lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
Subcellular Localization:
Nucleus.
Sequence:
MMDRGEPTNKHTPPVTTADQTTRPPPQAASSLPRLASSSSGRQAAGQGAFASRPSSSSLPKMTPPVTMPPGGGRDAELFSELWRACAGPLVELPQPGQRVFYFLQGHLEQVLGSVVLNSPVFPPSFSFAFPFLLSVCRLSVQQPSDQKVLADQIKMFQVPYKILCRVVNVELKAEVETEEVYAQITLLPEQDQEYLPSSPDPPLPEVRRPVVHSFSKILTPSDTSTHGGFSVLRRHANECLPPLDMSMPTPTQELICKDILGSEWRFKHIYRGQPRRHLLTTGWSTFVTSKKLVYGDAFVYLRTEEGEQRVGVRHHVQKRTAMPSSVMSSQSMHLGVLASASHALQTKSIFLVYYRPRVSQSQYIVNVNKYFLTSKLRYTVGVRFKMSFEGEEVPVKKFSGTIVGDGALSPQWSCSEWKSKKVQWDDPANCNGPERVSPWEIEPADGAASASTINVPLQSSIRNKRPRETTEDLDLQSLNPTTQEFSLSGMPRQHDKIGDGPSNPNRMIPGNQVIWPGERAAGYSAVGSSSFCQKPLVRESWLEEFNLSRQAMSPTLSEISQKLYQVTRNDARAAPWPVLPAYQAQQPALRLPCNTALHSYRTEEAAPSLPKVTEKSKEPGMVRLFGVNLMKPTSGTATADNAGAGAGETSARVAGPCEESGQVSALSRVTKDHKVVNESPREIQSNQSCIARNRVKVQMHGNAVGRAVDLANLDGYEQLIRELEQMFDIKDIKQNFKVAFADNDGDTMKVGDDPWMEFCRMVKKIVIYPLEEEKMEPHQTPISAAAAAPEQDPKTEP
The following text describes a protein:
Function:
May have a role in embryonic development. It is likely to provide a growth stimulus to target cells in maternal and fetal tissues during the development of the embryo at mid-gestation. May play a role during wound healing and in the hair follicle cycle as a growth factor and/or an angiogenesis factor. May play a role in microvilli formation and cell proliferation of neuroblastoma cells.
Subcellular Localization:
Secreted. Endoplasmic reticulum.
Sequence:
MLPSSIQPCSWILLLLLVNSSLLWKNVASFPMCAMRNGRCFMSFEDTFELAGSLSHNISIEVSELFNEFEKHYSNVSGLRDKSPMRCNTSFLPTPENKEQARLTHYAALLKSGAMILDAWESPLDDLVSELSTIKNVPDIIISKATDIKKKINAVRNGVNALMSTMLQNGDEEKKNPAWFLQSDNEDARIHSLYGMISCLDNDFKKVDIYLNVLKCYMLKIDNC
The following text describes a protein:
Function:
Plays a major role in ovule patterning and in determination of integument identity via its interaction with MADS-box factors. Formation of complex with AG-SEP dimers negatively regulates the carpel identity process and favors the maintenance of ovule identity. BEL1-STM complex maintains the indeterminacy of the inflorescence meristem. Required, with SPL, for cytokinin-induced PIN1 expression in ovules.
Subcellular Localization:
Nucleus.
Domain:
The SR/KY and BELL domains are responsive for the interaction between the TALE/BELL proteins and the TALE/KNOX proteins.
Sequence:
MARDQFYGHNNHHHQEQQHQMINQIQGFDETNQNPTDHHHYNHQIFGSNSNMGMMIDFSKQQQIRMTSGSDHHHHHHQTSGGTDQNQLLEDSSSAMRLCNVNNDFPSEVNDERPPQRPSQGLSLSLSSSNPTSISLQSFELRPQQQQQQGYSGNKSTQHQNLQHTQMMMMMMNSHHQNNNNNNHQHHNHHQFQIGSSKYLSPAQELLSEFCSLGVKESDEEVMMMKHKKKQKGKQQEEWDTSHHSNNDQHDQSATTSSKKHVPPLHSLEFMELQKRKAKLLSMLEELKRRYGHYREQMRVAAAAFEAAVGLGGAEIYTALASRAMSRHFRCLKDGLVGQIQATSQALGEREEDNRAVSIAARGETPRLRLLDQALRQQKSYRQMTLVDAHPWRPQRGLPERAVTTLRAWLFEHFLHPYPSDVDKHILARQTGLSRSQVSNWFINARVRLWKPMIEEMYCEETRSEQMEITNPMMIDTKPDPDQLIRVEPESLSSIVTNPTSKSGHNSTHGTMSLGSTFDFSLYGNQAVTYAGEGGPRGDVSLTLGLQRNDGNGGVSLALSPVTAQGGQLFYGRDHIEEGPVQYSASMLDDDQVQNLPYRNLMGAQLLHDIV
The following text describes a protein:
Function:
Peptide Lv enhances L-type voltage-gated calcium channel (L-VGCC) currents in retinal photoreceptors.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein; [Peptide Lv]: Secreted.
