page_title: Anatomical pathology
hierarchical_section_title: Anatomical pathology
caption_attribution_description: Another case of villous adenoma of the transverse colon, this one more discrete and polyp-like than the case above. Although it had a semi-decent stalk, it was still far too large for safe removal by endoscopy, so the surgeon was called in to do a segmental resection of the colon. Prior to photographing, the specimen was pinned out in formalin and fixed overnight. The pink color in the center of the mass indicates that the formalin did not penetrate the whole lesion. Shame on me for being chintzy with the formalin! Note how the surface texture of the villous adenoma differs markedly from that of the surrounding colonic mucosa. The photo above was shot with a Nikon D100 digital SLR with Sigma 50mm f/2.8 macro lens. I stopped the diaphragm way down (about f/22) to bring as much of this very three-dimensional lesion as possible into focus. In Photoshop, I resized the image for Web display, sharpened the 'L' channel in Lab mode, and used the Levels command to brighten it a bit. Since many Web users now have flat-panel displays (not as bright as CRTs) and use their monitors in full room lighting, I like to brighten up pictures more than I would for an image that was meant for projection in a properly darkened lecture hall. Photography by Ed Uthman, MD. Public domain. Posted 27 May 01; updated 20 Feb 05
context_page_description: Anatomical pathology or Anatomic pathology is a medical specialty that is concerned with the diagnosis of disease based on the macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues. Over the last century, surgical pathology has evolved tremendously: from historical examination of whole bodies to a more modernized practice, centered on the diagnosis and prognosis of cancer to guide treatment decision-making in oncology. Its modern founder was the Italian scientist Giovan Battista Morgagni from Forlì.
  Anatomical pathology is one of two branches of pathology, the other being clinical pathology, the diagnosis of disease through the laboratory analysis of bodily fluids or tissues. Often, pathologists practice both anatomical and clinical pathology, a combination known as general pathology. Similar specialties exist in veterinary pathology.
context_section_description: Anatomical pathology (Commonwealth) or Anatomic pathology (U.S.) is a medical specialty that is concerned with the diagnosis of disease based on the macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues. Over the last century, surgical pathology has evolved tremendously: from historical examination of whole bodies (autopsy) to a more modernized practice, centered on the diagnosis and prognosis of cancer to guide treatment decision-making in oncology. Its modern founder was the Italian scientist Giovan Battista Morgagni from Forlì.
  Anatomical pathology is one of two branches of pathology, the other being clinical pathology, the diagnosis of disease through the laboratory analysis of bodily fluids or tissues. Often, pathologists practice both anatomical and clinical pathology, a combination known as general pathology.  Similar specialties exist in veterinary pathology.
caption: Gross examination: appearance of a colorectal polyp (the cauliflower-shaped tumor) attached to the colon mucosa (the horizontal line at the bottom).
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