page_title: Phosphoramidite
hierarchical_section_title: Phosphoramidite
caption_attribution_description: English: Phosphoramidite Structure
context_page_description: A phosphoramidite (RO)₂PNR₂ is a monoamide of a phosphite diester. The key feature of phosphoramidites is their markedly high reactivity towards nucleophiles catalyzed by weak acids e.c., triethylammonium chloride or 1H-tetrazole. In these reactions, the incoming nucleophile replaces the NR₂ moiety.
context_section_description: A phosphoramidite (RO)₂PNR₂ is a monoamide of a phosphite diester. The key feature of phosphoramidites is their markedly high reactivity towards nucleophiles catalyzed by weak acids e.c., triethylammonium chloride or 1H-tetrazole. In these reactions, the incoming nucleophile replaces the NR₂ moiety.
caption: Phosphoramidite: general structure
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