page_title: C2orf16
section_title: Structure
hierarchical_section_title: C2orf16 / Protein / Structure
caption_attribution_description: English: C2orf16 Isoform 2 predicted 3D structure showing the three major domains of the protein
context_page_description: C2orf16 is a protein that in humans is encoded by the C2orf16 gene. Isoform 2 of this protein is 1,984 amino acids long. The gene contains 1 exon and is located at 2p23.3. Aliases for C2orf16 include Open Reading Frame 16 on Chromosome 2 and P-S-E-R-S-H-H-S Repeats Containing Sequence.
  68 orthologs are known for this gene, including in mice and sheep, but no paralogs have been found.
context_section_description: The 3D structure of C2orf16 is predicted to have three major domains. Domain 1 is from amino acids 1 to 662, domain 2 is from amino acids 674 to 1,487, and domain 3 is from amino acids 1,488 to 1,984. Domain 1 and 2 are predicted to be connected via a stretch of 12 amino acids not otherwise organized into a secondary structure allowing flexibility between domains 1 and 2. Domain 2 is predicted to have protein interacting domains for transcription factors. Domain 3 is predicted to follow a "balls on a string" structure and has many sites for possible phosphorylation.
caption: C2orf16 Isoform 2 predicted 3D structure showing the three major domains of the protein. Domain 3 contains the P-S-E-R-S-H-H-S repeat sequence.
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