lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Cell surface receptor that plays a functionally redundant role in the inhibition of neurite outgrowth mediated by MAG. Plays a functionally redundant role in postnatal brain development. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Does not seem to play a significant role in regulating axon regeneration in the adult central nervous system (By similarity). Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG. Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development. Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor. Cell projection, dendrite. Perikaryon. Cell projection, axon. Membrane raft. Note=Localized to the surface of neurons, including axons. Detected close to synapses, but is excluded from synapses (By similarity).
Sequence:
MLPGLRRLLQGPASACLLLTLLALPPVTPSCPMLCTCYSSPPTVSCQANNFSSVPLSLPPSTQRLFLQNNLIRSLRPGTFGPNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFHGLSRLTILYLFNNSLASLPGEALADLPALEFLRLNANPWACDCRARPLWAWFQRARVSSSDVTCATPPERQGRDLRTLRDTDFQACPPPTPTRPGSRARGNSSSNHLYGVAEAGAPPADPSTLYRDLPAEDSRGRQGGDAPTEDDYWGGYGGEDQRGEQTCPGAACQAPADSRGPVLSAGLRTPLLCLLLLAPHHL
The following text describes a protein:
Function:
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes, on the cytoplasmic face of the endoplasmic reticulum, the addition of the fourth and fifth mannose residues to the dolichol-linked oligosaccharide chain, to produce Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MDSLILQLTYAALSAFLLTFILIVTQCRHTFQQIREAFVLYQRQCNVDAAASSNGSSSADGSSNNNNSNKKRGSKGLNQKKGSKSAATTNEEFNQDEGTFTIGIFHPNCSSGGGGERVLWKAIEALGEMKEGKIPTRRGKMRRDDSDLLKHVCDRFAITIPSSLSINFVHLHEEKYLLNKSKRLTMVAESLGTMRLAWHALNKVTPHVFIDTTGCAFTFFVAKVLAGCKVGTYIHYPTISTDMLSLVWERRPTYNNTSRIATNPIVTYVKLIYYTIFAVCYGLVGSLADLTMVNSTWTKGHIQYLWRLAGRVHVVFPPVDTKSVKELPISNPPRENLIVSIGQFRPEKDHSLQLKAFASLLEMYDGAMEQSNVKLVLIGSCRGEDDQQRVDQLQKLARELGVQDSVEFVLNQPYPVLRDYLRRASVGIHTMWNEHFGIGVVEMMAAGLVTVAHDSGGPKSDIIVRPCDFKSVNLTSATTATTGSNSPTGCLASTVEEYATAMYEILKRGALSEETLAIRESGRIAAERFSDDVFMSSFKETMISSTLFK
The following text describes a protein:
Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MLFAQLVILVIIVMLFLCRFANKLRGLPPGPTPWPFIGNTFQVPEDRIDLIINEFKKKYGGIFTLWLPFPTIVICDYDMLKRNIVKNGESFSGRPDTFIMDMLVQGNYGLFFMENNWWKAQRRFTTHIFRSLGVGQAGTQDTIASLASGLVEKIDGQKDKPIELRPLLVHVVGNVIHKHLFGFTREWNETEILDFHVAINDVLEHFTSPKTQLLDAWPWLAYLDKPLSLGIPRTTRANDAIIQNLEQALAKHKTGINYDEEPSSYMDAFLKEMKIRAAENALEDGFTEKQLIVAIYDLYSAGMETIIIVLRFAFLYLVNNPETQKRIHEELDRNVGRERQVVMDDQKHLPYTCAFLQEVYRLGYVLPVNFLRCTLTDVEDCEGYRLNAGTRVIAQFQSVHVDKKHFPDPEHFNPDRFLNSRGEYIRDDRVNPFSMGKRSCLGENLARMEVFLYFCTLMQNFEWHTDGPYAPPIDVITSSLRAPKPFTVRASRR
The following text describes a protein:
Function:
Cell surface protein involved in the ability to sense and respond to changes in the host environment. Required for stress response and confers partial antifungal drug resistance. Contributes to the DNA damage response. Required for the flocculation response stimulated by 3-aminotriazole-induced amino acid starvation.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MVFGFGKDDDKDKNDRRDNDSYGSSNRRNNDDSYGSSSFGSSNDDDNSYGSSNKRSNDSYGSSNTDSYGSSNRRDNDSYGSSNNDSYGSSKTDSYGSSNRSGNDSYGSSNNDSYGSSNRKGNDSYGSSNTDSYGSSNTDSYGSSNTDSYGSSNKRGNDSYGSSNDDSYGSSNDDSYGSSNRRGNDSYGSSNDDSYGSSNRRGNSDSYGSSDY
The following text describes a protein:
Function:
Appears to have a multifaceted role in controlling cell morphology, completion of cell division and separation, as well as chromosome segregation, through a complex interaction web. Seems to be primarily involved in the formation and maturation of the cell poles.
