lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Modulates cell-to-cell trafficking.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: May be due to a competing acceptor splice site.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Cell junction, plasmodesma. Note=Co-localizes with the Grapevine fanleaf virus (GFLV) 2B-MP at the base of tubules within modified plasmodesmata.
Sequence:
MVVHLISLLTQTLALIILSLPSIINTSQLDYDTLVFKQCDPLDANILQKATTKSPNYSNQNLFLRAQALSSFLRKLESESSRSKFLKTLVGNEKHAVSGWFQCREDYPSEICHKCVGDLREISSRSCGNATSARIHLRGCHLIYKFERIDTPGAQVNNHHKYKLFETPEHGLIHKICDGATAETFPGFEEMRTEALTAAETGVVDGHGFYEDSYKLLHVVAQCDGHVEACDCGECISSAAAAAAEECRWSIAGQIYLEGCHVGYTYHPHELPNDSYHEEGSKVNTGKSLAIVVGGVAALVFVAIFFMFLKSLRKKGDDC
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MCAKVSRKADAVLRRKAAATVRKPNPFETVVMKTKHAVLNRGTQSKRPGQLHRLSHEKREQTLGKEFALLHKTNQFMDARQNGRYARQPSRKEQAKEMYNLNLTHGGRTMHEIEHLDDVPDGADEDEDEDGMLQDAFTSATHFGGGSDDDSGRPAGKDRKTVIEEMIAESKRQKTERQRENDEMYEMRLRLDDELKSLMPQFTEHIRRDSERPKPDDYDRALREMVFEPRGAPTEKLKSIDRAAEEQKRREVAEREKQQRMQQQEAQRVTQGASRPISADALGDDYLVEGEGQEEAYYGEPDGDDVRNGSAPDEEEEEEEDEEEDDEGEESDSSEADSLSDLKAAVQQEDDSEDEQDAEPEPEPAKQTVAPKAKAKPAAVAPTYTLRMVDVPREYEQFAELLDGHEGDVQGRVGVVASMVHTLRQKPFLHKSRWSVLFAYALNYLGVRFAHATSATIAGEFEMLHLLTPLLHDIAQTDPSGIGRVFHSVLEEKYSVFRKQPRRYPDLATVVLLKLVPVLFSASDRRHSIVTPALVFVGEILSRCQVRNRRDIARGLLLVTTVLECAEHSKRFLPSTVAFLTGVLGQACAKDALHPLATVGQPFKLTSLQLSEADVLTEADAATTQLTGQDLLLGQLTPSFKVRAIVCTVTLLSALCTQLDSNPALPIVAAHFLIPLHAIRQAPSSQPVQTALDETIAQLSALAGRTLPYLAQAKQKPKPLRLLEPKINPVYEDIRRRPKTAVPVREQRRKLQQKIKKVTRGAKREIRLDNEYLAKLQHKRRMESDRERQQKVRQIFSHASHQQAELKSLDRRAKYRK
The following text describes a protein:
Function:
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MSAEIEDLLKRYQNYPNVSGIIILDPFAIPIKTTMEYTLTVHYAALISTLTYKAAKMITNLDASNELVTIRLRTKVHEVIVLPSENYIIIVVQNPGT
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MARVDFYRECDIVAEGVVPPQTGAIVSSDAYEASAKNVAEVLGQNQLLEGISVRTPGWLVNFFQKSRTVVTAGAERAAHQIETVSRRYYEKERRITSTVAALHSNPREELLPGFGAVAVAYFSGSVLTRKRGIVLRVCAPLALGLGAFSYFLPTTFRNTKSLCYDLEKRAFPQFVAQQDRLAAGTKRAVCGTVHTTVSAYNATHRACRKVTKVFRDWTGLNL
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSSLRNSVQRRSHKERAQPLERQRLGLLEKKKDYQKRAKDYKKKQEVLKSLRQKVAEKNEDEFYFGMMSRKGPGSAITYDGKKKNFTGTVEGDRGNKAMDVETVRLLKTQDLGYLRTMRNVAAKEVRELMERVILAGGADVDDDSEDDDDDFEDFNEDMGGSKNKKKSSSGRTAPKKIVFFDAAEERQQKLQAVEDQEMQDFDSEEDEEKAKEAGRKARNLARLQNRLKQAKKKLKALTDAETELEITQAKMAKTRTSGGITKSGRRIKVKERKR
The following text describes a protein:
Function:
