page_title: POTEB
section_title: Expression
hierarchical_section_title: POTEB / Expression
caption_attribution_description: English: This graph compares POTEB expression in different types of breast cancer cells.
context_page_description: POTE ankyrin domain family, member B is a protein in humans that is encoded by the POTEB gene..It is most likely involved in mediating protein-protein interaction via its 5 ankyrin domains. POTEB is most probably aids in intracellular signaling, but is not likely to be a secreted or nuclear protein. POTEB's function is likely to be regulated via 17 potential phosphorylation sites. There is currently no evidence to suggest that POTEB has nuclear localization signals.
context_section_description: POTEB is expressed at high levels in the human prostate, ovary, and testes. However, there is also evidence to show that it is expressed at low levels in embryonic stem cells, the nasopharyngeal region, and in breast tissue. In embryonic stem cells, differentiation is likely to turn off the expression of POTEB while in breast cancer, triple negative cells are found to have no POTEB expression suggesting a role in cancer-activated pathways. 
  Some studies have used POTEB probes to study the expression of POTEB in the human brain. However, the only region with notable POTEB expression is the cerebellar cortex, responsible for motor function and some cognitive functions.
caption: This graph compares POTEB expression in different types of breast cancer tissue.
exif: {"Image Artist": "Jayanth Jawahar", "Image ExifOffset": "2138", "Image XPAuthor": "Jayanth Jawahar", "Image Padding": "[]", "EXIF DateTimeOriginal": "2017:05:06 15:37:27", "EXIF DateTimeDigitized": "2017:05:06 15:37:27", "EXIF SubSecTimeOriginal": "46", "EXIF SubSecTimeDigitized": "46", "EXIF Padding": "[]"}