Subcellular Localization:
Cytoplasm. Note=Localizes primarily near the membrane at the midcell division sites (as a ring) and at the cell poles (as dots) simultaneously. DivIVA is recruited to the septum at a later stage than FtsZ and is retained at the poles after cell separation.
Sequence:
MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANHDKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQRLLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWEDILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEVADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK
The following text describes a protein:
Function:
Forms chloride channels.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane.
Sequence:
SKNYSYCYLNYIGDATILLYLQIKLGGLAGLLLRWRASVYKLLWREMIVFILFYTVVSLIYRFALVGSDDVKIGFEKLAIYAYDYTKVFPISFVLGFYVTVVFDRWWMQFKSIPWPDRVVYNVSAHVLGNDEDGKIIRRTLARYVNLAAILVYRSGSKRVKKRFPTLAHLVEAGLMTDDEKDIFKNLGTENPKYWVPCAWFVNLCRMCRKQARIISDPAMKTVVDELNNFQNKCFELYGYDWIVVPLVYTQVVTIATYSYFLACLFGRQYLDPLMGYDGHTIDVYVPGFTILEFVFYVGWLKVAENLMNPFGEDDDDFDMNWIVDRNIETSFMVVDELYEVSLPIVRDRHFSTRHPDIPYTNAAAKQKGKPWLGSASKVKLSRQQMAFTNMPNKVFTEDDEVITSSLNKKRGETPGKTGTNNGSLSKVSKSGGGNGHASSSNNHGLEEKRSRSRSSSRNEGSTPRVIHRTLSHEDSQYDHYASIPNTPQIPQADYEAVTRRGQSATRGSNHGNKYSGEPEVHRRLSKSTEERKRLASDRQQGRLRNNQSLEREGNYSSGHERAGSSAGSGSGGGGGGGKNIGGGGDGGNYHRSSSQERGGNYHSTHERNSNYHNGYHYDDYQGPGSSDGRQVPDDVKECRDRDVDGVIDARDVDINALNESII
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MAGTFSGYVHKLPSLVIDLDNTLIFSTELPTRQHEFECDVGRKKYFVHVRPGTYEFLEKISKYYEIFFFTVSRREYSESIIRHIAPYVKKENCLYRDSCLFAQGYAIKDLNKIDRPLKQVVLVDDSLGTALAFPVNTIGVEPWEGNNQDRVLIKELFPLLLSAAGETDVPLAIRNSVIDVKPQHLYFK
The following text describes a protein:
Function:
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
Sequence:
MGGNVMTDDKMNSVTSGANKQETGRDMSNRDWWPNHLKLEILHQHSSKSNPMGEDFNYAKEFKSLDLAAVKKDLAALMTDSQDWWPADFGHYGPLFIRMAWHSAGTYRAGDGRGGGGRGQQRFAPLNSWPDNVNLDKARRLLWPIKQKYGRKISWADLMILTGNVAMETMGFKTFGFGGGREDVWEPDQDVYWGSEDTWLGDERYTGDRDLENPLAAVQMGLIYVNPEGPNGNPDPIAAAKDIREVFARMAMNDEETVALIAGGHAFGKTHGAGPASHVGPEPEAASIEAQGLGWKSSFGTGKGDDTITGGLEVTWTNTPTKWSNNFFRILFGYEWELTKSPAGAYQWKPKGGAGAGTIPDAHDPSKRHAPSMMTTDLSLRFDPVYEKISRHFYENPGQLADSFARAWFKLTHRDMGPRARYLGPEVPAEELIWQDPIPAVNHELIDEKDIAFLKDRILASGLSISQLVSTAWVSASTFRGSDKRGGANGARIRLAPQKDWEVNQPAELAKVLNTLEGIQSEFNSAASGGKKVSLADLIVLAGCAGVEQAAKNAGYDVTVPFLPGRMDALQEQTDVVSFALLEPIADGFRNYLKAQYPLPAEELLVDKAQLLTLTAPEMTVLVGGMRVLNTNFGHTQHGVFTQKPEALTNDFFVNLLDMGTEWKAVSDVKDIFEGCDRKTGEVKWTGTRVDLIFGSNSQLRALAEVYGSADAQEKFVQDFVAAWTKVMNLDRFDLA