Required for double fertilization of the egg cell and the central cell by two sperm cells, resulting in the formation of the embryo and the endosperm. Involved in the regulation of embryonic expression of PHE1. Essential in maternal tissues to ensure the paternal embryonic expression of several genes, including RPS5a and FAC1, both of which being essential for early embryo and endosperm development in fertilized seeds.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MGSSYQESPPLLLEDLKVTIKESTLIFPSEETSERKSMFLSNVDQILNFDVQTVHFFRPNKEFPPEMVSEKLRKALVKLMDAYEFLAGRLRVDPSSGRLDVDCNGAGAGFVTAASDYTLEELGDLVYPNPAFAQLVTSQLQSLPKDDQPLFVFQITSFKCGGFAMGISTNHTTFDGLSFKTFLENLASLLHEKPLSTPPCNDRTLLKARDPPSVAFPHHELVKFQDCETTTVFEATSEHLDFKIFKLSSEQIKKLKERASETSNGNVRVTGFNVVTALVWRCKALSVAAEEGEETNLERESTILYAVDIRGRLNPELPPSYTGNAVLTAYAKEKCKALLEEPFGRIVEMVGEGSKRITDEYARSAIDWGELYKGFPHGEVLVSSWWKLGFAEVEYPWGKPKYSCPVVYHRKDIVLLFPDIDGDSKGVYVLAALPSKEMSKFQHWFEDTLC
The following text describes a protein:
Function:
Catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides. In contrast to prosurvival SPHK1, has a positive effect on intracellular ceramide levels, inhibits cells growth and enhances apoptosis. In mitochondria, is important for cytochrome-c oxidase assembly and mitochondrial respiration. The SPP produced in mitochondria binds PHB2 and modulates the regulation via PHB2 of complex IV assembly and respiration. In nucleus, plays a role in epigenetic regulation of gene expression. Interacts with HDAC1 and HDAC2 and, through SPP production, inhibits their enzymatic activity, preventing the removal of acetyl groups from lysine residues with histones. Up-regulates acetylation of histone H3-K9, histone H4-K5 and histone H2B-K12. In nucleus, may have an inhibitory effect on DNA synthesis and cell cycle (By similarity). In mast cells, is the main regulator of SPP production which mediates calcium influx, NF-kappa-B activation, cytokine production, such as TNF and IL6, and degranulation of mast cells. In dopaminergic neurons, is involved in promoting mitochondrial functions regulating ATP and ROS levels. Also involved in the regulation of glucose and lipid metabolism.
Subcellular Localization:
Lysosome membrane. Cytoplasm. Cell membrane. Endoplasmic reticulum. Nucleus. Mitochondrion inner membrane. Note=In nucleus, is located in nucleosomes where it associates with core histone proteins such as histone 3. In apoptotic cells, colocalizes with CASP1 in cell membrane where is cleaved and released from cells in an active form.
