page_title: Acetyl-CoA synthetase
section_title: Intracellular
hierarchical_section_title: Acetyl-CoA synthetase / Industrial application / Intracellular
caption_attribution_description: English: metabolic pathway for synthesis of faee from acetate
context_page_description: Acetyl-CoA synthetase or Acetate-CoA ligase is an enzyme involved in metabolism of acetate. It is in the ligase class of enzymes, meaning that it catalyzes the formation of a new chemical bond between two large molecules.
context_section_description: Acetyl-CoA from the breakdown of sugars in glycolysis have been used to build fatty acids. However the difference comes in the fact that the Keasling strain is able to synthesize its own ethanol, and process (by transesterification) the fatty acid further to create stable fatty acid ethyl esters (FAEEs). Removing the need for further processing prior to obtaining a usable fuel product in Diesel engines.
  Acetyl CoA used in the production of both ethanol and fatty acids
caption: Regulation changes to E. coli for production of FAEE from acetate.
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