Query: What siege occurred in 1565?
Context: In southern Europe, a Catholic coalition led by Philip II of Spain won a victory over the Ottoman fleet at the Battle of Lepanto (1571). It was a startling, if mostly symbolic, blow to the image of Ottoman invincibility, an image which the victory of the Knights of Malta against the Ottoman invaders in the 1565 Siege of Malta had recently set about eroding. The battle was far more damaging to the Ottoman navy in sapping experienced manpower than the loss of ships, which were rapidly replaced.