Sequence:
MAPPPLLPVAASTPILHGEFGSYPANGPRFALTLTTQALHIQRLRPKPEARPRDGLVSLDEVSGCGTLQSRSPEDTAAYFCIYTYPRGRRGGRRRATRTFRADGATTYEENRAEAQRWATALTCLLRGVPLSGDQEITPELLPRKPRLLILVNPFGGRGLAWQRCMDHVVPMISEAGLSFNLIQTERQNHARELVQGLSLSEWEGIVTVSGDGLLYEVLNGLLDRPDWEDAVRMPIGVLPCGSGNALAGAVNHHGGFEQVVGVDLLLNCSLLLCRGGSHPLDLLSVTLASGSRCFSFLSVAWGFLSDVDIHSERFRALGSARFTLGAVLGLASLHTYRGRLSYLPATTEPALPIPGHSLPRAKSELVLAPAPAPAATHSPLHRSVSDLPLPLPQPALVSPGSPEPLPDLSLNGGGPELTGDWGGAGDAPLSPDPLLPSSPNALKTAQLSPIAEGPPEMPASSGFLPPTHSAPEASTWGPVDHLLPPLGSPLPQDWVTIEGEFVLMLGILPSHLCADLMAAPHARFDDGVVHLCWVRSGISRAALLRILLAMEHGNHFSLGCPHLGYAAARAFRLEPLTPRGLLTVDGELVEYGPIQAQVHPGLATLLTGPAGQKPQA
The following text describes a protein:
Function:
[ConoCAP-a]: In contrast to other members of the CCAP family which are cardio-accelerators, conoCAP-a decreases the heart frequency in Drosophila larvae (26%), rats and zebrafish embryos. It also reduces the blood pressure in rats. It decreases systolic calcium in ventricular cardiac myocytes, indicating that it may act via impairment of intracellular calcium trafficking; [ConoCAP-b]: Synthetic conoCAP-b decreases the heart frequency of 23% in Drosophila larvae; [ConoCAP-c]: Synthetic conoCAP-c decreases the heart frequency of 12% in Drosophila larvae.
Subcellular Localization:
Secreted.
Sequence:
MVSLGHVLFVILLPVLLPVAADDPDDQMLSQISLPSSSRSEYDDNDVSKRVFCNGFTGCGGRHRDRSRRQERYGKRLIPVLAKRPFCNSFGCYNGKRSLSGAGPALSTPVDPSRNNKARTMARMLDAAASARHEQQQQLLQQREQRGLESRDPAASGDLSKRLFCNGYGGCRGGKRTLYSPWLERMNEVADDRSARNALCTRLGWRE
The following text describes a protein:
Function:
Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia.
Subcellular Localization:
Cytoplasm.
Sequence:
MDEHNVHHFWGISPAVDLGTLLPTGDGAADLPVDQPVRFLQVAPYDARHTLTTLSRACRHPALMRQLPPGQPACRLYVWEDSPEGLARHVLLAAVLLDGGVPAAQRGQLLLELHGNAVLRRRAAEYLDEKARQLESLFVGLAAGQPPPAGPEAEARGLAALAALLDLSLLKFQEKDLIVEALQRWRLPNPTSSTSTSAASASAAAAPYDMVAAWDGRCRKVYGERYDFRRNMVDWDYHMRLQPAGTPGCDPASGSIIHFHHFRHWRLHGVAHELRDSAYNSANRCRGEGGVGEFKDRTGRDVGRSVSAWGFWADVLNSPYHAFGTACEQPEFYRITNKQFVRTAVDVAEHNIAALLHELRTGRRLELGEGQEAHRAQAARGPTTLEDLTAAAEEAAAAASGAGAEAGAGAGPGGEAAAGASSSSGKEEAAAAAAAGKEQGQGEGQGEDWTAGSGSGAPGAGTGQAVAEGREGPGGPQDSDPAAAASTAAPAAAAAAASSSSTSVPTYSSGGRAQVAKAMAAAAAAAGAGAGAGAEASSSGAASAASAAPTAGASSGAADGKAAEAAAAPLDEAAREQMAAEEAAVRAAEAALDAAARQRAGRFRLVLVTGDLAKTLTGRAKYAGAFSGLSLGHRHTHMLEPQYKLAAAAAPGARLVAENARHVLQLSQEQAALFAAKMDELAAAGGWRPLPAAQRPPGITEAAAVYVRAA
The following text describes a protein:
Function:
Involved in a glutamine-transport system GlnHPQ.
Subcellular Localization:
Periplasm.
Sequence:
MKSVLKVSLAALTLAFAVSSHAADKKLVVATDTAFVPFEFKQGDKYVGFDVDLWAAIAKELKLDYELKPMDFSGIIPALQTKNVDLALAGITITDERKKAIDFSDGYYKSGLLVMVKANNNDVKSVKDLDGKVVAVKSGTGSVDYAKANIKTKDLRQFPNIDNAYMELGTNRADAVLHDTPNILYFIKTAGNGQFKAVGDSLEAQQYGIAFPKGSDELRDKVNGALKTLRENGTYNEIYKKWFGTEPK
The following text describes a protein:
Function:
Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti (By similarity). Has a critical role in normal myelination in the central nervous system (By similarity).
