page_title: Aequorin
hierarchical_section_title: Aequorin
caption_attribution_description: English: Aequorin ribbon diagram PDB 1eJ3. Presented is chain A. Hereby the substrate analoge is in blue, the tyrosine 184 in pink.Deutsch: Schematische Darstellung von Aequorin, Kette A der Kristallstruktur. In blau ist das Substratanalog, in pink Tyrosin 184 abgebildet.
context_page_description: Aequorin is a calcium-activated photoprotein isolated from the hydrozoan Aequorea victoria. Though the bioluminescence was studied decades before, the protein was isolated in 1962 from the animal by Osamu Shimomura. In the animals, the protein occurs together with the green fluorescent protein to produce green light by resonant energy transfer, while aequorin by itself generates blue light.
  Discussions of "jellyfish DNA" to make "glowing" animals often refer to transgenic animals that express the green fluorescent protein, not aequorin, although both originally derived from the same animal.
  Apoaequorin, the protein portion of aequorin, is an ingredient in the dietary supplement Prevagen. The US Federal Trade Commission has charged the maker with false advertising for its memory improvement claims.
context_section_description: Aequorin is a calcium-activated photoprotein isolated from the hydrozoan Aequorea victoria. Though the bioluminescence was studied decades before, the protein was isolated in 1962 from the animal by Osamu Shimomura. In the animals, the protein occurs together with the green fluorescent protein to produce green light by resonant energy transfer, while aequorin by itself generates blue light.
  Discussions of "jellyfish DNA" to make "glowing" animals often refer to transgenic animals that express the green fluorescent protein, not aequorin, although both originally derived from the same animal.
  Apoaequorin, the protein portion of aequorin, is an ingredient in the dietary supplement Prevagen. The US Federal Trade Commission (FTC) has charged the maker with false advertising for its memory improvement claims.
caption: Aequorin ribbon diagram from PDB 1ej3 with prosthetic group coelenterazine in blue
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