lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Probable transcription factor that may function in salt stress response.
Miscellaneous:
MISCELLANEOUS: Seeds over-expressing MYB74 display hypersensitivity to salt stress during seed germination.
Subcellular Localization:
Nucleus.
Sequence:
MGRSPCCEKKNGLKKGPWTPEEDQKLIDYINIHGYGNWRTLPKNAGLQRCGKSCRLRWTNYLRPDIKRGRFSFEEEETIIQLHSIMGNKWSAIAARLPGRTDNEIKNYWNTHIRKRLLKMGIDPVTHTPRLDLLDISSILSSSIYNSSHHHHHHHQQHMNMSRLMMSDGNHQPLVNPEILKLATSLFSNQNHPNNTHENNTVNQTEVNQYQTGYNMPGNEELQSWFPIMDQFTNFQDLMPMKTTVQNSLSYDDDCSKSNFVLEPYYSDFASVLTTPSSSPTPLNSSSSTYINSSTCSTEDEKESYYSDNITNYSFDVNGFLQFQ
The following text describes a protein:
Function:
Inner nuclear membrane protein. Acts as a negative regulator of the BMP (Dpp) signaling cascade during crossvein development in pupal wings and possibly during synaptic transmission at the neuromuscular junction (NMJ). Appears to be required for pupal development and consequently transition to the adult stage. During pupal development, plays essential and redundant functions with the other LEM domain proteins; bocks and Ote.
Subcellular Localization:
Nucleus inner membrane; Multi-pass membrane protein. Cytoplasm. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, spindle pole. Note=During anaphase and metaphase, detected in the nuclear envelope and spindle poles.
Sequence:
MSTESLNSLSDKELHRKLIQSGFPSTPVTETTRAVLIEKLRKHTRADKLKKRSNKYVLYSKEQQESPPFPQYHQYHAPQPPQNYANGLDNNNDLDQTGGSSAYNRSLDESDSSPLQLSASKMYAPPPVVASNYDGDCSPHSLGLNGKYLQPCSMPYAIDTSNNYGKPSGKAKLSDGGVVNRLLSFRDTTIQRKFNYPTGQASRIPLRKERLTRFALSDLKSFIRNPDIRPYVIPRVLISLFLIFLTIITVLYVGKRFEQSPIDKAALKYTLCNPNDMQMISEKVNCIEKDSLRGALDMSEELFRHLNERARLHHCKDANLSPALEIGEFVREMVSNPKTHRGNLHSNLMAAKYLITENPQWSIQVVDSTKHLGQTSHFELSEPNLPLKCIVLKKVTRFFTVIGALLLIVAGFLIVYVAVVIYRVKQKEALLAVDQFQKDIINELIYLSSQSESPEVVINQLQEKFLPAKKRSKLLSSWNKALKQLEKNDSRVLFGMVNRDGKAMRTIAWNRNVDKKDVGLVKKWQSPAFDNSNKIANPPTPCLKIRHMFDSSEVDQANLKQSIVESIIEKVGTRCKICDVQLDVQSCCVYIRCASEEDAGTIHKEINGWWFDKRLISIKFLRLERYLSRFPKPSAEPLYFHTNEAANTHS
The following text describes a protein:
Function:
Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
Subcellular Localization:
Nucleus.
Sequence:
MARTPRVRPTSPSPPPGSPSDKENLENPSSKKRGIQGQNMSSSRKSTKRQRLGDTASNIETGTQISQAQRKASTKYYDPDQDAAERRRVRKGLRDLTRDLNDSRNEYLQPGNTGIKDTFLKANEIFRDVKQTSDATIDSRLLVNAADLSYKKAATLALGESGVGIDVDEFVSKCISFMRAGPEDPNVSITSTQRRRAPRRTQADMDSDDEDGDAMNWDWLGRAACFRHSSRPAVSGFLLGPLSVQKRTRQIAQRRARERIDPSQAVRPQELREEDLDRRETTNLTAMCTSINKLLGKTRDQAERLANEALEKIGDPTEDEVQSIMAKYNIADDAGVPLANFCINPKSFGQSVENLFYLSFLVRDGTVGISTDSRGLPTLHPTKPLAPSEAQRRGVQKHQSVFSLDFDTWKDMIDAYNIKECIIPHREEEENDTAQGWYS
The following text describes a protein:
Function:
Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits. Can bind around 60 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2; this plays an important role in triggering muscle contraction. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats.
Subcellular Localization:
Sarcoplasmic reticulum lumen.
