lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
DNVYSILAVWGLALAYRRIDDDEGKAYELEHATIKCMRGLLSSMIRQADKVELFKNTQALEHALHAKYSTTTGATVVGDREWGHLQIDATSIFILILAQMTASGLHIIYTLDEVHFIQNLVFYIERAYRTPDYGVWERGNKMNHGQPELNCSSIGMVVAALQAINGINLFGSRGGPLSVIHVLPDEITRNVTTLHSALPRESASKEVDGALLAVISFPAFAVSDPKLVERTRLEVIKKLGGRYGCKRFLRDGHQTEVEDPSRLHYEPNELKIFEGVESEWPLFFAYLILEGLFRGDMEQVEHYRAMMEPILIDSSQNMRLVPELFIVPLASIDAERANPGSQERVPNANVPLVWAQSLYILGNLIYDGLLSVADIDPLNRRLIPNTLRQELDTVVQLVFLSETAELQSKLRMYGLETQTLANCEPITISPPSALRDAMQVLGENQKLKLSGRPKRPMGTLSTCKIYRCQGQLYAFLPHFMNSEEFYLVSDNDYLVSLFEQELAFIKNHWYSNGRPTMVVMLTNEMLSDVVRATNPTQAPTQRNGLNVSNNKQKLLNFMMSLRSSGVCNGVRIRVGRLSEMINTACIESLDFLVDTQNADYENWQEILRGQGPLQTDESSQHLVIKGVSGSNQFDKDTNHASAKHRRMLRKFSTNSDSPIQARNALSSPYTAQFDESDDSKIAHSAAATDSIKTSAPAMSSDTAQNGPLKNTSTNTATGELLSLTLGNPSQVEAAVALLRISANLYDQADLLHYIYSCKGIDYQVPGLCSLPTLLEEVYVKAMHMKQWSVVRQIAGLLHKTVSSLTSNLSDLLVRQKPVTVGFGALEYFINEPKNPSALADIIYTHCSSDIREAPLIQEIVTYLGSFIRGSPHLFDGIMRIRTHFFVIAMREEISRIQGCDEEEAVEMLMQLSPFEMKSLMDQVLTARDKVNLLSSDYIPTPMAGDMPSRVVHVDTNEAVKQKKTQKGSEGALSTFCALEKVEADEGGSSMACIPETFGKWLRRRKNDGALNRVPKDFYPKVWRLLNKTNGLAIGKSLLPRDPVVGEMTPEELNFALRVEALYDHIRDPAERQIAVELIVVIARIEE
The following text describes a protein:
Function:
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
Subcellular Localization:
Mitochondrion outer membrane; Multi-pass membrane protein.
Sequence:
MAHIHTSTVAVRGHQPACCSKPADTVMESSNIQGKKVAIVGGGLVGALNACFFAKRGFHVDVYEAREDMRVSSFARGRSINLALSHRGRQALQAVGLEEQIVSKGIPMHARRIHTPLGKKYSIPYGKKNQYILSVDRANLNRELLTAAEKYSNTKLYFGHKLIECNAELGTLIIKRAVPKDSPSSRSGQLPLEVTYDLIVGCDGAFSTVRKQFMRQTRFNYSHEYIPHGYMELTIPPRDGDFAMEPNYLHIWPRNTFMMIALPNMDKSFTCTLFMPFEEFEKLVTGEQVLDFFQTYFPDSIPLIGERELKHDYFLLPAQAMISVKCSSYHLSSHCVLMGDAAHAVVPFYGQGMNAGFEDCLVFDELMDQFHNDLGACLPEFTRLRVPDDHAISDLAMYNYIEMREHVNSTWFIFRKQINNLLHTLMPSTIIPLYTMVTFSRIRYHEALQRWKWQEKIINRGLFIMGAAGLGGTYLLIKKLTRGWYFIPNLWGWCHYLRNIGIFPFSTQVAKM
The following text describes a protein:
Function:
Required for the formation of cilia. May also have pro-apoptotic function (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium basal body.
