lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
Subcellular Localization:
Vacuole membrane; Single-pass type II membrane protein. Note=Lysosome-like vacuoles.
Sequence:
MPSTYSDDNTLRSGLDRFRDHSPSQHRRSMSQETDSTVSTTSIVFDRIQERLDTKEFPARGTDGDDNDSLKDELNNDDLETGPFLGNASPSSRSNQRSSADGQRMDRSLRRWLFIVSGALVATWVIGLIFFVSSKAYKPSSSFAHDPQATVTHGSGKKVTLDQVLNNEWRAKSHSISWIAGVNGEDGLLLEKEGANKDYLVVEDVRAQNPSSVEASKSKTLIKDKLFEFANKTYWPTVTVPSRDLKKVLLATDVQNNWRHSYYAVYWIFDVETQQAEPLVPYDADARLQLASWSPTSDAIVYTRDNNMFLRKLDSDKIVQITRDGSADVFNGVPDWVYEEEVLASGVATWWSEDGNYVAFLRTNETGVPEYPIQYFVSRPSGEEPKPGEENYPEVRQIKYPKAGAHNPIVDLKFYDVKRGDVFSVDISGRFADDDRLITEVIWAGKQVLIKETNRVSDVMRVVLVDVGSRTGKAVRTVDVNDIDGGWFEISHKTKFIPADPANGRPDDGYVDTIIHNNGDHLAYFTPLDNPNPIMLTSGDYEVVDAPSAVDLQRNLVYFVSTKESSIQRHVYQVKLTGEDMTPVTDTSKEGYYAISFSTGAGYALVSYQGPNIPWQKVISTPSNPDKYEHVVEENKDLAEAAKKHELPINIYGTINVDGVELNYIERRPPHFDKNKKYPVLFQQYSGPVSQTVKKTFAVDFQSFVAAGLGYICVTVDGRGTGFIGRKNRVIIRGNLGTWESHDQIAAAKHWAQKDYIDEDRLAIWGWSYGGYMTLKTLEQDAGQTFKYGMAVAPVTDWRFYDSIYTERYMRTPQTNPEGYESAAVTNVTALSQNVRFLLMHGVADDNVHMQNSLTLLDALDQRSVENYDVQVFPDSDHGIYFHNANRIVFDKLTNWLVNAFNGEWLKIANAQPNGMKRRALPTA
The following text describes a protein:
Function:
Methyltransferase which catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine).
Sequence:
MSSDELLQAQLELYHHGLAFVKSLALKAATDLRIPDAIHRRGGAATLSELASDTGIHPTKRSNLRRVMRVLTTTGVFSIVQGKGSNDHAGDGAAYYKLTRVSRLLVERSPHNLSPMHSLVQLANGCTFWDTTKVDGGLFNDGMAADSRIAMKVLLKEHGGAFREVKSSLVDIGGNHGATASAVARAFPHLKCSVLDLPHVVAAAPASDILTFVAGNMFEYVPPADAVLLKWILHDWKHEDCVKIMRRCKEAIPAKEAGGKVIIIDMVVGYPVTQPNHSKEAQVLLDIYMMGSDGMEREENEWSLIFSEAGFSDYKITRTNGIRSIIEVYP
The following text describes a protein:
Function:
Probable lipase.
Sequence:
MSLCERAASGSALLWPRVLLFGDSITQFSFQQGGWGSLLADRLVRKCDVLNRGFSGYNTRWAKIILPRLIRKGPGMENPVAVTIFFGANDSSLKDENPKQHVPLDEYSANLRDMVQYLRSVDVPRERVILITPPPLCEAAWEKECVLKGCKLNRLNSVVGEYANACLQVARDCGTDVLDLWTLMQKDSQDFSSYLSDGLHLSPMGNEFLFLNLCPLLDKKVSSLPWLLPYWKDVEEAKPELSLLGDGDY
The following text describes a protein:
Function:
Interacts with target proteins during translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation and facilitate correct glycosylation.
