page_title: Bio Base Europe
section_title: Bio Base Europe Pilot Plant
hierarchical_section_title: Bio Base Europe / Bio Base Europe Pilot Plant
caption_attribution_description: English: Pilot scale fermenters with volumes of 100 L, 4500L and 15000L
context_page_description: Bio Base Europe is an innovation and training center for the biobased economy. It is a platform that supports the development of sustainable, biobased products such as bio-chemicals, bio-plastics, bio-materials, bio-detergents, bio-energy, etc. from renewable biomass resources. Its mission is to stimulate sustainable development and economic growth by facilitating R&D and training for biobased process development. It consists of a Pilot Plant for the biobased economy located in the port of Ghent, and a Training Center for the biobased economy in Terneuzen.
context_section_description: Bio Base Europe Pilot Plant is a pilot test facility for the biobased economy, built with the aim to close the gap between scientific feasibility and industrial application.  It operates from kg to ton scale. The pilot plant hosts a range of process equipment to scale up biobased processes to industrial scale. Tests done in the pilot plant enable to assess operating costs, specific strengths and weaknesses of new biobased processes before costly, large-scale investments in production plant facilities are made. Bio Base Europe Pilot Plant has no industrial shareholders, and operates according to the open innovation service model. Companies and research centres throughout the world that are active in the biobased economy can access these facilities for their technological developments.
  The processes done in the pilot plant can be divided into the following categories
  1.	Biorefining: Biomass fractionation and pretreatment
  2.	Industrial biotechnology
  3.	Green chemistry
  4.	Downstream processing
  In the biorefining operations, biomass can be fractionated in its various parts. These operations involve a.o. milling and pulping, dispersion, homogenizing, physical separation such as centrifugation and decantation, filtration including dead end particulate filtration and cross flow membrane filtration,… Biomass can also be pretreated prior to enzymatic hydrolysis, involving pulping and homogenisation reactions, jet cooking, acid or alcaline treatment, steam explosion, etc. 
  White or industrial biotechnology processes involves the use of microorganisms and their enzymes in so-called fermentation processes or biocatalytic reactions. Fermentations can be performed from 1 to 15.000 litre scale and involve both batch, fed batch or continuous operations. Reactors for enzymatic reactions are present that can be used with either water of organic solvents.
  Green chemistry is performed in explosion proof installations such as glass-lined chemical reactors (1 - 6.000 l scale) that are suited to perform under vacuum or under pressure. The Bio Base Europe Pilot Plant is also equipped with filter dryers for solvent extraction of liquids and solids.
  Downstream processing for the recovery of pure products after biochemical or chemical conversion involves various equipment for extraction, evaporation, demineralization, ion exchange, carbon treatment, crystallization, spray drying, lyophilisation, etc.
  Continuous process lines can be built up by connecting unit operations with mobile positive and centrifugal pumps, heat exchangers, dosing pumps, flexible and fixed piping and instrumentation.
caption: Fermenters at Bio Base Europe with volumes of 100L, 4500L and 15000L.
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