Subcellular Localization:
[Isoform 1]: Cell membrane; Single-pass type I membrane protein; [Isoform 2]: Secreted; [Isoform 3]: Secreted.
Sequence:
MVAAAAATEARLRRRTAATAALAGRSGGPHWDWDVTRAGRPGLGAGLRLPRLLSPPLRPRLLLLLLLLSPPLLLLLLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICNSSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLKLPRASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVDTQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRWSVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDILVFTSEQCDAHRSEAACLAAGPGIRCVWNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDCHWCNDHCVPRNHSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQECIALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCRNHNALLASLTTQKKVEFVLKQLRIMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLRGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINASKNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNFTWPIKIQIAFSQHSNFMDLVQFFVTFFSCFLSLLLVAAVVWKIKQSCWASRRREQLLREMQQMASRPFASVNVALETDEEPPDLIGGSIKTVPKPIALEPCFGNKAAVLSVFVRLPRGLGGIPPPGQSGLAVASALVDISQQMPIVYKEKSGAVRNRKQQPPAQPGTCI
The following text describes a protein:
Function:
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Subcellular Localization:
Nucleus.
Sequence:
MVSVHSEAQGNRKSSTHAKHTVLLKGGSMESRLHVKSSQMKNPSQCKLTRVTLLSPLGKIQAAGCGNGVHYIQLQEDAVPAERNEMASFACVVCEGQEGMTAQLQLCTEWLQAYFCNPRTIEKLPLPALHHPIFQEVHCRIKRSGIWSLGPEGNLHAPTFTSRVLQTLLRDVKFGETVSYKHLAEMAGNSKAVRAVGGAMRRNPIPLLVPCHRVISCNGEIGNYMGGKGNHLKQWLLTHEKL
The following text describes a protein:
Function:
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
Sequence:
MNKNEKMVRSLMGTVVSNKMNDTVVVRVERRVKHPKYGKFIKRSTKIHAHDKGNEGQIGDIVTIRECRPISKTKSWTLVKINERAEKVE
The following text describes a protein:
Function:
Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
Sequence:
MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWAISGGGVEPGERIEEALRREIREELGEQLLLTEITPWTFSDDIRTKTYADGRKEEIYMIYLIFDCVSANREVKINEEFQDYAWVKPEDLVHYDLNVATRKTLRLKGLL
The following text describes a protein:
Function:
May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin.
Subcellular Localization:
Secreted.
Sequence:
MTFNVTAGWIRSSKEIPRSVEVSHCIPAPECGDTAAIKLKVSAGTEEQRSRGLTRATMEFGMLTLFALFSSLPGGLSLVPKGACLLRVDEGPCRGQIERYFYNTITQKCEVFYYGGCHGNANNFMSFQKCQKTCFRIPKVPQICRFPKEEGHCRALFPSYFFNMSTMQCEPFSYGGCGGNSNRFRDLTSCMDFCSPQKSVPILCLDPLDKGKCSASMRRFYYNKATKTCEEFAYSGCGGSSNNFVSRESCEDVCLKGAKKHTGLKGRDRLMKRNKKTRFMAFRG
The following text describes a protein:
Function:
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
Sequence:
MAALFIVLEGIDGSGKTTQGDLLLAHFQRQGLAAVLSPEPTNGPVGRLIRQALQGDLFTYNDARQFEAQMGYLFAADRHYHLYHPGDGVEAKLAQQCHVITTRYYFSSLAYNCHTEADWEFVQRLNQSFPQPDWVIYLDLPVDLALQRLGDRQQLEDQAPRECYEQREKLISVHRNYDRIFAHYQGQLCRLDASLPVEQLHQAIITKVEEML
The following text describes a protein:
Function:
Polymerizes D(-)-3-hydroxybutyryl-CoA to create polyhydroxybutyrate (PHB) which consists of thousands of hydroxybutyrate molecules linked end to end. This subunit has no catalytic activity but enhances the activity of PhaC, the catalytic subunit, 100-fold.
