lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. May be involved in the regulation of some light-responsive genes.
Subcellular Localization:
Nucleus.
Sequence:
MAHSNLFTQQIGGAQGSSAGAGIFRTRERHMLGMPPLEQQIYGGAGRGPEQEPEQLGNPNVMDEVNDMLNYDLIDDLLDFTAAEIESEPFLFDHHTAPKIDEIQVNSTVLPTVDIDPHTLEIPPLENSFRQCDDLNGPGLEWLSNFIDQCCAPLEVGIMMKSADYYSGKASADDGKQISQLPNPSSIPAHQSISNQQRLIDDDKDRDKDNCIVVENGPPLPPPALPSVSPSSSSSSSMNTGSKAPIIISNSSGIFTTLTNRGRAPRTKRRKFIPKHPLNKRPVDFLIPALECDITEERQSKKLKTVHPSSTSVEINLPPTPSSQPHLVPCQKDEETIRNCSHCRAVVTPQWRAGPMGPKTLCNACGVRYKSGRLFPEYRPSASPTFEESRHSNNHKKVVELRGMNANVAKDVKTPASTKGCELLNYINDGCRK
The following text describes a protein:
Function:
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MESPRIGVVRDSMLHRPLLIKPTLGKSKSRGLSYPGPEFVFGTATTVQDGGVQEAISNWHTHTMSTTHRAAERDFIALNREGVKSGLVTAKELHQYRATHDIRRKPLTREGFRRSAPPRLSPDDSFFVSNRPSTPISELIEYKYAQRWLEEQQVRDRVLQAHQHKKAQLGRIQDTRTTLLRKSQPLPEAPSTWKLPRFQKVGAALDTFRDPEARKKAMNAHCSESVSRRGILGQGTYTVD
The following text describes a protein:
Function:
Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis (By similarity).
Sequence:
MGYSLGYIGEHWEEYRAVLYIVLLLPVLIHFLIRRKTQLSNSDKSSEKKDEVKKQREVKRFKRVGKRGKIGSPSSSIRKQNDTIDWKNSPLCVFYSTLGGTAERYAKQVHEELSSLLQRDDIQLLNLDYVDLSEYFVSCPENAIYLVVLPSYEIESSIDYYLSSLQESFSDFRVPKDPLHGLSGYAVFGLGDMENYPGDKFCYQAIQADKWIKKLGARRLAPLGVVNTQLAPTAQIDALLQWTRSVAECLKNGTLLKIGNTDSLSSDVMDVEDMGSMMAKAKAEAALPVGTKEMVSTESPTYKALTKQGYSVVGSHSGVKICRWTKSAMRGRGFCYKYSFYGIRSHLCMEATPSLACANKCTFCWRHGTNPVGTSWRWKVDPPEMILQGILKAHYAKLKLMKGVPGVLPDRYEEASRVRHCALSLVGEPIFYPYINEFVSMLHEREISSFLVTNAQHPEALRNMGMVTQLYVSVDASTKQSLKSVDRPLFKDFWERMLTCLEILREKRQRTVYRMTLVKGFNMEQIKEYTELIRLGVPCFIEVKGVTYSGNSDQSPLTMKNVPYYEEVIDFVKKLIEYIDIHLQDLGVRYEIAAEHAHSCSILVAQTAFKKDGHWHTHIDYPKFFELIRTKKDFGPFDYMASTPDFAMFGNGGFSPEDTRFHRKKKTQTSKPISATISETATISEAAA
The following text describes a protein:
Function:
May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors.