Sequence:
MKVASLLLVGFYLLPSCRAEEGLNFPTYDGKDRVINLNEKNYKQILKKYDLLCLFYHEPVSSDKVSQKQFQMKEIVLELAAQVLEHKDIGFAMVDAKKEAKLAKKLGFDEEGSLYILKGDRTIEFDGELAADVLVEFLLDLIEDPVEVINSKLEVQAFERIDDFIKLIGFFKSEDSEHYKAFEEAAEHFQPYIKFFATFDKGVAKKLTLKMNEVDFYEPFMDEPIPIPDKPYTEEELVEFVKEHQRPTLRRLRPEDMFETWVRKWKSLLALRYGHARQREDGFEFLEILKQVARDNTNNPDLSIVWIDPDDFPMLIAYWEKTFKIDLFKPQIGVVNVTDADSIWMDIPDDDDLPTAEELEDWIEDVLSGKINTEDDDDDDGDDDDDDDDDDDDDNSEEDDDDDDDDDDDDSDDEDE
The following text describes a protein:
Function:
Hydrolyzes phosphonopyruvate. Not active towards phosphoenolpyruvate, glycerophosphate, phospho-L-serine or phosphoglycolic acid.
Sequence:
MTKNQALRAALDSGRLFTAMAAHNPLVAKLAEQAGFGGIWGSGFELSASYAVPDANILSMSTHLEMMRAIASTVSIPLIADIDTGFGNAVNVHYVVPQYEAAGASAIVMEDKTFPKDTSLRTDGRQELVRIEEFQGKIAAATAARADRDFVVIARVEALIAGLGQQEAVRRGQAYEEAGADAILIHSRQKTPDEILAFVKSWPGKVPLVLVPTAYPQLTEADIAALSKVGIVIYGNHAIRAAVGAVREVFARIRRDGGIREVDAALPSVKEIIELQGDERMRAVEARYLK
The following text describes a protein:
Function:
Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MKIKKYVAESIREAMIMIRRELGENAVILSSRRIKKGGFFGIGGKTYFEVTAAVEEERKKEENTSYRLQEILVKNRQSSNDNIKGEFDEIKRTINEIKQMLVTEKRQTLPEGLSKILYGMEKQEILPEIRYKLIDFLKMKFGDLDPNSNETFKILSEQFVNLVKTNAPDFKNAKVLFVGTTGVGKTTSLAKLAARFKIDEKKRVAILTLDTYRIAAAEQLKIYADIMDIPMKIAYTPKEAEYEMMALKDYDIVLVDTAGRSHQNDLQMSELRALSEAVKPNITFLVLSMNYKLDDMKRIVERFSAVKPTHIILTKMDETSVYGTFVNISEITGLPIAFVTNGQRVPDDIFEANPVELARIVAGEVLNHARSSGTSEKE
The following text describes a protein:
Function:
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MSDADIEASKAPLMDHLIELRSRLIKALLGFGVAFIFCFFFAKQIYNVLVWPFVWVAGPENSKFIYTALLEYFITQLKLALFGAGFISFPIVATQIYKFVAPGLYKHEKQAFLPYLVATPFFFVLGAALVYFVVLPMLVRFSLGMQQAGSDETAQIQLLPKVGEYLSLMMSLIFAFGIAFQLPVILTLLGRIGIVTSKMLREKRRYFIVIAFVIAAVLTPPDVLSQCSLAIPLLALYEGSIIAVAMVEKKAAAAQAAAGTDVSTPANPAE
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1); S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.
Subcellular Localization:
Nucleus.
Sequence:
MEEQHQSKRARLEEDADTFDGIGVVVLIGDQYNEFQDAQPNYQEIPGNYSNVAKKLMAKMKYTPGEGLGRHSQGRRNIIEASKQRGHRGLGSENKHFQQDEDTEWSVDDEQINIEEMATWIDECQLPLPDRATLDSWMKIGKKKMTIDDEANFCEPNILKDVLECKDMFDELESKEMVEARTRANPYETIKGAIFLNRAAMKMANLDYVYKYIFTNPRDDKGNEKIRSLDILYFADICAGPGGFTEYVLWKRRWHAKGFGITLKDPKNASDFKLTDFLAGTPETFEPYYGVNGVNGDGDVTRTENLRAFAEFVRSSSEGGVHFAMADGGFSVEGQENIQEILSKQLYLCQFLCAISVLREGGNFVCKLFDIFTPFSVGLLYLFYRIFRRISLVKPLTSRPANSERYIVCEGYRNADDVRDYFYSVNDKINELKLAERKEAVVFTTSYKRSEKTSGSEEDYFNTSENENSNQLSDSEIESDQQDEELGAELMTNALQDDRTIIQDKSSKHNLDVTEVVPLDVIRGDKAFFEYVVQSNNRINSSFQNSIGVAQVYALRKIQAFAKNRFQLDYFIPTNPRSKRNIPSPRDTFFKLLNTSLDDWETNNRIIEVTKSTIKRMTAIYNYRFTISGGRRYFILSLSGKFIYRTSFDKYGNMDVNKWEELSNSENRINLEMPENTLIEAEIVTEYRGEGKSQKHVNAIHIVDIAFLGGDDYRNFHIKERLRYAEKFVKALQKKSINTATPLRVKLLHRLNDSSTILARLQSKKMKGSRGRKNCCIVGSDKSDDSCFFIPTGLYIVKDILDPWVVRISNTHNRYYFFNTANNSSQYDLPQEDIASFRQCHELRLFWPWDDSNDFVDSNTAKIKGNRDDKVSKDELLDFIKVTLSGGNR
The following text describes a protein:
Function:
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of enzymes involved in arginine catabolism. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for the receipt of the melting signal from the remotely bound activator protein GlnG(NtrC).
