Query: What region is Nanjing in?
Context: Nanjing ( listen; Chinese: 南京, "Southern Capital") is the city situated in the heartland of lower Yangtze River region in China, which has long been a major centre of culture, education, research, politics, economy, transport networks and tourism. It is the capital city of Jiangsu province of People's Republic of China and the second largest city in East China, with a total population of 8,216,100, and legally the capital of Republic of China which lost the mainland during the civil war.