page_title: Ballooning degeneration
hierarchical_section_title: Ballooning degeneration
caption_attribution_description: English: High magnification micrograph of ballooning degeneration of hepatocytes in steatohepatitis. Liver biopsy. Trichrome stain. In later stages of cell death, cells (undergoing ballooning degeneration) contract/shrink and develop an eosinophilic cytoplasm, at which point they are known as Councilman bodies. See also Image:Non-alcoholic fatty liver disease1.jpg - centrilobular hepatic steatosis. Image:Ballooning degeneration high mag.jpg - an uncropped version of this image. Image:Feathery degeneration high mag cropped.jpg - a histopathologic finding that appears somewhat similar, but is due to other causes.
context_page_description: In histopathology, ballooning degeneration, formally ballooning degeneration of hepatocytes, is a form of liver parenchymal cell death.
  The name is derived from the fact that the cells undergoing this form of cell death increase in size.
  It is generally considered a form of apoptosis, and is a descriptor used in the context of inflamed fatty liver, as well as viral hepatitis.
  The histomorphological appearance of ballooning degeneration is not pathognomonic for steatohepatitis, but usage of the term is generally confined to the condition, i.e. in the context of other histopathological findings the label ballooning degeneration is not used for cell death with cytoplasmic clearing and cell swelling.
context_section_description: In histopathology, ballooning degeneration, formally ballooning degeneration of hepatocytes, is a form of liver parenchymal cell (i.e. hepatocyte) death.  
  The name is derived from the fact that the cells undergoing this form of cell death increase in size (balloon).  
  It is generally considered a form of apoptosis, and is a descriptor used in the context of inflamed fatty liver (steatohepatitis) (which may be due to obesity or alcohol), as well as viral hepatitis.  
  The histomorphological appearance of ballooning degeneration is not pathognomonic for steatohepatitis, but usage of the term is generally confined to the condition, i.e. in the context of other histopathological findings the label ballooning degeneration is not used for cell death with cytoplasmic clearing and cell swelling.
caption: Ballooning degeneration centre-left and centre-right. H&E stain. A Councilman body can also be seen in the upper-right of the section.
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