Miscellaneous:
MISCELLANEOUS: Poly(3-hydroxyalkanoic acids) (PHA), of which PHB is among the most common compounds, has potential uses as a renewable, biodegradable thermoplastic. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation.
Subcellular Localization:
Cytoplasm. Note=Associates with poly(3-hydroxybutyric acid) granules (PHB) when grown under 'storage' conditions.
Sequence:
MSNTNFFNDDWLELQRKYWDNWTDMSRKAMGLDSASSSATTPWEAAIDQWWKAMAPAAPDLSRSFMEKMMEQGKNFFRLADTFAKRADEGNAGNGLELWTKTLEDMQKRFSGSLDDGGNTMQRLMSFWELPLDNWQRMMSSMSPMPGDMLRNMPHEQFKDSLDRALSAPGLGYTREEQSQYQELMRSAMEYQAALQEYTNVYTKLGMKSVEHMGSYIQGVIDSGKTIDSARALYDNWVACCEGAYADEVATPEYARIHGRLVNAQMALKKRMSILVDENLGALNMPTRSELRTLQDRLQETRRENKALRHSLHSLERRVAALAGEEPATKPATALRSPAPAAKAPARRRTTKTNPAD
The following text describes a protein:
Function:
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MPGEPAISKPTEAERANTGDVKTPKTSTPVTKPHRHVVSAQVYDVLTLLFVFRFINALILRTFFQPDEYFQALEPAWNMAFGDQSGAWLTWEWQHQLRSSLHPAIFGLAYKAAHWILSALFPPALEMFVLEALPKLVQSVFAALCDYYTWQLATSIFGDESNVPWTALWMTVLNPWQWYCSTRTFSNSLETTLTIAALYYWPWDLVQDAKSNKQEEPLQVKGNLGSLRVSLILAAVAVLLRPTNLLIWLGVLTLTVTRLTLDGESPINRSTLLVLVKEIIVCGSAVLAVSLVSDRLYFGFWTFPPYKWLYFNISQSLAVFYGHMPWHYYLSQGIPLLTTTFLPFALVGLYKATSSSSSLTVLQSNILKTLSFAVLSMVGTLSIISHKEVRFIYPLLPILHILAAPYVFKFFTIPATSATAATTTQTKGNAAAASSPTTTGPVTLRHKISLANLLSLNLLLAIYLSLFHQPAALSVMTFLRTEFERIHPDSLSLDSSSSQKQELFALFLTPCHSTPWRSHLAYPALRARALTCEPPLHTQPGSQERRDYMDEADRFYKKSEEEDGLYGVEFLREEMWGGDGLTSGGGAQGEEIPRFIVGFEGIEESLKKFFEEDKKGKEMGIELKKVWAGWNGAFNEDWRRRGKLVVWDTGVYDEVVAEQKRSVF
The following text describes a protein:
Function:
Has antibacterial activity against the Gram-negative bacteria E.coli. May play a role in sperm maturation and fertilization.
Subcellular Localization:
Secreted. Note=Probably secreted into the epididymis lumen, where it localizes to the outer surface of sperm. Specifically localizes to the postacrosomal and tail regions of sperm.
Sequence:
MAAGSWKATRLLLAILVALVAFSYQVKRKTFIRIEEVSALESSVKETLEYVTDEYNKKSEDLYNFRILRILKIMKQVTGHLEYHITVEMQRTTCLKTETSLCDIQKGELHKKIQCYFSVYAIPWVEVFKILKKNCTDIS
The following text describes a protein:
Function:
Has bactericidal activity. Potent activity against E.coli ML-35, L.monocytogenes EGD and C.albicans.
Subcellular Localization:
Secreted. Cytoplasmic granule.
