page_title: Protein FAM46B
section_title: Expression
hierarchical_section_title: Protein FAM46B / Expression
caption_attribution_description: English: Expression of FAM46B, broken down by tissue type and health state. Data obtained from the NCBI UniGene page
context_page_description: Protein FAM46B also known as family with sequence similarity 46 member B is a protein that in humans is encoded by the FAM46B gene. FAM46B contains one protein domain of unknown function, DUF1693. Yeast two-hybrid screening has identified three proteins that physically interact with FAM46B. These are ATX1, PEPP2 and DAZAP2.
context_section_description: Expression can be assessed in a variety of ways. Both expressed sequence tags and GEO profiles show the number of transcripts of a gene present in a certain tissue type and relative to the total gene transcripts. Microarrays are also useful in quantifying gene expression. Protein in-situ hybridization is a more accurate measure of expression than mRNA or cDNA based methods, as probes can be fused directly to the protein.
  According to some available microarray data, FAM46B is highly expressed in the tongue (levels 10x above mean gene expression for the tissue). Outside of the tongue, FAM46B seems to be uniformly expressed across most tissues. In addition to gene expression in healthy tissues, EST data also highlights gene expression by health state. It appears FAM46B expression is elevated in cases of skin cancer and gliomas.
caption: Expression of FAM46B, broken down by tissue type and health state. Data obtained from the NCBI UniGene page
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