Sequence:
MKQGLQLRLSQQLAMTPQLQQAIRLLQLSTLELQQELQQALENNPLLEQTDLHDEIDTQQPQDNDPLDTADALEQKEMPEELPLDASWDEIYTAGTPSGPSGDYIDDELPVYQGETTQSLQDYLMWQVELTPFSDTDRAIATSIVDAVDDTGYLTVSLDEIRESMGDVEVDLDEVEAVLKRIQRFDPVGVAAKDLRDCLLIQLSQFDKSTPWLEEARLIICDHLDLLANHDFRTLMRVTRLKEEVLKEAVNLIQSLDPRPGQSIQTGEPEYVIPDVLVRKHNGRWTVELNSDSIPRLQINQHYAAMCNSARNDADSQFIRSNLQDAKWLIKSLESRNDTLLRVSRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHSPRGIFELKYFFSSHVNTEGGGEASSTAIRALVKKLIAAENPAKPLSDSKLTSLLSEQGIMVARRTVAKYRESLSIPPSNQRKQLV
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence:
MKIPNVSTPPAVPSLTTKPLTVTKTKPKAKEEPQEPPQDMSLHLQQLMLSTDNVQNNSFSEDFLEQLVPIVKDAIKTKRTGELLDRLDGITRLQDRKLEQLCEGGQGDYLVSMPKLSQIRSGADRQRGALQDLNFRLQQSGGQLVTRKKRLLEARTVRENLDTAIETVESCLQVLELTNKTHDLIKAKKHFAALKSLDDLQNVHLKEVSDYGFARMINDSVPQLTSLVQEDVVNDTFKWLSSLRSVYPAIGQAAFQETERLRQEWRDEVHRNPELARYKFNSPIELSYRSSSFDPIDNHSVLVELDPLYECLHIHHTLRKTDVFIKKFDEFRRSHVQNIVPTVASMSSASEDGVAEILQNLAGFCILDRTISSRTTKGFRPQSDVDDLWISLSQKLMGTLGHELASVQDQAVLVNLKAQLGLFVQTMEQYRFDTVNVGDFLLLSFRKFSQFLISGFDKDFNTGIMEDDTNKITIHDADRYEKITRACWWTPADDEAAGGKPGAATDGVFPKTLPFSPILPLCCAKITHLIHQHYAFLDEFNVSEVTQTEDYVQQAMDSLLNDIICDTLLHRLMTTTREQIVQILIDLQQFERVIPFIAQSIVDGRPSQRKSKITLKAQKKFQQASAKAESRIFEHVTQTVDNFMELEDYDWSTTVSSDEPSSYLDEMVNFLTIFFNSTLADLPFAIKNYVYFGAFDHLASSLLQILLNAPRGLITTEAVHNYNVDIQYMEQFVTTLHLDGGNASLSTTFIEIRQCLDLLMTNELSKEYNNPQIRMRRYDRIKPEVAQQLMDMSQTMKQPQSPQIGGGTQQKPTSRFMRMYRNASGAHEP
The following text describes a protein:
Function:
3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'.
Subcellular Localization:
Cytoplasm. Cytoplasm, P-body.
