page_title: Tenosynovial giant cell tumor
section_title: Localized TGCT
hierarchical_section_title: Tenosynovial giant cell tumor / Localized TGCT
context_page_description: Tenosynovial giant cell tumor is a group of rare, typically non-malignant tumors of the joints. TGCT tumors often develop from the lining of joints.
  Common symptoms of TGCT include swelling, pain, stiffness and reduced mobility in the affected joint or limb. This group of tumors can be divided into different subsets according to their site, growth pattern, and prognosis. Localized TGCT is sometimes referred to as giant cell tumor of the tendon sheath; diffuse TGCT is also called pigmented villonodular synovitis.
context_section_description: Localized TGCT is sometimes referred to as localized pigmented villonodular synovitis (L-PVNS), giant cell tumor of the tendon sheath (GCT-TS), nodular tenosynovitis, localized nodular tenosynovitis, and L-TGCT.
  The localized form of TGCT is more common. Localized TGCT tumors are typically 0.5 cm-4 cm), develop over years, are benign and non-destructive to the surrounding tissue, and may reoccur in the affected area. The most common symptom is painless swelling. Localized TGCT most often occurs in fingers, but can also occur in other joints.
caption: Histopathology of localized TGCT arising in hand finger. H&E stain.
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