page_title: Negative stain
section_title: Other applications
hierarchical_section_title: Negative stain / Other applications
caption_attribution_description: English: Hexagonal H-II (H), inverterted miceller (M) and lamellar bilayer (le) aqueous lipid phases by negative staining transmission electron microscopy.
context_page_description: In microscopy, negative staining is an established method, often used in diagnostic microscopy, for contrasting a thin specimen with an optically opaque fluid. In this technique, the background is stained, leaving the actual specimen untouched, and thus visible. This contrasts with positive staining, in which the actual specimen is stained.
context_section_description: Negative staining transmission electron microscopy has also been successfully employed for study and identification of aqueous lipid aggregates like lamellar liposomes (le), inverted spherical micelles (M) and inverted hexagonal HII cylindrical (H) phases (see figure).
caption: Identification of lamellar(le), reverse-miceller(M) and reverse-hexagonal H-II cylinders(H) lipid phases by negative staining.
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