Sequence:
MSEDSRRVEDDDRGPGAAYQAFLMMEDLLDKLKLLSYEDEVLRKQNMKPLSRHYFALPTNPGEQFYMFCTLAAWLISKAGHHFDQPQEYDDPNATISNILSELRSFGYSVDFPPSRLKAGYGEQVCYVLDCFAEEVLKHIHFSWKRPTYPTEEQDEENVIEDDAELTLNKIEDEIAEEDSDNDQEHFIDLNALSAQTQKLNTKESSKPEEILESNTDAAEWILEVERVLPQLKVTIRTDNKDWRVHVDQMHQHRDGIDTSLKETKGYLDKLHNEVAKALEKVSSREKYINNQLEQLVQEYRSVQAQLSEAKERYQQASGGVTERTRILAEITEELEKVKQEMEEKGSSMTDGAPLVKIKQALTKLKHEIVQMDIRTGVVEHTLLQSTLKEKSNMTRDMHALNIPESSIGAY
The following text describes a protein:
Function:
Acts as a component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.
Subcellular Localization:
Golgi apparatus membrane; Peripheral membrane protein.
Sequence:
MAAVQPSRGSSQPGPSRLDGSGPSSTQASTRPLAARVRSVLLHAPRDSNNICKALDTLAHMYPAASTQSTLTDHQIFSGSSGANTSAASTTAPLRLVDTARARRDLDSDVRQRMLTATEDIISVLRTVDHGLVRLSNDVAAMHSSCDAVQHKLTAAHDSSRYLVEHAEGLESQRAAALTQLQVAKLFLSRFTLSEQERASIDSREVRVSNHLFHAMDKLERIRSECQVLLQGSESIPSGANSASSMSAAASVGGGTRAGMDIMSSTAQDLDHAYQKLYKWCSFEFRQPVKEGLEVSPSLREATHRLKHARHDLLRSALSTLVQTRSSILANAFMAALTMGAGPPTYLPGPIELHAHDPIRYVGDMLAWIHQTVASEREFLTSLFNEKEGEGGRRIGQKRRGLEGSLDLTGADPESLQLGPGEALVREVLNSNLDGCCRPLRLRIQQTLCSQEGSVSSYRLAHLVHFYRSTMQKTIGSRATLSRTLGELSDLAVSAFAETVERQSRGIDRYDGLPEPDLSLPPPLVATIGTLKELTGEFSRSLAEDAPWSPSQAETEAPGTMPTEESTAASLSNFDFVLIKLVDPLVSMVRRLAALHIAKRPRSRTEATARWESLLFTCNCLEALTSTLDTYSFAQWKAGQMRSTFETTLAEVTNLHSQQLLDRAGLSSVLTAMAGQNDGSVALSSVTGATQAEMNRALTRFDQCLTQDDLLSPKGLEALASPTARQTVHITALQRLTESYARLVEAIESPQNGYESTKQMIKRRPEAVAILLGL
The following text describes a protein:
Function:
Plasma membrane magnesium transporter.
Subcellular Localization:
Cell membrane. Endomembrane system; Multi-pass membrane protein.
