page_title: Phosphomethylpyrimidine synthase
hierarchical_section_title: Phosphomethylpyrimidine synthase
caption_attribution_description: English: Phosphomethylpyrimidine synthase dimer + 2 AIR (grey-red) + 2 d-adenosine (green-blue-red) + 2 methionine (l.blue-red) + 8 Fe (brown) + 2 Cl (pink), Arabidopsis thaliana (a plant)
context_page_description: Phosphomethylpyrimidine synthase is an enzyme with systematic name 5-amino-1-imidazole formate-lyase. This enzyme catalyses the following chemical reaction
  5-amino-1-imidazole + S-adenosyl-L-methionine 4-amino-2-methyl-5-phosphomethylpyrimidine + 5'-deoxyadenosine + L-methionine + formate + CO
  This enzyme binds a 4Fe-4S cluster.
context_section_description: Phosphomethylpyrimidine synthase (EC 4.1.99.17, thiC (gene)) is an enzyme with systematic name 5-amino-1-(5-phospho-D-ribosyl)imidazole formate-lyase (decarboxylating, 4-amino-2-methyl-5-phosphomethylpyrimidine-forming). This enzyme catalyses the following chemical reaction
  5-amino-1-(5-phospho-D-ribosyl)imidazole + S-adenosyl-L-methionine  4-amino-2-methyl-5-phosphomethylpyrimidine + 5'-deoxyadenosine + L-methionine + formate + CO
  This enzyme binds a 4Fe-4S cluster.
caption: Phosphomethylpyrimidine synthase dimer, Arabidopsis thaliana
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