page_title: Azoxystrobin
section_title: Mechanism of action
hierarchical_section_title: Azoxystrobin / Mechanism of action
caption_attribution_description: English: PDB 1NTZ, created using Pymol
context_page_description: Azoxystrobin is the ISO common name for an organic compound that is used as a pesticide. It is a broad spectrum systemic fungicide widely used in agriculture to protect crops from fungal diseases. It was first marketed in 1996 using the brand name Amistar and by 1999 it had been registered in 48 countries on more than 50 crops. In the year 2000 it was announced that it had been granted UK Millennium product status.
context_section_description: Azoxystrobin and other strobilurins inhibit mitochondrial respiration by blocking electron transport. They bind at the quinol outer binding site of the cytochrome b-c1 complex, where ubiquinone (coenzyme Q10) would normally bind when carrying electrons to that protein. Thus production of ATP is prevented. The generic name for this mode of action is "Quinone Outside Inhibitors" QoI.
caption: Cytochrome bc1 with bound ubiquinone
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