Sequence:
MASFISDFGLMWYLKELNKKEFIKFKEFLIQEILKLKLKQISWTEVKKASREDLANLLLKCYEENQAWDMTFNILQKINRKDLTERATEEIADVVDSSPLGLTDSGNPKLYRDHLKKKLTHDCSKKFNVRIQDFIKEIFIQNDCDTFENLLISKGTEKKPHMVFLQGMAGIGKTMMLKNLMLAWSKGLVFQNKFSYTFYFCCRDVKQLKTASLAELISREWPSPSAPIEEILSQPEKLLFIIDSLEGMECDLTKQESELCDNCMEKQPVSILLSSLLTRKMLPESSFLLSTTPETFEKMEDRILCTDVKTATAFDERSIKIYFHRLFQDKIRAQEAFSLVRENEQLFTICQVPLLCWMVATCLKEEIEKGGDPVSVCRHITSLYTTHILNLFIPQSAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFGEEALRRNGILDSDIPTLLDIGMLGKIREFENYYIFLHPSVQEVCAAIFYLLKSHVDHPSQDVKSIETVLFMFLKKVKTQWIFLGCFIFGLLQKSEQEKLVVFFGRRLSQKIQHKLYQCLETISGNAELQEQIDGMKLFCCLSEIEDEAFLVKVMNCMQQINFVAKNYSDLILAAYCLKHCSTLKKLSFSTQNVLNEKGNQRCMKKLIICWNDMCSVFVRSKDIQVLQIKDTSFNEPAIRILYEYLKYPSFTLNKLVANNVHFFGDNHAFFELIQNCSLQYLDLGCSFLTHSEVKLLCDVLNQAECNIEKLV
The following text describes a protein:
Function:
Required for the localization of ubp5 to the Golgi apparatus. Involved in detoxification of cadmium ion.
Subcellular Localization:
Cytoplasm. Golgi apparatus.
Sequence:
MGGQESKLAFQRGIARLASQPDIPLDDEVWVSLWSVPESCPEVYDFFPPGLIREMRDHAFVNLEKLLLVLTSRLFALKNDKKFPNPETAPASEALNCIRLLTRIIPFLNEKLDLEEWHQKFWWSLRKKRNLPKENSELDLSNFQDDLDFENSISQKNEFSQKSPSVPLSPVSTFPASSISLDASSDVSAADVSVGGSSTIKEIGSIEETFTHEKTLMEELLDTVFRLLFCRGFTLPLSSPEQYAYIIWENGIGTTETQEKTTKELAFNRIEVLRLLLVLISKRLYRSSEVASHTLTYLTCVANKQLILVFLYSLINTTLRLRPDSWKASYSTLVPYNDSSIALSKLTSQILLLFLDHTPHETTVEYFRQRLNLSPGAAIENQYRLYFSRLQLQADYEFLVNELYRLLNAPVSAISAYISIVQKPNIAFPEIILFLWQAILYNKRFRAFLITSPYATEFLTSIQFYALRYREDNEHSGLVRICLFIVHYLSCEKVLCEKLNRNCMNAQSLMSSLGFSVPPMSYAEFLIISSFHISAVKRSPFSSLSPVILLTICNIAPFVENLSFVTCAKLMQLCSSLSSPRFLFRNPRNHLLLEYLLQAISSIVENKFSQNPNLSYSIIRLQQVFLNLNSMKLPAVAQTKSQPLVALNSEGSSDFESKSSDNTSLDGTPLQNTDFKKVATVEDDSPFDELDKFSSPFSSSSSRGGLSHISSRNVSISVPTVLQDVFSDSPLVLSRKLRGKIPENVSSSELIKKCASNPFGKDLEIDSNLFAPSNSWFNSWHSRLELDSILAIISQFSLPVYKKMNEELSTTDEAVKLLANSVLNDVHPRVPNFRYFIWSVPMNNWFQSLVWLYTLSFDEKGLMATPSLFTTSKVYKQHGNIMKVASPENSSNSMENATKSILDKLDLLYLQLPSSVNHDSSLRNK
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (By similarity). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).
Subcellular Localization:
Nucleus, nucleolus. Note=Fibrillar region of the nucleolus.
