page_title: MRC-5
hierarchical_section_title: MRC-5
caption_attribution_description: Transmission electron micrograph of Middle Eastern Respiratory Syndrome virusCoV particles found in the lumen of the endoplasmic reticulum in an infected MRC-5 cell. Credit: NIAID
context_page_description: MRC-5 is a diploid human cell culture line composed of fibroblasts, originally developed from research deriving lung tissue of a 14-week-old aborted Caucasian male fetus. The cell line was isolated by J.P. Jacobs and colleagues in September 1966 from the seventh population doubling of the original strain, and MRC-5 cells themselves are known to reach senescence in around 45 population doublings.
context_section_description: MRC-5 (Medical Research Council cell strain 5) is a diploid human cell culture line composed of fibroblasts, originally developed from research deriving lung tissue of a 14-week-old aborted Caucasian male fetus. The cell line was isolated by J.P. Jacobs and colleagues in September 1966 from the seventh population doubling of the original strain, and MRC-5 cells themselves are known to reach senescence in around 45 population doublings.
caption: MERS coronavirus particles found in the lumen of the endoplasmic reticulum in an infected MRC-5 cell
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