page_title: Febuxostat
section_title: Medical uses
hierarchical_section_title: Febuxostat / Medical uses
caption_attribution_description: English: Uloric 40 mg tablet
context_page_description: Febuxostat, sold under the brand names Uloric and Adenuric among others, is a medication used long-term to treat gout due to high uric acid levels. It is generally recommended only for people who cannot take allopurinol. When initially started, medications such as NSAIDs are often recommended to prevent gout flares. It is taken by mouth.
  Common side effects include liver problems, nausea, joint pain, and a rash. Serious side effects include an increased risk of death as compared with allopurinol, Stevens–Johnson syndrome, and anaphylaxis. Use is not recommended during pregnancy or breastfeeding. It inhibits xanthine oxidase, thus reducing production of uric acid in the body.
  Febuxostat was approved for medical use in the European Union in 2008 and in the United States in 2009. A generic version was approved in 2019 and is available as of 2020.
context_section_description: Febuxostat is used to treat chronic gout and hyperuricemia.  Febuxostat is typically recommended only for people who cannot tolerate allopurinol. National Institute for Health and Clinical Excellence concluded that febuxostat is more effective than standard doses of allopurinol, but not more effective than higher doses of allopurinol.
  Febuxostat is in the US pregnancy category C; there are no adequate and well-controlled studies in pregnant women.
caption: Uloric 40 mg tablet
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