Sequence:
MEGRGGSRGGAMARGGGRGGFGGGRGGFGGGDRGGRGGGRGGFGGGDRGGRGGFGGGRGGRGGFGGGDRGGRGGARGGRGGARGGKPAAGGKPGAKVIVEKHPRHEGVFIVRGKEESLATLNSVPGESVYGEKRVSVGEGEDKKEYRIWNPFRSKIAAGLHRGVDEIHIKPGSKVLYIGAASGTTISHVSDIVGPTGVVYGIELSHRPGRDLIGMAKKRTNVIPIIEDARHPQKYRMLIGMVDVVFADVAQPNQAQIVAQNSAYFLKNEGHFIISIKASCIDSTAPTEVVVQNEITKLKKEKLRPQHLLKTLDPYERNHSLVIGVYRKFGSSEK
The following text describes a protein:
Function:
Intramembrane glycolipid transporter that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. RFT1 could mediate the translocation of the cytosolically oriented intermediate DolPP-GlcNAc2Man5, produced by ALG11, into the ER lumen where dolichol-linked oligosaccharides assembly continues. However, the intramembrane lipid transporter activity could not be confirmed in vitro.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSEASDRTNLSHTFKYLLATQFLSRGIPFIFNSWIVRHLTEEDYAVYAVQFHLFVTCVLFLSREGFRRACMRADIRFEGASTKDNAATLLKVAWMTFPLGVVITILACVFVFWWQGLHLSDPYAQAILINGYACIAELLAEPLYILSQTLFLLKLRLIVETAATLLRCITMYILIVNLTKMEKGIVFALSQAAYGSCLFLGYWGYFLCAFRSFDLFPFRLGHILDFDKQLRKMCMLFTLQSLQKLVLQEGEKMVLVWLDTPYNQAVYGLVDKLVGSLVVRLVFLPFEESSYATFARSASGQSPHKSKKIGESLTEALKLVLLIGLIFLAFGPSYSYSLVRLLYGQKWSDGEASAALRYYCLYIIVLAMNGTSEAFLHAVATENQLKRSNDSLLVFSVIYVASNYLLIRSAGAVGLILANSLNMILRIIYSAVFIKHFFQESFSFSFYSCLPSGWPMLLLSGVTTLISEKVFLDRKNFWPSFLIHFSIGFTFFCISAFVIYRRERPFISKVIRFRDHLD
The following text describes a protein:
Function:
Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
Subcellular Localization:
Cytoplasm.
Sequence:
MTATDRSIELINAAAQAAADKLAHDIIAYDVSDVLSITDAFLLASAPNDRQVKSIVDEIEERLNKELGAKPVRREGDREARWVLLDYVDIVVHVQHSEERVFYALERLWKDCPELELPADAKETRGKAEEHAKLQAAEEATHTDEDWR
The following text describes a protein:
Function:
A DNA-guided ssDNA endonuclease that may play a role in defense against invading mobile genetic elements. Uses short 5'-phospho-ssDNA sequences as guides (gDNA) to bind complementary target strands, resulting in cleavage of the target DNA (tDNA). Endonucleolytically cleaves DNA in short dsDNA (the gDNA indicates where to cleave on the tDNA). Efficient guide-dependent target DNA cleavage requires a minimal gDNA length of 15 nucleotides (nt) and works up to at least 31 nt. Overexpression decreases plasmid transformation efficiency. Has no appreciable activity with gRNA or on target RNA. Also has guide-independent activity on plasmid DNA called 'chopping'. The cleavage site is 10 nucleotides (nt) downstream of the target residue base-paired with the 5'-end of the gDNA, cleavage is insensitive to adenine methylation. DNA cleavage produces 5'-phosphomonoesters (as it can be ligated by T4 DNA ligase).
Domain:
Has 4 domains; N-terminal, PAZ, Mid and PIWI. The N-terminal, Mid and PIWI domains form a crescent-shaped base with a stalk rising from the end of the N-terminal domain that holds the PAZ domain above the cresent. A groove is present in the center of the crescent closed off by the PAZ domain, in which the putative active sites are found. The PIWI domain assumes an RNase H fold and has the catalytic residues.
