page_title: Arrow poison
section_title: Plant-based poisons
hierarchical_section_title: Arrow poison / Varieties / Plant-based poisons
caption_attribution_description: Deutsch: Gift-Brechnuss. A Blatt und Blütenzweig, nat. Gr. 1 Blüte, vergrössert; 2 Staubblatt, vergrössert; 3 Narbe, vergrössert. Latina: Strychnos toxifera. Русский: Стрихнос ядоносный. A — лист и цветущая ветвь; 1 — цветок; 2 — тычинка; 3 — рыльце.
context_page_description: Arrow poisons are used to poison arrow heads or darts for the purposes of hunting and warfare. They have been used by indigenous peoples worldwide and are still in use in areas of South America, Africa and Asia. Notable examples are the poisons secreted from the skin of the poison dart frog, and curare, a general term for a range of plant-derived arrow poisons used by the indigenous peoples of South America.
  Poisoned arrows have featured in mythology, notably the Greek story of Heracles slaying the centaur Nessus using arrows poisoned with the blood of the Lernaean Hydra. The Greek hero Odysseus poisons his arrows with hellebore in Homer's Odyssey. Poisoned arrows also figure in Homer's epic about the Trojan War, the Iliad, in which both Achaeans and Trojans used toxic arrows and spears. Poisoned arrows is referred to in the Book of Job in the Bible. The modern terms "toxic" and "toxin" derive from the ancient Greek word for "bow", toxon, from Old Persian *taxa-, "an arrow".
  Poison arrows were used by real people in the ancient world, including the Gauls, ancient Romans, and the nomadic Scythians and Soanes.
context_section_description: Curare is a generic term for arrow poisons that contain tubocurarine, curarine, quinine, protocurarine and related alkaloids.  Most frequently it is derived from the bark of Strychnos toxifera, S. guianensis (family Loganiaceae), Chondrodendron tomentosum or Sciadotenia toxifera (family Menispermaceae). Curare is a competitive antagonist that blocks nicotinic acetylcholine receptors on the post synaptic membrane of the neuromuscular junction. It is a muscle relaxant that causes death by paralyzing the respiratory system, resulting in asphyxiation.
  In Africa, arrow poisons are made from plants that contain cardiac glycosides, such as Acokanthera (possessing ouabain), oleander (Nerium oleander), milkweeds (Asclepias), or Strophanthus, all of which are in the family Apocynaceae.  Inee or onaye is a poison made from Strophanthus hispidus, which contains the cardiac glycoside strophanthin.  It is used in sub-Saharan West Africa, particularly in the areas of Togo and Cameroon.
  Poisoned arrows are used widely in the jungle areas of Assam, Burma and Malaysia. The main plant sources for the poisons are members of the genera Antiaris, Strychnos and Strophanthus. Antiaris toxicaria for example, a tree of the mulberry and breadfruit family, is commonly used on Java and its neighbouring islands. The sap or juice of the seeds is smeared on the arrowhead on its own or mixed with other plant extracts.  The fast-acting active ingredient (either antiarin, strychnine or strophanthin) attacks the central nervous system causing paralysis, convulsions and cardiac arrest.
  Several species of Aconitum or "aconite," belonging to the buttercup family, have been used as arrow poisons. The Minaro in Ladakh use A. napellus on their arrows to hunt Siberian ibex; they were in use recently near lake Issyk Kul in Kyrgyzstan.  The Ainus in Japan used a species of Aconitum to hunt brown bear.  It was also used by the Butias and Lepchas in Sikkim and Assam. The Chinese used Aconitum poisons both for hunting and warfare.
  The Caribs of the Caribbean used poisons made from the sap of the manchineel tree (Hippomane mancinella) or sandbox tree (Hura crepitans), both members of the spurge family, Euphorbiaceae.
caption: Strychnos toxifera, a plant commonly used in the preparation of curare
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