page_title: Neurogenesis
hierarchical_section_title: Neurogenesis
caption_attribution_description: Neural progenitor cells (small-size jpg version of Journal.pone.0001604.g001.png)&#160;: After forming a neurosphere, embryonic neural progenitor cells spread out into a monolayer. A. Neurosphere consisting of SVZ cells isolated at E15 that have aggregated in suspension after 2 days in culture. Scale bar: 100 µm. B. Neurosphere of SVZ cells derived at E15 that has attached to the floor of the culture flask after 4 days in culture. Note cells migrating away from the neurosphere. Scale bar: 100 µm. C. Cells at the periphery of neurospheres were chosen for electrophysiological recording. Most of the recorded cells extended processes. Arrows indicate the location of recording (left) and puffer (right) pipettes. Scale bar: 20 µm.
context_page_description: Neurogenesis is the process by which nervous system cells, the neurons, are produced by neural stem cells. It occurs in all species of animals except the porifera and placozoans. Types of NSCs include neuroepithelial cells, radial glial cells, basal progenitors, intermediate neuronal precursors, subventricular zone astrocytes, and subgranular zone radial astrocytes, among others.
  Neurogenesis is most active during embryonic development and is responsible for producing all the various types of neurons of the organism, but it continues throughout adult life in a variety of organisms. Once born, neurons do not divide, and many will live the lifespan of the animal.
context_section_description: Neurogenesis is the process by which nervous system cells, the neurons, are produced by neural stem cells (NSCs). It occurs in all species of animals except the porifera (sponges) and placozoans. Types of NSCs include neuroepithelial cells (NECs), radial glial cells (RGCs), basal progenitors (BPs), intermediate neuronal precursors (INPs), subventricular zone astrocytes, and subgranular zone radial astrocytes, among others.
  Neurogenesis is most active during embryonic development and is responsible for producing all the various types of neurons of the organism, but it continues throughout adult life in a variety of organisms. Once born, neurons do not divide (see mitosis), and many will live the lifespan of the animal.
caption: A neurosphere of neural stem cells in rat embryo spreads out into a single layer of cells. A) Neurosphere of subventricular zone cells after two days in culture. B) Shows the neurosphere at four days in culture and cells migrating away. C) Cells at the periphery of the neurosphere mostly having extending processes.
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