes a protein:
Function:
Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
Subcellular Localization:
Mitochondrion.
Sequence:
MLRRAVPRFFSRTRPALVNLHASELSTPDRSTVNSTNRKELKTPLCVELISKMSSQGYFPMSQFVKECLTHPQHGYYSTKKNVIGSEKADFITAAEIPFFADIVSAWIMDVWQKMGTPRVLHLVELGPGRGTLMKNILKQIKYSNPHLLHFLQIHLVEVGAARTDEQRSALSEFQTAQKKIKWWMGLESIPLTLEPTVYIANEYFDALPVAQFRYTERGWVETCLEVDEDPAHEAHFRMVHAPSGSFSAYLIPNDVRANGKIGDCIEINAVGMQTMELIMKKMVECQKSACLIVDYGKDEHMHSTLRGIRGHRFVDPLLSPGEVDLSSWVSFKQLRWSMERLETARRHLKWFPVISQSEFLQWGGIDVRLAHVIKDEETKSAMKILQNYRRLMDKNEMGESYKVFALQTRNFPNVSPFFQEAELPSSL
The following text describes a protein:
Function:
May be involved in sperm-egg fusion.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MSVAASASRSASTLCSPQIQQGALKEAKVPPHIWAARHWNLGLRLVPGHASVRAGILVLLIFLPSTLCDLGSVYDSSYETVIPERLPGQGSDDPGGKVSYVLLMQGQKQLLHLEVKGHYSERNFPVYSYHHGILGQEVPLLSQACHYEGHIEGVPGSFVSVSICSGLRGVLIKEETAYGIEPLLFSTDFEHILYTMAHQPVVLCNVTPTDSLGDSSQRQGSSKTDELLALSDLWSHAKYVEMFVVVNHQRFQMWGSDVNTTVQAVVDIIALANSFTRGINTEVVLVGLEIWTEGDPIEVPVDLQATLRNFNLWRQEKLMGRVRHDVAHLIVGHRPGANEGQAFLDGACSGGFAAAVEAFHHEDVLLFAALMAHELGHNLGIRHDRPGCTCGPKHLCLMHETISKTSGFSNCSSDHFLRFLHDHRGACLLDRPWHQSHKRRDAHCGNGVVEESEECDCGNACDSHPCCEPTCTLKVGAQCSEGLCCYKCTFKKKGTLCRPAEDVCDLPEYCNGITGECPANSYMQDGTQCDRIYYCSGGLCKNPDKQCARIYGYPARSAPEECYISVNTKANRFGNCGHPTSANLKYEACSNEDIFCGKLVCTDVRYLPQVKPLHSLLQIPYGDDWCWSMDAYNVTDIPDYGDVQGGTYCAPKKVCMESICTGHATLQYDCHPQEMCHGNGVCNNFKHCHCDAGFSPPDCSSGGNGGSVDSGPVGKPADRNLSLFGVGESPDSRMEDEEINLKVVVLVVPIFLIVLLCCLMLIAYLWSEVQEAVSPGSSSTTSSSESESD
The following text describes a protein:
Function:
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression.
Sequence:
MDELDIMERNKKKLTLPLSNDCVFSPCFSQTQASPVTALSMSMVTLSCMGGTPKRRLSMSSIGEASPVPPNLSRHSSHSSGVSVGTPSPCESPLILGTFQPINPSNDQPESSRHSTQFRRFNSMPLRLQQQHQESPSLQMFHRPRLIRQHGLEEPMKEEEKEDGLWMMKPAGKRKDSEEEKEEEKADSMQLDLPSPDIVEEATLPSEGFTFVMPKPLSARPASSRVSSLNFAPAGSRPISAPATLLDEEDDDDAIQLQEDRLTSFHDDEDDDADNDDGFSDIFDTDSQEGSSSAFSDGLAGLIHGALISPAGKAINSPPSHSIASESSQSGNIPNRGVDCNTLRTTPSGGPRCRKGIFKIPSQPVLARRNSSFLKRTERPQDTPSPVQNKRPRSSSVASPQVTSMEAEKTSPKNRMCLGRSLSMLSPNDPYFRRIDQALSIEGGQHNLTGDRTKACSVPLVTGKQKDLKCISPETMCRLLRSEYDQEIAECHVIDCRYPYEFNGGHIKGAINIYEEVELKKMFLENPLPPLPNNGRRVYIFHCEFSSQRGPKMLRLLRAQDRAANLENYPALYYPELYLLNEGYKAFFEYSTEFCEPKIYTPMNHDDHLEDLRYFRAKSKSWTERSRLVTRSKSLF
The following text describes a protein:
Function:
Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Sequence:
