page_title: 5-Methoxytryptamine
section_title: See also
hierarchical_section_title: 5-Methoxytryptamine / See also
caption_attribution_description: English: Structure of indorenate
context_page_description: 5-Methoxytryptamine, also known as mexamine, is a tryptamine derivative closely related to the neurotransmitters serotonin and melatonin. 5-MT has been shown to occur naturally in the body in low levels. It is biosynthesized via the deacetylation of melatonin in the pineal gland.
  5-MT acts as a full agonist at the 5-HT₁, 5-HT₂, 5-HT₄, 5-HT₆, and 5-HT₇ receptors. It has no affinity for the 5-HT₃ receptor and is affinity for the 5-HT1E receptor is very weak in comparison to the other 5-HT₁ receptors. Its affinity for the 5-HT5A receptor is unknown.
  Measured affinity for some receptors:
  5-HT1B receptors
  5-HT1D receptors
  5-HT1E receptors
  5-HT1F receptors
  5-HT2A receptors
  5-HT2B receptors
  5-HT2C receptors
  5-HT₄ receptors
  5-HT₆ receptors
  5-HT₇ receptors
context_section_description: 2-Methyl-5-hydroxytryptamine
  5-Benzyloxytryptamine
  5-Carboxamidotryptamine
  α-Methyl-5-hydroxytryptamine
  Melatonin
caption: Indorenate
exif: {}