Sequence:
MSKVEGLGTIVQETPSPLKPVGFTPTATGGKFGAASAIKSTPKKQQPYINKSQYSPQVNKNPRKIFAEYISKEDSDAGIKDSSMFRAVLRINPKNYQECFLDHPKGSSYPDVLVLGQDRNRAMQGDVVIVKLKPKEEWLVNYVEYVKWWGQNKTETRNLGKTDNNTNKSEKRCLRDEINDNGVGVDEVPENCLITVGAIVRIDEKKHFRVAAGKLQQMPNAANPNVLFVATDSRVPRILIPKSEVDQEFFSRPKDFERFLYTAQILDWRADSIYADGKLIKLDECIASLPLTTAEAWKIPDSEFNYRRDFRDDIVFTIDPKTARDLDDALHAKHIDDCDGKGTPGIEVGVHIADVSYFLKEGTELDKWASQRGNSTYLSQIVIPMLPRILCEQLCSLNSGVDRLAFSTVFKMNYEAELKDVWFGRSIIRSRVKLAYEHAQDFIENPEKDFTADELPEISDGNMPSEIKEKTLMLHRIAQLLRQKREDSGALRIELPKLKFVMDEEKRPQGVSIYEVKDSNKLVEEFMLLANMEVAKKIATHFPDTALLRNHPPPKEKMIEDAVEQCKRIGFQLDGKTSAMISTSLRKYQGKSRLDMCIRQVISSLTIKPMQQAKYFCTYGKDLEVYHHYALNVDHYTHFTSPIRRYPDVIVHRQLAASLGYEEKSERKPKEIKDICIRCNDTKQASKEASEESAMLYFGVFIHSTGKMNCQAVVLGIMDLSFDVLIVDYGVVKRVYVDVSSMSLFILHQLSLFQKMKREYVKQDEQLVLYWPADPNAENGNKEEFSTVIQMCSVVTVLLVPVKEVEVSAIMIRPTLDKRKVLESTLKDMNFQSLLLISVSF
The following text describes a protein:
Function:
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
Subcellular Localization:
Cytoplasm.
Sequence:
MPRYQGQSGSPGIAIGPVFVYHSQQVTISEHSADDPISEWRHLQHALQQAHTQLIALEERARKIAGEEEAVIFAAHRLFLADEELLATLRTMVLREHRNAKAAVYKAFEQYAEALSNLEDEYFRSRAQDVRDVAHRVLRCLQGSEKEEKAGEIVEPIIVVAEDLTPSDTIQFDRDKILAIVTSRGGPTSHAVILARAMGIPAVVSVPLELSDIRNGTLAIVNGNSGLFNVGPTLHELEIARKEKELIDSRYQFVLSQATLPAVTKDGSFHPEIVANIGGVEDAKSAIDFGAEGVGLFRTEFLYLQRNNVPTLAEQVRAYQDVLKVMGNRPVVVRTLDIGGDKEFPYLGTQKEPNPFLGWRGIRTIRERPDILEQQFIALLTAVAQTSTSGTGSDLRIMLPMVSSLAEVARAREIFEEAQTCVRAQGLPLPDKIQFGIMVEVPAAALLADRFAPLVDFFSIGTNDLTQYTLAVDRTNERVSVLASPYHPAVLHLIDKTIRAAHTAGKWVGLCGELAGDPLAVPLLLGLHLDEFSMAPSFIPIIKDIIRQWSLPAAEAVAQQCLQFSLAADVIEYLKQQQPH
The following text describes a protein:
Function:
Minus end-directed motor protein that transports actin filaments along microtubules. Plays a central role in the polar orientation of actin filaments along microtubules, and thus a contribution to the organization of the cytoskeletal architecture. Links the actin microfilaments with the cortical microtubules in both cycling and non-cycling cells. Required for efficient cell elongation by its participation in the premitotic nuclear positioning.
Subcellular Localization:
Cytoplasm, cytoskeleton. Note=Colocalizes with cortical microtubules and longitudinally oriented actin microfilaments.
