page_title: Emery–Dreifuss muscular dystrophy
section_title: Genetics
hierarchical_section_title: Emery–Dreifuss muscular dystrophy / Genetics
caption_attribution_description: English: Structure of the LMNA protein. Based on PyMOL rendering of PDB 1ifr.
context_page_description: Emery–Dreifuss muscular dystrophy is a condition that mainly affects muscles used for movement, such as skeletal muscles and also affects the cardiac muscle, it is named after Alan Eglin H. Emery and Fritz E. Dreifuss.
context_section_description: Mutations in the EMD, LMNA, and several other genes cause the various types of Emery–Dreifuss muscular dystrophy. The EMD and LMNA genes provide instructions for making proteins that are components of the nuclear envelope, which surrounds the nucleus in cells. The nuclear envelope regulates the movement of molecules into and out of the nucleus, and researchers believe it may play a role in regulating the activity of certain genes.
caption: Protein LMNA
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