The following text describes a protein:
Function:
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MLPSGTTMEEGTQKKKKKPLVPPSPRPPRSLFCLGLQNPFRKSCINIVEWKPFEMIILLTIFANCIALAIYLPMPEDDTNSVNTILEKIEYIFLFIFTIEAALKIVAYGFILHSDAYLRNCWNILDFTIVSVGLFTIVLEQINKVQGVTAPGGTGFNVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFMIIIYAIVGKELFSGKMHKTCYYKATDVIATVEKPSPCSTTGQGRQCAINGSECRGWWPGPNNGITHFDNFGFAMLTVYQCITMEGWTEVLYWVNDAIGNEWPWIYFVSLILLGSFFVLNLVLGVLSGEFTKEREKAKSRGAFQKLREQQAMDEDLRGYLDWITHAEVMDPDMEQGDGFSQLEEGCSETESLYELEGINKFISFLKQWRHWHRLLRRKCRDLVKSRFFYWFVILIILFNTITIATEHHNQPEWLTKAQDIANQVLLAMFTLEMVLKIYALGFQSYFMSLFNRFDCFVVCTGILEILLVSSNIMSPLGISVLRCIRLLRIFKITRYWTSLNNLVASLLNSVRSIASLLLLLFLFMIIFALLGMQMFGGKFDFEDTEIRRSTFDNFPQSLITVFQILTGEDWNSVMYNGIMAYGGPTFPGMFVCIYFIILFVCGNYILLNVFLAIAVDNLAEAENLTSAQKAKAEERKRKKLARAHPDKSEEEKLLLAKKLEMKAKGEGIPTTAKLKIDEFESNVNEIKDPYPSADFPGDDEEEEPEIPISPRPRPLAELQLKEKAVPMPDASSFFIFGPTNKFRVLCHRIVNATTFTNFILLFILLSSISLAAEDPIEPESFRNQILAYFDYVFTAIFTTEIALKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIKTIGNIVLVTTLLQFMFSCIGVQLFKGKFYSCTDTTKMTEEECRGYFIVAKDGDSTQIQLRERIWTHSDFHFDNVLSGMMSLFTISTFEGWPQLLYRAIDSHSEDMGPIYNYRIEIAVFFIIYIILIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVQYALKARPLRRYIPKNQHQYKIWYLVTSSYFEYLMFALIMLNTISLGMQHYGQTAEFSHLSDILNVAFTGIFTVEMVLKLAAFKAKGYFGDPWNVFDFLIVIGSIIDVILSEIDTPEPVVTPGSEDTSRISITFFRLFRVMRLVKLLSRGEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIAMVDGTQINRNNNFQTFPQAVLVLFRCATGEAWQEILLACSYGKLCDPKSDFLPGEEYTCGTSFAYFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVSMNMPLNSDGTVTFNATLFSLVRTALKIKTEGNFEQSNEELRMIIKKIWKRTSMKLLDQVIPPIGDDEVTVGKFYAIFLIQEHFRKFKKRQEEYYGYRPKKNNVEIQAGLRTVEEEVEPEMQRAISGDLTAEEELERAMVEAAIEEGIYRRTGGLFGQEENFPEPVSPVHTTITSQRPLRFSEAGSEDLESPVFLPDPVFFPPPRRNRNTNNSTLSRGLGERLTTPEEDLKQNISEQWDASTNASQEDLSDHFSL
The following text describes a protein:
Function:
Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of the bicoumarin kotanin. The non-reducing polyketide synthase ktnS first catalyzes the formation of the pentaketidic 4,7-dihydroxy-5-methylcoumarin from acetyl coenzyme A and 4 malonyl coenzyme A molecules. Further O-methylation by ktnB leads to the formation of 7-demethylsiderin. Then, an oxidative phenol coupling catalyzed by the cytochrome P450 monooxygenase ktnC forms the 8,8'-dimer P-orlandin via dimerization the monomeric precursor, 7-demethylsiderin. P-orlandin is subsequently O-methylated in a stepwise fashion to demethylkotanin and kotanin.
