page_title: Breast cancer classification
section_title: Tubule formation
hierarchical_section_title: Breast cancer classification / Grade / Tubule formation
caption_attribution_description: English: Representative microscopic images of invasive ductal carcinoma with various Nottingham histological grades of Tubule formation. For context, see en:Breast cancer classification.
context_page_description: Breast cancer classification divides breast cancer into categories according to different schemes criteria and serving a different purpose. The major categories are the histopathological type, the grade of the tumor, the stage of the tumor, and the expression of proteins and genes. As knowledge of cancer cell biology develops these classifications are updated.
  The purpose of classification is to select the best treatment. The effectiveness of a specific treatment is demonstrated for a specific breast cancer. That treatment may not be effective in a different breast cancer. Some breast cancers are aggressive and life-threatening, and must be treated with aggressive treatments that have major adverse effects. Other breast cancers are less aggressive and can be treated with less aggressive treatments, such as lumpectomy.
  Treatment algorithms rely on breast cancer classification to define specific subgroups that are each treated according to the best evidence available.
context_section_description: This parameter assesses what percent of the tumor forms normal duct structures. In cancer, there is a breakdown of the mechanisms that cells use to attach to each other and communicate with each other, to form tissues such as ducts, so the tissue structures become less orderly.
  Note: The overall appearance of the tumor has to be considered.
  1 point: tubular formation in more than 75% of the tumor
  2 points: tubular formation in 10 to 75% of the tumor
  3 points: tubular formation in less than 10% of the tumor
caption: Tubule formation score in the Nottingham system
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