Sequence:
MRLRLLALAAAVLLGPAPEVCGALNVTVSPGPVVDYLEGENATLLCHVSQKRRKDSLLAVRWFFAPDGSQEALMVKMTKLRIIQYYGNFSRTANQQRLRLLEERRGVLYRLSVLTLRPTDQGQYVCKVQEISKHRNKWTAWSNGSSATEMRVISLKAGEDSSFEKKKVTWAFFEDLYVYAVLVCCVGILSVLLFTLVIAWQSVFHKRKSRVRHYLVKCPQNSSGETVTSVTSLAPLQPQKGKRQKKKVDVPPAVPAKAPIATTFHKPKLLKPQRKVALPKITEENLTYAELELIKPHRAAKGVPTSTVYAQILFEENQL
The following text describes a protein:
Function:
Active on adenosine(5')triphospho(5')adenosine (Ap3A), ADP-ribose, NADH, adenosine(5')diphospho(5')adenosine (Ap2A).
Sequence:
MSKSLQKPTILNVETVARSRLFTVESVDLEFSNGVRRVYERMRPTNREAVMIVPIVDDHLILIREYAVGTESYELGFSKGLIDPGESVYEAANRELKEEVGFGANDLTFLKKLSMAPSYFSSKMNIVVAQDLYPESLEGDEPEPLPQVRWPLAHMMDLLEDPDFNEARNVSALFLVREWLKGQGRV
The following text describes a protein:
Function:
Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.
Subcellular Localization:
Endomembrane system.
Sequence:
MGSQGGFGQSKEFLDLIKSIGEARSKAEEDRIVLREIETLKARLSDPNTPKFKLKEYLIRLLYVEMLGHDASFGYIHAVKMTHDDNLLLKRTGYLTVTLFLNEDHDLIILIVNTIQKDLKSDNYLVVCAALNAVCRLINEETIPAVLPQVVELLGHQKEAVRKKAVMALHRFSQRSPGSVSHLLSNFRKRLCDNDPGVMGATLCPLFDLITLDVDKYKDLVVSFVNILKQVAERRLPKSYDYHQMPAPFIQIKLLKILAVLGSGDKKASEQMYTILGDIMRKGDSTSNIGNAILYECICCVSSLHPNAKLLEAAADAISKFLKSDSHNLKYLGIAALSRLIKISPDIAEQHQLAVIDCLEDPDDTLKRKTFELLYKMTKSSNVEVIVDRMIEYMISISDNHYKTEIASRCVELAEQFAPSNQWFIQTMNKVFEHAGDLVNAKVAHNLMRLIAEGFGEDDDTADSQLRSSAVESYLRIMGEPKLPSAFLQVICWVLGEYGTADGKYSASYITGKLCDVAEAHSADDTVKAYAVTALLKIYSFEIAAGRTVDILSECQSLIEELLASNSTDLQQRAYELQAILNVDAHAVEKIMPINSTCDDIEIDKNLAFLDGYVQQSLENGAEPYIPESERSGMLSISSFMTHEDHEPSTHTLRFEAYELPKPSLPPNAPPSSTELVPVTELSYVADIFQPTTSLPSASDSAASELKLRLDGVQKKWGRAHLLLPCPTHHFKQRHCEDSK
The following text describes a protein:
Function:
Possesses E3 ubiquitin-protein ligase in vitro.