Sequence:
MTYPEEIDEYSLIQNGLKSLNEAAQRCQQTKHSSQDSSIEGCSARQSARDELVLEALKFLQIAQGPIDAAATCYERTAHLASVRALLEMGVFEALPTGRVSRRTEELARELNVDESLLARLLRNSSLYGPFEETGPGQYRHTPFSEAYLRPEIRGMFRFAMDDHMPAHLKLHEFLQRNGWQEPSSTTDNPYTYAHKTNGKSMFDNLSEKPERMKAFNNGMTVQAMTPLWMIDLFPWRSLAQLKPTAGQVLAVDIGGGKGKAISRIRSFCNGLPGRYILQDQEHVVKSVEGSLDPSIERMAYNFFTEQPIRGAVTYLIRRCLHNWPQDSVVCILQNIAAAMEPGKSRLLIEEIVVPAEKAGVEEGWMDMIMMSLGAKQRTLKEWEMVLGLAGLEVKKVYQIPGNCHGLIEAWLK
The following text describes a protein:
Function:
As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.
Subcellular Localization:
Lysosome.
Sequence:
MDVNPLAVILVENGSKGDRLLFRYPYDTQATPNFAKRTRAKQLQTPYPQISAEDMQKTSAAYSSTISGSVHSFPSKVLSNLFAVKSELCGKKFEIKINDIRFVGHPLLVYHQGEGKSAGSSQESILSFNVVFALKASASHAVVDCYHEVSKRIAAALWHEERRVAYLSEEAKVMTSTQDDISSELPDDPLDVPYHLILQRSQLARDLRRVYEDLQISGKIHLRINRWILISCCLPQKIYHLLDPGLIIEPADIHACMEALRPYHAILLLGDKEKIINNLPLDSSPALKRLINLANPLKSLQTLAADADLTLSHVFQLVGHMLYFGHATIIYPLCDSNVYVLAGSANTSPQSKLADVFSEMFNSACLIQIMSEFSVPVSLSQRRNPLATPEQESEEIKIIIWMLQHHLLIQLHTYVHIVTRVTFASRQSTPDDLNAGSSLTRMPSDSDMASVISDEALSSPPSHKSISSKAPLCKYFRGKHHLEEIMYLENVRRSDLLHLIDKFRTILITFEHEDSACSVFYKNSTT
The following text describes a protein:
Function:
Converts GTP to 7,8-dihydroneopterin triphosphate.
Sequence:
MNALTLPDIARQTTTADLPLDWVGMQGIALPVQIGGQRVAAEADAGVSLDDPQARGIHMSRLYLALAELEQGELDLSCLRAVLQRFLDSHAGLSRRAYLRLRLAPLLRRPALVSPLSGWKRYPLVLDTRLEGDDFQAEVHLELTYSSTCPCSAALARQLIQERFDQDFAGQPLDHASVLAWLGSSAGIVATPHSQRSSAHLRIGLAEDCIGLPLEELADLGESALGTAVQTAVKRADEQAFALANGQNLMFCEDAVRRLHRALQGYPQASRFSIRVVHAESLHAHDAVAESHWQRGAA
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates ribosomal protein S18 (RPS18A and RPS18B) at 'Lys-48' and dimethylates ribosomal protein L23 (RPL23A and RPL23B) at 'Lys-106' and 'Lys-110'.
