page_title: Pyruvate dehydrogenase complex
section_title: Structure
hierarchical_section_title: Pyruvate dehydrogenase complex / Structure
caption_attribution_description: English: Schema of the ox. decarboxylation. For pyruvate (R=H) that is catalyized by the pyruvate dehydrogenase complex Deutsch: Schema der oxidativen Decarboxylierung. Für Pyruvat (R=H) wird dies vom Pyruvat-Dehydrogenase-Komplex katalysiert.
context_page_description: Pyruvate dehydrogenase complex is a complex of three enzymes that converts pyruvate into acetyl-CoA by a process called pyruvate decarboxylation. Acetyl-CoA may then be used in the citric acid cycle to carry out cellular respiration, and this complex links the glycolysis metabolic pathway to the citric acid cycle. Pyruvate decarboxylation is also known as the "pyruvate dehydrogenase reaction" because it also involves the oxidation of pyruvate.
  This multi-enzyme complex is related structurally and functionally to the oxoglutarate dehydrogenase and branched-chain oxo-acid dehydrogenase multi-enzyme complexes.
caption: PDC Mechanism with pyruvate (R=H)
exif: {}