Sequence:
MRIVYLLLPFILLLAQGAAGSSQALGRKSDCFRKNGFCAFLKCPYLTLISGKCSRFHLCCKRIWG
The following text describes a protein:
Function:
Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can use FAD and ADP-ribose as substrates.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MLKAVQILGWSSGLTISQRLTKTRKSSTVSFISSSLNLSSVTSSSPRRIFSFKPTRMSSSLPGSDPVANSPTFVSVQSAGDVRKIKFCQWCGGPTKHEIPDGEEKLRAICTHCGKIAYQNPKMVVGCLIEHEGKVLLCKRNIQPSHGLWTLPAGYLEVGESAAQGAMRETWEEAGATVEVISPFAQLDIPLIGQTYVIFLAKLKNLHFAPGPESLECRLFALDEIPFDSLAFSSIYVTLNLYLEDLKKGKLKFHYGTINKRPGSSPSDIRAFSLDYHLQP
The following text describes a protein:
Function:
May be involved in cell-cell interactions. No carboxypeptidase activity was found yet.
Subcellular Localization:
Secreted.
Sequence:
MWGLLLAVTAFAPSVGLGLGAPSASVPGLAPGSTLAPHSSVAQPSTKANETSERHVRLRVIKKKKIVVKKRKKLRHPGPLGTARPVVPTHPAKTLTLPEKQEPGCPPLGLESLRVSDSQLEASSSQSFGLGAHRGRLNIQSGLEDGDLYDGAWCAEQQDTEPWLQVDAKNPVRFAGIVTQGRNSVWRYDWVTSFKVQFSNDSQTWWKSRNSTGMDIVFPANSDAETPVLNLLPEPQVARFIRLLPQTWFQGGAPCLRAEILACPVSDPNDLFPEAHTLGSSNSLDFRHHNYKAMRKLMKQVNEQCPNITRIYSIGKSHQGLKLYVMEMSDHPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGDPRVTRLLTETRIHLLPSMNPDGYETAYHRGSELVGWAEGRWTHQGIDLNHNFADLNTQLWYAEDDGLVPDTVPNHHLPLPTYYTLPNATVAPETWAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFRWLSTVYAGTNRAMQDTDRRPCHSQDFSLHGNVINGADWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHEKELPQEWENNKDALLTYLEQVRMGITGVVRDKDTELGIADAVIAVEGINHDVTTAWGGDYWRLLTPGDYVVTASAEGYHTVRQHCQVTFEEGPVPCNFLLTKTPKERLRELLATRGKLPPDLRRKLERLRGQK
The following text describes a protein:
Function:
Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate (By similarity).
Subcellular Localization:
Cell membrane. Cell projection, ruffle membrane. Note=In interphase associated with the plasma membrane, in particular with membrane ruffling regions. Accumulates in dynamic actin-rich membrane ruffles and microvilli-like structures. Recruited to membranes via phosphatidylinositol phosphate-binding.
Sequence:
MMGDHLRPMECLNICLEDNLQPCPEAYPSEIHGHPGPSEPCQEHTCPFDPPESARPDAPHGNSGVESTHLENCLVQVQARQASASLRSLEDNSSLGSPQQNQSSSTQVVFWAGILQAQMCVLDLEEELEKTEGLRAELRCCIPPPSKDLLGDEGLSPSRPEEDEDSGDDSSGPEEENQTWPREKIPGSSLEWGAEEDSIFFDNPLFLESPCSDTSTEGECFSWGYPNSHPDMKTWHQSPQTLDSPLQKGTGLWRQENELDLGSDTADHGGCSTPPFPVPSYKMHPCLALGSTEGDPTVPPDQEGETSCEDDLGHGSPKAPFVDHELIQESDNFEFDLRPATTHPVQPWGSQTSQSLSDLTQPILEDLQREDPSRSQETLISQNRGERDAGCFQEPVFCTLAPWGSQTSLLEPNCPESEGRGSGPQPSPVSSQDSSPRVLLHSPKWPQDASHLLQKDRSELSSLKEEETEEVPSLRQEAECEDTSRSEDASANQHHVHLASAEGLPESPMPQAQSPEEGWRPSSSREKLANDIRNDKGAWNLALRLYQLNGFRKSEVAAHLRKNNDFSRAVAEAYLSFFQFEGQSLDRALRGFLQALVLSGETQERERILYQFSKRFHYCNPGAFPSVDSVHTLTCAIMLLNTDLHGQNIGKSMSCQEFVTNLNGLQDGRNFPKELLKALYWSIRSEKLEWAIDEEDADRPEKDQPSPSAGKISSPFLQMAQDPTMPTYKQGILARKMHHIADGKKTPWGKRGWKMFHTLLRGMVLYFLKGEGQWLDGESLVGHMVDEPVGVHHSLASPATHYTKKPHVFQLRTADWRLYLFQAPTAKEMASWIARINLAAATHSAPPFPAAVGSQRRFVRPILPMSPVQSSLEEQHRSHENCLDAASDDLLDLQRNLPERRGRSRELEEYRLRKEYLEHEKTRYETYVQLLVARLHFPLGDLALWEDQLGKETDGSQEPRPSLKKSHSSPSLHQEEAPTTAKVKRNISERRTYRKIIPKRNRNQL
The following text describes a protein:
Function:
Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons.