Miscellaneous:
MISCELLANEOUS: Present with 4800 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSSDALKALLQWGASFGVIVPEELKFLYTDLKGIICVCEKDIDNPSIKIPPEIVISRNLPMKFFGLSESTKNINGWLKLFFAKIKFDRDNDTIVDNVRVNDKFKPYLDALPSRLNSPLVWNPSELKRLSSTNIGNSIHEKFEGIFKEWFELVSSSDMFDLERVADDVQTFHNLDELTYEALYEKILKITELQRPTIWYSFPAFLWSHLIFISRAFPEYVLNRNCPDNSIVLLPIVDLLNHDYRSKVKWYPENGWFCYEKIGTASQSRELSNNYGGKGNEELLSGYGFVLEDNIFDSVALKVKLPLDVVSTILETEPSLKLPLLSDYTTYAFENKDCVQQEKKATRSATDYINGVTYFINIQNEQCLEPLLDLFTYLSKAEEEDLHDLRARLQGIQMLRNALQSKLNSITGPPATDDSYAIDPYRVYCADVYTKGQKQILKEALTRLKKLEKTMLSENKHQLLTMSKILKNDPAFAETELPSLFSNEDGEEVIFESTYDLLILWILLKTKKNSYPTKYEWVGQQYTNFKQTAYISDDAKAFHTAYFEKQDDVDLAEVDHAIQFVVDNSFTRTSSTTEETILVRK
The following text describes a protein:
Function:
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
Subcellular Localization:
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane.
Sequence:
MADRKKRDRYAGAAYEFGANSSGQAGAGGPPPAPGYGAPAAPGYGAPGAPGYGAPVTPGYGAPQPAYGAPAPAYGQPPAQDPNALGQQFGQMNLGPQQGQAAPQVQQPNAATQQNQLFPSDLIAQPFHVSELYNPPPPINLPSNAAATPSEFANESSKYLRCTLNTIPTNHSLLKKSKLPFALVISPYASLHDSEDQVPVVHDQIISRCRRCRAYINPFVSFLDHGHRWRCNMCNLTNDVPQAFDWDAAQQKSVDRWQRPELNYAVTEFVAPQEYMVRPPQPLCYYIILDCTQAAVNCGLLAVVSRVIKESLGRIPNADGRTRIGFMAVDSGLHFFSIPADNSENNDPQQLVVSDLEEPYLPMPSDLLVSLSQCRTNIESFLDRLPGMFQNTHVPGFALGSALRSAHKLISPLGGKLTVIGASLPNVGHAALTPREDKSLLGTGKETGLLQPANNWYKSFAVECSKNQVSVDMFLFSSQYQDVATLSNLPRFTAGQTYFYPGWNAARLRLSWADYLSAEIGLEAVLRVRATTGLRMSAFYGNFFNRSSDLCAFPAYPRDQTVVIEVAIDETISKPFACLQAAVLHTTSSGQRRIRVLTLAVPTTENLASVYASADAQAITTYFSHKAVERALSSGLDAARDALQGKIIEILQTYRKELAGGSMGGGGLQLPQNLRALPLLFLGLIKNVGLRKSSQIPSDLRSAALDLLSTLPLRLLTQYIYPSFYSLHVFPALLADVFGVEDRTQLKQGKFTLPVLDNEYSERVRAVVEKSRDHKAKGVGSILLPQLYAIKEDGDPMLKLWAQTLLVEDRADQGESIVQWISKLREKVCPDLQDVPLIPSTWPE
The following text describes a protein:
Function:
Involved in biosynthesis of the polyprenyl side-chain of methanophenazine, an electron carrier utilized for methanogenesis. Catalyzes the condensation of isopentenyl pyrophosphate with the allylic pyrophosphates to yield geranylfarnesyl diphosphate (GFPP). It prefers geranylgeranyl diphosphate (GGPP) and farnesyl diphosphate (FPP) as allylic substrate.