Sequence:
MMAAAVEEEEMVERMHGWARDMDVASRRAEEEAMRRYDAASWLRSTVGVVCARDLPDEPSEEEFRLGLRNGIVLCNALNKIQPGAIPKVVQAQSDAAGPTDGSALCAYQYFENLRNFLVVVEDLRLPTFEVSDLEKGGKGVRVVDCVLALKSFSESNKTGRQASCKYGGLSKPLTARKYFILKNTDAFMNKIMKGHSAEAIQSEFSEGQSIVTDFSIESNEMTTSDSLSILLRKVLLDKKPEEVPLIVESILSKVIQEYEHRIAIQNKMDEEEQNLLNITEQVNHVVVNGDGEVKQFQLEAQTNFDVQQKQIQELKGALSFVKSGMEQLRLQYSEEFAKLGKHFYTLSNAASSYHKVLEENRKLYNQIQDLKGNIRVYCRVRPFLPGHRSLSSSVADTEERTITIITPTKYGKDGCKSFSFNRVFGPASTQEEVFSDMQPLIRSVLDGFNVCIFAYGQTGSGKTFTMSGPKVLTEESLGVNYRALNDLFNIKAQRKGTIDYEISVQMIEIYNEQVRDLLQDGGNRRLEIRNTPQKGLAVPDASIVPVTSTADVVELMNQGQKNRAVGSTAINDRSSRSHSCLSVHVQGKYLTSGAMLRGCMHLVDLAGSERVDKSEVVGDRLKEAQYINKSLSALGDVIASLAQKNSHVPYRNSKLTQLLQDSLGGQAKTLMFVHVSPELDAVGETISTLKFAERVASVELGAAKANKEGSEVRELKEQIATLKAALAKKEGEPENIQSTQSSPDMYRIKRGNAIPAFPKNRQPMEEVGNLEVRNNATPMQKKASFQFSGVLSENNSSDLAENCNGIQKTDRMAVGNNQFENGNSILELEPGATQLPTFFYQRYDPDKQRRRAEPVETDDSDSFDAATSSPSDQEMLLSTSGLKADGIASRGAFIIKKPQTKNTKITATKIPNLAMKSPMSEKRLQTPIRNSKQLPFSTTGGRRTRNGKINTPK
The following text describes a protein:
Function:
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
Subcellular Localization:
Cytoplasm.
Sequence:
MDAAAQTSLVVSEDRRHPANVICALCRLFYANNWVTGTGGGISIKHPATGHIYIAPSGVQKEQIEPEDLFVLDGVDGAYLRAPAGHRPSACTPLFLACYRARGAGAVIHTHSQHAVLCTLLFDDVFRIANIEQIKALPSGRRDAAGKPLSLSFFDTLEIPIIDNTAHEEDLAPGLEAALARHPACTAVLVRRHGIYVWGPTADRAKVYNEAIDYLLELAVHMHRLGVPPDCPIGEEKRFLRR
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence:
MGLFDGLPVPKDKEYLREDLENVDESWTVARFDSLPHVVHILTSKDRDGEIQALKDQSDIVEEVVDEVVQTYHSGFNRAIQNYSQILRLFSESTQSVGKLKVDLGNAKKVISARNKQLHQLWYRSMTLRHIISLLDQIENIAQVPTRINKLIDENQLYAAVQVHVQSARMLEREGLQSVGALQDVRSELAKLRGVLFYKVLEALHAHLYNTGEYSSATPSMNEKDDAIPTTTVAAFSMNNSQSLSRRTRLQKGDSHVGASGFASSVDGGSSYDGHDDDDIDGADNAKNVPRLPAWLSESTPDEFVETMRKSESPLHVKYLQTMVECLCMLDKVAAAGAIICQRLRPTIHEIITSKIKSQAEYVNSSRPGVGHAARTATIGLEYVKGHLHKEQHKNGTSLVGSLMAVSPVTPVMAPMGAAQCAAKELLDLILDTVVRIFDNHIVVGELLESKSSQQAPKATVREISGNLDSEASQATGGYTIGFSMTVLQSECQQLICEILRATPEAASADAAVQTARLASKTPSKEKRDKSEDGLTFAFRFTDAAVSSQGADLMRQGRNRKGQNVQEGYGSASILPEQGIYLAASVYRPVLQFTDKIATMLPEKYSQLGNDGLLAFLENFVKDHFLPTMFVDYRKGVQQAISSPAAFRPRANPTAAYTPSVSKGRPILQGLLTIDFLAKEACFFFFRSLFSSKMPFSSLRLVQFCDFRPKVFFPHVLGWAQAMPKFSGDLVKYVQTFLERTYERCRASYTEAWLILFSLALHLPMLHAVLEKQSYMLIGRHDVENLMRRDPASTFLPTSLAHANADNHIADAENDGVELQISELLMKLRPIKQESLIRDNNKLVLLASLSDSLEYIADSIERFGNVAGKASETEIDLKPTPVHHKRNSSLPPKDLAAFAEDYRKLAIDCLKVLRVEMQLETVFNLQVMATREYLEDQDAEEPDDYIISLITQITRRDEVIAPFIAPTKRNYIFGGICAVASHASIKALAEMKHINLFGVQQISRNTIALEQALSAIPSIDSESVQTRFDHVRTYYELLNMPVEALLAFITEHDRLFNPIEYYNLLKVQVPGREVPDDAKARMADILPI
