page_title: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
hierarchical_section_title: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
caption_attribution_description: English: Cartoon representation of the molecular structure of protein registered with 1w77 code. Deutsch: Grafik des Molekularstruktur von jenem Protein, das mit 1w77 code registriert ist. Plattdüütsch: Grafik, de de Molekularstruktur von dat Protein wiest, dat mit’n Kood 1w77 registreert is.
context_page_description: In enzymology, a 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase is an enzyme that catalyzes the chemical reaction:
  2-C-methyl-D-erythritol 4-phosphate + CTP diphosphate + 4--2-C-methyl-D-erythritol
  Thus, the two substrates of this enzyme are CTP and 2-C-methyl-D-erythritol 4-phosphate, whereas its two products are diphosphate and 4-diphosphocytidyl-2-C-methylerythritol.
  This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups.
  This enzyme participates in isoprenoid biosynthesis and stenvenosim. It catalyzes the third step of the MEP pathway; the formation of CDP-ME from CTP and MEP. The isoprenoid pathway is a well known target for anti-infective drug development.
context_section_description: In enzymology, a 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (EC 2.7.7.60) is an enzyme that catalyzes the chemical reaction:
  2-C-methyl-D-erythritol 4-phosphate + CTP  diphosphate + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol
  Thus, the two substrates of this enzyme are CTP and 2-C-methyl-D-erythritol 4-phosphate, whereas its two products are diphosphate and 4-diphosphocytidyl-2-C-methylerythritol.
  This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases).
  This enzyme participates in isoprenoid biosynthesis and stenvenosim. It catalyzes the third step of the MEP pathway; the formation of CDP-ME (4-diphosphocytidyl-2C-methyl-D-erythritol) from CTP and MEP (2C-methyl-D-erythritol 4-phosphate). The isoprenoid pathway is a well known target for anti-infective drug development.
caption: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (IspD) from Arabidopsis thaliana
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