page_title: FGFR1OP2
section_title: Expression
hierarchical_section_title: FGFR1OP2 / Expression
caption_attribution_description: English: FGFR1OP2 shows decreased expression in Langerhan cells in Mus musculus.
context_page_description: Fibroblast growth factor receptor oncogene partner 2 was identified in a study on myeloproliferative syndrome. The study aimed to identify the partner genes to the fibroblast growth factor receptor 1 involved in the syndrome. Using the 5'-RACE PCR technique, FGFR1OP2 was identified as a novel gene with no known function.
context_section_description: The expression of FGFR1OP2 was analyzed via the Gene Expression Omnibus at NCBI. The following are findings from the Gene Expression Onmibus database:
  There is a slightly elevated expression level of FGFR1OP2 in pulmonary sarcoidosis, suggesting FGFR1OP2 operates in part of the wound healing pathway.
  FGFR1OP2 is strongly upregulated when compared to the control in an increased immune response triggered by the VAF347 ligand. FGFR1OP2 is upregulated in the monocyte derived dendritic cell response to the VAF347 ligand. VAF347 activates the aryl hydrocarbon receptor and acts on monocytes and naive CD4+ Th cells to promote development of IL-22 secreting Th cells.
  Langerhans cells show decreased expression of FGFR1OP2 with the null aryl hydrocarbon receptor (ligand is VAF347) in Mus musculus.
  The gene is also highly expressed compared to control samples in monocytopenia.
  It is expressed in cases of leukemia; it may have a linkage to the disease.
  FGFR1OP2 shows low expression levels in septic splenocytes in Mus musculus.
  FGFR1OP2 is expressed in fetal reticulocytes but not adult reticulocytes, suggesting it may play a role in the development of red blood cells.
caption: FGFR1OP2 shows decreased expression in Langerhan cells in Mus musculus.
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