page_title: Immunostaining
hierarchical_section_title: Immunostaining
caption_attribution_description: English: Very high magnification micrograph of an anaplastic astrocytoma. GFAP immunostain. The typical features are present: Marked nuclear atypia. Elongated nuclei (consistent with derivation from an astrocyte ). Mitoses. Fine fibrillary processes (consistent with a glial cell population). Cytoplasmic staining of atypical cells with GFAP. p53 immunohistochemical stain positivity. High proliferative rate based on Ki-67 staining. Related images Low mag. Intermed. mag. High mag. Very high mag. Ki-67. High mag. p53. Very high mag.
context_page_description: In biochemistry, immunostaining is any use of an antibody-based method to detect a specific protein in a sample. The term "immunostaining" was originally used to refer to the immunohistochemical staining of tissue sections, as first described by Albert Coons in 1941. However, immunostaining now encompasses a broad range of techniques used in histology, cell biology, and molecular biology that use antibody-based staining methods.
context_section_description: In biochemistry, immunostaining is any use of an antibody-based method to detect a specific protein in a sample. The term "immunostaining" was originally used to refer to the immunohistochemical staining of tissue sections, as first described by Albert Coons in 1941. However, immunostaining now encompasses a broad range of techniques used in histology, cell biology, and molecular biology that use antibody-based staining methods.
caption: Micrograph of a GFAP immunostained section of a brain tumour.
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