The following text describes a protein:
Function:
Acts redundantly with CYP98A9 as tricoumaroylspermidine meta-hydroxylase. Also catalyzes the meta-hydroxylation of the three triferuloylspermidine phenolic rings. Unable to use 5-O-(4-coumaroyl) D-quinate or 5-O-(4-coumaroyl) shikimate as substrates.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MIIYLISLLPIIVATLMLYQRWWRSNIPPGPKPKFLLGNLHQMKPLWTHSFSEWSETYGPIISVWIGSQLTVVVSSSDLARQVLRDKDHQLSNRHRIARMTQTGTDLVWSDYSPHYVKLRKLCTLELFSLKSIENFRSLREMEARSMVVSILKDLMSNSGDDQERKPVIVRKYLAAVVLNTISRLMIGKEFGSEEGKEFKAIVEKEHLLSGSGTILDHVWWLKWVSSWFFSDKEFLAHKDRRTKWFRGAIMVEEDIEIEDHRGFVRKLLVLKEQKELSEETVGGLVWNMLTAGADTTAVVIEWAMAEMIKCPTVQEKAQQELDSVVGSERLMTESDIPILPYLQCVVKEALRLHPSTPLMLPHKASETVWVGGYKVPKGATVYVNVQAIGRDPANWINPYEFRPERFLQEETDVKGRDFRVLPFGSGRRMCPAAQLSMNLMTLVMGNLLHCFSWSSPVPGERIDMSENPGLLCNMRTPLQALALPRAAARAIPLPLD
The following text describes a protein:
Function:
Inward rectifier potassium channel that forms the pore of ATP-sensitive potassium channels (KATP), regulating potassium permeability as a function of cytoplasmic ATP and ADP concentrations in many different cells. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium. In pancreatic cells, it forms KATP channels with ABCC8/SUR1. Can form cardiac and smooth muscle-type KATP channels with ABCC9.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MMSRKGMILKEFLLTTRLAEDITEPKLQAQERRSRFVAKNGTCNVAHTNIREQGRFLMDVFTTVVDLKWPYTFLTVTMSYLCTWLLFGMIWWLIAFAHGDLDINEETFVPCVTSVQSFTAAFLFSIEVQVTIGFGGRMVTEECPSAILVLIIQNIVGLVINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRNGKLCFMFRVGDLRKSMIINATIHMQVVRKSSSQEGEVLPLNQIDIQMENPISTNGIFLVSPLIICHTITKDSPLYDVSPNTLTHHQDLEIIVILEGVVETTGITTQARTSYLADEIHWGQRFVPVVAEEDGRYCVDYSKFGNTVNAPTPHCTPREMEENHSAQDNICFSPRGTVRRRNKSMRVKPKFTLFEETS
The following text describes a protein:
Function:
Formins play an important role in the nucleation of actin and the formation of linear actin filaments.
Domain:
The DAD domain regulates activation via by an autoinhibitory interaction with the GBD/FH3 domain. This autoinhibition is released upon competitive binding of an activated GTPase. The release of DAD allows the FH2 domain to then nucleate and elongate nonbranched actin filaments (By similarity).
Sequence:
