page_title: Heme oxygenase
hierarchical_section_title: Heme oxygenase
caption_attribution_description: English: Cartoon representation of the molecular structure of protein registered with 1twr code. Deutsch: Grafik des Molekularstruktur von jenem Protein, das mit 1twr code registriert ist. Plattdüütsch: Grafik, de de Molekularstruktur von dat Protein wiest, dat mit’n Kood 1twr registreert is.
context_page_description: Heme oxygenase or haem oxygenase is an enzyme that catalyzes the degradation of heme. This produces biliverdin, ferrous iron, and carbon monoxide. HO was first described in the late 1960s when Raimo Tenhunen demonstrated an enzymatic reaction for heme catabolism. HO is the premier source for endogenous carbon monoxide production. Indeed, monitored small doses of CO are being studied for therapeutic benefits.
context_section_description: Heme oxygenase or haem oxygenase (HO) is an enzyme that catalyzes the degradation of heme. This produces biliverdin, ferrous iron, and carbon monoxide.  HO was first described in the late 1960s when Raimo Tenhunen demonstrated an enzymatic reaction for heme catabolism. HO is the premier source for endogenous carbon monoxide (CO) production. Indeed, monitored small doses of CO are being studied for therapeutic benefits.
caption: Crystal structures of ferrous and ferrous-no forms of verdoheme in a complex with human heme oxygenase-1: catalytic implications for heme cleavage
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