page_title: Fructose-bisphosphate aldolase
hierarchical_section_title: Fructose-bisphosphate aldolase
caption_attribution_description: English: Fructose 1,6-bisphosphate aldolase homo8mer + 6 SO4 (yellow-red), Human
context_page_description: Fructose-bisphosphate aldolase, often just aldolase, is an enzyme catalyzing a reversible reaction that splits the aldol, fructose 1,6-bisphosphate, into the triose phosphates dihydroxyacetone phosphate and glyceraldehyde 3-phosphate. Aldolase can also produce DHAP from other-ketose 1-phosphates such as fructose 1-phosphate and sedoheptulose 1,7-bisphosphate. Gluconeogenesis and the Calvin cycle, which are anabolic pathways, use the reverse reaction. Glycolysis, a catabolic pathway, uses the forward reaction. Aldolase is divided into two classes by mechanism.
  The word aldolase also refers, more generally, to an enzyme that performs an aldol reaction or its reverse, such as Sialic acid aldolase, which forms sialic acid. See the list of aldolases.
context_section_description: Fructose-bisphosphate aldolase (EC 4.1.2.13), often just aldolase, is an enzyme catalyzing a reversible reaction that splits the aldol, fructose 1,6-bisphosphate, into the triose phosphates dihydroxyacetone phosphate (DHAP) and glyceraldehyde 3-phosphate (G3P). Aldolase can also produce DHAP from other (3S,4R)-ketose 1-phosphates such as fructose 1-phosphate and sedoheptulose 1,7-bisphosphate. Gluconeogenesis and the Calvin cycle, which are anabolic pathways,  use the reverse reaction. Glycolysis, a catabolic pathway, uses the forward reaction.  Aldolase is divided into two classes by mechanism.
  The word aldolase also refers, more generally, to an enzyme that performs an aldol reaction (creating an aldol) or its reverse (cleaving an aldol), such as Sialic acid aldolase, which forms sialic acid. See the list of aldolases.
caption: Fructose-bisphosphate aldolase octamer, Human
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