page_title: TMEM8B
section_title: Secondary Structure
hierarchical_section_title: TMEM8B / Protein / Secondary Structure
caption_attribution_description: secondary structure predicted to come from tMEM8B
context_page_description: Transmembrane protein 8B is a protein that in humans is encoded by the TMEM8B gene. It encodes for a transmembrane protein that is 338 amino acids long, and is located on human chromosome 9. Aliases associated with this gene include C9orf127, NAG-5, and NGX61.
context_section_description: Identifying the secondary structure is helpful in further analyzing the function of this protein. Alpha helices are the strongest indicators of transmembrane regions, as the helical structure can satisfy all backbone hydrogen-bonds internally. This is why the secondary structure of this protein is practical, as many of the alpha helices lie in the predicted transmembrane regions. Other key structures identified in this protein include extended strands, which are hypothesized to be important folding regions, and random coils, a class of conformations in the absence of a regular secondary structure.
caption: Figure 2: Predicted secondary structure of TMEM8B, Isoform A. Predicted transmembrane domains are highlighted in green
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