Subcellular Localization:
Postsynaptic cell membrane; Multi-pass membrane protein.
Sequence:
MTIQALFFIVVFTGVGTSNPDFHDPQDRQLVSNWTTEFSSDNFGTIEPDYPNLGMAPLPPEAIDPLEIRPEHFNRIFKPFQGAKVDASYECSYQSVLNKLDLKKNTDKYVTTRPVADHRHLTWVFIEMRIYAILDVREADQMFISYIWVYLRWDNEHIQWDPDEFCGQKHILIPTKYLWMPDLTIEEMTEQDKATPSTHLKIKNSGWIEFRNDEVVESTCKMEVYRFPFDIQSCNISFKSIMHSDSELSLLEYTEDSELTEESRQTIQTQFEWIFISMSERKKTINHFGFNQTVVVYTISMKRRSVLYIANFLLPVLFFLCLDFASFLMSDTGGEKVGFKVTVLLAVTVMQLILNDILPPSSDKIPLIAIYCIGIFTLMLLSLLETILVMYLIDKDQTSTDKKEENQKLIENPEDKHSPLPCCCTGIKKRICCASAAKEDESFPKEGCSSPHTEVSLVMEKVYEELSEMKKSITLLSSSRTEDEKPGYWTRVAEKIDKVFIIFYILSVLLFLSVLFTLWNIDGT
The following text describes a protein:
Function:
Modulates cell morphogenesis by regulating cell wall formation and assembly, and/or growth polarization.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MPFYKQPWVFSKVFVLAMAKPPSFGCCFFLLFFSFLSSSFVSFALTDTEAAFIVQRQLLTLPDNGELPDDIEYEVDLKATFANTRLKRAYIALQAWKKAIFSDPFNTTGNWHGPHVCGYTGVVCAPALDDSDVTVVAGVDLNGADIAGHLPAELGLMTDVAMFHLNSNRFCGIIPKSFEKLKLMHEFDVSNNRFVGPFPNVVLSWPDVKYFDLRFNDFEGQVPPELFKKELDAIFLNDNRFTSVIPESLGESPASVVTFANNKFTGCIPKSIGNMKNLNEIVFMDNDLGGCFPSEIGKLSNVTVFDASKNSFIGRLPTSFVGLTSVEEIDISGNKLTGLVPHNICQLPNLVNLTYSYNYFSGQGGSCVPGGSRKEIALDDTRNCLASRPEQRSAQECAVVINRPVDCSKDKCAGGSSTPSKPSPVHKPTPVPTTPVHKPTPVPTTPVQKPSPVPTTPVQKPSPVPTTPVHEPSPVLATPVDKPSPVPSRPVQKPQPPKESPQPDDPYDQSPVTKRRSPPPAPVNSPPPPVYSPPPPPPPVHSPPPPVHSPPPPPVYSPPPPPPPVHSPPPPVFSPPPPVYSPPPPVHSPPPPVHSPPPPAPVHSPPPPVHSPPPPPPVYSPPPPVFSPPPSQSPPVVYSPPPRPPKINSPPVQSPPPAPVEKKETPPAHAPAPSDDEFIIPPFIGHQYASPPPPMFAGY
The following text describes a protein:
Function:
Catalyzes the formation of UDP-glucuronic acid which is required for K5 capsule synthesis.
