page_title: Glyceraldehyde 3-phosphate dehydrogenase
hierarchical_section_title: Glyceraldehyde 3-phosphate dehydrogenase
caption_attribution_description: English: Cartoon representation of the molecular structure of protein registered with 2czc code. Deutsch: Grafik des Molekularstruktur von jenem Protein, das mit 2czc code registriert ist. Plattdüütsch: Grafik, de de Molekularstruktur von dat Protein wiest, dat mit’n Kood 2czc registreert is.
context_page_description: Glyceraldehyde 3-phosphate dehydrogenase is an enzyme of ~37kDa that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules. In addition to this long established metabolic function, GAPDH has recently been implicated in several non-metabolic processes, including transcription activation, initiation of apoptosis, ER to Golgi vesicle shuttling, and fast axonal, or axoplasmic transport. In sperm, a testis-specific isoenzyme GAPDHS is expressed.
context_section_description: Glyceraldehyde 3-phosphate dehydrogenase (abbreviated as GAPDH or less commonly as G3PDH) (EC 1.2.1.12) is an enzyme of ~37kDa that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules. In addition to this long established metabolic function, GAPDH has recently been implicated in several non-metabolic processes, including transcription activation, initiation of apoptosis, ER to Golgi vesicle shuttling, and fast axonal, or axoplasmic transport. In sperm, a testis-specific isoenzyme GAPDHS is expressed.
caption: crystal structure of glyceraldehyde-3-phosphate dehydrogenase from pyrococcus horikoshii ot3
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