Sequence:
MDPEAEEAQLRLEMELAKKAKADMSGLQRSSSLGLDHAGLYPLPLPPGWRSAPTSPLRTPSSPPPLQFPPAWAADVAGTSGSAAPEDDGPARNAGADEATAGSAPKNEDPARAAGADDGPTRSDYAAMMRMALAKFQDDDAAADDEEAASAVMEQAMTGLMDLTYRKAKPPELPYEFATRWPIPIAHDGTLQAEVMRDPVILPSGYSVDQTYQNNQKRQNPWTNTSTFTDHSLPYSLSVPNHLLRDMISAWCLDHSDLSPSTTSDTPSTPLEPSEEEQIQRILKLFSGNSASQREALKLIQLLTKTTKGVQPCLAKYADIIPVLINLRRKYKSSWTQDLEEERLTIILNLTMHRQNREILAGQNELAGAIKKIVKKAGNRGKRTSSLAKVASIVAVLSEFDMFRKRMLDAGGMKMLRGMLKIKDTEVITEAATAILALYADGEGEQPARFHEVPQMLLECHMFTDGILLLLDRLPKSPRVFRKICDQALQLVNIVMAEDASGPVTRKGILSAISLIYEIVERDVGKMNAVKNMEDFIERLRQLSSDRLPMQKMLQVERIIRTLSDAFPAPTVRGRCQEPSGSRLLA
The following text describes a protein:
Function:
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
Sequence:
MGKPCHFAQFDLQPAFLVDLDELGQRYRELVRSVHPDRFADAPEREQRLALERAAQLNEAYQTLKSAPRRALYLLTLSGHELPLEATVQDPEFLLQQMQLREELEELQDSADLAGVATFKRRLKAAQAELEREFAACWDDAQRREEAERLVRRMQFLDKLAQEVRQLEERLDD
The following text describes a protein:
Function:
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
Sequence:
MNILSNSNNNNFNNINSNNYDVLKSNFIILKSITESVKSSYGPNGSSKIIVDENSKSVIISSDGFVILKYFDIKHPIGKLIKQHFLDNIYLLYGGVSTSLIFSCALMENALNLLHRGLDLNSIIKGYQISLKYSLEYLDELDSIKIDLYNNNNNNNNNNINDNDIYKITKNHLLDILNIIIQKGQSSFNNDSNNIDNNDNNSDYKILKNVIVDAIIQYPDFIDLETRLKCINFSTDLLYENFNNCIQNQENINIDNNQGIRKYKSEYCLVEAALIENGYLFDLPKPCSFIKELKEEEPKVIFLNCSLTREDSNMQIQVEFDNPEKLLAWKIDEENYLKSIITDIATRLKVNTIICTGDIDPIILDSINEFNILAFKFIPLNYFKKLVNNNIYINNNNNNNNNNISNNKIIYNLDDLKLINENNISNNFEKITIYNNNNNDKKNNNFLKYYFKIKNYIQNNIQNQNYKMEYKMEYKIEQKTILILTETTIYAQQLKKYCEDLLMSLNLLGRDSESSGNDINNKDFLDFFGFFQSDAIKKNYLKKRFFAKIFIEGMGTAEKTIARKLLEKSTQESSQLKYPMEAFSLSLNSISIFLDSSDDVKSKKNSEINDIIGK
The following text describes a protein:
Function:
Member of the three-protein two-component system HK1/HK2/TcrA.
Miscellaneous:
MISCELLANEOUS: Was identified as a high-confidence drug target.
Subcellular Localization:
Cytoplasm.
