page_title: Ganglioneuroma
section_title: Pathology
hierarchical_section_title: Ganglioneuroma / Pathology
caption_attribution_description: English: High magnification micrograph of a ganglioneuroma. Colonic biopsy. H&amp;E stain. Ganglioneuromas may be seen in the context of multiple endocrine neoplasia type 2b, also known as multiple endocrine neoplasia type 3. Related images Low mag. Intermed. mag. Intermed. mag. High mag. High mag. Very high mag.
context_page_description: Ganglioneuroma is a rare and benign tumor of the autonomic nerve fibers arising from neural crest sympathogonia, which are completely undifferentiated cells of the sympathetic nervous system. However, ganglioneuromas themselves are fully differentiated neuronal tumors that do not contain immature elements.
  Ganglioneuromas most frequently occur in the abdomen, however these tumors can grow anywhere sympathetic nervous tissue is found. Other common locations include the adrenal gland, paraspinal retroperitoneum, posterior mediastinum, head, and neck.
context_section_description: Pathologically, ganglioneuromas are composed of ganglion cells, Schwann cells and fibrous tissue. Ganglioneuromas are solid, firm tumours that typically are white when seen with the naked eye.
caption: Micrograph of a ganglioneuroma with the characteristic ganglion cells. H&E stain.
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