Sequence:
MSDSESYYQNSTTNQPIPRSDEVLDDHRNQITNDCAISDSEDELELKPELESEVVKSEKQQQQHHQEITSDNAKPLTRKSGSSIKKKSNLTDKDRITNPMSLSGGDDTINSGHKNRNYNMSSLRKDFYLKDNTDDNSTNNHTHLAIPIPIPIPTPIITNANKSRRKSQLENLPPLIKKKTIGRNNSNNFENDLVSPMTKMKTNDSEDITNTTSTTANHMKLGIGATTLGVGTGTTATATATATAGGGGRRPSRSSIDSEADSHASRSSQETEEDVCFPMVGDHIRVNGIDFDEIDEFIREEREEAYLQKQMIAKNISRIDEFQNLSKTNTTSGASRHPYHHHSNNNKKNNGGDGSSGSSMAALKYTPKNILKKTLSRFEFTHENSSSSEEIYELKTKQQPPYKYDDQLSLTSSTSSTSGSGSGQVKFGGARISDGINGGSLPDRFSLFHSESEETIHAPDIPSLVSPGQSVRDLFRNGEETWWLDCTCPTDSEMKMLAKAFGIHPLTAEDIRMQETREKVELFKSYYFVCFHTFEADKESEDYLEPINVYIVVFHDGILTFHFSPISHPANVRRRVRQLRDYVDVSADWLCYALIDEITDGFAPVIHGIEYEADAIEDAVFTARDTDFSSMLQRIGESRRKVMTLMRLLSGKADVIKMFAKRCQEEANSSSGYYQRQYNLQQQQQQQAPPPPPPNPIITSPINSTLNLNSLGTSTGGGVGVGGINFGPNPTGNNTNTNTNTTGSPSPPQQQQHGITNKSFPIPDARPRADIALYLGDIQDHIITMFQNLLAYEKIFSRSHSNYLAQLQVESFNSNNKITEMFSKITLIGTMLVPLNLVTGLFGMNVRVPGEGGKNLGWFFGIVGVLIFIIIGSFIFAQWWLKKLNNSIEGQNNGNRPIFNHSSRRSIRSLGLKKHGGNKSIISFPNKYE
The following text describes a protein:
Function:
Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
Subcellular Localization:
Cell membrane.
Sequence:
MPRRYDHDAPDDFEDDSAEQGSRWQRRLIVWSLAAFALALGFLIPYTMYLNKQVTQRFGELRWQIPTRVYGRPLVLVPGKALDAATLKTELDAASYRDDGLGKLAGTYQQDGSRFVIASRGYIDVDGQVPARRIEVALSAGRVASVRDAADRKALKSARLDPARIATLYGQKQEERRLVRMEEVPELLVTGLQAVEDRDFNSHHGIDLSGMVRAAWIMARSGGQVRQGASTLTQQLARSGLLGIGKEQTVTRKFNEILYAVIMEARYDKRTILEAYLNQVYLGQRGGQAVHGVSSGAELWFGRELGSMTTEQVALLIGLVKGPSYYDPRRSPARALDRRNFVLGKLRENNLIDEAEYKRALAAPLGVPKEPGLVAANRFPAYVDLVRRQLAHDYPESVLQGAGMSVLTGMSPSAQAYAEGAVTGTIKRLDNKKRPPLQAGLVLTDVHNGDVLAVVGSRDVAKPGFNRAVEAQRQVGSLLKPFVYLLALASPDRWALSSWVDDSPVTVQLARGKTWSPGNSDNRSHGTVRLIDALAHSYNQATVRVGMQVGPERVAQLIQVLAGIKAETNPSLILGATDQSPYGMAQLYQFLAAGGEIQPLHAVRGVLDPQGKLLKRYDKTPAPAQEGDSVAANLISIGLQQVVSGGTARQLLGDGLGRLSPAGKTGTSNDGRDSWYAGYTGDHLAVIWMGNDQNAETGLYGATGSMRVWSSIFARLPSAPLKVSGKGLDWQWVDASGIGVTDAGCPGARQFPFVVGFTPAYASCAGNAPSIEEAPADGSAPAEQSSGGGWRRFFGLDKKTETPAAAPASPPPAH
The following text describes a protein:
Function:
N-acetyltransferase involved in oxidative stress resistance. Acetylates the toxic proline metabolism intermediate (S)-1-pyrroline-5-carboxylate (P5C), or more likely its spontaneously forming tautomer glutamate-5-semialdehyde (GSA) into N-acetyl-GSA for arginine synthesis in the mitochondria. P5C has been shown to increase the levels of reactive oxygen species (ROS) in the cell by inhibiting the function of the respiratory chain in the mitochondria. The enzyme is able to reduce intracellular ROS levels under P5C-induced oxidative stress and protects cells from damage by oxidative stress (By similarity). Also acetylates and thereby detoxifies the proline analog azetidine-2-carboxylate (AZC), however it is unlikely that AZC is a natural substrate as it occurs only in plants belonging to the Lilaceae family.
