page_title: CopA-like RNA
hierarchical_section_title: CopA-like RNA
caption_attribution_description: English: Image has been uploaded to the Commons as part of the Molecular and Cellular Biology WikiProject in collaboration with the public-domain database Rfam. Here is the link to the discussion.
context_page_description: CopA-like RNA is a family of non-coding RNAs found on the R1 plasmid.
  In several groups of bacterial plasmids, antisense RNAs regulate copy number through inhibition of replication initiator protein synthesis. These RNAs are characterised by a long hairpin structure interrupted by several unpaired nucleotides or bulged loops. In plasmid R1, the inhibitory complex between the antisense RNA and its target mRNA is characterised by a four-way junction structure and a side-by-side helical alignment.
context_section_description: CopA-like RNA is a family of non-coding RNAs found on the R1 plasmid.
  In several groups of bacterial plasmids, antisense RNAs regulate copy number through inhibition of replication initiator protein synthesis. These RNAs are characterised by a long hairpin structure interrupted by several unpaired nucleotides or bulged loops. In plasmid R1, the inhibitory complex between the antisense RNA (CopA) and its target mRNA (CopT) is characterised by a four-way junction structure and a side-by-side helical alignment.
caption: Predicted secondary structure and sequence conservation of CopA
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