Sequence:
MADETTMRAGRGPGRACGRVSGVRILVVEDEPKMTALLARALTEEGHTVDTVADGRHAVAAVDGGDYDAVVLDVMLPGIDGFEVCARLRRQRVWTPVLMLTARGAVTDRIAGLDGGADDYLTKPFNLDELFARLRALSRRGPIPRPPTLEAGDLRLDPSEHRVWRADTEIRLSHKEFTLLEALIRRPGIVHTRAQLLERCWDAAYEARSNIVDVYIRYLRDKIDRPFGVTSLETIRGAGYRLRKDGGRHALPR
The following text describes a protein:
Function:
Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence. Has transcription repressor activity in vitro (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSAQSVEEDSILIIPTPDEEEKILRVKLEEDPDGEEGSSIPWNHLPDPEIFRQRFRQFGYQDSPGPREAVSQLRELCRLWLRPETHTKEQILELVVLEQFVAILPKELQTWVRDHHPENGEEAVTVLEDLESELDDPGQPVSLRRRKREVLVEDMVSQEEAQGLPSSELDAVENQLKWASWELHSLRHCDDDGRTENGALAPKQELPSAVESHEVPGTLNMGVPQIFKYGETCFPKGRFERKRNPSRKKQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSILVQHQRVHTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRHXXXHNAXKLLNVVKV
The following text describes a protein:
Function:
Choline transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
VESRRTCTDVLFLLLLVCAWIAMTGVGLAATGLIKSEVIKKGDPRRLINGLDYHANICGVTNYQTPLGADVINLPKAYPLPSGYFVCVERCPSVTNYDEFHCEYETVDITNTKKSLQIAHTSQKQCMPYIKSTSFLSYCIPDIPNVTTSNNETHTEISITMEDQINSQSDFFDKLMTDVYNVRYVIFYFGCGMAMVLGIVFLVVIQLPGFLSLLVWTMIIAVDASLIGAGWYTKETSLKWASSETRGGNEAVALFYASYVLYGLAVLWVMIICYIRRRIVLAIYCVKESARAISAMPVMTLFPVAQVLGLVAFTVVWGIYMAFLASSGDVTGSYGCFLYKELTYSTNTKYAALYMLFMWFWTSQFLVAVGQLVVAVSVSLWYFSRDRSQIGNTTFCRVLYLVSFHHLGTAAFGSLVIAIVKTIGTILTYVQKRLSKSQLRLAVLLLKVLHNLMWCIEKCLKFINKQAYCQTAIFSYSFCKAARMGFFLILRNALRISAVSIVSRIVLFINKTFITVASTVAGYYYLEMHFGDELNLLMMPTLLIGLVAYAVSEMFDEVFGMSISTLLQCFIADEEMFDDS
The following text describes a protein:
Function:
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
Subcellular Localization:
Nucleus.
Sequence:
MSEKKQTVDLGLLEEDDEFEEFPAEDWTGLDEDEDAHVWEDNWDDDNVEDDFSNQLRAELEKHGYKMETS
The following text describes a protein:
Function:
This protein acts as a DNA primase generating di- to pentaribonucleotides; the predominant product being the dimer pppApG. It complexes specifically to the P4 origin of replication (ori) and its cis replication region (crr). It also acts as a DNA helicase.
Sequence:
MKMNVTATVSHALGHWPRILPALGIQVLKNRHQPCPVCGGSDRFRFDDREGRGTWYCNQCGAGDGLKLVEKVFGVSPSDAAAKVAAVTGSLPPADPAVTTAAVDETDAARKNAAALAQTLMAKTRTGTGNAYLTRKGFPGRECRMLTGTHRAGGVSWRAGDLVVPLYDDSGELVNLQLISADGRKRTLKGGQVRGTCHTLEGQNQAGKRLWIAEGYATALTVHHLTGETVMVALSSVNLLSLASLARQKHPACQIVLAADRDLSGDGQKKAAAAADACEGVVALPPVFGDWNDAFTQYGGEATRKAIYDAIRPPAESPFDTMSEAEFSAMSTSEKAMRIYEHYGEALAVDANGQLLSRYENGVWKVLPPQDFARDVAGLFQRLRAPFSSGKVASVVDTLKLIIPQQEAPSRRLIGFRNGVLDTQNGTFHPHSPSHWMRTLCDVDFTPPVDGETLETHAPAFWRWLDRAAGGRAEKRDVILAALFMVLANRYDWQLFLEVTGPGGSGKSIMAEIATLLAGEDNATSATIETLESPRERAALTGFSLIRLPDQEKWSGDGAGLKAITGGDAVSVDPKYRDAYSTHIPAVILAVNNNPMRFTDRSGGVSRRRVIIHFPEQIAPQERDPQLKDKITRELAVIVRHLMQKFSDPMLARSLLQSQQNSDEALNIKRDADPTFDFIGYLETLPQTSGMYMGNASIIPRNYRKYLYHAYLAYMEANGYRNVLSLKMFGLGLPVMLKEYGLNYEKRHTKQGIQTNLTLKEESYGDWLPKCDDPTTA
The following text describes a protein:
Function:
Required for assembly and stability of the TOM complex. Positive regulator of PRKN translocation to damaged mitochondria. Acts probably by stabilizing PINK1 on the outer membrane of depolarized mitochondria.
Subcellular Localization:
Mitochondrion outer membrane; Single-pass membrane protein.
Sequence:
MVKLSKEAKQRLQQLFKGSQFAIRWGFIPLVIYLGFKRGADPGMPEPTVLSLLWG
The following text describes a protein:
Function:
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. Important for bud site selection.
Miscellaneous:
MISCELLANEOUS: Present with 3020 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus. Chromosome, telomere.