Sequence:
MFGTLKITVSGAGYVGLSNGILMAQNHEVVAFDTHQKKVDLLNDKLSPIEDKEIENYLSTKILNFRATTNKYEAYKNANYVIIATPTNYDPGSNYFDTSSVEAVIRDVTEINPNAIMVVKSTVPVGFTKTIKEHLGINNIIFSPEFLREGRALYDNLHPSRIIIGECSERAERLAVLFQEGAIKQNIPVLFTDSTEAEAIKLFSNTYLAMRVAFFNELDSYAESFGLNTRQIIDGVCLDPRIGNYYNNPSFGYGGYCLPKDTKQLLANYQSVPNKLISAIVDANRTRKDFITNVILKHRPQVVGVYRLIMKSGSDNFRDSSILGIIKRIKKKGVKVIIYEPLISGDTFFNSPLERELAIFKGKADIIITNRMSEELNDVVDKVYSRDLFKCD
The following text describes a protein:
Function:
Component of sequence-specific heterotrimeric transcription factor (nfya-1-NF-Y and nfya-2-NF-Y) complexes which specifically recognize a 5'-CCAAT-3' box motif found in the promoters of its target genes to regulate their expression and control cellular identity in particular tissue types. In association with the components in the NF-Y complexes, represses the expression of the T-box transcription factor tbx-2 throughout larval development, which most likely restricts its expression to certain tissues. May act to repress txb-2 expression in conjunction with tbx-2 itself, which has an autoregulatory role. In association with the components in the nfya-1-NF-Y complex, negatively regulates the expression of the homeobox protein egl-5 to spatially restrict its expression in tissues such as the head. May regulate spatial egl-5 expression in association with the mes-2-mes-3-mes-6 complex.
Subcellular Localization:
Nucleus. Cytoplasm. Perikaryon. Note=Localizes to the cytoplasm of secretory cells and cell bodies of the small ganglia surrounding the pharynx.
Sequence:
MDPKPINEGMLLEDHDHGMPEEEEITEDDMNGIHNIEEDTRTISEIAMELHHPNKSQVLLDQERFLPIANVVRIMKTQMDPQAKLAKDAKECAQECVSEFISFIASEAAEICNITKRKTITADDLLTAMEATGFDNYAEPMRIFLQKYRQAHKITGPIHRTHPDYVRPPQFQMDPFVRPLFFDTEQGRRCTETQYVINGSEIVKNAPLGEEWNEQTGTLNTRADGYYMEEPMEPMPMEEVEIEEHEEIIEQDSLGAIALEQQGQMQIYVDPKTKQHFAAKETPNGMELYPLIIQDTPLQLENVSGPNQFVMNMPDGRAIPHGMGQEEPQPVSSSSVMRKIGQNPSSYAQQHHHVSHVEQHDDVEYEEEEEVDQVEEDTVPVPIAPRPAATRVQPKRTPTKRKK
The following text describes a protein:
Function:
Catalyzes the NADP(+)-dependent oxidation of D-xylose. Is able to use both NADP(+) and NAD(+); however, the enzyme shows a very strong preference for NADP(+). Is likely involved in the first step of the oxidative D-xylose degradation pathway.
Sequence:
MTKTAIVRVAMNGITGRMGYRQHLLRSILPIRDAGGFTLEDGTKVQIEPILVGRNEAKIRELAEKHKVAEWSTDLDSVVNDPTVDIIFDASMTSLRAATLKKAMLAGKHIFTEKPTAETLEEAIELARIGKQAGVTAGVVHDKLYLPGLVKLRRLVDEGFFGRILSIRGEFGYWVFEGDVQAAQRPSWNYRKEDGGGMTTDMFCHWNYVLEGIIGKVKSVNAKTATHIPTRWDEAGKEYKATADDASYGIFELETPGGDDVIGQINSSWAVRVYRDELVEFQVDGTHGSAVAGLNKCVAQQRAHTPKPVWNPDLPVTESFRDQWQEVPANAELDNGFKLQWEEFLRDVVAGREHRFGLLSAARGVQLAELGLQSNDERRTIDIPEITL