Subcellular Localization:
Membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MPTFKDIRAKNAQFAASARENAGKARVRTSKDAPDSVEAKQSQQQGGRNIVKRARSDRRAQNKSAGLSNNKLALGLIVFVVCGGVFFELIRLFL
The following text describes a protein:
Function:
Deubiquitinating enzyme that hydrolyzes 'Lys-6'- and 'Lys-11'-linked polyubiquitin. Also hydrolyzes heterotypic (mixed and branched) and homotypic chains. Important regulator of energy metabolism. Glucose and fatty acids trigger its nuclear translocation by CBP-dependent acetylation. In the nucleus, deubiquitinates and stabilizes the nuclear receptor PPARD regulating the expression of various genes involved in glucose and lipid metabolism and oxidative phosphorylation. Also acts as a negative regulator of the ribosome quality control (RQC) by mediating deubiquitination of 40S ribosomal proteins RPS10/eS10 and RPS20/uS10, thereby antagonizing ZNF598-mediated 40S ubiquitination.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MARSAAQNQERQGQRSAQQGGQSKPSKGQRQDAAERKRDERAIRNAYRKTKKDESYLADDQNFASFATQLQSMGLQLRDIPGDGNCLFRALGDQLEGHGRNHMAHRLDVVQYMRDHKDNFEPFMEDDVPFERHLVNLAKPGTYAGNDSIVAFARLLKVNVVIHQLNLPVWRIVGSDKPSCKELHISYHNGDHYSSVRKLGDNSEKATNFRNGGESSSSDIKPKPKARTKSKVSDEIDPPYTNGTVEEDGLIDVELHIMVETGCEDVQLIRETFMDNECNVDATIGVLLQVTNADCDTFSHDNNSIKSGERSPQGAAGIWSTDGSGTRLFGVPEDSDSSSSSKTQPNRTPGGKAKNQSTRQQKAQKRLEKKQRQAERHRQRIQGENCHSNTTTSSDEESSSVVLVGQMGALSI
The following text describes a protein:
Function:
Aldo-keto reductase; part of the gene cluster B that mediates the biosynthesis of austinol and dehydroaustinol, two fungal meroterpenoids. The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid by the polyketide synthase ausA. 3,5-dimethylorsellinic acid is then prenylated by the polyprenyl transferase ausN. Further epoxidation by the FAD-dependent monooxygenase ausM and cyclization by the probable terpene cyclase ausL lead to the formation of protoaustinoid A. Protoaustinoid A is then oxidized to spiro-lactone preaustinoid A3 by the combined action of the FAD-binding monooxygenases ausB and ausC, and the dioxygenase ausE. Acid-catalyzed keto-rearrangement and ring contraction of the tetraketide portion of preaustinoid A3 by ausJ lead to the formation of preaustinoid A4. The aldo-keto reductase ausK, with the help of ausH, is involved in the next step by transforming preaustinoid A4 into isoaustinone which is in turn hydroxylated by the P450 monooxygenase ausI to form austinolide. Finally, the cytochrome P450 monooxygenase ausG modifies austinolide to austinol. Austinol can be further modified to dehydroaustinol which forms a diffusible complex with diorcinol that initiates conidiation. Due to genetic rearrangements of the clusters and the subsequent loss of some enzymes, the end products of the Emericella nidulans austinoid biosynthesis clusters are austinol and dehydroaustinol, even if additional enzymes, such as the O-acetyltransferase ausQ and the cytochrome P450 monooxygenase ausR are still functional.
Miscellaneous:
MISCELLANEOUS: In A.calidoustus, the austinoid gene cluster lies on a contiguous DNA region, while clusters from E.nidulans and P.brasilianum are split in their respective genomes. Genetic rearrangements provoked variability among the clusters and E.nidulans produces the least number of austionoid derivatives with the end products austinol and dehydroaustinol, while P.brasilianum can produce until acetoxydehydroaustin, and A.calidoustus produces the highest number of identified derivatives.