Domain:
This protein is considered an atypical serine/threonine kinase, because it lacks the conventional structural elements necessary for the substrate recognition as well as a lysine residue that in all other serine/threonine kinases participates in the catalytic event. BUD32 has protein kinase activity in vitro, but in the context of the EKC/KEOPS complex, the catalytic subunit KAE1 switches the activity of BUD32 from kinase into ATPase (By similarity).
Sequence:
MTQEFIDKVSSYLTPDVDIAPISQGAEAIVFTTTTHPYLPRAKDSHQKYIIKYRPPKRYRHPQIDQALTKHRTLNESRLLAKLYLIPGLCVPQLIACDPYNGFIWLEFLGEDLPGGHGFSNLKNFLWMHDQDPYSDLVATTLRKVGRQIGLLHWNDYCHGDLTSSNIVLVRDGARWTPHLIDFGLGSVSNLVEDKGVDLYVLERAILSTHSKHAEKYNAWIMEGFEEVYREQGAKGAKKLKEVTKRFEEVRLRGRKRSMLG
The following text describes a protein:
Function:
Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.
Subcellular Localization:
Nucleus.
Sequence:
MFGDQAFKLATEAKACLNLDSVKPYNDELIRALILETKQLHAHLTTLLSTLEDSAQHTAVEVAGLQSQLLMLHLIISYNKRSLLIYHNVRLDLVMSHLSRHSFSLRILFSHHPALRTALSAIEHDHLRRYSDLIHRTKLSYLNLSPSLKLDIADTQVFEPLPTDPLVTVKVNRDLNDIWLTSSQSAPTSMRKDQTLTINRADVRPLIARGWLTVLDDPR
The following text describes a protein:
Function:
Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
Subcellular Localization:
Nucleus.
Sequence:
MALKDYAIEKEKVKKFLQEFYYDDELGKKQFKYGTQLVHLAHREQVALYVDLDDVAEDDPELVDSICENAKRYSRLFADVVQELLPEYKEKEVVNKDVLDVYIEHRLMMEQRSRDPGAVRNPQNQYPSELMRRFELYFQGPSSSKPRVIREVRADSVGKLLTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKIQEHSDQVPVGNIPRSITVVLEGENTRIAQPGDHVSVTGIFLPVLRTGFQQMAQGLLSETYLEAHRVVKMTKSEDDVSGAGELSAEELKQIADVIFATVRELVSGGRSVRFSEAEQRCISRGFTPAQFQAALDEYEELNVWQVNTSRTRITFV
The following text describes a protein:
Function:
Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway.
Miscellaneous:
MISCELLANEOUS: Present with 782 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MRDIVFVSPQLYLSSQEGWKSDSAKSGFIPILKNDLQRFQDSLKHIVDARNSLSETLLNSNDDGSIHNSDQNTGLNKDKEASIADNNSANKCATSSSRYQELKQFLPISLDQQIHTVSLQGVSSSFSRGQIESLLDHCLNLALTETQSNSALKVEAWSSFSSFLDTQDIFIRFSKVDEDEAFVNTLNYCKALFAFIRKLHEDFKIELHLDLNTKEYVEDRTGTIPSVKPEKASEFYSVFKNIEDQTDERNSKKEQLDDSSTQYKVDTNTLSDLPSDALDQLCKDIIEFRTKVVSIEKEKKMKSTYEESRRQRHQMQKVFDQIRKNHSGAKGSANTEEEDTNMEDEDEEDDTEDDLALEKRKEERDLEESNRRYEDMLHQLHSNTEPKIKSIRADIMSAENYEEHLEKNRSLYLKELLHLANDVHYDHHRSFKEQEERRDEEDRAKNGNAKELAPIQLSDGKAISAGKAAAITLPEGTVKSENYNADKNVSESSEHVKIKFDFKKAIDHSVESSSEDEGYRESELPPTKPSERSAAEDRLPFTADELNIRLTNLKESRYVDELVREFLGVYEDELVEYILENIRVNQSKQALLNELRETFDEDGETIADRLWSRKEFRLGT
The following text describes a protein:
Function:
Subunit of heteromeric glycine-gated chloride channels. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents.
Subcellular Localization:
Cell projection, dendrite. Cytoplasm. Postsynaptic cell membrane; Multi-pass membrane protein.
