page_title: Cyclophosphamide
section_title: Cancer
hierarchical_section_title: Cyclophosphamide / Medical uses / Cancer
caption_attribution_description: English: Title: Treatment: IV Bottle Description: Shown is a close-up of an intravenous (IV) bottle. The photograph is taken looking up at the bottle. Subjects (names): Topics/Categories: Treatment -- Drugs/Chemotherapy Type: Color Slide Source: National Cancer Institute Author: Linda Bartlett (photographer) AV Number: AV-8000-0596 Date Created: 1980 Date Added: 1/1/2001 Reuse Restrictions: None - This image is in the public domain and can be freely reused. Please credit the source and/or author listed above.
context_page_description: Cyclophosphamide, also known as cytophosphane among other names, is a medication used as chemotherapy and to suppress the immune system. As chemotherapy it is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and sarcoma. As an immune suppressor it is used in nephrotic syndrome, granulomatosis with polyangiitis, and following organ transplant, among other conditions. It is taken by mouth or injection into a vein.
  Most people develop side effects. Common side effects include low white blood cell counts, loss of appetite, vomiting, hair loss, and bleeding from the bladder. Other severe side effects include an increased future risk of cancer, infertility, allergic reactions, and pulmonary fibrosis. Cyclophosphamide is in the alkylating agent and nitrogen mustard family of medications. It is believed to work by interfering with the duplication of DNA and the creation of RNA.
  Cyclophosphamide was approved for medical use in the United States in 1959. It is on the World Health Organization's List of Essential Medicines.
context_section_description: The main use of cyclophosphamide is with other chemotherapy agents in the treatment of lymphomas, some forms of brain cancer, neuroblastoma, leukemia and some solid tumors.
caption: Cyclophosphamide IV drip
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