MLNYILNYDNENIEEDEEDEYEEDEYEEDENDEDQDEDNEEEEEEEDGDEEDGDEDDDIMENNNYQAKRTTVKLNVDEDSSDDESSNSKEHYYLFEALLKKNNINLYPIEDEKFDAQPYLTFLNSMTLSYPTLTFSQPLFNFIFEKLNNRDTESIIKETSIHKFPFCQFEWTKKTWFFRCKDCAQTETSCICISCMENSIHIKEGHAFMIEESGLGGCCDCGNPDSFKPSGFCTKHRDQNSPEHPSDKLNETTKKNFHITIRILVVHLLRTLDSLRFDNPKDTFSSFNGLELLFADFIRDEILKKKKRLDALDFQNRRTRVQHHRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEQIPQILQQQQQQFVFPGIDLQEIAELRQINFIDRVLDMGNNNLVGNVLQGQQQMQHPLQQLPQEQPQLQPPQEQQQQQQQQQQQQQQLPQQQQPPQEQPQEQQQQQPEEGNLGFGNLLVDNNIIQYFHRFINNINNEAIINNGLGPRFINNNNNNNNNNNNNNNNNNNNNNINNNNNNNNNNNNNNNNNNNNNNNNDNDNDNIGRYINFFDNQNRNNHYNEEEEEEDVNYSSDYSNTNKENSDSEMIQDSSLEEMDEDAGNNVDLRNLMYDSDSDSDSDSDSDSDEHIDRFNALRGLINNNGFNQIMRDFHNNIQQQQQNNNNNPNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNDNSDEEMIQNEEADESDCGDETELFNEVFSKNFHIFNDITKPISSNTKLNMDTPIFKKNIKKFTKKLVLSQSFNLFKFIDRLARKSYPLLYIISEEFSQRILDPNSFDLYSPVKLPYSEVLSYENVDQLKRENNAVGSIISLIHGEPRVLMIFRPLIITIIGNRYFKFIFCEEFLTNYPKLALSSNSQVRSLVSAISCQMFELPSIAVPFSTGYSKQNLLSILIKTKLSLVQTKNKYDLYNATQRKNYDQEFYCNQDYNYISNIFRHDKNCEYIDNNSDTVVNSLLAITDEIQLLCPIKRETQKAIEYELPVISNVVSIECQSFMAFDTFFHSLHKQGFSSLKYLDILLSHLQLSIDRHQNPDTALHRMFSGTLLPKANILSGEVAVPLHLPTNRLIGIYLLNSVYDSPQYSFDTIKSKIPLETVLFLATKSMLPAILVGQHQCRLWERNLNISDFTSYYIWSLFSIDLTLVQYCSMLLGTRHFILLALNNFSGNYNMDTDNPTMLSQFLKYIIVIIQHRKQAKYGIQEARYHIIQALTFNTNNFSKLLDQRKEFTLFNVEDIIKQVSHQPKPDGKLILKPEYWDRFDVYYPYHYFDPNSFTYKSLANYYDYLKQNNHPIPESYPLPSKTDPLPENLKNVEKLLNEPILFTILNSILLKFLYPNYNLISNSNNNVQNNDERDMDFYISNFLSLMLSAGKIKVDSNDFNQYYDPLLNHTLYIIVLSVRTFLESSISLTDQQLKQQFSKLINMSIANEKIEKSLFNDNIKSADGDNPMLLLFKPIEIIKNIEENEEKLDFNIKENNNNNQNNNHNNNQNIAETNLLNLIIELSLNIEKNNVFSDKKNLINKLFTMLYEYDNNIEKLLKEKKLDMASLLSQQSEIDANIRKKIAQERQEEIKRKMRMQQLQFLQSNELLNDDDDEDFNGSSTTTNEHIHSGEEKDLVCVVCKNNSNNITDPICSIGLIEHSSIKKFTNYQAFLRSSKPEQQQQQQQQQQQQQHNGEEVIEENKKHVDLPMNIETYEEYNKYDIDDLDIDLNIELMQFSNKTRVQTCGHYIHRSCLSVYAPYYVNDHFKCPLCNRASNIALIVKPINHSDLVAHPENTALVSNLFFSFVNSDWSYQYPPKQLNPSNAIYFLKFILSNIEILEITSRKNYNYTNSGINNLDGLNGIGNNNNNNNNGYYIYSKSEFQRQLETLTLLYNNVMKLTDIQFNYKYFDFYSLDQQKRFHNIDPFIICAMSHFLNRDVNPYPYIYKSYIHLASDIISSRISNPVHENYSLSNEGEIETIETILTPFIRKAYLFHHYCYLLVNHKSTNPSNQDTINTFSGLSIESFSNVKELIKKLGLPSIVDLVNSDEFSKRGTINPPSTQNLISLHTLPSYLPRFIDLPNDHIEFLISNITKSCKRKCDLLPKGVCLFCSTIVCFNGDCCEDEFKDHVTFCSYQGLFLGVCSPEVSIGFDDGDRDSSLCIYYDKFNEPALKSKPNLHLNLDCLKNIYIQFLKGLINQRKNNQL
The following text describes a protein:
Function:
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. May act as a translocator that mediates translocation of SPI-2 T3SS effector proteins from intraphagosomal bacterial cells into the host cells. SseB is required for correct localization of SseC and SseD on the bacterial cell surface.
