page_title: C21orf58
section_title: DNA microarray experimental data
hierarchical_section_title: C21orf58 / Expression / Tissue Expression Pattern / DNA microarray experimental data
caption_attribution_description: English: Sagittal plane view of the mouse brain in situ hybridization of C21orf58 otholog in mouse (2610028H24ik). Expression of C21orf58 color-coated by expression intensity ranging from blue (low intensity) through green to red (high intensity).
context_page_description: Chromosome 21 Open Reading Frame 58 is a protein that in humans is encoded by the C21orf58 gene.
context_section_description: DNA microarray analysis from various experiments showed variable C21orf58 expression in unique physiological conditions.
  An elevated level of C21orf58 expression was observed in astrocytes treated with harmane, a chemical compound associated with essential tremor (ET), compared to control (GDS2919).
  C21orf58 expression up-regulated and then down-regulated in T lymphocytes over time following exposure to Azaspiracid-1 (AZ-10), a marine phycotoxin (GDS3429).
  C21orf58 expression was found to be up-regulated in teratozoopermic individuals compared to expression in normospermic individuals (GDS2697). Teratozoospermia is a condition where sperm have abnormal morphology affecting male fertility.
  
  C21orf58 was found to be expressed through all stages of development at similar levels throughout.
caption: Sagittal plane view of the mouse brain in situ hybridization of C21orf58 otholog in mouse (2610028H24ik). Expression of C21orf58 color-coded by expression intensity ranging from blue (low intensity) through green to red (high intensity).[26] Allen Brain Atlas
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