page_title: Arfaptin
hierarchical_section_title: Arfaptin
caption_attribution_description: English: Cartoon representation of the molecular structure of protein registered with 1i4d code. Deutsch: Grafik des Molekularstruktur von jenem Protein, das mit 1i4d code registriert ist. Plattdüütsch: Grafik, de de Molekularstruktur von dat Protein wiest, dat mit’n Kood 1i4d registreert is.
context_page_description: In molecular biology, the arfaptin domain is a protein domain which interacts with ARF1, a small GTPase involved in vesicle budding at the Golgi complex and immature secretory granules. The structure of arfaptin shows that upon binding to a small GTPase, arfaptin forms an elongated, crescent-shaped dimer of three-helix coiled-coils. The N-terminal region of ICA69 is similar to arfaptin.
context_section_description: In molecular biology, the arfaptin domain is a protein domain which interacts with ARF1, a small GTPase involved in vesicle budding at the Golgi complex and immature secretory granules. The structure of arfaptin shows that upon binding to a small GTPase, arfaptin forms an elongated, crescent-shaped dimer of three-helix coiled-coils. The N-terminal region of ICA69 is similar to arfaptin.
caption: crystal structure analysis of rac1-gdp complexed with arfaptin (p21)
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