Sequence:
MTGTRILELFGPAPEPPSELGRYRILSPTAGIRVSPLQLGALSIGDAWSTDLGSMDKDSAMELLDAYAAAGGNFIDTANAYQNEQSEMWIGEWMASRGNRDKMVIATKFGTDYRAHELGKGLAVNYSGNHKRSLHMSVRDSLQKLRTSWIDILYLHTWDYTTSIPELMDSLHHLVQRGDVLYLGICNTPAWVVSAANTYAQQQGKTQFSVYQGRWNPLRRELERDILPMARHFGMAVTVYDALGSGKFQSRDMLARRKDQGEGLRAIYGGQQTALEEAMSKALGVVAAQHGIESVTAVALAYLLAKAPYVFPIIGGRKIQHLHDNIEALSLRLSQEEIEYLESVGDFDPGFPYDMAGVDPADTGIATPIVAQAAPMAFVQRSKAIGYAESSKGSQMFG
The following text describes a protein:
Function:
Required for efficient biogenesis of the 60S ribosomal subunit.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MVAAKRKATGASANPRRRRQRKTRTLAVSSEDESSSSASSSSSSSSEDDDESDQDRSSMKSSLRKRPKISEFRPRSNSSSSASSSASSSASSSASVESDSSASTLSTSSSSADSSITDSDSSPHSIGNLSPRSRRKINGPKASAAGSSNNIVESCDKKRHIFRLTPEPEVTESTKICRSTERSSASRMLKSLEPQALRLPTHLQRIVNAKTVPASAREPRTEKRQTTSHEAQHRQDRRQQAFRSLWLKAVADEFGDELDAIRTREPTLGADGGTRLPLFIDALAAGSELFSSSRADNLDAEQTKGTRQASLDELALATCQNTTKK
The following text describes a protein:
Function:
Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor (By similarity). The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm (By similarity). Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix (By similarity).
Subcellular Localization:
Peroxisome membrane; Single-pass membrane protein.
Sequence:
MDNDDINNNNNNNNNNNNNNNSQELDQQEQTQEEITKQRIQKRKEEAKRIMEERKKREQQPPSQRQYEDVEDDQQQQPIRPIKQLPQRQQQYDDNDEPPQQQQYEPKISQRKVPLPPMKQPTTSSTASAATGSILSPSSNFREDMVKKAVLFLNNPNVKNTALARKVAYLEKKGLTSDEVKEALKRVETGNINGSSTNNSNITQSNSISRTRNDNYGNNNNNSSNNNNNIQQQQYYQQQQQQHQQQQQMALTQIQSYQKRLEADDQRIAQLMMNNNRFSWNSFLFSVTAIVGAASGLAYLTSNYIIPFLNGGKTNKDASANMDKKITSLQEEIIKLQSTIIQQGNDFRESTKSLKTLIEQQQQQILQQQQINSVSTTTNSATSASNSSEIVEIKKELKNLINLIGNKENSNNSNNNSNNSNNNNGYSKYNGFNGVYNKSSYDDVSTNNNNKTNSPPSPNKPTTTTTTTATSTPGSNISNTNKTLPPIIKTNPYSHLSWKLPTDQPPVIPSWQQKSSNPPSDLSNANDKSSPSNSNPSTPTKPYQSSFNYGDVNSFVGGSNTLNFDEKPTTTTTTSTTPSNERPSSPSVNNNNNNNNNNNNNNNNNNNNNNNTTIASTSNESNNSKVETTSNDSDKSTSPSSSSNNTTSTTATTTTITSASTEDNKQQSDETPYSSDFLDVINQLKQGKTPPGIRTDIDDKPLENSTVTKSAKERPKKPWERDTLTSVTNNLSVEETQTINNTDSSVEK
The following text describes a protein:
Function:
IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV) and West Nile virus (WNV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation.
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Lysosome membrane.
Sequence:
MPKEQQEVVVLGSPHISTSATATTINMPEISTPDHVVWSLFNTLFMNFCCLGFVAYAYSVKSRDRKMVGDTTGAQAFASTAKCLNISSLFFTILTAIVVIVVCAIR
The following text describes a protein:
Function:
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.
