page_title: Mir-196 microRNA precursor family
hierarchical_section_title: Mir-196 microRNA precursor family
caption_attribution_description: English: Image has been uploaded to the Commons as part of the Molecular and Cellular Biology WikiProject in collaboration with the public-domain database Rfam. Here is the link to the discussion.
context_page_description: miR-196 is a non-coding RNA called a microRNA that has been shown to be expressed in humans and mice.
  miR-196 appears to be a vertebrate specific microRNA and has now been predicted or experimentally confirmed in a wide range of vertebrate species. In many species the miRNA appears to be expressed from intergenic regions in HOX gene clusters. The hairpin precursors are predicted based on base pairing and cross-species conservation—their extents are not known. In this case the mature sequence is excised from the 5' arm of the hairpin.
  It has been suggested that a rare SNP that overlaps has-mir-196a2 has been found to be associated with non-small cell lung carcinoma.
context_section_description: miR-196 is a non-coding RNA called a microRNA that has been shown to be expressed in humans (MI0000238, MI0000279) and mice (MI0000552, MI0000553). 
  miR-196 appears to be a vertebrate specific microRNA and has now been predicted or experimentally confirmed in a wide range of vertebrate species (MIPF0000031). In many species the miRNA appears to be expressed from intergenic regions in HOX gene clusters. The hairpin precursors are predicted based on base pairing and cross-species conservation—their extents are not known.  In this case the mature sequence is excised from the 5' arm of the hairpin.
  It has been suggested that a rare SNP (rs11614913) that overlaps has-mir-196a2 has been found to be associated with non-small cell lung carcinoma.
caption: Predicted secondary structure and sequence conservation of mir-196
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