Sequence:
MPFSVSLVLSRMKVIKLTFLILVFAIWMEEGFTKEKSSKKGKGKRKQHLCPSQLSSEDLARVPANSTSNILNRLLVSYDPRIRPNFKGIPVDDKVNIFINSFGSIQETTMDYRVNIFLRQRWNDPRLRLPTDFKSDALTVDPKMFKCLWKPDLFFANEKNANFHDVTQENILLFIYRNGDVLLSMRLSVTLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQMEQIALPQFDIKQEDIEYGNCTKYYKGTGYYTCVEVIFTLRRQVGFYMMGVYGPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLSSECTSLASELPKVSYVKAIDIWLIACLLFGFASLVEYAVVQVMLNSPKRIEAEKAKMASKEQAEGKAPAKKNTVNGTGGTPIHVSTLQVAETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVSSALGKSQAKNNKKPPPPKPVIPSEAKRIDLYARALFPFSFLFFNVIYWSIYL
The following text describes a protein:
Function:
Catalyzes the hydrolysis of sphingomyelin producing a ceramide (N-acyl-sphingoid base) and a phosphocholine (By similarity). C.elegans contain specific sphingoid bases, which are unique or different in structure compared to the sphingoid bases found in other animals. Two examples of these distinctive compounds are: 15-methylhexadecasphinganine and 15-methylhexadecasphing-4-enine.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MEPSSEQESQESQKVDMEPVFRRESFAALRRNNVAARQLRVVTLNAWCLPQPWPIGSTDRVHRLNKIGQYMIDELYDIVGLQELWSYYDFVRLSEQVSSVYPYFHYFHSGFTGSGVCVFSRHPIVSTLTNRYSLNGFAHHIHRGDWFGGKVVGLTEIEIDGDLRVNFYTTHLHAEYDRENDLYLPHRTAQAFELAQFVRHTARGADVVIVTGDLNMEPCDLGFRLILSHAKLFDAWRMSHEVENEDSEGELLKFRGIAKGGTCDRPDNCYTKRALKNVDDSKRIDYMLFKSGRCNVKLEECEITLNQIPGEDLNYSDHVGLRARFTIDDRFRHEKSVNTWEPNRPLLIEAIGLVAGGERRARTDRIFFFILAVICLILILGSLFFEVFPMGFAVLRFALTVVGVFFVWQGLIGLTLERKALKAAKQAIQQILNN
The following text describes a protein:
Function:
This protein is postulated to act both as terminal energy acceptor (by its phycobilin-like domains) and as a linker polypeptide (by its repeats and arms) that stabilizes the phycobilisome core architecture. Has intrinsic bilin lyase activity (By similarity).
Subcellular Localization:
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Anchors the phycobilisome perpendicularly to the cytoplasmic surface of the thylakoid membrane.
Sequence:
MSVKASGGSSLARPQLYQTVPVSAISQAEQQDRFLEGSELNELTAYFQSGALRLEIAETLTQNADLIVSRAANRIFTGGSPLSYLEKPVERQPALVGASSDSRNGSVTYAESNGSGGLFGGLRSVFSSTGPIPPGFRPINIARYGPSNMQKSLRDMSWFLRYTTYAIVAGDPNIIVVNTRGLKEVIENACSIDATIVAIQEMRAASADYFRNNAQAKEIVLQYFDILLSEFKAPTPANKVRQGPSNDIQGLELPQSYFNAAAKRQKYAMKPGLSALEKNAVIKAAYRQIFERDITKAYSQSISYLESQVRNGDISMKEFVRRLAKSPLYRKQFFEPFINSRALELAFRHILGRGPSSREEVQKYFSIVSSGGLPALVDALVDSQEYADYFGEETVPYLRGLGVEAQECRNWGMQQDLFSYSAPFRKVPQFITTFAQYDRPLPDQHVYGSGNDPLEIQFGAIFPKETRNPSKRPAPFNKDTKRILIHRGPAVNNQVGNPSAVGEFPGSLGAKVFRLNGGLPGAKVGKNTGTSVKFGESSTQALIRAAYRQVFGRDLYEGQRLSVAEIQLENGDISVREFIKRLAKSELFLKLYWAPHYVCKAIEYMHRRLLGRPTYGRQEMNQYFDIASKQGFYAVVEAMIDSKEYSDAFGEDTVPYERYLTPGGLQMRSARVGSLREDIGQRVDKEVTPRFVELGQVSAIRTEPEIAYRSNQGVTRQRQQTKVFKLVSTYDKVAVKNAIRAAYRQVFERDLEPYIINSEFTALESKLSNNEINVKEFIEGLGTSELYMKEFYAPYPNTKVIEMGTKHFLGRAPLNQKEIQQYNQILASQGLKAFIGAMVNGMEYLQTFGEDTVPYRRFPTLPAANFPNTERLYNKLTKQDKELVVPSFTPVVKVGG
The following text describes a protein:
Function:
Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol. Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways. Also has a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids. Also able to degrade bis(monoacylglycero)phosphate (BMP) and constitutes the major enzyme for BMP catabolism. BMP, also known as lysobisphosphatidic acid, is enriched in late endosomes and lysosomes and plays a key role in the formation of intraluminal vesicles and in lipid sorting.