Sequence:
MRASQSPMLDPRARHLLRTLIARYIRDGEPVGSKTLAQHAGLDVSPATIRNILADLEDIGLLSSPHTSAGRVPTAHGYRVFVDSLVQMQPPGEEEVRRLRAELASSNGTQSLLGSASQMLSAMSHFVGVVSAPRREQFAFRHIDFVPLDARRVLAILVFADNEVQNRVIEPRRAYEPAELERVANYLNAQFAGRALSDIRASLLRELRLAKNEMEQLLAHSVDLASEALVPADDDGMVMAGQTRLMGVQDLSDLDRLRELFEAFASKREILQLLERTIQAPGVRIFIGEETGMVSLDDVSLVTAPYTAGGQVLGVLGVIGPKRMAYDRVIPLVQTAAQMLGAAMEPPGTR
The following text describes a protein:
Function:
Required for exine pattern formation during pollen development, especially for primexine deposition.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MKSRARQCLLVCLLCLSLTNLSYGENKFRERKATDDELGYPDIDEDALLNTQCPKKLELRWQTEVTSSVYATPLIADINSDGKLDIVVPSFVHYLEVLEGADGDKMPGWPAFHQSNVHSSPLLFDIDKDGVREIALATYNAEVLFFRVSGFLMSDKLEVPRRKVHKNWHVGLNPDPVDRSHPDVHDDVLEEEAMAMKSSTTQTNATTTTPNVTVSMTKEVHGANSYVSTQEDQKRPENNQTEAIVKPTPELHNSSMDAGANNLAANATTAGSRENLNRNVTTNEVDQSKISGDKNETVIKLNTSTGNSSETLGTSGNSSTAETVTKSGRRLLEEDGSKESVDSHSDSKDNSEGVRMATVENDGGLEADADSSFELLRENDELADEYSYDYDDYVDEKMWGDEEWVEGQHENSEDYVNIDAHILCTPVIADIDKDGVQEMIVAVSYFFDPEYYDNPEHLKELGGIDIKNYIASSIVVFNLDTKQVKWIKELDLSTDKANFRAYIYSSPTVVDLDGDGYLDILVGTSFGLFYAMDHRGNIREKFPLEMAEIQGAVVAADINDDGKIELVTTDSHGNIAAWTTQGVEIWEAHLKSLVPQGPSIGDVDGDGHTEVVVPTSSGNIYVLSGKDGSIVRPYPYRTHGRVMNQLLLVDLNKRGEKKKGLTIVTTSFDGYLYLIDGPTSCTDVVDIGETSYSMVLADNVDGGDDLDLIVSTMNGNVFCFSTPSPHHPLKAWRSSDQGRNNKANRYDREGVFVTHSTRGFRDEEGKNFWAEIEIVDKYRYPSGSQAPYNVTTTLLVPGNYQGERRITQSQIYDRPGKYRIKLPTVGVRTTGTVMVEMADKNGLHFSDEFSLTFHMYYYKLLKWLLVLPMLGMFGLLVILRPQEAVPLPSFSRNTDL
The following text describes a protein:
Function:
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis.
Sequence:
MALPAAPADRRLQPEPDEQLHLNHQDIGELGLPQEPDTEGIPLHSPWTFWLDRSLPGTTAAECESNLKKIYTVHTIQSFWSVYNNIPLVTNLPVRWSYHLMRGERKPLWEEESNAKGGVWKMKVPKEASSLVWKELLLATIGEQFTDRCAPEDEVIGVSVSVRDREDIVQVWNGNASVVAEATVLEKIYELLPNTSFKAVFYKPHEEHHAFEGGRSRH
The following text describes a protein:
Function:
Meiotic recombination factor component of recombination bridges involved in meiotic double-strand break repair. Modulates the localization of recombinases DMC1:RAD51 to meiotic double-strand break (DSB) sites through the interaction with and stabilization of the BRCA2:HSF2BP complex during meiotic recombination. Indispensable for the DSB repair, homologous synapsis, and crossover formation that are needed for progression past metaphase I, is essential for spermatogenesis and male fertility.
Subcellular Localization:
Chromosome. Note=During meiosis, recruited to chromosomes and localizes on recombination sites in a double-strand break-dependent manner. First appears on the chromosome axis at leptotene. Along with the progression of meiotic recombination, released from the axis to form bridge-like structures linking homolog axes before they are synapsed. Finally, located between synapsed homolog axes and on the synaptonemal complex (SC).