Subcellular Localization:
Cytoplasm. Mitochondrion.
Sequence:
MKDPNTIPPWRCTDFNAWCIAVDKSTNVKNKEELLSTLTYFINYEIEMGQTYPIDIKMTRNEAEDFFFKFCTVICVPVESETSPAPDLATASIDWKTSLLGAFYIKPNYPGRCSHICNGGFLVSPSHRSKGIGRNLANAYLYFAPRIGFKSSVFNLVFATNIKSIRLWERLNFTRAGIIKDAGRLKGHEGYVDAYIYQYHFPSLEDALK
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
MQPNAFHKLLLLLPLAYQHTSNDHKDESHWDYETNGQNWGGICSTGERQSPISLNVQKSLIVPLPRIVFGNYDVKLRGPLTLLNNGHTAHVEIPETANGNKPFITGGLLKGRFVAEAFHFHWGSPSSRGSEHSINQQRFDVEMHIVHRNEKYGDIDEAKNKKDGIAVIGVMLKIVKNPNRIFPGLSKVMSALPRVTKYNAKTTIPGGLSLGQMLGNVNPRDFFTYRGSLTTPLCEQSVTWTVFSQVLPVPYSSVSKFWKLRDSEGHRLINNFRDIQPRNGRPVFYRIGKDLSGAYLGK
The following text describes a protein:
Function:
Regulates anaerobic growth on fumarate, nitrite, Fe(3+), TMAO, DMSO, thiosulfate and sulfite, but not on nitrate nor Mn(4+).
Miscellaneous:
MISCELLANEOUS: Possesses 4 cysteines which may bind a metal ion (possibly iron).
Sequence:
MTIEQNKNRRSAASGCAIHCHDCSMGTLCIPFTLNANELDQLDDIIERKKPIQKGEQIFKSGDPLKSLFAIRSGTIKSYTITEQGDEQITGFHLAGDVIGFDGIHAQSHQSFAQALETSMVCEIPFNILDELSGTMPKLRQQIMRLMSNEIMSDQEMILLLSKKNAEERLAAFISNLANRFGNRGFSAKEFRLTMTRGDIGNYLGLTVETISRLLGRFQKSGLIEVKGKYIIIVDHHELNLLAGNARIAR
The following text describes a protein:
Function:
Required to prevent the formation of axillary meristems within the spikelet meristem and permit the subsequent establishment of floral meristem identity. Mediates the transition from spikelet to floret meristem. Determines the transition from panicle branching to spikelet formation. May specify floral organ identity by regulating the class B genes (Agamous-like genes) MADS6 and MADS17, as well as class E genes MADS1, MADS7 and MADS8 in floral meristem. Possesses transactivation activity.
Subcellular Localization:
Nucleus.
Sequence:
MNTRGSGSSSSSSSSQASLMAFSEPPKPASQPSPPSSPMSERPPSGRSRRRAQEPGRFLGVRRRPWGRYAAEIRDPTTKERHWLGTFDTAQEAALAYDRAALSMKGAQARTNFVYTHAAYNYPPFLAPFHAPQYAAAAAAPSSVQYGGGVGAAPHIGSYGHHHHHHHHHGHGAASGASSVGECSTMPVMVPVDPHRSSMSSSLLDMDRNGHDFLFSGADDNSGYLSSVVPESCLRPRGGGAAADHQDMRRYSDADAYGMMGLREDVDDLAQMVAGFWGGGDAADQLGACGFPASGGAADMVASSQGSDSYSPFSFLSH
The following text describes a protein:
Function:
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids. This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode. Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid. Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein. Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome. After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA). The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery (By similarity).