Sequence:
MPVKVHGVILMNIEEWEEYRYVEAGIKESITLIEDPGLKKMVEHVCHSGGKRIRPIILLLVSEICSGSYSRSLNAALAVEMMHSASLIHDDLLDQGLVRRNLPSAPEKFGPSGALLCGDYLIAKSIAFISPYGEKVIQDFGKAGMDMAEGEVLDLKLEDESFGENDYFKCIYKKTASLFAISASIGAYTGGAEEELAERFSHFGNALGTAYQIVDDILEFLEVVEGKESKFTSETLPHIYMKSTSKEEALKKSIDCVKLHVAAAKETLETFRECPARDKLFQITDYITVDMLENL
The following text describes a protein:
Function:
Required for normal mitochondrial ribosome function and mitochondrial translation. May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits. Interacts with mitochondrial ribosomal protein uL14m (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome. May function as a ribosomal silencing factor.
Subcellular Localization:
Mitochondrion.
Sequence:
MWRALLGGCRLLRSRSAAPVVGAPRAGGSAAVRNAGGGGAAAAAPEWRQATDASLPKFNIDFVVNLLRQENAKDICVIQVPPEIKYCHYFIVVSGSSTRHLHAMAQYMLKMYKHQKEESDPHTRIEGKETHDWLCIDFGSIVVHFMLPETRETYELEKLWTLGSYDDQLAQMTPQLLPEDFILGLTSEEQ
The following text describes a protein:
Function:
Probably involved in the defense reaction of plants against pathogens.
Sequence:
MAFKLVNLLVLFIIQVLPLTMASSSSFSSSSSSSSSTATKISSTGSVFRERDPNNPNSTTEISKSVIKTKMCYNSHCFFRVRIRYPSRNKENQNENRVEDEKISRSRREKYKNAINHMPMPKEILNVKKSHHMYERHIKEEFLDAHNYARTFFKEKPFQWNKSLAKKAQKWAAKLSVPCKYIEHSDTPYGENIFLGRGRRWRATDAVQEWANERSAYNAENYRCFDNQICGHFTQIIWRSTHEIGCARKWCKSKRGVIIVCNYDPPGNYIGENPFEN
The following text describes a protein:
Function:
Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase. RAD9A possesses 3'->5' double stranded DNA exonuclease activity.
Subcellular Localization:
Nucleus.
Sequence:
MKCVIEGNGIKVFGRAIHALSRIGDEIWLDPLEDGLAVRTVNSSQSGYACFCFAPLFFQQYIPDPATKDSQAVKCKLNLKCVLPMFRCVTCRERSVDRCEISIKIPDGRVTFRFHCRHGITKTHNLGYQECEALQAVFPAHLSPNVLMAQSKLLGGIVVHFPVSQEEVTLSVSSLKVVLKTFCVEENDCIKGMNTALMLHPDELDYFQVGEDSDVTFCLKELRGLLSFAECYGLPVSCQFGAAGQPISFTVKDITLEAHVVLSTLTNPDSESSSQPAPRDDCPVKTPKASTAENSTYEEPMEAEVCVSDGERVASSQGSEMFSPARHMRKMMQLHAPEEILQRPCFAPESVLTTPVTPATFKIRSLLFGAVYNSGDGKAADFPSLVYASDTEDDGGTQETIR
The following text describes a protein:
Function:
ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
Subcellular Localization:
Nucleus.
