The following text describes a protein:
Function:
Involved in negative regulation of lysosome biogenesis, by limiting the heterotypic fusion of early endosomes and postlysosomal compartments.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Lysosome. Endosome. Note=Also found in post-lysosome.
Sequence:
MNRNFNNINNNNNNNNNYHGYQYHQQQQQQNQQQQQQQYNNNVIKYLWNTYTQTVVYQDSLFNLVEFLQFFTLNYYNDTIGDLLFLSNGTLTDITRHLSKHLIEEIGYSCTLLNQQQQTQQTQTQTQSKQQTIPQLSLNNSIPTSFTTTASSTNTTPNAGLKLAEYEIYQYLIGYSTAGEGPLVLAALDILSRQSPNGIPLSFLNFLITILLRILSLPPELLYNNNNNDNNNNINNFSGNNNNNFNNNNHYFNNNHNNHNHHYQHHQLKEKKKNVNKQHFKPIESFFYLQPLPSSLSDMFRDDDYASLSSSYGGGGNLTPLSLSSNHAFSPPLSSLKNSSSNTFTKPSSSTTTTTTTTTQTPTPNSNTDSKQNKDNNNSKNNNKEVSSVVLLGYQILKIVENLVKDKLFLYELVTSDCFSQLLNIFYKLPILSTTASSLPPNSSFSIIYQQLSQIFAQIMSKSCLSSDTIVLIHNFKLIKNLLNIMDKLKEKDEYNMNLIIELNKIILFSIKSSTSITKLLHDDFTKANGYSILLNSMIFISDYGTLKNKIDYIQTTTNLLFIGHRSSYLDKANTKMFEIYLNVFSISTSEETKTELLKCIKGVFYTSLIEESSSSSSLIISSSDNNNNNNNNSDGVNDDKNNNNNNRDNIIFEDVIDMDGNDSYLIFHQFQPFTILFSQFDTLNINNRRMILDMMDVLLTKNRISLNELKEYCNLFKSELPSTVLLVSQHLTELLTKGKVSCDVLGRDLSLTQKLLEFLVNDPTTLRFSSILLQNETELQLCFSILSTNNNNNNSSSKYYSNNIQQQQQQQQQQQQQQKKRHVSRYLVLYMIVTEILSLLLELLVPPSIQTIFIQECQGLKLLYPMLLDEYLIQPALKVIASIAIGGLQLESRIIPDLIMELQNNGGGATNLDSKVLTMRKNIFSSMCYIFHNNPNSKNSFRNFQGFTWSLSILDGISRYLISIDNNNNNSSNNNSNDNLNDFKESLDHSCNGVLNSNNSSNNSNLNGGIGNEIKKSSFNEIFYFLKVLIDMLSAAMKNNSINQEYFRKEIIIISRSLKQCKYMEGIHAISLCDSLLNMAITGSWPPSCENHSLEEGSLFSLYSPITSFFPINTTLSKNFDISFILKFEKKEQMEQQLKQQILLNSNNNINNGNGGSISPSSIINNMNSPGGGSSSSNDSLKSPTRRSRSYTNDFHLDKSSRIPHPPDFNNNNDTMNYDYNFQDDYIESLNSKSSSSFSLDLASVTGDSEIVYYGGSTTSRMIHSPGLPSSSLQALSSNSTKLPEKSSLQLAQERYICCQSCRDTLTLEMPEIFKLIIELMSSDDDISQTEIKSSCYIIRELIFLTNCSLANQKRLSSLLIDIITHFKPLLLSIILYQKQQQQQQQQQQQSNSNSNSNSTIILKKKINNETSTKLKPLLLDLIQTLAGHNLTLIEFRKYFELLKVKDSNNQFIYPIDLLNLLLKISSNRDNIPLYYAELSKHGLEYIDFPSWGERTWPPTKGFGISFWFRYSLPCLNINKSPIYLLSIEGSIGNSSTKSCECQLILENGKLVYKIYHFSGICETYHFSDHKFEPDQFYHISISHSSLLSTTTTTATTANTTTNSTTASTTTTTTNSTTAVSSTTNSISTTAAVAAITTSDGNSGISRENSLGGRDSIGSNSSSSSSSSNSGVSSGSSTNLNKKSPVKLYVNGCLRGQILANYPKSNSMTLYIRFGGVNAASSVISNNQDVQSFNVNNSWNLGNAYFFEEVPLDKEIFYLYLLGPNHFRGLKVDLSAVDSIQPSLDKVSNLHPFLIDHLLNPTVQPLLSLHEKIMYIFTAKCLYVTTHRITNKTESVTHASALPQLSTILFQQQQLQQQQLQQQITNSTTSILNELNLSNSINLIRRGSENSLITSSSSSSLSLSLSSNTNNNNNNNTRSSLERSISGNFLQSPSSSNNNLRERSINNNNNNNNNSNNNNNNNSISSSTSSLSSSVISLVAGAMAVPSPPSPNKLGSGINGSSILNASLTTLSISTNNNSNNSNNSNSNNNNNNNNTNYNSNSLNNSLNHQALSLLHTGLPIALPRGVISQIGVKDAIMNSGGVSVIIYLIAMAEDKEYQRSGLKLLQSIIHNSQLNLKDMKEISGYQLVSFLIRKKNWVLDDQLLSILFSFVGIQSTRTSIHYVDGVVQDVLALKHFLLERSIWRRASLIDQKKLFESLEKLVNVLHENHEFNIIKFRQAGAYETILKMCREDDLPLELLSTLTKILRSITTNKSNKLKDDLQLILSWLLETMPKQQIFKKYNSFNGLNSTNNSNNNNNNPISLFRKGRKTLLQVQFDNHQLYLQQQQQQNLIPQVNSNNNNEESNNGIEGIIRINILNLLLDILSKTELSVVEDFHSICSLETIFGLLTCESMVSRVMFLKIIDIFLHSQMIFGHFQKMKGFHLLGHQLLPFETSEKIFGVLFCILFGKPSNSDILEGLSMRMYFLSHLSDAEMKYPGAIVTILIILCNSNSTTQHNVIKMIHNIFLQNDQFKQSLLDNELIPRLVDILSSNYQRRGSSSSSTNSTTNNNNNNSSTTTTSNNNNNNNENNNEDDWVAEESILSLLKEIALYGAKSQDGSAALLRDILVVLHLNTRMDYDYICCLQRRVLFDVISFFNDNIHSFSSIDSLVSSFEKLCVLTIHTLSYQEKLLLTNGTGTGGGTGGSGGGLLTKKSFRSNLFSPSRSKEKEKEKEKEKEKEKEKEKERERERETTNVTSDSDNILSANDIFYGDQSNEESSTTDSDSTSDNNNNNNRNSYSGRNIRGNGINNNNNKNKFIPIWIKEGNLLDQEEFIRSLLKVLSKSKIPQSNTTYRNLFSTQYSARSLLCKFIFILLTFDEFKDYYLMVLQELSNMVPSLSNTPISSSPIISPINNNNNYYNTNSNTNSNSSTPSLFSITSNNNNNNNNNNNNNNNNNNNNNTNSTNQTITDTTLSPASSNVSISNQSTPISNNNNNNNSSGGGSGGSNINIPPTINISDSNSNSNEQQGISSVLSEIIMEEDFILVLLHITHKFLQSGNDYEIQRNSFRLWVSIIQHCSQVDYVKKAFDTTTTSLAVLSSSQEIRDLLIRYQQIYVENEFKKWEEKFNQSKKEWKLQYFETQKNKQSMITKNQDITKSTKKLSDSLIQLKSEYEKSNYQYLIENRESKRFFQSQWKLLIKKVTHEKAIWSPNYEISNSSSTNITTTTTTTTTAKKWKLDPTEGLNRMRMRLKVISDNTSNSHIPLIPDLSTPSTPPSPQNTKDQLLFNFNNYNNNNNNNNNNGLNAPPLHGSLDYSSFDNLKLGEKVNEVFKCSCISPFYQRDGELLIGDQNVYFLDELLTSADRKKTTASTVGGSNNNNNNNNNNNNNNNNNNNNSNDTTSSINSTTATNTNTTNTTTTNTTTTTTTTNGLSNIVKPPQRGKHITWSYDDIIEIHKRRHVLKNNAIEIFLGSGVPHKTYLFAFNKPSDRDIVYDLIMSKPLPNRVDYAAEVHGNILKMSITKKWQSGLISNFEYLMHLNTLAGRSFNDLTQYPIFPFILRDYESEVLDLENPNTFRDFTKPMGAQDPKRLEKFIEKYNDLLEMNEKPYHYGSHYSNIGSVLHFLVRLQPFTSYFIDFQGGRFDVPDRAFHSIAQSWNLSSSISNSDVKELIPEFFYLSDFLVNSNKFFMGIKQNGVKVDDVILPPWAHNDPRLFIKKHNEALECKYVSENLHHWIDLLFGYKQQGEAAVKAHNMFFPLTYEGAVDIDSIEDQLNRDAAVAQIHSYGQTPKQIFTKPHPKKNWSKTIRLTQDSIFTKPERLTSYIMFQYRSPIGSITIANDSSPIHLTPQRILFFPDNNKSISWGHWDQNLRVNSIDTGKVLSIIEVLNDDIICGDITKNGRLFVTGGTAGTVKVWKRCNNDGTIMTRKERGDNLSLWSTLYGHTNSILCVTVSQEYSIIVSGSKDSNCIIWDLNRLTYINSLQHDHPVTCVQVSPTFGYIATFETNIYNKQNNNSGGGGSKNDNSINGSGCLRLWSINGTLLAKQNFVNDRVNCMIFTSTIQGVNTNLLITGMESGTIILWNAWNLQKIRTLVSKSTITALAVSKDNTQLISGDINGLIECLSSRSFDGYSSIVLG