page_title: C5orf46
section_title: Expression
hierarchical_section_title: C5orf46 / Expression
caption_attribution_description: English: C5orf46 Expression microarray data comparing psoriasis patients
context_page_description: C5orf46 is a protein coding gene located on chromosome 5 in humans. It is also known as sssp1, or skin and saliva secreted protein 1. There are two known isoforms known in humans, with isoform 2 being the longer of the two. The protein encoded is predicted to have one transmembrane domain, and has a predicted molecular weight of 9,692 Da, and a basal isoelectric point of 4.67.
context_section_description: C5orf46 is largely expressed in salivary glands and skin tissue, though some expression in heart tissue, testis, and placenta is also observed.
  Microarray data measuring c5orf46 expression in psoriasis patients revealed a trend of low expression in patients with lesional psoriasis. Samples from lesional psoriasis patients had significantly lower c5orf46 expression compared to non-lesional psoriasis patients and healthy control samples.
caption: C5orf46 expression microarray data comparisons between healthy and psoriasis patients.[9]
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