Sequence:
MSDLDDYFDDDIDAAAFDAVLSAATSVPPPTRQPVVVPTTRQPASITRQPASTTRQPASTTRQSGPKDRQPALNIRHPTPPPVNREPIAASSSTIDDCFDDDIDAAAFDAVVNAATSAQPTTRQALGGSGLTQKKYTQTTIFGASQVPAKPSRPSKQPTSSQYQPPVPKATQQEPKVKAVKKWDNLRAIKDVLPDINQKGKKRKKSKFADDDDEEEEMMDDEEVDSDTDLLNQALQETNHKKVPMKLQSDSEAIKTWIYSINKPKRKYQYDIVARALYNNCLVSLPTGLGKTFIAAVVMLNFYRWYPRGKVIFLAPTRPLVQQQIEACHSIAGIPSVDCVSLTGTTSATKRAVAWENKRVIFATPQTVANDLRRGSLRPEDIICLVVDEAHRATGAYAYCIVVKLLMRFNPHFRVLALTATPGSDPERVQAVIDNLHIGHIEVRTEESMDIVPYTKNKEIVLEKIPLTPELTSIRDKWGKLMLPLIKQCGALFHGSKEPAYIHAFSITSAQMHIPKEKSYLRPNLAVLSKMATAMAKLLEYSITLAYEKMQELKEESGKCAAGVCSQVGYKSLMTEIRDLTQSPDFVPHPKMEKMKALTLEFFINAQDQGKSSRVMIFCHFRDMVTDIVNYLNQEKPIIKASAFVGQSNDVRGNRGMNQKTQNETIQRFKNNEFNVLVATSIGEEGLDIGALDFIICYEAQKSPLRMLQRLGRTGRNEDGKVIVLIAEGREDKNWEKAQDQYQHVQNALLSKKVLELYEDCERLVPEGVRPTAVDKEIDVQPYIADQVELAVSPSGRKKKDKPTKRKRPGAEDIPAGGIFGFVSAKDYAVPKSKADSLRQRTEAALLTAEEAAILKQQWSKNITVAPSPIDPENLKIEYFPTKSALGSRLESVPQNKRSARNITRSAKYTRIMNQCDSYVHDDAKYEAWREDTIARLESKNVTWWPPELRGMGAQKPLRLCSDGPKSIRRRWTNSKDAGASTPVPQPRSPTIAAFSSPRSSSPRLLDEFGEGAPRAISPKGKSKKASQLDEPPSSHDDLPDFEDFIPSMKTSERLLPPPSIASPSPLASTSANAPPHARPDSTRPGQSSSFQRLAAFKSSVSEPAPFQEAVPFRQEFPNNAPVTPSGPSNDRGVTKKRLVGPARFQDDDDHSPLLFRALTHNNKQAPPISPSEYENGDDFLRPEILPNTQMPRSKRIQKSVGFGGKQKRIIAPESDDDDDDHKDDDGDVMVGEDGPDGPQSHKKSERKSDRHVKTRKDGASSSKGKGKQRQQKSSHSTRGNEWALKTGLFDLEASESDTSSSSEEEGEEGGSGDGQRKKKKRRKKGKGGRKKKKRSSSEEIESENSIDRDFLVNTSSSKIQDDCSPDKSMTSFYRASILMMSQPLSVVKTKLGKRAPSPQPRPNNHPLHHHHRSNPPRQSSSRRPISSEHDHPDDRFSFDSFCVPDEETIEYEDEDCHGIPSDL
The following text describes a protein:
Function:
Probable lipase.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MHLPFPVLRRLYLYEYTALVLGFALVVFESFVASLAFVINSLVVKVFPKWSVWNKKTALQAYAVDDIETIDKAFSLHDAKSIREMCEVHGFGVEEHLIRTNDDYILCVHRIYQMTDNALNGPGKPKSRPVVYCHHGLLMNSEVWVCNLDANKCLVFDLVRRGYDVWLGNNRGNKYSRQHLYLRSSDVDFWDFCIDDFAQYDIPDTIHYILNVTEQPSLSYVGFSQGTAQAFASLSIHPLLNEKVNTFIALAPAISPRGLHSSVGDAIVRANPFLLYMFFGHKSFLASAGFWQSILYPPLFDVVLNYCLVHLFDWRCKNMTPLQKLVSYAHLYSYTSVKCLVHWFQIMHSGEFRMYDNDMLIQSTYAPYYKAARFPTKNIRTPIHLLWGDCDSLVDINVMLNVLPEGTQEVRVDSYEHLDMIWSDTVDVDVNPHVFQWLEQAKRG
The following text describes a protein:
Function:
Cell autonomous antagonist of the canonical Wnt signaling pathway.
Subcellular Localization:
Cell membrane. Cytoplasm.
