page_title: John Hibbs (academic)
hierarchical_section_title: John Hibbs (academic)
caption_attribution_description: English: John Hibbs
context_page_description: John B. Hibbs Jr. is an American physician-scientist and educator. He is Distinguished Professor Emeritus in the Department of Medicine at the University of Utah.
  He is known for the discovery of the direct synthesis of L-citrulline and nitrogen oxides from L-arginine by murine activated macrophages, published in January 1987. This reaction was inhibited strongly by the non-toxic NG-monomethyl-L-arginine molecule. These observations provided the biochemical tools needed to establish the new and unexpected ﬁeld of nitric oxide biochemistry and made possible its rapid initial progress in cardiovascular and neural physiology. In 1988, he directly measured the gas nitric oxide, simultaneously with Michael Marletta, showing that it is the proximal nitrogen oxide produced during the biological oxidation of a terminal guanidino nitrogen atom of L-arginine.
context_section_description: John B. Hibbs Jr. is an American physician-scientist and educator. He is Distinguished Professor Emeritus in the Department of Medicine at the University of Utah.
  He is known for the discovery of the direct synthesis of L-citrulline and nitrogen oxides from L-arginine by murine activated macrophages, published in January 1987. This reaction was inhibited strongly by the non-toxic NG-monomethyl-L-arginine molecule. These observations provided the biochemical tools needed to establish the new and unexpected ﬁeld of nitric oxide biochemistry and made possible its rapid initial progress in cardiovascular and neural physiology. In 1988, he directly measured the gas nitric oxide, simultaneously with Michael Marletta, showing that it is the proximal nitrogen oxide produced during the biological oxidation of a terminal guanidino nitrogen atom of L-arginine.
caption: Hibbs in 2020
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