page_title: Isomaltase
section_title: Mechanism
hierarchical_section_title: Isomaltase / Mechanism
caption_attribution_description: English: Mechanism for how sucrase-isomaltase catalyzes the conversion of isomaltose to two glucose molecules
context_page_description: Isomaltase is an enzyme that breaks the bonds linking saccharides, which cannot be broken by amylase or maltase. It digests polysaccharides at the alpha 1-6 linkages. Its substrate, alpha-limit dextrin, is a product of amylopectin digestion that retains its 1-6 linkage. The product of the enzymatic digestion of alpha-limit dextrin by isomaltase is maltose.
  Isomaltase helps amylase to digest alpha-limit dextrin to produce maltose. The human sucrase-isomaltase is a dual-function enzyme with two GH31 domains, one serving as the isomaltase, the other as a sucrose alpha-glucosidase.
context_section_description: This enzyme catalyses the following chemical reaction
  Hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by enzyme EC 3.2.1.1.
  Hydrolysis uses water to cleave chemical bonds. Sucrase-isomaltase’s mechanism results in a net retention of configuration at the anomeric center.
caption: Mechanism for how sucrase-isomaltase catalyzes the conversion of isomaltose to two glucose molecules
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