page_title: OCC-1
section_title: Homology
hierarchical_section_title: OCC-1 / Homology
caption_attribution_description: English: Phylogenetic Tree for OCC-1
context_page_description: OCC-1 is a protein, which in humans is encoded by the gene C12orf75. The gene is approximately 40,882 bp long and encodes 63 amino acids. OCC-1 is ubiquitously expressed throughout the human body. OCC-1 has shown to be overexpressed in various colon carcinomas.
  Novel splice variant of this gene was also detected in various human cancer types; in addition to encoding a novel smaller protein, OCC-1 gene produces a non-protein coding RNA splice variant lncRNA.
context_section_description: Paralogs:
  OCC-1 has no known paralogs.
  Orthologs:
  OCC-1 has been found in mammalia, reptilia, amphibian, aves, and actinopterygii. The gene is not found in plants, protists, fungi, archaea, or bacteria. The most distant ortholog is the Oryzias latipers or the Japanese rice fish, which diverged from the human gene approximately 436.5 million years ago.
  Phylogeny: 
  The phylogenetic tree to the right shows the evolution of OCC-1 among humans and the orthologs from the various taxa that contain OCC-1. The results of this phylogenetic tree follow in accordance with the predicted evolutionary history of animals on Earth.
caption: OCC-1 Phylogenetic Tree
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