page_title: Neonatal diabetes
section_title: Mechanism
hierarchical_section_title: Neonatal diabetes / Mechanism
caption_attribution_description: Português: Monitores de Glicemia
context_page_description: Neonatal diabetes mellitus is a disease that affects an infant and their body's ability to produce or use insulin. NDM is a monogenic form of diabetes that occurs in the first 6 months of life. Infants do not produce enough insulin, leading to an increase in glucose accumulation. It is a rare disease, occurring in only one in 100,000 to 500,000 live births. NDM can be mistaken for the much more common type 1 diabetes, but type 1 diabetes usually occurs later than the first 6 months of life. There are two types of NDM: permanent neonatal diabetes mellitus is a lifelong condition. Transient neonatal diabetes mellitus is diabetes that disappears during the infant stage but may reappear later in life.
  Specific genes that can cause NDM have been identified. The onset of NDM can be caused by abnormal pancreatic development, beta cell dysfunction or accelerated beta cell dysfunction. Individuals with monogenic diabetes can pass it on to their children or future generations. Each gene associated with NDM has a different inheritance pattern.
caption: Neonatal Diabetes Mellitus (NDM)
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