page_title: Amide
hierarchical_section_title: Amide
caption_attribution_description: Description: Structural formula of a general amide group (RCONR'R''). Author, date of creation: self made by Ben Mills at 17:12, 8 March 2006 (UTC). Source: user-created image Comments: high-resolution black and white PNG; ChemDraw / Photoshop.
context_page_description: In organic chemistry, an amide, also known as an organic amide or a carboxamide, is a compound with the general formula RCNR′R″, where R, R', and R″ represent organic groups or hydrogen atoms. The amide group is called a peptide bond when it is part of the main chain of a protein, and isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. It can be viewed as a derivative of a carboxylic acid RCOH with the hydroxyl group –OH replaced by an amine group –NR′R″; or, equivalently, an acyl group RC– joined to an amine group.
  Common examples of amides are acetamide H₃C–CONH2, benzamide C₆H₅–CONH2, and dimethylformamide HCON(–CH₃)₂.
  Amides are qualified as primary, secondary, and tertiary according to whether the amine subgroup has the form –NH₂, –NHR, or –NRR', where R and R' are groups other than hydrogen.
  The core –CN= of amides is called the amide group.
  Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups; these linkages are easily formed, confer structural rigidity, and resist hydrolysis.
context_section_description: In organic chemistry, an amide, also known as an organic amide or a carboxamide, is a compound with the general formula RC(=O)NR′R″, where R, R', and R″ represent organic groups or hydrogen atoms. The amide group is called a peptide bond when it is part of the main chain of a protein, and isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. It can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group –NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)– joined to an amine group.
  Common examples of amides are acetamide H₃C–CONH2, benzamide C₆H₅–CONH2, and dimethylformamide HCON(–CH₃)₂.
  Amides are qualified as primary, secondary, and tertiary according to whether the amine subgroup has the form –NH₂, –NHR, or –NRR', where R and R' are groups other than hydrogen.
  The core –C(=O)N= of amides is called the amide group (specifically, carboxamide group).
  Amides are pervasive in nature and technology.  Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis.  Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low molecular weight amides, such as dimethylformamide, are common solvents.
caption: General structure of an amide (specifically, a carboxamide).
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