page_title: PYLIS downstream sequence
hierarchical_section_title: PYLIS downstream sequence
caption_attribution_description: Secondary structure of PYLIS-1
context_page_description: In biology, the PYLIS downstream sequence is a stem-loop structure that appears on some mRNA sequences. This structural motif was previously thought to cause the UAG stop codon to be translated to the amino acid pyrrolysine instead of ending the protein translation. However, it has been shown that PYLIS has no effect upon the efficiency of the UAG suppression, hence even its name is, in fact, incorrect.
context_section_description: In biology, the PYLIS downstream sequence (PYLIS: pyrrolysine insertion sequence) is a stem-loop structure that appears on some mRNA sequences. This structural motif was previously thought to cause the UAG (amber) stop codon to be translated to the amino acid pyrrolysine instead of ending the protein translation. However, it has been shown that PYLIS has no effect upon the efficiency of the UAG suppression, hence even its name is, in fact, incorrect.
caption: Predicted secondary structure of PYLIS 1 RNA.
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