Sequence:
MKAKVVINLVKINKKIIPDKIYVYRLFNDPEEELQKEGYSIYRLAYENVGIVIDPENLIIATTKELEYEGEFIPEGEISFSELRNDYQSKLVLRLLKENGIGEYELSKLLRKFRKPKTFGDYKVIPSVEMSVIKHDEDFYLVIHIIHQIQSMKTLWELVNKDPKELEEFLMTHKENLMLKDIASPLKTVYKPCFEEYTKKPKLDHNQEIVKYWYNYHIERYWNTPEAKLEFYRKFGQVDLKQPAILAKFASKIKKNKNYKIYLLPQLVVPTYNAEQLESDVAKEILEYTKLMPEERKELLENILAEVDSDIIDKSLSEIEVEKIAQELENKIRVRDDKGNSVPISQLNVQKSQLLLWTNYSRKYPVILPYEVPEKFRKIREIPMFIILDSGLLADIQNFATNEFRELVKSMYYSLAKKYNSLAKKARSTNEIGLPFLDFRGKEKVITEDLNSDKGIIEVVEQVSSFMKGKELGLAFIAARNKLSSEKFEEIKRRLFNLNVISQVVNEDTLKNKRDKYDRNRLDLFVRHNLLFQVLSKLGVKYYVLDYRFNYDYIIGIDVAPMKRSEGYIGGSAVMFDSQGYIRKIVPIKIGEQRGESVDMNEFFKEMVDKFKEFNIKLDNKKILLLRDGRITNNEEEGLKYISEMFDIEVVTMDVIKNHPVRAFANMKMYFNLGGAIYLIPHKLKQAKGTPIPIKLAKKRIIKNGKVEKQSITRQDVLDIFILTRLNYGSISADMRLPAPVHYAHKFANAIRNEWKIKEEFLAEGFLYFV
The following text describes a protein:
Function:
Component of the ESCRT-II complex, which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation (By similarity).
Subcellular Localization:
Cytoplasm. Endosome membrane; Peripheral membrane protein.
Sequence:
METLFQKTRVINGEPELIQNESIIYKVDNVSIYDGDQKTQYSNGTVMLSTHRVIWVNKDIGLGLLHQLILNIEALTTGLMGIGSSPKILITLTKRSFRLSFHAGRRDDFLKLYRQSLLNKPSQSPSPTSSTSQFINQPNNNNNNYNNNNSYQTPLQPPQYQQQQKEQQQQYNSYNPYQQQSSQSPQQPQQQYNSYNPYQSYVQQQQQQQQQQQQQQQQQQIPQYQQQTSPPPPNYYEHIQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQRQQSPSLYNSYHSTQQPLPPPSYLQHMQQQQQQSPSPSPQYQQTNSNSLPSQPPQPNYNLQNFINTPIISNNSNNNNTNINGFTSNAGIGGIINQMNKKTLENDKLLSESFSDLNILMEKAKDMVTLSEKLKVTLEKKTGTSTSTEEEEEFRSFLLEMGIESPVTKKTAKSKYHDQLSKQLSDWIITKNILKQHKGSGNNEMITLSDLYCIFNRARGIELISPDDLYRACLLFESLDLPLRLRKFDSGVIVVQSKDENDEQIAKQILDIINENGPLSAFDLAKINSISLHLAKDQLLVGVTSEKLGKLCRDETVEGNILYHINIFVD
The following text describes a protein:
Function:
Part of an import route for newly synthesized mitochondrial proteins termed the ER-SURF pathway (ER surface-mediated protein targeting), which retrieves mitochondrial precursor proteins from the ER surface and reroutes them to mitochondria for efficient mitochondrial import. Acts as a quality control factor in the ER, promoting the proteolytic degradation of nonproductive and extramitochondrial precursor proteins in the ER membrane thus removing them from the ER surface.
Miscellaneous:
MISCELLANEOUS: Present with 358 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes to perinuclear ER membranes.
Sequence:
MKLGHREQQFYLWYFIVHIPITIFIDSSVVIPAKWQLGIAQKVVSDHIAKQHDFLLSEKPEWLYWFVVLELVLQLPLFVYFVNKFWNSSELQVNTNSRLKKWLRIYGWNASLTTLICIVVIFKRGYIPYDVLKTSLSMTQKCQLASVYLPTFLIPLRLCFV
The following text describes a protein:
Function:
Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.
Subcellular Localization:
Nucleus.
