page_title: Epimorphosis
section_title: In vertebrates
hierarchical_section_title: Epimorphosis / In vertebrates
caption_attribution_description: English: Title: The elements of experimental embryology Identifier: elementsofexperi00huxl (find matches) Year: 1963 (1960s) Authors: Huxley, Julian, 1887-1975; De Beer, Gavin, Sir, 1899-1972 Subjects: Embryology, Experimental; Embryology Publisher: New York (Hafner Pub. Co. ) Contributing Library: MBLWHOI Library Digitizing Sponsor: MBLWHOI Library View Book Page: Book Viewer About This Book: Catalog Entry View All Images: All Images From Book Click here to view book online to see this illustration in context in a browseable online version of this book. Text Appearing Before Image: ' Text Appearing After Image: c Fig. 145 Regeneration is determined by the level of amputation within the limb-field, and not with reference to the organism as a whole. A, Dorsal, and B, Ventral, views of a newt (Triton) in which the legs were amputated above the thigh, and shanks were grafted in their place and subsequently amputated. C, Radiogram, showing that only the tarsus and foot have been regenerated: i.e. structures distal to the graft. (From Guyenot, Rev. Suisse de Zool. xxxiv, 1927.) Note About Images Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original work.
context_page_description: Epimorphosis is defined as the regeneration of a specific part of an organism in a way that involves extensive cell proliferation of somatic stem cells, dedifferentiation, and reformation, as well as blastema formation.Epimorphosis can be considered a simple model for development, though it only occurs in tissues surrounding the site of injury rather than occurring system-wide.Epimorphosis restores the anatomy of the organism and the original polarity that existed before the destruction of the tissue and/or a structure of the organism. Epimorphosis regeneration can be observed in both vertebrates and invertebrates such as the common examples: salamanders, annelidas, and planarians.
context_section_description: In vertebrates, epimorphosis relies on blastema formation to proliferate cells into the new tissue. Through studies involving zebrafish fins, the toetips of mice, and limb regeneration in axolotls, researchers at the Polish Academy of Sciences found evidence for epimorphosis occurring in a variety of vertebrates, including instances of mammal epimorphosis.
caption: Dorsal and ventral views of a newt that has had a limb amputated and regrown, from "The elements of experimental embryology"[9] by Julian Huxley and Gavin de Beer.
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