page_title: TAR syndrome
section_title: Genetics
hierarchical_section_title: TAR syndrome / Genetics
caption_attribution_description: English: Relation between chromosome 1 and 1q21.1, the TAR syndrome and 1q21.1 deletion / duplication syndrome
context_page_description: TAR syndrome is a rare genetic disorder that is characterized by the absence of the radius bone in the forearm and a dramatically reduced platelet count.
context_section_description: This condition requires mutations in both chromosomes. The first mutation is  inheritance of a 1q21.1 deletion and the second is in the remaining in the RBM8A gene.  Approximately 95% of TAR patients have one non-functional copy of the RBM8A gene.
caption: The cytogenetic location (pink box) of the RBM8A gene 0lon 1q21.1
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