page_title: Precorrin-8X methylmutase
hierarchical_section_title: Precorrin-8X methylmutase
caption_attribution_description: English: Crystal structure of precorrin-8x methyl mutase.
context_page_description: In enzymology, a precorrin-8X methylmutase is an enzyme that catalyzes the chemical reaction
  precorrin-8X hydrogenobyrinate
  Hence, this enzyme has one substrate, precorrin 8X, and one product, hydrogenobyrinate.
  This enzyme belongs to the family of isomerases, specifically those intramolecular transferases transferring other groups. The systematic name of this enzyme class is precorrin-8X 11,12-methylmutase. Other names in common use include precorrin isomerase, hydrogenobyrinic acid-binding protein and CobH. This enzyme is part of the biosynthetic pathway to cobalamin in aerobic bacteria.
context_section_description: In enzymology, a precorrin-8X methylmutase (EC 5.4.99.61) is an enzyme that catalyzes the chemical reaction
  precorrin-8X  hydrogenobyrinate
  Hence, this enzyme has one substrate, precorrin 8X, and one product, hydrogenobyrinate.
  This enzyme belongs to the family of isomerases, specifically those intramolecular transferases transferring other groups.  The systematic name of this enzyme class is precorrin-8X 11,12-methylmutase. Other names in common use include precorrin isomerase, hydrogenobyrinic acid-binding protein and CobH. This enzyme is part of the biosynthetic pathway to cobalamin (vitamin B₁₂) in aerobic bacteria.
caption: Crystal structure of precorrin-8x methyl mutase with bound hydrogenobyrinate. PDB 1i1h[1]
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