page_title: Thiazole
section_title: Thiazolium salts
hierarchical_section_title: Thiazole / Reactions / Thiazolium salts
context_page_description: Thiazole, or 1,3-thiazole, is a heterocyclic compound that contains both sulfur and nitrogen; the term 'thiazole' also refers to a large family of derivatives. Thiazole itself is a pale yellow liquid with a pyridine-like odor and the molecular formula C₃H₃NS. The thiazole ring is notable as a component of the vitamin thiamine.
context_section_description: Alkylation of thiazoles at nitrogen forms a thiazolium cation.  Thiazolium salts are catalysts in the Stetter reaction and the Benzoin condensation.  Deprotonation of N-alkyl thiazolium salts give the free carbenes and transition metal carbene complexes.
  Alagebrium is a thiazolium-based drug.
caption: Structure of thiazoles (left) and thiazolium salts (right)
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