Sequence:
MDVISFTTWFVFTTQRVALSPSVRSYPLGDAKNTAKNAACVDSFVGSQTRNYTQGYWKLEALESSWNRIIYVLRIEISKESEKWEQNKEKCENLCLANSDLVVDKARIEYRSALLPPSAARTGGKTPNKPEHQTTMKKLHRKLKQKSRDGSESDRAWISREGPEGDCVIENDTTTHSCAVSTSAYEELSRAPSSHTADFTYKGYPVNLVIFDWGSLWRVKHGLRIRFLGLPEWPLDYEEKELPSKKDFFYDDFPLEVVELPDLPDGKNVEISFEREGLVEASTQTKPLKQETPECGMSVKSASSDHQEWSYTLYDFEGQGQVTREDLRNLVKSIYEVLGKSVNNSRNQPKDPLKKLRVRLSVSKERGKGTEGDVPSRHEYTISAMATENKAPKKSTRTYHMERCDSMTVNPPSLENIPDKRKMVSLIMEQPGPTNGINCQSHRQKISCKRSSANRPAKPAVTAANTGNMDTPVVNDRGMYSCPKRMQTGPGECNPPSPKEANDLSRVKQWVDQLCAAHELETVTRSKHRKSYRHTCRQGEPRHDLHRCPQYLDLATDHITYPYHVESQACLFGAASPKPHRRPKRGHHHSCKYNKDEVMCQRTIVHRHEHHHSHHHYHHYEKQEPSNK
The following text describes a protein:
Function:
Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MNELRRRWQIMSQRERMMTLACGGLVLLCLLYYLCWAPWQERARQWQMTIDRERQTVRWMQQQAPRLPPAEGARRQIAGRDISLTVLVPQSAARYGITVLRMQPQESQVSVTLARSDFNNLLHWLAELEQKNGVITQGLDVTAVPNSAGMVEVTRLSLERVL
The following text describes a protein:
Function:
May be involved in cooperative interactions with calmodulins or calmodulin-like proteins (By similarity). Recruits calmodulin proteins to microtubules, thus being a potential scaffold in cellular signaling and trafficking (By similarity). May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level (By similarity).
Subcellular Localization:
Nucleus. Nucleus, nucleolus. Cytoplasm, cytoskeleton. Cell membrane.
Sequence:
MGFFGRLFGSKKKSDKAASSRDKRRWSFTTRSSNSSKRAPAVTSASVVEQNGLDADKHAIAVAAATAAVAEAALTAAHAAAEVVRLTSGNGGRNVGGGGNSSVFQIGRSNRRWAQENIAAMKIQSAFRGYLARRALRALKALVKLQALVRGHIVRKQTADMLRRMQTLVRLQSQARARASRSSHSSASFHSSTALLFPSSSSSPRSLHTRCVSNAEVSSLDHRGGSKRLDWQAEESENGDKILEVDTWKPHYHPKPLRSERNNESPRKRQQSLLGPRSTENSPQVGSSGSRRRTPFTPTSRSEYSWGCNNYYYSGYHPNYMANTESYKAKVRSQSAPKQRVEVSNETSGYKRSVQGQYYYYTAVEEESLDVGSAGYYGGGGGDSDRLNRNQSAKSRMHSSFLV
The following text describes a protein:
Function:
Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.
Subcellular Localization:
Nucleus.
Sequence:
MEVHEEQVSAPVTGDATAKYLLQYILSARGICHENALILALMRLETDASTLNTEWSIQQWVDKLNDYINAINVKLNLLGYKIIRINHGIGRNAVTLKAKQNFESFEDNTAIRAHNNDYAVLQSIVLPESNRFFVYVNLASTEETKLATRFNQNEIEFMKWAIEQFMISGETIVEGPALETSIIVKEVNRILVAATGDSNLAKWRKFSTFTVGSTNLFQFQELTATDIEDLLLRLCELKWFYRTQEGKFGIDLRCIAELEEYLTSMYNLNTCQNCHKLAIQGVRCGNESCREENEETGENSLSQIWHVDCFKHYITHVSKNCDRCGSSLITEGVYVI