page_title: Leukocyte extravasation
section_title: Introduction
hierarchical_section_title: Leukocyte extravasation / Molecular biology / Introduction
caption_attribution_description: Deutsch: Schematische Darstellung der Leukozytenmigration durch das Endothel. Nach einer Grafik von U. H. von Andrian und C. R. Mackay: T-Cell Function and Migration. In: NEJM. October 5th, 2000, S.&#160;1025. Und K. Ley et al.: Getting to the site of inflammation: the leukocyte adhesion cascade updated. In: Nature Reviews Immunology 7, 2007, S.&#160;679 Français&#160;: Schéma de la migration des leucocytes à travers l'endothélium. D'après un dessin de U. H. von Andrian et C. R. Mackay&#160;: T-Cell Function and Migration. dans&#160;: NEJM. 5 octobre 2000, p. 1025&#160;; et K. Ley et al.&#160;: Getting to the site of inflammation&#160;: the leukocyte adhesion cascade updated. dans&#160;: Nature Reviews Immunology 7, 2007, p. 679
context_page_description: Leukocyte extravasation is the movement of leukocytes out of the circulatory system and towards the site of tissue damage or infection. This process forms part of the innate immune response, involving the recruitment of non-specific leukocytes. Monocytes also use this process in the absence of infection or tissue damage during their development into macrophages.
context_section_description: The phases of the leukocyte extravasation depicted in the schema are: approach, capture, rolling, activation, binding, strengthening of the binding and spreading, intravascular creeping, paracellular migration or transcellular migration.
caption: Leukocyte extravasation
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