Sequence:
MTKRKKLRTSGEGLCPPKPLKNPRLGDFYGDPQSSMLGCLHHPEEPEGKLGPVPSTQQHGEEPGKAVSSSPDEETGSPCRLLRQPEKEPAPLPPSQNSFGRFVPQFAKSRKTVTRKEEMKDEDRGSGAFSLETIAESSAQSPGCQLLVETLGVPLQEATELGDPTQADSARPEQSSQSPVQAVPGSGDSQPDDPPDRGTGLSASQRASQDHLSEQGADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGEGTHSSLGCSSLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGHRRALPGCTSLTGETTGESGEAGQDGKPPGDVLVGPTASLALAPGSGESMMGAGDSGHASPDTGPCVNQKQEPGPAQEEAELGGQNLERDLEGFRVSPQASVVLEHREIADDPLQEPGAQQGIPDTTSELAGQRDHLPHSADQGTWADSLAVELDFLLDSQIQDALDASDFEAPPEQLFPSGNKPGPCWPGPSSHANGDPVAVAKAQPRTFVGIQASEASRMEDATNVVRGLIVELSNLNRLIMGTHRDLEAFKRLNYRKTKLGGKAPLPYPSKGPGNIPRGDPPWREL
The following text describes a protein:
Function:
Required, with oct-8, for the localization of a subset of 7 transmembrane domain odorant receptors, including odr-10, to the cilia of olfactory neurons AWA and AWC. Regulates chemotaxis responses to benzaldehyde, diacetyl and 2,4,5-trimethylthiazole in AWA and AWC neurons. Plays a role in nociceptive neurons to mediate avoidance of high oxygen.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein. Cell projection, dendrite. Cell projection, axon. Note=Punctate expression in dendrite and axons.
Sequence:
MTRNRRKSKTTATSHPELHLEKVDPMKTVTESMILFDVQLQEWVTKSAKNHEFVLSDKGIPASAYFLLGSFCSDGDIHVAYASKCPVHSSALEENATESSKMLEDEWMSDHAERLLRMLPGGIHVVGIAWFSDKKTFSDRKSHIHKTLGRIQKMNNQITTANVDDSISDNMITVFFETPSTTPIGAIIDVTNRGNDSAQKVQFQKLEWISLVTNASARIVHNVPVDTGRPTDFYSDLVVATKNFVNNLFQCEFTLLDGEIRDDKEPLIKDIKKNKKTTIEAQLFLNPLYNRELGAIDDIASNMHEVLFDIEVRAAVPIRSTVKDAIRAIKHHLVRNLFARVELHYESMEVVEEERSPKTGITVHQLPRPATTVLYTHPAILINDFLFEADNVEDAQKNFDDMMDLQTSIEHVDEGWERALTPEEMEAVRTPIEDLHFVDFDGSSDSWCTTKTILITIALIIGLLASIIYFTVAHS
The following text describes a protein:
Function:
Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate. It can also use succinate as an acceptor.
Sequence:
MSTPLQGIKVLDFTGVQSGPSCTQMLAWFGADVIKIERPGVGDVTRHQLRDIPDIDALYFTMLNSNKRSIELNTKTAEGKEVMEKLIREADILVENFHPGAIDHMGFTWEHIQEINPRLIFGSIKGFDECSPYVNVKAYENVAQAAGGAASTTGFWDGPPLVSAAALGDSNTGMHLLIGLLAALLHREKTGRGQRVTMSMQDAVLNLCRVKLRDQQRLDKLGYLEEYPQYPNGTFGDAVPRGGNAGGGGQPGWILKCKGWETDPNAYIYFTIQEQNWENTCKAIGKPEWITDPAYSTAHARQPHIFDIFAEIEKYTVTIDKHEAVAYLTQFDIPCAPVLSMKEISLDPSLRQSGSVVEVEQPLRGKYLTVGCPMKFSAFTPDIKAAPLLGEHTAAVLQELGYSDDEIAAMKQNHAI
The following text describes a protein:
Function:
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
Subcellular Localization:
Cytoplasm.