Sequence:
MQDSLEDYIRISRNCKEGPTQVKKEVLITAQIKKECDAKALQILQFAIEGKMRSDALFKCLPYINQSHYQDIVEERAISKLCGYPLCSKKIPDMPKKQFYISTKNNKVYDITDRKNYCSNFCYRASLHIKGQIDTSPLWLRKYQEKAHYTLLNKSEKGLPGEMIDQGVIKPAVEPYFTSVSSFTQMSLDEAEELELNPQEEEKIKQKKKPRKYQRNAMKTINENEEEEQVESGEKMDEMKESVEILNKENKNTPKIKDKPLAQTKQTNATDVESHIYKCIKEWLTLETFMFVHGEEKVKEKLDSQKLSHYFDALKISQLQVEQQKRYIDICRKLHLRELAEEKFDKAVVGNQALKPIPDYRQLKEESREIDLKVKCFYSGEIHIQEDKNFPSKKEDTTNEEEEQPAVLPLVDVNSQNALRRKIFLNSLNKTVQTLFQTLRISPSLVLSDLQSLVKTFSLKADNIVFKPAIWTYIAIILLKILAVRDENLRKLLDQEASKSQLNTWLSSLPNKTQIVSDTLNILFDIDTFVENYIYARGLIFSVGFSRFKMNLNVNMFSAKKVKLHGMQSDKWTTKDKINQYKGLISLYTRDRKIIELDTNVTRRKLTRLIKDLQRAVYNDRRELDNQIRGDKQKLRNTLAEHRELQLAFQNSQPKKVIEEIKQRNFNRRKVLDRLKYEKKMRSQKLIDLKLEQALLEDRLKYAFLGQIKQEKEAQIITGKLQDAILRKEGASAIYHIYREIIDIMKKDALYFDAIIATVKYDGFSQSKCFLGATKLGQLATEYLDDRRQEYDTLEKIIIKDMTTRKTDIRVLQEHIDRATASIKLLLRKDSDLTTCAKSIRDSASMENLRRDVGQVEKTLVFLKNTTLARSYDTIYPCLEEQLKQKRRLKRLTKKCERDRDIMLNKTNHANLMNSVLKNTMNETTVEYRARKTELKDEVERLRSEKKRYAKLLQIKRTIAANIRIGLRQLLQVSYELSDETKKKPAPSSHPFGVLAERKDKPPEIIEDEIDGSKIVPILVAKFTPLMSHYFGLKHEPKSDEAFRNIESMMQERMILADQSEAPLSEASLLEGLYVEASEQLTREDIKKQSQEIVAANTKNEDLVPLIVVPFNKWKKMQKQQKN
The following text describes a protein:
Function:
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
Subcellular Localization:
Cytoplasm.
Sequence:
MRVHGWVSEVRNLGKVRFIVIRNWNERIQITLKRGMVEDSLFDLTENLTQESVIEVVGKEVKEKIAVGADREVIPERIIVHSLANPQLPLDPNWKVPAQVPTRFDNRPLDLRRPEIQAIFKIESSLLDGMEDWLRRNGFIRVFTPALIGAASESGAEVFKVLYFDKEAYLRQDPQLHRQLTILGGFERIYDLGTNWRAELSRTPRHLSEFRSLAVELAFIENEQDTMRVEEQIIREGIKRVVEERSKELELLNVDLDVPKVPFPELRFPKIYEILEEYGKIIEYGEDYDTESERLLWQYVRENYESDFFFVNRFPFKVKPFYVMKEDDTWARSVDLLYKGLELSSGGQREHRYDVLISQIREKGLDPRSLEWFTKFFAYGAPPHGGFAIGIERLLMKMLELSSVKEASLFPRDPDRILP
The following text describes a protein:
Function:
SNARE required for targeting and fusion of ER-derived transport vesicles with the Golgi complex.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type IV membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Sequence:
MSNTLYNHCTKLFQSIQRSLDELERGVQDESNTISLAGIQGQISASFLSLSRSIDDYDSMVQRELVPAKKKKATIRIQEFRQKHVQLLEKFDELKAHVRDIAQAKNRKELLGRRGYVNSLDSPYGNSTTDAEIVEGPSDLSRQDGLLKEHDFLGRAESQVDEFLERGRMILGDLVEQGSVLKATKTKVLNAANTLGITRHTLSLINRRSKQDKIIFYCGAFLVFVLFYLIYRWLR
The following text describes a protein:
Function:
Probable adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases.
Subcellular Localization:
Cytoplasm.
Domain:
The MATH/TRAF domain binds to receptor cytoplasmic domains.