Domain:
Terminal protein domain (TP) is hepadnavirus-specific. Spacer domain is highly variable and separates the TP and RT domains. Polymerase/reverse-transcriptase domain (RT) and ribonuclease H domain (RH) are similar to retrovirus reverse transcriptase/RNase H (By similarity); The polymerase/reverse transcriptase (RT) and ribonuclease H (RH) domains are structured in five subdomains: finger, palm, thumb, connection and RNase H. Within the palm subdomain, the 'primer grip' region is thought to be involved in the positioning of the primer terminus for accommodating the incoming nucleotide. The RH domain stabilizes the association of RT with primer-template (By similarity).
Sequence:
MQKLTRNHWIGLGDCFGGITTVYCGEKLKLLTIFLVCVLGCQLLRNIEVEMPRPLKQSLDQSRWLREAEKQLRVLENLVDSNLEEEKLKPQLSMGEDVQSPGKGEPLHPNVRAPLSHVVRAATIDLPRLGNKLPARHHLGKLSGLYQMKGCTFNPEWKVPDISDTHFNLDVVNECPSRNWKYLTPAKFWPKSISYFPVQVGVKPKYPDNVMQHESIVGKYLTRLYEAGILYKRISKHLVTFKGQPYNWEQQHLVNQHHIYDGATSSKINGRQTDRRRRNTVKPTCRKDDPKRDFDMVRQVSNTRSRVRPCANNGGDKHPPESGSLACWGGKESRIIKSDSSRDSSAPVDSRGRPKSTRSFSPLSRRKTTGNHHHSSVFPSSVEATTRGRSTPGKSVSPRDSSAIPVRTSGASDKNSPLEEENVWYLRGNTSWPNRITGKLFLVDKNSRNTEEARLVVDFSQFSKGKNAMRFPRYWSPNLSTLRRILPVGMPRISLDLSQAFYHLPLNPASSSRLAVSDGQRVYYFRKAPMGVGLSPFLLHLFTTALGSEISRRFNVWTFTYMDDFLLCHPNARHLNAISHAVCSFLQELGIRINFDKTTPSPVNEIRFLGYQIDENFMKIEESRWKELRTVIKKIKVGEWYDWKCIQRFVGHLNFVLPFTKGNIEMLKPMYAAITNQVNFSFSSSYRTLLYKLTMGVCKLRIKPKSSVPLPRVATDATPTHGAISHITGGSAVFAFSKVRDIHVQELLMSCLAKIMIKPRCLLSDSTFVCHKRYQTLPWHFAMLAKQLLKPIQLYFVPSKYNPADGPSRHKPPDWTAFPYTPLSKAIYIPHRLCGT
The following text describes a protein:
Function:
[Isoform 1]: Holin-like protein required for secretion of toxins A and B (TcdA and TcdB). Facilitates the release of toxins to the extracellular environment without causing the bacterial cell lysis; [Isoform 2]: Has weak activity, suggesting that it may act as a antiholin when multiple forms are produced; [Isoform 3]: Has weak activity, suggesting that it may act as a antiholin when multiple forms are produced.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILTISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQDCINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAILLDAMTDEMNAKDEK
The following text describes a protein:
Function:
Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends (By similarity); Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity).
Miscellaneous:
MISCELLANEOUS: Retrotransposons are mobile genetic entities that are able to replicate via an RNA intermediate and a reverse transcription step. In contrast to retroviruses, retrotransposons are non-infectious, lack an envelope and remain intracellular. Ty1 retrotransposons belong to the copia elements (pseudoviridae).
Subcellular Localization:
Cytoplasm. Nucleus.