Sequence:
MAVFIGGTGTDVGKTFFSSLILGKYGESLGLKYFKPVQTGDDSDRITLMRLTGLHESYVLKNYYSLAFAGSPHYSSELEGTEIDTDELSRHLYSIRDEKIIIEGAGGLLVPLNRRMLTLEVIRQAEIPLILVAPTSLGAINQTLLSIEAIQNRNIDLKGIYFLGIPDKTTEDNIRTITEWSGVISLGSFFLNSNERISCECFQEECIPKFDLDESIKNILV
The following text describes a protein:
Function:
Importin, which transports target proteins into the nucleus. Specifically mediates the nuclear import of splicing factor serine/arginine (SR) proteins, such as RBM4, SFRS1 and SFRS2, by recognizing phosphorylated SR domains. Also mediates the nuclear import of serine/arginine (SR) protein CPSF6, independently of CPSF6 phosphorylation. The nuclear import process is regulated by the small GTPase Ran that partitions between cytoplasm and nucleus in the predominantly GDP- and GTP-bound form, respectively. Importin associates with target cargo proteins in the cytoplasm, and the competitive binding of GTP-bound Ran induces the release of cargos in the nucleus.
Subcellular Localization:
Cytoplasm. Nucleus envelope.
Sequence:
TMSVSQNANNVLQAVNNLYHNPNPADKEKASKWLGEFQRSVFAWETADQLLQLKNEVESTYFAAQTMRTKILFSFRELPAETHESLKESLLNHIEQLANMSPILTTQLCLAVSDLALQMPSWKMPAVTFMQKYGKDHSSLSYLLELLTVLPEEVNNKSLRLGANRRSEIIDQMEDSAPMVVELLKTYIGKRAVSDEKLLSKIFKCLASWFYLGVLPGNHVARSKLLEVPFSVLKDISMSSSLYESACDCVCAALYATEDVTKNSDLVQLLFEGAHSLREAYHSAIAHEDTDKCLNLCRVFTELAESLLEMLVNMPGDGLGDLVTLDLLLLCNGHCQYEVAEITFNFWYRLSEMLYSSNEDIVRQVFGPYIERLICSLVRHCQMEPDNDKVLDENNDFSDFRSRVAELVRDVVFLVGPTECFIHLFSMLSSTSPPSTWDVTEATLFIMSSIAKHVKTSEGSVVPQVLQAILSLPSETHIAVRHTSVQLVGELSAWIEKHPDFLDHTLQFLTTALQCQELASVAATALQYLCEVCCQQMAQHYPALLQLMQVSDELKVSADATLGLLKAGVVTVLRHLPTQQIKEAITHLCSMQVVVLGQQITDSNNSGQTKDPTIWLDRLATIFRNVNVTSQNGSVHPCKEAIEQMWPVLKSVLEKIKSENRIVERWCRCVRFAVRSAGRSIQSTMLNLISETITHTYLTDPHSCFLYLGSVLVDEYGIDTSLSTMLGSFAEPTFKMLNEKDGLSEHPDTVDDMFRLCSRFLEKCPAHFLSHPACPALLNCALVGLKHEHRDANASVTKFLRNVMECKISNTHKASGEGGQHIIEQVIESYGGQIVEQSLQACLFHIPTYMYPDVAELWWAIIERNRQAFSTWFMSALKNLPTEATLATATPEQTLQFHAEVTVATEWKIVSYHLRDFCRLYR
The following text describes a protein:
Function:
MFS transporter involved in N-acetylglucosamine (GlcNAc) uptake. Confers resistance to cycloheximide, 4-nitroquinoline-N-oxide, and 1,10-phenanthroline, and contributes to virulence.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSHATDSTLDNASVDSEKVRDFGDDLQNHPVQPTRSILSKIRSRDDDARSLVSNNKGVERIISDLQEGAGQLGPLEQPYDIKKIETHPDPHTDYNEADPWKYPIDSESGLRLVEWVDGDKHNPKNISKAKKWLYTLVLGAVCFVVALGSAIVTGDMERPAEYFGVSEEVIILASVTVFVIGFGVGPLVFAPMSEEVGRKPIYVVTLFIAVVFIVPCGAAKNIATLIVCRLIDGIAFSAPMTLIGGSLADIWEGPERGTAMAIFSAAPFLGPVCGPIFGGLLCDHAPTWRWIYWTFLIVAGVFYAIFIAIVPETHHGILLKKRAKKLRKETGDSRYRSFNELQIRSFGEVAKTSLLRPFVLLSELIVFLMTIYMAICYGLLYMFFFAYPVVYQQGKGWSASLTGVMFIPIGVGVIIATIAAPFFNKDYNRRAQVYRDRGELPPPELRLIPMMIACWFVPVGLFAFAWSSYTWVSWAGPCFSGLAAGFGFCCLYNPANNYIVDSYQHYAASALAAKTFVRSIWGACVPLFTIQMYHRLGDQWATSLMAFISLACCAIPYLFFFFGARVRTFSRYAYTPETNTK
The following text describes a protein:
Function:
This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Synapse. Cell projection, filopodium membrane; Peripheral membrane protein.