Sequence:
MKYSIDDLIFSKDIDEDLYCQLCCNLMNESVSCPNGHCLCKGCFHKQIETVKSECPICCIPVTIQTLCKNIYLQKHINNLKVYCPNSFLNNDNNKLILDEKKGCKEILTIEQLKNGKHLKECKFTFVSCEYNEKCGKYRMNEIENHQDQCNYYPTKCFYCKNDFERMNLSNHLLLDCPLVIIGCRYKDGGCNETFPRHELSKHLALEDNHQQYISNIINGHQSLLKSTSKQLKQLRSSCEELETKLINNDYSFNGRWIIKQFSAHFDLFKENPFTNLIISPPIFLTPTKEFSLSLSADTVVNSVNCISVILSKQFQSSSTIKFSFEITNQSQTKSIKKEEKKKFSHLIGSSHSIEFPTSEIYNIHNKFIVNDQLIIKFNIKILSIQDEQQEIEESEENFNNTLITELEE
The following text describes a protein:
Function:
Seminal fluid protease which is required for cleavage and probably also activation of the metalloprotease Semp1. Also required for a number of female post-mating responses independent of Semp1 including egg laying and sperm usage.
Subcellular Localization:
Secreted. Note=Secreted into seminal fluid.
Sequence:
MKRLLFLFLLAGILINNHALQHNETIDLKKLAKIVLPPAYQTRVIGGRVTTNAKLGGYLVAMRYFNNFICGGTLIHELIVLTAAHCFEDRAEKEAWSVDGGISRLSEKGIRRQVKRFIKSAQFKMVTMNMDVAVVLLNRPMVGKNIGTLSLCSTALTPGQTMDVSGWGMTNPDDEGPGHMLRTVSVPVIEKRICREAYRESVSISDSMFCASVLGKKDACTYDSGGPLVYEKQVCGIVSFGIGCASRRYPGVYTDVHYVKPFIVKGIKALLSRSR
The following text describes a protein:
Function:
Catalyzes the dephosphorylation of the riboflavin precursor 5-amino-6-(5-phospho-D-ribitylamino)uracil and of flavin mononucleotide (FMN) in vitro. To a lesser extent, may also catalyze the dephosphorylation of a broad range of substrates such as phosphorylated sugars and triphosphate nucleotides in vitro.
Sequence:
MSVQREDVDIKLIAIDMDGTLLNDEQLISDENRKAIREAEDKGVYVVISTGRTLMTCRELAESLKLSSFLITANGSEIWDSNFNLVERKLLHTDHIQMMWDLRNKHNTNFWASTVNKVWRGEFPENITDHEWLKFGFDIEDDDIRNEVLEELRKNKELEITNSSPTNIEVNALGINKAAALAKVTEKLGFTMENVMAMGDSLNDIAMIKEAGLGVAMGNAQDIVKETADYITDTNIEDGVAKAIRHWVL
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Subcellular Localization:
Secreted.
Sequence:
MSSPFLLLLLLISMAAAGQLRPRFYSETCPDAEFTVREVMRKALIREPRSVASVMRFQFHDCFVNGCDASLLLDETPTMLGEKEALSNINSLRSFEVIDEAKDALEKVCPGVVSCADIIIMAARDAVALTGGPDWEVRLGRLDSLTAKQEDSNEIMPSPRSNASYLIDLFAKFNLSVKDLVALSGSHSIGQARCFSIMFRLYNQSGTGKADPAFEPEYREKLYKLCPSEVDQNVTGDLDATPRVFDNQYFKDLVAGRGFLNSDQTLFTFTPTRMFVKLFSKDQAEFFKAFVEGMLKMGDLQLEQPGEIRRNCRVVNDHRRQWERSSWGKDHSLINGNIFWKMERPPG
The following text describes a protein:
Function:
Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSFHPNAVDAPPSYLHQHQAGSPLYTQNTIRPNANSTDLNSPHKPPILQPWLGLQARLFLAPISIPLISLLFVAARMLSSSNEATDSISSAKGKLLSACSAAEGTASLAASFPHFLAASTNVQLALSVTATVHSAARVFDLSMTAIQKILTYIVNSYKSLFMCFMELLVRGALAVLITAVEFISQAITAATLGIRSAIQESITGVNTLLATAVGAINDVIGVFGQHVNPPHIAVPSLTSLENITLPHEIQDGLVKLNATLPTLQQLKQSMDALIETPFEEMKREVNATLASFQFNHSVFPVPEMQNVTFCDRIDTSPLDELGNALKNVARWGLVALLLIAIVVMLIGVAWEWWKWQKEVKAVERTRSLWLAQRSSAHSDGNDKFCDNILKTENLMSLLTISQHPLISFCSLNYCKRLGIRTRRAQDRCAWLLSFLMHPASLACLFTGVLGLISVLMQAILVHSLSHHYVSSIDTSLAHLSSDIVNLVHDHTRNASVAFSTSANTVILQVEAELNDHVFRWVDTTTSTMNSTLNQFVDGLTETLTSTFGGTPFNAPLQTFVQCILGQKVQGIEKALTWIHENAYVNFSVVPADVLMLRPEQQEAVLRPVREAMLGSRDDQGGGNGVVGHVISRYMEHLHQEKILFTALIGVYAIILLIGLLAVLYATLAERRMHDDDETRKKVSRDESEEKLRSDLQAGPGGAGIARLWSRRPKLNAGCFRAFSHPPVPVSAQNPSSKIDHAARFPSSAHSSRPDPIHVTKDSISYPFQMHHSLNTSPSTRPTQPTPLQQTSNPDRDTVQSLHHASTTHNQTASTRTKEYDSWLCFLASYHDGEATVPAKAPEAVEGAQDRFHRLFGCSLRASPTVATFNHHVSAPAVSSDRAEIEVEDARFRETLDLGSMQDWIGSKSPIPPPAGRGGSHSPRNTADQLPEVQLTRSGGCVGPHSSDSTQETYAFTDSVRLPPGPQPQQKRVVSSQSISFFAW
The following text describes a protein:
Function:
Probably has a role in larval molting.
Subcellular Localization:
Secreted.
Sequence:
MCGPSYCTLLLIAASCYILVCSHAKSLQGTSKLDLGNHISAGSARGSLSPASPALSEARQKRAMGDYKELTDIIDELEENSLAQKASATMQVAAMPPQGQEFDLDTMPPLTYYLLLQKLRQLQSNGEPAYRVRTPRLGRSIDSWRLLDAEGATGMAGGEEAIGGQFMQRMVKKSVPFKPRLGKRAQVCGGD
The following text describes a protein:
Function:
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Required for virulence.
Miscellaneous:
MISCELLANEOUS: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this typical 2-Cys Prx, C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
Sequence:
MSGLKAGDSFPSDVVFSYIPWSEDKGEITACGIPINYNASKEWADKKVILFALPGAFTPVCSARHVPEYIEKLPEIRAKGVDVVAVLAYNDAYVMSAWGKANQVTGDDILFLSDPDARFSKSIGWADEEGRTKRYALVIDHGKITYAALEPAKNHLEFSSAETVLKHL
The following text describes a protein:
Function:
Participates in transcription elongation, termination and antitermination.
Sequence:
MSRAWYVVQTYSQYEKKIEQDIRLLINEGVFGGVVLDVKAPIEKVEEIRNGKKRIRERKIWPGYILIELDLPEVGWKDIIANIIKVQGVINFVGVSKGQRPIPINDEEVKSVFMLTGEIKANKSIFMLYDFEEGERVRIKGGPFDSFEGLISSIDYERKKLKVAVQIFGRSTPVEVDFQHIEKI
The following text describes a protein:
Function:
Catalyzes the amidation of bile acids (BAs) with the amino acids taurine and glycine. More than 95% of the BAs are N-acyl amidates with glycine and taurine. Amidation of BAs in the liver with glycine or taurine prior to their excretion into bile is an important biochemical event in bile acid metabolism. This conjugation (or amidation) plays several important biological roles in that it promotes the secretion of BAs and cholesterol into bile and increases the detergent properties of BAs in the intestine, which facilitates lipid and vitamin absorption. May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.
Subcellular Localization:
Cytoplasm, cytosol. Peroxisome.
