page_title: TM6SF2
section_title: Domains and motifs
hierarchical_section_title: TM6SF2 / Protein / Domains and motifs
caption_attribution_description: English: This image shows the topology of TM6SF2 protein as predicted by SOSUI &#91;1&#93; The red stars indicate probable phosphorylation sites.
context_page_description: TM6SF2 is the Transmembrane 6 superfamily 2 human gene which codes for a protein by the same name. This gene is otherwise called KIAA1926. Its exact function is currently unknown.
context_section_description: There is a domain of unknown function, DUF2781 ( pfam10914 family) spanning amino acids 218 to 359 in the C-terminus of the protein.
  There are nine transmembrane regions in this protein. The first one contains the signal peptide which is eventually cleaved following protein localization to the ER. A terminal KHHQ sequence is an endoplasmic reticulum retention signal.
caption: Conceptual TM6SF2 protein with phosphorylation sites
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