MVKLFGKSKKKEESPQSIDIAFQSILDEIGVVETEKKHLMATMDTVRKQQLIQSYSSKKFSKNEFGNKSKKKSIITQSPHYFVDCLKNDPSKEVLTSLRVRLGNQPLKWLKEFLSLDGVSLLIKVLILNEIKQVKNQEDIYKIAQCLHSLKLIMNTKFGLESVIKQPTNIHSISLVMDTPHLKTRIMVIELLAALCVVNSKGLPLVLSAMDNYREVKREKKPFIHLFQGLKNPSGSLQATTFALINTLISSSQSVEERQKIRNQFKKLGITKVIEELEPEYANNPDLATQKDLYEQECRWDEQEQIENARGDISDENPEALVKAILDRTAGGPLYSSFTSILRLLANSITDQTKDQSLSNYLFVEKVIGKMNNGESYLDDIGTFFGGGGGGDGSLDIAHVSGEKAVLIQKEIEDLKKQKKRDQDKLAEKDKLLTKLAKRMRKMEEAIKLGKGLEYLNNQIEIESPPDSSTSTPQETTPGGTKVPLKTSPVTKADLKHKLSTFTTAKAPNGVSDFLSGLDTTNQQGSTDASQTEAGSGDGIPLPPGAPPPPPPPGGKLAPSTPQLCSRPPSIKMKSYQWTRYRTRNVTNTFWKNVNLTKYNDCLPHEQIEGLFGAAIFEKKEKELKKGSEVTVIDTKRAQNIGILLSRFKNVTHDAIYDAIYSLDESILDLETINQFIKYIPSKEEIDCIIAFKQQQEQLPEEERMKLGKSEIFIDKISTIPRLEQRIQALHFKLNFPDKLYHAKPDIRKFNEAFVQLQNNNIFAIMELILSIGNFINFGTNRGNASGFKIDSINKMADTKSNIREKYTLVHYLIELLESTQPELLKVFDEIPSVVDAATLSFNQSSSEIKLLRAGLIKLEKEIFVRQPKSVEPKPDDETINNNGEDDINNTSSDEKTEGQQQRQGEEEENDESESTGNSFADSLKKKKSQVNTNSTSDSKQSLEPLKDDDPLKLKLSEFLLASKTELDDTETLIAETEVLFKSICKFFGEDSTKIQPEEFLAIFKKFNDKFIMSKKDLEIEKSIKDKSTQRKNEKERKEMEIKKSKLEMIHSKLKKIGSPSSSNRILASNESSPTSSTSSVVHQHDDEDEETIKEYINNPSPSQQSNSSEEEGMMDDLLNLIRDGNFRELRRMNLQQKKPVRTKRVIAKQPTRPQALDTPSSTYSSISSIYDAEPLDMSDQEDEDEEEEEDEEEEEEEEEGDDDNDNDEEEGEN
The following text describes a protein:
Function:
Interacts with OSBPL11 to function as lipid transfer proteins. Together they form a heterodimer that localizes at the ER-trans-Golgi membrane contact sites, and exchanges phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine, PS) for phosphatidylinositol-4-phosphate (1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate), PI(4)P) between the two organelles, a step that is critical for sphingomyelin synthesis in the Golgi complex.
Sequence:
MSSARPNALGLEGPLSKWTNVMKGWQYRWFVLDQQTGLLSYYTSRDKMMRGSRRGCVRLKGAIIGIDDEDDSTFTVTVDQKTFHFQAQSAEEREQWVTALEETVLRHKQAPKYGLPLPRTTPSVRDFERKLFEADAYLQILITQVESLEDRINKMQNAQERTHHEKLQENGKAMIESVKQAIVLLQVAKNTLNPVNGFLQPEMLLDDDNTTTANVPSQHKKGSPDASIDSAEEVLEAHMSPHLLLHSATMAAPVSPMSSAPLSMIRHPRQDIPVLSYSSSDEDDFFDADEYQEGEENDKVFHRNPEKVEERLMQNRARQDSCPEDEDSIDLQKHGSIITHLLSQVRLGMDLTKVVLPTFILETRSLLEMYADFFAHPELFADISDIDNPRERMVQVVRWYLSAFHAGRQSSVAKKPYNPILGETFQCYWDLKGDSPAESVKNEVPEGPVPWAGSDQVSFMAEQVSHHPPISAFYAECPDKQMSISGHIWTKSKFLGLSIGVEMVGQACCSDLKHEEEYIMTFPNGYGRSILTIPWFELGGKCNINCAKTGYSALVSFQTKPFYGGKKHRVVAEIKHVSDYKPFVTVEGEWNGVMTTKGASGEPIVFVDTKEMKVNRKRVRPVDNQDPYESRKLWKDVTSNLKTQEIEAATDAKHFLEERQRREAKERLAEGTKWDTKFFHEDGECWIYDNPLLKRVQAQKARSAKNATPSPQHTPTTKGKLSNHQNGIDTASTGHSSPSLAPSQVSATASSPQKAASQETQDLLQ
The following text describes a protein:
Function:
Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.
