page_title: FAM149B1
section_title: Gene
hierarchical_section_title: FAM149B1 / Gene
caption_attribution_description: English: A short segment of Chromosome 10, which shows the location of the FAM149B1 gene and the genes surrounding it.
context_page_description: The Family with sequence similarity 149 member B1 is an uncharacterized protein encoded by the human FAM149B1 gene, with one alias KIAA0974. The protein resides in the nucleus of the cell. The predicted secondary structure of the gene contains multiple alpha-helices, with a few beta-sheet structures. The gene is conserved in mammals, birds, reptiles, fish, and some invertebrates. The protein encoded by this gene contains a DUF3719 protein domain, which is conserved across its orthologues. The protein is expressed at slightly below average levels in most human tissue types, with high expression in brain, kidney, and testes tissues, while showing relatively low expression levels in pancreas tissues.
context_section_description: This gene has a possible 14 exons. It is located on the forward strand of chromosome 10 at 10q22.2 on the positive strand. The total span of the gene, including 5' and 3' UTR, is 3149 base pairs. The gene is flanked on the left by NUDT13 (nudix hydrolase 13) and on the right by DNAJC9-AS1 (DNAJC9 antisense RNA 1).
caption: This figure shows the location of the FAM149B1 gene on Chromosome 10, and also displays the genes in the surrounding location.
exif: {}