page_title: ZCCHC18
section_title: Secondary Structure
hierarchical_section_title: ZCCHC18 / Protein / Secondary Structure
caption_attribution_description: English: ZCCHC18 secondary structure
context_page_description: Zinc finger CCHC-type containing 18 is a protein that in humans is encoded by ZCCHC18 gene. It is also known as Smad-interacting zinc finger protein 2, para-neoplastic Ma antigen family member 7b, and LOC644353. Other names such as zinc finger, CCHC domain containing 12 pseudogene 1, P0CG32, ZCC18_HUMAN had been used to describe this protein.
  ZCCHC18 belongs to the ZCCHC12 family or para-neoplastic Ma. It is a ligand-dependent nuclear receptor transcription coactivator. Its zinc finger domain is CCHC which binds to zinc ion.
  It is worthwhile to mention that in mammals, PNMA is derived from Ty3/Gypsy long terminal repeat retrotransposons and PNMA family encodes the Gag-like protein. Although the full functions remain unknown, most PNMA genes are expressed in brains of macaques and mice. PNMA1, 2 and 3 were found in the serum of patients with paraneoplastic neurological disorders. The family also includes modulator of apoptosis 1, having a role in death receptor-dependent apoptosis.
context_section_description: Secondary structure prediction of a not well-characterized protein can be performed by using PRBI database, Phyre2, and I-TASSER. The secondary structure prediction of ZCCHC18 was analyzed by Phyre2.
caption: ZCCHC18 secondary structure[15]
exif: {}