Domain:
The C-terminal RNA-binding region of CA is sufficient for all its nucleocapsid-like chaperone activities; Integrase core domain contains the D-x(n)-D-x(35)-E motif, named for the phylogenetically conserved glutamic acid and aspartic acid residues and the invariant 35 amino acid spacing between the second and third acidic residues. Each acidic residue of the D,D(35)E motif is independently essential for the 3'-processing and strand transfer activities of purified integrase protein (By similarity).
Sequence:
METFTGYLKSTCFHQISPYPPSIMSIQVKVHANILILSFIECLRMPMHRQIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKLRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYHSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAPMSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKRIIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPDPFKELPPINSHQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMNTWDTDKYYDRKEIDPKRVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDTGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMEKSLTEKLPKLNVPLNPKGKKLRAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISDASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSYLIQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH
The following text describes a protein:
Function:
Involved in cytokinesis.
Subcellular Localization:
Cytoplasm. Note=Component of the cytokinetic actin ring (CAR).
Sequence:
MSHARLSVGSECWVSNNNGHWDAARLIEIKDNGGGKVVATVAKSSGVLETVNYQQLQNRNIGQSESPSDLTNLPYLNEPSVLHALHNRYNNKQIYTYSGIVLVSINPYQNLPEFYNDNLIKHFHKDPEAAKVPHLYSIASSCYHALTTDSKNQTIIVSGESGAGKTVAAKYIMRYLTSVQGVDHNGVVKRSVENQVLATNPIMEAFGNAKTIRNDNSSRFGKYVTISFDENLLITGANVNTYLLERSRVVSLLKGERNYHIFYQLITGCTEEQRDKWFLESASSFNYLSQGNCDEISGVDDSNDFTITCRALSTIGISESRQEDVFCLLAALLHLGNIEVCATRNEAQIQPGDGYLQKAALLLGVDSSTLAKWIVKRQLKTRSETIITSSTLEHAISIRDSVAKYLYSALFLWIVHMINASLDHNKVKRAAYKYIGVVDIYGFEHFEKNSMEQFCINYANEKLQQEFNKHVFKLEQEEYVKEGLDWRLIEYSDNQGCISLIEDKLGILSLLDEECRLPSGNHQSFLQKLNNQLPTKHSQFYKKSRFNDGSFMVKHYALDVSYQVHDFLAKNSDAIPDEFISLLQNSKNEFITYLLDFYMQLVSSQNKNPRKTAISRKPTLSSMFKSSLSQLMTTVSSTNVHYIRCIKPNEEKLPWTFSPPMVLSQLRACGVFETIRISSLGFPARFSYEEFAHRFRILLSSKEWEEDNKKLTLNIVNSVIPHDNLNFQVGRSKIFFRSNVIGNFEEAHRATCSKSTVLLQSAIRGFFTRKEYQRTVKFIIKLQSVIMGWLTRQRFEREKIERAAILIQAHWRSYIQRKRYLSLIKCAIVIQSIVRKNIAYSRYINELRESSATLLAKFWRAYNARKTFRGLKKSVIALQCVSRSVLTRRYLRRLQDSAGRTSILYEKQKNLQASITEVSKQLKSNSKKVTVLRNKLNILNNSLSKWKCLIKKPSDFSEPVSMDFTSNDEQLVQLLQAESKLRQASQQLYMAAKKSELGFVQSQTARENLSNYYQALQMTVSEKFEYDTEQLPSRVLFYAMDRYFSIHKKLKQLLELVGVENASLLPNEVVNKQTKDLLYEKRVVFLKQIKQALTVSSLFNAVGYKDGVMRLLETDQNSLLFAGVVNFLIFAGISLDLKTQISEFLSQLCSYFTKIVDGTVIENDKTLDFYEKPLQAVLYWFATLHKIRSFLVHLLSINSHGKQSVVEDLWNPLILKFSKHFSNLENSFHSLVQKLLSCCTEGSINALLNSKCLPEFIDAADENTTPTGMNIYELIDRMNLIHKLLISSALQPNLLELTISHMLQHIGQRAFQTLIHGRSPYTWKSASQVSYNASLLINWCHQKGISYVNSSLLPLMQSPLVFCLRKNDANDLDVILSVCNLLSPFEVVCLLNRYQPCAGENPLPKSFSKAVEALSCKYKQSGFTNGKITNTNGHAIPIAASKNPLLSLENNHIYEELRLSELINLLAKATL
The following text describes a protein:
Function:
Acts as a negative regulator of abscisic acid (ABA) response.