Sequence:
MLCCIRRTKQVEKNEEADQKIEQDGNKPEDKAHKAATKIQASFRGHIIRKKLKDEKKEDGTAAPEAAAAADGVENKEEKASSPAAESKEPAAEAVDEPSTANAEAKREEADAVETSKDEAKPAAATDPSEKAKDVASPEEKAAAATEGENKEAPPAQESATTTSASTESAQSPNAVEPAEKKEPQQADVPAADASETTPKVQSEETDSNQPQDKQDAVEESKPAESDHTEETKVEDIKADQENV
The following text describes a protein:
Function:
May be involved in testis development (By similarity). May play a role in hematopoietic differentiation or inflammation. Has immunomodulatory and antimicrobial functions against Francisella tularensis, a Gram-negative bacteria.
Subcellular Localization:
Secreted. Note=May be targeted through the Golgi via the secretory pathway.
Sequence:
MSSPQRRKAMPWALSLLLMGFQLLVTYAWCSEEEMGGNNKIVQDPMFLATVEFALNTFNVQSKEEHAYRLLRVLSSWREDSMDRKWRGKMVFSMNLQLRQTVCRKFEDDIDNCPFQESLELNNVRQGISFPQVHSCGCCMGCGVGTGAADKAIPRDKGK
The following text describes a protein:
Function:
Nucleotidyltransferase involved in the post-translational modification of proteins. It can catalyze the addition of adenosine monophosphate (AMP) or uridine monophosphate (UMP) to a protein, resulting in modifications known as AMPylation and UMPylation.
Sequence:
MTNPFLNLTYEPALESLGNEFFDPVSAATFPEHKLRFRNDRLLPMLGLEPSQVKDDNFVEAFGLFHGVRPFLALRYHGYQFGEYNPNLGDGRGFLYGQVRGVNGELFDFGTKGSGQTPYSRGGDGRLTLKGGVREVLAAEALHRLGVKTSRCLSLVETGDSLWRGDEPSPTRASVMIRFSRSHIRFGTFERLHYHHQTEQIAQLLDHVIVTYYPEVSGSNSDDSAHIAFFRVLVERVAKLVAQWMAAGFCHGVLNTDNMSITGESFDYGPYGFVPTYDLNFIAAYFDYGGRYRFGNQPAVCRWNLERLQVSLSSVIPSKAMTEALEDYEKIYLGYYITLIARRLGISSTLGDRLDPELWEKLVGQTLQCLAQSQWSYPDFFAQLRLNFSPSWRDNADLILENVDLLGADWSTWRSIYQQVLKQLPPESLAAVPTVLEQANPLTDLLRPRIETVWQAIAEDDNWQPFNDLVQKLQSGN
The following text describes a protein:
Function:
This is one of the chains of the nonenzymatic component (CF(0) subunit) of the mitochondrial ATPase complex.