Subcellular Localization:
Late endosome membrane; Single-pass type II membrane protein. Lysosome membrane; Single-pass type II membrane protein. Mitochondrion membrane; Single-pass type II membrane protein.
Sequence:
MKSGYSSYFSKTPKKTIRGTAVFMIHGVGGKFKVWSPQITFLNNYGFTVIALNLIGHGGSSKPRDQAAYTFEKMSKDVFAIFDKFMMQKNVIVGHSYGCCFAALLARQKPDYIHGLIMISGGAPIPLGPQLGIFGLPLCCLQCIKCILYREFLSRSFHKPNRNNLCHLTAITVPIFVLKNTLNGQRWDEGGVNFYSLIASPTLLIQGKKDRLISVEEVYFMKNTIKTSSLVLMENVGHMVMLESPDDLNSLIAYFMEEFLDKQSLSMSTESS
The following text describes a protein:
Function:
Mediates the regulation of male germ cell division by DUO1.
Subcellular Localization:
Nucleus.
Sequence:
MSNTSNSDPNSDIPFASSNVTLPSYNQNPRRKRTKLTNNEVGSSSSSPRPKPVTQPDPDASQIARPCTECGKQFGSLKALFGHMRCHPERQWRGINPPSNFKRRINSNAASSSSSWDPSEEEHNIASCLLMMANGDVPTRSSEVEERFECDGCKKVFGSHQALGGHRATHKDVKGCFANKNITEDPPPPPPQEIVDQDKGKSVKLVSGMNHRCNICSRVFSSGQALGGHMRCHWEKDQEENQVRGIDLNVPAATSSDTTLGCSLDLRLGL
The following text describes a protein:
Function:
Plays a role in the reduction of telomerase activity during differentiation of embryonic stem cells by binding to the core promoter of TERT and controlling its down-regulation.
Subcellular Localization:
Nucleus speckle.
Sequence:
MYPSWGNFSVPPPPSFAGPGPRKPVGGNHAGQPAGFGGFEAPSSGSLFSSLQEQHRQQMQQLQMLHQKQLQSVLHHGNNASQFGSGHSGGYPGQSWHSEGSKEDDGTQAFYNQEGAPTSTGPPAPTQGPQQPPADPQPGPPPPQTQTPNPPDSNGAFKGTKAGIQDCSAAEDKSLPLQEQQQLWYKQHLKNLQKLRQEKARQSQKDGDAPPPPPHPASSHTTPPPPPSDPPKSAPPPPPPSDEPPAPPLPVEVRRENVGNPPALTDTPEVPKDPEEAARLQQLQAAAAQWQQVQQQRVGLQYQALMQQHEKLQQVLERYQTLIQQPPNLQSMSADLQLRHYEMQQQQFNSLFQDWNVSFASWYEQFQTYPHKNQLQDYERQWKQWQEQMAATSAHLQERVASLTAVVPFASIQYNSPMVGQFNQYPGQDMQMQQHAVNLGVQPPAAAVGPSPPAQQPPGFGAHPEAPAEPPLQGGVSTGIGVTTSGPSGQPQSFTGIGGPSPRMKRFDQPPQGFDGSSRVDPPQQRFDRPPPFDQPHHRFDGPPRFDQPRQRFDAPPRFDHPRQRFEGPPRFDQPRSRFDGPPRFEPPRQRFDGPPRFVQPRPSLQQHRPLGPSPRFESPPVTQKQEAAQPEFTQVSQESTGTSAKSSTMKNVPQRPVEKNKGYKENYKTNMDDILDDSLLGTDGFFVQDDPIPQTLQDGPEPEKTDDNSLASNDGKPQPGDAKLSLAPEAPGQNLLKPEGALKNEPLQTPRPPEIKPDPKVSGNVHTGTEPPKPIPGRGRGQPLMRGRGKIIGGELRASKPAVEETEETFYDQMHPEEGMDMSEEQEDYNWQSSYEEFGGEETEGPPEDAWGPEEQYFQDEEYFETPMGPHTGRGRPPLLRGRPPLLRGPPVGRGFPPRGRPPLIRGGPPMGRGGPYMQRGGPPMGRGGPHMIRGGPPMGRGGPHMLRGGPPMGRGGPPMGRGGPPMGRGGPPVGRGGPPIGRGEPFDRHWEDIESAEYAEEEGDPYWEEWRPPMRGMRPPFPPSRGRPPRGHPGFMPPIRGRPPHRPMEPDLDPDAAASDPSIYHGRDPYGPSMNPEAGRGRRLLPPHEMGDALGEGLYGEGEQELNWPPPHARGPPMPPHDLIERGGMRRRPMGRGIGRGAWRPGAASEEYEEEYKKGFAVDYAHGEEGYRRHLAQDYPPEQFDDKLFDSQWDSEHHLEREYPPRMPPPEHLRERFRRPEAERAHPYPCDEPGRGELRIREYRDEMAYRQDEPPQAPSQEWDRPSRLPPPPGRDYPFDYPERRLRYEEPRASSPPSAAHAPDLPEGSAESQAGGGANVLALSQRQHEIILKAAQELKQIRELQEANPLSTDPQPAASKALPELPAGLLGLEIPPDVRNVLKGMTTAAAPPASESWESKPAALNYQPSLSAASVIPKTVDYGHGHEPGATVERMSYGERIILRPDPPPSDRGYEKELLGLRDPYSRDPYYDRRSDPYLERREYSRDREMFREKPEYERERFEREGYPPRERDDRSPLRLAYRDRSGSRDPEDHYGRPGYDRLPFERAGLERIGPERYSSPYTVERRAYPEDRGPPAAAPLPPPPRVEKKPEIKNIDDILKPPGRLSRPDRIVIIMRGLPGSGKSHVAKLIRDKEVESGGAPPRVLVLDDYFMTEVERIEKDPDSGKKVKTKVMEYEYEPEMEDTYRSSMLKTFKKTLDDGFFPFIILDTINDKVKHFDQFWSAAKTKGFEVYVAEITADTQTCAKRNLHGRTHKDITKMSGNWEPSPRHMVRLDVRSLLQDAAIEEVEMEDFNPDEESMEPKREEEEESDLGYIPKSKWEMDTSEAKLDKLDGLVSGGKRKREGDHVSGLVDFLQLPDDYATRMSEPGKKRVRWADLEEQKDADRKRAIGFVVGQTDWEKITDESGQLAQRALNRTKYF
The following text describes a protein:
Function:
Involved in the positive regulation of tracheary element (TE) differentiation. Involved in a positive feedback loop that maintains or promotes NAC030/VND7 expression that regulates TE differentiation-related genes. Functions in the initiation and emergence of lateral roots, in conjunction with LBD16, downstream of ARF7 and ARF19. Transcriptional activator that directly regulates EXPA14, a gene encoding a cell wall-loosening factor that promotes lateral root emergence. Activates EXPA14 by directly binding to a specific region of its promoter. Transcriptional activator that directly regulates EXPA17, a gene encoding a cell wall-loosening factor that promotes lateral root emergence. Acts downstream of the auxin influx carriers AUX1 and LAX1 in the regulation of lateral root initiation and development.
Miscellaneous:
MISCELLANEOUS: Plants over-expressing LBD18 have a dwarf and bushy phenotype, with short petioles, curled downward leaves, ectopic shoots from the adaxial side of cotyledons, shrunken root tips and disorganized columella cells.
Subcellular Localization:
Nucleus.
Sequence:
MSGGGNTITAVGGGGGGCGGGGSSGGGGSSGGGGGGPCGACKFLRRKCVPGCIFAPYFDSEQGSAYFAAVHKVFGASNVSKLLLHIPVHRRSDAVVTICYEAQARIRDPIYGCVAHIFALQQQVVNLQAEVSYLQAHLASLELPQPQTRPQPMPQPQPLFFTPPPPLAITDLPASVSPLPSTYDLASIFDQTTSSSAWATQQRRFIDPRHQYGVSSSSSSVAVGLGGENSHDLQALAHELLHRQGSPPPAATDHSPSRTMSR