Subcellular Localization:
Nucleus.
Sequence:
MVSSCGMVEVEENEVELTLGLSIGGCFRRSEEKVTSPCLFEVKYGEAEGSIREKERSLSGSGLSSTVDGGGGEGEGKVRSCGGDDILYPQKRREIHALRRQEARKKREEKQQKKGICKGRRGSCVNGNVPMRIGSLDVKMWVEGQEIQSRVRDREGMENAGTGFDRACKKYKFESTGSDNQQAEEQTLKQNQNHNQNPSAFAAPPFPVVPMQYPFPHLQYVPFTNGFTFPYVMPCWAPPIAAVGNDKNVIQPVACRVFHPFQVPTNQNANKQPPICDSEHDGSKSGVANGTHSSLYSSGSAGSSSSAVSDYQSTSLQGGNSSGTRSHSSHSLSEKPRAQVTVVGKQQGQSEQRVSSPPVGLIQAVDQPTHHITKVVSSNAAPSSPKKPEEEPISGKEPLPTNKPISTAANPPPPHPLKEARVDVKRPPKLPQPPQASPMPHMPYVSTTGNGPNGKTITGFLYRYTKTEVSIICVCHGTSFSPVEFVKHAGGMDVSHPLRHIIVVPPSI
The following text describes a protein:
Function:
May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.
Subcellular Localization:
Membrane; Single-pass type III membrane protein.
Sequence:
MAGLSTDDGGSPKGDVDPFYYDYETVRNGGLIFAALAFIVGLIIILSKRLRCGGKKHRPINEDEL
The following text describes a protein:
Function:
Putative O-methyltransferase.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MTQPVPRLSVPAALALGSAALGAAFATGLFLGRRCPPWRGRREQCLLPPEDSRLWQYLLSRSMREHPALRSLRLLTLEQPQGDSMMTCEQAQLLANLARLIQAKKALDLGTFTGYSALALALALPADGRVVTCEVDAQPPELGRPLWRQAEAEHKIDLRLKPALETLDELLAAGEAGTFDVAVVDADKENCSAYYERCLQLLRPGGILAVLRVLWRGKVLQPPKGDVAAECVRNLNERIRRDVRVYISLLPLGDGLTLAFKI
The following text describes a protein:
Function:
O-mannosyl-transferase that transfers mannosyl residues to the hydroxyl group of serine or threonine residues of proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MNNSPTLSNTRNRKNNNNNSNSNSNSNNNNNNNNNNNNNSNNNNNNNNNVNRNVNNRNNNNNNIINVNNNVSSTTMNMAKDFMNWNDGIIEREDTQLQQQKDRCFKILKKSTIACIVLLFISCTIIYSMTQYPSVSGGDAGELIVVAHQFGVAHPPGYPLFTFLGYIFSHIIPSNTLSVAWKISFMSSMIGSIASIFIYLTVYLWVNNHWCGLLSAYMFTFSPLIWMYQIQGEVFSMNNMFVAMLMFLGVWYTRVRIFENERYNTAFWTSERIAYLSAFSCAIGLTNQHTLVLIVIPFAFWLMFISGRDQLWNIKILSNLVFYTLIGLSPYLLLFITPKLNRVKYSWGNTSTLRGFIKHFLREEYGTLQLYGGDGGVISLFTKISIYIENLIIQFGYIGLALSLIGLLNLLLGYNIRTFKWKSFGTMIIFSFLFYITFFFNLCNLPIDKPLYRGVFLRFFMQPNVIISITMGLGIKSIFGFLNRIQRDGGTAATTTTTISKIQKYLLPIIIILLVGNQIGFNYNLQDQSDNYSFYDYGHSVLDGLPRNTLLLVGGDLVTNVPMYLHLCEKVRPDIDILSMEIMSWEWFKITQSPLFQRVKFPGNVYHPYIPDGYSLKDFLDANINDRPIYIGGDFKSGDSSFQNDYYTISKGLTSQIIPKKDSHKFNTFKIIKTTFSTFPSFHIPNNTEKYPNDSWEHFMMEEMAVSLERAAETLLKEYLSQQNTESFKALELSVEILEKALTYVNDKCWSLKHLGICFDHLRYRVVQNVNNNNQQAQNKASNYSKQLLYFWKKYINQCTHEENTDQDWETIKKVIQLI