Sequence:
MIQLTATPVSALVDEPVHIRATGLIPFQMVSFQASLEDENGDMFYSQAHYRANEFGEVDLNHASSLGGDYMGVHPMGLFWSLKPEKLLTRLLKRDVMNRPFQVQVKLYDLELIVNNKVASAPKASLTLERWYVAPGVTRIKVREGRLRGALFLPPGEGLFPGVIDLFGGLGGLLEFRASLLASRGFASLALAYHNYEDLPRKPEVTDLEYFEEAANFLLRHPKVFGSGVGVVSVCQGVQIGLSMAIYLKQVTATVLINGTNFPFGIPQVYHGQIHQPLPHSAQLISTNALGLLELYRTFETTQVGASQYLFPIEEAQGQFLFIVGEGDKTINSKAHAEQAIGQLKRHGKNNWTLLSYPGAGHLIEPPYSPLCCASTTHDLRLHWGGEVIPHAAAQEHAWKEIQRFLRKHLIPDVTSQL
The following text describes a protein:
Function:
May be involved in wound healing pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALSKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRNSCEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKDDASESTSLSALVTNSDLSLRKS
The following text describes a protein:
Function:
Axoneme-associated protein involved in flagellum motility and central pair positioning.
Subcellular Localization:
Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MYYRTQQKPASVLGANGFTAEVGGRDRVRYFRPPVEVAGVPMRYSGIDTVRFSATAPTTPNLPRTFAETRFDRPTSMAAGLVGPPHHLPSLPRRAGAAPPHPVKAKSVKLPPQRTKRVEKLASTIGTDGKCDAAMQTVFRENEAQTLPYTPNYYIPEGGDPNPQVLGLMELHWNEGLPAGKEEVELIQRLRRRRAVEASLLDETSKEAKMENFCKLYDLEVKEREEREQHFENLRKRRLDQIHEALQERERARDELNRQRLEKVKEQRLANLQRVIEQMESKRVGMGRKALAEQASKAPAAAGRGLYAVDPIETFKRKPDLIQTYARRGTGAVEPQLCTNNGGGSASASPRRDRSRKPLRNYRQYDIQPAMLKYEGGIAELEANKIPKIQQIAPNAFAAPENHAINSLPSLYQRREATRVVEALEYVHAKIHKSDTPAETIRVLELYRATPRPQRPDTPTLELEGDVNEAVEESCTLLQRLLRGRAVQNDFFDGKERCRGLIEELQAASNAKYAERSAEEKQAEAEEKMREAIADSIGNEAQGDIICDTLDYLFHEMTRQQDLLALEALRHEAEAVRAEREAREAELRAQERILHDKEAVQYAAYVRAIEDIVECYSHDLYATVAEECAMEEAIEAECQRLEQLPPPTSNILSDPEVAENLVCDVLDNFVLPAVIDMVRMKPEELDRKAPAAAAAGFRQRSPNEKETKE
The following text describes a protein:
Function:
Functions as an E3 ubiquitin ligase.
Sequence:
MVTNHEEEAYEEEEEDQTTTEGLNPPSNPSSPRARTDDNYNLVESIVAVIQSVKAIGEYRKTQRKECKNLVRRLKLFLPFLDEIRDFETTSFPNSAVVCLKKLKKAVESAKKLLKLCHRGSKIYLALESEAMMVRFHGVYDHISQAVEGMPYEELRISEEEKEQVELLCVQLRRAKRRTDTQDMELTMDLMVALSTNNDRNADIASVERLANKLSLHTCEDLKQETLAIRKLVKERRGLSPESTQQIVNLLNKFKGLAGLEENGICDEPDEPKSLTKSISISVPNEFLCPITLEIMTDPVIVATGQTYERESIQQWLDSNHQTCPKTGQTLEHLSLAPNFALKNLILQWCEKNNFHLPKKEVLTNEETHSTKNEAKILTLVQNLSSSKLDEQRKAVEKIRFLSKESPENRTLIANAGGIQLLVQLLSYPDSKIQEHSVTALLISRSTIGSIGAKENSAAALFSLSMLNENKVKIGTLDGIPPLVELLKTGTMRGKKDAITALFNLCLNPANKTRAIEAGIVGPLLKVLVDEKLEMVNETLSILLILASCAEGRKELGQLQFIETLVSLIREGTPKNKECATAVLLELGSNNRNLILAALQYGVYEHLVEVSKNGTERGQRKAESMIRLMSQAQQIP