page_title: Adrenocortical adenoma
section_title: Epidemiology
hierarchical_section_title: Adrenocortical adenoma / Epidemiology
caption_attribution_description: English: Incidences and prognoses of adrenal tumors.
context_page_description: Adrenocortical adenoma is commonly described as a benign neoplasm emerging from the cells that comprise the adrenal cortex. Like most adenomas, the adrenocortical adenoma is considered a benign tumor since the majority of them are non-functioning and asymptomatic. Adrenocortical adenomas are classified as ACTH-independent disorders, and are commonly associated with conditions linked to hyperadrenalism such as Cushing's syndrome or Conn's syndrome, which is also known as primary aldosteronism. In addition, recent case reports further support the affiliation of adrenocortical adenomas with hyperandrogenism or florid hyperandrogenism which can cause hyperandrogenic hirsutism in females. "Cushing's syndrome" differs from the "Cushing's disease" even though both conditions are induced by hypercortisolism. The term "Cushing's disease" refers specifically to "secondary hypercortisolism" classified as "ACTH-dependent Cushing's syndrome" caused by pituitary adenomas. In contrast, "Cushing's syndrome" refers specifically to "primary hypercortisolism" classified as "ACTH-independent Cushing's syndrome" caused by adrenal adenomas.
context_section_description: Prevalence: Female > Male
  More common in adults
  Relatively earlier onset in females (ages ≤ 20) than males (ages ≤ 30)
  Most common cause of ACTH-independent Cushing's syndrome
caption: Incidences and prognoses of adrenal tumors,[15] with adrenocortical adenoma at left.
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