The following text describes a protein:
Function:
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Sequence:
MSAKLCFCYFFVSFLSSLFYLLLLPQRQRVLRSINCGIEYQKRAFGDAGKYEMKLSNSSPSIKFVVAKKADSLYPIVSGASIVAKSYTGCLMRLLKTCRGIFDLDILEVRHVILSHAISPNQVLARGSQNIISLDFQHWSDLVGEPAKDAAEVLWESDNLDEDGGGSNNKNRLSNVGFTTSKRSEEIESSGKGRCRFFQARKLEHLTYSSKMCTRYCVNLINILNIY
The following text describes a protein:
Function:
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MRYTNVSILLGMLVIFVSPMVFADDLTPIPEGKPQVVQWFNTHVGPLAQRKGLDPALVAAEAAPRIINVNPKGGEFKTLTDAIKSVPAGNTKRVIIKMAHGEYREKVTIDRNKPFITLMGQPNAMPVITYDGTAAKYGTVDSASLIILSDYFMAVNIVVKNTAPAPDGKTKGAQALSMRISGNFAAFYNCKFYGFQDTICDDTGNHFFKDCYVEGTFDFIFGSGTSMYLGTQLHVVGDGIRVIAAHAGKSAEEKSGYSFVHCKVTGTGGGIYLGRAWMSHPKVVYAYTEMTSVVNPTGWQENKTPAHDKTVFYGEYKCSGPGSHKAKRVPFTQDIDDKEANCFLSLGYIQGSKWLLPPPAL
The following text describes a protein:
Function:
HflC and HflK help govern the stability of phage lambda cII protein, and thereby control the lysogenization frequency of phage lambda. HflKC inhibits the SecY-degrading activity of FtsH, possibly helping quality control of integral membrane proteins.
Miscellaneous:
MISCELLANEOUS: Integration of this protein into the membrane depends on SecA, SecY and SecD but not on SecB or FtsY. HflK is unstable in the absence of HflC.
Subcellular Localization:
Cell inner membrane; Single-pass type II membrane protein.
Sequence:
MAWNQPGNNGQDRDPWGSSKPGGNSEGNGNKGGRDQGPPDLDDIFRKLSKKLGGLGGGKGTGSGGGSSSQGPRPQLGGRVVTIAAAAIVIIWAASGFYTIKEAERGVVTRFGKFSHLVEPGLNWKPTFIDEVKPVNVEAVRELAASGVMLTSDENVVRVEMNVQYRVTNPEKYLYSVTSPDDSLRQATDSALRGVIGKYTMDRILTEGRTVIRSDTQRELEETIRPYDMGITLLDVNFQAARPPEEVKAAFDDAIAARENEQQYIREAEAYTNEVQPRANGQAQRILEEARAYKAQTILEAQGEVARFAKLLPEYKAAPEITRERLYIETMEKVLGNTRKVLVNDKGGNLMVLPLDQMLKGGNAPAAKSDNGASNLLRLPPASSSTTSGASNTSSTSQGDIMDQRRANAQRNDYQRQGE