Subcellular Localization:
Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MPQLDKFTYFTQFFWSCLFLFTFYIPICNDGDGVLGISRILKLRNQLVSHRGNNIRSNDPNSLEDILRKGFSTGVSYMYSSLFEVSQWCNVVDLLGKRSQITLISCFGEISGSRGMERNIFYLISKSSYSTSSNPGWGITCRNDIMLIHVPHGQGNIVF
The following text describes a protein:
Function:
Probable transcriptional factor. Binds to the promoter of the SQUAMOSA gene.
Subcellular Localization:
Nucleus.
Sequence:
MEPLSYGLEGRGFLFPDNVELSVDTFSRSRNTVKEWNLNPFCDVDKSICGPSQEITESTGFLESGIADIFKKSAASNPCPGALSGEIGNGSMLELGAMFNHSATKSNNPMSLPIGLKLDELTDYGEVRTSQSSKESSVLSSPESSLPTGKAAQRKSLHSQFPISQVRGQKEEESIVYREVKSNQSLKRNPDLSTVNSSLQGKRLRTTNLHSEVPFCQVHGCNKDLTSSKDYHKRHKVCDEHSKTAIVIVNGIEQRFCQQCSRFHLLAEFDEGKRSCRKRLAGHNERRRKPQFDSHWGSRFLDMTQRRVPFLFPEILPGSFFYQENYEVNNNDQHLRLDRKPFCISQLAMSVTSGQSPAESNQHQYGVRKQDLSKVPVGSTILSVQEISAGQNSSCALSLLSAHSQNLLRNSTGISPTLPWMVKGDAHAYIKDDHHNLAKSPRVSVPEMQRDGHDQRANSMNSKNCLSPEGGPTMDLVQLSSHLLRVEQQKNSVQVKQENDIFSSFAST
The following text describes a protein:
Function:
Influences the temperature-dependent expression of several E.coli envelope proteins, most notably the porins OmpF and OmpC and the lambda receptor, LamB.
Sequence:
MQLSSSEPCVVILTEKEVEVSVNNHATFTLPKNYLAAFACNNNVIELSTLNHVLITHINRNIINDYLLFLNKNLTCVKPWSRLATPVIACHSRTPEVFRLAANHSKQQPSRPCEAELTRALLFTVLSNFLEQSRFIALLMYILRSSVRDSVCRIIQSDIQHYWNLRIVASSLCLSPSLLKKKLKNENTSYSQIVTECRMRYAVQMLLMDNKNITQVAQLCGYSSTSYFISVFKAFYGLTPLNYLAKQRQKVMW
The following text describes a protein:
Function:
Involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond. Involved in cell wall biosynthesis (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MEEKRVKCKKKLTSTIGTWKYIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNLLLQWKSLDKQIVLLGDDTWDVLFHDYLNETLSQPAFSFNVPDLHGVDNKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDDSTLLIVMGDHGMDNKGNHGGDSFDEINSVLWMYSKKPTFGYLKQPGKVLSANQVDLVPTLSLLLGNPIPYGNLGTLIPEPFYYYGDEYLSKAQKINIGQLNRFFSEYDLDASDFLSSSVHKNNNSYLDQYFLDFDYARDAFSYFKAIWAEFSLFPMIIGFLLLIIGGFNLALLMQDKSVIFRMSANMAPSVMKCLPVCLILILANNELHSPFPAEFYVLLPSFYILLNSFNQKLMEYFKGFVKLDYFSIFITFLHVCSFGSNSFTVWEDRLCHFLIITIGLVMFCKCFSEMSPLFACSTYSALAFILLQVISSYVTNCREEQGAFCVSTYISTPDNSLRTLIVLALMALSSIILPLILQLHLRRVLGLSLKLYHLSILYFFELISSIFWIAHHVFANDALLEKQYHHVLYSLANTYVICILGVLIWQFFLLSRSKFAKINVIERSYFVFALLYSFLSFLQRPLGHLSLFSCFLQILLLIQLKQWQPSVGHNFFSVTLGLLGLSHFFTTGNQAAISSLDWNFAFIHSKSAENQAISAIFMFLHTVGAPILTCISIPLFSFEPLSKKNRFLINLFRFSFSFILYNLLISTSTVFFAGFFRRHLMVWKVFAPRFMLSGILLVTHQLFVLIQCFGSSVVKFPEDAE