page_title: Cysteine-rich secretory protein
hierarchical_section_title: Cysteine-rich secretory protein
caption_attribution_description: English: The two domains of a Cysteine-rich secretory protein (CRISP). Pathogenesis-related protein 1-like omain (PR-1) in white. ShK-like Cysteine-Rich Domain (CRD) in red. Disulphides in yellow. (PDB: 1WVR&#8203;)
context_page_description: Cysteine-rich secretory proteins, often abbreviated as CRISPs, are a group of glycoproteins. They are a subgroup of the CRISP, antigen 5 and Pr-1 protein superfamily and also contain a domain related to the ShK toxins. They are substantially implicated in the functioning of the mammalian reproductive system. CRISPs are also found in a variety of snake venoms where they inhibit both smooth muscle contraction and cyclic nucleotide-gated ion channels.
context_section_description: Cysteine-rich secretory proteins, often abbreviated as CRISPs, are a group of glycoproteins. They are a subgroup of the CRISP, antigen 5 and Pr-1 (CAP) protein superfamily and also contain a domain related to the ShK toxins. They are substantially implicated in the functioning of the mammalian reproductive system. CRISPs are also found in a variety of snake venoms where they inhibit both smooth muscle contraction and cyclic nucleotide-gated ion channels.
caption: The two domains of a Cysteine-rich secretory protein (CRISP).[1] CAP-like PR-1 domain in white. ShK-like CRD in red. Disulphides in yellow. Glycan chains not shown. (PDB: 1WVR​)
exif: {}