page_title: CCDC180
section_title: Domains
hierarchical_section_title: CCDC180 / Protein / Domains
caption_attribution_description: English: Here are shown the major domains present within the protein CCDC180: Domains of Unknown Function 4455 and 4456, two coiled-coil domains, and a glutamic acid rich domain.
context_page_description: Coiled-coil domain containing protein 180 is a protein that in humans is encoded by the CCDC180 gene. This protein is known to localize to the nucleus and is thought to be involved in regulation of transcription as are many proteins containing coiled-coil domains. As it is expressed most highly in the testes and is regulated by SRY and SOX transcription factors, it could be involved in sex determination.
context_section_description: CCDC180 contains two domains of unknown function (DUFs): DUF4455 and DUF4456.  There are also two coiled-coil regions which overlap with the DUFs.  There is a region of low complexity that is very rich in glutamic acid.
caption: Here are shown the major domains present within the protein CCDC180: Domains of Unknown Function 4455 and 4456, two coiled-coil domains, and a glutamic acid rich domain.
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