Sequence:
MYHRNSLSARGLTRSLVQLVSAARPTSFPQVQPQAIINKSNKVLFSRTFFDLPSFPPSKPSESEVQSVEDLYAKDRLFSKKGDLLVYKETKRLPYTKEQLYGVIADVEAYPQFVPFCTGSNVYSVETLGDSSSSERPKDNRARPWLEGGYSGEIHLLQKELSVGFKGIEEKYISHVECRKWDTVKATASNSKLFKHLTSTWTFKSPAEISFPQSVLQTNDPSSSNSTYISLHLAFAFASPVHAAISELFWKAVSERMVSSFEARVRQVHGRPTQKC
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Sequence:
MELQDPEAGEAPLAEVMGIQFGILSAKDIVTLSVFEREHSIITAKDLWDSRLGIYNLPGNNNHCQTCGARKASDCDGHFGHITLPMPIYHPLHIYFLKKLLNQICLVCKRFKEKEFKKGTFEEQATWMEMKRQLNISEFLDIASNWETDATKKAYVLKTKCKIEALNSQAFALKRNWAHISEKLTRKSQLLNTTSSEILSTHVASYIDSAYADYLVEELDSSESSDDGKACKWCGANIKNPKDRYPNLVVTLSKMKDNSYETIEMKASVKEGKLPLDYWNFVCGNPERVNNTRPLLPFEAYNILQSLSKKVIQKLGMDEYVARPEALILHFVPVPPSGSRITEVDFGSSLPRTHMDKQHKLLQRLSFEVKRLQSLRTGMPDWATTKNEVMELQLLASSYLTGSKWEHGLNPKAYDAVVKSDVQKSDRYMKGHILAKTNNSSARMIVVGDPSIKIEEILLPVFLVEQLTIPEKVTAFNIERLQRYVDNGPYADLYKTGAVFHDRPGRDRVRLHSRLKRMVVEIGDTVHRHIKDGDLVIVNRPPSLTKHAIMAMEVRLHHSCSLAINPLICAPFQADFDGDCMHLFVPQTSEAHAEAHELLKVSNQLINPQGGQSNSALTEDSRLGAYLMTSSCIFLNKMEVSQLSTSSLVSLPIPAILKSPNKREPLWTGQQLYSTILPEGICYKVTDKKFSTDVERGILISNGELLVCNGNSNWLGDAFDALTAVIHTSQGPAAALVYLNRAQELANLFLRDRGFSVGLQDFQLSRDRSQLLRRRLEEVSIGNREALFRTLLMDEHVQREELNKNPASKRGLTAETECIKSKGLYLGATGIVKQVEALDKVAVDRFQTKFRESTKRLAKDYCKRMNPLLVMINAGSKGSMSKLVQQTISVGLQLFKGEHLLPLNVPDFCQKQLTDVSTLRATDFLQFERRVPSANLSGYWESRGIITSSYLDGLSPLQFFIHTLSSRYGIMRSKVEEPNLLLKRLLLFLRNLYVEYDGSVRSLEGQQIVQFKYGRYIEGQRGAITTLEGPKIWCEAGEPVGILAATAITEPAYQLKLDSPHNVGAKAIGPLDLINETLSPSNPLKLIDRRVLLRFPLALKSRRHGQENGAMRILQHLKPVSLSMVATTTMIEYRKAQTVVGEHGRSSPWVGHIRLGVVKLKIYQLLVADLVGSLETQYTNCKFASSHSCQFGSSGVTQEQPNPCIHFFVDDSTLVATLDDKEYDEVLSNSLEVMKNVILPILLRTPIKGDARIESVNLLWEDMEWNPRCTKYLSSKKPCKNGTGELVLEVTVKKECCKSRGKAWKIVTESCLPIMQLLDWQRCTPYSIQELNHVFGLEAAKGVLLQRLELAIAGMGKPVNLEHLELIADTMVTSGKVSGASLSGYKDLCKTISRSAPFSTAAFLNPKNSFVVAGRHGISETMEGALSSSVWGKAPSLGTGSNFEFFWQAKAREREVCNIREGFDIHEYLAKLNSSALKPCEGVPVPQHHNESQCVSTTMIQGHCDMVMSPDDFKLKQTNDELEIHLRSKEDFPQVGNHNGVLKQQASSPTHISHPPVTDPIRTEGAVTSRSEACEDSSSFHTPNETLELTRQDSSNSSPCSSFRKDLFPTPVLHDDSEGDETSGIV
The following text describes a protein:
Function:
Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
Subcellular Localization:
Nucleus.
Sequence:
MRKKNKGRVSETPISGPPETLIQEKHGFFACYLLCSLSPRHKGHTYIGFTINPRRRIRQHNGEIGCGAWRTKRKRPWEMVLCIYGFPSNVSALQFEWAWQHPTESLAVIGAAASLKTLSGVAGKVKLAYTMLTLPAWHSLNLTVNFFSTKYLSYSAGHPTLPEQMNVLVRSMDELPCYLEGWVLDDDNDDDEGSHGHGHVHIHYDASDLDNNKHSINDLLVGNKRKKNHKGTLKDVHPRCEDGVHYDGIQDHCDGQFGINDTPIQGGDVIKTLRGTLSDDDAHCDDGVQNGSHEDDDAHCDDGVQNGSHEDDDDNFYDSHHNDPFRINKTPIWGGNVIRNFRGALKDNDHGVHGGGTYGMGNSPEAALKKASGRNKGGELKHLMDLSPFRRTSQLEMGETIDLVDLSPLGNMPLRNACGRNEECELKQLDFLSPLSHKTSPLEMGATINLTPLSCTISSCTKQSSRIAGSLHPEIIDLTDSPLIIQL
The following text describes a protein:
Function:
Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
Sequence:
MLNPPLNQLTSQIKSKYLIATTAAKRAREIDEQPETELLSEYHSFKPVGRALEEIADGKIRPVISSDYYGKE