page_title: KI polyomavirus
section_title: Genome
hierarchical_section_title: KI polyomavirus / Genome
caption_attribution_description: English: Schematic diagram of the genome organization of WU virus, a human polyomavirus with genome structure representative of the family. The "early region" is shown at left and encodes two alternatively spliced proteins, the small and large tumor antigens. The "late region" is shown at right and encodes three viral capsid structural proteins. The regulatory region contains the promoters and transcriptional start sites for both regions, and the origin of replication. The whole genome is 5229 base pairs long and consists of circular double-stranded DNA.
context_page_description: KI polyomavirus is a virus of the family Polyomaviridae. It was discovered in 2007 in stored samples of human respiratory secretions collected by the Karolinska Institute, after which the virus is named.
context_section_description: The complete genome of the KI virus has been sequenced and found to be a circular double-stranded DNA genome of 5040 base pairs containing genetic material characteristic of polyomaviruses, encoding five viral proteins: three capsid components, major capsid protein VP1, VP2, and VP3; and two additional proteins involved in replication, the large tumor antigen and small tumor antigen.
caption: Genome structure of the WU virus.[3] KI virus has a near-identical structure with a slightly different length of 5040 base pairs.[1]
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