page_title: Cytochrome c oxidase subunit III
hierarchical_section_title: Cytochrome c oxidase subunit III
caption_attribution_description: English: Cartoon representation of the molecular structure of protein registered with 1occ code. Deutsch: Grafik des Molekularstruktur von jenem Protein, das mit 1occ code registriert ist. Plattdüütsch: Grafik, de de Molekularstruktur von dat Protein wiest, dat mit’n Kood 1occ registreert is.
context_page_description: Cytochrome c oxidase subunit III is an enzyme that in humans is encoded by the MT-CO3 gene. It is one of main transmembrane subunits of cytochrome c oxidase. Cytochrome c oxidase subunit III is also one of the three mitochondrial DNA encoded subunits of respiratory complex IV. Variants of MT-CO3 have been associated with isolated myopathy, severe encephalomyopathy, Leber hereditary optic neuropathy, mitochondrial complex IV deficiency, and recurrent myoglobinuria.
context_section_description: Cytochrome c oxidase subunit III (COX3) is an enzyme that in humans is encoded by the MT-CO3 gene. It is one of main transmembrane subunits of cytochrome c oxidase. Cytochrome c oxidase subunit III is also one of the three mitochondrial DNA (mtDNA) encoded subunits (MT-CO1, MT-CO2, MT-CO3) of respiratory complex IV. Variants of MT-CO3 have been associated with isolated myopathy, severe encephalomyopathy, Leber hereditary optic neuropathy, mitochondrial complex IV deficiency, and recurrent myoglobinuria .
caption: Structure of the 13-subunit oxidized cytochrome c oxidase.[4]
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