Subcellular Localization:
Secreted. Cell surface. Note=Secreted via type III secretion system 2 (SPI-2 T3SS). After secretion, localizes mainly on the surface of the bacterial cell.
Sequence:
MSSGNILWGSQNPIVFKNSFGVSNADTGSQDDLSQQNPFAEGYGVLLILLMVIQAIANNKFIEVQKNAERARNTQEKSNEMDEVIAKAAKGDAKTKEEVPEDVIKYMRDNGILIDGMTIDDYMAKYGDHGKLDKGGLQAIKAALDNDANRNTDLMSQGQITIQKMSQELNAVLTQLTGLISKWGEISSMIAQKTYS
The following text describes a protein:
Function:
Transcriptional activator involved in cell elongation. Regulates the expression of a subset of genes involved in cell expansion by binding to the G-box motif.
Miscellaneous:
MISCELLANEOUS: Plants over-expressing BHLH49 show increased hypocotyl and cotyledon lengths and increased flower size; MISCELLANEOUS: [Isoform 2]: May be due to a competing acceptor splice site.
Subcellular Localization:
Nucleus.
Sequence:
MDLSAKDEFSAEKRNPDNYDSVNNPSGDWRVDSYPSENLISAGPASCSPSQMMDSFGQTLWYDPTSVQAVGYAGFNGGNASSSSFRGSIDRSLEMGWNLPNLLPPKGNGLFLPNASSFLPPSMAQFPADSGFIERAARFSLFSGGNFSDMVNQPLGNSEAIGLFLQGGGTMQGQCQSNELNVGEPHNDVSVAVKESTVRSSEQAKPNVPGSGNVSEDTQSSGGNGQKGRETSSNTKKRKRNGQKNSEAAQSHRSQQSEEEPDNNGDEKRNDEQSPNSPGKKSNSGKQQGKQSSDPPKDGYIHVRARRGQATNSHSLAERVRREKISERMKFLQDLVPGCNKVTGKAVMLDEIINYVQSLQRQVEFLSMKLATVNPQMDFNLEGLLAKDALQLRAGSSSTTPFPPNMSMAYPPLPHGFMQQTLSSIGRTITSPLSPMNGGFKRQETNGWEGDLQNVIHINYGAGDVTPDPQAAATASLPAANMKVEP
The following text describes a protein:
Function:
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
Subcellular Localization:
Cytoplasm.
Sequence:
MEFGALREEMVDSLLDAGTALADARPADAAMRAVPRHEFVDAGHRAYTDQAFEHRGTRVLAPSTVARLVGALEPRAGDDVLVVGAGVGYTVAVVAEIAGPTHVHAVDIDRQVVYDARGNLADAGYEDVLVDCRDGAEGLAEYAPFDRVLVEAGAASVPDALARQLAADGRLVFPEGVGDQRLVSVRDGETVGVHGPVSFAPLLVAGEQASAVERNRTVREDRERVREAAQSRPGWEREWIDWEDA
The following text describes a protein:
Function:
Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
Sequence:
MSLPAGVQRRSFGDEDGVLATRGEPAYGEPVVDGWRRWDAHRSKLGATFELGLDTGLSGGDAVLYLGAANGTTVSHVADFAGPTYAVEFAPRPVTDLLAVADSRERLFPLLKDARAPETYAHVVESGVDAIVQDVATRGQADVALSNRQFLADDGRLVAALKARSEDVTADPAAVFEDLLGRLRDGYEVRATARMEPFHEDHLAVVATPR
The following text describes a protein:
Function:
Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MDFAELKHTLRSINIDVLYSVTERTFLSPFFACWIPLLALGQSAPGFYYWSLRFLWFVLFRTALCWSSQMWRNRRWRRGQIDWNDQVVLVTGGSEGLGRVLVETLLLKHISVIVLDIKPFSDRDEEEEGDLKFYQCDVSDPQAVEKAAIQIRKDVGSPTIIVNNAGIVHGKSLLELEPDELQKTFAVNVFAHFYLYKAFLPDMIKRNSGHIVTMASILGHVGVSRVADYCASKAAAILLHQSLREELHSVHHAHGIHTTLVCPGLMNTKMFENVKTWNEFMFPRLSPHELMKKIIQTIDNEDSTEIYMPLYTKFNFIFDLSEFFLVPSWFLSFLHWFVGSNRAYNPHLSDPAAAAVDPSVTHQKTR