page_title: Small nucleolar RNA Z17
hierarchical_section_title: Small nucleolar RNA Z17
caption_attribution_description: English: Image has been uploaded to the Commons as part of the Molecular and Cellular Biology WikiProject in collaboration with the public-domain database Rfam. Here is the link to the discussion.
context_page_description: snoRNA Z17 is a non-coding RNA molecule which functions in the biogenesis of other small nuclear RNAs. This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA and also often referred to as a guide RNA.
  snoRNA Z17 is a member of the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box and the D box. Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. snoRNA Z17B is predicted to guide the 2'-O-ribose methylation of 18S rRNA at position U121. Two forms of this snoRNA are found in the intron of the ribosomal protein L23a gene.
context_section_description: snoRNA Z17 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
  snoRNA Z17 is a member of the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. snoRNA Z17B is predicted to guide the 2'-O-ribose methylation of 18S rRNA at position U121. Two forms of this snoRNA are found in the intron of the ribosomal protein L23a gene.
caption: Predicted secondary structure and sequence conservation of snoZ17
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