page_title: Ehlers–Danlos syndromes
section_title: Notable cases
hierarchical_section_title: Ehlers–Danlos syndromes / Society and culture / Notable cases
caption_attribution_description: English: Miss Allegany County Victoria Graham is standing in front of the Ehlers-Danlos Syndrome exhibit at Rare Disease Day at the National Institutes of Health (NIH) in 2018.
context_page_description: Ehlers–Danlos syndromes are a group of rare genetic connective tissue disorders. Symptoms may include loose joints, joint pain, stretchy velvety skin, and abnormal scar formation. These can be noticed at birth or in early childhood. Complications may include aortic dissection, joint dislocations, scoliosis, chronic pain, or early osteoarthritis.
  EDS occurs due to variations of more than 19 different genes which are present at birth. The specific gene affected determines the type of EDS. Some cases result from a new variation occurring during early development, while others are inherited in an autosomal dominant or recessive manner. Typically, these variations result in defects in the structure or processing of the protein collagen. Diagnosis is often based on symptoms and confirmed with genetic testing or skin biopsy. However, people may initially be misdiagnosed with hypochondriasis, depression, or chronic fatigue syndrome.
  There is no known cure. Treatment is supportive in nature. Physical therapy and bracing may help strengthen muscles and support joints.
context_section_description: Youtuber Stevie Boebi.
  Actress Cherylee Houston, hypermobile EDS. She uses a wheelchair and was the first full-time disabled actress on Coronation Street.
  Drag queen and winner of the eleventh season of RuPaul's Drag Race Yvie Oddly
  Eric the Actor, a regular caller to The Howard Stern Show
  Actress and activist Jameela Jamil, hypermobile EDS. EDS is now part of her body positivity movements.
  Writer and actress Lena Dunham
  Australian singer Sia
  YouTuber and disability rights activist Annie Elainey
  Miss America 2020 Camille Schrier
  Miss America pageant contestant (and Miss Allegany County) Victoria Graham
caption: Pageant contestant Victoria Graham has EDS
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